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Boston 

Medical  Library 

8  The  Fenway 


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THE 


MEDICAL  RECORD 


A   Weekly  yournal  of  Medicine  and  Surgery 


EDITED    BY 

GEORGE   F.  SHRADY,  A.M.,  M.D. 

SURGBON  TO  THB  PKESBYTERfAN  AND  ST.   FRANCIS  HOSPITALS;    CONSULTING  SURGBON  TO  THB  HOSPITAL  FOR  RUPTURBD 
AND  CRIPPLBD,   NEW  YORK;    AND  PRESIDENT  OF  THE  N.   Y.    PATHOLOGICAL  SOCIETY. 


^alumje  26 


JULY   5,    1884  — DECEMBER  27,    1884 


i\ 


NEW    YORK 
WILLIAM    WOOD    &    COMPANY 

1884 


Trow's 

Printing  and  Bookbinding  Company, 

201-213  East  I2ik  Streety 

New  York. 


LIST  OF  CONTRIBUTORS  TO  VOL.  XXVI. 


Agnew,  Dr.  C.  IL,  New  York. 
Am)rews,  Dr.  Joseph  A.,  New  York. 
AvERiLL,  Dr.,  Campello,  Mass. 

Baird,  Dr.  W.  T.,  Albany,  Tex. 
Baker,    Dr.    Henry    B.,    Lansing, 

Mich. 
Baker,  Rev.  Geo.  S.,  New  York. 
Baldwin,  Dr.  Benjamin  I.,  Mont- 
gomery, Ala. 
Baldwin,    Dr.    D.    A.,    Englewood, 

N.J. 
Baruch,  Dr.  Simon,  New  York. 
BiNNiE,  Dr.  John,  Poynette,  Wis. 

BODENHAMER,      Dr.    WiLLIAM,     NeW 

York. 
BoRCHEiM,  Dr.  L.  E.,  Atlanta,  Ga. 
BoswoRTH,  Dr.  Franche  H.,  New 

York. 
Boyland,  Dr.  G.  Halsted. 
Bradner,    Dr.    Wm.    B.,   Warwick, 

N.  Y. 
Brown,  Dr.  K  Wood,  Kansas  City, 

Mo. 
Browning,  Dr.  Wm.,  Brooklyn,  N.  Y. 
Buck,  Dr.  Albert  H.,  New  York. 
BuNDY,  Dr.  A.  D.,  St.  Ansgar,  Va. 
Burke,  Dr.  John,  New  York. 

Canfield,  Dr.  H.  A.,  Gillmore,  Pa. 
Campbell,    Dr.    S.    K,   South    Bay 

City,  Mich. 
Carhart,  Dr.  J.  W.,  Tampasas,  Tex. 
Carman,  Dr.  J.  H.,  South  Amboy, 

N.J. 
Carpenter,  Dr.  Wesley  M.,  New 

York. 
Case,  Dr.  Meigs,  New  York. 
Cai;ij>well,  Dr.  C.  M.,  New  York. 
Chamberlain,    Dr.  Wm.   M.,    New 

York. 
Chapin,    Dr.  Henry  Dwight,  New 

York. 
Cheesman,  Dr.  W.  S.,  Auburn,  N.  Y. 
Childs,  Dr.S.  B.,  Brooklyn,  N.Y. 
Christian,  Dr.  E.  P., Wyandotte,  Wis. 
Cowan,  Dr.  George,  Danville,  Ky. 
Crawcour,  Dr.  J.  L.,  New  Orleans, 

La. 
Crothers,    Dr.    T.    D.,     Hartford, 

Conn. 
Crudeli,    Dr.    Conrad    Tommasi, 

Rome,  Italy. 
Cuming,  Dr.  James,  Belfast,  Ireland. 


Dana,  Dr.  Chakfs  L.,  New  York. 
Dana,  Dr.  S.  W .,  Now  York. 
Davis,  Dr.  G.  G.,  Trewsbury,  N.  Y- 
Dickinson,  Dr.  D.,  U.S.N. 
Doughty,  Dr.  W.  H.,  Augusta,  Ga. 
Dumm,  Dr.  S.  C,  Columbus,  O. 
DwiGHT,*Dr.  Francis  M.,  New|York. 

Earle,  Dr.  Charles  W.,  Chicago, 

111. 
Edson,    Dr.    Benjamin,    Brooklyn, 

N.Y. 
Edson,  Dr.  Cyrus,  New  York. 
Ellingwood,  Dr.  Finley,  Manteno, 

111. 
Elliott,  Dr.  A.  A.,  Steubenville,  O. 
Epley,  Dr.   F  W.,  New  Riclimond, 

Wis. 
Evans,  Dr.  S.  A.,  Conway,  N.  H. 

FiSK,  Dr.  Samuel  Aug.,  Denver,  Col 

FoTHERGiLL,  Dr.  J.  MiLNER,  Lon- 
don, Eng. 

Fowler,  Dr.  Geo.  B.,  New  York. 

Free,  Dr.  Spencer  M.,  Dagus 
Mines,  Pa. 

French,  Dr.  C.  H.,  Waterbury,  Conn. 

Fuller,  Dr.  Eraser  C,  New  York. 

Fuller,  Dr.  S.  E.,  Brooklyn,  N.  Y. 

Gardiner,  Dr.  Henry  K.,  Provi- 
dence, R.  I. 

Gatchell,  Dr.  Edwin  A.,  Asheville, 
N.  C. 

Garrigues,  Dr.  H.  J.,  New  York. 

Geddings,  Dr.  W.  H.,  Aiken,  S.  C. 

GiDDiNGS,  Dr.  W.  P.,  Gardiner,  Me. 

GoLDSMrra,  Dr.  Middleton,  Rut- 
land, Vt. 

Good  WILLIE,  Dr.  D.  H.,  New  York. 

Graves,  Dr.  Thomas,  Virginia. 

Green,  Dr.'EowARD  H.,  U.  S.  Navy. 

Groat,  Dr.  F.  A.,  Fremont,  O. 

Hamilton,    Dr.    Allan    McLane, 

New  York. 
Harlan,  Dr.  A.  W.,  Chicago,  111. 
Harris,  Dr.  M.  L.,  Chicago,  111. 
Harris,  Dr.  R.  B.,  Savannah,  Ga. 
Hawes,  Dr.  Jesse,  Greeley,  Col. 
Heineman,  Dr.  H.  N.,  New  York. 
Henry,  Dr.  Morris  H.,  New  York. 
Hepburn,  Dr.  N.  J.,  New  York. 


HEUEL,'Dr.  Franz,  New  York. 
HoLDEN,  Dr.  Edgar,  Newark,  N.  J. 
Holt,  Dr.  L.  Emmet,  New  YorK. 
HoRTON,  Dr.  W.  P.,  Jr.,  Cleveland,  O. 
HoRwiTZ,  Dr.  Lloyd  Norris,  Phila- 
delphia, Pa. 
Howe,  Dr.  J.  Morgan,  New  York. 
Humphreys,  Dr.  C.  H.,  Dayton,  O. 
Hunter,  Dr.  James  B.,  New  York. 

Jarvis,  Dr.  Willlam  Chapman,  New 

York. 
Jones,  Dr.  S.  S.,  New  York. 
JuDKiNS,  Dr.  William,  Cincinnati,  O. 

Kales,  Dr.  J.  W.,  Franklinville,  N.  Y. 

Kelly,  Dr.  J.  D.,  Utica,  N.  Y.;^ 

KiDD,  Dr.  George  H., '^Dublin,  Ire- 
land. 

King,  Dr.  Samuel  T.,  New  York!. 

Kinnicutt,  Dr.  Frank  P.,  New  York. 

Klingensmith,  Dr.  I.  P.,  Blairsville, 
Pa. 

Knapp,  Dr.  H.,  New  York. 

KoRTRiGHT,  Dr.  James  L.,  Brooklyn, 
N.Y. 

Kretschmar,  Dr.  Paul  H.,  Brook- 
lyn, N.Y. 

I^NCASTER,  Dr.  R.  A.,  Gainesville, 

Fla. 
Leake,  Dr.  Henry  K.,  Dallas,  Tex. 
Leonard.   Dr.    William    R.,   New 

York. 
Lewis,  Dr.  Daniel,  New  York. 
Lincoln,  Dr.  Rufus  P.,  New  York. 

McCoy,  Dr.  George  T.,  Columbus,  O. 
McLean,  Dr.  Leroy,  Troy,  N.  Y. 
Mackenzie,  Dr.  John  N.,  Baltimore, 

Md. 
Mackenzie,  Dr.  Morell,  London, 

Eng. 
Major,  Dr.  George  W.,  Montreal, 

Canada. 
Mammen,  Dr.  Ernest,  Bloomington, 

111. 
Marsh,  Dr.  E.  J.,  Paterson,  N.  J. 
Marshall,  Dr.  John  S.,  Chicago,  111. 
Marvin,  Dr.,  East  Saginaw,  Mich. 
Meier,  Dr.  G.  C.  H.,  New  York. 
Millard,  Dr.  H.  B.,  New  York. 
Minor,  Dr.  James  L.,  New  York. 
Moore,  Dr.  A.  M.,  U.  S.  Navy. 


IV 


CONTRIBUTORS   TO   VOL.   XXVI. 


Moore,  Dr.  William  Oliver,  New 

York. 
Mulhane,    Dr.   John   D.,  Steuben- 

ville,  O. 
MuNDf ,  Dr.  Paul  F.,  New  York. 
Murray,  Dr.  R.,  U.  S.  Army. 

Nelson,  Dr.  C.  E.,  New  York. 
Newcomb,  Dr.  J.  E.,  New  York. 
Nolan,  Dr.  E.  M.,  Jacksonville,  Fla. 
North,  Dr.  N.  L.,  Brooklyn,  N.  Y. 
Noyes,  Dr.  H.  D.,  New  York. 

Oliver,  Dr.  N.  E.,  Thornton,  111. 
Ord,  Dr.  William  M.,  London,  Eng. 
Otis,  Dr.  F.  N.,  New  York. 

Page,  Dr.  A.  C,  Truro,  N.  S. 

Page,  Dr.  K  Channing  M.,  New 
York. 

Palmer,  Dr.  J.  G.,  Oakbowery,  Ala. 

Panum,  Dr.  P.  L.,  Copenhagen,  Den- 
mark. 

Park,  Dr.  Roswell,  Buffalo,  N.  Y. 

Park,  Dr.  G.  C.,  Murraysville,  Pa. 

Parker,  Dr.  J.  B.,  U.  S.  Navy. 

Parker,  Dr.  William  S.,  Piqua,  O. 

Parker,  Dr.  W.  Thornton,  Fort 
Union,  N.  M. 

Parks,  Dr.  N.  O.  D.,  Ashton,  R.  I. 

Parmenter,  Dr.  John,  Buffalo,  N.  Y. 

Pbck,  Dr.  Edward  S.,  New  York. 

Percy,  Dr.  Samuel  R.,  New  York. 

Perry,  Dr.  Alfred  W.,  San  Fran- 
cisco, Cal. 

Peters,  Dr.  John  C,  New  York. 

PiNKNEY,  Dr.  Howard,  New  York. 

Polk,  Dr.  W.  M.,  New  York. 

Prendergast,  Dr.  P.  J.,  Brooklyn, 
N.  Y. 

Redfrrn,  Dr.  Peter,  Belfast,  Ire- 
land. 

Reynolds,  Dr.  Walter  B.,  Washing- 
ton, D.  C. 

Riley,  Henry  A.,  Esq.,  New  York. 

Roane,  Dr.  James,  Yankton,  Dak. 

RoBBiNs,  Dr.  C.  W.,  Marinette,  Wis. 

Rockwell,  Dr.  A.  D.,  New  York. 

Rodenstein,  Dr.  L.  A.,  New  York. 

RoosA,  Dr.  D.  B.  St.  John,  New 
York. 

RowE,  Dr.  Frank  H.,  Cummins- 
ville,  O. 

Saundby,  Dr.  Robert,  Birmingham, 

Eng. 
ScuDDER,  Dr.  H.  Martyn,  Chicago, 

111. 
SAe,  Prof.  Germain,  Paris,  France. 
Sexton,  Dr.  Samuel,  New  York. 


Shafer,  Dr.  J.  P.,  Parkersburg,  W. 

Va. 
Sheardown,  Dr.  T.  W.,  Knoxville, 

Tenn. 
Sheardown,  Dr.  Thomas  W.,  Wino- 
na, Minn. 
Shears,  Dr.  C.  H.,  New  York. 
Shrady,  Dr.  Geo.  F.,  New  York. 
Shillock,  Dr.  P.  T.,  Chaska,  Minn. 
Sizer,  Dr.  A.   B.    de  S.,  Brooklyn, 

N.  Y. 
Smiley,  Dr.  D.  B.,  Middletown,  N.  Y. 
Smith,  Dr.  Andrew  H.,  New  York. 
Smith,  Dr.  Eugene,  Detroit,  Mich. 
Smith,  Dr.  F.  W.,  Syracuse,  N.  Y. 
Smith,  Dr.  H.  Lyle,  Hudson,  N.  Y. 
Smith,  Dr.  J.  Lewis,  New  York. 
Smith,  Dr.  Samuel  W.,  New  York. 
Smyth E,  Dr.  G.  C,  Greencastlc,  Ind. 
Sohlin,  Dr.  Charles,  St.  Paul,  Minn. 
Sperry,  Dr.  S.  B.,  Delafield,  Wis. 
SprrzKA,  Dr.  E.  C,  New  York. 
Stanton,  Dr.  John  G.,  New  London, 

Conn. 
Sternberg,  Dr.  Geo.  M.,  U.  S.  Army. 
Stevens,  Dr.  B.  N.,  Chillicothe,  Mo. 
Stickler,  Dr.  J.  W.,  Orange,  N.  J. 
Stimson,  Dr.  Lewis  A,,  New  York. 
Stockard,   Dr.    C.    C,   Columbus, 

Miss. 
Stone,  Dr.  R.  M.,  Omaha,  Neb. 
Streeter,  Dr.  F.  B. 
Streeter,    Dr.    H.  W.,    Rochester, 

N.Y. 

Tauszky,  Dr.  Rudolph,  New  York. 
Taylor,  Dr.  W.  H.,  New  Bedford, 

Mass. 
Teller,  Dr.  S.,  New  York. 
Thayer,  Dr.   C.  C,  Clifton  Springs, 

N.  Y. 
Thompson,  Dr.  John  H.,  New  York. 
Tyson,  Dr.  James,  Philadelphia,  Pa. 

Uhler,  Dr.  J.  R., ^Baltimore,  Md. 

ViDAL,  Dr.  Etienne  C. 

Wackerhagen,  Dr.  G.,  Brooklyn, 
N.Y. 

Wallian,  Dr.  Samuel  S.,  Blooming- 
dale,  N.Y. 

Ward,  Dr.  E.  B.,  Greensborough, 
Ala. 

Weber,  Dr.  Leonard,  New  York. 

Webster,  Dr.  David,  New  York. 

Weisse,  Dr.  Faneuil  D.,  New  York. 

Weld,  Dr.  G.  W.,  New  York. 

Wendt,  Dr.  Edmund  C,  New  York. 


White,  Dr.  Leonard  D.,  Uxbridge, 

Mass. 
Wilder,  Dr.  Burt  G.,  Ithaca,  N.  Y. 
WiLFERT,  Dr.  H.,  Cincinnati,  O. 
Williamson,   Dr.    C.    H.,   Steamer 

Acapiilco. 
Wilson,  Dr.  F.  M.,  Bridgeport,',Conn. 
Winters,  Dr.  Joseph  E.,  New  York. 
Wright,  Dr.  J.  W.,  New  York. 
Wylie,  Dr.  W.  Gill,  New  York. 
Wyman,  Dr.  Hal  C,  Detroit,  Mich. 

Zenner,  Dr.  Philip,  Cincinnati,  O. 

Institutions  and  Societies  from  which 
Reports  have  been  received. 

American  Gynecological  Society. 

American  Ophthalmological  So- 
ciety. 

American  Otological  Society. 

American  Public  Health  Associ- 
ation. 

Berlin  Society  of  International 
Medicine. 

Biological  Society  of  Paris. 

British  Medical  Association. 

Cook  County  Hospital,  Chicago, 
III. 

Hospitals  Medical  Society  of 
Paris. 

German  Naturalists  and  Physi- 
cians. 

Imperial  Medical  Society  of  Vi- 
enna. 

International  Medical  Congress 

Medical  Society  of  Berlin. 

Medical  Society  of  the  County  of 
New  York. 

Medical  Society  of  Virginia. 

Michigan  State  Medical  Society. 

New  York  Academy  of  Medicine. 

New  York  Eye  and  Ear  Infir- 
mary. 

New  York  Hospital. 

Northwestern  Medical  and  Sur- 
gical Society. 

New  York  Neurological  Society. 

New  York  Pathological  Society. 

New  York  State  Medical  Associ- 
ation. 

Paris  Academy  of  Medicine. 

Philadelphia  Hospital. 

Practitioners*  Society  of  New 
York. 

Roosevelt  Hospital. 

St.  Catherine's  Hospital,  Brook- 
lyn, N.  Y. 

Surgical  Society  of  Paris. 

Therapeutical  Society  of  Paris. 


The   Medical   Record 

A    Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  I 


New  York,  July  5,  1884 


Whole  No.  713 


®ri0itml  J^rticles. 


SOME    REMARKS   ON  AFFECTIONS   OF    THE 
HEART. 

Bv  J.    MILNER  FOTHERGILL,  M.D.   Edin.,   Hon.  M.D., 
Rush  Med.  Coll.,  Ilu 

ASSOQATB  FOLLOW  OP  THB  COLLBGB  OP  PHYSICIANS  OP  PHTLADBLPHIA,  PHYSICIAN 
TO  THE  QTY  OP  LOKDON  HOSPITAL  POR   DISEASES  OP  THB  CHEST. 

I. 

GROSS    MIjSCULAR    CHANGES. 

A  PREUMiNARY  word  is  desirable  about  these  articles  in 
order  to  prevent  misconception.  In  a  special  treatise 
the  matter  must  be  thoroughly  gone  into  from  the  bottom 
upward,  as  many  readers  will  approach  the  subject  in 
simple  ignorance  o^it.  But  here  it  is  assumed  that  the 
reader  already  possesses  a  fair  text-book  acquaintance 
with  the  heart  and  its  various  affections.  With  this  ex- 
planation no  mistake  ought  to  occur. 

The  heart  is  liable  to  undergo  certain  changes  of  form 
known  familiarly  as  hypertrophy  and  dilatation,  and  also 
atrophy  in  wasting  disease.  The  latter  needs  no  consid- 
eration here ;  it  is  but  part,  and  not  an  important  part, 
usually,  of  a  general  condition. 

Dilatation,  or  elongation  of  the  muscular  fasciculi  of 
the  heart,  is  found  in  conditions  where  the  chambers 
yield ;  conditions  which  vary  considerably,  viz.,  the 
heart-fibres  yield  under  undue  distention  (which  they  are 
unequal  to  overcome),  or  are  themselves  weakened  and 
so  deprived  of  their  normal  vigor.  Whether  in  a  case  of 
high  arterial  tension  hypertrophy  or  dilatation  takes  place 
is  a  question  of  tissue-nutrition. 

Hjrpertrophy  is  usually  described  as  a  muscular  devel- 
opment to  overcome  some  obstacle,  as  stenosis  at  the 
aortic  orifice,  or  high  arterial  tension,  as  in  the  gouty 
heart.  In  both  cases  there  is  an  obstruction  offered  to 
the  ventricular  systole,  which  the  muscle  meets  by  en- 
largement ;  a  very  intelligent  action  on  the  part  of  the 
heart,  it  must  be  admitted.  But  this  view  of  some  <^  in- 
telligence" in  the  heart,  by  which  its  nutrition  is  modi- 
fied to  meet  emergencies,  is  misleading.  Is  there  some 
intelligence  in  the  arm-muscles  of  the  blacksmith,  or  in 
the  mascles  of  the  calf  of  the  leg  of  a  ballet-dancer  ? 
None  that  I  ever  heard  of.  What  then  is  the  explana- 
tion of  these  well-known  facts  ?  It  is  this  :  motor  nerves 
are  linked  with  trophic  nerves ;  the  message  to  the  mus- 
cle to  contract  is  accompanied  by  another  message  along 
the  trophic  nerve,  which  dilates  its  associated  blood-ves- 
sels, and  increases  its  blood  supply.  Consequently,  in- 
a-eased  functional  activity  in  a  muscle  is  followed  by 
increased  growth  in  it.  This  is  spoken  of  as  **  hyper- 
trophy," and  whether  it  depends  upon  growth  in  existing 
fibnllas  or  increase  in  the  number  of  fibrillae  need  not 
detain  us  here.  But  if  the  general  nutrition  is  deficient, 
great  action  of  a  muscle  leads  not  to  hypertrophy,  but 
to  wasting,  as  seen  in  the  well-known  case  of  the  top- 
sawyer  so  graphically  described  by  T.  King  Chambers, 
in  his  famous  "  Clinical  Lectures,"  in  the  chapter  on 
•*  Atrophy  of  Muscles."  His  appetite  suddenly  failed, 
and  his  "  shoulder  muscles,"  those  in  most  use  by  him, 
grew  soft  and  weak  from  malnutrition.  The  reader  who 
has  this  work  at  hand  can  profitably  consult  it  at  this 
pobt  He  will  see  that  great  use  of  a  muscle  may  lead 
to  atrophy  as  well  as  to  hypertrophy,  according  to  the 


demand  upon  the  muscle,  and  its  nutritive  supply.  This 
is  the  great  lesson  which  I  desire  the  reader  to  take  to 
heart,  about  hypertrophy  and  dilatation  of  the  heart ;  and 
after  this  has  been  thoroughly  realized  it  will  not  be  diffi- 
cult to  put  the  subject  of  gross  muscular  changes  in  the 
heart-walls  before  him  in  a  manner  which  will  explain 
them  without  any  hypothesis  of  "intelligence"  in  the 
heart. 

The  muscular  structure  of  the  heart-wall  is  ruled  by  its 
own  ganglia  in  the  heart  itself.  The  primitive  pulsatile 
sac  has  a  nerve-centre  with  an  afferent  and  an  efferent 
nerve-fibril.  By  the  afferent  nerve-fibril  the  sense  of  dis- 
tention is  conveyed  to  the  centre,  whereupon  an  efferent 
message  is  despatched  to  the  muscle  to  contract.  Such 
a  heart  is  a  simple  hollow  muscle  with  its  ruling  nerve- 
centre.  When  the  sac  is  full  it  contracts  by  means  of 
the  simple  nerve-mechanism.  The  human  heart  is  a 
very  complex  hollow  muscle,  with  valves  to  economize 
power  \  while  its  primitive  nerve-ganglia  have  connec- 
tions with  the  rest  of  the  nervous  system  by  which  the 
condition  of  diastole  and  systole — filling  and  emptying — 
is  regulated  according  to  the  wants  of  the  system.  These 
are  m  the  vagus  inhibitory  and  also  accelerator  nerve - 
fibrils.  The  first  come  into  action  and  to  hold  back  the 
ventricular  systole  when  the  arterial  system  is  full — the 
slow  stroke  of  high  arterial  tension.  The  latter  is  found 
in  action  with  a  low  blood-pressure — the  fast,  easily  com- 
pressible pulse,  which  contrasts  with  the  opposite  condi- 
tion. 

Still,  the  great  matter  to  bear  in  mind  is  the  primi- 
tive hollow  muscle  with  its  nerve-centre  and  its  afferent 
and  efferent  fibrils.  The  sense  of  distention  is  followed 
by  a  contractile  action.  When  the  hollow  muscle  is  un- 
wontedly  distended  a  proportionately  vigorous  contrac- 
tion follows.  That  is  one  matter.  If  the  nutrition  is 
well  sustained  the  muscle  waxes  greater,  in  other  words, 
becomes  hypertrophied.  That  is  another.  It  is  the  dis- 
tention which  leads  to  the  muscular  growth !  That  is 
the  predominant  idea  to  be  borne  lucidly  in  mind  ;  and 
then  why  dilatation  should  occur  in  one  case,  while  hy- 
pertrophy without  perceptible  enlargement  of  the  ventric- 
ular chamber  is  seen  in  a  second,  and  a  blend  of  the  two 
is  encountered  in  a  third  case,  becomes  a  matter  readily 
and  easily  comprehended. 

The  heart-chambers  are  not  of  fixed  size,  they  vary 
according  to  circumstances.  This  is  readily  seen  by 
taking  a  spare,  muscular  subject,  fixing  the  precise  spot 
of  the  heart's  apex-beat,  and  placing  the  tip  of  the  finger 
thereupon.  The  heart  can  be  felt  at  each  systole  quite 
distinctly.  Then  tell  him  to  hold  his  breath.  What  is 
the  result  ?  As  the  right  ventricle  becomes  more  and 
more  distended  and  intervenes  as  a  "  water-cushion  *'  be- 
twixt the  heart's  apex  and  the  chest-wall,  the  apex-beat 
is  lost.  As  soon  as  the  right  ventricle  is  relieved  by  the 
respirations  being  resumed,  it  recovers  its  normal  size, 
and  the  apex-beat  is  quickly  as  palpable  as  before. 

The  heart,  then,  undergoes  changes  of  form,  and  may 
be  temporarily  distended.  This  may  be  observed  by 
causing  a  man  to  make  an  effort  (as  with  a  health-lift, 
for  instance),  and  examining  the  heart  while  the  effort  is 
being  made.  Dilatation  of  the  heart  is  prolonged  dis- 
tention.  But  at  what  point  the  condition  of  distention 
will  be  arrested  by  compensatory  growth  in  the  muscular 
wall  depends  upon  the  circumstances  of  each  individual 
case. 

In  one  case  (a  well-nourished  person),  the  compensa- 


THE   MEDICAL   RECORD, 


[July  5,  1884. 


tory  growth  will  be  set  up  so  early  that  no  perceptible  dila- 
tation occurs.  In  another,  a  condition  of  distinct  dilata- 
tion is  reached  before  hypertrophy's  arresting  hand  can  be 
brought  to  bear.  In  a  third,  there  is  dilatation  without 
perceptible  growth  or  thickening  in  the  muscular  walls. 
According  to  the  amount  of  hypertrophy  in  proportion 
to  the  extent  of  the  dilatation  will  be  the  amount  of 
vigor  in  the  heart.  We  speak  of  this  muscular  growth  in 
the  terms :  i,  complete  compensation ;  2,  incomplete 
compensation  ;  and  3,  no  compensation.  With  the  first 
the  patient  possesses  peat  vigor,  with  the  second  some 
vigor,  and  with  the  third  he,  or  rather  she,  is  a  crippled 
being.  Why  do  I  here  say  "  rather  she,"  not  being  a 
person  in  the  habit  of  speaking  of  the  "  weaker *'  sex  in 
a  derogatory  manner  ?  Because  dilatation  of  the  heart  is 
usual  with  women  under  circumstances  where  hypertro- 
phy is  rather  the  rule  with  men.  In  this  sense  of  tissue- 
nutrition  women  are  "  weaker "  than  men.  Take  the 
gouty  heart,  for  instance,  with  all  its  concomitants  (to  be 
discussed  in  a  later  article),  with  men  we  commonly  find 
pure  hypertrophy ;  with  women  there  is,  as  a  rule,  dilata- 
tion, with  more  or  less  (and  often  less)  hypertrophy. 

The  question  of  when,  and  at  what  point,  the  process 
of  dilatation  will  be  checked  by  compensating  muscular 
growth,  is  mainly  a  matter  of  tissue-nutrition.  There  is 
another  factor  in  action,  however,  and  that  is  "time;" 
in  other  words,  the  urgency  of  the  demand  upon  the 
heart-walls,  the  call  for  hypertrophy.  If  it  come  quickly, 
as,  for  instance,  when  an  aortic  valve  cusp  is  torn  down 
by  a  violent  effort,  some  dilatation  is  inevitable,  no  mat- 
ter what  the  nutritive  powers  of  the  individual.  When 
the  aortic  valves  are  being  soldered  together  slowly  by  a 
sclerosing  valvulitis  in  an  elderly,  well-fed  man,  the  de- 
mand is  so  gradual  that  the  h)rpertrophied  wall  is  found 
practically  without  any  enlaigement  of  the  ventricular 
chamber.  So  the  problem  rests  on  the  urgency  of  the 
demand  versus  the  nutritive  powers  of  the  organism. 
Having  grasped  this  main  idea,  the  reader  will  experience 
no  difficulty  in  recognizing  the  proportion  of  hypertrophy 
to  that  of  the  dilatation  in  any  case  which  comes  before 
him.  Or  in  realizing  the  fact  that  the  two  are  found  to- 
gether in  every  possible  proportion,  like  the  mixing  of 
"  old  rye  "  and  water.  Or  in  understanding  how,  when  the 
system  is  unequal  to  setting  up  complete  compensatory 
hypertrophic  growth  of  itself,  it  may  be  much  aided  by 
reducing  the  demand  upon  the  heart  (by  rest  in  the  re- 
cumbent posture),  and  by  increasing  the  energy  of  the 
ventricular  contractions  (by  remedied  agents  possessing 
such  action)  and  improving  the  general  nutrition.  The 
malady  and  the  means  of  remedying  it,  so  read,  are  clear 
and  unmistakable — to  my  mind  at  least. 

When  the  heart-muscle  has  been  temporarily  weakened 
by  acute  disease,  whether  a  general  condition  of  pyrexia 
or  the  causal  condition  is  one  of  myocarditis  accompany- 
ing pericarditis  or  endocarditis,  it  is  apt  to  become  di- 
lated ;  temporarily,  certainly,  in  all  cases.  But  whether 
the  condition  of  dilatation  will  remain  permanently  or  be 
removed,  and  at  what  rate  it  will  be  recovered  from,  will 
depend  upon  the  amount  of  the  demand  upon  the  heart 
{Le.y  the  extent  to  which  effort  must  be  made),  and  the 
amount  of  rest  which  can  be  given  to  it,  as  one  matter, 
and  the  assimilative  processes,  aided  by  agents  which  in- 
crease the  energy  of  the  ventricular  contractions,  as  the 
other. 

By  time,  patience,  and  well-directed  measures  (suppos- 
ing the  patient  to  be  able  to  command  all),  the  system 
may  be  enabled  to  build  up  compensatory  hypertrophy 
where,  when  unguided  by  knowledge  and  unaided  by  art, 
it  is  unequal  to  such  effort.  Such  at  least  has  been  my 
personal  experience. 

It  may  now  be  well  to  proceed  to  discuss  the  circum- 
stances under  which  such  gross  muscular  changes  are 
usually  found,  viz.,  obstruction  to  be  overcome  or  an  in- 
crease in  the  distending  force  to  be  resisted.  Two  mat- 
ters which  produce  somewhat  different  results. 

To  commence  with  the  aortic  orifice.     With  stenosis 


or  obstruction  at  this  orifice  the  left  ventricle  is  ordinarily 
found  simply  h)rpertrophied ;  sometimes,  in  women 
mainly,  there  is  some  dilatation.  We  can  understand 
this  readily  when  we  remember  that  the  lesion  is  slowly 
developed,  allowing  ample  time  for  the  building  up  of 
the  compensating  hyperplasia ;  and,  to  my  mind  still 
more,  no  great  increase  in  the  distending  force.  Here 
all  that  is  required  is  some  addition  to  the  driving-power 
of  the  ventricle  by  which  a  normal  bulk  of  blood  may  be 
driven  in  a  normal  time  through  a  narrowed  orifice.  It 
is  a  slow  process  altogether,  and  the  comparatively  small 
hypertrophy  is  well  maintained. 

Far  otherwise  is  the  history  of  aortic  regurgitation. 
Here  the  free  edges  of  the  valve-cusps  are  affected,  with 
or  without  some  dilatation  of  the  aortic  conus,  and  a 
regurgitant  current  of  blood  is  driven  backward  into  the 
left  ventricle  by  the  aortic  recoil.     It  may  be  but  a  thin 
riband  of  blood,  but  it  is  sent  into  the  chamber  by  a  very 
different  force  to  that  which  pours  its  current  into  the 
ventricle  through  the  mitral  orifice.     The  latter  wells  in 
rather,  while  the  regurgitant  current  is  driven   in  by  the 
powerful  recoil  of  the  elastic  arteries  distended  by  the 
ventricular  systole.     Forcible  distention  of  the  muscular 
wall  follows,  and  that  brings  with  it,  in  its  turn,  hyper- 
trophic growth,  and  we  find  a  massive,  powerful  ventricle. 
So  far  so  good.     If  the  valvular  mischief  be  the  result  of 
an  acute  valvulitis,  and  the  mutilation  of  the  valve  be  at 
once  small  and  static,  and  the  muscijlar  development  is 
in  proportion  to  it,  years  may  roll  over  the  patient's  head 
without  perceptible  change  for  the  worse.     Such,  how- 
ever, is  not  the  usual  history  of  a  case  of  aortic  regurgi- 
tation.    Rather  is  it  as  follows:  The  enlarged  ventricle 
is  capable  of  throwing  its  contents  into  the  arterial  system 
with  much  energy,  while  in  consequence  of  the  enlarge- 
ment of  its  chamber  the  amount  of  blood  ejected  at  each 
systole  is  much  above  the  normal  amount ;  the  distended 
elastic  arteries  recoil  with  an  energy  proportioned  to  the 
distending  force,  and  a  powerful  current  is  driven  back- 
ward into  the  ventricle.     More  distention  of  the  muscular 
chamber  leads  to  more  hjrpertrophy,  and  then  the  huge 
cor  bovinum  of  aortic  regurgitation  is  foand ;    but  the 
limits  of  compensatory  growth  are  at  last  reached.     The 
huge  muscle  is  insufficiently  fed,  and  in  time  it  undergoes 
degenerative  change ;   and  then  the  heart  comes  to  a 
standstill  in  diastole,  the  decayed  fibrillae  being  unable  to 
contract  on  full  distention.     From  this  we  can  compre- 
hend the  prognostic  difference  betwixt  aortic  stenosis  and 
aortic  insufficiency  in  regard  to  time.     In  the  one  there 
is  only  an  obstacle  to  be  overcome  ;  in  the  other  a  new 
distending  force  is  in  action.     In  the  one  hypertrophy  is 
moderate  and  well  sustained ;  in  the  other  it  is  huge  and 
soon  wears  out. 

Now  let  i}s  consider  the  results  of  morbid  action  in  the 
mitral  valves.     In  stenosis  the  lefl  ventricle  is  of  normal 
size,  or  even  below  it,  for  the  narrowed  orifice  obstructs 
the  blood-fiow  into  the  chamber.     But  if  the  obstruction 
be  slight,  little  change  will  be  found  in  the  left  ventricle. 
Far  otherwise  is  it  in  mitral  regurgitation.      Here  the  left 
ventricle  has  no  obstruction  to  overcome  ;  indeed  there 
are  two  outlets  for  the  blood  now  instead  of  one,  and  yet 
it  is  enlarged.     How  is  that  ?     Because  the  blood  enter- 
ing it  on  diastole  is  sent  in  with  abnormal  force  from  the 
gorged  pulmonic  circulation,  plus  the  enlarged  left  auricle. 
There  is  no  obstruction  to  the  blood-flow  offered  at  the 
mitral  ostium,  and  the  more  powerful  current  dilates  the 
left  ventricle,  with  the  consequence  of  increased  muscular 
growth. 

When  the  pulmonic  circulation  is  impeded,  whether  by 
mitral  disease  or  disease  in  the  respiratory  organs,  the 
right  ventricle  enlarges.  Incompletely  emptied  on  systole, 
the  swollen  veins  behind  it  pour  in  their  contents,  and 
distention  follows,  with  enlargement  of  the  muscular 
wall.  As  there  is  always  an  increase  in  the  distending 
force  in  the  case  of  the  right  ventricle,  so  there  is  always 
enlargement  of  the  chamber,  as  well  as  a  thickening  of 
its  muscular  wall.     But  here  again    the    proportions  of 


July  5,  1884.] 


THE   MEDICAL  RECORD. 


dilatation  to  those  of  h3rpertrophic  growth  vary  according 
to  the  urgency  of  the  demand  and  the  powers  of  nutrition. 
The  same  measures  are  to  be  adopted  here  as  were 
recommended  in  the  case  of  the  enlarged  left  ventricle, 
viz,,  rest,  good  food,  and  agents  which  increase  the  en- 
ergy of  the  cardiac  contractions. 

Such,  then,  are  the  ordinary  circumstances  under  which 
the  walls  of  the  heart  undergo  changes  in  form.  The 
dilating  process  comes  first,  and,  if  the  powers  are  equal 
to  it,  hypertrophic  growth  follows.  At  what  stage  of  the 
dilating  process  the  compensating  growth  begins  to  be 
efficient  varies  in  each  and  every  case ;  depending  upon 
causes  sketched  out  here  in  bold  outline  rather  than  in 
detail.  To  include  the  latter  would  be  to  extend  this 
article  beyond  any  limits  that  can  be  furnished  by  a 
journal.  But  that  is  no  reason  why  the  reader,  having 
grasped  effectively  the  outline  here  provided,  should  not 
work  out  the  details  in  those  cases  which  come  imme- 
diately under  his  notice. 

Rest,  digitalis,  and  iron  (with  some  strychnia),  with 
good  food,  form  a  good  line  of  treatment  when  nature 
cannot  surmount  her  difficulty  single-handed ;  but  what 
must  be  done  in  each  case  depends  upon  its  own  require- 
ments, of  which  the  medical  man  in  attendance  can  alone 
be  the  judge. 

PRACTICAL  OBSERVATIONS  ON  THE  HUMAN 
EAR  AND  ITS  DISEASES,  WITH  ILLUSTRA- 
TIVE   CASES. 

By  SAMUEL  SEXTON,  M.D., 

AURAL  SUKGBON  TO  THK  NEW  YORK  EYB  AND  BAR  INFIRMARY. 

I. — ^The  External  Ear. 

(Continued  from  Vd.  xxv.,  p.  374.) 
HiEMATOMA   AURIS. 

Synonym. — Othaematoma ;  Perichondritis  Auriculae. 

Hamaioma  auris  is  a  disease  of  the  cartilage  and 
perichondrium  of  the  auricle,  with  consequent  formation 
of  a  cyst  containing  blood  or  varying  portions  of  its 
constituents.  These  sanguineous  cysts,  as  they  are 
sometimes  called,  may  be  limited  to  a  slight  extrava- 
sation scarcely  distinguishable  from  deep  congestion,  or 
they  may  consist  in  a  tumor  of  greater  or  less  dimensions. 
The  tumor,  although  not  always  containing  pure  blood, 
has  generally  received  the  designation  of  blood-tumor. 
It  may  be  produced  either  by  severe  contusion  of  the 
auricle,  or  it  may,  it  is  alleged,  take  its  origin  from  idi- 
opathic causes  alone  ;  most  frequently,  however,  it  seems 
to  be  due  to  violence,  even  where  a  predisposition  to  its 
occurrence  exists.  It  is  characterized  by  more  or  less 
inflammation  of  the  cartilage  and  perichondrium  of  the 
ear,  and  by  the  sudden  escape  of  sanguineous  fluid  be- 
tween the  cartilage  and  perichondrium,  and,  it  is  said, 
into  the  substance  of  the  cartilage  itself.  The  size  of 
tiie  tumor  varies  from  that  of  a  Lima  bean  to  an  egg ; 
its  formation  is  usually  rapid,  and  the  contents,  at  first 
fluid,  show  a  marked  tendency  to  become  clotted,  and 
quite  often,  unless  incised,  spontaneous  rupture  takes 
place. 

In  the  milder  attacks  extravasation  is  so  slight  that  it 
has  been  characterized  as  a  serous  oedema.  The  disease 
most  frequently  occurs  in  the  insane,  and  produces  such 
characteristic  deformities  that  it  is  well  known  in  insane 
institutions  as  the  "  insane  ear,"  "  shrivelled  ear,"  and 
*'  asylum  ear."  The  inflammation  in  this  disease  is  gen- 
erally adynamic  in  character ;  in  certain  cases,  however, 
inflammation  is  liable  to  be  more  active.  In  a  very 
considerable  number  of  cases  there  is  a  strong  tendency 
shown  to  spontaneous  recovery. 

HISTORY. 

^  Traumatic  othematoma. — The  ancients  were  very 
familiar  with  this  morbid  condition  of  the  auricle,  since 
it  was  the  necessary  result  of  boxing-matches,  which 


then  constituted  the  favorite  mode  of  combat.  Among 
the  Greeks  and  Romans  pugilism  was  considered  an  es- 
sential part  of  education,  as  it  increased  the  strength  and 
developed  boldness  of  character  in  their  youth.  Defence 
and  assault  with  the  fist  or  cestus  were  then  extremely 
common,  and  combats  for  amusement  eveh  were  the 
fashion  of  the  day  ;  the  Grecian  boxers,  who  were  justly 
renowned,  had  for  their  titulary  deity  Pollux  himself. 
The  -^neid  abounds  in  praise  of  these  barbaric  contests ; 
thus  in  the  combat  between  Eutellus  and  ^neas — 

"  A  storm  of  strokes,  well  meant,  with  fury  flies. 
And  errs  about  their  temples,  ears,  and  eyes— 
Nor  always  errs,  for  oft  the  gauntlet  draws 
A  sweeping  stroke  along  the  crackling  jaws." 

The  implement  employed  by  the  classic  slugger  in  these 
auricle-cracking  feats  was  the  cestus,  a  formidable 
gauntlet  composed  of  thongs  of  several  thicknesses  of 
raw  hide  strongly  fastened  together  and  loaded  with  lead, 
iron,  or  brass,  and  bound  to  the  arm  by  thongs.  Four 
varieties  of  this  crushing  implement  are  known  to  have 
been  in  use,  the  least  deadly  being  more  dangerous  even 
than  the  modem  assassin's  '*  brass  knuckles,"  and  capable 
of  administering  a  fatal  blow.  These  murderous  weapons 
were  known  to  Virgil  as  the  *'  gloves  of  death.*'  Paulus 
^genita  refers  to  the  aural  injuries  produced  by  this 
weapon  as  contusions  of  the  ear,  and  Hippocrates  de- 
scribed them  as  fractures  of  the  auricle,  adding  that  the 
injury  was  a  common  one  in  his  day.  "  The  combat 
with  the  cestus,"  he  says,  "  was  a  favorite  amusement 
of  the  ancients,  and  a  blow  about  the  ears  was  reckoned 
a  master-stroke,  sometimes  being  fatal."  At  a  later  date 
the  amphotides,  a  helmet  or  headguard,  was  worn  to  pro- 
tect the  temporal  bones,  arteries,  and  ears.  It  was  con- 
structed with  thongs  and  ligatures  made  of  the  hides  of 
bulls,  studded  with  knobs  of  iron,  and  thickly  quilted 
inside  to  dull  the  concussion  of  blows.  The  pugilists 
and  the  pancratiasles,  armed  with  the  cestus,  were  in 
the  habit  of  producing  such  disfigurement  of  the  ears  that 
it  became  a  customary  plastic  ornament  in  antique 
sculpture,  which  thus  affords  abundant  evidence  of  the 
results  of  these  practices;  for  example,  the  heads  of 
Hercules,  PoUus,  Hector,  and  other  warriors  have  been 
represented  with  ears  having  this  typical  deformity  of 
ancient  contestants.* 

The  ancient  custom  of  boxing  has  been  continued  by 
the  Anglo-Saxon  race,  especially  in  Great  Britain,  where 
for  a  long  time  past  it  has  been  encouraged  as  a  national ' 
amusement  and  has  a  literature  of  its  own.  During  this 
period  of  time,  however,  the  unprotected  fist  has  been 
employed  in  combat,  and  the  occurrence  of  the  more 
serious  aural  injuries  has  in  consequence  diminished. 
Pugilism  has  now  everywhere  fallen  into  disrepute,  and 
its  votaries  are  principally  confined  to  low  resorts, 
where  the  boxers  enter  the  lists  with  gloved  fists  and  go 
through  the  forms  of  a  **  mill  "  for  the  amusement  of  the 
audience.  Even  here,  however,  we  find  that  some  vig- 
orous blows  about  the  head  are  demanded,  and  the  ear 
is  frequently  struck,  especially  in  "cross  counter,"  in 
which  the  left  ear  sufiers  most.  The  frequent  pounding 
of  the  left  auricle  in  this  manner  often  gives  rise  to 
othaematoma.  A  very  considerable  number  of  persons 
are  at  present  engaged  in  this  occupation  for  a  livelihood, 
and  most  of  them  have  characteristically  deformed  auri- 
cles. 

The  tendency  to  violent  contests  has  shown  itself  in 
other  pastimes  where  the  ear  does  not  always  escape 
injury  ;  thus  Farquharson  '  describes  several  cases  of  the 
disease  under  consideration,  coming  on  suddenly,  with 
oval  swelling  of  the  auricle,  as  a  consequence  of  playing 
the  game  of  foot-ball  at  Rugby,  where  there  is  much 
forcible  butting  with  the  head  in  "  tight  scrimmage." 

*^ Idiopathic''  othcematoma, — The  first  description  of 
othaematoma,  in  which  mental  and  other  nervous  dis- 

i  Vide  Gudden :  Haematic  Swelling  of  Ae  Ears  of  the  Insane.  Allg.  ZetL  ffir 
Psychlatrie,  Bd.  xvii.  Med.  Critic,  January,  x86i.  Banking's  Absi.,  vol  L,  p. 
43.  i86z. 

s  British  Medical  Journal,  voL  ii.,  p.  59,  1873. 


THE  MEDICAL  RECORD. 


[July  5,  i884* 


turbances  play  so  important  a  part,  was,  I  believe  pub- 
lished fifty  years  ago  by  Dr.  Frederick  Bird,*  then 
connected  with  the  asylum  at  Sieburg.  Bird  gave  a 
very  good  account  of  six  cases  coming  under  his  ob- 
servation, and  drew  attention  to  the  intimate  relations  of 
the  disease  to  insanity.  The  suggestions  thrown  out  by 
Bird  finally  received  the  attention  of  other  writers  ;  M. 
Ferris,  a  Frenchman,  gave  the  subject  his  attention  in 
1838,  and  ten  years  later  (1848)  the  valuable  essay  on 
the  subject  by  Franz  Fischer  *  was  written.  The  obser- 
vations of  alienists  were  naturally  limited  to  the  occur- 
rence of  the  disease  in  insane  persons ;  in  1852,  how- 
ever, an  Englishman,  Mr.  S.  Ozier  Ward,  drew  attention 
to^the  liability  of  the  mentally  sane  to  the  trouble." 

Numerous  contributions  have  been  made  to  the  liter- 
ature of  the  subject  during  the  past  thirty  years.  In 
1858  an  interesting  paper  was  published  by  Stiff,  "  On 
Simple  Sanguineous  Cyst  of  the  Ear  in  Lunatics,*'*  and 
in  1859  the  distinguished}  labors  of  M.  A.  Foville  were 
made  known.* 

It  will  be  found  on  consulting  the  "  Index  Catalogue 
of  the  Library  of  the  Surgeon-General's  Office  "  •  that, 
although  incomplete  as  yet  in  respect  to  this  subject,  fif- 
teen monographs  and  forty-six  journal  articles  and  other 
papers  pertaining  to  othaematoma  were  published  between 
the  years  1848  and  1879  by  German,  English,  Italian, 
and  American  authors. 

When  it  became  known  that  mentally  sound  persons 
were  obnoxious  to  the  affection  otologists  soon  gave  the 
subject  attention.  Wilde  ^  regarded  it,  however,  as  "  a 
rare  form  of  disease  in  man,"  and  classified  it  among  tu- 
mors of  the  auricle.  The  case  cited  by  him,  with  clini- 
cal history  and  illustrative  wood-cut,  portrays  a  well- 
marked  instance  of  the  trouble  in  a  mentally  sane  person. 

Recognizing  the  similarity  of  his  own  case  to  the  dis- 
ease described  by  Bird  as  occurring  in  the  insane,  but 
having  no  experience  in  the  latter  affection  himself,  he 
made  inquiries  among  a  number  of  medical  friends  con- 
nected with  lunatic  asylums;  from  their  statements, 
which,  however,  "varied  as  to  its  existence  and  cause," 
he  considered  that  it  was  established  that  the  disease  af- 
fected a  particular  class  of  the  community.  Toynbee  " 
afterward  described  the  affection  more  fully  than  Wilde 
had  done,  and  while  regarding  it  as  most  generally  con- 
fined to  the  insane,  he  himself  had  seen  a  case  in  a 
boxer,  due  to  a  blow  upon  the  car. 

ETIOLOGY  OF   OTHAEMATOMA. 

Of  purely  traumatic  othaematoma  no  mention  need  be 
made  here,  but  in  regard  to  the  origin  of  the  so-called 
idiopathic  variety  there  has  been  much  difference  of 
opinion.*  Bird  was  at  a  loss  to  account  for  its  origin, 
never  having  traced  it  to  outward  injury,  but  in  five  of  his 
six  cases  it  is  noted  that  there  was  active  congestion  of 
the  head.  Subsequently,  Franz  Fischer  and  others  pur- 
sued the  subject  further  and  determined  that  the  causes 
must  ultimately  be  sought  in  pathological  states  of  the 
nervous  system. 

One  cannot  witness  the  intense  congestion  of  the 
ears,   sometimes  accompanying   great   cerebral    excite- 

'  Upon  a  Curious  Sort  of  Inflammation  of  the  Outer  Ear  Occuiring  in  Insane 
Patients.  Frederick  Bird.  Graefe's  and  Waltlier's  Journal,  B.  19,  p.  361.  See 
Abs.  M.  Ch.  Rev.,  vol.  xxiv.,  p.  aoi,  1834. 

*  Die  Ohrblutgeschwulst  der  Seeleneestdrten  nebst  einer  Blobachtung  derKoph- 
Uutgeschwulsc  bei  einem  solchen  Kranken.  AUg.  Ztschr.  f.  Psychiat.,  etc.,  BerL, 
1&481  V.  i.    Also  Dr.  Arlidge's  translation,  Asylum  Journal,  1854,  pp.  45-107. 

'  Medical  Times  and  Gazette,  voL  ii.,  p.  295,  1852. 

*  B.  and  F.  Med.  Chir.  Rev.,  voL  xxi..  pp.  169-174.    Am.  Ed.,  1858. 

*  Recherches  sur  les  tumeures  sanguines  du  pavUlion  de  Toreillc  chez  ali^n^s. 
Ann.  M^d.-psych.,  Par.,  1859,  3.  S.,  v.  390-408.  Also :  Gaz.  hebd.  de  m^d., 
PV'f  i859«  vi.  450,  460.  Also :  transl.  Am^  J.  Insan.,  Utica,  N.  Y.,  1859-60, 
zvi.,  184-aoo.  Vide  also,  H^matdme  du  pavillion  de  I'oreille  chez  un  ali^n6. 
Union  m^d.  de  la  Seine-inf..  Rouen,  1877,  xvi.,  24,  37. 

*  VoL  i..  Government  Printing  Office,  Washington,  x88o. 
T  Diseases  of  the  Ksur.     Phila.,  1853. 

•Ibid.    Phila.,  i860. 

*  The  writer's  own  experience  in  othaematoma  having  been  limited  to  cases  oc> 
curring  in  the  mentally  sane,  it  was  deemed  advisable  to  observe  the  disease  in 
the  insane.  Ample  facilities  for  this  were  kindly  afforded  by  Dr.  T.  M.  Franklin, 
Medical  Superintendent  of  the  New  York  City  Lunatic  Asylum  (for  females), 
BlackwelPs  Island,  and  by  Dr.  A.  E.  MacDonald,  Medical  Superintendent  of  the 
New  York  City  Asylum  for  the  Insane  (males),  Ward's  Island.  To  Assistant 
Superintendents  Dent  and  Troutman,  and  other  members  of  the  staff  of  these  insti- 
tutions, the  author's  acknowledgments  are  hereby  extended  for  courteous  atten* 


ment  in  the  insane,  without  belief  in  the  possibility 
of  spontaneous  extravasation  of  blood  taking  place  be- 
neath the  perichondrium  ;  and  it  is  probable  that  where 
tissue  changes,  to  be  immediately  referred  to,  have  al- 
ready taken  place  in  the  cartilage  and  perichondrium 
othaematoma  may  sometimes  thus  occur.  These  nutritive 
changes  in  the  auricle,  believed  to  pave  the  way  to 
extravasation,  so  to  speak,  will  first  demand  our  atten- 
tion. They  seem  to  be  mainly  brought  about  through 
the  agency  of  the  nervous  system,  although  some  authori- 
ties lay  much  stress  on  the  influence  of  blood  dyscrasias 
in  producing  changes  in  the  blood-vessels  of  the  part. 
The  weight  of  evidence,  however,  leads  to  the  conclusion 
that  they  most  frequently  depend  on  a  morbid  state  of 
the  brain,  especially  on  congestion  of  the  organ.  Func- 
tional disturbance  of  the  brain,  or  of  the  cerebrospinal 
centre,  giving  rise  to  disorder  of  the  cervical  sympathetic, 
may,  by  reason  of  the  dominance  thus  exercised  on  the 
vessel  regulating  nerves  distributed  to  both  intercranial 
ganglia  and  the  auricle,  set  up  hyperaemia  in  the  former, 
and  vascular  changes  in  the  latter.*  When  othaematoma 
occurs  in  the  course  of  general  paralysis,  it  would 
seem  that  aural  congestion  took  place  in  consequence  of 
general  degeneration  of  the  sympathetic ;  and  it  has 
been  suggested  that  in  inflammation  of  the  brain  the 
aural  disease  becomes  advantageous  to  the  patient,  since 
the  hemorrhage  is  thus  spent  upon  the  posterior  auriculars, 
coming  from  the  middle  meningeal.' 

But  while  centric  morbid  conditions  are  justly  regarded 
as  of  greatest  importance,  other  impressions,  propagated 
by  morbid  processes  in  other  organs  through  the  sympa- 
thetic system,  are  worthy  of  consideration ;  thus  in  the 
examination  of  insane  subjects  having  this  affection,  the 
almost  universal  prevalence  of  nasal  catarrhs,  diseased 
teeth,  and  in  the  female  of  uterine  disease,  is  notable,  and 
it  is  well  known  that  the  irritation  due  to  these  influences 
is  transmitted  through  the  nerves,  and  may  not  only  ex- 
asperate cerebral  disease  itself,  but  is  liable  to  also  affect 
the  organ  of  hearing. 

The  predisponents  believed  to  have  an  important  re- 
lation to  othaematoma  require  consideration  somewhat  in 
detail : 

Agf.  —  Othaematoma  seldom  occurs  before  adoles- 
cence ;  in  regard  to  its  appearance  in  the  insane,  it  may 
be  said  that  insanity  is  not  obnoxious  to  youth,  nor  is 
degeneration  of  the  cartilage  liable  to  occur  at  this  early 
age.  Cases  of  contusion  of  the  auricle  are  not  frequently 
met  with  in  children,  but  doubtlessly  may  occur  at  any 
age.  Of  the  numerous  cases  reported  as  occurring  in 
extreme  youth,  many  of  them  were  probably  incorrectly 
diagnosed.  Langenbeck  reports  a  case  occurring  in  a 
girl  twelve  years  of  age,  who  was  said  to  be  wild.  Blau  * 
describes  a  case  observed  in  a  gymnast,  aged  fifteen 
years,  where  there  was  no  pschyco-  nor  neuropathic  family 
history.  The  case  had,  it  is  said,  no  history  of  trauma, 
but  it  is  signiflcant  that  otorrhoea  existed.  Schwartze 
has  seen  a  case  in  a  child  fourteen  years  of  age,  and 
Julius  Erhard  *  speaks  of  cases  arising  in  nurslings  from 
rough  handling  or  injury,  causes  from  which  the  writer 
has  never  seen  the  affection  arise.  If  the  disease  ever 
exists  in  young  children,  its  occurrence  seems  to  be 
quite  exceptional.  I  have  myself  never  seen  such  a  case. 
The  disease,  moreover,  has  not  been  to  my  knowledge 
ever  reported  in  extreme  old  age,  which  would  seem  to 
confirm  the  view  that  degeneration  in  structure  alone  is 
not  a  sufficient  cause,  but  that  its  occurrence  must  be 
looked  for  in  the  active  period  between  adolescence  and 
the  decline  of  life. 

Insanity. — All  forms  of  mental  disease  seem  to  be 
predisposing,  but  the  conditions  most  favorable  to 
othaematoma  are  present  in  acute  dementia  where  long- 
existing  vaso-motor  disturbances  are  followed  by  parox- 
ysms of  excitement* 

>  Vide  Robertson,  Glasgow  M.  J.,  voL  viL,  July,  1875. 

3  Bonnet :   Annales  Medico-Psychologiquet,  1877.    A.  J.  O.,  vtrf.  L,  p.  68. 

•  Arch.  f.  Ohrenheilk..  B.  xix.,  Hft.  4,  pp.  203,  904. 

*  VortrSge  iiber^der  Krankheiten  der  Onres,  p.  132.    Leiprig,  1875. 


July  5,  1884.] 


THE  MEDICAL  RECORD. 


When  the  trouble  occurs  in  the  mentally  sound,  pre- 
ceded bj  slight  contusion,  cerebral  or  other  nervous 
disturbance  has  most  likely  existed,  giving  rise  to  trophic 
changes  in  the  affected  part.  A  tendency  to  insanity  in 
such  cases,  however,  is  by  no  means  always  to  be*  sus- 
pected. 

Intemperance, — Intemperance  in  the  use  of  alcoholic 
stimulants  has  a  strong  predisposing  influence ;  I  have 
repeatedly  witnessed  this  in  my  own  practice. 

Cachexia. — A  dyscrasia  commonly  attends  cerebral 
disturbances  in  both  insane  and  intemperate  persons, 
and  although  othaematoma  by  no  means  always  appears 
in  such  subjects  when  the  bodily  health  is  most  impaired, 
yet  must  we  not  entirely  ignore  a  perversion  of  general 
nutrition,  since  this  state  may  be  in  some  degree  predis- 
posing. The  scorbutic  or  rheumic  diathesis  may  thus 
tend  to  impair  the  texture  of  the  coats  and  laceration  of 
the  blood-vessels  of  the  cartilage  and  perichondrium, 
when  passive  hemorrhages  would  more  realdily  take  place 
under  undue  excitement.  Thus  Dr.  Wallace,*  super- 
intending physician  of  the  Insane  Asylum  at  New  Rup- 
pen,  assumes  a  cachectic  condition  in  conjunction  with 
trauma  as  composing  the  etiological  factors  in  othaema- 
toma.. 

Sex. — ^Writers  are  generally  in  accord  respecting  the 
greater  frequency  of  othaematoma  in  the  male.  Mr. 
Nicol,"  who  examined  the  ears  of  a  considerable  number 
of  the  inmates  of  the  Sussex  Asylum,  found  in  24  of  them 
more  or  less  deformity  of  the  auricle,  in  several  of  them 
the  disease  being  in  progress.  Of  the  700  patients  in  the 
institution  two  women  only  were  affected.  Of  the  249 
asylum  patients  examined  by  Stiff— viz. :  124  men  and  125 
women — he  found  the  cartilage  of  the  ear  more  or  less 
thickened  inn?,  probably  the  results  of  othaematoma; 
of  these  12  were  males  and  5  were  females.  In  the  six 
cases  reported  by  Dr.  Bird,'  all  of  them  were  females. 

Lennox  Browne  *  examined  1,424  cases  in  the  West 
Riding  Asylum,  707  of  whom  were  males,  and  717  were 
females.  He  found  that  of  the  32  patients  affected  24 
were  males  and  8  were  females,  making  3.39  per  cent,  of 
the  males  and  i.ii  per  cent,  of  the  femsdes  affected — an 
average  of  2.24  per  cent.  M.  Foville,  in  alluding  to 
this  subject,  says  the  affection  occurs  most  frequently  in 
males.  Hun  *  reports  24  cases  of  the  disease,  23  of  them 
being  males  and  one  of  them  a  female.  The  writer  him- 
self found  in  the  statistics  kindly  furnished  him  by  the 
Blackwell's  and  Ward's  Island  institutions  for  the  insane, 
that  among  1,309  females,  16  cases  of  othaematoma  were 
found,  while  in  1,269  males  14  cases  were  found,  this 
inclusive  of  ears  previously  affected,  as  shown  by  deform- 
ity of  the  auricle,  and  those  in  progress  at  the  time  the 
examinations  were  made.  This  shows  a  percentage  of 
1.14  in  females,  and  i.io  in  males.  It  will  thus  be  seen 
that  the  greater  number  of  cases  occurred  among  fe- 
males. In  the  opinion  of  some  alienists  female  lunatics 
are  more  violent  than  males,  and  the  observations  of  Dr. 
Backe,  of  the  Asylum  at  London,  Canada,  would  seem 
to  verify  such  a  belief.  In  a  recent  report,  in  referring  to 
the  restraint  required  in  an  average  population  of  372 
men  and  394  women,  he  says  that  25  men  were  restrained 
and  secluded  4,079  hours,  and  68  women  20,324  hours. 
The  reporter  offers  no  explanation  for  this,  but  states 
that  on  the  whole  females  are  more  unmanageable  than 
males. 

Women  are  said  to  enjoy  considerable  immunity  from 
the  general  paralysis  of  the  insane,  and  consequently  to 
€scape  the  frequent  paroxysms  of  excitement  which  char- 
acterize this  phase  of  mental  disease.  On  the  other 
hand,  women  are  subject  to  a  monthly  aggravation  of 
symptoms  during  the  menstrual  period,  since  the  men- 


;eben  von  dem  Veretn  fllr  Heilkunde  in  Preussen,  1844. 
Rev.,  No.  xci.. 


*  Med.  Zeituae,  herausgcffcben  von  dem  Veretn  fllr  Heilkunde  11 
No.  3a,  p.  147.  Ibid.,  t84S,  No.  45,  p.  an.    Obs,  by  Dr.  Rupp. 

«  OihaemattMiia,  or  the  Asylum  £ar.     B.  and  F.  Med.  Chir. 
Jialy,  1870. 
'LocdL 

*  Oduematoaia,  or  the  Insane  Ear.    West  Riding  Lunatic  Asylum  Reports, 
•oL  ▼.,  p.  149.     1875. 

*  Hannamma  Auris.    A.  J.  I.,  July,  1870.    Reprint 


tally  sane  even  are  more  irascible  [and  nervous  at  this 
time. 

The  treatment  of  female  lunatics,  moreover,  is  more 
gentle  than  that  of  males,  since  their  attendants  are 
usually  of  their  own  sex,  and  less  liable  than  male  nurses 
to  injure  the  ear  in  handling  violent  and  idiotic  patients. 
The  ears  of  female  lunatics  are  somewhat  protected  by 
their  hair  and  head-dressings. 

Traumatic  agencies, — In  the  mentally  sane  the  affec- 
tion is  most  commonly  met  with  among  prize-fighters, 
gymnasts,  persons  given  to  violent  sports,  and  among 
drunken  and  disorderly  persons,  where  blows  and  falls 
are  frequent 

As  regards  the  insane  there  has  existed  much  diversity 
among  writers  as  to  the  cause.  M.  Bouteille,  who  does 
not  absolutely  reject  the  influence  of  predisposing  causes, 
believes  that  othasmatoma  never  appears  without  vio- 
lence to  the  auricle,  and,  in  alluding  to  an  epidemic  of 
othaematoma  which  occurred  at  Lyons  in  1879,  states 
that  the  trouble  disappeared  by  simply  changing  attend- 
ants.* But  it  is  believed  that  the  ear  is  now  less  fre- 
quently injured  by  violence  than  fonnerly,  since  mechan- 
ical restraints  are  less  in  vogue,  and  an  amelioration  in 
the  general  management  of  the  insane  has  gradually 
taken  place.  Not  long  ago  it  was  not  unusual  for  at- 
tendants to  lead  resisting  patients  by  the  ear,  and  other* 
wise  maltreat  the  organ. 

In  some  of  the  institutions  for  the  insane  where  the 
writer  has  made  inquiries  concerning  the  prevalence  of 
othaematoma  it  would  seem  to  be  of  infrequent  occur- 
rence ;  in  one  asylum  a  case  had  not  been  observed  in 
"  three  or  four  years,"  and  in  respect  to  this  matter  in 
another  institution  the  superintendent  writes  that  the  case 
books  show  that  the  "  phenomenon  has  been  regarded  as 
a  curious  incident  worthy  of  mention,  but  without  suf- 
ficient importance  in  the  history  of  the  insane  individ- 
ual to  merit  description." 

From  a  careful  study  of  the  subject  the  author  has 
come  to  believe  that  othaematoma  is  almost  always  due 
to  violence  inflicted  upon  the  auricle.  Asylum  super- 
intendents, however,  have  been  on  the  whole,  perhaps, 
rather  disposed  to  undervalue  the  importance  of  mechan- 
ical causes,  since  it  might  be  construed  to  imply  undue 
restraint  or  rudeness  in  the  management  of  their  patients. 
It  is  true  that  the  trouble  does  not  always  supervene 
during  paroxysms  of  violence,  but  it  is  difficult  or  im- 
possible even  to  trace  physical  injury  in  all  cases,  or  to 
show  per  contra  that  violent  patients  have  not  injured 
themselves.  Othaematoma  is  of  quite  common  occur- 
rence among  those  who  give  exhibitions  of  sparring  and 
contuse  the  auricles  by  frequent  blows  with  the  gloved 
hand,  and  lunatics  themselves  injure  their  ears  in  like 
manner  by  self-inflicted  blows.  The  extent  to  which  this 
is  carried  by  these  unfortunate  people,  whose  ears  are,  as 
a  matter  of  fact,  much  less  sensitive  than  normal,  is  much 
greater  than  would  seem  possible  to  any  one  unfamiliar 
with  their  habits.  It  is  not  uncommon  for  any  one  to 
strike  with  the  fist  upon  a  region  of  the  body  where  a 
morbid  process  gives  rise  to  slight  pain,  and  I  have  seen 
sane  persons  pull  and  rub  the  auricle  violently  under  cer- 
tain conditions.  The  insane  carry  this  much  farther, 
especially  when  under  excitement.  One  should  not  lose 
sight  of  the  fact  that  the  insane  are  liable  to  experience 
much  discomfort  in  the  ears  from  diseases  of  the  organ, 
to  many  of  which  they  are  particularly  subject,  but 
mental  disturbances  from  delusions  and  hallucinations 
are  frequently  so  associated  with  tinnitus  aurium  and 
autophonia  that  the  patient's  attention  is  continually 
drawn  to  the  ear.  They  have  delusions  respecting  the 
presence  of  persons  and  things  in  the  head,  and  concerning 
fancied  attempts  of  "  evil  spirits  *'  to  gain  admission  there- 
to ;  they  are  in  constant  dread  when  awake  because  of  the 
abusive  and  threatening  language  which  they  imagine  to 
be  spoken  into  the  ears.  Frequently  the  patient's  voice  be- 

*  Annales  M^dico-PsychoIogiques»  Juillet,  1878.    Abst.  A.  J.  O..  vol.  L,  p.  69.I 


THE  MEDICAL  RECORD. 


[July  5>  1884. 


comes  autophonous,  when  the  ears  and  head  seem  "  empty  " 
or  "  cavernous  ;*'  it  then  becomes  yet  more  difficult  for 
the  patient  to  not  imagine  or  believe  that  abominable 
and  dangerous  occupants  have  taken  possession  of  the 
disordered  and  void  dormitory  of  the  mind.  Autopho- 
nia,  which  is  an  expression  intended  here  to  embrace  the 
various  forms  of  tinnitus  as  well  as  autophonous  vocal 
and  respiratory  sounds,  gives  rise  to  hallucinations  in 
mentally  sane  subjects  even,  especially  in  the  aged  and 
feeble. 

Worthy  of  mention  in  this  connection  is  the  distressing 
itching  and  burning  sometimes  set  up  in  the  ear  in  neu- 
rotic subjects,  relief  from  which  is  sought  by  constantly 
pulling,  pounding,  rubbing,  and  pinching  the  external 
parts.  I  have  known  sane  persons  to  endeavor  to  get 
some  relief  from  the  torture  of  pruritis  of  the  ear  by  treat- 
ing the  organ  with  much  violence ;  a  lady  under  my  care 
at  the  present  time  often  finds  herself  involuntarily  scratch- 
ing the  auricle  and  temple  on  account  of  "  creeping  sen- 
sations" in  the  ear,  and  another  patient,  a  clergyman,  has 
the  habit  of  thrusting  a  large  pin  deep  down  into  the 
external  auditory  canal  to  scratch  the  parts ;  he  also  rubs 
the  auricle  at  times  until  it  becomes  intensely  injected. 

Lunatics  often  thrust  objects  like  wool,  rags,  etc.,  into 
the  external  auditory  canal  to  get  rid  of  disagreeable 
noises  in  the  ears  and  head.  The  organ  is  frequently  in- 
jured in  this  way  ;  I  have,  for  example,  seen  a  case  where 
much  damage  was  inflicted  by  thrusting  the  rough  end  of 
a  china  doll's  leg  into  the  ear,  and  in  another  instance,  a 
large  abscess  was  produced  on  the  inner  surface  of  the 
auricle  by  rubbing  and  contusing  it  with  a  stone.  In 
some  instances,  the  insane  strike  the  head  against  some 
object  with  great  violence,  the  injuries  thus  produced 
leaving  the  auricles  abraded  and  scratched ;  others  thrust 
their  fore-fingers  into  the  ears  and  furiously  shake  and 
pull  the  organs — in  one  case  seen  a  papillary  growth  was 
developed  at  the  entrance  of  the  external  auditory  canal 
in  consequence,  and  the  auricles  were  greatly  enlarged. 

It  will  thus  be  seen  that  insane  persons  very  frequently 
have  a  fancy  that  the  organ  of  hearing  constitutes  the 
portal  of  the  mind,  and  we  need  not  wonder,  therefore, 
that  it  is  so  firequently  assailed. 

Among  other  numerous  causes  may  also  be  enumerated 
the  violent  movements  of  certain  insane  persons  when 
in  bed ;  their  pillows,  frequently  consisting  of  materials  no 
softer  than  straw  or  husks,  are  liable  to  injure  their  ears, 
especially  during  their  struggles  under  restraint.  Again, 
when  forcibly  fed,  while  the  head  k  held  in  the  strong 
embrace  of  the  nurse,  the  ears  are  liable  to  injury.  In- 
sane paralytics,  if  allowed  to  remain  too  long  without 
change  in  position,  may  sufifer  from  an  interference  in 
the  process  of  nutrition  on  account  of  the  undue  pressure 
upon  the  ear,  and  rude  handling  of  the  head,  as  often 
practised  by  attendants,  may  likewise  injure  the  auricle. 
Sloughing  of  the  auricle  from  long-continued  pressure  in 
lying  upon  the  organ  in  cases  of  fever  not  unfrequently 
occurs  in  the  mentally  sane.' 

Othaematoma  has  been  described  by  writers  on  the  ear 
as  due  to  bites,  bums,  dentition,  etc.  Urbantschitz  '  re- 
ports the  case  of  a  woman  where  both  ears  were  believed 
to  be  thus  a£fected  by  a  bite  of  some  kind,  and  Kipp ' 
reports  the  case  of  a  child,  considered  to  be  thus  afifected, 
where  both  auricles  were  injured  by  a  burn.  Cases  sup- 
posed to  be  due  to  dentition  are  related  by  Frank,^  who 
says,  '*  During  dentition,  this  condition  is  often  observed 
to  occur,  usually  in  scrofulous  subjects."  The  writer, 
whose  experience  in  this  disease  has  been  considerable, 
has  never  seen  othsematoma  arise  from  any  of  these 
causes,  and  it  seems  probable  that  in  some  of  them  at 
least  phlegmonous  inflammation  only  may  have  been 
present. 

In  reviewing  the  causes  of  othsematoma,  it  would  seem 
that  it  has  no  special  preference  for  either  sex  or  for  any 
one  form  of  insanity,  and  that  it  may  be  produced  in  the 

>  Williams'  Treatise  on  the  Ear,  p.  108.    J^ndon.  1840.      >  I>ehrbuch,  p.  89. 
*  Trans.  A.  O.  Soc.,  1867,  p.  79.  *  Ohrenkranlcheiten,  p.  348. 


mentally  sane  by  contusion  of  the  auricle.  That  it 
depends  almost  exclusively  upon  traumatic  influences  in 
all  cases  seems  a  warrantable  deduction. 

Occurrence, — The  more  frequent  occurrence  of  othae- 
matoma  in  the  left  ear  has  been  the  subject  of  much 
speculation.  Stiff*  drew  attention  to  this  preference;  he 
found  that  in  1 7  cases  the  left  ear  was  aflected  in  6  cases, 
the  right  ear  in  4,  and  both  ears  in  7.  Of  the  24  cases 
reported  by  Lennox  Browne,  the  left  ear  was  affected  in 
19,  the  right  ear  in  2,  and  both  ears  in  11  ;  when  both 
ears  were  aff"ected  the  left  was  first  attacked.  The  ex- 
perience of  some  observers  has  been  the  reverse  of  the 
authorities  above  quoted,  thus  Hun^  in  his  24  cases 
found  the  right  ear  to  be  the  seat  of  the  trouble  in  9 
cases,  the  left  in  5,  both  ears  in  9,  and  in  one  the  history 
was  incomplete  in  this  regard.  In  the  cases  where  bodi 
ears  were  affected  it  is  not  stated  which  side  was  first  at- 
tacked. 

The  greater  frequency  of  occurrence  in  the  left  ear 
does  not  seem  to  hold  good  in  the  mentally  sane  with  the 
exception  of  pugilists,  who  more  frequently  contuse  the 
left  auricle. 

Vaiious  theories  have  been  advanced  in  explanation  of 
this  peculiar  manifestation.  Thus  it  has  been  suggested 
that  the  near  position  of  the  left  carotid  artery  to  the 
heart  affords  a  more  direct  blood  supply  to  the  left  ear, 
and  that,  furthermore,  the  left  pinna  is  oftenest  affected 
because  pulling  or  striking  the  organ  is  more  liable  to 
be  done  with  the  right  hand,  the  left  ear  receiving  the  in- 
jury. The  left  ear,  it  is  said,  is  also  more  lia)>le  to  in- 
jury than  the  right  in  forcible  feeding,  since  in  holding 
the  patient  the  arm  of  the  nurse  usually  presses  it  with 
more  or  less  violence  against  the  head." 

An  explanation  of  the  greater  frequency  of  left-sided 
othsematoma,  however,  must  be  sought  in  some  other  di- 
rection, since  the  above  apply  to  mechanical  agencies 
only.     It  seems  probable   that  some  very  intransient 
influence   must  exist  to  cause  the  trouble    to   appear 
so  frequently   on   the  left   side,    and    could    this    be 
discovered,  much  light   would  doubtlessly   be    thrown 
not    only  on   the   etiology  of   othsematoma,    but    also 
on  other  aural  diseases.     It  has  occurred  to  the  writer 
that  probably  some  vaso-motor  influence  might  be  found 
to  lie  at  the  bottom  of  the  difficulty.     It  is  a  fact  that 
unilateral  sweating  about  the  head  is  not  an  uncommon 
occurrence  ;  and,  moreover,  in  bilateral  chronic  catarrh 
the  left  ear  is  seemingly  much   more  rapidly  invaded 
than  the  right  in  a  notable  number  of  instances — a  con- 
dition due,  in  all  probability,  to  some  vaso-motor  disturb- 
ance  whereby  the   nutritive  process  is  interfered  with 
much  more  on  the  left  than  on  the  right  side.     While 
this  agency  may  be  found  to  lie  in  some  cerebral  or  cere- 
bro-spinal  condition,  there  exists  a  prominent  irregularity 
in  the  distribution  of  the  sympathetic  nerves  which  it 
occurs  to  the  writer  might  bring  about  such  a  result.     Ref- 
erence is  had  to  the  peculiar  arrangement  of  the  nerves 
extending  upward  from  the  cardiac  plexus  to  the  two 
sides  of  the  head.     According  to  anatomists  there  is  to 
be  found  here  an  important  irregularity.     Thus,  while  an 
unvarying  connection  is  maintained  with  the  right  side 
through  the  superior  cervical  ganglion,  a  comparatively 
imperfect  and  varying  connection  exists  on  the  left  side 
— the  left  superior  cardiac  nerve  and  the  inferior  cardiac 
branch  of  the  pneumogastric  only  occasionally  affording 
communication  between  the  cardiac  plexus  and  the  left 
superior  cervical  ganglion. 

Of  course  other  but  less  direct  communications  exists 
which  bring  the  cardiac  plexus  into  relationship  with  the 
left  ear,  nevertheless  the  asymmetrical  distribution 
above  described  might  be  the  means  of  diminishing  the 
vaso-motor  dominance,  in  respect  to  the  circulation  in 
the  left  ear.  Granting  the  correctness  of  the  hypothesis, 
which,  however,  is  by  no  means  held  to  be  indisputable, 

>  I.0C  cit,  «  Loc.  dt. 

^  *  llie  u-riter*s  attention  was  drawn  to  this  latter  explanation  by  Dr.  Craic  As- 
sistant Surgeon  New  York  Asylum  for  the  Insane. 


July  5,  1884.] 


THE  MEDICAL  RECORD. 


the  disparity  in  the  vascularity  of  the  two  ears  would 
finally  produce  distinguishing  nutritive  changes  in  the 
tissues  of  the  parts — alterations  especially  well  marked  in 
the  tympanic  membranes  in  otitis  medio  catarrhalis  chron- 
ica^ where  the  membrane  of  the  left  tympanum  will  fre- 
quently be  found  to  be  quite  parchment-like  and  lustre- 
less, while  the  right  membrane  is  yet  in  a  fairly  normal 
condition.  It  is  thus  difficult  to  see  why  nutritive  changes 
may  not  affect  the  cartilage  of  the  left  ear  more  fre- 
quently than  the  right,  and  give  rise  to  the  greater  fre- 
quency of  othasmatoma  on  the  left  side. 

Othematoma  is  frequently  bilateral,  very  often  de- 
veloping equally  on  both  sides.  It  may  develop  rapidly 
and  disappear  again  as  rapidly  as  it  came.  This  bilateral 
invasion  is  suggestive  of  centric  nervous  origin. 

Othaematoma  has  been  observed  to  occur  during  preg- 
nancy. Gruber  alludes  to  a  case  which  came  to  his  clinic 
in  the  fourth  month  of  pregnancy. 


YELLOW    FEVER    ON    THE  UNITED   STATES 
STEAMSHIP  PORTSMOUTH.^ 

By  a.  M,  MOORE,  M.D., 

SURCBON   U.   S.   NAVY. 

Endemic  influence, — ^The  only  morbid  influence  of  this 
nature  that  came  under  my  observation  was  that  of  in- 
termittent and  remittent  fevers  at  St.  Thomas,  W.  I. 
These  diseases  prevail  here  every  year,  and  all  the  year 
round.  According  to  the  statistical  report  of  Dr.  Ma- 
gens,  King's  Physician,  for  the  year  1883,  there  were  742 
classified  under  this  head,  out  of  a  total  number  of  dis- 
eases of  all  kinds  of  1,793 — population  estimated  at  15,- 
000.  That  they  were  light,  however,  is  shown  by  the 
£act  that  there  were  only  4  deaths  out  of  this  number, 
the  total  number  o(  deaths  from  all  causes  for  this  period 
being  415.  The  period  of  their  greatest  activity  is  that 
which  covers  the  months  of  October,  November,  and 
December,  the  so-called  rainy  season.  This  term,  it  is 
obvious,  is  merely  relative,  as  abundance  of  rain  falls  at 
all  seasons ;  the  mean  annual  amount  being  46.8  inches. 
This  **'  influence  "  was  felt  on  board  ship  in  Uie  form  of 
mild  intermittents,  two  or  three  cases  of  which  were 
under  daily  treatment  during  a  twelve-days'  sojournment 
of  the  ship  at  that  place,  but  which  promptly  disappeared 
upon  our  departure.  It  is  an  interesting  fact  that  the 
conditions  under  which  these  fevers  exist  here  are  not 
such  as  are  generally  conceded  to  be  required  for  the 
production  of  malarial  diseases.  These  conditions  are 
best  indicated  by  the  names  which  have  been  applied  to 
the  whole  class — '* paludal, **  ''swamp,*'  and ''marsh" 
fevers.  Now,  this  Island  is  a  mass  of  trappean  rock,  de- 
void of  vegetation  except  some  species  of  cactus  and  a 
few  small  and  hardy  shrubs,  and  trees  that  can  scarcely  be 
dignified  with  the  name.  There  is  an  entire  absence  of 
stagnant  water,  or  even  of  fresh- water  springs  and  streams, 
the  rain  which  falls  running  rapidly  down  the  mountain 
side  into  the  sea.  Again,  malaria  is  rural,  and  not  urban ; 
it  selects  as  its  favorite  habitation  the  fresh-water  fens 
of  the  interior,  and  shuns  salt  water.  But  malarial  fevers 
are  endemic  here,  where  the  conditions  are  of  a  nature 
to  lead  one  to  expect  to  find,  rather,  yellow  fever  !  Does 
not  this  circumstance  suggest  the  possibility  of  intercon- 
vertibility  under  certain  favorable  influences  ?  As  a 
matter  of  fact,  when  an  unacclimated  person  indiscreetly 
exposes  himself  to  the  miasmatic  emanations  here,  he 
may  possibly  be  stricken  mih  yellow  fever. 

Report  of  three  ccues  of  yellow  fever. — In  order  to 
complete  and  illustrate  the  remark  under  the  head 
of  ''Endemic  Influence,"  the  anachronism  is  com- 
mitted of  reporting  with  the  first  quarter  some  cases 
of  the  above-named  disease  which  occurred  during  the 
second.  It  is  believed  that  this  incongruity  in  time 
is  justified  by  the  increased  value,  if  there  be  any,  which 

>  From  the  report  o<  sick  for  the  first  quarter,  1884. 


will  be  thus  obtained  by  placing  in  juxtaposition  re- 
ports so  closely  related  that  one  might  be  taken-  as  a 
sequence  of  the  other.  Whatever  may  be  the  degree 
of  relationship  between  malarial  fevers  and  yellow  fever, 
the  fact  is  potent  that,  at  a  time  when,  according  to  the 
reiterated  assurances  of  the  American  consul  and  king's 
physician,  St.  Thomas  was,  and  had  been  for  four  years, 
entirely  free  from  the  last-mentioned  disease,  this  disease 
was  propagated  from  thence  to  persons  on  board  this 
vessel.  Such  being  the  case,  it  becomes  a  serious  ques- 
tion whether  it  is  ever  judicious,  from  a  sanitary  point  of 
view,  to  send  ships  of  this  kind,  with  a  crew  composed 
largely  of  boys,  who  might  become  easily  demoralized,  to 
this  port.  In  this  connection  it  may  be  proper  to  state 
that  every  precaution  was  taken  at  this  place  to  preserve 
the  health  of  the  ship's  company  short  of  absolute  de- 
privation of  liberty,  which,  indeed,  was  restricted  to  four 
hours  during  daylight.  In  view  of  the  best  information 
obtainable  as  to  its  good  sanitary  condition,  this  limited 
liberty  was  not  considered  injudicious.  It  is  proper  also 
to  observe  that  at  the  military  hospital  visited  there  was 
no  case  that  resembled  in  the  remotest  degree  yellow 
fever.  In  addition  to  the  three  cases  reported,  there  was 
another  of  a  suspicious  nature,  which  appeared  on  the 
14th,  and  which  was  isolated  with  the  rest,  but  as  the  sub- 
ject of  it,  a  marine,  had  not  been  ashore  in  St.  Thomas, 
it  is  not  included  in  the  report. 

Case  I. — The  ship  sailed  from  St.  Thomas,  bound  for 
Hampton  Roads,  Va.,  early  on  the  morning  of  April  5th, 
and,  as  before  stated,  the  few  cases  of  febriculas  disap- 
peared very  soon  thereafter.    About  3.30  p.m.  of  the  9th, 

four  days  out.  Commander  W.  C.  W ,  who  was  last  on 

shore  for  about  four  hours  on  the  afternoon  of  the  4th, 
was  taken  sick — ^his  illness  being  initiated  by  rigors,  fol- 
lowed in  about  an  hour  by  headache  and  fever.  Tem- 
perature at  7  P.M.,  103.5° ;  pulse,  90.  Was  put  to  bed, 
and  0.7  grm.  quinia  administered. 

April  loth. — ^Temperature  at  8  a.m.,  101° ;  pulse, 
90  ;  at  7  P.M.  :  temperature,  102.2° ;  pulse,  7a  ;  vom- 
ited copiously  in  the  morning  a  dark  liquid,  about  the 
color  of  weak  coffee,  repeated  in  smaller  quantity  twice 
during  the  afternoon  ;  vessels  of  conjunctivae  deeply  in- 
jected ;  frontal  headache  and  dizziness ;  pain  in  back, 
"  as  if  it  would  break  in  two  ;  "  skin  of  forehead  hot  to 
the  touch ;  face  flushed  ;  no  epigastric  pain  or  tender- 
ness ;  marked  hebetude ;  complete  anorexia  ;  specific 
gravity  of  urine  1032,  scanty,  dark  colored,  acid,  with  no 
trace  of  albumen. 

April  nth. — ^Temperature  at  8  A.M.,  102,2°;  pulse, 
72  ;  at  7  P.M.:  temperature,  102.9° ;  pulse,  72  ;  urine  al- 
buminous ;  vomiting  of  yellowish- white  matter  at  inter- 
vals ;  is  heavy,  and  sleeps  much. 

April  i2th. — Temperature  at  8  a.m.,  101°;  pulse,  55  ; 
at  7  P.M. :  temperature,  100.9°;  pulse,  47,  weak  and 
compressible  ;  specific  gravity  of  urine  1026,  albuminous 
and  scanty ;  continues  to  vomit  at  intervals  small  quan- 
tity of  whitish  matter ;  no  reciurence  of  "black  vomit** 
since  second  day. 

April  13th. — Temperature  at  8  A.M.,  98.4°;  pulse,  54; 
at  7  P.M.  :  temperature,  99.2° ;  pulse,  56  ;  specific  gravity 
of  urine,  1024,  highly  albuminous ;  several  copious  and 
spontaneous  dejections  of  dark  green  matter ;  heat  of  sur- 
face and  headache  less  intense ;  ferrety  appearance  of 
eyes  disappearing. 

April  14th. — ^Temperature  at  8  A.M.,  99°;  pulse,  56  ; 
at  7  P.M.  :  temperature,  99°  ;  pulse,  58 ;  urine  albuminous, 
acid,  specific  gravity,  1026 ;  headache  and  lumbar  pain 
gone. 

April  15th. — Temperature  at  8  A.M.,  98.5° ;  pulse,  60  ; 
at  7  P.M. :  temperature,  99°  ;  pulse,  60 ;  urine  highly  albu- 
minous, acid,  specific  gravity  1023,  quantity  increasing ; 
great  languor. 

April  i6th. — Temperature  at  8  a.m.,  99° ;  pulse,  58 
and  weak;  at  7  p.m.  :  temperature,  98.5° ;  pulse,  50 ;  al- 
bumen continues  in  undiminished  quantity  in  urine; 
conjunctivae  jaundiced. 


8: 


THE   MEDICAL  RECORD. 


[July  5,  1884. 


April  17th. — Temperature,  normal;  pulse,  54;  urine 
albuminous ;  amount  voided  during  last  twenty-four  hours 
360  C.C.  (12  oz.),  being  the  largest  daily  quantity  during 
the  illness ;  specific  gravity  1024 ;  tinct.  iodinii  shows 
grass-green  reaction  of  biliverdine.  (This  reagent  was 
preferred  to  nitric  acid,  on  account  of  the  confusion  of 
color  produced  by  the  latter  on  precipitated  albumen. 
Pettenkofer's  test  failed  to  reveal  the  presence  of  the 
biliary  substances  proper,  although  great  care  was  taken 
in  its  application — a  specimen  of  urine  being  evaporated 
to  dryness,  the  solid  residue  redissolved  in  alcohol,  and 
a  precipitate  obtained  by  addition  of  ether,  which  was 
redissolved  in  distilled  water,  10  which  the  test  was  ap- 
plied. The  failure  to  obtain  any  evidence  of  their  pres- 
ence may  have  been  due,  however,  to  lack  of  skill  in 
manipulation.)  Skin  and  conjunctivae  profusely  jaundiced. 

April  1 8th. — Temperature  at  8  A.M.,  97.4°  ;  pulse,  47, 
with  more  volume  ;  at  7  p.m.  :  temperature,  98** ;  pulse, 
54 ;  albumen  decreasing  in  urine,  specific  gravity  1025  ; 
amount  voided  during  twenty-four  hours,  620  c.c. — 
marked  increase. 

April  iQth. — Temperature  at  8  a.m.,  97°;  pulse,  47; 
at  7  P.M.:  temperature,  96.6°;  pulse,  48;  quantity  of 
urine,  610  c.c. ;  specific  gravity  1020,  albumen  decreasing 
in  quantity  ;  skin  and  eyes  remain  deeply  jaundiced. 

April  20th. — Temperature  at  8  a.m.,  97.2°  ;  pulse,  54; 
at  7  P.M.  :  temperature,  98°;  pulse,  48 ;  amount  of  urine 
voided  during  past  twenty-four  hours,  720  cc  ;  specific 
gravity  1024,  albumen  entirely  disappeared. 

April  24th. — Since  last  entry  patient  has  improved 
greatly^  and  now  sits  up  the  greater  part  of  the  day ;  like 
Oliver  Twist,  he  *' wants  more'*  to  eat,  and  his  diet  is 
being  cautiously  increased  daily.  The  yellow  tint  of 
skin  and  eyes,  though  still  quite  manifest,  is  daily  pass- 
ing away. 

Case  II. — On  the  morning  of  April  12th,  Justin  P. 
Q- — ,  bugler,  a  native  of  France,  aged  about  forty-two 
years,  reported  sick,  with  a  temperature  in  axilla  of 
1 00. 2°,  violent  headache  with  dizziness,  face  flushed, 
eyes  bright  and  deeply  congested,  lower  eyelids  dark  and 
swollen,  as  if  by  effusion  of  disintegrated  blood  into  sub- 
cutaneous cellular  tissue,  heat  of  skin  marked ;  tongue 
coated  and  is  protruded  with  a  tremulous  motion ;  there 
is  complete  anorexia,  though  no  pain  or  tenderness  of 
epigastrium  or  back  is  apparent.  States  that  he  has 
been  feverish,  with  headache,  for  last  two  days,  which 
makes  the  commencement  of  his  illness  the  loth.  Was 
ashore  in  St.  Thomas  from  morning  of  March  29th  till 
afternoon  of  next  day,  when  he  returned  aboard  "  drunk 
and  dirty." 

April  13th. — ^Temperature,  101°;  pulse,  90;  urine 
straw-colored,  scanty,  acid,  and  free  from  albumen ; 
headache  and  congestion  of  face  and  conjunctivae  con- 
tinue ;  eyes  closed  by  swelling  of  lids,  which  have  a  ten- 
dency to  agglutination  ;  facial  aspect  repulsive ;  odor  of 
breath  musty  and  highly  offensive  ;  anorexia  continues, 
though  no  pain  or  irritability  of  stomach  is  complained  of 

April  14th. — Temperature  at  8  a.m.,  101°;  pulse,  96  ; 
at  7  P.M.:  temperature,  101.8°;  pulse,  98  ;  urine  acid, 
specific  gravity  1028,  no  albumen  ;  face  and  eyelids  con- 
tinue swollen  and  eyes  congested  ;  headache  diminished  ; 
complete  anorexia,  but  no  nausea  or  gastric  disturbance ; 
gums  spongy  and  bleeding. 

April  15th. — Temperature  at  8  A.M.,  100°;  pulse,  78  ; 
at  7  P.M. :  temperature,  101.2®;  pulse,  78  ;  urine  free 
from  albumen ;  swelling  of  face  and  eyelids  subsiding ; 
headache  giving  way  to  soreness  of  scalp. 

April  1 6th. — Temperature  at  8  a.m.,  99.4°;  pulse,  74  ; 
at  7  P.M. :  temperature,  100.4®;  pulse,  78  ;  urine  free 
from  albumen  ;  facial  aspect  improving  ;  head  better. 

April  17th. — Temperature  at  8  a.m.,  98.8°;  pulse,  74  ; 
at  7  P.M.':  temperature,  99.8°;  pulse,  80  ;  no  albumen  in 
urine  ;  eyes  much  clearer  ;  swelling  of  lids  subsided. 

April  1 8th. — Temperature,  normal ;  pulse,  72;  urine 
albuminous^  straw-colored,  acid ;  reports  himself  as  feel- 
ing better. 


April  19th. — Temperature,  normal ;  pulse,  72 ;  albumen 
in  urine  increasing  in  quantity  ;  no  pain  or  sense  of  dis- 
comfort in  epigastrium  or  back  ;  free  alvine  dejections  of 
dark  green  matter — conjunctivae  jaundiced. 

April  2oth. — Temperature  normal,  urine  albuminous, 
eyes  jaundiced, 

April  2 1  St. — Temperature  normal,  urine  continues 
albuminous ;  progressing  favorably. 

April  2 2d. — ^Temperature  normal,  albumen  decreasing 
in  quantity  ;  skin  and  conjunctivae  clearing  up. 

April  23d. — Temperature  normal ;  albumen  disap- 
peared from  urine.  From  this  time  is  dated  the  com- 
mencement of  convalescence.  There  is  no  pain,  and 
patient  complains  of  nothing  but  unsatisfied  hunger. 

Case    III. — George    D.    F ,    third    cabin    boy, 

native  of  England,  eighteen  years  and  four  months  of 
age,  reported  on  forenoon  of  April  13th,  with  following 
symptoms,  viz. :  intense  frontal  headache,  giddiness,  and 
mental  confusion  ;  eyes  bright  and  conjunctivae  deeply 
congested ;  face  flushed  ;  racking  pain  in  shoulder  and 
knee  joints  ;  anorexia,  but  no  nausea  or  epigastric  pain 
or  tenderness,  and  no  lumbar  pain  ;  temperature,  99.2®; 
pulse,  100  ;  states  that  he  has  suffered  from  headache  and 
articular  pains  for  two  days,  hence  the  accession  of  the 
disease  is  fixed  at  the  nth  inst.  Patient  was  ashore  in 
St.  Thomas  from  i  to  8.30  p.m.  on  March  29th,  the  last 
two  hours  of  which  he  spent  sitting  on  the  wharf,  where, 
it  is  to  be  presumed,  miasmatic  emanations  are  the  most 
virulent. 

April  14th. — ^Temperature  at  8  a.m.,  100.2**;  pulse, 
96  ;  at  7  P.M. :  temperature,  102.8°;  pulse,  100  ;  tongue 
(dry  and  bare  last  night),  moist ;  urine  acid,  specific 
gravity  T026,  non-albuminous ;  articular  pains  better, 
otherwise  much  the  same  as  yesterday. 

April  isth. — Temperature  at  8  a.m.,  99°;  pulse,  78 ; 
at  7  P.M. :  temperature,  100.4° ;  head  symptoms,  as  well 
as  articular  trouble,  much  better ;  no  appearance  of 
albumen. 

April  1 6th. — ^Temperature,  99°;  pulse,  76  ;  head  symp- 
toms and  articular  pains  entirely  disappeared ;  anorexia 
persistent ;  eyes  still  congested ;  no  albumen. 

April  17th. — Temperature  at  8  a.m.,  99.8°;  pulse,  80  ; 
at  7  P.M.:  temperature,  98.5°;  pulse,  78;  conjunctivae 
congested;  urine  acid,  straw-colored,  transparent,  and 
non-albuminous  ;  no  pain  or  tenderness  of  epigastrium.  | 

April  i8th. — ^Temperature  at  8  a.m.,  99°;  pulse,  78  ; 
at  7  P.M. :  temperature,  100.2°;  pulse,  78  ;  character  of 
urine  unchanged  ;  eyes  remain  congested  ;  slight  frontal 
headache ;  gums  spongy  and  bleeding  ;  lips  dry  and  en- 
crusted. 

April  19th. — Temperature  at  8  a.m.,  98.6°;  pulse,  76 ; 
at  7  P.M.:  temperature,  98.4°;  pulse,  60;  no  indication  of 
albumen  in  urine;  sponginess  and  bleeding  of  gums 
slightly  improved. 

April  2oth. — ^Temperature  at  8  a.m.,  97.8°;  pulse,  60; 
at  7  P.M. :  temperature,  99°;  pulse,  72  ;  no  albumen  ;  in- 
jection of  vessels  of  conjunctivae  fading  ;  opened  yester- 
day a  large  abscess  over  left  parotid  region. 

April  2 1  St. — ^Temperature  at  8  a.m.,  98°;  pulse,  56  ;  at 
7  P.M. :  temperature,  97.6°  ;  pulse,  60  ;  conjunctivae  less 
congested  ;  trace  of  albumen  in  urine. 

April  22d. — ^Temperature  at  8  a.m.,  97.2°;  pulse,  54; 
at  7  P.M. :  temperature,  98°;  pulse,  48  ;  urine  more 
markedly  albuminous ;  conjunctivae  jaundiced. 

April  23d. — ^Temperature  at  8  a.  m.,  97.4°;  pulse,  48; 
at  7  P.M.:  temperature,  98.2°;  pulse,  60;  albumen  disap- 
pearing from  urine,  which  is  increasing  in  quantity; 
opened  a  small  abscess  in  outer  edge  of  nasal  septum — 
left  side.     Doing  well 

April  24th. — ^I'emperature  normal;  urine  abundant 
and  albumen  disappeared ;  patient  is  pronounced  con- 
valescent— the  chief  symptom  being  hunger. 

The  principles  involved  in  the  treatment  of  these  cases 
consisted  in  rest  of  the  stomach,  and  of  measures  adapted 
to  relieve  renal  congestion  and  to  increase  the  excretion 
and  elimination  of  urine.    In  the  case  of  Captain  W , 


July  5,  1884.] 


THE  MEDICAL  RECORD. 


the  type  o(  the  disease  was  different  from  that  of  Q 

and  F .  In  the  former,  gastric  symptoms  pre- 
dominated and  were  quite  serious  for  the  first  three  or 
foar  days,  while  in  the  two  latter  the  head  symptoms 
were  the  most  important  and  -the  cases  approached 
more  nearly  the  sthenic  type.  It  will  be  observed  that 
in  these  last  cases  the  stomach  was  not  at  any  time 
noticeably  involved  in  the  train  of  morbid  symptoms^  and 
it  was  only  at  a  very  late  date  that  albumen  made  its  ap- 
pearance in  the  urine.     In  the  case  of  Q ,  the  first 

indication  of  its  presence  was  on  the  eighth  day  of  the 
disease,  and  it  had  ceased  to  appear  on  the  thirteenth ; 

with  F it  was  observed  first  on  the  tenth,   and 

had  entirely  disappeared  on  the  thirteenth  day  ;  while 

in  Captain  W *s  case  it  was  found  on  the  third  day,  and 

it  was  not  until  the  eleventh  that  reagents  failed  to  re- 

vttil  its  presence.    Again,  Captain  W was  profoundly 

jaundiced,  while  the  other  two  were  not  at  all  markedly 
so.*  Hence,  while  the  principles  of  treatment  were  the 
same  in  aU,  these  dififerences  in  type  and  symptoms  made 
it  necessaiy   to  vary  the    details.     For  example,   the 

tincture  of  digitalis,  which  was  used  early  with  Q and 

F as  a  cuuretic,  could  not  be  tolerated  by  Captain 

W until  about  the  fifth  day  of  the  disease,  on  account 

of  excessive  gastric  irritability.  In  all,  revulsives  were 
applied  over  the  epigastrium  and  renal  region,  from  the 
inception  of  the  disease  till  the  disappearance  oi  albumen 
from  the  u/ine.  The  agents  used  for  this  purpose,  and 
found  effective,  were  sinapisms  and  tincture  of  iodine. 
Nothing  whatever  in  the  way  of  diet  was  permitted  until 
the  fifth  day  of  the  disease,  when  the  blandest  articles,  as 
wine  jelly,  arrow-root,  etc.,  were  allowed,  and  the  dietary 
cautiously  varied  and  increased  from  that  time.  From 
about  the  eighth  day,  milk  punch  was,  with  appreciably 
good  results,  added  to  the  other  allowance.  After  albu- 
men ceased  te  appear  in  urine,  a  tonic  of  quinia,  iron,  and 
acid,  sulph.  was  substituted  for  the  digitalis.'    Captain 

W was,  of  course,  treated  in  the  cabin,  access  to  which 

was  prohibited  to  all  except  the  surgeon  and  nurse  (a 
man  who  had  had  the  disease,  detailedfor  that  purpose). 
The  other  cases  were  isolated  in  the  sick-bay,  no  one 
being  allowed  to  enter  there  besides  the  surgeon,  apothe- 
cary, and  bay-man.  This  place  was  selected  for  the  pur- 
pose because,  first,  there  was  no  better;  second,  their 
isolation  could  be  accomplished  here  with  the  least 
danger  of  attracting  attention  and  arousing  suspicion,  a 
thi]^  which  it  was  obviously  desirable  to  avoid.  The 
atmos[^ere  oi  the  sick-bay  was  disinfected  daily  by 
difilusion  of  a  saturated  solution  of  carbolic  acid  by  means 
of  the  steam  atomizer. 

The  first  case.  Captain  W ,  occurred  in  latitude 

25.o8*'N.,  with  a  temperature  of  73<>  F. ;  the  last,  F , 

Id  latitude  27.  io°  N.,  with  a  temperature  of  76**  F. 

The  fiavorable  progress  of  these  cases  is  largely  due  to 
the  fact  of  their  not  appearing  until  the  ship  was  well  on 
the  way  to  the  north,  and  to  getting  soon  into  cooler 
weather.  To  the  same  cause  the  ship's  company  are 
undoubtedly  indebted  for  their  immunity  from  further  at- 
tacL  At  noon  of  the  13th  the  ship  had  reached  a  tem- 
perature of  65®  F.,  and  from  that  time  there  was  a  steady 
decline  till  a  temperature  of  about  42  "^  was  attained, 
about  April  23d. 

For  the  first  few  days  after  the  first  case  announced  it- 
self, the  situation,  with  two  hundred  and  sixty-five  human 
bein^  mostly  bovs,  enclosed  in  the  narrow  confines  of 
a  ship,  in  a  tropical  climate,  and  dependent  upon  the 
light  and  capricious  winds  of  the  **  horse  latitudes,"  was 
anything  but  reassuring.  It  was  thought  best  by  the 
sorgeon  and  executive  officer  to  conceal  from  every  one 
the  existence  of  the  disease  in  the  ship.  But  with  these 
tvo  the  anxiety,  while  the  ship  lingered  in  the  region  of 
bi^  temperature,  was  intense,  lest  each  day  might  wit- 


<Ia«nthe  -  .  ,       . 

jfauiit  odor  of  die  breftdi,  poisibiy  due  to  carbonate  of  ammonium,  from  decom* 
I^Mioa  of  retained  nrea. 

'  b  ^  hfgjnning  iIk  contents  of  the  boweb  were  removed  by  an 
■■pen;  lu^h.,  50.00  grm.,  and  water.  | 


tiiere  was  notioad  for  tbe  first  few  days  a  musty  and  peculiarly 
of  ai 

Rofioap^ 


ness  the  accession  of  other  cases  to  the  sick  list,  and 
with  the  dire  consequences  of  an  epidemic  on  the  morale 
of  a  crew  of  this  kind  staring  them  in  the  face.  Then, 
as  suspicion  began  to  be  aroused,  with  its  resulting  de- 
pression, the  task  of  wearing  a  cheerful  mien,  with  an 
apprehensive  mind,  was,  indeed,  a  difficult  one  to  suc- 
cessfully assume.*  ^ 

gr00t:css  0f  Medical  ^cietice. 

■       ■■    ■    ■       ■  f 

Laryngitis  Hemorrhagica. — Dr.  Stepanoff  regards 
this  affection  as  a  distinct  form  of  laryngeal  inflammation, 
arising  from  the  same  causes  as  the  catarrhal  form,  yet 
affecting  females  only.  The  primary  symptoms  are  those 
of  ordinary  laryngitis,  but  after  from  three  to  fourteen 
days,  hemorrhage  occurs.  It  is  sometimes  excited  by 
coughing,  but  may  also  come  on  without  any  noticeable 
cough.  The  amount  of  blood  may  vary  from  half  an 
ounce  to  four  ounces.  There  may  be  one  or  several  at- 
tacks of  hemorrhage,  and  after  they  have  ceased,  the 
symptoms  of  catjirrhal  laryngitis  remain  for  a  longer  time 
than  in  the  common  form.  Suffocative  attacks  occur  but 
seldom.  The  laryngoscopic  picture  differs  firom  that  of 
the  ordinary  variety  only  in  the  presence  of  blood-clots. 
The  intensity  of  the  catarrhal  inflammation  stands  in  no 
relation  to  the  amount  of  hemorrhage.  Blood  comes 
only  from  the  tjne  vocal  cords  and  seems  to  occur  by 
diapedesis,  since  it  is  readily  controlled  by  a  small  in- 
jection of  nitrate  of  silver. — St.  Petersburger  Medicinische 
Wochenschrijt^  April  26,  1884. 

An  Artificial  Sponge. — Dr.  Sampson  Gamgee  de- 
scribes in  The  Lancet  of  May  3,  1884,  a  sponge  devised 
by  him,  which  combines  absorbing  power  with  elasticity, 
and  is  cheap  enough  to  be  burnt  after  use,  thus  render- 
ing sponge  infection  impossible.  It  consists  of  an  inner 
bidl  of  absorbent  cotton,  surrounded  with  a  wad  of  cocoa^ 
nut  fibres,  around  which  again  is'  a  layer  of  absorbent 
cotton,  the  whole  being  enclosed  in  a  gauze  envelope. 
He  found  that  a  ball  so  made  takes  up  readily  from  six- 
teen to  eighteen  times  its  own  weight  of  blood  or  water, 
which  when  squeezed  out  still  leaves  the  ball  elastic  and 
absorbent.  The  sponge  may  be  rendered  antiseptic  by 
means  of  a  very  brittle  ball  or  capsule,  containing  any 
antiseptic  desired,  and  enclosed  within  the  inner  nucleus 
of  cotton.  By  giving  the  sponge  a  preliminary  sijueeze, 
the  capsule  is  broken  and  the  antiseptic  fluid  set  free. 

A  New  Remedy  for  Phthisis. — Aluminium  and  its 
compounds  are  affirmed  by  Dr.  Pick  to  constitute  a  most 
effective  remedy  against  pulmonary  tuberculosis,  this 
opinion  being  based  on  experiments  upon  rabbits  as  well 
as  on  clinical  observations.  In  one  case,  where  infiltra- 
tion of  the  apices  of  the  lungs  had  occurred,  removal  of 
the  lesion  and  all  the  morbid  symptoms  is  said  to  have 
followed  the  administration  of  aluminium  in  the  following 
form :  Metallic  aluminium,  eight  grammes ;  aluminium 
hydrate,  five  grammes ;  calcium  carbonate,  five  grammes ; 
gum  tragacanth,  in  sufficient  quantity  ;  divided  into  sixty 
pills,  one  pill  being  taken  three  times  a  day. — The  Lan^ 
cet^  May  3,  1884. 

Diabetic  Coma. — A  case  is  related  in  The  Lancet  of 
d  young  woman  who,  except  from  an  occasional  head- 
ache, seemed  to  be  in  good  health.  She  was  found  sit- 
ting in  a  chair,  apparently  in  a  profound  sleep,  from 
which,  however,  she  could  not  be  roused,  except  that 
she  would  raise  her  hand  to  her  head  when  spoken  to 
loudly.  All  attempts  at  resuscitation  were  in  vain,  the 
coma  gradually  deepened,  and  the  girl  died.  There  was 
no  vomiting.  At  the  autopsy  no  organic  disease  of  any 
of  the  organs  could  be  discovered,  but  the  tissues  gave 
forth  a  strong  diabetic  odor,  and  examination  of  the  urine 
showed  the  presence  of  sugar  in  considerable  quantity. 
_^ . 

}  The  period  of  latency  in  the  case  of  Captain  W api>ean  to  have  been  about 

five  days,  though,  as  he  was  ashore  two  or  three  times  prior  to  the  4th,  it  i»  un- 
certain.    With  Q and  F it  was  eleven  or  twelve,  and  tfauteen  diay% 

respectively. 


lO 


THE   MEDICAL  RECORD. 


[July  5,  1884 


Carbolic  Acid  in  Muscular  Rheumatism. — Dr. 
Hurz  recommends  the  employment  of  carbolic  acid  in 
intra-muscular  injections  for  the  relief  ot  pain  in  muscu- 
lar rheumatism.  He  uses  a  solution  of  i-ioo  or  1-50. 
The  injections  are  not  painful,  causing  at  the  most  but 
a  slight  burning  sensation.  The  analgesic  effect  is  mani- 
fested within  fifteen  or  tWenty  minutes. — L  Union  Medi- 
cale  du  Cancula^  May,  1884. 

Mammary  AxROPftv. — Dr.  J.  W.  Reynolds  writes  to 
The  Lancet  concerning  a  patient  of  his  who  is  now  in  her 
fiftieth  year.  She  ceased  to  menstruate  about  three  or 
four  years  ago,  and  has  borne  six  children.  After  wean- 
ing her  first  child,  which  she  nursed  for  a  few  weeks  only, 
she  being  twenty-one,  her  mammae  completely  disap- 
peared ;  not  a  vestige  of  gland  could  be  felt,  and  there 
was  no  loose  skin,  but  the  chest  and  abdomen  were  as 
smooth  as  those  of  a  child  ;  but  when  she  became  preg- 
nant the  mammary  glands  enlarged  to  a  very  fair  size, 
and  there  was  an  abundant  supply  of  milk — too  profiise, 
in  fact,  for  it  ran  away  continuously ;  and  as  it  weakened 
her  and  did  not  nourish  the  child,  she  had  to  discontinue 
nursing.  Then  the  glands  would  gradually  disappear, 
the  skin  contract,  and  everything  become  smooth  again. 
So  with  every  pregnancy.  Now,  at  fifty,  her  chest  and 
abdomen  are  as  smooth  as  any  young  girl's — ^no  loose 
folds  of  skin  or  rugae. 

Cider  as  a  Prophylactic  of  Stone  in  the  Bladder. 
— Dr.  Denis  Dumont  has  examined  the  statistics  of  the 
Caen  Hospital,  and  found  that  in  fifty-nine  years  only 
four  cases  of  stone  in  the  bladder  were  admitted.  In 
one  the  nucleus  was  a  foreign  body ;  and  in  two  the  pa- 
tients drank  wine,  and  not  cider,  which  is  the  ordinary 
beverage  in  Normandy.  An  inquiry  made  in  the  neigh- 
boring departments  of  the  Manche  and  Ome,  showed 
that  stone  in  the  bladder  was  extremely  rare  where  the 
use  of  cider  was  the  rule.  Meat  being  cheap  and 
abundant  in  Normandy,  the  rarity  of  stone  cannot  be 
ascribed  to  the  use  of  a  food  containing  less  nitrogenous 
substances  than  in  other  countries.  The  remarkable 
diuretic  properties  of  cider,  which  the  author  has  found 
usefiil  in  gravel,  obesity,  and  some  forms  of  gastritis,  are 
considered  to  afford  an  explanation  of  this  remarkable 
freedom  from  calculus. — Birmingham  Medical  Review^ 
May,  1884. 

The  Prevention  of  Blindness  in  Infancy. — ^The 
following  instructions,  based  upon  the  directions  of  the 
Society  for  the  Prevention  of  Blindness,  have  been  issued 
by  the  Manchester  and  Salford  Sanitary  Association,  for 
the  information  of  mothers  and  nurses  {Practitioner^ 
May,  1884) :  "  One  of  the  most  frequent  causes  of 
blindness  is  the  inflammation  of  the  eyes  of  new-bom 
babies.  Yet  this  is  a  disease  which  can  be  entirely  pre* 
vented  by  cleanliness,  and  always  cured  if  taken  in  time. 
The  essential  precautions  against  the  disease  are : 
I.  Immediately  after  the  birth  of  the  baby,  and  before 
anything  else  is  done,  wipe  the  eyelids  and  all  parts  sur- 
rounding the  eyes  with  a  soft  dry  linen  rag  ;  soon  after- 
ward wash  these  parts  with  tepid  water  before  any  other 
part  is  touched.  2.  Avoid  exposing  the  baby  to  cold 
air ;  do  not  take  it  into  the  open  au*  in  cold  weather ; 
dress  the  infant  warmly,  and  cover  its  head,  because  cold 
is  also  one  of  the  causes  of  this  eye  disease.  When  the 
disease  appears  it  is  easily  and  at  once  recognized  by  the 
redness,  swelling,  and  heat  of  the  eyelids,  and  by  the 
discharge  of  yellowish  white  matter  from  the  eye.  /m- 
mediately  on  the  appearance  of  these  signs  seek  the  advice 
of  a  medical  man;  but  in  the  meantime  proceed  at  once 
to  keep  the  eyes  as  clean  as  possible  by  very  frequently 
cleansing  away  the  discharge.  It  is  the  discharge  which 
does  the  mischief.  The  cleansing  of  the  eye  is  best  done 
in  this  way  :  i.  Separate  the  eyelids  with  the  finger  and 
thumb,  and  wash  out  the  matter  by  allowing  a  gentle 
stream  of  lukewarm  water  to  run  between  them  from  a 
piece  of  rag  or  cotton-wool  held  two  or  three  inches 
above  the  eyes.    2.  Then  move  the  eyelids  up  and  down 


and  from  side  to  side  in  a  gentle,  rubbing  way,  to  bring 
out  the  matter  from  below  them  ;  then  wipe  it  or  wash  it 
off  in  the  saaie  manner.  This  cleansing  will  take  three 
or  four  minutes,  and  it  is  to  be  repeated  regularly  every 
half  hour  at  first,  and  later,  if  there  is  less  discharge^ 
every  hour.  3.  The  saving  of  the  sight  depends  entirely 
on  the  greatest  care  and  attention  to  cleanliness.  Small 
pieces  of  clean  rag  are  better  than  a  sponge,  as  each  rag 
is  to  be  used  once  only  and  then  burnt  immediately ; 
sponges  should  never  be  used,  except  they  are  burnt 
after  each  washing.  4.  A  little  washed  lard  should  be 
smeared  along  the  edges  of  ^the  eyelids  occasionally  to 
prevent  them  from  sticking.  Special  warning:  Of  all 
the  mistaken  practices  which  ignorance  is  apt  to  resort 
to,  none  is  more  ruinous  than  the  use  of  poultices.  Let 
them  be  dreaded  and  shunned  as  the  destroyers  of  a  new- 
born baby's  sight.  Tea-leaves  and  sugar  of  lead  lotion 
are  equally  conducive  to  terrible  mischief,  stopping  the 
way  as  they  do  to  the  only  right  and  proper  course  to  be 
taken." 

Brittle  Bones. — A  case  was  recently  reported  to  the 
Suffolk  Medical  Society,  by  Dr.  Douglas  Graham,  of  a 
patient  who  had  sustained  eighteen  fractures  during  the 
first  eighteen  years  of  his  life.  They  were  distributed  as 
follows :  The  right  arm,  broken  nine  times ;  left  arm, 
twice  ;  left  leg,  three  times ;  right  leg,  twice  ;  right  and 
left  clavicle,  once  each.  The  patient's  father  J^roke  his 
bones  fourteen  times,  and  the  father's  cousin  twenty-one 
times.  The  father's  uncle  was  also  a  bone-breaker. — 
Boston  Medical  and  Surgical  Journal^  May  15,  1884. 

Increase  in  the  Length  of  the  Leg  following 
Rheumatism. — Dr.  Vinals  reported  to  the  Medico-Chi- 
rurgical  Academy  of  Spain,  the  case  of  a  young  man  in 
whom  an  increase  of  two  inches  in  the  length  of  the  leg 
was  observed  to  follow  upon  an  attack  of  rheumatism  in 
the  knee.  The  reporter  thoujght  it  due  to  increased  ac- 
tivity excited  in  the  still  growing  epiphyses  by  the  articu- 
lar inflammation,  ^he  inequality  was  not  permanent,  as 
the  affected  limb  was  in  time  overtaken  in  growth  by  its 
fellow. — Revista  de  Medicina  y  Cirugia  Prdcticas^  April 
22,  1884. 

SpiRiCA  Ulmaria  in  Enlarged  Prostate. —  Accord 
ing  to  Bauch,  the  queen  of  the  meadows  {spiraa  ulmaria) 
is  destined  to  occupy  an  important  place  in  the  thera- 
peutics of  diseases  of  ,the  genito-urinary  apparatus.  He 
has  administered  an  infusion  of  this  plant  to  patients 
with  enlarged  prostate  in  whom  urination  or  the  passing 
of  a  catheter  was  very  difficult,  and  within  half  an  hour 
they  urinated  abundantly  and  freely.  The  queen  of  the 
meadows  is  diuretic,  astringent,  and  antispasmodic,  and 
exerts  a  special  action  on  the  sphincter  of  the  bladder, 
spasm  in  which  it  relaxes. — Revista  de  Medicina  y  Ciru- 
gia Prdcticas^  April  22,  1884. 

Treatment  of  Scrofulous  Adenopathies. — Dr. 
Garcia  Andradas  claims  to  have  obtained  excellent  results 
in  the  treatment  of  sloughing  scrofulous  glands  with  the 
solution  of  the  perchloride  of  iron  {El  Dictamen^  April 
30,  1884).  He  paints  the  surface  of  the  caseous  mass 
with  the  solution,  and  states  that  the  slough  is  soon  cast 
off,  leaving  a  healthy  granulating  surface.  This  readily 
heals  under  an  ointment  of  turpentine  and  vaseline,  one 
part  to  fifteen.  Of  course  the  constitutional  treatment 
is  not  to  be  neglected. 

Physiological  Albuminuria. — At  a  recent  meeting  of 
the  Soci^t^  de  M6decine  of  Paris,  M.  Coignard  reviewed 
and  criticised  the  theories  concerning  albuminuria,  and 
also  the  thesis  on  this  subject  written  under  the  direction 
of  Professor  Bouchard.  According  to  his  personal  ob- 
servations, and  those  of  a  number  of  cases  collected  by 
Keller,  physiological  albuminuria  does  not  exist  M* 
Coignard  admitted  the  existence  of  transitory  albumi- 
nuria, as  also  of  transitory  glycosuria,  but  denied  that 
albumen  is  ever  found  in  the  urine  of  perfecdy  healthy 
individuals. — British  Medical  Journal^  May  24,  1884. 


July  5,  1884.] 


THE  MEDICAL   RECORD. 


II 


The  Cause  of  Cholera. — Mr.  Vincent  Richards  has 
been  conducting  some  experiments  on  pigs  in  regard  to 
the  cause  of  cholera,  which  have  led  him  to  very  different 
conclusions  from  those  of  Koch  {Indian  Medical  Ga- 
leife).  He  states  that  the  choleraic  discharges  contain  a 
virulent  poison,  which,  however,  disappears  within  a  few 
hoursy  when  decomposition  has  begun.  He  supposes 
the  poison  to  be  a  chemical  compound,  and  not  a  micro- 
organism, since  he  has  found  that  it  is  destroyed  by 
potassium  permanganate.  If  the  evacuations  are  rapidly 
desiccated  without  decomposition,  the  poison  may  retain 
its  virulence  for  a  considerable  length  of  time  and  in  this 
way  b^  transported  by  fomites.  He  believes  that  the 
poison  acts  by  paralyzing  respiration. 

The  Significance  of  the  Patellar  Tendon  Reflex 
IN  General  Paresis  of  the  Insane. — The  following 
are  the  conclusions  of  a  paper  on  this  subject  by  Pro- 
fessor L.  Bianchi  in  11  Mavimento  of  May  15,  1884  :  i. 
Exaggeration  of  the  patellar  tendon  reflex  may  be   a 
valuable  diagnostic  sign  in  the  beginning  of  the  disease, 
especially  in  those  cases  in  which  the  dUire  de  grandesse 
is  not  accompanied  by  disturbances  of  speech.     2.  Al- 
though at  the  commencement  of  the  disease  it  is  as  a  rule 
exaggerated,  it  may  in  the  further  progress  of  the  malady 
undergo  certain  changes.     More  often  it  diminishes  or 
disappears,  rarely  becomes  more  exaggerated  than  be- 
fore.    3.  By  itself,  whether  exaggerated  or  abolished,  it 
does  not  indicate  a  determinate  anatomical  lesion  of  any 
special  region  of  the  cord  occurring  as  a  complication  of 
general  paresis.     Therefore,  instead  of  being  considered 
as  the  expression  of  certain  recent  morbid  processes,  it 
should  be  studied  in  connection  with  the  other  symptoms 
of  the  disease,  and  not  by  itself  or  at  any  special  period 
in  the  course  of  the  malady. 

Morphinism  and  Pregnancy. — Dr.  Fer6  relates  the 
case  of  a  young  womaq  addicted  to  the  use  of  morphine 
in  rather  moderate  quantity  (about  3^  grains  a  day),  who, 
when  in  the  sixth  month  of  pregnancy,  endeavored  to 
break  off  the  habit.     But  any  sudden  diminution  in  the 
daily  amount  taken  caused  such  severe  uterine  colic  that 
the    progress  toward  recovery  was   very  slow.     At  the 
time  of  delivery  she  was  taking  about  two  grains  per 
diem,  and  no  attempt  to  reduce  this  quantity  was  made 
for  a  week.     It  was  then  sought  to  lengthen  the  intervals 
between   the   hypodermic  injections,   but   the    uterine 
pains  returned  and  the  lochia!  discharge  ceased  and  did 
not  reappear  until  the  injections  were  resumed.     At  the 
end  of  a  month  the  daily  quantity  of  morphine  had  been 
reduced  to  a  little  more  than  one  grain,  and  it  was  then 
widiheld  entirely.     The  patient  suffered  severely  from 
uterine  and  intestinal  colic  and  was  unable  to  sleep  the 
first  night,  but  the  following  day  all  these  unpleasant 
symptoms  ceased,  and  she  was  definitely  cured.     The 
dSect  of  the  sudden  abstinence  upon  the  child,  when 
bixth  removed  him  from  the  influence  of  the  drug,  was 
evident.     He  was  a  well-developed  boy,  though  emaci- 
ated.    He  suffered  from  convulsive  twitchings  with  con- 
tinuous agitation  and  crying  for  sixty  hours,  during  which 
time  he  did  not  sleep  a  minute.     After  that  he  recovered, 
slept  well,  and  acted  naturally.     This  fact  would  seem 
to  indicate  that,  whatever  may  be  said  to  the  contrary, 
the  foetus  is  influenced  by  morphine  even  in  relatively 
small  doses,  and  that  it  may  suffer  from  the   sudden 
abstinence  enforced  by  birth.     This  last  consideration 
indicates  the  necessity  of  a  gradual  withdrawal  of  the 
drug  in  the  case  of  opium-eaters  who  become  pregnant. 
— 11  Mamtnento^  May  15,  1884. 

Diagnosis  of  Pleuritic  Exudations  by  the  Tun- 
ing-fork.— The  following  are  Dr.  Federico's  conclusions 
relative  to  the  utility  of  the  tuning-fork  in  the  diagnosis 
of  pleuritic  effusions  and  exudations  {Gazzeita  Medica  di 
Romdy  May  i,  1884)  :  i.  If  the  vibrating  tuning-fork  be 
applied  to  any  part  of  a  normal  thorax,  a  full,  distinct, 
and  augmented  sound  results.  2.  When  made  to  vibrate 
while  in  contact  with  thoracic  parietes  within  which  there 


exists  an  effusion,  and  particularly  if  placed  over  that 
portion  of  the  chest  where  the  dulness  on  percussion  is 
most  marked,  the  tuning-fork  emits  a  short,  obscure,  and 
muffled  tone.  3.  The  sound  is  shorter  and  more  muffled 
in  proportion  as  the  fluid  is  more  abundant.  4.  Although 
the  author  has,  thus  far,  only  experimented  with  serous 
effusions,  he  inclines  to  the  belief  that  the  sonorous 
vibrations  of  the  instrument  would  be  still  more  weak- 
ened and  obscured  if  the  effusion  werp  rich  in  corpuscular 
elements.  This  theory  derives  support  from  the  fact, 
experimentally  demonstrated  by  the  author,  that  the 
vibrations  of  a  tuning-fork  immersed  in  a  watery  fluid 
contained  in  a  thin  vessel  are  communicated  to  the 
receptacle,  while  the  vibrations  cease  to  be  perceptible 
when  the  serous  fluid  is  replaced  by  a  purulent  one.  The 
author  recommends  the  adoption  of  the  following  pre- 
cautions in  the  application  of  the  tuning-fork  to  its  pro- 
posed diagnostic  use:  i.  The  instrument  should  be 
placed  in  contact  with  corresponding  parts  of  both  the  nor- 
mal and  diseased  half  of  the  thorax,  for  purposes  of  com- 
parison. 2.  An  instrument  with  long  branches  facilitates 
the  perception  of  slight  variations  in  pitch  and  quality. 

3.  The  vibrations  imparted  to  the  tuning-fork  should  be 
of  moderate  intensity  lest  they  be  transmitted  to  the 
stomach  and  colon  and  be  thereby  unduly  augmented. 

4.  A  certain  amount  of  force  should  be  employed  in 
holding  the  instrument  in  contact  with  the  chest-wall,  as 
the  vibrations  are  not  well  transmitted  if  this  precaution 
be  omitted. 

Origin  of  Musical  Diastolic  Aortic  Murmurs. — 
Dr.  Groedel,  of  Nanheim,  reaches  the  following  conclu- 
sions regarding  diastolic  aortic  murmurs  (^Berliner  Klin- 
ische  Wochenschrift^  April  21,  1884)  :  The  murmurs  in 
question,  often  perceptible  at  considerable  distance  from 
tlie  seat  of  their  production,  are  caused  by  insufficiency 
of  the  aortic  semilunar  valves,  if  the  valves  are  in  such  a 
condition  that  tliey  may  be  put  in  regular  and  equal 
vibration,  during  the  entire  diastole,  by  the  regurgitant 
blood  current.  The  above  condition  obtains,  first,  when 
the  first  portion  of  the  aortic  arch  is  dilated  and  relative 
insufficiency  of  the  valves  is  thus  produced ;  and,  second- 
ly, in  cases  of  genuine  insufficiency,  provided  the  valves 
be  still  capable  of  vibrating  regularly  and  evenly. 

A  Substitute  for  the  Cold  Bath  in  Fevers. — 
Professor  Preyer,  of  Jena,  publishes  in  the  Berliner 
Klinische  Wochenschrift^  May  5,  1884,  an  extract  from 
a  paper  read  by  himself,  at  a  meeting  of  the  Jena  Medical 
and  Natural  History  Society,  on  a  novel  method  of  re- 
ducing animal  temperature.  The  experiments  upon 
which  Professor  Preyer*  s  suggestions  relative  to  the  pro- 
duction of  antipyresis  are  based  were  performed  upon 
Guinea-pigs,  but  seem  to  show  that  the  new  method 
may  be  equally  applicable  to  man.  The  means  of  re- 
frigeration employed  was  the  water  spray.  When  the 
temperature  of  the  water  used  was  between  40°  and  45° 
F.,  the  rectal  temperature  of  the  animals,  was  reduced 
about  2°  within  from  five  to  ten  minutes.  If,  after  the 
discontinuance  of  the  spray,  the  minute  particles  of 
water  entangled  in  the  hair  be  allowed  to  slowly  evapo- 
rate, the  temperature  continues  gradually  to  diminish 
for  several  hours.  If  water  at  the  temperature  of  70**  F. 
be  employed  the  refrigeration  is  manifested  within  twenty 
minutes,  but  is  not  so  pronounced.  The  rapidity  and 
the  degree  of  the  antipyretic  effect  may  thus  be  easily 
regulated  by  modifications  in  the  temperature  of  the 
water  used,  and  of  the  interval  during  which  the  spray 
is  applied.  The  author  states  that  the  object  of  this 
communication  is  to  incite  to  farther  experimentation  on 
animals  as  well  as  on  the  human  subject. 

Antiseptic  Properties  of  Bichromate  of  Potas- 
sium.—Some  experiments  recently  conducted  in  France 
show  that  urine,  blood,  milk,  and  other  substances  can 
be  preserved  from  putrefaction  during  several  months  by 
the  addition  of  one  per  cent  of  their  weight  of  this  salt. 
— Cincinnati  Lancet  and  Clinic^  May  10,  1884. 


12 


THE  MEDICAL  RECORD. 


[July  5,  1884. 


Phlebitis  Complicating  Rheumatism. — M.  Schmitt 
establishes  two  varieties  of  phlebitis  accompanying  acute 
articular  rheumatism.  One  form  of  the  disease  manifests 
itself  at  the  height  of  the  rheumatic  attack  and  augments 
the  local  pains  and  the  temperature,  while  the  joints 
become  less  tense  and  swollen.  The  phlebitis  usually 
develops  at  the  point  of  junction  of  the  deep  and  super- 
ficial veins.  Sometimes  the  veins  remain  permeable, 
the  symptoms  being  confined  to  slight  oedema,  slight 
redness  along  the  course  of  the  vessels,  and  moderate 
pain.  More  frequently,  however,  this  form  of  phlebitis 
produces  obliteration  of  the  veins,  with  more  pronounced 
oedema,  a  cord- like  induration,  and,  possibly,  with  pete- 
chias, ulcerations,  and  even  pulmonary  embolism.  The 
second  variety  of  phlebitis  appears  at  the  termination  of 
the  rheumatic  attack,  rapidly  producing  occlusion  of  the 
vessel,  with  more  oedema,  and  with  pain  of  considerable 
intensity.  The  phlebitis  persists  for  several  weeks,  oc- 
casioning difficulty  in  walking  and  in  moving  the  limbs. 
The  femoral,  popliteal,  and  saphenous  veins  are  most 
frequently  affected,  but  the  radical  and  brachial  are 
sometimes  involved. — Archives  Midicales  Beiges,  April, 
1884. 

Concealment  of  the  Cicatrix  after  Removal  of 
Mammary  Tumors. — M.  D.  MoUi^re  describes  an  opera- 
tion, devised  by  himself,  for  the  purpose  of  hiding  the 
cicatrix  resulting  from  the  ablation  of  an  adenoma  of  the 
breast,  located  in  the  lower  part  of  the  gland.  The 
tumor  was  about  the  size  of  an  egg,  and  became  regularly 
tumefied  during  the  week  preceding  menstruation,  re- 
suming its  former  dimensions  after  the  cessation  of  the 
monthly  flow.  The  operation  was  performed  as  follows  : 
A  transverse  incision  having  been  made  in  the  course  of 
the  submammary  fold,  the  cellular  tissue  behind  the 
mamma  was  separated  from  the  glandular  tissue,  the 
encapsulated  adenoma  easily  enucleated,  and  a  drainage 
tube  inserted.  Union  occurred  by  first  intention,  and 
the  small  linear  cicatrix,  being  situated  at  the  bottom 
of  the  submammary  cutaneous  fold,  was  completely  hid- 
den by  the  gland  in  its  natural  dependent  position. — 
Archives  Medicates  Beiges^  April,  1884. 

Nervous  Diarrhceas. — Professor  H.  Nothnagel  for- 
mulates the  following  conclusions  regarding  diarrhoeas  of 
purely  neuropathic  origin  :  Nervous  diarrhoeas,  first  so 
designated  by  Trousseau,  are  those  which  occur  as  the 
result  of  anxiety,  fright,  or  various  other  intense  physical 
impressions,  and  occasionally  in  hysteria,  but  which  are 
unattended  by  intestinal  inflammation.  The  diarrhoeas 
in  question  may  be  chronic  as  well  as  acute.  In  certain 
individuals  the  above-mentioned  etiological  agencies 
merely  occasion  abnormal  frequency  of  the  alvine  dejec- 
tions. In  other  cases  depressing  mental  impressions  may 
cause  a  purely  nervous  diarrhoea  to  be  engrafted  upon  a 
chronic  enteritis,  and  to  notably  prolong  the  duration  of 
the  latter.  The  author  cites  cases  illustrative  of  this  dis- 
ease, which,  in  his  opinion,  justify  the  establishment  of 
two  varieties  of  nervous  diarrhoeas.  In  one  category  be- 
long cases  in  which  the  evacuations  are  of  fluid  consist- 
ency, in  the  other  those  attended  by  formed  or  hardened 
dejections.  In  the  latter  form  the  author  believes  that 
the  nervous  influence  resulting  in  increased  frequency  of 
defecation  is  exerted  upon  the  lowest  portion  of  the  large 
intestine  in  which  fecal  matter  is  already  accumulated. 
In  this  case  the  only  abnormal  feature  of  the  process  is 
the  occurrence  of  evacuations  at  unusually  frequent  in- 
tervals. A  different  nervous  mechanism  must  be  invoked 
to  explain  the  occurrence  of  the  fluid  evacuations.  The 
author  assumes,  in  these  cases,  that  either  the  entire 
bowel  is  affected  by  violent  peristaltic  movements,  which 
mingle  the  fluid  constituents  of  the  discharges  emanating 
from  the  small  intestine  with  the  solid  fecal  matter  of  the 
colon,  or  that  an  abundant  transudation  of  serum,  occur- 
ring in  the  large  intestine  itself,  liquefles  the  solid  matter 
previously  accumulated  therein.  Professor  Nothnagel 
inclines  m  favor  of  the  latter  theory,  although  unable  to 


furnish  convincing  proofs  of  its  accuracy.  The  exciting 
influences  resulting  in  these  two  forms  of  diarrhoea  must 
produce  their  effect  through  different  nervous  channels. 
In  one  case  those  nerves  which,  under  stimulation,  oc- 
casion increased  peristalsis  are  incited  to  functional 
activity,  in  the  other  the  vaso-motor  and  secretory  nerves 
are  chiefly  instrumental  in  producing  the  diarrhoea. — 
Allgemeine  Medicinische  Central-Zeiiung,  yi^y  14,  1884. 
The  Differential  Diagnosis  of  Syphilitic  Neu- 
ralgia.— Dr.  Diffre  {Gazzetta  Medica  di  Roma,  May  i, 
1884)  expresses  the  belief  that  the  symptomatology  of 
syphilitic  neuralgia  furnishes  the  most  useful  data  for  its 
differentiation  from  other  forms  of  the  disease.  The  clin- 
ical history  and  the  results  of  treatment  may  also  furnish 
considerable  assistance.  The  author  asserts  that  the  pain 
of  syphilitic  neuralgia  is  intermittent,  and  that  it  manifests 
spontaneous  exacerbations.  If  excited  by  mechanical 
means  its  intensity  is  diminished.  The  intensity  of  the 
spontaneous  variety  may  var^  from  the  lowest  grades  to 
such  degrees  of  pain  as  might  be  produced  by  strong 
electric  currents  or  the  actual  cautery.  The  pain  ex- 
tends along  the  course  of  the  nerves,  and  is  frequently 
limited  to  small  areas.  The  neuralgic  attacks  are  less 
frequent  during  the  day,  and  even  when  observed  at  that 
time  areof  much  less  intensity  than  when  occurring  at  night. 

Reflex  Paralysis. — A  woman,  thirty-four  years  of 
age,  multipara,  was  admitted  to  hospital  in  the  service 
of  Dr.  Gomez  Torres,  suffering  from  paralysis  and  atro- 
phy  of  the  upper  extremities.  Some  months  previous  to 
her  admission  she  had  noticed  that  her  hands  were  becom- 
ing thin  and  that  she  was  gradually  losing  all  power  in 
them.  The  paralysis  and  atrophy  increased  in  spite  of 
persistent  electrical  and  other  treatment,  until  at  this 
time  she  was  unable  to  extend  the  hands  at  all,  and  the 
thenar  eminences  had  entirely  disappeared.  Examina- 
tion showed  that  she  was  suffering  also  from  chronic 
parenchymatous  metritis  and  extelisive  ulceration  of  the 
cervix.  The  diagnosis  of  reflex  paralysis  was  made  and 
was  conflrmed  by  the  results  of  treatment,  for  the  paraly- 
sis and  atrophy  rapidly  disappeared  as  the  local  affection 
was  relieved  by  appropriate  measures. — El  Dictamen, 
May  20,  1884. 

Some  Peculiar  Forms  of  Aphasia. — Dr.  Brown- 
S6quard,  at  a  recent  meeting  of  the  Soci6t6  de  Biologie 
of  Paris  (Gazette  des  Hopitaux,  No.  48,  1884),  re- 
counted some  curious  facts  concerning  aphasia.  The 
first  case  was  that  of  an  individual  who  had  lost  entirely 
the  faculty  of  speech.  He  possessed  but  one  word  in 
his  vocabulary  with  which  he  sought  to  express  all  his 
ideas.  Yet  he  was  able  to  sing  in  a  loud  voice,  enuncia- 
ting the  words  and  rendering  the  music  with  artistic  feel- 
ing. The  second  case  was  that  of  a  physician  of  Cincin- 
nati, who  had  become  aphasic  in  consequence  of  softening 
of  the  brain.  This  patient  had  lost  completely  the  use 
of  language  during  his  waking  moments,  but  talked  well 
in  his  dreams.  The  third  instance  was  observed  in  an 
individual  who  was  likewise  suffering  from  complete 
aphasia  in  consequence  of  a  cerebral  lesion.  His  powers 
of  speech  were  restored  during  times  in  which  he  was 
delirious.  Dr.  Richet  related  a  fact  somewhat  resem- 
bling those  just  cited  concerning  an  old  woman  who  had 
been  the  servant  of  a  priest.  Just  before  she  died  she 
repeated  very  distinctly  a  number  of  Hebrew  words 
which  she  had  heard  her  master  pronounce  thirty-five 
years  before. 

NiTRFFE  OF  Amyl  IN  Ammoniacal  Urink. — ProfessoT 
Von  Dittel  observed  at  the  Vienna  Medical  Society  that 
he  had  for  a  long  time  past,  in  obstinate  cases  of  am- 
moniacal urine,  found  this  substance  very  usefuL  A 
solution  is  made  of  three  drops  in  one  hundred,  and  fifty 
of  water,  and  a  tablespoonful  of  this  is  added  to  about  a 
quart  of  water,  with  which  the  bladder  is  washed  out 
The  unpleasant  smell  of  the  urine  diminishes  immediately, 
and  is  replaced  by  a  pleasant  ether  odor. — Dublin 
Journal  of  Medical  Science^^Mn^y  1884. 


July  5,  1884.] 


THE   MEDICAL  RECORD. 


13 


Thk  Bubbling  Carbonic  Water  Baths  of  Nauheim. 
— Drs.  Augustus  and  Theodore  Schott  publish  an  article 
under  the  above  title  in  the  Berliner  Klinische  Wochen- 
sckrift^  No.  19,  1884.  The  object  of  the  paper  is  to 
give  an  unbiased  statement  regarding  the  chemical  com- 
position of  the  Nauheim  carbonic  acid  waters,  together 
with  their  nature,  their  modus  operandi^  and  the  indica- 
tions for  their  use.  Preceding  the  paper  proper  are  cer- 
tain general  remarks  on  the  history  of  carbonic  acid 
water  baths.  The  analysis  of  the  waters,  conducted  un- 
der the  supervision  of  Prof.  Fresenius,  shows  that  they 
contain  an  amount  of  carbonic  acid  gas  fully  equal  to  that 
of  any  other  springs.  The  chief  indication  for  the  car- 
bonic acid  baths  is  found  in  the  emaciation  and  anaemia 
attendant  upon  chronic  diseases,  and  in  moderate  degrees 
of  cardiac  insufficiency  resulting  from  constitutional  dis- 
eases. High  grades  of  anaemia  and  of  cardiac  weakness, 
however,  contra-indicate  the  use  of  these  baths,  and  are 
aggravated  by  them. 

Iodide  of  Potassium  in  Pneumonia. — Regarding 
pneumonia  as  a  general  disease  with  local  manifestations, 
Dr.  Schwarz  recommended  the  use  of  iodide  of  potassium 
in  sii-grain  doses  every  two  hours,  at  the  same  time  apply- 
ing an  ice-bag  to  the  chest  over  the  seat  of  the  pulmo« 
nary  lesion.  All  his  cases  thus  treated  recovered,  some 
of  them  within  two  days.  Dr.  Gualdi  {Gazzeiia  Medica 
iiRoma^  May  15,  1884)  has  similarly  treated  a  number 
of  cases,  and  reports  most  excellent  results.  He  formu- 
lates the  following  conclusions  based  upon  his  experience 
with  this  mode  of  treatment:  i.  Schwarz' s  method  of 
treating  pneumonia  gives  good  results.  2.  These  results 
are  even  better  in  the  case  of  children  than  in  that  of 
addts.  3.  The  treatment  should  be  instituted  at  the 
beginnmg  of  the  disease,  for  when  commenced  at  a  later 
stage  the  cure  is  less  rapid  and  satisfactory.  4.  The  ac- 
tion of  the  iodide  is  exerted  upon  the  fever  and  the  gen- 
eral disease,  and  not  upon  the  local  lesion.  5.  The 
iodine  and  the  potassium  become  separated  within  the 
organism  and  each  of  them  exerts  a  special  effect.  6. 
The  action  of  the  ice  is  upon  the  local  condition.  It  is 
Qsdiil  in  the  period  of  pulmonary  congestion,  but  in- 
jnrious  in  the  stage  of  hepatization. 

NiTRFTE  OF  Amyl  IN  Opium-poisoning. — Dr.  W.  L, 
Johnson  reports  in  the  Texas  Courier-Record  for  May, 
1884,  a  case  of  opium-poisoning  treated  by  inhalations 
of  nitrite  of  amyl.  The  patient  when  first  seen,  three 
hoors  after  having  taken  two  ounces  of  laudanum,  was 
deeply  narcotized,  pulseless  at  the  wrist,  making  six  res- 
pizaddons  to  the  minute,  perspiring  freelv,  with  cold  ex- 
tremities, and  cyanotic.  Belladonna  and  other  remedies 
baving  failed,  twenty  to  thirty  drops  of  nitrite  of  amyl 
we  poured  upon  a  handkerchief  and  applied  to  the 
pwent's  nostrils.  After  two  inhalations  of  the  drug  the 
BttD  looked  up  and  asked  what  was  the  matter.  From 
tint  time  he  continued  to  improve  and  made  a  good 
ftcoTciy. 

Chill  as  an  Etiological  Factor  in  Pneumonia. — 
loan  address  delivered  before  the  Birmingham  Branch 
of  the  British  Medical  Association  {Birmingham  Medical 
Review,  June,  1884)  ^-  J-  Bumey  Yeo  expressed  the 
belief  that  chiU  has  a  causal  relation  of  some  sort  to 
many  cases  of  pneumonia,  but  thought  that  its  influence 
was  often  overrated.  It  is  notorious,  he  says,  that 
pneuinonia  often  occurs  during  the  prevalence  of  winds, 
especially  the  winds  of  spring ;  and  not  with  winds  from 
Mf  particular  quarter,  for  it  is  found  to  prevail  with 
nnthwest  winds  as  frequently  as  with  east  or  northeast 
winds.  Now,  in  this  connection  we  have  rather  over- 
looked the  fact  that  winds  are  carriers  of  dust  as  well  as 
conveyers  of  cold  (or  rather,  abstracters  of  heat) ;  and 
ftat  while,  on  the  one  hand,  they  carry  away  heat  from 
^  sarface  of  the  body,  on  the  other  hand  they  gather 
vp  di^t  of  all  kinds,  and  blow  all  manner  of  micro* 
oiganisins  bto  our  air-passages.  It  has  been  noticed 
H^n  and  again  that  all  depressing  agencies  may  predis- 


pose to  pneumonia,  such  as  exhaustion  from  physical 
fatigue  and  depressing  emotions,  and  it  may  be  that 
exposure  to  a  cold  wind  acts  both  as  a  predisposing 
cause,  by  the  depression  of  the  normal  resisting  power  it 
produces  by  rapid  abstraction  of  heat,  and  also  as  an  ex- 
citing cause,  by  means  of  the  micro-organisms  it  blows 
into  our  air-passages. 

A  Rare  Tumor  of  the  Orbit. — ^At  a  recent  meet- 
ing of  the  Academy  of  Medicine  in  Ireland  (Dublin 
Journal  of  Medical  Science^  June,  1884)  Mr.  Story  ex- 
hibited a  tumor  about  the  size  of  a  small  pea  which  he 
had  removed  from  the  orbit  of  a  girl  aged  twenty.  It 
had  existed  from  earliest  childhood,  and  had  lately  in- 
creased in  size.  The  tumor  lay  beneath  the  lower  lid 
toward  the  inner  canthus,  was  freely  movable  in  all 
directions,  strong  and  hard  to  the  touch,  and  was  covered 
by  slightly  discolored  skin.  When  the  patient  stooped, 
laughed,  cried,  or  took  violent  exercise,  this  patch  of 
bluish  skin  swelled.  When  the  superjacent  soft  parts 
were  divided  the  little  tumor  came  out  without  further 
interference.  On  section  it  was  found  solid,  and  formed 
of  a  series  of  irregularly  concentric  layers,  which  micro- 
scopical examination  showed  to  consist  of  fibrous  tissue 
and  calcified  matter  of  an  unknown  origin,  together  with 
cellular  conglomerations  of  an  indefinite  character. 
Nothing  resembling  either  bone  or  cartilage  existed  in 
the  tumor,  its  hardness  being  due  to  new  calcification. 
Mr.  Story  considered  the  tumor  to  be  a  phlebolith,  the 
history  of  the  case  and  the  pathological  appearances 
agreeing  with  that  view  as  to  its  nature. 

Treatment  op  Coryza. — Surgeon-Major  G.  E.  Dob- 
son  writes  in  The  Lancet  of  May  31,  1884,  describing  a 
plan  of  treatment  for  coryza,  which  is  certainly  simple 
enough,  and  which  he  claims  is  very  e£fective.  About  a 
drachm  of  camphor,  coarsely  powdered,  or  shredded  with 
a  knife,  is  placed  in  a  small  pitcher,  which  is  then  half 
filled  with  boiling  water.  The  patient,  having  made  a 
paper  cone  large  enough  to  surround  his  face  by  its  wide 
extremity  and  the  mouth  of  the  jug  by  its  narrow  end, 
proceeds  to  respire  freely,  at  each  inhalation  drawing  the 
steam  into  his  nostrils,  and  at  each  exhalation  forcing  it 
up  against  the  outer  surfaces  of  his  nose  and  adjoining 
parts  of  the  face.  A  twofold  action  is  produced :  the 
camphorated  steam  acts  internally  in  a  specific  manner 
upon  the  whole  extent  of  the  mucous  surfaces,  and  ex- 
ternally produces  profuse  diaphoresis  of  the  skin  cover- 
ing the  nose  and  face,  there  acting  as  a  derivative  from 
the  inflamed  Schneiderian  membrane.  The  pitcher 
should  be  wrapped  in  a  woollen  cloth  to  retain  the  heat 
in  the  water,  or,  better  still,  a  tin  vessel,  under  which  a 
spirit-lamp  is  burning,  may  be  used.  The  respirations 
should  be  continued  for  from  ten  to  twenty  minutes,  and 
should  be  repeated  three  or  four  times  in  as  many  hours. 
The  writer  asserts  that  great  relief  is  alwajrs  felt  even 
after  the  first  application,  and  that  three  or  four  usually 
effect  a  cure. 

A  New  Form  of  Cuirass  for  Pott's  Disease  in 
Young  Children. — As  a  substitute  for  the  plaster-of- 
Paris  jacket.  Professor  H.  C.  Wyman  {Medical  Age)  has 
devised  a  method  of  treatment  which  is  briefly  as  fol- 
lows :  The  child  being  placed  in  such  position  that  the 
spine  is  extended  to  nearly  the  normal  limit,  a  piece  of 
Canton  flannel,  large  enough  to  cover  one-third  of  the 
circumference  of  the  trunk,  is  laid  on  the  back.  A  sheet 
of  absorbent  cotton  having  been  placed  over  this,  a 
cheese-cloth  bandage  six  inches  wide  and  several  yards 
long,  with  the  meshes  carefully  filled  with  plaster-of-Paris, 
is  dipped  in  water  and  folded  lengthwise  over  the  whole. 
When  rubbed  sniooth  with  the  hand,  so  that  it  is  per- 
fectly adapted  to  the  contour  of  the  parts,  a  bandage  is 
applied  around  the  trunk,  with  figure-of-8  turns  about 
the  shoulders  and  pelvis,  and  the  plaster  allowed  to  set. 
The  jacket  thus  constructed  is  in  the  form  of  a  splint, 
and  can  be  removed  every  night. 


H 


THE  MEDICAL  RECORD. 


[July  5,  1884* 


The  Medical  Record 


A  Weekly  Journal  of  Medicine  and  Surgery, 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 

Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Lafayette  Place. 

New  York,  July  5,  1884. 

IMPROVEMENT  IN  INFANT  DIET. 

Any  step  toward  even  the  partial  solution  of  the  diffi- 
cult problem  of  artificial  feeding  during  infancy  will 
be  hailed  with  satisfaction  by  all  physicians.  The  heavy 
mortality  during  the  first  year  of  life  in  those  deprived 
of  breast  milk  is,  especially  in  cities,  an  important  factor 
in  the  compilation  of  death-lists.  Social  science  can 
roll  up  statistics,  but  is  unable  to  suggest  a  remedy.  In-> 
creasing  importance  is  given  to  this  question  when  we 
consider  the  large  number,  especially  of  American 
women,  who  cannot  or  will  not  nurse  their  children.  In 
the  majority  of  cases  a  wet-nurse  cannot  be  procured, 
either  from  their  scarcity  or  the  attendant  expense,  and 
an  artificial  diet  becomes  imperative.  A  host  of  infant 
foods  are  offered  as  a  perfect  substitute  for  the  mother's 
milk«  All  of  these  preparations,  however,  differ  widely 
from  the  milk  for  which  they  are  to  be  substituted.  As 
a  result,  while  some  infant  foods  may  produce  a  plump- 
ness, they  are  all  more  or  less  colicky  in  their  action. 
They  are  particularly  not  adapted  to  early  infancy,  when 
artificial  food  should  not  only  be  conformed  to  the  baby's 
digestion,  but  should  anticipate  any  future  disturbances 
that  are  so  apt  to  accompany  the  early  months  of  life. 
Some  of  the  preparations  contain  large  quantities  of  un- 
changed starch  that  a  young  baby  is  unable  to  digest. 
Even  the  Liebig  foods  only  claim  to  have  transformed 
starch  into  glucose  and  thus  removed  one  source  of 
trouble ;  but  the  greatest  cause  of  indigestion  in  cow's 
milk,  the  caseine,  is  not  directly  affected  by  them  at  all. 
It  is  true  they  are  valuable  by  physically  acting  as  at- 
tenuants  of  the  caseine,  as  the  arrowroot  and  cracker 
water  formerly  used,  but  they  exert  no  chemical  or 
physiological  action  upon  this  substance  that  is  the  source 
of  so  much  of  the  indigestion  during  infancy. 

In  188 1  a  council  was  held  at  Salzburg  for  the  purpose 
of  considering  the  subject  of  infant  diet.  Gerhardt, 
Henoch,  Biedert,  Soltmann,  and  other  leading  authori- 
ties were  present.  All  agreed  that  advances  in  physio- 
logy only  prove  that  mother's  milk  is  quantitatively  and 
qualitatively  best  suited  to  the  development  of  the 
child.  They  likewise  agreed  that  animal  milk  is  the 
best  substitute  for  breast  milk.  In  discussing  the  sub- 
ject of  infant  foods  the  chairman  stated  that  it  was 
unanimously  agreed  that  these  preparations  can  in  no 
way  be  substituted  for  mother's  milk,  and,  as  exclusive 
food  during  the  first  year,  are  to  be  entirely  rejected. 
The  important  question  then  to  be  considered  is,  how 


cow's  milk   can  be   best  modified  to  resemble  human 
milk. 

Before  discussing  this  question  we  will  briefly  notice 
the  well-known  points  of  difference  between  these  two 
varieties  of  milk.     Woman's  milk  is  thin  and  watery, 
with  a  peculiar  animal  taste  and  a  persistent  alkaline 
reaction.     Cow's  milk,  although  containing  more  water 
and  less  solid  ingredients,  is  more  opaque,  and  very  fre- 
quently has  a  shghtly  acid  reaction.     Human  milk  con- 
tains more  milk  sugar  and  fat,  but  a  smaller  percentage 
of  albuminoids  than  cow's  milk.     A  point  of  great  im- 
portance is  that  the  fraction  of  the  total  albuminoids 
coagulable  by  acids  in  cow's  milk  is  much  greater  than 
that  in  human  milk.     The  caseine  of  cow's  milk  does 
not  coagulate  in  soft  flakes  as  in  human  milk,  but  in 
harder  and  more  indigestible  masses.     The  usual  method 
of  preparing  cow's  milk  is  to  add  sufficient  water  to  re- 
duce the  percentage  of  caseine  to  its  relative  amount  in 
human  milk.     But  in  so  doing  the  sugar  of  milk  and  fat, 
both  already  in  smaller  quantities  in  cow's  milk  than  in 
woman's  milk,  have  their  amount  still  further  reduced* 
A  little  loaf  sugar  is  generally  added  to  bring  up  the 
saccharine  ingredients  to  their  normal  ratio.     Hence  to 
dilute  the   caseine  properly  the  fat  is  diluted  far  too 
much.     Now,  if  fat  is  removed  from  the  milk,  in  addition 
to  the  loss  of  nutrition  involved   in  its  absence,  the 
caseine  coagulates  in  still  harder  masses.     £ven  after 
the  proper  quantity  of  water  has  been  added  to  cow's 
milk,  with  perhaps  an  attenuant,  as  a  little  starch  or  gum, 
the  clot  is  only  partially  and  incompletely  diminished  in 
size  and  density.    The  problem,  then,  is  how  to  reduce 
the  caseine  and  increase  its  digestibility,  while  at  the 
same  time  the  other  important  ingredients  of  the  milk 
are  maintained  up  to  the  standard  of  human  milk. 

Professor  Pfeififer,  of  Wiesbaden,  in  considering  this 
subject  brought  out  the  valuable  idea  of  peptonizing  the 
milk.   By  this  process  the  hard  and  objectionable  caseine 
is  physiologically  changed  into  readily  soluble  peptone. 
The  principal  source  of  irritation  in  artificial  feeding  is 
thus  removed.     Cow's  milk  thus  treated  becomes  thinner 
and  bears  a  closer  resemblance  to  human  milk,  while 
even  if  all  the  caseine  is  not  digested,  that  which  remains 
coagulates  in  loose  flakes.     Hence  a  digested,  or  easily 
digestible,  caseine  results  from  this  process.    As  milk  pep- 
tone has  a  bitter  taste,  it  is  as  well  not  to  completely 
transform  the  caseine.     This  artificial  digestion  of  milk 
is  effected  by  means  of  an  extract  of  pancreas.      Dr.  WiU 
liam  Roberts  has  tabulated  four  ferments  as  b^tng  pre- 
sent in  the  pancreatic  juice — trypsin,  curdling  ferment, 
pancreatic  diastase,  and  emulsive  ferment.      The  trypsin 
changes  proteids  into  peptones  in  neutral  or  alkaline 
media,  and  thus  for  practical  purposes  of  artificial  diges- 
tion, especially  in  reference  to  milk,  has   a  great  ad- 
vantage over  pepsine,  which  is  only  ix)tent  through  the 
interaction  of  an  acid.     The  caseine  in  the  cow's  milk  is 
altered   and  partially   or    completely  digested    by   the 
trypsin  ;  hence  any  preparation  of  pancreas  that  does  not 
contain  this  ferment  in  an  active  condition  will  be  useless 
for  peptonizing  milk.     Now  that  a  reliable   extract  of 
pancreas  can  be  obtained,  this  element    of  uncertainty 
is  obviated.     It  may  be  asked  whether  the  practical  re- 
sults of  peptonizing  the  caseine  of  cow's   milk  are  as 
beneficial  in  early  infancy  as  the  theory  would  indicate 


July  5,  1884.] 


THE  MEDICAL  RECORD. 


15 


As  far  as  tried  this  question  can  be  answered  in  the  af- 
firmative. 

Professor  J.  Lewis  Smith  has  the  credit  of  instituting 
a  series  of  trials  at  the  Foundling  Asylum  which  have 
thus  far  given  satisfactory  results,  and  he  considers  that 
peptonizing  milk-  promises  to  mark  an  advance  in  infant 
diet.  We  have  thus  seen  that  cow's  milk  itf  the  best 
substitute  for  human  milk  ; .  that  the  former  is  apt  to  dis- 
agree with  the  infant  on  account  of  definite  chemical, 
physical,  and  physiological  differences  that  have  been 
accurately  ascertained,  and  that  we  now  have  the  means 
largely  to  overcome.  Let  ordinary  pure  cow's  milk  be 
diluted  with  water,  that  has  previously  been  boiled  to 
destroy  all  germs,  until  its  percentage  of  albuminoids  has 
been  reduced  to  the  proper  amount.  Next  add  to  it 
enough  cream  to  make  up  the  fat,  and  some  sugar  of 
milk.  Then  peptonize  it  with  reliable  extract  of  pan- 
creas for  the  alteration  of  the  caseine,  and  there  is  pro- 
I  duced  the  best  physiological  imitation  of  mother's  milk. 
The  peculiar  vital  or  maternal  properties  of  human  milk 
must  always  elude  analysis,  but  to  this  limit  we  have 
well-nigh  reached.  Science,  as  always,  stops  before  the 
mystery  of  vitality. 


AN  ENGLISH  VIEW  OF  THE  MORAL  TENDENCY  OF  THE 
AMERICAN  DOCTOR. 

The  Lancety  in  discussing  the  subject  of  the  American 
Medical  Association,  takes  the  trouble  to  inform  its  read- 
ers  that  *^  there  is  a  natural  tendency  in  a  y^ty  demo* 
cratic  country  Hke  America  to  demand  that  one  man 
shall  be  considered  as  good  as  another,  •  .  .  and  to 
obliterate  the  traditional  morality  which  enjoins  modesty 
of  professional  pretension  and  forbids  the  use  of  unworthy 
means  for  acquiring  reputation  and  practice."  Without 
stopping  to  demonstrate  more  clearly  this  relation  between 
democracy  and  immoral  pretensions,  information  is  then 
pren  as  to  who  a  homoeopath  is,  why  he  should  not  be 
met  in  consultation,  and  finally  the  American  profession 
is  told  that  they  '*  will  have  a  rough  time  of  it  if  they  do 
not  stoutly  maintain  the  principles  "  that  are  editorially 
indicated. 

Thanks,  awfidly.  But  our  esteemed  contemporary,  if 
correct  in  discovering  our  moral  tendency,  at  least  mis- 
apprehends the  real  issue  before  us,  and  leads  its  readers 
to  infer  that  our  moral  degeneracy  will  be  checked  if  we 
Rfose  to  consult  with  irregulars.  Now  those  who  are 
referred  to  as  <<  persons  that  ought  to  know  better,*'  ap- 
preciated long  ago  that  there  was  some  kind  of  a  tendency 
in  the  profession  not  entirely  praiseworthy,  and  saw  that 
somethmg  was  needed  to  check  it,  since  existing  codes 
did  not  For  one  thing,  a  code  was  drawn  up  which 
forbade  advertisements,  and  which  tried  to  substitute  in- 
diridoal  liberty  and  responsibility  for  a  restriction  that 
bad  been  long  violated  and  dead.  But,  besides  this,  on 
an  sides  there  has  been  an  attempt  to  reform  medical  ed- 
ucation, an  attempt  deprecated  as 'Wulgar  ^  in  certain 
Sections,  but  now  warmly  seconded  by  the  mass  of  the 
profesaon. 

The  true  issue  to-day  in  America,  as  we  would  inform 
oar  didactic  contemporary,  is  the  educational,  and  coin- 
cidentally  moral,  elevation  of  the  profession.  For  this 
we  are  striving,  and  we  shall  indeed  '^  have  a  rough  time 
of  it"  if  this  is  neglected.     A  profession  carefully  edu- 


cated, and  composed  of  men  who  have  had  some  moral 
training,  will  be  certain  to  spurn  quackery  and  fraud ; 
and  the  question  whether  a  man  shall  be  at  liberty  to 
consult  with  whom  he  pleases  becomes  a  pitiful  side- 
issue. 


A   CRITICISM    OF    THE    DEATH-RATE   IN    NEW   YORK 
CITY. 

A  CERTAIN  writer  of  the  British  [medical  press  seems 
anxious  to  do  the  people  of  this  city  a  great  statistical 
injustice.  He  has  taken  the  pains  to  prove  to  the  satis- 
faction of  his  unbiassed  and  cosmopolitan  mind  that  the 
population  of  New  York  is  now  only  a  million  instead  of 
a  million  three  hundred  and  fifty-five  thousand,  as  our 
Board  of  Health  fondly  believes,  and  that  consequently 
we  are  dying  one  per  cent,  faster  than  has  been  sup- 
posed, and  is  weekly  reported.  The  true  mortality  rate, 
says  this  correspondent,  is  34.01,  or  more,  per  1,000,  in- 
stead of  25.19,  as  officially  given.  If  this  charge  be 
true.  New  York  is  one  of  the  unhealthiest  cities  in  the 
world,  and  our  city  Board  of  Health  is  shamelessly  de- 
ceiving the  people. 

The  reasons  given  by  the  critic  referred  to  are  as  fol- 
lows. He  writes,  speaking  of  the  alleged  great  increase 
in  the  city's  population  : 

"  It  is  fair  to  assume  that  the  residents  in  New  York 
h^ve  increased  since  1880,  but  not  in  the  ratio  indi- 
cated. That,  however,  I  will  pass  by.  The  fict  that 
the  census  return  is  inaccurate,  and  in  excess  of  the 
truth,  is  more  important.  In  the  United  States  the  cen- 
sus  is  not  taken  as  it  is  in  England  No  day  is  fixed. 
On  the  last  occasion  it  required  foturteen  months  to  get 
the  returns  in.  Many  of  the  persons  whose  names  go 
on  the  census  from  their  places  of  business  in  the  city 
are  non-residents,  and  they  are  put  on  record  again  in 
Brooklyn,  or  New  Jersey,  or  Stalen  Island,  or  wherever 
they  happen  to  live.  I  and  my  family  were  among  the 
large  number  who  were  taken  twice  at  the  last  census. 
Twenty-four  per  cent,  of  the  members  of  the  Stock  Ex- 
change are  non-resident.  In  the  Cotton  Exchange  the 
numbers  are  about  the  same.  In  the  Produce  Exchange 
sixty  per  cent,  of  the  members  live  out  of  town.  The 
resident  population  of  New  York  does  not  exceed 
x,ooo,ooo.     I  doubt  if  it  is  so  much.'' 

He  then  proceeds  to  make  another  estimate  based 
upon  the  registration  of  voters.  The  total  number  regis- 
tered in  1883  was,  he  states,  182,531 ;  multiplying  this  by 
five,  we  get  only  912,655  as  the  total  population,  which 
is  nearly  half  a  million  less  than  the  last  estimate 
(1,355,000),  upon  which  our  sanitary  authorities  base 
their  returns. 

We  do  not  propose  to  attempt  to  prove  that  New 
York  is  a  remarkably  healthy  city,  and  has  over  a  million 
of  inhabitants.  We  leave  this  to  our  sanitary  authorities. 
But  we  would  call  attention  to  certain  sources  of  error  in 
onr  critic's  mode  of  calculating.  The  census  is  taken  in 
June,  when  the  swarms  of  tramps  and  vagabonds  which 
infest  the  city  and  swell  its  mortality,  as  well  as  thous- 
ands of  respectable  families  have  left  town  for  the  sum- 
mer. Any  estimate  of  population  based  upon  the 
number  of  registered  voters  is  utterly  unti^stworthy, 
for  reasons  which  American  citizens  very  well  know, 
and  which  need  not  be  entered  upon  here. 


I6 


THE   MEDICAL  RECORD. 


[July  5,  1884. 


New  York  City  receives  a  vast  influx  of  transients,  in- 
cluding immigrants,  of  whom  the  sick  remain  while  the 
well  pass  on.  Consequently  the  death-rate  in  its  in- 
stitutions is  very  large,  amounting  generally  to  one-fifth 
of  the  whole. 

The  causes  of  the  high  and  hypothetical  death-rate 
estimated  as  above  are  asserted  to  be  bad  air,  bad  water, 
bad  food,  bad  drainage,  imperfect  sanitary  measures,  and 
crowded  tenement-houses,  which  we  are  told  exceed  in 
filth  even  the  London  slums.  All  of  which  is  news  that 
ought  to  be  gratefully  received  by  our  sanitary  authori- 
ties, whose  eyes  have  heretofore  been  blinded  by  a  mis- 
taken patriotism  and  a  desire  to  make  a  good  showing  to 
the  people. 

Finally,  says  The  Lancet  correspondent,  the  great  mor- 
tality is  due  "last,  but  not  least,  to  the  inefficiency  of 
medical  help.  I  say  it  advisedly,  but  emphatically,  after 
several  years  of  close  observation  in  the  United  States, 
that  the  rate  of  mortality  generally,  as  well  as  in  the 
city,  would  be  very  materially  lowered  if  the  standard  of 
medical  education  were  adequately  raised." 

To  this  we  would  simply  say  that  he  is  probably  in  a 
measure  right ;  yet  the  late  President  of  the  American 
Medical  Association  has  asserted  it  to  be  in  bad  taste, 
if  not  absolutely  vulgar,  to  refer  to  the  fact  that  Ameri- 
can medical  education  is  not  just  what  it  ought  to  be. 


NOTES  ON  SUMMER  VACATIONS. 

We  had  declined  several  excellent  articles  upon  the 
timely  subject  of  doctors  and  summer  vacations.  We 
have,  however,  recently  received  from  various  sources 
several  such  pertinent  letters  regarding  the  relations  of 
summering  physicians  to  patients  and  public  that  it  was 
deemed  wise  to  present  them  at  once  to  our  readers. 

The  first  is  from  the  father  of  a  family  who  is  boarding 
at  the  seaside : 

Mr.  Editor,  Dear  Sir  :  I  have  sent  my  family,  con- 
sisting of  my  wife  and  six  children,  to  spend  the  summer 

at .     I  am  paying  ten  dollars  a  week  apiece,  a 

rate  which  is  likely  to  consume  most  of  the  money  I  have 
laid  aside  for  the  summer.  When  I  am  at  home  my 
physician  charges  me  $2  a  visit,  but  last  year  at  the 
sea-shore  1  was  charged  $5,  which  included  social 
calls  and  several  bouquets  for  my  wife.  Will  you  kindly 
use  your  influence  to  persuade  the  summer-seaside  phy- 
sician to  be  more  reasonable  in  his  charges  and  leave  me 
a  little  money  with  which  to  move  back  to  town  in  the 
fall  ?  Very  truly  yours.  Paterfamilias. 

Another  is  from  a  lady  in  the  city : 

Dear  Mr.  £Dnx>R:  I  expect  to  be  confined  about 
the  middle  of  August.  My  family  physician  is  obliged 
to  go  to  Europe  this  summer  to  study,  and  all  his  acquaint- 
ances will  be  in  the  Adirondacks  at  that  time  for  their 
health.  I  know  of  no  physicians  who  will  be  in  town 
then,  except  a  few  homoeopaths  and  the  members  of  the 
Assistant  Sanitary  Corps.     What  am  I  to  do  ? 

Sincerely  yours,  — : . 

A  third  is  from  a  local  physician  at  a  fashionable  health 
resort  in  the  interior : 

Dear  Doctor  :  I  have  a  very  fair  practice  in  this 
town  during  the  year,  but  I  have  until  lately  looked  for- 


ward to  the  summer  months  as  being  especially  useful 
and  lucrative.     For  several   years   past,  however.  Dr. 

A ,  of  New  York,  has  been  up  here  and  taken  all  the 

gynecology.  Dr.  B has  absorbed  the  ear,  eye,  and 

throat  cases,  and  this  year  I  learn  that  Dr.  C is  ex- 
pecting to  be  here  to  attend  to  obstetrical  cases  and 
nervous  exhaustion.  It  seems  to  me  that  this  is  hardly 
fair,  as  I  believe  that  I  have  been  quite  successful  with 
visiting  invalids  before  and  only  charged  one-third  as 
much.  But  I  am  not,  unfortunately,  a  New  York  or  a 
Philadelphia  professor.  Can  you  not  secure  a  little  jus- 
tice to  us  rural  doctors  ? 

Yours  very  truly, ,  M.D. 

Finally  we  have  received  the  following  curious  letter 
from  the  proprietor  of  a  large  seaside  hotel : 

Dear  Sir  :  I  wish  to  secure  a  physician  to  reside  at 
my  hotel  during  the  summer,  and  I  beg  for  your  advice 
in  getting  one  who  will  be  a  little  more  satisfactory 
to  my  guests  in  certain  respects  than  those  who  have 
heretofore  been  established  with  me.  The  medical  gentle- 
men previously  here  have  all  been  of  excellent  manners 
and  fine  professional  attainments,  but  their  charges  have 
been  enormous,  even   compared  with    my  own.     Dr. 

X ^  who  was  here   last  year,  charged  Mrs.  L 

$5  for  brushing  by  her*  on  the  piazza,  and  $10  for 
putting  her  baby  in  the  omnibus.  As  he  danced  several 
times  with  her  daughter  she  could  not  refuse  to  pay. 
But  such  things  are  making  my  hotel  unpopular  with 
invalids. 

Can  you  suggest  some  competent  man  who  charges 
moderately? 

Very  respectfully  yours, , 


The  Cholera  in  Europe. — The  progress  of  cholera 
at  Toulon  may  be  best  seen  by  the  following  table,  show- 
ing the  number  of  deaths  since  the  disease  was  first 
noticed,  June  14th  :  June  14th,  death  i ;  June  19th, 
death  i;  June  20th,  deaths  2;  June  21st,  deaths  3; 
June  22d,  deaths  13 ;  June  23d,  deaths  5  \  June  24th, 
deaths  12 ;  June  25th,  deaths  9;  June  26th,  deaths  10; 
number  of  cases,  62;  June  27th,  deaths  4;  June  28th, 
deaths  6.  On  June  29th,  two  cases  of  apparent  cholera 
were  reported  at  Marseilles  ;  on  the  next  day  five  deaths 
from  the  disease  were  reported.  A  case  was  also  reported 
at  Saluzzo,  Italy,  on  the  30th.  The  opinion  so  far  con- 
tinues to  be  that  the  disease  is  undoubtedly  Asiatic  cholera. 
The  form  of  the  disease  was  at  first  reported  to  be  mild. 
A  great  deal  of  alarm  has  been  excited  throughout  Europe. 
Extraordinary,  and  in  some  cases  foolish,  precautions  are 
being  taken  to  prevent  the  spread  of  the  disease.  The 
roads  and  passes  in  France  leading  from  Toulon  have, 
it  is  said,  been  narrowly  guarded.  Spain  has  established 
a  military  cordon  along  its  frontier.  Quarantine  against 
vessels  from  French  Mediterranean  ports  has  been  estab- 
lished at  Madrid,  Trieste,  Gibraltar,  and  other  ports.  A 
medical  inspection  of  railway  passengers  from  Southern 
France  has  been  established  in  Italy,  Austro-Hungary, 
and  other  places.  Professor  Virchow  takes  the  oppor- 
tunity to  blame  the  French  Government  for  careless 
sanitary  measures.  Toulon  appears  certainly  to  have 
been  a  very  dirty  place,  but  Marseilles  was  reported  clean 
I  and  healthful  at  the  time  the  cholera  appeared. 


ju]y5,i884.] 


THE  MEDICAL  RECORD. 


17 


Itvos  of  tlbe  WSizzk. 


St.  John's  Guild. — ^This  excellent  organization,  that 
has  been  in  existence  since  1866,  hopes  to  continue  its 
excttrsions  this  summer  for  the  benefit  of  sick  children, 
yst  summer  the  floating  hospital  made  32  regular  ex- 
oirsionsand  12  extra  excursions,  carrying  29,189  chil- 
dren and  mothers  or  guardians.  The  sea-side  nursery 
also  did  good  work  in  keeping  children  for  several  days 
m  a  i^eek  in  the  country.  Many  children  with  diarrhoeal 
(gseases  had  their  lives  saved  in  this  manner.  Money  is 
needed  to  cany  on  this  work,  that  commends  itself  to  all 
charitable  persons. 

The  State  Board  of  Health  has  discharged  its  corps 
of  experts  engaged  to  examine  into  adulterations  in  food 
and  drugs,  owing  to  lack  of  funds* 

Nbw  Asylum  for  the  Chronic  Pauper  Insane. — 
The  Commissioners  of  Charities  and  Correction  have 
bought  a  tract  of  land  of  1,067  acres  on  Long  Island,  be- 
tween West  Deer  Park  and  Farmingdale.  They  intend 
to  erect  upcm  it  buildings  for  the  chronic  incurable  pau- 
per insane. 

The  Sundry  Civil  Appropriation  Bill,  as  reported 
to  and  passed  by  the  House,  provides  for  a  repeal  of  the 
Jar  creatmg  the  National  Board  of  Health. 

The  Medical  Register  of  New  York,  New  Jersey, 
AND  Connecticut  for  1884-85^  which  has  just  been  pub- 
lished, contains  the  names  of  6,247  physicians.  Of  these 
the  New  York  State  list  contains  2,686  against  2,684  ^^^ 
year,  and  the  New  York  City  list  1,789  names  against 
1,661  in  the  previous  year.  The  number  registered  in 
the  State  at  large,  therefore,  has  decreased;  that  in 
the  dty  increased. 

The  Worthy  and  Suffering  Poor  of  this  city  have 
only  twenty-five  dispensaries  out  of  which  to  select  their 
medical  and  surgical  attendants.  We  chronicle  with 
pleasure,  therefore,  the  organization  of  the  Good  Samari- 
tan Dispensar3r,  which  is  ^  to  give  medical  aid  to  the  in- 
digent,"  thereby  supplying  a  long-felt  want. 

The  Summer  Sanitary  Corps  of  physicians  has  been 
appointed,  and  report  for  duty  July  6th. 

The  Garfield  Memorial  Hospital,  Washington, 
D.  C.y  opened  on  June  i8th  for  the  reception  of  pa* 

tiats. 

The  Cattle  Disease  in  Kansas  and  Illinois. — 
Rrofessor  James  Law  has  made  an  elaborate  report  upon 
the  disease  which  appeared  last  winter  and  spring  among 
the  cattle  in  Kansas  and  Illinois.  He  concludes  that  the 
animals  suffered  from  dry  gangrene,  the  result  of  eating 
eigoted  hay  and  corn.  Professor  Law's  report  contains 
a  Taluable  review  of  the  subject  of  ergotism  in  cattle. 

The  Vote  to  Admit  Women  into  the  Massachu- 
srrrs  State  Medical  Society  has  led  the  Boston  Medi- 
id  and  Surgical  Journal  vaxx>  the  expression  of  certain 
atiabilioas  Anglicisms.  It  refers  to  the  practice  of  medi- 
cine by  women  as  a  '^  foolish  fad."  Many  will  believe  this 
to  hit  the  case  exactly ;  but  they  must  admit  also  that 
something  has  to  be  conceded  to  abstract  justice,  the 
vomarried  legion,  and  social  peace. 


Other  Discoverers  of  the  Cholera  Bacillus. — 
It  is  reported  that  Dr.  Carter,  Acting  Principal  of  the 
Grant  Medical  College  at  Bombay,  has  found  the  cholera 
bacilli  in  the  perfectly  fresh  dejecta  of  cholera  patients. 
Dr.  Weir,  of  Bombay,  has  found  the  same  bacilli  in  the 
well-water  drank  by  cholera  patients. 

Professor  William  Pepper  has  succeeded  Professor 
Still6  at  the  UniveVsity  of  Pennsylvania,  instead  of  at 
the  Jefferson  Medical  College  as  stated. 

Dr.  Yeng  Tis  Hing. — On  the  recommendation  of 
Dr.  Woolsey  Johnson,  Yeng  Tis  Hing,  a  Chinaman,  was 
recently  registered  as  a  practising  physician  at  the 
Board  of  Health.  It  remains  to  be  seen  whether  he  is 
Old  Code  or  New  Code. 

Bequests  to  Medical  Charities  and  to  Harvard 
Medical  College. — The  late  Samuel  W.  Swett  left  in  his 
will  a  bequest  of  $50,000  for  the  Massachusetts  General 
Hospital,  to  establish  a  convalescent  department;  $10,- 
000  to  the  Children's  Hospital  of  Boston ;  $10,000  to 
the  New  England  Hospital  for  Women  and  Children ; 
$20,000  for  the  Medical  Department  of  Harvard  College. 

Deaths  jn  a  Foundling  Asylum. — Somewhat  sensa- 
tional accounts  are  given  in  the  daily  papers  of  a  found- 
ling home  which  was  opened  last  January,  at  Hammon- 
ton,  N.  J.,  under  the  charge  of  a  Miss  Niverson.  Twenty- 
three  infants  from  Philadelphia,  New  York,  and  elsewhere 
were  brought  to  the  institution.  It  is  stated  that  all  but 
two  of  these  have  died,  not  having  received  meanwhile 
pioper  medical  attendance.  The  New  Jersey  Health 
Board  will  investigate  the  matter.  The  deaths  occurred 
chiefly  from  measles. 

Medical  Instruction  in  Japan. — A  meeting  under 
the  auspices  of  a  committee  of  gentlemen  consisting  of 
Bishop  Stevens,  Drs.  D.  Hayes  Agnew,  William  Pepper, 
and  others,  was  held  in  Philadelphia,  June  12  th,  for  the 
purpose  of  inaugurating  a  movement  looking  to  the  estab- 
lishment in  Japan  of  a  medical  college,  hospital,  and 
training  school  for  nurses.  The  plan  is  largely  the  out- 
come of  the  efforts  of  Dr.  John  C.  Berry,  formerly  of 
Maine,  but  for  the  past  twelve  years  a  medical  missionary 
in  Japan.  Dr.  Berry  explained  the  project  at  length. 
He  estimated  that  to  establish  a  permanent  endowment 
of  one  professorship  $45,000  would  be  required.  Reso- 
lutions were  adopted  indorsing  the  project,  and  in 
furtherance  of  the  plan  as  contemplated  a  committee 
was  appointed  to  confer  with  similar  committees  in  other 
cities  of  this  country. 

The  International  Medical  Congress. — We  have 
received  the  programme  of  the  eighth  session  of  the  In- 
ternational Medical  Congress  to  be  held  in  Copenhagen, 
August  8  to  i6y  1884.  All  medical  men  legally  qualified 
to  practise  in  their  respective  countries  are  entitiled  to 
membership  on  paying  the  subscription  fee  of  twenty 
crowns  (Danish),  equivalent  to  $5.50  in  our  money. 
Each  member  will  receive  a  copy  of  the  "  Transactions  " 
when  published.  The  work  of  the  Congress  is  divided 
into  fourteen  sections,  meetings  of  which  will  be  held 
daily  from  10  to  12  and  i  to  3.  The  general  meetings 
will  be  held  each  day  from  4  to  5.30,  and  in  addition 
some  address  of  a  more  popular  character  will  be  deliv- 
ered in  the  evening  from  8  to  9.30.     The  official  Ian- 


i8 


THE   MEDICAL  RECORD. 


[July  5.  1884. 


guages  of  the  Congress  are  English,  French,  and  Ger- 
man, but  communications  which  cannot  be  made  in  all 
three  languages  will  be  given  in  French.  The  number 
of  papers  and  communications  prepared  or  announced 
for  delivery  in  the  general  and  sectional  meetings  is  over 
two  hundred  and  fifty.  Members  of  the  Congress, 
through  the  courtesy  of  the  Danish  Government  and  the 
United  Steam  Navigation  Co.,  of  Copenhagen,  will  be 
furnished  with  return  tickets  gratis  from  Copenhagen  to 
the  frontiers  of  Denmark  (Fredericia  or  Kiel).  A  bu- 
reau of  information  for  the  benefit  of  the  members  will 
be  establishe;d  at  the  station  of  the  Korsdr-Copenhagen 
Railway.  All  letters  of  inquiry  in  regard  to  lodgings, 
etc.,  shoul4  be  sent  before  the  end  of  July  to  Professor 
C.  Lange,  Secretary-General,  22  Kronprinsessegade, 
Copenhagen,  K.,  Denmark. 

The  late  Dr.  J.  G.  Adams. — ^At  a  stated  meeting  of 
the  Council  of  the  New  York  Academy  of  Medicine,  held 
June  24,  1884,  the  following  preamble  and  resolutions 
were  unanimously  adopted  : 

Whereas,  The  Council  of  the  New  York  Academy  of 
Medicine  has  heard  with  profound  regret  of  the  recent 
death  of  their  associate,  Dr.  John  G.  Adams,' an  original 
Fellow,  and,  at  the  time  of  his  decease,  Corresponding 
Secretary  of  the  Academy ;  • 

Resolved,  That  the  Council  desire  to  put  on  record 
their  warm  appreciation  of  his  fidelity  to  his  convictions, 
his  genial  friendship,  his  ripe  culture,  his  courtesy,  his 
liberal,  earnest,  and  persistent  interest  in  the  Academy, 
and  of  his  gentlemanly  and  Christian  character. 

Resolved^  That  a  copy  of  the  above  preamble  and 
resolution  be  entered  on  the  minutes,  be  published  in  the 
medical  journals  of  the  city,  and  sent  to  his  relatives. 

G.  M.  Smith,'M.D., 
H.  T.  Hanks,  M.D., 

Committee. 
The  Late  Dr.  William  Hustace  Hubbard. — 
Whereas,  Dr.  William  Hustace  Hubbard,  a  late  member 
of  the  house-staff  of  Bellevue  Hospital,  has  been  removed 
by  death,  in  the  beginning  of  his  professional  career ; 
therefore, 

Resolved,  That  this  board  now  expresses  its  apprecia- 
tion of  his  manifest  sterling  qualities  as  a  man,  and  of  his 
faithfulness  and  earnestness  in  his  professional  work ;  also, 
Resolved,  That  in  the  death  of  Dr.  Hubbard  we  have 
lost  a  worthy  assistant,  and  the  profession  at  large  a  most 
promising,  able,  and  upright  member. 

Resolved,  That  we  tender  our  heartfelt  sympathies  to 
his  respected  father  Dr.  Samuel  T.  Hubbard. 

W.  Gill  Wylie,  M.D., 
A.  Brayton  Ball,  M.D., 
George  L.  Peabody,  M.D. 

Committee, 
Another  Microbe  is  Born. — It  was  discovered  and 
cultivated  by  M.  Duclaux.  It  is  that  of  the  disease  known 
as  the  bouton  de  Biskra.  A  patient  from  Tunis  suf- 
fering from  this  affection  was  admitted  to  the  Hospital  St. 
Louis,  where  the  pathology  of  his  condition  was  investi- 
gated. 

Bergh  and  Pasteur.— Mr.  Henry  Bergh,  of  this  city, 
has  sent  some  of  his  ravings,  in  the  form  of  a  letter,  to 
the  President  of  the  Paris  Society  for  the  Prevention  of 


Cruelty  to  Animals*     We  publish  some  of  the  gems  from 
this  letter.     Mr,  Bergh  writes:  "But,  revolting  as  are 
these  canine  massacres,  they  fall  far  short  of  the  barbarities 
of  M.  Pasteur,  both  in  their  atrocity  and  in  the  fatal  conse- 
quences  to  the  physical  as  well  as  moral  well-being  of  the 
French  nation.    In  the  outraged  name  of  science  this  mer- 
ciless empiric  is  poisoning  the  flocks  and  herds  of  France, 
after  the  fashion  of  his  predecessor,  the  notorious  Jenncr, 
of  England,  who  nearly  a  century  ago  commenced  inoc- 
ulating his  countrymen   with  a  noxious  mucus  taken 
from  diseased  animals,  under  the  pretence  of  preventing 
and  curing  small-pox.    That  the  human  race,  through  the 
unfortunate,  existence  of  Jenner,  has  been  hopelessly  de- 
teriorated ;  that  scrofula,  cancer,  and  consumption,  along 
with  their  hideous  long  trains  of  chronic  diseases,  is  the 
fearful  legacy  of  that 'man's  presence  on  earth,  some  of 
the  most  learned  and  conscientious  scientists  have  de- 
clared to  be  their  belief,     A  French  Jenfter  now  crawls 
to  the  earth's  surface  and  begins  the  fiend-like  and  dis- 
gusting work  of  polluting  the  bodies  and  flesh  of  the  lower 
animals  I     Moreover,  it  is  proposed  in  the  Chamber  of 
Deputies  to  reward  this  man's  detestable  crime  by  voting 
him  a  pension  also." 

Death  from  Chloroform  given  in  Child-birth. 
— ^A  death  under  chloroform  occurred  recently  at  St, 
Bartholomew's  Hospital,  attended  by  circumstances  ot 
an  unusual  character.  The  patient  was  a  woman  seven 
and  a  half  months  pregnant,  who  had  been  admitted  into 
hospital  on  account  of  placenta  praevia.  On  the  day 
preceding  the  fatality,  chloroform  had  been  taken  by  the 
woman  without  any  symptoms  indicative  of  danger  ;  but 
soon  after  the  second  administration  was  commenced, 
respiration  and  pulse  became  suspended,  and  death  was 
unmistakable. 


©Mtuat^B- 


JOEL  FOSTER,  M.D., 

NEW  YOUC* 

Dr.  Joel  Foster,  one  of  the  oldest  practising  physicians 
in  this  city,  died  on  June  29th.  He  had  been  ill  for 
about  a  month  and  a  half,  but  was  not  confined  to  his 
bed  until  a  week  prior  to  his  death.  Then  he  sank 
gradually,  and  expired  at  an  early  hour  on  the  above- 
mentioned  date.  He  was  born  in  Barnard,  Vt.,  March 
10,  1802.  His  ancestors  were  among  the  original  settlers 
of  Vermont  and  figured  in  the  French  war,  and  he  was 
also  a  distant  relative  of  General  Stark,  of  Revolutionary 
fame.  He  first  studied  medicine  in  Woodstock,  Vt., 
under  Dr.  Gallop,  and  afterward  removed  to  Philadel- 
phia, where  he  resumed  his  studies  in  Jefferson  College. 
Here  he  graduated  with  the  highest  honors. 

After  securing  his  diploma  he  married  and  began  his 
work  as  a  physician  in  Schoharie,  N.  Y.  In  1855  he 
came  to  this  city,  and  since  that  time  has  been  busily 
engaged  in  his  practice.  When  the  President  called  for 
volunteer  physicians,  after  the  second  battle  of  Bull  Run, 
Dr.  Foster  secured  thirty-seven  doctors  from  the  Acad- 
emy of  Medicine  in  this  city  and  started  for  the  field. 
He  did  good  service  in  administering  to  the  wants  of  the 
wounded,  and  gained  honorable  mention  for  his  work  in 
this  respect.  Dr.  Foster  was  the  oldest  life  member  of 
the  State  Medical  Society,  and  was  one  of  the  founders 
of  the  Academy  of  Medicine  in  this  city.  He  was  also 
prominently  identified  with  the  Infant  Asylum.  He  was 
a  prominent  and  active  abolitionist  and  was  a  friend  of 
William  H.  Seward. 


July  5,  1884.] 


THE   MEDICAL  RECORD. 


19 


"^jmievoa  aud  ^ottcjes. 


DUGNOSIS     AND     TREATMENT     OF     DISEASES     OF     THE 

Heart.  By  Constantine  Paul,  Member  of  the 
Academy  of  Medicine,  Physician  to  the  Lariboisiere 
Hospital.     New  York  :  William  Wood  &  Co.     1884. 

Dr.  Paul's^  treatise  on  cardiac  affections,  which  is  the 
March  number  of  Wood's  Library,  is  a  systematic  and 
practical  exposition  of  this  interesting  and  important 
dass  of  affections.  In  all  that  relates  to  etiology, 
symptomatology,  and  diagnosis,  we  know  of  no  better 
work.  In  the  chapter  on  treatment  we  miss  that  detailed 
account  of  what  is  at  present  known  with  regard  to  the 
therapeutics  of  the  various  stages  of  cardiac  diseases  that 
one  might  expect  in  a  special  work  of  this  kind.  In  spite 
of  this  drawback,  however,  the  work  well  repays  a  care- 
ful perusal. 

Post-Nasal  Catarrh  and  Diseases  of  the  Nose 
causing  Deafness.  By  Edward  Woakes.  IUus- 
trated  with  Wood  Engravings.  Pp.  224.  Philadel- 
phia :  P.  Blakiston,  Son  &  Co.     1884. 

This  interesting  volume  is  intended  to  show  the  relations 
that  exist  between  that  portion  of  the  upper  air  tract  em- 
braced in  the  nasal  region  and  the  organ  of  hearing.  It 
would  seem  from  the  point  of  view  taken  by  the  author 
that  the  otologist  must  seek  for  the  cause  of  many  aural 
Symptoms  in  the  nervous  relationship  known  to  exist  be- 
tween the  different  regions  about  the  head,  especially 
those  between  the  naso-pharynx  and  the  ear.  The  ex- 
tension of  catarrhal  inflammation  from  the  pharyngeal 
Tault  to  the  ear,  via  the  Eustachian,  thus  seems  no^  to  be 
the  principal  cause  of  ear  disease,  as  some  have  sup- 
posed. 

While  the  author's  style  is  often  unnecessarily  in- 
volved, and  simple  facts  are  frequently  made  to  appear 
more  obscure  to  the  general  medical  reader  than  needs 
be,  yet,  on  the  whole,  the  subject  is  presented  in  an  enter- 
taining and  instructive  manner.  He  has  brought  into 
the  field  of  otology  the  methods  of  the  study  of  disease 
which  have  been  already  so  successfully  employed  in 
other  departments  of  medicine,  namely,  the  physiologi- 
cal. The  book  may  be  taken,  as  far  as  it  goes,  as  a  safe 
guide  in  the  study  of  aural  neuroses. 

The  present  volume  is  to  some  extent  an  elaboration 
of  a  former  work,  in  which  the  nervous  mechanism  con- 
cerning disturbances  about  the  head,  and  especially  about 
the  ears,  was  discussed.  In  the  introductory  chapter 
there  are  observations  on  the  correlating  and  reflex  func- 
tuHis  of  the  sympathetic  system,  which  will  be  found  to 
be  broadly  instructive,  and  which  go  to  show  that  in  any 
successful  plan  of  treatment  of  aural  diseases  the  load 
medication  must  often  occupy  a  subordinate  position. 

The  second  chapter  treats  of  the  etiology  of  catarrh, 
acate  and  chronic,  and  what  the  author  designates  as  the 
pre-catarrhal  state;  Chapter  III.  discusses  the  mechan- 
^mof  taking  cold;  Chapter  IV.,  chronic  or  post-nasal 
catarrh,    and  its  sequences;   the  hygienic  management 
of  the  catarrhally  predisposed  is  considered  in  Chapter 
V,  ;   the  diagnosis  of  chronic   catarrh,  examination  of 
patients,  etc.,  is  taken  up  in  Chapter  VI.     Other  chap- 
ters are  devoted  to  acute  catarrh,  chronic  pharyngitis, 
and  the  pharyngeal  tonsil — their  pathology  and  treat- 
ment.     Chapters  XI.  aud  XII.  treat  of  nasal  stenosis. 

The  chapter  on  "  taking  cold  "  is  an  admirable  expo- 
sition of  the  subjectp  and  should  be  studied  by  every  one 
who  has  to  treat  nasal  catarrhs. 

Although  the  author  has  made  considerable  additions 
to  the  physiological  aspect  of  the  subject,  pathological 
conditions  are  dwelt  on  more  briefly  than  seems  com- 
mensurate with  the  detailed  consideration  of  the  former. 
Attention  is  given  to  the  treatment  of  nasal  affections, 
a:id  some  useful  suggestions  may  be  found  under  this 
h-^d,    although  the  emplojrment  of  sprays,   the  nasal 


douche,  and  syringe  seem  to  be  recommended  rather 
more  freely  than  would  be  done  by  most  otologists  on 
this  side  of  the  water.  The  treatment  of  aural  affections 
receives  a  share  of  attention,  and  here  Dr.  Woakes  fol- 
lows the  beaten  track*  He  seems  so  be  a  warm  advo- 
cate of  the  early  incision  of  the  drum-head  in  acute  pro- 
cesses affecting  the  middle  ear,  although  recommending 
the  procedure  with  some  appearance  of  caution  ;  this,  to- 
gether with  the  subsequent  free  use  of  the  Politzer  air- 
douche  and  running  hot  water  into  the  ear  seems,  to 
some  of  us  at  least,  rather  heroic.  The  work  on  the 
whole  is  a  valuable  contribution  to  the  subject  of  which 
it  treats,  and  it  should  be  in  the  hands  of  every  specialist 
in  this  department  of  medicine,  as  well  as  every  general 
practitioner. 

Medical  Diagnosis,  with  Special  Reference  to 
Practical  Medicine.  By  J.  M.  Da  Costa,  M.D., 
LL.D.,  Professor  of  Practice  of  Medicine  and  of  Clini- 
cal Medicine  at  the  Jeflerson  Medical  College,  Phila- 
delphia, etc.  Sixth  edition.  Philadelphia:  J.  B. 
Lippincott  &  Co.     1884. 

It  is  pleasant  to  have  to  record  the  appearance  of  a 
new  edition  of  Da  Costa's  well-known  medical  diagnosis. 
The  work  is  thoroughly  appreciated  here,  and  its  trans- 
lation into  foreign  tongues  shows  the  estimation  in  which 
it  is  held  abroad.  The  present  edition  is  fully  up  to 
date,  several  not  unimportant  additions  having  been 
made.  It  is  not  a  work  of  reference,  but  rather  one  that 
should  be  studied  from  beginning  to  end. 

Vorlesungen  tJBER  Pharmakologie.  Von  Professor 
C.  BiNZ,  Ord.  Professor,  Direktor  des  Pharmakolo- 
gischen  Instituts  der  Universitat  Bonn.  I.  Abtheilung. 
Berlin:  Aug.  Hirschwald.  1884.  Lectures  on  Phar- 
macology.    By  Dr.  C.  Binz. 

Professor  Binz,  of  Bonn,  hardly  requires  an  introduc- 
tion to  the  American  reader,  his  original  contributions 
relating  to  pharmacological  subjects  having  been  fre- 
quently noticed  by  the  medical  press  both  of  England 
and  our  own  country.  The  volume  before  us  comprises 
Part  I.  of  the  subject-matter  of  the  lectures  delivered 
annually  at  the  University  of  Bonn.  Two  succeeding 
parts  will  complete  the  work.  The  author  has  a  happy 
faculty  of  infusing  a  new  interest  into  an  habitually  dry 
and  tedious  subject.  In  this  way  the  book  contrasts 
very  favorably  with  the  average  Materia  Medica  and  its 
tiresome  enumeration  of  superfluous  details.  The  phar- 
macology of  Binz,  judging  from  this  the  flrst  volume,  is 
practiced  and  yet  strictly  scientific,  clear  and  concise,  and 
yet  complete  enough  to  satisfy  the  demands  both  of  stu- 
dent and  practitioner.  It  goes  without  saying  that  the 
work  is  fully  up  to  date.  We  believe  that  an  English 
translation  would  find  a  ready  welcome  in  our  country.^  < 

The  Diseases  of  Children.  A  Handbook  for  Prac- 
titioners and  Students.  ByJ  Armand  Semple,  B. A., 
M.B.  Cantab.,  M.R.C.P.  Lond.  Pp.  352.  New  York : 
G.  P.  Putnam's  Sons.     1884. 

This  is  a  small  volume,  and  presents  the  subject  j  of 
paediatrics  in  a  more  condensed  form  than  is  the  case 
with  the  usual  treatises.  The  volume  does  not  strike  us 
as  having  any  great  merit  aside  from  its  compactness. 
There  is  no  evidence  of  originality  in  thought  or  method, 
and  we  should  doubt  if  Mr.  Semple  had  had  a  long  ex- 
perience with  children's  diseases. 

In  this  respect  it  is  in  striking  contrast  with  Henoch's 
work.  The  author  also  is  not  entirely  free  from  mis- 
leading statements,  as  when  he  describes  croupous  pneu- 
monia, leaving  one  to  infer  that  it  may  attack  children  at 
any  age,  and  independently  of  broncho-pneumonia. 

For  all  this,  however,  the  book  is  a  very  fair  presenta- 
tion of  its  subject,  and  is  in  the  main  trustworthy.  It  is 
clearly  written  and  systematically  arranged.  The  pub- 
lishers have  printed  it  in  excellent  style. 


20 


THE  MEDICAL  RECORD. 


[July  5, 1884. 


Medical  Annals  of  Baltimore.    From  1608  to  1880, 
to  which  is  added  a  Subject  Index  and  Record  of 
Public  Services,     By  John  R.  Quinan,  M.D.     Balti- 
more.    1884. 
This  volume  represents  a  great  deal  of  painstaking  labor, 
and  will  be  of  much  local  interest  and  value. 

Transactions  of  the  New  York  Pathological  So- 
ciety.    Vol.  IV.     Based  on  the  Proceedings  of  the 
Year  188 1,  and  Supplemented  from  the  Records  from 
1844.     John  C.  Peters,  M.D.,  Editor.     New  York: 
Printed  for  the  Society.     1882. 
The  New  York  Pathological  Society  is  one  of  the  best 
medical  societies  in  this  city.     Founded  forty  years  ago 
for  "  the  improvement  of  its  members  in  pathology,  and 
in  the  diagnosis  and  treatment  of  disease  as  founded  on 
pathology,"  it  has  ever  held  this  object  prominently  in 
view,  and  that  it  has  lost  none  of  its  original  fervor  in 
the  advancement  of  medical  science  this  present  volume 
of  the  Transactions  bears  abundant  testimony.      The 
book  is  neatly  printly  and  strongly  bound,  and  contains 
more  matter  of  solid  worth  in  its  380  pages  than  many  a 
more  pretentious  tome. 

The  Medical  Directory  of  Philadelphia  for  1884. 

Edited  by  Samuel  B,  Hoppin,  M,D.     Philadelphia : 

P.  Blakiston,  Son  &  Co.  1884. 
This  little  volume  contains,  besides  the  list  of  the  regu- 
lar physicians  of  Philadelphia,  the  names  of  all  the 
homoeopathic  and  eclectic  practitioners,  and  of  persons 
practising  medicine  without  diplomas,  but  registered 
under  the  laws  of  the  State.  There  are  also  lists  of 
druggists,  dentists,  and  graduates  of  recognized  veterinary 
colleges,  as  well  as  non>graduate  veterinary  surgeons 
and  dentists. 

The  General  Practitioner's  Guide  to  Diseases  and 
Injuries  of  the  Eye  and  Eyelids.     By  Louis  H. 
TosswiLL,  B.A.,  M.R  Cantab.,  M.R.C.S.,  Surgeon  to 
the  West  of  England  Eye  Infirmary  at  Exeter.     Lon» 
don  :  J.  &  A.  Churchill.     1884. 
The  author's  aim  in  writing  this  little  book  was  to  give 
to  the  general  practitioner  a  manual  to  which  he  might 
refer  for  guidance  in  the  diagnosis  or  management  of  the 
more  common  diseases  and  injuries  of  the  eye.     And  he 
has  succeeded  admirably  in  his  attempt.     The  book  is  a 
model  of  brevity  and  clearness  of  description,  and  is  en- 
tirely free  from  the  technical  terms  and  mathematical 
problems  which  are  usually  so  confusing  to  the  ordinary 
reader  of  works  on  ophthalmology. 

Diseases   of  the   Bladder,  Prostate  Gland,  and 
Urethra.     Including  a  Practical  View  of  Urinary 
Diseases,  Deposits,  and  Calculi.     Illustrated  by  Nu- 
merous Wood  Engravings.    Fifth  Edition,  Revised  and 
much   Enlarged  throughout.     By  Frederick  James 
Gant,  F.R.C.S.,  Late  President  of  the  Medical  So- 
ciety of  London  ;  Senior  Surgeon  to  the  Royal  Free 
Hospital;  Author  of  "The  Science  and  Practice  of 
Surgery."     New  York  :  Bermingham  &  Co.     1884. 
This,  the  fifth,  edition  of  Mr.  Gant's  well-known  treatise 
on  diseases  of  the  bladder  and  neighboring  organs  comes 
to  us  greatly  enlarged  and  revised.     Every  chapter,  in- 
deed almost  every  page,  shows  marks  of  improvement, 
and  of  such  changes  as  were  necessary  to  be  made  in 
order  to  maintain  the  character  of  the  work  as  a  thor- 
oughly reliable  guide  for  the  surgeon  in  dealing   with 
these  affections.     The  author  treats  not  only  of  the  or- 
dinary and  more  common  diseases  of  these  organs,  but 
enters  also  somewhat  at  length  into  the  exceptional  cir- 
cumstances in  which  the  surgeon  may  be  placed,  and 
sets  down  rules,  as  far  as  rules  can  be  thus  set  down,  for 
his  guidance  in  all  the  straits  in  which  he  may  find  him- 
self.    Somewhat  over  one  hundred  out  of  the  six  hun- 
dred pages  of  the  book  are  devoted  to  the  consideration 
of  urinary  diseases  and  of  the  nature  of  the  deposits  in 
this  fluid.     While  the  author  presents  in  his  work  but 


little  that  is,  strictly  speaking,  new,  or  which  may  notjbe 
found  in  one  or  another  of  the  treatises  upon  the  sub- 
jects which  it  embraces,  there  are,  nevertheless,  few  books 
in  which  one  may  find  so  complete  an  exposition  of  all 
diseases  relating  to  the  urinary  organs  as  in  this.  It  is, 
furthermore,  by  no  means  a  mere  compilation,  but  pos- 
sesses that  peculiar  freshness  which  is  a  sure  evidence  that 
the  author  writes  from  personal  knowledge,  and  has  not 
simply  clothed  the  ideas  of  others  in  language  of  his  own. 

A  Study  of  the  Bladder  during  Parturition.  By 
J.  Halliday  Croom,  M.D.,  F.R.C.P.E.,  Physician  to 
the  Royal  Maternity  Hospital ;  Assistant  Physician  for 
Diseases  of  Women,  Royal  Infirmary ;  Examiner  in 
Midwifery  in  the  University,  and  Lecturer  on  Mid- 
wifery and  Diseases  of  Women,  School  of  Medicine, 
Edinburgh.     Edinburgh :  David  Douglas.     1884. 

The  object  of  this  book,  containing  the  substance  of 
several  papers  communicated  to  the  Edinburgh  Obstet- 
rical Society,  is  to  show  the  extent  and  manner  in  which 
the  bladder  and  its  contents  are  influenced  by  parturient 
efforts.  The  author  states  that  the  sources  of  pressure 
upon  the  bladder  are  three :  a.  Change  of  shape  in  the 
uterine  ovoid ;  by  stretching  of  the  cervix ;  ^,  pressure 
by  the  abdominal  and  other  respiratory  muscles,  ^.^., 
diaphragm,  levator  ani,  etc.  The  quantity  of  urine  in 
the  bladder  does  not  influence  pressure,  provided  always 
the  point  of  over-distention  is  not  reached.  The  mini- 
mum pressure  is  found  during  the  first  stage,  and  amounts 
to  .  I  lb.,  while  the  maximum  occurs  during  the  second 
stage,  and  is  about  3.2  lbs.  on  the  square  incli.  The 
work  evidences  a  large  amount  of  painstaking  investiga- 
tion on  the  part  of  the  author,  but  the  subject  is  one  in 
which  the  ordinary  practitioner  would  take  but  a  languid 
interest. 

Beginnings  with  the  Microscope.    A  Working  Hand- 
book, containing  Simple  Instructions  in  the   Art  and 
Method  of  Using  the  Microscope,  and  preparing  Ob- 
jects for  Examination.    By  Walter  P.  Manton,  M.D. 
Illustrated.    Pp.73.    Boston :  Lee  &  Shepard.     1884. 
This  little  book  will  be  found  y^ry  useful  for  beginners 
in  microscopical  study,  who  are  often  appalled  by  the 
size  of  the  standard  treatises  on  this  subject.    The  author 
has  here  given  directions  for  the  preparing,  staining,  and 
mounting  of  the  objects  to  be  examined,  such   as  are 
needed  by  those  who  have  had  little  or  no  experience  in 
microscopical   work.     For  advanced  students    it   is   of 
course  too  elementary,  but  for  beginners  it  is  eminently 
practical,  and  may  serve  as  an  introduction  to  the  larger 
works. 

The  London  Pathological  Society. 

The  thirty-fourth  volume  of  the  Transactions  of  this 
Society  is  before  us.  Perhaps  our  own  Society  may  get 
some  hints  from  it.     It  was  founded  in  1846,  and  ours  in 

1844.  Its  presidents  always  serve  two  years,  ours  gen- 
erally only  one.  Its  first  president,  in  1846,  was  Charles 
J.  B.  Williams,  ours  was  Willard  Parker,  in  1845,  although 
Dr.  John  A.  Swett  served  as  chairman  for  six  months  in 

1845.  ^^  other  presidents  have  been  Charles  Aston  Key, 
Peter  Mere  Latham,  Caesar  N.  Hawkins,  Benjamin  Guy 
Babbington,  James  M.  Amott,  Sir  Thomas  Watson,  Sir 
William  Ferguson,  James  Copland,  Sir  Prescott  G. 
Hewitt,  Thomas  B.  Peacock,  John  Simon,  Richard 
Quain,  John  Hilton,  Sir  William  Jenner,  George  D. 
Pollock,  Charles  Murchison,  Jonathan  Hutchinson, 
Samuel  Wilks,  John  W.  Hulk.  It  always  has  eight  vice- 
presidents,  nine  surgical  councillors  and  nine  medical, 
none  of  whom  are  vice-presidents ;  two  honorary  secre- 
taries, one  medical  the  other  surgical ;  two  trustees, 
and  one  treasurer.  The  whole  number  of  members  in 
1883  was  650,  and  27  new  members  were  added  during 
the  year. 

Dr.  Peacock,  just  deceased,  generously  bore  the  whole 
cost  of  publishing  and  issuing  a  general  index  to  the 
volumes  from  1864- 18  74,  viz.,  vols,  16-25. 


July  S,  1884.] 


THE  MEDICAL  RECORD. 


21 


Dr.  Edwards  Crisp,  just  deceased,  during  a  long  course 
of  years  insisted  upon  the  advantage  of  studying  the 
morbid  anatomy  of  animals,  and  since  1864  was  continu- 
ally exhibiting  specimens,  which  he  had  procured  from 
the  Zoological  Gardens  and  elsewhere.  Dr.  Crisp  was 
the  pioneer  of  the  .London  Pathological  Society  in  the 
study  of  comparative  pathology,  and  it  must  have  gratified 
him  to  witness  the  establishment  by  the  council,  at  the 
suggestion  of  Dr.  J.  Hutchinson,  of  a  comparative  fpa- 
thology  committee.  Another  committee  has  been  formed 
to  obtain  information  respecting  the  uncompleted  cases 
in  the  Transactions,  which  has  already  reported. 

Owing  to  the  large  number  of  specimens  offered,  a  great 
many  could  not  be  received  on  account  of  the  limit  of 
time  at  the  disposal  of  the  Society,  and  extra  meetings 
are  under  consideration. 

In  1882  there  was  ;^i39  balance  in  the  treasury  ;  four 
hundred  annual  subscriptions  produced  ;^42o ;  twenty- 
three  admission  fees,  ^£24  ;  two  life  fees,  ;£^i  ;  two  mem- 
hers  in  arrears,  ^£2.  The  sale  of  the  Transactions  to  non- 
members  produced  ^£62,  sale  of  illustrations,  j^iS- 
Total  income,  ;^7o3. 

The  Society  paid  to  the  Royal  Medical  and  Chirur- 
gical  Society  for  use  of  rooms,  gas,  etc.,  j£6;^  ;  refresh- 
ments, waiters,  etc.,  ^^36 ;  for  janitor,  microscopes,  and 
lamps,  ;^i  I ;  for  printing,  binding,  etc.,  of  Transactions, 
;fi94;  for  supplementary  report,  750  copies,  ;^i8 ;  for 
hthography,  woodcuts,  etc.,  j/^126  ;  for  stationery,  ^£1$; 
for  postage,  3  pence  ;  for  secretaries  and  treasurer,  not 
including  stenography,  j£^6 ;  total  expenses,  ;^5o2  ; 
balance  in  treasury,  ^201, 

Opera  Minora  ;  a  Collection  of  Essays,  Articles,  Lec- 
tures, and  Addresses  from  1866  to  1882  inclusive.  By 
Edward  C.  Seguin,  M.D.  New  York:  G.  P.  Put- 
nam's Sons.      1884. 

The  articles  here  collected  make  a  large  quarto  volume 
of  near  seven  hundred  pages.  The  author  modestly  says 
that  "  the  redeeming  feature  in  the  collection  will  per- 
haps be  the  series  of  observed  facts  faithfully  recorded." 
The  volume  has  more  value  than  is  measured  by  such  an 
estimate.  Thejirticles  touch  upon  nearly  the  whole  field 
of  neurology,  and  nearly  every  one  contains  something  of 
interest  or  practical  value.  Expositions  of  nervous 
phjsiology,  contributions  to  neurological  therapeutics,  and 
original  researches  in  pathology— especially  of  the  spinal 
cord— form  the  leading  features  of  a  collection  which 
does  great  credit  both  to  the  author  and  to  American 
science. 

New  York  anb  Brooklvn  Formulary  of  Unofficinal 
Preparations.  Published  by  a  Joint  Committee  of 
Delegates  from  the  College  of  Pharmacy  of  the  City 
of  New  York,  the  New  York  German  Apothecaries' 
Society,  and  the  Kings  County  Pharmaceutical  So- 
ciety. New  York :  Publication  Office,  College  of 
Tbaurmacy  Building. 

The  great  and  increasing  number  of  preparations  of  so* 
called  elegant  pharmacy  is  as  annoying  and  perplexing 
to  the  physician  as  to  the  pharmacist,  and  any  measures 
looking  toward  a  reduction  of  the  number  are  to  be  wel- 
comed. A  committee  of  delegates  from  three  pharma- 
ceutical societies  of  this  city  and  Brooklyn  have  prepared 
a  niunber  of  formulae  for  the  compounding  of  the  more 
commonly  used  elixirs,  emulsions,  and  syrups,  and  it  is 
hoped  that  the  physicians  of  the  two  cities  will  order 
these  preparations  only,  and  not  designate  on  their  pre- 
scriptions those  of  any  particular  house.  Such  a  result 
is  certainly  to  be  desired,  and  perhaps  may  be  obtained 
through  the  wide  distribution  of  this  formulary.  But  the 
drnggists  will  have  to  rise  betimes  in  the  morning  to  score 
a  point  against  the  representatives  of  the  manufacturing 
finns  with  their  smooth  tongues  and  seductive  ways.  If 
Acy  succeed  in  driving  these  gentlemen  from  the  field 
they  will  have  earned  the  gratitude  of  the  entire  profes- 
sion, and  will  no  doubt  receive  their  reward. 


Reports  at  SacietUs. 


MICHIGAN  STATE  MEDICAL  SOCIETY. 

Nineteenth  Annual  Session  held  at  Grand  Rapids^  June 
II  and  12,  1884. 

(Continued  from  No.  34,  p.  671.) 

In  report  of  the  first  day's  proceedings,  by  telegraph,  of 
this  meeting,  abstracts  of  papers  were  omitted. 

Dr.  Donald  Maclean,  Chairman  of  the  Committee 
on  Surgery,  read  an  interesting  reportof  four  cases  which 
had  come  under  his  care  at  the  University  Hospital  clinic. 
The  first  case  was  a  lady  who  presented  symptoms  of 

SYPHILITIC  PERIOSTITIS, 

but  who  gave  none  of  the  early  symptoms  or  any  history 
of  any  syphilis  either  in  her  own  person  or  that  of  her 
husband.  The  diagnosis  seemed  to  rest  between  a  malig- 
nant affection  and  syphilitic  affection.  The  doctor  gave 
her  the  benefit  of  the  doubt,  put  her  on  large  doses 
of  iodide  of  potassium,  and  she  made  a  rapid  and  full 
recovery. 

Some  time  after  she  came  to  the  clinic  again  and  pre- 
sented her  little  son,  about  four  years  of  age.  The  little 
fellow  was  bow-legged,  and  had  exostosis  of  the  upper 
end  of  the  tibia.  This  patient  was  put  on  iodide  of 
potassium  and  is  now  reported  as  quite  recovered.  The 
third  case  was  one  of 

NECROSIS   OF  THE    LOWER    END   OF  THE    FEMUR. 

In  attempting  to  remove  a  large  piece  of  necrosed  bone 
with  the  bone  forceps 

THE    POPLITEAL   ARTERY  WAS   TORN   ACROSS. 

The  hemorrhage  was  arrested  by  pressure  with  the 
fingers;  the  necrosed  bone  was  removed  and  the  pop- 
liteal artery  cut  down  upon  and  ligated  above  and  below 
the  site  of  the  injury.  The  patient  did  well  and  made 
an  excellent  recovery. 

The  fourth  case  was  a  man  of  twenty-eight,  who  in 
jumping  from  a  train  of  cars  in  motion  received  an  in- 
jury on  the  elbow.  The  arm  was  firmly  anchylosed  at 
the  elbow  and  it  was  thought  best  to  resect  the  elbow- 
joint.  A  straight  incision  was  made  along  the  back  of 
the  arm  and  when  the  parts  were  brought  to  view  it  was 
found  that  the 

RADIUS    AND    ULNA    WERE    DISLOCATED    BACKWARD    AND 
SOLIDLY  ANCHYLOSED 

to  each  other  and  to  the  humerus.  About  one  inch  was 
taken  off  firom  the  humerus,  and  about  an  inch  from  the 
ulna  and  radius.  The  patient  made  an  excellent  recovery 
and  has  regained  motion  at  the  elbow  to  a  large  degree — 
that  of  supination  and  pronation.  This  case  is  typical  of 
about  twenty  others  which  the  professor  has  operated 
upon  at  the  hospital  clinic. 

Dr.  Charles  J.  Lundy's  paper  elicited  considerable 
interest.  Dr.  Lundy  said  that  within  a  few  years  the  re- 
sources of  the  aural  surgeon  had  been  greatly  increased, 
both  by  the  introduction  of  new  therapeutic  agents  and 
by  the  use  of  old  ones  in  a  new  way.  In  appropriate 
cases  the 

SO-CALLED    DRY   TREATMENT    OF    CHRONIC    SUPPURATIVE 
OTITIS    MEDIA 

had  proven  highly  beneficial.  All  knew  that  the  disease 
was  attended  with  danger,  and  many  bad  seen  exam- 
ples of  cases,  and  necrosis  of  the  temporal  bone,  mas- 
toid abscess,  meningitis,  cerebral  abscess,  or  death,  which 
occurred  as  the  result  of  neglected  suppurative  otitis  me- 
dia. Therefore  any  system  of  aural  therapeutics  which 
the  better  enabled  us  to  control  and  cure  this  affection 
was  a  great  boon.  Before  beginning  the  use  of  pow- 
ders, all  remediable  complications  must  be  removed. 
If  aural  polypus  or  granulations  be  present  they  must  be 
removed  or  destroyed,  and  so  it  was  also  with  remova- 
ble  pieces  of  necrosed  bone,  in  the  mastoid  or  else- 


22 


THE   MEDICAL  RECORD- 


[July  5,  1884. 


where.  The  advantages  which  the  dry  treatment  of 
chronic  suppurative  otitis  media  seemed  to  offer  were  : 
I,  the  constant  medication  of  the  parts;  2,  the  thor- 
ough and  continuous  disinfection  of  the  ear  as  well 
as  the  destruction  of  micro-organisms;  3,  the  absorp- 
tion of  the  discharges  and  protection  from  their  irri- 
tating properties ;  4,  protection  from  atmospheric  influ- 
ences. Some  space  was  devoted  to  illustration  of  these 
points,  and  while  it  was  not  fully  settled  as  to  which 
of  these  was  the  most  important  advantage  arising 
from  the  use  of  dry  powders,  a  majority  conceded 
that  the  destruction  of  the  micro-organisms  and  the  pro- 
tection from  atmospheric  influences  were  the  strong  argu- 
ments in  favor  of  the  dry  treatment.  It  could  not  be 
claimed  that  powders  should  be  used  to  the  exclusion  of 
remedies  in  other  forms,  and  they  were  counter-indicated 
at  times.  In  certain  cases  they  proved  a  failure,  and 
sometimes  did  harm  instead  of  good.  While  no  definite 
plan  could  be  laid  down  for  the  management  of  individual 
cases,  yet  some  rules  could  be  formulated  for  our  guid- 
ance in  a  general  way. 

The  so-called  dry  treatment  would  seem  to  be  contra- 
indicated  under  the  following  circumstances  :  First,  when 
the  discharge  is  so  profuse  that  the  powder  becomes 
supersaturated  before  it  has  had  time  to  exert  any  bene- 
flcial  influence ;  second,  when  granulations  or  polypi 
exist  the  dry  treatment  should  not  be  employed  until 
these  bodies  have  been  destroyed  or  removed,  although 
powdered  boracic  acid  would  cause  absorption  or  de- 
struction of  these  in  a  few  cases ;  third,  when  the  disease 
is  complicated  by  caries  or  necrosis  of  the*temporal  bone ; 
fourth,  when  mastoid  abscess  is  present  or  suspected ; 
fifth,  when  there  is  good  reason  to  suspect  the  presence 
of  meningeal  or  cerebral  complications.  The  remedies 
which  might  be  used  were  numerous  but  the  author  had 
confined  himself  to  few.  Wyeth's  pure  boracic  acid  was 
free  from  irritating  properties  and  a  favorable  remedy 
with  him.  Boracic  acid,  one  part  with  seven  parts  of 
resorcin,  formed  a  valuable  combination.  Bismuth  and 
perchloride  of  mercury  he  sometimes  used,  especially  if 
eczema  of  the  auditory  canal  existed.  Astringents  could 
be  combined  with  the  boracic  acid  if  desired.  It  was  of 
great  importance  to  cleanse  the  ear  thoroughly  before 
using  the  powders.  After  the  lapse  of  one,  two,  or 
three  days,  when  the  powder  becomes  moist,  it  should  be 
removed,  and  the  ear  filled  with  fresh  powder.  Cases 
were  reported  showing  some  very  remarkable  cures  from 
the  use  of  remedies  in  dry  form,  especially  from  boracic 
acid.     A  paper  on 

EXPERT  TESTIMONY  AND   COMPENSATION, 

from  the  pen  of  Dr.  Samuel  F.  Duffield  was  a  well- 
digested,  carefully  written  essay. 

Starting  with  the  German  motto  from  Lessing,  IVer 
viel  weiss  hat  viel  zu  sorgin  ("  He  who  knows  much  has 
much  to  care  for  "),  he  claimed  that  Lord  Bacon  uttered  a 
truth  when  he  said, ''  The  greatest  trust  between  man  and 
man  was  the  trust  of  giving  counsel,"  and  if,  said  the 
essayist,  he  were  in  our  profession  and  called  to  the  wit- 
ness-stand, in  Wayne  County  especially,  he  would  have 
probably  added,  "and  no  counsellors  are  so  poorly 
paid."  This  province  of  giving  counsel  cannot  be  re- 
served by  the  legal  fraternity  alone,  they  are  not  the  only 
Gamaliels  at  whose  feet  the  young  Sauls  of  Tarsus  must 
learn  wisdom.  A  lawyer  can  craniy  but  he  cannot  counsel 
on  our  specialties.  Physicians  as  counsellors  in  their 
departments  of  knowledge  are  denominated  "experts." 
So  far  they  seem  to  have  been  expert  in  telling  all  they 
know  and  not  expert  at  getting  paid  for  it. 

He  described  the  ancient  law,  which  was  intended  to 
prevent  the  perfidy  of  advocates,  and  showed  how  during 
the  time  of  Claudius  it  was  so  modified  that  advocates, 
were  permitted  to  receive  any  sum  up  to  10,000  sesterces, 
or  about  $400,  and  thus  was  paved  the  way  for  that 
amendment  under  Claudius  which  recognized  the  fact 
that  professional  services  have  created  something  more 


than  imperfect  obligation  on  the  part  of  the  recipient,  and 
entitled  the  practitioner  to  his  '*  quiddara  honorarium," 
even  through  the  intervention  of  the  magistrate.  Such 
was  the  high  standard  affixed  to  the  exercise  of  a  liberal 
profession  among  the  most  polished  people  of  antiquity. 
The  author  of  the  paper  gave  two'  sets  of  cases,  viz. : 
I,  cases  favoring  extra  compensation ;  2,  cases  denying 
the  right  to  extra  compensation — reference  being  had  to 
Buchman  vs.  State  of  Indiana,  59  Ind.,  i ;  U.  S.  vs, 
Howe,  12  Central  Law  Journal,  193;  and  for  American 
cases  denying  the  right  of  compensation  reference  was 
had  to  53  Alabama,  389,  before  the  Supreme  Court  of 
Alabama,  ex  parte  Dement 

Dr.  D.  also  reviewed  the  article  by  Rasselle  John- 
son which  appears  in  the  June  number  of  the  North 
American  Review^  showing  his  fallacious  definition  of 
the  word  witness  in  that  article,  is  not  consistent,  "for 
the  expert  is  not  testifying  of  facts,**  but  is  acring  as  an 
interpreter  by  making  legible  that  which  was  written  in 
blood,  or  paint,  or  other  stain  upon  the  clothing.  He 
stands  as  Daniel  at  Belshazzar's  feast,  interpreting  the 
mysterious,  and  to  the  mass  the  unknown  characters  which 
shine  out  in  the  testimony,  but  which  cannot  be  inter- 
preted by  the  jury.  Called  by  opposing  counsel  rather 
than  by  the  judge,  answering  alternately  yes  or  no  to  con- 
tradictory hypothetical  questions  ingeniously  based  on 
selected  facts  in  testimony,  and  so  with  show  of  science, 
falsely  so  called,  leaving  the  jury  more  befogged  than 
ever.  True  science  asks  a  different  definition  from  this, 
and  indignantly  appeals  from  such  data. 

It  can  never  be  reached  without  distinct  and  honest 
co-operation  between  legal  and  medical  experts.  The 
bar  must  reach  forth  an  honest  hand  to  the  physician  and 
he  must  conscientiously  respond ;  both  must  be  willing 
searchers  for  that  gem  which  is  the  crystallization  of 
years  of  medical  experience  and  science  realizing  the 
truth  of  Goethe's  words,  Die  weisheit  ist  nur  in  der  war- 
heit  (**  Wisdom  is  only  in  truth"). 

President  Dr.  A.  F.  Whelan,  of  Hillsdale,  called 
Vice-President  H.  Tupper  to  the  chair,  and  read  his 

ANNUAL  ADDRESS. 

He  reviewed  the  history  and  progress  8f  medicine,  and 
said  it  had  done  more  to  break  up  dark  faiths  by  build- 
ing up  the  minds  of  the  people,  and  despite  the  opposi- 
tion and  hindrances  that  have  always  been  in  the  way  it 
will  be  triumphant.  He  closed  with  an  appropriate 
tribute  to  the  memory  of  Drs.  Jas.  H.  Jerome  and  Wm. 
Brownell,  deceased. 

Dr.  T.  a.  McGraw,  of  Detroit,  read  a  paper  of  great 
practical  value  on 

DIAGNOSIS   OF  TUMORS. 

He  thought  that  all  abnormal  growths  were  the  result  of 
irritation  or  a  slow  inflammatory  process.  Hypertrophy 
was  the  result  of  increased  nutritive  action  and  is  not  a 
neoplasm.  He  discussed  quite  extensively  the  nature 
and  pathology  of  tumors.  He  had  made  a  thorough 
study  of  cystic  tumors  of  the  breast,  and  thought  that 
they  should  be  removed  entirely  as  soon  as  discovered, 
and  if  they  showed  a  tendency  to  return  the  entire  breast 
should  be  removed.  He  thought  that  all  tumors  had 
better  be  taken  out  promptly  and  thoroughly.  He  had 
often  known  apparently  innocent  growths  to  take  on  a 
malignant  action  from  local  irritation.  He  believed  that 
warts  and  moles  were  often  irritated  until  they  became 
malignant.  He  thought  that  the  better  way  to  remove  a 
tumor  was  to  use  the  knife. 

Dr.  a.  B.  Palmer,  of  the  State  University,  read  a 
paper  on 

PROSTATIC  HYPERTROPHY  AND  URINARY  OBSTRUCTION, 
ITS   TREATMENT   WITHOUT  CATHETERISM, 

which,  from  the  simplicity  and  to  many  the  novelty  of 
the  method,  attracted  particular  attention. 

After  referring  to  the  frequency  of  prostatic    enlarge- 
ment in  advanced  life  and  to  the  occurrence  of  what 


THE  MEDICAL  RECORD. 


23 


Spiemlart  calls  the  **  catheter  period,"  which  means  a 
period  of  such  obstruction  to  the  passage  of  the  urine  in 
which  the  bladder  is  not  completely  emptied,  an  irrita- 
tion of  the  urinary  organs  of  a  somewhat  decided  char- 
acter occurs,  and  which  also  implies  that  from  that  time 
DDtrard  the  catheter  must  be  a  constant  companion 
and  one  likely  to  be  brought  into  frequent  use  ;  and  after 
fbrther  referring  to  the  great  unpleasantness  and  not  in- 
frequent dangers  of  its  introduction  —  the  "catheter 
fever"  and  the  still  more  frequent  shock — the  method 
of  procedure  in  the  management  of  cases  was  described 
as  follows :  "  The  urethra  is  to  be  filled  with  urine  as  in 
an  effort  at  micturition.  The  penis  is  then  grasped  by 
the  hand  of  the  patient  and  the  urethra  is  pressed  upon 
near  the  glands  or  in  some  part  of  its  course  sufficient  to 
introduce  the  flow ;  and  then  by  straining,  as  in  an  at- 
tempt to  forcibly  empty  the  bladder,  the  distention  of  the 
urethra  is  produced.  This  distending  pressure  is  gentle, 
steady,  diffused,  and  painless,  and  may  be  applied  and  sus- 
tained at  will,  and  in  a  majority  of  cases,  if  daily  repeated 
for  a  time  and  afterward  occasionally,  and  if  it  is  done 
thoroughly,  and  especially  if  commenced  at  an  early 
period  o(  the  obstruction,  it  will  overcome  this  form  of 
stricture  eflfectually  and  without  irritation  or  danger." 

A  case  as  a  specimen  of  many  others  was  given  in 
detail  as  illustrating  the  efficacy  of  the  measure. 

The  paper  concluded  with  the  statement  that  from 
sufficient  experience  the  efficacy  and  value  of  this  method 
had  been  demonstrated  and  it  was  strongly  commended 
to  the  attention  of  the  profession. 

In  compliance  with  a  resolution  previously  made  by 
Dr.  Pratt  and  adopted  by  the  Society,*  the  President  ap- 
pointed a  committee  to  nominate  officers  for  the  ensuing 
year,  except  President.  The  committee  was  composed 
of  Drs.  William  Brodie,  H.  McColl,  S.  H.  Clizbee,  G. 
L  Johnson,  and  £.  P.  Christian. 

Dr.  G.  K.  Johnson's  paper  was  on  motion,  made  the 
special  order  for  9  a.m.  next  day. 

Dr.  K  L.  Shurly  as  one  of  a  committee  appointed 
by  the  U.  S.  Climatological  Association  to  collect  data  of 

KATURAL  CAUSES   PREDISPOSING  TO  PHTHISIS   PUL- 
MONALIS, 

appealed  to  the  members  present  and  the  profession 
throoghout  the  State  to  assist  him  by  reporting  to  him 
ofi  blank  cards  which  he  distributed  to  those  present. 
As  adjournment  would  take  place  before  all  the  papers 
offered  could  be  read,  on  motion  of  Dr.  Ward,  authors 
of  papers  were  allowed  to  read  them  by  title,  and  when 
so  read  they  were  referred  to  the  Publication  Committee. 

STERIUTY   IN  WOMEN. 

Dk.  J.  H.  Carstens,  of  Detroit,  read  a  paper  on 
^Sterility  in  Women,"  calling  attention  to  the  frequency  of 
ds&ease  and  the  great  importance  of  this  condition  to 
the  State,  and  especially  to  the  individual  so  afflicted. 
Tbatin  order  to  understand  the  cause  and  cure  of  ster- 
ility it  was  best  to  consider  the  essentials  of  pregnancy. 
Then  we  come  to  the  conclusion,  that  sterility  can  be 
cored  by  absence  of  disease  of  ovaries,  Fallopian  tubes, 
^placements  of  uterus,  strictures  and  occlusions  of 
Bterine  canal  or  of  the  vagina.  These  were  the  causes 
in  women,  but  the  husband  was  sometimes  to  blame  and 
sboald  never  be  neglected.  Especially  should  we  be 
parded  in  our  prognosis  and  not  promise  a  cure,  as  we 
aever  could  be  positive  that  pregnancy  would  occur,  even 
iftcr  the  cure  of  the  diseases  which  often  cause  sterility. 


Second  Day — Morning  Session. 

Meeting  called  to  order  by  the  President  Calling  of 
the  roll  and  reading  of  the  minutes  was  dispensed  with. 

Dr.  Brearey,  as  chairman  of  the  Committee  on  Ne- 
crology, rendered  a  verbal  report,  and  asked  further  time 
to  complete  his  written  report  and  refer  the  same  to  the 
Committee  on  Publication.     Granted. 


Report'  of  a  case  of 

PERINEPHRITIC   ABSCESS, 

with  remarks,  by  Dr.  George  K.  Johnson,  of  Grand 
Rapids,  was  next  called  for  and  read  This  was  a  case 
occurring  in  a  man  twenty-two  years  of  age,  whose  ill- 
ness was  marked  by  symptoms  seen  in  typhoid  fever, 
which  symptoms  partially  abated.  Soon,  however,  an 
indefinite  ailment,  characterized  by  weakness,  want  of 
appetite,  loss  of  flesh,  feeble  pulse,  cachectic  fever,  and 
pain  in  left  iliac  and  lumbar  region,  led  him  to  again 
consult  the  doctor.  In  a  word  there  was  present  the 
group  of  phenomena  which  signalized  hectic  or  pyoge- 
nesis.  Pain  in  the  left  costo-iliac  space  had  come  on 
and  was  increased  by  pressure.  A  feeling  of  weight  in 
left  flank  and  left  upper  abdomen  was  complained  of,  but 
no  pain  in  genital  tract  or  groin.  Urine  voided  fre- 
quently, loaded  with  pus,  but  without  blood,  mucus,  or 
casts.  Left  half  of  abdomen  distended  with  fluctuating 
tumor,  easily  traced.  Hypodermic  needle  passed  into 
the  tumor  withdrew  a  drachm  of  pus  and  confirmed  the 
diagnosis.  The  body  forces  fast  waning  and  danger  that 
the  cyst  would  rupture  and  pour  its  contents  into  the  cavity 
of  the  abdomen,  the  doctor  decided  to  at  once  aspirate  the 
tumor.  Passing  the  needle  at  the  external  margin  of  left 
rectus,  two  inches  below  the  level  of  the  umbilicus,  he 
removed  eighty-four  ounces  of  pus.  Within  a  few  hours 
rehef  came,  fever  left,  and  pain  vanished.  On  the  second 
day  the  temperature  of  the  patient  reached  100^  F.  in 
the  morning  and  104°  F.  in  the  evening,  and  on  the 
fourth  day  the  temperature  was  99^°  F.  in  the  morning, 
and  104^°  F.  in  the  evening,  when  it  reached  its  climax, 
the  patient  having,  though  restless,  suffered  no  pain  or 
swelling  of  the  parts  since  aspiration.  Six  days  after  the 
aspiration  some  fulness  appeared  over  the  site  of  the  tu- 
mor, and  after  a  few  days  there  was  found  to  be  consid- 
erable reaccumulation  of  pus.  But  the  discharge  by  the 
urinary  conduits  was  so  free  that  no  further  accumulation 
took  place  and  all  tumefaction  slowly  but  steadily  disap- 
peared. Three  months  after  aspiration  the  patient  seemed 
entirely  well,  appetite,  strength,  flesh,  and  spirits  were  fully 
restored.  The  urine  was  normal,  and  all  traces  of  the 
tumor  was  gone. 

The  author  closed  his  paper  by  a  somewhat  compre- 
hensive and  very  instructive  review  of  the  somewhat 
meagre  literature  of  the  class  of  cases  to  which  the  one 
reported  was  typical,  gave  a  careful  history  of  the  path- 
ology and  course  of  the  disease,  calling  attention  to 
important  points  in  its  diagnosis,  so  essential  to  the  prac- 
titioner, who  is  often  befogged  for  want  of  proper  descrip- 
tion by  authors  of  the  symptoms  and  signs  of  probable 
and  possible  value  in  localizing  ancl  diagnosing  peri- 
nephritis and  perinephritic  abscess. 

Dr.  E.  p.  Christian  read  a  paper  on  "Placenta 
Previa,**  which  was  referred  to  the  Publication  Committee. 

officers  for  the  ensuing  year. 

The  Committee  on  Nominations  rendered  their  report 
recommending  officers  for  the  ensuing  'year  as  follows  : 
Vice-Presidents — J.  Perkins,  Owasso;  J.  M.  Cook, 
Muskegon  ;  Gordon  Chittock,  Jackson ;  Case  Brumme, 
Detroit ;  Secretary — Geo.  E.  Ranney,  Lansing  ;  Treas^ 
urer — A.  R.  Smart,  Hudson  ;  Judicial  Council — F.  K. 
Owen,  Ypsilanti  j  C.  V.  Tyler,  Bay  City ;  H.  M.  Clou, 
Lapeer  ;  Delegates  to  American  Medical  Association — 
Wm.  Brodie,  Detroit;  H.  B.  Baker,  Lansing;  J.  H. 
Bennett,  Coldwater;  J.  B.  Book,  Detroit;  W.  F. 
Breakey,  Ann  Arbor ;  C.  Brumme,  Detroit ;  J.  H.  Car- 
sten,  Detroit ;  S.  H.  Clizbee,  Coldwater ;  L.  Connor, 
Detroit;  E.  S.  Dunstan,  Ann  Arbor;  S.  P.  Duffield, 
Dearborn  ;  S.  S.  French,  Battle  Creek  ;  A.  D.  Hoga- 
dorne,  Lansing;  H.  O.  Hitchcock, *  Kalamazoo ;  ,G. 
K.  Johnson,  Grand  Rapids ;  D.  Maclean,  Deti'oit ;  H. 
M.  Cole,  Lapeer ;  F.  M.  Oakley,  Ypsilanti ;  F.  K. 
Owen,  Ypsilanti ;  A.  B.  Palmer,  Ann  Arbor ;  F.  Pratt, 
Kalamazoo ;   G.   E.  Ranney,  Lansing ;   W.   F.  Sigler, 


24 


THE  MEDICAL  RECORD. 


[July  5. 1884. 


Pinkney  ;  H.  A.  Shank,  Lansing  ;  E.  Snow,  Dearborn ; 
C.  F.  Southworth,  Monroe ;  T.  H.  Tuppcr,  Bay  City ; 
C.  V.  Tyler,  Bay  City  ;  D.  C.  Wade,  Holly ;  A.  F. 
Whelan,  Hillsdale ;  Chas.  Shepard,  Grand  Rapids. 

The  report  of  the  committee  was  adopted. 

The  Society  next  proceeded  to  ballot  for  President, 
with  the  following  result :  Whole  number  of  votes  cast 
196,  of  which  Donald  Maclean  received  126;  S.  S. 
French,  6^  ;  scattering,  6. 

Dr.  Maclean  was  thereupon  declared  elected. 

The  usual  votes  of  thanks  for  the  many  courtesies  ex- 
tended by  the  physicians  and  citizens  of  Grand  Rapids 
and  to  the  retiring  officers  were  then  passed. 

Dr.  Miles,  of  Port  Huron,  extended  an  invitation 
to  the  Society  to  hold  its  next  annual  meeting  at  Port 
Huron.    Carried. 

Dr.  a.  W.  Nichols,  of  Greenville,  read  an  interesting, 
practical,  instructive  paper  on  •*  Nasal  Catarrh,"  which 
was  referred  to  Committee  on  Publication. 

GRANULATED    LIDS. 

Dr.  Eugene  Smith,  of  Detroit,  read  a  paper  on  "  Gran- 
ulated Lids  "  and  related  a  case  in  which  he  had  used 
jeqtiirity  with  good  effect.  He  uses  a  three  per  cent 
solution,  and  applies  it  two  or  three  times  a  day  for 
three  or  four  days,  and  then  follows  with  boracic  acid. 
He  thinks  this  remedy  is  well  adapted  to  old  chronic  cases 
where  there  is  no  purulent  secretion. 

MISCELLANEOUS    BUSINESS. 

A  paper  by  Dr.  R.  J.  Kirkland  on  "  Chronic  Catar- 
rhal Otitis,"  one  by  Dr.  A.  R.  Smart  on  "  Therapeu- 
tics  of  Dysmenorrhoea,"  one  by  Dr.  D.  W.  C.  Wade  on 
**  Uterine  Displacements,"  were  all  interesting,  able  pa- 
pers,  and  were  referred  to  the  Committee  on  Publication. 

Over  two  hundred  physicians  were  in  attendance,  up- 
ward of  eighty  of  whom  were  elected  members  at  this 
meeting. 

The  Society  transacted  considerable  miscellaneous 
business  pertaining  to  local  and  personal  matters,  and 
adjourned  till  the  second  Wednesday  of  June,  1885. 


G^oweepon&j^nct. 


OUR   LONDON    LEITER 

(From  our  Special  Correspondent. } 

CONFERENCES  ON  HEALTH  —  DOMESTIC  SANITARY  AR- 
RANGEMENTS OF  THE  METROPOLITAN  POOR — DOMES- 
TIC SANITATION  OF  RURAL  DISTRICTS — INDUSTRIAL 
DISEASES — INFECTIOUS  DISEASES — DISPOSAL  OF  THE 
DEAD. 

London,  June  Z4«  1884. 

What  may  be  termed  the  Health  Congress  began  on 
Monday  last,  June  9th.  This  consists  of  a  series  of  con- 
ferences organized  by  a  joint-committee  of  the  following 
bodies  :  Society  of  Medical  Officers  of  Health,  Sanitary 
Institute  of  Great  Britain,  Parkes  Museum  of  Hy- 
giene. 

The  meetings  have  been  thrown  open  to  all  visitors  to 
the  Health  Exhibition.  No  one  will  be  sanguine  enough 
to  believe  that  a  tithe  of  the  sightseers  who  visit  the  Ex- 
hibition will  find  their  way  into  the  conference  room, 
and  patiently  listen  to  the  reading  of  the  papers  ;  but  the 
chief  end  and  aim  of  the  meetings  will  be  gained  if, 
through  the  publicity  given  to  them,  the  public  gets  a 
more  intimate  acquaintance  with,  and  places  a  deeper 
trust  in,  the  science  and  practice  of  hygiene.  Many  of 
the  subjects  discussed,  and  propositions  brought  forward, 
have  long  been  familiar  to  sanitarians,  but  to  ordinary 
medical  practitioners,  who  are  so  largely  occupied  in  the 


treatment  of  disease,  they  are  probably  less  well-known. 
In  any  case  the  threshing  out  again  of  health  topics  can- 
not fail  to  be  beneficial. 

The  ball  was  opened  on  Monday  by  the  reading  of  a 
paper  on  "  Domestic  Sanitary  Arrangements  of  thi 
Metropolitan  Poor,"  by  Dr.  Tripe.  Dr.  Tripe  is  a  well- 
known  sanitarian,  and  as  the  medical  officer  of  health 
to  a  populous  parish  in  the  East  end  of  London,  is  well 
qualified  to  speak  on  the  subject  from  actual  observa- 
tion. He  remarked  that  the  chief  defects  arose  from 
want  of  a  proper  water-supply.  This,  of  course,  led  to 
defective  drainage  and  escape  of  sewer-gas  from  un- 
flushed  drains  and  dried-up  traps.  Unemptied  dust-bins 
were  also  great  nuisances. 

Mr.  Ernest  Turner,  who  is  an  architect,  and  conse- 
quently approached  the  subject  from  an  architectural 
standpoint,  followed  with  a  paper  on  "  The  Improvement 
of  the  Sanitary  Arrangements  of  Metropolitan  Houses." 
It  is  satisfactory  to  find  that  a  few  architects  are  begin- 
ning the  study  of  hygiene.  A  whole  number  of  The 
Medical  Record  could  easily  be  filled  with  accounts 
of  unsanitary  arrangements  perpetrated  by  architects  in 
the  past.  I  could  testify  to  a  good  many  from  personal 
observation.  It  is  not  all  the  fault  of  the  "jerry-build- 
ers." A  West  end  mansion  I  frequently  pass  had  the 
soil-pipe  imbedded  in  the  wall  of  the  dining-room,  and 
constructed  of  such  thin  lead  that  it  gave  way  and  caused 
a  leakage  of  sewage  through  the  wall,  which  continued 
for  some  time.  When  the  cause  was  at  last  discovered, 
the  owner  determined  to  do,  what  in  fact  should  have 
been  done  at  first,  viz.,  place  all  the  drain-pipes  outside 
the  building. 

On  Tuesday  the  conference  was  continued  by  the 
reading  of  a  paper  by  Dr.  George  Wilson  on  "  Domestic 
Sanitation  of  Rural  Districts."  Dr.  Wilson  quoted  the 
report  of  the  agricultural  commission  of  1867,  which 
showed  that  one-third  of  the  rural  homes  of  England  were 
unfit  to  be  used  as  dwellings,  and  that  therefore  700,000 
hovels  ought  to  be  pulled  down.  In  many  villages  he 
knew  himself  half  the  cottages  contained  only  two  sleep- 
ing-rooms, and  about  ten  per  cent  only  one,  and  his  dis- 
trict (Warwickshire)  was  considered  by  the  commission 
better  than  many.  He  said  the  poverty  of  the  owners 
and  the  low  wages  earned  by  the  occupiers  were  obstacles 
to  improvement.  Dr.  Wilson  advocated  for  rural  dis- 
tricts the  adoption  of  the  **  pail  system "  or  else  ash-pit 
closets. 

Mr.  Boulnois,  civil  engineer,  then  read  a  paper  on 
"Sanitary  Houses  for  the  Working  Classes  in  Urban 
Districts."  He  condemned  the  erection  of  huge  blocks, 
also  basement  rooms.  Flat  roofs  were  good  for  gardens 
or  drying  grounds,  also  for  escape  in  case  of  fire.  He 
urged  the  advantages  of  a  constant  water-supply. 

On  Wednesday,  a  paper  on  "  Industrial  Diseases  "  wai 
read  by  Dr.  Bristowe,  F.RS.,  Physician  to  St  Thomas' 
Hospital,  and  Medical  Officer  of  Health  for  CamberwelU 
The  causation  and  prevention  of  industrial  diseases  is 
subject  to  which  sanitarians  have  devoted  a  good  deal 
attention  of  late  years,  and  Dr.  Bristowe  made  the  moi 
of  his  subject  in  the  limited  time  allotted  him,  dwelling  ii 
succession  on  the  chief  diseases  caused  or  aggravated  b; 
different  trades,  and  the  modes  of  prevention  that  may  U 
adopted. 

On  Thursday  an  interesting  paper  was  read  by  Dr 
Thursfield  on  "  The  Spread  of  Infectious  Diseases  ihroug 
the  agency  of  Milk."  Dr.  Thursfield  remarked  on  iU 
great  increase  in  the  consumption  of  cow's  milk  both  bj 
adults  and  infants — in  the  latter  case,  through  the  unfoi 
tunate  increase  in  the  number  of  women  physically  i 
competent  for  lactation.  It  was  presumable  that  in  mai 
cases  of  disease  from  milk,  the  source  had  not  beei 
suspected,  but  making  allowance  for  doubtful  cases, 
thought  it  might  be  accepted  as  a  fact  that  enteric  ani 
scarlet  fevers  had  been  repeatedly  disseminated  by  mill 
and  there  was  also  very  strong  evidence  as  to  the  spre: 
of  diphtheria  through  the  same  agency.     He  consider 


July  5,  1884.] 


THE   MEDICAL  RECORD. 


25 


that  the  boiling  of  milk  practically  conferred  immunity 
from  infection.  Dr.  Thursfield  enumerated  the  restric- 
tions it  was  desirable  to  place  on  the  sale  of  milk,  and 
observed  that  an  urban  sanitary  authority  should  have 
the  power  to  stop  the  sale  of  milk  sent  from  any  particular 
fami,  pending  investigations,  but  that  there  should  be 
liability  for  compensation  if  the  step  proved  unnecessary. 
In  the  discussion  which  followed  the  reading  of  the  paper, 
Dr.  De  Chaumont,  professor  of  hygiene  at  Netley,  as- 
sented to  the  views  expressed  as  to  the  frequent  convey- 
iDce  of  infectious  diseases  by  milk,  but  stated  that  the 
views  received  here  did  not  find  acceptance  abroad,  and 
that  some  of  his  French  and  German  friends  looked  on 
the  whole  thing  as  a  gigantic  joke.  Dr.  Corfield  read  a 
paper  on  "  The  Spread  of  Infectious  Diseases  through 
other  Agencies  than  Milk.'* 

On  Friday  the  "  Notification  of  Infectious  Diseases  " 
was  discussed  in  two  papers  by  Drs.  Alfred  Hill  and  Al- 
fred Carpenter,  respectively.     Dr.  Hill  urged  its  impor- 
tance as  the  only  means  by  which  news  of  an  epidemic 
could  be  obtained,  and  was  of  opinion  that  it  should  be 
compulsory  on  all  medical  men  to  notify.     Dr.  Carpen- 
ter considered  notification  a  moral  duty  to  the  State, 
and  that  it  was  the  duty  of  the  State  to  enforce  it.     The 
duurman,  Earl  Fortescue,  spoke  of  the  danger  of  in- 
fcrfering  with  cither  personal  liberty  or  the   rights  of 
property,  and  in  summing  up  the  discussion  which  fol- 
lowed the  reading  of  the  papers,  as  on  previous  days, 
said  he  thought  a  case  had  been  made  out  for  notifica- 
tion, but  it  appeared  to  him  that  the  duty  should  be  laid 
on  the  householder  rather  than  on  the  doctor.    With  this 
opinion  the  bulk  of  the  profession  will  concur.     It  is 
mainly  the  professed  sanitarians  who  wish  to  compel  the 
doctor  to  notify.     Ordinary  practitioners  are  against  it. 
It  would  no  doubt  be  a  great  lightening  of  the  labors  of 
medical  officers  of  health,  but  at  the  expense  of  an  in- 
crease of  worry  and  responsibility  to  the  actual  practi- 
tioners.    It  is  significant  that  out  of  about  120  medical 
men  at  Brighton,  100  have  petitioned  against  notification 
being  made  compulsory  in  that  town. 

The  subject  for  to-day  is  the  "  Disposal  of  the  Dead,*' 
OQ  which  Mr.  Wynter  Blyth,  medical  officer  of  health 
for  Marylebone,  will  read  a  paper.  Mr.  Eassie  will  fol- 
lov  with  one  on  *^  Cremation,"  of  which  he  is  an  advo- 
cate. 


SUCCESSFUL  LOCAL  APPLICATION  OF  ETHER 
TO  MUCOUS  MEMBRANE  OF  BLADDER  FOR 
NEURALGIA  OF  THAT  ORGAN. 

To  THX  EsiTOft  OP  The  licotou.  Rboobd. 

Sol  :  Apropos  of  etherization  by  the  rectum,  permit  me 
to  mention  another  channel  through  which  I  have  in- 
trodnced  ether  into  the  economy.  In  two  cases  of  severe 
and  obstinate  neuralgia  of  the  bladder,  which  had  re- 
si^ed  morphine,  belladonna,  hyoscyamus,  fomentations, 
ia  hct,  almost  everything  recommended  in  the  treatment 

[o^d!i^  distressing  affection,  I  injected  into  the  bladder 
ctber,  gtt.  X.,  in  water,  3  ij.  Any  detailed  account  of  the 
cases  your  valuable  time  and  space  will  not  permit  and, 
<bcrefore,  I  can  only  add  that  within  one  minute  the  ether 
was  perceptible  in  the  breath  in  both  instances,  and  with- 
in five  minutes'  time  there  was  perfect  relief  from  pain 
viuch  had  been  previously  most  severe.  The  conclusions 
were  verified  a  number  of  times. 

The  mucous  coat  of  the  bladder  being  non-absorbing, 
8  some  authorities  claim,  how  could  the  ether  pass  so 
qeickly  into  the  circulation  ?  Has  ether  ever  been  used 
in  this  manner  before  and  what  have  been  the  results. 
I  have  been  unable  to  find  a  precedent  for  its  use  in  the 
iterature  upon  the  subject. 

Very  respectfully, 


19B  Sbobgia  Stibbt,  Bvftalo. 


John  Parmenter,  M.D. 


Official  List  €f  Changes  in  the  Stations  and  DtUiss  ef  Officers 
serving  in  the  Medical  Department^  United  States  Army^ 
from  June  22  to  June  28,  1884. 

Clements,  Bennett  A.,  Major  and  Surgeon.  Ordered 
to  relieve  Major  Jos.  P.  Wright,  Surgeon,  of  his  duties 
as  Attending  Surgeon  at  the  Leavenworth  Military  Prison, 
Fort  Leavenworth,  Kansas.  Major  Wright,  on  being 
relieved,  ordered  to  report  to  the  Commanding  General 
Department  of  Texas,  for  assignment  to  duty.  S.  O. 
144,  par.  7,  A.  G.  O.,  June  21,  1884. 

Dickson,  John  M.,  Captain  and  Assistant  Surgeon, 
assigned  to  duty  as  Post  Surgeon,  Alcatraz  Island,  Cali- 
fornia. S.  O.  71,  par.  3,  Headquarters  Department  of 
California,  June  19,  1884. 

GiRARD,  A.  C,  Captain  and  Assistant  Surgeon.  Grant- 
ed leave  of  absence  for  six  months,  with  permission  to  go 
beyond  sea,  S.  O.  148,  par.  11,  A.  G.  O.,  June  26, 
1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy,  during  the  week  ending  June  28,  1884. 

Knight,  J.  S.,  Surgeon.     Placed  on  Retired  List 

Whiting,  R.,  Passed  Assistant  Surgeon.  Detached 
from  U.  S.  S.  Vermont,  and  ordered  to  Marine  Rendez- 
vous, New  York. 

Babin,  H.  J.,  Surgeon.  Detached  from  Marine  Ren- 
dezvous, New  York,  and  ordered  to  U.  S.  S.  Minnesota. 

Wells,  H.  M.,  Surgeon.  Ordered  for  examination 
preliminary  to  promotion. 

LuMSDEN,  G.  P.,  Passed  Assistant  Surgeon.  De- 
tached from  U.  S.  S.  Pensacola  and  placed  on  waiting 
orders.' 

ptMicaX  Items* 

Contagious  Diseases — ^Weekly  Statement. — Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  June  28,  18S4 : 


Week  Ending 


June  21, 1884.. 
June  28,  1884. . 

June  21, 1884.. 
June  28,  1884.. 


I 


130 
186 


I 


The  Validity  of  a  Life  Insurance  Policy. — An 
important  insurance  decision  has  recently  been  rendered 
in  the  United  States  Supreme  Court,  sustaining  the 
validity  of  a  policy  although  statements  were  made  by 
the  insured  which  were  not  absolutely  true.  He  was 
asked  among  other  questions  whether  he  ever  had  had 
asthma,  scrofula,  or  consumption,  and  he  answered  no. 
After  his  death  it  was  found  that  he  had  one  of  these  dis- 
eases in  an  incipient  form  at  the  time  of  making  this 
answer,  but  was  unaware  of  it  himself.  This  condition 
of  the  case  was  held  to  avoid  the  policy  by  the  trial  court 
and  an  appeal  was  taken  from  the  decision  to  the  Supreme 
Court,  where  it  has  just  now  been  reversed.  The  latter 
court  stated  that  if  the  insured  had  no  reason  to  believe 
that  he  was  afflicted  with  the  disease  at  the  time  of  mak- 
ing the  apphcation,  he  should  not  be  precluded  from  the 
advantages  of  the  policy. 


26 


THE  MEDICAL  RECORD. 


[July  5,  1884. 


AcxiNOMYCOSis, — At  the  last  meeting  of  the  London 
Pathological  Society,  Mr.  Frederick  Treves  gave  a  further 
account  of  his  supposed  case  of  actinomycosis.  The  dis- 
ease began  two  years  ago  after  erysipelas.  It  commenced 
with  a  swelling  over  the  lower  jaw,  on  the  left  side,  which 
increased  and  was  excised.  The  wound  would  not  heal 
and  an  ulcer  remained.  The  glands  at  the  back  of  the  neck 
then  enlarged,  and  nodules  appeared  over  the  chest,  about 
thirty  in  all.  As  each  nodule  appeared  under  the  skin 
it  developed  a  pustule  ;  ulceration  and  fungation  fol- 
lowed. Mr.  Treves  said  that  although  no  fungi  were 
found,  and  no  communication  with  animals  traceable,  he 
was  inclined  to  call  it  actinomycosis,  as  Ponfick's  de- 
scription was  so  accurately  realized.  Mr.  Treves  re- 
moved several  of  the  nodules  and  the  patient  seemed  to 
do  well,  but  a  second  operation  was  succeeded  by  great 
weakness  and  the  patient  died  in  a  month.  Secondary 
deposits,  in  the  form  of  round  yellowish  nodules,  were 
found  in  the  lung,  liver,  spleen,  and  kidney.  Mr.  Watson 
Cheyne  had  examined  the  organs,  but  had  been  unable  to 
discover  any  micro-organisms  or  cultivate  any  micro- 
parasites.  The  structure  resembled  alveolar  sarcoma. 
Clusters  of  cells  were  arranged  in  a  plexiform  manner 
with  some  connective  tissue.  Mr.  Treves  remarked  that 
the  suppuration  of  each  nodule,  soon  after  its  appearance, 
was  remarkable,  and  so  was  the  protracted  character  of 
the  malady.  He  considered  that  the  diagnosis  at  times 
lay  between  scrofula,  cancer,  farcy,  and  actinomycosis. 

Mr.  Hulke,  who  had  seen  the  patient  during  life, 
thought  the  case  resembled  farcy. 

Mr.  Watson  Cheyne  remarked  that  as  the  farcy  organ- 
ism could  be  easily  cultivated,  and  cultivation  experi- 
ments had  produced  negative  results,  farcy  might  be  ex- 
cluded.    He  thought  the  case  was  one  of  carcinoma. 

Mr.  Treves  remarked  that  the  case  was  slower  than  one 
of  farcy. 

Contagious  Diseases  Acts. — The  total  repeal  of 
the  Contagious  Diseases  Acts  is  likely  to  be  soon  ac- 
complished. Since  the  adverse  vote  of  the  House  of 
Commons  last  year  the  action  of  the  compulsory  clauses 
has  been  suspended,  and  the  Secretary  for  War  now 
proposes  to  bring  in  a  bill  for  the  abolition  of  the  re- 
maining provisions  of  the  acts.  There  is  good  evidence 
that  venereal  affections  have  increased  during  the  last 
year,  and  should  the  new  bill  pass,  a  further  increase 
may  be  expected.  Public  opinion,  though,  will  not  sup- 
port the  acts,  and  the  accounts  of  how  the  French  system 
works  have  done  a  great  deal  to  disgust  every  one  with 
all  systems  of  compulsion. 

Report  of  a  Case  of  Multiple  Pi^egnancy  ;  CiSSAR- 
EAN  Section. — The  following  interesting  case  was  read 
before  the  Montgomery  County,  O.,  Medical  Society  by 
Dr.  C.  H.  Humphreys,  of  Dayton,  O.,  and  created  quite  a 
sensation :  "The  rarity  of  Caesarean  section  always  lends 
interest  to  every  new  case.  I  was  recently  the  accouch- 
eur on  an  occasion  requiring  its  performance,  and  beg 
leave,  therefore,  briefly  to  report  it.  On  a  Sunday  even- 
ing, some  three  weeks  ago,  a  gendeman  entered  my  of- 
flce,  and  with  some  hesitation  requested  my  attendance 
upon  the  subject  of  this  sketch  in  confinement,  who  was 
a  rather^handsome  young  primipara,  unmarried,  a  native 
of  Massachusetts,  and  since  last  summer  a  resident  of 
this  city.  Labor  began  the  night  previous,  and  about  9 
A.M.  a  living  fcetus  was  bom  without  assistance.  The 
pains  continued  unabated,  however,  and  toward  evening 
it  was  decided  medical  aid  should  be  called.  Upon  arri- 
val I  made  a  vaginal  examination  and  diagnosed  multiple 
pregnancy.  As  well  as  I  could  determine,  the  dystocia 
was  caused  by  a  transverse  presentation.  The  patient 
showedj  much  exhaustion  and  was  constantly  changing 
her  position  in  bed.  Version  by  external  manipulation 
was  fairly  tried,  but  this  procedure  proved  an  entire  fail- 
ure. I  did  not  think  introduction  of  my  hand  within  the 
uterus  to  perform  version  possible,  and  did  not  attempt 
it.     Her  condition  contra-indicated  such  violence.     At 


about  6  P.M.,  the  patient's  condition  being  unpromising, 
and  it  being  evident  that  something  must  be  done  without 
delay,  I  determined  in  my  dilemma  to  make  at  once 
Caesarean  section.  Accordingly  preparation  was  hastily 
made,  and  the  patient  placed  on  an  operating  table.  She 
at  first  declined  an  anaesthetic,  but  Anally  consented  to 
the  use  of  ether,  which  acted  well.  Commencing  near 
the  umbilicus,  I  made  an  incision  about  three  inches 
long  in  the  median  line  and  opened  the  abdominal 
cavity.  The  uterus  presenting,  it  was  incised  to  corres- 
pond. A  dead  foetus  with  membranes  ruptured  lay 
transversely  and  was  removed,  the  placenta  separating 
with  but  little  hemorrhage.  Two  others  were  removed 
with  envelops  entire,  and  each  had  separate  placentae. 
The  umbilical  cords  were  duly  tied  and  cut,  and  efforts 
at  resuscitation  made,  which  Anally  were  successful. 
The  uterine  wound  was  closed  by  the  continued  suture 
of  fine  silk.  Some  delay  was  caused  by  hemorrhage 
from  the  divided  uterine  vessels,  which  finally  was  ar- 
rested by  hot  water.  The  peritoneum  was  sponged  clean 
and  dry  with  carbolized  warm  water,  and  the  incision 
closed  by  deep  interrupted  sutures  of  strong  silk.  No 
dressings  were  applied.  Duration  of  operation,  about 
thirty-five  minutes.  Before  the  question  may  be  raised 
as  to  whether  this  was  a  justifiable  operation,  permit  me 
to  *  let  the  cat  out,'  and  confess  that  this  patient  was 
only  a  cat !  And  I  might  also  here  venture  that  the  re- 
sult of  my  operation  ought  to  vindicate  our  profession 
from  the  charge  occasionally  made  against  some  of  its 
members  with  derision  by  some  evil-minded  laymen,  that 
*he  cannot  doctor  a  cat ! '  I  have  only  to  add  that  pussy 
was  carefully  nursed  by  watchful  little  friends  and  made 
a  speedy  recovery.  The  abdominal  sutures  were  re- 
moved a  week  afterward,  and  union  was  found  to  be 
complete.  The  kittens  that  were  *  untimely  ripped  from 
their  mother's  womb '  died  of  inanition  within  the  week. 
The  first-born  yet  survives,  however." 

The  Dram-Shop  Act  not  Applicable  to  Druggists 
IN  Illinois. — A  section  of  what  is  called  the  Dram-Shop 
Act,  passed  not  long  since  by  the  Illinois  I^egislature, 
provides  for  the  filing  of  a  bond  for  $3,000  by  any  sellers 
of  intoxicating  liquors,  and  it  has  been  a  question 
whether  this  applied  to  druggists  who  had  permits  to  sell 
for  medicinal,  chemical,  and  sacramental  purposes.  A 
case  of  this  sort  was  tried  in  Vermilion  County,  and 
it  was  held  that  druggists  were  bound  by  the  pro- 
visions of  the  law  like  all  other  persons.  An  appeal  was 
taken,  however,  from  this  decision,  and  the  Supreme 
Court  of  Illinois  has  just  reversed  this  decision,  holding 
that  druggists  are  exempt  from  the  bond.  It  was  also 
decided  in  the  same  case  that  where  a  village  ordinance 
prohibits  the  sale  or  giving  away  of  intoxicating  liquors 
within  the  village  limits,  but  allows  druggists  to  sell  for 
purely  medicinal,  chemical,  and  sacramental  purposes, 
if  there  is  no  provision  made  for  a  written  permit,  that 
the  ordinance  itself  is  a  permit  to  all  the  druggists  in  the 
village,  and  they  will  be  protected  in  selling. 

The  Druggists  and  the  Drug  Appraisers. — 
Charges  have  been  preferred  against  the  Appraiser's  De- 
partment of  the  Custom  House  in  this  city  by  a  number 
of  firms  importing  dye-stuffs,  drugs,  and  chemicals,  charg- 
ing that  they  are  hampered  and  injured  in  their  business 
by  the  unjust  discriminations  of  the  officials.  A  memorial 
has  been  prepared  and  sent  to  Congress  in  which  the 
importers  say  that  charges  of  undervaluation  are  contin- 
ually made  against  their  invoices,  which  charges  have 
been  shown  to  be  baseless,  and  that  as  a  result  they  are 
injured  in  business  and  reputation.  The  memorial  states 
"  that  while  canying  on  their  said  business,  and  in  all  re- 
spects, as  they  believe,  complying  with  the  laws,  they  are 
continually  obstructed,jhindered,  delayed,  and  embarrassed 
in  their  efforts  to  get  possession  of  their  goods  after  they 
have  passed  into  the  hands  of  the  customs  authorities  at 
this  port,  and  that  such  delays  and  hindrances  amount  to 
a  serious  interference  with  business,  causing  much  loss 


July  5, 1884-] 


THE  MEDICAL  RECORD. 


27 


and  damage.    .     .     .     That  it  frequently  happens  that 
goods  needed  for  speedy  delivery  are  held  for  one,  two, 
or  diree  months,  so  that  in  many  cases  the  importer  is 
prcrented  from  delivering  to  purchasers   according  to 
contract,  and  is  often  in  this  way  subjected  to  heavy  loss. 
That  the  undersigned  have  not  only  been  subjected  to 
the  delays  and  annoyances  aforesaid,  but  damaging  re- 
ports of  fraudulent  undervaluations  have  been  invented 
and  circulated  concerning  persons  in  their  trade  and  busi- 
ness ;  that  such  reports,  though  often  indefinite  and  vague, 
junount  to  an  imputation  of  fraud,  and  wrongfully  and 
unjustly  throw  suspicion  on  the  business  and  transactions 
of  the  undersigned  and  others,  and  that  such  charges  are 
made  by  United  States  officers,  and  have  appeared  and 
been  published  in  their  official  reports."      The  memorial 
concludes  by  requesting  that  an  investigation  be  had  into 
the  whole  matter,  under  the  direction  of  Congress.     The 
following  firms  are  the  signers  of  the  document :  W.  M. 
Pickardt  &  Kuttroff,  98  Liberty  Street ;  F.  Bredt  &  Co., 
26  Mun^y  Street ;  Lutz  &  Morius,  15  Warren  Street ;  J. 
C.  Bloomfield  &  Co.,  1 1  Dey  Street ;  Leisel  &  Halbach  ; 
W.J.  Matheson  &  Co.,  20  Cedar  Street ;  Geisenheimer  & 
Co.,  22  Liberty  Street;  E.  Selbach  &  Co.,  48  Cedar 
Street;  Schulze,  Berge  &  Koeck,  and  Baumig,  Bissell  & 
Co.,  22  Dey  Street.     It  is  thought  probable  that  an  in- 
vestigation will  be  ordered. 

"A  Good  Gen£Rall  Rule  of  Physvke." — Some  one 
has  hunted  up  from  an  old  book  called  "  Hundred  Mery 
Talys"  the  following  interesting  prescription:  "A  cer- 
tijn  artificer  in  LondA  there  was,  whyche  was  sore  seke 
and  coulde  not  well  dysgest  his  meat.  To  whom  a 
phjsicion  cam  to  give  hym  councell,  and  sayd  that  he 
mustvse  to  ete  metis  that  be  lyght  of  digestyon  and 
small  byrdys,  as  sparowes,  swalowes,  and  specyally  that 
bjrd  which  is  called  a  wagtayle,  whose  flessh  is  meruelouse 
lyght  of  digestyon,  bycause  that  byrd  is  euer  mouying 
and  styryng.  The  seke  man,  herynge  the  phesicion  say 
so,  answered  bym  and  seyd :  *  sir,  yf  that  be  the  cause 
that  those  byrds  be  lyght  of  dygestyon,  then  I  know  a 
mete  moch  lyghter  of  dygestyon  than  other  sparow, 
swallow,  or  wagtaile,  and  that  is  my  wyues  tong,  for  it  is 
oeaer  in  rest,  but  euer  meuying  and  sterryng.'  By  this 
tale  ye  may  leme  a  good  generall  rule  of  physyke." 

A  French  Compliment  for  Richmond. — A  Dr. 
Bougarel,  who  states  that  he  was  for  four  years  in  charge 
of  the  pest-house  in  Richmond,  Va.,  sends  to  Z^  Con- 
C9itrs  Medical  a  very  pleasing  account  of  the  state  of 
mescal  education  in  that  city.  There  are,  he  says,  one 
medical  college  and  two  hospitals,  one  for  the  blacks 
and  (me  for  the  whites,  but  the  medical  students  never  set 
ibot  in  the  hospitals,  gaining  their  practical  knowledge 
in  a  college  clinic.  At  the  end  of  two  years  (the  writer 
might  have  added  of  five  or  six  months  each)  these 
3«mg  gentlemen  start  out  armed  with  the  diploma  of 
doctor,  written  in  Latin,  with  the  Hippocratic  oath  printed 
adie  back.  Two  of  these  doctors  are  assigned  to  ser- 
m  in  the  hospitals,  and  there,  under  the  eye  of  the 
cftief  surgeon,  they  undertake  the  most  hstzardous  opera- 
tHBis.  They  do  not  appear  to  be  very  successful,  how- 
ever, for  the  veracious  writer  states  that  almost  all  the 
patieDts  die,  adding  by  way  of  explanation  that  ''  human 
life  counts  for  less  than  nothing  in  America."  Those 
iho  survive  the  operation  are  by  no  means  out  of  the 
woods,  for  they  are  then  turned  over  to  the  tender  mer- 
cies of  the  nurses,  who  apply  the  dressings  in  a  most  ele- 
mentary way  without  observing  the  least  precautions. 
The  doctors  in  the  meanwhile  are  walking  about  town  with 
Aeir  hands  in  their  pockets.  They  do,  however,  as  a 
matter  of  form,  visit  the  wards  once  a  day,  sometimes  in 
tut  morning,  sometimes  in  the  evening,  as  suits  their 
ODnvenience.  But  in  Philadelphia,  Dr.  Bougarel  con- 
tinues, medical  education  is  even  more  simple.  The 
candidate  begins  by  paying  down  twenty-five  dollars,  un- 
dergoes a  very  superficial  examination,  and  leaves  the 
college  fortified  with  a  diploma,   in  virtue   of  which 


he  may  henceforth  assassinate  with  impunity  those  whom 
his  attainments  attract  to  him.  The  writer  closes  with 
the  assurance  that  his  readers  may  rely  absolutely  upon 
his  statements,  for  he  has  cited  only  such  facts  as  he  has 
himself  observed.  Notwithstanding  the  outrageous  ex- 
aggeration of  Dr.  Bougarel* s  letter,  it  must  be  confessed 
that  his  account  rests  upon  some  foundation  of  truth,  at 
least  of  what  was  truth  at  the  time  of  which  he  writes. 

A  New  Method  in  Adherent  Placenta. — Dr.  W. 
W.  Jaggard  writes  to  the  Chicago  Medical  Journal  : 
"The  New  York  Medical  Record,  May  17, 1884, alludes 
to  a  report  in  the  Clinique,  by  Dr.  J.  Feld,  of  Kansas 
City,  on  *  A  New  Method  in  Adherent  Placenta.'  In 
six  cases  of  adherent  placenta,  the  life  of  the  woman  was 
saved  by  pumping  cold  water  through  the  umbilical  cord. 
Although  The  Record  is  in  error  in  its  denomination  of 
the  method  as  a  new  one,  it  deserves  credit  for  calling 
attention  to  a  very  old  and  very  excellent  procedure. 
The  injection  of  cold  water  into  the  umbilical  vein  in 
post-partum  hemorrhage  and  adherent  placenta  was  ably 
advocated  and  extensively  practised  by  Mojon  (1826), 
Kilian,  and  others.  The  umbilical  vein  is  divided  trans- 
versely, a  tube  or  quill  fastened  securely  in  the  proximal 
extremity,  and  cold  water  injected,  slowly  and  carefully, 
into  the  placenta,  by  means  of  an  ordinary  syringe.  The 
cold  water,  forcing  its  way  into  the  placenta,  distends 
that  organ  to  twice  its  original  volume,  escaping  through 
the  lacerated  utero-placental  vessels,  bathes  the  endome- 
trium, and  stimulates  the  uterus  to  powerful  contractions, 
usually  resulting  in  the  total  separation  and  spontaneous 
expulsion  of  the  after-birth.  Stoltz  and  Rombach  (1855) 
have  extolled  most  highly  this  measure,  while  Lin^ard 
(1875)  claimed  that  the  injection  of  150  grammes  of  pure 
cold  water  into  the  umbilical  vein  was  *the  best,  most 
reliable,  and  least  dangerous  expedient  in  all  cases  of 
postpartum  hemorrhage  or  adherent  placenta.'  At 
present  this  method  is  extensively  practised  in  Germany, 
more  particularly  in  Bavaria.  Scanzoni,  in  Wurzburg, 
practises  this  method  exclusively." 

Medicine  and  Medical  Men  in  Denmark. — The 
coming  meeting  of  the  International  Medical  Con- 
gress, to  be  held  in  Copenhagen,  makes  Denmark  just 
now  a  point  of  professional  interest.  The  Lancet  is 
publishing  a  series  of  letters  relative  to  this  question, 
from  one  of  which  we  extract  the  following  :  "  In  propor- 
tion to  the  population  of  Denmark,  the  number  of  Dan- 
ish medical  men  is  large,  as  is  the  case  in  almost  every 
country.  In  the  city  of  Copenhagen,  where  the  inhabit- 
ants number  some  two  hundred  and  fifty  thousand,  there 
are  more  than  three  hundred  and  fifty  doctors,  of  whom 
about  two  hundred  and  fifty  are  general  practitioners, 
the  remainder  being  mostly  either  young  medical  men  in 
the  hospitals  or  elderly  gentlemen  who  have  retired  from 
practice.  There  is  no  difference  made  between  surgeons 
and  physicians,  inasmuch  as  all  have  to  pass  the  same 
examination  at  the  University,  and  this  gives  the  whole 
profession  a  uniformity  which  does  not  exist  in  England. 
With  the  exception  of  a  few  specialists  and  surgeons, 
the  majority  of  medical  men  are  general  practitioners, 
and  it  is  customary  for  each  household  to  have  its  own 
doctor,  who,  in  return  for  his  services,  receives  a  fixed 
annual  fee  varying  in  amount  according  to  the  means  of 
the  family.  This  arrangement  is  attended  with  its  ad- 
vantages and  disadvantages,  but  is  generally  thought 
satisfactory  to  both  parties  concerned.  It  tends  to 
make  the  incomes  of  the  medical  men  more  fixed  and 
permanent,  and  it  affords  the  patient  the  opportunity  of 
calling  in  his  doctor  for  what  may  be  either  serious  or 
trifiing  complaints.  As  an  illustration  of  this  latter, 
there  is  a  trustworthy  story  of  an  elderly  lady  sending 
for  her  doctor  late  at  night  because  she  was  troubled  in 
her  mind  as  to  whether  it  would  be  prudent  for  her  to 
eat  a  baked  apple  the  first  thing  in  the  morning.  In 
Denmark  medical  men  hardly  ever  attend  normal  deliv- 
eries.    These  cases  are  left  entirely  to  midwives,  who 


28 


THE  MEDICAL   RECORD. 


[July  5,  1884. 


have  to  attend  a  midwifery  school  at  the  Lying-in  Hos- 
pital for  the  greater  portion  of  a  year,  and  then  to  pass 
an  examination  previous  to  being  allowed  to  practise. 
Of  late,  however,  there  has  been  a  movement  in  the 
medical  profession  in  favor  of  general  practitioners  un- 
dertaking these  cases,  though  as  yet  the  movement  has 
not  met  with  much  success.  A  change  which  would 
probably  meet  with  most  approval  would  be  for  educated 
ladies,  qualified  as  mid  wives,  to  undertake  these  cases. 
At  present  their  number  is  small.  The  social  position 
of  members  of  the  Danish  medical  profession  is  almost 
the  same  as  in  England,  excepting  that  there  are  very 
few  who  have  large  incomes  from  their  practice.  Fees, 
as  in  England,  are  here  considered  only  a  pium  disider- 
aium,  and  are  as  a  rule  much  smaller.  Consequently  a 
man  with  an  average  income  is  only  tolerably  well  off, 
but  as  wealth  is  more  equally  divided  in  Denmark  than 
in  England,  a  small  income  has  not  the  same  signifi- 
cance. While  one  meets  with  few  millionaires,  but  few 
paupers  are  to^be  seen.  One  observes  in  the  streets  of 
Copenhagen  nothing  approaching  the  luxury  in  the  out- 
ward appearance  of  life  which  prevails  in  England,  but 
at  the  same  time  one  does  not  encounter  rags  and 
misery,  and  such  a  thing  as  death  from  absolute  starva- 
tion has  hardly  ever  been  heard  of.  The  result  of  this 
financial  equality  is  that  money  has  not  the  same  im- 
portance attached  to  it  as  in  England,  consequently  that 
perpetual  struggle  to  keep  up  appearances  (an  expres- 
sion which  does  not  exist  in  the  Danish  language)  is 
unknown  here,  a  man's  education  rather  than  his  ac- 
count at  his  banker's  forming  his  passport  into  social 
circles.  There  exists  a  good  understanding  between  the 
Danish  medical  profession  and  the  general  public.  One 
very  seldom  hears  of  a  medical  man  being  judicially 
accused  of  faults  in  treatment,  and  a  fine  in  such  cases 
is  almost  unknown.  Such  a  thing  would  be  ruin  to  any 
practitioner,  as  his  case  would  soon  be  public  property 
in  a  small  country  like  Denmark.  There  is,  too,  a  de- 
cidedly good  feeling  among  the  members  of  the  profes- 
sion themselves,  at  least  in  Copenhagen.  There  are, 
however,  very  few  medical  societies  and  clubs,  partly 
owing  to  the  fact  that  clubs  do  not  flourish  in  this 
country,  and  partly  because  medical  men,  being  chiefly 
practitioners,  have  very  little  time  to  spend  outside  their 
homes.  This  is  also  the  reason  why  there  are  compara- 
tively few  Danish  medical  authors.*' 

A  Fine  Opening. — The  following  instructive  an- 
nouncement appeared  in  the  columns  of  the  Wiener 
Medicinische  Zeitung.  It  may  throw  some  light  on  the 
Austrian  social  system  :  "  To  Physicians  :-  A  young  single 
medical  doctor,  who  by  means  of  matrimony,  and  the  as- 
suming of  an  important  and  lucrative  dental  practice,  is 
inclined  to  found  a  very  agreeable  existence,  is  hereby 
given  an  opportunity.  A  yearly  income  of  10,000  guldens 
can  be  shown.  The  young  lady  concerned  is  the  daugh 
ter  of  very  respectable  parents,  seventeen  years  of  age, 
beautiful,  well-bred,  and  correspondingly  educated.  The 
father  wishes  to  retire  from  business,  and  will  deliver  to 
the  young  doctor  a  dental  practice,  dwelling  beautifully 
furnished,  together  with  material,  dental  tools,  and  in- 
struments to  the  value  of  8,000  or  10,000  guldens  en- 
tirely gratis.  Dental  knowledge  is  not  necessary  for  the 
beginning,  since  this  can  be  acquired  in  the  course  of  a 
few  months,  under  the  instruction  of  the  present  possessor. 
Applicants  address  *Zahnarzt,'  care  Editor  Allgem. 
Wiener  Med,  Zeitung^ 

Cremation  and  Burial  in  London. — Cremation  is 
regarded  with  but  little  favor  by  the  London  official 
mind.  Two  furnaces  have  already  been  built  under  the 
auspices  of  the  Cremation  Society,  and  as  Mr.  Justice 
Stephen  has  declared  from  the  bench  that  the  practice  is 
not  illegal,  more  are  shortly  to  be  constructed.  But  at 
South  Kensington  the  cremationists  have  been  refused  a 
stall  at  the  forthcoming  Health  Exhibition.  The  chair- 
man of  the  Health  Committee  does  not  approve  of  it. 


May  we  live  to  see  him  cremated  !  (after  death),  says 
the  Pall  Mall  Gazette,     The  latest  reverse  sustained  by 
the  votaries  of  "ashes"  is  the  decisive  negative  given  by 
Parliament  to  the  Cremation  bill.     This  bill  proposed  to 
regulate  cremation  and  place  it  under  proper  restric- 
tions, but  the  second  reading  was  negatived  by  nearly 
two  to  one.     Our  present  method  of  burial  is  insanitary 
in  the  manner  usually  adopted.     Many  of  our  metropol- 
itan cemeteries  are  in  the  centre  of  crowded  districts — 
even  those  of  modern  creation.     Brompton  Cemetery, 
for  instance,  is  now  surrounded  by  houses  on  all  sides, 
and  is  the  centre  of  a  densely  populated"  district.    It 
needs  no  very  lively  imagination  to  picture  the  possible 
— nay,  probable — effect  upon  the  dwellers  in  the  vicinity. 
It  has  been  shown,  too,  by  some  very  loathsome  practical 
experiments,  that  under  certain  conditions  the  human 
body  is  not  completely  disintegrated  and  resolved  into 
dust  for  a  good  many  decades.     About  five  or  six  years 
ago  a  very  ancient  city  burying-ground,  Bunhill  Fields, 
the  place  where  John  Bunyan  lies  interred,  was  sold  (!) 
to  a  well-known  firm  of  London  carriers,  who  obtained 
permission  to  build  stables  over  it  and  remove  such 
bodies  as  they  found  necessary,  they  engaging  to  re-inter 
them  elsewhere.     In  sinking  the  piles  whereon  to  erect 
their  buildings,  they  came  across  and  removed  a  large 
number  of  corpses.    Decomposition  had,  of  course,  com- 
menced, and  the  effluvia  was  overpowering,  but  some 
bodies  were  scarcely  disintegrated  at  all  and  presented 
an  almost  fresh  appearance.     A  Urge  number  of  bodies 
were  carried  away  as  dug  up  j'they  were  carried  on 
men's  backs,  who  were  plied  with  brandy  ad  libitum. 
The  details  may  be  mentally  realized  without  much  de- 
scription, and  the  danger  to  health  is  obvious.  This  affair 
was  hushed  up  as  much  as  possible,  and   I  believe  no 
notice  of  it  appeared  in  the  public  press  at  the  time.     I 
have  known  other  instances  of  graveyards  being  dis- 
turbed, to  the  danger  of  the  living  and  the  desecration  of 
the  dead.     It  is  not  lon^  since  it  was  proposed  to  as- 
phalt over  an  East-end  disused  graveyard  and  then  build 
on  it.    Nearly  all  our  large  railway  lines  run  through  one 
or  more  churchyards,  and  many  public  buildings  in  Lon- 
don have  been  literally  founded  on  the  tombs  of  our  an- 
cestors.    The  National  Gallery  is  one.     Some  of  these 
evils  would  doubtless  be  removed  if  "burning"  became 
common,  but  it  is  plain  that  even  from  a  scientific  point 
of  view  it  is  not  quite  free  from  objection.      It  hides  all 
trace  of  poison  and  other  modes  of  violent  death,  and 
renders  a  subsequent  '^  exhumation  "  impossible.      It  is 
legal  now,  and  it  is  thus  a  pity  the  bill  restricting  its  prac- 
tice did  not  pass»^^ 

Treatment  of  Angeiomatous   Growths. — Dr.  H. 
O.  Marcy  writes  in  the  Archives  of  Pediatrics  for  May, 
1884,  describing  a  method  used  by  him  for  the  removal 
of  naevi.     He  states  that  he  has  for  a  considerable  time 
employed  in    the   treatment  of  a  variety    of    vascular 
growths  a  suture  which  he  calls  "  the  shoemaker's  stitch." 
The  eye  of  the  needle  is  placed  near  the  point  which  is 
without  cutting  edges.     Armed   with   the    ligature    the 
needle,  which  is  set  in  a  strong  handle,  is  thrust  deeply 
under  and  quite  away  from  the  vascular  growth  ;  emerged 
from  the  distal  side  the  ligature  is  detached    and  the 
opposite  end  threaded,  when  it  is  withdrawn  and  again 
inserted  purposely  only  a  short  distance  from   the  first 
puncture,  since  it  is  important  to  include  only  a  com- 
paratively small  portion  of  tissue.     Thus  the   process  is 
repeated,  stitch  after  stitch,  until  the  entire   mass  is  en- 
closed and  the  fixation  is  completed  by  a  single  knot. 
In  this  way  uniform  and  steady  pressure  can  be  attained 
and  maintained  as  long  as  is  desired.     The  purpose  ol 
the  procedure  is  not  to  strangulate  and  cause  necrosis 
of  the  tissue,  but  to  constrict  so  as  to   reduce   to  the 
minimum  the  circulation  and  yet  preserve  its    integjrity 
The  author  claims  by  this  method  the  avoidance  of  th< 
unsightly  cicatrices  sometimes  resulting  from  the  cure  o 
angeiomatous  growths. 


The   Medical   Reci^j^^ 

-^   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  a 


New  York,  July  12,  1884 


Whole  No.  714 


©rigitml  %xXit\it^. 


SOME   REMARKS   ON    AFFECTIONS   OF  THE 
HEART. 

BT  J.  MILNER    FOTHERGILL,   M.D.  Edin.,   Hon.    M.D. 
Rush  Mkd.  Coll.,  III. 

Ajsocun  PKLLow  or  the  collsgb  or  fhysictans  op  fhiladklphia,  physician 

TO  TKB  OTY  OT  LONDON  HOSPITAL  POK  CXSKASBS  OP  THB  CHEST. 
II. 

VALVULITIS, 

Thx  ordinal^  impression  about  valvular  disease  of  the 
lieart  is  that  it  is  a  morbid  action  which,  once  set  on  foot, 
marches  steadily  and  resistlessly  onward,  the  valve  mis- 
chief getting  worse  and  worse  and  consequently  making 
fiirther  and  further  demands  for  compensatory  hypertro- 
{diy  until  the  S3rstem  fails  to  meet  the  demand,  and  then 
the  patient  dies  ;  and,  what  is  more,  that  this  is  a  com- 
paratively speedy  affair.  Such  possibly  is  correct  from 
the  point  of  view  of  the  dead-house,  and  is  borne  out  by 
mf  remembrance  of  the  Pathological  Institute  of  Vienna, 
bat  is  very  far  from  what  experience  of  practice  in  Eng- 
land  tells  me.  That  such  cases  do  occur  from  time  to 
time  may  not  be  denied,  and  a  marked  instance  came 
1  nnder  my  notice  rather  more  than  a  year  ago.  The  pa- 
tient was  an  athletic  man,  about  thirty,  of  good  family 
history,  who  was  playing  cricket  in  September,  1882,  and 
iho  died  with  valvular  disease,  both  aortic  and  mitral, 
die  latter  the  more  pronounced,  and  effusion  into  every 
yBXK&  cavity,  in  the  middle  of  January,  1883.  Here  the 
pcopess  was  terribly  swift.  I  can  also  remember  a  case 
in  isy  father's  practice,  where  rheumatic  fever  was  fol- 
ftwed  by  mitral  disease,  and  the  patient,  an  elderly  man, 
ded  with  dropsy  in  about  eighteen  months  from  his  first 
betDg  taken  ilL  But  I  unhesiutingly  deny  that  such 
cases  are  the  rule,  or  even  common ;  in  fact,  they  are 
rare— in  my  experience. 

This,  indeed,  is  valvulitis  as  seen  in  the  dead-house, 
lod  spoken  of  by  pathologists ;  but  it  is  not  the  valvu- 
libs  of  those  who  live,  crippled  indeed,  but  still  alive  and 
often  at  work.  The  prognosis  of  valvular  disease  is  very 
dfeent  now  from  what  it  was  held  to  be  among  earlier 
observers.  That  cases  running  their  course  swiftly  made 
ie  deepest  impression  on  these  pioneers  is  comprehen- 
Ue  enough.  But  there  is,  I  rejoice  to  say,  another  side 
Id  the  question,  and  that  side  will  now  be  presented  to 
Ie  reader. 

There  are  two  forms  of  valvulitis  which  must  be  clearly 
iferentiated  from  each  other  in  order  to  comprehend 
Ie  subject  properly.  There  is  (i)  acute  valvulitis;  and 
(1)  chronic  valvulitis. 

(i)  Acute  valvulitis. — This  may  be  the  result  of  rheu- 
irtic  fever,  to  a  lesser  extent  of  scarlatina  or  other  mal- 
ilf  of  early  life,  or  it^  may  be  set  up  by  violent  effort, 
Hbe  possibly  rheumatic. 

Here  there  is  an  inflammatory  storm  which  passes 
*er  the  serous  lining  of  the  interior  of  the  heart.  Be- 
kath  this  inflamed  serous  membrane  there  is  a  develop- 
lent  of  connective-tissue  corpuscles  into  the  structures 
Bderoeath  the  endocardium.  In  the  valve-curtains,  in 
ke  chordae  tendinae,  in  the  musculi  papillares,  there  is  a 
pnrth  of  soft  young  cells.  The  inflammatory  storm 
pees  away,  but  the  soft  young  cells  remain ;  and  pos- 
KKix^,  as  they  do,  an  inherent  tendency  to  contract  in 


no  long  time,  they  shrivel  up,  and  then  distortion  and  mu- 
tilation of  the  parts  in  which  they  exist  follows.  The 
valve-curtains  are  shrivelled,  may  be  dragged  down  to 
the  stumps  of  the  musculi  papillares  by  contraction  of 
the  tendinous  cords  ;  or  they  are  fused  together,  and  the 
mitral  valve  is  converted  into  a  fleshy  cone  with  a 
perforation  down  it,  extending  into  the  left  ventricle. 
Such  is  the  ruin  wrought  in  the  mitral  valve  by  this  de- 
forming process.  In  the  aortic  cusps  there  is  drivelling 
of  the  free  edges,  one  or  more  being  mutilated,  and  that 
more  or  less  severely  as  the  case  may  be.  But  once  the 
mischief  done,  it  remains,  like  the  cicatrix  of  a  bum, 
static  and  non-progressive.  A  certain  damage  is  done  to 
the  valve-curtains  which  cannot  be  undone,  and  which, 
as  we  saw  in  the  preceding  article,  is  compensated  (so  far 
as  the  powers  of  the  system  will  permit)  by  a  proportion- 
ate growth  of  the  wall  of  the  muscular  chamber  behind  the 
lesion. 

This  is  valvular  disease  of  the  heart,  as  it  has  presented 
itself  clinically  in  my  experience.  As  a  malady  of  child- 
hood it  is  infinitely  commoner  in  little  girls  than  little 
boys.  Some  die  of  dropsy  about  puberty,  others  live  on. 
In  one  instance  I  have  personally  watched  the  case  from 
about  the  age  of  eight  till  the  girl  is  now  twenty-six  years 
old,  a  village  schoolmistress,  who  gets  through  her  duries 
without  discomfort,  but  is  short  of  breath  on  effort,  as 
dancing,  and  who,  when  out  of  health,  is  apt  to  have 
some  oedema  about  her  ankles.  In  another  case  a  peas- 
ant had  rheumaric  fever  under  my  father,  with  mitral  re- 
gurgitation, about  twenty-eight  years  ago.  He  suffered 
at  times  from  severe  pulmonary  congestion  and  spat 
blood,  and  was  once,  indeed,  gravely  ill  under  my  care 
eighteen  years  ago.  At  that  time  he  had  to  work  for  a 
living,  but,  fortunately  for  .him,  he  got  some  money  left 
him,  which  enabled  him  to  live  without  toil,  and  since 
then  he  has  never  been  seriously  ill,  only  scant  of  breath. 
He  is  a  hale,  cheerful  old  man.  He  writes  me  at  the 
present  time  :  •*  I  don't  think  I  suffer  so  much  from  my 
heart  as  I  did  some  years  ago,  but  my  breathing  don't 
improve  with  old  age."  In  a  third  case,  that  of  a  well- 
known  authoress,  she  made  severe  efforts  abotit  fourteen 
years  ago  which  resulted  in  acute  valvulitis,  leaving  behind 
it  a  distinct  mitral  regurgitation,  which  makes  itself  felt 
only  on  effort.  While  she  is  at  her  desk  she  is  well.  She  is 
married  and  has  had  children,  but  her  literary  work  goes  on. 

So  much  for  mitral  cases.  A  distinguished  artist 
has  had  aortic  regurgitation  for  ten  years.  The  lesion 
is  a  moderate  one  and  the  ventricular  enlargement  is  not 
immense ;  he  leads  a  quiet  life,  and  is  not  measurably 
worse  during  the  last  six  years.  Some  time  ago  a  patient 
came  to  me  for  a  malady  in  no  way  connected  with  his 
heart,  who  had  distinct  aortic  regurgitation.  It  was  a 
small  lesion,  the  hypertrophy  was  not  great,  and  he  had 
worked  hard  as  a  solicitor  all  the  time  since  it  was  set  on 
foot,  seventeen  years  previously.  A  doctor-patient  of 
mine  had  a  considerable  aortic  regurgitation,  dating  back 
to  the  time  when  he  was  a  memcal  student  under  the 
famous  Stokes,  of  Dublin,  and  who  for  over  thirty  years 
had  worked  hard  in  practice — often,  indeed,  being  at 
death's  door — ^but  in  whom  the  valve  lesion  was  as  static 
as  the  Dead  Sea.  Such  are  some  of  the  aortic  cases 
which  have  come  under  my  notice.  Of  aortic  obstruc- 
tions it  is  unnecessary  to  speak ;  they  very  commonly 
run  on  for  years,  into  the  teens,  indeed,  in  several  cases 
known  to  me.  This  is  the  other  side  of  the  question — 
the  clinical  as  compared  to  the  dead-house  aspect ! 


30 


THE  MEDICAL  RECORD. 


[July  12,  1884 


(2)  Chronic  valvulitis, — ^This  is  a  totally  different  mal- 
ady. It  is  a  slow  progressive  disease  as  a  rule,  sometimes 
not  very  slow.  It  is  otherwise  known  as  sclerosing  endo- 
carditis. It  consists  of  a  parenchymatous  inflammation, 
or  cell-growth  into  the  valve-curtains,  and  earthy  salts 
may  be  deposited  in  the  neoplasm  when  the  condition 
spoken  of  as  ossification  of  the  valves  is  found.  At  other 
times  atheromatous  tubercles  are  found  springing  from 
the  surface  of  the  affected  valves.  Here  there  is,  speak- 
ing broadly,  usualljr  an  hypertrophied  ventricle  and  hard 
arteries,  with  firm,  mcompressible  pulse  and  a  loud  aortic 
second  sound.  In  other  words  there  is  "  the  gouty  heart. " 
There  is  a  high  blood-pressure  in  the  arteries,  the  ven- 
tricle overcomes  this  by  hypertrophic  growth,  and  by  the 
powerful  contraction  of  the  ventricle  the  mitral  valves 
are  closed  violently  and  so  become  chronically  inflamed, 
or  the  aortic  cusps  undergo  strain  from  the  powerful 
aortic  recoil,  and  a  cell-growth  is  instituted  in  them. 
This  form  of  valvulitis  is  essentially  progressive,  though 
the  rate  of  progress  is  by  no  means  the  same  in  each 
case.  The  muscular  changes  which  have  preceded  the 
valvulitis  must  be  entertained  in  these  cases,  as  well  as 
what  may  have  followed.  A  number  of  such  cases  have 
passed  under  my  observation,  from  the  pre-murmuric 
stage  of  accentuation  of  the  aortic  second  sound  to  the 
gradual  development  of  an  unmistakable  murmur,  and 
the  other  evidences  of  a  valvular  lesion.  In  one  case 
death  followed  within  eighteen  months  of  the  time  when 
no  murmur  was  to  be  heard,  and  was  due  to  aortic  valvu- 
litis. The  course  is  usually  not  so  swift.  For  four  or 
five  years  a  number  of  such  cases  have  been  under  ob- 
servation, but  all  are  marching  to  the  grave  at  a  measur- 
able rate.  Mitral  valvulitis  in  the  gouty  heart  does  not, 
I  am  inclined  to  think,  progress  so  quickly  as  is  the  case 
with  aortic  valvulitis,  at  least  usually.  In  one  case,  an 
old  medical  man  over  ninety,  there  was  mitral  stenosis 
which  ran  a  course  of  about  three  years,  so  far  as  is 
known,  accompanied  by  severe  angina  pectoris. 

There  is,  then,  a  totally  different  prognosis,  as  there  is 
a  totally  different  pathological  action  at  work,  in  cases  of 
progressive  valvulitis  to  what  there  is  with  the  static  in- 
jury  left  by  an  acute  endocardial  inflammation.  And 
it  is  therefore  a  matter  of  the  greatest  moment  to  dis- 
criminate which  affection  it  is  before  one  in  any  given 
case. 

Then  there  is  true  gouty  inflammation  of  the  valves  of 
the  heart,  well  described  long  ago  by  James  Wardrop. 
This  is  usually  the  progressive  valvulitis  just  described, 
but  cases  do  crop  up  where  the  process  is  rather  that  of 
the  acute  articular  gout  followed  by  a  period  of  quies- 
cence. Of  this  last  I  have  not  had  sufficient  experience 
to  speak  very  confidently. 

Of  ulcerative  endocarditis  my  experience  is  limited 
There  is  a  persistent  high  temperature  with  the  develop- 
ment of  a  murmur  ;  and  the  case  runs  its  course  with 
painfiil  celerity. 

These  two  last  forms  will  be  put  aside  in  the  following 
remarks,  which  are  confined  to  the  usual  forms  of  val- 
vulitis commonly  encountered  in  practice,  viz.:  the  static 
injury,  and  the  progressive  or  sclerosing  valvtditis. 

Having  determined  from  the  murmur  the  seat  of  the 
valvular  lesion,  according  to  the  rules  l«i^down  in  our 
text-books,  it  is  not  well,  in  my  opinion,'s^o  assume 
straight  away  that  you  have  to  deal  with  a  pit^essing 
valvulitis  which  will  soon  exhaust  the  power  0<  the 
organism  to  keep  pace  with  it  by  compensatory  hyp^cr- 
trophy  of  the  muscular  tissue.  That  such  is  at  times  th;R 
case  is  indisputable.  Having  decided  that  there  is  a  real 
lesion  there  are  some  other  points  to  be  ascertained. 

The  first  is  the  character  of  the  valvular  mischief ; 
whether  the  case  is  one  of  by-past  injury  without  any 
tendency  to  progress,  or  is  of  the  progressive  type.  This 
the  history  of  the  case  will  usually  determine.  If  the  pa- 
tient has  been  scant  of  breath  on  exertion  for  years,  then 
probably  the  lesion  is  old.  Perhaps  the  dyspnoea  on 
effort  dates  fi-om  some  comparatively  recent  illness,  may 


be  rheumatic  fever  ;  or  if  an  elderly  person  with  a  mitral 
lesion,  from  an  attack  of  bronchitis.  If,  however,  on 
the  other  hand,  the  patient  complains  that  recently  the 
breath  has  been  found  to  be  getting  short,  and  the 
murmur  has  got  the  wonted  concomitants  of  the  gouty 
heart,  probably  the  mischief  is  a  progressive  valvulitis. 
Not  only  your  prognosis,  but  your  treatment  will  be 
materially  influenced  by  the  character  of  the  lesion. 

The  second  is  its  extent.    Have  you  a  large  or  a  small 
lesion  to  deal  with  ?    The   amount  of  injury  inflicted 
varies  with  different  cases.     A  mitral  lesion  may  be  so 
small  as  only  to  make  itself  felt  on  considerable  effort ; 
or  it  may  be  such  as  to  necessitate  a  light  occupation  ; 
or  it  may  be  so  great  that  the  individu^  is  reduced  to 
the  condition  of  a  human  lizard,  incapable  of  active 
movement.    Such  a  case  I  have  in  the  hospital  at  present 
in  a  girl  of  fourteen.     Her  injected  cheeks,  her  blue  lips, 
her  hurried  respiration  alike  tell  of  a  large  mitral  lesion. 
The  congestion  of  the  pulmonic  circulation,  the  diminu* 
tion  of  the  thoracic  space,  and  consequently  the  neces- 
sity for  rapid  inspiration,  tell  far  more  as  to  the  extent 
of  a  mitral   lesion  than    does  the    character    of   the 
murmur.     Eloquent  as  to  the  presence  of  mischief^  the 
murmur  is  voiceless  as  to  its  extent.     That  must  be 
measured  by  other  evidence  than  that  furnished  by  the 
stethoscope.     Then  there  is  the  associated  condition  of 
the  muscular  wall     A  small  lesion  (no  matter  whether 
its  murmur  be  small  or  loud)  only  calls  for  moderate 
hypertrophy;  and   if  in  aortic    regurgitation   you  find 
little  (that  is,  comparatively  little)  ventricular  enlargement 
you  may  feel  pretty  certain  you  have  only  a  small  lesion 
before  you.    That  small  lesion  may  become  a  large  one ; 
and,  if  so,  the  enlargement  of  the  ventricle  will  tell  you 
very  distinctly  of  the  progress  of  the  valvulitis,  and  the 
amount  of  deformity  it  is  producing.     The  aortic  val- 
vulitis due  to  strain  progresses  at  a  very  different  rate 
in  the  university  oarsman,  who  gives  up  his  athletics 
and  settles  down  as  a  parish  priest,  married  and  sedate, 
to  that  exhibited  in  the  case  of  a  boatman  who  must 
work  hard  to  live.     Where  strain  is  continuously  thrown 
upon  the  parts,  the  progress  from  bad  to  worse  is  rapid. 
Where  a  quiet  life  is  led,  the  valvulitis  seems  to  come  to 
a  standstill     As  a  broad  rule,  then,  it  may  be  laid  down 
that  in  aortic  disease  the  size  of  the  left  ventricle  is  the 
best  guide  to  the  extent  of  the  disease.     And  another 
broad  rule  may  be  laid  down  alongside  this,  viz.:  the 
greater  the  enlargement  the  sooner  the  compensatisg 
hypertrophy  will  be  exhausted  ;  the  smaller  the  hyper- 
trophy the  longer  it  can  be  maintained     Consequently 
the  prospects  in  a  small  lesion,  if  static,  are  infinitely 
better  than  in  those  cases  where  die  lesion  is  a  lai^e  one. 

Beyond  these  matters  lies  the  question  of  the  condition 
of  the  muscular  fibrillae,  whether  well-fed,  ill-led,  or  the 
subjects  of  fatty  degeneration. 

When  a  patient  presents  himself  or  herself  before  a 
medical  man,  complaining  of  symptoms  which  point  to  a 
valvular  lesion,  and  such  is  actually  found,  it  does  not 
necessarily  follow  that  there  is  any  marked  change  going 
on  in  the  valvular  mischief.     This  may  be  the  case,  but 
by  no  means  necessarily  so.     The  valve-injury  may  date 
back  for  years,  but  it  is  only  recently  that  the  patient  has 
felt  worse  than  usual.     It  is  failure  in  the  muscular  wall  I 
There  has  been  sustained  over-demand  upon  the  heart ; 
or  there  is  a  history  of  defective  nutrition,  or  a  mixture 
of  both.    Commonly  it  is  found  that  the  necessity  for  toil 
has  made  the  patient  persevere  with  it,  disregarding  the 
uncomfortable  sensations  until  these  last  become  supreme, 
and  he  must  hie  to  the  doctor.    Or  times  have  been  bad, 
work  slack,  and  wages  small,  and  then  the  underfed  con- 
dition reveals  itself  in  loss  oif  vigor  in  the  restless,  ever- 
wocking  heart     Here  it  is  enough  to  lessen  the  demand 
upon  the  heart,  to  provide  a  sufficiency  of  nutritive  food, 
and  brace  up  the  heart-muscle  by  agents  which  increase 
the  vigor  of  its  contractions,  and  the  case  does  well.    The 
heart  improves  till  its  owner  can  once  more  work.      Or 
maybe  the  digestion  is  upset,  and  the  assimilation  of  al« 


July  12,  1884.] 


THE  MEDICAL  RECORD. 


31 


buminoidd  is  defective,  or  their  further  elaboration  by  the 

[iver  is  impaired  by  some  disturbance  of  that  viscus,  and 
then  tbe  heart  and  diaphragm  are  alike  underfed,  and  then 
the  symptoms  of  fiatty  degeneration  are  closely  simulated. 
And  such  is  the  explanation  of  many  a  sudden  break- 
down in  a  heart,  the  seat  of  an  old-standing,  non  pro- 
gressive valvular  lesion.  Here  attention  to  the  liver  is 
requisite  for  sufficient  tissue-nutrition.  In  other  cases 
there  are  not  merely  the  symptoms  of  fatty  degeneration, 
bat  other  evidences  of  tissue-decay  are  furnished  (a  mat- 
ter which  will  be  considered  in  the  next  article),  and  there 
ensts  no  reasonable  doubt  that  mural  decay  is  on  foot, 
resistless  and  irremediable.  When  assured  that  such  is 
the  case,  no  prognosis  can  be  too  dark. 

In  dealing  with  a  valvular  lesion  there  are  to  be  con- 
sidered (i)  its  site;  (2)  its  pathological  nature;  (3)  its 
extent ;  and  (4)  the  associated  condition  of  the  muscular 
walls;  not  only  diagnostically  but  prognostically  and 
thenpeutically. 

What  lessons  in  practice  does  pathology  teach  us  as  to 
the  treatment  of  valvulitis  P  It  tells  us  that  while  the 
inflammatory  storm  is  sweeping  over  the  endocardium 
tbe  most  perfect  rest  is  desirable.  Yes ;  but  its  study 
tells  us  more  !  It  tells  us  that  so  long  as  there  is  any 
cell-^wth  going  on  underneath  that  endocardium,  per- 
fect rest  should  be  maintained.  The  less  the  develop- 
ment of  the  connective-tissue  corpuscles,  the  smaller  the 
ultimate  deformity  caused  by  their  inevitable  contraction. 
To  limit  the  cell-growth  is  to  bound  the  resultant  lesion. 
So  clear  is  this,  that  no  roll  of  statistics  is  required  to 
prove  it  Perfect  rest  in  the  recumbent  posture,  the  sys- 
tem calmed,  and  the  blood-pressure  lowered  by  chloral  if 
necessary. 

Such  is  the  rational  treatment  of  a  case  of  acute  val- 
vulitis until  there  is  a  reasonable  assurance  that  the  day 
of  the  development  of  connective-tissue  corpuscles  is 
pt  and  over.  Limit  the  lesion  first  1  When  the  injury 
is  done,  the  process  of  mutilation  over,  then,  and  not  till 
then,  please,  comes  the  time  to  help  the  system  to  build 
up  the  necessary  compensatory  hypertrophy.  The  first 
line  has  to  be  inexorably  maintained  until  the  valvulitis 
is  or  has  been  brought  to  a  standstill.  To  get  a  patient 
who  has  been  the  victim  of  endocardial  inflammation  to 
make  one  unnecessary  effort,  is  to  drive  a  nail  into  his 
coffin.  In  progressive  valvulitis  quiet  is  desirable  so  as 
to  avoid  strain  on  the  diseased  valves.  In  both  cases 
d^italisy  which  increases  the  strain  on  the  valves,  is  con- 
ba^indicated  in  tbe  true  interests  of  the  patient  until 
heart-fiulure  sets  in.  When  a  gouty  element  is  present  in 
chronic  valvulitis,  then  a  non-nitrogenous  dietary  and 
Qii&acid  solvents  are  distinctly  indicated. 


I 


VaCHOW  UPON  THE  ChOLKRA  AND  TUBERCLE  Ba- 

cnius.— At  the  time  of  the  return  to  Berlin  and  public 
recepdon  of  the  Cholera  Commission,  Professor  Virchow 
nade  a  speech,  in  which  he  uttered  some  timely  words 
flfnming.  He  said  :  "It  appears  to  me  that  the 
Goremment  is  not  entirely  free  from  the  opinion  that 
with  &e  discovery  of  the  bacillus  everything  is  accom- 
plished which  may  be  necessary  to  control  the  disease. 
Id  this  connection  I  may  speak  a  warning  word.  It  is 
norc  than  thirty  years  since  we  discovered  the  little 
ngviism  which  causes  the  small-pox,  but  this  fact  has 
not  changed  in  the  least  the  practical  measures  pre- 
nously  adopted  for  its  prevention.  The  tubercle  baciU 
bs  18  a  very  important  thing,  but  with  the  exception  of  a 
new  point  of  view  of  the  disease,  which  is  given,  we  are 
no  farther  advanced  in  our  practical  relations  to  it."  He 
then  goes  on  to  say  that  the  cholera  has  for  some  time 
ban  practically  treated  as  though  it  were  caused  by  a 
J«cial  organism.  He  also  referred  to  the  laxity  of  the 
&giish  in  the  matter  of  quarantine. 

Hiccough. — A  sure  cure  for  hiccough  is  a  pinch  of  snuflf, 
warding  to  Dr.  P.  F.  Ellis,  in  the  Texas  Courier-Record. 


MANACA    IN    THE    TREATMENT    OF    RHEU- 
MATISM. 

Report  of  Fourteen  Cases. 

By    C.    M.    CAULDWELL,    M.D., 

VISITING  PHYSiaAN  TO  ST.  JOSBPH^S  HOSPITAL,   NBW  YORK. 

During  the  past  year  I  have  used  the  fluid  extract  of 
manaca  in  the  treatment  of  thirty-five  cases  of  rheuma- 
tism, and  have  come  to  regard  it  as  a  valuable  remedy 
in  certain  forms  of  this  disease.  The  drug  was  first 
brought  to  my  notice  by  Dr.  John  H.  Ripley,  who  had 
prescribed  it,  in  private  practice,  with  very  satisfactory 
results. 

As  the  information  to  be  gathered  concerning  the  ac- 
tion of  the  drug  was  rather  indefinite,  it  was  decided  to 
note  its  effect  upon  persons  in  health,  before  commenc- 
ing its  use  in  disease.  Accordingly,  two  healthy  men 
were  given  twenty  drops  of  the  fluid  extract,  five  times 
daily  for  one  week.  The  only  appreciable  effect  was  an 
increase  in  appetite  and  a  slight  *' valerian-like  "  odor  of 
the  urine  ;  otherwise  this  secretion  remained  unchanged. 
The  pulse  and  temperature  were  unaffected,  and  no  ab- 
normal sensations  were  produced. 

The  drug  was  now  prescribed  for  patients  suffering 
with  various  forms  of  rheumatism.  My  cases  differed 
widely  in  occupation,  habits,  and  social  position — some 
being  private  patients,  some  inmates  of  St.  Joseph's 
Hospital,  while  others  were  treated  at  the  New  York 
Polyclinic  The  ages  ranged  between  eleven  and  fifty- 
eight  years.  The  sexes  were  about  equally  represented. 
The  dose  of  the  fluid  extract — which  was  that  prepared 
by  Parke,  Davis  &  Co. — was  from  half  a  drachm  to 
three  drachms  a  day.  In  no  case  did  the  drug  disturb 
the  digestion,  while  in  several  instances  the  tongue 
cleared  and  the  appetite  improved  during  its  administra- 
tion. In  about  one-eighth  of  the  cases  frontal  headache 
or  a  sense  of  fulness  in  the  head  developed  after  the 
medicine  had  been  pushed  for  several  days. 

Manaca  was  used  in  but  two  cases  of  acute  articular 
rheumatism  with  high  temperature  ;  in  both  it  absolutely 
failed  to  relieve  the  pain  or  modify  the  fever. 

In  cases  of  chronic  rheumatism  it  frequently  gave  re- 
lief, and  in  a  few  instances  all  rheumatic  symptoms 
slowly  disappeared.  In  this  class  of  patients  my  results 
would  probably  have  been  better  had  the  dose  been 
larger,  as  Dr.  W.  S.  Gottheil  reports  (in  The  Medical 
Record  of  September  8,  1883)  seven  successes  out  of 
twelve  chronic  cases,  all  having  been  treated  with  large 
doses  of  the  drug.  The  doctor  usually  gave  six  drachms 
of  the  fluid  extract  per  day,  and  occasionally  as  much  as 
an  ounce  and  a  half  in  twenty-four  hours. 

By  far  the  most  satisfactory  results,  in  my  experience, 
were  obtained  in  cases  of  subacute  rheumatism,  in  which 
there  was  little  or  no  rise  in  temperature.  Fourteef 
patients  suffering  with  this  form  of  the  disease  were 
treated.  Twelve  recovered  and  two  received  no  benefit 
whatever. 

The  following  are  histories  of  the  cases  of  this  class  : 

Case  I.    Rheumatism  of  six  week^  duration  ;  recov-- 

ery  in  one  week;  two  relapses. — R.  J ,  twenty-one 

years  of  age,  plumber,  applied  for  treatment  February 
13th,  stating  that  for  six  weeks  he  had  been  unable  to 
work  on  account  of  rheumatism  in  all  the  larger  joints. 
This  was  his  first  attack  of  the  disease.  The  knees  were 
the  original  joints  involved,  but  the  pain  and  swelling 
had  constantly  shifted  from  one  articulation  to  another, 
at  the  same  time  increasing  in  severity,  so  that  now  it 
was  diflicult  for  him  to  walk  even  a  short  distance.  Ex- 
amination showed  moderate  redness,  swelling  and  tender- 
ness of  the  ankles,  left  knee,  and  right  elbow.  The  pa- 
tient's general  condition  was  exceUent.  Temperature, 
loof^.  No  cardiac  complication  present.  Manaca 
given  in  twenty-drop  doses  four  times  a  day. 

February  14th. — Considerable  improvement  has  taken 
place.  Both  swelling  and  redness  are  rapidly  diminish- 
ing.    Continue  treatment. 


32 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


February  19th.— ^The  patient  expresses  himself  as  per- 
fectly well,  being  entirely  free  from  rheumatic  symptoms. 
Ordered  to  continue  manaca  in  connection  with  tincture 
of  iron  for  ten  days  longer. 

Febniary  28th. — Patient  returns,  complaining  of  the 
same  trouble,  which  came  on  yesterday  while  working  in 
a  newly  plastered  room.  His  ankles  and  left  knee  are 
red,  hot,  and  swollen.  He  has  taken  no  medicine  since 
last  seen,  as  he  considered  it  unnecessary  **  to  drug  him- 
self when  hi  was  well.*'     Manaca  ordered  as  before. 

March  5th. — All  symptoms  have  again  subsided,  and 
the  patient  is  at  work.  He  refuses  to  continue  treat- 
ment, as  he  holds  that  "  medicine  is  for  the  sick,  not 
the  well." 

April  2d. — He  has  remained  in  perfect  health  up  to 
two  days  ago,  when  the  old  enemy  again  attacked  the 
ankles  and  knees.  These  joints  are  swollen  and  tender 
to-day.     Manaca  as  formerly. 

April  4th. — Rheumatism  has  subsided,  and  the  young 
man  is  now  willing  to  continue  any  medicine  prescribed. 
Manaca  and  iron  tincture  are  to  be  kept  up  for  two 
weeks. 

May  I  St. — There  has  been  no  further  relapse. 

Case  II.     /Rheumatism  of  thirty -six  hours'  duration; 

recovery  in  one  week, — R.  E.  C ,  aged  thirty-three ; 

actress.  Patient  was  first  seen  February  nth,  and  had 
then  been  in  bed  for  thirty-six  hours,  suffering  with  an 
attack  of  rheumatism,  which  had  involved  in  rapid  suc- 
cession the  left  shoulder,  elbow,  both  wrists  and  ankles. 
The  joints  of  the  upper  extremities  were  swollen,  hot, 
and  exceedingly  tender.  Temperature,  101°.  The  pa- 
tient was  thin,  anaemic,  and  in  very  poor  general  condi- 
tion. Considerable  cardiac  hypertrophy  and  a  well- 
marked  mitral  regurgitant  murmur  were  noted.  Thirteen 
years  before  she  had  "  rheumatic  fever  with  rheumatism 
of  the  heart,"  confining  her  to  bed  for  about  two  months. 
Since  had  often  had  mild  attacks  of  the  articular  affec- 
tion. Cardiac  palpitation  had  at  times  been  trouble^ 
some.  A  saline  laxative,  to  be  followed  by  twenty  drops 
of  manaca,  i\y^  times  daily,  was  ordered,  and  the  afifected 
joints  wrapped  in  cotton. 

February  14th. — The  patient  has  been  very  comforta- 
ble for  twenty-four  hours,  and  rheumatic  symptoms  are 
rapidly  subsiding.  The  temperature  is  normal.  Treat- 
ment continued. 

February  1 8  th. — Recovery  is  complete.     Manaca  and 
iron  tincture  are  to  be  continued  for  two  weeks. 
March  15th. — There  has  been  no  relapse. 
Case   III.     Rheumatism  of  three  week^   standing ; 

recovery  within  a   week;   relapse, — M.    W ,    aged 

twenty -five ;  porter.  Patient  came  under  observation 
February  19th.  He  had  then  been  unable  to  attend  to 
business  for  three  weeks  on  account  of  rheumatic  pains 
and  stiffness  in  knees,  elbows,  ankles,  and  wrists.  For 
two  days  the  right  knee  had  been  red,  swollen,  and 
somewhat  tender ;  a  week  previous  the  elbows  were  in 
the  same  condition ;  and  before  that  the  right  ankle  had 
been  the  troublesome  joint.  His  general  condition  was 
fair.  Temperature  normal.  He  never  had  rheumatism 
before,  but  both  parents  suffered  from  the  disease.  Or- 
dered manaca,  in  fifleen-drop  doses,  five  times  daily. 

February  25th. — All  his  symptoms  have  subsided  and 
he  is  at  work.     Is  to  continue  treatment  one  week. 

March  2d. — Patient  returns  with  his  former  complaint 
in  both  ankles  and  left  wrist.  He  neglected  taking  his 
medicine  as  directed,  thinking  the  precaution  unneces- 
sary. Last  evening,  after  exposure,  the  present  attack 
came  on.     Manaca  as  before. 

March  5th. — Patient  is  in  good  condition  once  more. 
Ordered  to  continue  medicine  for  ten  days,  and  then 
gradually  diminish  the  dose. 

Case  IV.  Rheumatism  of  five  weeks'  duration;  re- 
covery in  five  days, — M.  S ,  aged  thirty-five  ;  domes- 
tic. This  servant  was  first  seen  on  February  21st,  hav- 
ing then  had  rheumatism  for  five  weeks.  It  had  shifted 
from   one  articulation  to  another,   until   nearly   every 


joint  had,  in  turn,  been  stiff  and  painful,  but  never  in- 
flamed. In  spite  of  the  usual  anti-rheumatic  remedies 
she  had  not  improved.  Four  or  five  years  before  she 
had  a  similar  attack.  Her  general  condition  was  excel- 
lent.* Manaca  in  fifteen-drop  doses,  four  times  daily, 
was  ordered. 

February  23d. — Considerable  improvement  has  taken 
place  already.     Continue  treatment. 

February  26  th. — Reports  entirely  free  from  rheuma- 
tism and  feeling  very  well.  Ordered  to  continue  medi- 
cine one  week  longer. 

Case  V.  Rheumatism  of  six  weeks'  duration  ;  re- 
covery in  ten  days, — E.  O'C ,  aged  forty-nine,  house- 
keeper. The  patient  was  first  seen  February  26th,  having 
then  been  suffering  for  six  weeks  with  subacute  rheu- 
matism involving  the  knees,  elbows,  and  wrists.  For 
about  two  months  she  had  had  more  or  less  supraorbital 
neuralgia  and  been  greatly  troubled  with  acid  dyspepsia. 
For  three  years  she  has  been  subject  to  subacute  rheu- 
matic attacks.  Her  general  condition  was  fair,  but  ano- 
rexia and  insomnia  were  complained  of.  The  knees  and 
elbows  were  stiff  and  tender,  but  no  swelling  was  present. 
A  saline  laxative,  followed  by  twenty  drops  of  manaca 
four  times  daily,  was  ordered. 

February  28th. — No  improvement  in  the  condition  of 
joints.  Appetite  and  digestion  are  a  little  better.  Con- 
tinue treatment. 

March  2d. — Joints  are  much  better,  but  the  patient 
complains  bitterly  of  lumbago,  which  came  on  as  the 
joints  began  to  improve.  Continue  manaca,  and  apply 
sinapisms  over  the  lumbar  region. 

March  6th.— -Reports  free  from  both  lumbago  and  rheu- 
matism to-day.  Is  put  upon  full  doses  of  iron  tincture, 
to  be  continued  for  one  month. 

April  15th. — The  patient  was  looked  up  to-day.  She 
has  had  no  return  of  her  former  troubles,  but  keeps  a 
supply  of  manaca  on  hand  for  immediate  use  in  case  of 
returning  rheumatic  twinges.  She  is  also  treating  several 
of  her  rheumatic  friends  with  the  remedy. 

Case  VI.  Rheumatism  of  two  day^  standing ;  re- 
covery in  four  days, — C.  E.  K ,  aged  thirty-two,  cut- 
ter. The  patient  was  being  treated  for  phthisis  when, 
upon  February  28th,  he  was  attacked  with  pain,  tender- 
ness, and  stiffness  in  both  shoulders.  Within  twelve 
hours  these  symptoms  shifted  from  the  right  shoulder  to 
the  elbow  and  wrist.  As  his  lung  trouble  was  progressing 
favorably  it  was  decided  not  to  interrupt  the  antiphthisicsd 
treatment,  and  a  stimulating  liniment  only  was  ordered 
for  the  affected  joints. 

March  2d. — The  rheumatism  is  worse.  I^ast  night  the 
patient  was  very  restless  from  joint-pain.  Give  manaca 
in  fifteen-drop  doses  every  three  hours.  St6p  all  other 
medicines. 

March  6th. — Rheumatism  has  steadily  improved,  and 
to-day  is  fairly  gone.  Stop  manaca  and  return  to  former 
treatment. 

March  31st. — There  has  been  no  return  of  rheumatism. 
Case  VII.  Rheumatism  of  two  months  duration; 
recovery  in  one  week, — ^J.  C ,  aged  twenty-three,  en- 
gineer. Patient  applied  for  relief  February  28th,  com- 
plaining of  soreness  and  stiffness  in  the  muscles  of  the 
lumbar  region,  also  of  weli-marked  lameness  in  both 
feet  and  ankles.  The  ankles,  insteps,  and  toes  were 
swollen  and  tender  on  pressure ;  slight  redness  but  no 
heat  was  present.  No  other  joints  were  involved.  The 
young  man  had  several  previous  attacks  of  lumbago,  but 
never  had  articular  rheumatism  until  two  months  before 
coming  under  observation.  During  those  months  his 
lameness  gradually  increased,  although  in  fine  weather 
he  was  able  to  ^et  about  quite  well.  His  general  health 
was  good  in  spite  of  a  free  indulgence  in  tobacco  and 
alcohol. 

Total  abstinence  and  fifteen  drops  of  manaca  five  times 
daily  were  ordered. 

March  3d. — Reported  somewhat  relieved  of  rheuma- 
tism, but  suffering  with  a  severe  frontal  headache,  which 


July  12,  1884.] 


THE  MEDICAL  RECORD. 


33 


joiy  be  due  to  the  medicine  or  to  beer.  He  has  taken 
{)odi  faithfully.  Ordered  a  saline  laxative  and  manaca 
as  before^ 

March  7th. — Rheumatic  and  head   symptoms  have 
subsided  and  the  patient  has  returned  to  work.    'Is  to 
continue  treatment  for  one  week  and  report  any  re- 
lapse. 
Case  VIII.     Rheutnaiism  of  titree  weeks*  duration  ; 

wmca  a  total  failure, — M.  H ,  aged  thirty-five,  do- 

Bcstic.  For  fifteen  years  this  patient  has  had  repeated 
attacks  of  pain  and  stiffness  in  all  the  larger  joints,  but 
always  uDaccompanied  by  inflammatory  symptoms.  Dur- 
ing these  attacks  an  approaching  storm  renders  her  al- 
most helpless,  while  in  fine  weather  she  can  do  ordinary 
liousework  fairly  well.  Her  habits  were  very  bad.  In 
fact  she  was  intoxicated  when  first  seen,  and  was  suffer- 
ing from  gastro-intestinal  catarrh,  evidently  due  to  a  lib- 
eral use  of  beer  and  whiskey.  She  was  free  from  rheu- 
floatism  at  the  time.  Treatment  was  directed  against  the 
gastro-intestinal  disorder.  Upon  March  ist  she  began 
to  complain  of  general  joint-pain  and  stiffness,  but  as 
her  stomach  was  still  irritable  it  was  not  deemed  best  to 
institute  anything  in  the  way  of  internal  anti-rheumatic 
treatment.  The  troublesome  joints  were  rubbed  with  a 
stimulating  liniment  and  covered  with  flannel. 

March  13th. — The  gastric  trouble  is  much  better,  but 
DO  improvement  in  the  rheumatism  has  taken  place.  Ma- 
naa  in  twenty-drop  doses  five  times  daily  is  ordered. 

March  15th. — Pains  are  more  troublesome.  Rheuma- 
tism increasing  in  spite  of  improved  general  condition. 
Cbntinue  treatiuent. 
March  19th. — No  improvement.  Continue  treatment 
March  23d, — Rheumatic  symptoms  are  decidedly 
worse.  Stop  manaca ;  try  a  mixture  of  potassium,  io- 
dide, and  colchicum  wine. 

April  loth. — ^Patient  made  a  very  satisfactory  recovery 
upon  this  treatment. 
Case  IX.  Rheumatism  of  four  weeks'  standing ;  re- 

cmry  within  two  weeks, — H.  M.  S ,  aged  forty-five, 

artist  The  patient  was  first  attended  for  rheumatism 
apon  April  14th,  and  had  then  been  troubled  for  about 
one  month  with  aching  and  stiffness  in  all  the  larger 
joints.  An  approaching  storm  increased  these  symp- 
toms so  as  to  confine  him  to  his  room,  while  in  fine 
weather  he  was  out  of  doors,  free  from  pain  but  never 
quite  free  from  stiffness.  In  former  years  he  had  similar 
attacks,  but  of  shorter  duration.  His  appetite  and  gen- 
eral condition  were  poor.  Pills  of  iron,  quinine,  and 
stzTchnine,  with  twenty  drops  of  manaca  four  times 
^ly,  were  prescribed. 

April  17th. — Patient  thinks  he  is  a  little  better,  but 
seems  more  stiff  and  feeble  than  at  the  last  visit.  Con- 
tinne  treatment. 
April  21st. — Marked  improvement  has  taken  place 
king  the  last  two  days.  Only  trifling  stiffness  now  re- 
ims.    Same  treatment 

May  ist — Rheumatism  has  given  no   trouble   for  a 
Kvi   Stop  manaca  and  continue  tonic  pills. 
May  15th. — No  return  of  the  disease  up  to  date. 
Cask  X.    Rheumatism  of  four  day^  duration ;  re- 

tmrjin  two  days  ;  relapse, — T.  McK ,  aged  forty- 

fioQT,  merchant.  Patient  had  been  under  treatment  for 
phthisical  consolidation  of  the  left  apex  for  several 
veeks.  Upon  May  6th  he  was  exposed  during  a  pro- 
mise night-sweat,  and  the  following  day  was  confined  to 
bed  with  pain  and  stiffness  in  all  the  larger  joints,  espe- 
cially the  knees.  He  had  a  similar  attack  years  before. 
A  mixture  of  potassium,  iodide,  and  colchicum  wine  was 
oidered,  and  the  limbs  wrapped  in  flannel 

May  loth. — ^The  rheumatism  is  no  better,  and  the  pa- 
tient is  troubled  with  anorexia  and  insomnia,  being  un- 
able to  take  his  usual  exercise  in  the  open  air.  Treat- 
BMnt  changed  to  manaca,  twenty  drops  six  times  daily. 

May  1 2th. — Recovery  fi-om  rheumatism  is  complete. 
Kscontinue  manaca  and  return  to  antiphthisical  treat- 


May  1 6th. — A  relapse  occurred  to-day,  and  patient  is 
confined  to  bed.     Manaca  as  before. 

May  2 1  St. — Recovery  is  again  complete,  and  manaca 
is  to  be  continued  with  other  drugs  for  a  couple  of 
weeks. 

June  20th. — No  further  relapse  has  occurred. 
Case  XI.  Rheumatism  of  two  days*  standing;  recov- 
ery in  six  days, — M.  R ,  fifty-two  years  of  age,  ma- 
son. When  first  seen  upon  June  15th  the  patient  l^ad 
been  confined  to  bed  for  two  days  with  his  first  attack  of 
rheumatism.  The  knees,  especially  the  right,  were  hot, 
swollen,  and  exceedingly  painful  on  motion  and  pressure. 
The  ankles,  elbows,  and  wrists  were  also  involved  but 
less  severely.  Temperature  normal.  Appetite  and  gen- 
eral condition  good.  Wrap  the  joints  in  cotton  and 
take  twenty  drops  of  manaca  five  times  daily. 

June  17th. — ^There  is  no  change  in  the  case  except 
that  the  force  of  the  inflammation  is  now  felt  in  the 
shoulders  and  elbows,  the  knees  being  much  better.  In- 
crease dose  to  thirty  drops  five  times  daily. 

June  20th. — During  the  last  two  days  recovery  has 
been  rapid,  and  the  patient  has  spent  most  of  his  time 
out  of  doors.  He  complains  of  considerable  firontal 
headache,  which  came  on  yesterday  and  is  getting  worse. 
Reduce  dose  of  manaca  one-half. 

June  2  2d.-^The  patient  has  entirely  recovered  from 
rheumatism  and  headache.  Stop  manaca  and  take  iron 
tincture  for  two  weeks. 

July  15  th. — Patient  seen  to-day  ;  has  had  no  further 
rheumatic  trouble. 

Case  XII.     Rheumatism  of  a  day's  duration  ;  entire 

failure  of  manaca  to  relieve, — C,  J.  S ,  twenty  years 

of  age,  salesman.  Upon  July  loth  the  patient,  while 
under  treatment  for  phthisis,  fell  asleep  in  a  draught, 
and  shortly  afterward  was  seized  with  pain,  heat,  and 
swelling  in  the  left  shoulder  and  elbow-joints.  In  a  few 
hours  the  inflammation  shifted  to  the  ankles,  causing  well- 
marked  lameness.  There  was  no  rise  in  temperature. 
General  condition  was  bad.  Ordered  manaca  in  twenty- 
drop  doses  five  times  daily. 

July  1 2th. — The  joints  are  more  painful,  and  the  pa- 
tient more  irritable  than  when  last  seen.  Continue  treat- 
ment. 

July  15  th. — The  young  man  is  steadily  getting  worse 
and  is  now  confined  to  bed.  Ordered  the  dose  increased 
from  twenty  to  thirty  drops,  but  the  patient  refuses  to 
continue  the  drug  and  intimates  that  he  must  have  a 
change  either  of  treatment  or  physician.  He  has  a 
change  of  treatment,  and  a  mixture  containing  potassium, 
iodide,  and  colchicum  is  given. 

July  25th. — ^The  patient  has  slowly  but  steadily  im- 
proved since  the  last  note  was  made,  and  is  now  almost 
free  from  rheumatism. 

Case  XIII.  Rheumatism  of  twenty  four  hours!"  dura- 
tion ;  recovery  in  two  days, — T.  McG ,  aged  fifty- 
five,  carpenter.  For  fifteen  years  this  patient  has 
been  a  sufferer  from  chronic  rheumatism  to  a  greater  or 
less  extent  When  he  came  under  observation  he  had 
had  no  rheumatic  symptoms  for  six  months,  but  had 
been  much  troubled  by  cardiac  palpitation,  cough,  and 
dyspnoea.  Examination  showed  extensive  pulmonary 
emphysema,  chronic  bronchitis,  and  a  mitral  regurgitant 
murmur.  His  general  condition  was  fair.  Concen- 
trated nourishment,  rest,  and  a  mixture  containing  con- 
vallaria  and  quebracho  were  prescribed. 

Upon  September  15th  he  awoke  with  stiff,  swollen, 
and  painful  elbows,  wrists,  and  ankles.  During  the  day 
the  knees  became  affected,  and  muscular  rheumatism 
developed  in  the  lumbar  and  cervical  regions. 

September  i6th. — ^The  condition  remains  as  yester- 
day. All  former  medicine  suspended,  and  manaca  in 
twenty-drop  doses  five  times  daily  is  ordered. 

September  i8th. — The  more  acute  symptoms  have 
subsided,  leaving  only  stiffness — especially  of  the  knees. 
Iron  tincture  and  convallaria  are  to  be  added  to  the 
manaca  and  continued  for  two  weeks. 


34 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


October  15th. — The  above  treatment  has  been  carried 
out.     No  relapse  has  occurred. 

Case  XIV.  Rheumatism  of  two  weeks'  standing ; 
recovery  in  five  days, — C.  C ,  aged  eleven,  school- 
girl. Was  first  seen,  for  rheumatism,  upon  September 
2  2d.  For  several  days  she  had  complained  of  slight  stiff- 
ness and  soreness  m  the  knees,  shoulders,  and  neck. 
Her  general  condition  was  excellent.  Ordered  Dover's 
powder,  to  be  followed  by  small  doses  of  Rochelle  salt 
three  times  daily. 

October  ist. — The  joint-stiffness  and  soreness  has  not 
entirely  disappeared  at  any  time  since  last  note  was 
made,  and  to-day  it  is  worse  than  ever  before-  Ordered 
manaca  in  twenty-drop  doses  three  times  daily;  also 
clothe  the  child  in  flannel  undergarments. 

October  3d. — Considerable  improvement  has  taken 
place. 

October  5th. — Recovery  complete.  Continue  treat- 
ment for  one  week. 


VERATRUM  VIRIDE  AND  GELSEMIUM  IN 
THE  SUCCESSFUL  TREATMENT  OF  TET- 
ANUS. 

By  R.  B.    HARRIS,   M.D., 

SAVANNAH,   GA. 

The  pathology  of  this  most  formidable  malady  is,  to  say 
the  least  of  it,  limited,  and  as  yet  wrapped  in  some  ob- 
scurity. It  is  certain,  however,  that  the  symptoms  of 
tetanus  are  to  be  referred  to  an  unhealthy  action  in  the 
nerve-centres,  spinal  and  ganglionic,  -The  disease  has 
been  thought  by  many  writers  to  be  a  purely  reflex  phe- 
nomenon, and  although  the  writer  of  this  article  is  in- 
clined to  take  this  view  of  it,  yet  he  is  in  considerable 
doubt  as  to  its  truth.  In  support  of  this  theory  cases  of 
traumatic  tetanus  have  been  reported  where,  upon  the 
division  of  the  nerve,  the  spasms  have  ceased  and  the  pa- 
tient recovered. 

Macnamara  reports  a  case  in  which  he  saw  tetanic 
spasms  result  from  the  ligation  of  a  large  bleeding 
pile,  his  patient  being  attacked  with  spasms  of  the  sphinc- 
ter ani  muscle  within  thirty-six  hours  after  the  operation, 
and  although  the  ligature  was  immediately  removed,  the 
disease  ran  a  rapidly  fatal  course.  Many  cases  of  a  simi- 
lar character  might  be  noticed  here,  but  it  is  not  the  in- 
tention of  the  writer  to  discuss  the  pathology  of  tetanus 
in  this  paper  to  any  lengthy  extent.  There  are  many 
cases  of  tetanic  spasms  coming  under  our  observation 
where  it  is  impossible  to  refer  the  attacks  to  a  wound, 
abrasion,  or  apparent  injury  of  any  kind,  and  it  is  in 
these  cases  that  the  difliculty  arises  of  attributing  the  dis- 
ease to  reflex  action.  The  morbid  effects  in  this  class  of 
cases  may,  however,  be  set  up  by  some  source  of  irrita- 
tion in  the  mucous  tissues  or  in  the  glandular  system, 
and  therefore  hidden  from  view.  The  pathological 
changes  in  the  spinal  cord  after  death  from  tetanus  are 
said  to  consist  of  extensive  congestion  of  the  tissues, 
with  some  exudations;  but  the  question  arises,  and  a 
grave  one  too,  as  to  whether  these  changes  are  the 
causes  or  the  effects  of  diseased  nerve  action  ;  could  this 
question  be  satisfactorily  determined,  much  light  would 
be  thrown  upon  our  subject. 

It  is  unnecessary  for  the  writer  to  enter  upon  the 
symptomatology  of  tetanus,  except  as  to  temperature ;  a 
bare  mention  of  the  fact,  however,  suffices,  that  all  cases 
of  this  disease  which  have  come  under  his  observation 
have  exhibited  a  temperature  not  exceeding  loi**  F., 
and  this  while  the  heart's  action  was  as  high  as  130 
and  140  beats  to  the  minute.  The  main  object  of  this 
article  is  to  report  four  cases  of  tetanus  treated  by  the 
writer,  in  which  he  believes  recovery  due  to  the  adminis- 
tration of  veratrum  viride  and  gelsemium. 

Case  I. — W.  S ,  a  young,  vigorous,  and  plethoric 

man,  twenty-two  years  of  age.  Was  called  to  him  August 
II,  1867  ;  found  him  with  little  or  no  fever,  very  rest- 
less and  uneasy,  tongue  heavily  coated,  and  speech  a 


little  thick.     Upon  inquiry,  learned  that  two  weeks  since 
he  had  received  a  slight  injury,  from  which  he  had  suffered 
but  little.     Yesterday,   the    loth,   had  a  slight    spasm 
which  repeated  itself  this  morning  with  some  violence, 
and  occasioned  my  being  sent  for  in  haste.     After  get- 
ting this  much  of  the  history  of  the  case,  I  gave  one  grain 
of  sulph.  morphia  and  watched  my  patient  closely.     In 
about  one  hour  or  so  I  discovered  some  retraction  about 
the  scrobiculus  which  caused  a  slight  difficulty  of  breath} 
ing.     I  now  began  to  suspect  tetanus,  and,  fearing  this 
uneasiness    about  the   epigastrium    portended  another 
spasm,  I  gave  him  a  teaspoonfiil  of  laudanum.    (This 
case  came  under  my  treatment  before  the  hjrpodennic 
s)rringe  was  generally  used.)     I  examined  the  wound  he 
had  received,  and  found  nothing  but  the  cicatrix  of  what 
appeared  to  have  been  scarcely  more  than  a  scratch, 
just  above  the  patella  of  the  right  knee.     His  bowels  had 
not  been  moved  for  two  or  three  days,  I  therefore  had 
administered  two  ounces  castor  oil  and  twenty  grains 
calomel  in  combination.     I  now  noticed  considerable 
contraction  of  the  extensors  of  the  back,  and  some  rigid- 
ity of  the  entire  muscular  system ;  gave  two  grains  of 
gum  opii,  and  in  a  short  time,  seeing  that  a  spasm  was 
inevitable,  gave  a  teaspoonful  of  laudanum  with  the  hope 
of  keeping  it  off ;  but  in  half  an  hour  after  this  last  dose 
he  was  attacked  with  a  most  severe  spasm,  his  body 
forming  a  complete  arch,  and  lasting  ten  or  fifteen  min- 
utes.    As  soon  as  this  was  over  I  gave  him  two  more  tea- 
spoonfuls  of  laudanum,  which  I  got  down  with  some  diffi- 
culty; in  a  few  minutes  he  again  had  a  most  terrible 
spasm.     The  muscular  system  was  now  perfectly  rigid, 
the  jaws  firmly  closed,  and  the  hands  tightly  clenched, 
and  this  after  the  administration  of  four  teaspoonfuls  oif 
laudanum,  two  grains  of  opium,  and  one  grain  of  mor- 
phia in   four  hours.     The   pulse  now  ran   up  to   iio, 
and  somewhat  irregular.     Had  the  spine  and  extremities 
vigorously  rubbed  with  turpentine   and   mustard,   and 
enemas  of  salt,  soap,  and  warm  water  given,  but  without 
the  desired  effect.     Spasms  continued  at  short  intervals. 

August  1 2  th. — This  morning  patient  perfectly  rigid, 
pulse  140,  and  pupils  very  much  contracted.  The  tem- 
perature in  this  case  was  not  taken  for  want  of  a  ther- 
mometer. Having  given  all  the  narcotics  I  thought  was 
prudent,  I  determmed  to  change  my  tactics,  and  accord- 
ingly gave  patient  ten  drops  Norwood's  tine  veratrum 
viride,  and  having  had  his  head  and  shoulders  pulled 
over  the  edge  of  the  bed  with  a  large  tub  underneath,  I 
poured  four  large  pitcherfuls  of  cold  water  over  the 
head,  neck,  and  shoulders;  when  the  last  pitcherful 
was  being  poured  on  the  system  gradually  relaxed,  and 
my  patient  in  a  few  minutes  lay  seemingly  exhausted ; 
pulse  now  130  ;  pupils  contracted.  Two  hours  and  a 
half  after  the  first  dose  of  veratrum  I  gave  twelve  drops 
more.  At  three  o'clock,  now  three  hours  since  the  last 
dose  of  veratrum  was  given,  I  gave  another  of  twelve 
drops ;  in  one  hour  his  pulse  dropped  to  104,  and  he  fell 
asleep. 

At  6  P.M.  another  violent  spasm  came  on,  and  I  again 
resorted  to  the  cold  douche  with  equally  good  results  as 
before,  and  as  soon  as  the  spasm  ceased  I  gave  another 
dose  of  veratrum  combined  with  fifteen  drops  tine,  gel- 
semii.  (Tine,  gelsemii  was  made  of  the  green  root,  four 
ounces  to  a  pint  of  ninety-five  per  cent,  alcohol,  macer- 
ated for  fifteen  days  and  filtered;  the  tincture  made 
from  the  dried  root  is  almost  worthless.)  In  two  hours 
after  this  dose  was  taken  the  pulse  fell  to  68.  Patient 
now  perfectly  quiet  and  seems  much  better,  pupils  almost 
natural  size. 

Under  this  condition  of  things,  I  ordered  four  drops  of 
veratrum  (Norwood's)  and  eight  of  gelsemium  to  be  re- 
peated every  four  hours,  with  instructions  that,  should  a 
spasm  come  on,  the  cold  water  was  to  be  used  as  before. 

August  13th. — This  morning  (latient  seems  much  bet- 
ter ;  pulse  64,  skin  cool,  pupils  dilated,  but  tongue  very 
heavily  coated ;  ordered  an  enema  of  castor  oil  and  warm 
water,  which  brought  about  a  very  copious  action  of  the 


July  12, 1884.] 


THE  MEDICAL  RECORD. 


35 


bowels.  Discontinued  the  veratrum  and  gelsemium  and 
oniered  quinia  sulphate,  three  grains  every  three  hours. 
Was  sent  for  this  evening,  and  on  arrival  I  found  my  pa- 
tient in  another  violent  spasm.  I  at  once  applied  the 
cold  douche  as  above  mentioned,  and  as  soon  as  possi- 
ble administered  ten  drops  of  veratrum  and  fifteen  of  gel- 
semiuffl ;  in  a  short  time  the  muscular  system  became  re- 
laxed and  patient  more  quiet  After  waiting  two  hours 
I  repeated  the  last-mentioned  dose,  and  in  a  short  time 
after  had  the  satisfaction  of  witnessing  the  gradual  fall 
of  tbe  pulse  from  120  down  to  6S  beats.  I  now  ordered 
reratnim  and  gelsemium  to  be  repeated  and  continued  in 
four  and  eight  drop  doses  every  four  hours  until  my  re- 
loin. 

August  14th. — Patient  domg  well,  but  a  little  TduU ; 
coDtinued  last  prescription ;  pulse  60 ;  ordered  a*llight 
milk  punch  three  times  a  day. 

August  15th. — ^To-day  patient  is  brighter  and  calls  for 
oourishment ;  pulse  62,  pupils  natural,  and  tongue  clean- 
ing; takes  his  nourishment  readily,  but  complains  of  great 
stffi)ess  of  the  jaws ;  continue  prescription  as  above. 

August  2oth. — I  have  attempted  to  stop  the  veratrum 
and  gelsemium  twice  since  the  15th,  but  each  time  my  pa- 
tient evinced  sonie  spasmodic  symptoms,  and  I  returned 
to  them  in  combination  as  before,  with  positive  results. 

August  23d — Patient  improving  slowly,  is  very  much 
prostrated,  but  has  an  increasing  appetite.  Veratrum 
and  gelsemium  continued  in  three-  and  five-drop  doses 
every  four  hours  with  quinine. 

August  26th. — ^Patient  discharged  to-day,  with  in- 
stnictioDs  to  continue  the  medicine  for  five  days  longer, 
gradually  diminishing  the  dose. 

Case  II. — ^This  case  came  under  my  observation  June 
18, 1879,  ^T^^  ^^  a  case  of  idiopathic  tetanus  in  a  girl 
twenty  years  of  age.  When  I  first  saw  her  she  was  in  a 
most  violent  spasm,  no  portion  of  her  body  touching  the 
bed  on  which  she  was  lying,  except  her  heels  and  the 
back  (^  her  head.  I  immediately  resorted  to  the  cold 
douche,  but  without  the  same  happy  result  as  in  the  pre- 
ceding case  ;  the  efifect  was  good,  however,  and  I  soon 
had  an  opportunity  of  giving  Mteen  grains  of  calomel  and 
two  ounces  of  castor  oil  in  combination.  Tongue  very 
much  coated;  pulse,  126;  temperature,  99^;  respira- 
tion, 23.    Ordered  the  following  to  be  given  at  once  r 

9 .  FL  ext.  veratrum  vir 3  j. 

Fl,  ext.  gelsemii 3  iij. 

M.  S. — Give  fifteen  drops  in  a  little  water  every 
two  hours,  and  increase  each  dose  two  drops. 

Saw  her  again  in  four  hours  from  my  first  visit ;  had 
bad  two  spasms;  pulse,  112;  continue  prescription. 
Four  hours  from  last  visit,  no  more  spasm,  pulse  down 
to  40;  gave  a  tablespoonful  of  brandy,  shortly  after 
ibidi  the  pulse  rose  to  70.  Continue  prescription  in, 
tOHirop  doses  every  four  hours.  This  patient  was  up' 
n  seven  days,  but  continued  my  prescription  for  one 
vttk,  gradually  diminishing  the  dose. 

Case  III. — Negro  boy,  aged  eleven  years  ;  was  called 
to  him  December  14,  1881.  Upon  inquiring  into  the 
bistoiy  of  the  case,  I  learned  that  about  two  weeks  prior 
to  this  time  he  had  received  a  severe  blow  upon  the 
back;  on  examination  there  was  no  external  signs  of 
violence,  except  that  there  was  an  apparent  tenderness 
about  the  third  and  fourth  dorsal  vertebrae.  The  boy 
was  speechless ;  pulse,  as  well  as  I  could  count  it,  be- 
tveen  140  and  150 ;  temperature  (in  axilla),  100°  ;  ja]¥» 
io  firmly  closed  that  I  could  scarcely  insert  the  point  of 
the  blade  of  a  thin  case-knife  between  the  teeth,  and  a 
terrible  rigidity  of  the  entire  muscular  system.  In  this 
case  1  saw  no  hope  of  recovery,  but  in  a  few  minutes  I 
iad  a  course  of  treatment  laid  out  for  him,  and  lost  no 
time  in  putting  it  into  execution.  I  had  a  large  tub  of 
bot  water  brought  in,  and  emptied  a  common  size  (quar- 
ta-poand)  box  of  mustard,  and  a  half-pint  of  salt  into 
iti  and  pat  my  boy  in  up  to  his  neck  ;  while  he  was  in 
^  bath  I  had  another  smaller  tub  of  boiling  water 


brought  in,  and  into  this  I  put  a  laige  blanket ;  I  now 
gave  my  patient  five  drops  of  the  fluid  extract  of  gelsemii 
and  half  a  drop  of  the  fluid  extract  of  veratrum  viride  h)rpo- 
dermically.  After  being  in  the  balh  twenty  minutes  I 
had  the  blanket  in  the  boiling  water  wrung  out  and  spread 
upon  his  bed,  and  the  boy  immediately  rolled  in  it  up 
to  his  chin,  and  in  an  hour  after  repeated  my  hypoder- 
mic dose.  Some  discretion  should  be  exercised  in  roll- 
ing a  patient  in  this  blanket  taken  immediately  from  a 
tub  of  boiling  water,  as  there  is  danger  of  too  much  heat. 
Having  to  go  to  another  patient  I  returned  in  two  hours, 
feeling  that  I  would  not  be  surprised  to  find  him  dead ; 
but  to  my  astonishment  he  was  as  limp  as  an  old  wet 
rajg,  and  in  a  profuse  perspiration ;  pulse  98,  but  jaws 
still  firmly  closed.  I  ordered  castor  oil  and  warm  water 
enemas  to  be  ^ven  every  fifteen  minutes,  until  an  action 
was  had  on  his  bowels.  Saw  him  again  about  bedtime, 
six  hours  from  my  last  visit ;  bowels  well  acted  on ;  pulse, 
104 ;  gave  him  another  hypodermic  dose  of  veratrum 
and  gelsemii  and  rolled  him  in  another  hot  blanket  as 
before.  I  could  now  get  the  point  of  a  teaspoon  be- 
tween his  teeth.     Ordered  the  following : 

3 .  Fl.  ext.  veratrum  vir. 3  j. 

Fl.  ext.  gelsemii 3  iij. 

M.  S. — Give  ten  drops  in  a  little  water  every  four 
hours. 

December  15th. — Patient  improved  in  every  respect ; 
pulse,  84;  temperature,  99®.  When  spoken  to  he  an- 
swers with  a  nod  or  shake  of  the  head  ;  has  taken  some 
nourishment  Ordered  last  prescription  continued,  with 
the  addition  of  three  grains  of  quinine  every  four 
hours. 

This  case  progressed  to  almost  complete  recovery,  was 
up  and  walking  about  the  house,  when  suddenly,  from 
some  unknown  cause,  he  was  attacked  with  convulsions 
and  died  before  medical  aid  could  be  obtained,  on  De- 
cember 25  th. 

Case  IV. — ^J,  M ,   aged    fourteen  years;  about 

three  weeks  since,  this  boy  received  an  injury  on  the 
side  of  the  head,  caused  by  a  blow  which  had  cut  to  the 
skull.  His  father  told  me  that  about  two  weeks  after 
the  reception  of  the  injury,  he  had  noticed  that  the  pa- 
tient got  about  very  badly  and  would  occasionally  fall 
down. 

I  was  called  to  this  case  on  February  26,  1884 ;  found 
him  sitting  up,  but  having  regular  tetanic  spasms  every 
few  minutes;  pulse,  120;  temperature  very  little  above 
normal ;  jaws  partially  closed  and  rigid.  I  at  once  gave 
him  an  ounce  and  a  half  of  castor  oil  and  twelve  grains 
of  calomel  in  combination,  and  ordered  him  to  bed,  giv- 
ing his  mother  instructions  to  keep  warm  poultices  to 
the  wound  on  his  head. 

February  27th. — Patient  in  the  same  condition  as  when 
I  saw  him  yesterday,  except  that  his  bowels  have  been 
copiously  acted  on  by  the  calomel  and  oil.  Ordered  the 
following : 

5.  Fl.  ext.  veratrum  vir Z]- 

Fl.  ext.  gelsemii 3  iij. 

M.  S. — Give  fifteen  drops  in   a  little  water  every 
three  hours. 

This  evening  (February  27th),  pulse  down  to  48; 
gave  him  a  little  brandy  and  ordered  prescription  to  be 
continued  in  eight  drop  doses  tvety  four  hours,  with 
the  addition  of  three  grains  quinine  with  each  dose. 
Whenever  my  patient  was  sleepless  at  night  I  occasion- 
ally gave  a  few  grains  of  chloral  hydrate  and  bromide  of 
potassium,  but  with  this  exception,  there  was  no  other 
treatment  instituted  in  this  case,  which  progressed  to 
complete  recovery  in  fourteen  days. 

I  am  somewhat  in  doubt  as  to  die  therapeutical  action 
of  the  veratrum  and  gelsemii,  but  will  have  more  to  say 
upon  the  subject  in  the  near  future.  In  the  meantime  I 
earnestly  ask  the  profession  to  give  this  matter  their  seri- 
ous consideration  and  attention,  and  report  the  result?. 


36 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


WHEN    ARE  WE    AT    GREATEST   RISK  FROM 
CONSUMPTION  ? 

By  EDGAR  HOLDEN,  M.D.,  Ph.D., 

MBDICAL   DIRBCTORi   MUTUAL  BBNBFIT  LIFB  INSURANCE  CO., 
NSWARK,   N.  J. 

For  many  years,  even  among  the  best  informed,  the 
impression  has  prevailed  that  consumption  exhibits  a 


deductions  from  them  secure,  and  the  correspondence  of 
result  from  the  diverse  sources  enumerated  in  the  table 
can  leave  no  doubt  of  the  correctness  of  the  conclusion. 
The  experience  of  the  population  of  New  York  City, 
of  England,  and  of  the  United  States  in  general,  give  the 
results  for  unselected  lives  and  may  be  contrasted  with 
the  experience  of  life  insurance  companies  which  deal 
only  with  those  carefully  selected.  , 


CONSUMPTION. 

Showlf^lbfi  difimmce  benreea  actual  and  spparoil  martaO^ 
Ratio  to  •ub  10.000  Of  Ingt  FUtlo  of  ^••th  to  •$ch  100  deaths. 


aL4f 


Sl^O 


41410 


91*70 


^U 


JjSff^n^y 


N.  Y.  Qiiyy 


MMh,«U.f.y 


IQlifiQus.. 


ScoUemt 


iMMMlmM 


JUiuLBm^^ 


^^TTT 


II  i9.f?m.iif,t. 


N.  B,—  Ercpcr  cotidmlon  tan  b«;  tkiJKii  only  Jioai  tht  k&.  hand  lable^  and  u  as  folkiwt,  int. : 
ConsDiDptiaa  li  prcvalenl  aiall  peilDds  of  Me,  and  iDCEcaiea  laiher  tbaa  dkumKhsa  wSih  age.  Ffguies  iakf  t  TaMe  art  per  tofxia:  in  tigtU,  per  wa. 


preference  as  regards  development,  for  certain  ages. 
Thus,  it  has  been  the  conviction  that  those  who  escape 
the  marasmus  and  tubercular  meningitis  of  infancy  come 
again  into  danger  at  puberty,  and  that  again  between 
thirty-two  and  thirty-eight  a  climacteric  is  reached  at 
which  the  mortality  acquires  its  maximum  of  intensity, 
then  diminishing  to  declare  a  wholesale  sweep  between 
sixty  and  sixty-five. 

These  views  have  grown  out  of  an  experience  ap- 
parently well  founded,  since  the  mortality  in  every 
physician's  personal  field  of  observation  has  seemed  to  be 
greatest  at  those  periods,  but  the  conclusion  is  neverthe- 
less a  fallacy,  and  it  has  been  made  broader  and  deeper 
by  statistics  of  mortality  in  which  the  ratio  of  deaths  from 
consumption  to  the  total  number  of  deaths  has  been  re- 
lied upon. 

A  moment's  reflection,  however,  will  show  that  while 
we  may  judge  of  mortality  from  any  given  disease  with 
reasonable  accuracy  by  comparing  the  number  of  deaths 
with  the  total  number  of  deaths ;  yet,  for  individual  ages 
or  decades,  we  must  obtain  the  ratio  of  deaths  borne  at 
these  ages  to  the  total  number  living  at  those  ages. 

The  reason  for  this  will  be  obvious  from  the  fact  that 
a  far  greater  number  are  living  between  thirty  and  forty 
than  between  fifty  and  sixty,  and  consequently  there  is  a 
far  greater  harvest  for  this  most  prevalent  of  diseases. 

Rare  facilities  for  prosecuting  an  investigation  to  ob- 
tain a  correct  result  have  led  me  with  considerable  labor 
to  a  conclusion  as  startling  as  I  trust  it  will  be  found 
conclusive,  viz.,  that  death  from  consumption,  instead  of 
being,  as  is  almost  universally  supposed,  most  prevalent 
in  early  adult  life  in  this  country  is  in  reality  not  so,  but 
grows  relatively  more  frequent  as  life  advances.  This  is 
true  in  the  community  at  large,  and  among  selected  lives 
is  actually  less  at  the  ages  hitherto  deemed  most  sus- 
ceptible. 

The  figiures  dealt  with  have  been  so  large  as  to  make 


The  advantages  derived  by  these  companies  from 
selection  is  manifest.  The  right  hand  table  exhibits 
the  results  of  the  fallacious  figures  heretofore  deemed 
trustworthy. 

ON  THE  HEROIC  USE  OF  CALOMEL  IN  DIPH- 
THERIA AND  CROUP. 

By  I.  P.  KLINGENSMITH,  M.D., 

BLAIKSVILLB,   FA. 

After  having  given  the  ordinary  or  expectant  plan  of 
treatment,  including  iron,  quinine,  chloride  of  potash, 
lactic  acid,  stimulants,  etc.,  a  faithful  trial  for  eight 
years,  and  having  had  the  usual  high  mortality  rate,  I  be- 
^an  to  look  about  for  other  remedies  more  definite  and 
specific  in  their  action. 

About  this  time  Dr.  J.  W.  Anawalt,  of  Greensburg,  Pa., 
called  my  attention  to  the  success  of  the  calomel  treat- 
ment in  his  hands.  Since  then  three  cases  have  come 
under  my  personal  observation,  to  which  I  will  briefly 
call  attention.  In  each  of  these  cases  the  disease  mani- 
fested as  great  a  degree  of  malignancy  as  in  many  others 
treated  in  past  years  by  the  ordinary  methods,  which 
terminated  fatally. 

Ca^e  I. — On  Sunday,  April  10,  1883,  I  was  called  to 
see  Amos  McD ,  aged  twenty-eight  months,  of  pre- 
vious delicate  health.  Upon  examination  I  found  the 
pulse  rapid  and  irritable,  skin  hot  and  dry,  and  the  voice 
husky,  with  a  croupy  cough.  The  tonsils  and  a  portion 
of  the  fauces  were  covered  with  a  thick,  tough,  whitish- 
yellow  exudation  ;  while  the  glands  at  the  angle  of  the 
jaws  were  somewhat  enlarged  and  tender.  I  at  once 
ordered  twenty  grains  of  calomel,  which  was  followed  by 
ten  grains  every  hour,  until  the  third  day,  when,  the  mem- 
brane beginning  to  separate  at  the  edges,  the  mercurial 
was  discontinued.  During  the  first  three  days  of  the 
treatment,  a  total  of  seven  hundred  and  twenty  grains  ot 


July  12,  1884.J 


THE  MEDICAL  RECORD. 


37 


calomel  were  given,  after  which  a  solution  of  chlorate  of 
potash  was  administered  every  two  or  three  hours  for  a 
(ew  days. 

From  the  third  day  on  there  was  a  gradual  improve- 
ment in  the  case,  and  by  the  sixth  day  the  membrane 
bad  separated  entirely.  The  recovery  was  rapid,  and 
the  exhaustion,  so  common  in  cases  of  such  gravity,  was 
eniMy  absent 
Case  II. — On  the  afternoon  of  February  22,  1884,  I 

vas  called  to  see  Hulda  H ,  aged  three  and  one-half 

years,  of  hitherto  good  health,  who  had  then  been  sufifer- 
ing  for  forty-eight  hours,  during' which  time  she  had  slept 
bat  little. 

Upon  examination  I  found  a  temperature  of  102°  F., 
rapid  pulse,  hurried  respiration,  croupy  cough,  exten- 
sive deposits,  and  congested  face.  I  at  once  gave  her 
twenty  grains  of  calomel,  which  was  followed  by  ten 
grains  every  hour  for  fifteen  hours.  A  gradual  improve- 
ment of  the  symptoms  ensued  after  the  administration  of 
the  first  few  doses,  enabling  the  child  to  fall  into  a  natural 
refreshing  sleep.  After  discontinuing  the  calomel,  the 
following  mixture  in  drachm  doses  was  given  every  two  or 
three  hours  for  a  few  days : 

3.  Potass,  chlor gr.  xxx. 

Ammon.  mur gr.  1. 

Syr.  prun.  virg |  ij. 

M. 
By  the  fifth  day  convalescence  was  fully  established, 
and  the  child  made  a  rapid  recovery. 

Case  III. — I  was  .called  to  see  Alice  H y  aged 

four  years  on  May  8,  1884.  She  had  then  been  indis- 
posed  for  upward  of  twenty-four  hours.  An  examination 
revealed  a  high  temperature,  painful  croupy  cough,  la- 
bored respiration,  skin  dry,  face  flushed  with  some  diph- 
theritic ^posits.  I  immediately  administered  twenty 
grains  of  calomel  and  followed  with  ten  grain  doses  every 
hoar  until  twelve  doses  were  given,  making  a  total  of 
one  hundred  and  thirty  grains.  In  this  case  no  other 
remedies  were  used,  and  in  three  or  four  days  the  child 
had  fully  recovered. 

The  mercurial  used  in  these  cases  was  the  English  cal- 
omel, and  was  given  by  filling  a  teaspoon  half  full  of  cold 
water,  then  dropping  the  medicine  upon  it,  after  which  it 
was  placed  well  back  in  the  mouth  of  the  patient.  The 
calomel  purges,  but  not  to  excess,  causing  simply  free 
and  copious  evacuations  of  a  greenish  appearance.  I 
have  never  known  ptyalism  to  occur  in  a  single  case. 
My  experience  with  this  plan  of  treatment  is  based  upon 
die  three  cases  detailed  above,  besides  a  number  occur- 
ring in  the  practice  of  other  physicians.  I  am  not  one 
of  &ose  who  claim  to  cure  all  my  cases,  but  I  do  believe 
that  with  a  faithful  and  proper  administration  of  the 
remedy  in  question,  disintegration  and  separation  of  the 
nembranes  will  be  facilitated,  as  well  as  relief  afforded  to 
%  the  spasmodic  character  of  the  disease. 


Differential  Diagnosis  of  Simple  and  Tubercu- 
UK  Meningitis. — In  an  analysis  of  a  number  of  cases  of 
DKoingitis  occurring  in  the  Children's  Hospital  at  Stock- 
holm, Dr.  O.  Medin  endeavors  to  formulate  the  points 
of  diierence  in  the  tubercular  and  simple  forms  of  the 
&ease.  Tubercular  meningitis  attacks  only  those  chil- 
dren already  suffering  from  tuberculosis  of  other  parts, 
while  simple  acute  meningitis  occurs  usually  in  previously 
healthy  individuals.  Th6  former  manifests  its  onset 
bj  convulsions,  frequently  strabismus,  and  dilatation  or 
contraction  of  the  pupils.  Vomiting  is  frequent  at  the 
commencement,  diarrhoea  is  the  usual  condition,  and 
constipation  is  rare.  The  abdomen  is  iiever  flat.  The 
sunple  form  begins  with  somnolence,  twitchin^s,  sudden 
changes  of  color  in  the  face,  and  hypersesthesia.  More 
frequently  than  in  the  tubercular  form  we  meet  with  the 
i^^kocephalic  cry  and  paralysis  limited  to  the  arms  or  to 
the  hct.  The  tubercular  variety  is  always  fatal  in  its 
temunation — J^evue  MUicaUy  May  24,  1884. 


|^00tjeBfi  0f  ^jedicaX  JEicienuce* 

Splenectomy. — Dr.  Koeberl6  reported  to  the  Soci^t6 
de  MIdecine  de  Strasbourg  a  case  of  extirpation  of  the 
spleen  performed  by  him  in  April  last.  The  operarion 
was  performed  on  account  of  hypertrophy  consecutive  to 
intermittent  fever,  the  spleen  measuring  sixteen  inches 
in  length.  The  liver  was  also  greatly  enlarged,  and  there 
was  an  abundant  serous  exudation  in  the  pleural,  peri- 
cardial, and  peritoneal  cavities,  together  with  oedema  of 
the  lower  extremities.  Despite  difficulties  occasioned 
by  diaphragmatic  adhesions,  the  operation,  lasting  over 
three  hours,  was  successfully  performed.  The  patient, 
having  come  from  under  the  influence  of  the  anaesthetic, 
was  resting  comfortably,  when  suddenly  the  eyes  rolled 
convulsively,  a  few  long  inspirations  were  taken,  and  life 
became  extinct.  Death  was  supposed  to  have  been 
caused  by  an  intercranial  hemorrhage.— ^/^''^^^  dAc* 
couchementSy  May  30,  1884. 

Ergot  in  the  Treatment  of  Constipation. — Dr. 
Granzio  reports  two  cases  of  constipation,  following  the 
abuse  of  purgatives,  relieved  by  ergot.  Three  doses  of 
ten  grains  each  were  given  at  intervals  of  two  hours,  and 
were  followed  by  a  copious  evacuation.  A  second  stool 
occurred  spontaneously  the  next  day,  and  after  the  ad- 
ministration of  ergot  in  smaller  doses  for  a  few  days  a 
definite  cure  was  obtained.  The  constipation  was  due 
to  atony  of  the  muscular  wall  of  the  intestines. — Allge- 
meine  Mcdicinische  Ctntral-Zeiiung^  May  24,  1884. 

Chlorotic  Fever. — About  two  years  ago  Dr.  Hum- 
bert MoUi^re  and  F.  Leclerc  published  the  results  of 
some  thermometric  observations  made  by  them  in  cases 
of  chlorosis,  which  seemed  to  indicate  that  this  is  a  febrile 
condition.  Since  that  time  others  also  have  observed 
the  same  thing.  In  the  Lyon  Midical  of  May  25,  1884, 
Dr.  Mollidre  states  that  a  further  series  of  observations, 
in  some  cases  extended  through  a  period  of  eight  months, 
has  verified  his  previous  conclusions,  and  established 
definitely  the  fact  that  chlorosis  is  a  febrile  disease  and 
that  the  old  name  of  febris  alba  virginum  is  strictly  cor- 
rect The  temperatures  were  taken  with  scrupulous 
regularity  at  the  same  times  each  day,  and  always  by  the 
rectum.  In  most  cases  there  was  a  slight  evening  ex- 
acerbation, but  in  one  instance  the  reverse  obtained,  the 
mercury  being  higher  in  the  morning  than  in  the  evening. 
The  average  temperature  was  from  100®  to  1 01. 8®.  Care 
was  taken  to  exclude  all  cases  in  which  there  was  even 
a  suspicion  of  tubercular  trouble.  In  some  young  girls, 
who  were  'not  chlorotic,  but  were  simply  anaemic  from 
overwork  or  poor  food,  no  elevation  of  temperature  ex- 
isted. In  all  the  cases  of  true  chlorosis  there^was  a 
cephalic  souffle,  audible  over  the  eyes  on  a  level  with 
the  temples,  and  in  some  instances  in  the  occipital  region. 
This  souffle  was  synchronous  with  a  systolic  murmur 
heard  at  the  base  of  the  heart  and  with  bruits  in  the 
vessels  of  the  neck.  The  febrile  action  was  always  in 
proportion  to  the  intensity  of  the  disease,  subsiding 
gradually  as  the  chlorotic  condition  disappeared.  The 
urine  in  the  cases  examined  was  of  normsd  amount,  very 
light  colored,  sometimes  containing  a  slight  cloud  of 
mucus,  and  never  presenting  any  excess  of  urea  above 
the  normal  quantity.  Dr.  Molli^re  leaves  undecided 
the  question  as  to  the  nature  of  this  constant  febrile  re- 
action, whether  it  be  a  true  pyrexia  or  of  nervous  origin, 
but  inclines  to  the  former  opinion. 

Antipyresis  by  Inunction. — Colbat  favors  a  revival 
of  the  old  method  of  Schneemann  of  inunctions  with  fat 
or  vaseline  in  the  febrile  diseases  of  childhood.  He  uses 
cerate  or  vaseline  in  scarlatina,  variola,  broncho-pneu- 
monia, and  other  pyretic  conditions,  and  states  that  it 
reduces  the  temperature  and  induces  a  condition  of  rest- 
lulness.  He  denies  that  there  is  any  danger  of  blood- 
poisoning  in  the  employment  of  these  inunctions. — Medu 
cinisch'Chirurgisches  Corresponden%-Bl(Ut^  May,  1884. 


38 


THE   MEDICAL  RECORD. 


[July  12,  1884. 


BoROPHENYLic  AciD. — ^A  new  series  of  experiments  has 
recently  been  made  to  determine  the  antiseptic  value 
of  this  substance.  Borophenylic  or  phenylboric  acid  ap- 
pears in  the  form  of  bushy  needles,  slightly  soluble  in  cold 
water,  but  freely  so  in  hot  water,  alcohol,  and  ether.  It 
has  a  faintly  aromatic  odor,  recalling  that  of  marjoram. 
It  has  no  caustic  action  upon  the  mucous  membranes, 
even  when  applied  in  the  form  of  powder,  but  excites 
merely  a  slight  irritation.  In  fifteen-grain  doses  it  causes 
ringing  in  the  ears,  vertigo,  moderate  headache  and 
somnolence.  Its  antipyretic  properties  are  said  to  be 
undoubted,  and  it  would  appear  to  be  of  greater  efficacy 
than  carbolic  acid  in  arresting  fermentation  and  putrefac- 
\on.— Journal  de  Mddecine  de  Bruxelles^  May,  1584. 

Production  of  Paralysis  without  ANiGSTHssiA  by 
Peripheral  Irritation.— Brown-S6quard,  in  experiments 
upon  guinea-pigs,  has  found  that  when  chloral  is  applied 
to  the  external  auditory  canal  complete  muscular  par- 
alysis without  loss  of  consciousness  is  induced.  When 
chloral  is  injected  into  the  stomach  the  same  efifect  is 
observed,  though  in  a  less  marked  degree.  In  every 
case  the  loss  of  the  power  of  voluntary'  movements  pre- 
ceded anaesthesia  and  sleep.  The  experimenter  supposed 
that  a  special  influence  was  exercised  upon  the  nervous 
centres,  through  irritation  of  the  auditory,  auricular,  or 
other  peripheral  nerves,  whereby  muscular  movement 
was  abolished  without  loss  of  sensibility. — Gaceta  Midica 
Catalana^  May  31,  1884. 

Repeated  Attacks  of  Vomiting  in  Children. — This 
affection  is  one  of  early  childhood.  Vomiting  occurs 
in  attacks,  coming  on  at  varying  intervals  of  time  and 
lasting  from  a  few  hours  to  several  days.  The  little 
patients  are  often  greatly  debilitated.  There  is  fre- 
quently pain,  sometimes  intense,  in  the  epigastric  or 
umbilical  region.  The  stools  are  irregular,  sometimes 
abundant,  sometimes  scanty,  and  may  be  whitish  or  clay- 
colored.  The  causes  are  variable.  The  attacks  may 
be  due  to  exhaustion,  to  a  nervous  condition,  to  im- 
proper nourishment,  or  to  the  influence  of  cold.  As 
regards  treatment,  a  low  diet,  with  or  without  chicken 
broth,  is  advised,  and  in  addition  calomel  in  small  doses 
should  be  exhibited — L  Union  Medicate  du  Canada^  No. 
3,  1884. 

Prophylaxis  of  Puerperal  Fever. — In  his  report  of 
the  Rotunda  Hospital  for  1883  {Dublin  Journal  of  Medi- 
cal Science^  June,  1884),  Dr.  A.  V.  Macan  recites  in 
detail  the  method  in  vogue  in  that  institution  for  the 
prevention  of  puerperal  hetero-infection.  Vessels  con- 
taining a  I  to  40  solution  of  carbolic  acid  are  placed 
over  every  wash-hand  basin,  and  every  one,  before  mak- 
ing a  vaginal  examination,  is  required  to  wash  his  hands 
in  the  solution,  using  a  nail-brush  carefully,  and  after- 
ward dips  them  for  half  a  minute  in  a  i  to  1,000  solution 
of  corrosive  sublimate.  Every  student  or  nurse  who  ex- 
amines a  woman  per  vaginam  has  to  write  his  or  her 
name  down  on  a  card,  so  that  if  the  patient  should 
afterward  prove  to  be  infected  the  origin  of  the  infection 
may  be  traced  Only  four  students  are  allowed  to  ex- 
amine any  given  case,  and  none  who  is  dissecting  is 
allowed  to  enter  the  hospital.  There  is  an  absolute  rule 
against  touching  the  woman's  genitals  with  the  fingers 
after  delivery,  except  in  cases  of  post-partum  hemor- 
rhage, ruptured  perineum,  or  retained  placenta,  and  then 
the  assistant  master  only  is  allowed  to  make  the  examina- 
tion. If  any  operation  be  necessary  the  vagina  is  irrigated 
and  the  external  genitals  are  carefully  washed  in  a  i  to 
2,000  corrosive  sublimate  solution,  and  afterward  the 
uterus  is  syringed  out,  and  a  suppository  containing  3  jss. 
of  iodoform  is  passed  to  the  fundus  and  left  there.  Dr. 
Macan  sees  no  necessity  for  prophylactic  antiseptic  in- 
jections if  the  fingers  and  instruments  are  perfectly  free 
from  septic  poison,  and  consequently  never  uses  them. 
Out  of  1,090  women  confined  during  the  year  but  six 
died,  and  all  these  deaths  followed  more  or  less  com- 


plicated labors.  Not  a  single  woman  died  who  had  a 
natural  labor,  nor  was  there  a  death  among  the  64  cases 
of  forceps  delivery,  many  of  which  were  difficult  extrac- 
tions, and  some  undertaken  before  the  full  dilatation  of 
the  OS.  In  the  same  report.  Dr.  Macan  states  that  the  tem- 
perature of  every  case  was  taken  twice  daily,  and  that  he 
was  unable  to  recognize  any  constant  rise  of  temperature, 
even  to  the  extent  of  one  degree,  accompanying  the  first 
secretion  of  the  milk.  Indeed,  the  temperature  curve 
of  the  puerperal  state,  in  a  typical  normal  case,  does  not 
appear  to  differ  in  the  slightest  degree  from  that  in  the 
non-puerperal  state.  He  is  inclined  to  believe  that  any 
temperature  above  100**  F.,  except  immediately  after 
delivery,  indicates  that  something  abnormal  is  taking 
place,  though  it  may  not  always  be  possible  to  say  what 
the  exact  cause  of  the  rise  may  be. 

Hypodermic  Injections  of  Calomel  in  Diseases  of 
the  Eye. — Dr.  Rampoldi  injects  calomel  subcutaneously 
over  the  temples  in  certain  ocular  troubles.  He  main- 
tains that  there  is  not  only  a  specific  action  in  the  case 
of  syphilitic  affections,  but  that  it  also  acts  most  efiica- 
ciously  as  a  derivative  in  other  cases.  He  has  seen  the 
pupil  respond .  readily  to  atropine  after  these  injections 
had  been  used,  when  before  they  were  unchanged.  The 
good  eflfepts  of  this  procedure  are  often  observed  in  those 
conditions  in  which  leeches  are  indicated  in  which  there 
is  no  suspicion  of  a  specific  taint. — RecueU  ^Ophtal- 
mologie^  May,  1884. 

A  New  Apparatus  for  the  Relief  of  Deafness. — 
Professor  Politzer  describes  in  the  Wiener  Medizinischt 
Wochenschrift  of  May  31,  1884,  a  little  instrument  in- 
vented by  himself  to  aid  those  whose  power  of  hearing 
is  impaired.     The  principle  is  to  transmit  the  vibrations 
from  the    pinna   to  the   membrana   tynapani.     Politzer 
opposes  Voltolini's  opinion  that  the  cartilage  of  the  ear 
is  a  poor   conductor   of  sound,  and   on  the  contrary 
believes  that  the  pinna,  by  means  of  its  vibrations,  is  of 
great  importance  in  the  mechanism  of  hearing.     His  ap- 
paratus consists  of  a  small  elastic  drainage-tube,  one 
end  of  which  is  beveled  off  so  as  to  rest  evenly  against 
the  drum  membrane,  while  the  other  end  is  curved  slightly 
and  by  its  elasticity  presses  gently  against  the  anti-helix. 
Near  its  outer  extremity  the  tube  is  attached  to  a  small 
concavo-convex  rubber  plate.     This  plate  is  fitted  so  that 
its  concave  side  lies  in  apposition  with  the  concavity  of 
the  concha.     The  idea  of  this  attachment  is  to  increase 
the  conducting  power  of  the  instrument  and  to  transmit 
with  greater  facility  the  vibrations  of  the  pinna.     In  a 
large  number  of  experiments  made  to  test  the  value  of 
this  instrument,  the  inventor  found  that  in   most  cases 
the  hearing  distance  for  the  voice  was  considerably  in- 
creased, in   some   instances  fi-om  two  feet   without  to 
fifteen  or  twenty  feet  with  the  apparatus.     In  many  cases 
the  hearing  distance  for  the  watch  was  'also   increased, 
though  in  no  such  striking  degree  as  that  for  the  voice. 
In  cases  in  which  the  drum  membrane  was  partially  or 
entirely  destroyed,  it  was  found  necessary  to  attach  an 
artificial  drum  to  the  inner  extremity  of  the  tube.     In 
deafness  due  to  anchylosis  of  the  ossicles  or  to  disease 
of  the  labyrinth,  little  or  no  improvement  was  obtained 
by  the  employment  of  the  tube. 

Action  of  the  Intercostal  Muscles. — M.  Laborde 
has  recently  performed  some  experiments  upon  the 
cadaver  of  an  executed  criminal  which  would  seem  to 
have  solved  the  problem  concerning  the  action  of  the 
intercostal  muscles.  The  body  was  obtained  a  very 
short  time  after  death,  while  the  electrical  reaction  of 
the  muscles  was  still  present.  M.  Laborde  ascertained 
that  contraction  of  the  internal  intercostal  caused  a 
narrowing  of  the  thoracic  cavity,  while  that  of  the  ex- 
ternal muscles  caused  an  elevation  of  the  ribs  and  an 
expansion  of  the  chest.  Hence  the  external  intercostals 
are  muscles  of  inspiration,  and  the  internal  of  expira- 
tion.— Revue  Midicale^  May  24,  1884. 


July  12.  1884.J 


THE  MEDICAL  RECORD. 


39 


A  New  Edition  of  thb  Siamese  Twins. — A  case  is 
reported  io  the  Hospitals- Tidende  of  May  21,  1884,  of 
twins  bom  in  a  parish  in  Finland  Each  child  has  its 
oiro  bead  and  the  two  upper  extremities.  From  the 
united  body  two  normally  shaped  legs  are  given  off,  and 
between  them  is  the  single  genital  organ  (female).  In 
addition  there  is  a  third  leg,  the  foot  of  which  is  provided 
with  eight  toes.  There  are  two  anal  openings.  While 
one  child  sleeps  the  other  may  be  awake  and  cr3nng. 

Paraldehyde  in  the  Treatment  of  Delirium 
Tremens. — Dr.  Gugl  reports  some  additional  cases  of 
delirium  tremens  treated  successfully  with  paraldehyde. 
The  dmg  was  given  in  the  syrup  and  tincture  of  orange 
peel,  and  was  taken  readily  by  the  patients,  the  taste  and 
smell  leading  them  to  regard  it  as  a  particularly  good 
quality  of  schnapps.  The  author  asserts  that  paralde- 
hyde is  absolutely  without  danger  in  the  dose  of  i^  to  2 
drachms  per  diem. — Allgetneine  Medicinische  Central-- 
Zeitung,  May  28,  1884. 

Variations  in  the  Size  of  the  Pupils  in'Epileptics. 
—As  a  result  of  a  number  of  observations,  Dr.  Giuseppe 
Mnsso  concludes  that :  i,  The  pupils  of  epileptics  do  not 
dilate  to  any  greater  extent  than  do  those  of  healthy  in- 
dividuals ;  2y  in  a  large  proportion  of  cases  there  is  an 
habitual  dilatation  of  the  pupils  of  greater  or  less  degree ; 
5,  in  a  certain  number  of  cases  the  epileptic  attacks  are 
preceded  by  an  inequality  in  the  size  of  the  pupils,  which 
inequality  disappears  when  the  fit  is  over ;  4,  although  in 
certain  cases  of  epilepsy  inspection  shows  a  greater  sen- 
sitiveness of  the  pupils  to  the  stimulus  of  light,  yet  this 
phenomenon  is  not  of  sufficient  frequency  to  be  of  any 
special  diagnostic  value. — Recueil  tP  Ophtalmologie^  May, 
1884. 

The  Dosimettric  Method  of  Administering  Chlo- 
roform.— M.  Peyraud  takes  a  piece  of  fine  cambric,  and 
doubling  it  once,  lays  it  on  the  face  of  the  patient  to  be 
anaesthetized,  covering  only  the  mouth  and  nose.  On  the 
litde  bridge  of  cloth  passing  from  the  nose  to  the  mouth 
he  poiirs  a  single  drop  of  chloroform,  waits  until  an  in- 
s(»ntioQ  has  been  made  and  then  pours  another  drop, 
and  so  he  proceeds,  putting  on  just  one  drop  immediately 
after  eadh  expiration.     At  the  end  of  some|  minutes,  if 
anaesdiesia  is  dela]^ed,  he  increases  the  dose  to  two  drops. 
Complete  insensibility  is  obtained  ordinarily  in  from  seven 
to  ten  minutes.     The  writer  claims  that  aniesthesia  is 
produced  by  this  method  without  any  preliminary  stages 
of  agitation  and  hyperaesthesia,  and  without  the  occurrence 
of  any  irregularity  in  the  pulse  or  respiration.     When 
once  anaesthesia  has  been  obtained  he  withholds  the  chlo- 
roform for  a  minute  or  two,  and  then  resumes  its  admin- 
istiation  in  the  average  dose  of  three  drops  per  minute. 
The  patients,  it  is  said,  find  the  chloroform  given  in  this 
way  not  at  all  disagreeable  to  inhale,  and  so  small  is  the 
proportion  of  chloroform  in  the  inspired  air  (the  vapor 
cf  one  drop  to  30.5  cubic  inches),  that  there  cannot  pos- 
fll%be  anything  to  disturb  the  functions  of  haematosis 
or  to  irritate  the  respiratory  mucous  membranes.     M. 
Pejraud  cites  several  instances  in  which  anaesthesia  was 
produced  and  maintained  during  an  operation  with  very 
small  amounts  of  chloroform.     In  one  case  of  an  hys- 
terical woman  on  whom  an  operation,  lasting  an  hour 
and  a  half,  was  performed  for  cancer  of  the  kidney,  only 
6^  drachms  of  chloroform  were  used.     It  is  assumed  that 
Ae  danger  of  arrest  of  the  heart's  action  is,  in  this  pro- 
cedure, reduced  to  a  minimum.— y^t^r/ia/  de  Midecine  de 
hrieaux. 

In  abstracting  this  article,  a  writer  in  the  Gazette 
Mldicale  de  Strasbourg^  of  June  i,  1884,  states  that  the 
Wmetric  method  has  been  in  vogue  in  that  city  for 
nanj  years.  Esmarch's  apparatus,  consisting  of  a  wire 
mask  covered  with  a  piece  of  fine  linen  and  fitting  over 
tiic  mouth  and  nose,  is  used.  The  air  passes  freely 
Arongh  the  wire  gauze  on  each  side,  while  the  linen 
JtfTes  to  hold  the  chloroform.  A  contrivance  is  also 
enplojred  by  means  of  which  the  anaesthetic  can  be  .de- 


livered drop  by  drop,  with  perfect  accuracy,  as  required. 
The  writer  is  in  perfect  accord  with  M.  Peyraud  as  re- 
gards the  great  advantage  possessed  by  this  method  of 
administering  chloroform.  He  states  that  in  a  laparotomy 
recently  performed,  anaesthesia  was  maintained  for  three 
hours  wirti  the  expenditure  of  one  ounce  of  chloroform. 

Tubercular  Neuralgia. — In  an  article  in  La  France 
M^icale  of  May  29  and  31,  1884.  Dr.  Ferdinand  Drey- 
fous  states  that  neuralgias  are  observed  in  tuberculous 
subjects  in  three  different  stages  of  the  disease,  i.  In 
the  terminal  stage  they  are,  in  the  majority  of  cases,  to 
be  attributed  to  the  cachexia  which  is  a  recognized  cause 
of  neuralgia  in  other  conditions.  2.  During  the  course 
of  well-established  phthisis  we  often  observe  intercostal 
neuralgia,  or  even  tuberculosis  of  the  phrenic  or  pneu- 
mogastric  nerve.  In  these  cases  the  painful  nerves  are 
m  more  or  less  intimate  connection  with  the  organ  chiefly 
affected.  3.  Finally,  in  the  initial  period  we  may  meet 
with  peripheral  neuralgias  in  various  parts  of  the  body, 
but  by  far  the  most  common  is  sciatica.  It  is  not  usually 
very  troublesome  and  is  frequently  overlooked  by  reason 
of  the  attention  being  directed  chiefly  to  the  general 
condition.  It  is,  hQwever,  not  at  all  infrequent  at  this 
period  of  commencing  tuberculosis,  and  has  even  been 
described  as  one  of  the  early  symptoms  of  the  dis&se. 
Sciatica,  when  occurring  at  this  stage,  is  usually  unilateral, 
a  point  of  some  diagnostic  value,  since  neuralgias  of 
diathetic  or  toxic  origin,  as  in  diabetes  and  plumbism, 
are  more  commonly  bilateral  and  symmetrical.  The 
sciatic  nerve  is  more  frequently  affected,  it  is  supposed, 
partly  because  of  its  large  size  and  partly  by  reason  of 
its  relatively  abundant  vascularity,  which  exposes  it  to 
greater  danger  of  colonization  by  the  micro-organisms. 

Funnel-Shaped  Thorax. — Dr.  F.  Percival  relates  an 
instance  of  this  curious  deformity  in  the  Rivista  Clinica 
for  May,  1884.  The  subject  was  a  man,  forty  years  of 
age,  whose  family  history  showed  a  predisposition  to 
phthisis,  and  one  of  whose  sisters  showed  evidences  of 
marked  rachitis.  He  had  himself  always  been  healthy, 
and  two  children  of  whom  he  was  the  father  were  per- 
fectly sound.  The  malformation  of  the  chest  had  existed 
since  birth,  but  had  never  caused  any  inconvenience  on 
the  part  of  either  the  heart  or  lungs.  The  excavation, 
shaped  like  a  truncated  cone,  began  at  the  junction  of 
the  manubrium  with  the  sternum,  and  ended  below  at  a 
distance  of  about  five  inches  above  the  umbilicus.  One 
could  put  his  closed  fist  in  the  depression,  and  at  first 
sight  it  seemed  as  though  the  sternum  must  touch  the 
spinal  column.  The  greatest  depth  was  three  inches, 
and  the  distance  from  this  point  to .  the  spinal  apophyses 
was  scarcely  four  and  a  half  inches.  The  aperture  of  the 
depression  was  of  an  oval  shape,  measuring  six  inches  in 
length  and  four  and  a  half  in  width.  It  was  situated  a 
little  more  to  the  right  than  to  the  left  side  of  the  thorax. 
Posteriorly  there  was  a  slight  degree  of  kyphosis  of  the 
vertebral  column,  but  no  lateral  deviation.  Dr.  Percival 
thought  that  the  cause  of  the  deformity  was  probably  an 
arrest  of  development  in  the  sternum,  possibly  due  to  a 
disease  of  the  bones  allied  in  its  nature  to  the  rachitis 
from  which  one  of  his  sisters  had  been  a  sufferer. 

Tubercles  of  the  Breast. — The  following  are  the 
conclusions  formulated  by  Dr.  Ghislani  Durant  in  an 
article  with  the  above  title  {Gaillards  idedical  Journal y 
June,  1884) :  i.  The  breasts  may  be  the  seat  of  tumors 
similar  to  the  pathological  products,  found  in  many  other 
organs,  to  which  the  name  of  tubercle  is  given.  2. 
Tubercle  in  the  mammary  gland  is  much  more  common 
than  is  generally  supposed.  3.  Mistakes  as  to  the  true 
nature  of  these  growths  have  often  been  made,  and  abla- 
tion of  the  breast,  from  a  belief  in  their  cancerous  nature, 
has  often  resulted.  4.  During  life  we  may  by  clinical 
observation  distinguish  these  from  other  tumors.  5.  As 
no  absolute  necessity  for  the  ablation  of  these  tumors 
exists,  we  should  refirain  firom  operating,  unless  unequiv- 
ocal signs  of  malignanqr  develop. 


40 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


The  Medical  Record 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co..   Nos.  56  and  58  Lafayette  Place. 

New  York,  July  la,  1884. 

CHOLERA  AND  ITS  PREVENTION. 

The  report  that  cholera  has  appeared  in  a  seaport  town 
of  Europe  sounds  a  note  of  warning  which  the  health 
authorities  of  the  United  States  would  do  well  to  heed. 
It  Ts  possible  that  the  European  States,  with  their  expe- 
rienced  boards  of  health  to  guide  them,  and  their  well- 
equipped  sanitary  police  to  execute  their  orders,  may 
prevent  the  spread  of  the  pestilence  on  the  continent. 
But  whatever  precautionary  measures  foreign  govern- 
ments may  take  to  protect  themselves,  it  will  be  the  part 
of  prudence  to  examine  at  once  our  own  defences,  and 
take  such  measures  as  will  secure  us  against  an  invasion 
of  the  Oriental  scourge.  For  we  are,  in  truth,  but  little 
less  exposed  to  an  invasion  of  cholera  than  the  cities 
contiguous  to  Toulon,  owing  to  the  constant  emigration 
of  the  lower  classes  of  that  and  other  seaport  cities  of 
the  Mediterranean  to  this  country. 

If  we  examine  our  methods  of  preventing  the  intro- 
duction and  spread  of  contagious  and  infectious  diseases 
of  foreign  origin  in  the  light  of  modern  science,  knowl- 
edge, and  experience,  we  can  but  conclude  that  they  are 
cumbersome,  expensive,  and  inefficient.  Indeed,  we  do 
not  hesitate  to  state  that  for  the  most  part  our  machin- 
ery for  protection  against  foreign  epidemics  was  con- 
structed, and  is  managed,  in  the  spirit  and  enlightenment 
of  the  middle  ages.  .  Our  quarantine  system  is  still  too 
much  governed  by  the  old  idea,  that  time  is  the  most  im- 
portant element  in  the  destruction  of  the  contagious  or 
infectious  germ,  and  that  non-intercourse  is  the  true 
method  of  preventing  the  propagation  of  the  germs  of 
epidemics. 

Within  the  past  two  years  the  old  cordon  saniiaire, 
which  is  but  another  name  for  the  shot-gun  quarantine, 
has  been  the  chief  reliance  of  the  highest  functionary  in 
this  country  to  prevent  the  spread  of  yellow  fever. 
Within  the  same  period  a  vessel  having  on  board  hun- 
dreds of  emigrants  suffering  from  small-pox,  has  been 
detained  in  quarantine  until  the  disease  had  completed 
its  work,  not  a  person  being  allowed  to  leave  the  ship  in 
the  meantime.  This  is  only  another  method  of  enforcing 
the  old  dogma  of  non-intercourse,  and  is  closely  allied 
to  the  cordon  sanitaire  and  the  shot-gun  quarantine. 

The  inadequacy  of  our  present  measures  of  prevention 
will  become  apparent  if  we  reflect  for  a  moment  upon 
the  present  teachings  of  science  as  to  our  power  to  de- 
stroy in  their  incipiency  the  very  germs  of  the  diseases 
against  which  we  create  and  maintain  our  costly  and 


well-nigh  useless  quarantines.     If  cholera  be  taken  as  an 
example,  we  can  readily  determine  how  far  in  advance  of 
our  practice  are  the  requirements  of  sanitary  science. 
We  now  know  that  cholera  can  never  invade  this  country, 
except  the  germs  are,  first,  in  the  digestive  organs  of  a 
human  subject ;  or,  second,  are  in  his  clothing,  goods, 
or  other  effects  where  they  have  been  lodged.    With  this 
knowledge  as  our  guide,  how  simple  and  effective  be- 
come all  of  our  preventive  measures  !     We  aim  to  ef- 
fect two  objects,  viz.,  first,  to  destroy  the  germ  ;  and 
second,  to  prevent  its  introduction  into  the  human  stom- 
ach.   The  first  is  accomplished  by  the  use  of  well-known 
germicides,  and  the  second  by  care  that  neither  by  water, 
food,  unclean  hands,  or  other  means,  the  germ  enters 
the  mouth.     With  a  proper  appreciation  of  these  simple 
yet  fundamental  facts,  we  may  apply  preventive  meas- 
ures with  precision.    The  cholera  germ  can  be  sought 
out  and  destroyed  as  absolutely  as  the  spark  of  fire  that 
would  cause    a    conflagration.'     This   was    repeatedly 
proven  during  the   outbreak  of  1866  in  this  city,  when 
scarcely  two   cases  occurred  in   the  same   family,  so 
promptly   were  remedies   employed.     An   outbreak  of 
cholera  among  the  institutions  on  Blackwell's  Island  was 
in  the  same  manner  at  once,  and  absolutely,  suppressed 
by  attacking  the  germs,  and  guarding  the  inmates  against 
the  ingestion  of  choleraic  matters.     It  will  be  readily 
understood  that  preventive  measures  based  on  these  prin- 
ciples wholly  discard  non-intercourse,  whether  enforced 
by  cordon  sanitaire  or  shot-gun  quarantine.     On   the 
contrary,  no  other  obstruction  is  offered  to  travel  and 
traffic  than  what  may  be  necessary  to  find  and  destroy 
the  germs  in  transit. 

Again  we  repeat  that  in  the  light  of  the  above  facts 
our  quarantine  system,  and  our  quarantines  at  their  best, 
will  prove  at  present,  as  in  the  past,  no  effectual  barrier 
against  the  introduction  of  cholera  into  this  country. 
They  are  a  delusion  which  serves  a  good  purpose  in 
quieting  the  apprehensions  and  fears  of  the  public  mind, 
but  should  no  longer  deceive  the  health  authorities  of 
this  country,  and  especially  of  the  great  seaboard  cities. 
Not  a  moment  should  be  lost  in  the  most  thorough  sani- 
tation of  these  cities,  and  a  vigilant  supervision  should 
be  given  to  all  forms  of  diarrhoeal  affections.     We  do  not 
assume  the  rdle  of  alarmists,  but  would  in  all  seriousness 
warn  our  health  authorities  that  cholera    in    a    seaport 
town  of  Europe  always  did,  and  now  does,  indicate  that 
it  is  at  our  own  doors. 

The  only  system  of  preventive  measures  against  epi- 
demics of  foreign  origin  which  can  ever  adequately  ac- 
complish the  purpose  was  partially  organized  by  the 
National  Board  of  Health.  Had  its  powers  been  equal 
to  the  task  we  should  now  have  a  service  which  would 
be  an  impregnable  defence  against  the  invasion  ot 
cholera.  That  Board  inaugurated  the  following  scheme, 
viz.:  I.  The  co-operation  of  commercial  nations  in 
notification  of  the  existence  of  pestilential  diseases,  in 
uniform  and  well-matured  measures  of  defence  and  pro- 
tection. 2.  Sanitary  inspection  of  every  vessel  at  the 
port  of  departure,  with  power  to  detain  and  care  for  the 
sick,  to  secure  absolute  cleanliness  of  the  ship,  and  to 
thoroughly  supervise  the  cargo.  3.  A  sanitary  service  at 
sea  which  should  isolate  every  form  of  contagious  dis- 
ease, destroy  the  first  evidence  of  contagion,  and  pre- 


July  12, 1884.3 


THE  MEDICAL  RECORD. 


41 


serve  the  vessel,  passengers,  and  cargo,  in   the  best 
saaitaiy  condition.    4.  A  series  of  insular  refuge  stations 
to  irhich  every  infected  vessel  must  resort  before  at- 
tempdog  to  enter  a  port ;  this  station  was  to  be  fully 
equipped  with  every  appliance  which  science  and  ex- 
penence  could  suggest  for  the  cure  of  the  sick,  the 
cleansing  of  the  ship,  and  purification  of  the  cargo.    5. 
Local  quarantines  with  every  provision  for  the  most  exact 
expert  examination  of  passengers,  cargo,  and  vessel,  as 
to  the  presence  of  the  germs  of  disease.     Such  a  service 
is  practicable,  and  when  fully  perfected  and  put  in  opera- 
tion will   bring  to  a  summary  termination  the  roving 
pestilences  which  now  infest  the  great  lines  of  travel  and 
commerce.    But  until  this  reform  is  accomplished  local 
sanitary  authorities  must  rely  upon  works  of  cleansing 
to  remove  every  condition  favorable  for  the  reception 
and  propagation  of  the  epidemic,  and  by  vigilant  in- 
qiiiiy  and  inspection  discover  the  first  evidences  of  the 
presence  of  the  disease,  and  destroy  every  vestige  of  con- 
tagion. 

INFANTICIDE  IN  THIS  CITY. 
Murder  has  always  been  looked  on  as  the  most  heinous 
of  Climes,  and  only  to  be  expiated  by  the.  life  of  the 
mmderer.  This  view,  of  course,  is  the  one  taken  from 
the  spirit  and  letter  of  the  law.  Although  at  times  the 
object  of  the  law  is  defeated  through  a  variety  of  causes, 
die  justice  of  capital  punishment  is  seldom  disputed.  It 
happens  at  intervals  that  a  very  carnival  of  murder  seems 
to  pervade  certain  communities,  and  then  the  sense  of 
outraged  justice  asserts  itself,  and  the  people  demand 
the  rigid  enforcement  of  the  provisions  for  its  punish- 
ment In  New  York  City  crimes  have  been  committed, 
oijsterious  and  horrible,  like  the  Nathan  murder,  that 
have  been  for  weeks  and  months  the  wonder  of  sensation 
lovers  and  the  fear  of  the  timid.  The  newspapers  devote 
cohimn  after  column  depicting  every  minute  detail  of 
such  tragedies  as  the  one  mentioned,  and  yet  of  another 
fonn  of  murder,  more  revolting  if  possible,  there  is  seldom 
any  mention  made,  or  if  there  is  it  takes  the  shape  of  a 
three  or  four  line  item. 

Suppose  in  the  space  of  four  months  and  a  half  the 
police  had  picked  up,  in  various  parts  of  Manhattan 
Ishnd,the  bodies  of  forty^five  unknown  men  and  women 
ifao  had  met  death  by  violence,  starvation,  or  exposure 
at  te  hands  of  parties  unknown  ?  Would  not  the  public 
heart  almost  congeal  with  horror  to  think  of  the  awful 
satonialJa  of  homicide  being  carried  on  in  the  city? 
li^odd  not  the  citizens  of  New  York  demand,  in  tones 
aotto  be  misunderstood,  that  every  e£fort  should  be  used 
to  bring  the  murderers  to  justice?  There  has  not  been 
m  the  time  mentioned  that  number  of  adult  bodies  found, 
bat  there  has  been  of  children  ranging  in  age  from  a  few 
luuis  up  to  two  months.  In  February  there  were  three 
imnd,  in  March  seven — three  on  one  day,  the  28  th ;  in 
April  dght ;  in  May  twenijhone^  and  in  June  up  to  the 
20th  of  the  month,  six.  To  give  some  idea  of  the  extent 
of  tenitory  covered  by  these  figures,  it  is  enough  to  say 
that  eighteen  police  precincts.  Central  and  Riverside 
Parks,  are  represented.  These  statistics  are  from  the 
Coroners'  records  and  are  presumed  to  be  correct,  and 
do  not  indode  any  cases  of  foeticide ;  neither  are  any 
Bidnded  of  which  there  is  the  least  knowledge  in  regard 


to  either  parent  or  of  the  child  previous  to  the  finding  of 
the  body.  These  forty-five  are  absolutely  unknown,  and 
almost  certainly  the  victims  of  infanticide.  The  Coroners 
have  held  inquests  in  all  the  cases  and  found  that  death 
has  resulted  from  many  causes,  but  beyond  drawing  the 
fees  accruing  it  cannot  be  said  that  they  have  done  any- 
thing in  the  premises.  Indeed,  it  is  hard  to  believe  that 
they  do  not  consider  the  frequency  of  this  fearful  crime 
in  the  nature  of  a  special  dispensation  rather  than  a  sad 
commentary  on  the  decaying  morals  of  a  civilized  peo- 
ple. 

The  police,  too,  apparently  regard  infanticide  as  a 
necessary  evil,  and  make  no  attempts  to  discover  the 
perpetrators ;  or  if  they  do  make  such  efforts,  they  are 
only  perfunctory  and  are  given  up  almost  as  soon  as 
started.  They  have  a  most  peculiar  method  of  reasoning 
in  explaining  their  luke-warmness  in  ferreting  out  thb 
species  of  murder.  Their  argument  is,  in  effect,  that  the 
ones  who  commit  the  crime  are  so  cautious  and  circum- 
spect in  disposing  of  the  evidence  in  another  part  of  the  • 
city  from  that  in  which  the  crime  was  committed,  that  it 
would  be  useless  to  attempt  to  discover  the  author. 
Strong  logic,  truly  !  The  crime  of  murder  can  be  en- 
gaged in  with  impunity  if  the  murderer  will  only  act  with 
discretion  I  The  reasoning  is  too  diaphanous,  however. 
There  is  in  most  of  these  cases  a  strong  thread  of  evi- 
dence to  begin  with,  which,  in  the  hands  of  one  who 
cared  to  use  it,  could  be  turned  into  a  mighty  cable,  or  at 
least  into  a  hempen  rope  strong  enough  to  sustain  in 
mid-air  the  fiend  or  devil  cruel  enough  to  destroy  a  de- 
fenceless child.  The  claim  that  evidence  is  hard  to  ob« 
tain  might  be  listened  to,  were  the  facts  different  and  the 
finding  of  a  ghild's  body  a  rarity  ;  but  it  seems  supremely 
silly  to  set  up  such  an  excuse  when  the  instances  are  so 
widely  scattered  throughout  the  city  and  of  such  alarm- 
ing and  amazing  recurrence.  Some  parts  of  the  city 
seem  to  be  favorite  and  selected  repositories  for  mur- 
dered children ;  one  of  these  delightful  spots  is -that  part 
of  the  Eighteenth  Precinct  situate  between  Twenty-third 
and  Twenty-fifth  Streets  and  First  and  Second  Avenues. 
This  vicinity  has  been  selected,  no  doubt,  on  account  of 
its  propinquity  to  the  Morgue,  and  such  little  incidents 
s^rve  to  show  the  tender  consideration  of  these  pleasant 
people  to  whom  abortion  is  a  recreation  and  child-murder 
a  pastime. 

On  the  night  of  May  ist  a  party  of  boys  found  the 
body  of  a  child  in  a  marble-yard  on  Twenty-third  Street, 
near  First  Avenue.  An  officer  of  the  Eighteenth  Precinct 
brought  the  body  to  the  Morgue.  It  was  about  five 
weeks  old,  and  about  its  neck  and  face  showed  signs  of 
death  from  either  suffocation  or  strangulation.  It  was 
well  clothed  and  had  been  placed  in  a  coarse  bag  with  a 
paving-stone  weighing  ten  or  twelve  pounds.  Manifestly 
the  intention  of  the  party  leaving  the  body  in  the  marble- 
yard  was  to  await  an  opportunity  to  drop  it  in  the  East 
River.  In  answer  to  an  inquiry  made  by  a  reporter  the 
sergeant  at  the  desk  in  the  police-station  said  that  the 
case  did  not  amount  to  anything,  and  even  if  it  was  in- 
fanticide, it  would  be  impossible  to  obtain  any  clue.  The 
following  night  another  body  was  found  a  block  distant 
from  where  the  first  was.  Two  nights  after  a  third  dead 
child  turned  up  within  a  stone's  throw  of  the  police  sta- 
tion.    Three  cases  in  four  days!    and  yet  there  was 


42 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


nothing  to  work  on  !  It  is  safe  to  say  that  any  reporter 
who  had  taken  a  case  with  as  good  points  as  these  would 
never  hold  up  his  head  again  had  he  not  worked  them  to 
a  successful  conclusion.  Further  than  this,  leaving  out 
of  the  question  the  evidence  furnished  by  the  circum- 
stances attending  the  finding  of  each  body,  there  is  the 
undeniable  fact  that  no  child  is  born  without  some  one 
knowing  of  the  birth  beside  the  mother,  and  it  is  rank 
foolishness  to  assert  that  the  child  can  disappear  and  only 
one  person  be  acquainted  with  the  circumstance. 

But  the  police  do  injustice  to  their  detective  abilities. 
The  real  reason  they  make  no  effort  to  unearth  the  mur- 
derers of  children  is  not  the  lack  of  evidence  but  the  lack 
of  inducement.  These  poor  murdered  children  never  had 
the  right  to  exist,  and  if  they  are  made  away  with  no  one 
grieves  or  pines.  The  unhappy  mother  is  rid  of  a  burden, 
the  father  of  a  stumbling-block,  and  the  world  of  a  bas- 
tard. The  child  itself  is  better  off  too,  is  the  argument 
of  the  practical.  All  of  which  may  be  true — but  shame 
*  on  a  social  system  which  makes  infanticide  possible  by 
teaching  that  it  is  a  crime  for  a  child  to  be  born  ! 

It  is  undoubtedly  correct  to  say  that  nine-tenths  of  the 
people  who  ever  give  a  thought  to  the  subject  feel  a 
throb  of  pity  for  the  so-called  unfortunate  mother  who 
destroys  her  child.  These  mistaken  soft-hearted  persons 
seldom  stop  to  consider  that  in  many  cases  the  mother 
does  not  do  the  job  herself,  but  contracts  for  it  through 
the  agency  of  a  baby-farm.  Probably  many  of  these 
dead  children  are  the  offspring  of  women  living  a  dis- 
reputable life,  who  through  negligence  or  ignorance  have 
allowed  themselves  to  become  mothers.  Pity  is  wasted 
here  at  least.  Even  if  the  mother  is  a  young  girl  who 
has  listened  to  the  seducer,  no  excuse  can  be  invented 
to  cover  up  her  fault  when  she  becomes  a  murderess. 
Leaving  speculations  and  arguments  aside,  one  truth 
stands  out  in  bold  and  horrid  relief,  and  that  is  that  foeti- 
cide and  infanticide  are  looked  upon  to-day  with  a  feel- 
ing nearly  akin  to  indifference.  When  a  Christian  people 
have  reached  that  point  where  they  are  not  susceptible 
to  such  insidious  attacks  on  the  very  basis  of  all  morality, 
it  is  time  to  sound  an  alarm  and  insist  on  the  enforce- 
ment of  the  statute  law  relating  to  murder,  whether  the 
victim  be  the  offspring  of  a  person  of  mark  or  only  the 
unfortunate  illegitimate  child  of  a  common  woman. 


TEMPERANCE  PHYSIOLOGY  IN  THE  PUBLIC  SCHOOLS. 
Publishers,  in  this  and  other  cities,  of  text-books  for 
schools  are  brought  to  face  a  curious  result  of  the 
present  energetic  work  of  the  temperance  agitators. 
Writers  or  editors  of  school-books  on  anatomy,  physiol- 
ogy, and  hygiene  are  compelled  to  pay  especial  atten- 
tion to  the  poisonous  and  demoralizing  effects  of  alcohol 
and  tobacco.  In  order  to  get  a  physiology  accepted,  the 
essential  requisite  is  not  that  it  be  a  good  text-book,  but 
that  a  disproportionate  space  be  given  to  these  subjects, 
and  that  statements  be  made  which  are  hardly  borne  out 
by  facts  or  in  accordance  with  the  conclusions  of  science. 
It  may  be  seriously  questioned  whether  it  is  wise,  after 
all,  thus  to  inject  temperance  tracts  into  the  body  of  a 
science  text-book.  In  the  long  run  it  pays  best  to  tell 
and  teach  the  exact  truth.  And  we  are  quite  sure  the 
exact  truths  regarding  alcohol   and  tobacco  are  sufH- 


ciently  terrible  to  impress  duly  the  child.  To  say,  as  some 
text-books  seem  to  do,  that  alcohol  is  a  poison  and  a 
deadly  poison,  that  it  causes  catarrhs,  sclerosis,  dropsy, 
crime,  insanity,  and  shortened  lives,  and  that  moderate 
indulgence  is  an  impossibility,  is  to  present  only  one  side 
of  the  picture.  When  the  young  student  grows  up  and 
finds  whole  nations  indulging  in  alcohol  habitually,  with 
no  excess  of  drunkenness,  and  when  he  learns  other  feat- 
ures of  the  reverse  of  the  picture,  the  results  of  his  one- 
sided instruction  may  easily  prove  to  be  bad.  Medical 
men  are  agreed  that  alcohol  is  a  poison  to  youth  and  to 
those  of  hereditary  taint,  that  it  is  dangerous  in  manhood, 
but  is  helpful  in  declining  age.  They  also  see  that  mod- 
erate drinking  with  the  meals  is  a  possible  and  often  use- 
ful practice. 

Is  not  this  enough  to  teach,  without  making  our  school 
text-books  the  organs  for  an  intemperate  and  dangerous 
fanaticism  ? 

ANiESTHETICS  IN  ST.  PETERSBURG. 

It  is  always  interesting  to  learn  of  the  practical  methods 
employed  by  physicians  and  surgeons  who  live  in  dis- 
tant countries  and  under  different  conditions  from  our 
own.  At  a:  meeting  of  the  society  of  St.  Petersburg 
physicians  in  January  last,  a  large  number  of  members 
contributed  their  experience  in  the  use  of  anaesthetics, 
and  we  believe  that  an  account  of  the  opinions  expressed 
will  be  instructive.  It  will  be  seen  at  once  that  the  St. 
Petersburg  profession  is  still  in  the  chloroform  era  of 
anaesthesia.  This  is  generally  the  case  in  those  parts  of 
Europe  in  which  the  life  of  the  lower  classes  is  esteemed 
of  rather  small  moment 

Dr.  Schmitz  began  the  discussion  by  saying  that  in  the 
Children's  Hospital  of  the  Princess  Oldenburg  a  doubly 
rectified  chloroform  was  used,  and  that  even  in  operations 
lasting  an  hour  and  a  half  no  bad  effects  had  been  ob- 
served. 

Dr.  Wulff  said  that  at  the  Obuchow  Hospital  com- 
mercial chloroform  was  employed.  In  the  case  of  alco- 
holic patients  it  was  customary  to  give  a  preliminary 
hypodermic  injection  of  morphine  to  facilitate  the  anaes- 
thesia. Severe  collapse  in  the  use  of  chloroform  was  not 
often  observed.  A  few  cases  of  death  had  occurred,  but 
it  was  doubtful  if  the  chloroform  was  the  cause. 

Drs.  Hirsch  and  Petersen  related  cases  of  obstinate 
resistance  to  anaesthesia.  Dr.  Hirsch' s  case,  a  very 
feeble  man,  failed  to  be  affected  by  an  ounce  and  a  half 
of  chloroform. 

Drs.  Moritz  and  Schmitz  related  histories  of  cases  of 
pronounced  hea:^  disease  in  which  chloroform  was  given 
without  harm. 

Dr.  Hirsch  thought  that]  in  cases  of  heart  disease  the 
chloroform  might  kill  when  given  a  second  time  if  it  did 
not  the  first,  and  instanced  an  illustrative  case  in  his 
own  practice. 

Drs.  Moritz,  Petersen,  and  Hintze  all  thought  that 
some  of  the  cases  of  sudden  death  after  admimstration  of 
chloroform  were  the  results  of  psychical  influence.  Sev- 
eral cases  were  referred  to  in  which  death  suddenly  oc- 
curred on  the  application  of  the  knife,  although  no 
antiseptic  had  been  given. 

Dr.  Hoist  thought  that  preliminary  morphine  injec- 
tions did  not  act  well.    They  caused  an  unquiet  narcosis. 


July  12,  1884-] 


THE   MEDICAL  RECORD. 


43 


Dr.  Monastyrski  thought  that  these  injections  made 
the  stage  of  excitement  shorter^  but  that  in  the  stage  of 
narcosis  there  was  more  danger  of  asphyxia.  He  had 
bad  much  better  results  with  the  doubly  purified  chloro- 
form than  with  the  commercial  article.  He  had  given 
cbloroform  to  patients  with  heart  disease  several  times 
with  no  bad  results. 

In  reply  to  a  question  as  to  the  age  at  which  it  is  safe 
to  give  chloroform  to  a  child,  Dr.  Wulflf  said  that  he  had 
given  it  twelve  times  in  one  day  to  a  child  under  two 
weeks  of  age.  Dr.  Schmitz  had  administered  chloroform 
to  a  baby  twelve  days  old,  and  performed  an  amputation 
under  its  influence. 

Dr.  Magawly  had  used  chloroform  in  hospital  and 
private  practice  for  many  years.  He  had  only  met  with 
tiro  deaths,  both  occurring  in  weak  and  emaciated  pa- 
tients.   Autopsy  in  one  case  revealed  a  fatty  heart. 


NEW  MET!HODS  OF  TREATING  EPILEPSY. 

A  WRITER  in  the  JBer liner  Klinischer  Wochenschrift  has 
nsed  perosmic  acid  in  the  treatment  of  epilepsy,  giving  it 
in  M  form  in  doses  of  .002  milligr.  He  has  had  but 
little  success,  a  few  cases  only  having  notably  improved. 
He,  however,  thinks  the  remedy  worthy  of  further  trial. 
Boumeville  and  £ricon  have  recently  reported  the  re- 
sults of  their  experience  in  treating  epilepsy  with  sclero- 
tinic  acid.  They  gave  it  in  daily  doses  of  10  ctgr. 
gradually  increased  to  25.  Among  twelve  patients  thus 
treated,  amelioration  was  obtained  in  only  five.  The 
drug  is  a  failure  as  an  anti-epileptic. 

Professor  William  Pepper  has  delivered  several  clini- 
cal lectures  upon  the  treatment  of  epilepsy  in  children. 
He  calls  special  attention  to  the  value  of  careful  regula- 
tion of  diet,  of  removing  all  ^soturces  of  irritation,  and 
of  securing  rest,  including  plenty  of  sleep. 

In  a  series  of  experiments  on  chronic  epileptics.  Pro- 
fessor Henry  C.  Wood  found  that  bromide  of  hydrogen 
(hydrobromic  acid)  decreased  the  number  of  fits  more 
dian  the  other  bromides.  He  gave  it  in  doses  of  §  >  to 
\  iij.  daily. 

Dr.  S.  Hughes  Bennett,  while  offering  no  new  remedy 
for  epilepsy,  has  recently  published  statistics  which  show, 
as  he  thinks,  that  under  bromides  attacks  are  stopped  in 
12.1  per  cent,  of  cases,  are  lessened  in  83.3  per  cent, 
ffldare  increased  in  2.3  per  cent.  He  also  believes  his 
operience  to  show  that  the  continued  use  of  the  bromides 
exercises  no  deleterious  mental  or  physical  effect  except 
in  a  small  proportion  of  cases.  He  thinks  that  epileptics 
can  take  bromides  better  than  other  persons,  and  that 
in  course  of  time  the  eruptions  and  the  depression  dis- 
appear. 

The  experience  of  Kunze,  who  claims  to  have  cured 
nine  epileptics  out  of  thirty-five  with  curare,  has  not  been 
repeated  by  others.  Curare  has  almost  uniformly  failed 
to  effect  any  real  benefit  in  epilepsy. 

Ball,  in  addition  to  the  use  of  bromides,  belladonna, 
and  zinc,  advises  the  use  of  leeches  to  the  mastoid  pro- 
cess, and  cathartics,  in  order  to  correct  cerebral  conges- 
tion. 

Little  has  ever  been  done  for  epileptics  by  the  use  of 
dectridty.      The  recent  very  favorable  expression  as 


to  its  value  by  Erb  may,  however,  lead  to  further  and 
more  careful  trials. 

f  The  experiments  of  Boumeville  with^the  bromides  of 
gold,  camphor,  arsenic,  etc,  show  that  not  so  good  re- 
sults can  be  obtained  by  these  preparations  as  by  the 
ordinary  bromide  compounds. 

Continued  contributions  to  the  therapeutics  of  epilepsy 
only  show  that  almost  any  new  remedy  can  produce  some 
temporary  amelioration  of  the  disease.  But  nothing  at 
all  approaching  in  value  the  bromide  compounds  as  anti- 
epileptics  has  yet  been  discovered. 


HIGH  FEES  IN  DENTISTRY. 
The  astonishing  statement  appeared  a  few  days  ago  in 
the  daily  press  that  a  dentist  of  this  city  had  charged  a 
fee  of  seven  thousand  dollars  for  four  days'  work  in  den- 
tistry. It  appears  that  the  patients  were  three  wealthy 
ladies  of  one  family,  and  that  the  operators  were  father 
and  three  sons.  Time  consumed  four  days,  with  some 
extra  work  after  hours.  Value  of  time-work  $50  per 
hour  for  each  gentleman.  So  much  can  be  learned 
from  the  reports  referred  to.  The  gentleman,  a  foreigner, 
to  whom  the  bill  has  been  sent,  thinks  there  must  be 
some  mistake,  and  asks  for  explanations.  Being  assured 
tojthe  contrary  by  the  operators,  he  is  more  astonished 
than  ever,  and  refuses  to  pay  the  amount. 

On  general  principles  skilled  labor  deserves  to  bejwell 
rewarded,  but  even  that  has  a  standard  withinfeasy 
range  of  ordinary,imagination.  When  applied  to][den- 
tistryjit  is  [^hard^  to  associatej  teeth-pulling,  teeth-filling, 
and  plate-making  with  such  extraordinary  or  special 
skill  as  would  place  the  value  of  services  so  dispropor- 
tionately high  as  compared  with  similar  work  in  any 
other  mechanical  grade.  It  is  safe  to  say  that  no  diffi- 
cult capital  operation  in  surgery,  upon  the  skilful  per- 
formance of  which  would  depend  the  actual  life  of  a  pa- 
tient, could  command  such  a  fee ;  nor,  indeed,  would 
any  approach  to  such  a  sum  be  charged  by  any  consci- 
entious or  reputable  surgeon.  And  yet  the  dentist, 
whose  responsibilities  are  nothing,  and  whose  skill  at 
best  in  his  ordinary  vocation  of  teeth>^lugging  is  equal 
to  that  of  a  first-class  mechanic,  can  cNarge  a  fee  which 
would  put  to  blush  the  most  ambiticvs  professional 
money-getter,  and  astonish  the  capabilities  of  a  million- 
aire. 


THE  HURST  PERFORMANCE. 
The  Georgia  Wonder,  Miss  Lulu  Hurst,  has  been  ex- 
hibiting her  alleged  wonderful  powers  in  this  city  during 
the  past  week.  We  may  say  at  once  that  she  failed  to 
satisfy  the  intelh'gent  and  critical  among  her  audiences 
that  she  possessed  any  occult  force  whatever.  The  re- 
marks which  we  made  concerning  her  in  a  previous  edi- 
torial were  perfectly  justified  by  a  careful  personal  exam- 
ination of  her  exhibitions.  The  "  new  force"  acts  only 
through  the  muscles  of  Miss  Hurst  and  those  experi- 
mented upon.  It  is,  in  fine,  muscular  force,  and  that  is 
all.  Miss  Hurst  is  a  strong,  large-framed  girl,  and  has 
the  power  of  very  rapidly  contracting  her  muscles.  A 
man  takes  hold  of  a  cane  with  two  hands  and  is  told  to 
hold  it  still  if  he  can.  He  immediately  throws  his 
muscles  into  a  state  of  extreme  tension;  Miss  Hurst 


44 


THE   MEDICAL  RECORD. 


[July  12,  1884- 


tlien  lays  her  big  hands  on  the  cane,  with  the  thumbs 
underneath,  we  are  told.  By  very  slight  but  rapid  mus- 
cular movements  the  cane  is  twitched  around.  The 
more  the  man  resists,  the  more  tense  his  muscles,  and 
the  more  easily  the  cane  is  pushed  about.  Soon  the  man 
becomes  excited ;  he  thinks  he  is  wrestling  with  a  force, 
and  performs  various  ludicrous  gyrations.  Miss  Hurst 
ingeniously  makes  him  labor  and  perspire  over  nothing. 
This  is  the  sura  and  substance  of  all  the  experiments. 
No  test  upon  an  inanimate  object  shows  anything  at  all. 
In  keeping  a  chair  from  the  floor,  she  holds  'it  in  a  pe- 
culiar way,  and  apparently  exerts  her  own  not  inconsid- 
erable strength. 

If  Miss  Hurst,  as  is  possible,  is  not  consciously  de- 
ceiving, then  it  would  seem  as  if  the  contact  of  her 
hands  with  umbrellas,  chairs,  and  billiard  cues  produced 
a  kind  of  artificial  chorea.  The  phenomena  she  exhibits 
and  calls  out,  are,  at  any  rate,  interesting  perversions  of 
the  ps3xho-motor  sphere. 

They  are  still  more  interesting  as  illustrating  the  cre- 
dulity and  the  utter  incapacity  for  scientific  examination 
of  such  performances  which  have  existed  among  most 
of  her  audiences.  We  understand,  however,  that  the 
true  nature  of  her  *' force"  has  been  exposed  since  her 
arrival  in  this  city. 

g^ettra  of  tlue  WSicf^h. 


Death  of  a  Doctor  from  Chloroform. — Dr.  Mac- 
Rae,  of  Scotland,  wa.s  suffering  from  a  tumor  at  the  nape 
of  the  neck,  for  the  removal  of  which  he  went  to  Edin- 
burgh, and  placed  himself  under  the  care  of  Professor 
Annandale.  While  the  chloroform  was  being  adminis- 
tered prior  to  the  necessary  operation.  Dr.  MacRae,  who 
was  in  the  prime  of  life,  suddenly  died. 

Memorandum  for  the  Prevention  of  Cholera. — 
The  State  Board  of  Health  has  issued  a  memorandum 
regarding  the  measures  to  be  taken  to  prevent  the  intro- 
duction and  spread  of  cholera  in  this  coimtry.  The 
Board  consider  it  probable  from  past  experience  that 
cholera  will  reach  this  country,  and  they  recommend  the 
most  careful  disinfection  and  cleansing  of  our  cities  and 
towns. 

Progress  of  the  Cholera. — The  deaths  from  chol- 
era at  Toulon  and  Marseilles  have  been  slowly  increas- 
ing in  number  daily  from  July  ist  to  8th,  as  follows : 
July  ist,  Toulon,  6 ;  Marseilles,  3.  July  2d,  Toulon,  5  ; 
Marseilles,  4.  July  3d,  Toulon,  13';  Marseilles,  5.  July 
4th,  Toulon,  4.  July  5th,  Toulon,  7;  Marseilles,  12. 
July  6th,  Toulon,  4;  Marseilles,  15.  July  7th,  Toulon, 
9  ;  Marseilles,  16.  July  8th,  Toulon,  10 ;  Marseilles,  14 ; 
Nice,  I  (?).  The  total  number  of  deaths  from  cholera  at 
Toulon  since  the  beginning  of  the  epidemic  is  154,  The 
number  of  cases  in  the  hospitals  at  Toulon  has  been  be- 
tween 115  and  150.  Despite  the  number  of  cases  at 
Marseilles  the  death-rate  of  the  city  is  low,  and  it  is  be- 
lieved that  a  great  deal  of  needless  alarm  exists.  Dr. 
Koch  has  arrived  at  Toulon,  and  has  found  the  bacillus 
of  cholera  in  the  intestines  of  those  who  have  died  from 
the  disease.  He  pronounces  it  Asiatic  cholera,  there- 
fore. He  is  reported  to  have  stated  that  it  would  spread 
to  Germany ;  also  that  the  germs  of  the  disease  were 


taken  into  the  system  in  food  and  drink,  not  by  inhala- 
tion. While  the  Spanish,  Italian,  and  Austrian  Govern- 
ments have  instituted  quarantine  against  vessels  from 
French  ports,  England  refuses  to  adopt  anything  but  her 
inspection  system.  A  vessel  from  Marseilles  with  two 
cases  of  cholera  on  board  is  said  to  have  been  intercepted 
in  the  Channel.  All  passengers  and  baggage  arriving  at 
Paris  from  infected  districts  have  now  to  be  disinfected. 

The  Colorado  State  Medical  Society  met  at 
Denver  on  June  19th,  20th  and  21st.  Dr.  Whitehead, 
President,  in  the  Chair.  The  following  officers  were 
elected  for  the  ensuing  year  :  President — Dr.  Hawse,  of 
Greeley ;  Vice-Presidents — Drs.  Soly,  Rogers,  and  Ear- 
hart  ;  Recording  Secretary — Dr.  S.  A.  Fisk. 

The  Investigation  of  Lulu  Hurst. — ^We  have 
received  a  number  of  letters  from  Southern  medical  men 
protesting  against  our  judgment  of  Miss  Hurst's  per- 
formances. We  venture  to  answer  them  all  here  by 
publishing  a  letter  written  in  answer  to  one  of  them  by 
a  gentleman  who  investigated  the  matter  at  our  request : 
"  Dear  Doctor :  Having  been  asked  to  investigate  the 
Hurst  phenomenon,  I  went  and  saw  her  last  night  In 
common  with  the  medical  gentlemen  with  me,  I  thought 
she  utterly  failed  to  demonstrate  the  possession  of  an/ 
peculiar  powers;  the  phenomena  could  all  be  ex- 
plained, and  easily,  by  assuming  the  existence  of  uncon- 
scious convulsive  movements  and  by  the  peculiar  mus- 
cular rigidity  and  expectant  state  into  which  those 
experimented  upon  got  themselves.  While  perfectly 
willing  to  be  convinced,  we  saw  nothing  to  justify  us  in 
assuming  a  new  force,  but  only  a  curious  disturbance  of 
the  voluntary  motor  system,  and  an  interesting  illustra« 
tion  of  what  may  be  done  with  persons  in  a  state  of  ex« 
pectancy  and  great  muscular  tension.  Some  of  her 
experiments  were  subsequently  repeated  among  our- 
selves. Miss  Hurst  does  indeed  cause  dead  matter  to 
move,  but  no  more  than  any  large  and  muscular  girl 
could  make  it." 

Disinfection  of  Rags  from  Egypt. — The  following 
are -methods  of  disinfecting  rags  which  are  considered 
satisfactory  by  the  Treasury  Department :  i.  Boiling  in 
water  for  two  hours  under  a  pressure  of  fifty  pounds  per 
square  inch.  2.  Boiling  in  water  for  four  hours  without 
pressure.  3.  Subjection  to  the  action  of  confined  sul- 
phurous-acid gas  for  six  hours,  burning  one  and  a  half  to 
two  pounds  of  roll  brimstone  in  each  1,000  cubic  feet  of 
space,  with  the  rags  well  scattered  upon  racks. 

Local  Health  Officers  and  Inspectors  of  Cus- 
toms.— The  Treasury  Department  has  decided  that  State 
Health  authorities  cannot  prevent  United  States  Inspec- 
tors of  Customs  from  landing  at  quarantine  stations  and 
pursuing  their  duties  there,  if  necessary.  The  question 
came  up  at  Charleston,  S.  C. 

Experiments  with  a  Decapitated  Human  Head. — 
M.  I^abarde  has  been  making  some  truly  ghastly  experi- 
ments with  the  head  of  Campi,  the  murderer,  who  was 
recently  executed  in  Paris,  and  in  the  Revue  Scientifique 
he  publishes  an  account  of  them.  By  means  of  a  tube 
he  connected  the  carotid  artery  of  the  head  with  the 
corresponding  artery  of  a  living  dog,  and  the  head  being 
placed  upright  on  a  table,  the  stop  placed  on  the  dog 


July  12,  i884*] 


THE  MEDICAL  RECORD. 


45 


iras  removed.  As  the  blood  was  carried  into  the  head 
the  livid  hue  of  the  face  disappeared  and  color  returned, 
the  forehead  and  cheeks  being  suffused  and  the  eyelids 
moving.  Some  time  had  elapsed  since  Campi's  death, 
and  M.  Labarde  regrets  that  such  experiments  cannot 
tske  place  immediately  after  execution,  as  the  physiolo- 
gist might  thus  be  able  to  witness  a  **  grand  and  terrible 
spectacle." 

Dr.  Martin  McGovern  has  been  appointed  Police 
Surgeon,  vue  Dr.  M.  H.  Henry,  resigned. 

New  Method  of  Supporting  the  U.  S.  Marine 
Hospital  Service. — The  last  Congress  passed  the  fol- 
lowing law :  "  That  sections  forty-five  hundred  and 
eighty-five,  forty-five  hundred  and  eighty-six,  and  forty- 
five  hundred  and  eighty-seven  of  the  Revised  Statutes, 
and  all  other  acts  and  parts  of  acts  providing  for  the  as- 
sessment and  collection  of  a  hospital  tax  for  seam^,  are 
hereby  repealed,  and  the  expense  of  maintaining  the 
Marine  Hospital  Service  shall  hereafter  be  borne  by  the 
United  States  out  of  the  receipts  for  duties  on  tonnage 
provided  for  by  this  act ;  and  so  much  thereof  as  may  be 
necessary  is  hereby  appropriated  for  that  purpose." 
The  sailor  is,  therefore,  no  longer  taxed  forty  cents  a 
month,  and  the  marine  hospital  service  is  supported  by 
the  owners  of  vessels,  instead  of  by  their  employees. 
The  question  may  now  be  raised,  whether  employers  can 
constitutionally  be  taxed  for  the  support  of  their  employ- 
ees when  sick. 

Gifts  to  Hospitals. — ^The  sum  of  two  million  francs 
was  bequeathed  by  the  late  Baroness  Alquier  for  the 
erection  of  a  new  hospital  in  Paris.  The  London  Hos- 
pital has  just  received  $50,000  from  Baroness  Rothschild. 

Membership  in  the  American  Medical  Associa- 
tion.— ^At  the  meeting  of  the  American  Medical  Asso- 
ciation, held  at  Washington  in  May  last,  an  amendment 
to  Emulation  II.  was  adopted,  which  provides  that 
*'Membeiship  in  the  Association  shall  be  obtainable  by 
any  noember  of  a  State  or  County  Medical  Society  recog- 
nized by  the  Association,  upon  application,  endorsed  by 
the  President  and  Secretary  of  said  Society ;  and  shall  be 
retained  so  long  as  he  shall  remain  in  good  standing  in 
his  local  Society,  and  shall  pay  his  annual  dues  to  the 
Association." 

A  Religious  Quack  Advertisement. — As  a  speci- 
men of  the  means  by  which  the  simple  are  induced  to 
part  with  their  money,  the  following,  says  the  Studenfs 
]wmaly  cut  from  the  advertisement  columns  of  The 
Ckrisfian  Million^  is  worthy  of  perusal:  ''The  Bitter 
Cry  for  Help. — Thousands  of  God's  creatures  are  lifting 
up  their  plaintive  voices  for  help.  Poverty  presses  hard 
upon  them,  and  renders  their  lives  a  sad  monotony, 
living  in  narrow  dwellings,  and  constantly  breathing  im- 
pure air,  they  are  physically  weak  and  altogether  unfit 
ibr  the  duties  of  life.  Sickness  and  suffering,  hunger 
and  ignorance,  are,  as  it  were,  written  on  the  very  door- 
posts of  their  dwellings.  In  higher  circles  we  find  a 
Merent  state  of  things — no  poverty,  no  badly- ventilated 
homes ;  but  many  afflictions,  nevertheless,  weigh  upon 
them,  symptoms  of  ill-health  which  their  physicians  ap- 
pear to  be  unable  to  remove — failing  sight,  deafness, 
noises  in  the  ears,  indigestion,  coughs,  and  a  variety  of 


other  complaints,  make  these  well-to-do  people  very, 
very  sad.  From  all  classes  comes  up  the  cry  for  help. 
The  man  who  has  the  power  to  help  his  brother  and  is 
unmindful  of  his  trust  is  surely  unfaithful  to  the  better 
promptings  of  his  nature.  The  noble  army  of  faithful 
workers,  ministers,  doctors,  and  sick  visitors,  deserve  our 
prayers  and  sympathy.  The  Rev.  E.  J.  Silverton,  has 
for  many  years  been  engaged  in  alleviating  the  sufferings 
of  mankind,  curing  deafness  and  removing  noises  from 
the  ears  by  means  of  his  *  Aural  Remedy,'  curing  in- 
digestion and  all  its  tortures  by  his  '  Patent  Pills,'  and 
building  up  broken-down  constitutions  by  his  '  Medical 
Energiser  and  Magic  Cough  Mixture/  and  his  'Nutrient 
Food  of  Food.'  All  these  wonderful  medicines  may  be 
ordered  of  any  Chemists,  who  will  procure  them  for  any 
sufiferer.  The  prices  are  arranged  to  meet  all  classes,  viz., 
'Patent  Pills,'  is.  ijd.,  and  2s.  9d.  per  box,"  etc.  Were 
any  ordinary  quack  to  use  the  name  of  the  Supreme  Being 
for  trade  purposes  it  would  be  considered  rank  blas- 
phemy, but,  in  the  case  of  a  '*  Reverend  "  it  is  doubtless 
accepted  by  Christian  Million  readers  as  a  guarantee  of 
good  faith. 

An  Epidemic  of  Typhoid  Fever  in  Switzerland. — 
Typhoid  fever  has  been  very  prevalent  in  Zurich,  a  city 
of  83,000  inhabitants.  The  disease  has  been  character- 
ized 'by  severe  complications.  One  of  the  causes  is 
thought  to  have  been  the  low  water  in  the  lake. 

Journalistic  Changes  and  Evolution. — The  prog- 
ress of  evolution  is  said  to  proceed  from  the  homogene- 
ous, the  simple,  and  the  undifferentiated,  to  the  hetero- 
geneous and  complex.  Exactly  the  reverse  occurred, 
nosologically  speaking,  when  the  Kansas  and  Missouri 
Valley  Medical  Index  and  the  New  Medical  Era  and 
Sanitarian  consolidated  under  the  plain  and  undifferen- 
tiated title  of  the  Medical  Index. 

Religion  and  the  American  Doctor. — Nothing 
for  a  long  time  has  so  stirred  up  the  religious  sentiments 
of  the  American  physician  as  a  resolution  introduced 
into  the  American  Medical  Association  last  May,  pro- 
posing to  dispense  with  the  opening  prayer.  Most  of  our 
contemporaries  have  made  vigorous  comments  express- 
ing approval  of  the  action  of  the  Association  in  promptly 
tabling  the  matter.  No  one  has  put  it  quite  so  vigor- 
ously, however,  as  the  energetic  editor  of  the  Texas 
Courier-Record^  who  concludes  his  criticisms  of  the  in- 
judicious introducer  as  follows : 

**  Oh,  shame,  where  is  thy  blush  ?  Oh,  cheek,  where 
is  the  limit  to  thy  flintiness?  Oh,  immaculate  gall, 
assurance,  impudence,  thy  name  is him  who  in- 
sulted that  grand  body  of  grave,  thoughtful,  earnest 
workers,  whose  very  lives  and  presence  testify  the  exist- 
ence and  providence  of  the  living  God,  and  belie  and  be- 
little your  puny  doctrine." 

It  is  no  discredit  to  the  heart  of  our  esteemed  con 
temporary  that  he  subsequently  confesses  to  having  re- 
ceived the  consolations  of  refreshment. 

Third  Congress  or  the  Italian  Surgical  So- 
ciety.— The  third  Congress  of  th^  Italian  Surgical 
Society  will  be  held  in  Turin  on  the  15th  to  the  20th  of 
September,  1884.  The  secretaries  are  Drs.  G.  Novaro 
and  G.  Berruti,  of  Turin. 


46 


THE   MEDICAL  RECORD. 


[July  12,  1884- 


The  French  Association  for  the  Advancement 
OF  Science  meets  at  filois  on  September  4  to  11,  1884. 

Vivisection  Work  in  England. — A  return  which  has 
just  been  published  showing  the  number  of  experiments 
performed  upon  living  animals  during  the  year  1883  under 
the  Vivisection  act,  is  a  somewhat  remarkable  document. 
It  appears  that  in  England  and  Scotland  44  persons  have 
held  licenses  under  the  act  during  some  part  of  that 
year,  of  whom  32  performed  experiments  and  12  per- 
formed none.  In  Ireland  8  persons  held  licenses,  of 
whom  only  4  performed  experiments.  The  total  number 
of  experiments  of  all  kinds  was  535  in  England  and  Scot- 
land, and  34  in  Ireland.  Of  these  290  were  carried  out 
under  the  restrictions  of  the  license  alone,  55  under 
special  certificates  dispensing  with  the  use  of  anaesthet- 
ics, and  122  under  certificates  dispensing  with  the  obli- 
gation to  kill  the  animal  before  recovering  from  anaes- 
thesia. Under  certificates  permitting  experiments  on 
cats,  dogs,  horses,  mules,  and  asses  there  were  102  opera- 
tions, but  it  appears  that  only  four  or  five  were  upon 
cats  or  dogs,  and  none  at  all  upon  the  other  animals 
named.  As  regards  the  290  cases  first  mentioned,  to- 
gether with  a  number  carried  out  under  certificates  pre- 
scribing anaesthetics,  the  animals  were  rendered  insensi- 
ble during  the  whole  of  the  operations,  and  were  not 
allowed  to  regain  sensibility.  Their  sufferings  were  accord- 
ingly quite  inappreciable  by  the  most  acute  sympathizer. 
The  55  experiments  without  anaesthetics  consisted  in 
simple  inoculation  or  hypodermic  injection  with  morbid 
matter  whose  operation  it  was  desired  to  discover,  and 
the  pain  inflicted  was  at  the  most  that  of  ordinary  vacci- 
nation and  its  results.  Of  the  122  experiments  in  which 
the  animals  were  allowed  to  regain  sensibility,  114  also 
consisted  principally  in  inoculation,  and  were  for  the 
most  part  connected  with  an  important  inquiry  into  the  na- 
ture of  tubercular  affections.  No  pain  was  inflicted  save  in 
some  14  or  15  instances,  and  even  in  these  it  was  trifling. 
In  the  remaining  eight  cases  anaesthetics  were  used,  and 
though  the  surgical  operations  amounted  to  more  than  a 
mere  puncture,  the  pain  would  be  only  that  usually  at- 
tending the  healing  of  a  surgical  wound.  The  experi- 
ments upon  cats  and  dogs  are  classified  under  the  heads 
already  mentioned  The  conclusion  of  the  Inspector's 
report  is  that  "  the  amount  of  direct  or  indirect  suffering 
from  the  performance  of  physiological  experiments  dur- 
ing the  past  year  was  wholly  insignificant,  and  limited  to 
about  14  or  15  animals." 

Water  and  Constipation. — Dr.  Squibb,  in  his  last 
Ephemeris^  has  a  suggestive  article  upon  constipation. 
He  thinks  that  most  constipations  are  due  to  insufficient 
water  in  the  fecal  mass.  The  individual  does  not  ingest 
enough  water  to  supply  the  blood  with  its  seventy-nine 
per  cent.,  therefore  the  blood  absorbs  it  from  the  intes- 
tinal contents.  "  Drink  water,"  is  Dr.  Squibb*s  motto.  It 
is  a  good  one ;  but  water,  as  every  one  knows,  will  not  cure 
habitual  constipation  in  a  very  large  percentage  of  cases. 

Dr.  Axel  Iversen. — ^The  name  of  the  surgeon  as- 
sociated with  rectal  etherization  should  be  written  Iver- 
sen, not  Yversen.  It  was  incorrectly  spelled  in  the  Lyon 
M^dicaly  in  which  Dr.  Molli^re's  notice  appeared,  prob- 
ably through  the  writer's  attempt  to  represent  the  Dan- 
ish pronunciation  by  the  French  spelling. 


%mizms  atid  ^flriticea. 


The  Physician's  Combined  Day-Book  and  Ledger. 
By  H.  T.  Hanks,  M.D.     New  York :  J.  H.  Vail  & 
Co.     1883. 
To  the  average  physician,  who  knows  as  little  of  book- 
keeping as  he  does  of  navigation,  one  of  the  greatest 
trials  of  his  life  is  the  keeping  his  accounts  straight,  and 
anyone  who  helps  to  simplify  and  lighten  his  labors  in 
this  direction  may  justly  be  regarded  as  a  benefactor  to 
the  profession.     And  after  a  practical  trial  of  the  system 
here  presented  we  are  disposed  to  grant  this  title  to  the 
author.     In  this  book  provision  is  made  for  the  date  and 
character  of  the  visit,  the  member  of  the  family  attended, 
special  charges,  etc.,  all  within   the  smallest   possible 
space.     The  charges  can  be  continued  from  month  to 
month  or  year  to  year  without  re-entering,  and  the  entire 
account  of  each  patient  may  be  comprehended  at  a  glance. 
The  necessity  of  a  ledger  is  done  away  with,  thus  saving 
the  gfiysician  much  time  and  avoiding  all  possibility  of 
error  in  making  the  transfer.     The  author  *'  claims  to 
have  arranged  in  this  book  the  most  exact  and  labor- 
saving  system  of  book-keeping  ever  devised  for  the  use 
of  a  physician,"  and  as  far  as  our  experience  will  permit 
us  to  judge  we  think  his  claim  is  well  founded. 
Elements  of  Pharmacy,  Materia  Medica,  and  Ther- 
apeutics.    By  William   Whitla,   M.D.  (Q.  V.  I.), 
Physician  to  the  Belfast  Royal   Hospital ;  Consulting 
Physician  to  the  Ulster  Hospital  for  Diseases  of  Wo* 
men  and  Children ;  Vice-President  of  the  Ulster  Medi- 
cal Society,  etc.     With  Lithographs  and  Woodcuts. 
Second  Edition.     London  :  Henry  Renshaw.     1884. 
This  manual,  intended  primarily  for  students,  contains  a 
vast  amount  of  practical  information  arranged  in  very 
convenient  form  for  ready  reference.     It  is  divided  into 
six  parts,  treating  of  pharmacy,  materia  medica,  thera- 
peutics, non-official  remedies,  prescription  writing,  and 
chemical  reaction,  with  some  of  the  more  important  tests. 
The  arrangement  of  the  drugs  is  in  alphabetical  order. 
There  is  an  index  of  poisons  and  their  antidotes,  and  a 
very  copious  general  index  adds  to  the  value  of  the  work 
as  a  ready-reference  manual     The  fact  that  a  large  edi- 
tion was  exhausted  within  two  years  is  a  sufficient  evi- 
dence that  the  book  has  supplied  a  want. 
Hand-Book  of  Eclampsia,  or  Notes  and  Cases  of 
Puerperal  Convulsions.     Comprising  all  the  Cases 
which  have  occurred  during  the  Present  Century  within 
a  Radius  of  Several  Miles  around  Avondale,  Chester 
Co.,  Pa.,  so  far  as  can  be  ascertained.     By  E.  Mich- 
ENER,  M.D.,  J.  H.  Stubbs,  M.D.,  B.  Thompson,  M.D., 
R.  B.  EwiNG,  M.D.,  and  S.  Stebbins,  M.D.     Phila- 
delphia :  F.  A.  Davis.     1883. 
The  authors  of  this  little  brochure  have  collected  and 
studied  forty-fpur  cases  of  puerperal  convulsions  occur- 
ring during  the  present  century  in  the  vicinity  of  Avon- 
dale,  and  have  here  presented  their  conclusions  derived 
from  this  study.     Briefly  stated,  their  belief  is  that  the 
proximate  cause  of  puerperal  eclampsia  is  hyperaemia  of 
the  brain,  and  the  treatment  based  upon  this  belief  con- 
sists in  prompt  and  plentiful  bleeding.     The  essay  will 
repay  a  careful  perusal,  even  though  the  conclusions  of 
its  authors  may  not  be  accepted  in  their  entirety. 
Female  Hygiene  and  Female  Diseases.     By  J.  K. 
Shirk,  M.D.,  Member  of  the   Lancaster  City  and 
County  Medical  Society.     Lancaster,  Pa.:  The  Lan- 
caster Publishing  Co.    1884. 
This  is  a  book  intended  for  the  laity,  and  treats  in  intel- 
ligible language  of  the  hygiene  and  diseases  of  the  female 
reproductive  organs.     It  contains  much  useful  informa- 
tion on  a  subject  of  which  women  are  often  too  ignorant, 
but  we  think  it  would  have  been  productive  of  more  un* 
mixed  good  and  would  have  served  an  equally  useful  pur- 
pose had  the  directions  concerning  the  medicinal  treat- 
ment of  disease  been  omitted. 


July  12,  1884.] 


THE  MEDICAL  RECORD. 


47 


Reports  0t  ^ocUtuB. 

NEW  YORK  PATHOLOGICAL  SOCIETY. 

Stated  Meetings  June  11,  1884. 

H.  E.  Van  Gieson,   M.D.,  Vice-Preside^,  in  the 
Chair. 

Djl  Wackerhagen  presented  specimens  as  follows ;  The 
first  was  one  of 

carcinoma  of  the  breast 

removed  from  a  German  woman  seventy-two  years  of 
age.  Twenty-five  years  ago  she  noticed  a  small  lump  in 
the  breast,  which  gradually  enlarged  but  caused  no  in- 
convenience until  two  years  ago,  when  it  became  painful. 
In  December  last  a  small  abscess  formed  below  the 
nipple,  which  continued  discharging  until  the  operation 
on  May  iSth.  During  a  few  weeks  before  the  oper- 
ation the  pain  was  at  times  very  severe,  and  she  was 
anxious  to  have  the  tumor  removed.  It  weighed  nine 
ounces,  and  consisted  of  normal  gland  structure  and  adi- 
pose tissue,  in  the  midst  of  which  was  a  mass  of  fibrous 
tissue  arranged  in  trabeculae,  which  radiated  in  all  di- 
rections, and  in  the  meshes  of  which  were  free  fat  and 
probably  some  cell  elements.  To  one  side  of  the  cen- 
tre of  this  mass  was  a  cavity  whose  walls  were  composed 
of  the  same  fibrous  material  of  a  darker  color,  and  from 
which  could  be  expressed  a  thick  greenish  juice.  This  is 
probably  a  post-mortem  change.  To  the  touch  the  speci- 
men was  fairly  firm,  and  presented  nodular  areas  of  small 
size  throughout  the  mass.  The  smaller  mass  came 
from  the  axilla.  It  weighed  about  two  ounces,  and  was 
composed  of  adipose  tissue,  lymphatic  glands,  and  nod- 
ales  the  size  of  large  chestnuts  and  composed  of  fibrous 
tissue  arranged  in  trabeculae  which  radiated  in  all  direc- 
tions, and  in  the  meshes  of  which  were  cellular  elements 
and  some  fat  To  the  touch  the  ncTdules  were  firm  and 
fairly  well  defined.  There  were  also  blood-vessels  dis- 
seminated throughout  the  mass,  but  apparently  not  in  the 
nodules,  at  least  of  appreciable  size.  The  dressings  were 
bichloride  and  iodoform,  and  were  not  removed  until  the 
eleventh  day,  when  complete  union  had  taken  place 
throughout. 

epithelioma  of  the  penis. 

The  second  specimen  was  a  portion  of  a  penis  re- 
moved from  a  gentleman  aged  sixty-four.  He  had  suf- 
fered from  irritation  of  the  glans  for  several  years,  the 
result  of  phimosis.  During  the  past  year  pain  and  itch- 
ing had  been  very  severe,  and  at  times  there  had  been 
conaderable  hemorrhage.  The  glands  in  both  groins 
were  enlarged,  but  had  decreased  greatly  in  size  since 
the  operation.  The  tendency  of  the  growth  seemed  to 
be  outward,  rather  than  down  into  the  deeper  portions  of 
the  tissue.  The  urethra  was  apparently  intact,  excepting 
at  the  meatus.  Upon  the  glans  was  seen  a  growth  which 
atended  from  the  meatus  nearly  to  the  corona  glandis,  or 
the  point  of  junction  of  the  glans  with  the  cervix  of  the 
penis.  This  growth  was  soft,  of  a  papillary  or  fungiform 
appearance,  and  seemed  to  involve,  to  a  moderate  extent, 
the  normal  tissue  of  the  glans.  A  portion  of  the  glans 
bad  been  removed  for  microscopic  examination.  A  simi- 
lar growth  was  seen  upon  the  prepuce,  extending  from 
the  line  of  junction  of  the  outer  and  inner  surfaces  down- 
vard  on  the  inner  surface  for  a  distance  vary  ing  from  a 
scant  half  inch  to  an  inch  in  length.  It  was  nearly  an- 
nular, forming  almost  a  complete  circle  upon  the  inner 
«irface  of  the  prepuce.  Upon  the  right  side  the  neo- 
plasm was  gradually  gaining  the  outer  surface  of  the 
prepuce,  over  which  it  extended  for  a  short  distance. 

The  specimen  was  referred  to  the  Committee  on  Mi- 
croscopy. 

lipoma  of  the  neck. 
The  third  specimen  was  a  lipomatous  tumor  removed 
from  the  neck  of  a  young  married  woman,  aged  twenty- 


three.  It  was  located  posteriorly  and  to  the  right  of  the 
median  line,  and  at  a  point  nearly  midway  between 
the  occipital  protuberance  and  the  vertebra  prominens. 
It  weighed  sixteen  drachms.  The  mass  consisted  of  a 
fibrous  capsule  which  gave  off  branches  of  fibrous  tissue 
that  filled  the  capsule  in  such  a  manner  as  to  make  it 
somewhat  cavernous.  Within  the  meshes  of  fibrous  tis- 
sue was  collected  a  large  amount  of  fat,  which  gave  to  the 
mass  a  degree  of  compressibility.  The  capsule  was  quite 
thick,  very  tough,  and  vascular,  as  could  be  readily  seen 
by  the  numerous  ligatures  on  different  portions  of  the  sur- 
face. Sections  of  the  mass  float  in  water,  giving  evidence 
of  its  lipomatous  nature.  One  or  two  small  secondary 
nodules  were  observed  around  the  periphery  of  the  mass. 
These  were  similar  in  structure  to  the  large  growth. 
The  fourth  specimen  was  an 

encysted  tumor  of  the  thigh 
situated  just  below  the  greater  trochanter,  removed  from 
a  gentleman,  aged  twenty-six.  The  tumor  was  enclosed 
in  a  firm  fibrous  capsule  which  was  partially  covered  with 
adipose  tissue.  On  section  a  white  caseous  mass  was 
seen,  which  was  readily  expressed  with  slight  pressure. 
The  cheesy  mass  was  soft  and  mushy,  disintegrating 
readily  on  pressure. 

tubercular   PERITONFTIS — GENERAL  TUBERCULOSIS. 

Dr.  W.  p.  Northrup  presented  a  specimen  with  the 
following  history :  The  patient  was  a  female,  inmate  of 
the  New  York  Founding  Asylum,  aged  three  years  and 
ten  months.  She  was  brought  in  from  the  out-nurse  in 
February,  1884.  She  was  somewhat  emaciated ;  had 
well-marked  ascites ;  bowels  inclined  to  be  constipated ; 
moderate  bronchitis.  Beyond  these  there  were  no  noted 
symptoms.  The  ascites  gave  ready  fluctuation,  but  on 
changing  the  position  of  the  child  the  fluid  did  not  move 
about  readily — seemed  to  be  encysted.  Later,  though  the 
fluctuation  continued  it  was  less  prompt  and  somewhat 
different  in  character. 

Autopsy f  ]\ine  lOf  1884. — Body:  Extremely  emaciated, 
abdomen  distended.  Brain  :  Examination  not  allowed. 
Lungs  :  Bronchial  and  tracheal  glands  enlarged  through- 
out, though  none  to  a  large  size.  Left  lung  is  adherent 
over  nearly  its  whole  surface.  In  middle  third  posteriorly 
are  two  cheesy  masses  about  the  size  of  an  ordinary  hick- 
ory-nut. Aside  from  this  the  same  description  will  serve 
for  both  lungs.  Large,  opaque,  and  glassy  miliary  tuber- 
cles are  uniformly  distributed  throughout  both.  Between 
the  .tubercles  is  a  moderate  amount  of  diffuse  pneumonia 
and  well-marked  oedema.  Heart:  Normal.  Peritoneum: 
On  opening  the  abdomen  the  muscular  wall  and  the  con- 
tents of  the  serous  membrane  are  found  glued  together. 
The  peritoneum  is  thickened  and  thickly  sprinkled  with 
cream-colored,  rounded  tubercles  about  half  as  large  as 
a  pea.  The  coils  of  intestine,  large  and  small,  liver  and 
spleen  and  stomach,  are  tightly  glued  together  into  a 
fluctuating  mass.  Fluid,  gruelly  faeces  escape  before  any 
artificial  opening  can  be  found.  In  dissecting  open  the 
intestines  a  coil  can  be  followed  for  a  few  inches  and^ 
then  it  dips  down  into  the  mass  and  is  lost.  The  whole 
mass  is  then  cut  across  and  the  half  coils  are  found 
held  in  place  by  the  gelatinous  mass  of  tubercle  and 
thickened  peritoneum,  so  that  the  cut  ends  remain  half 
patulous.  Mesenteric  glands  have  broken  down  into 
large  cheesy  masses.  Numerous  ulcers,  large  and  small, 
are  found.  Many  have  perforated  the  wall  of  the  intes- 
tine. Others  are  deeply  sunk  with  overhanging  edges. 
Liver  :  Peritoneal  covering  much  thickened,  and  contains 
large  tubercles.  On  section,  a  few  ordinary  miliary 
tubercles  are  found.  Spleen  :  Same  description  applies  to 
its  covering,  and  the  tubercles  seen  on  section.  Kidneys  : 
One  ureter  dilated  to  nearly  one-half  more  than  normal 
size  ;  three  to  five  opaque  white  miliary  tubercles  found 
on  cut  surfaces. 

Dr.  Northrup  said  he  had  seen  this  condition  of  peri- 
toneum in  young  adults,  but  never  before  in  a  child  under 
four  years.2 


48 


THE  MEDICAL  RECORD. 


[July  12,  1884- 


Dr.  Peabody  thought  the  condition  was  not  common 
in  children,  although  sufficiently  frequent  in  adults.  Al- 
though large  tubercles  of  the  peritoneum  were  not  com- 
.  nion,  large  masses  of  tubercular  tissue  were  likely  to  be 
found  wherever  tubercles  had  existed  for  a  considerable 
length  of  time. 

Dr.  J.  C.  Peters  said  that  some  time  ago  he  saw  two 
cases,  one  in  a  child  two  or  three  years  old,  and  the 
other  in  a  child  four  or  dve  years  of  age.  The  clinical 
history  was  peculiar  in  the  fact  that  the  only  symptom 
present  for  some  time  was  extreme  irritability  of  the 
bladder.  Afterward  cerebral  symptoms  developed,  and 
the  existence  of  tubercular  meningitis  was  evident  and 
was  supposed  to  be  the  principal  disease.  Both  children 
died,  after  a  sickness  lasting  about  three  weeks,  and  in 
each  there  were  tubercles  as  large  as  those  in  Dr.  North- 
rup*s  specimen,  on  the  peritoneum,  and  tubercles  in 
every  organ  seen  ;  the  brain  was  not  examined. 

Dr.  Ferguson  referred  to  a  case  of  perforation  of  the 
intestine  without  definite  symptoms,  which  he  encoun- 
tered at  an  autopsy  not  long  ago,  and  in  which  the  diag- 
nosis of  ovarian  tumor  had  been  made  by  several  gyne- 
cologists. There  was  no  ovarian  tumor  at  all,  but 
simply  a  dilated  portion  of  intestine,  which  had  ruptured 
and  emptied  the  contents  of  a  large  sac  into  the  perito- 
neal cavity  without  giving  rise  to  any  marked  symptoms. 

Dr.  C.  H.  Knight  presented  a  specimen  with  the  fol- 
lowing history : 

TUBERCULAR  MENINGITIS — HEREDITARY  SYPHILIS  ? — BASI- 
LAR  GUMMOUS    MENINGITIS? 

Jenny  M ,  aged  one  year^  was  first  seen  on  March 

24,  1884.  Had  been  fretful  and  restless  for  a  day  or  two, 
and  had  vomited  once  -,  slight  febrile  reaction  ;  symptoms 
were  thought  to  be  due  to  irritation  from  an  upper  lateral 
incisor  tooth  which  was  beginning  to  come  through. 

Five  days  later  I  was  called  to  see  the  child,  whom  I 
found  lying  with  wide-open  staring  eyes,  and  apparently 
unconscious ;  head  constantly  rolling  from  side  to  side ; 
gives  a  feeble  cry  or  whine  from  time  to  time ;  takes  no 
nourishment  without  rejecting  most  of  it  in  a  few  mo- 
ments ;  occasional  twitchings  of  extremities ;  temperature 
normal,  pulse  slow  and  regular.  Merc,  inunc.  and  K. 
I.,  gr.  j.,  every  hour. 

March  30th. — Pulse,  68,  regular ;  temperature,  99^°  F. 
in  axilla ;  refuses  to  nurse ;  has  taken  little  beef-tea  and 
milk  from  spoon  ;  lies  most  of  the  time  apparently 
asleep,  but  the  left  arm  is  in  constant  motion  between 
the  side  and  the  nose,  as  though  tr3ring  to  brush  some- 
thing from  the  face ;  left  leg  is  occasionally  drawn  up  ; 
right  side  motionless  and  flaccid ;  rolling  of  head  ceased ; 
face  pale ;  pupils  contracted,  left  more  than  right — re- 
spond slowly  to  light ;  typical  Cheyne-Stokes  respiration  ; 
no  vomiting  ;  bowels  moved  naturally  yesterday  p.m. 

March  31st. — Pulse  irregular,  95  ;  temperature,  100 J° 
F.  ;  respiration  same  as  yesterday ;  pulse  slows  during  in- 
tervals of  non-respiration  and  accelerates  with  return  of 
breathing ;  sleeps  most  of  the  time  without  moving ;  when 
*  roused  moves  only  the  left  arm  and  leg ;  left  cheek 
flushed,  right  pale ;  signs  of  iodism,  hypersecretion  nasal 
mucous  membrane ;  occasional  sneezing ;  congestion  of 
conjunctivae,  especially  right;  no  eruption. 

April  ist. — Pulse,  130 ;  respiration,  20 ;  temperature, 
101°  F.  Breathing  is  quieter  and  has  lost  the  Cheyne- 
Stokes  character ;  no  movement  of  bowels  for  three  days ; 
urine  passed  naturally ;  pupils  normal ;  no  strabismus. 

April  2d. — Pulse,  1 20 ;  temperature,  99^°  F. ;  respira- 
tion, 22  and  more  regular ;  intervals  of  rest  occur  only 
once  in  a  minute  or  so ;  child  seems  brighter  and  is  more 
easily  roused ;  takes  very  little  nourishment,  but  retains 
what  is  swallowed  ;  when  roused  is  fretful  and  makes  a 
peculiar  chewing  movement  of  the  jaw ;  movements  of 
left  arm  and  leg  continued  ;  has  a  vacant,  staring  ex- 
pression, but  the  lids  are  closed  when  the  eyes  are  ap- 
proached by  the  finger. 

April  3d. — Ophthalmoscopic  examination  attempted  by 


Dr.  Amidon ;  unsatisfactory  view  of  fundus  on  account 
of  incessant  motion  of  eyeballs ;  apparent  hyperaemia  on 
left  side ;  right  eye  wider  open  than  left ;  occasional 
twitching  of  eyelids  ;  eyeballs  constantly  moving  up  and 
down  rather  than  from  side  to  side  ;  every  few  seconds 
left  eye  is  drawn  violently  toward  the  nose  by  clonic 
spasm  of  the  internal  rectus ;  left  pupil  contracted,  right 
normal  or  dilated  and  feebly  responsive  ;  child  is  entirely 
unconscious,  but  there  is  evident  attempt  to  protect  the 
eyes  by  closure  of  the  lids  when  the  finger  or  a  bright 
light  is  brought  near ;  right  arm  and  leg  motionless  and 
flaccid,  left  arm  inclined  to  be  rigid ;  left  thigh  inces- 
santly flexed  and  extended ;  extremities  cold ;  head  bathed 
in  perspiration.  Temperature,  99**  F, ;  respiration  shallow 
and  irregular ;  period  of  rest  for  twenty  to  thirty  seconds 
followed  by  a  deep  inspiration  and  an  equal  period  of 
rapid  breathing,  at  the  rate  of  sixty  or  seventy  to  the 
mmute  ;  pulse,  140,  irregular  and  compressible  ;  bowels 
moved  this  morning  after  two  grains  of  calomel;  no 
nourishment  nor  medicine  has  been  retained  to-day; 
remained  in  above  condition  from  8  p.m.  until  5  a.m. 
April  4th,  when  the  patient  gave  a  feeble  cry  and  had 
clonic  spasms  on  the  rig/t/  side  lasting  several  minutes ; 
then  relapsed  into  previous  condition  and  died  quietly- 
at  8  A.M. 

For  the  report  of  post-mortem  and  for  microscopic 
sections,  I  am  indebted  to  Dr.  Amidon. 

Autopsy^  nine  hours  after  death, — Head  of  average  size 
and  good  shape ;  calvarium  very  thin  ;  anterior  fonta^ 
nelle  open  and  depressed,  about  three  centimetres  square ; 
scalp  and  dura  fused  at  fontanelle.  On  cutting  the  op- 
tic nerves  at  the  base,  a  quantity  of  fluid  (120  (?^  cc.) 
escaped  from  the  arachnoid  behind  the  optic  commissure, 
between  the  optic  tracts  and  the  crura  and  the  under 
surface  of  pons  and  medulla.  On  removing  the  brain 
by  section,  just  above  the  pons  more  fluid  came  from 
the  iter  and  third  ventricle.  A  diffuse  gelatinous  de- 
posit covered  the  base  about  the  optic  commissure  and 
tracts  and  about  the  points  of  emergence  of  the  crura, 
also  the  under  surface  of  the  pons,  and  to  a  slight  extent 
the  medulla,  also  the  peduncles  of  the  cerebellum  and 
the  region  of  the  cerebellum  contiguous  to  the  pons. 
This  deposit  was  in  places  three  millimetres  thick,  translu- 
cent, non-vascular,  tenacious  within  the  meshes  of  the  pia 
mater,  and  with  that  membrane  readily  stripped  from 
subjacent  tissues — in  many  places  its  surface  imparted  to 
the  finger  a  sensation  of  **  smooth  sand."  The  pons 
was  compressed  into  a  polygonal  shape  by  the  serous  ex- 
udation, and  its  tissue  was  very  hard ;  on  section  the 
lK)ns  and  medulla  appeared  to  be  normal,  with  the  ex- 
ception of  a  dilated  iter.  The  pia  mater,  on  the  con- 
volutions at  the  base  of  the  frontal,  temporal,  and  occipi- 
tal lobes,  in  the  neighborhood  of  the  gummy  deposit,  and 
especially  about  the  optic  commissure  and  between  the 
olfactory  tracts,  was  studded  with  miliary  deposits  of 
grayish-white  color,  not  connected  with  the  vessels,  ap- 
parently beneath  the  pia  yet  stripping  off*  with  it.  Con- 
vexity and  substance  of  cerebrum  normal.  Lateral 
ventricles  dilated.  Ependyma  of  all  the  ventricles  nor- 
mal.    No  other  viscera  were  examined. 

Remarks, — It  appears  that  the  father  contracted 
S)'philis  in  1877  (six  and  a  half  years  ago,  five  and  a  half 
years  before  birth  of  this  child).  He  was  treated  early 
and  continuously  for  several  years,  and  his  symptoms 
have  been  mild,  comprising  induration  of  inguinal  glands, 
erythematous  and  later  small  papular  syphiloderm,  and 
sore  throat,  all  slight  and  transient  and  within  the  first 
eighteen  months.  About  one  year  later  infection  of  the 
mother  occurred,  and  she  was  admitted  to  Roosevelt 
Hospital  in  July,  1878  (four  and  a  half  years  before  the 
birth  of  this  child).  She  was  treated  for  chancroidal  (?) 
ulceration  of  the  genitals  and  a  syphilitic  ulcer  of  the  right 
forearm  near  the  elbow,  nine  weeks  in  duration  ;  about 
six  weeks  later  she  had  an  eruption  and  lost  most  of  the 
soft  palate  by  ulceration.  Two  and  a  half  years  ago  she 
again  had  sore  throat,  ulcers  on  her  legs,  and  at  the  same 


July  12,  1884.] 


THE  MEDICAL  RECORD. 


49 


tiffle  she  lost  the  nasal  septum  and  cartilage  by  ulcera- 
tion. Since  then  she  has  had  no  symptoms  and  she  now 
seems  entirely  well.  Her  treatment  has  been  very  im- 
pexfect  and  irregular.  She  has  never  had  a  miscarriage. 
Daring  the  first  year  of  the  mother's  infection  a  child  was 
born  who  is  now  living.  He  was  quite  healthy  at  birth, 
but  nine  or  ten  months  later  he  had  ulcers  on  his  body 
and  onychia.  He  is  now  strong  and  well-nourished  but 
perhaps  a  little  under  size.  The  child  from  whom  these 
specimens  were  taken  was  born  during  the  fifth  year  of 
the  mother's  infection,  more  than  a  year  subsequent  to 
her  final  syphilitic  manifestations.  There  were  no  lesions 
at  birth,  and  when  first  seen  by  me  the  child  appeared 
tborooghly  well  nourished.  The  teeth  were  normal  in 
evolation,  shape,  and  size,  and  the  mother  insisted  that 
the  child  had  never  had  any  skin  eruption  or  other  sick- 
ness. 

Microscopical  examination  made  by  Dr.  Amidon.  The 
tubercles  consisted  of  collections  of  lymphoid  cells,  the 
central  portion  of  the  collections  being  dense  and  opaque. 
There  is  a  general  infiltration  of  the  pia  mater  (at  the 
base)  with  large  polyhedral  cells,  larger  than  white  blood- 
corpuscles.  The  translucent  material  at  the  base  of  the 
brain  consisted  of  loose  connective  tissue  holding  the 
same  cells  in  its  meshes. 

Dr.  Ajiidon  said  that  the  case  was  interesting  to  him 
especially  on  account  of  the  family  history.  It  was  sup- 
posed that  the  cerebral  trouble  was  undoubtedly  syphilitic 
in  character,  and,  at  the  autopsy,  the  gross  appearances 
resembled  those  given  by  syphilitic  rather  than  tubercular 
lesions;  but  the  microscope  revealed  that  the  lesions 
were  tubercular.  The  existence  of  miliary  collections  of 
small  cells  over  the  base  of  the  brain  should  have  con- 
yinced  them  that  the  case  was  one  of  tubercular  menin- 
gitis, but  the  clinical  history  differed  so  much  from  that 
ordinarily  met  with  in  tubercular  meningitis,  that  it,  to- 
gether with  the  peculiar  gross  appearances,  misled  him. 

Djl  Northrup  remarked  that  nystagmus  and  the 
peculiar  motion  of  the  limbs  noted  were  not  uncommon 
in  general  tuberculosis ;  so  also  the  gelatinous  exuda- 
tion at  the  base  of  the  brain.  He  regarded  the  case  as 
Qonsuaily  interesting  in  connection  with  the  syphilitic 
histoiy. 

Dr.  Peabody  said  that  the  case  was  interesting  to  him 
beause  he  saw  a  similar  one  last  winter,  occurring  in  an 
adolt,  in  whom  there  was  a  distinct  syphilitic  history.  As 
he  recalled  it  there  was  no  peculiarity  in  the  symptoms. 

At  the  autopsy  he  found  a  gelatinous  exudation  cover- 
ing the  base  of  the  brain,  and  extending  down  upon  the 
anterior  portion  of  the  cord,  from  an  eighth  to  a  six- 
teenth of  an  inch  thick,  but  with  it  no  pus  whatever. 
Microscopical  examination  failed  to  reveal  any  tubercles, 
Int  in  the  neighborhood  of  the  thick  exudation  he  found 
OMisiderable  perivasculitis  and  evidence  of  arteritis  ob- 
literans, and  the  combination  led  him  to  believe  it  to  be 
Tphilitic  in  character.  He  thought  it  perfectly  possible 
thiU  in  Dr.  Knighf  s  case  syphilis  and  tubercular  menin- 
gitis co-existed. 

Dr.  Northrup  remarked  that  in  well-developed  tuber- 
cular meningitis  a  gelatinous  layer  at  the  base  of  the 
bain  was  found  usually,  and  it  was  very  apt  to  be  tinged 
vith  a  green  color.  He  had  always  regarded  this  con- 
dition as  one  of  oedema  of  the  pia  with  a  small  quantity 
of  pas. 

Dr.  Van  Gi£SON  thought  that  the  case  ran  a  short 
ttNose  for  one  of  tubercular  meningitis.  A  gelatiniform 
cndation  is  not  infrequently  seen  m  such  cases,  and  he 
vas  of  the  opinion  that  the  quantity  depended  upon  the 
ot«nsity  of  the  inflammation  excited  by  the  tubercular 
<^posit  Chemically  it  was  nothing  more  nor  less  than 
coagidated  liquor  sanguinis.  He  had  not  noticed  the 
pecnish  tinge  spoken  of,  but  where  there  was  marked 
congestion  there  had  been,  more  frequently,  the  gelatini- 
fcnn  exudation. 
With  regard  to  the  question  whether  or  not  syphiUs 
■ay  have  been  an  etiological  factor  in  the  case.  Dr. 


Van  Gieson  thought  that  in  children  it  could  be  assumed 
with  a  peat  degree  of  certainty  of  being  true,  that  syphi- 
litic lesions  of  the  skin  will  manifest  themselves  before 
cerebral  symptoms  develop,  and  as  the  skin  in  Dr. 
Knight's  case  showed  no  lesions,  he  should  be  inclined 
to  eliminate  the  syphilitic  element  from  the  history ;  that 
view  was  also  favored  by  the  age  of  the  patient. 

Dr.  Amidon  asked  if  the  temperature  was  not  low  for 
tubercular  meningitis. 

Dr.  Van  Gieson  said  he  had  seen  quite  a  large  num- 
ber of  cases  of  tubercular  meningitis,  and  he  had  had  one 
in  which  the  disease  ran  its  course,  and  terminated  fatally, 
and  the  temperature  at  no  time  was  above  100®  F.,  taken 
in  the  rectum  with  corrected  thermometers ;  the  general 
manifestations  of  the  disease  were  extremely  characteris- 
tic. Whenever  he  was  called  to  see  a  young  child,  com- 
plaining of  headache,  lassitude,  loss  of  appetite,  with 
grating  of  the  teeth  at  night,  etc.,  and  a  temperature  of 
99°  F.,  he  at  once  suspected,  from  the  very  fact  that  the 
temperature  was  low,  that  the  life  of  the  child  was  in 
danger,  and  that  if  there  was  to  be  a  rise  of  temperature 
it  was  apt  to  be  preagonistic. 

Dr.  Amidon  regarded  the  temperature  in  Dr.  Knight's 
case  as  belonging  to  syphilis  rather  than  to  meningitis, 
and  fully  believed  that  in  all  cases  of  meningitis,  rise  of 
temperature  occurred  before  death. 

Dr.  Van  Gieson  believed  that  cases  of  tubercular  men- 
ingitis occurred,  not  uncommonly,  in  which  there  were 
only  slight  exacerbations  of  temperature.  In  deciding 
the  question  of  temperature,  he  regarded  it  as  important 
that  the  thermometer  should  be  introduced  into  the  rec- 
tum, and  allowed  to  remain  for  at  least  five  minutes. 

TUBERCULAR   MENINGITIS. 

Dr.  R.  W.  Amidon  presented  microscopic  slides  with 
the  following  history  :  Female  child,  aged  seventeen 
months.  Maternal  grandmother  died  of  chronic  pul- 
monary trouble,  after  the  age  of  fifty  years.  Some  of  the 
grandmother's  brothers  died  of  phthisis  when  younger. 
Maternal  aunt  died  recently  of  combined  cardiac  and 
pulmonary  disease.     Child's  parents  subject  to  colds. 

The  child  had  never  been  sick  before.  Was  nursed 
by  mother  until  over  a  year  old.  Was  rather  apt  to  take 
colds.  Had  a  good  deal  of  trouble  with  first  few  teeth. 
Had  be^un  to  walk  alone,  also  talked  some.  Was  a  nor- 
mally bright  child. 

About  March  15,  1884,  began  to  cut  some  back  teeth, 
which  seemed  to  cause  much  irritation.  A  week  later 
became  irritable,  disinclined  to  play,  and  resumed  creep- 
ing. Wouldn't  walk,  wanted  to  be  let  alone,  and  liked 
to  lie  down.  All  the  time  constipated.  Ate  well.  About 
March  24th  bored  pillow  a  good  deal.  Four  days  ago 
was  some  irritation  about  right  ear,  which  child  rubbed 
a  good  deal  March  26th  the  left  ear  was  likewise  irri- 
tated. The  child  was  treated  for  "teething,"  and  had 
been  given  an  unknowfi  amount  of  hyoscyamine. 

I  was  called  to  see  the  case  at  half  past  nine  on  the 
morning  of  April  5  th.  I  then  elicited  the  preceding 
history.  I  learned  that  after  a  good  nighf  s  rest  the  child 
woke  conscious,  and  immediately  (7  a.m.)  was  seized 
with  general  convulsions,  commencing  with  twitching 
of  the  face.  Spells  of  clonic  spasms  of  the  face  and 
extremities  occurred  at  intervals  from  this  time  on. 
There  was  loss  of  consciousness,  eyes  open,  fixed  and  to 
the  right,  was  feverish  before  the  convulsions.  When 
first  seen  there  was  conjugate  deviation  to  the  right,  eyes 
open  and  fixed,  pupils  dilated  (hyoscyamia)  and  equal, 
slight  occasional  twitching  about  the  left  angle  of  the 
mouth  and  almost  continuous  slight  twitchings  in  mus- 
cles of  legs  and  fore-arms.  Respiration,  60 ;  pulse  not 
perceptible  at  the  wrist,  because  of  tendinous  twitchings ; 
very  hot  and  bathed  in  warm  perspiration.  10.12  A.M.: 
temperature  in  left  axilla,  41.5°  C.  (106°  F.).  10.32: 
pulse,  120.  10.40:  respiration,  34;  temperature,  40.75° 
C. ;  began  to  give  chloral  hydrate  hypodermically  in  .10 
(two   grains)  doses,  at  intervals  of  ten  minutes.     This 


50 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


seemed  to  check  the  convulsions.  10.55  :  pulse,  108 ; 
respiration,  croupy  and  $6,  1 1.40 :  pulse,  80 ;  respira- 
tion, 76  ;  temperature,  40. 75**  C.     Died  about  noon. 

An  autopsy  revealed  the  pia  of  the  base  of  the  brain 
studded  with  miliary  tubercnles.  Rest  of  the  body  not 
examined. 

Dr.  J.  C.  Peters  had  found  the  primary  S3rmptonis  of 
tubercular  meningitis  more  variable  than  of  almost  any 
other  disease  he  had  been  called  upon  to  treat.  Some 
cases  at  the  outset  resembled  remittent  fever ;  in  others 
there  was  merely  a  slight  stiffening  of  the  neck  in  the 
morning,  which  passed  off  in  the  afternoon ;  in  some, 
projectile  vomiting  occurred  without  other  symptoms, 
and  as  almost  any  of  the  nerves  given  off  at  the  base  of 
the  brain  were  liable  to  be  involved,  a  very  great  va- 
riety of  symptoms  could  be  established.  He  knew  of  no 
disease  which  presented  difficulty  in  diagnosis  for  the 
first  four  or  five  days  equal  with  that  offered  by  tubercu- 
lar meningits. 

Dr.  J.  Lewis  Smith  thought  the  temperature  depended 
upon  the  existence  of  meningitis.  Tubercles  might  exist 
without  meningitis,  and  without  elevation  of  temperature, 
except,  perhaps,  a  rise  in  the  afternoon.  If  the  menin- 
gitis was  moderate,  the  febrile  movement  would  be  mild. 
He  could  coincide  with  Dr.  Peters'  remarks,  and  knew 
of  no  disease  of  childhood  which  was  more  difficult  to  di- 
agnosticate at  the  beginning  than  tubercular  meningitis. 

aortic  aneurism — ULCERATIVE   ENDARTERITIS — AORTIC 
INSUFFICIENCY — CONGENITAL  ANOMALIES  OF  THE  LIVER. 

Dr.  Frank  Ferguson  presented  specimens  illustrating 
the  above  lesions  removed  from  a  made,  fourteen  years  of 
age,  and  born  in  the  United  States.  Only  a  few  facts  of 
the  patient's  history  could  be  obtained.  He  did  not  give 
any  rheumatic  history.  He  had  slight  cough  for  some 
months.  Two  months  previous  to  his  admission  into  the 
New  York  Hospital  on  May  6,  1884,  he  complained  of 
shortness  of  breath,  weakness,  loss  of  appetite,  and  he 
became  pale  and  listless.  On  admission  he  was  fairly 
nourished  ;  there  was  no  oedema  of  ankles  and  legs ;  face 
looked  puffy  ;  he  was  anaemic  and  cachectic.  He  was 
very  dyspnoic  and  his  respiration  was  largely  diaphrag- 
matic. His  cardiac  action  was  rapid  and  very  irregular. 
The  precordial  area  was  increased ;  the  apex-beat  m  the 
fifth  space  and  nipple  line.  There  was  a  harsh  murmur, 
with  the  maximum  of  intensity  at  the  apex  of  the  heart, 
and  heard  with  and  after  the  first  sound.  In  the  third 
space,  just  to  the  left  of  the  sternum,  a  soft  bruit  was 
heard  with  the  first  sound.  The  second  sound  was  redu- 
plicated.    He  quietly  died  two  days  after  admission. 

The  heart  is  larger  than  normally  found  in  subjects  of 
this  age ;  its  cavities  are  dilated,  and  endocardium  is 
thickened.  There  are  vegetations  on  the  segments  of 
the  aortic  valve,  some  of  them  calcareous.  One  of  the 
segments  is  almost  entirely  destroyed.  Just  above  the 
attachment  of  the  destroyed  cusp  there  is  a  small  round 
smooth  opening  in  the  wall  of  the  aorta,  communicating 
with  a  sac  half  an  inch  in  diameter,  with  smooth  walls 
situated  in  the  upper  and  anterior  part  of  the  inter-ven- 
tricular septum. 

Above  this  aneurismal  sac  there  are  several  small  ir- 
regular ulcers  in  the  wall  of  the  aorta,  and  one  large  ulcer, 
half  an  inch  in  diameter,  with  smooth  bottom,  and  edges 
covered  with  vegetation. 

The  liver  is  ovoidal  in  shape,  left  lobe  is  rudimentary ; 
there  are  three  nodules  of  liver  tissue  on  the  under  sur- 
face of  the  right  lobe.  The  location  of  the  gall-bladder 
is  normal,  but  the  fundus  of  the  bladder  is  partially  di- 
vided by  a  septum  ;  the  organ  instead  of  being  ovoidal  or 
pyiiform,  is  triangular  in  shape.  The  microscopic  ex- 
amination of  the  liver  shows  diose  changes  which  occur 
with  cardiac  valvular  lesions. 

The  spleen  was  large,  firm,  and  pigmented.  The  kid- 
neys were  larger  than  normal,  firm  and  congested.  The 
lungs  were  congested  and  pigmented — the  condition  of 


brown  induration.    The  stomach  was  congested;  also 
the  mucous  membrane  of  the  intestines. 

CHRONIC   FIBROUS   MYOCARDmS, 

Dr.  George  L.  Peabodv  presented  a  heart  removed 
from  the  body  of  a  German  woman,  fifty-six  years  of  age, 
who  died  in  the  New  York  Hospital,  having  been  under 
observation  about  two  weeks.  The  clinical  history  was 
meagre.  The  patient  had  borne  several  children,  and 
had  been  in  comparatively  good  health  up  to  four  months 
before  her  admission,  except  that  without  known  cause 
she  began  to  suffer  from  palpitation  of  the  heart  twelve 
years  ago,  and  had  suffered  from  it,  at  intervals,  since 
that  date.  Four  months  ago  she  had  an  attack  of  pneu- 
monia which  ran  a  rather  protracted  course,  but  from 
which  she  recovered  completely.  She  entered  the  hos- 
pital with  dyspnoea,  oedema  of  the  lower  extremities  and 
lower  half  of  the  abdominal  walls,  and  also  with  marked 
ascites.  The  chief  subjective  symptom  was  dyspuoea. 
When  she  entered,  she  was  passing  about  the  normal 
quantity  of  urine,  but  the  quantity  then  diminished,  and 
it  contained  albumen  and  hyaline  and  granular  casts  in 
abundance,  and  had  a  low  specific  gravity  throughout 
At  the  autopsy  the  kidneys  presented  the  combined 
lesions  of  parenchymatous  and  interstitial  nephritis,  and 
the  liver  was  found  dislocated  entirely  below  the  firee 
border  of  the  ribs. 

The  chief  interest  centred  in  the  condition  of  the 
heart,  which  contained  a  large  amount  of  fibrous  tissue, 
especially  in  the  muscle  about  the  apex,  where  the  walls 
were  very  thin.  Microscopic  examination  showed  that, 
in  the  immediate  neighborhood  of  the  patches  of  distincdy 
fibrillated  white  fibrous  tissue,  there  was  distinct  fatty 
degeneration  of  the  muscular  tissue,  but  beyond  that  the 
muscular  wall  was  substantially  normal.  The  endocar- 
dium was  everywhere  thickened,  the  attached  borders  of 
the  aortic  cusps  were  thickened,  and  there  was  atheroma 
in  the  aorta  surrounding  the  opening  of  the  coronary 
arteries,  and  also  about  the  mitral  valve. 

Dr.  Peabody  remarked  that  he  had  not  found  fibrous 
myocarditis  without  atheroma  in  the  coronary  arteries. 

There  was  a  slight  degree  of  cirrhosis  and  2,500  cubic 
centimetres  of  flmd  in  the  peritoneal  cavity.  Clinically, 
Dr.  Peabody  thought  that  this  form  of  hypertrophy  with- 
out valvular  lesion  gave  the  patient  greater  distress  than 
any  other. 

Dr.  Van  Gieson  asked  Dr.  Peabody  if  in  such  or 
similar  cases  he  had  observed  symptoms  of  angina  pec- 
toris, as  with  calcification  of  the  coronary  arteries. 

Dr.  Peabody  replied  that  he  had  seen  two  cases. 

Dr.  J.  C.  Peters  had  seen  two  specimens  in"  which 
there  was  almost  complete  obstruction  of  the  coronary 
arteries  from  atheroma,  the  patients  having  suffered  horn 
angina  pectoris.     Both  patients  died  suddenly.     In  one  ^ 
there  was  rupture  of  the  left  ventricle. 

Dr.  Ferguson  had  had  a  case,  within  the  last  month, 
of  large  aneurism  of  the  heart  involving  a  part  of  Ac 
septum,  and  in  which  there  was  extensive  interstitial 
myocarditis  with  some  granulo-fatty  change  in  the  mus- 
cular fibre,  but  not  distinct,  and  both  coronary  arteries 
had  been  almost  completely  pbliterated  by  the  lesion  of 
endarteritis  obliterans  ;  there  was  no  atheroma.  The  his- 
tory of  the  case  extended  over  eighteen  months  and  the 
patient  was  seventy-six  years  of  age. 

Dr.  Levi  remarked  that  he  had  been  taught  that  calci- 
fication and  atheroma  were  two  distinct  conditions. 

Dr.  Peabody  remarked  that  they  did  not  necessarily 
pass  into  each  other,  but  he  thought  that  atheroma  some-* 
times  preceded  calcification. 

The  Society  then  went  into  executive  session. 


A  Munificent  Gift. — St.  George's  Hospital,  Lon^ 
don,  has  recently  received  a  bequest  of  $500,000  firom 
the  late  Mr.  William  King. 


July  12, 1884.] 


THE  MEDICAL  RECORD. 


51 


THE  PARIS  ACADEMY  OF  MEDICINE. 
Stated  Meeting^  June  10,  1884, 
M.  Alphonse  GuiRiN,  President,  in  the  Chair. 

(Special  Report  for  Thb  Medical  Record.) 

The  Academy  was  called  to  order  by  the  President,  who 
announced  the  death  of  Mme.  Richet,  and  expressed  the 
sjrmpathy  of  the  members  for  M.  Richet  in  his  affliction. 
M.  A.  FouRNiER  presented  a  communication  in  behalf 
of  M.  Duclaux  upon 

THE  MICROBE   OF  THE  BISKRA   BUTTON. 

The  coccus  in  question  was  obtained  from  the  blood 
of  a  patient  suffering  from  the  Aleppo  evil.  It  was  found 
equally  in  the  blood  flowing  from  a  puncture  made  in  the 
iflunediate  neighborhood  of  the  boil,  and  in  the  general 
circulation.  When  introduced  into  the  circulation  of  a 
rabbit  there  ensued  a  chronic  disease,  characterized  by 
successive  crops  of  boils,  gangrenous  at  their  apices,  either 
scattered  irregularly  over  the  entire  surface  of  the  body, 
or  grouped  together,  or  sometimes  even  confluent.  In 
general  appearance  they  bore  a  close  resemblance  to  the 
Biskra  button.  The  rabbits,  during  this  period  of  erup- 
tion, became  thin  and  their  fur  was  rough,  though  they 
continued  to  eat.  After  a  while  the  boils  disappeared 
and  the  animals  recovered  their  usual  health.  In  one 
case  the  eruption  began  ten  days  after  the  inoculation 
and  continued  a  mondi. 

Some  further  experiments  were  made  with  a  view  to 
deterauine  the  results  of  the 

CULTIVATION   OF  THE   COCCUS 

in  concentrated  veal  bouillon.  The  effects  of  the  injec- 
tion of  the  culture-fluid  were  found  to  vary  according  to 
the  age  of  the  cultivation  and  the  mode  of  injection. 

When  injected  under  the  skin  in  the  dose  of  twenty 
drops,  during  the  first  days  of  the  culture,  extensive 
gangrene  was  caused  Later,  when  the  fluid  was  about 
ten  days  old,  the  gangrene  was  of  limited  extent.  I^ater 
still,  localized  phlegmons  only  were  observed.  And 
finally,  two  months  or  more  after  the  commencement  of 
die  cultivation,  the  results  obtained  were  negative. 

When  the  fluid  was  injected  directly  into  a  vein  death 
ensued  at  a  period  after  the  inoculation  varying  in  length 
according  to  the  age  of  the  culture-fluid  After  two 
months  or  more  had  elapsed,  injection  into  the  veins  gave 
00  results.  But  if  a  drop  of  this  weakened  culture-fluid 
were  added  to  fresh  bouillon,  the  evidence  reappeared, 
becoming  gradually  less  and  less  as  in  the  first  series  of 
eipeinnents. 

M«  Lkgouest  remarked  that  the  disease  produced  in 
die  rabbit  by  these  inoculations  resembled  in  no  way  the 
Bidoa  button  as  seen  in  man.  In  the  former  case  the 
onpcion  was  said  to  have  lasted  a  month,  but  in  man 
^coarse  of  the  Aleppo  evil  is  of  much  longer  duration. 
¥a  this  and  other  reasons  he  doubted  whether  it  was 
tiKsune  disease  in  the  two  cases. 

if.  Blot  inquired  as  to  the  number  of  times  these  ex- 
POBnents  were  repeated  by  M.  Duclaux. 

M.  FouRNiER  was  unable  to  state  positively,  but  did 
BOt  doubt  that  they  had  been  repeated  a  sufficient  num- 
ber of  times.  He  was  certain  that  the  disease  produced 
VIS  really  the  Aleppo  evil,  and  thought  it  not  at  all  to  be 
vondered  at  that  its  manifestations  in  the  rabbit  should 
^Skl  from  those  in  man. 

M.  Colin  thought  that  the  experiments,  having  been 
andc  on  rabbits  only,  were  by  no  means  conclusive.  If 
twenty  drops  of  any  kind  of  freshly  prepared  bouillon 
ue  injected  into  a  rabbit,  extensive  gangrene  and  death 
bf  septicaemia  may  result.  Later,  when  the  animal  mat- 
ters rf  the  fluid  are  destroyed  by  putrefaction,  it  may  be 
^iijccted  with  impunity.  If  now  fresh  bouillon  is  again 
^  whether  a  drop  of  the  old  fluid  be  added  or  not,  we 
«c  the  former  series  of  results  repeated  In  order  to  be 
^^^^^dnsive,  the  injections  should  be  practised  on  larger 
^Dunab^  such  as  the  horse  or  the  ass. 


M.  Larrev  agreed  with  M.  Legouest  that  the  disease 
described  as  having  been  produced  in  rabbits  by  inocula- 
tion with  this  coccus  did  not  resemble  at  all  the  Aleppo 
evil  as  it  occurs  in  man. 

M.  BouLEY  defended  the  author  of  the  paper  from  the 
charge  of  having  confounded  the  effects  of  septicaemia 
with  those  of  the  micrococcus  of  the  Biskra  button. 
Each  animal  reacts  after  its  own  fashion  in  the  presence 
of  a  microbe,  and  it  could  not  be  expected  that  the 
symptoms  of  the  disease  in  the  rabbit  should  be  the  same 
as  those  met  with  in  the  human  being.  He  thought  the 
experiments  of  M.  Duclaux  were  particularly  interesting 
as  showing  how  the  microbe,  having  exhausted  the  nutri- 
tive elements  in  one  solution,  is  able  to  regain  new  vigor 
when  transplanted  to  a  freshly  prepared  bouillon. 

A  memoir  was  then  read  by  M.  Du  Mesnil,  candidate 
for  the  title  of  Corresponding  Member,  on 

concussion  of  THE  SPINAL  CORD,  SCLEROSIS  OF  THE 
LATERAL  COLUMNS,  AND  DEGENERATION  OF  THE  CELLS 
OF  THE  GRAY  SUBSTANCE. 

His  conclusions  were  that :  i,  Concussion  of  the  spinal 
cord  is  a  condition  the  existence  of  which,  in  the  present 
state  of  science,  ought  to  be  maintained ;  2,  it  may  be  the 
starting-point  for  secondary  inflammatory  lesions ;  3, 
these  inflammatory  lesions  may  assume  the  form  of  cir- 
cumscribed myelosclerosis. 

M.  L^ON  Labb£  then  read  a  paper  entitled 

INTRA-ARTICULAR  IRRIGATION  WITH  CARBOLIZED  WATER 
IN  THE   TREATMENT   OF   CHRONIC  HYDRARTHROSIS. 

After  reviewing  briefly  the  various  attempts  made  to  cure 
chronic  hydrarthrosis  by  intra-articular  injections  of  dif- 
ferent substances,  the  author  described  the  procedure 
known  as  Schdde's  operation.  This  consists  in  punctur^ 
ing  the  articulation  with  a  trocar  of  wide  calibre,  forc- 
ing out  the  fluid,  and  then  injecting  a  three  to  five  per 
cent,  solution  of  phenic  acid.  A  large  quantity  of  the 
solution  is  used,  and  the  injections  are  repeated  until  the 
water  flows  away  perfectly  clear.  The  wound  made  by 
the  trocar  is  then  sealed  with  gold-beaters*  skin  and 
collodion,  the  joint  is  enveloped  in  a  thick  layer  of  wad- 
ding, and  the  limb  is  immobilized  in  a  guttered  splint. 
Strict  antiseptic  precautions  are  observed,  and  the  great' 
est  care  is  taken  to  prevent  the  entrance  of  air  into  the 
articulation  during  the  operation.  The  author  had  seen 
Sch^de  perform  this  operation,  and  had  himself  operated 
upon  two  patients  with  success. 

M.  Jules  GufiRiN  regretted  that  M.  Labb^,  in  his 
review  of  other  modes  of  treatment,  had  not  mentioned 
the  one  iijrhich  had  given  in  general  the  best  results  of 
any.  This  method,  which  he  had  employed  for  a  period 
of  thirty-five  years,  was  divided  into  three  parts,  corre- 
sponding to  the  three  stages  of  the  disease.  At  the  com- 
mencement of  the  disease,  the  treatment  from  which  the 
best  results  are  obtained  is  by  vesication.  Later,  when 
the  affection  has  lost  iii  a  measure  its  acute  character, 
cold  water  is  indicated  Finally,  in  the  third  and  chronic 
stage,  the  treatment  by  means  of 

punctate  cauterizations 
is  the  one  which  is  the  most  effectual  in  overcoming  the 
disease.     These  cauterizations  are  a  matter  of  every-day 
occurrence  now,  but  it  was  far  otherwise  thirty  or  more 
years  ago. 

M.  Colin  claimed  that  the  veterinary  surgeons  were 
the  first  to  make  use  of  the  cautery  in  the  treatment  of 
joint  diseases,  and  that  the  surgeons  of  to-day  were 
merely  imitators  of  the  veterinarians  in  this  respect. 

M.  GufiRiN  said  that  punctate  cauterization  was  a 
very  different  procedure  from  burning  by  hot  irons  as 
practised  by  veterinary  surgeons.  In  the  former  case 
the  burn  was  very  superficial  and  never  caused  suppura- 
tion. Punctate  cauterization,  therefore,  both  in  its  mode 
of  employment  and  in  its  effects,  was  essentially  a  new 
method 

The  Academy  then  adjourned. 


52 


THE  MEDICAL  RECORD. 


Duly  12, 1884. 


THE  ROYAL   IMPERIAL    MEDICAL    SOCIETY 

OF  VIENNA. 

Stated  Meetings  May  30,  1884. 
Professor  Leidesdorf,  President,  in  the  Chair. 

(Special  Report  for  Thk  Mbdical  Rrcosd.) 

The  Society  having  been  called  to  order  by  the  Presi- 
dent, Dr.  Hofmokl  exhibited  some  patients  upon  whom 
he  had  recently  operated.  The  first  case  was  one  show- 
ing the  results  of 

OSTEOTOMY  OF   THE   FEMUR 

for  knock-knee.  The  operation  was  performed  after 
Massini's  method,  and  resulted  in  a  perfect  correction  of 
the  deformity. 

The  second  patient  had  suffered  for  twelve  years  from 
symptoms  of 

vesical  calculus. 
The  median  operation  was  performed,  and  an  enor- 
mous stone  was  removed  after  crushing.  It  had  nearly 
filled  the  bladder.  It  was  composed  chiefly  of  lime  salts 
with  a  nucleus  of  uric  acid.  The  patient  was  now  well, 
except  that  he  was  unable  to  retain  his  water  for  any 
great  length  of  time  because  of  the  paresis  of  the  bladder, 
which  still  existed. 

A  third  patient  was  shown,  who  suffered  from 

REPEATED    BREAKING   DOWN    OF   A   CICATRIX. 

A  stone  had  been  removed  from  his  bladder  by  the 
high  operation  three  years  before.  Since  that  time  the 
cicatrix  had  yielded  seven  different  times.  There  was 
no  stricture  of  the  urethra  discoverable,  though  there 
was  always  considerable  straining  in  passing  water.  When 
the  cicatrix  was  about  to  break,  it  would  be  seen  to 
swell  out  like  a  toy  balloon,  would  then  burst,  and  the 
urine  would  flow  out  through  the  anterior  abdominal 
wall.  These  repeated  occurrences  had  become  almost 
unbearable,  and  the  patient  had  already  made  one  at- 
tempt to  taJce  his  own  life. 

Professor  V.  Dittel  exhibited  to  the  Society  an 
apparatus,  devised  by  Dr.  Silbermann,  of  Breslau,  for  the 

temporary  closure  of  one  ureter. 

It  is  a  matter  of  great  importance  to  the  surgeon  con- 
templating the  removal  of  a  kidney  to  determine  whether 
the  other  is  healthy  and  capable  of  secreting  urine.  It 
has  hitherto  been  nearly  impossible  to  determine  this 
with  any  certainty  owing  to  the  difficulty  of  obtaining 
the  urine  of  one  kidney  unmixed  with  the  secretion  of 
the  other.  The  attempt  has  been  made  to  catheterize 
the  ureter,  and  has  been  successfiil  in  the  case  of  women 
after  dilatation  of  the  urethra,  but  in  man  this  is  impos- 
sible. Dr.  Silbermann' s  instrument  consists  of  a  cath- 
eter (No.  18  French)  provided  with  a  large  opening  if 
inches  long,  upon  the  side,  and  several  small  holes  at  its 
extremity.  The  instrument  having  been  introduced,  the 
eye  being  covered  so  as  not  to  injure  the  walls  of  the 
urethra,  a  smaller  canula  is  passed  through.  This  small 
tube  is  provided  with  a  rubber  ball  at  its  extremity,  which, 
when  in  position,  lies  directly  in  the  eye  of  the  catheter. 
The  instrument  being  so  turned  that  this  part  lies  against 
the  mouth  of  the  ureter,  mercury  is  forced  through  the 
inner  tube,  dilating  the  rubber  ball  and  effectually  clos- 
ing the  orifice.  Thus  the  urine  that  passes  into  the 
bladder  can  come  from  one  ureter  only,  and  a  few 
minutes  will  suffice  to  show  whether  the  corresponding 
kidney  is  performing  its  functions  normally.  The  instru- 
ment has  been  tried  several  times  in  healthy  individuals 
and  has  been  found  to  answer  the  purpose  intended. 

Professor  Mauthner  then  exhibited  a  patient  with 

OPHTHALMOPLEGIA   INTERIOR, 

or  paralysis  of  the  muscle  of  accommodation  and  sphincter 
iridis,  with  preservation  of  function  of  the  external  mus- 
cles of  the  eye.     After  the  reading  of  a  paper  on 

CEPHALOMETRY   AND    CRANIOMETRY 

by  Professor  Benedikt,  the  Society  adjourned. 


THE   BERLIN    SOCIETY    OF   INTERNAL 
MEDICINE. 

Stated  Meetings  May  26,  1884. 

Herr  Leyden,  President,  in  the  Chair. 

(Special  Report  for  Thb  Msdicax.  Rbcokd.) 

The  first  paper  of  the  evening  was  read  by  Herr  G. 
Bshrend  upon  the 

nature  of  prurigo. 

The  author  took  exception  to  the  teaching  of  the  Vi- 
enna  school  that  skin  diseases  are  essentially  local  affec- 
tions, and  maintained  that  they  may  arise  from  changes 
in  the  blood,  or  may  be  symptoms  of  some  general  dis- 
ease. In  proof  of  this  position  he  cited  the  eruptions 
that  are  often  seen  to  follow  the  long-continued  use  of 
certain  drugs,  and  those  occurring  in  nephritis,  or  in  the 
'exanthematous  diseases.  These  eruptions,  he  stated,  are 
independent  of  the  nature  and  specific  action  of  the  mat- 
ters under  whose  influence  they  arise.  Hence  they  may 
be  called,  and  were  so  called  by  the  author  himself,  in  his 
work  on  dermatology, 

HiCMATOGENETIC   ERUPTIONS  OF  THE   SKIN. 

No  direct  evidences  of  the  haematogenetic  origin  of 
prurigo  have  hitherto  been  forthcoming,  but  the  speaker 
had  recently  observed  two  cases  which  seemed  to  supply 
the  omission. 

The  first  was  that  of  a  child,  seven  and  a  half  years  of 
age,  who  had  had  scarlatina  some  two  years  and  a  half  ago. 
It  had  previously  been  a  healthy  child  with  a  complexion 
free  from  any  appearance  of  eruption.  Just  as  the  des- 
quamatory  stage  was  at  an  end  there  was  a  thick  eruption 
of  pustules,  most  noticeable  on  the  lower  extremities,  but 
present  also  on  the  body  and  arms.  As  these  pustules 
dried  a  new  crop  appeared,  and  then  another,  and  another 
for  some  eight  or  ten  weeks.  When  this  pustular  erup- 
tion ceased  a  prurigo  appeared,  and  still  existed  at  the 
time  of  the  report.  The  eruption  occupied  the  extensor 
surfaces  of  the  articulations  chiefly,  and  was  entirely  ab- 
sent from  the  flexor  surfaces.  There  was  also  some  pig- 
mentation of  the  skin,  and  swelling  of  the  inguinal  glands. 

The  second  case  was  a  seven-year-old  boy,  who  had 
had  scarlet  fever  and  secondary  nephritis  three  years  pre- 
viously. When  first  seen  some  months  after  the  subsi- 
dence of  the  original  disease,  he  was  suffering  from  well- 
marked  and  typical  prurigo.  The  mother  stated  that  a 
pustular  eruption  was  first  seen,  which  gradually  disap- 
peared and  gave  place  to  the  prurigo. 

The  speaker  maintained  ttiat  the  scarlatinal  poison 
had  first  given  occasion  to  the  development  of  the  pru- 
rigo, though  the  latter  had  remained  after  the  cause  had 
been  removed  from  the  system.  A  similar  occurrence 
is  seen  in  the  persistence  of  an  eczema,  following  vac- 
cination, long  after  the  influence  of  the  vaccine  virus 
upon  the  organism  has  ceased. 

Herr  Lewinski  thought  the  prurigo  was  due  to  the 
inflammation  of  the  skin  accompanying  scarlatina  rather 
than  to  the  scarlatinal  poison. 

Herr  Behrend  rejected  this  view  and  maintained 
that  the  localization  of  the  eruption  upon  the  extensor 
surfaces  of  the  joints,  as  well  as  the  pigmentation  of  the 
skin,  were  sufficient  to  establish  the  correctness  of  his 
diagnosis.  He  regarded  the  pustular  eruption  as  the 
transition  stage  between  scarlatina  and  prurigo. 

Herr  Kronecker  presented  an  account  of  some  ex- 
periments made  by  himself  and  Herr  Schmey,  in  the 
course  of  which  they  had  accidentally  discovered  the 

centre  of  co-ordination  for  the  ventricular 
pulsations. 

The  experiments  were  being  conducted  with  a  view  of 
establishing  the  mode  of  contraction  of  the  ventricles. 
A  dog  was  put  under  the  influence  of  curare,  artificial 
respiration  being  maintained  while  the  heart  was  exposed 
and  raised  up  to  the  opening  in  the  thorax.     The  reg- 


July  12,  1884.] 


THE  MEDICAL  RECORD. 


53 


istering  apparatus  being  ready,  Herr  Kronecker  thrust  a 
needle  into  the  heart  in  order  to  record  its  movements. 
At  that  instant  the  ventricles  ceased  pulsating,  dilated, 
ind  presented  only  irregular  fibrillary  twitchings.  The 
needle  was  removed  at  once  and  the  heart  was  kneaded, 
but  without  avail.  The  auricles  continued  to  pulsate,  but 
the  animal  died  without  a  single  beat  of  the  ventricles 
occnrring.  This  accident  led  to  further  investigations, 
in  which  the  experimenters  found  that  an  injury  to  the 
cardiac  wall  at  a  certain  point  invariably  caused  paralysis 
of  the  ventricles.  This  point,  the  limits  of  which  were 
not  yet  exactly  mapped  out,  was  over  the  lower  bound- 
ary of  the  upper  third  of  the  ventricular  septum  near  the 
descending  branch  of  the  left  coronary  artery.  Here, 
then,  must  be  the  distributing  point  for  the  nerve-supply, 
the  part  where  the  messages  to  the  different  muscular 
fibres  are  arranged  and  co-ordinated,  so  that  each  por- 
tion of  the  ventricular  wall  shall  contract  in  harmony 
with  every  other  portion.  When  this  centre  is  destroyed 
the  separate  muscular  bundles  do  not  contract  with  less 
force  but  irregularly. 

Experiments  were  also  made  to  determine  the  effects 
of  irritation  upon  this  newly-discovered  co-ordinating 
centre.  It  was  found  that  a  very  weak  induced  current 
passed  through  this  point  was  sufficient  to  arrest  the 
rhythmic  pulsations  of  the  ventricle.  But  if  the  elec- 
trodes were  placed  at  a  distance  from  this  centre  it 
required  a  current  of  much  greater  strength  to  produce 
the  same  effect.  Herr  Kronecker  thought  that  the  cases 
of  sudden  death  from 

PARALYSIS   OF  THE   HEART 

were  to  be  explained  through  this  excessive  vulnerability 
of  the  co-ordinating  centre  In  sclerosis  of  the  coronary 
arteries,  fatty  degeneration,  and  sometimes  during  con- 
valescence from  acute  diseases,  sudden  death  from  par- 
alysis of  the  heart  has  been  observed.  In  such  cases 
the  individual  may  breathe  several  times  after  the  car- 
diac pulsations  are  no  longer  perceptible.  It  is  fortu- 
oate  that  this  centre  is  situated  in  a  part  of  the  ventricu- 
lar wall  so  well  protected  from  external  injuries. 

In  concluding,  the  speaker  reminded  bis  hearers  that 
these  experiments  were  made  upon  dogs  only,  and  it  was 
very  probable  that  tlie  centre  of  co-ordmation  in  the  ani- 
mals of  a  lower  order  was  not  so  strictly  defined.  This 
should  be  borne  in  mind  if  similar  experiments  were 
made  on  rabbits  or  frogs,  otherwise  the  results  obtained 
might  appear  to  conflict  with  his  own. 

The  Society  then  adjourned. 


A  Criticism  from  India  on  the  Cholera  Bacillus. 
-The  Indian  Medical  Gazette^  in  the  course  of  an 
daborate  review  of  Koch's  work  and  discovery,  says : 
"A review  of  the  whole  evidence  brought  forward  by  the 
Genoan  Cholera  Commission  shows  that  they  have  only 
sncoeded  in  establishing  the  fact  that  a  peculiar  form  of 
badllus  is  normal  to  the  intestines  of  cholera  patients ; 
bat  the  exact  part  which  this  organism  plays  in  the  mor- 
bid process  is  left  wholly  undetermined.  Only  a  very 
moderate  degree  of  probability  has  been  made  out  in 
bor  of  this  bacillus  being  the  cause  of  cholera ;  but  the 
Mity  of  trusting  to  probabilities  and  conjecture  in  an 
etiological  inquiry  into  cholera  is  generally  well  recog- 
aittd.  The  problem,  therefore,  of  the  causation  of 
diolcra  still  remaining  unsolved,  it  awaits  and  ought  to 
receive  that  careful  attention  which  its  great  importance 
iiemands."  It  is  not  fair  to  depreciate  the  value  of  Koch's 
<fiscovery ;  but,  on  the  other  hand,  it  will  do  no  good  to 
give  to  it  any  greater  weight  than  the  evidence  strictly 


Th£  Number  of  the  Blind  in  Russia  is  unusually 
peat,  amounting  in  some  districts  to  .2  per  cent  of  the 
population. 


THE  THERAPEUTICAL  SOCIETY   OF   PARIS. 

Stated  Meeting,  May  28,  1884. 

M.  Delpech,  President,  in  the  Chair. 

(Special  Report  for  Thx  Mkdical  Rbcord.) 

After  the  Society  had  been  called  to  order,  M.  Petit 
exhibited  some  specimens  of 

euphorbia  pilulifera. 

This  plant,  which  resembles  the  ordinary  wartwort  {r^eille- 
matin),  grows  in  stony  places  in  the  neighborhood  of 
Brisbane,  Australia.  It  is  used  in  that  country  and  in 
England  in  asthma  and  all  chronic  spasmodic  bronchial 
affections.  An  infusion  is  made  of  one  ounce  of  the 
fresh  plant  in  three  and  a  half  pints  of  water,  of  which  the 
dose  is  a  glassful  morning  and  evening.  M.  Petit  offered 
to  furnish  samples  of  the  dried  plant  to  any  of  the  mem- 
bers who  might  desire  to  experiment  with  it. 

M.  E.  Labb£  continued  some  remarks  which  he  had 
made  at  the  previous  meeting  upon  the  properties  of 

ozonifacient  water. 

This  product,  which  may  be  extracted  from  the  pinus 
maritinuiy  was  discovered  by  M.  Boursier,  and  is  really  a 

terebinthinb  hydrate. 

Its  ozonifacient  properties  give  to  it  a  special  value  as 
a  disinfectant.  It  may  be  used  in  the  form  of  spray, 
vapor,  or  as  a  liquid.  If  the  spray  be  directed  over  any 
putrefying  and  foul-smelling  material  the  fetid  odor  is  at 
once  destroyed.  The  vapor  possesses  a  terebinthinate 
odor,  and  would  seem  to  be  indicated  in  the  case  of  fetid 
expectoration.  The  vapor  is  certainly  absorbed  by  the 
respiratory  mucous  membrane,  for  when  inhaled  for  any 
length  of  time  symptoms  of  intoxication  are  produced. 
In  the 

treatment  of  diphtheria 

a  wash  of  ozonifacient  water  has  appeared  to  give  good 
results,  but  the  trials  of  the  remedy  in  this  disease  have 
been  too  few  to  allow  of  any  definite  conclusions.  Com- 
presses wet  with  the  substance  and  applied  to  any  sur- 
face giving  off  a  fetid  secretion  are  productive  of  good 
results.  The  speaker  thought  that  this  product,  owing 
to  its  cheapness  and  the  small  quantities  which  it  is 
necessary  to  employ,  was  destined  to  assume  the  first 
rank  among  the  disinfectants. 

M.  Blondeau  remarked  upon  the  strong  terebinthinate 
odor  of  the  substance,  and  suggested  that  it  owed  its  dis- 
infectant properties  to  the  turpentine  which  it  contained. 

M.  Labb:^  maintained  that  turpentine  had  no  such 
ozone-producing  properties  as  the  product  in  question 
was  shown  to  possess. 

M.  Dujardin-Beaumetz  exhibited  some  fresh  and 
dried  specimens  of  the 

kola  nut, 

the  fruit  of  the  sterculia  acuminata,  a  tree  growing  in 
Central  Africa.  The  natives  look  upon  it  as  a  universal 
cure-all,  and  attribute  to  it  tonic,  nutritive,  excitant,  and 
aphrodisiac  properties.  Analysis  shows  that  kola  con- 
tains caffeine  and  tannin  in  large  proportions  and  a  rel- 
atively less  amount  of  theobromine.  It  has  been  used 
with  success  in  the  diarrhoeas  of  hot  climates,  in  cardiac 
diseases,  and  as  a  tonic. 

M.  Petit  asked  whether  the  beneficial  effects  of  the 
kola  nut  were  not  due  to  the  caffeine  contained  in  it,  and 
thought,  if  this  were  so,  it  would  be  much  better  to  use 
the  latter  drug  by  itself  than  to  give  it  mixed  with  other 
inert  substances  in  the  form  of  kola  preparations. 

M.  Dujardin-Beaumetz  then  made  a  few  remarks 
upon 

HAMAMELIS   VIRGINIANA. 

He  said  that,  while  not  agreeing  with  those  who  thought 
no  substance  could  possess  valuable  therapeutic  prop- 
erties which  was  not  poisonous  in  large  doses,  he  must 


54 


THE  MEDICAL  RECORD. 


[July  12,  1884. 


nevertheless  say  that  he  had  never  been  able  to  observe 
even  any  physiological  effects  from  witch-hazel. 

M.  Campardon  related  two  instances  in  which  he  had 
observed  a  gradual 

DECOLORATION   OF  PIGMENTED   SPOTS, 

due  to  varicose  veins,  following  the  internal  administra- 
tion of  an  infusion  of  hamamelis.  In  neither  case  was 
the  remedy  applied  locally. 

After  some  further  remarks  by  the  members  regarding 
the  parts  of  the  plant  in  which  the  active  principle  was 
contained,  the  Society  adjourned. 


OUR   LONDON   LEITER. 

(From  oae  Special  Correspondent.) 

SIR  JAMES  facet's  ADDRESS  AT  THE  HEALTH  EXHIBI- 
TION — THE  CONSERVATORSHIP  OF  THE  COLLEGE  OF 
SURGEONS — BURIAL  ALIVE — OVERPRESSURE  IN  SCHOOLS 
— STATE  OF  THE  THAMES — SMALL-POX  IN  LONDON — 
CONFERENCE    ON   SANITARY   LEGISLATION. 

London,  June  ar,  1884. 

On  Tuesday  last,  June  1 7th,  the  Prince  of  Wales  paid 
his  first  visit  to  the  International  Health  £xhibition,  and 
on  this  occasion  an  address  was  delivered  by  Sir  James 
Paget  in  his  usual  felicitous  manner.  Sir  James  depre- 
cated mere  comfortable  idle  health.  The  pattern  healthy 
man  was,  he  said,  one  who  lived  long  and  vigorously  ; 
who  in  every  part  of  his  life  did  the  largest  amount  he 
could  of  the  best  work,  and  when  he  died,  left  healthy 
offspring. 

Referring  to  published  statistics,  Sir  James  Paget 
pointed  out  some  striking  facts.  He  estimated  that 
in  this  country  the  whole  population  between  fifteen  and 
sixty-five  years  of  age  do,  in  each  year,  twenty  million 
weeks'  less  work  owing  to  sickness.  He  remarked  that 
typhoid  fever  alone  destroyed  4,000  working  people  a 
year  in  England  and  Wales.  From  this  one  preventable 
disease  we  had  an  annual  loss  of  230,000  weeks'  work 
from  illness.  Referring  to  infantile  mortality  Sir  James 
remarked  that  in  1882  the  mortality  of  children  under 
fifteen  was  nearly  a  quarter  of  a  million.  If  you  reck- 
oned that  each  child  cost  only  ^^8,  more  than  two 
million  pounds  sterling  were  thus  lost  every  year.  But 
they  had  cost  much  more,  and  much  more  still  was  Ipst 
by  the  loss  of  the  work  they  might  have  lived  to  do. 
The  numerous  diseases  that  might  be  prevented  by  suit- 
able precautions  were  then  referred  to,  and  Sir  James 
Paget  concluded  by  urging  that  we  wanted  more  am- 
bition for  renown  in  health.  He  would  like  to  see  a 
personal  ambition  for  renown  in  health  as  keen  as  that 
for  bravery,  or  for  beauty,  or  for  success  in  our  athletic 
games  and  field  sports ;  as  for  national  renown  in  war, 
or  in  arts  or  commerce. 

Mr.  Stewart,  of  St.  Thomas'  Hospital,  has  been 
elected  to  the  Conservatorship  of  the  College  of  Sur- 
geons, vacant  through  the  resignation  of  Professor 
Flower,  who  was  appointed  to  the  Natural  History  Mu- 
seum some  months  since. 

A  controversy  has  been  going  on  lately  in  the  columns 
of  Tkg  Lancet  as  to  the  possibility  of  persons  being 
buried  alive.  Some  of  the  correspondents  deny  the  pos- 
sibility of  this  occurrence  altogether.  Some  of  the  facts 
narrated  by  others  seem  to  show  that  it  has  occurred 
even  in  the  present  century.  It  is  very  pertinently 
pointed  out  that  burial  should  not  be  permitted  till  some 
signs  of  decomposition  have  appeared.  A  good  deal  of 
discussion  took  place  some  years  ago  as  to  various  *'  signs 
of  death,"  but  no  more  reliable  sign,  and  one  of  such 
easy  application,  has  as  yet  been  pointed  out. 

Overpressure  in  education  is  again  denounced  by 
sanitary  authorities.  The  system  of  payment  by  results 
seems  partly  to  blame  in  Board  Schools.     This  makes  it 


the  direct  interest  of  the  teachers  to  force  as  many  pu- 
pils as  possible  up  to  a  given  standard,  and  tends  to 
press  hardly  on  the  weaker  or  duller  members  of  a  dass. 
But  overwork  is  not  confined  to  Board  Schools,  nor  to 
students  of  tender  age.  Every  now  and  then  we  hear  of 
suicides  among  university  and  other  students  attributed 
to  overwork  for  competitive  and  other  examinations. 

The  condition  of  the  Thames  during  the  last  week  is 
presumably  due  to  the  unusual  dryness  of  the  season. 
Between  Twickenham  and  Kew  the  bed  of  the  river  has 
been  exposed  at  low  water,  and  children  have  actually 
crossed  on  foot  from  one  side  to  the  other.  The  river  is 
said  to  be  getting  shallower  day  by  day.  Should  this 
prove  to  be  the  case,  the  intra-metropolitan  portion  of 
the  stream  can  scarcely  fail  to  be  afifected.  The  stagna- 
tion of  sewage  at  Barking  and  Crossness  will  probably 
become  more  offensive,  and  other  dangers  to  health  are 
likely  to  ensue. 

Small-pox  is  still  on  the  increase  in  London.  Last 
week  (ending  June  14th)  the  number  of  patients  under 
treatment  in  the  hospitals,  hospital-ships,  and  convales- 
cent camp  of  the  Metropolitan  Asylums  Board  rose  to 
1,238,  being  an  increase  of  142  on  the  preceding  week. 
The  number  of  new  cases  admitted  during  the  week  was 
332.  Owing  to  the  further  increase  in  the  number  of 
patients  under  treatment,  it  has  been  found  necessary  to 
lease  a  hospital  belonging  to  the  Poplar  Board  of  Works. 
It  is  cheering  to  note  that  the  deaths  from  small-pox  in 
London  during  the  same  week  were  only  30  in  number. 

A  Conference  on  sanitary  legislation  will  be  held  next 
week  at  the  Health  Exhibition.  It  will  last  two  days, 
and  be  under  the  auspices  of  the  Social  Science  Asso- 
ciation. 

OUR  PARIS   LETTER. 

(From  our  Special  ConreqxmdcaL) 
REMOVAL  OF  CONTAGIOUS  DISEASES  TO   HOSPITAI.S — HOW 
IT    IS    DONE    IN    PARIS — THE    NEW    METHOD    FOR    THE 
TRANSFUSION    OF    BLOOD — A  CURIOUS  CASE   OF   MALIN- 
GERING— HOW  A  THERMOMETER  WAS  TAMPERED  WITH. 

Paxis,  June  30, 1884. 

A  VERY  useful  measure  has  been  taken  by  the  Pre- 
fect of  police  with  reference  to  the  removal  of  persons 
suffering  from  contagious  diseases  to  the  hospitals  from 
their  own  homes.  Special  carriages  have  been  con- 
structed for  the  purpose  which  are  kept  at  the  H6tel 
Dieu,  and  he  has  informed  the  commissaries  of  police  of 
each  district  that  all  that  will  be  required  is  a  medical 
certificate  as  to  the  nature  of  the  malady  of  the  appli- 
cant, giving  his  name  and  address.  These  carriages  are 
placed  at  the  disposal  of  the  public  daily  from  8  a.m.  to 
6  P.M.,  and  in  order  to  get  one  application  must  be  made 
to  the  commissary  of  police  of  the  quarter  in  which  the 
patient  resides,  or  to  the  central  police  office  of  the  dis- 
trict No  charge  will  be  made  for  the  use  of  these  car- 
riages, and  the  commissaries  of  police  are  further  in- 
structed thoroughly  to  disinfect  the  carriages  after  each 
journey,  and  also  to  disinfect  the  room  from  which  the 
patient  has  been  removed.  Hitherto  these  carriages 
were  reserved  for  small-pox  patients  only,  but  they  are 
now  to  be  available  for  all  contagious  or  epidemic  mala- 
dies, such  as  small-pox,  scarlet  fever,  measles,  diphtheria^ 
etc.  This,  as  I  have  said,  is  certainly  a  very  useful 
measure,  but  unless  the  public  are  made  acquainted  witli 
such  an  arrangement  in  a  more  efficient  manner  these 
carriages  will  scarcely  ever  be  called  into  requisition,  as 
has  happened  with  the  ambulance-carriage  reserved  for 
small-pox  patients,  as  the  public  being  ignorant  of  its 
existence  for  the  last  two  years,  it  is  reported  that  it  was 
taken  advantage  of  only  ten  times  during  that  period. 

At  a  recent  meeting  of  the  Academy  of  Sciences  Pro- 
fessor Vulpian  read  a  paper  for  M.  Afanassiew,  a  Rus- 
sian physiologist,  on  a  new  method  for  the  transfusion  of 
blood,  which  consists  of  peptonizing  the  latter,  by  which 
means  its  coagulability  is  suppressed  for  a  certain  time. 


July  12, 1884.] 


THE  MEDICAL  RECORD. 


55 


M.  Afanassiew  acquired  the  knowledge  of  this  fact  by 
experiments  he  had  performed  on  dogs,  from  which  he 
itmoved  two-thirds  of  their  blood,  which  reduced  them 
to  death's  door.  In  injecting  into  their  veins  blood 
Qiixed  with  peptones,  he  was  enabled  to  restore  them  to 
life.  Accoiding  to  the  author  these  peptones  do  not  in 
any  way  affect  the  globular  elements  of  the  blood ;  the 
peptones  simply  prevent  coagulation,  and  thus  render 
aseless  the  process  of  defibrination  before  injecting  the 
blood  M.  Afanassiew  promises  to  continue  his  experi- 
ments on  animals  before  venturing  to  apply  his  new 
method  to  man. 

A  very  curious  case  of  malingering  was  recently  brought 
to  the  notice  of  the  Soci^te  M^icale  des  Hdpitaux 
by  Dr.  Du  Castel,  which  was  detected  in  a  young  woman 
in  a  hospital  under  the  following  circumstances  :  She 
iras  admitted  for  a  herpetic  disease  of  the  throat,  and  in 
going  into  her  previous  history  she  stated  that  she  had 
had  an  attack  of  pneumonia,  which,  however,  was  con- 
sidered doubtful,  as  she  had  recently  had  an  attack  of 
hemoptysis.  She  had  never  had  convulsions.  At  the 
end  of  five  or  six  days,  the  sore  throat  was  almost  com- 
pletely cured,  and  the  temperature  of  her  body,  which 
bad  risen  to  39.5^  C,  fell  to  nearly  normal ;  but  she  was 
seized  with  an  attack  of  delirium  followed  by  great  ex- 
citement which  lasted  several  hours.  A  few  days  later, 
the  patient  declared  that  she  had  spit  up  a  good  deal  of 
'^ thick  matter"  during  the  night,  which  nobody  saw,  as 
she  had  emptied  her  spittoon  before  the  doctor's  visit. 
Soon  after  this,  she  presented  symptoms  of  coma,  ac- 
companied with  a  slight  increase  of  the  temperature. 
This  was  followed  by  complete  paraplegia  accompanied 
with  generalized  hyperaesthesia.  Finally  followed  a  series 
of  hysteriform  attacks,  distinctly  marked  aphasia,  mutism, 
etc,  the  thermometer  ranging  at  this  time  from  39°  C. 
to  39-5°  ^-  '^^^  physician  hesitated  in  his  diagnosis  of 
hysteria,  and  he  felt  inclined  to  ask  himself  whether, 
owing  to  the  deafness  which  existed  during  the  attack  of 
sore  throat  followed  by  spitting  up  of  matter  (?),  there 
was  not  some  lesion  of  the  internal  ear  complicated 
with  cerebral  abscess.  This  state  of  uncertainty  lasted 
some  time,  when  one  morning  the  interne  charged  to 
take  the  temperature  of  the  patient  observed  to  his  sur- 
prise that  the  thermometer  marked  43.4°  C.  It  was 
imagined  that  there  might  have  been  some  error,  and  the 
temperature  was  again  taken,  when  the  thermometer 
marked  39°.  Eight  days  later  the  thermometer  marked 
43°  and  a  few  tenths,  then  the  temperature  remained  for 
1  few  days  after  about  39^.  One  morning  the  ther- 
mometer marked  44^.  Thi$  naturally  puzzled  the  interne 
jfid  the  physician,  when  it  was  resolved  to  examine  all 
the  thermometers  of  the  ward,  but  nothing  wrong  was 
detected;  nevertheless  the  temperature  as  taken  each 
day  was  sometimes  38°,  sometimes  43°,  and  sometimes 
}ff  C,  but  the  rise  or  fall  was  the  same  whether  the 
kraiometer  was  applied  to  the  axilla  or  in  the  vagina, 
ttddie  thermometer  had  even  risen  to  48°.  Suspecting 
50oe  trickery  on  the  part  of  the  patient,  she  was  closely 
vaidied,  and  as  it  appeared  to  the  physician  that  as  the 
patient  got  the  mercury  to  rise  so  high  he  saw  no  rea- 
son why  she  should  not  succeed  in  getting  it  to  rise 
eren  higher,  and  as  the  ordinary  clinical  thermometer 
was  not  long  enough,  he  used  a  stove  thermometer 
oaddng  as  high  as  160^  Centigrade,  and  to  his  great 
confosiDn,  and  that  of  his  assistants,  this  thermometer, 
«lnch  was  placed  in  the  axilla,  one  morning  marked  76°, 
vhidi  a  few  days  later  was  even  surpassed.  The  trickery 
vas,  however,  at  last  found  out.  When  the  patient 
tiiooght  she  was  not  observed,  she  was  seen  approaching 
Ikerleft  hand  to  the  lower  extremity  of  the  thermometer 
^^uch  was  placed  in  the  right  axilla,  and  finally  the 
n»ystery  was  discovered.  The  interne,  who  was  on  the 
vatch,  demonstrated  that  by  gently  and  repeatedly  strik- 
ing the  lower  extremity  of  the  thermometer,  the  mercury 
coold  be  made  to  rise  to  any  height  in  the  instrument. 
Dr.  Du  Castel,  who   communicated   this  case   to  the 


Medical  Society,  said  he  merely  wished  to  observe  of 
how  little  use  it  was  to  take  the  temperature  in  hysteri- 
cal patients  unless  they  were  closely  watched. 

Dr.  Hanriot  Agr^gd  has  been  appointed  Professor  of 
Chemistry  at  the  Paris  Faculty  of  Medicine,  in  the  room 
of  Professor  Wurtz,  lately  deceased. 


^vtm  atifi  W^vv^  ^jeujs. 


Official  Listof  Changes  in  the  Staiians  a$id  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army, 
from  June  29  to  July  5,  1884. 

GiRARD,  J.  B.,  Captain  and  Assistant  Surgeon.  Or- 
dered to  relieve  Surgeon  W.  E.  Waters  from  duty  as 
Post  Surgeon,  Plattsburg  Barracks,  Plattsburg,  N.  Y. 
Surgeon  Waters,  upon  being  relieved,  directed  to  return 
to  his  proper  station  (Madison  Barracks,  N.  Y.).  S.  O. 
131,  par.  3,  Headquarters  Department  of  the  East,  June 
30,  1884. 

Hartsuff,  Albert,  Major  and  Surgeon  (Fort  Riley, 
Kan.).  Granted  leave  of  absence  for  one  month,  with 
permission  to  apply  for  one  month's  extension.  To  take 
effect  when  his  service  can  be  spared  S.  O.  130,  par.  6, 
Headquarters  Department  of  Missouri,  June  25,  1884. 

MiDDLETON,  J.  V.  D.,  Major  and  Surgeon.  Ordered 
to  relieve  Surgeon  B.  E.  Fryer  from  duty  as  Post  Sur- 
geon, Fort  Leavenworth,  Kan.,  on  or  before  July  ist. 
S.  O.  133,  par.  5,  Headquarters  Department  of  Mis- 
souri, June  28,  1884. 

Benham,  R.  B.,  First  Lieutenant  and  Assistant  Sur- 
geon. From  Department  of  Dakota  to  Department  of 
Texas.     S.  O.  150,  par.  8,  A.  G.  O.,  June  28,  1884. 

GoRGAS,  William  C,  First  Lieutenant  and  Assistant 
Surgeon.  From  Department  of  Texas  to  Department 
of  Dakota.     S.  O.  150,  par.  8,  A,  G.  O.,  June  28,  1884. 

Wales,  Philip  G.,  First  Lieutenant  and  Assistant 
Surgeon.  From  Old  Fort  Colville,  Washington  Terri- 
tory to  Fort  Coeur  d'Alene,  Idaho.  S.  O.  89,  par.  3, 
Headquarters  Department  of  Columbia,  June  23,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy,  during  the  week  ending  July  5,  1884. 

Wells,  H.  M.,  Surgeon.     Detached  from  Naval  Hos- 
pital, Brooklyn,  ordered  to  U.  S.  S.  Lancaster. 

Sayrs,  J.  S.,  appointed  Assistant  Surgeon.     Commis- 
sion dated  June  27,  1884. 

Cordeiro,  F.  J.   B.,   appointed   Assistant  Surgeon. 
Commission  dated  June  27,  1884. 


Prevention  of  Cholera. 

[1884.    Department  No.  98.    Marine  Hospital  Service.] 

Treasury  Department, 

Office  of  the  Secretary, 
Washington,  D.  C,  July  2,  1884. 
To  Collectors  of  Customs: 

It  has  been  brought  to  the  attention  of  the  Depart- 
ment that  persons  from  the  infected  districts  of  France 
are  leaving  in  considerable  numbers  by  other  than 
French  lines.  You  will,  therefore,  require  evidence  that 
none  of  the  baggage  of  immigrants  or  returning  travellers 
has  been  shipped  from  the  infected  districts  since  June 
20,  1884.  A  certificate  of  the  local  quarantine  officer 
to  the  effect  that  no  danger  to  the  public  health  need  be 
apprehended  from  allowing  the  landing  of  any  passen- 
ger's baggage,  may  be  accepted  as  entitling  such  traveller 
or  immigrant  to  land  his  effects. 

ChAS.  J.  FOLGER, 

Secretary. 


56 


THE  MEDICAL  RECORD. 


[July  12,  1884- 


ptedical  Stems. 


Contagious  Diseases — Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  July  5,  1884 : 


Week  Ending 


Casts. 
June  28, 1884.. 
Julys,  1884... 

Diaths^ 
June  28,  1884.. 
Julys,  1884... 


186 
156 


The  Significance  of  Scars  and  Copper-Colored 
Spots  on  the  Forehead. — T.  Pershing,  of  Wilmington, 
Del.,  criticises  a  statement  made  by  Dr.  A.  L.  Ranney  in 
the  first  of  his  articles  on  "  Methods  of  Examination  in 
the  Diagnosis  of  Nervous  Diseases,'*  published  in  The 
Record.  It  is  there  affirmed  that  ulcerations  upon  the 
forehead  not  traumatic  are  syphilitic ;  scars  and  copper- 
colored  spots  are  equally  significant.  Dr.  Pershing  says 
that  "herpes  zoster  occurring  on  the  forehead  may  be 
severe  enough  to  cause  ulcerations.*  * 

The  Treatment  of  Asphyxia. — A  lecture  was  re- 
cently delivered  by  Dr.  Benjamin  Howard,  in  the  course 
of  Professor  Charcot,  at  the  Salp6tri^re,  upon  the 
mechanism  and  treatment  of  asphyxia.  The  plan  usually 
followed,  of  making  traction  upon  the  tongue,  is,  the 
lecturer  stated,  useless,  for  the  anatomical  conditions  will 
not  admit  of  elevation  of  the  epiglottis  by  this  means. 
The  only  way  by  which  this  elevation  can  be  accom- 
plished is  to  place  the  head  and  neck  in  a  position  ot 
forced  extension.  When  this  is  done,  the  tongue  is  sepa- 
rated from  the  pharynx  and  a  wide  and  free  passage 
without  any  obstruction  is  established  leading  directly 
from  the  posterior  nares  to  the  lungs.  The  lecture  was 
supplemented  by  demonstrations  upon  the  cadaver  in 
which  the  facts  were  proven  to  be  as  stated. 

Dermatology  at  Vienna. — A  correspondent  of  the 
Northwestern  Lancet  writes  :  "  One  very  noticeable  feat- 
ure is  the  almost  exclusively  local  treatment  of  all  skin 
diseases,  except  those  due  to  syphilis,  and  the  scrofulous 
or  tuberculous  diathesis.  Though  Kaposi  mentions  iron 
and  arsenic  in  his  book,  I  never  saw  it  given  or  men- 
tioned in  the  hospital.  Scrofulous  and  chlorotic  patients 
were  given  cod-liver  oil,  which  was  almost  the  only  in- 
ternal medication  which  I  observed.  He  says  the  inter- 
nal treatment  of  skin  diseases  was  proven  useless  years 
ago  in  this  hospital.  He  is  accustomed  also  to  occasion- 
ally express  himself  very  strongly  upon  the  doctrine  that 
tubercle,  lupus,  and  syphilis  are  related  diseases.  He,  as 
well  as  Neumann,  repudiates  this  idea  in  toto.  On  every 
reference  to  the  subject  he  says :  *  Gentlemen,  lupus  is 
lupus,  tubercle  is  tubercle,  and  syphilis  is  syphilis.  Any 
shading  of  the  one  into  the  other  does  not  exist.  Syphi- 
litic lupus  is  nonsense.'  Lately  he  read  that  Koch 
claims  to  have  discovered  the  tubercle  bacillus  in  lupus 
nodules.  He  said  on  coming  to  the  class :  *  Gentlemen, 
if  this  be  so,  all  I  have  to  say  is  that  it  is  bad  for  the 
bacillus,  for  it  would  be  proof  positive  that  he  is  not  the 
cause  of  specific  tuberculosis.'  The  favorite  treatment  of 
lupus  is  removal  of  the  nodules  with  the  caustic  potash 
stick  or  a  curette,  and  application  of  mercurial  plaster. 
During  the  winter  he  used  the  treatment  of  the  sublimate 
solution.     It  bleached  the  ugly-looking  surfaces,  remov- 


ing the  coloring  matter  from  the  scars  very  nicely,  but 
caused  so  much  eczema,  and  the  apparent  benefit  was  so 
transient  that  it  was  soon  thrown  aside.  Psoriasis,  when 
not  covering  too  great  an  area  of  skin,  is  treated  by  re- 
moving the  scales  with  a  curette,  or,  after  maceration 
with  soft  soap,  removal  in  the  bath  with  a  scrubbing 
brushy  after  which  the  affected  partsof  the  skin  are  painted 
with  chrysarobin  salve — chrysarobin  5  or  10  to  vaseline 
40 — twice  a  day  for  several  days.  Every  one  of  the 
large  number  of  cases  which  I  observed  improved  rapidly. 
Owing  to  the  discoloration  of  the  skin  caused  by  chrysaro- 
bin, the  face,  head,  and  hands  are  never  treated  wifli  this 
remedy.  On  these  parts  tar  is  still  the  favorite.  A  pyro- 
gallic  acid  salve  of  the  same  strength  is  sometimes  used, 
spread  upon  linen,  and  after  removing  the  scales  as  be- 
fore. It  does  not  cure  so  rapidly  as  the  chrysarobin,  but 
in  skins  which  would  be  too  severely  inflamed  by  the  lat- 
ter drug  it  proves  very  useful." 

The   Treatment   of    Tape-Worm  —  Tape-Worms 
AND  Pregnancy. — Dr.  Frank  H.  Rowe,  of  Cummins- 
ville,  O.,  referring  to  a  request  for  opinions  regarding 
the  treatment  of  tape-worm,  sends  the  following.    The 
ingredients  must  be  reliable  and  the  compounding  care- 
fully done  :    "  5 .  Pulv.  cort.  radix  ^ranat.,  \  ss. ;  pulv. 
secale  cornut,  3  ss. ;  pulv.  gum  acacia,  3  ij- ;  ol.  felicis, 
3j.,  ol.  crotonis,  one  drop,  mixed  well;   mix  well  in 
rotation,  pulv.  peponis,  |j.     M.    Ft.  emulsio  with  aq. 
dest.,  S  vij.,  add  sodje  salicylate,  grs,.xv.     S.   Take  the 
above  emulsion  at  once  in  the  morning.     One  hour  be- 
fore taking  it,  take  a  small  cup  of  good  coffee  alone ;  the 
emulsion  should  be  taken  while  lying  down,  a  sinapism 
of  pure  mustard  having  been  previously  applied  over  the 
epigastrium.     After  the  free  use  of  saline  cathartics,  sol- 
magnes.  cit.,  5  ^ij.,  magnes.  sulph.,   f  j.     M.  S.  at  once 
— to  be  taken  the  previous  day.     And  the  evening  be- 
fore taking  the  emulsion,  the  supper  should  consist  of  a 
very  liberal  repast,  consisting  exclusively  of  onions  and 
herring  (or  mackerel)  salad.     While  referring  to  the  sub- 
ject of  tape-worm,  I  would  notice  a  recent  article  in  the 
London  Record  in  relation  to  the  reflex  disturbances  pro- 
duced by  taenia,  ascribing  a  series  of  miscarriages  in  one 
or  two  individuals  to  their  presence,  pregnancy  going  on 
to  full  time  after  the  removal  of  the  worm.     Such  has 
not  been  my  experience  in  a  recent  case  of  a  similar 
character.     A  patient  having  had  at  least  four  miscar- 
riages between  the  fifth  and  seventh  month,  accidentally 
discovered  evidences  of  the  presence  of  a  tape-worm.     I 
successfully  treated  her  for  it  in  the  meantime.     She  be- 
came pregnant,  and  flattered  herself  that  the  cause  of 
her  miscarriages  was  removed,  and  that  she  would  go  on 
to  full  time.     Such,  however,  was  not  the  case,  as  at  the 
usual  time  she  miscarried.     Habit  possibly  had  some  in- 
fluence in  determining  this.     The  reflex   disturbances 
produced  by  taenia  seem  to  be  over-estimated.     And, 
judging  from  the  physical  condition  of  cases  seen,  one 
must  conclude  that  their  effect  upon  the  health  of  the 
individual  containing  them  must  oftentimes  be  almost 

nur 

Antipyrin  is  the  name  of  a  chinolin-derivative'^  first 
used  by  Filehne  and  recently  experimented  with  by  P. 
Guttmann.  In  doses  of  two  grammes  it  reduces  the  tem- 
perature powerfully,  this  reduction  lasting  five  to  sLx 
hours.  It  has  no  bad  after-effects,  and  only  very  rarely 
disturbs  the  stomach. 

A  Novel  Method  of  Cultivating  Bacilli. — Prof. 
Baumgarten  takes  a  bit  of  tuberculous  tissue  and  intro- 
duces it  with  antiseptic  precautions  into  the  anterior 
chamber  of  a  rabbit's  eye.  After  six  or  eight  days  he  re- 
moves a  small  portion  of  the  tuberculous  nodule  and 
introduces  it  into  a  second  rabbit's  eye,  and  in  six  to 
eight  days  repeats  the  process  with  a  third  rabbit.  He 
thus  gets  a  mass  of  tubercle  bacilli  almost  entirely  free 
from  extraneous  tissue.  He  recommends  this  method  a^ 
the  most  convenient  and  certain  way  of  securing  pure 
cultivations. 


The   Medical   Record 

A   Weekly  Journal  of  Medicine  and  Surgery 


Vol.  a6.  No.  3 


New  York,  July  19,  1884 


Whole  No.  7x5 


<3^ri0itial  ^rticljea 


SOME  REMARKS  ON   AFFECTIONS  OF    THE 
HEART. 

By  J.  MILNER  FOTH£RGILL,  M.D.  Edin.,   Hon.    M.D. 

Rush  Mkd.  Coll.,  III. 
isnokrft  FBLLovr  op  thr  collbgb  or  physicians  op  philadblfhia,  physician 

TO  THE  CITY  OP  IjOKDON  HOSPITAL  POR  XMSBASBS  OP  THE  CHBST. 
III. 

STRUCTURAL  CHANGES. 

Probably  there  is  no  disease  to  which  humanity  is  liable 
more  dreaded  than  fatty  degeneration  of  the  heart.  All 
stndents  are  liable  to  have  this  weird  malady,  wrapt  in 
ffl/stexy,  when  first  studying  disease  of  the  heart ;  it  is 
the  k^  noir  oi  many  persons  who  curiously  dip  into 
medical  literature,  especially  if  their  thoughts  are  directed 
bf  their  family  history  to  cardiac  maladies ;  perhaps 
medical  men  themselves  fear  it  more  than  any  occult 
malady  with  the  exception  of  aneurism.  Why  is  all  this? 
fiecsuise  it  is  a  general  belief  that  fatty  degeneration  of 
die  heart  is  a  disease  which  is  shrouded  from  our  ken ; 
k  stalks  in  darkness,  unseen,  beyond  detection.  Mys- 
teiy  ^ves  it  its  terrors ;  it  belongs  to  the  unknown ! 
N'odimg  of  the  kind !  It  is  a  malady,  which  reveals  itself, 
albeit  not  one  which  forces  itself  upon  the  attention  like 
nlrular  disease,  or  a  paralyzed  limb.  Fatty  degenera- 
tion  of  the  heart  has  its  known  history,  its  pathological 
idations,  like  other  diseases.  That  it  is  the  cause  of 
sodden  death  may  at  once  be  laid  down  as  an  axiom.  So 
long  as  its  structure  is  unimpaired,  its  muscular  fibrillar 
sound,  the  heart  will  struggle  on,  often  though  the  cause 
of  death,  yet  itself  the  last  to  die. 

Fatty  decay  of  the  heart-wall  may  go  on  masked  by 
odier  troubles,  and,  consequently,  not  be  recofpized,  as 
occnnred  in  a  padent  of  mine  at  the  hospital  while  writing 
tbese  papers.  She  was  a  woman  in  the  fifties,  with  some 
sdema  in  her  legs,  and  a  mitral  lesion  ;  not,  apparently,  a 
foj  serious  case.  She  stood  a  full  dose  of  compound  jadap 
powder  without  any  suspicious  indications,  and  seemed  to 
be  improving,  when  suddenly  she  died  without  a  struggle, 
^fben  the  post-mortem  came  the  explanation  was  not  &r 
loseeL  She  had  a  nutmeg  liver,  granular  kidneys,  and 
Stature  of  the  heart- wall  was  considerably  impaired. 

Sbebdbeen,  in  all  probability,  a  drunkard.  But  of  this 
itBapossible  to  be  certain.  A  faint  arcus  senilis  and  a 
cMf  cornea  was  the  only  outward  visible  sign  of  the 
mid  pathological  changes.  Here  fatty  degeneration 
■^  have  been  suspected,  but  it  was  certainly  not 
liable.  There  was  no  clot  in  the  heart :  death  had 
coBie  about  by  fatal  syncope.  And  it  is  this  last  to 
vbdi  imy  degeneration  renders  its  victim  liable ;  no 
■ttter  whether  the  appearance  of  general  health  is  main* 
liBed,  or,  as  in  the  case  just  given,  there  is  also  other 
fdpabie  disease  present. 

At  other  times  an  elderly  man  dies  suddenly  after  an 
Ad,  as  rushing  to  catch  a  train ;  or  after  emotion,  like  the 
fat  anatomist  John  Hunter :  or  at  some  gathering ;  or 
tttlie  nii^t-stool,  as  died  a  well-known  temperance  lec- 
^■cr  under  my  own  care  not  long  ago.  In  the  last  case  a 
hie,  veO-nounshed,  florid,  elderly  man,  who  had  quite  re- 
^ndf  been  lecturing  with  his  wonted  vigor,  was  seized  with 
jftattack  of  severe  dyspnoea,  which  left  him  shaken,  but  not 
*lltt«ise  the  worse  of  it  His  medical  attendant  called 
^  in  in  consultation,  and  the  circumstances  roused  my 


suspicions  that  the  right  ventricle  was  not  to  be  trusted. 
Strict  orders  were  given  about  quiet  being  maintained, 
all  effort  avoided,  especially  straining  at  stool  (which 
brought  on  the  attack),  and  no  lectures  to  be  announced 
for  some  time.  All  went  well  for  a  time,  and  he  began 
to  think  the  doctors  took  too  grave  a  view  of  his  case. 
So  he  went  down  to  the  city  to  see  to  some  business, 
came  home,  after  that  went  into  the  water-closet,  and  died 
there.  There  is  no  moral  doubt  that  there  was  fatty 
decay  of  the  right  ventricle  present  in  that  case. 

What  are  the  indications  of  a  fatty  decay  in  the  heart- 
walls  ?  The  heart  has  a  dead-leaf  here  instead  of  the 
normal  dark  flesh  color,  i,e,,  when  the  condition  is  pro- 
nounced ;  it  is  friable,  readily  torn,  and  if  a  piece  be 
pressed  between  'blotting-paper  the  stain  of  grease  is 
found.  Under  the  microscope,  first,  the  transverse  striae 
are  clouded  and  then  lost ;  second,  granules  of  fat  are  to 
be  seen  near  the  germinal  matter,  afterward  spreading 
throughout  the  fibril ;  third,  the  fibril  has  given  way  to  a 
string  of  oil  globules  within  the  sarcolemma.  The  disease 
may  be  general ;  it  may  be  connected  with  the  area  sup- 
plied by  one  coronary  artery ;  or  it  may  belong  only  to 
the  area  fed  by  one  branch  of  one  of  die  coronary  arte- 
ries, where  that  branch  is  occluded  by  some  growth  in 
the  wall  of  the  vessel 

What  is  the  cause  of  decay  in  the  fibrillar  of  the  heart* 
wall?  An  insufficient  supply  of  blood.  How  is  that 
brought  about  ?  By  an  atheromatous  condition  of  the 
tunica  intima  of  the  nutrient  artery  usually.  Degenera* 
tive  change  in  the  coronary  vessels  is  the  cause,  par  ex* 
celUnce^  of  fatty  necrosis  of  the  muscular  fibrillse  of  the 
heart.  There  may  be  an  atheromatous  tubercle  blocking 
the  orifice  of  a  coronary  artery,  as  was  found  in  an 
elderly  gentleman  who  died  in  the  sexual  act  with  a 
venal  Venus,  in  one  of  our  London  parks,  some  time  ago. 
Or  it  may  be  that  an  adherent  pericardium  along  the 
coronary  vessels  cuts  down  the  blood-supply  until  the 
heart-fibre  is  no  longer  properly  nourished,  as  was  said 
to  be  the  case  with  the  late  renowned  Sir  James  Young 
Simpson.  But,  speaking  broadly,  when  fatty  degenera- 
tion of  the  heart-wall  is  found,  the  coronary  arteries  are 
the  seat  of  atheromatous  change.  Atheroma  is  the  de- 
velopment of  connective  corpuscles  in  or  under  the 
tunica  intima  of  the  arterial  wall.  It  may  be  in  patches 
or  it  may  be  diflused.  Usually  there  is  the  hard  artery, 
liable  to  be  also  tortuous.  The  change  can  often  be 
seen  in  the  temporal  arteries,  which  to  the  eye  elon|;ate 
on  each  pulse-beat.  The  artery  loses  its  elasticity 
while  its  lumen  is  diminished. 

The  general  associations  of  the  fatty  heart  are  these : 
First,  the  «* gouty  heart,"  or  chronic  Bright's  disease,  a  large 
left  ventricle,  a  tight  artery,  and  an  accentuated  second 
sound  at  the  aortic  root  The  physiological  evidence  of 
high  arterial  tension  is  a  large  bulk  of  urine.  But  after  a 
time  the  bulk  of  urine  drops ;  and  as  Sir  William  Jenner  has 
pointed  out,  this  is  a  clinicsd  fiict  of  the  grimmest  signifi- 
cance. Why  is  the  bulk  of  urine  falling  ?  Because  the 
hypertrophied  heart-wall  is  being  undermined  by  a  decay 
in  the  muscular  fibrillar.  There  are  other  evidences  of  a 
waning  energy  in  the  left  ventricle,  and  the  case  either 
ends  suddenly,  or  presents  the  well-known  features  of 
heart-failure.  Sometimes  there  is  little  hypertrophy,  and 
diese  are,  apparently,  the  cases  where  death  takes  place 
suddenly,  on  or  after  some  effort,  as  a  rule.  Old  people 
are  intensely  reticent  when  they  have  done  something 
foolish,  and  if  all  the  circumstances  could  be  known,  my 


58 


THE  MEDICAL  RECORD. 


[July  19. 1884- 


own  utdividual  opinion  is  that  a  history  of  some  effort 
would  be  found  to  precede  the  fatal  syncope  in  almost 
ail  cases  where  the  heart  ceases  suddenly  in  diastole  in 
persons  apparently  well.  In  some  cases  the  fatal  event 
occurs  in  a  person  apparently  in  fair  health,  as  in  the 
case  given  of  the  temperance  lecturer.  At  other  times 
evidences  have  been  furnished  of  failure  of  the  heart  un- 
mistakably pointing  to  the  morbid  change.  At  other 
times  men  are  seen  with  a  tranquil  gait,  very  careful  of 
themselves,  apt  to  have  attacks  of  vertigo,  are  seen  at 
times  to  clutch  at  some  object  to  help  them  to  keep  up, 
who  are  said  to  be  the  subjects  of  fatty  degeneration  of 
the  heart — and  doubtless  in  some  cases  this  is  correct. 
At  other  times  such  is  not  the  case.  I  remember  when 
in  general  practice  being  called  in  to  see  an  old  gentle^ 
man,  who  from  his  evidences  of  failing  strength,  plus  the 
feebleness  of  his  heart-sounds  and  the  condition  of  his 
arteries,  was  to  all  appearance  the  subject  of  a  fatty 
heart.  Yet  by  rest  and  tonics  in  time  he  improved 
greatly,  and  as  the  heart  regained  its  tone  an  aortic 
systohc  murmur  could  be  heard  while  there  were  evi- 
dences of  hypertrophy  of  the  left  ventricle.  When  I  left 
the  neighborhood  he  was  a  hale,  fairly  active  old  man, 
and  died  of  something  unconnected  with  his  heart.  It  is 
quite  clear  that  this  case  was  not  one'  of  fatty  degenera- 
tion of  the  hearty  but  rather  one  of  temporary  malnatxi- 
tion. 

How  is  it  that  very  often  the  morbid  condition  of 
atheromatous  change  is  more  pronounced  in  the  coronary 
arteries  than  in  any  other  part  or  portion  of  the  arteriid 
system  ?  Such  is  undoubtedly  the  fact,  and  the  thick- 
ened, tortuous,  white  coronary  arteries  stand  out  prom- 
inently by  contrast  with  the  blue  veins  when  the  heart  is 
laid  bare.  They  are  thickened,  and  what  is  more^  their 
calibre,is  diminished,  and  with  that  the  blood-current  which 
flows  through  them.  The  heart-muscle  is  underfed,  and 
then,  in  time,  fatty  degeneration  of  the  fibrilke  follows. 
Why  is  the  coronary  circulation  so  much  more  than  any 
other  part  of  the  arterial  system  the  seat  of  this  morbid 
process  ?  To  my  mind,  the  answer  is,  that  this  is  due 
to  the  fact  that  the  coronary  arteries  spring  from  the 
aortic  root  and  so  are  filled  by  the  full  force  of  the  aortic 
recoil.  Other  arteries  of  like  size  have  the  shock  broken 
by  intervening  moderate-sized  vessels,  or  are  not  so 
forcibly  dilated  by  the  aortic  recoil.  The  full  force  of 
the  aortic  recoil  falls  upon  the  aortic  valves,  and  the 
blood-current  eddies  furiously  in  the  sinuses  of  Valsalva, 
acutely  distending  the  coronary  arteries.  Especially 
is  this  the  case  with  the  hypertrophied  ventricle  and 
high  arterial  tension  of  the  gouty  heart.  Atheroma  is 
the  result  of  over-distention  {ueberspannung)  plus  some 
tissue-tendencies  of  the  gouty  diathesis,  or  the  syphilitic 
cachexia.  Consequently,  while  the  aorta  and  the  rest  of 
the  arterial  system  are  but  in  an  early  stage  of  the  athero- 
matous change,  and  still  possess  considerable  elasticity, 
the  coronary  arteries  are  in  an  advanced  condition,  are 
tortuous,  inelastic,  with  their  calibre  gravely  diminished 
by  thickening  of  the  tunica  intima  encroaching  on  the  bore 
of  the  blood-vessel.  The  lessened  blood-current  is 
broken  in  its  course  by  the  curves  of  the  artery  and  an 
insufficient  blood-supply  to  the  heart-muscle  leads  to  its 
decay.     Such  is,  to  my  mind,  the  sequence  of  the  events. 

Consequently  fatty  degeneration  is  the  sequel  to  the 
gouty  heart  Such  at  least  are  its  clinical  phenomena 
as  presented  to  me  in  my  experience.  Of  course  a  man 
must  be  guided  by  what  he  himself  has  seen  and  en- 
countered ;  he  cannot  be  so  familiar  with  the  experience 
of  others,  but  what  I  read  of  their  observations  tallies 
with  my  own.  As  an  apple  waxes,  ripens,  and  ultimately 
rots,  so  the  gouty  heart  passes  through  these  varying 
phases  of  muscular  growth,  high  arterial  tension,  harden- 
ing arteries,  and  diminution  of  calibre  by  the  atheromat- 
ous change,  the  blood-supply  to  the  cardiac  muscle 
being  cut  down  until  the  muscle  is  unequal  to  its  work, 
and  stops  in  diastole.  Having  run  the  risks  of  the  heart 
bursting  the  arteries,  the  big  heart  gradually  rots  and 


'8top3.  Haying  passed  the  rocks  of  the  earlier  risks  the 
patient  drifts  on  to  the  deadlier  shallow  beyond.  The 
history  of  many  families,  certainly  my  own  on  all.  sides, 
is  arterial  rupture  (which  in  no  case  has  been  fatal,  and 
that  only  in  advanced  life),  followed  in  time  by  sudden 
cessation  of  the  heart  in  diastole  from  softening  of  its 
fibres ;  and  this  last  morbid  change  has  always  given  dis- 
tinct evidence  of  its  approach  and  not  come  like  a  thief 
in  the  night 

Such,  then,  is  my  view  of  the  natural  history  of  the 
fatt^  heart :  it  is  the  last  development  of  a  long  patho- 
logical process,  the  longest  and  most  striking  wiSi  which 
we  are  yet  familiar 

Of  course  it  is  not  asserted  that  fatty  degeneration  of 
the  heart  never  has  any  other  antecedents ;  but  this  is 
its  history  as  ordinarily  encountered  in  practice.  Occlu- 
sion of  the  coronary  arteries,  or  rather  partial  occlusion, 
is  the  cause  of  the  decay  of  the  heart-walL  In  one  case 
death  may  take  place  suddenly,  unexpectedly.  In  an^ 
other,  and  far  more  commonly,  when  the  wall  is  weakened 
dilatation  commences,  or  rather  recommences,  and  as 
hypertrophy's  arresting  hand  is  lifted  so  the  symptoms 
of  a  failing  heart  are  developed,  and  all  the  skill  and 
pains  in  the  world  can  never  strengthen  that  failing 
heart,  or  even  do  much  to  stave  off  the  inevitable  end. 
When  a  patient  with  an  hypertrophied  heart  and  hard 
arteries  begins  to  And  the  bulk  of  urine  falling,  and  then 
heart  symptoms  showing  themselves,  with  or  without  any 
coexistent  valvular  disease,  the  transient  eye  can  read 
the  beginning  of  the  end.  And  this  end  is  far,  far  more 
common  than  sudden  death  in  the  midst  of  apparent 
health,  where  the  heart  has  undergone  little  or  no  pre* 
ceding  enlargement. 

Fatty  degeneration  of  the  heart  is  common  with  ill-fed 
drunkards.  But  it  has  nothing  to  do  with  obesity,  and 
is  as  comnon  in  lean  persons  as  with  stout  persons.  It 
has  no  relation  to  the  growth  of  adipose  tissue.  It  is 
a  decay  of  the  muscular  flbrillae,  which  undergo  in  life 
the  same  molecular  changes  as  are  found  in  the  produc- 
tion of  adipocere  after  death.  Fat  takes  the  place  of 
muscular  tissue  within  the  scarcolemma,  and  the  heart 
stops  contracting  because  it  is  the  seat  of  mural  decay, 
in  other  words  is  "  rotten." 

A  species  of  acute  fatty  degeneration  of  the  heart  goes 
on  whenever  a  high  temperature  is  maintained  for  some 
time,  as  in  the  specific  fevers.  Indeed,  in  relapsing  fever, 
where  the  temperature  runs  very  high,  the  heart  becomes 
so  weakened  that  death  from  syncope  is  not  rare  in  the 
stage  of  convalescence. 

The  rebuilding  of  the  cardiac  fibrillar  ai^er  a  sharp 
pyrexia  is  sometimes  very  slow,  and  months  may  elapse 
before  the  patient  is  equal  to  much  exertion.  The  most 
pronounced  cases,  in  my  experience,  of  cardiac  adynamia 
due  to  acute  fatty  degeneration  have  been  those  of  young 
adults  who  have  had  typhoid  fever,  several  of  them  medi- 
cal men. 

Then  there  is  fatty  infiltration,  a  growth  of  true  adipose 
tissue  outside  the  heart  and  to  some  extent  within  its 
structure.  Here  fat  is  deposited  betwixt  the  fibrillse, 
which  are  pressed  upon  by  these  fet-cells.  A  certain 
amount  of  adynamia  in  the  heart  is  the  result  Such 
fatty  growth  is  usually  found  in  obese  persons  of  lax  fibre. 
It  is  by  comparison  with  fatty  degeneration  a  somewhat 
uninteresting  pathological  condition. 

Then  there  is  a  condition  of  adynamia  in  the  heart,  and 
also  in  the  diaphragm,  which,  in  its  features,  simulates 
fatty  degeneration  m  conditions  where  the  assimilation 
of  albuminoids  is  impaired.  It  is  commonly  seen  where 
the  liver  is  disturbed,  and  instead  of  elaborating  the  pro- 
teids  brought  to  it  by  the  portal  vein  ^or  perhaps  peptones 
not  converted  once  more  into  proteids)  into  the  serum- 
albumin  of  the  liquor  sanguinis,  the  liver  turns  them 
into  lithates  and  bile  acids,  in  consequence  of  which  the 
heart  and  diaphragm  are  ill-nourished.  Being  ill-nour- 
ished they  are  deprived  of  much  of  their  energy,  with  the 
result  that  the  pulse  is  feeble,  the  heart-sounds  weak, 


July  i9>  1884.J 


THE  MEDICAL  RECORD. 


59 


there  is  cerebral  ansemia,  there  is  breathlessness  in  effort 
(partly  from  feebleness  in  the  diaphragm),  and  the  gen- 
^  condition  which  is  associated  with  fatty  degeneration 
is  closely  simulated.  Indeed  it  is  the  "double  "  of  fatty 
degeneration.  To  this  state  I  have  given  the  name  of 
** Heart  Starvation,"  for  which  a  critic  in  the  London 
Medical  Record  accused  me  of  "  the  attempt  to  dress  up 
well-known  clinical  facts  in  strange  and  startling  phrase- 
ology;*' continuing:  "Apart  from  the  language  in  which 
they  are  disguised,  there  is  not  a  fact  mentioned  in  this 
essay  which  is  not  also  a  commonplace  to  every  expe^ 
rienced  practitioner  "  (August,  1881).  Despite  this  hare- 
brained frivol  of  self-satisfied  ignorance,  many  men 
of  sound  judgment  regard  the  essay  as  a  useful  contri- 
bution to  medicine  on  a  subject  on  which  little  is 
known.  If  this  occurs  in  a  comparatively  young  person 
it  would  hardly  be  likely  to  be  mistaken  for  a  truly  senile 
change.  But  when  it  occurs  in  a  person  who  is  of  that 
age  when  senile  changes  may  be  looked  for,  it  is  not 
always  possible  to  distinguish  betwixt  it  and  fatty  degene- 
ration of  the  heart,  as  in  the  case  given  above  as  occur- 
ring in  my  early  days.  It  is  really  this  condition  of  mal- 
nutrition grafted  upon  an  old-standing  valvular  lesion 
which  brin^  the  patient  to  the  doctor  very  often.  For- 
tunately it  is  a  remediable  condition,  which  fatty  degene- 
ration (as  described  above)  certainly  is  not: 

The  condition  of  the  heart-muscle  is  a  matter  on  which 
more  general  information  is  desirable.  It  is  not  fiatter- 
mg  to  our  profession  to  hear  patients  say  that  years 
before  they  had  been  told  they  had  fatty  degeneration  of 
the  heart  and  must  soon  die  suddenly,  and  yet  then  were 
well  The  condition  which  had  been  diagnosed  as  "  fatty 
degeneration  "  was  really  that  of  its  double,  "  heart  star- 
ration." 


A  CONTRIBUTION  TO  THE  STUDY  OF  CO- 
RYZA  VASOMOTORIA  PERIODICA,  OR  SO- 
CALLED  «  HAY  FEVER.'*  * 

By  JOHN  N.  MACKENZIE,  M.D., 

BKVRi   TO    TM«     BAI.TIMOKB    BYK,     BAR,    AND    THSOAT  .CMARTTY     HOSMTAL, 
BALTIMOKB,  MD. 

^^Nunqu€im  ita  fuisquam  bene  subducta  raiione  ad  vitam  fuity 
QuiH  res,  atas,  usus  semper  aliquid  opportet  novi^ 
AUqmd  moneat,  ut  ilia  qua  te  scire  credos,  nescias^ 
Ety  qua  tibi  putaris  prima^  in  experiundo  ut  repudies?'* 

—Terence,  in  "  Adelphis,"  Act  V. 

When  the  phenomena  of  a  given  disease  or  unnatural 
condition  are  inexplicable  by  known  pathological  laws,  or 
do  not  come  within  the  range  of  that  specidation  which 
onpirical  fact  and  scientific  experiment  allow,  it  is  cus- 
tOBoary  to  seek  in  the  term  "  idiosyncrasy  "  a  convenient 
icfage  for  acknowledged  ignorance.     This  applies  with 
especial  force  to  the  affection  in  question,  the  peculiar 
fetoes  of  whose  clinical  history  have  been  submitted  to 
til  lazy  explanation.     The  well-recognized,  but  imper- 
fady  andeistood  personal  susceptibility  to  certain  forms 
of  local  irritation,  which  is  the  sad  prerogative  of  the 
afeers  from  this  disease,  has  always  been  the  stumbling- 
Nock  in  its  investigation  and  the  rock  upon  which  the 
niioQs  speculations  as  to  its  nature  have  been  wrecked. 
Hasty  generalizations  based  on  the  study  of  conditions 
«tternal  to  the  organism,  to  the  exclusion  of  pathological 
Vncies  within,  together  with  deductions  drawn  from  iso- 
«ed  cases,  and  the  uncertain  testimony  of  the  laity,  have 
t^  rise  to  a  variety  of  names  indicative  of  its  supposed 
rt^)gy,  such  as  "hay  fever"  or   "asthma,"  "pollen 
TO"  or  "poisoning,"  "rose"  or  "peach  cold,"  etc, 
appellations  which  should  be  discarded  and  forgotten,  as 
]key  not  only  tend  to  perpetuate  erroneous  views  and  to 
J^uce  elements  of  confusion  into  the  investigation, 
wt  also,  by  a  diversion  of  the  mind  from  mere  essential 
Woditions,  have  in  no  small  measure  contributed  to  retajrd 
^ogress  in  the  therapeutic  management  of  the  disease. 

jjJlaaarB  ddivcred  at  the  Baltunore  Eye,  Ear,  and  Throat  Hospital.  June  14, 


While  the  term  coryza  vasomotoria  periodica^  suggested 
in  the  title  of  this  communication,  does  not  meet  all  the 
requirements  of  a  logical  definition,  it  may  nevertheless 
be  used  provisionally  until  more  exact  knowledge  of  the 
affection  furnishes  data  for  the  construction  of  a  better. 
For,  as  will  be  shown  below,  the  disease  is  essentially  a 
coryza,  showing,  in  most  cases,  a  decided  tendency  to 
periodic  recurrence,  and  dependent  upon  some  functional 
derangement  of  the  nerve-centres  as  its  predisposing 
cause. 

Until  within  the  past  few  years  clinical  and  experi- 
mental inquiry  has  been  directed  to  the  investigation  of 
the  most  prominent  exciting  external  influences  provoc- 
ative of  the  attack,  and  other  and  more  important  agen- 
cies have  been  entirely  overlooked,  or  set  aside  as  the 
general  or  special  expressions  of  an  idiosyncrasy,  an  ex- 
planation which  is  practically  meaningless  and  conveys 
no  definite  or  intelligent  idea  concerning  the  essential 
nature  of  the  disease.  While  it  is  undoubtedly  true  that 
the  inhalation  of  certain  forms  of  matter,  and  pollen  is 
only  one  of  them,  exercises  an  unquestionable  irritative 
influence  in  the  production  of  the  paroxysm,  it  is,  at  the 
same  time,  equally  certain  that  in  a  large  proportion,  if 
not  all,  careful  inquiry  will  discover  this  influence  to  be 
purely  secondary  or  accidental — to  be  dependent  upon 
some  local  or  constitutional  condition.  Although  a 
number  of  investigators  had  previously  labored  with 
praisewortliy  zeal  to  establish  a  definite  pathology  of  the 
disease,  the  first  to  open  the  way  to  the  rational  solution 
of  the  problem  was  the  late  Dr.  George  M.  Beard,  of 
New  York,  who,  by  carefully  selected  statistics,  pointed 
out  the  importance  of  the  neurotic  element  as  a  factor  in 
its  production.*  According  to  Beard,  hay  fever  is  a 
neurosis,  a  functional  disease  of  the  nervous  system,  an 
affection  of  modern  life  and  of  the  nineteenth  centur3r. 
While  he  does  not  explain  exactly  in  what  such  a  neurosis 
consists,  while  his  researches  are  open  to  fair  criticism, 
and  while  his  conclusions  cannot  be  unreservedly  ac- 
cepted, they  served,  at  least,  the  important  purpose  of 
lifting  medical  thought  from  the  grooves  to  which  it  had 
been  confined  by  the  supporters  of  the  pollen  and  bacteria 
speculations,  and  diverting  it  into  newer  and  more  fruitful 
channels. 

Beard,  and  those  who  preceded  him,  not  only  depre- 
cated the  possible  etiological  importance  of  catarrhal 
affections  of  the  upper  air-passages,  but  went  so  far  as  to 
say  that  the  very  opposite  state  of  affairs  existed,  and 
that  the  subjects  of  "  hay  fever,"  so  called,  were  exempt 
from  nasal  and  other  forms  of  catarrh.  The  first,  perhaps, 
to  correct  this  erroneous  impression  and  to  point  out  the 
important  rdle  which  disease  of  the  naso-pharyngeal, 
cavities  plays  in  the  production  of  hay  fever  was  Dr.  Daley 
of  Pittsburg,  who,  in  1881,'  showed  that,  in  a  proportion  at 
least  of  cases,  there  is  local  disease  of  the  nose  or 
naso-pharynx,  without  which  the  exciting  cause  is  in- 
nocuous ;  and  futhermore  proved  by  clinical  evidence 
that  the  cure  of  the  affection  may  be  effected  through  the 
removal  of  the  local  intrinsic  condition. 

The  following  year.  Dr.  Roe,  of  Rochester,  published 
the  favorable  results  of  his  treatment  of  the  disease  by 
operative  procedures  directed  to  the  hypertrophied  mem- 
brane in  the  nasal  'chambers.'  According  to  Roe,  hay 
fever  is  caused  by  the  contact  of  the  pollen  of  grasses  or 
flowers  and  other  irritating  particles  in  the  atmosphere 
with  the  nasal  mucous  membrane,  which  in  certain  indi- 
viduals is  rendered  peculiarly  susceptible  by  virtue  of 
disease,  either  active  or  latent,  of  the  naso-pharynx, 
associated  with  hypertrophic  catarrh  of  the  nasal  passages. 

In  the  course  of  some  experiments  made  by  me  on 
the  healthy  and  diseased  mucous  membrane,  with  refer- 


»  Hay  Fever,  etc,  N.  V..  1876. 

*  Vide  Archives  of  Laryngology,  April  s,  1883.  Dr.  Edaon  had  previously 
(letter  to  New  York  Mboical  Record,  1878,  vol.  u.,  p.  3x7)  called  attention  to  the 
Uct  that  all  canes  of  the  disease  presented  one  or  more  of  certain  symptoms 
referable  to  the  nose,  as  great  sensitiveness  of  the  nasal  membrane,  coryxa,  per- 
sistent sternutation,  naso-pharyngeal  catarrh,  etc 

*  N.  V.  Medical  Journal,  May  13,  19,  1883. 


6o 


THE  MEDICAL  RECORD. 


[July  19,  1884. 


ence  to  nasal  cough  and  the  determination  of  an  area  in 
the  nostril  for  the  production  of  the  various  reflex  phe* 
nomena  associated  with  nasal  disease/  the  following 
facts  were  ascertained,  whose  application  to  the  disease 
in  question  will,  I  venture  to  think,  throw  some  addi- 
tional light  upon  its  pathology:  i.  That  in  the  nose 
there  exists  a  well-defined  sensitive  area,  whose  stimula- 
tion through  a  local  pathological  process,  or  through  ab 
extra  irritation,  is  capable  of  producing  an  excitation 
which  finds  its  expression  in  a  reflex  act  or  in  a  series  of 
reflected  phenomena.  2.  That  this  sensitive  area  corre- 
sponds, in  all  probability,  with  that  portion  of  the  nasal 
mucous  membrane  covering  the  turbinated  corpora 
cavernosa.  3.  That  nasal  cough  is  produced  only  by 
stimulation  of  this  area,  and  is  only  exceptionally  evoked 
upon  irritation  of  other  portions  of  the  mucous  mem- 
brane. 4.  That  all  parts  of  this  area  are  not  equally 
capable  of  generating  the  reflex,  the  most  sensitive  spots 
being  probably  represented  by  that  portion  of  the  mem- 
brane covering  the  posterior  end  of  the  inferior  turbi- 
nated body  and  the  septum  immediately  opposite.  5. 
That  the  tendency  to  evolution  of  reflex  phenomena 
varies  in  diflerent  individuals,  and  is  probably  dependent 
upon  the  varying  degree  of  excitability  of  the  erectile 
tissue.  In  some  the  slightest  touch  is  sufficient  to  excite 
the  reflex  act,  while  in  others  chronic  hyperemia  or  hy- 
pertrophy of  the  cavernous  bodies  seems  to  evoke  it  by 
constant  irritation  of  the  reflex  centres,  as  occurs  in 
similar  conditions  of  other  erectile  organs,  as,  for  exam- 
ple, the  clitoris. 

Apart  from  experimental  proof  of  such  localization — 
viz.,  to  the  posterior  and  inferior  portion  of  the  nostril — " 
I  showed,  from  my  clinical  observation,  (i)  that  in  oases 
where  reflex  cough  is  present,  these  are  the  portions 
chiefly,  if  not  solely,  involved ;  (2)  that  the  act  may  be 
produced  here  at  will  by  artificial  stimulation  of  the  dis- 
eased area,  and  (3)  dissipated  by  local ,  applications  to, 
or  removal  of  the  same ;  (4)  that  foreign  bodies  only 
excite  cough  when  they  are  imparted  in  the  sensitive 
area ;  and  (5)  that  polypi  give  rise  to  reflex  phenomena  only 
when  they  arise  from  or  impinge  upon  the  sensitive  por- 
tions of  the  area ;  and  lastly,  a  point  of  importance 
as  bearing  on  the  treatment,  (6)  that  where  complete 
atrophy  of  the  turbinated  structures  exists,  as,  for  exam- 
ple, in  certain  cases  of  ozoena,  reflex  cough  is  not  pres- 
ent, nor  can  it  be  induced  by  artificial  stimulation. 

These  facts  are  not  alone  true  of  cough  and  asthma ; 
my  experience  furnishes  me  with  a  series  of  cases  where 
they  could  be  demonstrated  as  true  of  various  other 
reflex  phenomena  originating  in  diseased  conditions  of 
this  area,  and  I  have  already  called  attention  to  the 
reflexes  ■  which  I  have  met  with  (cough,  pain  in  the  ear 
and  larynx,  redness  of  drum  membrane,  etc.)  in  the 
course  of  operative  procedures  in  this  region.* 

Since  I  first  directed  attention  to  the  posterior  end  of 
the  inferior  turbinated  body  and  septum  as  the  most  sen- 
sitive spots  to  reflex-producing  impressions,  I  have  re- 
ceived several  communications  confirmatory  of  the  views 
expressed  in  my  paper,  which  have  also  derived  support 
from  the  publications  of  other  writers.  Thus,  the  obser- 
vation that  reflex  asthma  arises  from  nasal  disease  only 
when  the  posterior  portions  of  the  sensitive  area  are  in 
some  way  involved,  either  directly  from  a  pathological 
condition  of  the  parts  or  from  the  irritation  of  a  poly- 
pus,* has  been  confirmed  by  Dr.  Roe,*  who  explains  the 

>  On  Nasal  Cough,  and  the  Extatence  of  a  Sensitive  Reflex  Area  in  the  Nose, 
American  Journal  of  Medical  Sciences,  July,  1883.  The  results  of  these  experi- 
ments were  first  brought  before  the  Baltimore  Medical  Association  in  the  early 
Kt  of  .S883,  and  subsequently  before  the  Medico-Chirurgical  Faculty  of  Mary 
,  d  (April,  X883,  viiU  Iransacttons),  and  the  American  Laryngological  Assoda- 
tiOQ  (May,  1883,  vide  Transactions). 

»  Trans.  Med.  Chir.  Fac  of  Maryland,  1884.  American  J.  Med.  Sc,  loc.  cit.. 
Trans.  Vurgmia  State  Society,  1883. 

*  There  is  one  point  pertinent  to  the  subject  of  this  paper  which  should  not  be 
lost  sight  of,  and  that  is  that  certain  reflex  phenomena  may  be  awakened  by  stim- 
ulation of  the  apparently  normal  membrane. 

«  Vidt  a  paper  by  the  author  on  Reflex  Cough  due  to  Nasal  Polypi,  etc.  (read 
April  as,  1884).  Trans.  Med.  Chir.  Fac  of  Maryland,  and  N.  V.  Medical  Rbc- 
ORD,  May  4,  1884. 

*  Journal  of  the  American  Medical  Association,  September  15, 1883. 


more  frequent  occurrence  of  the  paroxysms ;  at  night 
by  the  gravitation  of  blood  to  the  sensitive  area.  The 
same  author,  moreover,  in  his  recent  paper  on  '*hay 
fever/'  *  points  out  the  fact  that,  in  the  majority  of  cases, 
the  seat  of  irritation  during  the  attack  is  the  inferior  tur- 
binated bone  and  posterior  portion  of  the  septum,  thus 
furnishing  additional  confirmatory  clinical  evidence  in 
favor  of  localization  of  the  reflex  area  in  the  lower  and 
posterior  portions  of  the  nostril.*  While  these  observa- 
tions go  to  show  that  the  most  sensitive  spots  are  repre- 
sented by  the  area  indicated  above,  it  is  but  fair  to  state 
that  a  different  opinion  is  entertained  by  a  German  con- 
frere, well  known  from  his  labors  in  this  special  field. 
In  August,  1883,  ^^^1*^  appeared  in  Germany  an  inter- 
esting brochure  from  the  pen  of  Dr.  Haek,  of  Freiburg,* 
in  which  this  writer  maintains,  as  the  result  of  indepen. 
dent  experiment,  that  the  anterior  extremity  of  the  inferior 
turbinated  bone  is  the  point  from  which  all  reflexes  take 
their  origin,  and  that  those  arising  from  stimulation  of 
other  portions  of  the  nostril  only  occur,  secondarily, 
through  congestion  of  the  cavernous  tissue  of  this  cir- 
cumscribed locality. 

Like  Daly  and  Roe,  Haek  holds  that  morbid  con- 
ditions of  the  nasal  membrane  play  the  most  important 
part  in  the  etiology  of  the  disease.  He  also  believes 
that  there  are  two  factors  in  the  production  of  the  par- 
oxysm, viz.,  a  hyperaesthetic  condition  of  the  terminal 
filaments  of  the  fifth  and  olfactory  nerves,  and  an  in- 
creased irritability  of  the  cavernous  tissue,  caused,  as  a 
rule,  by  local  nasal  disease,  and  inclines  to  the  belief 
(also  held  by  Roe)  that  the  neurasthenic  symptoms  are 
secondary  to  the  nasal  affection,  calling  attention,  at  the 
same  time,  to  the  fact  that  the  latter  may  coexist  with  a 
general  neurosis  without  having  any  connection  with  it* 

Finally,  Dr.  Harrison  Allen  advances  the  view*  that 
"hay  fever"  depends  solely  upon  obstruction  of  the 
nostrils  (from  deflection  of  the  septum,  hypertrophy  of  soft 
parts  and  bone,  turgescence  of  nasal  mucous  membrane), 
and  that  the  cure  consists  simply  in  removing  the  ob- 
struction (or  tendency  thereto)  in  the  nasal  chambers. 
According  to  his  experience,  sufferers  from  hay  fever  and 
allied  disorders  have  one  feature  in  common — the  in- 
ferior turbinated  bones  lie  well  above  the  floor  of  the 
nostril,  an  anatomical  peculiarity  which  subjects  their 
bulging  mucous  membrane  to  additional  irritation  from 
extraneous  substances.* 

It  would  appear,  then,  that  the  truth  is  irresistibly 
emerging  into  recognition  that  certain  abnormal  con- 
ditions of  the  nasal  passages  are  necessary  to  the  pro- 
duction of  the  ensemble  of  phenomena  which  form  the 
classical  picture  of  so-called  hay  asthma.  Although  the 
results  arrived  at  by  different  observers,  working  inde- 
pendently of  each  other,  and  starting  out  in  some  in- 
stances from  different  standpoints,  are  not  altogether 
harmonious,  they  present  nevertheless  a  singular  unanimity 
in  their  convergence  to  a  common  point — in  thieir  recog- 
nition of  the  importance  of  remedial  measures  addressed 
to  the  nasal  chambers  as  a  prime  factor  in  the  therapeutic 
management  of  the  disease.  While,  then,  it  is  probably 
true  that  certain  states  of  the  nasal  passages  are  neces- 
sary to  the  production  of  a  paroxysm,  it  is,  at  the  same 
time,  equally  demonstrable  that  these  are  not  always  de- 
pendent upon  well-defined  local  nasal  disease,  but  that, 
in  a  number  of  cases,  such  conditions  are  originally 
brought  about  by  abnormal  excitability  of  the  vasomotor 
centres  from  inherited  or  acquired  disease.  The  prob- 
lem, then,  presents  for  consideration  two  important  con- 

^  N.  V.  Medical  Journal,  May  3  and  10^  1884. 

*  In  a  recent  number  of  L* Union  M^dicale  (January  aa,  1884,  La  toux  nasale) 
M.  Longuet  believes,  with  me,  in  the  existence  of  a  tussigenicarea  {aone  tustighu\ 
in  the  posterior  end  of  the  inferior  turbinated  bone  and  septum,  whidi  he  com- 
pares \o  the  hystero  and  epileptogenic  zones  of  Krown-S^uard. 

*  Ueber  eine  operative  Radicalbehandlung  bestimmter  Formen  von  MigrXne, 
Asthma,  Heufieber,  etc    Wiesbaden,  1884. 

*  Sec  also,  Wiener  Med.  Wochenschrift,  No.  14,  1883. 

*  American  Journal  Med.  Sctenoes,  January,  1884. 

*  Allen  reports  several  cases  successfully  treated  by  lemoving  the  obstruction  to 
respiration.  Cases  have  also  been  treated  with  the  cautery  by  Dr.  Sajousot 
Philadelphia  (reported  at  last  meeting  of  the  American  Laryngological  Associa- 
tion}, whose  conclusions  on  the  subject  do  not  differ  from  those  of  Dr.  Roe. 


July  19,  1884.] 


THE  MEDICAL  RECORD. 


6i 


ditioos;  on  the  one  hand  the  local  nasal  phenomena, 
and  on  the  other  the  etiological  relations  of  the  central 
nervous  system.  In  allotting  to  each  its  respective 
aasative  significance,  care  should  be  taken,  in  avoiding 
theScyliaof  the  neurologist,  not  to  be  too  closely  attracted 
to  the  Charybdis  of  another  form  of  specialism. 

Approaching  the  question  from  this  standpoint,  and 
guided  by  my  personal  experience,  I  believe  that  our 
definite  knowledge  of  the  etiology  of  the  disease  may  be 
briefly  expressed  as  follows  : 

I.  The  essential,  distinguishing  feature  of  the  paroxysm 
of  so-called  "  hay  asthma "  resides  in  an  exalted  con- 
dition (erethism)  of  the  nasal  erectile  tissue,  and  especi- 
ally that  portion  occupying  the  posterior  end  of  the 
inferior  turbinated  bone  and  the  septum  immediately 
opposite.  This  latter  area  corresponds  to  the  distribu- 
tion of  the  spheno-palatine  branches  of  the  superior 
maxillary  nerve,  as  distinguished  from  the  nasal  branch 
of  the  ophthalmic,  which  latter  supplies  the  more  anterior 
portions  of  the  nasal  fossas.  The  former  nerves,  derived 
through  the  ganglion  of  Meckel,  probably  therefore  con- 
tain the  vaso-motor  nerves  which  govern  the  erection  of 
the  turbinated  tissue,  and  hence  the  localization  of  the 
sensitive  area  becomes  the  key  to  the  mechanism  of  the 
paroxysm  and  brings  us  nearer  the  solution  of  the  path- 
ological process  that  sets  it  id  motion. 

So  far  as  my  observation  goes,  every  attack  is  attended 
with  more  or  less  swelling  of  the  erectile  tissue,  which  is 
more  pronounced  in  the  lower  and  posterior  parts  of  the 
nostril.  This  swelling,  occasionally  inconsiderable,  is 
often  sufficient  to  produce  absolute  and  complete  closure 
of  the  nasal  fossae.  I  have  moreover,  so  far,  never  seen, 
nor  have  I  been  able  to  find  the  record  of  a  single  case 
where  paroxysms  of  hay  fever  occurred  where  the  tissue 
was  completely  atrophied  or  destroyed  by  disease.  In 
two  cases  under  my  observation,  the  nasal  chambers  were 
markedly  capacious,  but,  at  the  same  time,  the  erectile 
tissue  was  well  developed.  Finally,  the  cure  of  the 
affection  by  the  artificial  destruction  of  the  erectile  bodies 
amounts  to  a  demonstration. 

2,  This  exaggerated  iiritability  of  the  cavernous  tissue 
may  be  directly  due  to  the  constant  presence  of  con- 
gestk)n  or  other  pathological  conditions  of  that  structure, 
the  result  of  direct  or  indirect  (reflex)  irritation  from 
ci  extra  influences,  plus  a  hypersensitive  condition  of 
the  vasomotor  centres  begotten  of  their  prolonged  ex- 
diation  by  the  irritating  influence  in  the  nostril ;  or  it 
nay  be  brought  about,  in  the  first  instance,  by  an  exalted 
state  of  the  central  nervous  system,  leading  eventually 
CD  disordered  functional  activity  of  the  vasomotor  nerve- 
centres;  or,  finally,  a  hypersensitive  condition  of  the 
latter  may  be  conditioned  by  other  pathological  states 
of  the  system  as  a  whole,  or  as  the  result  of  reflected 
initation  frona  its  individual  parts. 
I  am  inclined,    therefore,   to   transfer  the   point  of 
potest  excitability  from  the  peripheral  ends  of  the 
aw  filaments  to  the  nerve-centres  themselves.     While 
1  do  not  deny  the  possibility  of  a  hyperaesthetic  condi- 
^  or  even  organic  changes  in  the  terminal  filaments 
of  the  sensitive  nerves,  as  an   occasional  factor,  and 
•tnlc  fully  aware  of  the  want  of  experimental  proof  in 
^  of  the  view  advanced,  still  it  seems  to  me  a  more 
*^uate,  a    more   comprehensive  explanation   of  the 
'sicd  phases  of  the  disease.     Upon  this  theory  can  be 
**«t  explained,  moreover,  the  occurrence  of  paroxysms 
b*J  irritation  reflected  from  various  parts  of  the  "body 
*ttaotc  from  the  nasal  passages.     The  weight  of  clinical 
•"ycnce,  too,  is  in  favor  of  disordered  functional  activity 
of  the  nerve-centres,  as  against  organic  alteration  of  the 
peripheral  sensitive  nerves.     Finally,  it  is  probably  not 
tf  dK  terminal  ends  of  these  filaments,  but  in  the  centres 
themselves,  that  the  perception  is  awakened  which  dif- 
fcrentiatcs  one  form  of  irritant  from  another ;  that  the 
iKnres  themselves  are  but  the  passive  channels  through 
^htt  the  impression  is  transmitted,  and  that  the  pro- 
^Ktion  of  a  paroxysm  by  a  given  irritant  will  depend, 


other  things  being  equal,  upon  the,  so  to  speak,  dis- 
criminating power  or  peculiar  susceptibility  of  the  centres 
themselves. 

3.  There  is  practically  an  infinitude  of  causes,  ex- 
ternal and  internal,  which  may  precipitate  the  nasal 
orgasm,  such  as  various  forms  of  matter  suspended  in 
the  atmosphere  (pollen,  different  forms  of  animal  life, 
etc.),  or  the  erection  of  the  tissue  may  be  conditioned 
by  those  influences  that  are  commonly  productive  of 
erection  of  the  nasal  corpora  cavernosa,  such  as  varying 
meteorological  relations,  various  forms  of  reflected  irrita- 
tion, or,  finally,  it  may  be  occasioned  through  psychical 
causes.  It  follows,  therefore,  as  a  corollary  to  the  above, 
that  any  one  irritant  is  insufficient  of  itself  to  provoke 
the  attack,  the  latter  being  only  possible  either  from 
disordered  functional  activity  of  the  nerve-centres,  ^or 
local  structural  disease. 

4.  The  power  of  a  given  local  irritant  to  produce 
such  impression,  and  the  violence  of  the  resulting  attack, 
in  all  probability  depends  upon  its  physical  properties 
and  the  length  of  its  sojourn  in  the  nasal  cavities.  Thus, 
the  peculiar  glutinous  nature  of  some  substances,  as  for 
example  pollen,  the  irregular  surfaces  of  others,  as  the 
golden-rod  *  and  similar  substances,  will  give  rise  to  more 
prolonged  irritation  than  substances  of  smooth  contour, 
which  are  readily  swept  out  of  the  nostrils. 

5.  Apart  from  its  accidental  occurrence  with  the  flow- 
ering of  certain  plants,  etc.,  the  marked  periodicity  of 
the  paroxysm  in  some  cases,  its  regular  appearance  at 
a  certain  hour  and  on  a  certain  day,  so  far  from  over- 
throwing its  neurotic  nature,  points  to  some  functional 
derangement  as  its  possible  cause.  This  tendency  to 
periodical  return  of  a  given  state  is  characteristic  of  cer- 
tain morbid  states  of  the  nervous  system,  of  which  the 
so-called  functional  aphonia  is  a  prominent  example. 
It  is  not,  therefore,  stepping  beyond  the  bounds  of  legiti- 
mate speculation  to  suggest  this  as  the  explanation  of  a 
certain  number  of  cases. 

6.  Whatever  be  the  original  cause  of  such  special 
tendency  to  erection  and  consequent  evolution  of  reflex 
phenomena,  the  essential  part  of  the  mechanism  of  the 
paroxysm  is  the  orgasm  of  the  erectile  area.  This  is  the 
main-spring  of  the  machinery  by  which  it  is  set  in  mo- 
tion, and  without  which  the  onset  of  the  attack  is  im- 
possible. 

From  what  has  been  said  above,  it  naturally  follows 
that  the  rational  treatment  will  consist  (i)  in  diminishing 
the  reflex  excitability  of  the  turbinated  tissue  ;  or,  fail- 
ing in  that,  (2)  the  partial,  or,  if  necessary,  complete 
destruction  of  the  tissue  itself. 

The  first  indication  must  be  met  (r)  by  tonic  renjedies 
addressed  to  the  nervous  system,  and  by  the  exhibition 
of  such  drugs  and  methods  as  experience  has  shown 
control  reflex  excitability  (the  bromides,  belladonna, 
chloral,  counter- irritation  to  nape  of  the  neck,  etc.)  ;  (2) 
by  the  careful  search  for,  and  intelligent  treatment  of 
any  pathological  condition  which  may  be  regarded  as  a 
source  of  reflected  irritation  ;  and  (3)  by  simple  topical 
treatment  of  any  existing  nasal  disease  or  irritation.  In 
carrying  out  the  second  indication  care  should  be  taken 
to  sacrifice  as  little  of  the  erectile  tissue  as  possible.  It 
would  accordingly  be  better  to  commence  by  removing 
or  destroying  that  portion  which  covers  the  posterior 
end  of  the  inferior  turbinated  bone,  and,  if  necessary, 
that  covering  the  septum  immediately  opposite ;  or,  in 
other  words,  that  area  which  contains  the  greatest 
number  of  filaments  of  the  sphenopalatine  nerve.  Should 
this  not  accomplish  the  desired  result,  any  additional 
sensitive  spots  should  be  located  by  means  of  the  probe, 
as  has  been  done  by  Roe,  and  appropriate  treatment 
adopted. 

The  destructive  agent  used  in  any  given  case  will  vary 
according  to  circumstances.     It  may  be  said,  in  general, 

1  The  golden-rod  has  also  been  regarded  as  the  cause  of  hay  iever.  See  editorial 
article  on  the  Pathology  of  Hay  Fever,  by  Dr.  .Frank  Woodbury,  in  the  Phila. 
Med.  Times,  December  x,  1883.  p.  175. 


62 


THE  MEDICAL  RECORD. 


[July  19,  1884. 


that  hypertrophic  enlargements  of  the  turbinated  bodies 
are  best  removed,  if  practicable,  with  the  cold  wire 
snare  ;  swelling  of  the  cavernous  tissue  over  the  septum 
is  best  treated  with  the  galvano-cautery,  while  for  com- 
plete destruction  of  erectile  tissue,  the  latter  agent  or 
electrolysis  is  the  best  agent  we  possess. 

Reference  has  been  made  several  times  above  to  re- 
flected irritation  of  a  distant  organ  as  a  factor  in  the 
production  of  the  paroxysm.  In  order  to  illustrate  this 
point,  and  at  the  same  time  make  good  the  assertion  of 
the  fact,  I  will  insert  the  following  case  : 

Mrs.  ,  aged  thirty-seven  years,  married  twenty 

years,  the  mother  of  one  child,  now  eighteen  years  of 
age,  came  in  the  early  part  of  April  of  this  year  to  con- 
sult me  on  account  of  severe  "  hay  fever."  She  has  re- 
sided all  her  lifetime  in  a  small  manufacturing  town  on 
the  banks  of  one  of  our  Maryland  rivers,  and  in  proximity 
to  a  malarial  district.  Family  history  unimportant.  Sev- 
eral of  the  neighbors  suffer  from  paroxysms  similar  to  her 
own.  She  is  herself  a  woman  of  average  intelligence,  of 
spare  habit,  dark  hair  and  eyes,  good  disposition,  not  in- 
clined to  be  hysterical,  nor  easily  frightened ;  is  "  dys- 
peptic," and  siiffers  greatly  from  inability  to  digest  her 
food.  Without  possessing  a  decidedly  nervous  tempera- 
ment, in  the  common  acceptation  of  the  term,  a  more 
or  less  pronounced  neurotic  tendency  expresses  itself  in 
a  certain  unnatural  acuteness  of  the  senses,  and  suscepti- 
bility to  psychical  impressions.  Has  never  suffered  from 
any  nervous  disease,  with  the  exception  of  occasional 
neuralgic  pains  in  the  course  of  the  fifth  nerve,  which 
have,  however,  of  late,  ceased  to  give  her  much  trouble 
or  concern.  Has  had  malarial  fever,  and  for  the  past 
four  years  has  suffered  from  constant  ovarian  trouble. 
The  left  ovary  is  probably  the  only  one  involved,  the 
condition  being  some  chronic  inflammatory  disease. 
Has  suffered  for  two  years  from  "hay  fever."  Prior 
to  her  ovarian  trouble,  enjoyed  excellent  health  and 
exhibited  no  tendency  to  catarrhal  disease  of  the  nose 
or  throat. 

The  paroxysms  are  ushered  in,  as  a  rule,  by  chilly 
sensations,  followed  by  violent  and  uncontrollable  sneez- 
ing, intense  redness  of  the  conjunctivae,  increased  lachry- 
mation  and  spasm  of  the  lids.  During  the  attack  she 
cannot  see  to  read  or  write,  any  attempt  to  use  the  eyes 
being  accompanied  by  great  pain,  photophobia,  etc. 
The  voice  soon  becomes  husky  and  nasal,  considerable 
mucus  b  expectorated  from  the  throat,  and  a  profuse 
watery  and  slightly  mucous  secretion  is  discharged  in 
abundance  from  the  nostrils.  There  is  generally  super- 
added to  these  symptoms  a  short  barking  cough,  which 
often  continues  for  several  days  after  the  subsidence  of 
the  attack.  During  the  latter,  the  nostrils  are  always 
completely  closed,  so  that  nasal  respiration  is  impos- 
sible. Pain  is  felt  across  the  bridge  of  the  nose  and  in 
the  frontal  and  occipital  regions,  pain  in  the  ears  and 
tinnitus  are  nearly  always  experienced,  and  the  meatuses 
feel  as  if  stopped  up  by  a  foreign  body.  The  amount  of 
asthma  accompanying  the  attack  varies  greatly,  being  at 
times  more  pronounced  than  at  others.  During  the 
paroxysm  pain  is  always  felt  in  the  left  ovary,  and  any 
existing  pain  of  that  organ  aggravated.  The  ovarian  pain 
comes  on  after  sneezing,  and  occasionally  continues  after 
the  paroxysm  has  subsided.  The  attacks  come  on  at  all 
seasons  of  the  year,  and  bear  no  definite  relation  to  the 
conditon  of  the  atmosphere  as  regards  moisture  or  dry- 
ness ;  but  are  worse  in  spring  and  fall,  i>.,  in  the 
seasons  of  greatest  temperature  changes.  They  come 
on  at  all  hours  of  the  day,  and  she  is  often  awakened 
from  her  sleep  by  the  sudden  accession  of  a  paroxysm. 
The  sh'ghtest  exposure  to  draughts  of  any  kind  suffice  to 
bring  on  the  attack  ;  the  accidental  unfastening  of  her 
night-dress  at  the  neck  during  sleep,  stepping  from  the 
bed  to  the  floor,  going  about  in  her  stocking  feet,  or 
changing  her  shoes  for  her  slippers,  and  other  equally 
trivial  causes  have  frequently  precipitated  it.  It  is  also 
brought  on  by  physical  or  mental  over-exertion,  or  by 


emotional  excitement.*  The  attacks  are  not  modified  by 
diet,  dust  has  little  or  no  effect,  while  gas  and  smoke  of 
various  kinds  produce  a  disagreeable,  smothering  sensa- 
tion with  some  dyspnoea,  but  are  insufficient  to  provoke 
the  characteristic  phenomena  of  the  paroxysm.  There 
are  some  plants  that  cause  slight  sneezing ;  but  although 
frequently  exposed  to  a  pollen-laden  atmosphere,  ex- 
posure has  .never  produced  a  paroxysm.  The  attacks 
invariably  appear  and  are  moire  severe  at  the  menstrual 
period,  appearing  sometimes  at  its  commencement, 
sometimes  at  its  close.  This  latter  condition  of  affairs 
has  lasted  for  one  year.  They  last  generally  for  two  days 
and  one  night,  after  which  all  the  discomfort  she  suffers 
from  them  passes  gradually  away.  She  averages  about 
two  attacks  a  week,  during  which  she  is  confined  to  her 
room,  and  often  to  bed.  They  sometimes  leave  her  in 
a  state  of  nervous  prostration,  from  which  she  slowly 
recovers. 

By  the  protection  of  the  nasal  passages  from  the  con- 
tact of  air  during  the  attack,  the  paroxysms  are  somewhat 
mitigated  in  severity,  except  at  the  monthly  period, 
when  this  has  no  effect.  Residence  at  the  sea-shore  in- 
variably gives  relief ;  except  during  menstruation,  when 
the  attack  is  as  severe  as  when  at  home. 

During  the  intervals  between  the  attacks,  she  does 
not  suffer  from  nasal  or  throat  trouble,  beyond  the  ac- 
cumulation of  a  slight  amount  of  mucus  in  the  nasal 
passages  upon  arising  in  the  morning,  with  occasional 
dryness  of  the  throat  and  huskiness  of  the  voice.  These 
phenomena  are,  moreover,  of  quite  recent  development. 

Physical  examination, — Nothing  to  indicate  visceral 
disease,  apart  from  the  morbid  condition  of  the  ovary. 
No  disease  of  auditory  apparatus,  larynx,  trachea,  or 
lungs.  Anterior  nasal  passages  apparently  perfectly 
healthy.  The  posterior  extremities  of  the  inferior  turbi- 
nated bodies,  as  seen  in  the  rhinoscopic  mirror,  without 
being  notably  enlarged,  present  an  ashy  gray  color  often 
seen  in  hypertrophy  of  these  bodies.  The  nasal  fossae 
are  perfectly  free  and  symmetrical  The  lower  border  of 
the  inferior  turbinated  bones  cannot  be  seen  in  the  mir- 
ror, and  are  not  elevated  above  the  nasal  floor  in  front. 
There  is  no  malformation  or  irregularity  in  the  skeleton 
of  the  nose  or  other  part  of  the  face.  The  mucous  mem- 
brane of  the  nasal  pharynx  is  congested,  and  covered 
here  and  there  with  a  faint  film  of  transparent  secretion. 
The  mouths  of  the  Eustachian  tubes  are  normal,  in  ap- 
pearance. The  lower  pharynx  is  congested  and  studded 
here  and  there  with  small  granules  (commencing  granu- 
lar pharyngitis).  No  irregularity  in  the  conformation  of 
the  pharyngeal  cavities. 

The  treatment  adopted  in  this  case  was  in  accordance 
with  the  indications  laid  down  above,  with  special  at- 
tention to  the  diminution  of  excitability  of  the  erectile 
area.  The  nasal  passages  were  kept  thoroughly  cleansed 
and  protected  against  local  irritation.  Anodyne  and  al- 
terative applications  and  acetic  acid  were  made  to  the 
congested  surfaces  with  the  understanding  that,  should 
they  fail  to  relieve,  the  galvano-cautery  was  to  be  re- 
sorted to. 

At  the  end  of  one  week  little  improvement  was  no* 
ticed  ;  but  at  the  close  of  the  second  marked  change  for 
the  better  had  occurred,  both  as  regards  the  number  and 
severity  of  the  paroxysms.  At  the  expiration  of  six 
weeks  the  attacks  had  lost  their  distinguishing  characters, 
the  only  annoyance  from  which  the  patient  suffered  bein^ 
an  occasional  brief  access  of  sneezing.  At  the  two  men- 
strual periods  which  intervened  during  this  time,  how- 
ever, she  had  attacks  resembling  the  original  paroxysna, 
but  greatly  modified  in  severity.  At  the  present  writing, 
the  sneezing  has  so  markedly  diminished,  that  it  no  long— 
er  gives  her  much  concern,  and  her  last  monthly  period 
was  passed  without  the  slightest  nasal  discomfort,  although, 
she  was  convinced  that  it  was  inevitable,  and  had  pre— 

>  The  patient  attributes  a  great  deal  of  her  trouble  to  the  excitement  and  aiental. 
anxiety  which  she  underwent  while  in  constant  care  of  the  wounded  in  her  hua — 
band's  factory,  where  accidents  to  the  hauids  were  constantly  occurring. 


July  19. 1884.] 


THE  MEDICAL  RECORD. 


63 


pared  herself  for  the  attack.  What  the  final  result  of  this 
case  will  be  I  am,  of  course,  unable  to  say,  but  from  the 
present  outlook,  operative  procedures  will  doubtless  be 
unnecessary. 

Remarks. — ^The  above  case  shows,  among  other  things, 
that  the  paroxysms  of  the  disease  commonly  called  '^  hay 
fever,"  may  be  brought  on  in  the  same  individual  by  a  va- 
riety of  agencies  differing  entirely  in  origin,  character, 
and  mode  of  operation.  At  times  they  are  produced  by 
causes  which  are  ordinarily  provocative  of  common  coryza, 
at  others  from  the  increased  irritative  stimulus  given  to  a 
morbid  process  in  a  distant  organ,  or  finally,  they  are 
occasioned  by  impressions  of  a  purely  psychical  nature. 

The  attacks  at  the  menstrual  epoch  are  readily  explicable 
bythe  physiological  erection  of  the  nasal  corpora  cavernosa 
iriuch  occurs  at  that  period ;  for,  as  I  have  pointed  out 
elsewhere,'  in  a  certain  proportion  of  women  these  bod- 
ies become  enlarged  and  engorged  during  menstruation, 
the  swelling  of  the  membrane  subsiding  with  the  cessa- 
doa  of  the  catamenial  flow.  This  turgescence  may  be  bi- 
lateral, or  confined  to  one  side»  may  be  inconsiderable  and 
give  rise  to  no  inconvenience,  or,  on  the  other  hand,  the 
svollen  bodies  may  include  the  nostrils  and  give  rise  to 
various  reflex  phenomena.  In  the  ''  hay  fever  "  sufferer, 
anything  that  tends  to  produce  swelling  of  this  tissue 
excites  at  the  same  time  the  tendency  to  the  production 
of  the  reflex  phenomena  characteristic  of  the  disease. 
In  thb  particular  case  the  chief,  and,  under  certain  cir- 
cumstances, the  sole  excitant  of  the  paroxysm  was^the 
utero-ovarian  excitant  of  the  menstrual  epoch. 

The  history  would  point  to  a  hypersensitive  condition 
of  the  vasomotor  nerve-centres,  the  result,  perhaps,  of  con- 
stant irritation  reflected  from  the  diseased  ovary,  as  the 
chief  predisposing  cause,  or  so-called  ^^idiosyncradc"  influ- 
ence in  this  particular  case.  It  is  fair,  too,  to  look  upon 
the  increased  excitability  of  the  erectile  bodies,  and  the 
consequent  repeated  attacks  of  cough,  as  responsible  for 
the  amount  of  existing  nasal  disease. 

The  practical  outcome  of  the  above  conception  of  the 
disease  is  simply  this :  Those  who  recognize  in  it  the 
imndation  of  a  rational  therapeutic,  and  direct  their  treat- 
ment accordingly,  will  relieve  all,  and  cure  a  large  pro« 
portion  c^  their  patients ;  while  those  who  blindly  ac- 
cept the  traditional  fallacies  of  the  theory  of  external 
canses  must  continue  to  divert  themselves  with  perpet- 
ual palliative  experiment,  and  cling  to  the  gloomy  belief 
of  die  Englishman,  that  the  only  cure  for  the  disease  is 
patience,  if  removal  from  the  British  Isles  is  impossible, 
tfaanking  God,  at  the  same  time,  that  there  are  only  thirty 
days  in  June !  *  

Apocymum  Cannabinum. — Canada  or  American  Indian 
hemp  bark  has  a  very  persistent  bitter  taste,  contains 
taanin  and  gallic  acid.  Is  sometimes  emetic,  and  causes 
diaphoresis ;  also  cathartic,  like  jalap.  It  promotes  ex* 
peroration,  also  drowsiness,  increases  the  urinary  secre* 
tioQ  and  diminishes  the  force  and  fervency  of  the  pulse, 
like  aconite  or  digitalis.  It  is  most  used  in  dropsy,  and 
IS  a  tonic  and  alterative  in  dyspepsia.  Dose  of  pow- 
dered root,  five  grains,  as  an  anti-periodic,  twenty  grains 
as  an  emetic.  Decoction  of  |  j.  to  Ojss.  of  water,  and 
boiled  down  to  a  pint ;  a  wineglassful  three  times  a  day, 
as  a  diuretic,  or  3  j.  of  the  bark  of  the  root  in  |  viij. 
of  water,  %  ss.  every  six  or  eight  hours.  This  is  one  of 
those  remedies  which  should  always  be  thought  of  in  ob- 
i&Date  cases  of  cardiac  or  hepatic  dropsy.  Its  diuretic 
actioD  is  frequently  prompt  and  even  extraordinary.  It 
isthe  basis  of  Hunt's  remedy  for  renal  diseases.  Although 
apocynom  is  us^  by  some  as  gin  and  bitters,  yet  it  is  very 
<isa^able  to  others,  and  some  persons  far  advanced  in 
dropsjr  will  almost  rather  die  than  swallow  the  simple  in- 
^m.  A  large  addition  of  chimaphila  or  wintergreen 
vill  aid  its  diuretic  powers  and  improve  its  taste. 

^\auam  of  the  Scmal  Appaiatus  as  an  Etiological  Factor  in  the  Production 
"  Xml  Disease.    American  Journal  Med.  Sciences,  April,  1884. 
1  Yi4g\etia  to  British  Med.  Journal,  1883,  p.  1315. 


WARBURG'S  TINCTURE. 

Hints  for  Simplifying  and  Cheapening  It. 

By  JOHN  C  PETERS,  M.D., 

NEW  Yont ' 

Some  time  ago  I  was  so  impressed  with  tbe  shrewd  hints 
of  The  Record  about  Warburg's  tincture  that  I  have 
made  a  careful  study  of  that  complex  preparation/ which 

1  hope  will  be  instructive  to  its  readers. 

In  the  tincture  42  ounces  of  various  ingredients  are  to  be 
dissolved  in  500  parts  of  proof  spirit,  which  is  about  half 
alcohol  and  half  water,  by  placing  them  in  a  water-bath 
for  twelve  hours,  then  expressing  them  and  adding  10 
ounces  of  disulphate  of  quinine,  the  whole  mixture  being 
replaced  in  the  water-bath  until  all  the  quinine  is  dis- 
solved. 

The  process  seems  simple,  but  it  may  safely  be  assumed 
that  a  great  residuum  of  resinous,  bitter,  and  aromatic 
substances  will  be  left  behind. 

Next  to  quinine  the  most  important  ingredient  is  aloes, 
of  which  I  lb.  British,  or  16  ounces  avordupois,  or  7,000 
grains  are  to  be  dissolved  in  the  500  ounces  of  proof 
spirit.  There  arc  next  4  ounces,  or  1,750  grains  of 
rhubarb.  Third,  4  ounces,  or  1,750  grains  of  angelica 
seeds,  which  is  a  simple  aromatic  tonic,  spice,  or  stim- 
ulant, like  aniseed,  calamus,  and  the  like.  Fourth,  4 
ounces,  or  1,750  grains  of  the  so-called  confectio  datno- 
craiis,  which  is  a  mild  confection  of  opium,  which  once 
contained  sixty-two  ingredients,  with  about  5  grains  to 
the  ounce  of  opium.  Nearly  a  century  ago  the  London 
physicians  substituted  the  confectio  Londonense^  made 
of  opium,  6  drachms;  long  pepper,  i  ounce;  ginger, 

2  ounces;  caraway  seeds,  3  ounces;  syrup,  i  pmt. 
There  is  i  grain  of  opium  in  every  36  grains,  and  the 
dose  is  10  to  30  grains.  Hooper  says :  '*  To  the  credit 
of  modern  pharmacy  this  is  almost  the  only  confection  of 
opium  that  now  remains  of  all  those  complicated  and 
confused  preparations  called  Damocratis»  Mithridate, 
Theraic,  etc.  It  more  nearly  approximates  the  virtues 
of  all  of  them  than  any  other,  and  may  be  considered  an 
effectual  substitute  for  them  in  practice.  It  is  a  very 
warm  and  stimulating  confection  and  admirably  calcu- 
lated to  soothe  pain  and  restlessness,  and  sustain  strength 
in  low  fevers."  Fifth,  2  ounces,  or  875  grains  of  elecam- 
pane^ or  less  than  2  grains  to  the  ounce :  all  its  virtue 
a  redue  to  a  slightly  peculiar  camphor,  which  giyes  it  its 
odor.  Sixth,  2  ounces  of  saflfron.  Seventh,  2  ounces  oL 
fennel  seeds.  Eighth,  i  ounce,  or  less  than  i  grain  to  the 
ounce,  of  gentian.  Ninth,  i  ounce  of  zedoary,  which  is 
almost  identical  with  ginger.  Tenth,  i  ounce  of  cubebs. 
Eleventh,  i  ounce  of  myrrh.  Twelfth,  i  ounce  of  cam- 
phor. Thirteenth,  i  ounce  of  boletus  laricis,  which  is  a 
purgative  comparable  to  jalap  and  senna. 

To  sum  up,  in  each  ounce  of  Warburg's  tincture  we 
have  about  ten  grains  of  quinine ;  fourteen  of  aloes;  four 
of  rhubarb  ;  one  of  opium  ;  two  of  elecampane  ;  two  of 
saffron ;  one  of  gentian ;  one  of  ginger ;  two  of  fennel 
seeds  ;  one  of  cubebs  ;  one  of  myrrh  ;  one  of  camphor  ; 
and  one  of  boletus  or  jalap  or  senna. 

In  building  up  his  tincture  Warburg  probably  took  a 
hint  from  the  German  and  French  so-called  Paracelsian 
elixir  of  life,  which  is  composed  of  aloes,  nine  parts ; 
gentian,  rhubarb,  zedoary,  saffron,  and  boletus  laricis,  or 
larch,  or  purging  agaric,  each  one  part ;  digested  in  proof 
spirit  two  hundred  parts,  and  of  wliich  the  tonic  and 
alterative  dose  is  one  or  two  drachms. 

The  European  tincture  of  rhubarb  is  made  with  carda- 
mom and  coriander  seeds,  and  safiron.  The  angelica 
seeds,  fennel  seeds,  elecampane,  saffron,  zedoary,  cubebs, 
and  the  little  mjrrhand  camphor  are  pleasant  aromatic  ad- 
ditions to  the  tincture  ;  and  the  one  grain  of  gentian,  and 
one  grain  of  boletus  or  jalap  do  not  deserve  a  great  deal 
of  attention. 

The  question  arises  whether  a  few  aloes  and  rhubarb 
pQls  with  quinine  and  spices  will  not  accomplish  almost  all 
that  Warburg's  tincture  will. 


64 


THE  MEDICAL  RECORD. 


[July  19,  1884. 


Or  if  a  liquid  preparation  is  preferred  any  physician 
can  build  a  formula  for  himself  with  simple  tincture  of 
aloes  and  liquorice,  U.  S.  P. ;  tincture  of  rhubarb  and  car- 
damoms, U.  S.  P. ;  or  tinct.  rhei  et  sennae,  U.  S.  P., 
made  with  rhubarb,  senna,  coriander  and  fennel  seeds 
aided  by  a  little  paregoric  and  compound  tincture  of  gentian 
— the  latter  made  with  gentian,  bitter  orange  peel  and 
coriander  seeds — which  will  complete  the  whole,  unless 
one  prefers  to  add  a  few  drops  of  tincture  of  myrrh  and 
fluid  extract  of  cubebs. 


DELIRIUM  CLOSELY  RESEMBLING  MANIA  A 
POTU,  FOLLOWING  THE  FREE  USE  OF 
MORPHINE. 

By  S.  W.  DANA,  M.D., 

NBW  YORK. 

The  patient,  a  youth  of  seventeen,  of  good  constitution 
and  temperate  habits,  during  an  attack  of  acute  perito- 
nitis lasting  seven  days  took  morphine  from  two  to  nearly 
six  grains  daily — about  twenty-eight  grains  in  all.  Dur- 
ing the  first  four  days  his  mind  remained  clear  and  active, 
though  the  morphine  given  was  sufficient  to  reduce  his 
respirations  to  twelve  per  minute.  There  were  brief 
periods  of  sleep,  not  amounting  to  more  than  three  or 
four  hours  in  twenty-four.  During  the  last  three  days 
there  was  much  less  sleep  and  occasional  light  delirium. 
After  the  morphine  was  discontinued  the  delirium  grad- 
ually assumed  most  of  the  characteristic  features  of  de^ 
lirium  tremens  and  continued  three  days.  During  this 
time  insomnia  was  absolute.  The  patient  had  delusions 
of  hearing  and  sight ;  heard  imaginary  persons  calling 
out  to  him ;  described  their  appearance  and  repealed 
their  words;  often  fixed  his  eyes  upon  and  clutched  at 
imaginary  objects  in  the  air ;  was  in  constant  movement 
and  made  frequent  attempts  to  get  out  of  bed ;  had  im- 
portant matters  to  attend  to,  and  felt  injured  in  being 
restrained.  The  pupils  of  his  eyes  were  rather  wildly 
dilated. 

Meanwhile  the  general  condition  of  the  patient  was 
otherwise  good.  His  pulse  and  temperature  were  nor- 
mal. He  took  a  half  pint  of  milk  every  three  hours,  and 
had  a  perfectly  natural  action  of  the  bowels  every  day. 
Abdominal  tension  and  tympanitis  were  rapidly  disap- 
pearing, and  convalescence  from  the  peritonitis  was  pro- 
gressing favorably.  Under  these  circumstances  I  re- 
frained from  medication,  confidently  expecting  that 
natural  sleep  would  soon  supervene.  When,  however, 
the  delirium  had  continued  three  days  with  no  indication 
of  abatement,  I  prescribed,  with  the  view  of  procuring 
sleep,  the  following  potion  : 

J     9.  Potass,  bromid 3  ss. 

Chloral  hydrat. grs.  xv. 

Morph.  sulphat gr.  | 

Aqua q.  8.     M. 

Twenty  minutes  after  taking  this  dose  the  patient  fell 
into  a  quiet  sleep,  which  continued  sixteen  hours,  save 
momentary  interruptions  every  three  hours,  when  nour- 
ishment was  given.  At  the  end  of  his  sixteen-hour  nap 
the  patient  awoke  cheerful  and  sane.  His  subsequent 
convalescence  was  rapid,  and  there  was  no  further  de- 
lirium. 

Two  symptoms  usually  met  with  in  delirium  tremens 
were  not  present  in  this  case,  namely,  anorexia  and 
muscular  tremor. 


Tetanus  following  Heaton's  Method  for  the 
Cure  of  Hernia.— The  editor  of  the  Peoria  Medical 
Monthly  states  that  two  patients  who  were  recently 
operated  upon  by  the  Heatonian  method  died  a  few  days 
afterward  from  tetanus.  A  third  patient  suffered  severely 
from  an  extensive  phlegmonous  inflammation  of  the  whole 
lower  limb. 


THE  INHALATION  OF  SULPHURIC  ETHER 
WITH  A  DESCRIPTION  OF  AN  AUTOMATIC- 
SUPPLYING  INHALER. 

By  FRANZ  HEUEL,  Jr.,  M.D., 

SURGBON  TO  THB  OTY  HOSPITALS  ON  RANDALL'S  ISLAND,  PROSKCTOR  TO  THR 
CHAIR  OP  SURGKRY  AND  INSTRUCTOR  IN  OPBRATIVR  SUKGRRY  IN  THS  MXDICAL 
DBPARTMRNT  OP  THR  UNIVERSITY  OP  THB  CITY  OP  NSW  YORK. 

The  administration  of  anaesthetic  vapors  in  graduated 
quantities  and  controllable  by  the  operator  has,  for  years, 
been  a  matter  of  investigation  and  study  by  the  medical 
profession.  Many  forms  of  apparatus  have  been  devised 
to  accomplish  this  end,  but  the  majority,  while  promis- 
ing much  in  theory,  fail,  in  practice,  to  answer  all  of  the 
requirements  which  an  instrument  of  this  class  should 
possess.  Among  the  principal  objections  to  these  differ- 
ent forms  of  apparatus  may  be  enumerated  that  of  the 
unsatisfactory  distribution  of  the  anaesthetic  fluid,  giving 
rise  to  disagreeable  and,  sometimes,  disastrous  accidents ; 
and  the  imperfect  working  of  valves,  obstructing  free  res- 
piration and  thereby  rather  asphyxiating  than  anaesthe- 
tizing the  patient.  Another  objection  is  the  difficulty 
which  attends  their  thorough  cleansing,  a  matter  of  some 
weight  in  these  days  of  asepsis.  Aside  from  which,  if 
there  is  anything  that  will  disgust  a  patient  at  the  com- 
mencement of  the  administration  of  ether,  it  is  an  appa- 
ratus impregnated  with  the  odor  of  vomited  or  expecto- 
rated matters.  Finally,  the  intricacy  of  their  construction 
often  renders  their  management  difficult,  increases  their 
expense,  and,  in  a  great  many  instances,  adds  to  their 
bulk  and  difficulty  of  transportation. 

For  ordinary  use  nothing  to  date  has  been  found  bet- 
ter than  the  simple  napkin  or  towel  folded  in  the  form  of 
a  cylinder  or  cone  and  having  incorporated  between  its 
folds  a  piece  of  paper  to  give  it  the  requisite  amount  of 
stiffifiess,  thereby  preventing  the  inhaler,  when  saturated 
with  ether,  from  collapsing  upon  the  face  of  the  patient 
and  excluding  all  air.  Gross  ignorance  or  criminal  care- 
lessness on  the  part  of  the  administrator  during  inhala- 
tion may  produce  death  by  asphyxia,  owing  to  the  use  of 
an  ill-adjusted  apparatus  or  the  crowding  upon  the  face 
of  towels  saturated  with  ether  so  that  the  patient  is  de- 
prived of  all  air.  Such  accidents,  however,  must  be 
exceedingly  rare.  As  a  fresh  napkin  or  towel  should 
always  be  used  for  each  case,  the  cone  will  always  be 
in  a  cleanly  condition.  This  is  more  than  can  be  said 
of  a  good  many  face-pieces  where  inhalers  are  employed. 
The  too  frequent  removal  from  the  face  of  the  cone,  for 
the  purpose  of  replenishing  the  anaesthetic,  may  be 
avoided  by  placing  a  sponge,  handkerchief^  or  piece  of 
lint  in  the  top  of  the  cone  to  be  saturated  with  ether. 
When  additional  ether  is  necessary  it  should  be  poured 
into  the  inverted  cone  as  quickly  as  possible,  since  a  few 
inhalations  of  pure  air  will  neutralize,  to  a  considerable 
extent,  the  anaesthetic  effect  already  obtained.  As  has 
been  aptly  remarked  by  Dr.  J.  B.  Roberts,^  ether,  in 
order  to  be  properly  administered,  should  be  given  in 
large  quantities  and  with  little  air,  while  chloroform 
should  be  given  in  small  quantities  and  with  much  air, 
otherwise  the  stage  of  excitement  will  not  be  overcome 
without  considerable  trouble  and  loss  of  valuable  time  ; 
in  fact,  might  lead  the  administrator  to  think  the  patient 
could  not  be  fully  etherized.  A  widely  prevalent  idea  is 
that  ether  should  be  given  with  much  air.  In  speaking  of 
this  as  the  ''Ether  Folly ;'  Dr.  J.  B.  Roberts  says  it  "is 
almost  universal.  Often  have  I  heard  physicians  say  of 
a  patient,  '  He  couldn't  be  etherized ;  I  had  to  give  him 
chloroform.'  Now,  the  fault  was  not  with  the  patient, 
but  with  the  doctor.  I  doubt  there  being  an  individual 
or  an  animal  in  the  world  that  cannot  be  anaesthetized 
with  ether  properly  administered.  ...  I  do  not 
advocate  giving  ether  carelessly,  but  I  assert  that  it  is 
usually  given  inefficiently.  More  danger  is  to  be  found 
in  this  long-continued  inefficient  etherization  than  in  the 
prompt  method  I  describe." 

>  Philadelphia  Polyclinic,  February  15,  1884. 


July  19.  ig^4-3 


THE  MEDICAL  RECORD. 


65 


1%e  amount  of  vapor  inhaled  can  be  easily  regulated 
]« removing  the  cone  a  short  distance  from  the  patient's 
^e  and  allowing  him  an  admixture  of  atmospheric  air 
fphea  necessary,  looking  to  its  physiological  effects  rather 
t^ga  any  arbitrary  rules  relative  to.  an  admixture  with 
atiBOspheric  air.  Too  great  concentration  of  vapor  need 
inrdij  be  guarded  against,  as  experience  has  taught  us 
the  comparative  safety  of  inhalation  of  sulphuric  ether. 

A  simple  napkin  or  towel,  therefore,  will  answer  the  pur- 
pose, and  either  is  as  safe  as  any  inhaler  can  be,  although 
I)Oth  have  their  objections,  diief  among  which  is  the 
^e  waste  of  ether  consequent  upon  their  use,  especially 
in  a  warm  room,  as  only  a  small  quantity  of  the  vapor 
^en  off  can  ever  be  inhaled ;  the  larger  part  escapes 
^  the  side  of  the  cone,  enters  the  apartment,  and  inter- 
ieres  with  the  oomfort  of  the  surgeon  and  his  assistants. 

Hence,  in  constructing  an  apparatus  for  ether  inhala- 
tion, the  objects  to  be  attained  are,  first,  that  it  be  more 
cofivenient,  durable,  and  economical,  though  just  as 
ample,  easily  managed,  safe,  and  cleanly  as  the  towel 
cone;  second,  that  it  present  no  possible  difficulty  to 
(ree  respiration  either  by  the  inadequate  diameter  of  its 
res|niatory  passages,  or  by  inhaling  or  exhaling  valves, 
rhich  are  apt  to  get  out  of  order  ;  third,  that  it  be  self- 
sappljiBg,  with  tihe  anaesthetic  under  perfect  control, 
thereby  avoiding  the. necessity  of  removing  the  instru- 
ment from  the  face  to  replenish  with  ether  ;  fourth,  that 
it  present  the  air  as  nearly  as  possible  saturated  with 
ether,  at  die  same  time  preventing  its  general  diffusion 
outside  of  the  body  without  impeding  the  patient's  res- 
jiratioD;  and,  lastly,  that  it  be  inexpensive,  and  not 
bulky  or  cumbersome. 


To  attain  these  desiderata  I  have  devised  an  inhaler, 
coostmcted  for  me  by  Messrs.  Tiemann  &  Co.,  of  this 
etf,  which  overcomes  in  a  satisfactory  manner  all  of 
&e  difficulties  enumerated  above.  I  have  used  it  in 
lospita]  and  private  practice  for  the  last  nine  months, 
ad  have  found  that  it  practically  fulfils  the  theoretical 
nqmrements  of  a  perfect  inhaler. 

It  is  constructed  of  thin  nickel-plated  brass,  with  a 
tliber  £u:e-piece,  ^d  is,  when  closed  for  transportation, 
i  cylinder  six  inches  long  by  three  inches  in  diameter, 
io^  of  convenient  size  to  carry  in  the  pocket,  andcon- 
Ms»  as  shown  in  the  accompanying  woodcut,  Fi^.  i,  of 
iiee  parts,  viz. :  An  ether  reservoir,  a ;  a.  respiratory 
Aunber,  ^  /  and  a  face-piece,  ^,  one  placed  below  the 
Ifcei. 

Ihe  ether  reservoir  is  cylindrical  in  shape,  holding 
Asftt  twelve  fluid  ounces..    It  has  at  the  top,  near  the 


aide,  an  opening,  </,  closed  by  a  screw-cap  and  rubber 
washer  for  filling  the  reservoir.  The  screw-cap  has 
drilled  through  its  side,  below  the  washer,  a  small  open- 
ing, so  that  when  unscrewed,  before  using  the  apparatus, 
by  a  few  turns  it  will  permit  air  to  enter  the  ether  reser- 
voir to  supply  the  vacuum  left  by  the  exit  of  ether 
through  the  stop-cock  at  the  bottom. 

At  the  bottom  of  the  ether  reservoir,  near  the  side,  is 
an  opening  closed  by  a  metal  stop  cock,  e,  continuous 
with  which,  and  in  a  plane  parallel  to  and  one  half-inch 
below  the  bottom,  is  a  spiral  coil,  /,  of  small  copper  tubing, 
having  perforations  about  one  inch  apart  on  the  top  or 
side  nearest  the  reservoir.  This  pipe  runs  from  the 
stop-cock  on  the  side  straight  to  the  centre,  and  then 
spirally  toward  the  periphery.  To  steady  it,  it  is  soldered 
at  its  outer  margins  to  a  ring,  ^,  projecting  from  the  bot- 
tom of  the  reservoir.  The  stop-cock  has  attached  to  it 
an  index  hand  and  chequered  button,  ^,  which  moves 
on  the  outside  of  the  reservoir,  and  indicates  when  par- 
allel to  the  long  axis  of  the  reservoir  that  it  is  closed,  J  / 
when  moved  away  from  this  axis  toward  ^,  that  it  is 
being  opened.  The  ring  ^,  projecting  from  the  bottom 
of  the  reservoir,  fits,  by  an  accurate  bayonet  joint,  into 
the  top  of  the  next  cylinder,  d,  which  is  the  respiratory 
chamber.  Both  the  ring  g^  and  the  top  of  the  respira- 
tory chamber  are  pierced  with  corresponding  holes  five- 
sixteenths  of  an  inch  in  diameter  and  about  three-eighths 
of  an  inch  apart.  These  I  will  designate  as  the  respira- 
tory openings.  The  bottom  of  the  respiratory  chamber 
is  slightly  turned  in,  forming  a  shoulder  upon  which  is 
fitted  a  disk  of  wire  ^auze,  li,  to  retain  the  evaporating 
medium  and  protect  it  from  expectorated  and  vomited 
matter.  Around  the  outside  of  the  respiratory  chamber, 
and  one-half  inch  from  the  bottom,  is  soldered  a  piece  of 
brass  wire,  /,  to  act  as  a  shoulder  to  the  top  of  the  rub- 
ber face-piece,  r,  which  fits  over  the  bottom  of  the  res- 
piratory cylinder.  Within  the  respiratory  chamber  and 
upon  the  wire  gauze  is  packed  washed  sheep's  wool, 
"  which  I  have  found  the  best  medium  of  evaporation  for 
the  ether,  which  drops  upon  it  from  the  spiral  coil  above. 
Now  it  will  be  seen  why  the  perforations  in  the  copper 
coil  are  placed  in  the  upper  side,  as  the  ether,  when  the 
inhaler  is  placed  in  the  vertical  position  for  use,  must 
first  fill  the  entire  coil  before  it  can  escape  from  the 
openings,  thereby  ensuring  an  equal  distribution  of  the 
anaesthetic  fluid  For  the  same  reason  the  coil  is  first 
run  straight  from  the  stop-cock  to  the  centre  of  the  ether 
reservoir,  and  then  spirally  to  its  periphery,  as  the  in- 
haler, when  in  use,  cannot  always  be  kept  in  a  strictly 
vertical  position. 

The  face-piece,  ^,  is  made  of  soft  vulcanized  rubber, 
shaped  like  a  truncated  cone,  with  notches  for  the  chin, 
»i,  and  nose,  n,  to  more  accurately  fit  it  to  the  face. 
Being  made  of  soft  rubber,  it  adapts  itself  equally  well  to 
a  round,  thin,  large,  or  small  face,  a  prominent  or  a  flat 
nose.  It  will  answer  as  well  for  a  child  as  for  an  adult. 
In  the  former  the  chin  must  be  placed  within  the  face- 
piece,  the  rubber  then  covering  the  nostrils,  mouth,  and 
entire  chin.  In  the  latter  a  notch,  m,  in  the  rubber  fits 
on  the  \:hin.  At  the  top,  and  within  the  face-piece,  a 
metal  ring,  /,  is  baked  on,  which  firmly  fits  over  the 
bottom,  ^,  of  the  respiratory  chamber. 

In  the  use  of  the  inhaler,  as  with  any  other  appliance 
for  the  administration  of  anesthetics,  the  following  points 
should  be  observed : 

The  patient  is  first  prepared  by  loosening  the  clothing 
about  the  neck  and  waist,  so  that  there  shall  be  no  ob- 
struction to  respiration  or  circulation.  The  part  to  be 
operated  upon  is  then  made  freely  accessible.  Should 
the  patient  have  any  artificial  teeth  they  must  be  removed, 
in  order  to  guard  against  their  entering  the  respiratory 
passages  or  being  swallowed.  The  assistant  having 
charge  of  the  etherization  should  place  the  patient  supme 
upon  the  operating  table  or  bed,  with  the  head  slightly 
raised  upon  a  pillow,  and  should  stand  at  the  head  o 
the  bed.     He  should  have  within  easy  reach  his  inhalei 


^  \ 


66 


THE  MEDICAL  BLECORD. 


[J%  I9i  18844 


and  a  dressing  forceps,  with  which  to  draw  out  the  tongue 
should  it  fall  back  and  cause  closure  of  the  glottis ;  or,  if 
necessary,  to  remove  pieces  of  egested  matter.  He 
should  also  be  provided  with  a  hypodermic  syringe  charged 
with  brandy,  whiskey,  or  diluted  aqua  ammonia,  to  use  in 
case  the  pulse  becomes  feeble.  A  basin  and  towels  will 
be  necessary,  in  case  the  patient  should  vomit  or  expec- 
torate. The  assistant  administering  the  ether  should  pay 
strict  attention  to  the  duties  incumbent  upon  him,  to  the 
exclusion  of  even  momentarily  transferring  his  thoughts 
to  the  operation,  or  what  may  be  going  on  in  or  about 
the  room. 

Everything  being  in  readiness  the  inhaler,  with  the 
stop-cock  still  closed,  is  placed  vertically  over  the  pa- 
tient's mouth  and  nose.  It  should  be  supported  in  this 
position  by  placing  one  hand  on  either  side  of  the  pa- 
tient's face  so  that  in  case  of  necessity  the  movements 
of  the  head  may  be  restrained  Occupying  this  position 
the  administrator  can  easily  determine  the  condition  of 
the  pulse  from  an  examination  of  the  carotid,  facial,  or 
temporal  arteries.  In  a  few  encouraging  words  the  pa^ 
tient  is  directed  to  "blow  out"  (exhale)  forcibly,  regu- 
larly, and  to  continue  to  do  so  as  long  as  he  can 
remember.  The  rubber  fitting  the  face  very  closely  the 
patient  will  necessarily  be  compelled  to  breathe  through 
the  sheep's  wool  and  openings  in  the  respiratory  cham- 
ber, but  neither  of  these  impede  in  the  least  free  and 
natural  respiration.  Hence  the  feeling  of  apprehension 
and  sense  of  suffocation  which  usually  disturbs  him  at  this 
time  when  any  of  the  ordinary  inhalers  are  used  is,  to  a 
large  extent,  avoided.  I  direct  the  patient  to  **blow 
out "  because  I  have  found  this  a  much  better  plan  with 
the  average  person  than  to  request  him  to  inspire  deeply, 
as  it  is  more  easily  comprehended  and  he  will  be  obliged 
to  take  a  deep  inspiration  as  a  necessary  result  of  a  long 
exhalation,  thereby  getting  more  of  the  anaesthetic  and 
sooner  coming  under  its  elects. 

After  the  patient  has  made  a  few  respirations  in  this 
manner  the  stop-cock  of  the  ether  reservoir  is  turned  on 
by  the  thumb  of  either  hand  supporting  the  inhaler  on 
the  face,  permitting  only  a  few  drops  of  ether  to  flow  in 
to  the  absorbent  material  in  the  respiratory  chamber,  so 
as  to  gradually  accustom  the  larynx  to  it.  In  this  man- 
ner, and  at  short  intervals,  more  ether  should  be  added 
until  the  full  anaesthetic  effect  is  obtained.  Having 
reached  this  point  it  will  be  found  that  a  much  smaller 
quantity  will  answer  to  maintain  its  effect  than  usual. 
After  being  applied,  the  apparatus  should  not  again  be 
removed  from  the  face,  unless  an  urgent  necessity  de- 
mands it ;  otherwise  the  patient,  by  breathing  pure  air, 
would  neutralize  to  a  certain  extent  the  effect  of  the 
ether  already  given,  and  thereby  necessarily  prolong  its 
administration. 

Care  should  be  taken  not  to  oversaturate  the  material 
in  the  respiratory  chamber,  lest  the  ether  might  flow  over 
the  patient's  face.  By  the  exercise  of  a  little  caution 
this  can  easily  be  avoided. 

Sometimes,  during  semi-consciousness,  when  a  patient 
forgets  or  refuses  to  exhale  regularly,  the  respirations 
may  be  stimulated  by  asking  him  questions,  asking  him 
to  count  from  one  to  fifty,  or  to  say  his  ABC.  Again, 
if  the  administrator  will  endeavor  to  guide  the  person's 
thoughts  into  agreeable  channels,  from  the  commence- 
ment of  the  etherization,  by  conversing  with  him  on 
pleasant  and  familiar  subjects,  it  will  often  have  the  effect 
of  inducing  pleasant  dreams  for  the  patient  throughout 
the  employment  of  the  anaesthetic.  By  these  means  the 
patient  often  passes  under  the  effects  without  a  struggle 
or  beine  in  the  least  alarmed. 

Should  it  become  necessary,  after  anaesthesia  is  induced, 
to  turn  the  patient  on  his  side,  the  ether  reservoir  may 
be  taken  off  and  the  respiratory  chamber  with  attached 
face-piece  only  used,  in  which  case  small  quantities  of 
ether  are  dropped  as  needed  from  the  supply  opening,  d, 
of  the  ether  reservoir  upon  the  absorbent  material  in  the 
respiratory  chamber.     To  prevent  a  too  free  diffusion  of 


the  vapor  about  the  room  the  supporting  hand  may  be 
placed  over  the  respiratory  chamber. 

After  using  the  inhaler,  the  face-piece  should  be  re- 
moved and  thoroughly  cleaned  by  placing  it  in  water;  the 
sheep's  wool,  if  desired,  can  be  washed  to  free  it  from 
the  products  of  respiration  and  then  dried  to  be  used 
again ;  but  it  is  better  to  throw  it  away,  as  it  is  very  cheap, 
and  use  new,  fresh  wool  for  each  case.<|| 

The  apparatus  can  now  be  put  together  for  trans- 
portation, by  reversing  the  face-piece  (see  Fig.  2)  over 
the  respiratory  chamber  and  placing  over  the  bottom  the 
metal  cap,  r,  which  accompanies  the  apparatus. 

From  time  to  time  it  is  well  to  put  a  drop  of  oil  on  the 
stop-cock  of  the  reservoir,  as  the  ether  dissolves  out  the 
oil  and  makes  the  stop-cock  turn  with  difficulty. 

"^vagvess  of  ptjedical  Siciencz. 

Simulation  of  Unilateral  Amaurosis. — ^To  discover 
simulation  of  one-sided  blindness.  Dr.  Bravais  recom- 
mends the  method  of  Snellen.  This  latter  rests  on  the 
fact  that  if  one  writes  with  a  red  pencil  on  paper,  the 
letters  written  cannot  be  recognized  if  seen  through  red 
glass.  If  one  holds  before  the  apparently  healthy  eye  a 
red  glass,  and  before  the  pretended  blind  eye  any  kind  of 
glass,  or  none  at  all,  and  requests  the  simulator  to  read 
the  red  letters  on  the  paper  (which  have  not  been  before 
shown  to  him),  and  he  can  read  them,  the  evidence  of  his 
simulating  is  clear ;  for  if  the  second  eye  had  really  been 
blind,  he  would  not  have  been  able  to  recognize  the  red 
letters  through  the  red  glass. — Medical  and  Surgical  Rt' 
porter^  May  31,  1884, 

Vinegar  in  Post-Partum  Hemorrhage. — Dr.  Grigg 
relates  in  the  British  Medical  Journal  the  case  of  a 
"  flooder  "  in  whom  a  profiise  hemorrhage  was  almost  in- 
stantaneously arrested  by  the  administration  of  vinegar. 
The  uterus,  which  was  flaccid  and  gradually  dilating,  con- 
tracted at  once  after  the  patient  had  been  given  a  wine- 
glassful  of  vinegar,  and  after  the  second  dose  of  the  acid 
the  hemorrhage  ceased  entirely.  He  states  that  the 
pupil  midwives  are  accustomed  to  give  this  remedy  in 
preference  to  ergot,  as  its  action  is  more  rapid  and  cer- 
tain. So  rapid,  indeed,  he  asserts,  is  its  action,  that  he 
counsels  against  its  use  until  after  the  expulsion  of  the 
placenta,  for  fear  of  causing  a  retention  of  that  body. 

The  Treatment  or  Phthisis  by  Overfeeding.-^ 
Drs.  Broca  and  Wins  believe  with  Debove  that  anorexia 
is  one  of  the  chief  causes  of  exhaustion  in  phthisis,  and 
that  a  systematic  overfeeding  of  consumptive  patients 
by  means  of  the  stomach-tube  exercises  a  most  bene- 
ficial influence  on  the  disease  itself.  Nitrogenous  food  is 
thebest,  especially  milk,  eggs,  and  meat-powder.  The 
quantity  introduced  into  the  stomach  at  a  time  must 
never  exceed  one  litre.  In  most  cases  the  food  was  well 
digested,  the  perspiration,  cough,  and  dyspnoea  dimin- 
ished, and  the  patient  increased  in  weight.  In  several 
cases  the  signs  of  excavation  in  the  lungs  became  less 
distinct,  though  they  never  disappeared  entirely. — I^ 
France  MhdicaU. 

Contraindications  in  the  Use  of  Quinine. — Dr. 
Rabuteau  has  observed  several  cases  in  which  nausea, 
vomiting,  and  pain  in  the  stomach  were  caused  by  the 
administration  of  iodide  of  potassium  and  sulphate  of 
quinine  in  combination.  He  cautions  against  the  simul- 
taneous administration  of  these  drugs,  and  believes  that 
the  unpleasant  symptoms  were  due  to  the  setting  free  of 
pure  iodide.  He  further  asserts  that  quinine  is  con- 
traindicated  in  women  during  menstruation.  He  cites 
instances  in  which  women,  who  at  other  times  showed 
no  idiosyncrasy  in  this  respect,  were  imable  to  take 
quinine  while  menstruating,  because  of  the  intense  hypo- 
gastric pain  which  invariably  followed. — Allgemetne 
Medicinische  Ceniral'2^eitung^  May  17,  1884. 


July  19,  1884.] 


THE  MEDICAL  RECORD. 


67 


Herkpitary  Ataxia. — Dr.  Lucas  Championni^re  de- 
scHbes  this  afifection,  also  called  Friedreich's  disease, 
wiu'cb  partakes  of  the  characteristics  of  both  multiple 
spinal  sclerosis  and  progressive  locomotor  ataxia.  It 
makes  its  appearance  in  childhood  or  in  youth,  thus  dif- 
fering from  ataxia  proper,  which  occurs  during  the  second 
period  of  life.  Like  both  the  diseases  which  it  resembles, 
Friedreich's  disease  usually  occurs  in  individuals  who  are 
affected  with  some  form  of  nervous  disease,  as  hysteria, 
epOepsy,  general  paralysis,  etc.  Its  peculiar  feature  is 
that  it  may  attack  several  children  in  the  same  fieunily. 
As  yet  it  has  been  observed  only  a  few  times,  Friedreich 
himself  having  seen  but  nine  cases,  in  three  fiunilies.  An 
English  writer  has  seen  five  children,  in  a  family  of  nine, 
who  suffered  with  it  Its  course  is  regularly  progressive 
to  a  fatal  issue,  again  resembling  ataxia  proper.  As  to 
the  lightning-pains,  and  habitual  anaesthesia  or  hyperaes- 
diesia  in  spots  which  occur  in  locomotor  ataxia,  these  are 
wanting  in  hereditary  ataxia ;  but  there  are  present  motor 
inco-ordination  to  an  exaggerated  degree,  and  impaired 
or  abolished  reflexes.  Like  multiple  spinal  sclerosis,  this 
disease  exhibits  nystagmus,  paralysis  as  to  associated 
ocular  movements,  and  disturbances  of  speech,  while 
paralytic  myosis  and  blindness  are  absent.  There  is  also 
an  absence  of  the  bladder  troubles,  which  are  so  fre- 
qoently  seen  in  locomotor  ataxia,  as  well  as  of  the  gastric 
and  laryngeal  crises,  and  trophic  disturbances.  It  will 
duis  be  seen  that  this  disease  resembles  true  ataxia  in  re- 
spect to  the  spinal  symptoms,  while  it  presents  charac- 
teristics which  prevent  mistaking  it  for  multiple  spinal 
sclerosis.  The  anatomical  lesion  is  located  in  the  pos- 
terior columns  and  lateral  fasciculi,  which  explains  the 
clinical  resemblance  to  both  of  the  diseases  with  which 
hereditary  ataxia  has  been  compared. — Archives  of  Pe- 
£airuSf  May  15^  1884. 

Multiple  Spinal  Arthropathies. — Dr.  J.  Boyer  re* 
ports  in  Lyon  M^ical  of  June  i,  1884,  the  case  of  an 
ataxic,  forty-five  years  of  age,  in  whom  the  trophic  dis- 
turbances were  an  early  symptom  and  occurred  several 
jears  before  inco-ordination  of  movement  was  marked. 
The  joint  troubles  were  manifested  first  by  a  spontaneous 
loxation  of  the  hip,  then  the  knees  became  swollen,  and 
inally  both  feet  became  also  swollen.  The  tumefaction 
of  the  feet  was  at  first  oedematous,  and  later  became  of  a 
kffd  osseous  consistency,  most  marked  on  the  dorsal 
surface.  The  lesions  in  the  feet  were  found  after  death 
to  consist  in  an  cedematous  infiltration  of  the  soft  parts 
of  the  tarsal  and  metatarsal  regions,  marked  hypertrophy 
of  the  head  of  the  astragalus,  of  the  os  calcis,  and  of  the 
scaphoid  bone.  At  the  tarso-metatarsal  joint  there  was 
a  complete  union  of  the  cuboid  and  three  cuneiform  with 
tbe  metatarsal  bones,  with  hypertrophy,  softening,  fria^ 
bOity,  and  spongy  degeneration  of  the  anchylosed  articular 
saifaces.  Artlu-opathies  of  the  feet  in  locomotor  ataxia 
are  of  comparatively  rare  occurrence,  yet,  as  has  been 
^wn  by  Boyer,  Page,  Charcot,  and  F^r6,  are  not  so  in- 
frequent as  was  formerly  supposed. 

The  Diagnostic  Value  of  Certain  Symptoms  in 
THE  Diseases  of  Children. — Professor  S.  M.  Politzer 
formulates  the  following  concerning  the  significance  of 
indiridual  symptoms  in  children's  diseases  {Deutsche 
Mdicinal-Zeitung,  May  19,  1884)  :  i.  The  sjrmptom  of 
a  strongly-marked  nasal  tone  in  crying  points  to  the 
probable  existence  of  a  retropharyngeal  abscess.  2.  A 
Inid  and  very  long-continued  expiratory  sound,  with 
nnnal  mspiration  and  the  absence  of  dyspnoea,  is  signifi- 
cant of  chorea  major.  Sometimes  this  sound  resembles 
(be  bellowing  of  an  animal,  and  may  continue  for  a  long 
time  as  the  only  symptom  of  chorea.  3.  A  thoracic, 
i^^g  inspiration  indicates  cardiac  weakness.  This  is 
ooe  of  the  hrst  symptoms,  appearing  before  cyanosis  or 
pllor  of  the  face,  thready  pulse,  coldness  of  the  extrem- 
ftes,  or  the  other  well-recognized  signs  of  weak  heart. 
4-  A  marked  diaphragmatic  expiration,  accompanied  with 
a  fine,  high-pitched  whistling,  points  to  bronchial  asthma. 


5.  A  marked  interval  between  the  end  of  expiration  and 
the  beginning  of  inspiration  renders  the  diagnosis  of 
catarrhal  Iar3mgiti8  without  exudation  probable.  6. 
There  is  no  special  significance  in  the  loud,  sort  of  bleat* 
ing,  expiratory  sound  sometimes  observed  in  infants  dur- 
ing the  first  months  of  life.  It  seems  to  depend  upon  a 
modified  innervation  within  physiological  limits,  and  re- 
sembles the  want  of  rhythm  in  the  cardiac  movements 
occasionally  met  with  in  the  early  years  of  childhood. 
The  following  symptoms  are  given  by  the  author  as  of 
value  in  the  early  diagnosis  of  cerebral  diseases  :  i.  A 
peculiar  drowsiness,  continuing  for  several  da^s,  unac- 
companied by  fever  or  other  disturbance,  is  indicative  of 
basilar  meningitis.  This  is  a  more  valuable  sign  than 
headache,  vomiting,  or  a  slow,  irregular  pulse,  since  the 
latter  may  occur  in  various  extracranial  diseases.  2.  A 
tense,  elevated  anterior  fontanelle  points  to  intracranial 
effusion.  If  it  be  very  prominent,  resistant  to  pressure, 
and  without  a  sign  of  pulsation,  there  is  almost  certainly 
an  intermeningeal  hemorrhage.  A  deeply-sunken  fon- 
tanelle indicates  inanition  and  a  diminished  volume  of 
blood.  3.  Very  slow  movements  of  the  eyes,  followed  by 
fixity  in  one  position,  a  vacant  stare,  and  a  peculiar  lazy 
closing  of  the  lids  are  signs  of  a  beginning  basilar  menin- 
gitis. The  character  of  the  cry  is  of  value  sometimes  in 
the  diagnosis,  i.  A  fit  of  shrill  crying,  lasting  for  two  or 
three  minutes,  accompanied  by  an  expression  of  fear  in 
the  face,  and-coming  on  regulariy  an  hour  or  an  hour  and 
a  half  after  the  child  has  gone  to  sleep,  is  the  expression 
of  night-terrors.  Quinine,  given  in  rather  large  dose 
one  or  two  hours  before  bed-time,  is  an  effectual  remedy 
against  this  trouble.  2.  Periodical  crying-spells,  of  five 
or  ten  minutes'  duration,  commg  on  sometimes  during 
the  day  but  more  frequently  only  at  night,  point  to 
cramps  in  the  bladder,  provided  that  we  can  exclude  in- 
testinal or  gastric  colic.  This  is  speedily  cured  by  emul- 
sion of  lycopodium  with  or  without  belladonna.  3.  Cry- 
ing while  at  stool  and  an  evident  dread  of  the  act  of 
defecation  are  signs  pointing  to  fissure  of  the  anus.  4. 
Hard,  continuous  crying,  expressive  of  severe  pain,  to- 
gether with  firequent  putting  of  the  hands  to  the  head 
or  rolling  of  the  head  in  the  pillow,  are  evidences  of 
otitis  media  or  pain  in  the  ear  from  some  other  cause. 

5.  When  for  days  and  weeks  the  child  cries  on  being 
moved,  and  when  there  is  also  profiise  sweating  and  an 
elevated  temperature,  the  disease  is  rickets.  6.  Fre- 
quent crying,  with  habitual  sleeplessness  during  the 
first  two  years  of  life,  are  found  in  anaemic  and  poorly- 
nourished  children,  or  in  those  with  congenital  syphilb. 
Finally,  Professor  Politzer  recounts  some  other  single 
symptoms  which  aid  in  forming  a  speedy  diagnosis,  i. 
The  peculiar  physiognomy  of  children  suffering  from 
congenital  syphilis.  The  sinking  in  of  the  root  of  the 
nose,  the  sallow  complexion,  the  scanty  eyelashes,  the 
yellowish  edges  of  the  eyelids,  and  the  rhagades  on  the 
underlip  are  characteristic  of  hereditary  syphilis.  2. .  A 
falling  together  of  the  alae  nasi,  and  an  absence  of  all 
motion  in  them  during  inspiration,  point  to  hypertrophy 
of  the  tonsils.  3.  A  weakness  and  loss  of  motion  out  of 
all  proportion  to  the  gravity  or  duration  of  the  accom- 
panying illness  should  raise  a  suspicion  of  infantile  pa^ 
ralysis.  4.  A  partial  loss  of  hearing  after  a  sickness  is 
often  due  to  a  circumscribed  meningitis  at  the  base  of 
the  fourth  ventricle.  5.  Depression  of  the  mental  fac- 
ulties occurring  after  a  severe  infectious  disease  is  fre- 
quently indicative  of  a  beginning  acquired  idiocy. 
Strychnine  exerts  a  favorable  influence  in  these  cases. 

6.  Retarded  ossification  of  the  skull  may  imply  rachitis. 

7.  A  stiff  carriage  of  children  in  walking,  standing,  sit- 
ting down,  or  stooping,  is  observed  in  commencing  Pott's 
disease.  In  children  who  do  not  walk  there  is  a  painful 
contraction  of  the  features  when  they  are  lifted  up  or  set 
down.  8.  Constant  vomiting  of  all  ingesta,  lasting  for 
several  weeks,  in  children  with  large  heads  but  closed 
fontanelles,  is  a  sign  that  an  acute  hydrocephalus  is  en- 
grafted upon  the  chronic  condition. 


68 


THE  MEDICAL  RECORD. 


[July  19,  1884. 


The  Morbid  Anatomy  of  Malarial  Fever. — ^Vino- 
gradoff,  of  St.  Petersburg,  has  published  an  elaborate 
paper  on  this  subject,  based  on  his  extensive  experience 
in  Bulgaria  during  the  Russian-Turkish  war,  1877-78. 
Some  of  the  main  results  of  his  investigations  are  as 
follows:  Like  other  infectious  diseases,  malarial  fever 
manifests  itself  in  a  series  of  lesions  of  internal  organs. 
The  most  generally  spread  lesions  is  parenchymatous  in- 
flammation, which  affects  chiefly  the  liver,  spleen,  heart, 
and  kidneys,  but  occurs  also,  though  less  constantly  and 
in  a  less  considerable  degree,  in  the  lymphatic  glands, 
nerve-centres,  gastro-intestinal  and  sudoriferous  glands, 
testes,  and  striated  muscles.  The  parenchymatous 
changes  consist  mainly  in  opaque  swelling  o(  cellular 
elements,  with  their  subsequent  hyperplasia,  or  atrophy, 
or  degeneration.  In  the  liver  the  most  frequent  issue  of 
a  parenchymatous  inflammation  is  local  limited  atrophy 
(though  in  some  cases  there  occurs  a  diffuse  hyperplasia 
of  the  parenchyma,  as  Kelsch  and  Kl^ner's  observations 
show).  The  malarial  parenchymatous  inflammation  of 
the  kidneys,  in  a  certain  proportion  of  cases,  shows  a  ten- 
dency to  take  a  progressive  development  and  to  pass  into 
an  ordinary  form  of  Bright' s  disease.  The  parenchyma- 
tous alterations  in  the  heart  consist  in  slight  opacity  and 
swelling,  as  well  as  in  atrophy  and  brown  pigmentation 
of  muscle-cells.  The  parenchymatous  changes  in  the 
spleen  are  almost  exclusively  limited  to  the  lymphoid 
elements  of  the  pulp.  The  malarial  interstitial  inflam- 
matory process  is  spread  less  extensively  than  the  former, 
and  affects  mainly  the  liver,  spleen,  and  kidneys.  The 
interstitial  inflammation  of  the  liver  is  characterized  by 
the  development  of  older  fibrous  tissue  and  young  gran- 
ulation-structure. The  formation  of  the  new  interstitial 
tissue  is  not  spread  uniformly  all  over  the  organ,  but  is 
limited  to  certain  regions,  being  localized  mostly  in  the 
neighborhood  of  branches  of  the  portal  vein  and  between 
the  lobules.  In  the  spleen,  the  development  of  new  in- 
terstitial tissue  proceeds  along  the  veins  of  the  stroma ; 
Ihe  capsule,  also,  being  not  unfrequently  found  thick- 
ened In  the  kidneys  the  development  of  the  intersti- 
tial tissue  is  observed  both  in  the  cortical  and  in  the  me- 
dullary substances,  and,  as  in  other  organs,  is  of  a  diffuse 
character.  The  interstitial  changes  occur  also  in  the 
deep  muscular  layers  of  the  heart,  in  the  testes,  and  in  the 
lymphatic  glands,  especially  in  those  situated  within  the 
abdominal  cavity.  The  distribution  of  melanotic  pig- 
ment over  the  organs  is  connected  with  lesions  of  blood- 
vessels. The  vascular  changes  consist  at  first  in  swell- 
ing of  the  epithelioid  lining  of  the  capillaries,  which  may 
be  so  considerable  as  to  lead  to  complete  obliteration  of 
the  lumen  of  the  vessel.  Red  blood-corpuscles  become 
impacted  between  the  enlarged  epithelioid  cells,  and  are 
gradually  transformed  into  fine  granules  of  yellowish  and 
light-brown  coloring  matter.  The  latter  is  taken  up  by 
leucocytes  and  epithelioid  tissue.  The  epithelioid  cells 
undergo  either  proliferation,  or  fine  granular  disintegra- 
tion, leaving  then  heaps  of  pigment-granules  in  the  shape 
of  scales,  described  by  Frerichs  and  others.  Fatty  de- 
generation of  the  epithelioid  lining  of  the  capillaries  of 
the  brain  is,  according  to  the  author,  a  most  constant 
phenomenon  in  malaria,  and  is  especially  pronounced  in 
the  sites  of  extravasations.  Pigment-masses  are  accu- 
mulated mainly  in  the  spleen  ;  and  here  again  chiefly  in 
the  pulp,  interstitial  tissue,  and  vessels.  The  cells  of  the 
reticulum  undergo  partly  proliferation  with  subsequent 
transformation  into  fibrous  products,  partly  regressive 
modifications  (albuminous  and  fatty  degeneration).  In 
the  period  of  swelling  many  of  these  cells,  as  well  as 
large  lymphoid  elements,  absorb  blood-corpuscles,  which 
are  slowly  disintegrated  and  disappear,  leaving  light  and 
dark-brownish  pigment.  In  the  bone-marrow,  pigment 
is  mostly  found  in  the  stellated  cells  of  the  reticulum. 
The  pigment-masses  accumulated  in  the  liver  are  not 
formed  on  the  spot,  but  arrive  from  the  spleen  through 
the  vena  portse.  Two  main  sources  supplying  pigment 
in  melanaemia  are  the  spleen  and  the  bone-marrow.    Ac- 


cording; to  the  author,  this  fact  is  proved  by  the  occur- 
rence m  them  of  striking  phenomena  of  disintegration  of 
blood-corpuscles,  by  a  considerable  accumulation  in 
them  of  coloring  matter,  and  by  their  anatomical  ar- 
rangements allowing  pigment  to  easily  enter  into  the 
circulation.  Another  source  of  pigment-formation  is 
given  in  the  migration,  with  subsequent  disintegration,  of 
red  blood-corpuscles,  observed  in  the  brain.  When  dis- 
integrating,  some  of  the  blood-corpuscles  coalesce  and 
form  hyaline  or  diaphanous  bodies  or  scales,  identical 
with  those  found  by  Popoff  in  the  brain  of  uraemic  men 
and  of  uraemic  and  cholaemic  dogs.  Beside  the  liver, 
spleen,  bone-marrow,  and  brain,  the  author  observed 
deposition  of  coloring  matter  in  the  capillaries  of  the 
testes,  gastro-intestinal  mucous  membrane,  and  papillary 
layer  of  the  skin  :  in  the  lung  it  was  seen  in  the  intersti- 
tial tissue  and  epithelium  of  the  alveoli ;  in  the  lymphatic 
glands  it  was  present  chiefly  within  leucocytes.  As  to 
the  pigment  itself  found  in  malaria,  it  does  not  difier  in 
any  way  firom  that  derived  from  red  blood-corpuscles  in 
other  diseases. — London  Medical  Record^  June  16, 1884. 

Jequiritv  in  Persian  Practice. — A  Persian  physician 
stated  to  Dr.  Polak  that  jequirity  was  in  frequent  use  by 
the  oculists  in  his  country  in  the  treatment  of  pannus, 
corneal  opacities,  and  pterygium.  For  the  ensuing  in- 
flammation, usually  lasting  three  days,  they  used  local 
applications  of  milk,  decoction  of  althaea,  and  mucilage 
of  plantago  psyllium  (fleawort).  If  necessary,  the  treat- 
ment is  repeated  in  fifteen  or  sixteen  days,  but  never 
more  than  four  times  in  succession. — Ceniralblatt fur 
Praktische  AugenheilkundCy  May,  1884. 

Resection  of  Muscles  in  Infantile  Paralysis.— 
Mr.  Keetley  has  recently  undertaken  the  resection  of 
part  of  the  quadriceps  extensor  femoris  in  a  case  of  in- 
fantile paralysis  causing  inability  to   extend  the  right 
knee.      By  shortening  the  weak,  relaxed,  and  partly 
atrophied  muscle,  the  operator  hoped  to  increase  its 
strength,  with  the  aid  of  electricity  during  recovery  firom 
the  operation.      Mr.  Willett  has  already  resected  the 
tendo-Achillis  in  paralytic  talipes  calcaneus,  with  good 
results,  finding  that  the  shortening  of  the  abnormally 
elongated  tendon  enables  the  muscles  of  the  calf  to 
regain  some  portion  of  their  lost  functions,  especially 
when  the  muscular  wasting  has  been  chiefly  due  to  dis- 
ease, and  has  not  advanced  too  far.      Mr.   Keetley's 
patient  was  a  boy  aged  six,  who  had  suffered  from  pa- 
ralysis of  the  right  lower  extremity  for  four  years,  and 
the  muscular  atrophy  was  not  complete,  yet  sufficient  to 
prevent  thorough  extension  of  the  knee.     A  longitudinal 
incision  was  made  in   front  of  the  thigh,  about  three 
inches  in  length,  ending  an  inch  above  the  patella ;  the 
skin  was  held  apart  by  retractors,  and  one  inch  of  the 
entire  substance  of  the  quadriceps  was  cut  away  with 
scissors,   about    two  inches  above  the  patella.      The 
separated  ends  were  united  by  means  of  about   one 
dozen  carbolized  catgut-ligatures.     Esmarch's  bandage 
had  been  applied  before  operation,  and  only  one  small 
artery  required  ligature.     The  wound  was  dressed  with 
a  small  iodoform-pad  and  carbolic  gauze,  and  the  limb 
placed  on  a  back-splint  at  an  angle  of  sixty  degrees  with 
the  bed.     The  wound  healed  rapidly  and  perfectly,  but 
as  the  operation  was  performed  on  May  5th,  it  is  as  yet 
too  soon  to  determine  the  results  as  regards  the  function 
of  the  limb. — British  Medical  Journal^  May  31,  1884. 

Treatment  of  Furuncle. — ^The  following  treatment 
of  furuncles  is  highly  recommended  in  the  Revue  Mkdi 
cale  of  June  7,  1884.  The  boil  itself  and  the  inflamed 
zone  surrounding  it  are  covered  with  a  soft  paste  of  hone] 
and  powdered  arnica  flowers,  spread  upon  linen.  Thi 
application  is  renewed  every  two  hours  until  the  pain  an< 
soreness  have  entirely  disappeared,  which  they  do  by  th< 
second  or  third  day  at  the  latest.  If  the  application  i 
made  in  the  initial  stage,  the  boil  is  aborted  within  twenty 
four  hours. 


July  19, 1884.] 


THE  MEDICAL  RECORD. 


69 


False  Pregnancy. — Dr.  Delgado  reports  the  follow- 
ii}g  rather  remarkable  case,  of  spurious  pregnancy :  A 
woman,  aged   thirty,    married,   separated    accidentally 
from  her  husband  for  several  months,  presented  herself 
in  the  hospital  at  Valladolid  for  advice,  saying  that  she 
«as  pregnant  and  out  of  her  reckoning.     The  greater 
part  of  the  signs  of  pregnancy  existed — suppression  of 
the  menses  for  about  nine  months,  gradual  enlargement 
of  the  abdomen  to  full-term  size,  increase  of  the  breasts 
with  pigmentation  of  the  nipples,  vomiting  at  the  begin- 
ning and  end  of  the  pregnancy.     She  said  she  felt  the 
movement  of  the  child.     On  examination,  ballottement, 
movements  of  the  foetus,  and  foetal  heart-sounds  were 
absent    After  four  days  in  the  hospital,  labor-pains  be- 
pn,  temiinating  by  the  expulsion  of  a  great  quantity  of 
blood  in  dark  clots  and  liquid  by  the  vagina.     At  the 
same  time  there  was  violent  haematemesis,  which  had  to 
be  controlled  with  ice  and  perchloride  of  iron.     Three 
/ears  later,  when  she  had  again  been  living  with  her  hus- 
band for  eleven  months,  the  same  series  of  phenomena 
occurred ;  the  haematemesis,  however,  being  less  intense. 
On  the  most  careful  examination,  no  trace  of  mole,  or  of 
remains  of  placenta  or  foetal  membranes,  could  be  dis- 
covered. 

An  Instance  of  Nervous  iMPRESsroNABiLiTv. — Dr. 
filfiaerts  relates  a  curious  case  of  a  boy,  thirteen  years 
of  age,  who  resembled  Samson  in  that  the  cutting  of  his 
hair  exerted  an  extraordinary  influence  upon  him.  At 
the  first  dip  of  the  scissors  he  would  begin  to  tremble, 
then  he  would  suffer  from  ringing  in  the  ears,  vertigo, 
and  dimness  of  vision.  Then  the  pulse  would  become 
thready,  and  soon  a  state  of  complete  syncope  would 
come  on.  This  would  last  for  five  or  six  minutes,  and 
would  then  be  succeeded  by  vomiting.  The  child  was  in 
apparent  good  health,  but  never  had  convulsions,  and 
came  firom  a  family  free  from  epilepsy.  The  treatment 
consisted  in  first  accustoming  the  boy  to  handle  the  scis- 
sors himself  and  to  snap  the  blades  together.  Then  for 
a  time  one  hair  was  cut  each  day,  then  a  lock,  and  so  on, 
nti]  finally  the  peculiar  impressionability  was  entirely 
overcome.— Z^  Progrh  MUiccd,  June  21,  1884. 

Some  Points  Concerning  the  Phvsio-pathologv  of 
THE  Blood-vessels. — ^According  to  Ferraro  {London 
Medical  Record)  the  blood  of  tabetic  patients  under 
BHcroscopic  examination  presents  nothing  characteristic 
to  distinguish  it  from  that  of  a  healthy  individual.  The 
spmitaneous  coagulation  takes  place  normally.  In  dia- 
betics, the  blood  may  coagulate  in  any  point  of  the  cir- 
culatory system,  and  give  rise  to  the  formation  of 
tlirombi  causing  more  or  less  obstruction,  wherever  the 
emditions  favorable  to  its  spontaneous  coa^lation  are 
{nmd.  The  blood  of  rabbits  surcharged  artificiallv  with 
^cose  coagulates,  but  more  slowly.  When  the  mtima 
flfa  large  artery  (the  carotid)  of  a  dog  is  destroyed  either 
bjr  mechanical  or  chemical  means,  or  by  a  very  high 
temperature,  if  the  vasa  vasorum  be  not  injured  at  the 
ome  time,  the  blood  circulating  in  the  artery  does  not 
coagulate.  On  the  other  hand,  there  is  thrombotic  oc- 
dusion  of  the  artery  whenever  the  middle  coat  is  injured 
s  veil  as  the  intima,  and  especially  if,  besides  the 
^  na,  the  vasa  vasorum  have  been  destroyed.  This  ex- 
peimental  lesion  of  the  intuna  of  the  carotid  of  the  dog 
Bsimilar  to  that  which  diabetes  mellitns  produces  in  man, 
iiwhonithe  intima  of  the  arteries  is  often  lost  from  des- 
fUDation  of  its  cells,  endoartcritis  diabetica  desquanui- 
^  In  both  cases  the  circulating  blood  does  not 
^oagolate  in  the  arteries  despoiled  of  their  intima,  if  the 
«st  of  the  wall  of  the  vessel  be  alive  and  nouri^ed  as 
^  the  normal  state.  Endarteritis  diabetica,  desquamative 
^form,  described  by  the  author  in  the  organs  of  five 
vbedcs,  finds  support  in  these  experiments,  the  object 
J^vluch  was  to  produce  in  animals  hy  other  means  a 
^OQ  of  the  intima  of  the  arteries  similar  to  that  which 
JBbetes  produces  in  man.  The  results  obtained  agree 
•Aowing  the  influence  of  a  vessel-wall  thus  altered  on 


the  blood  circulating  in  the  vessel.  It  is  then  possible 
that  from  certain  morbid  conditions  the  epithelioid  lining 
of  an  artery  or  the  whole  intima  may  be  lost,  and  yet  for 
the  blood  traversing  this  vessel  not  to  coagulate  and  not 
to  form  a  thrombus,  if  other  circumstances  favoring 
thrombosis  do  not  intervene.  This  being  possible,  since 
demonstrated  by  pathological  observation  in  diabetes 
mellitus  and  by  experiment,  it  must  be  held  that  the  in- 
fluence of  the  living  arterial  wall  on  its  contained  blood, 
by  which  its  spontaneous  coagulation  is  prevented,  is  not 
due  exclusively  to  the  epithelioid  layer  investing  the  in- 
ternal surface,  but  also  to  the  rest  of  the  wall  of  the 
vessel.  If  the  epithelial  stratum  be  destroyed  by  any 
morbid  condition  whatsoever,  the  rest  of  the  wall,  if 
alive,  may  exercise  the  same  influence  on  its  contained 
blood.  In  the  normal  condition,  the  intima  of  the  arteries 
receives  the  nutritive  plasma  partly  from  the  blood  cir- 
culating in  the  interior  of  the  vessel,  by  which  it  is  con- 
stantly bathed,  and  partly  from  that  circulating  in  the 
vasa  vasorum  of  the  contiguous  middle  coat.  If  the  vasa 
vasorum  be  destroyed,  the  neighboring  intima  is  not  al- 
ways able  to  retain  its  vitality. 

Cure  of  Hydrarthrosis  by  ELECTRicrrY. — ^A  patient 
was  admitted  to  the  service  of  Dr.  Castano,  of  Buenos 
Ayres,  suflering  from  hydrarthrosis  of  the  knee.  After  a 
varied  treatment  by  flying  blisters,  cauterization,  com- 
pression, etc.,  had  been  tried  without  success,  it  was  de- 
termined to  employ  the  constant  current  from  a  battery 
of  thirty-six  elements.  The  result  was  most  gratifying. 
By  the  fourth  day  the  circumference  of  the  articulation 
had  been  reduced  some  four-fifths  of  an  inch ;  on  the 
seventh  day  no  fluctuation  could  be  perceived,  and  on 
the  ninth  day  the  joint  measured  exactly  the  same  as  its 
fellow.  Walking  was  difficult  at  first,  but  was  much  fa- 
cilitated by  the  application  of  an  elastic  bandage. — Revue 
Midicale^  June  7,  1884. 

The  Formation  of  Urea. — MM.  Gr^hant  and  Quin- 
quand  have  been  conducting  some  further  investigations 
as  to  the  places  of  formation  of  urea  in  the  economy. 
They  have  estimated  several  times  the  amount  of  urea  in 
the  blood  going  to,  and  in  that  coming  fi-om,  the  spleen 
and  liver.  The  blood  from  the  hepatic,  portal,  and 
splenic  veins  always  contained  more  urea  than  arterial 
blood  taken  firom  the  carotid  arteries.  From  this  they 
conclude  that  the  abdominal  viscera  form  urea.  It  is 
also  asserted  that  the  proportion  of  urea  is  practically 
the  same  in  arterial  and  venous  blood  from  the  limbs  and 
head.  Lymph  and  chyle  collected  from  the  thoracic  duct 
after  section  of  the  medulla  oblongata  and  the  employ- 
ment of  artificial  respiration  have  always  been  found  to 
be  richer  in  urea  than  venous  or  arterial  blood. — The 
Lancet,  June  14,  1884. 

The  Death-rate  of  Phthisis. — In  a  work  recently 
published  by  Dr.  Wiirzburg  on  "The  Influence  of  Age 
and  Sex  on  the  Mortality  Due  to  Tubercular  Phthisis," 
some  of  the  generally  accepted  notions  on  this  subject 
are  overthrown.  The  opinion  seems  to  have  been  com- 
monly entertained  that  the  greatest  number  of  deaths 
firom  consumption  occurred  at  about  the  twentieth  year. 
But  the  statistics  collected  by  Dr.  Wiirzburg  prove  that, 
after  a  large  percentage  of  infancy,  the  minimum  death- 
rate  is  met  with  from  three  to  fifteen  years,  and  that  then 
the  rise  is  a  gradual  and  steady  one  up  to  the  period  be- 
tween sixty  and  seventy  years.  After  that  age  a  rapid 
decline  is  noted.  These  statistics  are  for  Prussia,  and 
embrace  a  period  of  five  years  from  1875  ^^  i^79«  T^© 
same  condition  has  been  noted  in  Sweden  and  the  United 
States,  with  this  difference,  that  in  these  countries  there 
is  no  decline  after  the  age  of  seventy  years.  In  England, 
however,  the  highest  death-rate  falls  between  twenty  and 
thirty  years,  and  the  lowest  between  fifty  and  seventy 
years.  There  is  but  a  very  slight  difference  in  the  per- 
centage of  deaths  from  tubercular  phthisis  between  the 
city  and  the  country. — MediccU  and  Surgical  Reporter 
June  14,  1884. 


JO 


THE  MEDICAL  RECORD. 


[July  19,  1884- 


The  Medical  Record 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor- 


Published  BY 
WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 

New  York,  July  19,  Z8S4. 

PERVERTED  SEXUAL  INSTINCT. 

Sir  Thomas  Brown  once  wrote,  platonically,  that  the 
act  of  procreation  was  ''  the  fooiishest  act  a  wise  man 
commits  in  all  his  life.  Nor  is  there  anything  that  will 
more  deject  his  cooled  imagination.*'  The  physician 
learns,  however,  that  man,  so  far  from  tending  toward 
this  ideal,  is  more  apt  to  show  instincts  of  a  violently 
opposite  character,  and  finds,  far  down  beneath  the  sur- 
face of  ordinary  social  life,  currents  of  human  passion 
and  action  that  would  shock  and  sicken  the  mind  not 
accustomed  to  think  everything  pertaining  to  living  crea- 
tures worthy  of  study.  Science  has  indeed  discovered 
that,  amid  the  lowest  forms  of  bestiality  and  sensuous- 
ness  exhibited  by  debased  men,  there  are  phenomena 
which  are  truly  pathological  and  which  deserve  the  con- 
siderate attention  and  help  of  the  physician. 

Some  twenty  years  ago,  a  lawyer  of  Hanover  wrote  an 
article  describing  a  form  of  sexual  perversion  to  which 
he  was  himself  subject,  and  defending  the  acts  to  which 
his  morbid  instincts  prompted  him. 

In  1869  Westphal  reported  two  similar  cases,  and  de- 
scribed the  condition  as  a  congenital  sexual  perversion 
(contrSire  sexualempfindung) .  Subsequently  several  other 
such  histories  were  published,  and  in  1877,  Krafft-Ebing, 
in  reporting  an  additional  case,  gave  a  careful  analysis 
of  the  condition,  classifying  it  among  the  psycho-degen- 
erative states.  Drs.  J.  C.  Shaw  and  G.  N.  Ferris,  in  the 
Journal  of  Nervous  and  Menial  Diseases  for  April,  1883, 
presented  a  collection  of  previously  reported  histories, 
omitting,  however,  one  which  was  piiblished  in  The  Med- 
ical Record.  These  gentlemen  also  related  a  case  of 
their  own.  Up  to  that  time  only  twenty-one  cases  were 
on  record,  three  being  reported  by  Americans,  the  rest 
mainly  by  Germans,  and  none  at  all  by  English  ob- 
servers. 

In  a  recent  number  of  the  Irrenfreund  {yo\.  xxvi.,  No. 
I,  1884),  Krafft-Ebing  has  reported  six  more  cases. 
One  of  these  was  that  of  a  merchant,  now  living  in 
America,  who  wrote  to  Krafft-Ebing  a  letter  which  can 
but  strike  the  attention.  The  patient  says :  "  I  have 
read  your  article  in  the  TUitschrift  fur  Psychiatrie. 
Through  it  I  am,  in  common  with  thousands  of  others, 
rehabilitated  in  the  eyes  of  every  thinking  and  generous 
man,  and  I  offer  you  for  it  my  warmest  thanks.  You 
very  well  know  how  those  in  our  condition  are  despised 
and  execrated.  Though  science  at  this  late  time  has 
undertaken  to  investigate  it,  it  still  remains  the  object  of 


detestation.  I  think  that  Ulricbs  [the  Hanoverian  lawyer 
referred  to]  underestimates  the  number  of  its  victims. 
In  my  native  city  (of  13,000  inhabitants)  I  knew  per- 
sonally  twelve  '  Umings.'  In  a  city  of  60,000  inhabitants 
I  know  at  least  eighty."  The  writer  then  goes  on  to  re- 
late his  own  history. 

The  victims  of  this  perverted  instinct  have  been  termed 
by  Ulrichs  and  others  "  Umings."  If  their  number  is  as 
great  as  Krafft-Ebing's  correspondent  indicates,  it  is  cer» 
tainly  a  matter  of  importance.  It  is  not  improbable^ 
however,  that  some  of  these  are  rather  examples  of  vie* 
ious  lust  than  of  pathological  perversions. 

These  so-called  *'  Urnings  "  are  persons  whose  sexual 
feelings  can  only  be  aroused  by  intimacy  with  their  own 
sex ;  they  have  an  irrepressible  desire  to  act  the  part 
of  the  opposite  sex.  If  men,  as  is  generally  the  case, 
they  try  to  dress,  or  walk  like,  and  imitate  the  habits  of 
women.  The  very  act  of  dressing  in  women's  clothes 
excites  the  sexual  sense.  They  have  a  repugnance  to 
normal  sexual  intercourse,  and  have  no  desire  for  it 
They  attach  themselves  to  some  other  man,  and  form 
sometimes  purely  platonic  friendships  ¥rith  him.  More 
generally  they  find  some  fellow  **  Uming"  with  whom  the 
sexual  passion  is  easily  excited  by  mutual  masturbation 
or  intercourse  per  anum.  They  sometimes  form  attach- 
ments for  boys  *  or  old  men.  They  often  masturbate 
while  having  lascivious  images  of  the  male  beloved  before 
their  imagination. 

In  the  reported  cases  of  congenital  perversion,  the  ab- 
normal instinct  begins  oftenest  as  early  as  the  eighth  or 
ninth  year,  but  shows  itself  at  first,  perhaps,  only  in  an 
inclination  to  adopt  the  manners  and  practices  of  girls  or 
women.  The  victims  show  the  somatic  basis  of  their 
trouble  in  various  ways.  There  is  often  an  hereditary 
psychopathic  or  neuropathic  taint.  Epilepsy  is  some- 
times present.  There  are  noticed  in  some  cases,  though 
not  often,  defects  of  the  genital  organs,  such  as  hypo- 
spadias or  epispadias,  small  or  defective  testicles.  The 
hair  on  the  face  is  sometimes  thin,  the  voice  almost  al- 
ways soft.  The  "Urnings"  have  a  mincing  gait,  and 
sometimes  the  hips  are  broad  like  those  of  women.  Ex- 
acerbations of  the  perverted  feeling  appear  periodically* 
It  may  be  accompanied  with  melancholia  and  end  in  in- 
sanity or  suicide. 

The  mental  peculiarities  of  these  unfortunates  have 
much  in  common.  They  are  of  the  artistic,  poetical^ 
and  imaginative  temperament,  often  exhibiting  a  ten- 
dency to  rather  weak  philosophizing.  Sometimes  they 
are  of  a  vigorous  understanding.  In  most  cases  there  is 
great  mental  distress  felt  through  a  consciousness  of  their 
unnatural  instincts.  Two  or  three  have,  like  Ulrichs, 
boldly  defended  their  practices. 

Medical  jurists  have  devised  a  number  of  technical 
terms  to  cover  the  practices  that  follow  from  these  sexual 
aberrations,  which,  it  should  be  borne  in  mind,  are  still 
classed  in  all  cases  as  crimes.  The  intercourse  between 
woman  and  woman  (Lesbian  love)  is  known  as  tribadism. 
That  between  man  and  man,  or  unnatural  intercourse  be- 
tween man  and  woman,  is  known  as  sodomy.  When  the 
victim  is  a  boy  it  is  known  as  paederasty. 

If  congenital  perverted  sexual  instinct  is  a  pathologi- 

>  *'Thou  shall  not  corrupt  boys."  is  one  of  die  commandmcnu  in  die  Teadiings- 
of  the  Twelve  Apostles. 


July  19,  1884.] 


THE  MEDICAL  RECORD. 


7J 


cal  rather  than   a  vicious  condition,  the  query  arises 
whether  there  is  any  r^nedy  for  it    The  history  of  cases 
reported  shojnrs  that  sometimes  the  instinct  is  cultivated 
and  intensified  by  bad  surroundings  in  childhood,  such  as, 
for  example,  the  exclusive  society  of  women  and  im- 
moral nurses^    Excessive  sexual  indulgence  seems  to  in- 
crease it,  and  we  may  question  whether  in  a  few  cases 
the  condition  would  have  ever  developed,: were  it  not  for 
an  early  abuse  and  misdirection  of  the  sexual  powers. 
In  conditions  of  nervous  exhaustion  and  weakness,  the 
symptoms  are  exaggerated,  and  Krafit-Ebing,  in  his  last 
communication,  reports  the  case  of  a  married  man,  pre- 
vkmsly  healthy,  who  experienced  an  entire  change  in  the 
sexual  feeling,  which  lasted  for  twenty-five  years.     He 
was  then  cured  by  general  faradization  and  other  tonic 


In  conclusion,  we  believe  it  to  be  demonstrated  that 
conditions  once  considered  criminal  are  really  patho- 
logical, and  come  within  the  province  of  the  physician. 
We  have  undertaken,  therefore,  the  disagreeable  task 
of  laying  some  of  the  facts  regarding  sexual  perver- 
sion before  our  readers.  The  profession  can  be  trusted 
to  sift  the  degrading  and  vicious  from  what  is  truly 
moriMd. 

Wc  cannot  do  better  than  append  the  conclusions 
which  Krafft-Ebing  has  reached  upon  this  subject     He 
says :  •^  i.  There  exists  a  congenital  absence  of  sexual 
feeling  toward  the  opposite  sex,  at  times  even  disgust  of 
sexnal  intercourse.     2.    This  defect  occurs  in  a  phy- 
sically differentiated  sexual  type  and  with  a   normal 
development  of  the  sexual  organs.     3.  Absence  of  the 
psychical  qualities  corresponding  to  the  anatomical  sex- 
ual type,  but  the  feelings,  thoughts,  and  actions  of  a  per- 
verted sexual  instinct     4.  Abnormally  early  appearance 
of  sexual  desire.     5.  Painful  consciousness  of  the  per- 
verted sexual  desire.     6.  Sexual  desire  toward  the  same 
sex.    7,  The  sexual  desire  remains  purely  platonic  or 
finds  gratification  in  mutual  onanism,  or  in  feeling  of  the 
,  object  of  the  affections.     Often  there  is  self-pollution, 
but  for  die  want  of  something  better.     8.  There  are  symp- 
toms  of  a  morbid  excitability  of  the  sexual  desires,  to- 
gether with  an  irritable  weakness  of  the  nervous  symp- 
toms, so  that  sensuous  feelings,  magnetic  sensations,  and 
even  pollutions  occur  in  simply  touching  the  object  of 
the  affections.     9.  The  perverse  sexual  impulse  is  ab- 
nonnaUy  intense  and  rules  all  thought  and  sensation. 
The  love  of  such  individuals  is  excessive  even  to  ado- 
ration, and  is  often  followed  by  sorrow,  melancholy,  and 
jwlonsy.     10.  People  afflicted  with  this  abnormity  fre- 
qaendy  possess  an  instinctive  power  to  recognize  one 
another." 

In  diis  last  conclusion  we  cannot  agree.     The  power 
of  mutual  recognition  ii  not  instinctive  but  acquired. 


GERMAN  MEDICAL  JOURNALS. 

Thi  German-speaking  race  is  abundantly  supplied 
vith  medical  journals  of  every  conceivable  kind,  and 
they  reflect  very  well  the  character  of  the  German  medi- 
al mind.  The  number  of  special  journals  is  particularly 
peat  There  are  quarterlies,  and  monthlies,  and  even 
weeklies  devoted  to  gynecology,  neurology,  psychiatry, 
etc. 


The  leading  journals  are  the  large  weeklies :  the  Btr* 
liner  Klinische  Wochmsckrift^  the  Deutsche  Medkinische 
Wochenschrifiy  the  Wiener  Medizinische  Wochensckrifty 
etc.    These  are  not  framed  upon  the  English  or  Ameri- 
can plan.    They  rarely  contain  any  formal  editorials, 
and  but  veiy  brief  notes  of  current  events.     They  are 
filled  veith  ^eavy  original  articles,  most  of  which  are  so 
laboriously  scientific  and  minutely  technical  that  they 
would  appear  to  the  American  mind  extremely  dull. 
Interspersed  vwth  these,  however,  there  are  not  rarely 
the  rich  original  contributions  to  medical  science  which 
makes  Germany  so  famous.    A  characteristic  of  German 
periodical  literature  is  that  it  is  almost  all  written  by  the 
Professors  or  their  assistants,  or  by  some  of  the  various 
instructors  at  the  universities.     One  hears  almost  noth* 
ing  from  the  general  practitioner  who  is  so  prominent  a 
person  in  American  journalism*    There  has  of  late,  to 
be  sure,  been  something  of  a  revolt  started.     Dr.  Julius  • 
Grosser,  a  practising  physician  at  Prenzlau,  has  dared 
to  start  a  weekly  journal  in  the  interest  of  his  confreres, 
and  despite  the  frowns  of  the  great  men  of  the  universi- 
ties.   His  journal,  the  Deutsche  Medizinal-Zeitung  gives  a 
practical  summary  of  progress  in  all  departments  of  med- 
icine, and  must  prove  extremely  useful^     A  few  other 
journals  of  a  somewhat  similar  character  exist,  one,  the 
CentraUZeitung,  being  published,  like  some  of  the  French 
journals,  three  tunes  a  week.     A  further  evidence  of  the 
effort  which  is  of  late  being  made  by  German  journalists 
to  supply  the  practical  needs  of  the  physician  is  the 
growth  of  therapeutical  literature.     There  has  recently 
been  established  an  excellent  journal  devoted  to  thera- 
peutics alone,  and  a  popular  and  often-quoted  month- 
ly journal,  called  Memorabilien,  edited  by  Dr.  Betz,  de- 
votes itself  chieffy  to  therapeutics.     The  Zeitschrift  fUr 
Therapie  is  almost  everything  but  therapeutical. 

The  various  Archives^  in  which  are  contained  the  re- 
sults of  laborious  researches  in  physiology,  pathology, 
pharmacology,  and  clinical  medicine,  embody  a  mass  of 
literature  to  which  there  is  no  parallel  in  other  coun- 
tries. 

A  very  large  part  of  German  periodical  literature  con- 
sists of  minute,  carefully  recorded  observations,  patho- 
logical,  physiological,   and  clinical.    These   cover  not 
only  things  which  are  practical  but  also  everything  hav- 
ing a  bearing  on  medicine.     This  habit  of  careful  obser- 
vation and  detailed  statement  makes  an  article  very  te- 
dious ;  but  it  is  the  method  which  ensures  progress  in  a 
science  like  that  of  medicine.     In  order  to  furnish  the 
essentials  of  all  these  elaborately  recorded  studies,  and 
to  allow  a  person  with  moderate  leisure  to  follow  the 
progress  in  the  various  departments,  journals  devoted 
simply  to  abstracting  and  condensing  are  published,  and 
have  now  become  quite  numerous.     There  are  the  va- 
rious monthly  and  yearly  Jcthrbucher  and  Jahresberichtey 
besides  three  or  four  weeklies,  which  aie  entirely  devoted 
to  this  kind  of  work.     Indeed,  the  summaries  of  medical 
progress  are  nowhere  done  with  so  much  painstaking 
conscientiousness  as  by  our  German  confreres.     They 
err  only  in  sometimes  analyzing  with  too  much  care  arti- 
cles which  are  worthless.     In  this  kind  of  work,  the  Ger- 
mans can  teach  the  profession  of  other  nationalities.     In 
the  technical  part  of  journalism,  or  journalism  proper, 
they  arc  far  behind  England  and  America.     The  jour- 


72 


THE   MEDICAL  RECORD. 


(July  19,  1884. 


nals  do  not  voice  the  opinions  of  the  profession  at  large ; 
they  have  no  strong  writers,  and  when  the  weekly  notes 
are  lengthened  out  into  the  dignity  of  editorial  it  is  gen- 
erally to  express  some  comment  on  local  and  personal 
matters. 


A  CRITICISM  UPON  THE  VALUE  OF  SULPHATE  OF 
CINCHONIDIA  (CINCHONIDINE). 

It  is  known  that  the  sulphate  of  cinchonidia  is  very 
much  used  as  a  cheap  substitute,  and  probably  as  an 
adulterant,  of  quinine.  A  recent  contribution  to  the 
pharmacology  and  therapeutics  of  this  drug,  by  Professor 
J.  Marty,  of  Rennes  {Bulletin  Gin^ral  de  Th/rapeutique, 
May  30,  1884),  is,  therefore,  of  much  interest.  Having 
given  it  to  healthy  persons,  and  in  various  types  of 
malarial  fever,  he  comes  to  the  conclusion  that  cincho- 
nidia has  two  serious  defects :  i.  Its  extreme  variability 
of  action  in  healthy  and  sick  men.  2.  The  ease  with 
which  it  may  provoke  toxic  manifestations  in  doses  neces- 
sary to  produce  its  therapeutic  results. 

Professor  Marty  thinks  that  it  should  be  given  in  doses 
double  those  of  quinine,  and  that  it  is  then  an  efficient 
agent  in  the  benign  types  of  malarial  fever.  For  the 
pernicious  types  it  should  not  be  trusted.  It  does  not 
act  well  in  the  various  forms  of  malarial  headache  and 
neuralgia. 

We  believe  that  Professor  Marty's  conclusions  will  be 
found  to  harmonize  in  the  main  with  the  practical  ex- 
perience of  those  who  have  used  it  in  this  country. 
Cinchonidia  is  a  very  useful  substitute  for  quinine  in  the 
milder  affections  in  which  that  drug  is  indicated,  but 
it  is  liable  to  disappoint  the  physician  in  some  cases. 


RECTAL  ANAESTHESIA. 

M.  A.  PoNCET  publishes  in  the  Lyons  M^diccUe  an  in- 
teresting contribution  to  the  subject  of  rectal  anaesthesia. 
It  appears  that  M.  Roux,  in  1847,  first  thought  of  and 
suggested  the  plan  of  giving  ether  by  the  rectum  {Compt 
rendu  de  VAcademie  des  Sciences^  February  i,  1847,  p. 
146).  He  did  not,  however,  try  it  himself.  Three 
months  later  Dr.  Vincente-y-Hedo  published  the  results 
of  his  experiments  in  injecting  liquid  ether  into  the  rec- 
tum of  rabbits  {Gazette  mklicale  de  Farts,  1847,  ?•  317). 
Naturally,  these  experiments  led  to  no  practical  results. 
A  little  later  M.  Marc  Dupuy  injected  ether  and  water 
into  the  rectum  of  animals  and  produced  insensibility, 
but  with  so  much  injury  to  the  mucous  membrane  that 
the  experiments  were  not  repeated  on  man.  In  the 
same  year,  1847,  Pirogoff,  of  St  Petersburg,  first  pro- 
duced  anaesthesia  in  man  by  the  introduction  of  ethereal 
vapor  into  the  itctam  (Recherches  pratiques  et physiolo- 
giguessur  P etherization^  Saint-Pctersbourg,  1847).  He 
employed  the  new  procedure  in  a  number  of  cases,  rec- 
ognized its  advantages,  and  urged  its  adoption.  Dif- 
ferent apparatuses  were  constructed,  and  the  use  of 
ethereal  vapor  per  anum  was  adopted  by  Simonin  at 
Nancy,  for  a  year  or  two  subsequently. 

After  this,  it  seems  that  the  subject  was  dropped 
-entirely  for  over  thirty  years.  According  to  M.  Poncet, 
there  is  no'record  of  the  employment  of  rectal  anaesthesia 
until  M.  MoUi^re  reported  his  cases  last  spring.  Since 
that  time,  aside  firom  ten  trials  made  in  this  country, 


rectal  anaesthesia  has  been  made  the  subject  of  a  com- 
munication to  the  Soci6td  de  Biologie  by  M.  Bebierre 
{Journal  de  Midecine  de  Paris y  April  19,  1884).  M. 
Delore  has  published  an  article  upon  the  same  subject 
{Gazette  des  Hopitaux^  March  20,  1884),  and  M.  Dubois 
has  recommended  the  use  of  chloroform  vapor  per  rectum 
instead  of  ether. 

M.  Poncet  now  comes  forward  with  the  record  of  five 
cases  in  which  he  has  himself  employed  rectal  anaesthesia 
with  ether  vapor ;  and  he  sounds  a  note  of  warning  s^ainst 
this  new  procedure.  In  four  of  his  cases,  success  was 
tolerably  good,  but  in  the  fifth,  that  of  a  woman  thirty, 
seven  years  of  age,  severe  collapse  took  place  after 
insensibility  had  been  produced,  and  it  was  with  the 
greatest  difficulty  that  the  patient  was  restored. 

M.  Poncet  is  most  decidedly  of  the  opinion  that  the 
administration  of  ether  per  rectum  is  a  dangerous  pro- 
cedure,  and  one  not  to  be  adopted  by  careful  surgeons. 
This  is  the  view  which  is  now  held  in  New  York. 


PROFESSIONAL  "PIDGEN"  ENGLISH. 
No  ;  not  quite  that  bad  perhaps,  but  some  of  the  lucu- 
brations of  our  writers  are  more  remarkable  for  ambigu- 
ity than  for  scientific  value,  and  certainly  far  richer  in  bad 
grammar  than  in  sound  pathology  or  therapeutics.  We 
are  aware  that  not  every  practitioner  has  had  the  advan- 
tage of  a  collegiate  education  ;  some  apparently  never 
graced  the  benches  of  an  "  old-field  "  school.  But  there 
is  a  notable  proportion  of  college-bred  men  in  the  profes- 
sion, men  who  have  an  A.M.  or  an  LL.D.  after  their 
names,  but  who  write  vile  English,  both  as  regards  the 
wrong  use  of  words  and  the  wrong  use — or  non-use — of 
grammar. 

A  very  generally  abused  word  in  medical  literature 
is,  perhaps,  **apt."  The  persistency  with  which  writers 
use  this  word  for  "  likely  "  and  *'  liable  "  is  reaUy  marvel- 
lous.  The  following  are  a  few  examples  of  the  wrong  use  of 
words,  found  within  a  few  minutes  during  a  cursory  glance 
at  current  journals :  medical  doses  for  medicinal  doses, 
dilation  for  dilatation,  ligated  for  ligatured,  diagnosed  for 
diagnosticated,  teaspoonsful  for  teaspoonfuls,  ofi&cial  for 
officmal,  analogous  for  similar,  and  entroitus  for  introitus. 

There  is  very  common  misuse  of  "  where  "  for  "  in 
which."  Some-— almost  every — writer  speaks  of  a  "  case 
where,"  e.g.^  "  cases  are  on  record  where  post-mortem 
of  persons,"  meaning  "in  which  the  post-mortem  ex- 
amination," for  post-mortem  should  never  be  unaccom- 
panied by  the  examination.  A  writer  in  a  current  jour- 
nal says :  "  We  have  two  classes  to  treat — ^young  women 
and  married  women,''  leaving  the  reader  to  infer  that  all 
young  women  are  single  and  all  married  women  are  old. 
Another  has  manufactured  a  new  word— diuretico-muci- 
laginous.  We  have  an  idea  that  he  is  the  same  who 
says :  "  He  began  to  pass  large  quantities  of  dissolved 
stone,"  though  he  was  not  the  author  of  the   following  : 

"  Dr. ,  of y  wants  treatment  for  cross-eyes  that 

came  suddenly  on  a  girl  This  is  paralysis  of  the  recti- 
muscles  of  the  eyeball,  internal  or  external  accordingly  as 
the  squint  is  con  or  divergent"  It  has  long  been  known 
that  woman  rules  the  household,  but  a  correspondent  of 
a  St  Louis  Comic  Medical  Journal  says :  *•  Menstru- 
ation is  evidently  the  chief  governor  of  woman  and  her 


July  19'  1884-] 


THE   MEDICAL  RECORD. 


11 


^ily  relations."  This  is  important  information,  and 
should  be  strictly  kept  from  the  ears  of  "  woman's  rights  " 
women.  Another  writer  in  the  same  journal  has  with  a 
stroke  of  the  pen  cured  every  adult  dyspeptic  in  the  coun- 
try: "Dyspepsia  is  par  excellence  a  disease  of  infancy." 
We  wish  it  were  true.  But  there  is  a  dangerous  man  some- 
where whose  friends  especially  should  know  about  him. 
He  says:  "I  have  found  the  following  to  be  very  bene- 
ficial in  the  treatment  of  gonorrhoea,  which  I  would  like 
to  give  to  any  one  who  wants  it,  hoping  it  will  be  of  some 
benefit  to  the  medical  fraternity."  He  should  mend 
both  his  morals  and  his  grammar.  But  seriously,  the 
bad  English  of  the  profession  is  deplorable. 


THE  PROPOSED  S.  D.  GROSS  PROFESSORSHIP  OF 
PATHOLOGICAL  ANATOMY. 

We  have  received  a  circular  asking  us  to  assist  in  the 
effort  io  secure,  **  in  some  medical  school,*'  the  endow- 
ment of  a  memorial  professorship  to  be  designated  the 
S.  D.  Gross  Professorship  of  Pathological  Anatomy. 

We  will  cordially  support  any  movement  looking  to- 
ward the  commemoration  of  the  remarkable  work  and 
Doble  character  of  the  late  Professor  Gross.  We  but 
voice  the  sentiments  of  many,  however,  when  we  ask  if 
some  fitter  memorial  for  the  general  profession  to  con- 
tribute to  could  not  be  found  than  that  of  a  professor, 
ship  in  a  private  medical  college.  This  chair  naturally 
should  be  in  Jefferson  Medical  College,  though  it  is  not 
so  specified.  And  many,  perhaps  most,  physicians  would 
prefer  to  contribute  simply  to  the  memory  of  Gross,  not 
at  the  same  time  to  the  resources  of  a  prosperous 
medical  institution. 


A  LESSON  TO  BE  REMEMBERED. 
On  the  morning  of  Friday,  September  r,  1854,  the  chol- 
era suddenly  attacked  a  number  of  persons  residing  in 
flie  sub-district  of  Berwick,  in  the  city  of  London.  The 
outbreak  was  confined  to  the  immediate  vicinity  of  a 
veil  situated  on  Broad  Street. 

This  well  was  the  centre  of  an  infected  district :  "a 
person  starting  from  thence  and  walking  at  a  moderate 
pace  would  have  got  beyond  its  limits  in  three  minutes" 
(English  Rivers  Pollution  Reports).  During  the  month 
d  August  preceding  the  outbreak,  only  twenty-six 
cases  of  cholera  were  reported  to  the  London  authori- 
ties fi-om  this  district  (Berwick). 

The  epidemic  reached  its  height  on  September  2d,  and 
declined  about  fifty  per  cent,  on  the  5th ;  after  which  it 
dwindled  off  until  the  20th,  this  day  being  the  first  on 
which  no  death  took  place.  The  total  number  of  deaths 
in  the  district  from  the  ist  up  to  this  date  was  609. 

Investigation  showed  that  about  seventy-eight  hours 
before  the  great  outburst  of  the  disease  a  child  was  at- 
tacked with  cholera  in  the  house  No.  40  Broad  Street, 
and  its  dejections  were  emptied  into  a  drain  which  ran 
within  a  few  feet  of  the  well.  The  water  from  this  well 
was  very  popular  with  the  neighborhood. 

Analysis  showed  that  it  contained  in  100,000  parts 
137  parts  total  solids  and  7.72  parts  organic  and  vola- 
tile noatter.  It  was  clearly  shown  that  nearly  all  the 
persons  attacked  with  the  disease  had  drank  the  water 
^sm  this  well. 


In  one  case,  an  old  lady  and  her  niece,  residing  at  a 
distance,  had  been  in  the  habit  of  having  the  water 
sent  to  them  daily.  They  both  had  cholera,  while  none 
of  their  neighbors  contracted  it. 

The  history  of  this  well  should  be  engraved  on  the 
mind  of  every  sanitarian.  The  activity  displayed  by 
health  authorities  in  searching  out  and  stopping  the  water 
from  city  wells  shows  that  it  has  not  been  lost  on  them. 
The  use  of  such  water  for  the  preparation  of  aerated 
drinks  is  the  more  dangerous,  since  such  beverages  are 
prescribed  for  invalids. 

The  history  of  the  cholera  in  Manchester  and  Glasgow 
illustrates  most  forcibly  the  importance  of  a  pure  water 
supply  for  cities.  Until  1851  the  people  of  Manchester 
and  Salford  obtained  water  partly  from  wells  and  partly 
from  the  River  Irwell.  Both  these  sources  were  much 
polluted  with  excrementitious  matters. 

In  185 1  a  pure  supply  of  water  was  introduced  into 
these  towns.  The  following  figures,  taken  from  the  re- 
port of  the  Rivers  Pollution  Commission,  show  the  mor- 
tality during  the  polluted  and  pure-water  periods  : 

Total  mortality  in  Manchester  and  Salford,  polluted- 
water  period:  1832,  890;  1849,  'j^'SJ  pure-water 
period  :  1854,  50  ;  1866,  88. 

The  history  of  the  disease  in  Glasgow  affords  evidence 
equally  conclusive.  Until  1859  ^^  water  supply  was 
drawn  from  the  Clyde,  and  was  polluted  by  the  drainage 
of  towns  higher  up  the  river.  After  that  year  a  pure  supply 
was  obtained  from  Loch  Katrine. 

Total  mortality  in  Glasgow,  poUuted-water  period : 
1832,  2,842;  1849,  3»772;  1854,  3,886;  pure-water 
period  :  1866,  68.  Mortality  per  10,000  of  population, 
polluted-water  period :  1832,  140;  1849,  ^^^\  i854» 
119;  pure-water  period :  1866,  16. 

These  facts  are  not  new  to  sanitarians  who  have 
studied  the  subject,  and  they  can  be  multiplied  to  any 
extent  desirable  to  prove  the  intimate  connection  of 
cholera  with  water  supply.  We  repeat,  then,  we  are  glad 
to  see  that  the  health  authorities  in  this  city  are  so  thor- 
oughly alive  to  the  necessity  of  inspection  of  wells,  and 
are  so  strenuously  in  favor  of  preventing  the  use  of  the 
water  from  them  for  drinking  purposes. 


Cholera  and  the  Price  of  Disinfectants. — ^The 
alarm  over  cholera  has  caused  a  marked  increase  in  the 
demand  for  disinfectants  and  cholera  drugs.  A  member 
of  a  large  drug  firm  in  this  city  states  that  opium  has 
advanced  twenty-five  cents  per  pound  in  the  past  few 
days.  It  may  be  questioned  whether  the  rise  in  opium 
comes  from  the  scare  or  the  shortness  of  the  crop  this 
year.  Sulphate  of  morphine  is  twenty  cents  per  ounce 
higher  and  oil  of  peppermint  has  recently  advanced.  The 
demand  for  camphor  is  increasing,  and  a  rise  is  expected. 
Chloride  of  lime  is  being  largely  purchased,  and  is 
twenty-five  cents  per  hundred  pounds  higher.  Carbolic 
acid  crystals  have  advanced  from  twenty-five  to  thirty 
per  cent.  There  is  considerable  buying  by  France  in 
England  also. 

The  Chicago  Medical  Journal  appears  in  a  new 
and  much  improved  dress,  and  announces  as  its  editors 
Drs.  James  Nevins  Hyde,  W.  W.  Jaggard,  and  Harold 
N.  Moyer. 


74 


THE  MEDICAL  RECORD. 


Duly  19,  1884 


^enrs  at  tite  WISiziU. 


Death  from  the  Bite  of  a  Rattlesnake. — ^A  snake* 
charmer  in  this  city,  named  James  Reilly,  was  bitten  in 
the  hand  by  a  rattlesnake,  and  died  in  forty-eight  hours 
in  consequence.  Large  amounts  of  whiskey  and  am- 
monia were  given,  but  without  avail.  An  autopsy  on 
the  body  was  made  by  Dr.  W.  H.  Welch. 

The  Summer  Corps  of  Sanitahy  Inspectors  went 
to  4,504  houses  last  week,  and  visited  24,099  families, 
finding  811  sick  persons,  to  whom  they  gave  prescrip- 
tions or  medicine,  and  tickets  for  excursions.  Of  the 
patients,  365,  nearly  all  of  whom  were  children,  suffered 
from  diarrhoea,  118  had  trouble  with  the  respiratory  or- 
gans^  and  70  were  sick  of  diseases. 

Lepers  to  be  Put  on  Exhibition. — A  unique  variety 
of  the  moral  show  has  been  devised  by  a  Californian, 
calling  himself  Dr.  C.  C.  O'Donnell.  He  has  secured 
two  Chinese  lepers  with  a  large  portfolio  of  photographs 
of  other  cases,  and  he  proposes  to  travel  East  and 
exhibit  them.  The  show  is  in  the  interest  of  anti- 
Chinese  immigration.  Dr.  O'Donnell  claims  that  there 
are  between  two  hundred  and  two  hundred  and  fifty 
lepers  in  San  Francisco  already,  and  that  the  disease  is 
increasing. 

Faith-Surgery. —  The  following  is  an,  interesting 
specimen  of  advertisement  that  appeared  recently  in  a 
daily  paper  :  "  Faith  Surgery. — My  dislocated  shoulder 
and  broken  collar-bone  instantly  set  and  cured  by  Rev. 

Dr. ,  Christian  Healer  [address  is  here  given].    Was 

able  to  do  heavy  family  washing  next  day.     Mrs. • 

Doccors  and  ministers  can  interview  me.'' 

The  Congress  of  German  Naturalists  and  Phy- 
sicians will  be  held  at  Magdeburg,  September  18  to  23, 
1884.  The  medical  and  surgical  work  at  this  meeting 
promises  to  be  very  considerable.  Sections  are  organized 
for  all  the  specialties,  and  many  prominent  physicians 
have  already  furnished  the  titles  to  the  papers. 

Prizes  for  Surgical  Essays. — ^The  Medico-Surgical 
Society,  of  Bologna,  has  offered  two  prizes  of  500  lires 
each.  First  prize,  Sgarze,  for  the  best  essay  on  The 
Surgical  Treatment  of  Pulmonary  Cavities.  Second 
prize,  Gajani,  The  Surgery  of  Diseases  of  the  Stomach. 
The  essays  must  be  written  in  Italian,  French,  or  Latin. 

The  Progress  of  Cholera  in  Europe. — ^The  epi- 
demic of  cholera  continues  to  increase,  as  will  be  seen  by 
the  accompanying  figures  of  deaths :  July  9th,  Toulon,  1 1 ; 
Marseilles,  23.  July  loth,  Toulon,  11;  Marseilles,  59. 
July  nth,  Toulon,  13  ;  Marseilles,  74.  July  12th,  Toulon, 
22;  Marseilles,  65.  July  13th,  Toulon,  35;  Marseilles, 
57.  July  14th,  Toulon,  11  ;  Marseilles,  66.  July  15th, 
Toulon,  20 ;  Marseilles,  69.  Cases  of  cholera  are  said 
to  have  occurred  in  the  surrounding  country.  Two  cases 
have  been  reported  also  in  Transylvania  and  one  at 
Nimes,  France.  The  reported  occurrence  of  cases  in 
Paris  and  Lyons  is  denied.  Dr.  Koch  continues  to 
assert  that  the  disease  will  spread  throughout  Europe, 
but  thinks  that  it  may  be  kept  from  America  this  year  at 
least.  The  Paris  Acad^mie  de  M6decine  has  been  asked 
to  give  an  official  opinion  regarding  the  cholera,  its  mode 


oif  prevention,  etc.  This  the  Acadtoie  seems  disinclined 
to  do  because  the  Government  refused  to  take  its  advice 
as  to  holding  the  fUte  of  July  14th.  If  the  Acad6mie 
treats  cholera  in  the  same  discursive  manner  that  it  did 
typhoid  fever,  it  will  be  a  year  before  its  opinions  will 
be  formulated.  Nearly  all  countries  have  quarantined 
against  the  French  Mediterranean  ports.  Our  own 
Government  will  oblige  vessels  from  Europe  bound  for 
the  United  States  to  have  certified  clean  bills  of  health 
from  the  American  consuls. 

The  Number  of  Cases  of  Small-pox  in  London 
last  week  was  1,200.  Some  parts  of  the  city  are  reported 
to  be  in  a  very  filthy  condition. 

Disinfecting  Toulon. — "  Every  means  of  disinfection 
at  Toulon,"  says  The  British  Medical  Journal^  **  has  been 
adopted.     The  city  is  watered  with  a  solution  of  carbolic 
acid  and  chloride  of  lime.     Those  who  have  died  from 
cholera  are  buried  at  a  great  depth  underground.     Rail- 
way travellers  are  sprinkled  with  carbolic  acid  solution. 
The  soldiery  are  encamped  outside  the  town.     The  sick 
sailors  are  put  on  board  the  Entreprenaule  to  be  ex- 
amined;  the   cholera-patients  are  removed   to  the  St. 
Maudrier  Hospital,   which  is  reserved  for  them.    The 
crews  have  been  placed  on  vessels  at  anchor  outside  the 
port.     The  Ministers  of  War  and  the  Marine  have  given 
orders  to  the  authorities  of  arsenals  to  deliver  to  the  civil 
authorities  all  the  material  for  camping  out  that  they  may 
require.    MM.  Brouardel  and  Proust  arrived  on  Tuesday, 
June  24th,  at  Toulon,  with  a  Ministerial  decree  to  effect 
whatever  measures  they  judge  necessary  for  the  public 
safety ;  to  ordain  the  evacuation  of  entire  districts,  and  of 
the  city  itself,  if  requisite.     Dr.  Rochaud  left  Paris  for  Tou- 
lon on  Tuesday  evening,  also  MM.  Strauss  and  Rout,  in 
order  to  continue  their  scientific  researches.     They  are 
also  commissioned  to  make  a  strict  inquiry  into  the 
origin  of  the  outbreak.** 

Fifty-second  Annual  Meeting    of  the   British 
Medical  Association. — ^This  association  will  hold  its 
annual  meeting  at  Belfast,   on  July   29   to   August  i, 
1884.     President,  Dr.  A.  T.  H.  Waters,  of  Liverpool. 
President-Elect,   Dr.   James  Cuming,  of  Belfast.     The 
address  in  Medicine  will  be  delivered  by  Dr.  William  M. 
Ord,  of  London  ;  that  in  Physiology  by  Dr.  Peter  Red- 
fern,  of  Belfast ;  that  in  Obstetrics  by  Dr.  Oeorge  H, 
Kidd,  of  Dublin.     A  number  of  special  discussions  have 
been  arranged.     Among  them  we  note  one  on  Albunii* 
nuria,  introduced  by  Dr.  George  Johnson ;  one    on    the 
Plaster  Jacket,  introduced  by  Dr.  L.  H.  Sayre  ;   one  on 
Extra-Uterine    Foetation,  introduced  by  Lawson    Tait  ; 
one  on  a  New  Antipyretic,  introduced  by  Dr.  Alexander 
Collie  and  by  Dr.  Dujardin-Beaumetz.     There   will  be 
the  usual  annual  museum,  and  a  large  number  of  excur- 
sions and  entertainments  have  been  planned. 

Precautions  Against  Cholera. — ^The  members  of 
the  summer  corps  of  visiting  physicians  and  the  Fruit 
Inspectors,  recently  appointed  by  the  Health  Depart- 
ment, have  received  supplementary  instructions  in  regard 
to  their  duties  from  Dr.  E.  H.  Janes,  the  Assistant  Sani- 
tary Superintendent,  in  view  of  the  possible  advent  of 
cholera  in  this  city  and  its  vicinity.  All  cases  of  con- 
tagious  disease  discovered,    whether   the  patients    are 


July  19, 1884.] 


THE  MEDICAL  RECORD. 


75 


under  treatment  or  not,  are  to  be  immediately  reported 
to  the  health  bureau,  giving  name,  age,  and  residence  of 
the  patient.  In  view  of  the  possible  advent  of  cholera, 
special  attention  is  to  be  paid  to  shanty  neighborhoods 
in  uDsewered  portions  of  the  city,  where  excreta^  are 
deposited  in  shallow  vaults  or  upon  the  surface  of  the 
ground,  and  where  the  water  supply  is  from  springs  or 
suface  wells» 

The  Minnesota  State  Medical  Society. — ^The 
phjrsicians  of  Minnesota  need  stirring  up,  as  well  as 
those  of  Louisiana,  according  to  the  Northwestern 
Lancet.  The  last  State  meeting  was  a  success  socially, 
bat  in  scientific  and  practical  work  and  in  attendance 
it  was  a  failure. 

The  Hospital  Saturday  and  Sunday  Funds  in 
England  amount  to  about  a  million  and  a  quarter  of 
dollars  annually. 

Death  from  the  Administration  of  Bichloride  of 
Mkthylene. — Another  death  must  be  scored  against 
the  comparatively  little  used  anaesthetic,  bichloride  of 
methylene.  In  this  case  the  victim  was  the  daughter  of 
a  physician  of  Lancashire,  Enghind.  The  young  lady, 
twenty-three  years  of  age,  was  to  be  submitted  to  a 
slight  surgical  operation.  The  anaesthetic  had  been 
given  only  three  minutes,  and  scarcely  ten  minims  had 
been  inhaled,  when  the  heart  suddenly  ceased  to  beat 
Respiration  also  stopped.  All  efforts  at  resuscitation 
proved  unavailing.  A  previous  examination  had  failed 
io  show  any  signs  of  heart  or  lung  disease. 

The  True  Use  of  a  Porous  Plaster,  according  to 
a  Milwaukee  druggist,  is  ««to  retain  the  back  in  its 
proper  |place  and  let  the  pain  crawl  out  through  the 
holes." 

Is  Conviction  for  Abortion  Possible  in  Ohio  ? — 
Under  this  head  the  Columbus  Medical  JourruU  cites  a 
nnmber  of  cases  in  which  abortionists  failed  to  be  con- 
victed, and  sums  up  the  state  of  affairs  as  follows  :  ''  i.  If 
the  abortionist  does  his  work,  his  victim  alone  being 
prify  to  it,  he  is  safe  ;  for  if  she  lives,  she  will  not  inform 
against  him,  while  if  she  dies,  her  statements  are  entirely 
worthless  as  evidence.  2.  If  others  are  privy  to  the  act, 
the  prosecution  must  prove  that  the  foetus  was  actually 
Mng  at  the  time  of  the  operation ;  and  this,  at  least 
after  'quickening' — and  even  then  only  on  the  testi- 
mony of  an  expert  making  an  examination  at  the  time — 
is  of  course  impossible." 

A  Congress  of  Polish  Doctors  and  natural  philoso- 
phers took  place  at  Posen,  ending  on  June  4th.  There 
were  three  hundred  present,  some  having  come  from 
Egypt,  India,  and  other  distant  parts  for  the  purpose, 
The  next  congress  will  be  held  at  Warsaw  or  Lemberg. 

Louisiana  Doctors  Asked  to  Wake  up.— We  sin- 
cerely commend  the  efforts  of  Dr.  Richard  H.  Day, 
President  of  the  Louisiana  State  Medical  Society,  to 
aioose  the  slumbering  intellects  of  the  Louisiana  doctors 
into  greater  activity.  "  Respected  confreres,"  he  says,  in 
a  dnnilar  letter,  "  when  contrasted  with  the  esfrit  de 
corps  of  the  medical  profession  in  other  States,  and  es- 
pecially with  the  glowing  enthusiasm  of  the  late  Texas 
State  Medical  Meeting  in  Belton,  the  languor  and  in- 
ference of  the  phjrsicians  of  Louisiana  in  all  that  per- 


tains to  the  unity  and  advancement  of  the  medical  pro- 
fession must  be  profoundly  humiliating  to  all  true  lovers 
of  the  science  and  the  art  of  medicine.  Brothers  of 
the  medical  profession  wake  up!  start  into  a  new 
and  more  vigorous  life  !  Let  your  medical  and  lite- 
rary attainments  and  capacity  for  usefulness  be  no  longer 
hid  in  slothfiilness,  but  let  us  begin  at  once  and  or- 
ganize the  regular  medical  practitioners  of  the  whole 
State  into  town,  parish,  and  district  medical  societies,  and 
bring  up  to  our  next  State  meeting  an  organization  and 
a  work  and  a  live  membership  that  shall  thrill  our  very 
hearts  with  joy,  and  place  our  State  Society  upon  a  solid 
and  sure  foundation."  Louisiana  medicine  is  dead  in- 
deed if,  with  the'  incitement  of  such  an  appeal  and  a 
prospective  Exposition,  it  does  not  arouse  itself. 


THE  SIMS  MEMORIAL  FUND. 

To  the  Medical  Profession  and  Others  throughout  the 
World: 

The  great  achievements  of  Dr.  J.  Marion  Sims  call 
for  some  more  lasting  testimonial  than  obituaries  and 
eulogies.  To  him  medical  science  is  indebted  for  much 
brilliant  and  original  work,  especially  in  gynecological 
surgery.  Those  who  have  been  benefited  by  his  teach- 
ings and  new  operations,  and  such  as  have  had  the  direct 
advantage  of  his  personal  skill  are  among  the  first  to 
recognize  and  ackiiowledge  this  debt 

To  him  is  due  the  honor  of  giving  the  first  strong  im« 
pulse  to  the  study  of  gynecological  surgery  in  America. 

It  is  believed  that  the  medical  profession  everywhere, 
the  vast  number  of  women  who  owe  their  relief  from 
suffering  directly  to  him,  and  those  who  realize  the 
benefits  he  first  made  possible,  will  gladly  unite  thus  to 
honor  the  man  through  whose  originsd  and  inventive  ge* 
nius  such  blessings  have  been  conferred  upon  humanity. 

At  the  suggestion  of  many  fiiends,  therefore,  the  sub- 
joined committee  has  been  organized,  and  it  is  proposed 
that  a  suitable  monument  be  erected  to  his  memory  in 
the  city  of  New  York. 

To  this  end  the  active  co-operation  of  the  medical 
profession  and  the  many  other  friends  of  Dr.  Sims 
throughout  the  world  is  respectfiiUy  solicited.  Contribu- 
tions of  one  dollar  and  upward  may  be  forwarded  to  the 
journal  which  has  been  constituted  tlie  treasury  of  this 
fiind — The  Medical  Record,  New  York. 

FORDYCE  BARKER,  M.D.,  Chairman. 
GEORGE  F.  SHRADY,  M.D.,  Secretary. 

Thomas  Addis  Emmet,  M.D.,  New  York. 

T.  Gaillard  Thomas,  M.D.,  " 

William  T.  Lusk,  M.D.,  '* 

William  M.  Polk,  M.D.,  " 

Paul  F.  MundA,  M.D.,  " 

S.  O.  Vander  Poel,  M.D.,  « 

Frank  P.  Foster,  M.D.,  " 

E.  S.  Gaillard,  M.D.,  « 

Alex.  J.  C.  Skene,  M.D.,  Brooklyn,  N.  Y. 

Samuel  D.  Gross,  M.D.,  Philadelphia,  Pa. 

WiLLLAM  Goodell,  M.D.,  " 

James  R.  Chadwick,  M.D.,  Boston,  Mass. 

William  H.  Byford,  M.D.,  Chicago,  III 

A.  Reeves  Jackson,  M.  D.,       " 

Thad.  a.  Reamy,  M.D.,  Cincinnati,  O. 

C.  D.  Palmer,  M.D.,  « 

George  J.  Engelmann,  M.D.,  St.  Louis,  Mo. 

R.  Beverley  Cole,  M.D.,  San  Francisco,  CaL 

H.  F.  Campbell,  M.D.,  Augusta,  Ga. 

R.  B.  Maury,  M.D.,  Mempms,  Tenn. 

E.  S.  Lewis,  M.D.,  New  Orleans,  La. 

J.  T.  Searcy,  M.D.,  Tuskaloosa,  Ala. 


76 


THE  MEDICAL  RECORD. 


[July  19, 1884. 


R.  A.  KiNLOCH,  M.D.,  Charleston,  S.  C. 
Hunter  Maguire,  M.D.,  Richmond,  Va. 
S.  C.  BijSEY,  M.D.,  Washington,  D,  C. 
Harvey  L.  Byrd,  M.D.,  Baltimore,  Md. 
W.  T.  Howard,  M.D.,  " 

D.  W.  Yandell,  M.D.,  Louisville,  Ky. 
Seth  C.  Gordon,  M.D.,  Portland,  Me. 
Frank  E.  Beckwith,  M.D.,  New  Haven,  Conn. 
A.  W.  Knox,  M.D.,  Raleigh,  N.C. 

L.  W.  Oakley,  M.D.,  Elizabeth,  N.  J. 
A.  T.  Woodward,  M.D.,  Brandon,  Vt. 
Albert  H.  Crosby,  M.D.,  Concord,  N.  H. 

E.  S.  DuNSTER,  M.D.,  Ann  Arboi,  Mich. 
Alex.  J.  Stone,  St.  Paul,  Minn, 


List  of  Additional  Subscribers. 

F.  A.  McGuire,  M.D.,  New  York $1  00 

A.  H.  Fridenburg,  M.D.,      '*         2  00 

J.  G.  Wallach,  M.D.,             ''         i  00 

A.  A.  Davis,  M.D.,               "         i  00 

H.  T.  Hanks,  M.D.,              **         5  00 

Geo.  V.  Hann,  M.D.,            "         i  00 

W.  J.  Morton,  M.D.,             "         5  00 

S.  H.  Dessau,  M.D.,              **         3  00 

Cash,                                     **         1  00 

James  Mitchell,  M.D.,           "         i  00 

B.  Morje,  M.D.,                    "         i  00 

K  Flies,  M.D.,                      **         i  00 

D.  F.  King,  M.D.,                **         2  00 

E.  Hochheimer,  M.D.,          **         2  00 

A.  Friedman,  M.D.,              "         i  00 

G.  W.  Jacoby,  M.D.,             "         2  00 

A.  A.  Hill,  M.D.,  Lexington,  N.  C. . .  3  00 
Drs.  R.  L.  Payne  (Sr.  and  Jr.),  Lexington,  "  . .  3  00 
S.  B.  Evans,  M.D.,  StatesvUle,  "  . .  i  00 
Thos.  E.  Anderson,  M.D.,  "  **  . .  i  00 
L.  Harrill,  M.D.,  "  "  . .  i  00 
Mrs.  M.  D.  Miller,  "  "  . .  i  00 
Mrs.  W.  J.  Coite.  "  "  . .  i  00 
J.  S.  Knight,  M.D.,  Penny  Hill,  Pitt  Co.,  "  . .  5  00 
P.  H.  Mayo,  M.D.,  Falkland,            **          "     •  •  5  00 

F.  C.  James,  M.D.,  Bethel,  "  "  . .  i  00 
Chas.  J.  O'Hagan,  M.D.,  Greenville,  "  «*  . .  5  00 
W.  M.  B.  Brown,  M.D.,  "  "  "  . .  5  00 
Zeno  Brown,  M.D.,  ''  "  '*  . .  5  00 
Frank  W.  Brown,  M.D.,  "  "  "  . .  5  00 
Robert  J.  Gill,  M.D.,  Henderson,  **  . .  2  00 
J.  H.  Tucker,  M.D.,  "  "  . .  3  00 
T.  S.  Royster,  M.D.,  Williamsborg,  "  . .  2  00 
W.  H.  Lilly,  M.D.,  Concord,                        "     ..  i  00 

C.  G.  Smith,  M.D.,  Mill  Hill,  **  . .  i  00 
J.  W.  Vick,  M.D.,  Selma,                               "     . .  i  00 

B.  W.  Robinson,  M.D.,  Fayetteville,  "  . .  5  00 
Thos.  F.  Wood,  M.D.,  Wilmington,  '*  . .  5  00 
Geo.  A.  Foote,  M.D.,  Warrenton,  "  . .  2  00 
W.  O.  McDowell,  M.D.,. Scotland  Neck,  "  . .  i  00 
Geo.  W.  Long,  M.D.,  Graham,  **  . .  i  00 
Mrs.  J.  W.White,  '*  "  . .  2  00 
Eugene  Grissora,  M.D.,  Raleigh,  "  ..  5  00 
W.  J.  Royster,  M.D.,  "  "  . .  5  00 
R,  H.  Lewis,  M.D.,              "                         «*     . .  10  00 

E.  B.  Haywood,  M.D.,  "  "  . .  5  00 
A.  W.  Knox,  M.D.,  *  '•  . .  8  50 
P.  E.  Hines,  M.D.,               "                          "     . .  2  00 

F.  T.  Fuller,  M.D.,  "  "  . .  i  00 
James  McK.ee,  M.D.,  **  "  . .  i  00 
Sion  H.  Rogers,  M.D.,         "                          *«     . .  i  00 

Clinton  Wagner,  M.D.,  New  York 50  00 

J.  C.  Acheson,  M.D.,             **         3  00 

P.  J.  Lynch,  M.D. ,                "         200 

Little  Rock  and  Pulaski   Co.   Medical  Society, 

Little  Rock,  Ark 25  00 

Alumni  Association  of  the  Faculty  of  Physic,  Uni- 
versity of  Maryland,  Baltimore,  Md 25  00 


From  a  I^ady  in  Baltimore,  Md $3  00 

Gasper  Griswold,  M.D.,  New  York c  00 

M.  H.  Henry,  M.D.,                «         500 

L.  Waldstein,  M.D.,               "         2  00 

W.  T.  Alexander,  M.D.,         **         5  00 

J.  B.  White,  M.D.,     .             **         500 

H.  W.  Mitchell,  M.D.,            "         5  00 

W.  R.  Birdsall,  M.D.,              '*         500 

Louis  Elsberg,  M.D.,              "         5  00 

E.  H.  M.  Sell,  M.D.,              "         5  00 

Robt.  A.  Murray,  M.D.,         **         5  00 

S.  B.  W.  McLeod,  M.D.,         "         5  00 

E.  R.  Chadbourne,  M.D.,        "         2  00 

Cash,                                       "         10  00 

J.  P.  Munn,  M.D.,                  "         5  00 

W.  Thurman,  M.D.,                 "         10  00 

Charles  C.  Lee,  M.D.,             "         50  00 

Mrs.  D.  L.  Yulee,  M.D.,  Washington,  D.  C 10  00 

J.  F.  Hartigan,  M.D.,               "              "      5  00 

Albert  Smith,  M.D.,           Philadelphia,  Pa 100  00 

Theophilus  Parvin,  M.D.,             "            " 100  00 

EUwood  Wilson,  M.D.,                "            ** 50  00 

Wm.  H.  Parrish,  M.D.,               "            " 25  00 

D.  Hayes  Agnew,  M.D.,             "             " 50  00 

J.  M.  Da  Costa,  M.D.,               "            " 50  00 

Wm.  Pepper,  M.D ,                     "            " 50  00 

J.  Ewing  Mears,  M.D.,                "            *' 25  00 

Wm.  H.  Pancoast,  M.D.,             "            *• 50  00 

W.  H.  Warder,  M.D.,                  "            '* 50  00 

John  Brinton,  M.D.,                     **             " 25  00 

Addinell  Hewson,  M.D.,             '*            " 25  00 

R.  M.  Girvin,  M.D.,                    **            " 25  00 

W.  V.  Keating,  M.D.,                  "             " 10  00 

J.  M.  Keating,  M.D.,                  **             " 10  00 

W.  M.  Welch,  M.D.,                   *<             ** 10  00 

Henry  Beates,  M.D.,                   *'             " 10  00 

C.  H.  Thomas,  M.D.,                  *<             " 5  00 

D.  F.  Willard,  M.D.,                   "            ** 10  00 

Wm.  Thompson,  M.D.,               «»             " 10  00 

M.  Franklin,  M.D.,                      ««             ** 10  00 

Samuel  Lewis,  M.D.,                   "             ** 10  00 

R.  J.  Dunglison,  M.D.,               "             " 10  00 

M.  B.  Musser,  M.D.,                  "             " 5  00 

S.  S.  Stryker,  M.D.,                    "            ** 5  00 

K.  Y.  Evans,  M.D.,                    "            " 5  00 

Wharton  Sinkler,  M.D.,               "            " 10  00 

Wm.  Hannah,  M.D.,  Wilson  County,  Tenn i  00 

W.  W.  Prater,  M.D.,             "                   **    i  00 

J.  L.  Fite,  M.D.,  Lebanon,                      **     i  00 

Geo.  Rustedt,  M.D.,  Shrewsbury,  Vt i  00 

E.  N.  S.  Morgan,  M.D.,  Bennington,  Vt i  00 

R.  W.  Bennett,  M.D.,              «            " i  00 

E.  O.  Rogers,  M.D.,                 "            " i   00 

J.  H.  Putnam,  M.D.,  Rutland,              " i  00 

D.  K.  Crane,  M.D.,           '*                   " i   00 

Walter  Carpenter,  M.D.,  Burlington,     " i   00 

L.  M.  Bingham,  M.D.,              "             •* i   00 

A.  P.  Grinnell,  M.D.,                "             ** i   00 

Geo.  C.  Briggs,  M.D.,               "            " i  00 

Jno.  B.  Wheeler,  M.D.,            *«            "   i    00 

L.  Woods,  M.D.,   Pittsford,                   " i   00 

H.  H.  Swift,  M.D.         "                        " X   00 

C.  A.  Flanders,  M.D.,  **                        <* i    00 

Chas.  W.  Peck,  M.D.,  Brandon,           " 1   00 

J.  J.  Tobias,  M.D.,             '*                   " i   00 

O.  G.  Dyer,  M.D.,              "                   " i   00 

Chas.  S.  Boynton,  M.D.,    "                   " i    00 

A.  T.  Woodward,  M.D.,     **                   " 5   00 

Wm.  P.  Wright,  M.D.,  Whiting,             " i    00 

T.  E.  Wakefield,  M.D.  Fair  Haven,      " i    00 

E.  D.  Ellis,  M.D.,                *'                  " I    00 

R.  Lape,  M.D.,                    **                  « i    00 

Charles  D.  Smith,  M.D.,  New  York 10  00 

Charles  A.  Leale,  M.D.,          "        10  00 

H.  Skelton  Carter,  M.D.,         "         5   00 

S.  Waterman,  M.D.,                "         5   00 


July  19,  1884.] 


THE  MEDICAL  RECORD. 


n 


iljejjrorrts  0f  J^ocietieB. 


THE  ACADEMY  OF  MEDICINE  OF  PARIS. 
Stated  Meetings  June  1 7,  1884. 
M.  A.  GuiRiN,  President,  in  the  Chair. 

(Special  Report  ftnr  Ttas  Mksical  RsoMtDb) 

AfTSR  the  members  had  been  called  to  order,  the  Presi- 
dent aonounced  that  at  its  next  meeting  the  Academy 
would  resolve  itself  into  the  committee  of  the  whole  to 
hear  the  report  upon  the  applications  for  corresponding 
membership. 
M.  Cusco  then  exhibited  a  new  form  of 

urethral  sound, 

made  according  to  his  directions  by  M.  Collin.  It  was 
partly  rigid  and  partly  elastic,  and  so  constructed  as  to 
follow  with  ease  the  curves  of  the  urethra. 

M.  Legouest  stated  that  since  the  last  meeting  of  the 
Academy  he  had  read  an  article  in  the  Lyon  Medical^  by 
MM.  Deperet  and  Boisset,  on 

THE  microbe  of  THE  BISKRA  BUTTON. 

These  gentlemen  had  also  cultivated  the  microbe,  and 
had  injected  it  into  a  number  of  animals  of  different  spe- 
cies, and  had  obtained  results  corresponding  exactly  with 
those  recorded  by  M.  Duclaux.  In  one  case  a  slut, 
brought  from  Biskra,  had  the  specific  boil  on  its  leg. 
This  animal  subsequently  gave  birth  to  two  puppies  who 
also  had  the  Biskra  buttons.  Notwithstanding  this  addi- 
tjonal  testimony,  M.  Legouest  was  still  somewhat  skep- 
tical as  to  the  specific  nature  of  the  microbe  found  in 
these  cases  of  Aleppo  evil 

M.  Marc  S6e  desired  to  call  the  attention  of  the  mem- 
bers to  the  excellent  results  obtained  by 

COMPRESSION    in  THE   TREATMENT  OF   HYDRARTHROSIS. 

He  thought  it  superior  to  the  method  advanced  by  M. 
Labb^  at  the  previous  meeting.  He  made  compression 
by  Dieans  of  an  ordinary  Esmarch's  bandage.  He  prom> 
isedtogive  a  more  extended  description  of  the  procedure 
at  some  future  meeting. 
M.  A.  Gautier  then  read  a  note  upon  the 

SYNTHESIS   OF   XANTHINE, 

which  he  had  succeeded  in  accomplishing.     This  was,  he 
claimed,  the  first  step  made  in  the  synthesis  of  albuminoid 
bodies.    Xanthine  differs  from  uric  acid  only  in  contain- 
ing one  atom  less  of  oxygen. 
K.  CouN,  of  Alfort,  then  read  a  paper  upon 

SEPTICiEMIA, 

in  which  he  came  to  the  defence  of  the  micro-organisms, 
daiming  that  it  was  by  no  means  proven  that  the  part 
plajed  by  them  in  the  production  of  disease  was  so  great 
as  it  was  now  the  fashion  to  believe.  He  maintained 
that  the  experiments  of  M.  Duclaux,  described  at  the 
last  meeting,  were  improperly  conducted.  The  microbe, 
be  said,  is  endowed  with  such  a  marvellous  power  of  re- 
production that  it  would  be  sufficient  for  the  purposes  of 
the  experiment  to  inject  a  fraction  of  a  drop,  instead  of 
twenty  drops,  as  had  been  done. 

Septicaemia,  he  continued,  is  on^  of  those  as  yet  im- 
perfectly undlerstood  conditions  in  which  the  changes 
occurring  may  be  due  to  one  or  several  of  a  number  of 
Guises — ^microscopic  organisms,  septic  agents,  ptomaines, 
etc  Among  certain  animals,  such  as  rabbits  and  birds, 
septicaemia  could  be  very  readily  produced,  while  others, 
^  dogs,  oxen,  and  sheep,  were  hardly  at  all  susceptible 
to  the  disease.     The  affection  known  as 


GANGRENOUS    SEPTICEMIA 

is  not  certainly  specific  in  its  nature.  It  cannot  be  dis- 
^nished,  in  animals  at  least,  fi*om  the  other  forms  of 
septicaemia.     It  is  not  proven  that  the  virulence  of  the 


disease  resides  elsewhere  than  in  the  fluids  of  the  affected 
organs,  nor  is  it  proven  that  it  is  transmissible  by  inocu- 
lation even  from  one  animal  to  another  of  the  same 
species.  The  assertions  that  are  made  concerning  the 
carrying  of  the  disease  by  instruments  suppose  an  ex- 
treme degree  of  virulence  which  is,  to  say  the  least,  very 
doubtful,  and  is  not  supported  by  experiments.  The 
septicaemic  virus,  whatever  it  may  be,  is  destroyed  by  a 
temperature  of  212^  F.,  and  also  by  numerous  antiseptic 
agents.  The  poison  may  be  rendered  innocuous,  even 
after  it  has  been  deposited  upon  the  surface  of  a  wound, 
provided  it  be  as  yet  unabsorbed.  The  difficulty,  how- 
ever— a  difficulty  which  is  often  insuperable — is  to  de- 
stroy this  substance  once  it  has  been  absorbed  and  scat- 
tered through  the  system. 

M.  FouRNiER  thought  that  the  speaker  was  not  quite 
just  in  his  strictures  upon  M.  Duclaux.  There  was 
nothing  in  the  symptomatology  of  the  Aleppo  evil  at  all 
resembling  septicaemia,  and  the  experimenter  was  cer- 
tainly able  to  recognize  the  latter  disease,  especially  when 
he  was  on  the  lookout  for  it  and  had  taken  every  precau- 
tion to  prevent  its  occurrence.  If  the  effects  produced 
depended  upon  the  amount  of  the  culture  fluid  injected, 
it  was  strange  that  they  should  have  varied  so  greatly  ac- 
cording to  the  age  of  the  fluid,  the  same  number  of  cfrops 
being  injected  each  time.  And  again,  if  the  morbid 
symptoms  were  due  to  putrefaction,  the  results  of  inocu- 
lation should  have  become  more  marked  in  proportion 
to  the  age  of  the  fluid.  But  the  exact  contrary  ob- 
tained. 

M.  Colin  held  to  his  original  assertion.  The  presence 
of  decomposing  animal  matters  rendered  the  experiment 
inconclusive.  If  the  same  results  were  obtained  by  the 
injection  of  the  microbes  suspended  in  pure  water,  then 
they  might  justly  be  ascribed  to  the  action  of  the  micro- 
organisms. 

M.  AuGUSTE  VoisiN  then  related  the  histories  of  five 
cases  of 

RETARDED    DEVELOPMENT   IN    CHILDREN, 

in  which  he  had  had  an  opportunit}-  to  study  the  lesions 
found  post-mortem.  Certain  cerebral  troubles  are  al- 
most constantly  associated  with  retarded  ability  to  walk 
in  young  children.  These  are  manifested  by  slowness  in 
learning  to  talk,  awkwardness  in  the  movements  of  the 
upper  extremities,  especially  when  learning  to  write,  in- 
continence of  urine,  malformations  of  the  ears,  etc  In 
every  case  he  fomid  a  more  or  less  complete 

ATROPHY    OF    THE     CONVOLUTIONS     SURROUNDING    THE 
FISSURE  OF   ROLANDO 

at  its  upper  extremity.    The  lesions  were  the  same  in 
kind  and  situation  in  each  of  the  cases  examined  by  him, 
and  differed  only  in  the  degree  of  atrophy. 
The  Academy  then  adjourned. 


Treatment  of  Gonorrhcea  by  Open-wire  Bougies. 
— Dr.  D.  C.  McVail  uses  a  little  contrivance  made  of 
three  wires  soldered  together  at  one  end,  and  bent  into 
the  shape  of  a  sound,  in  the  treatment  of  gonorrhoea. 
The  instrument  is  intended  to  keep  separate  the  inflamed 
mucous  membrane  of  the  urethra,  and  also  to  allow  the 
discharge  to  drain  freely  away  and  not  lie  in  the  passage 
and  give  rise  to  renewed  secretion.  Another  form  has, 
instead  of  the  flanged  extremity,  a  short  length  of  cathe- 
ter-tube attached,  and  to  that  a  short  piece  of  rubber 
tube.  The  solution  to  be  injected  is  introduced  by  a 
syringe,  and  when  quite  full  the  India-rubber  tube  is 
compressed  b^  a  spring  clip,  to  prevent  the  escape  of 
the  fluid.  Within  from  twenty  to  thirty  minutes  the  in- 
jection will  be  almost  wholly  absorbed  by  the  urethral 
walls,  and  then  the  clip  may  be  detached.  These  instru- 
ments are  well  borne  in  the  urethra,  and  the  patient  can 
pursue  his  ordinary  avocations  whUe  wearing  them. — 
British  Medical  Journal. 


78 


THE  MEDICAL  RECORD. 


[July  i9t  1884. 


THE  BIOLOGICAL  SOCIETY  OF  PARIS. 

Stafid  Meetings  June  14,  1SS4, 

M,  F.   Franck,  Presidekt,  in  the  Chj^ir. 

(SpecuJ  Kcport  fur  Tkk  AIadical  Rbcobx9.} 

The  scientific  work  of  the  meeting  was  begun  by  M. 
RocHBFONTAiNE,  who  presented  a  communication  on  be- 
half of  M.  Aphanasieff  upon  the 

TRANSFUSION   OF   PEPTONIZED    BLOOD. 

Since  the  chief  danger  in  this  procedure  lies  in  the 
possible  coagulation  of  the  blood,  and  since  blood  con- 
taining a  certain  proportion  of  peptone  loses  its  coagula- 
bility, the  author  conceived  the  idea  of  using  blood  thus 
prepared  for  transfusion.  The  experiments  were  made 
only  upon  animals,  but  the  results  obtained  were  so  en- 
couraging as  to  warrant  the  extension  of  the  application 
to  man  when  occasion  should  arise. 

M.  Dastre  remarked  upon  the  importance  of  obtain- 
ing perfectly  pure  peptones,  and  also  upon  the  accidents 
sometimes  following  the  introduction  of  peptones  into 
the  circulation. 

M.  Regnard  said  a  few  words  supplementary  to  a 
previous  communication  that  he  had  made  concerning 
the 

effects  of  high  pressure  upon  marine  animals. 

He  had  determined  by  experiments  that  fish  subjected  to 
a  pressure  of  four  hundred  atmospheres  died  from  hydrae- 
mia.  Some  of  the  lower  forms  of  marine  life,  such  as 
star-fish  and  sea  anemones,  could  resist  a  pressure  of 
one  thousand  atmospheres,  but  died  if  this  were  ex- 
ceeded. 

M.  ViGNAT  had,  at  M.  Regnard's  suggestion,  studied 
the  changes  in  the  tissues  caused  by  imbibition  under  high 
pressure,  and  he  recounted  at  some  length  these  alterations 
as  they  occurred  in  the  epithelium,  tendons,  nerves, 
muscles,  and  connective  tissue. 

M.  AuBEAN  spoke  of  the  satisfactory  results  obtained 
by  him  in  producing  anaesthesia  by  a 

MIXTURE  OF  AIR  AND  CHLOROFORM. 

The  experiments  were  made  in  the  service  of  M.  P^an. 
He  had  found  that  a  mixture  in  the  proportion  of  seven 
or  eight  parts  of  chloroform  to  a  hundred  of  air  gave  the 
best  results. 

M.  Dubois  exhibited  in  this  connection  an 

APPARATUS    FOR   THE   INDUCTION    OF   ANAESTHESIA. 

It  was  so  arranged  that  a  mixture  of  air  and  chloro- 
form in  any  desired  strength  could  be  administered. 

M.  Laborde  presented,  in  the  name  of  M.  Vigier,  a 
communication  on 

ORTHOXYPHENYLSULPHUROUS  ACID. 

This  product,  which  is  also  called  by  the  more  pro- 
nounceable name  of  sulpho-carbol,  is  destined,  the 
speaker  said,  to  supplant  carbolic  acid.  It  has  a  much 
less  strong  odor,  and  possesses  antiseptic  properties,  to 
say  the  least,  as  great  as  those  of  carbolic  acid.  It  en- 
joys the  further  advantage  of  being  free  from  poisonous 
properties.  It  had  been  given  to  a  dog  weighing  fifteen 
pounds,  in  the  ^dose  of  two  drachms  per  diem,  with  im- 
punity. 

M.  Regnard  then  made  a  few  remarks  upon 

FERMENTATION. 

At  the  beginning  of  this  process  there  was  a  period  of 
inactivity,  during  which  the  ferment,  of  beer,  for  instance, 
produced  no  effect.  He  had  remarked  that  the  more 
nearly  saturated  was  a  solution  of  sugar,  the  shorter  was 
this  period  of  calm.  He  suggested  that  possibly  the 
beer  ferment  required  some  other  substance  to  excite  it 
to  action. 

After  the  transaction  of  some  general  business  the 
Society  adjourned. 


THE  MEDICAL  SOCIETY  OF  BERLIN, 

Stated  Meetings  June  xr,   1884. 
Professor  Virchow,  President,  in  the  Chair. 

(Special  Report  for  Thb  Medical  Rbcord.) 

The  Society  having  been  called  to  order  by  the  President^ 
Herr  B.  Fraenkel  presented  a  patient  who  had  suffered 
for  four  years  from 

FACIAL   SPASMS, 

involving  the  left  side.  A  varied  treatment  had  beei* 
followed  without  success,  and  finally  the  patient  was  sent 
to  Dr.  Fraenkel  on  account  of  pain  which  she  suffered  in 
the  left  nostril.  A  mild  periostitis  of  the  nasal  bone  was 
found,  which  subsided  again  in  a  few  days.  While  making 
an  examination  with  the  rhinoscope  he  found  that  the 
spasms  were  excited  by  any  irritation  of  the  nasal  raucous 
membrane.  Even  touching  this  membrane  with  the 
sound  was  sufficient  to  induce  the  one-sided  twitchings. 
The  attempt  was  then  made  to  cure  the  spasms  by  ap- 
plications of  the  galvano-cautery  to  the  mucous  mem> 
brane  of  the  nose.  Even  after  the  first  application,  the 
twitchings  became  less  frequent  and  less  violent.  A 
complete  cure  was  obtained  after  five  applications,  made 
especially  to  the  middle  meatus,  from  irritation  of  which 
part  the  spasms  were  most  easily  excited.  The  patient 
had  been  under  observation  for  six  weeks  and  had  had 
no  relapse. 

As  regards  the  changes  observed  in  the  mucous  mem- 
brane, the  speaker  said  that  there  was  nothing  to  be  seen 
but  some  redness  and  a  very  slight  amount  of  swelling. 
Previous  to  the  periostitis,  the  patient  had  never  made 
any  complaint  of  trouble  in  the  nose  which  might  indi- 
cate that  this  was  the  starting-point  of  the  spasms. 
Several  years  ago  the  speaker  had  read  a  paper  at  a  meet- 
ing of  this  Society  upon 

theJrelation  of  asthma  to  diseases  of  the  nose, 

in  which  he  maintained  that  attacks  of  dyspnoea  might  be 
caused  by  a  reflex  action,  excited  by  irritation  of  the 
nasal  mucous  membrane.  Since  that  time  considerable 
attention  has  been  paid  to  the  reflex  neurosis  of  nasal 
origin.  The  case  just  presented  showed  the  excellent 
results  of  a  properly  directed  treatment.  The  patient 
had  suffered  for  four  years  fi-om  an  apparently  intractable 
affection,  which  was  nevertheless  radically  cured  by  five 
sittings  with  the  galvano-cautery. 
Herr  E.  Hahn  then  exhibited  an 

IMMENSE  tumor  OF  THE  NECK 

removed  from  a  man  seventy-four  years  of  age.  It  had 
been  observed  for  the  first  time  thirty  years  before,  and 
was  then  the  size  of  a  walnut,  and  situated  at  the  back 
of  the  neck  over  the  sixth  cervical  vertebra.  At  first 
thercL  was  no  pedicle,  but  as  the  tumor  continued  to  grow 
it  became  pendulous  and  pediculated. 

At  the  time  of  the  operation  the  tumor  weighed  seven- 
teen pounds  and  was  attached  bj^  a  pedicle,  seven  and  a 
half  inches  broad  and  formed  of  integument,  to  the  back 
near  the  fourth  dorsal  vertebra.  The  lower  part  of  the 
growth  reached  down  to  the  level  of  the  fourth  lumbar 
vertebra.  The  skin  was  unchanged  and  was  movable 
over  the  tumor.  The  latter  was  as  hard  as  bone  in  some 
places  and  softer  in  others.  After  removal  it  presented 
on  section  a  bright  yellow  color,  and  was  of  the  consist- 
ency of  firm  lard  in  some  parts,  and  as  hard  as  cartilage 
or  bone  in  others.  These  hard  portions  were  found  tc 
be  concretions  of  lime  salts.  On  the  under  side  of  th< 
tumor  the  skin  and  subcutaneous  cellular  tissue  pre 
sented  the  appearance  of  having  been  sown  with  minuti 
fibromata. 


July  19.  1884.] 


THE  MEDICAL  RECORD. 


79 


HekR  a.  Baginsky  presented  a  specimen  of 

THE    BRAIN   OF  A   CHILD, 

vhjch  be  exhibited  as  showing  that  it  is  possible,  in  cer- 
tain cases  at  least,  to  determine  the 

LOCALIZATION   OF   CEREBRAL   LESIONS 

even  in  very  young  children.  The  little  patient  was  but 
nine  months  old  when  the  first  symptoms  appeared. 
The  pupil  of  the  ri^ht  eye  was  dilated,  and  there  was 
ptosis  on  the  same  side.  The  left  eye  was  rotated  out- 
ward, and  at  the  same  time  its  axis  was  directed  some- 
what downward.  There  was  also  complete  paralysis  of 
the  left  facial  nerve.  The  symptoms  argued  against 
trouble  at  the  base  of  the  brain ;  for  any  lesion  in  this 
situation  so  extensive  as  to  involve  the  motor  oculi  and 
facial  nerves  must  have  given  rise  to  symptoms  of  men- 
ingitis, and  these  were  completely  absent.  Being  thus 
forced  to  the  diagnosis  of  a  central  lesion,  the  location 
could  be  settled  with  tolerable  certainty  in  the  anterior 
portion  of  the  pons,  where  the  centres  for  the  motor 
nerves  of  the  e3'e  are  to  be  found.  And  since  the  ptosis 
and  paralysis  of  the  sphincter  iridis  were  upon  the  right 
side,  the  lesion  was  probably  on  that  side  also.  Further, 
since  syphilis  could  be  excluded,  it  seemed  most  proba- 
ble that  the  lesion  was  tubercular  in  its  character. 
Later  there  were  twitchings  in  the  left  arm  and  leg,  an 
inclination  of  the  head  backward  and  to  the  left,  and  a 
general  curve  of  the  body  to  the  left  side — ^phenomena 
indicative  of  a  lesion  in  die  right  cms  cerebri,  as  well  as 
in  the  anterior  portion  of  the  pons  varolii.  The  disease 
progressed  steadily  until  the  death  of  the  child.  The 
aotopsy  showed  a  considerable  amount  of  fluid  within 
the  cranium,  but  not  a  trace  of  meningitis  or  miliary  tu- 
berculosis. In  the  right  cms  was  found  a  collection  of 
cheesy  matter  extending  forward  to  the  optic  thalamus, 
and  backward  into  and  involving  the  anterior  third  of 
the  pons.  Almost  the  entire  portion  of  the  eras  had 
undergone  this  caseous  degeneration.  There  was  a  red- 
dish brown  zone  surrounding  the  softened  portion  of  the 
farain.  Examination  failed  to  show  the  presence  of  tu- 
bercle bacilli. 
Herr  p.  GtlTERBOCK  then  read  a  paper  upon 

HEREDITARV   SVPHILITIC  JOINT  DISEASES. 

The  author  had  published  an  article  on  this  subject  in 
HbeArMv  fur  Klinische  Chirurgie  for  1878,  in  which 
He  bad  summarized  all  that  was  then  known  about  syphi- 
litic joint  affections  in  young  children.  He  now  desired 
to  supplement  that  article  with  the  conclusions  drawn 
from  a  further  experience  with  the  disease  in  question. 
He  opposed  the  views  of  several  authors,  chiefly  English, 
Aat  syphilitic  joint  lesions  in  children  were  of  common 
occurrence.  He  had  met  with  but  one  case  of  heredi- 
tary syphilis  out  of  everjr  three  hundred  patients  under 
inre  years  of  a^^e.  It  is  important  to  distinguish  this 
fonn  of  joint  disease,  since  the  prognosis,  wiUi  proper 
treatment,  is  ver}'  favorable.  But,  on  the  other  hand, 
the  chances  of  recovery  in  tubercular  arthritis  are  very 
BuIL  The  author  gave  in  detail  {he  histories  of  two  of 
1b  cases,  one  of  which  he  treated  by  corrosive  sublimate 
tabs;  the  other  by  the  internal  administration  of  potas- 
wm  iodide.  Any  operative  interference  in  this  class  of 
fceases  is  usually  productive  of  untoward  results.  In 
o»dnsion,  he  insisted  upon  the  necessity  of  an  early 
^oris  and  the  prompt  institution  of  appropriate 
treatment. 

The  Society  then  adjourned. 


A  SncpLK  Contrivance  for  Making  Camphor 
WATER.-~Dr.  James  Dunworthie,  of  Dobb's  Ferry,  sends 
u  a  bit  of  glass  tubing  in  which  is  pushed  a  piece  of  gum 
^anphor.  This  can  be  thrown  in  a  bottle  of  water  and 
^  sink  to  the  bottom.  The  glass  holds  the  camphor  in 
4c  water. 


THE   ROYAL  IMPERIAL   SOCIETY  OF  PHYSK 
CIANS  IN  VIENNA. 

Staied  Meetings  June  6,  1884. 

Professor  v.  Arlt,  President,  in  the  Chair. 

(Special  Report  for  Thb  Mumcal  Rbooro.) 

The  paper  of  the  evening  was  read  by  Professor 
Billroth,  and  was  chiefly  a  collection  of  statistics  bear- 
ing upon  the  operation  of 

extirpation  of  the  kidney. 

This  operation  was  performed  for  the  first  time  by 
Simon,  fifteen  years  ago.  Since  then,  according  to  the 
tables  prepared  by  Dr.  Schustler,  there  have  been  132 
recorded  cases  of  extirpation  of  the  kidney.  Of  these 
cases,  70  recovered  and  62  died,  a  mortality  of  47  per 
cent.  These  figures  were,  however,  the  speaker  main- 
tained, misleading,  if  used  as  a  basis  for  the  prognosis  of 
individual  cases,  since  the  success  or  failure  of  the  opera- 
tion in  each  case  depended  so  much  upon  circumstances. 

He  then  proceeded  to  dissect  these  statistics,  dividing 
the  cases  into  classes  according  to  the  indications  for 
operation.  In  every  instance  in  which  the  extirpation  of 
the  organ  was,  so  to  speak,  unpremeditated — that  is, 
when  m  operating  for  the  removal  of  an  abdominal  tu- 
mor— ^it  was  found  necessary,  on  account  of  adhesions, 
to  remove  the  kidney  as  well,  a  fatal  result  was  recorded* 

Healthy  kidneys  had  been  removed  in  answer  to  three 
indications :  i.  In  three  cases  of  abdominal  wounds  involv- 
ing the  kidney,  the  injured  organ  had  been  removed.  2. 
In  nine  cases  of  extirpation,  on  account  of  fistulae  of  the 
ureter,  six  had  died.  3.  Fourteen  operations  for  the  re- 
moval of  a  wandering  kidney  have  been  recorded,  six  of 
which  resulted  fatally.  The  author  hoped  that  some 
method  might  yet  be  devised  by  which  the  kidney  could 
be  fixed,  thus  avoiding  the  high  mortality  attending  the 
operation. 

The  extirpation  of  a  diseased  kidney  has  been  under- 
taken for  suppuration  (pyonephrosis,  perinephritis) 
twenty-two  times  with  successful  result ;  on  account  of  a 
tumor,  thirty-three  times  with  twenty  deaths  ;  for  hydro^ 
nephrosis,  nine  times  with  six  recoveries. 

The  author  then  detailed  the  various  steps  in  the  two 
operations  for  extirpation  of  the  kidney,  giving  his  pref- 
erence for  the  lumbar  incision  over  laparotomy. 

Dr.  JuRii  had  removed  a  floating  kidney  success- 
fully, after  having  made  two  futile  attempts  to  fix  it.  The 
patient  recovered,  but  hanged  herself  subsequently,  being 
led  thereto  by  some  family  troubles. 

Dr.  Bergmeister  then  exhibited  a  paitient  with 

CONGENITAL  DERMOID   TUMORS   OF  THE   CORNEA. 

The  two  tumors  were  of  a  reddish  yellow  color,  and 
were  placed  symmetrically  on  the  outer  side  of  the  cornea, 
of  each  eye,  but  were  of  unequal  size.  The  same  patient 
had  also  a 

CONGENITAL   CICATRIX    OF  THE   FACE, 

extending  from  the  left  comer  of  the  mouth  across  the 
cheek  to  the  ear.  The  cicatrix  was  somewhat  sunkea 
and  lightly  stretched,  and  presented  at  its  outer  extrem- 
ity a  little  integumentary  tumor.  The  latter  had  been 
cut  oflC  This  cicatrix,  Dr.  Bergmeister  thought,  was  due. 
to  amniotic  adhesions  to  the  skm.  There  was  one  more, 
point  of  interest  about  the  case,  and  tiiat  was  an 

ASYMMETRY  OF  THE   FACE. 

The  whole  left  side  of  the  face  was  less  developed  thaa 
the  right,  and  the  left  corner  of  the  mouth  was  elevated,, 
probably  from  contraction  of  the  cicatrix. 

Finally,  Professor  Rosenthal  presented  a  patient 
with 

BULBAR   paralysis, 

and  related  his  history  at  length.  The  peculiarity  of  the 
case  consisted  in  the  fact  that  the  sclerotic  atrophy  o 


8o 


THE  MEDICAL  RECORD. 


[July  19,  1884. 


the  nuclei  began  in  the  upper  half  of  the  calamus  scrip- 
torius,  and  then  extended  gradually  downward. 

Professor  Bbnedikt  made  some  further  remarks  on 

CRANIOMETRY, 

and  exhibited  his  instruments,  and  detailed  the  various 
steps  of  the  methods  of  measurement  used  by  him. 

At  the  conclusion  of  this  demonstration  the  Society 
adjourned. 


OUR  LONDON   LEITER. 

(From  our  Special  Correspondent) 

THE  NORTHWEST  LONDON  HOSPITAL — DR.  JOSEPH  ROGERS 
— TYPHOID  IN  SWITZERLAND — DR.  COBBOLD  ON  TRI- 
CHINOSIS  AT  THE   HEALTH    EXHIBITION. 

London,  July  aS,  1884. 

An  event  which  may  be  fraught  with  grave  consequences 
to  the  management  of  hospitals  has  just  occurred  and 
has  excited  no  little  attention.  The  scene  of  action  is 
at  one  of  the  younger  hospitals — the  Northwest  Lon- 
don Hospital.  The  committee  of  this  institution  have 
thought  fit  to  dismiss  one  of  the  surgeons  without  assign- 
ing any  reason.  The  staff  have  resented  this  treatment 
by  resigning  almost  en  masse.  They  have  at  the  same 
time  forwarded  a  written  protest.  It  appears  that  the 
management  is  vested  in  three  ladies,  one  of  whom 
founded  the  hospital.  Of  the  other  two  one  is  also 
acting  as  matron.  The  recent  appointments  to  the  act- 
ing staff  were  made  by  these  ladies  without  consulting 
the  medical  officers  of  the  hospital,  and  the  recent  dis- 
missal of  one  of  the  surgeons  has  been  effected  in  the 
same  manner.  There  is  a  charming  frankness  in  the 
way  in  which  it  is  generally  admitted  that  these  three 
ladies  have  really  appointed  the  staff.  Such  oligarchical 
arrangements  are  not  unknown  in  other  hospitals  than 
that  in  point,  but  are  not  usually  so  openly  acknowledged. 
Frequently,  though,  appointments  to  smaller  hospitals 
are  really  made  by  one  individual — often  the  founder — 
who  quietly  tells  the  committee  what  to  do. 

On  Tuesday  last  a  testimonial  was  presented  to  Dr. 
Jdseph  Rogers,  the  well-known  Poor-law  medical  officer 
and  sanitary  reformer.  The  presentation  took  the  form 
of  a  piece  of  plate  and  a  cheque  for  ;^i5o,  and  the 
several  speakers  referred  to  Dr.  Joseph  Rogers'  well- 
known  services  to  sanitary  science  and  reform. 

Typhoid  fever  is  still  prevalent  in  Switzerland,  especi- 
ally around  Geneva  and  Zurich.  At  this  season  of  the 
year,  when  so  many  tourists  are  going  to  Switzerland,  the 
health  of  that  country  cannot  but  be  of  interest  to  British 
practitioners,  who,  but  for  the  prevalence  of  typhoid, 
might  now  be  sending  their  patients  there.  The  Swiss 
authorities  have  endeavored  to  make  as  light  as  possible 
of  the  matter,  but  in  Zurich  and  Geneva  twenty-six  deaths 
from  typhoid  occurred  during  the  four  weeks  ending 
June  14th. 

Perhaps  the  best  lecture  as  yet  delivered  at  the  Health 
Exhibition,  has  been  that  just  given  by  Dr.  Cobbold  on 
Parasites.  A  large  portion  of  the  lecture  was  devoted 
to  the  subject  of  trichina.  The  life-history  of  the  para- 
site was  described  and  epidemics  of  trichinosis  referred 
to.  Dr.  Cobbold  said  that  the  only  genuine  instance  of 
trichinosis  diagnosed  in  England,  .was  that  in  Cumber- 
land, described  by  Dr.  Dickinson  in  the  Cantor  Lectures. 
Several  persons  were  affected  in  this  outbreak.  All 
other  alleged  outbreaks  were  misinterpretations  of  the 
facts  observed.  A  great  number  of  little  worms  living 
in  various  animals  had  been  described  as  trichinse  by 
persons  not  familiar  with  parasites,  and  to  this  was  due 
the  periodical  **  scares "  got  up  by  newspapers.  As  to 
these  "scares,"  Dr.  Cobbold  remarked  that  ignorant 
writers  in  the  daily  papers  seemed  to  take  pleasure  in 
creating    them.      The  recent    attempt    to    get    up    a 


"mackerel-scare"  fell  rather  flat.  In  regard  to  pre- 
ventive measures,  the  lecturer  said  he  thought  the  ques- 
tion as  to  the  temperature  required  to  kill  the  trichinae 
had  been  set  at  rest  by  the  labors  of  Perroncito,  who 
found  that  cooking  meat  at  120°  F.  was  sufficient  to 
destroy  the  parasites.  M.  Colin  had  shown  that  two  or 
three  weeks  salting  was  sufficient  to  kill  them  in  the 
superficial  parts  of  the  flesh  salted,  but  the  deeper  parts 
might  not  be  reached  for  a  couple  of  months. 


THE  FEEDING   OF    INFANTS,  AND    HOW  TO 
PREPARE  PEPTONIZED  MILK. 

To  THK  EorroK  or  Thk  MsDiqiL  Rboosx>. 

Sir  :  Since  the  publication  of  your  editorial  on  the 
feeding  of  infants,  I  am  receiving  letters  from  physicians 
asking  how  to  peptonize  milk.  I  am  not  surprised  at 
the  interest  awakened  in  the  subject  at  this  season,  when 
so  many  infants  are  sick  from  improper  diet.  Most  in- 
quirers live  at  a  distance.  New  York  physicians  are,  I 
think,  with  few  exceptions,  familiar  with  the  process. 
The  advice  that  I  give  to  my  families  as  regards  the 
preparation  of  milk  is  as  follows  :  Scald  the  milk  when 
it  arrives  in  the  morning,  and  then  place  it  on  ice.  Do 
not  peptonize  more  than  half  a  pint  to  one  pint  at  a 
time;  and  what  the  infant  does  not  take  immediately 
afterward,  should  be  kept  upon  ice  and  surrounded  by 
ice  for  the  second  feeding. 

The  peptonizing  process  is  as  follows  :  Mix  a  powder 
consisting  of  five  grammes  of  Fairchild's  extractum  pan- 
creatis,  and  ten  grains  of  sodium  bicarbonate  in  one 
gill  of  tepid  water.  Add  this  gill  to  one  pint  of  tepid 
milk,  and  place  it  in  a  bowl  in  a  pan  of  water  main- 
tained at  a  temperature  of  100°  or  a  little  over.  In  one 
hour  or  less  time,  the  process  is  completed.  Too  much 
peptonizing  renders  the  milk  bitter.  Some  milk  is  suffi- 
ciently digested  in  thirty  or  forty  minutes,  and  the  nurse 
who  prepares  it  should  occasionally  taste  it  after  the  first 
twenty  minutes,  and  remove  it  from  the  pan  of  warm 
water  before  the  hour  has  expired.  If  the  least  bitterness 
be 'noticed,  the  pancreatic  ferments  are  destroyed  by 
boiling,  and  rendered  inactive  ;  but  not  destroyed  by  a 
temperature  near  that  of  ice.  We  do  not  wish  to  destroy 
the  ferments  but  wish  to  have  them  active  in  the  stomach 
of  the  infant.  Hence,  the  direction  to  place  the  pepton- 
ized milk  on  ice,  instead  of  boiling  it  The  object  is 
to  prepare  for  infants  a  food  which  will  resemble  as 
closely  as  possible  human  milk  in  nutritive  properties 
and  digestibility,  and  peptonized  cow's  milk  appears  to 
be  the  nearest  approach  to  it  yet  obtained. 

The  great  importance  of  the  subject  induces  me  to 
send  to  you  for  publicat  on  the  following  private  letter 
from  Professor  Leeds,  as  perhaps  it  may  aid  in  saving 
life.  It  is  known  to  most  of  your  readers  that  Profes- 
sor Leeds  has  made  more  analyses  of  infants*  foods 
than  any  other  chemist,  and  that  no  one  is  better  able 
to  give  advice  in  dietetics  from  a  chemical  standpoint 
than  he.  The  letter  relates  to  his  remarks  on  infant 
feeding  at  the  meeting  of  the  County  Medical  Associa- 
tion on  June  16,  1884. 

"  Sir  :  The  formulae  which  I  ventured  to  suggest  for 
the  preparation  of  humanized  cow's  milk  was  as  follows  ; 

1  gill  of  cow's  milk,'fresh  and  unskimmed,  i  gill  of  water, 

2  tablespoonfuls  of  rich  cream,  200  grains  of  milk  su^ar, 
i^  grams  of  extractum  pancreatis,  4  grammes  of  sodium 
bicarbonate.  Put  this  in  a  nursing-bottle,  place  the 
bottle  in  water  made  so  warm  that  the  whole  hand 
cannot  be  held  in  it  without  pain  longer  than  one 
minute.  Keep  the  milk  at  this  temperature  exactly 
twenty  minutes.  The  milk  should  be  prepared  just 
before  using.     .    .     .  Yours  truly, 

"Albert  R.  Leeds." 
The  summer  season,  when  infantile  diarrhoea  is  so 
prevalent,  affords  the  opportunity  for  testing  peptonized 
milk,  and  it  is  my  opinion,  from  a  considerable  number 


July  19,  i8«4.] 


THE  MEDICAL  RECORD. 


81 


of  observations,  that  it  is  the  safest  and  best  substitute 
for  breast  milk.  Moreover,  it  appears  to  be  good  food 
for  children  in  the  second  and  third  year,  who  are  sick 
or  have  feeble  digestion.  The  profession  are  indebted  to 
the  Messrs.  Fairchild  for  a  cheap  and  reliable  extractum 
pancreatis.  Yours,  J.  Lewis  Smith,  M.D. 

NwYoK,  July  II,  1884. 


CONCERNING  THE  CONDUCT  OF  THE  EX- 
AMINERS OF  THE  ROYAL  COLLEGE  OF 
SURGEONS,  ENGLAND. 

To  THB  Editok  op  The  Medical  Record. 

Sir:  The  statements  contained  in  your  London  cor- 
respondent's letter  of  May  24th,  respecting  the  examiners 
of  the  Royal  College  of  Surgeons,  are  incredible.  This 
insiouation  that  many  of  them  are  not  gentlemen  is 
grossly  unfair,  but  is  a  little  vague,  no  one  having  yet 
tit  upon  a  quite  satisfactory  definition  of  that  honorable 
title.  But  it  is  certain  that  all  the  examiners  have  been 
and  are  men  of  good  professional  standing  and  attain- 
ments. It  is  quite  incredible  that  a  candidate  could  be 
"dragged  around  the  room  by  his  coat"  when  we  re- 
fflcoiber  that  all  the  examiners  and  examinees  are  in 
one,  not  very  large,  room,  containing  four  tables  and  as 
many  sets  of  examiners.  As  to  the  other  story  of  the 
examiner  who  swore  at  the  candidate  and  kicked  up  his 
heels,  that  is  equally  unlikely.  I  may  say  that  complaints 
have  often  been  made  of  the  examinations  at  the  College 
and  even  of  the  behavior  of  examiners,  but  this  has  never 
refen^  to  anything  but  harshness  of  manner  or  sarcasm, 
vhich  certainly  are  not  desirable  in  an  examiner.  Your 
correspondent's  tales  are  merely  high-flavored  articles  for 
exportation  and  would  only  be  laughed  at  here. 

Yours  faithfully,       Robbrt  Saundbv. 

jKhthall  Stkkbt,  Bikmingham,  Eua, 
June  33,  x884. 


THE  TREATMENT    OF    TAPEWORM— PELLE- 
TIERINE. 

To  THE  Editor  op  The  Medical  Record. 

Sir:  Having  noticed  several  several  inquiries  in  the  columns 
of  your  journal  recently  in  regard  to  the  most  successful 
method  of  disposing  of  tapeworm,  and  having  treated  a 
Qoinber  of  cases  with  the  remedy  which  heads  this  article, 
I  have  concluded  to  give  the  profession  the  benefit  of  my 
experience. 

Few  practitioners  of  large  experience  have  escaped  the 
annoyances  spoken  of  by  your  correspondents.  In  a 
practice  extending  over  twenty-four  years  I  have  treated 
about  twenty  cases,  some  of  which  have  been  very  per- 
plexing, especially  the  /ania  saginati,  or  beef-worm. 
Almost  any  of  the  remedies  ordinarily  used  will  destroy 
4c  Utnia  solium  or  pork-worm.  The  popular  idea  that 
the  foraier,  or  unarmed  variety,  is  the  easiest  to  destroy  is 
erroneous.  1  have  succeeded  with  almost  all  the  reme- 
dies which  1  have  tried  in  destroying  the  solium,  but 
only  occasionally  have  I  been  successful  in  expelling  the 
saginati  entire  with  anything  except  the  pelletierine.  The 
prevalent  opinion  that  the  solium  is  the  more  prevalent 
of  the  two  worms  is  also  a  mistake  as  I  have  met  about 
tiiree  of  the  former  to  one  of  the  latter. 

Case  I. — On  July  2,  1883,  I  administered  pelletierine 
to  a  vigorous  healthy  male  patient,  forty-five  years  of  age. 
He  had  been  afflicted  with  the  worm  for  fifteen  months. 
He  had  taken  June  25,  1882,  fluid  extract  kamela,  and 
passed  about  twenty-five  feet  of  the  worm,  but  no  head. 
Ib  about  three  months  the  ripe  segments  began  to  pass 
^ain.  At  this  time  he  took  fluid  extract  male-fern  with 
a  result  similar  to  the  kamela.  In  December  following, 
^  took  kousso  with  the  same  result,  passing  about 
twnty  feet  of  the  parasite.  In  March  following,  a  mix- 
tnre  of  male-fern  and  kamela  was  given  the  patient  with 
*e  usual  result.     On   July   i,  1883,  twenty   grains   of 

fek*s  tannate  of  pelletierine  was  given.    No  part  of  the 


worm  was  dislodged,  but  upon  the  following  day,  at  5 
o'clock  A.M.,  one  ounce  of  Tanrefs  pelletierine  was  ad- 
ministered, followed  by  four  ounces  of  infusion  of  senna, 
and  at  7  a.m.  the  parasite,  unbroken,  was  passed,  to  the 
great  relief  of  the  patient. 

Case  II. — Wife  of  Case  I.,  contracted  the  disease 
at  the  same  time,  both  being  afllicted  with  the  taenia 
saginati.  Patient  had  similar  treatment  with  no  better 
results.  Pelletierine  was  administered  July  4th,  at  3 
o'clock  A.M.,  followed  in  one  hour  with  the  infusion  of 
senna.  Parasite  passed  entire  at  6  o'clock  a.m.,  making 
the  entire  family  happy. 

Case  III. — Was  that  of  a  German,  aged  fifty-seven. 
Had  been  afflicted  five  years.  Had  taken  medicine  sev- 
eral times  without  success.  Was  unable  to  ascertain 
what  remedies  had  been  used.  Two  years  before  con- 
sulting me  had  an  attack  of  typhoid  fever,  which  lasted 
six  weeks,  during  which  time  several  feet  of  the  worm 
passed.  May  2 1, 1883,  gave  him  fluid  extract  kamela,  after 
the  usual  preparations.  Passed  about  fifteen  feet  of  the 
parasite,  but  no  head.  Three  months  afterward  the  pa- 
tient returned  for  further  treatment.  Gave  him  pelle- 
tierine, but  a  portion  of  it  was  lost  by  vomiting,  repeated 
the  dose  in  three  hours,  followed  by  one  ounce  of  com- 
pound tincture  of  jalap.  Worm  passed  unbroken,  in  one 
hour  after  the  last  dose. 

Case  IV. — Male,  aged  thirty-four ;  carpenter  by  oc- 
cupation ;  had  been  passing  proglottides  about  a  month. 
Had  taken  medicine  from  a  physician  which  pureed  him 
violently,  but  with  no  result.  Gave  him  pelletierine  after 
the  usual  preliminary  treatment,  following  it  with  com- 
pound tincture  of  jalap,  which  did  not  move  bowels  for 
nearly  six  hours.  The  parasite  passed  unbroken  not- 
withstanding the  delay. 

Case  V. — Was  a  young  man,  aged  twenty-one ;  stu- 
dent, who  had  been  afflicted  over  two  years,  but  had 
taken  no  treatment.  Gave  medicine  in  the  usual  way, 
with  a  perfect  success. 

Case  VI. — Was  a  young  lady,  aged  fifteen.  Had  been 
afflicted  two' years.  Had  tsdcen  kamela,  kousso,  and  male- 
fern  without  success,  passing  several  feet  of  the  worm 
at  each  administration,  but  no  head.  I  gave  her  the 
pelletierine  in  the  usual  way,  with  the  same  success  as  in 
the  other  cases. 

All  the  preceding  cases  were  of  the  taenia  saginati. 
Perhaps  one  reason  why  I  have  met  the  saginati  oftener 
than  the  solium  is  because  I  practise  in  a  blue-grass, 
beef-producing  region,  and  where  a  majority  of  the  in- 
habitants eat  their  beef  underdone. 

No  symptoms  were  present  in  any  of  my  cases  which 
would  indicate  the  presence  of  tapeworm,  except  the 
passing  of  the  ripe  segments.  The  patients  had  none  of 
the  symptoms  laid  down  in  the  books.  They  all  enjoyed 
vigorous  health,  and  complained  of  nothing  save  the  an- 
noyance caused  by  passing  the  proglottides,  which  was 
liable  to  occur  at  any  time  without  warning. 

Pelletierine  is  the  alkaloid  of  the  pomegranate  bark, 
and  is  manufactured  by  Charles  Tanret,  64  Rue  de  Ram- 
part, Paris,  France.  Tanret  is  a  student  of  Pelletier, 
who  first  succeeded  in  extracting  the  alkaloids  from  the 
cinchona  bark.  A  desire  to  honor  the  name  of  his  illus- 
trious preceptor  is  sufficient  cause  for  the  name  of  the 
alkaloid. 

It  is  a  pleasant,  safe,  and  speedy  remedy.  When 
stirred  in  a  glass  of  sweetened  water  it  is  as  pleasant  to 
the  taste  as  a  glass  of  lemonade.  It  is  followed  in  a  few 
minutes  by  a  transient  dizziness  or  vertigo,  which  in 
some  of  my  cases  was  quite  severe.  It  should  be  fol- 
lowed in  half  or  three-quarters  of  an  hour  by  a  brisk 
cathartic— compound  tincture  of  jalap  or  infusion  of 
senna.  A  neighboring  practitioner  gave  the  cathartic 
before  administering  the  remedy,  and  the  worm  was  ex- 
pelled in  less  than  an  hour  after  taking  the  pelletierine, 
but  it  was  a  taenia  solium.  G.  C.  Smyths,  M.D. 

GRimNCASTLB,  InIX, 

June  24,  1884. 


82 


THE  MEDICAL  RECORD. 


[July  19,  1884* 


To  THB  Editor  op  Thk  Medical  Record. 

Sir  :  In  the  Medical  Record  of  June  21st,  Dr.  Thomas 
Wilde  offers  a  prescription  for  the  removal  of  tape-worm, 
which  has  so  great  a  similarity  to  a  mode  of  treatment  used 
by  myself  for  several  years  with  such  unvarying  success 
that  I  am  induced  to  offer  it  to  you  as  an  appendix  to 
Dr.  Wilde's  article.  It  has,  however,  this  advantage, 
that  the  time  required  to  produce  its  effect  is  only  about 
twelve  hours,  instead  of  being  drawn  out  for  a  week. 
The  formula,  I  believe,  originated  with  Dr.  A.  J.  Shafish, 
of  Washington,  D.  C,  and  was  published  over  the  signa- 
ture of  Dr.  Trumbull  in  the  Medical  and  Surgical  Re- 
porter. My  attention  was  called  to  it  by  Mr.  Byron 
^tednian,  a  most  excellent  pharmacist  of  this  city,  who 
obtained  it  from  the  records  of  the  Brooklyn  Dispensary, 
with  which  institution  he  was  at  one  time  connected, 
who  prepares  it  with  more  than  ordinary  skill.  During 
the  past  year  I  have  treated  eleven  cases,  in  each  and 
every  case  the  entire  worm  has  been  expelled  at  once. 
In  the  majority  of  the  cases  the  head  has  been  discov- 
ered, while  in  those  in  which  it  was  not  found  the  tenuity  of 
the  cephalic  extremity  left  no  doubt  in  my  mind  but  that 
the  head  had  passed  away  and  been  lost  among  the  fecal 
<lischarges.  At  any  rate,  the  non-return  of  the  parasite 
in  those  cases  in  which  the  head  was  not  found  proves 
the  destruction  of  the  unwelcome  tenant.  I  have  used 
it  in  delicate  women  and  children,  and  beyond  a  tem- 
pora.ry  prostration  have  witnessed  no  bad  effects.  My 
usual  course  is  to  ask  the  patient  when  he  can  con- 
veniently attend  to  the  removal,  and  setting  a  day,  mak- 
ing no  change  in  his  diet  whatever,  give  at  bed-time  half 
an  ounce  of  Rochelle  salts.  The  following  morning  at 
about  ten  o'clock — all  food  having  been  omitted — I  give 
^he  following,  prepared  as  I  shall  state  : 

$.  Cort.  rad.  pomegranate 5  ss. 

Pumpkin  seeds f  j. 

Kernel  of  ergot 3  ss. 

Ethereal  ext.  male-fern f  3  j. 

Gum  arable 3  ij- 

Croton  oil gtt.  ij. 

Aquae f  S  vj. 

M. 

In  about  two  hours  the  worm  is  expelled.  The  success 
of  this  mode  has  been  unvar3ring.  The  foregoing  draught 
IS  intensely  bitter,  and  tends  to  nauseate,  but  by  direct- 
ing the  patient  to  drink  it  quickly  and  lie  down  imme- 
diately, the  tendency  to  vomit  is  arrested.  After  the 
worm  is  discharged,  I  order  a  strong  milk-punch,  and  if 
the  bowels  seem  irritable  or  are  painful,  a  dose  of  opium 
or  morphia  removes  the  trouble.  In  a  day  or  two  an 
iron  tonic  is  given. 

In  the  preparation  of  the  anthelmintic  bruise  the  bark, 
pumpkin  seeds,  and  ergot  in  a  mortar  to  moderately  fine 
powder,  heat  for  half  an  hour  in  the  water  in  a  water- 
bath,  strain,  and  on  the  residuum  pour  enough  hot  water 
and  strain  with  pressure  to  bring  the  quantity  of  strained 
fluid  up  to  six  ounces.  Put  the  oil  into  the  gum  arable, 
add  the  male-fern — emulsionize  the  whole.  With  care  a 
6ne  emulsion  is  produced. 

I  am  looking  for  a  remedy  against  **pin-worms**  which 
-shall  prove  as  successful  and  prompt  as  is  the  one  I  have 
igiven  you  against  the  taenia.       H.  Lvle  Smith,  M.D. 

Hudson,  N.  Y.,  June  33,  1884. 

To  TKB  Emtor  of  Tub  Mbdical  Rbcordw 

Sir  :  In  response  to  a  request  of  a  subscriber  for  the 
treatment  of  tapeworm  I  will  say  that  I  once  saw  in  an 
bid  number  of  Braithwaii^s  Retrospect  an  item  advising 
the  use  of  creasote  in  persistent  cases,  since  that  I  have 
used  that  agent  after  all  others  had  failed,  with  invariably 
successful  results.  I  have  given  one  drop  in  an  emulsion 
of  acacia  three  times  daily  for  two  days,  then  increased  to 
two  drops  three  times  daily  for  two  days,  then  to  three 
<lrops  for  two  or  three  days,  when  the  head  has  universally 
•come  away.  Finlev  Ellingwood,  M.D. 

Mantsno,  III.,  June  xj,  2884. 


To  THB  Editor  op  Thb  Mbdical  Rkcord. 

Sir  :  For  the  benefit  of  your  subscriber  who  seeks  infor- 
mation upon  the  best  treatment  of  tapeworm,  I  would 
suggest  to  him  the  use  of  Tanret's  pellerierine.  I  have 
used  the  remedy  in  six  cases,  five  of  them  being  successful. 
Fougera  &  Co.,  New  York  City,  are  the  agenU  for 
Tanret's  pelletierine  in  this  country. 

Yours,  very  respectfully,    H.  Wilfert,  M.D. 

Cincinnati,  June  x6,  1884. 

To  thb  Editor  op^Thb  Mbdical  Rbcord. 

Sir:  In  reply  to  a  request  of  one  of  your  subscribers 
(Medical  Record,  p.  682,  June  14,  1884),  and  for  the 
information  of  those  interested  in  the  subject,  a  mode 
of  treatment  for  tapeworm  is  given  below  which  has 
proved  in  my  hands  to  be  better  than  any  other,  and  has 
have  given  most  satisfactory  results.  A  reliable  remedy 
for  the  relief  of  tapeworm  is  a  valuable  addition  to  the 
therapeutical  knowledge  of  every  general  practitioner, 
for  whatever  the  opinion  of  medical  minds  may  be  about 
the  severity  of  disturbances  caused  directly  by  the  pre- 
sence of  parasites  in  the  alimentary  canal,  it  cannot 
be  disputed  that  laymen  attribute  great  importance  to 
their  presence.  I  have  seen  a  large  number  of  cases  of 
tapeworm,  and  have  given  a  fair  trial  to  the  variety  of 
remedies  which  are  generally  administered  in  such  cases, 
including  the  infusion  of  pomegranate  root,  as  recom- 
mended by  Dr.  Thomas  Wilde  (Medical  Record,  May 
31,  1884).  The  principal  objection  to  the  use  of  the 
latter  is  its  unpleasant  taste  and  the  large  amount  of 
fluid  which  has  to  be  taken ;  in  a  number  of  cases  where 
the  pomegranate  infusion  had  been  used  it  produced 
violent  emesis,  and  some  patients  were  unable  to  retain 
it,  even  in  small  doses.  In  four  cases  out  of  fifteen  the 
entire  worm  had  been  expelled  and  the  head  found,  but 
almost  all  the  patients  complained  of  the  harsh  treatment. 
The  treatment  which  has  been  followed  by  the  best 
results  is  a  simple  one,  any  reliable  apothecary  can  pre- 
pare the  prescription,  and  patients  will  take  the  medi- 
cine without  difficulty.  Although  it  is  not  essential  to 
have  the  patient  fast  for  any  length  of  time,  still  it  is 
advisable  to  allow  only  moderately  of  food  during  the 
afternoon  and  evening  of  the  first  day,  and  to  abstain 
from  food  entirely  while  taking  the  medicine  in  the 
morning  from  8  to  10  a.  m.  The  following  are  the  pre- 
scriptions to  be  given  as  directed  : 

8 .  Hydr.  chlor.  mite gr.  x. 

Pulv.  jalapse 3  ss. 

Pulv.  aromat gr.  x. 

M.  Ft.  pulv.  No.  2. 

S. — Take  one  powder  at  4  p.m.  and  the  other  one  at 
bed-time. 

5.  Ext.  male-fern  ether 3  iij. 

Ext.  sennae  fid 3  iij. 

Ext.  hyoscyami  fid., 

Tr.  menth.  pip aa   3  ss. 

M.  Ft.  mist. 

S. — ^Take  one  teaspoonful  (good  sized)  every  half 
hour — to  commence  at  8  a.m.  the  day  after  the  powders 
have  been  taken. 

The  use  of  hydr.  chlor.  mite  as  a  preparatory  remedy 
has  been  suggested  by  Dr.  R.  Kuchenmeister  in  Dresd«P.  . 
Paul  H.  Kretschmar,  M.D./t 

Brooklyn,  N.  V.  JRI 

P 

Nux  Vomica  as  a  Galactagogue.  —  Dr.  Poln<^da 
Arango  speaks  very  highly  of  the  good  effect  ofonCaux 
vomica  as  a  stimulant  to  the  secretion  of  milk.  He^tl) gives 
ten  drops  of  the  tincture  three  times  a  day,  and  exi  just^ 
its  galactagogue  properties  by  its  action  on  the  j  ^' 
mary  gland,  exciting  it  to  secretion,  and  by  its  stimufi*'  M 
action  on  the  stomach  facilitating  digestion.  He  r^  sOgcom- 
mends  strychnia  in  recent  cases  of  complete  suppr)ii2e<!^oA 
of  the  secretion. — London  Medical  Record.  4mbei 


July  19. 1884.] 


THE  MEDICAL  RECORD. 


83 


THE  QUESTION  OF  THE  FLORIDA  CLIMATE. 

To  TUB  Editqr  or  TUB  Mboicax.  Rbookd. 

Sir  :  On  April  26th  last  you  published  in  The  Record 
a  letter  from  Dr.  Boyland,  of  Baltimore,  upon  "  Florida 
as  a  Health  Resort"  As  some  of  his  statements  were 
50  opposite  to  my  observations,  I  felt  like  rushing  into 
print  and  criticism  of  the  Doctor's  paper.  But  as  it  is 
now  over  two  years  since  I  was  last  in  Florida,  and  not 
knowing  what  wonderful  changes  might  have  occurred 
there  meantime,  I  immediately  wrote  my  friend  Dr. 
Phillips,  of  Gainesville,  Fla.,  for  a  few  statistics.  Un- 
avoidable accident  delayed  his  answer  and  consequently 
this  of  mine.  His  letter  is  now  before  me,  but  as  time 
cures  almost  every  curable  thing,  my  first  impulse  to 
criticise  shall  be  modified  and  confined  to  a  few  items 
relative  to  the  respective  advantages  as  sanitariums  of 
{Gainesville  and  Cedar  Key  (not  "  Keys  ").  Dr.  Boyland 
disparages  Gainesville  by  complaining  of  its  level  surface 
and  defective  drainage,  also  on  account  of  the  vast  num- 
ber of  consumptives  whom  he  seems  to  believe  do  con- 
gregate there  in  shoals  and  nations,  and  the  almost  daily 
deaths  among  whom  (as  he  says)  exert  a  **  deleterious 
effect  upon  other  and  non-phthisical  cases.''  Bad !  bad 
enough,  if  true,  but  Dr.  Phillips  says  (and  I  will  vouch 
for  h^  truthfulness)  '^  there  were  not  to  exceed  six  cases 
of  deaths  among  the  visitors  at  Gainesville  from  Nov- 
ember, 1883,  to  May,  1884." 

How  about  **  the  almost  daily  deaths  "  reported  by  Dr. 
Boyland  ?  As  to  the  level  surface  and  defective  drainage, 
I  can  speak  for  myself.  I  say  the  ground  is  rolling,  that 
most  of  the  streams  are  situated  in  deep  ravines,  and  the 
currents  lively.  I  say  further  that  Gainesville  is  drained 
by  a  natural  sink,  about  two  miles  south  of  the  town. 
The  streams  of  the  surrounding  districts  pour  down  the 
j^eat  throat  of  this  inlet  to  the  vast  cavernous  passage 
below  the  limestone  stratum;  where  the  water  again 
comes  to  the  surface  no  one  knows,  but  from  the  direc- 
tion of  the  line  of  depressions,  marking  the  course  of  the 
subterranean  stream,  it  probably  runs  north  and  directly 
under  Gainesville^  for  about  two  miles  north  of  the  town 
is  one  of  these  depressions  (and  the  largest  of  them  all) 
where  one  can  go  down  dry-shod  from  the  pine-covered 
sand  above,  over  one  hundred  feet  to  the  coral  rock  bed 
or  backbone  of  the  State.  So  much  for  the  level  surface 
and  want  of  drainage  of  Gainesville. 

Now,  as  the  Doctor  recommends  Cedar  Key  to  those 
who  desire  a  seaboard  resort,  I  must  conjecture  tliat  his 
icquamtance  with  that  city  is  secondary,  also  that  his  in- 
formant (if  informant  he  had)  does  not  eliminate  truth 
freely. 

The  drainage  of  Cedar  Key  is  largely  into  the  wells, 
the  air  is  redolent  of  bilge- water  and  putrid  things. 
With  the  periodic  winds,  quotidian  fogs,  perennial  fleas, 
nocturnal  mosquitoes,  with  nothing  to  please  the  eye, 
ererydiing  to  offend  the  nose,  and  not  one  drop  of  clean 
well-water  to  cool  the  mouth,  I  would  recommend  Cedar 
Key  to  no  one,  except  a  scavenger,  and  him  one  of  about 
&e  nine  hundred  and  ninety-ninth  "  stage."  As  a  sani- 
tarium I  prefer  Gainesville  to  any  other  town  in  Florida 
bown  to  me ;  Cedar  Key  I  would  place  last  in  the  fullest 
catalogue.  Wm.  B.  Bradner,  M.D. 

Wunnac,  N.  Y.,  May  a6, 1884. 


SHALL  OFFICERS  OF  THE  ARMY  ENGAGE  IN 
PRIVATE  PRACTICE. 

To  THE  Editor  op  Ths  Mbdical  Rbcoko. 

FSdl:  Some  time  ago  I  wrote  to  the  Surgeon-General  of 
I  ie  Army  for  information  respecting  some  points  of  prac- 
tical importance  to  physicians,  and  in  reply  received 
rd  that  not  only  was  there  no  rule  or  regulation  pre- 
itiiig  post  surgeons  from  engaging  in  general  practice, 
iltt  that  it  was  his  custom  to  advise  post  surgeons  to 
waU  the  practice  they  could  outside,  so  that  they  might 
yttg-m  rusty. 


As  this  seems  to  me  anything  but  a  fair  and  proper 
course  to  pursue  ;  and  as  an  earnest  protest  on  my  part 
has  received  absolutely  no  notice  whatsoever,  I  wish 
through  your  columns  to  inform  those  physicians  who 
are  so  unfortunate  as  to  live  where  army  surgeons  are 
stationed,  of  just  what  they  may  reasonably  expect.  If 
there  is  no  impropriety,  not  to  use  a  harsher  term,  in 
attempting  to  secure  outside  practice, while  drawing  full 
and  presumably  adequate  pay  from  the  Government, 
then  I  must  confess  myself  so  mentally  obtuse  as  not  to 
perceive  it. 

In  the  first  place  it  is  unfair  competition.  The  army 
surgeon  is  backed  by  an  assured  salary.  The  offiqe  he 
occupies  and  the  horse  and  buggy  he  uses  are  in  part 
paid  for  by  the  very  physicians  against  whom  he  comes 
in  competition.  To  the  military  medical  mind  this  may 
seem  fair  and  honorable.  To  the  civilian,  however,  it 
certainly  does  not. 

In  the  second  place,  the  fear  t?iat  the  army  surgeons 
may  grow  rusty  affords  no  manner  of  excuse  for  pirat- 
ing outside  of  the  post.  If  there  is  not  enough  for  the 
surgeons  in  the  army  to  do,  then  cut  down  the  num- 
ber ;  or  else  give  them  more  soldiers  to  look  after.  It 
is  the  Government's  fault  that  there  are  too  many  sur- 
geons for  the  number  of  soldiers.  Let  the  Government 
remedy  that  and  not  advise  their  subordinates  to  encroach 
on  ground  not  legitimately  their  own.  Have  civil  prac- 
titioners no  rights  as  opposed  to  salaried  Government 
officers?  Were  there  a  dearth  of  local  physicians  an 
army  surgeon  might  be  excused  for  answering  calls  in 
emergencies.  Such  conditions,  however,  do  not  obtain 
here  in  the  East 

I  hesitate  to  believe  that  the  majority  of  army  sur- 
geons would  follow  any  such  advice  as  has  emanated 
from  the  Surgeon- General,  having  been  informed  by 
gentlemen  of  the  army  that  practising  outside  of  posts 
has  not  been  customary  in  the  past,  except  in  such  places 
where  physicians  were  few  and  far  between,  as  in  the  far 
West ;  and  moreover  such  practice  has  always  been  re- 
garded as  not  strictly  fair  and  honorable,  except  under 
the  exceptional  conditions  just  mentioned. 
Very  truly  yours, 

John  G.  Stanton,  M.D. 

Nkw  London.  Conn., 
July  8,  Z884. 

^vm^  and  S^tig  ^jettrs. 

Official  List  if  Conges  in  the  Stations  astd  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army, 
from  July  6  to  July  12,  1884. 

Perin,  Glover.  To  be  Assistant  Surgeon-General, 
with  rank  of  Colonel,  promotion  to  date  from  July  2, 
1884. 

Smith,  Andrew  K.  To  be  Surgeon,  with  rank  of 
Lieutenant-Colonel,  promotion  to  date  from  July  2, 
1884. 

MiDDLETON,  Passmore.  To  be  Surgeon,  with  rank 
of  Major,  promotion  to  date  from  July  2,  1884. 

Clements,  B.  A.,  Major  and  Surgeon.  Also  directed 
to  relieve  Surgeon  J.  P.  Wright  of  his  duties  as  Acting 
Medical  Director,  Department  of  the  Missouri.  S.  O. 
138,  par.  I,  Headquarters  Department  of  Missouri, 
July  8,  1884. 

Promotions. — ^To  be  Assistant  Surgeons,  with  the  rank 
of  Captain  after  five  years'  service,  m  accordance  with 
the  Act  of  Congress  of  June  23,  1874.  Assistant  Sur- 
geons John  J.  Kane,  John  M.  Banister,  Aaron  H. 
Appel,  Charles  Richard,  W.  Fitzhugh  Carter,  June  3, 
1884. 

Birmingham,  H.  P.,  First  Lieutenant  and  Assistant 
Surgeon.  From  Fort  Bayard,  N.  M.,  to  Fort  Bliss, 
Texas.  S.  O.  137,  par.  3,  Heaidquarters  Department  of 
the  Missouri,  July  3,  1884. 


84 


THE  MEDICAL  RECORD. 


[July  19, 1884. 


Official  List  of  Changes  in  the  Medical  Carps  of  the  U.  S. 
JVavy,  during  the  weeh  ending  July  is,  1884. 

LuMSDEN,  G.  P.,  Passed  Assistant  Surgeon.  Ordered 
to  U.  S.  S.  Wyandotte. 

Persons,  R.  C,  Passed  Assistant  Surgeon.  Detached 
from  U.  S.  S.  Wyandotte  and  placed  on  waiting  orders. 


Official  List  of  Changes  of  Stations  and  Duties  of  Medical 
Officers  of  the  U,  5.  Marine  Hospital  Service^  April  i 
to  June  30,  1884. 

Bailhache,  p.  H.,  Surgeon.  Detailed  as  chairman  of 
Board  to  examine  candidate  for  appointment  into  the 
Revenue  Marine  Service,  May  17,  1884. 

Vansant,  John,  Surgeon.  To  proceed  to  Empire  City, 
Oregon,  as  Inspector,  April  2,  1884. 

HuTTON,  W.  H.  H.,  Surgeon.  Granted  leave  of  ab- 
sence for  twenty-five  days,  May  14  and  June  9,  1884* 

Miller,  T.  W.,  Surgeon.  Granted  leave  of  absence 
to  attend  the  meeting  of  the  American  Medical  Associa- 
tion, May  I.  To  proceed  to  Pittsburg,  Pa.,  Ashtabula, 
O.,  Buffalo,  N.  Y.,  and  Detroit,  Mich.,  as  Inspector,  May 
10,  1884. 

Wyman,  Walter,  Surgeon.  To  proceed  to  Crisfield, 
Md.,  as  Inspector,  April  1 1,  1884.  Detailed 'as  president 
of  Board  for  physical  examination  of  candidates  for  ap- 
pointment as  cadets  in  the  Revenue  Marine  Service,  May 
20,  1884.  To  examine  cadet-graduates  Revenue  Marine 
Service  as  to  physical  qualifications.  May  31,  1884.  De- 
tailed as  member  of  Commission  to  inspect  United  States 
buildings  at  Quarantine  Station  on  the  Delaware  River, 
June  16,  1884.  Detailed  to  represent  the  Marine  Hos- 
pital Service  as  Delegate  to  the  American  Medical  Asso- 
ciation, April  17,  1884. 

Austin,  H.  W.,  Surgeon.  Granted  leave  of  absence 
to  attend  the  meeting  of  the  American  Medical  Asssocia- 
tion,  May  2,  1884. 

Gassaway,  J.  M.,  Surgeon.  When  relieved  by  Passed 
Assistant  Surgeon  Mead,  to  proceed  to  Portland,  Me.,  and 
assume  charge  of  the  Service,  April  16,  1884.  Granted 
leave  of  absence  for  thirty  days,  May  28,  T884. 

Stoner,  G.  W.,  Passed  Assistant  Surgeon.  When  re- 
lieved by  Surgeon  Gassaway,  to  proceed  to  Cairo,  111.,  and 
assume  charge  of  the  Service,  April  16,  1884.  When 
relieved  by  Surgeon  Gassaway,  to  report  in  person  to  the 
Surgeon-General,  June  20,  1884. 

Irwin,  Fairfax,  Passed  Assbtant  Surgeon.  Granted 
leave  of  absence  for  twenty-one  days,  June  19,  1884. 

Mead,  F.  W.,  Passed  Assistant  Surgeon.  When  re- 
lieved by  Assistant  Surgeon  Devan,  to  proceed  to  Phila- 
delphia, Pa.,  and  assume  charge  of  the  Service,  April  16, 
1884.  Detailed  as  recorder  of.  Board  for  physical  exami- 
nation of  candidates  for  appointment  as  cadets  in  the 
Revenue  Marine  Service,  May  20,  1884. 

Carter,  H.  R.,  Passed  Assistant  Surgeon.  To  inspect 
unserviceable  property  at  the  San  Francisco  Hospital, 
May  24,  1884. 

Wheeler,  W.  A.,  Passed  Assistant  Surgeon.  To  in- 
spect unserviceable  property  at  the  Chicago  Hospital, 
May  24,  1884. 

Benson,  J.  A.,  Passed  Assistant  Surgeon.  Granted 
leave  of  absence  for  thirty  days,  April  14,  1884.  When 
relieved  by  Passed  Assistant  Surgeon  Stoner,  to  report  to 
him  for  temporary  duty.  May  19,  1884. 

Banks,  C.  £.,  Passed  Assistant  Surgeon.  Detailed  as 
member  of  Board  to  examine  physically  candidate  for  ap- 
pointment into  the  Revenue  Marine  Service,  May  17, 
1884.  To  inspect  unserviceable  property  at  Baltimore, 
Md.,  New  York,  N.  Y.,  and  Boston,  Mass.,  May  26  and 
June  2, 1884. 

Bennett,  P.  H.,  Assistant  Surgeon.  Granted  leave 
of  absence  for  twenty  days,  June  28,  1884. 


Devan,  S.  C,  Assistant  Surgeon.  To  proceed  to  Port 
Townssnd,  W.  T.,  relieve  Passed  Assistant  Surgeon 
Mead,  and  assume  charge  of  the  Service,  April  14,  igg. 

Urquhart,  F.  M.,  Assistant  Surgeon.  Granted  leave 
of  absence  for  thirty  days.  May  22,  1884. 

Yemans,  H.  W.,  Assistant  Surgeon.  To  report  to 
Captain  M.  A.  Healey  for  duty  as  Medical  Officer  during 
cruise  of  Revenue  Cutter  Corwin,  April  16, 1884. 

Glenn  AN,  A.  H.,  Assistant  Surgeon.  To  proceed  to 
Mobile,  Ala.,  for  temporary  duty  during  sickness  of 
Passed  Assistant  Surgeon  Goldsborough,  June  17,  1884, 

Brooks,  Stephen  D.,  M.D.,  Massachusetts,  having 
passed  the  examination  required  by  the  Regulations,  was 
appointed  an  Assistant  Surgeon  by  the  Secretary  of  the 
Treasury,  May  15,  1884.  (Dr.  Brooks  had  previously 
served  as  an  Acting  Assistant  Surgeon  from  March,  1883, 
to  May,  1884). 

ptiedicaX  Items. 

C0MTA010U8  D18KASBS — ^WuKLY  Statkiibnt.— Re-' 
port  of  cases  and  deaths  from  contagioai  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  July  12,  18S4 : 


WeekEndinff 


Ctues, 

July  5, 1884.... 
July  12,  1884. ., 

Deaths. 
July  5, 1884..  . 
July  12,  1884.. 


I 


156 
187 


A  Case  of  Successful  Replantation  of  a  Tooth 
is  recorded  in  the  Weekly  Medical  Reidew  by  Dr.  A.  B. 
Bamette.  He  writes  that  he  extracted  the  tooth,  cleaned 
the  cavity,  washed  the  tooth  well  and  put  it  back.  Inside 
of  a  month  it  was  firm  and  he  had  it  filled. 

The  Cholera  Germ  and  the  Local  and  Time 
Factors. — Professor  von  Pettenkofer,  of  Munich,  has 
written  an  article  in  the  Neuesten  Nachrichien  in  which 
he  shows  that  a  bacillus  or  germ  is  not  alone  sufficient 
to  explain  the  causation  and  transmission  of  cholera. 
There  must  be  certain  conditions  of  season  and  soil 
which  favor  its  development.  These  he  calls  the  '*  local 
and  time  factors." 

F.  Hebra's  Prescription  for  Baldness. — ft.  Tinct. 
macis,  5  grammes;  olei  dulcis,  50  grammes.     M. 

YvoN*s  Paraldehyde  Elixir  for  Insomnia. — 9- 
Paraldehyde,  10  grammes ;  alcohol  at  90^,  40  grammes; 
tinct.  vanillas,  2  grammes ;  aquse,  30  grammes ;  syr. 
simpl.,  60  grammes.     M.     Dose  3  j-  to  3  ij- 

Removal  of  a  Wandering  Spleen. — According  to 
an  account  published  in  the  American  Medical  Jiofirnal 
of  July,  1884,  Dr.  E.  Younkin,  of  St.  Louis,  has  success- 
fully removed  a  spleen,  which  had  committed  the  offence 
of  being  dislocated  and  causing  distressing  pains.  The 
organ  was,  before  removal,  two  or  three  times  larger 
than  normal.  After  removal  its  parenchyma  was  found 
to  be  healthy.  The  patient  was  a  married  woman,  aged 
thirty-two,  of  slight  build,  and  was  in  tolerably  good 
health. 

The  Last  Form  of  Mercury  recommended  for  me- 
dicinal use  is  the  hydrarg^m  tannicum  oxydulatum, 
which  has  been  prepared  in  the  laboratory  of  Professor 
Ludwig,  of  Vienna.  It  is  a  greenish,  tasteless  powder. 
Dose,  o.i  gramme. 


The   Medical   Rec 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  36,  Ho.  4 


New  York,  July  26,  1884 


Whole  No.  7x6 


SOME  REMARKS   ON    AFFECTIONS   OF  THE 
HEART. 

By  J.  MILNER   FOTHERGILL,   M.D.  Edin.,   Hon.    M.D. 
Rush  Med.  Coll.,  Jll. 

^ifsooATB  nuxm  or  tub  oollsgb  or  physicians  or  philadblphia,  physician 

TO  TflB  QTY  OF  UHfDON  HOSPITAL  FOR  CISKASBS  OP  THB  CHBST. 

IV. 

CARDIAC   NEUROSES. 

YThex  a  patient  presents  himself,  and  still  more  herself, 
before  a  doct<M:  at  first-hand,  complaining  of  the  heart, 
''^  is  all  Buckingham  Palace  to  a  sentry-box  the  case  is 
one  of  a  cardiac  neurosis,  and  not  organic  disease.  It  is 
some  ontcome  of  the  latter,  as  shortness  of  breath,  for 
iostance,  which  leads  the  subject  to  the  doctor's  office 
then  the  case  is  one  of  organic  disease.  Then,  when 
die  patient  complains  of  pain  at  or  near  the  heart,  re- 
member disease  of  the  heart  does  not  produce  pain. 
Aogina  pectoris  is  the  only  pain  linked  with  disease  of 
the  heart  or  arteries.  You  can  at  once  say,  "  Pain  has 
nothing  to  do  with  heart  disease."  The  patient  ma^ 
lave  some  heart  trouble  as  a  coincident  matter ;  but,  if 
10,  this  has  no  relation  to  the  pain  complained  of.  But 
Wever  clear  you  may  be  about  the  matter  yourself,  you 
liU  find  it  no  easy  matter  to  convince  the  patient 
Baving  laid  down  these  two  broad  rules,  the  different 
cardiac  neuroses  may  now  be  sketched  in  outline. 

First  comes  palpitation.  Palpitation  linked  with  efifort 
isasaaliy  muscular  adynamy,  and  points  to  the  heart  as  a 
muscle.  Palpitation  coming  on  at  other  times  than  when 
eft»t  is  made  points  either  to  vaso-motor  disturbance 
(goaty),  or  is  neurosal.  When  a  lady  is  wakened  up  in  the 
i^t  widi  her  heart  beating  violently,  and  yet  now  and 
again  halts,  as  if  it  was  going  to  stop,  she  is  naturally 
very  nnich  alarmed.  And  yet  usually  she  need  not  be 
aknned.  Such  an  experience  is  common  with  women 
at  the  menopause ;  and  there  may  or  may  not  be  an 
asthenic  condition  of  the  heart-wall  present.  There  may 
ke  DO  gout  in  the  case ;  often  there  is.  Very  often  in 
9^  cases  there  is  a  weak  state  of  the  heart-wall  which 
nquires  attending  to  by  appropriate  measures.  In  some 
the  attacks  are  due  to  some  derangement  in  the  in- 
Knradon  of  the  heart,  connected  with  the  accelerator 
of  the  vagus.  A  start  will  cause  palpitation  in 
■any  persons,  and  especially  females  liable  thereto.  The 
Kxral  act  will  not  uncommonly  set  up  violent  palpitation, 
continence  may  bring  on  paroxysms  of  palpitation, 
efiared  by  intercourse.  Indulgence  in  tea,  and  to  a 
extent  in  coffee^  commonly  leads  to  a  condition  of 
heart  where  palpitation  is  experienced  on  slight 
In  exophthalmic  goitre  (Basedow's  disease)  a 
It  action  of  the  heart  is  one  of  its  main  features, 
dwrea  tumultuous  action  of  the  heart  is  usually  pres- 
L  But  among  all  these  conditions  palpitation  pro- 
ved by  efifort  is  what  puts  you  on  the  qui  vive  for 
'iSsease"  as  compared  to  *' disorder"  of  the  heart. 
Then  palpitation  may  be  set  up  by  far-away  irritation, 
btkin  tells  of  a  case  where  it  was  set  up  by  a  floating 
It  is  common  with  a  misplaced  womb,  and  dis- 
when  the  uterus  is  restored  to  its  normal  posi- 
I  haye  seen  it  linked  with  prostatic  trouble,  and 
vith  anal  eczema.     When  paroxysms  of  palpitation 


come  on  without  obvious  relationship,  always  institute  a 
careful  search;  if  you  can  find  something,  and  put  that 
something  right,  you  will  usually  find  the  palpitation  take 
its  departure. 

There  is  one  form  of  palpitation  which  has  such  distinct 
relations,  and  is  so  commonly  met  with  (when  the  doctor 
has  learned  to  see  it),  that  it  deserves  a  few  words.     It 
is  ovarian  in  its  origin.     The  patient,  usually  a  woman 
of  child-bearing  age,  complains  of  more  or  fewer  of  the 
following  symptoms,  sometimes  one  being  more  prom- 
inent than  the  other :    She  has  pain  in  her  side  with 
palpitation.     She  has  vertical  headache,  with  sense  of 
weight  and  lowness  of  spirits,  and  readily  weeps.     She 
has  nausea,  indigestion,  and  often  vomits  her  food :  yet 
her  tongue  is  clean  (this  is  "  clean-tongued  "  dyspepsia). 
She  may  be  said  to  have  inflammation  of  the  stomach, 
and  her  friends  are  gravely  alarmed  about  her ;  and  every 
medical  man  of  experience  could  relate  such  cases.    She 
has  leucorrhcea  and  often  menorrhagia,  with  a  large,  heavy 
uterus.     She  cannot  hold  her  water  properly,  and  spasm 
is  readily  and  easily  produced  (the  centres  for  the  bladder 
a;id  the  reproductive  organs  lie  near  together  in  the  cord, 
and  are  therefore  a£fected  by  the  same  causeV     Beyond 
this  the  patient  has  times  of  heat,  itching,  ana  dryness  at 
the  seat  and  in   the  vagina.     In  well-marked  cases  all 
these  symptoms  are  present     The  cause  of  all  these 
linked  phenomena  is  an  irritable  ovary — when  hunted 
down.     Usually  there  is  pain  on  defecation  if  the  ovary 
lies  over  the  bowels ;  if  in  front,  pain  in  making  water. 
Usually  the  ovary  can  be  found  swollen,  and  exquisitely 
sensitive  to  the   touch.     The  sexual  act  becomes  im- 
possible from  the  contact  of  the  glans  penis  ^dth  the  ten- 
der ovary  in  many  cases.    Pressure  over  the  ovary  makes 
the  patient  feel  deadly  sick,  and  as  if  she  would  faint,  or 
fall  in  a  swoon.     Her  sensations  are  reflected  on  her 
face.     This  is  a  malady  with  distinct  and  unusually  well- 
marked  features,  yet  it  has  not  found  its  way  into  our 
text-books.     It  is  common  enough  to  well  repay  study.; 
and  in  a  well-marked  case,  when  symptom  after  symptom, 
into  the  arcana  of  her  most  private  sensations,  is  asked 
after,  the  woman  stands  as  if  in  the  presence  of  a  magi- 
cian.    Such  apparently  widely  separated  phenomena  ap- 
parently have  no  connection  with  each  other ;  yet  their 
causation  is  identical,  viz.,  a  troublesome  ovary.     Waves 
of  nerve-irritation  set  up  in  the  ovary  travel  along  difier- 
ent  nerve-fibres,  and  find  varied  terminations.     In  one 
case  they  set  up  forcible  contractions  in  the  stomach,  in 
another  they  are  felt  in  the  terminal  fibres  of  the  inter- ' 
costal  nerves  as  gusts  of  neuralgic  pain.     In  all  they 
keep  the  uterus  in  a  state  of  turgescence,  and  in  most 
there  is  leucorrhcea  and  heavy  menstrual  losses.    Slowly, 
gradually,  step  b^  step,  this  Proteus  revealed  itself  to  me 
on  patient  persistent  attention  to  it     Those  to  whom  I 
have  shown  a  typical  case  never  forget  it.     Whether  an 
equally  vivid  impression  can  be  made  by  a  mere  descrip- 
tion of  the  case  is  another  matter.     It  requires  the  pa- 
tient to  be  there  to  make  it  believable !  with  her  present, 
conviction  is  unavoidable:  without  her,  it  looks — ^well, 
'Mike  a  traveller's  tale."    Such  cases  are  very  common. 
They  do  not  readily  yield  to  treatment,  but  a  blister  over 
the  ofiending  ovary,  especially  when  the  menstrual  period 
is  due,  bromides  and  laxatives,  usually  in  time  produce 
the  desired  eflect     The  most  marked  case  which  ever 
came  under  my  notice  was  that  of  a  ladv  whose  ovaries 
had  been  forced  down   on  each  side  m  fi-ont  of  her 
bladder  by  obstinate  constipation  in  youth,  and  been 


86 


THE  MEDICAL  RECORD. 


Duly  26,  m^. 


pinned  there  by  adhesions.  She  was  barren,  and  incur* 
able,  it  is  needless  to  say. 

Then  there  are  hearts  which  do  not  exactly  palpitate, 
but  beat  tiunultuously  always,  with  paroxysms  of  true 
palpitation  at  intervals  ;  much  like  the  heart  in  cases  of 
Graves'  or  Basedow's  diseases.  Like  all  disorders  of  the 
heart  these  cases  yield  but  slowly  to  treatment ;  and  my 
impression  is  strong  that  in  cardiac  neuroses  belladonna 
is  more  useful  than  digitalis.  .1  may  remark  that  the 
effect  of  belladonna  (administered  internally)  upon  the 
pupil  is  so  fitful  and  capricious  as  to  form  no  guide  to 
its  use  ;  and  still  more  its  disuse  ! 

Dryness  of  throat  and  impairment  of  vision  are  more 
to  be  relied  upon ;  still  the  drug  need  npt  be  given  up 
even  for  them. 

Then  there  is  the  condition  of  "  irritable  heart,"  first 
described  by  DaCosta,  a  mixture  of  neurosis  with  atony, 
unfitting  the  owner  of  it  for  hard  work ;  requiring  rest 
for  its  cure,  and  patience  too.  It  is  most  common  in 
my  experience  among  doctors  of  sympathetic  tempera- 
ment, hard-workers,  who  carry  some  of  their  patients' 
cares  ;  good  fellows  who  take  their  professional  cares  to 
bed  with  them — a  practice  Clifford  AUbutt  condemned. 
The  immediate  cause  of  the  oncome  is  usually  some 
extra  demand  involving  broken  rest,  and  then  the  heart 
becomes  irritable  and  unequal  to  the  demand  upon  it. 
Rest  is  an  essential  factor  in  the  treatment  of  such  cases, 
which  get  well,  but  only  very  slowly.  It  does  not  ap- 
pear, fi"om  my  experience,  that  the  irritable  heart  ever 
passes  on  to  structural  change ;  further  experience  may 
not  corroborate  this  opinion,  but  so  far  it  holds  good. 

Then  comes  the  disturbances  of  the  heart's  rhythm, 
intermittency  and  irregularity.  Irregularity  is,  as  all 
know,  connected  with  a  dilated  heart,  especially  when 
combined  with  a  mitral  lesion.  But  intermittency  may 
be  a  mere  trick,  as  when  a  hale,  old  North  Country  woman 
observed  "  the  tick  of  her  heart  had  gone  wrong."  It  is 
not  uncommon  as  a  distinct  halt  in  the  heart,  at  varying 
intervals,  sometimes  at  long  intervals,  sometimes  fre- 
quent, in  elderly  persons,  unaccompanied  by  any  evi- 
dences of  real  mischief  afoot.  At  other  times  it  is  found 
with  senile  changes,  and  as  the  muscular  wall  of  the 
heart  is  no  longer  well-fed,  so  some  defective  nutrition 
in  the  cardiac  ganglia  may  affect  the  rhythm.  When  found 
with  hard  arteries  and  a  feebly  acting  ventricle,  where  a 
number  of  the  ventricular  contractions  fail  to  produce  an 
impression  on  the  radial  pulse,  then  it  is  at  once  sugges- 
tive and  significant.  But  frequently  intermittency  is 
found  in  young  healthy  subjects,  who  feel  no  inconve- 
nience therefirom  unless  they  are  either  medical  men 
themselves,  or  have  consulted  some  one.  Diseases  of 
the  heart,  other  than  valvular  lesions,  are  so  imperfectly 
taught  in  the  usual  hospital  career,  that  most  men  have 
but  hazy  views  of  cardiac  maladies,  and  consequently  the 
doctor  falls  back  on  what  he  knows,  or  rather  guesses, 
that  there  is  something  serious,  and  he  will  not  be  caught 
napping  in  his  estimate  of  the  gravity  of  the  case.  Cases 
tejected  for  insurance,  cases  rejected  for  the  services, 
cases  where  some  one  had  applied  a  stethoscope  without 
the  requisite  knowledge  to  wield  it  wisely,  and  so  taken 
alarm  and  communicated  it  to  the  patient,  come  con- 
stantly under  my  notice ;  and  the  apprehensions  of  the 
patient  can  usuaUy  be  set  at  rest.  There  seems  no  raison 
ditre  for  this  arythmic  condition  in  many  cases. 

Then  again  there  is  the  intermittency  so  well  and  ably 
described  by  Dr.  B.  W.  Richardson,  F.R.S.,  which  dates 
firom  some  definite  time.  A  shipwreck,  some  intense 
emotion,  or  other  exciting  cause,  and  the  action  of  the 
heart  is  disturbed.  A  marked  instance  of  this  came 
under  my  notice  some  time  ago  in  the  person  of  a  Ca^ 
nadian  store-keeper,  whose  store  caught  fire  one  night, 
and  by  desperate  exertions  (personal)  he  succeeded  in 
quelling  the  conflagration.  Next  day  he  felt  his  heart 
intermit.  He  consulted  several  medical  men  at  home 
without  satisfactory  result,  so  at  last  came  over  here, 
when  I  was  able  to  send  him  away  rejoicing ;  and  some 


eighteen  months  afterward  he  called  to  say  how  very 
much  better  he  was ;  and  certainly  the  heart  had  largely 
forgotten  that  night  of  effort  and  excitement. 

A  common  form  of  intermittency  is  that  found  after 
indigestible  meals.  Here  the  old  dogma,  "irritation of 
the  gastric  fibres  of  the  vagus,"  may  be  used  to  conceal 
our  lack  of  more  precise  knowledge,  or  in  some  cases  the 
presence  of  elastic  ^  in  the  stomach,  acting  upon  •the 
heart  through  the  thin  diaphragm,  may  be  the  cause  of 
the  disturbance.  Commonly  such  disturbance  is  seen  m 
females  of  a  highly  developed  nervous  system ;  but  is  by 
no  means  confined  to  them.  It  is  met  with  in  persons 
of  firmer  tone  after  a  debauch,  or  a  period  of  watching 
with  little  sleep,  or  any  other  cause  which  may  sap  the 
energy  of  the  nervous  system.  When  such  disturbance 
is  found,  with  evidences  of  asthenia  in  the  heart,  as  the 
result  of  a  hard  spell  of  nursing,  for  instance,  time  must 
be  allowed  for  the  heart  to  regain  its  tone. 

Marked  slowness  of  the  heart's  action  is  generally  a 
congenital  or  family  affair;  but  exceeding  rapidity  of 
the  heart's  action  is  found  in  certain  cases  as  a  new  feat- 
ure in  cardiac  disorders.  Suddenly  the  heart  will  run  off 
at  the  rate  of  two  hundred  beats  a  minute,  and  keep  this 
up  for  hours,  the  attack  passing  away  as  suddenly  as  it 
came  on,  leaving  the  patient  exhausted  ;  and  no  wonder, 
for  the  heart  must  be  like  a  tetanized  muscle  with  this 
tremendous  activity.  The  explanation  of  such  cases 
seems  to  me  to  be  a  rapid  discharge  of  the  centres  of  the 
accelerator  fibres  of  the  vagus  in  the  medulla — a  species 
of  discharge  allied  to  that  of  the  motor  centres  which 
gives  epilepsy. 

Then  there  are  cases  of  arrested  action  of  the  heart 
which  may  have  varied  causal  relations.  Certainly  sup- 
pressed gout  will  produce  surprising  lack  of  energy  in 
the  heart ;  so  much  so  that  I  have  seen  a  robust  man 
confined  to  his  bed  and  feeling  as  if  he  would  faint  on 
attempting  to  rise,  the  whole  passing  away  with  an 
attack  of  gout,  and  leaving  not  a  wrack  behind  to  tell 
of  it  In  other  cases  the  effect  is  less  pronounced ;  yet 
the  83rmptoms  of  heart-failure  are  closely  simulated, 
causing  much  alarm  and  apprehension  of  fatty  degenera- 
tion ;  such  condition  also  passing  away  with  an  explosion 
of  gout 

Comparatively  sudden  failure  of  the  heart's  action  is 
not  rarely  seen  m  over-worked  men  at  the  present  day, 
and  is  a  malady  of  which  we  shall  see  more  ere  long,  in 
my  opinion.     It  may  occur  in  stalwart  men,   and  one 
marked  case  in  a  remarkably  strong  man  came  under  my 
notice  last  summer.     A  3rachting  tour  has  resulted  in  my 
seeing  no  more  of  him.     This  failure  of  the  heart's  ac- 
tion may  be  due  to  distinctly  different  causes.     Two 
illustrative  cases  will  demonstrate  this.     A  lady  of  ad- 
mirable physique  was  severely  ill-used  by  her  husband, 
and  left  him.     At  that  time  she  suffered  from  want  of 
tone  in  her  heart,  with  attacks  of  palpitation.      Soon  she 
got  all  right     But  she  was  induced  to  return  to  him  ;  he 
again  ill-used  her ;  «an  attack  of  bronchitis  confined  her 
to  the  house,  it  being  winter,  so  she  could   not  escape. 
When  she  did  the  heart  was  found  acting  feebly,  and,  in 
place  of  the  attacks  of  palpitations,  she  was   subject  to 
S3mcopal  attacks,  in  which  the  heart's  action  was  very 
feeble,  though  she  never  actually  fainted.     She  recovered 
completely  from  this  condition.     Thus  there  seemed  to 
be  exhaustion  of  the  organic  nervous  system,  as  the  cause. 
The  next  case  contrasts  with  this.     A  medical   man  of 
magnificent  ph3rsique,  and  great  prowess  as  a  swimmer, 
came  into  my  room  one  day  leaning  on  his   stick.      He 
complained  of  inability  to  exert  himself,  and^  at  times, 
of  feeling  as  if  he  would  faint  when  the  heart's  action 
was  at  once  feeble  and  slow.     The  heart   was    sound 
enough.      He   also   complained  of   pain    betwixt    his 
shoulders.     He  was  rather  surprised  when  I   suggested 
we  should  step  over  to  Dr.  Fevrier's  and  ascertain  whal 
it  was  that  was  wrong  in  the  spine.     He  decided  tha 
there  was  some  rheumatic  thickening  of  the  spinal  men 
inges,  and  advised  counter-irritation.     As  we  returned 


July  26, 1884.] 


THE  MEDICAL  RECORD. 


87 


I  explained  that  this  was  evidently  the  cause  of  his  at- 
(j^:b— that,  in  my  opinion,  they  were  due  to  some  irri- 
tatioa  acting  through  the  inhibitory  fibres  of  the  vagus. 
This  was  a  new  light  to  him  ;  but  the  consequence  has 
been  that  with  the  disappearance  of  the  spinal  symptoms 
the  heart  symptoms  have  vanished*  and  he  is  now  as  ac- 
tive and  energetic  as  ever  he  was. 

Such,  then,  is  some  account  of  a  subject  yet  very  far 
^001  clear.    As  to  valvular  affections  and  their  recog- 
nition, probably  we  have  little  more  to  learn.     As  to 
changes  in  the  muscular  wall,  whether  gross  or  histologi- 
cal, our  ideas  are  clearing.     But  about  neuroses  of  the 
licart  we  have  still  a  very  great  deal  to  learn.    'They 
are  on  the  increase  at  the  present  time,  like  all  neurosal 
maladies.    The  older  men  have  not  described  them,  in 
great  measure  owing  to  the  fact  that  they  did  not  see 
them  as  we  are  doing.     In  another  generation  they  will 
have  become  so  important  that  a  general  recognition  of 
them  is  certain.     In  the  meantime  reflex  palpitation  is 
being  clearly  established,  though  reflex  inhibition  is  a 
leccnt  step  forward.     The  effects  of  disturbance  acting 
tough  the  inhibitory  and  through  the  accelerator  fibres 
of  the  vagus  are  just  dawning  upon  us.     When  these 
maladies  can  be  described  in  the  noontide  daylight  of 
foil  knowledge,  the  writer  of  these  articles  will  be  but  a 
memory  being  rapidly  lost  in  the  bn?y  activity  of  a  future 
time. 


THE  PREVENTION  OF  SUMMER  COMPLAINT. 

By  henry  DWIGHT  CHAPIN,  A.M.,  M.D., 

ArnDTonfc  physician  to  thb  oitt-door  dkpartmbnt,  bbllbvuk  hospital 
(ouldsbn's  class). 

Ukdbr  the  general  term  "  summer  complaint "  are  com- 
prised a  number  of  different  conditions,  including  simple 
flmctional  diarrhoea,  inflammatory  diarrhoea,  dysentery, 
and  cholera  infantum,  as  they  occur  during  early  life  in  the 
heated  part  of  the  summer.  Cholera  infantum  is  rather 
a  nure  disease,  and  occurs  infrequently  in  comparison  with 
the  other  affections  just  mentioned.  The  term  is  often 
loosely  applied  to  every  form  of  infantile  diarrhoea  occur- 
ring in  summer,  but  it  should  only  be  used  when  true 
choleraic  discharges  are  present.  The  heavy  mortal- 
it?  of  the  summer  diarrhoea  of  infancy  and  the  diffi- 
cnltyof  controlling  it,  suggests  the  inquiry  whether  more 
cannot  be  done  in  the  line  of  prevention.  The  causes 
are  well  known,  but  do  we  insist  with  sufficient  stress 
upon  thehr  palliation  or  removal  ?  One  of  the  most  fre- 
quent, and  to  a  great  extent  preventable  causes,  is  im- 
proper feeding.  The  carelessness  and  indiscriminateness 
of  die  diet  allowed  to  young  children  is  a  matter  of  con- 
tmoal  surprise.  Frequently  mere  babies  are  allowed  to 
St  at  the  table  and  partake  of  the  same  food  as  adults.  I 
bare  recently  attended  a  baby,  nineteen  months  old,  who 
experienced  some  inconvenience  after  eating  huckleberry 
pie  with  the  rest  of  the  family ;  and  in  another  case  a 
mother  had  given  her  baby,  aged  fifteen  months,  a  little 
corned  beef  hash.  Although  an  unwholesome  diet  may 
wnetimes  be  apparently  taJcen  with  impunity,  there  still 
Ubws  an  impairment  of  the  digestive  power  of  the 
stomach  and  intestines  that  is  a  continual  predisposing 
Cfflse  of  diarrhoea.  Nor  is  it  easy  to  understand  how 
Ais  could  be  otherwise.  The  undigestible  contents  of 
fte  stomach  and  intestines  speedily  undergo  fermentative 
^ges  that  eventuate  in  the  formation  of  butyric  and 
^adds.  These  irritating  acids  frequently  stimulate 
(he  intestinal  follicles  to  excessive  secretion  and  increase 
tfc  peristaltic  movements.  The  marked  acid  odor  of  the 
iwrited  matters  and  fecal  discharges,  and  the  accompa- 
^fing  excoriation  of  the  buttocks,  are  frequently  evidences 
«f  tfis  fermentative  process.  Too  early  weaning  of  in- 
iwsj  especially  just  before,  or  during  the  hot  months,  is 
ifrahfol  source  of  trouble,  and  should  always  be  avoided, 
hi  order  to  show  the  dangers  of  summer  diarrhoea  to 
«ificially.fed  babies,  the  Bureau  d'Hygidne  of  the  city 


of  Rheims,  France,  in  July,  1882,  made  a  slight  change 
in  the  form  of  death-report  required  in  cases  of  infantUe 
diarrhoea.  Children  dying  from  this  disease  were  divided 
into  two  classes — ^those  nourished  by  mother's  milk,  and 
those  brought  up  by  hand.  From  July  ist  to  December 
31st,  thirty-one  infants  nourished  at  the  breast  and  two 
hundred  and  seventy-two  brought  up  on  the  bottle  died  of 
infantile  diarrhoea.  While  these  figures  show  a  larger 
relative  mortality  in  hand-fed  babies  than  we  are  accus- 
tomed to  see  here,  they  nevertheless  enforce  an  impor- 
tant fact.  And  yet  babies  are  often  removed  fi-om  the 
breast  at  this  season  for  the  most  trifling  reasons.  Even 
serious  objections  to  nursing  must  be  carefully  considered 
before  taking  the  risks  of  an  exclusively  artificial  diet 
in  hot  weather.  Despite  menstruation,  and  even  of 
pregnancy,  it  is  often  better  for  the  infant  to  continue 
nursing  until  the  weather  becomes  cooler.  The  thirst 
naturally  produced  by  the  heat  causes  the  baby  to  wish 
to  nurse  or  take  the  bottle  very  frequently,  and  as  a  re- 
sult colic  and  indigestion  are  soon  induced,  which  often 
eventuate  in  diarrhoea.  The  cause  of  this  is  evident. 
There  is  a  continual  rapid  evaporation  from  the  skin,  and 
as  a  result  of  this  flmid  loss  the  watery  parts  of  the  food 
are  quickly  absorbed  to  make  up  the  deficiency,  leaving 
the  thickened  solid  part  to  ferment  and  cause  irritation. 
This  cause  of  diarrhoea  can  be  removed  by  giving  mUk 
or  other  nourishment  only  at  suitable  intervals,  but  allow- 
ing the  baby  to  drink  frequently  of  water,  administered 
in  small  quantities  at  a  time.  The  avidity  with  which  it 
drinks  will  confirm  the  indication  for  its  administration. 
Thin  barley-water  often  agrees  better  with  the  stomach 
in  hot  weather,  except  in  very  young  babies.  Restricted 
nursing  and  a  more  liberal  supply  of  water  would  pre- 
vent many  attacks  of  diarrhoea  in  infancy. 

It  will  be  impossible  to  cite  all  the  common  errors  in 
infantile  diet  that  help  to  form  such  a  heavy  mortality 
during  the  summer  months.  Every  physician  can  do 
much  in  individual  cases  to  lessen  this  mortality  by  find- 
ing out  and  preventing  these  errors.  I  think  that 
mothers,  especially  those  living  in  tenement-houses, 
should  receive  minute  and  explicit  directions  as  to  the 
diet  of  their  babies  at  different  ages,  and  any  society  that 
will  attempt  such  a  work  can  do  vastly  more  good  than 
in  trying  to  teach  ladies  how  to  support  a  mangled  limb 
until  the  doctor  arrives. 

The  intense  and  all-pervading  heat  of  the  summer 
months  forms  a  factor  in  infantile  diarrhoea  that  is  not 
so  easy  to  eliminate.  And  yet  much  can  be  done  even 
here  in  the  way  of  prevention.  Heat  acts  directly  and 
indirectly  in  causing  the  mortality  due  to  summer  diar- 
rhoea. It  acts  directly  on  young  children  by  depressing 
and  rendering  more  susceptible  their  nervous  energy, 
by  enfeebling  the  digestive  organs,  and  by  increasing  but 
weakening  the  action  of  the  heart.  The  indirect  effects 
of  heat  are  caused  by  fermentative  changes  in  the  food 
of  infants  and  in  surrounding  domestic  and  civic  filth. 
The  direct  connection  between  decaying  refuse  matter 
and  summer  complaint  is  shown  by  the  fact  that  where- 
ever  the  filth  is  greatest  the  death-rate  from  this  cause 
is  highest.  There  is  a  plain  indication  here  for  pre- 
ventive treatment.  The  physician  must  insist  upon  the 
most  scrupulous  personal  and  domiciliary  cleanliness 
during  the  hot  months,  while  boards  of  health  look  after 
the  condition  of  sewers,  streets,  and  drains.  Fermenta- 
tion changes  in  milk  can  be  largely  obviated  by  boiling 
it  when  fresh  to  destroy  all  germs,  and  then  adding  a 
little  alkali. 

The  direct  effect  of  heat,  aside  from  any  increased 
foulness  of  the  air  that  it  induces,  is  an  interesting 
point  to  consider.  I  have  prepared  the  following  table 
from  statistics  derived  from  the  Board  of  Health.  It 
consists  of  a  comparison  of  the  death-rates  fi'om  diar- 
rhoeal  diseases  between  two  winter  months  and  two 
summer  months,  together  with  the  mean  temperature  of 
each  month.  Under  diarrhoeal  diseases  are  included 
simple  diarrhoea,  dysentery,  entero-colitis,  cholera  infan- 


88 


THE  MEDICAL  RECORD. 


[July  26, 1884. 


tuna,  cholera  morbus,  Asiatic  cholera,  diarrhoeal  gastro- 
enteritis, and  diarrhoeal  enteritis. 

Deaths  from  Diarrheal  Diseases  in  New  York. 
1882. 

JaK.       Feb.         July.        Augusts 

Mean  temp.,  Fahr 28.77"   35-21''     75.79*     7342" 

Deaths  under  five  years 34        32  1,533        817  \ 

Deaths  over  five  years 14        15  131         149 

1883. 

Mean  temp. ,  Fahr 25. 1 8**   30. 24°     74.46"     70.40' 

Deaths  under  five  years. 32        32        Ii355  507 

Deaths  over  five  years 14        16  125  1 16 

A  glance  at  this  table  will  show  the  tremendous  in- 
crease in  the  death-rate  under  the  age  of  five  years  in 
coniparison  with  that  occurring  above  that  a^e,  the  dif- 
ference in  winter  being  about  double,  while  in  summer 
it  is  vastly  higher  than  that  proportion.  It  also  shows 
that  the  month  having  the  highest  mean  temperature, 
July,  has  much  the  highest  death-rate  in  children  under 
five  years,  while  in  cases  above  five  years  of  age  there  is 
no  appreciable  diflference  between  July  and  Augugt.  In 
1882  and  1883  there  was  an  increase  of  the  mean  tem- 
perature of  July  over  August  of  from  2.37°  to  4.06° 
Fahr.  The  difference  in  heat  represented  by  these  few 
degrees  doubled  the  death-rate  in  children  under  five 
^ears.  As  tenement-houses  and  streets  are  no  cleaner 
in  August  than  in  July,  and  as  there  is  quite  sufficient 
heat  and  moisture  during  August  to  cause  free  fermenta- 
tion in  any  filth,  it  is  evident  that  the  increased  infantile 
mortality  during  July  is  due  to  a  slight  increase  in  the 
heat,  as  the  other  elements  causing  it  are  about  the 
same.  It  is  an  impressive  commentary  on  the  inability 
of  infants  to  stand  a  high  temperature  well,  that  in 
1882  an  increase  of  2°  in  temperature  was  sufficient  to 
raise  the  death-rate  by  just  716  young  children  in  one 
month.  It  is  also  seen  by  referring  to  the  table  that  the 
mean  temperature  of  July,  1882,  was  1.33°  higher  than 
that  of  July,  1883,  and  there  were  178  more  deaths  in 
children  under  five  years  in  the  former  month.  One 
explanation  of  the  much  higher  death-rate  of  July  over 
August  may  be  that  most  of  the  weak,  bottle-fed  babies 
die  during  the  first  heated  period  ;  but  this  can  be  offset 
by  the  fact  that  infants  a  little  stronger  and  having  more 
resisting  power  finally  succumb  in  August,  exhausted  by 
the  long-continued  heat.  I  think  that  sufficient  stress 
has  not  been  devoted  to  the  injurious  effects  of  heat 
itself  upon  young  children  by  writers  on  this  subject, 
and  that  relatively  too  preponderating  an  influence  has 
been  given  to  impure  air.  The  disastrous  effects  are 
due  to  such  an  intimate  combination  of  these  two  agents 
that  it  is  somewhat  difficult  to  estimate  their  separate 
influences.  But  while  it  is  easy  to  understand  the  in- 
jurious effects  of  breathing  a  foul  atmosphere,  and  its 
depreciating  consequences  are  constantly  seen,  yet  the 
system,  in  a  sense,  gets  accustomed  to  impurity,  and 
throws  it  off  more  or  less  readily.  Young  children  live 
for  months  shut  up  in  filthy  apartments  without  dying, 
and  even  seeming  to  enjoy  tolerable  health. 

Of  course  they  grow  scrofulous  and  readily  fall  victims 
to  disease ;  but,  after  all,  the  organism  seems  to  estab- 
lish a  sort  of  toleration  for  filth,  just  as  for  arsenic  and 
many  other  poisons.  Continuous  and  intense  heat  does 
not  seem  to  allow  of  any  such  escape.  It  is  difiicult  to 
explain  exactly  the  reason  that  excessive  heat  produces 
such  fatal  results  in  early  life.  It  has  been  affirmed  ^at, 
in  accordance  with  the  physiological  law  of  vicarious 
functional  action,  the  over-stimulation  of  ^reat  heat  in- 
terferes with  the  secretive  powers  of  the  skin,  and  hence 
the  mucous  membrane  is  excited  to  a  morbid  activity.  If 
such  a  relation  exists,  it  is  probably  more  intimate  in 
children  than  in  adults.  Again,  the  depressing  effect  of 
great  heat  upon  the  nervous  system  is  familiar  to  every 
one.     In  infants,  as  the  vegetative  processes  are  most 


active,  the  great  sympathetic  ganglia  presiding  over  them 
hold  a  very  prominent  position  m  their  nervous  econ- 
omy, and  are  hence  markedly  affected  by  depressing 
agents,  as  heat.     Impaired  innervation  of  the  stomach 
and  intestines  follows,  which  results  in  a  diarrhoea  upon 
the  slightest  irritation.     Physiological  processes,  under 
the  especial  control  of  the  sympathetic  nerves,  require  a 
longer  time  to  be  influenced  by  perturbing  causes  than 
those  controlled  by  the  cerebro-spinal  system.    Accord- 
ing  to   Dalton,   inflammation   of  any  internal  organ  is 
rarely  established  until  twelve  or  twenty-four  hours  after 
the  exciting  cause.     The  increased  mortality  in  young 
children  does  not  usually  commence  until  a  day  or  so 
after  the  great  heat  begins,  and  continues  a  like  period 
after  the  cessation  of  the  heated  term.     While  there  may 
be  some  uncertainty  as  to  the  exact  way  in  which  heat 
acts,  its  unmistakable  effects  lead  us  to  ask  whether  even 
here  some  preventive  measures  may  not  be  of  avail.  The 
free  use  of  the  bath,  which  is  apt  to  be  too  much  neg- 
lected, especially  among  the  poorer  classes,  will  do  much 
to  obviate  the  depressing  effects  of  excessive  heat 

In  an  exhaustive  monograph,  "  On  the  Effects  of  High 
Temperature  upon  the  Public  Health,"  Professor  Stephen 
Smith  has  thoroughly  discussed  the  subject  of  warm  and 
cold  bathing  in  this  connection.    The  cold  bath  is  gen- 
erally  used  for  cooling  the  body ;  as  it  quickly  abstracts 
heat  from  the  surface  by  conduction,  there  follows  a  sud- 
den reduction  of  the  temperature.     By  constringing  the 
vessels  of  the  skin,  however,  the  blood  is  forced  to  the 
internal  organs,  which  are  thereby  stimulated  to  func- 
tional activity,  and  hence  as  a  secondary  effect  heat  is 
produced.     At   the   same  time   the   mass  of  blood,  by 
leaving  the  surface,  ceases  to  remain  in  contact  with  the 
cool  medium.     After  this  temporary  rise,  the  tempera- 
ture soon  falls  to  normal,  and  equilibrium  is  restored. 
The  effect  of  a   cold  bath  upon  the  l)ody  temperature 
would  be  thus  represented  by  a  curve  indicating  first  a 
fall,  next  a  rise  above  normal,  and  finally  a  return  to  the 
average.     When  a  warm  bath  is  used  heat  is  communi- 
cated to  the  body  by  conduction,  and  the  temperature  is 
elevated.     At  the  same  time,  by  relaxation  of  the  blood- 
vessels and  skin,  the  cutaneous  secretions  are  increased, 
the  blood  is  withdrawn  from  the  viscera,  and  a  cooling 
process  takes  place  by  means  of  active  evaporation.     In 
a  warm  bath,  therefore,  the  curve  first  rises,  but  next 
falls  below  normal,  and  finally  reaches  the  average.     An 
increased  coolness  follows  its  administration,    while  a 
warm  sensation  often  follows  a  cold  bath  on  a  very  hot 
day.     Wunderlich  states  that  in  tropical  countries,  and 
very  hot  seasons,  no  means  of  cooling  is  so  lasting  as  a 
bath  or  douche  of  very  warm  water.     The  bad  effects  of 
great  heat  upon  young  children  can,  then,  to  a  certain 
extent,  be  obviated  bjr  eiving  them  a  suitable  bath  every 
afternoon.    If  the  cmldren  are  old  enough,  place  them 
in  a  tepid  or  warm  bath,  and  let  them  play  there  for  an 
hour.     The  skin   will  thus  be  kept  active,   the  blood 
cooled  by  being  brought  to  the  surface,  and  evap>oration 
continue  for  some  time.     Of  course  the  water  should  not 
be  used  so  warm  as  to  produce  relaxation.     In  the  case 
of  babies  too  young  for  the  bath,  frequent  spongings  of 
the  whole  body  with  lukewarm  water  will  fulfil  the  same 
indication.     A  little  vinegar  or  alcohol  may  be  added  to 
the  water  to  aid  evaporation.     If  an  infant    begins  to 
droop,  it  is  well  to  give  whiskey  or  brandy,  in   doses  of 
from  two  to  three  drops  for  every  month  of  its  age  up  to 
a  year,  and  repeated  several  times  a  day.     Finally,  in- 
fants should  be  taken  daily,  in  the  early  morning  or  even- 
ing, to  parks,  or  on  a  ferry-boat,  where  they  can  get 
pure  air.     If  well  babies  could  be  thus  daily  refreshed 
they  would  be  much  less  likely  to  fall  victims  to  summei 
complaint.     In  the  tenement-house  districts  of  this  city 
they  are  often  confined  to  the  house  for  days.     The 
slightest  manifestation  of  diarrhoea  in  children  during  the 
hot  months  should  be  speedily  arrested.     Many  mothen 
have  an  idea  that  a  diarrhoea  occurring  during  teething 
should  not  be  quickly  checked.     Very  frequently  babiei 


July  26, 1884.] 


THE  MEDICAL  RECORD. 


89 


are  brought  during  these  hot  days  to  my  clinic  at  Belle- 
vDe  half  dead,  or  d3ang,  from  summer  diarrhoea  that  has 
been  allowed  to  run  on  a  week  unchecked,  because  it 
occnned  during  dentition.  Many  deaths  occur  annually 
from  this  mischievous  notion  on  the  part  of  mothers. 

Just  now,  as  we  are  beginning  to  hear  much  of  chol- 
era, adults  will  also  be  warned  against  allowing  a  diar- 
rhoea to  continue  unchecked.  It  is  peculiar  to  notice  in 
this  connection  that  while  summer  diarrhoea  attacks  bv 
preference  young  childrexi,  Asiatic  cholera,  to  which  it 
bears  some  resemblance  in  many  of  its  symptoms  and 
pathological  changes,  does  not  attack,  as  a  rule,  the  pe- 
riod of  childhood. 

A  CONTRIBUTION  TO  THE  LITERATURE  OF 
PLACENTA  PREVIA,  WITH  A  HISTORY  OF 
EIGHT  CASES. 

By  E.  p.  CHRISTIAN,  A.M.,  M.D., 

WYAMSOTTBy  WIS. 

The  comparative  rarity  of  this  accident  of  parturition 
with  others  of  the  dangerous  complications,  and  the  dis- 
mal records  of  its  literature,  are  reasons  sufficient  for  any 
physician  having  had  any  considerable  recorded  expe- 
rience with  such  cases  for  giving  their  histories  and  re- 
sults to  the  profession.  Even  though  the  results  of  one's 
experience  may  not  differ  from  the  average,  and  he  may 
have  no  new  suggestions  to  offer  as  regards  their  manage- 
ment, yet  the  recorded  histories  of  their  individual 
peculiarities,  indications^  and  results  serve  to  increase 
the  rather  meagre  statistics  on  which,  as  yet,  theories 
and  conclusions  are  based,  and  will  help  to  the  increase 
of  that  larger  mass  of  facts  upon  which  more  reliable  con- 
dosions  majr  be  built  in  the  future.  Fortunate  for  the 
parturients  is  it  that  the  danger  of  exposure  to  this  ac- 
ddeiit  is  so  small,  but  unfortunate  for  obstetric  science 
that  its  comparative  rarity  affords  any  one  individual  so 
limited  experience  from  which  to  generalize.  This 
infrequency,  I  suppose,  arises  not  merely  from  its  being  an 
onnatural  condition,  the  sequence  of  conception  occur- 
ring in  an  abnormal  state  or  condition  of  the  uterus,  or 
from  accidental  violence  to  the  mother  disturbing  the 
ovuin  in  its  earliest  period  of  intra-uterine  existence. 
Ifthu  were  all,  we  might  expect  the  accident  of  placenta 
pneria  to  be  of  even  much  more  frequent  occurrence 
than  it  is.  But  I  suppose  it  to  be  in  that  wonderful  pro- 
vision against  the  future  danger  to  the  mother,  of  child- 
birth at  term,  in  the  fact  of  the  natural  tendency  of  this 
condition  to  terminate  in  an  early  abortion.  This  con- 
dition I  believe  to  be  the  cause  of  very  many  early 
abortions,  often  sufficient  of  itself,  oftener  perhaps  re- 
quiring only  the  slightest  accidental  violence  superadded 
to  induce  the  abortive  process,  and  which  latter  accident 
invariably  is  alleged  as  the  cause.  That  the  condition 
of  placenta  praevia  has  existed  in  numerous  early  abor- 
tions of  which  I  have  had  the  care,  I  have  certain  and 
tadobitable  proof  from  observation ;  and  when  the  patient, 
other  by  sufferance  of  nature  or  the  aid  of  medical  art, 
kas  advanced  to  later  stages  of  pregnancy,  the  tendency 
to  miscarriage  still  continues,  as  is  evidenced  by  the  pre- 
maturity of  so  many  labors  after  the  stage  of  viability  of 
tile  child  has  been  reached ;  and  when  the  tendency  to 
tarly  abortion  has  been  surmounted,  the  woman  has  es- 
caped that  accident  only  to  become  exposed  to  increas- 
ing dangers  at  parturition  in  proportion  to  the  stage  of 
advancement  toward  full  term.  And  as  this  condition — 
fbcenta  praevia — ^is  a  frequent  cause  of  abortion,  so  is  the 
reverse  equally  true,  that  frequent  abortions  are  a  cause 
^placenta  praevia,  or  of  the  condition  of  the  uterus 
1^  predisposes  to  the  accident.  I  suppose  there  is 
>o  more  frequent  cause  of  a  subinvoluted  and  enlarged 
ttd  patulous  ntems  than  frequent  abortions.  Such  an 
■tons,  with  its  unopposed  walls,  fails  to  retain  the  ovum 
ititi  fundus  on  its  arrival  and  entrance  from  the  Fallopian 
^^  and  it  falls  by  gravity  or  is  washed  down  by  men- 
*tel  secretions,  or  is  displaced  by  ritght  jars  or  other 


violence,  and  reaches  the  lower  portion  of  the  uterus, 
there  to  form  its  attachment. 

I  have  stated  that  the  literature  of  placenta  praevia 
presents  but  dismal  records,  which  fact  is  sufficiently  well 
understood  by  the  profession  in  a  general  way,  but  only 
realized  in  its  full  significance  by  one's  individual  expe- 
rience. During  the  past  year  there  have  been  a  number 
of  contributions  to  the  literature  of  the  subject  in  the 
medical  journals,  and  which  exhibit  better  results,  as  far 
at  least  as  fatality  to  the  mother  is  concerned,  than 
we  can  be  justified  in  drawing  from  the  statistics  of  text- 
book authorities.  Perhaps  this  ma^  be  in  some  measure 
because  the  more  favorable  exhibits  are  the  most  likely 
to  reach  the  light  of  publication.  I  shall  make  reference 
to  such  of  this  recent  literature  as  has  come  under  my 
notice,  both  for  the  statistical  results,  for  comparison's 
sake,  and  also  by  reference  to  some  of  the  conclusions. 

As  to  the  general  average  of  fatality  in  placenta  praevia, 
Churchill  states  (edition  of  i860) :  "  In  placenta  praevia, 
under  ordinary  management,  one  in  three,  or  thereabouts, 
of  the  mothers  are  lost,  and  more  than  half  of  the  chil- 
dren. **  This  statement  has  been  criticised  as  exaggerated. 
If  it  represents  that  of  all  cases  occurring,  the  unpub- 
lished as  well  as  the  published,  it  is  probably  not  an  ex- 
SLggerated  statement.  In  fact,  as  to  the  fatality  to  chil- 
dren it  probably  does  not  represent  that  sufficiently  high 
even  under  skilful  management. 

T.  Curtis  Smith,  M.D.,  of  Aurora,  Ind.,  in  a  paper 
published  in  ne  Medical  and  Surgical  Reporter  of 
Philadelphia,  July  14,  1883,  states  that  Dr.  K  W.  King, 
of  New  Albany,  Ind.,  has  gathered  two  hundred  and  fifty 
cases  occurring  in  the  practice  of  physicians  of  that  State. 
"  Of  that  number  there  was  a  loss  of  fifty-five  mothers, 
or  twenty-two  and  one-half  per  cent.  The  mortality 
among  children  was  one  hundred  and  thirty-five,  or 
over  fifty-seven  per  cent''  These  figures  would  give 
a  loss  of  mothers  of  i  in  4.4.  ^'  Of  three  hundred 
and  thirty-two  cases  collected  by  Schwartz,  there  was 
one  death  in  3.86."  <*  Simpson  states  a  mortality  of 
I  in  3.6."  "Trask  (Prize  Essay)  i  in  3.95."  Dr.  Smith, 
author  of  the  paper,  ^ves  a  history  of  three  cases  in 
his  practice,  one  of  which  was  of  central  implantation — 
delivery  by  version.  All  the  mothers  were  saved,  and 
two  of  the  children.  Dr.  Smith  remarks  :  '<  It  is  an  un- 
happy fact  that  a  larger  proportion  of  cases  of  placenta 
praevia  give  mal-presentations  than  where  the  placenta 
is  otherwise  normally  attached,  and  hence  version  is 
often  a  necessary  procedure  and  often  causes  a  fatal 
issue." 

In  Dr.  Simpson's  tables  a  large  number,  twenty-three 
in  ninety-one,  or  about  twenty-five  per  cent ,  were  of  mal- 
presentations,  as  of  shoulder,  arm  or  hand,  and  head. 
This  frict,  besides  its  bearing  on  the  rate  of  fatality,  has 
another  interest  to  us  in  its  bearing,  or  the  hint  it  gives  us 
of  the  causes  of  this  accident — ^placenta  praevia — to  which 
we  have  made  reference,  and  shall  do  so  again  further 
on. 

D.  C.  Davis,  M.D.,  of  Columbus,  Wis.,  read  a  paper 
on  this  subject  before  the  Wisconsin  State  Medical 
Society,  and  published  in  the  "Journal  of  the  American 
Medical  Association,  September  15,  1883,"  in  which  he 
records  the  exceptional  experience  of  having  met  with 
seventeen  cases  of  placenta  praevia  in  sixteen  years  of 
practice.  He  had  saved  all  the  mothers,  and  saved  but 
one  child.  He  gives  a  brief  history  of  two  cases  in 
succession  of  centndly  implanted  placenta  terminated  by 
perforation  and  turning,  and  formulates  the  following 
conclusion,  emphasized  in  italics :  "  TTuil  without  doubt 
rapid  perforation^  version^  and  delivery  ofers  the  easiest^ 
speediest,  and  sqfest  chance  of  life  to  the  child  and  safety 
to  the  mother  of  any  manner  or  mode  of  management  here^ 
tofore  culvocated  and  known  to  me** 

He  also  makes  the  following  statement  of  a  fact  re- 
marked also  by  others,  and  so  markedly  corroborated  by 
my  own  experience,  and  a  truth  of  such  import  and 
relevancy,  that  I  consider  it  worthy  of  special  emphasis : 


90 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


"Another  fact  in  favor  of  this  mode  of  procedure  is  the 
dilatability  of  the  os  and  cervix  in  cases  of  placenta 
praevia  hemorrhage,  for  I  know  whereof  I  spes^  when 
I  aver  that  the  uterus,  from  loss  of  blood  in  these  cases, 
is  rendered  more  passive  and  dilatable,  and  consequently 
version  is  more  easy  of  accomplishment  than  in  any 
other  mal-presentatibn/' 

Dr.  J.  K.  Bartlett,  Chairman  of  Section  of  Obstetrics  and 
Diseases  of  Women,  in  his  report  at  the  meeting  of  the 
American  Medical  Association  in  1883,  has  the  following 
on  this  subject :  "  The  report  of  Mr.  Hofiman,  of  Berlin, 
on  this  subject  deserves  notice  from  its  unusually  favorable 
results.  He  cites  forty-six  cases.  Of  these,  three  were  so 
near  death  when  seen  that  there  was  no  opportunity  for 
treatment.  Of  the  remaining  forty-three,  six  were  treated 
by  the  waiting  method  and  the  tampon.  In  the  other 
thirty-seven  no  tampon  was  used.  Of  the  six  treated  by 
tampon  at  an  earlier  date,  one  died,  two  had  a  long  and 
severe  illness,  and  four  children  were  dead.  Of  the 
thirty-seven  treated  differently  one  mother  only  died, 
and  she  had  been  treated  by  tampon  for  twenty-four 
hours,  and  the  placenta  was  offensive  when  delivered." 
(No  statement  of  results  to  children.) 

With  this  cursory  review  of  some  of  the  recent  litera- 
ture of  placenta  praevia  as  an  introduction,  I  will  now 
give  briefly  the  histories  of  my  own  cases,  eight  in  all. 

Case    I. — Mrs.   C y   American;-  seventh    labor. 

Patient  weakly  and  delicate,  but  obliged  to  do  her  own 
housework.  The  subject  of  several  abortions.  No  com- 
plications in  previous  labors  at  term.  Commenced  flaw- 
ing at  about  seven  and  one-half  months ;  controlled  each 
time  by  tampon.  Labor  was  ushered  in  and  accom- 
panied by  fearful  and  exhaustive  flooding.  Placenta  im- 
planted centrally  over  the  os,  and  was  expelled  in  ad- 
vance of  the  child's  head,  wUch  was  immediately  after 
delivered  by  forceps.  The  child  presented  evidences  of 
having  been  dead  for  probably  some  days  previous,  by 
reason  of  commencing  decomposition.  Woman  had  a 
very  slow  and  tedious  recovery.  This,  my  first  case,  and 
at  a  very  early  period  of  my  practice,  was  the  worst  case 
I  have  ever  had.  With  my  present  knowjedge  and  experi- 
ence, in  a  similar  case,  I  should  perforate,  turn,  and  de- 
liver. This,  as  was  shown  after  delivery,  would  have 
made  no  difierence  as  far  as  the  child  was  concerned, 
but  would  have  terminated  the  labor  more  rapidly  and 
have  saved  the  woman  considerable  blood. 

Cass  II. — Mrs.  S ,  English ;  ninth  labor.     Heavy 

flowing  came  on  at  2  p.m.  ;  easily  controlled,  and  labor 
pains  set  in  at  8  p.m.  Examination  showed  marginal 
attachment  of  placenta,  and  head  already  descended  so 
as  to  check  the  hemorrhage.  The  child  was  speedily 
born,  the  placenta  coming  away  immediately  after.  No 
interference  was  necessary  to  hasten  labor,  and  the 
woman  quickly  recovered.     The  child  was  dead. 

Cass  III. — Mrs.  H ,  Irish;  first  labor.     Flowing 

at  frequent  intervals  for  past  month.  Had  pains  since 
morning,  with  hemorrhage.  I  saw  her  for  first  time  at 
9  P.M.,  when  she  was  flooding.  Found  marginal  attach- 
ment of  placenta.  Os  only  dilated  to  admit  two  fingers, 
but  soft  and  easily  dilatable,  notwithstanding  this  was  a 
primipara.  There  had  been  great  losses  of  blood,  and 
of  course  great  prostration  and  relaxation.  I  dilated 
rapidly  with  my  hand,  turned  readily,  and  delivered 
speedily.  Child  dead  and  decomposing.  Mother  had 
felt  no  life  for  five  days  previous.  Mother  [recovered 
quickly. 

Case  IV. — Canadian  French ;  sixth  labor.  I  was 
called  to  the  patient  on  account  of  dangerous  flooding. 
Examination  showed  the  os  already  well  dilated,  with 
head  presenting,  and  marginal  attachment  of  placenta ; 
pains  feeble  and  inert,  as  usual  after  excessive  loss  of 
blood,  and  insuflicient  to  press  the  head  down  with  suf- 
ficient force  to  check  the  hemorrhage,  I  applied  the 
forceps,  bringing  down  the  head,  which  immediately 
checked  the  flow,  and  readily  and  easily  delivered  a  large 
and  living  boy.     A  slight  incident  in  this  case  illustrates 


how,  without  great  carefuhiess  in  the  application  of  the 
blades  in  such  cases,  a  serious  accident  might  occur,  and 
one  in  regard  to  which  I  do  not  recollect  to  have  seen 
any  caution,  perhaps  because  writers  usually  advise 
against  the  use  of  the  forceps  in  placenta  prsevia.  Hav- 
ing applied  the  blades,  I  commenced  with  a  gende  trac- 
tion, upon  which  the  woman  screamed  out  that  I  was 
tearing  her.  I  unlocked  the  blades  and  carefully  re- 
applied, with  no  further  complaint  on  traction.  I  had 
doubtless  grasped  a  part  of  the  membrane  of  the  pla^ 
centa  between  the  blade  and  head.  The  woman  made 
a  speedy  recovery. 

Cass  V, — Mrs.  G.  B— ,  Canadian  French;  tenth 
labor.  I  was  called  to  this  patient  some  distance  b 
the  country,  on  account  of  dangerous  flooding,  the 
woman  being  in  eighth  month  of  pregnancy  and  not  yet 
expecting  labor.  Examination  showed  os  uteri  soft  and 
dilatable,  but  as  yet  dilated  only  to  admit  finger,  and 
central  implantation  of  placenta ;  very  feeble  pains,  as 
usual  after  excessive  hemorrhage,  and  woman  danger- 
ously prostrated  for  so  unadvanced  a  stage  of  the  labor. 
I  commenced  giving  er^ot  to  promote  contraction,  as- 
sisted with  digital  dilatation,  and,  as  soon  as  practicable, 
separation  of  placental  attachment  on  one  side  until  the 
bag  of  waters  could  be  felt,  which  was  ruptured.  This, 
with  the  increasing  ergotic  contractions,  brought  the 
head  against  the  bleeding  surface,  checking  the  hemor- 
rhage. Labor  progressed  favorably,  and  die  child  was 
bom,  the  placenta  having  become  totally  detached  by 
the  advancing  head,  and  coming  before  it  The  child 
was  dead. 

Cask  VI. — Mrs.   J ,   Canadian;    seventh  labor. 

Threatened  abortion  at  fourth  month,  with  hemorrhage ; 
agaui  at  fifth  month  in  increased  quantity  ;  recurring  at- 
tacks in  increasing  frequency  up  to  the  seventh  month, 
when  indications  of  labor  set  in  with  such  terrific  losses 
of  blood  that  on  my  arrival  I  considered  it  necessary  to 
terminate  labor  as  speedily  as  possible  to  save  the 
woman's  life.  The  safety  of  the  child,  under  the  cir- 
cumstances, was  considered  a  small  matter,  especially  as 
the  woman  was  only  at  the  seventh  month,  and  I  con- 
sidered that  the  previous  long-continued  hemorrhages 
had  in  all  probability  compromised  its  chances  of  hfe. 
At  any  rate,  it  was  necessary  that  assistance  should  be 
given  promptly  to  the  mother  or  she  would  be  lost 
Examination  showed  central  implantation  ;  os  dilated  to 
some  extent;  easily  dilatable  and  soft;  pains  inert 
Gave  ergot  liberally ;  accomplished  rapid  manual  dila- 
tation ;  detached  placenta ;  performed  version,  and 
delivered  a  dead  boy.  Woman  recovered,  but  required 
time  to  recuperate  from  her  excessive  prostration. 

Case  VII.— Mrs.  C.  S ,  German ;  fifth  labor.  Pos- 
terior marginal  implantation  of  placenta,  with  presentation 
of  left  arm  and  prolapsed  funis ;  patient  attended  by  a  mid- 
wife, who  sent  for  me  on  account  of  the  mal-presentation 
and  severe  hemorrhage  since  commencement  of  labor,, 
which  was  at  full  term.  Os  sufficiently  dilated  on  my 
arrival  for  immediate  assistance,  which  I  proceeded  to- 
render  by  turning  the  child  and  delivering  by  the  feet, 
and  which  was  readily  accomplished,  and  the  woman  de- 
livered of  a  dead  boy.    Woman  speedily  recovered. 

Case  VIII. — Mrs.  G ,  German;  mother  of  two 

healthy  children,  born  at  full  term,  by  first  husband,  and 
of  numerous  abortions  by  her  second  The  case  was 
one  of  miscarriage  at  sixth  month,  and  unaccompanied 
or  preceded  by  henoorrhage  until  after  perforation  of  pla- 
centa, and  then  comparatively  insignificant.  The  case 
was  peculiar  and  unique.  Threatened  abortion,  as  usual^ 
at  about  the  third  month,  with  discharge  of  water,  but 
without  hemorrhage.  Water  had  continued  dribbling 
away  ever  since.  Labor  came  on  and  progressed  very 
slowly  on  account  of  inefficiency  of  pains.  The  os  hav- 
ing after  many  hoiu^  become  well  dilated,  I  concluded 
to  rupture  what,  from  the  undeveloped  condition  of  pla- 
centa at  that  stage  of  gestation,  firom  its  being  free  from 
attachment  in  the  neighborhood  of  the  os  and  jdelding 


July  36,  1884.] 


THE  MEDICAL  RECORD. 


91 


before  the  pressure  of  the  finger,  and  from  the  absence 
of  bemonfaage,  I  did  not  suspect  to  be  the  placenta,  but 
the  amniotic  bag,  for  the  purpose  of  engaging  the  foetus 
in  the  mouth  of  uterus,  and  increasing  the  force  of  the 
inert  pains.    I  found  this  unusually  thick,  and  more  diffi- 
cult of  penetration  than  usual,  and  its  accomplishment 
was  followed  by  a  discharge  of  blood  for  the  first  time. 
A  leg  was  found  presenting  and  brought  down,  and  the 
body  engaging  the  hemorrhage  ceased  and  child  was 
soon  bom.     It  was  felt  to  move  during  extraction,  but 
showed  no  indications  of  life  after  it  was  bom,  probably 
owing  to  some  delay  with  the  head     Attention  was  now 
given  to  extraction  of  the  placenta,  which  was  found 
covering  the  os  and  firmly  attached  away  from  its  mar- 
gins.   So  firmly  adherent  was  it,  and  so  sensitive  the  os, 
and  80  painful  were  manipulations,  that  it  was  necessary 
to  pat  the  patient  under  chloroform  for  that  purpose. 
Exunioation  of  the  placenta  showed  the  rent  near  one 
border,  through  which  the  child  had  been  extracted. 
The  separation  of  the  placenta,  in  this  case,  I  suppose  to 
have  been  going  on  gradually  since  the  rupture  of  the  am- 
niotic sac  in  the  third  month,  and  accompanied  by  inflam- 
matoiy  changes  in  the  parts,  such  as  to  close  the  mouths 
ci  exposed  vessels  and  prevent  hemorrhage.    Dr.  Simp- 
son has  given  as  one  of  his  therapeutical  deductions  in  re- 
gard to  the  physiology  and  treatment  of  placenta  praevia, 
« that  inflammation  of  the  uterine  structures,  particularly 
of  the  cervix,  is  especially  likely  to  supervene  when  de- 
livery is  attended  by  placental  presentation."    This  was 
a  oomplication  of  my  first  case  also,  notwithstanding 
numerous  exhausting  hemorrhages,  and  which  retarded 
her  recovery.     In  diat  case  it  may  have  been  in  part 
due  to^  or  aggravated  by,  the  use  of  the  tampon. 

These  are  ail  the  cases  of  placenta  praevia  it  has  been 
017  good,  or  bad,  fortune  to  meet  in  a  practice  extend- 
ing over  thirty-two  years.  I  have  met  with  three  cases 
in  one  year,  and  then  again  have  passed  a  period  of  ten 
jeaxs  without  meeting  a  case. 

Analysis  of  the  cases  shows  four  of  them  central  or 
completely  covering  the  os — Cases  I.,  V.,  VI.,  and  VIII.; 
and  four  marginal — Cases  II.,  III.,  IV.,  and  VII. 

Two  cases  were  delivered  by  forceps,  one  of  central 
implantation,  in  which  case  the  child  showed  evidences 
of  having  been  dead  for  days  before  labor  set  in;  the 
olher,  a  case  of  marginal  implantation,  the  child  was  bom 
alive  and  healthy,  the  os  being  sufficiently  dilated  to 
admit  of  easy  application  of  forceps  on  my  arrival.  This 
was  the  only  living  child  of  the  whole  eight  cases. 
Three  cases  were  delivered  by  version ;  one  of  central, 
in  which  the  placenta  was  detached  for  that  purpose,  and 
two  of  marginal :  one  of  the  latter  was  complicated  by 
descent  of  funis  and  an  arm.  One  case  by  perforation 
of  placenta  and  delivery  by  presenting  feet  One  case 
bf  manual  dilatation  and  ergot  only,  and  one  requiring 
absdutely  no  interference,  a  speedy  and  easy  delivery, 
•nd  yet  die  child  was  bom  dead.  In  all  the  cases  of 
reision  or  manual  dilatation,  the  os  was  found  soft  and 
easily  dilatable,  in  accordance  with  the  observation  of  Dr. 
Bavis,  **  that  the  uterus,  firom  loss  of  blood  in  these  cases, 
is  rendered  more  passive  and  dilatable,  and  consequently 
version  is  more  easily  accomplished  than  in  any  other 
oal-presentation."  All  the  mothers  were  saved,  and 
bat  one  child.  But  how  little  bearing  the  manage- 
ment of  the  cases  during  labor  has  had  on  the  rate  of 
mortality  to  the  infants  will  be  shown  by  a  consideration 
of  die  drcomstances  of  their  histories.  Two  of  the  chil- 
dren showed  evidences  of  having  been  dead  for  days 
pievious  to  labor — destroyed  by  the  previous  hemor- 
doges,  by  asphyxia,  as  Cazeaux  states,  from  interference 
vith  dke  placental  circulation.  One  was  a  case  compli- 
cated wiUi  other  mal^presentations,  rendering  version 
necessary,  and  in  such  cases  alone  the  mortality  is  very 
pMi  and  when  superadded  to  placenta  praevia  leaves 
^  a  hopeless  chance  for  the  safety  of  the  child.  One 
vas  a  case  of  premature  delivery  at  six  months,  in  which 
^  child  would  have  been  in  any  case  lost,  because  of  its 


immaturity.  This  would  leave  but  four  cases,  or  fifty 
per  cent.,  in  which  the  accidents  or  management  of  labor 
could  be  at  all  supposed  to  have  affected  the  rate  of  mor- 
tality to  the  infants.  But  in  addition,  Case  II.  was  an  easy 
and  speedy  labor,  with  absolutely  no  call  for  interference, 
and  yet  here  the  infiint  was  bom  dead,  destroyed,  doubt- 
less, by  the  preceding  hemorrhage,'  only  a  few  hours  be- 
fore; and  again  two  more  of  the  cases  (V.  and  VI.)  were 
premature  deliveries  at  eight  and  seven  months,  in  which 
cases,  if  not  destroyed  by  the  hemorrhages,  the  chances 
of  life  to  the  children  were  correspondingly  lessened  by 
their  prematurity.  In  Cases  I.  and  V.,  the  placenta  came 
in  advance  of  the  child,  which  would  seem  to  be  a  cir- 
cumstance almost  certainly  fatal  to  the  infant,  and  very 
dangerous  to  the  mother.  Chiurchill  remarks  in  r^;ard 
to  such  cases,  "the  mother  is  not  always  lost  in  these 
cases ;"  and  again,  **•  now  it  appears  that  these  instances 
are  not  so  rare  as  was  supposed.*'  He  states  that  Dr. 
Simpson  has  coUected  one  hundred  and  thirty  cases  in 
which  the  placenta  was  either  expelled  or  extracted  first, 
and  that  in  all  ten  women  died,  or  one  in  thirteen — and 
of  one  hundred  and  ten  cases  the  infant  was  bom  dead 
in  seventy-three,  or  sixty-nine  per  cent,  and  saved  in 
thirty-three,  or  thirty-one  per  cent.  Acting  on  the  now 
generally  recommended  and  accepted  method  of  perfora- 
tion of  placenta  and  version,  this  accident  will  be  less 
likely  to  occur,  and  yet  we  venture  to  say  that  this  opera- 
tion will  not  always  prevent  the  extrusion  of  the  placenta 
in  advance  of  the  child.  I  have  had  more  than  once 
separation  of  a  normally  attached  placenta  in  the  opera^ 
tion  of  turning  for  abnormal  presentations,  and  have  lost 
the  child  probably  in  consequence.  It  will  be  no  less 
likely  to  occur  when  attached  about  the  os. 

The  one  only  child  saved  of  my  eight  cases  was  de- 
livered by  the  generally  disapproved  method  of  the  for- 
ceps. No  doubt  the  timely  and  opportune  application 
was  proper  and  correct  in  this  case.'  The  summary  of 
results  from  the  cases  given  in  the  papers  to  which  I  have 
made  reference  is  as  follows : 


i  Number 
of  cases. 

1 

Mothers'     Per     j  Children 
saved.  |.  cent    |  saved. 

1"              1 

Per 
cent. 

T.  C.  Smith 3 

D.  C.  Davis 17 

Hoffman 1     46 

My  own 8 

3         100 
17         100 
41           89 

8     I    100 

2 
I 

67 

6 
"•5 

;   74 

69 

97.25 

4 

14 

These  results,  so  far  as  any  conclusions  may  be  legit- 
imately drawn  from  such  meagre  records,  show  much 
more  fiivorably  for  the  mother,  and  contrariwise  for  the 
infant,  than  the  results  commonly  given  by  writers ;  and 
that  while  there  seem  to  be  good  reasons  for  believing 
there  has  been  an  improvement  in  the  chances  for  the 
mother,  that  no  such  encouragement  is  warranted  as 
regards  the  child ;  nor  from  a  consideration  of  the  nature 
and  circumstances  of  the  accident  does  it  seem  probable 
that  any  great  improvement  in  that  respect  can  be  at- 
tained for  the  following  reasons : 

1.  If  my  cases  are  a  fair  average  exhibit,  from  twenty- 
five  to  thirty-three  per  cent,  of  all  will  be  destroyed  by 
disturbances  of  the  circulation  previous  to  labor. 

2.  From  Simpson's  statistics  twenty-five  per  cent,  of 
all  cases  will  be  complicated  with  other  mal-presenta^ 
tions,  compromising  the  life  of  the  child  in  a  very  large 
proportion  of  them. 

3.  From  twenty-five  to  thirty-five  per  cent  of  all  will 
be  premature  births.  If,  then,  to  these  circumstances  we 
add  the  risks  from  hemorrhage  in  labor,  besides  the  risks 
from  version  and  other  artificial  interiference  and  aids, 
we  can  understand  that  the  risks  to  the  child  must  al- 
ways remain  so  great  as  to  permit  of  the  safe  delivery  of 
but  a  small  proportion,  and  we  may  also  understand  why 


92 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


nature,  in  her  beneficence,  looking  to  the  safety  of  the 
mother  in  the  great  majority  of  the  cases,  probably  pre- 
fers the  sacrifice  of  the  o£fspriug  by  an  early  abortion. 

In  conclusion,  what  are  the  causes  of  this  accident  of 
parturition  whidi,  despite  of  all  proposed  methods  of 
management,  continues,  in  its  fatality  to  children,  as 
merciless  as  the  execution  of  the  Herodian  edict  for  the 
slaughter  of  the  innocents,  and,  more  merciless  than  that, 
destroys  also  a  large  percentage  of  the  mothers,  causing 
lamentation  and  mourning  in  households,  and  anxious 
care  and  harassing  disappointment,  and  vexatious  dis- 
satisfaction to  the  physician  with  the  results  of  his  most 
energetic  and  conscientious  efforts  to  bring  the  labor  to 
a  safe  and  happy  termination,  not  only  as  re^rds  the 
mother  but  to  save  her  o£fspring  ?  The  condition  is  un- 
physiological,  and  I  should  suppose  peculiar  in  and  pos- 
sible only  to  the  human  female,  unless,  peiiiaps,  the  quad* 
rumana  may  be  exposed  to  it.  Writers  have  particiilarly 
called  attention  to  the  fact  of  the  frequent  complication 
of  this  accident  with  other  coincident  mal-presentations. 

Dr.  Simpson^  as  we  have  stated,  gives  a  table  of  twenty- 
three  cases  of  other  mal-presentations  in  a  table  of  ninety- 
one  cases  of  placenta  praevia.  Dr.  T.  Gaillard  Thomas,  in 
a  clinical  lecture  on  "  Causes  and  Treatment  of  Abor- 
tion," published  in  the  New  York  Medical  Journaly  Janu- 
ary 24,  1884,  states  that  '^  there  are  two  great  causes  of 
abortion — ^first,  a  posterior  displacement  of  the  uterus, 
which  interferes  with  a  proper  development  of  the  organ ; 
second,  syphilis.'*  But  the  first  is  the  only  one  which  has 
any  relevancy  to  our  subject,  and  this  because  it  is  evi- 
dence from  eminent  authority  of  that  condition  as  the 
most  frequent  cause  of  abortion  which  we  regard  as  the 
most  prolific  cause  of  mal-positions  and  placenta  prsevia, 
not  posterior  displacement  of  itself,  but  the  cause  of  pos- 
terior and  of  other  displacements.  For  what  is  the  cause 
of  these  displacements  ? 

The  cause  is  in  the  increased  bulk  and  weight  of 
the  uterus  firom  subinvolution,  as  is  also  that  of  un- 
natural relaxation  and  patency.  In  a  paper  before  this 
Society,  two  years  ago,  on  some  mal-presentations,  I 
I  stated  this  as  the  prolific  cause  of  mal-presentations, 
placenta  praevia,  ancl  abortions.  These  accidents — mal- 
presentations  and  placenta  praevia — occur  for  the  most 
part  in  multiparas  or  in  multipregnant  women,  and  fre- 
quent conceptions,  but  more  especially  repeated  abor- 
tions, are  the  most  prolific  cause  of  unnatural  relaxation 
and  patency,  and  are,  again,  the  cause  of  too  frequent 
conceptions.  A  relaxed  uterus  with  an  enlarged  and 
patulous  cavity  fails  to  arrest  and  detain  the  ovum  on 
its  arrival  in  the  uterus  from  the  Fallopian  tubes,  or  it  is 
washed  down  by  the  menstrual  secretions,  or  is  more 
readily  displaced  by  the  movements  of  the  mother,  or  by 
any  violence  or  shock,  and  is  thereby  caused  to  form  an 
unnatural  attachment,  and  the  same  conditions  may 
favor  unnatural  positions  in  the  developing  and  growing 
^erm  from  the  very  commencement  of  intra-uterine  ex- 
istence. 

An  Old  Mode  of  DErBcriNG  Kabibs. — To  enable  a 
person  who  had  been  bitten  by  a  dog  to  ascertain  whether 
or  not  the  animal  was  rabid,  the  Universal  Magazine^  a 
London  monthly  publication,  in  its  issue  of  November, 
^  753>  published  the  following,  which  is  accredited  to  "  The 
Memoirs  of  the  Royal  Academy  of  Sciences  at  Paris:'* 
*•  When  a  person  hath  been  bitten  by  a  dog  that  is  ap- 
prehended to  be  mad,  it  commonly  happens  that  the  dog 
18  killed  before  one  is  assured  of  his  condition,  and  the 
person  bitten  continues  in  a  cruel  uncertainty.  Mr. 
Petit,  the  surgeon,  hath  an  expedient  for  putting  an  end 
to  this  uneasiness.  He  rubs  the  throat,  the  teeth,  and 
the  gums  of  the  dead  dog  with  a  piece  of  meat  that  hath 
been  dressed,  taking  care  that  there  be  no  blood  to  stain 
ity  and  then  ofiers  it  to  a  living  dog.  If  he  refuses  it 
with  crying  and  howling,  the  deaid  dog  was  certainly  mad ; 
but  if  the  victuals  have  been  well  received  and  eaten, 
there  is  nothing  to  fear." 


ON    THE  UNTRUSTWORTHINESS   OF  FLUID 
EXTRACTS, 

With  Practical  Notes  Rbgarding  Rhus  Toxi- 
codendron, Pulsatilla,  Cereus  Bonplandi,  and 
OTHER  Plants. 

By  N.  L.  north,  M.D., 

BROOKLYN,   N.  Y. 

"  Untrustworthy  '*  ought  to  be  written  after  the  name 
of  many  of  the  fluid  extracts  of  medicinal  plants  as 
usually  found  on  our  apothecaries'  shelves.  I  have  a 
habit  of  tasting,  at  a  subsequent  visit,  of  nearly  all  the 
medicines  I  prescribe,  and  I  find  there  is  a  large  number 
of  the  fluid  extracts  in  many  of  the  officinal  and  ud- 
officinal  V  forms  prepared  for  our  use  by  the  pharmacists 
which  taste  exactly  alike.  That  taste  is  a  peculiar,  stale, 
dirty,  gritty  one,  often  entirely  wanting  in  the  special 
aroma  peculiar  to  each  plant  in  the  green  state ;  and 
just  here,  I  make  no  doubt,  is  the  secret  of  the  untrust- 
worthiness  of  many  of  these  "medicines."  Instead  of 
the  fluid  extract  being  made  from  the  recent  or  fresh 
green  herb,  it  is  too  often  made  from  a  dried,  more  or 
less  inert  plant,  from  which  the  volatile,  and  often  the 
active  principle  has,  perhaps,  wholly  evaporated. 

This  fact  will  no  doubt  go  far  to  explain  the  sentence, 
"  The  medical  virtues  of  this  plant  are  too  uncertain  to 
inspire  any  confidence  in  it,"  or  something  meaning  the 
same  thing,  so  often  found  in  the  di^ensatories.     To 
particularize :    The  article  rhus  toxicodendron,   which 
is  dismissed  by  the  National  Dispensatory  with  the  re- 
mark quoted  above,  after  being  thought  worthy  to  be 
considered  officinal  under  the  head  of  Toxicodendron,  is,   * 
there  can  be  no  doubt,  a  plant  of  definite  and  consider- 
able power  medicinally,  if  rightly  prepared  and  properly 
used.     Dr.  Thomas  Giflbrd,  of  Laurel,  Ind.,  speaks  veiy 
highly  of  its  curative  action  in  sciatica,  having  used  it 
successfully  for  many  years,  even  in  cases  of  one,  two, 
and  three  years'  standing.     Dufresnoy  called  attention 
to  the  rhus  toxicodendron  as  a  remedy  in  herpetic  and 
eczematous  diseases  as  early  as  1 798.     Phillips,  in  his 
work  on  *<The  Materia  Medica,  etc.,  of  the  Vegetable 
Kingdom,''  refers  to  the  rhus  as  a  very  powerful  thera- 
peutic a^ent  in  "various  subacute  and  chronic  rheu- 
matic affections  of  the  fibrous  tissues  generally."     Dr. 
H.  G.  Fiffard,  of  New  York,  in  an  editorial  note  in  Dr. 
Phillips'  book,  confirms  its  usefulness.    Speaking  of  the 
probable  error  sometimes  made  by  physicians,  mistaking 
the  '^  worse-at-night "  rheumatism  for  syphilitic  rheu- 
matism. Dr.  Piffard  says :  "  In  a  number  of  these  cases 
we  have  obtained  most  decided  and  prompt  relief  from 
rhus."     The  whole  matter  turns  upon  the  mode  of  prep- 
aration.    The  officinal  fluid  extract,  of  which  it  is  ad- 
vised to  give  from  one  to  ten  drops,  is  probably  good  for 
nothing.     Dr.  Gifford  makes  a  strong  tincture  (one  part 
to  two  of  alcohol)  from  the  green  herb,  gathered  the  last 
of  May  or  the  first  of  June,  previous  to  the  flowering  of 
the  plant.     It  is  gathered  after  sundown  of  a  lowery  day. 
He  likely  in  this  way  preserves  the  toxicodendric  acid. 
Of  this  tincture  he  gives  from  one-tenth  to  one-filth  of  a 
minim  in  a  spoonfiil  of  water  twice  a  day,  and  in  some 
cases  he  advises  even  smaller  doses.     Dr.  Phillips  ad- 
vises a  tincture  made  by  macerating  one  part  of  fresh 
leaves  in  two  parts  of  alcohol ;  of  this  he  advises  a  small 
fraction  of  a  minim  in  rheumatic  and  cutaneous  afifec- 
tions.    The  tincture  of  the  German  Pharmacopoeia  is 
made  from  five  parts  of  the  fresh  leaves  to  six  parts  of 
alcohol. 

Again,  in  the  National  Dispensatory  we  find  after  the 
description  of  Pulsatilla,  lately  made  officinal,  ^'  No  suf- 
ficient grounds  exist  for  its  use  in  therapeutics."  Never- 
theless Pulsatilla  is  often  spoken  of  in  the  journals  and 

1 1  mention  in  diii  ooonectioa  die  so-called  ^m^jficmml  mBdicbud^preparatiiHis 
because  it  is  a  well-knoMrn  ikct  that  there  are  a  larve  number  of  what  tne  makers  ol 
our  pharmacopoeias  fiul  to  recogniae  as  offieituU,  lac  decade  after  decade,  whacfa 
are,  nevertheless,  "in  the  shops,**  and  oonstandy  being  used  by 
practitioners. 


July  26,  18^.] 


THE  MEDICAL  RECORD. 


93 


10  otber  waj$  by  such  men  as  Sturgis^  Pifiard,  and  Fox, 
of  New  York,  and  Borchiem,  of  Atlanta,  Ga.,  as  a 
jemedy  of  much  value  in  glandular  inflamniations  and 
particularly  in  epididymitis.  Phillips  {"  Vegetable 
Materia  Medica  "^^^  after  advising  its  use  in  several  in- 
flammatory conditions,  says,  '*  The  fluid  extract  is  un- 
reliable," and  recommends  a  tincture  made  of  equal 
parts  d  the  expressed  juice  and  alcohol,  of  which  he 
ffives  from  one-tenth  to  five  minims. 

There  is  another  article  or  herb  product  which  I  have 
been  in  the  habit  of  using  and  recommending  for  some 
eight  to  ten  years,  more  especially  for  cardiac  insuffi- 
oency,  that  I  fear  may  soon  be  hard  to  obtain  in  its 
proper  form,  as  I  learn  that  one,  at  least,  of  the  drug 
manufacturers  is  already  preparing  and  recommending  a 
fluid  extract  of  it.     I  refer  to  the  cereus  bonplandi.     It 
is  not  mentioned  in  any  of  the  regular  works  on  Materia 
Medica  to  which  I  have  access.     I  first  saw  it  spoken  of 
in  the  Medical  Brief  hy  a  Dr.  Goss,  who,  I  think,  is  an 
"eclectic"    The  preparation  he  recommended  and  the 
one  I  have  always  used,  when  I  could  get  it,  is  a  strong 
liflctnre  of  the  green  herb,  prepared  by  a  German  drug- 
gist, R.  E.  KuDze,  606  Third  Avenue,  New  York.     The 
tincture  should  have  a  decidedly  green  tint.     There  is  a 
preparation  of  a  less  decided  tint,  probably  made  from  a 
partially  dried  herb,  which  is  occasionally  used,  but  is 
scarcely  reliable.  The  homoeopathists  have  a  brown  prepa- 
lation  of  the  cereus  grandiflora  (night-blooming  cereus) 
that  1  find  sometimes  substituted,  but  which  has  almost 
DO  value  in  my  hands.     The  green  tincture  of  Dr.  Kunze 
is  one  of  the  most  satisfactory  remedies  I  use.     In  ten- 
drop  doses,  three  or  four  times  a  day,  it  will  correct 
^palpitation"    and  irregular  action  of  the  heart  from 
6mctioDal  derangement  with  so  much  certainty  to  the 
physician  and  comfort  to  the  patient,  as  to  be  a  source 
of  profound  satisfaction.     It  seems  to  give  tone  to  the 
nerves  and  centres  controlling  the  heart's  movements. 
Even  in  organic  disease  of  the  heart,  with  valvular  in- 
safficieocy,  whether  resulting  from   rheumatic  endocar- 
ditis or  otherwise,  this  remedy,  through  its  steadying 
pover,  particularly  in  young  subjects,  gives  positive  re- 
lief, and  in  some  cases  appears  to  exert  a  curative  action. 
There  are  many  other  plants  and  plant  products  of 
more  or  less  acknowledged  usefulness  which  are  gradu- 
ally falling  into  disuse  because,  possibly,  of  the  prevalent 
niodes  of  preparation.     The  Phytolacca  decandra,  a  suc- 
colent  plant,  i$  a  powerful  remedial  agent  in  local  in- 
^mmaXoiy  conditions — ^notably  in    mastitis — used  in- 
ternally and  externally,  and  yet  the  fluid  extract  of  the 
^ed  plant  is  of  doubtful  utility.     The  silphium  gummi- 
feram  (rosin  weed)  has  probably  some  virtue  in  bronchial 
catarrh  and  like  affections  \  I  saw  an  account  from  a 
French  journal,  some  years  ago,  in  which  it  was  thought 
to  have  cured  phthisis.     I  have  used  it  considerably,  with 
apparent  benefit,  in  phthisical  cases.     It  is  used  in  the 
pruiie  districts  of  the  West  as  a  domestic  remedy,  and 
far  horses  with  the  '^  heaves.''  The  plant  probably  has  vir- 
toe,  but  the  only  form  in  which  we  can  get  it  is  the  fluid 
extiact,  and  that,  as  in  the  case  df  the  others  named,  and 
of  many  more  that  might  be  named,  promises  but  little. 
I  have  before  me  a  long  list  of  fluid  extracts  as  prepared 
hf  one  of  the  leading  wholesale  dru^  manufacturers  of 
New  York,  of  which  the  dose  list  in  itself  is  suspicious, 
ia  that  in  many  cases  it  would  be  impossible  to  follow 
directions  without  danger,  if  the  remedies  were  made,  as 
^should  be,  with  the  requisite  caution  and  care  to 
(tein  all  of  curative  value  each  individual  plant,  at  its 
best,  afi:>rds.i» 

1  desire  to  add,  what  is  evidently  apparent  from  what 
1  have  already  written,  that  I  make  no  claim  to  practical 
phffmacy.  My  remarks  should  not  be  received  as  being 
Dade  in  the  spirit  of  criticism,  but  as  an  expression  of 
desire  that  the  evils  referred  to  might  be  corrected  by  an 
cibrt  on  the  part  of  our  drug-makers  and  pharmacists  to 
one  thoroughly  study  indivuiual  drugs  and  plants,  and 
» treat  them  as  to  capture  that  in  them,  whether  it  be 


one  or  many  virtues  or  "  active  principles,"  as  that  there 
may  be  results  commensurate  with  the  necessities  caused 
by  disease,  and  as  far  as  may  be  possible  uniform  results 
when  the  medicine  is  properly  administered. 


A  STAPHYLOMATOUS  EYEBALL  ENUCLE- 
ATED  FOR  SYMPATHETIC  IRRITATION, 
CALCIFIED  CORNEA,  ETC. 

Reported  by  DAVID  WEBSTER,  M.D., 

PROFESSOR  OP  OPHTHALMOLOGY  IN  THE  NEW  YORK   POLYCUNIC,  BTC. 

Mrs.  Henry  M ,  sixty-  three  years  of  age,  was  re- 
ferred to  Dr.  C.  R.  Agnew  by  her  *family  physician  on 
March  24,  1883,  for  advice  in  regard  to  her  eyes.  She 
gave  a  history  of  having  caught  cold  while  suffering  from 
an  attack  of  the  measles  when  she  was  seven  years  old. 
Both  of  her  eyes  were  severely  inflamed  then  and  for 
some  time  afterward.  From  present  appearances  it  is 
evident  that  she  had  keratitis  and  cyclitis.  The  cornea 
of  the  left  eye  is  protuberant  from  softening  and  dilata- 
tion of  the  eye-wall  in  the  ciliary  region,  and  presents 
two  large  patches  of  dense,  apparently  cicatricial  opacity. 
The  iris,  indistinctly  seen,  is  shaky,  showing  a  probable 
dislocation  of  the  lens  and  a  fluid  vitreous,  and  the  eye 
is  without  perception  of  light.  The  right  eye  has  corneal 
opacities  from  old  keratitis,  and  is  highly  myopic  with 
greatly  reduced  vision  from  irregular  astigmatism.  Both 
eyes  have  been  irritable  for  the  last  few  days. 

Enucleation  of  the  left  eye  was  advised  at  this  visits 
but  was  deferred  by  the  patient  for  nearly  a  year,  during 
which  time  she  was  troubled  with  recurring  attacks  of 
conjunctivitis  affecting  both  eyes.  At  length  she  con- 
sented to  enucleation,  and  the  operation  was  performed 
by  Dr.  Agnew  on  February  28,  1884. 

The  eyeball,  which  seemed  to  be  much  elongated  an- 
tero-posteriorly,  was  put  into  Muller's  fluid,  and  was 
examined  by  Dr.  T.  Mitchell  Prudden,  who  on  June  13, 
1884,  made  the  following  report : 

'•  Macroscopical  examination. — ^The  eye  was  enlarged, 
measuring  2.7  ctm.  transversely  and  3.3  ctm.  antero-pos^ 
teriorly.  On  section,  the  lens  is  loosely  attached  and 
lies  considerably  behind  the  iris  at  one  side  of  the  an- 
tero-posterior  axis  of  the  globe.  There  is  attachment  of 
the  iris  to  the  cornea  at  one  side.  The  vitreous  is  soft 
and  partially  disintegrated.  Depression  of  the  optic  /o- 
pilla  1.5  mm.  deep.  Retina  on  one  side  partially  de- 
tached from  the  choroid. 

^^Microscopical  examination, — ^I'he  anterior  epithe- 
lium of  the  cornea  and  the  substantia  propria  are  uneven, 
being  in  some  places  thinned  and  in  others  thickened. 
The  substance  of  the  cornea  shows  in  the  anterior  layers, 
chiefly  on  one  side,  extensive  infiltration  with  larger  and 
smaller  irregularly  spheroidal  masses  and  globules  of  cal- 
cium carbonate  (carbonic  acid  given  off  on  addition  of 
hydrochloric  acid).  Cornea  also  irregularly  infiltrated 
with  spheroidal  and  variously  shaped  cells. 

"  The  /rtf,  which  is  in  part  atrophied  and  much  dis- 
torted, is  firmly  adherent  tp  the  cornea  a  little  to  one  side 
of  the  antero-posterior  axis  of  the  globe,  over  a  small  area. 

"  The  ciliary  body  is  drawn  backward,  flattened,  dis- 
torted, and  partially  atrophied. 

"  The  lens  shows  in  a  few  places  hyaline  degeneration 
of  the  fibres. 

"  The  choroid  is  normal  except  for  moderate  conges- 
tion of  blood-vessels  in  places. 

"  The  retina^  in  general,  appears  normal,  except  that 
there  is  slight  detachment  on  one  side,  and  scattered 
areas  of  oedema,  particularly  of  the  external  molecular 
layer.  There  is  atrophy  of  the  retina,  however,  about 
the  glaucomatous  depression  of  the  optic  nerve  entrance. 

'*  Anatomical  diagnosis. — Keratitis  with  calcification 
in  anterior  layers  of  cornea,  flattening,  and  atrophy  of 
ciliary  body,  anterior  synechia,  displacement  of  lens  with 
commencing  degeneration,  moderate  congestion  of  cho- 
roid and  slight  detachment  of  retina,  glaucomatous  exca- 
vation of  optic  disk." 


94 


THE  MEDICAL  RECORD. 


[July  26,  1884, 


ELECTROLYSIS    IN   STRICTURE. 
By  H.  W.  STREETER,  M.D., 

ROCHBSTBIt,   N.  Y. 

I  HAVE  seen  such  remarkable  statements,  from  time  to 
time,  of  the  effects  of  electrolysis  in  the  treatment  of 
urethral  stricture,  that  I  am  constrained  to  give  the  re- 
sults of  my  experience.  I  would  premise  by  saying  that 
I  regard  any  contraction  of  the  urethra  smaller  than  the 
normal  meatus,  as  tested  by  bulbous  sounds,  as  a  strict- 
ure ;  and  that  no  case  is  cured  as  long  as  such  contrac- 
tions can  be  detected.  For  although  the  symptoms  may 
be  relieved  for  the  time,  they  are  liable  to  return  at  any 
time  upon  slight  provocation.  No  recognized  authority 
upon  surgery  or  electricity  with  which  I  am  acquainted, 
claim  any  such  results  as  these  writers  in  the  journals. 
Otis  says,  in  a  private  communication  to  the  writer,  he 
thinks  it  more  likely  to  cause,  than  to  cure  stricture. 
Keyes  writes  that  he  had  tested  it  in  a  series  of  cases  in 
Charity  Hospital  and  found  it  worthless.  Particulars  of 
these  cases  are  found  in  Keyes  and  Van  Buren  on  "Ven- 
ereal Diseases."  Rockwell,  one  of  the  authors  of  Beard 
and  Rockwell's  "Electricity,"  speaks  in  very  guarded 
terms  of  its  effects. 

I  determined  to  try  it  as  occasion  should  present.  I 
tried  it  in  all  upon  seventeen  patients,  several  of  whom 
had  heard  of  it,  while  the  others  were  bitterly  opposed 
to  urethrotomy,  and  all  had  become  dissatisfied  with  dila- 
tation. With  weak  currents  of  six  to  eight  cells,  at  in- 
tervals of  eight  to  fourteen  days,  I  produced  no  effect ; 
with  stronger  currents,  the  only  eflfect  was  irritation  and 
more  or  less  inflammation.  The  calibre  of  these  strict- 
ures varied  from  six  to  sixteen,  and  my  applications  varied 
from  six  to  twelve  in  each  case.  In  thirteen  of  the  cases 
I  used  currents  which  could  be  barely  felt  by  the  patients 
(as  advised  by  the  writers  referred  to),  and  created  no  ir- 
ritation. .  With  four  patients,  who  wanted  anything;  rather 
than  the  knife,  and  in  whom  repeated  weak  applications 
failed,  I  tried  the  stronger  currents,  with  only  bad  e£fects. 
All  of  these  cases  I  afterward  cut  with  Otis'  dilating  ure- 
throtome, with  the  result  of  producing  immediate  relief, 
and  in  most  of  the  cases,  I  have  reason  to  think,  perma- 
nent cure.  In  no  other  similar  affection — stricture  of 
the  oesophagus,  of  the  rectum,  or  organized  abnormal 
tissue,  have  any  such  results  been  claimed  for  electroly- 
sis when  applied  in  such  weak  and  superficial  method  as 
described  in  the  articles  referred  to.  And  I  know  of 
no  reason — clinical,  physiological,  or  therapeutical — why 
such  results  should  be  expected,  or  why  the  urethra 
should  be  an  exception  to  all  the  other  tissues  of  the 
body.  Any  deviation  from  the  normal  calibre  of  the  ure- 
thra is  liable  to  produce  local  and  reflex  symptoms,  which 
will  continue  as  long  as  the  stricture  remains.  Recent 
strictures  may  be  relieved,  and  some  cured,  by  dilatation, 
but  I  do  not  think  either  reason  or  experience  leads  us  to 
expect  that  many  strictures  can  be  permanently  cured  by 
dilatation,  and  we  all  know  how  unsatisfactory  even  is 
the  relief  given  by  sounds.  Urethrotomy  by  Otis' 
method  is  based  on  common  sense,  and  should  theoreti- 
cally cure  stricture.  It  may  be  said  of  it,  in  the  great 
majority  of  cases,  that  it  is  simple  and  easy  of  perform- 
ance, safe,  less  painful  than  dilating  by  a  full-sized  sound, 
1.^.,  one  large  enough  to  do  any  good,  produces  imme- 
diate relief,  and  if  not  permanent  cure  in  every  case,  it  i§ 
more  effectual  than  any  other  method  yet  devised 


Medical  Students  in  Germany. — The  following 
figures  show  the  number  of  medical  students  at  the  chief 
German  universities  during  this  term :  Berlin,  924,  in- 
cluding 20  from  America,  6  from  Asia,  and  2  from 
Africa;  Jena,  162  ;  Bonn,  289  ;  Konigsberg,  267  ;  Halle, 
282;  Grtittingen,  189;  Giessen,  126;  Tiibingen,  224; 
Strassburg,  172.  The  autumn  cyclus  of  the  holiday  course 
of  lectures  for  practising  medical  men  will  take  place  at 
Berlin  from  September  24th  to  the  end  of  October. 


A  PLEA  FOR  THE  USE  OF  DELICATE  TESTS 
FOR  ALBUMEN  IN  URINE. 

By  GEORGE  B.  FOWLER,  M.D., 

PKOFRSSOS    OP    PHYSIOLOGICAL    CHBMISTRY,    NKW    YOKK     POLYCLINIC;    VISITING 
PKYStaAN  TO  THB  NEW  YORK  IMPANT  ASYLUBL 

Whether,  in  every  instance,  the  presence  of  albumen  in 
urine,  in  any  proportion,  is  necessarily  the  signal  for  an 
alarming  prognosis,  is  a  question  destined  to  receive 
much  attention  in  the  near  future.  Yet,  whatever  be  the 
verdict,  I  am  convinced  that  albuminuria  is  not  a  physio- 
logical condition.  And,  while  many  apparently  healthy 
people  may  present  this  symptom  in  a  given  case,  we 
certainly  are  not  yet  prepared  to  say  what  will  be  the  ul- 
timate result. 

To  be  in  perfect  health  implies  a  condition  easier  to 
comprehend  than  define.  Many  trivial  indispositions 
connected  with  various  organs  have,  from  their  tendency 
to  pass  off,  taught  us  indifference.  But  ignorance  on 
the  part  of  the  patient  of  the  possible  significance  of  his 
slight  symptoms,  and  failure  or  inability  of  the  physician 
to  apply  minute  methods  of  investigation,  have  too  often 
proved  the  source  of  future  regret  and  disaster. 

If  we  are  dealing  with  a  supposed  "  fimctional "  case, 
and  look  anxiously  for  the  gradual  disappearance  of  the 
morbid  chemical  reaction  of  the  urine,  how  much  more 
does  it  not  behoove  us  to  be  familiar  with  those  delicate 
processes,  by  whose  means  we  shall  be  enabled  to  fol- 
low the  intruder  across  the  pathological  territory,  and 
back  into  physiological  bounds. 

And,  moreover,  if  it  is  ever  to  be  established  that  a 
trace  of  albumen  in  the  urine  is  compatible  with  health, 
it  will  be  by  a  skilful  use  of  the  more  delicate  tests.  I 
am,  therefore,  not  in  harmony  with  those  who  say  that 
heat  and  nitric  acid  are  sufficient ;  for  this  is  equivalent 
to  the  dogmatical  assertion  that  where  these  reagents 
fail  there  is  no  albuminuria.  It  is  a  significant  fact,  in 
this  connection,  that  neither  albumen  nor  any  of  its  allied 
compounds  are  met  with,  under  normal  conditions,  in  any 
of  the  excretions.  In  fact,  the  loss  of  these  substances  is 
expressly  guarded  against  bv  one  of  their  characteristic 
qualities,  namely,  indiffusibility. 

The  only  albuminous  derivatives  capable  of  ready 
transudation  are  peptones  ;  yet,  although  these  are  pro- 
duced in  such  great  quantity  in  the  stomach  and  intes- 
tines during  digestion,  their  loss  is  prevented  by  the  pro- 
vision that  they  must  pass  through  the  liver  before 
entering  the  general  circulation.  In  the  liver  they  are 
transformed  into  matters  having  no  tendency  to  escape. 

As  regards  the  reagents  most  to  be  relied  upon  in 
testing  for  albumen  in  urine,  I  will  simply  say  a  word, 
for  much  has  recently  been  written  upon  this  matter. 

In  order  to  determine  the  comparative  delicacy  of  some 
of  the  methods,  I  used  the  serum  of  ox-blood,  carefully 
drawn  from  a  firm  clot,  and  mingled  it  in  var}'ing  propor- 
tions with  normal  urine.  Now,  the  composition  of  this 
serum  is  as  follows  :  Water,  90  parts ;  proteids,  8  ;  fats, 
salines,  etc.,  2  =  100  pfu-ts. 

The  proteids  consist  of  two  forms  of  albumen,  serum-al- 
bumen and  paraglobulin,  in  about  equal  proportions.  As 
these  two  substances  are  always  associated  in  albumin- 
ous urine,  and  respond  to  the  tests  to  be  enumerated, 
their  distinctive  qualities  need  not  be  dwelt  upon,  and 
they  are  together  reckoned  as  albuminous.  But  the  trial 
solutions  having  been  made  with  serum  and  water,  in 
order  to  know  the  proportion  of  albumen  detected,  we 
must  go  through  with  a  little  calculation  based  on  the 
proportion  of  albumen  present  in  the  serum.  This  has 
been  done,  and  the  results,  as  given  below,  are  for  albumen 
calculated  as  dry.  I  speak  of  this  because  most  of  those 
who  have  gone  over  this  ground  leave  us  in  the  dark 
whether  with  any  given  method  (having  used  serum  or 
white  of  egg)  the  percentage  detected  means  the  per- 
centage of  serum  or  white  of  egg  respectively,  or  the 
actual  proportion  of  albumen  present. 

As  a  result  of  numerous  and  very  careful  trials  with 


July  26,  1884.] 


THE  MEDICAL  RECORD. 


95 


beat,  nitric  add,  picric  acid,  acidulated  brine,  potassium, 

fcrrocyanide  and  acetic  acid,  potassio-mercuric  iodide, 
and  other  methods,  I  found  the  following  to  be  their  re- 
spective capabilities  : 

Heaiy  in  neutral  solution,  fails  with  .018  of  one  per 
cent;  in  slightly  acid  solution,  reacts  with  .018  of  one 
per  cent 

Acidulated  brine^  about  same  delicacy  as  heat 

Picric  c^id^  if  carefully  applied,  will  detect  .008  of  one 
per  cent.  But  being  of  low  specific  gravity  it  is  some- 
times  difficult  to  employ  the  contact  method  with  it.  Its 
decided  yellow  color  masks  its  effects  and  interferes  with 
its  delicacy. 

Nitric  cuid  is  satisfactory  with  Tan  .008  of  one  per 
cent  solution  of  albumen,  if  the  contact  method  is  em- 
ployed The  greater  the  diameter  of  the  test-tube,  and 
tbe  longer  it  stands  perfectly  still,  the  more  marked  is 
the  ring  of  coagulation.) 

Potassium^  ferrocyanide^  and  acetic  acid. — ^The  urine 
being  first  made  decidedly  acid,  and  then  a  few  drops  of 
the  ferrojgramde  added,  feint  clouds  of  opalescence  will 
be  seen  in  an  .008  of  one  per  cent,  solution  of  albumen. 

Potassifhmercuric  iodide  *  gives  a  very  manifest  reaction 
with  a  .004  of  one  per  cent,  solution,  and,  hence,  is  the 
most  delicate  of  all. 

It  should  be  borne  in  mind  that  both  picric  acid  and 
the  potassio-mercuric-iodide  solution,  also  precipitate 
peptones,  quinine,  morphia,  strychnia,  and  perhaps  other 
alkaloids,  and  the  former  may  throw  down  the  urates. 
All  of  these  precipitates,  however,  completely  disappear 
en  heating  the  solution,  thereby  enabling  us  easily  to 
distinguish  them  from  albumen. 

These  percentages  may  seem  to  some  very  small  and 
not  worth  detecting ;  but  I  contend  that,  pathologically 
considered,  they  are  by  no  means  insignificant.  Let 
OS  look  at  it  practically.  Serum  contains  about  eight 
per  cent,  of  albumen  (or  proteids  precipitable  by  the 
foregoing  means).  We  pass  about  1,500  c.a  of  urine  per 
day,  and  urinate  about  six  times.  That  would  be  about 
150  c.c  for  each  time.  Now,  i  c.c.  of  serum  in  each  of 
these  voidings,  or  6  c.c.  in  the  whole,  would  give  us  .031 
of  one  per  cent,  of  albumen. 

So  we  see  that,  although  the  percentage  of  albumen 
may  be  down  among  the  thousandths,  an  appreciable 
quantity  of  blood-serum  is  thereby  represented.  And,  to 
my  mind,  the  leakage  of  6  c.c.  of  serum  through  the 
kKlneys  per  day  is  abnormal,  and  suggests  danger  ahead. 
At  any  rate  it  is  well  to  be  able  to  know  it,  so  as  to  keep 
a  sharp  lookout 

For  those  who  may  desire  to  learn  more  regarding  the 
origin  suid  development  of  these  new  tests,  and  who  are 
not  familiar  with  the  precautions  to  be  observed  in  their 
application,  I  append  a  brief  bibliography  : 

"  Urine  Testing,"  Lancet  (Am.  ed),  May,  1883,  P- 
466;  Pavy :  "Urinary  Test  Pellets,"  Lancet  (Am.  ed.), 
April,  1883,  P-  318;  Roberts  :  "Acidulated  Brine  Test 
fcf  Albumen,"  Ztf«^^/,  December,  1882,  p.  438;  John- 
son: "Picric  Acid  as  Test  for  Albumen,*' etc., -ffr/VwA 
Medical  fourmdy  March  17,  1883,  p.  504;  Johnson: 
"Picric  Acid  as  a  Means  of  Distinguishing  Albumen  from 
Peptone,"  British  Medical  Journal^  March  31,  1883,  p. 
64;  Ralfe:  "Picric  Acid  as  a  Urinary  Test,'* -5r//tfi4 
Medical  Journal^  April  7,  1883  ;  Johnson  :  "  Picric  Acid 
as  a  Test  for  Albumen,"  British  Medical  Journal,  May 
S,  1883  ;  Ralfe  :  "  Peptones  in  Urine,"  British  Medical 
Jmrnal,  May  12,  1883;  Oliver:  "On  Bedside  Urinary 
Tests,*'  Lancet  (Am.  ed.),  April,  1883. 


A  SATIRICAL  medical  review,  called  Dr.  SangradOj  is 
published  in  Madrid.  It  was  begun  on  November  last, 
ttid  has  appeared  ey^ry  fifth  day  since  that  time. 

'Fomfat: 

Pjtiodid  .  332  gnn. 

njmg.  bKhlond 1.35  gnn. 

Aad  acetic. ao  cc.| 

AqBadettiLut.ft xoocc. 


Food  for  thr  Febrile.  —  Dr.  Zasetzky  {Vratch) 
considers  the  quesdons  of  food  and  drink,  air,  and  rest, 
for  the  febrile.  He  unconditionally  repudiates  the  old 
doctrine  of  keeping  the  patients  on  a  **  hungry  "  diet, 
consisting  of  carbohydrates,  and  insists  on  the  necessity 
of  their  sufficient  feeding.  Albuminates,  fats,  and  car- 
bohydrates must  be  represented  in  the  food  for  the  feb- 
rile exactly  in  the  same  proportion  as  in  the  food  for 
the  healthy.  He  supports  this  demand  by  the  results 
of  observations,  according  to  which  febrile  patients  as- 
similate albuminates,  fats,  and  carbohydrates  in  the 
same  degree  as  healthy  subjects.  Food  must  be  riven 
to  the  febrile  in  comparatively  small  amounts  at  a  time  ; 
it  must  be  mechanically  prepared  for  digestion  and 
must  well  satisfy  individual  tastes  and  habits  of  the  pa- 
tients. The  febrile  must  be  allowed  to  drink  freely,  and 
to  choose  for  drinking  what  they  like  (water,  wine-and- 
water,  tea,  coffee,  milk,  toast-water,  syrup  and  water,  or 
fruit-juice  in  water).  The  temperature  of  the  drink  must 
vary  according  to  the  patient's  state  (that  is,  when  fever 
is  high,  the  drink  must  be  cold ;  otherwise  the  patient 
may  drink  what  he  likes  at  the  ordinary  temperature). 
As  regards  the  temperature  of  the  air  in  which  the  patient 
breathes,  the  author  comes  to  the  conclusion  that  it  must 
oscillate  between  56°  and  63°  F.,  not  exceeding  the  latter 
limit.  The  necessity  of  most  carefully  maintaining  the 
purity  of  the  air  in  the  patient's  room  is  placed  by  the 
author  on  a  level  with  the  necessity  of  good  feeding. 
Passing  to  the  last,  but  not  the  least,  point  of  his  article, 
the  author  substantiates  his  demand  for  the  greatest 
possible  amount  of  rest  for  the  febrile.  Having  pointed 
out  the  well-known  data  referring  to  the  influence  of 
muscular  work  on  various  systemic  functions,  the  author 
mentions  his  own  experiments  on  the  healthy,  tending  to 
prove  that  moving  about  leads  to  an  increase  of  from 
four  to  eighteen  per  cent  in  the  excretion  of  nitrogen 
in  urine ;  most  probably  the  influence  of  movement  on 
nitrogenous  metamorphosis  in  the  febrile  subjects  must 
be  still  more  powerful. 

Gastrostomy,  CEsophagostomy,  and  other  Opera- 
tions FOR  THE  Relief  of  Stricture  of  the  CEsopha- 
Gus. — The  frequency  of  carcinomatous  obstruction  of 
the  oesophagus  in  middle  life,  and  of  cicatricial  or 
fibrous  stricture,  particularly  in  subjects  of  tender  years, 
has  led  Dr.  S.  W.  Gross  to  collect,  in  the  July  number 
of  The  American  Journal  of  the  Medical  Sciences^  the 
somewhat  numerous  and  scattered  instances  of  the 
various  operations  which  have  been  practised  for  their 
relief,  and  study  and  compare  their  relative  value  and 
disadvantages.  To  fulfil  thb  object  intelligently  he  has 
considered  separately  carcinomatous  and  simple  strict- 
ures. The  four  operations  applicable  to  carcinomatous 
stricture  are  gastrostomy,  oesophagostomy,  internal  cesoph* 
agotomy,  and  oesophagectomy,  of  which  the  first  three 
are  palliative  and  the  last  curative.  From  the  considera- 
tion of  one  hundred  and  ninety-four  cases  of  opera- 
tive procedure.  Dr.  Gross  finds  that  gastrostomy  has 
proved  to  be  the  simplest,  most  rational,  and  safest 
of  the  four  operations  for  the  relief  of  carcinomatous 
stricture.  Increasing  experience  demonstrates  that 
the  results  are  growing  better  and  better,  which  can- 
not be  said  of  oesophagostomy;  and  there  is  every 
reason  to  believe  that  the  successes  will  become  more 
numerous  if  it  is  resorted  to  as  soon  as  the  diagnosis 
of  the  disease  has  been  made,  and  before  the  powers 
of  the  patient  are  materially  impaired.  The  few  deaths 
do  not  constitute  an  argument  against  its  adoption ; 
while  "  every  recovery  is  a  clear  gain,  and  a  fatal  issue 
is  simply  the  natural  termination  forestalled."  The 
operations  which  have  been  practised  for  cicatricial 
stricture  are  gastrostomy,  oesophagostomy,  internal  oesoph- 
agotomy,  combined  oesophagotomy,  and  retrograde  di- 


96 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


vulsion.  Dilatation,  Dr.  Gross  holds,  is  merely  a  pal- 
liative remedy,  and  sufficient  time  has  not  yet  elapsed  to 
test  the  value  of  divulsion  through  an  opening  in  the 
stomach.  Combined  oesophagotomy  for  strictures  near 
the  cardia  is  only  applicable  to  children,  and  may  prove 
of  value  in  strictures  impassable  by  instruments  intro- 
duced through  the  mouth.  Internal  oesophagotomy,  if 
performed  at  all,  should  be  reserved  for  comparatively 
recent  and  short  strictures,  and  oesophagostomy  is  only 
applicable  when  the  incision  can  be  made  below  the  ob- 
struction. Gastrostomy,  he  holds,  is  the  best  and  safest 
operation  for  simple  stricture  of  the  oesophagus.  From 
the  great  difficulty  of  managing  cicatricial  stricture 
in  children  by  dilatation,  which  is  due  partly  to  the 
struggles  of  the  subjects  and  partly  to  the  disinclination 
of  the  parents  to  distress  the  child,  Dr.  Gross  holds  that 
dilatation  should  be  resorted  to  only  when  the  inflamma- 
tion has  subsided  and  the  denuded  surface  is  in  a  granu- 
lating condition.  When  the  constriction  is  of  some 
standing,  and  efforts  at  dilatation  prove  fruitless,  gastros- 
tomy will  prove  to  be  the  safest  and  most  beneficial 
operation  for  prolonging  life. 

Theories  of  Color-perception.  —  Dr.  Swan  M. 
Burnett,  of  Washington,  D.  C,  discusses  the  various 
theories  of  color-perception,  and  points  out  that  none  of 
them  accounts,  in  a  consistent  manner,  for  all  the  phe- 
nomena of  normal  and  abnormal  colored  vision,  and 
that,  moreover,  there  are  certain  objections  on  physical 
grounds  which,  with  our  present  knowledge  of  the  laws 
of  molecular  and  wave-motion,  are  insurmountable. 
He  advances  a  theory  which,  he  thinks,  meets  the  require- 
ments of  the  case  in  the  light  of  recently  acquired 
knowledge.  He  holds  that  it  is  essential  to  do  away 
with  the  idea  of  the  retina  as  a  differentiating  organ,  and 
that  it  should  be  looked  upon  simply  as  receiving  and 
transmitting  structure  which  shall  give  up  faithfully  to  the 
optic  nerve  the  impressions  made  upon  it  by  the  waves 
of  the  luminiferous  ether.  These  impressions  are  carried 
by  the  nerve  to  the  brain,  and  are  there  properly  differ- 
entiated and  converted  into  sensations.  He  believes 
that  by  this  means  ail  the  phenomena  of  color-perception 
and  color-blindness  can  be  explained  in  a  natural  and 
consistent  manner  without  the  necessity  of  imagining  new 
tissues,  or  novel  or  unusual  reactions  of  these  tissues  to 
light.  Dr.  Burnett  considers  the  retina  to  be  a  sub- 
stance whose  ultimate  structure  is  such  as  to  allow  it  to 
respond  at  one  and  at  the  same  time  to  a  large  number 
of  ethereal  vibrations ;  at  least  such  a  number  as  shall 
be  represented  by  the  clearly  distinguishable  colors  of 
the  spectrum. — American  Journal  of  the  Medical 
Sciences y  July,  1884- 

A  Case  of  Tubal  Pregnancy. — Dr.  Henry  Hun,  of 
Albany,  records,  in  The  American  Journal  of  the  Medical 
Sciences  for  July,  1884,  a  case  of  tubal  pregnancy,  in 
which  the  cyst  burst  at  about  the  twenty-fifth  day,  and 
the  patient  died.  Dr.  Hun  obtained  the  specimen,  and 
after  having  rendered  the  embryo  transparent  by  oil  of 
cloves,  carefully  studied  it  and  made  an  accurate  drawing 
of  it.  In  this  case  the  ovum  was  in  the  right  Fallopian 
tube  and  its  corpus  luteum  was  in  the  left  ovary.  In  a 
considerable  number  of  cases  of  tubal  pregnancy  the  cor- 
pus luteum  is  found  in  the  ovary  of  the  other  side,  and  it 
is  very  possible  that  this  unusual  origin  of  the  ovum  may 
be  the  cause  of  the  tubal  pregnancy,  for  if  the  tube  bends 
over  and  reaches  the  opposite  ovary  it  will  be  apt  to  be 
so  bent  and  twisted  that  the  ovum  will  meet  with  great 
difficulty  in  passing  through  it,  or,  if  an  impregnated 
ovum  passes  across  the  pelvis  and  enters  the  tube  of 
the  other  side,  so  much  time  will  be  consumed  in  its 
journey  that  it  may  develop  to  such  a  size  before  it  gets 
to  the  uterus  that  it  cannot  pass  through  the  tube,  and 
will  continue  its  development  in  this  organ.  This  is  the 
only  cause  which  can  be  assumed  in  Dr.  Hun's  case,  for 
there  was  no  occlusion  of  the  tube  by  tumors,  bands  of 
adhesions,  or  displacement  of  the  uterus,  as  are  some- 


times found  in  these  cases ;  neither  was  there  any  great 
fright  or  emotion  experienced  at  or  near  the  time  of 
sexual  intercourse,  which,  in  a  number  of  such  cases,  has 
appeared  to  cause  the  extra-uterine  pregnancy. 

Unilateral  Swelling  of  Hysterical  Hemiplegia.— 
Dr.  S.  Weir  Mitchell  records,  in  the  July  number  of  The 
American  Journal  of  the  Medical  Sciences,  three  cases 
of  hysteria,  in  which  there  was  unilateral  increase  in 
bulk  at  or  near  the  menstrual  period,  and  also  at  other 
seasons,  after  emotional  excitement,  and  he  has  been 
unable  to  find  elsewhere  any  narration  of  similar  cases. 
Whatever  conclusions  we  may  reach  as  to  the  immediate 
cause  of  the  unilateral   differences  in  size,  which  Dr. 
Mitchell  has  here  described,  it  is  at  least  clear  that  they 
are  under  the  influence  of  the  nervous  system,  and  vary 
with  the  causes  which  also  increase  or  lessen  the  anal- 
gesia,  or  give  rise  to  chronic  spasm.     Beyond  tlus  Dr. 
Mitchell  can  as  yet  hardly  go.     Most  probably,  he  thinks, 
it  will  be  found  that  in  many  unilateral  hysteric  palsin  a 
like  phenomenon  exists,  and  has  merely  eBcapeid  xtteo- 
tion  because  of  being  the  least  prominent  in  a  group  oC 
symptoms.     At  all  events,  it  adds  another  to  the  large 
group  of  resemblances  which  so  closely  relate  organic 
to  hysteric  hemipalsy. 

Treatment  of  Ingrowing  Toe-nail. — Professor  Pe- 
tersen removes  the  whole  of  the  soft  parts  down  one 
side  of  the  nail,  extirpates  the  nail  itself,  from  antiseptic 
motives,  and,  aiter  arresting  bleeding  by  pressure,  dresses 
the  wound  rapidly  with  oxide  of  zinc  and  cotton-wool. 
Fourteen  days'  rest  in  bed,  with  the  foot  raiaed,  generally 
suffices  for  cure,  and  the  contraction  of  the  cicatrix  pre- 
vents a  relapse  to  the  old  condition.  Professor  Petersen 
prefers  general  to  local  anaesthesia,  on  account  of  the 
troublesome  bleeding  afterward ;  and  for  the  same  rea- 
son he  does  not  approve  of  Esmarch^s  bandage  in  this 
operation.— Ci«.  Lancet  and  Clinic^  June  14,  1884. 

Massage  in  the  Treatment  of  Stricture  of  the 
Urethra. — The  difficulty  of  passing  a  sound  in  stricture 
of  the   urethra  following  gonorrhoea  depends,    in    the 
majority  of  cases,  not  so  much  upon  the  simple  narrovring 
of  the  urethra  itself  as  upon  proliferation  of  the  connec- 
tive tissue  in  the  surrounding  parts.     This  hyperplasia  of 
the  connective  tissue  occurs  in  irregular  patches  about 
the  urethra  in  such  a  way  as  to  render  the  canal  tortuous, 
thus  increasing  the  difficulty  of  passing  an  instrument  to 
the  bladder.      Dr.  G^za  v.  Antal  relates  a  number  of 
cases  {Centralblatt  fur  Chirurgie,  June  7,  1884)  in  which 
he  succeeded  in  inducing  absorption  of  this  hyperplasia 
by  massage.     The  duration  of  each  sitting  was  from  eight 
to  ten  minutes,  and  the  massage   was  repeated   da^y. 
Massage  of  the  pendulous  portion  of  the  urethra  presents 
no  difficulties,  but  that  of  the  membranous  and  prostatic 
portions  is  possible  only  through  the  rectum.      Internal 
massage  by  means  of  the  repeated  introduction  and  with- 
drawal of  a  sound,  as  recommended  by  Bardinet,  does 
not  commend  itself  to  the  author.     It  is  only  possible  in 
those  cases  in  which  the  stricture  is  already  permeable, 
while  V.  An  tar  s  method  is  of  especial  value  precisely  in 
those  cases  in  which  the  urethra  will  not   admit  of  the 
passage  of  a  bougie.     Further  than  this,  internal  massage 
acts  only  upon  the  thin  layer  of  tissue  immediately  sur- 
rounding the  urethra,  while  the  external  method  causes 
the  entire  hyperplasia  to  disappear.     The  author  thinks 
that  in  many  cases  massage  will  be  used  in  preference  to 
urethrotomy. 

Rabies  in  Birds. — M.  L.  Gibier  has  succeeded  in  in- 
oculating hens  with  the  virus  of  hydrophobia  and  the;i 
reinoculating  rats  with  cerebral  matter  taken  from  these 
diseased  birds.  The  rats  so  treated  presented  all  the 
characteristic  symptoms  ot  rabies ;  microscopic  exami- 
nation of  the  brains  of  the  inoculated  hens  showed  the 
presence  of  the  specific  micrococcus. — Centralblatt  fOr 
Chirurgie^  June  7,  1884. 


July  26,  1884.J 


THE  MEDICAL  RECORD. 


97 


Death  following  the  Extraction  of  a  Tooth. — 
Pr.  Zakharevitch  relates  two  instances  of  young  men, 
both  physicians,  dying  from  the  results  of  the  extraction 
of  a  molar  tooth.     One  died  ten  days  after  the  operation 
fiK)iD  osteomyelitis,  and  the  other  six  days  after  from 
osteitis  of  the  inferior  maxilla  and  septicaemia.     It  was 
found  that  the  dentist  had  not  been  careful  in  cleaning 
the  forceps  used  by  him.     The  author,  moved  by  these 
accidents,  recommends  the   employment   of  antiseptic 
tooth-pulh'ng.     He  advises   washing  the   inside   of  the 
checks  with  soap  and  water,  and  then  with  a  two  per  cent, 
solution  of  carbolic  acid.     After  the  tooth  has  been  ex- 
tracted the  mouth  should  be  again  washed  with  the  car- 
boiic  solution  and  the  tooth  cavity  filled  with  a  wad  of 
cotton  charged    with    iodoform   powder. — Raccoglitore 
Medico,  June  20,  1884. 

Treatment  of  Slight  Burns. — Dr.  Cramer  treats 
sl^bt  degrees  of  burns  by  means  of  compression.  He 
applies  a  layer  of  wadding  and  over  this  an  elastic  band- 
age, so  as  to  make  firm  and  even  pressure  over  the  whole 
of  die  injured  surface.  By  this  means  the  subcutaneous 
capillaries  are  emptied  in  a  measure  of  their  blood,  and 
iD^ammation  and  exudation  of  serum  are  prevented. 
The  compression  is  to  be  maintained  from  three  to  fifteen 
hours,  according  to  the  intensity  of  the  bum,  and  then  a 
less  degree  of  pressure  kept  up  until  new  epidermis  has 
ixxm^.'-Memoriibilien,  May  14,  1884. 

Treatment  of  Sweating  of  the  Feet. — The  follow- 
ing method  of  treatment  for  this  unpleasant  condition  is 
endorsed  by  Dr.  G.  Cramer  in  Memarabilien  of  May  14, 
1884.  The  patient  must  wash  his  feet  thoroughly  in  a  two 
to  five  per  cent  solution  of  carbolic  acid,  at  first  twice  a 
day,  then  once  a  day,  and  finally  two  or  three  times  a 
veek.  After  the  bath  he  is  to  put  on  clean  stockings, 
sprinkled  inside  and  outside  with  a  powder  composed  of 
two  parts  benzoin,  three  parts  salicylic  acid,  and  ninety-five 
parts  magnesia.  The  shoes  must  also  be  sprinkled  inside 
with  the  powder.  The  stockings,  when  Uken  off,  should 
be  allowed  to  soak  for  twelve  hours  in  carbolized  water, 
then  dipped  in  lye,  and  washed.  In  this  way  the  bac- 
teria which  cause  the  skin  affection  and  the  consequent 
atnormal  secretion  of  sweat  are  destroyed  Without 
thb  thorough  disinfection.  Dr.  Cramer  maintains,  a  cure 
of  the  affection  is  impossible. 

The  Apyretic  Form  of  Typhoid  Fever. — Dr. 
Brothier  has  collected  several  observations,  which  show 
that  in  certain  cases  the  characteristic  lesions  of  typhoid 
fever  may  be  found  in  patients  whose  temperature  has 
always  remained  normal.  In  spite  of  the  apparent  mild- 
ness of  the  disease,  hemorrhages,  perforation,  and  other 
comfdications  are  liable  to  occur.  The  symptoms  are 
those  of  the  ordinary  form,  with  the  exception  that  they 
are  less  marked,  and  that  the  temperature  does  not  rise 
above  the  normal  standard.  It  is  very  important  to 
keep  the  patient  in  bed,  and  the  diet  must  be  carefully 
legolated.— y^^^r.  de  M/d.  €t  de  Chir.  Prat 

Reunion  of  Divided  Nerves. — Nerve-suture  is  often 
aosuccessful,  especially  in  those  cases  in  which  a  portion 
of  die  nerve  has  been  excised,  the  tension  causing  the 
wtures  to  cut  their  way  out.  For  this  reason  Dr.  A.  L. 
l^s^^]L\eS{C€ntraidlattfiir  Chirurgie,  June  7,  1884), 
has  discarded  this  method,  and  instead  simply  brings  the 
<firided  ends  of  the  nerve  so  that  they  overlap,  and  then 
tes  diem  together.  He  has  found  by  experiments  upon 
more  than  a  hundred  animals  that  the  conductive  power 
<if  the  nerve  is  perfectly  restored.  After  exposing  the 
Bcrve-sheath,  an^  before  dividing  it,  he  passes  two  catgut 
hgatures  beneath  it,  and  ties  them  tightly  enough  to  pre- 
vent slipping.  The  nerve  is  then  divided,  ana  the  two 
«ds,  after  flexing  the  limb  so  that  they  may  overlap,  are 
W  together,  ^er  the  expiration  of  from  six  to  twenty 
ooDdis,  experiments  were  made  to  test  the  conductivity 
of  the  nerves,  and  in  every  case  the  muscles  responded 


readily  to  central  irritation  of  the  nerves.  In  some  cases 
he  divided  two  nerves  and  reunited  them  in  crossed 
fashion,  so  that  the  peripheral  end  of  one  nerve  was  at- 
tached to  the  central  extremity  of  the  other.  Then,  after 
allowing  sufficient  time  to  elapse  for  union  to  occur,  he 
found  that  central  irritation  of  one  nerve  was  followed 
by  a  response  in  the  muscles  attached  to  the  peripheral 
extremity  of  the  other  nerve  with  which  the  first  had  been 
united.  This  was  conclusive  proof  that  union  between 
the  two  divided  nerves  was  perfect  The  author  believes 
that  his  method  will  be  found  of  especial  utility  in  those 
cases  of  gunshot  wounds  and  the  like  in  which  there  has 
been  a  considerable  loss  of  nerve-substance,  and  which 
are  precisely  the  cases  where  suture  of  the  divided  ends 
is  impracticable.  In  operations  also  in  which  a  number 
of  nerves  or  a  plexus  has  been  divided,  the  various  ends 
may  be  tied  together  without  regard  to  preserving  their 
separate  identity,  in  the  expectation  that  the  functions  of 
all  the  wounded  nerves  will  be  restored. 

Miliary  Aneurisms  of  the  Mucous  Membrane  of 
the  Stomach. — Dr.  Gallard  reports  {^Gaz,  Hebdoma- 
daire)  the  case  of  a  man,  forty-eight  years  of  age,  who 
was  admitted  into  the  hospital  in  a  state  of  extreme 
prostration,  caused  by  repeated  hemorrhages  from  the 
stomach.  There  was  anorexia,  and  pain  in  the  epigastric 
region,  but  no  local  or  general  disease  could  be  made 
out  The  patient  died  after  a  few  hours,  and  at  the  post- 
mortem examination  an  aneurism  of  the  size  of  a  bean, 
situated  near  the  cardia,  was  found  to  have  given  way. 
Gallard  has  observed  two  other  cases  of  the  same  affec- 
tion, and  thinks  that  the  so-called  essential  hsematemesis 
is  generally  caused  by  the  rupture  of  a  small  gastric 
aneurism. 

Left  Inguinal  Colotomy  for  Imperforate  Rec- 
tum.— Dr.  W.  H.  Haynes,  of  New  York,  records  in  the 
July  number  of  The  American  Journal  of  the  MediccU 
Sciences  a  case  of  inguinal  colotomy.  One  procedure  in 
the  treatment  we  do  not  find  discussed  elsewhere  in 
detail,  namely,  that  of  opening  up  a  passage  at  the 
natural  site  for  the  canal,  either  simultaneously  or  sub- 
sequent to  the  operation  of  opening  the  gut  When  the 
two  operations  are  to  be  performed  at  the  same  time, 
the  first  or  inguinal  opening  would  be  in  the  nature  of 
an  exploratory  operation,  and  should  be  made  small  so 
as  to  admit  of  immediate  closure,  and  return  to  the 
peritoneal  cavity  after  a  passage  had  been  secured  2^  the 
natural  site.  If  this  latter  be  not  secured,  then  the 
opening  could  be  enlarged  and  made  to  serve  the  pur- 
pose of  an  artificial  anus  in  the  abdominal  wall.  The 
advisability  of  this  procedure,  however,  is  at  present  in 
such  a  doubtful  state  that  only  the  experience  of  a 
number  of  operators  can  determine  it  Of  the  few  cases 
so  far  undertaken  in  this  manner  that  Dr.  Ha^^nes  can 
find  recorded,  his  own  is  the  only  one  that  survived  the 
second  operation.  Dr.  Haynes'  single  experience,  though 
successful,  does  not  lead  him  to  advise  this  procedure, 
since  the  object  of  it  will,  during  the  early  years  of  its 
life,  be  dependent  on  the  exceedingly  diligent  and  con- 
stant attentions  of  others  whose  affections  and  services, 
though  the  closest,  are  not  to  be  depended  on,  as  was 
demonstrated  in  his  case.  If  the  second  operation  be 
subsequent  to  the  first,  the  patient  will  have  a  double 
annoyance,  or  be  under  the  necessity  of  having  a  third 
operation  performed  for  the  closure  of  the  opening  first 
made,  which  is  not  unattended  by  danger  to  life  or  of 
doubts  as  to  the  result;  and  perhaps  be  under  the 
necessity  of  having  to  have  it  reopened,  owing  to  neglect 
in  the  proper  after-treatment  of  the  new  canal  in  the 
natural  site.  Whereas  if  one  is  satisfied  with  having 
saved  life  in  a  manner  which  numerous  cases  testify  is 
not  unenjoyable  or  full  of  discomfort,  as  used  to  be 
maintained,  all  dangerous  risks  of  subsequent  operations 
are  avoided,  there  will  be  no  more  dependence  on  others' 
services  than  is  natural,  and  many  sources  of  distress 
will  be  obviated. 


98 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


The  Medical  Record: 


A  Weekly  Journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &.  Co.,   Nos.  56  and  58  Lafayette  Place. 

New  York,  July  26,  1884. 

CHOLERA  AND  THE  CABINET. 

The  approach  of  cholera  along  the  great  routes  of  Euro- 
pean emigration  to  the  Northern  ports,  and  the  ever- 
threatening  presence  of  yellow  fever  along  the  lines  of 
commercial  intercourse  between  tropical  countries  and 
the  Southern  ports,  places  the  United  States  this  season  in 
a  peculiarly  dangerous  position  with  reference  to  those 
foreign  pestilential  diseases.  So  eminent  an  authority  as 
Koch  is  reported  to  have  stated,  after  personal  exami- 
nation of  cases  at  Toulon,  that  the  disease  is  genuine 
Asiatic  cholera,  and  of  the  most  unmanageable  type,  and 
that  it  would  spread  everywhere.  This  statement  is  in 
Accordance  with  our  own  convictions,  as  stated  in  a 
previous  article,  in  which  we  took  occasion  to  urge  our 
health  authorities,  and  especially  those  of  the  large  sea- 
port towns  whither  emigration  tends,  to  take  immediate 
steps  both  to  effect  thorough  sanitation  and  to  vigilantly 
watch  the  current  diarrhoeal  affections.  As  to  yellow 
fever,  no  predictions  can  be  made ;  it  is  a  summer 
pestilence  which  is  ever  at  our  doors,  and  only  awaits 
favoring  conditions  to  invade  our  Southern  seaboard 
cities.  Of  this,  however,  we  are  reasonably  certainy 
viz. :  that  the  United  States  is  threatened  with  two 
foreign  foes,  the  most  fotal  to  public  health  and  national 
prosperity  of  any  known,  both  of  which  it  is  in  the  power 
of  a  properly  organized  and  equipped  sanitary  service  to 
prevent  The  progress  of  cholera  since  our  last  article 
confirms  our  prediction  that  we  are  imminently  threat- 
ened with  an  outbreak  of  this  Oriental  plague,  and  we 
urgently  advise  all  local  boards  of  health  to  organize 
their  methods  and  forces  as  if  in  the  very  presence  of  the 
epidemic.  We  repeat  what  we  then  said,  and  with  added 
emphasis,  that  no  intelligent  health  authority  will  rely  on 
our  present  quarantines  to  prevent  the  introduction  of 
the  germs  of  that  disease  into  this  country.  If  the  epi- 
demic is  rendered  in  any  sense  harmless,  and  is  brought 
under  any  proper  control,  it  will  be  by  the  vigorous  and 
vigilant  action  of  local  boards  of  health.  We  are  grati- 
fied to  notice  that  the  New  York  State  Board  has  issued 
the  excellent  memoranda  prepared  by  its  late  Secretary, 
Dr.  Elisha  Harris,  and  that  other  State  Boards  have 
taken  similar  action. 

In  this  approaching  conflict  with  a  foreign  foe,  more 
dangerous  to  the  health  and  prosperity  of  the  people  than 
a  European  army,  it  is  pertinent  to  inquire  what  is  the 
attitude  of  our  Government  toward  this  national  scourge  ? 
With  the  first  rumor  of  cholera  in  Toulon,  the  Govern- 


ments of  Europe  summoned  their  Boards  of  Healdi  to 
prepare  regulations  and  to  take  immediate  measures  to 
prevent  an  invasion  of  the  epidemic.  Among  those 
brought  into  the  service  of  their  respective  States,  we  no- 
tice the  names  of  the  eminent  sanitarians  Koch  and  Pas- 
teur, of  Brouardel  and  Prouse,  of  Buchanan  and  Car- 
penter. But  what  action  has  our  Government  taken  to 
protect  the  country  now  on  the  eve  of  invasion  by  two 
of  the  most  terrible  scourges  known  to  the  human  £unily  ? 
Though  it  has  in  its  service  a  National  Board  of  Health, 
composed  of  experienced  physicians  and  sanitary  experts, 
the  duty  of  which  is,  according  to  the  statute,  "  to  obtain 
information  upon  all  matters  affecting  the  public  health, 
to  advise  the  several  departments  of  the  Government 
.  .  .  on  all  questions  submitted  by  them,"  we  cannot 
learn  that  the  advice  of  this  Board  has  been  sought  in 
this  great  and  pressing  emergency,  on  any  question  relat- 
ing to  the  approaching  epidemics,  by  any  department  of 
Government.  It  appears  that  the  Cabinet  had  a  meet- 
ing ;on  Saturday,  and  '*it  was  decided  to  take  prompt 
measures  to  prevent  the  introduction  of  cholera  into  the 
United  States  ;  the  State  and  Treasury  Departments  will 
act  in  conjunction  in  enforcing  the  regulations  to  be  pre- 
pared." What  member  of  the  Cabinet  is  sufficiently 
familiar  with  the  latest  discoveries  of  science  and  the 
teachings  of  experience  in  the  control  of  cholera  to  pre- 
pare these  "regulations,"  does  not  appear.  In  the  Cab- 
inets of  Europe  no  one  has  been  found  competent  to 
prepare  "  regulations  "  to  meet  the  demands  of  modem 
science  in  Uie  prevention  of  cholera,  and  hence  those 
Governments  at  once  called  to  their  aid  their  several 
National  Boards  of  Health,  and  submitted  to  them  all 
questions  relating  to  the  prevention  of  the  epidemic. 
But  with  an  assurance  peculiar  to  the  Yankee  nation,  our 
Cabinet  ignores  the  branch  of  the  public  service  consti- 
tuted by  law  its  adviser  on  all  matters  pertaining  to  the 
public  health,  and  single-handed  grapples  with  and  setties, 
to  its  own  satisfaction,  questions  of  science  which  the 
foremost  medical  men  approach  with  special  care  and 
caution.  If  we  may  judge  of  the  character  of  the  "  regu- 
lations" in  course  of  preparation  by  the  daily  bulletins 
from  the  Capitol,  or  from  the  President's  Proclamation, 
we  should  infer  that  the  Cabinet  had  consulted  some  an- 
tiquated authority — a  resident  of  Venice  in  the  fifteenth 
century.  As  yet  the  Government  has  proposed  no 
measure  at  all  adequate  to  the  emergency,  and  is  evi- 
dently entirely  unaware  of  its  duties  and  its  obligations. 
Its  reliance  seems  to  be  on  daily  bulletins  issued  to  the 
Associated  Press  and  a  proclamation  by  the  President 

Well-meaning  as  undoubtedly  these  efforts  of  the 
Cabinet  are,  we  venture  to  suggest  that  they  are  alto- 
gether unworthy  the  age  and  the  occasion.  If  no  better 
counsels  prevail  in  the  Cabinet,  cholera  will  invade  our 
shores  and  spread  far  and  wide,  except  as  it  is  stamped 
out  in  localities  by  energetic  and  enlightened  boards  of 
health,  and  the  money  appropriated  by  Congress  will 
melt  away,  leaving  no  record  of  great  achievements  in 
the  prevention  of  the  epidemic. 

We  make  these  remarks  in  no  captious  or  cavilling 
spirit,  but  with  a  painful  consciousness  that  in  the  strug- 
gle among  nations  to  combat  this  common  foe  of  the 
human  race,  our  Government  lags  far  behind.  It  enters 
upon  a  warfare  discarding  the  very  arm  of  the  public 


July  26,  1884.] 


THE  MEDICAL  RECORD. 


99 


service  created  for  the  occasion,  and  fully  qualified  to 
give  k  the  highest  degree  of  success  in  the  field  of  con- 
flict   Much  as  we  lament  the  occurrence  of  a  great 
epidemic,  which  leaves  only  misery,  ruin,  and  death  in 
its  path,  we  still  recognize  the  fact  that  every  such  de- 
vastation brings  us  nearer  to  the  golden  era  when  no 
contagious  or  infectious  disease  will  be  allowed  to  travel 
along  the  highways  of  commerce  and  human  intercourse. 
The  yellow  fever  epidemic  of  1878  was  a  national  calam- 
ity, but  it  did  more  to  organize  a  system  of  sanitary  ser- 
vice in  this  country  than  would  a  century  of  agitation 
by  simple  agreements  and  appeals.     Six  years  of  free- 
dom  from  epidemics  has  created  an  indifference  to  health 
oiganizations  which  has,  in  many  instances,  ripened  into 
actual  hostility  to  their  existence.     It  requires  other 
great  epidemics  to  restore  these  organizations  to  the 
public  confidence  and  perfect  their  methods  of  work. 
That  these  epidemics  will  come,  as  great  public  educa- 
tors, at  proper  intervals,  until  our  system  of  sanitary 
government  is  perfected,  we  need  not  doubt.     We  look 
hopefully  forward  to  the  time  when   sanitary  science, 
thoroughly  and  intelligently  applied  by  national.  State, 
and  municipal  governments,   will   eliminate   from   our 
mortality  records  the  names  of  all  contagious  and  infec- 
tious diseases. 


THE  TREATMENT  OF  DIARRHCEA. 
A  CONSIDSRATION  of  thc  commonest  diseases  acquires  a 
special  interest  at  different  times.     At  present  as  we 
arc  in  the  midst  of  the  heated  season,  with  cholera  just 
on  the  edge  of  the  horizon,  it.may  be  of  interest  to  dis- 
cuss such  a  fiamihar  subject  as  the  treatment  of  diar- 
ihoea.    AU  recognize  that  a  diarrhoea  is  simply  an  ex- 
pression of  a  certain  derangement  of  the  gastro-intestinal 
tract    To  interpret  and  remove  [the  cause  should  be 
the  first  rational  effort  of  treatment     Now  as  the  vast 
majority  of  gastro-intestinal  disturbances  are  produced 
by  indigestible  food,  a  diarrhoea  is  very  frequently  at  the 
start  a  conservative  process  induced  by  nature  to  get  rid 
of  such  an  offending  mass.     In  the  efforts  to  achieve  this 
object  a  catarrhal  inflammation  is  often  set  up.     The 
idea  of  treatment  should  be  to  so  expedite  the  removal 
of  the  foreign  substance  as  to  save  the  intense  irritation 
inTolved  in  nature's  unaided  efforts  to  accomplish  this 
end    In  these  days,  lobsters  and  green  apples,  clams 
and  cucumbers,  are  among  us.     Their  digestion  is  fre- 
quently assisted  by  ice-cream ;  nearly  always  by  large 
quantities  of  ice-water.     Just  as  the  unfortunate  stomach 
is  trying  to  get  warmed  up  to  its  difficult  task,  its  tem- 
perature is  suddenly  and  gready  lowered  by  a  deluge  of 
ice-water.     This  is  repeated  so  frequently  that  finally 
the  injured  viscus  gives  up  in  despair  and  passes  the 
mcfaanged  material  along  to  the  intestine  to  get  rid  of 
it  as  best  it  may.     It  is  fortunate  for  the  patient  if  the 
doctor,  m  his  zeal  to  check  the  naturally  induced  pxurg- 
ing,  does  not  suddenly  lock  up  the  bowel,  and  in  it  the 
offending  master  that  is  causing  all  the  trouble.     There 
is  a  popular  idea  that  a  diarrhoea  should  not  be  stopped 
too  saddenly.     As  there  is  nearly  always  a  grain  of  truth 
someiHiere  to  be  found  underlyin^^  a  popular  delusion, 
10  this  idea  doubtless  rests  upon  the  fact  that  an  intes- 
ttBal  discharge  due  to  irritating  masses  of  food,  suddenly 
^faeded  by  a  heroic  dose  of  opium,  may  be  followed  by 


inflammation  of  the  bowels  and  peritonitis.  When  such 
a  source  of  irritation  has  been  removed,  a  diarrhoea  can- 
not be  checked  too  quickly.  Indeed,  fxurther  treatment 
is  frequently  unnecessary.  The  elimination  of  indigest-' 
ible  substances  can  be  accomplished  by  various  agents. 
All  irritating  laxatives  must  be  avoided  A  few  grains 
of  calomel  finely  triturated  with  a  litde  bicarbonate  of 
soda  and  sugar  of  milk  often  does  very  well.  A  small 
dose  of  calomel  if  triturated  finely  enough,  will  answer  all 
the  purposes  of  a  large  amount.  Many  physicians  prefer 
castor-oil  or  some  of  the  preparations  of  rhubarb  for 
cleaning  out  the  bowel.  The  secondary  astringent  effects 
of  these  drugs  are  beneficial  It  is  well  to  combine  with 
them  a  small  quantity  of  one  of  the  preparations  of 
opium.  After  the  irritating  cause  of  a  diarrhoea  has 
been  removed,  the  different  astringents  can  be  used, 
according  to  the  preference  of  the  practitioner.  Out  of 
a  very  large  number  from  which  to  choose,  the  sub-nitrate 
of  bismuth  in  large  doses  is  probably  the  least  harmful 
and  most  effectual.  It  checks  any  acid  fermentation, 
and  soothes  and  constringes  the  mucous  membrane. 

While  improper  food  is  a  preponderating    element 
in  the  diarrhoea  of  summer,  impure  water  and  foul  air 
introduce  into  the  system  noxious  ingredients  that  are 
frequently  irritating  to  the  bowel.     It  is  a  common  ex- 
perience of  medical  students  to  contract  a  diarrhoea  from 
staying  in  the  dissecting-room,  which  ceases  when  they 
stop  working  upon  the  cadaver.     A  conservative  process 
of  elimination  is  here  instituted  that  probably  saves  them 
a  fever.     Animal  and   vegetable  refuse  matter  in  the 
streets,  wakened  into  active  fermentadon  by  the  hot  sun 
of  summer,  may  act  the  same  upon  the  layman  as  the 
dissecting-room  does  upon  the  students.     Some  persons 
seem  to  be  peculiarly  susceptible  to  this  form  of  poison, 
and  correspondingly  quick  to  throw  it  off  by  a  diarrhcear 
The  treatment  of  this  form  of  intestinal  derangement  is 
obviously  to  remove  the  patient  from  exposure  to  the 
foul  air,  .when  recovery  will  readily  take  place.     Mild 
astringents  may  be  needed  to  hasten  this  result.    Occa- 
sionally persons  in  debilitated  condition,  in  consequence 
of  the  heat  and  impurity  of  air  so  frequently  found  in  the 
city  in  summer,  seek  to  relieve  a  continual  irritation  of 
the  bowels  by  a  change  to  the  purer  air  of  the  country. 
But  if  the  air  is  purer,  unfortunately  often  as  much  can* 
not  be  said  of  country  water.     In  fact,  many  people 
leaving  town  in  a  sound  condition  fall  victims  to  diarrhoea 
before  many  days'  sojourn  in  the  country.     The  uncom- 
fortable proximity  of  the  cess-pool  to  the  well,  and  the 
defective  means  of    ridding  the  premises  of   sewage, 
destroy  the  good  effects  of  many  a  rural  visit     The 
sanitary  condition  of  numbers  of  farm-houses  and  country 
hotels  is  far  from  what  it  should  be.     If  the  visitor  does 
no  more  than  contract  a  diarrhoea  in  many  of  these 
places  he  will  be  fortunate.     Of  course  a  simple  change 
in  the  character  of  drinking  water  often  produces  a  slight 
diarrhoea,  aside  from  any  animal  or  excess  of  vegetable 
matter  it  may  contain.     If  a  looseness  of  the  bowels  per- 
sists,  however,  after  treatment  by  ordinary  astringents, 
the  patient  had  better  quickly  change  his  place  of  sum- 
mer recreation.    The  valuable  account  of  the  sanitary 
condition  of  health  resorts,  appearing  in  the  report  of 
the  National  Board  of  Health  for  1882,  affords  interest- 
ing reading  on  this  subject. 


lOO 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


We  have  thus  seen  that  a  diarrhoea  is  primarily  a  conser- 
vative process  of  nature  indicating  its  eflforts  to  eliminate 
some  disturbing  element  in  the  economy,  and  that  during 
the  present  season;  indigestible  food,  bad  air,  and  impure 
water,  under  the  debilitating  influences  of  high  tempera- 
ture, are  most  frequent  causes  in  its  production.  Any 
looseness  of  the  bowels  must  always  be  treated  directly 
in  reference  to  the  agent  producing  such  condition. 

In  an  article  on  another  page  of  this  number  Dr.  Chapin 
has  called  especial  attention  to  the  fatal  effects  of  great 
heat  in  largely  increasing  the  mortality  from  infantile  diar- 
rhoea. As  shown  by  his  statistics,  susceptibility  to  a  high 
temperature  is  much  greater  in  early  life  than  in  adults. 

In  conclusion,  the  laity  should  have  impressed  upon  them 
the  great  importance  of  attending  at  once  to  any  loose- 
ness of  the  bowels  at  this  time.  A  diarrhoeal  condition 
of  the  intestine  is  a  favorite  developing  place  for  the 
comma-shaped  bacillus  that  Dr.  Koch  is  just  now  finding 
in  the  bowels  and  dejections  of  cholera  patients.  Every 
possible  means  should  be  taken  to  avoid  affording  a 
favorable  soil  for  this  bacillus,  in  case  it  finds  its  way  to 
our  shores.  It  is  certain  that  it  will  not  stay  long  if  it 
finds  a  limited  field  for  its  development.  The  possibility 
of  such  an  invasion  is  suggested  by  the  fact  that  a  ship 
has  lately  arrived  in  lower  quarantine  from  Marseilles, 
laden  with  a  cargo  of  wool. 


MEDICAL  CHARITY  IN  THE  SOUTH. 
We  publish  elsewhere  a  communication  from  Dr.  Shear- 
down,  of  Knoxville,  Tenn.,  in  which  he  goes  over  the  fa- 
miliar  ground  of  the  abuses  of  medical  charity.  It  is  inter- 
esting  as  showiqg  the  state  of  things  in  the  smaller  cities 
throughout  the  West  and  South ;  and  also  because  the 
author  makes  some  suggestions  as  to  remedies. 

Dr.  Sheardown  is  a  trifle  one-sided  in  his  description 
of  the  status  of  medical  charity.  It  is  to  be  remembered 
that  a  Urge  amount  of  medical  service  is  tendered  for 
the  sake  of  learning  or  teaching.  Medical  students  and 
young  practitioners  must  be  educated  and  must  learn 
their  art  practically.  They  are,  therefore,  glad  to  work  in 
hospitab  and  dispensaries  for  nothmg.  In  smaller  cities 
and  towns,  to  be  sure,  where  medical  colleges  do  not  ex- 
ist, this  factor  does  not  come  in  to  so  great  an  extent. 

We  think  that  it  would  be  better  also  that  the  profes- 
fiion  earn  less  money,  rather  than  gain  the  reputation  of 
being  hard-fisted,  and  always  demanding  the  quid  pro 
quo.  We  say  this  while  fully  aware  that  Dr.  Sheardown 
has  in  the  main  presented  the  question  correctly. 


SOME  PRACTICAL  FACTS   REGARDING  ASIATIC 
CHOLERA. 

As  to  Us  nature  and  mode  of  prevention, — Asiatic  cholera 
requires  for  its  development,  first,  a  specific  germ  of  poi- 
son ;  second,  a  proper  soil  for  the  poison  to  grow  in.  We 
may  not  be  able  to  keep  away  the  germ  by  quarantine, 
but  we  can  destroy  the  soil  by  disinfectants. 

"Excrement-sodden  earth,  excrement-reeking  air,  ex- 
crement-tainted water,"  these  are  for  Americans  the 
causes  of  cholera.l 

Cholera  attacks  the  most  insalubrious  places  in  a  city 
in  succession.  Hence  every  man  can  choose  whether 
I'e  will  live  in  a  nidus  for  the  disease  or  not.* 


The  poison  of  cholera  exists  in  water,  and  wet  soil 
chiefly,  also  in  food,  and  in  the  air  near  infected  spots 
only.  It  has  a  very  short  reach.  It  is  infectious  and 
portable,  but  not  contagious  in  the  ordinary  sense. 
Hospital  attendants,  nurses,  and  doctors,  if  careful,  are 
but  little  more  liable  to  the  disease  than  others  living  in 
the  same  locality. 

Koch's  cholera  bacillus,  if  really  a  pathogenic  agent 
(which  has  not  yet  been  proved),  is  only  one  of  the  factors 
necessary  to  develop  cholera. 

Maritime  quarantine  is  of  use  in  preventing  cholera. 
Inland  quarantine  and  sanitary  cordons  are  of  no  value. 
To  keep  clean  is  the  best  internal  quarantine. 

The  best  disinfectants  for  cholera  are  carbolic  acid, 
the  zinc  and  copper  salts,  and  corrosive  sublimate. 

There  are  no  specifics  against  the  attacks  of  cholera, 
except  perfect  domestic  and  personal  cleanliness,  tern- 
perate  living,  and  leaving  the  infected  spot. 

The  French  have  an  old  "preventive  of  cholera" 
which  runs  as  follows  : 

**  Tiens  tes  pattes  au  chaud, 
Tiens  vides  tea  boyaux, 
Ne  vois  pas  Marguerite, 
Du  chol6ra  tu  seras  quitte." 

The  prevalence  of  typhoid  fever  furnishes  a  fair  indi- 
cation of  the  extent  to  which  cholera  would  spread  if  it 
reached  a  city.  Such  is  the  conclusion  of  English  ob- 
servers. There  is  y^ry  little  typhoid  in  New  York  City 
now. 

Persons  living  in  low-lying  parts  of  a  city  or  town  are 
the  most  liable  to  cholera.  The  inhabitants  of  high  flats, 
properly  plumbed,  are  safe. 

Panics  over  cholera,  such  as  occurred  at  Toulon  and 
Marseilles,  show  ignorance  as  well  as  cowardice.  Mod- 
ern sanitation  can  hold  cholera  in  check. 

The  mortality  from  cholera  docs  not  average  over  fifty 
per  cent.  It  is  generally  less  toward  the  close  of  an 
epidemic.  The  mortality  is  less  in  those  treated  in  hos- 
pitals (in  England).  The  mortality  rate  varies  somewhat 
with  each  epidemic. 

The  duration  of  a  cholera  epidemic  in  a  given  com- 
munity is  several  months,  unless  it  is  "  stamped  "out  by 
sanitary  measures.  It  may  go  away  and  return  again 
the  next  year.  In  any  limited  locality  it  expends  its 
force  in  two  to  three  weeks. 

Of  individual  cases,  the  duration,  if  fatal,  is  about  two 
and  one-half  days,  if  non-fatal,  about  nine  days.  The 
period  of  incubation  of  cholera  is  from  two  days  to  a 
week. 

Diagnostic  points, — Painless,  profiise  diarrhoea  should 
excite  suspicion.  A  case  showing  such  symptoms  as 
non-feculent,  very  copious,  watery  stools,  of  a  rice-water 
character,  early  cramps,  quick  exhaustion,  low  tempera- 
ture, pinched  facies,  should  make  the  physician  very 
suspicious.  If  cholera  were  present  in  the  locality  his 
diagnosis  could  be  positive. 

Points  in  treatment, — Epidemic  cholera  is  generally 
preceded  by  a  painless  diarrhoea.  This,  if  attended  to 
at  once,  can  be  easily  cured  in  ninety-nine  per  cent  of 
the  cases.  HypodeHiiic  injections  of  morphine,  and  tiie 
internal  use  of  opium,  aromatics,  and  astringents,  are 
indicated  here.  In  the  collapse  stage  of  cholera  give 
ice-water  and  ice,  but  be  careful  in  the  use  of  stimulaats. 


July  26,  18H] 


THE  MEDICAL  RECORD. 


lOI 


Watch  the  pulse  to  see  if  they  affect  it     Horner's  anti- 
cbolera  mixture,  recommended  by  Hartshorn  and  Bar- 
tholow,  may  be  used  before  or  at  the  beginning  of  the 
stage  of  collapse. 
9.  Chloroform, 

TiDOt.  opii, 

Spts.  camph., 

Spts.  ammon.  aromat &&  f  3  jss. 

Creasote gtt.  iij. 

Olei  cinnamomi gtt.  vij. 

Spts.  vini  gall f  3  ij. 

M.    Sig. — Gtt.  X.  to  XX.  in  ice-water  every  five  minutes. 

A  hypodermic  injection  of  morphine  is  a  most  effective 
remedy  for  the  diarrhoea  and  cramps. 

Cholera  specifics  do  not  exist.  Oxygen,  saline  ven- 
oas  injections,  chloride  of  sodium  drinks,  warm  baths, 
calomel,  camphor,  venesection,  have  all  fiotiled. 


TOHT  CESSPOOLS,  THEIR  DANGERS   AND   REMEDIES. 

We  so  frequently  receive  letters  like  the  subjoined,  that 
we  have  concluded  to  answer  once  and  for  all,  at  least 
for  the  present,  in  our  pages  : 

Long  Island,  June  19,  1884. 

Dear  Sir  :  May  I  ask  a  favor  at  your  hands?  The 
water-closets  in  my  house  discharge  into  a  cesspool  of 
about  two  thousand  gallons  capacity.  This  is  of  brick, 
well  cemented,  and  supposed  to  be  tight ;  it  is  closed  by 
a  stone  slab  and  has  no  ventilation.  Its  contents  are 
poinped  out  and  put  upon  the  land  as  often  as  once  a 
month  in  the  summer,  and  in  winter,  when  full,  say 
ahout  once  in  three  months. 

In  my  water-closets  the  bottled  chlorides  are  freely 
used,  but  I  have  come  to  suspect  that  the  quantity  used 
is  not  sufficient  to  disinfect  the  cesspool.  The  arrange- 
ment of  the  plumbing,  soil-pipe,  etc.,  I  believe  to  be  good. 

Should  this  cesspool  be  treated  with  additional  disin- 
fectants ?  If  so,  how  often,  and  when  ?  When  full,  or 
when  just  emptied,  or  more  frequently  ?  Can  you  also 
^ve  me  an  idea  what  quantity  of,  sa^  a  saturated  solu- 
tion of  copperas,  or  anything  else  which  you  can  recom- 
mend as  better,  should  be  considered  enough  for  one 
application  ?  I  mention  the  strong  solution  of  copperas 
becaose  I  am  familiar  with  it,  and  always  keep  the  solid 
salt  by  the  barrel  on  hand  for  frequent  use  about  my 
premises,  stable,  etc.  .  It  is  cheap  and  in'  convenient 
form  for  solution.  Is  there  anything  better  ?  How  about 
carbolic  acid,  quicklime,  sulphur,  etc.  ? 

Yours  very  truly,  G.  T.  L. 

The  readers  of  The  Record  need  scarcely  be  told  that 
tig^t  and  unventilated  cesspools,  with  no  outlet  for  their 
gases  except  into  the  bath-tubs,  water-closets,  wash-basins, 
and  kitchen-sinks,  which  empty  into  them,  must  rank 
among  the  most  dangerous  of  all  "modern  conveniences'* 
tiiat  can  be  devised  by  the  perverse  ingenuity  of  man. 
They  are  far  more  dangerous  than  open  privies,  open 
cesspools,  and  more  or  less  ventilated  sewers.  The 
gases  which  are  formed,  and  the  germs  which  are  bred, 
in  darkness  and  heat,  with  little  or  no  oxidation  or  re- 
newal of  air,  are  annong  the  most  concentrated  and  viru- 
lent ;  far  more  injurious  and  destructive  than  ordinary 
seter  gases,  which  always  have  so  many  outlets  to  the 
open  ur.  A  closely  sealed  cesspool  is  a  many  multiply- 
iag  fool  air-chamber  or  foul  gas-retort.  Apart  from  the 
wdinary  unsavory  and  harmful  products  of  the  decom- 

positioD  of  vegetable   and  animal  matters  which  takes 


place  there,  all  the  discharges  from  pauents  sick  with 
measles,  scarlet  fever,  diphtheria,  summer  diarrhoea,  dys- 
entery, or  typhoid  or  intermittent  fever,  if  there  happens 
to  come  any,  also  become  more  virulent  Yet  just  such 
cesspools  are  among  the  most  common  additions  to  the 
largest  and  finest  country  houses,  and  are  regarded  as 
the  nicest  things  for  country  hotels  and  summer  board- 
ing-houses. They  are  very  numerous  in  the  most  fash- 
ionable watering  places.  It  is  not  uncommon,  in  some 
half-primitive  and  half-civilized  places,  to  find  out-door 
privies  for  the  male  boarders  and  up-stair  water-closets  for 
females,  the  pipes  from  which  empty  into  a  tight  cesspool. 
In  order  to  save  a  few  hundred  feet  of  drain-pipe  these 
cesspools  are  generally  placed  very  near  the  houses. 
Every  observant  person  has  seen  them  within  ten  feet, 
more  or  less,  of  parlor  or  bed-room  windows,  with  huge 
and  even  splendid  flower-pots  put  over  their  covers,  in 
order  to  hide  any  trace  of  their  existence.  Of  course, 
these  hotel  and  boarding-house  cesspools  cannot  be 
emptied  during  the  summer  season,  when  the  gases  and 
germs  in  them  become  abundant  and  virulent,  and  have 
no  escape  except  into  the  rooms  from  which  the  materials 
for  their  growth  and  composition  came.  When  con- 
sulted about  such  matters  it  is  well  to  advise  that  a  new 
cesspool  be  built  far  away  from  the  house.  It  should 
have  a  large  man-hole,  which  should  always  be  left  open 
for  free  ventilation  ;  then  such  great  quantities  of  fresh 
earth  should  be  thrown  into  it  from  time  to  time,  that  not 
only  all  fluids  and  moisture  should  be  neutralized  and 
absorbed,  but  all  its  foul  contents  should  be  covered  by 
at  least  six  inches  of  fresh  absorbent  earth.  In  short, 
the  cesspool  should  be  converted  into  a  great  and  whole- 
some earth-pit.  Thus  not  only  will  the  whole  contents 
be  kept  odorless  and  healthy,  but  all  the  waste  materials 
of  the  house  will  be  changed  into  an  excellent  and  in- 
offensive fertilizer,  which  can  be  used  in  gardens  as  well 
as  fields.  Every  open  out-door  privy  can  be  changed,  in 
the  same  simple  and  inexpensive  way,  into  an  outdoor 
earth-closet  by  throwing  in,  if  necessary,  one  or  several 
or  many  cart  loads  of  fresh  earth,  until  a  dry  surface  of 
earth  alone  is  visible,  and  all  offence  to  the  eye  and  nose 
is  obviated.  Then  fresh  earth  should  be  thrown  in  every 
day,  sufficient  to  hide  and  disinfect  the  daily  deposits. 
We  are  sure  that  this  earth  treatment  of  cesspools  and 
privies  would  pay  in  the  greatly  increased  quantity  of 
excellent  and  inodorous  fertilizers  which  would  be  gained ; 
for  earth  permeated  with  the  fluids  and  gases  of  decom- 
position is  almost  as  rich  as  garden  mould. 

It  requires  no  stretch  of  imagination  to  suppose  tiiat 
it  would  pay  to  have  earth  thrown  from  time  to  time  in 
every  horse-manure  pit,  and  over  the  contents  of  every 
stable-  and  barn-yard.  Horse,  cow,  and  cattle  manure 
would  thus  be  ripened  and  mellowed.  The  great  waste  of 
good  material  by  evaporation  from  the  heat  of  the  sun 
in  the  hot  months,  and  by  the  washing  and  soakage  of 
rain  in  wet  times,  would  be  largely  prevented.  An  en- 
thusiastic hygienist  says,  every  country  bam-  and  stable- 
yard  could  be  converted  into  a  wholesome  and  cleanly 
earth-yard,  where  every  one  could  almost  always  walk 
with  comfort  and  decency.  The  nasty  smells  of  stable- 
men, and  cow  and  cattle  herdsmen  would  also  be  largely 
done  away  with.  Many  of  the  diseases  which  arise  from 
the  discharges  of  sick  men,  horses,  and  cattle  would  be  pre- 


I02 


THE  MEDICAL  RECORD. 


[July  26, 1884, 


vented ;  the  occupations  of  stable  and  cattle  men,  and 
even  sweet  milkmaids,  would  become  much  more  cleanly 
and  wholesome.  The  amount  of  good  and  savory  fer- 
tilizers that  would  be  gained  would  be  almost  incalcul- 
able. The  air  of  every  country  house,  village,  and  small 
town  would  be  greatly  improved.  Places  naturally 
wholesome,  but  polluted  by  thoughtless  man's  filthy 
habits,  would  regain  their  primitive  healthfulness.  We 
have  heard  of  pleasant  and  productive  farm-yards  which 
were  hollowed  and  graded  toward  the  centre  to  prevent 
all  fluids  from  running  off  to  waste.  The  bottoms  were 
stamped  down  hard  to  make  an  impervious  base,  over 
this  about  six  inches  of  loose  earth  was  thrown,  and 
above  this  the  first  layer  of  the  droppings  of  horses  or 
cattle  or  both  were  thrown,  also  to  the  depth  of  six  or 
more  inches ;  then  a  fresh  layer  of  earth,  say  three  inches, 
and  so  on  successively,  layer  by  layer  of  earth  and  manure. 
Such  farmers  always  had  much  more  and  better  fer- 
tilizers than  their  neighbors.  Their  barn  and  stable 
yards  were  always  pleasant  and  wholesome,  their  stable 
jand  cattle  men  and  women  were  always  more  tidy,  sweet 
smelling,  and  cleanly.  The  milk  and  butter  was  better, 
and  spoiled  less  readily;  almost  all  infectious  human, 
horse,  and  cattle  diseases  were  prevented  or  quickly 
stamped  out,  and  that  without  other  scientific  or  chemi- 
cal aid. 

f —  I 

The  Greely  Arctic  Expedition. — The  reports  from 
this  expedition  show  that  Americans  can  live  for  two 
years  in  perfect  health  in  the  arctic  region,  and  that  the 
use  of  brackish  water  does  not  produce  scurvy. 

A  New  Insane  Asylum  for  Iowa. — A  new  asylum 
for  the  insane  is  to  be  built  at  Clarinda,  Iowa.  The  sum 
of  $50,000  has  been  appropriated  for  beginning  the 
work. 

Journalistic  Changes.  —  Dr.  T.  F.  Rumbold  has 
given  up  the  editorship  of  the  5/.  Louis  Medical  and 
Surgical  JournaL  Dr.  Le  G.  Atwood  becomes  editor 
in  his  place. 

Dr.  R.  B.  Stover  has  retired  from  the  editorship  of  the 
Atlantic  Journal  of  Medicine^  leaving  it  in  charge  of 
Dr.  Henry  G.  Houston. 

Dr.  Wesley  C.  Norwood,  a  prominent  physician  of 
South  Carolina,  and  a  medical  writer  of  note,  died  at 
Cokesburg,  S.  C,  June  17th,  at  the  age  of  seventy-eight. 
Out  of  a  handsome  competence  he  gave  magnificent  gifts 
of  money  to  Woflford  College,  South  Carolina,  and  Adger 
College,  South  Carolina. 

Dr.  Kirkbride's  Successor.  —  Dr.  John  Bassett 
Chapin,  Superintendent  of  the  Willard  Asylum  for  the 
Insane,  at  Willard,  N.  Y.,  has  been  unanimously  elected 
by  the  Board  of  Managers  of  the  Pennsylvania  Hospital 
for  the  Insane  to  succeed  Dr.  Thomas  S.  Kirk  bride,  de- 
ceased, as  Physician-in-Chief  and  Superintendent  of  that 
Institution.  The  Board  is  fortunate  in  having  secured  so 
able  and  accomplished  a  physician  as  Dr.  Chapin. 

The  Yellow-fever  Germ  not  Discovered. — Some 
months  since  considerable  interest  was  excited  by  the 
announcement  that  Dr.  Freire,  of  Rio  Janeiro,  had  de- 
tected the  presence  of  the  organism  causing  yellow-fever 


in  soil  taken  from  graves  of  persons  who  had  died  from 
the  fever,  and  that  he  had  succeeded  in  communicating 
the  disease  to  rabbits  and  guinea-pigs.    But  [Medical 
Press  and  Circular)  in  a  communication  since  forwarded 
to  the  English  Government  from  the  island  of  Barbados 
an  account  is  given  of  the  results  of  a  number  of  control 
experiments  made  with  soil  taken  from  the  graves  of  per- 
sons who  died  of  yellow-fever  in  the  epidemic  of  1881, 
and  from  open  fields  on  which  no  manure  had  been  used. 
Previously  sterilized  chicken-soup  impregnated  with  any 
of  these  moulds  and  kept  at  the  ordinary  temperature 
usually  became  turbid  in  a  few  hours,  and  by  the  second 
day  had  assumed  a  bright  yellow  color.     Summing  up 
their  results,  Messrs.  Moxly  and  Harrison  say  that  they 
can  discover  no  difference  between  a  micrococcus  from 
a  grave  and  one  from  a  garden. 

The  Legality  of  Cremation. — One  of  the  English 
courts  has  just  decided  that  it  is  illegal  to  cremate  a 
body  on  which  a  coroner  had  determined  to  hold  an  m- 
quest.  The  body  in  question  was  that  of  an  illegitimate 
infant,  and  the  decision  seems  an  eminently  natural  and 
proper  one. 

A  Grand  Fair  in  Aid  of  the  London  Hospitals  is, 
it  is  said,  to  be  undertaken  under  the  auspices  of  the 
Health  Exhibition.  The  hospitals  in  question  are,  many 
of  them,  in  great  need  of  pecuniary  help. 

A  Medical  Drama. — A  drama,  called  "  Sister  Grace," 
written  by  a  doctor,  and  played  for  the  benefit  of  the 
East  London  Hospital  for  Children,  has  just  been  pre- 
sented at  the  Avenue  Theatre,  London.  The  play  in« 
troduces  hospital  life  and  incidents.  The  binaural  steth- 
oscope made  its  first  appearance  on  the  stage. 

The  Death  of  Dr.  Moreau,  the  celebrated  alienist, 
at  Paris,  in  the  eighty-first  year  of  his  age,  is  announced. 
He  was  a  pupil  of  Esquirol,  and  had  been  attached  to 
Bicdtre  and  La  Salp^tri^re. 

The  Epidemic  of  Small-Pox,  which  has  for  some 
time  been  prevalent  at  Liverpool,  has  now  attained 
alarming  dimensions.  Traffic,  except  for  residents,  is  in 
certain  streets  suspended,  and  the  public  institutions  for 
the  reception  of  small-pox  patients  are  full  to  overflow- 
ing. It  is  stated  that  the  Local  Government  Board  have 
severely  censured  the  local  authorities,  and  have  called 
upon  them  to  immediately  provide  suitable  hospital  ac- 
commodation for  infectious  cases.  Small-pox  is  also 
still  very  prevalent  in  London,  there  having  been  over  a 
thousand  cases  in  the  hospitals. 

Excessive  Child  Mortality  in  New  York  City. — 
The  Lancet  estimates  that  the  mortality  rate  among  chil- 
dren under  five  years  of  age  in  New  York  City  is  90.3 
per  1,000  living  children,  while  in  London  it  is  onl) 
65.1  per  1,000,  a  diflference  of  thirty-nine  per  cent. 

The  Yellow  Fever  Germ. — The  Panama  physiciai 
who  claims  to  have  discovered  the  yellow  fever  germ,  t< 
have  cultivated  and  inoculated  it,  passed  through  thi 
city  last  week  on  his  way  to  Paris.  He  was  interviewee 
by  a  member  of  the  daily  press,  who  procured  a  picturi 
of  the  hypothetical  germs  and  produced  them  before  tht 
admiring  laity.  As  shown  in  wood-cuts,  they  certainl; 
look  like  very  ordinary  forms  of  fungus. 


July  26,  1884.] 


THE  MEDICAL  RECORD. 


103 


Dr.  Octave  Pavy,  Late  Surgeon  to  the  Greely 
I       ExpfiDinoNy  was  a  man  of  curious  character,  and  had 
led  a  varied  career.     He  was  born  in  Havre,  France, 
!      where  he  was  educated,  and  where  much  of  his  youth 
was  spent.    Early  in  life  he  accompanied  a  French  ex- 
I      pedition  to  Lady  Franklin  Bay,  and  spent  several  years 
in  the  polar  regions.     He  fought  in  the  Franco-Prussian 
war.  At  its  close  he  came  to  America,  where  he  resorted 
to  various  expedients  for  a  living.     He  finally  studied 
medicine,  and  began  practice  in  1877.     He  was  a  mem- 
ber of  the  Howgate  expedition,  and  when  this  failed  he 
remained  at  Disco  Island,  off  the  coast  of  Greenland, 
oDtil  he  joined  the  Greely  party. 

Dr.  William  Fruitnight,  one  of  the  medical  staff 
^Bellevue  Hospital,  died  suddenly,  July  21st,  at  the 
residence  of  his  brother.  Dr.  J.  Henry  Fruitnight,  from 
thrombosis  of  the  brain.  The  deceased  was  but  twenty- 
five  years  of  age.  He  was  graduated  from  the  Bellevue 
Hospital  Medical  College  in  1880,  and  since  that  time 
bsiA  been  attached  to  the  medical  staff  at  the  hospital. 

Professor  Virchow  has  begun  a  series  of  popular 
articles  on  cholera  in  Die  Nation^  a  weekly  political  jour- 
nal of  Berlin.  He  condemns  the  French  for  careless- 
ness,  and  takes  a  conservative  view  as  to  the  real  signifi- 
cance of  the  cholera  bacillus. 

Medical  Novelists. — Dr.  William  A.  Hammond  an- 
nounces that  he  has  four  novels  written,  and  intends 
hereafter  to  publish  two  a  year.  He  states  that  he  would 
lather  be  a  novelist  than  a  doctor,  and  thinks  that  it  is 
time  medical  oien,  in  a  literary  way,  give  some  results  of 
their  rich  and  peculiar  experience  with  human  nature. 

The  Illinois  State  Board  of  Health  held  its  quar- 
terly session  on  July  2d  The  Secretary  in  his  report  says : 
"There  have  been  fewer  complaints  made  direct  to  the 
Board,  of  unprofessional  conduct,  and  fewer  cases  of  this 
tind  otherwise  coming  under  observation,  during  this 
qaarter  than  ever  before  in  the  history  of  the  Board/' 
Taking  up  the  subject  of  public  health,  the  Secretary 
refers  to  the  prevalence  of  small-pox  in  England,  and  the 
probability  that  it  will  become  more  prevalent  in  this 
country.  He  advises  the  printing  and  distribution  of  the 
school  vaccination  order. 

Pasteur's  Experiments  on  the  Prevention  of 
Rabiks. — Further  experiments  have  been  made  by  M. 
Pasteur  on  the  prevention  of  hydrophobia  by  inoculation. 
Jie  has  experimented  upon  57  dogs,  19  of  which  were 
mad,  and  38  bitten  by  them  under  uniform  conditions. 
Out  of  these  2^^^  half  had  been  previously  inoculated. 
Those  not  inoculated  died  of  unmistakable  hydrophobia, 
^risereas  the  19  others  are  apparently  in  the  possession 
of  perfect  health. 

Death  of  Dr.  CiSSAR  Henry  Hawkins. — Dr.  Caesar 
Henry  Hawkins,  the  well-known  English  surgeon,  who 
lad  been  Sergeant  Surgeon  to  her  Majesty  Queen  Vic- 
toiiafor  a  number  of  years,  died  in  London,  July  21st, 
>t  an  advanced  age.  Dr.  Hawkins  was  bom  near  the 
<iosc  of  the  last  century.  After  having  served  for  a  few 
Tears  as  Lecturer  on  Anatomy  at  the  school  in  Great 
WiBdmiU  Street,  London,  he  was  appointed  surgeon  to 
^  George's  Hospital,  where  he  lectured  on  surgery,  and 
^ipidly  became  known  as  one  of  the  most  learned  prac. 


titioners  of  Great  Britain.  He  held  this  position  for 
thirty-two  years,  in  the  meantime  becoming  a  Trustee  of 
the  hospital,  until  1861,  when  he  resigned  and  was  ap- 
pointed consulting  surgeon,  a  post  which  he  filled  until 
his  death.  He  was  also  for  several  years  an  Examiner 
in  Surgery  at  the  University  of  London  and  a  member  of 
the  Court  of  Examiners  of  the  Royal  College  of  Surgeons, 
of  which  he  was  twice  elected  President.  He  served  at 
different  times  as  President  of  the  Royal  Medical  Society 
of  England,  the  Royal  Chirurgical,  and  the  Royal  Patho- 
logical Societies.  On  the  death  of  Sir  Benjamin  Collins 
Brodie,  Sergeant  Surgeon  to  Her  Majesty,  Dr.  Hawkins 
was  appointed  to  fill  the  vacancy  in  the  Queen's  house- 
hold. He  was  the  author  of  a  series  of  lectures  on  tu- 
mors, and  furnished  a  number  of  other  valuable  contri- 
butions to  medical  journals. 

Some  Advanced  Views  on  the  Subject  of  Medical 
Education. — The  Chicago  Medical  Society,  says  the 
Medical  Age,  has  lately  been  devoting  considerable  of  its 
attention  to  the  subject  of  the  regulation  of  medical 
practice  in  the  State  of  Illinois,  and  a  committee,  re- 
cently appointed  to  place  the  matter  in  shape  for  con- 
sideration, has  just  made  its  report.  The  committee 
hold  that  no  degree  of  the  doctor  of  medicine  should  be 
deemed  valid  if  conferred  by  any  medical  college  on  any 
one  who  shall  not  have  been  previously  examined,  as  to 
his  general  education,  by  a  committee  of  the  school  of 
practice  which  said  student  proposes  to  follow.  They 
believe  also  that  no  medical  college  should  hereafter  be 
incorporated  unless  it  have  an  endowment  fund  of  not 
less  than  $150,000  free  of  all  claims.  They  further  be- 
lieve that  no  person  should  be  permitted  to  enter  upon 
the  practice  of  medicine  unless  he  has  been  previously 
examined  by  a  board  of  seven  examiners  on  anatomy, 
physiology,  chemistry,  obstetrics,  gynecology,  surgery, 
practice  of  medicine,  hygiene,  State  medicine,  psychiatry, 
therapeutics,  materia  medica,  and  pharmacy.  This  board 
of  examiners  should  be  chosen  from  the  various  schools 
of  medicine,  in  proportion  to  the  number  of  practitioners 
of  each  schooL 

Cholera  in  the  Unfted  States. — There  have,  been 
five  importations  of  Asiatic  cholera  into  this  country, 
viz.,  in  1832,  1848-49,  1854,  1865-66,  1873. 

A  Veritable  Electrical  Girl. — A  propos  of  the 
Lulu  Hurst  nonsense,  which  has  lately  been  amusing 
New  Yorkers,  Dr.  Ch.  F6r6  publishes  editorially  in  the 
Progres  Midical  of  July  5th  the  account  of  a  genuine 
"electrical  girl."  He  describes  the  case  as  one  of  the 
"electric  neurosis."  The  patient,  a  woman  twenty-nine 
years  of  age,  had  been  under  observation  for  three  years. 
She  was  thin,  anaemic,  had  a  very  dry  skin,  and  suffered 
from  nervous  anorexia  and  ovarian  tenderness.  She  ap- 
peared to  be  charged  more  or  less  with  ^.positive  elec- 
tricity. Her  hair  when  stroked  would  crepitate,  and 
sparks  could  be  produced.  With  her  fingers  she  could 
repel  light  (electro-positive)  objects  and  attract  others 
(electro-negative).  She  was  in  fine,  in  the  condition  of 
one  who  has  been  slightly  charged  with  electricity.  This 
evolution  of  electricity  was  much  greater  when  her  emo- 
tions were  excited,  and  M.  F6r6  appears  to  think  that  the 
force  is  evolved  by  Mme,  X ,  and  not  that  it  accu- 
mulates through  friction  in  locomotion.   In  damp  weather, 


I04 


THE  MEDICAL  RECORD. 


Duly  26, 1884. 


the  phenomena  are  much  less  prominent,  and  when  this 
is  the  case,  the  patient  experiences  lassitude  and  malaise. 
Static  electricity  given  at  this  time  makes  her  feel  much 
better.  M.  F6re  considers  the  condition  the  result  of 
some  neuropathic  disturbance.  He  cites  several  some- 
what similar  cases  reported  by  Drs.  Girard,  Mussy,  Hos- 
fbrd,  Floquin,  and  others. 

Some  of  the  Work  which  Cholera  has  Done. — In 
187 1  there  were  300,000  deaths  from  cholera  in  Russia; 
in  1873  there  were  16,000  deaths  in  Poland;  iri  1872-73 
there  were  140,000 deaths  in  Hungary;  in  1872-73  there 
were  nearly  27,000  deaths  in  Prussia;  in  1865-67  there 
were  143,000  deaths  in  Italy.  In  Paris  the  mortality 
from  cholera  has  been  as  follows  :  in  1832,  18,654  deaths ; 
in  1849,  191^^4;  ^^  1^53-5493,096;  in  1865-66,  12,082; 
in  1873,  ^^5'  ^^  England,  in  1849,  the  deaths  from 
cholera  were  70,000.  In  181 7  the  army  of  the  Marquis 
of  Hastings  in  India  lost  9,000  men  in  twelve  days  from 
Asiatic  cholera. 

Progress  of  the  Cholera  in  Europe. — At  date  of 
writing  the  cholera  is  continuing  its  ravages  at  Toulon 
and  Marseilles  with  unabated  violence^  The  deaths 
at  the  former  place  average  daily  between  20  and  30 ; 
at  the  latter  between  50  and  60.  The  number  of  cases 
in  the  hospitals  at  Toulon  averages  about  200.  The 
record  for  July  21st  at  the  St.  Mandrier  Hospital  was : 
admissions,  14;  deaths,  2;  under  treatment,  122.  We 
may  infer  that  the  epidemic  is  not  a  specially  virulent  one. 
Cases  of  Asiatic  cholera  are  reported  at  Aries,  at  Nismes, 
and  at  Vienna.  Deaths  from  **  cholerine  "  are  reported 
at  Lyons.  Deaths  from  sporadic  cholera  have  been 
reported  at  Paris,  but  it  is  doubtful  as  yet  if  genuine 
cholera  has  reached  that  city.  The  French  authorities 
have  wisely  decided  not  to  undertake  any  inland  quaran- 
tine against  the  disease,  but  to  employ  suitable  inspec- 
tion. Quarantine  at  the  frontiers  of  Italy  and  Spain 
appears  to  have  been  carried  out  with  a  ridiculous,  if  not 
absolutely  harmful  stringency.  Koch  has  presented  to 
the  mayor  of  Toulon  a  memorandum  regarding  the  meth- 
ods for  preventing  cholera.  The  substance  of  it  is  as  fol- 
lows :  I,  cholera  is  propagated  l^  people,  and  is  gener- 
ally communicated  by  contact  with  human  beings  or 
clothes ;  2,  lead  a  very  temperate  life,  in  eating  as  well  as 
drinking ;  3,  see  that  your  food  comes  from  no  infected 
locality — cook  it  well ;  4,  see  that  the  water  for  drink- 
ing and  washing  is  pure,  boil  it  if  need  be ;  5,  avoid 
large  gatherings,  fairs,  etc. ;  6,  disinfect  choleraic  evac- 
uations with  carbolic  acid  ;  7,  the  apartments  of  cholera 
patients  should  be  left  uninhabited  for  six  days  ;  8,  per- 
sons who  have  been  in  contact  with  cholera  cases  should 
wash  their  hands^  in  soap  and  water  and  carbolic  acid ; 
9,  laundresses  should  not  take  the  linen  of  patients  till 
after  its  disinfection  ;  10,  the  .clothes  of  patients  should 
not  be  transported  until  after  disinfection;  11,  funerals 
should  be  as  plain  as  possible. 

The  French  Government  has  decorated  Koch  with  the 
cross  of  the  Legion  of  Honor. 

The  National  Dental  Association  held  its  fourth 
annual  session  in  Washington,  beginning  July  2  2d.  The 
President,  Dr.  R.  B.  Winder,  of  Baltimore,  presided. 
We  would  suggest  for  future  discussion  the  question, 
Why  dentists  always  convene  in  hot  weather?  | 


The  Importation  of  Rags  into  this  Country  from 
infected  ports  in  Europe  has  been  forbidden  by  the 
Government. 

Suicide  of  Dr.  William  M.  Dorran. — Early  on  the 
morning  of  July  2  2d  Dr.  William  M.  Dorran,  of  Mount 
Vernon,  N.  Y.,  shot  himself  in  the  head.  He  was  dead 
when  discovered.  Dr.  Dorran  was  bom  in  Ireland,  and 
was  fifty-two  years  old.  He  graduated  from  the  Univer- 
sity Medical  College  in  1863.  He  left  nothing  telling 
why  he  had  taken  his  life,  but  it  is  supposed  that  he  be- 
came despondent  over  continued  ill-health  from,  a  disease 
which  he  contracted  in  the  army,  while  stationed  at  Fort 
Scott,  Arkansas. 

New  Crematories. — Companies  have  been  organized 
in  Pittsburgh  Pa.,  and  Buffalo,  N.  Y.,  for  the  purpose  of 
building  crematories.  They  will  conduct  cremation  on 
a  business  basis,  and  doubtless  will  find  enough  '*  cranks" 
to  keep  their  furnaces  supplied. 

Peptonizing  Milk — A  Correction. — In  Dr.  Smithes 
letter  on  "  The  Feeding  of  Infants,"  etc..  Medical  Reg- 
ORD,  July  19th,  p.  80,  second  column,  it  should  read: 
"  Mix  a  powder  consisting  of  five  grains  of,  etc.,"  instead 
of  five  grammes. 

Final  Decision  Regardino  the  United  States 
Medical  College. — ^The  Court  of  Appeals  has  declared 
that,  according  to  the  intent  of  our  legislation,  the  words 
"literary  or  scientific  college  "in  the  amended  general 
statute  do  not  cover  medical  colleges,  respecting  the 
organization  and  management  of  which  there  is  a  special 
statute.  The  legal  defect  under  which  the  "United 
States  Medical  College  of  the  City  of  New  York"  labored 
fi-om  its  birth  not  having  been  cured  by  the  nicely  planned 
legislation  of  1882,  that  institution,  says  the  TlnteSj  has 
returned  to  the  nothingness  out  of  which  it  sprang. 

Is  IT  True  ? — It  is  generally  considered  better  not  to 
wash  in  public  the  linen  that  is  encumbered  with  adven- 
titious, sordid,  and  germ-breeding  products.  Alleged 
peculiarities  in  the  social  habits  of  the  American  Medicaji 
Association  doctors,  however,  have  lately  been  receiving 
not  only  a  national  but  a  European  laundressing.  We 
clip  the  following  from  the  Medical  Press  and  Circular ; 

Lack  of  Refinement  in  the  American  Medical  i 
Association. — A  resident  of  Washington  writes  to  thti 
New  York  Medical  Journal  as  follows  :  "  The  usual  disJ 
graceful  performances  took  place  at  the  receptions.  Mrsu 

L generously  opened  her  beautiful  house,  and  prQ 

vided  as  fine  a  table  as  Demenet  could  serve.  She  wa 
rewarded  by  having  men  stalk  in  (hats  on  their  heads 
from  the  front  room  to  the  dining-room,  where  thq 
fought  like  wolves  for  places  at  the  tables,  overturaiq 
piles  of  plates,  breaking  her  expensive  ornaments,  an 
soiling  her  rugs  with  pools  of  tobacco-juice." 

We  are  very  confident  that  the  description  thus  given  isi 
gross  exaggeration.  We  have  met  a  number  of  gentlemei 
who  attended  the  Washington  receptions  and  heard  a 
such  reports.  We  can  refer  also  to  the  authority  of  th 
Texas  Courier-Record  that  the  members  in  question  we^ 
a  "  grand,  grave  body  of  men,"  whose  lives  gave  proofs 
the  immortality  of  the  soul,  and  suggested  nothing  i 
prandial  rapacity  and  ill-timed  expectoration.  WasbinJ 
ton  correspondents  should  be  a  little  more  careful  i| 
criticising  their  medical  colleagues. 


July  26,  1884.] 


THE  MEDICAL  RECORD. 


105 


Reports  ot  ^ocUtUs. 


AMERICAN  OTOLOGICAL  SOCIETY, 

SivenUenih  Annual  Session^  held  at  Grand  Hotels  Cats- 
kill  Mountains^  JV.  Y.yjuly  15,  1884. 

The  American  Otological  Society  held  its  seventeenth 
annual  meeting  at  the  Grand  Hotel,  Catskill  Mountains, 
Tuesday,  July  15,  1884. 

Morning  Session. 

Id  the  absence  of  the  President,  Dr.  C.  H.  Burnett, 
Vice-President  Dr.  J.  S.  Prout  called  the  Society  to 
<ffder. 

The  first  business  was  the  appointment  of  a  Business 
Committee,  consisting  of  Drs.  F.  B.  Loring,  £.  W.  Bart- 
Jett,  and  A.  Alt. 

Dr.  Andrews,  of  Philadelphia,  was  invited  to  a  seat 
in  die  Society. 

Dr.  H.  Knapp,  of  New  York,  read  a  paper 

m  THE  indications  for  opening  the  mastoid  pro- 
cess,  BASKD  on   some  RECENT  OBSERVATIONS. 

In  it  he  described  three  cases,  which  were  cited  as 
dlostrations  of  some  of  the  conditions  in  which  this  oper- 
ation was  of  value.  The  first  case  was  one  of  acute 
tympano-mastoiditis,  in  which  paracentesis  of  the  tym- 
panic membrane  had  been  tried  without  afifording  any  re- 
Iie£  The  mastoid  process  was  trephined,  a  large  amount 
ofpus  removed,  and  this  was  followed  by  rapid  recovery. 
The  second  case  was  one  of  chronic  suppurative  tym- 
pmo-mastoiditis,  in  which  there  was  severe  half-sided 
headache.  In  this  case  relief  followed  the  operation. 
The  third  class  of  cases,  of  which  an  illustration  was 
dted,  was  sclerosing  mastoiditis.  In  this  case  the  tym- 
panic membrane  was  intact,  there  was  constant  severe 
headache.     Complete  relief  was  afforded  by  the  opera- 

tiOD. 

The  operation,  as  performed  by  Dr.  Knapp,  consists 
in  making  an  incision  one  centimetre  behind  the  inser- 
tion of  the  auricle,  the  point  of  election  for  perforating 
the  bone  being  the  pit  of  Dessarenne.  Chisels  alone  are 
tued  in  making  the  perforation.  The  direction  of  the 
openmg  should  be  parallel  to  the  course  of  the  external 
meam&  Especial  stress  was  laid  on  the  use  of  sponges 
in  die  cleansing  of  such  wounds.  The  advantage  being 
that  no  fibres  are  left  in  the  part. 

In  acute  suppurative  otitis  the  immediate  removal  of 
the  pus  is  sometimes  sufficient  to  cause  a  cure.  Syring- 
ing is  not  employed  unless  there  is  old  suppuration  or 
profuse  suppuration  sets  in  a  few  days  after  the  opera- 
tion. Where  it  is  wished  to  have  union  by  first  inten- 
tion, the  edges  of  the  wound  are  brought  together  with 
tiie  continuous  suture.  This  is  intended  after  operations 
ior  merely  congestive  sclerosing  processes,  or  when  in 
WMKsnppurating  otitis,  the  cranium  has  been  opened. 

For  washing  the  wound,  weak  solutions  of  chloride  of 
«dtam  or  boradc  acid  are  employed. 

Before  taking  up  the  discussion  of  this  paper,  the 
paper  of  Dr.  J.  A.  Lippincott,  of  Pittsburgh,  Pa.,  was 
Rad,  entitled, 

i  CASE  OF    mastoiditis  INTERNA  CHRONICA  WITH  SCLS* 
ROSIS — ^TREPHINING — RECOVERY. 

A  young  lady  nineteen  years  old  was  first  seen  March 
X5i  1883,  at  which  time  siie  complained  of  moderately 
terere  pain  from  which  she  had  suffered  several  months. 
Her  previous  health  had  been  good.  Tlie  watch  could 
be  heard  when  placed  against  the  ear.  A  quantity  of 
vax  was  removed  fi^m  the  canal  and  the  tympanic  niem- 
Inae  found  to  be  red  and  irritated.  The  removal  of  the 
VOL  did  not  cause  much  improvement  in  hearing,  which 
ns  one-diirtieth  in  the  right  ear.  The  left  ear  was  nor- 
BaL   Sli^t  catarrh  of  the  naso-pharynx  was  found.     A 


solution  of  boric  acid  and  borax  was  ordered  to  be  in- 
stilled ;  this  caused  some  relief.  But  five  weeks  later, 
the  suffering  greatly  increased  and  the  pain  y(dA  referred 
to  the  region  of  the  middle  ear  and  to  the  mastoid  pro* 
cess.  It  was  also  felt  in  the  whole  side  of  the  head. ' 
There  was  a  great  deal  of  swelling  over  the  process  and 
below  it.  Examination  of  the  ear  showed  that  the  mem- 
brane was  not  congested,  but  the  typical  light-cone  was 
absent  and  the  anterior  two-thirds  of  the  membrane 
showed  a  silvery  lustre.  The  Eustachian  tube  was  per- 
vious. There  was  slight  elevation  of  temperature. 
Leeching  and  poultices  were  applied  extemsdly,  and 
calomel  and  a  febrifuge  administered  internally.  This 
caused  rapid  improvement 

The  note  of  the  case  made  April  28th  was  as  follows  : 
Continuous  dull  pain  in  the  ear  and  mastoid  process. 
The  swelling  has  entirely  disappeared.  Hearing  two- 
thirtieths.  Tunbg-fork  on  vertex  heard  best  on  the  af- 
fected side. 

During  the  following  months  the  pain  continued  to  in- 
crease in  severity  and  was  especially  felt  in  the  mastoid 
region.  Hearing  steadily  diminished.  There  was  no 
swelling,  and  cerebral  symptoms  were  absent.  The 
treatment  consisted  in  the  use  of  blisters,  and  other  ap- 
plications, incisions  and  anti-neuralgic  and  alterative 
remedies  internally. 

On  March  20,  1884,  an  incision  was  made  behind  the 
auricle  under  ether,  and  an  opening,  seventeen  millime- 
tres in  depth,  was  made  with  Buck's  drill.  The  osseous 
tissue  was  hard  and  ivory-like.  A  carbolized  tent  was 
inserted  and  a  poultice  applied. 

After  the  operation,  the  pain  was  greatly  relieved  and 
entirely  disappeared  in  a  few  weeks.  Shortly  after  the 
operation,  a  return  of  the  pain  was  produced  by  expos- 
ure, but  this  was  at  once  relieved  by  the  application  of 
an  ointment  of  the  yellow  oxide  of  mercury  and  bella- 
donna. 

On  July  8,  1884,  the  patient  was  entirely  free  firom 
pain  and  the  hearing  was  six-thirtieths. 

Dr.  a.  H.  Buck,  of  New  York,  thought  that  it  was 
not  desirable  to  attempt  to  obtain  union  by  first  inten- 
tion. He  had  always  believed  that  the  good  results  of 
the  operation  were  largely  dependent  on  the  irritation 
and  drain  which  it  produced. 

Dr.  Knapp  said  that  the  only  ease  in  which  he  had 
tried  to  secure  healing  by  first  intention  was  in  one  in 
which  the  lateral  sinus  had  been  opened. 

Dr«  Charles  J.  Kipp,  of  Newark,  N.  J.,  had  come 
across  a  number  of  cases  in  which,  while  there  was  no 
external  evidence  of  disease,  carious  bone  was  found 
after  separating  the  periosteum,  and  cited  an  illustrative 
case. 

Dr.  Samuel  Theobald,  of  Baltimore,  Md,  considered 
the  administration  of  constitutional  remedies  a  very  im- 
portant part  of  the  treatment,  often  obviating  the  neces- 
sity for  operation.  He  had  obtained  excellent  results 
firom  the  use  particularly  of  iodide  of  potassium  and  the 
biniodide  of  mercury.  With  these  he  had  used  inunc- 
tions of  mercurial  ointment  and  the  oleate  of  mercury. 

Dr.  Sexton,  of  New  York,  exhibited  a  number  of  phQto- 
graphs  and  briefly  described  the  cases  which  they  illus- 
trated. He  differed  from  Dr.  Knapp  in  the  conclusions 
which  he  had  drawn.  He  did  not  think  that  pain  alone 
was  a  sufficient  ground  on  which  to  base  a  diagnosis  of 
involvement  of  the  mastoid  process. 

Dr.  J.  A.  Andrews  stated  that  one  of  the  indications 
by  which  he  was  guided  in  opening  the  mastoid  cells  was 
the  occurrence  of  swelling  of  the  optic  disk  or  optic  neu- 
ritis. When  this  appeared  in  a  case  in  which  there  was 
restlessness,  and  pain,  he  performed  the  operation. 

Dr.  a.  Mathewson,  of  Brooklyn,  stated  that  in  many 
of  the  fatal  cases  of  aural  disease,  post-mortem  examina- 
tions failed  to  reveal  any  evidences  of  mastoid  disease. 

Dr.  a.  H.  Buck  described  the  method  which  he  pur- 
sued in  these  cases.  They  can  be  divided  into  two 
classes:  in  one  the  mastoid  disease  develops  in  a  well 


106 


THE  MEDICAL  RECORD. 


[July  26, 1884, 


Dr.  J.  J.  B.  Vermyne,  of  New  Bedford,  Mass.,  read 
the  next  paper,  which  was  entitled 

DISEASE  OF  THE  ETHMOID,  THE  CONSEQUENCE  of 
CHRONIC  CATARRH  OF  THE  NASO-PHARYNX— EXOPH- 
THALMOS, 

in  which  was  described  the  case  of  a  young  lady  of  six- 
teen, who  consulted  the  author  on  account  of  a  slight 
protrusion  of  the  right  eye.   The  protrusion  was  forward 
and  downward  and  had  existed  for  some  time.    The  eyt- 
lids  were  not  cedematous.     There  was  no  dilatation  of 
the  veins,  the  conjunctivae  were  normal  and  pam  was 
absent.     Ophthalmoscopic  examination  showed  that  the 
optic  disk  was  slightly  elevated  and  that  the  vessels  of 
the  retina  were  dSstended.     There  was  slight  hyperme- 
tropia  on  the  right  side,  but  vision  was  normal  on  both 
sides.     Headache  had  been  noticed  for  a  few  days  be- 
fore she  came  under  observation.    The  general  health 
was  good  with  the  exception  of  a  chronic  naso-pharyngeal 
catarrh,  which  had  existed  for  eleven  years  and  which 
had  followed  a  severe  attack  of  scarlet  fever.    This  was 
particularly  marked  on  the  right  side.     The  movements 
of  the  right  eyeball  were  not  interferred  with.    There 
was  slight  diplopia  on  awakening  in  the  morning,  but 
this  continued  only  for  a  short  time.     A  neoplasm  in  or 
around  the  nerve  was  suspected  and  the  treatment  di- 
rected accordingly.     In  a  short  time  the  patient  entirely 
recovered  with  Sie  exception  of  the  protrusion  of  the  eye. 
A  further  consideration  of  the  case  led  the  author  to 
think  that  possibly  the  symptoms  might  be  explained  on 
another  supposition  than  that  of  a  neoplasm.     A  careful 
examination  was  again  made,  and  a  hard  inunovable 
nodular  tumor,  extending  from  the  upper  internal  corner 
of  the  eye  to  the  internal  canthus,  and  which  evidently 
was  connected  with  or  originated  from  the  os  planum, 
was 'found.     The  symptoms  were  then  referred  to  the 
naso-pharyngeal  catarrh   and  suitable    treatment  insti- 
tuted.   The  case  was  considered  to  be  one  of  retention 
tumor,  similar  to  one  which  was  reported  by  Dr.  Knapp, 
in  1876,  to  the  International  Ophthalmologicai  Congress. 
This  opinion  was  largely  based  upon  the  fact  that  there 
had  been  frequently  observed  a  peculiar  appearance  of 
the  eye,  which  was  compared  to  a  lobster  eye.    The 
speaker  referred  to  the  fact  that  Dr.  Knapp's  case  had 
been  successfully  operated  on  by  the  chisel :  a  plan  of 
treatment  which  Dr.  Knapp  had  advised  in  all  cases  of 
this  kind  whether  of  exostosis  or  of  retention  tumors. 
Another  case  of  Dr.  Knapp's,  reported   in   the  April 
number  of  the  Archives  of  Otohgyy  was  referred  to.   The 
above  operation  was  performed,  but  the  patient  died  from 
traumatic  meningitis.     Disease  of  the  osseous  walls  oJ 
the  frontal  sinus  was  found  after  death.    In  reviewing  the 
conclusions  drawn  by  Dr.  Knapp  from  the  last  case,  th( 
speaker  though  it  proper  to  ask  what  constitutes  a  com- 
paratively healthy  pneumatic,  and  whether  some  participa 
tion  of  the  bone  in  the  neighborhood  of  the  tumor  can  no 
with  reason  be  suspected  ?  And  also,  considering  the  le^ 
danger  which  might  attend  simple  mechanical  distentioi 
of  the  bone,  whether  an  explorative  puncture  with  : 
trocar  would  not  become  imperative,  instead  of  beiqi 
unnecessary,  as  stated  by  Dr.  Knapp,  and  whether  ii 
tmmors  of  this  kind,  when  not  endangering  the  eye  am 
not  of  inconvenient  size,  it  would  not  be  better  to  Ic 
them  alone  as  has  been  advised  by  other  authorities  ? . 
'     Dr.  Vermyne  also  read  a  paper  on  \ 

MYXOFIBROMA  AT  THE  BASIS  CRANII,  CAUSING  BLINDNESS 
AND  SEVEN  YEARS  LATER,  COMPLETE  DEAFNESS  BY  Dl 
STRUCTION  OF  THE  LABYRINTH. 

The  patient  was  first  seen  in  the  early  part  of  i87< 
dimness  of  vision  and  fatigue  of  the  eye  being  coi 
plained  of.  Vision  =  ^  There  was  slight  congestion  \ 
the  optic  disk  and  of  the  retinal  vessels.  Three  monll 
later,  severe  headache  and  optic  neuritis  appear^ 
Under  the  use  of  the  artificial  leech  and  the  adouniM 
tion  of  large  doses  of  bromide  and  iodide  of  potassin 


person ;  in  the  other  it  develops  in  one  who  has  had 
for  some  time  a  purulent  discharge  from  the  ear.  If  the 
disease  supervenes  in  an  old  case  of  ear  trouble,  tender- 
ness, redness,  and  swelling  of  the  glands  will  probably  be 
absent,  although  serious  disease  of  the  mastoid  process  is 
present  The  next  question  is  whether  or  not  there  is 
adequate  provision  for  the  discharge  of  matter.  If  there 
is  not  the  operation  should  be  performed.  In  the  acute 
cases  he  considered  it  good  surgery  to  operate  on  the 
mastoid  process. 

The  paper  was  discussed  further  by  Drs.  Jones,  Seely, 
Pooley,  Mathewson,  and  Fryer. 

Dr.  a.  H.  Buck,  of  New  York,  in  a  paper 

ON  THE  USE  OF  LARGE  DOSES  OF  IODIDE  OF  POTASSIUM 
AND  IODIDE  OF  SODIUM  IN  THE  TREATMENT  OF  CASES 
OF  RAPID   LOSS   OF   HEARING 

supposed  to  be  due  to  syphilitic  disease,  reported  several 
cases  which  he  had  collected  in  studying  the  literature  of 
the  subject.  In  two  of  these,  benefit  had  followed  anti- 
syphilitic  treatment  He  added  to  this  a  detailed  account 
of  a  number  of  cases  treated  by  himself  with  large  doses 
of  the  iodides,  in  none  of  which  had  a  cure  been  effected 
and  in  only  one  or  two  had  temporary  benefit  been  ob- 
tained. He  had  given  the  iodide  in  doses  as  large  as 
five  hundred  and  twenty-five  grains  per  diem,  without 
any  beneficial  effects.  He  thought  that  this  was  prob- 
ably due  to  the  fact  that  the  disease  had  destroyed  the 
organs  essential  to  the  perception  of  sound,  and  although 
the  source  of  pressure  which  had  caused  this  injury  might 
be  removed,  the  destruction  had  been  such  that  the  organ 
did  not  regain  its  functions. 

Dr.  Seely  stated  that  his  experience  had  led  him  to 
the  conclusion  that  if  benefit  did  not  follow  moderate 
doses  of  anti-syphilitic  remedies  it  was  not  to^be  ex- 
pected. 

Dr.  Buck  had  reached  the  same  conclusion. 

Drs.  Mathewson,  Jones,  Knapp,  and  Andrews  also 
took  part  in  the  discussion,  and  reported  cases  similar 
to  those  described  by  Dr.  Buck  in  which  the  results 
of  treatment  had  been  negative. 

Adjourned. 


Evening  Session. 

The  first  paper  read  at  the  evening  session  was  by  Dr. 
Seely,  of  Cincinnati,  O.,  on 

THE   TREATMENT    OF    SUPPURATHTE    OTITIS    MEDIA  WITH 
JEQUIRITY. 

After  referring  to  the  failure  of  the  various  plans  of  treat- 
ment in  this  affection,  he  stated  that  in  oider.  to  obtain 
the  best  results,  it  was  necessary  to  fulfil  the  following 
conditions :  first,  cleanliness ;  second,  rendering  and  keep- 
ing; the  Eustachian  tube  patulous ;  and  third  putting  the 
naso-pharynx  into  a  healthy  state.  This  last  point  is 
frequently  entirely  ignored.  The  mucous  membrane  of 
the  cavity  of  the  tympanum  frequently  passes  into  such 
a  condition  that  it  can  only  be  relieved  by  changing  it 
into  cicatrical  tissue ;  a  condition  similar  to  that  found  in 
tracheomatous  inflanunation  of  the  conjunctiva. 

This  latter  affection  has  recently  been  treated  by  indu- 
cing a  violent  inflammation  by  means  of  the  infusion  of 
jequirity.  For  the  past  year  or  two  Dr.  Seely  has  been 
treating  certain  cases  of  long-standing  suppurative  otitis 
media,  by  inducing  inflammation  with  the  solution  of 
jequirity  which  has  been  used  in  the  treatment  of  similar 
diseases  of  the  eye,  and  he  considers  this  plan  of  treat- 
ment of  value  under  certain  conditions,  which  he  formu- 
lated as  follows :  i,  where  there  is  extensive  destruction  of 
the  membrana  tympani ;  2,  where  there  is  a  great  amount 
of  thickening  of  the  mucous  membrane,  thus  rendering 
other  plans  of  treatment  futile  or  tedious ;  and  3,  where 
there  is  a  patulous  Eustachian  tube,  a  condition  for  regu- 
lating the  inflammation. 


July  26,  1884.] 


THE  MEDICAL  RECORD. 


107 


the  patient  improved  The  patient  passed  from  under 
observation  on  account  of  the  statement  to  the  patient's 
parents  that  there  was  probably  a  cerebral  tumor,  and 
that  the  improvement  was  likely  to  be  only  temporary. 

Five  years  later  the  patient  was  again  seen,  and  sec- 
ondary atrophy  of  both  optic  disks  was  found.  In  1873 
she  became  deaf ;  but  six  weeks'  later  she  could  hear 
almost  as  well  as  before.  After  this  the  hearing  gradu- 
ally disappeared.  The  patient  died  in  May,  1874,  ^ig^t 
and  a-haJf  years  after  the  first  observation. 

At  the  autopsy,  a  tumor  measuring  six  centimetres  in 
lei^9  four  centimetres  in  width,  and  two  centimetres  in 
thickness  was  found  occupying  the  left  inferior  occipital 
fossa.  The  left  half  of  the  cerebellum  had  been  com- 
pif^ed  to  one-third  of  its  normal  size.  The  consbtence 
of  the  cerebellum  was  increased,  and  both  it  and  the 
cerebrum  were  anaemic.  A  considerable  amount  of  fluid 
vas  found  in  the  ventricles.  The  tumor  in  its  growth 
bad  impinged  upon  the  petrous  portion  of  the  temporal 
bone  of  the  left  side,  and  had  caused  the  entire  destruc- 
tion of  that  portion  of  it  between  the  posterior  wall  and 
the  tympanic  cavity,  which  had  been  opened. 

The  speaker  considered  that  the  first  symptoms  of  the 
ttsDor  were  those  referred  to  the  eye  ;  that  in  all  prob- 
ability the  tumor  originated  from  the  dura  mater,  and  that 
the  e£fect  upon  sight  and  hearing  was  to  be  attributed 
entirely  to  interference  with  the  circulation  from  mechani- 
cal pressure. 

Dk.  Charlks  Kipp  reported  two  cases  of  a  similar 
nature,  m  one  of  which  the  frontal  sinus,  the  ethmoidal 
ceQs^  and  the  sphenoidal  cells,  were  filled  with  innumer- 
able polypL 

A  CASE   OF   EPITHELIOAiA  OF  THE  AURICLE 

was  reported  by  Dr.  Charles  J.  Kipp,  of  Newark.  The 
grovth  developed  in  a  young  man  aged  nineteen,  and 
had  been  growing  for  one  year.  It  involved  the  concha 
and  closely  resembled  a  mass  of  granulation  tissue,  but 
it  was  harder  than  this,  and  this  condition  led  to  the 
diagnosis  of  granuloma.  It  was  removed,  the  wound 
healed,  and  the  case  passed  from  under  observation,  so 
that  its  subsequent  history  could  not  be  obtained  The 
miaoscope  showed  the  growth  to  be  made  up  to  a  great 
extent  of  epithelial  cylinders,  imbedded  in  a  very  vascu- 
lar, fine  fibrillar  tissue. 

Dr.  Kipp  also  exhibited  a  cavernous  fibro-lipoma  which 
be  bad  removed  by  excision  from  the  auricle  of  a  man 
thirty-one  years  of  age. 

Dr.  L.  Howe  rea!d  a  paper  entitled 

IL£MAT0MA   AURIS — ITS  TREATMENT  WITH   ERGOT. 

The  condition  had  occurred  in  a  sane  woman  aged 
tvcDty-eight,  without  apparent  cause.  Hypodermic  in- 
jections of  ergot  were  tried  with  the  effect  of  greatly  di- 
BunishiDg  the  size  of  the  auricle. 

Dr.  Samuel  Sexton  read  a  paper  on 

THE  influence     OF   DENTAL   IRRFTATION   ON   THE     EAR. 

A  nomber  of  plaster  casts  were  exhibited,  showing  the 
condition  of  the  teeth  in  cases  in  which  the  ear  symp- 
toms were  found  to  be  due  to  the  caries  or  other  trouble 
vi&  the  teeth,  and  in  which  relief  was  only  obtained 
«i^  these  difficulties  were  corrected. 

The  following  papers  were  read  by  title  :  Dr.  Todd's, 
of  St.  Louis,  Mo.,  entitled,  "  Necrosis  of  the  Right  Laby- 
mth;  Total  Facial  Paralysis  on  the  same  Side ;  Partial 
lecovcry;"  Dr.  Burnett's,  of  Philadelphia,  Pa.,  on 
'^Iteflex  Aural  Phenomena  from  Naso-Pharyngeal  Ca- 
toik ;  Objective  Noises  in  and  from  the  Ear ; "  and  Dr. 
H.  N.  Spencer's,  entitled,  "  A  Simple  Device  for  the 
li'atiiient  of  Nasal  and  Post-nasal  Inflammations,  and 
a  the  Importance  which  Attaches  to  such  Conditions 
tf  iBflammation  as  they  are  Related  to  the  Ear.** 

Pkopkssor  F.  E.  Clarke  read  a  paper  in  which  he 
s^  for  a  reliable  test  for  hearing,  by  which  the  differ- 

t&cc  between  hearing  and  feeling  might  be  determined  ; 


for  a  method  by  which  the  hearing  might  be  developed 
or  improved,  and  whether  injury  might  be  done  in  these 
cases  by  loud  noises,  etc. 

The  paper  was  referred  to  a  committee  of  three,  of 
which  the  President  of  the  Society  was  to  be  chairman. 

The  Society  then  went  into  executive  session. 

The  new  members  elected  were  :  Dr.  E.  D.  Spear,  Jr.,. 
Boston  ;  Dr.  John  Vanduyn,  Syracuse,  and  Dr.  S.  O. 
Richey,  Washington. 

officers  for  the  ensuing  year. 

President— Dr.  C.  H.  Burnett,  Philadelphia  ;:  ^^'^- 
President— Dr.  J.  S.  Prout,  Brooklyn ;  Secretary  and 
Treasurer— Dr.  J.  J.  B.  Vermyne,  New  Bedford,  Mass. ; 
Committee  on  Publication — Dr.  J.  J.  B.  Vermyne,  Dr.  C 
J.  Blake,  Dr.  O.  J.  Green  ;  Committee  on  Membership — 
Dr.  John  Green,  Dr.  H.  G.  Muller,  Dr.  H.  O.  Moyes. 

The  next  meeting  to  be  held  at  the  same  place  as  the 
American  Ophthalmological,  and  on  the  day  preceding 
its  meeting. 

The  Society  then  adjourned. 


THE  PARIS  ACADEMY  OF  MEDICINE^ 

I  Stated  Meetings  June  24,  1884. 

M.  Alphonse  Gu^rin,  President,  in  the  Chair. 

(Spccui  Report  for  Thb  Mbucal  Rbcord.) 

The  Academy  having  been  called  to  order,  M.  Fauvel^ 
at  the  request  of  several  of  the  members,  made  a  short 
report  upon 

the  cholera  in  toulon. 

He  had  already  had  occasion,  before  the  Consulting 
Committee  on  Hygiene  of  France,  to  express  the  opinion 
which  he  held  that  the  present  epidemic  was  not  Asiatic 
cholera.  All  the  (acts  in  connection  with  the  case  go  to 
prove  that  the  disease  is  of  local  origin,  and  is  due  to  the 
herding  together  of  a  considerable  number  of  troops 
placed  under  defective  hygienic  conditions.  These  same 
conditions  have  before  now,  notably  in  England,  caused 
outbreaks  of  epidemics,  attended  with  great  mortality. 
Such  epidemics  are  ephemeral,  continuing  and  subsiding 
along  with  the  conditions  which  have  ^ven  occasion  to> 
them.  The  mode  of  origin  of  the  epidemic  in  Toulou,. 
and  its  subsequent  course,  have  nothing  in  common  with, 
our  ideas  of  Asiatic  cholera.  Whenever  this  dreaded 
disease  visits  a  large  community,  it  strikes  with  great  fury 
and  advances  with  extreme  rapidity,  so  that  it  reaches  its. 
maximum  of  intensity  within  a  few  days,  having  then  at- 
tacked all  those  who  are  susceptible  to  its  influence. 

M.  J.  Gu^RiN  asked  that  M.  Fauvel  might  be  a 
little  more  explicit  in  his  report,  so  that  the  Academy 
might  not  be  dependent  upon  the  daily  papers  for  infor- 
mation concerning  the  Toulon  epidemic. 

M.  Fauvel  regretted  that  he  would  not  be  able  to 
give  any  more  detailed  information  until  the  next  meet-^ 
mg.  He  could  state,  however,  positively,  that  the  epi- 
demic was  declining. 

M.  Boulev  announced  that  MM.  Roux  and  Straus 
had  left  for  Toulon,  and  would  bring  back  some  valuable 
documents  bearing  upon  the  origin  and  nature  of  the 
disease  there  prevailmg.  These  documents  would  be- 
laid  before  the  Academy  when  the  question  of  thecholera 
epidemic  came  up  for  discussion. 

M.  BucQUOY  then  related  a  case  of 

FARCY, 

occurring  in  a  coachman,  nineteen  years  of  age.  The 
patient,  who  had  been  ill  for  a  fortnight,  presented  all 
the  symptoms  of  typhoid  fever,  except  that  there  were 
no  rose-colored  spots  nor  any  gurgling  on  pressure  in 
the  right  iliac  fossa.  A  little  later,  M.  Bucquoy  noticed 
a  small  round  ulcer  on  the  external  suriace  of  the  ri^t 
leg,  and  an  abscess  a  little  higher  up  on  the  limb.   With^ 


io8 


THE  MEDICAL  RECORD. 


[July  26,  1884. 


in  a  short  time  the  patient  had  a  severe  chill,  and  this 
was  followed  by  swelling  and  redness  about  the  right 
ankle.  Suppuration  soon  appeared  within  the  joint. 
Several  of  the  other  articulations  became  similarly 
aififected,  the  patient  rapidly  lost  strength,  and  finally 
died.  Just  before  death  the  body  was  nearly  covered  with 
an  eruption  of  bullae.  The  author  inoculated  an  ass 
with  fluid  taken  from  the  body  of  this  patient,  and  the 
animal  sickened  with  farcy,  thus  showing  conclusively  the 
nature  of  the  disease  from  which  the  young  man  had 
suffered.  It  was  ascertained  afterward  that  the  patient 
had  slept  in  a  stable  in  which  was  a  horse  affected  with 
glanders. 

A  communication  to  the  Academy  from  Madame  Pa- 
quereau,  regarding  the  interests  of 

MIDWIVES   IN   ALGERIA, 

was  then  reported  upon  by  M.  de  Villiers.  He  declared 
himself  in  favor  of  recognizing  the  midwives  practising 
in  that  colony. 

The  Academy  then  adjourned. 


THE  BIOLOGICAL  SOCIETY  OF  PARIS. 

Stated  Meetings  June  21,  1884. 

M.  Paul  Bert,  President,  in  the  Chair. 

(Special  Report  for  THb  Mbdical  Rjbcokd.) 

The  Society  having  been  called  to  order  by  the  Presi- 
dent, M.  BocHEFONTAiNE  read  a  communication  on  the 

ACTION   OF   salicylic  ACID    UPON   RESPIRATION. 

He  had  observed  the  effects  of  the  drug  upon  healthy 
individuals  and  those  suffering  from  typhoid  fever.  The 
respiratory  movements  became  more  regular  under  its 
influence,  probably  by  reason  of  its  action  upon  the  me- 
dulla oblongata. 

M.  DlsjERiNE  had  recently  been  studying  the 

PERIPHERAL  NERVE-LESIONS   IN   LOCOMOTOR   ATAXIA, 

and  presented  a  report  of  his  investigations  to  the  So- 
ciety. The  man,  a  patient  in  M.  Vulpian's  service,  had 
a  sclerosis  of  the  posterior  and  lateral  columns.  There 
was  complete  anaesthesia  of  both  lower  extremities,  with 
the  exception  of  a  small  area  on  the  inner  surface  of  the 
right  knee,  where  sensation  was  preserved.  M.  D^jerine 
found  marked  changes  in  all  the  peripheral  nerves  except 
those  suppl3dng  the  area  of  preserved  sensation.  The 
lesions  were  less  marked  in  the  cord  than  in  the  nerves. 
The  author  insisted  upon  the  importance  of  this  localized 
beuritis  in  the  symptomatology  of  ataxia. 
M.  DuMONTPALLiER  related  a  case  of 

INDUCED   BILATERAL   HALLUCINATIONS. 

The  subject  was  an  hysterical  female  who  had  been 
h3rpnotized.  While  in  the  somnambulistic  state,  a  card 
was  placed  perpendicularly  between  the  eyes  so  as  to 
divide  the  field  of  vision  into  two  parts.  A  pleasant 
image  being  presented  to  one  eye  and  a  disagreeable  one 
to  the  other,  the  impressions  thus  conveyed  to  the  hemi- 
spheres were  reflected  back  to  the  corresponding  halves 
of  the  patient's  countenance.  These  impressions  per- 
sisted even  after  the  patient  was  awakened,  the  two  sides 
of  the  face  expressing  the  opposite  sentiments  of  joy  and 
grief.  M.  Dumontpallier  believed  that  he  was  the  first 
to  produce  these  suggestions  to  the  brain  by  influencing 
the  retina  alone. 

M.  Glsy  had  endeavored  to  repeat  the  experiments  of 
M.  Aphanasieff  in  the 

TRANSFUSION   OF   PEPTONIZED    BLOOD. 

He  had  at  first  made  use  of  peptones  of  German  manu- 
facture, but  had  found  them  too  impure  for  this  purpose. 


He  had,  however,  succeeded  in  arresting  coagulation  by 
means  of  a  liquid  obtained  by  the  washing  and  macera- 
tion of  a  pig's  stomach. 

M.  Beauregard  described  the 

HEART   OF  THE   SPERMACETI   WHALE, 

which  he  had  recently  had  an  opportunity  to  examine. 
It  measured  nearly  three  feet  in  length  by  a  foot  and  a 
half  in  width,  and  was  of  an  oval  shape.  The  right  auri- 
culo-ventricular  valve  had  three  segments,  the  lefk  had 
four.  The  sigmoid  valves  were  without  any  nodules. 
The  bone  of  the  heart  was  absent  The  heart  of  the 
spermaceti  whale  would  thus  appear  to  be  intermediate 
between  that  of  the  ordinary  whale  (balaena)  and  the 
dolphin.  AiiLOther  point  worthy  of  mention  was  that 
the  walls  of  the  left  heart  were  no  thicker  than  those  of 
the  right. 

M.  P.  Bert  remarked,  regarding  the  equality  in  thick- 
ness  in  the  walls  of  the  two  sides  of  the  heart,  that  this 
was  as  it  should  be  physiologicalljr,  since  in  the  whale 
the  blood  was  to  be  propelled  horizontally  and  not  up- 
ward. One  could  easily  understand  that  it  would  re- 
quire a  stronger  heart  to  pump  the  blood  upward  into 
the  head  of  a  giraffe  than  forward  into  a  whale's  head. 

M.  Okorovitz  then  read  a  note  upon 

ideoplasty, 

or  the  physiological  realization  of  ideas. 

This  was  followed  by  some  further  remarks  by  M. 
Bert  upon 

ANiESTHESIA  FROM  DILUTED   CHLOROFORM  VAPOR. 

He  agreed  with  M.  Aubean,  who  had  read  a  commu- 
nication upon  the  same  subject  at  the  preceding  meet- 
ing of  the  Society,  that  the  best  mixture  was  one  of  eight 
parts  of  chloroform  to  a  hundred  parts  of  air.  This 
mixture  caused  death  in  a  dog  in  three  hours  ;  but  if  the 
strength  was  reduced  to  six  per  cent,  the  fatal  termina- 
tion was  delayed  for  nearly  seven  hours.  Although  man 
bears  chloroform  better  than  the  dog,  M.  Bert  thought  it 
advisible,  nevertheless,  after  anaesthesia  had  been  pro- 
duced by  the  eight  per  cent,  mixture,  to  reduce  the 
strength  somewhat  The  author  stated  further  that  when 
an  animal  had  once  fallen  into  the  most  profound  an»»- 
thesia,  it  would  absorb  no  more  chloroform  until  the 
aneesthesia  had  begun  to  diminish. 

M.  Brown-S^quard  related  a  case  of 

CHLOROFORM  NARCOSIS  MAINTAINED  FOR  EIGHT  DAYS. 

The  patient  was  an  epileptic  who  had  sustained  a 
fi-aciure  of  the  arm,  and  it  was  consequently  of  para- 
mount  importance  to  prevent  the  convulsions  for  a  time. 
Two  of  his  assistants,  medical  men,  were  his  authority 
for  the  assertion  that  the  sleep  had  not  been  interrupted 
during  the  whole  of  this  time.  Simpson  has  recorded  two 
cases  in  which  chloroform  narcosis  was  prolonged  for  three 
days. 

After  the  election  of  a  new  member  the  Society  ad- 
journed. 

Mr.  Gamgee's  Sponge.— Mr.  Sampson  Gamgee  has  re- 
cently shown  his  new  absorbent  sponge  before  the  Soci6te 
de  Chirurgie.  The  description  of  it  is  as  follows  :  "A 
small  capsule,  containing  eucalyptus  or  other  antiseptic, 
was  enclosed  in  absorbent  cotton ;  outside  of  this  was  a 
layer  of  cocoanut  fibre,  and  outside  of  this  more  ab- 
sorbent cotton-wool ;  the  whole  being  enclosed  in  gauze. 
When  about  to  be  used  the  capsule  could  be  broken  by 
a  blow  of  the  fist,  and  the  absorbent  cotton  become  per- 
meated with  the  antiseptic.  He  said  these  sponges  could 
be  made  at  a  very  ^nfling  cost,  and  hoped  they  would 
come  into  use  as  a  cheap  substitute  for  ordinary  sponges ; 
they  possessed  this  great  advantage,  that  when  required 
for  use  they  were  certain — however  long  they  might  have 
been  kept— to  be  antiseptic  :  and,  being  so  cheap,  they 
might  always  be  destroyed  after  being  used." 


July  J6,  1884.] 


THE  MEDICAL  RECORD. 


109 


(SmxtsponAmce, 


THE  QUESTION  OF  THE  FLORIDA  CLIMATE. 

To  THE  EnTOR  or  Thk  Mbdicax.  Rkcosd. 

Sir  :  The  nnmber  of  phthisical  cases  visiting  Florida  dur- 
ing the  winter  of  1 883-^4,  physicians  and  landlords  assured 
the  writer  during  a  stay  of  some  months  there,  was  greater 
than  ever  before.  Gainesville  may  have  been  an  ex- 
ception, but  certainly  not  if  scarcity  of  suitable  food 
and  accommodations  are  a  criterion.  Approaching 
Gainesville  from  the  direction  of  Palatka  the  country  is 
almost  an  unbroken  level,  as  it  is  in  leaving  Gainesville 
and  proceeding  toward  the  Gulf  coast ;  this  topographical 
characteristic  has  probably  been  observed  by  thousands 
fhohave  visited  Gainesville,  as  well  as  myself.  There  is 
therefore  no  natural  fall  nor  inclination  of  streams  toward 
any  great  river  nor  the  Gulf  of  Mexico,  no  basis  for 
oatoral  drainage.  The  construction  of  artificial  drains 
would,  owing  to  the  level  surface,  involve  great  expense. 
The  Alachua  Sbk,  a  few  miles  distant,  would  from  a 
sanitary  standpoint  be  considered  rather  as  a  source 
from  which  the  germs  of  malarial  disease  might  be  dis- 
seminated during  the  spring  and  autumn  months,  than 
otherwise.  Practically,  the  throat  leading  to  it  is  choked 
up  with  debris  and  the  surrounding  country  overflowed 
by  a  vast  and  virtually  stagnant  pool  of  fresh  water,  into 
which  the  element  of  vegetable  decomposition  must  of 
necessity  enter,  aided  by  absence  of  outlet  and  the  flat 
configuration  of  the  land.  The  calcareous  deposits  and 
in  places  marshy  soil  account  for  the  inferior  quality  of 
the  drinking-water  in  those  parts. 

With  reference  to  the  large  number  of  deaths,  a  clergy- 
man well  known  and  high  in  the  church,  one  who  has 
spent  many  winters  in  Florida,  and  one  certainly  not 
Qiely  to  make  such  an  assertion  unless  founded  upon  the 
finty  rock  of  fact,  affirms  that  during  his  visit  in  Gaines- 
riDe  deaths  from  phthisis  occurred  nearly  every  day  or 
two,  and  that  cadavers  were  frequently  removed  by  ni|rht 
km  the  hotels  by  the  back  door,  in  order  that  depressmg 
iafloences  might  not  be  exerted  upon  patients,  non- 
phthisical  or  otherwise.  Darkness  cannot  conceal  the 
eold. white  face,  and  the  little  world  in  the  "  Land  of 
flowers  **  knows  that  another  is  gone  to  his  or  her  long 
kme. 

One  word  about  Cedar  Key,  or  Cedar  Keys  as  it  is 
written  in  not  a  few  books  and  maps  and  so  called  by  in- 
habitants.    During  a  sojourn  there  the  prettiness  of  the 
fole  place,  with  its  row  of  bearing  orange-trees  on  either 
ide  of  the  street,  impressed  itself  upon  my  mind.   There 
I  a  certain  balminess  in  the  air  not  noticeable  on  the 
itiantic  side.     The  approaches  are  perfectly  flat,  and 
ftere  is  no  obstruction  to  the  mild  zephyrs  coming  over 
ie  placid  waters  of  the  Gulf  or  across  the  numerous 
Ettle  keys  studded  with  palms  and  cedars.    It  is  a  typical 
ipot  to  which  Tampa,  although  much  farther  south,  bears 
resemblance,  and  if  phthisical  cases  ought  to  be 
RDt  to  Florida  at  all,  which  is  extremely  doubtful,  they 
iQold  certainly  derive  more  benefit  anywhere  on  the 
lestero  coast  than  along  the  borders  of  the  Atlantic 
kean.     There  is  naturally  considerable  jealousy  be- 
rival  towns  eager  to  secure  the  greatest  number  of 
■tors,  and  doctors  differ  as  widely  in  their  views  about 
biida  as  a    health  resort  as    about   anything    else, 
pnions  founded  logically  upon  reason  and  individual 
tion  are  not  likely  to  be  changed,  and  further  argu- 
t  upon  the  subject  would  not  only  be  futile  but  would 
be  trespassing  idly  upon  the  valuable  pages  of  The 
)ICAL  Rkcord.     Yours  very  truly, 

G.  Halsted  Bovland,  M.D. 

jKra,s8a4. 

Thk  White  of  an  Egg  must  no  longer  be  looked 
IM  as  a  simple  albuminous  body.    Leboute,  Goumoens, 
,  and  recently  Dr.  E.  T.  Reichert  have  found  that 
exists  in  it  a  globulin  and  a  peptone. 


THE  ABUSE  OF  MEDICAL  CHARITY  IN  THE 
SOUTH.* 

To  THK  Editok  op  Thb  Msdical  Rboobo. 

Sir  :  I  desire  to  direct  your  attention  to  the  evils  of  charity 
practice  as  conducted  in  our  city,  and  in  fact  not  only 
in  Knoxville,  but  also  throughout  the  country  at  large, 
wishing  to  place  myself  on  record  as  opposed  to  the 
present  custom.  I  will  also  endeavor,  with  a  few  brief 
remarks,  to  suggest  a  more  satisfactory  mode  of  practice^ 
both  to  the  practitioner  and  to  the  worthy  poor. 

I  take  it,  we  all,  every  one  of  us,  are  practising  our 
profession  for  our  bread  and  butter,  however  much  we 
may  speak  of  the  honor  and  glory  attendant  upon  the 
practice  of  our  truly  progressive  science.  When  we  are 
called  to  a  patient  we  expect  and  certainly  ought  to  re-, 
ceive  compensation  for  our  services,  and  yet  how  many 
are  there  among  us  who  have  not  scores  upon  scores  of 
pauper  patients  upon  their  account  books,  and  who  is 
there  among  us  who  does  not  go,  always  go,  time  after 
time,  to  the  same  pauper  patients,  knowing  beforehand 
that  we  will  never  receive  any  pay  for  our  services  ?  I 
am  speaking  now  of  pauper  patients  as  a  whole,  includ- 
ing all  classes — all  who  are  recipients  of  gratuitous 
practice.  It  is  a  thankless  practice,  whether  we  treat  a 
miserable  dead-beat  or  a  deserving  pauper.  To  the  busy 
practitioner  the  attendance  on  the  pauper  class  directly 
takes  money  from  his  pocket,  consuming  valuable  time, 
time  which  could  otherwise  be  given  to  the  better  classes 
of  his  clientele.  As  it  now  is,  the  busy  active  doctor 
will  often  attend  before,  and  give  more  attention  to  a 
poor  patient  than  to  a  well-to-do  patient,  for  the  simple 
reason  that  he  is  afraid  it  will  hurt  his  reputation  if  he 
fails  to  find  time  to  wait  upon  the  poor  who  call  upon 
him.  He  is  afraid  some  one  will  say,  ''Oh  !  Dr.  So-and- 
so  will  not  call  and  see  me  because  I  am  poor."  He 
does  not  attend  the  poor  from  a  feeling  of  duty,  for 
honor,  glory,  or  fame,  but  simply  out  of  policy.  Policy 
is  a  fine  scheme.  Leave  policy  out  of  consideration, 
and  I  think  a  number  of  reputed  benevolent,  warm- 
hearted physicians  would  be  shorn  and  bereft  of  their  lau- 
rels. Mind,  I  do  not  say  all.  I  only  say  a  number.  I 
know  there  are  hundreds  who  are  really  deserving  of 
their  reputation  for  warm-heartedness,  benevolence,  and 
philanthropic  measures  ;  but  ^fter  all  is  said  and  done, 
we  are  but  human,  we  doctors,  and  we  practise  for  dol- 
lars and  cents. 

Another  feature  is  the  character  of  treatment  we  render 
to  the  poor.  And  right  here  I  will  say  I  expect  1  will 
receive  censure  for  saying  that  I  think  die  majority  of  us 
neglect  the  poor.  I  do  not  think  we  are  as  careful  and 
painstaking  with  them  as  we  ought  to  be.  While  here 
and  there  we  may  find  a  conscientious  practitioner,  one 
who  will  give  as  much  attention  to  a  pauper  as  to  first-* 
class  pay  patients,  I  am  free  to  say  I  do  not  believe  that 
the  majority  of  us  give  them  the  care  and  attention  wc 
ought  and  that  they  deserve.  For  I  hold  that  no  man, 
in  any  business  whatever,  not  even  the  profession  of  med-. 
icine,  will  give  without  a  quid  pro  quo^  the  same  care, 
energy,  thought,  and  attention  that  he  would  bestow  for 
a  consideration. 

Perhaps  before  continuing  further  it  would  be  weU 
to  make  a  division  or  separation  into  classes  of  those 
who  are  called  charity  patients.  I  divide  them  inta 
simply  two  classes :  first,  dead-beats ;  second,  the  wor- 
thy poor.  There  is  no  need  of  further  subdivision. 
These  two  classes  include  the  whole  mass  of  charity  pa* 
tients.  Of  the  truly  worthy  and  needy  poor,  I  have  this 
to  say  :  it  is  the  duty  of  every  man,  in  whatever  walk  of 
life  he  may  move,  to  help,  relieve,  and  succor  a  poor^ 
distressed,  and  afflicted  brother,  he  being  worthy.  It 
is  the  bounden  duty  and  becomes  the  solemn  obliga- 
tion of  every  village  and  county  to  take  care  of  their 
worthy  poor ;  but  because  it  is  right  and  just  that  the 

'  This  letter  is  the  substance  of  an  address  delivered  before  the  Knox  County 
Section  of  the  East  Tennessee  Medical  Society,  May  09,  1884. 


no 


THE  MEDICAL  RECORD. 


[July  26,  1834. 


worthy  poor  should  be  taken  care  of^  it  is  not  right,  nor 
is  it  just,  that  the  care,  labor,  attention,  and  in  many 
•cases  expenses  also,  necessary  for  their  assistance  and 
relief  should  be  saddled  upon  a  few  only  of  the  commu- 
nity, simply  because  they  always  have  shouldered  the 
burden  and  carried  it,  not  only  without  compensation  but 
without  murmur  or  grumbling.  To  be  sure,  ours  is  a  lib- 
eral profession  (in  more  senses  than  one)  and  in  all  ages 
and  all  time  we  have  ever  been  ready  and  willing  to  re- 
spond to  the  call  of  charity,  not  only  with  money  itself 
but  with  the  knowledge,  skill,  and  understanding  of  treat- 
ment our  professional  attainments  should  be  composed 
of.  This  is  a  very  mistaken  idea.  This  is  all  wrong. 
Because  we  have  heretofore,  do  now,  and  probably  will 
hereafter  do  these  things  is  no  reason  why  we  should  be 
imposed  upon.  A  free  horse  should  not  be  ridden  to  his 
death.  Yet  it  is  our  own  fault,  all  our  own  fault ;  the 
remedy  lies  in  our  own  hands.  We  can  stop  this  wrong 
system  of  practice  if  we  only  will  do  it. 

I  have  talked  with  numbers  of  our  profession,  both  here 
and  elsewhere,  and  I  have  yet  to  find  the  first  man  who 
does  not  condemn  and  deplore  the  present  system  of 
practice,  and  yet  all,  not  one  exception,  but  express 
themselves  as  ready  to  attend  the  needy  poor.  To  dis- 
tinguish always  between  the  worthy  and  unworthy  poor 
is  not  easy.  The  dead-beats  we  all  know  (after  we  get 
through  with  them) ;  those  who  run  up  a  bill  and  employ 
you  as  long  as  they  dare,  and  then  apply  to  some  one 
else,  because,  perhaps,  they  don't  wish  to  lay  themselves 
liable  to  be  refused  your  services  ;  perhaps  because  they 
are  ashamed  to  call  you  in  after  they  have  made  large 
bills.  They  are  the  ones  who  dodge  you  on  the  street 
corner,  iv^ho  would  rather  go  squares  around  than  pass 
your  office  or  house.  In  this  way  they  go  the  rounds, 
and  every  new  doctor  is  sure  to  be  overrun  with  these 
patients,  who  owe  every  doctor  in  the  neighborhood,  and 
in  this  way  get  their  entire  professional  services  free,  as 
it  takes  them  their  lifetime  to  make  the  rounds  of  every 
physician  in  a  city  of  this  size.  Some  of  them,  it  is  true, 
die  before  they  get  clear  around.  Sad,  is  it  not !  Then, 
too,  there  is  a  singular  peculiarity  about  these  miserable 
dead-beats  ;  it  is  this,  they  more  frequently  call  you  out 
at  night  for  trifling  ailments.  If  a  farmer  living  in  the 
country,  he  cannot  spare  a  horse  or  man  from  the  field 
to  send  after  you  in  the  day-time,  but  must  needs  wait 
until  night,  after  the  day's  work  is  done,  and  thus  entail 
double  duty  on  man  and  beast,  for  he  never  goes  himself, 
but  sends  a  neighbor. 

There  is  another  important  feature  with  this  class  of 
practice  :  nine-tenths  of  all  the  suits  for  malpractice  one 
has  or  may  hear  of,  if  one  takes  the  trouble  to  look  them 
up,  will  be  found  to  have  been  instituted  by  some  misera- 
ble scoundrel  of  a  dead-beat.  You  find  them  all  alike. 
They  are  the  men  who  find  it  cheaper  to  move  than  to 
pay  rent,  and  as  they  move  back  and  forth  through  the 
•city  leave  their  bills  at  drug  stores,  at  the  grocer's  and  at 
the  butcher's  unpaid.  You  recognize  the  man.  You  all 
know  him.     These  are  plain,  unvarnished  truths. 

Perhaps  I  have  drawn  out  and  spread  over  too  much 
paper  my  conception  of  the  evils  of  the  present  sys- 
tem of  charity  practice.  In  treating  of  the  remedy, 
which  I  claim  lies  in  our  own  hands,  I  will  try  and  be 
more  brief,  and  at  the  same  time  give  a  clear  outline 
of  what  I  conceive  to  be  the  best  way  out  of  the 
dilemma.  Let  me  preface  by  saying  that,  did  this  prob- 
lem lie  before  any  other  class  of  men  than  physicians  it 
would  be  quickly  and  readily  solved.  But  physicians 
are  proverbially  unbusinesslike.  As  one  of  the  first 
steps  toward  reform  in  this  direction  let  us  make  out, 
and  keep  up  and  compare  full  and  complete  black-lists, 
not  merely  talk  of  it  and  once  in  several  years  exchange 
a  hasty  memoranda  of  delinquents,  but  regularly  every 
quarter,  say,  revise  the  old  black-lists  carefully  and  make 
such  additions  and  alterations  as  is  necessary,  bring  your 
new  list  to  your  medical  society,  each  man  hand  his 
list  to  the  secretary,  and  have  the  secretary  make  out  a 


complete  list  and  furnish  one  to  each  member  of  the 
society,  have  them  in  printed  form  if  desired.  By  doing 
this  in  earnest,  not  making  a  farce  of  it,  we  will  accom- 
plish a  great  deal.  We  will  create  more  of  an  mterest  in 
our  society.  We  will  bind  ourselves  more  closely  to- 
gether, and  will  naturally  work  more  harmoniously  to- 
gether, and  be  in*  better  shape  to  secure  the  accomplish- 
ment of  our  desires  whatever  they  may  be. 

We  should  not  only  have  one  city  physician,  but  we  all 
should  be  city  physicians^  and  receive  pay  in  proportion 
to  the  amount  of  work  we  do.  Another  thing,  in  regard 
to  the  city  hospital  Under  the  present  regime  the 
hospital  practice  is  in  the  hands  of  a  select  few.  If  any 
outsider  has  an  interesting  case,  which  of  a  necessity  is 
obliged  to  avail  himself  of  hospital  privileges  and  accom- 
modations, he  is  obliged  to  turn  over  his  patient  to  the 
select  few.  In  Stillwater,  Minn.,  a  city  of  fifteen  thou- 
sand population,  where  I  practised  some  little  time  be- 
fore removing  to  Knoxville,  any  physician  in  the  city  was 
privileged  to  take  a  patient  to  the  city  hospital  and 
wait  upon  him  himself.  The  system  worked  well,  and  is 
in  vogue  to-day  in  Stillwater,  giving  excellent  satisfac- 
tion. 

In  several  parts  of  the  old  country,  in  Germany,  which 
I  recall  in  particular,  where  an  individual  is  sick,  or 
members  of  his  family  are  sick  and  need  professional 
care  and  is  unable  to  pay  for  same,  he  makes  applica- 
tion to  one  of  the  town  officials  for  aid.  The  official 
gives  him  an  order  to  a  physician  (the  applicant  select- 
ing his  ph3rsician)  to  wait  upon  him,  and  also  gives  him 
an  order  to  the  apothecary  for  necessary  medicines, 
which  order  must  be  countersigned  by  the  physician. 
Then  the  physician  and  apothecary  present  their  orders 
to  the  treasurer  or  proper  official  and  are  paid  their 
bills.  A  certain  schedule  of  prices  being  authorized  by 
law  at  a  certain  per  cent,  discount  from  the  regular  fee- 
bilL 

In  some  parts  of  Michigan,  also  in  Lancaster,  O.,  a 
similar  law  prevails.  Other  places  that  have  this  system 
I  cannot  now  recall.  In  our  own  city,  perhaps,  the  best 
way  is,  when  a  pauper  requires  medical  attention  let  him 
apply  to  the  alderman  of  his  ward — aldermen  are  usually 
pretty  well  acquainted  with  the  people  of  their  wards  (at 
least  immediately  preceding  a  municipal  election) — and 
let  the  alderman  be  empowered  to  give  an  order  to  any 
physician  the  applicant  prefers ;  at  the  same  time  giving 
an  order  to  the  apothecary  for  the  necessary  medicines, 
this  order  to  be  countersigned  by  the  physician  to  be  of 
any  value. 

If  this  work  is  considered  by  the  aldermen  as  derog- 
atory to  their  official  dignity  and  position  as  city  fathers, 
let  the  proper  power  be  conveyed  to  the  assessor  and  his 
deputies.  If  their  duty  is  already  too  arduous,  let  there 
be  constituted  an  additional  Board  of  Poor  Commis- 
sioners, one  or  more  to  each  ward,  with  a  nominal 
salary.  But  to  whosoever  this  power  be  relegated,  make 
it  obligatory  upon  them  to  personally  familiarize  them- 
selves, either  before  or  immediately  after  giving  the 
order,  with  the  worldly  condition  and  financial  standing 
of  the  applicant  in  order  to  guard  against  imposture,  and 
also  make  it  obligatory  upon  them  to  keep  a  full  record 
of  all  orders  drawn,  giving  name  of  applicant  and  mem- 
bers of  family,  his  and  their  occupation,  and  the  amount 
of  money  earned  by  the  family ;  by  this  means  ascertain- 
ing whether  they  are  worthy  recipients  of  charity  or  not 
Let  them  also  keep  a  record  of  the  date  of  application, 
and  names  of  physician  and  apothecary  whom  orders  are 
drawn  upon.  Make  it  also  a  duty  of  the  physician  to 
render  a  full  report  of  each  case  to  the  Board  of  Poor 
Commissioners,  all  proper  blanks  being  furnished  by  the 
city.  Then  let  us  physicians  adopt  a  charity  fee-bill ; 
either  a  new  one  designed  for  this  class  of  practice  or 
make  a  certain  per  cent,  discount  from  our  regular  fee- 
bill. 

These  are  my  ideas  on  the  evils  of  charity  practice  and 
of  the  proper  course  of  treatment  indicated.    If  this  treat- 


July  26,  i884>] 


THE  MEDICAL  RECORD. 


Ill 


nent  is  adopted  and  adhered  to,  I  think  the  prognosis 
cxtremelf  fevorable.  Bat  the  profession  must  be  united 
in  its  emleavors.  In  union  there  is  strength.  United  we 
irill  make  a  success  of  it ;  divided  we  will  ignominiousiy 

T.  W.  Sheardown,  M.D. 

jiBHtvnix,  TtaiH.,  May  29,  1884. 


MORPHOLOGICAL    STATUS    OF    THE    CERE- 
BELLUM. 

To  THB  Edttok  or  Thb  Mbdicai.  Rbcord. 

Sir:  I  have  read  with  considerable  interest  the  elaborate 
lectures'  delivered  under  the  provisions  of  the  Cartwright 
bequest  by  Professor  Wilder.  Having  given  attention  to 
tbe  matters  with  which  that  distinguished  anatomist  deals, 
pennit  me  to  offer  some  suggestions  regarding  a  single 
proposition  made  by  him  which  cannot,  I  think,  be  sus- 
tained The  lecturer  follows  the  lead  of  a  number  of 
comparative  anatomists  in  regarding  the  cerebellum  as  a 
distinct  segment  of  the  primitive  group,  under  the  name 
of  meUncephalon.  He  goes  further  than  they  in  creating, 
as  it  were,  a  new  ventricular  subdivision,  in  order  to 
render  this  classification  consistent  This  is  the  anterior 
portion  of  what  all  authorities  have  agreed  in  regarding 
as  the  fourth  ventricle,  according  to  Wilder  the  epkalia. 

Practically  we  all  recognize  that  the  cerebellum  is  an 
mportant  segment  of  the  adult  brain  ;  indeed,  the  clas- 
sification of  the  parts  of  the  adult  brain,  useful  for  med- 
ical students  and  for  the  localizationalist,  can  scarcely  be 
made  to  correspond  to  morphological  or  embryological 
reqoirements.*  I  need  but  refer  to  the  case  of  the  thala- 
mus, which  is  an  outgrowth  of  the  embryonic  thalamen- 
tfihalon^  and  really  one  of  the  finest  representatives  of 
an  embryonic  segment  which  could  be  cited.  In  man 
and  higher  aninoals,  however,  so  intimate  has  become  its 
secondary  fusion  with  the  medullary  centre  of  the  hemi- 
spheres, that  it  assumes  the  position  of  an  intracerebral 
ganglion,  comparable  to  the  lenticular  nucleus  and  the 
caudate  mass  of  the  corpus  striatum.  So  absolute  is  the 
dominion  of  the  cerebrsd  hemisphere  over  the  thalamus, 
dat  die  ventricular  cavity  of  the  former,  in  man  and  apes 
It  least,  encroaches  on  the  dorsum  of  the  thalamus  a 
^rt  distance  beyond  the  caudo-thalamic  groove,  as  if 
to  falsify  the  embryonic  relations  of  the  derivative  cere- 
bral vesicle  to  its  parent  thalamic  vesicle.  I  cite  this 
case  to  show  that  the  embryonic  importance  of  a  segment 
is  not  a  proper  gauge  of  its  importance  to  the  physiolo- 
gist and  physician  and  that  therefore  conversely  the  im- 
portance of  a  segment — ^like  the  cerebellum — to  the  physi- 
dogist  and  physician  is  not  an  indication  that  it  occupies 
a  correspondingly  important  place  in  the  embryologist's 
olcolations.  To  a  certain  extent  the  aims  of  morpho- 
logical and  physiological  anatomy  are  distinct.  To  the 
comparative  anatomist  the  pituitar)*  body  and  pineal 
gland  are  of  much  more  fundamental  importance  than 
»hc  pyramid  tract,  while  the  physiologist  discards  the 
fcnncr  and  attaches  the  greatest  value  to  an  accurate 
bowledge  of  the  latter,  just  as  the  surgeon  is  more  in- 
tttttted  in  understanding  the  mechanism  of  the  atlanto- 
occipital  articulation  than  in  being  told  by  the  morpholo- 
pst  that  the  ligamentum  suspensorium  denii  epistrophei 
ODteins  a  notochordal  relic.  I  say  this  with  a  full  ap- 
pRciation  of  the  high  biological  importance  of  even  un- 
pnctical  facts»  which,  if  I  could  attest  in  no  other  way, 
I  needed  but  to  refer  to  a  few  original  discoveries  which 
I  have  been  fortunate  enough  to  stumble  across  while 
undertaking  researches  in  this  field. 

The  reasons  why  I  cannot  agree  in  regardbg  the  cere- 
beDom  as  a  primary  segment,  nor  the  epicalia  as  a  pri- 
oaij  ventricular  subdivision,  are  the  following  : 

I.  Primarily,  the  cerebellum  is  only  the  dorsal  part  of 


^  "Sum.  MBDIC4L  Rkoko,  April  to  Jiim,  1884. 
'  Ceretmin,  cerebellum,  and  axis  (or  Udimui). 
'  Dieaocphalon  (Wilder),  dentencephalon. 


the  wall  surrounding  the  anterior  part  of  the  cavity  of 
the  hind  brain  (fourth  ventricle). 

2.  The  ventral  part  of  this  wall  is  morphologically 
continuous  with  and  inseparable  from  the  posterior 
"  open  "  part  *  of  the  fourth  ventricle. 

3.  The  cephalic  portion  of  the  fourth  ventricle  is  dis- 
tinguished from  the  caudal  portion  only  by  the  fact  that 
in  the  former  the  roof — and  the  roof  alone — undergoes 
hypertrophy,  while  in  the  latter  it — and  it  alone — under- 
goes atrophy.  If  this  fact  is  to  constitute  a  discrimina- 
tion between  two  cerebral  segments,  then  the  closed, 
portion  of  the  oblongata  should  be  separated  firom  the 
open  portion. 

4.  There  is  at  no  time  an  indication  of  a  boundaiy  (of 
the  kind  found  with  other  ventricular  cavities  in  all  higher 
forms)  between  the  epicalia  and  metaccelia.  The  procag' 
iia  are  separated  from  the  diacoslia  by  a  constriction,  the 
p&rta  Monroi;  the  diacoelia  and  fourth  ventricle  are  de- 
marcated firom  the  mesocoelia  by  a  sudden  narrowing,' 
but  where  is  the  boundary  between  the  two  divisions 
which  Wilder  makes  of  our  old  familiar  fourth  ventricle  ? 
It  happens  to  widen  out  at  the  (imaginary)  boundary. 

5.  Dr.  Wilder  recognizes  the  necessity  of  finding  a 
ventral  part  of  his  epencephalic  segment,  and  believes 
to  have  found  it  in  the  pons.  The  term  "  pons  "  in  one 
sense  indicates  an  arbitrary  division  ;  in  another  it  is  used 
to  designate  only  the  (apparently)  transverse  fibre  mass 
which  is  thrown  across  the  brain-axis  like  a  belt  This 
is  not  a  commissural  mass,  however.  Nearly  all  its 
fibres  pass  to  the  crura  cerebri,  either  with  or  without 
ganglionic  intervention,  according  to  the  testimony  of 
Gratiolet,  Me)mert,  Vemicke,  and  Flechsig.  Morpho- 
logically they  are  heralded  in  lower  animals  by  arciform 
fibres  which  are  continuations  of  the  zonal  fibre  system 
common  to  the  entire  myelencephalon  of  reptiles  and 
birds.  There  is  henc^  no  support  to  be  derived  from 
the  existence  of  this  apparent  basilar  commissure  for 
Wilder's  designation.  This  objection  is  strengthened  by 
the  next 

6.  There  is  not  even  an  approximate  uniformity  in  the 
boundary  of  the  epencepkalon.  If  the  extent  of  the  cere- 
bellum be  taken  as  the  gauge,  it  is  almost  nil  in  meno- 
bronchus  and  extremely  large  in  man.  Homologous 
parts  of  the  ventricular  floor  fall  within  the  epicoilia  in 
man  and  without  in  reptiles.  If  the  extent  of  the  pons 
be  taken  as  a  guide,  then  this  segment  is  absent  in  rep- 
tiles and  birds,  it  is  a  narrow  belt  in  the  opossum, 
twice  as  wide  in  the  rabbit,  thrice  as  great  in  the  dog, 
five  times  as  great  in  the  ape,  and  six  times  as  wide 
(cephalo-caudad)  in  man. 

The  only  indication  of  a  coelian  monopoly  on  the  part 
of  the  cerebellum  is  the  tent-like  projection  of  the  fourth 
ventricle  into  the  fasiigium.  Indeed,  in  birds — like  the 
ostrich — ^it  is  a  closed  pond,  communicating  with  the 
fourth  ventricle  by  a  narrow  slitv  But  this  is  not  a  ven- 
tricular segment,  hvX  a  diverticulum^  Wke  the  primitive 
cavity  of  the  hypophysis  (pituitary  body)  or  the  conarium 
{epiphysis  or  pineal  gland).  I  think  this  comparison 
suggests  the  true  morphological  x/tf/«x  of  the  cerebellum. 

Respectfully, 

E.  C.  SprrzKA. 


Treatment  OF  Phlyctenular  Ophthalmia. — Dr.  H. 
Power  recommends  as  a  local  remedy  in  cases  of  phlyc- 
tenular ophthalmia  an  ointment  commonly  called  Pagen- 
stecher's,  which  is  a  combination  of  vaseline  with  bin- 
oxide  of  mercury,  in  proportions  var}'ing  from  one  to 
ten,  or  even  fifteen,  grains  to  the  ounce.  This  forms  a 
yellow  ointment,  whidi  in  the  milder  forms  gives  scarcely 
any  pain,  but  in  the  stronger  proves  sharply  irritating  to 
the  eye,  inducing  firee  lachrymation.  Dr.  Power  thinks 
that  this  preparation  may  be  regarded  as  a  specific  for 
corneal  ulcers. — Louisville  Medical  News. 

^  Whera  die  roof  loseajits  nervous  character  and  becomes  membranoos. 
*  Even  in  reptileB. 


112 


THE  MEDICAL  RECORD. 


[July  26, 1884 


^vmvi  ^jmns. 


Official  List  qf  Changes  in  the  Stations  and  DuiUs  cf  Officers 
serving  in  the  Medical  Departmsni^  United  States  Army, 
from  July  13  to  July  19,  1884. 

Wright,  J.  P.,  Major  and  Surgeon.  Assigned  to  duty 
as  Post  Surgeon,  San  Antonio,  Texas.  S.  O.  87,  par.  4, 
Headquarters  Department  of  Texas,  July  14,  1884. 

McElderry,  Henry,  Captain  and  Assistant  Surgeon. 
From  Department  of  the  Platte  to  Department  of  the 
East     S.  O.  165,  par.  12,  A.  G.  O.,  July  16,  1884. 

EwEN,  Clarence,  Captain  and  Assistant  Surgeon. 
Assigned  to  duty  as  Post  Surgeon,  Fort  Sidney,  Nebras- 
ka. S.  O.  58,  par.  8,  Headquarters  Department  of 
Platte,  July  11,  1884. 

Elbrey,  F.  W.,  Captain  and  Assistant  Surgeon.  Leave 
of  absence  still  further  extended  six  months  on  surgeon's 
certificate  of  disability.  S.  O.  161,  par.  6,  A.  G.  O., 
July  12,  1884. 

Wakeman,  Wm.  J.,  First  Lieutenant  and  Assistant 
Surgeon.  Relieved  from  duty  at  Fort  D.  A.  Russell, 
Wyo.,  and  assigned  to  duty  as  Post  Surgeon,  Fort  Wash- 
akie, Wyo.,  relieving  Assistant  Surgeon  Norton  Strong. 
S,  O.  58,  par.  9,  Headquarters  Department  of  Platte, 
July  II,  1884. 

Ewing,  Charles  B.,  appointed  to  be  Assistant  Sur- 
geon, with  the  rank  of  First  Lieutenant,  July  5,  1884, 
vice  Middleton,  promoted.  Memorandum,  A.  G.  O., 
July  14,  1884. 


W^t&ivxX  Itjems, 


CoMTAGious  Diseases — ^Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  July  19,  1884 : 


Week  Ending 


Gutff. 

July  12, 1884  . . 
July  19,  1884. . . 

Deaiks. 
July  12, 1884.  . 
July  19,  1884. . 


4 
3 


I 


187 
167 


The  Amorphous  Borate  of  Quinine  is  a  prepara- 
tion highly  recommended  by  Finkler  and  Prior,  who 
have  used  it  in  the  clinic  at  Bonn.  Its  advantages  are 
that  it  does  not  irritate  the  stomach,  and  that  it  has  a 
more  powerful  antiseptic  action  in  the  digestive  tube.  It 
is  used  in  about  the  same  doses  as  the  sulphate. 

Cerebral  An£miants  and  Hyper^miants. — Curci, 
experimenting  upon  dogs  by  trepanning  and  attaching  a 
uranometer,  finds  that  chloral,  chloroform,  ether,  paral- 
dehyde, and  quinine,  produce  cerebral  anasmia;  mor- 
phine and  nitrite  of  amyl,  hyperaemia.  Atropine  in 
small  doses  has  little  effect ;  in  larger  doses  it  is  rather 
an  an6miant. 

Chloroform  in  the  Treatment  of  Tape-worm. — 
Dr.  J.  G.  Brooks  writes  to  the  Medical  and  Surgical 
Reporter :  "  I  have  had  within  the  last  three  years  sev- 
erad  cases  of  tape-worm  to  treat,  and,  finding  such  strong 
objection  to  the  large  draught  of  medicines  in  ordinary 
use,  I  prescribed  the  following:  $•  Chloroform,  ex. 
male  fern,  aa  f  3  j.;  emul.  ol.  ricini  (50  per  cent.),  f  |  tij. 


M.  Sig. — All  to  be  taken  at  once  after  twenty-four  hours' 
fast  In  every  case  the  medicine  was  well  borne  and 
the  worm  expelled  entire.  In  two  cases  I  omitted  the 
male  fern,  and  the  result  was  the  same  as  when  the  latter 
drug  was  in  combination.  My  object  in  reporting  this 
treatment  is  to  induce  others  of  the  profession  to  try  the 
chloroform  and  report  results.  I  claim  for  this  agent  a 
specific  and  rational  action  as  an  adjuvant  in  the  expul- 
sion of  the  worm.  It  anaesthetizes  or  suspends  vitality, 
and  any  active  purge  during  anaesthesia  of  the  taenia  is 
all  that  is  requisite  to  expel  it.  I  earnestly  ask  those 
who  have  cases  to  try  the  chloroform,  or  chloroform  and 
male  fern,  as  above  prescribed,  and  report  results." 

In  the  Treatment  of  Sprains,  Dr.  Brinton,  in  the 
College  and  Clinical  Record^  recommends  that  the  limb 
is  to  be  put  into  a  vessel  of  ver)'  hot  water  immediately, 
boiling  water  being  added  as  it  can  be  borne,  and  kept 
immersed  for  twenty  minutes,  or  until  the  pain  ceases. 
Then  put  on  a  pretty  tight  bandage  and  order  rest. 
Sometimes  the  joint  can  be  used  in  twelve  hours.  If 
the  trouble  is  more  chronic,  apply  a  silicate  of  sodium 
dressing,  and  let  the  patient  walk  with  a  cane,  if  the 
ankle  be  the  joint  affected. 

The  Question  of  the  Feeding  of  Infants  has 
been  recently  discussed  in  the  British  Medical  Journal 
by  Drs.  Beatty  and  Davies.  Thtf  latter  gentleman  gives 
the  following  presentation  of  his  view  of  the  matter.  He 
sa^s :  ^*  Now,  as  the  food  we  are  at  variance  about  is 
milk  in  its  usual  state  from  the  cow,  or  condensed,  let  us 
see  how  we  stand.  Dr.  Beatty  recommends  one  part  of 
milk  to  three  of  water,  I  recommend  two  parts  of  milk 
to  one  of  water.  Now  let  us  take  the  composition  of 
milk,  and  then  judge  as  to  which  approximates  nearest  in 
strength  to  the  mother's. 

Woman.         Cow.         Abi. 

Casein  (cheesy  matter)  and  insolu- 
ble salts Z'ZS  4-55  1-70 

Fatty  matter 3.34  3.70  1.40 

Sugar  of  milk  and  soluble  salts. . .  3.77  5.35  6.40 

Water 89.54  86.40  90.50 


100.00  100.00  100.00 

From  this  analysis  it  will  be  seen  at  once  that  Dr. 
Beatty's  is  much  too  weak.  It  is  estimated  that  a  healthy 
woman  gives  three  pints  of  milk  in  the  twenty-four  hours; 
therefore  an  infant  should  have  at  least  a  quart  of  cow's 
milk  a  day,  as  mudi  must  of  necessity  be  wasted  by  giv- 
ing it  by  the  bottle,  and  I  know  of  no  reason,  nor  have  I 
ever  read  of  any,  which  shows  that  a  woman's  milk  is 
weaker  at  first  than  it  is  in  four  or  five  months  after  par- 
turition. Now,  with  regard  to  condensed  milk,  ^the 
First  Swiss  Brand,'  that  is,  the  unsweetened  milk  (the 
only  kind  that  should  be  used),  is  four  times  as  strong  as 
ordinary  milk  from  the  cow ;  therefore,  a  tin  would  be 
equivalent  to  a  quart  of  milk.  I  say  a  tin  a  day  is  about 
what  should  be  given,  diluted  with  five  times  its  bulk  of 
water.  Dr.  Beatty  says  he  orders  a  teaspoonful  (!)  to  a 
quarter  of  a  pint  of  water,  at  first,  and  says  infants  thrive 
on  it ;  that  may  be  his  experience,  I  regret  to  say  it  is 
not  mine/* 

Sodium  Iodide  instead  of  Potassium  Iodide. — 
Dr.  Jno.  D.  Mulhane,  of  Steubenville,  O.,  writes,  refering 
to  the  article  on  "  Sodium  Iodide,"  of  Dr.  Beig  (Medi- 
GAL  Record,  vol  xxv.,  p.  542) :  "  During  the  past  year, 
while  physician  to  Gould's  Tunnel  Panhandle  Railway, 
I  had  under  my  care  four  hundred  men,  white  and 
colored.  In  this  class  of  fellows  you  find  syphilis  in  all 
its  forms.  At  first  I  used  potassium  iodide,  but  noticing 
that  the  late  lamented  Gross,  in  *  Surgery  '  (voL  i.,  p.  338, 
1872)  was  y^ry  partial  to  sodium  iodide,  I  used  it  in  one 
hundred  anid  seven  cases,  and  in  not  one  did  it  produce 
that  dryness  of  air-passages  which  follows  potassium 
when  pushed.  I  heartily  agree  with  Dr.  Beig.  No 
gastro-intestinal  irritation  in  a  single  case." 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  5 


New  York,  August  2,  1884 


Whole  No.  717 


©riflitml  ^rticljes. 


ADDRESS  ON  PHYSIOLOGY, 

Dblivbred  at  the  Annual  Meeting  of  the  Brit- 
ish Medical  Association,  July  29,  1884. 

By  PETER  REDFERN,  M.D.  Lon.,  F.R.C.S.L., 

rSOnSSOR  of  anatomy  and  physiology  XN  QURKN's  COLLBCB,    BHX.FAST. 

(Special  for  Thb  Mbdical  Rbcord.) 

Ur,  President  and  Gentlemen  of  the  British  Medical 
Amdation  :  I  value  very  much  the  honor  of  having 
been  selected  to  give  the  address  on  physiology  and  I 
thank  you  warmly  for  the  mark  of  your  confidence  which 
it^implies. 

The  great  problems  of  life  have  in  all  time  had  a  pro- 
iband  influence  upon  the  heart  and  mind  of  man.  What- 
ever concerns  the  prolongation  of  life,  or  the  increase  of 
the  capadty  for  enjoying  it,  the  prevention  or  cure  of 
tiwse  modified  vital  actions  which  we  know  as  disease 
has  always  interested  the  mass  of  mankind.  Hence  the 
mission  of  medical  men — ^as  extensive  as  humanity, 
whatever  form  it  takes — uninfluenced  by  age,  or  sex,  or 
ountiy — succoring  alike  the  orphan,  the  criminal,  the 
ratuous,  the  poor,  and  the  rich.  The  medical  man  is 
die  true  fiiend  of  all  within  his  reach  ;  he  advises,  in- 
stnicts,  befriends  all  alike. 

There  is  no  one  to  whom  accurate  and  ikicessant  ob- 
serration  is  so  essential.  His  first  step  is  to  observe  and 
record  all  the  healthy  phenomena  of  life ;  it  is  his  con- 
stant care  to  secure  the  most  fitting  conditions  for  their 
Bercise;  and  his  last  effort  is  to  note  how  certainly 
ieir  continued  action  brings  about  their  own  extinction, 
and  how  often  they  are  suddenly  arrested  in  their  course 
hf  disease. 

The  delicate  adjustments  of  vital  operations  and  the 
unstable  physical  and  •  chemical  equilibrium  of  living 
structures  present  such  difficulties  to  the  physiologist 
{hat  thousands  of  years  of  the  world's  history  had  passed 
before  we  had  learned  a  single  fundamental  doctrine  ap- 
plicable to  all  life  on  the  globe.  Yet  I  doubt  if  as  great 
progress  has  been  made  in  any  science  as  in  physiology 
dnimg  the  past  fifty  years,  or  if  such  an  amount  of  labor 
-has  been  expended  in  the  same  time  on  any  subject  as 
has  been  devoted  to  the  study  of  physiology  in  the  last 
fiarter  oi  a  century.  Still  all  we  now  know  may  appear 
very  insignificant  in  the  estimation  of  our  successors  of 
the  next  generation. 

Every  step  in  physiology  concerns  life  and  health; 
teefore  each  must  be  made  as  secure  as  possible.  1 
tfunk  nothing  has  given  as  great  confidence  and  security 
&  die  advance  of  physiology  as  the  demonstration  that 
d  living  matter  has  been  derived  from  previously  living 
Htter  of  its  own  kind,  and  that  all  living  beings  and 
tissues  have  originated  from  fragments  of  previously 
beings  or  tissues,  which,  when  detached,  carried 
properties  of  their  parents  with  them. 

It  is  quite  true  that  living  bodies  are  continually  in- 
fcenced  and  altered  by  external  conditions ;  but  it  is 
tin  true  that  conditions  at  least  as  potent  tend  to  their 
Kton  to  their  original  state.  The  changes  which  a  par- 
fadar  mode  of  life  may  effect  in  the  highest  type  of 
in&g  beings  may  be  such  as  to  require  three  generations 

iDnuLke  a  glass-blower ;  but  it  is  not  probable  that  his 


children  would  care  to  preserve  the  advantages  which 
they  had  derived  by  inheritance  from  their  parent's  father 
and  grandfather. 

The  formed  materials  of  our  tissues  differ  widely  from 
the  original  protoplasm  to  which  they  owe  their  origin  ; 
but  some  of  that  protoplasm  remains  in  each,  and  still 
possesses  powers  of  reproduction,  which,  in  many  in- 
stances, are  no  less  startling  because  of  the  character 
than  of  the  quantity  of  the  tissue  produced  in  a  given 
time.  The  colossal  increase  in  size,  no  less  than  the 
increase  in  number,  of  the  muscular  fibres  of  the  uterus 
required  to  raise  the  standard  weight  of  the  adult  organ 
from  one  and  a  half  ounces  to  three  pounds,  is  only  par- 
alleled by  the  still  more  rapid  reduction  in  two  or  three 
weeks  of  the  same  organ  from  three  pounds  in  weight  to 
three  ounces.  This  happens  in  an  organ  which  is  often 
more  or  less  dormant  for  years  together ;  but  in  the  con- 
tinually acting  diaphragm,  the  presence  of  an  unusual 
number  of  protoplasmic  corpuscles  in  each  fibre  points 
to  the  greater  and  more  persistent  activity  of  the  change 
which  takes  place  there.  Observe,  in  comparison  with 
its  cause,  the  vastness  of  the  change  produced  in  the 
mode  of  nutrition  of  the  uterus,  when  an  ovum  only 
y^th  of  an  inch  in  size  has  come  into  contact  with  a 
still  smaller  spermatozoon  ;  and  the  not  less  remarkable 
change  when  this  ovum  leaves  the  uterus.  The  estab- 
lishment of  different  physiological  relations  has  been  at- 
tended in  the  first  instance  by  deposition  and  formation 
of  tissue  ;  in  the  other,  by  its  disintegration  and  removal. 

Changes  of  external  conditions  produce  as  remarkable 
results.  Mr.  Ward  found  ill-fed  plants  of  the  common 
centaury  (Erythrc3ea  Centaurium)  only  half  an  inch  high, 
with  one  flower,  at  no  great  distance  from  better  fed  ones 
four  or  five  feet  high,  covered  with  hundreds  of  flowers. 
Without  other  difference  than  greater  looseness  of  the 
texture  of  the  soil  I  had  plants  of  the  common  rape 
(Brassica  napus)  between  five  and  six  feet  high,  freely 
branched  everywhere,  and  carrying  leaves  as  large  as 
ordinary  dishes,  as  contrasted  with  others  close  by,  only 
fifteen  inches  high,  but  little  branched,  and  having  few 
linear  leaves  only  about  an  inch  long.  And  everyone  is 
familiar  with  the  marvellous  change  wrought  upon  the 
hive  bee  when,  from  being  fed  on  royal  jelly  instead  of  an 
ordinary  bee-bread,  it  becomes  a  queen.  Yet  these 
naked-eye  evidences  of  the  influence  upon  vital  activity 
of  a  change  in  surrounding  circumstances  are  insignificant 
in  importance  when  compared  with  those  of  which  the 
results  are  witnessed  daily  in  medical  practice. 

Dr.  Williams  showed  that  when  a  drop  of  weak  solu- 
tion of  capsicum  is  applied  to  the  web  of  a  frog's  foot,, 
dilatation  of  the  arteries  and  capillaries  takes  place  and 
more  blood  circulates  through  the  spot  in  a  given  time 
than  before,  and  that  from  this  condition  recovery  may 
take  place,  and  the  experiment  be  repeated  time  after 
time  on  the  same  part  But  if  the  solution  be  stronger 
recovery  will  not  occur,  and  the  increased  rapidity  of 
circulation  will  give  place  to  slowing  and  stagnation.  In 
the  first  instance  the  life  of  the  vessels  was  affected  and 
their  contractility  impaired  transitorily,  but  the  stronger 
solution  destroyed  their  contractility  more  completely 
and  produced  the  phenomena  of  inflammation,  conges- 
tion,  exudation,  and  stasis.  No  matter  by  what  external 
means  the  life  of  the  vessel  is  affected,  the  same  result 
follows.  And  if  the  injury  be  inflicted  firom  within  by 
adding  some  irritant  to  the  circulating  fluid  the  effect  is 
still  the  same. 


114 


THE   MEDICAL  RECORD. 


[August  2,  1884. 


Mr.  Lister  demonstrated,  in  a  series  of  beautifully-con- 
trived experiments,  the  delicacy  of  the  relations  between 
the  walls  of  the  blood-vessels  and  the  circulating  blood — 
that  injury  of  the  wall  of  a  vessel  causes  arrest  of  the 
white  corpuscles  on  the  injured  part,  with  coagulation  of 
the  blood  ;  and  if  the  injury  be  considerable,  it  will  cause 
complete  obstruction  to  the  circulation.  Disintegration 
of  the  white  corpuscles  takes  place,  and  acts  as  an  effici- 
ent cause  of  the  coagulation  and  stoppage. 

On  the  maintenance  of  this  nice  balance  of  the  rela- 
tions between  the  blood  and  the  tissue  over  which  it 
flows  depends  the  issue  whether  the  blood  shall  continue 
to  flow  or  not. 

The  rupture  of  the  internal  coat  of  a  vessel,  or  the  al- 
teration of  the  lining  endothelium  by  endocarditis,  causes 
arrest  and  disintegration  of  white  corpuscles  at  the  spot. 
.  Consequently,  depositions  of  fibrin  or  the  formation  of 
thrombi  on  the  valves  of  the  heart  are  attendant  phe- 
nomena on  inflammation  of  the  endocardium. 

And  Cohnheim  found  that  stopping  the  circulation  for 
from  thirty-six  to  sixty  hours,  through  particular  vessels 
in  a  frog,  and  then  allowing  the  circulation  to  go  on 
again,  was  attended  by  such  exudation  as  occurs  in  in- 
flammation. The  walls  of  the  vessels  had  suffered  in- 
jury from  the  temporary  arrest  of  the  circulation,  their 
elements  seemed  to  have  been  loosened,  and  exudation 
of  certain  of  their  contents  took  place. 

It  is  important  to  note  that  this  is  not  a  mere  passive 
transudation,  it  is  attended  with  an  active  movement  of 
the  living  corpuscles  through  the  injured  wall,  a  move- 
ment which  does  not  happen  in  the  instance  of  the  mes- 
entery to  which  solution  of  sodium  chloride  of  double 
the  normal  strength,  which  stops  the  amoeboid  move- 
ments of  these  corpuscles  out  of  the  body,  has  been  ap- 
plied. An  inflammatory  exudation  is  readily  distinguish- 
able from  the  transudation  of  mere  engorgement  by 
being  richer  in  albumen  and  corpuscles  than  it,  and  by 
coagulating  more  readily. 

Dr.  Burdon-Sanderson,  in  his  admirable  statement  of 
the  results  of  his  own  observations  and  in  reviewing  our 
present  knowledge  of  inflammation,  has  called  attention 
to  the  great  accuracy  of  Sir  William  Bowman's  early  ob- 
servations on  keratitis,  and  has  pointed  out  that  not  only 
do  corpuscular  elements  migrate  into  injured  spots  of 
the  cornea,  but  that  they  accumulate  upon  and  within 
pieces  of  dead  membrane  or  other  tissue  inserted  into 
the  peritoneal  cavity.  And  Dr.  J.  Hamilton  found  that 
they  so  completely  fill  the  cavities  of  pieces  of  prepared 
and  engrafted  sponge  that  it  soon  ceases  to  be  visible. 
Dr.  Sanderson  has  expressed  the  difficulty  of  maintain- 
ing that  the  migration  of  corpuscles  is  in  such  instances 
due  to  an  increased  attraction  between  them  and  the 
tissues,  and  he  concludes  that  we  are  coming  back  to  the 
notions  of  John  Hunter,  who  accounted  for  the  inflam- 
matory blush  by  referring  it  to  the  action  of  the  vessels. 

On  the  other  hand,  it  may  be  suggested  that  the 
changed  conditions  have  diminished  the  restraining  in- 
fluence of  the  walls  of  the  vessels  and  stimulated  the  cor- 
puscles to  more  active  migration  than  ordinary. 

The  interest  and  importance  of  the  relations  of  the 
circulating  fluids  to  the  elements  of  the  animal  tissues 
demands  a  further  consideration  of  them. 

The  structure  and  action  of  the  supply  vessels  of  any 
part  are  doubtless  very  important,  but  they  can  scarcely 
equal  in  importance  the  relations  of  the  tissue  and  blood 
elements  where  these  lie  quietly  in  contact,  and  mutually 
influence  each  other. 

One  can  scarcely  exaggerate  the  importance  of  the 
observation  that  the  pressure  impelling  the  secreted  fluid 
outward  in  a  salivary  duct  is  twice  as  great  as  that  pro- 
pelling the  blood  in  the  carotid  artery,  from  which  that 
gland  is  supplied,  and  that  a  large  amount  of  secretion 
is  discharged  by  a  salivary  gland,  on  stimulation  of  its 
nerve,  after  the  circulation  of  blood  has  been  altogether 
cut  off  from  it.  In  like  manner,  at  the  instance  of  a 
nervous  impulse,  a  muscle  similarly  withdrawn  from  the 


circulating  current  contracts  and  gives  out  cafbonic 
acid  and  sarcolactic  acid,  neither  of  which  was  free  in 
it  before  the  contraction  took  place.  And  in  the  gastric 
glands,  the  pancreas,  and  possibly  in  all  secreting  glands, 
the  constituents  of  the  secretions  are  slowly  abstracted 
from  the  blood  and  stored  in  some  form  of  zymogen 
until  a  nervous  impulse  suddenly  causes  their  transfor- 
mation into  the  active  principles  of  the  secretion  and  its 
discharge. 

Thus  we  localize  the  real  laboratory  of  the  organism— 
the  place  where  the  work  of  the  body  is  done — the  spot 
whence  nervous  impulses  emanate — where  motion  re- 
sults from  chemical  and  vital  changes — where  the  powers 
operate  which  regulate  and  produce  secretions,  excre- 
tions, nutrition,  regeneration,  and  reproduction. 

It  will  be  admitted  that  the  simplest  mass  of  proto- 
plasm, whether  plant  or  animal,  selects  all  it  needs  for 
the  varied  purposes  of  its  life  from  the  more  or  less  fluid 
matters  within  its  reach ;  and,  in  exactly  the  same  way, 
the  tissues  of  our  bodies  select  what  they  need  from  the 
fluid  plasma  in  which  they  are  continually  bathed.  The 
vessels  supply  a  larger  or  smaller  quantity  of  this  fluid 
as  the  demands  of  the  tissues  are  greater  or  less  at  one 
time  than  at  another ;  but  it  is  the  business  of  each  tissue 
to  select,  both  as  to  character  and  amount,  all  it  re- 
quires, and  in  this  selection,  no  less  than  in  the  use 
it  makes  of  the  materials  it  has  selected,  the  tissue  can 
only  be  very  indirectly  aided  by  the  blood-vessels. 

The  anatomical  relations  of  the  tissue  elements  to  the 
lymph  spaces,  by  means  of  which  they  are  continually 
bathed  in  lymph,  are  very  interesting,  and  have  been  ad- 
mirably described  and  illustrated  by  Dr.  Klein  in  his 
"Anatomy  of  the  Lymphatic  System"  and  "Adas  of 
Histology.'*  Dr.  Curnow  has  given  an  excellent  account 
of  the  history  of  the  acquisition  of  our  knowledge  of  the 
lymphatic  system  in  the  Gulstonian  Lectures  for  1879, 
published  in  The  Lancet  Von  Recklinghausen  led  the 
way,  and  so  many  accurate  observers  in  different  coun- 
tries have  followed  him  that  we  now  stand  on  very  safe 
ground. 

The  result  has  shown  that  the  acini,  or  the  tubes  of 
glands,  the  bundles  of  fibres  of  tendons,  the  layers  of  the 
cornea,  fasciculi  of  muscles,  and  funiculi  of  nerves,  are 
in  relation  with  lymph  spaces,  or  vessels  more  or  less 
completely  lined  by  endothelial  cells,  and  occupied  by 
lymph  containing  amoeboid  corpuscles  in  variable  num- 
bers. These  Dr.  Klein  has  shown  to  belong  to  the  same 
system  as  the  spaces  between  the  fibres  and  bundles  of 
fibres  of  areolar  tissue,  which  contain  here  and  there 
flattened  and  branched  endothelial  or  connective  tissue 
cells  folded  over  the  bundles,  which  are  themselves  con- 
tinually bathed  in  lymph  containing  amoeboid  corpuscles. 
Similar  spaces  under  the  mucous  membrane  of  the  ali- 
mentary canal  or  air-passages  are  continuous  with  the 
cement  substance  between  the  epithelial  cells,  where 
also  branched  connective-tissue  cells  occur,  together  with 
occasional  amoeboid  corpuscles.  All  such  spaces  com- 
municate directly  with  large  lymph  canals,  immediately 
succeeded  by  irregularly  dilated  lymphatic  vessels  fur- 
nished with  valves. 

The  immediate  effect  of  medicines  introduced  ender- 
mically  is  abundant  proof  of  the  rapid  and  free  com- 
munication of  the  lymph  of  the  spaces  of  areolar  tissue 
with  the  current  of  the  blood,  while,  if  Dr.  Creighton's 
observations  on  the  absorption  of  fat  from  the  intestines 
be  confirmed,  we  shall  have  learned  that  the  emulsified 
fat  of  chyle  passes  through  the  cement  spaces  of  the 
intestinal  epithelium  into  the  lacteal  and  mesenteric 
glands,  the  epithelium  itself  discharging  the  function  of 
secretion. 

But  there  are  much  larger  reservoirs  of  lymph  than  the 
spaces  of  connective  tissue,  tendon,  and  cornea.  The 
great  lymphatic  sac  of  the  frog,  the  serous  and  synovial 
cavities,  and  the  sheaths  of  tendons  of  mammals  and  man 
are  similar  spaces.  Von  Recklinghausen  was  the  firs^ 
to  witness  the  passage  of  milk  and  other  fluids  contain- 


August  2,  1884.] 


THE  MEDICAL  RECORD. 


115 


in£  visible  particles  through  the  stomata  of  the  peri- 
toneum covering  the  tendon  of  the  diaphragm  into  the 
hniphatic  vessels,  and  the  disappearance  of  fluids  from 
tiie  peritoneal  sac  by  this  means.  You  will  all  call  to 
mind  many  instances  of  rapid  disappearance  of  recent 
pleuritic  and  peritoneal  effusions ;  others,  where  such 
efiiisions  have  remained  undiminished  in  amount  for 
weeks  and  months,  and  some  in  which  the  effused  fluid 
ifia  a  time  assumed  all  the  characters  of  pus.  Coagu- 
lated blood  does  not  disappear  from  the  peritoneal 
canty,  but  defibrinated  blood  is  absorbed  and  its  corpus- 
cles continue  to  live  in  the  circulating  blood. 

Ladwig  and  Schweigger-Seidel  have  pointed  out  that 
the  respiratory  movements  are  the  chief  cause  of  the  en- 
trance of  fluids  into  the  lymphatic  spaces  through  the 
stomata  of  the  peritoneum,  and  that  during  the  descent 
of  the  diaphragm  l)rmph  is  drawn  into  the  spaces  between 
the  tendon  bundles  by  their  expansion,  and  pressed  on 
at  the  same  time  in  the  pleural  lymphatics  furnished 
with  valves,  while  during  the  ascent  of  the  diaphragm, 
exactly  the  opposite  action  takes  place,  the  diaphragm 
thus  playing  the  part  of  a  pump. 

The  pleura  of  the  intercostal  spaces  is  also  provided 
with  stomata  and  is  similarly  related  to  lymphatic  vessels, 
and  as  there  is  an  arrangement  of  a  similar  kind  on  the 
sariaces  and  in  the  substance  of  all  fasciae  and  tendon 
^aths,  it  is  not  improbable  that  the  connections  of  a 
jvge  number  of  muscles  with  fasciae  rather  than  bones 
jBfvcs  the  same  purpose.  How  much  of  the  pleasure 
derived  from  muscular  exertion  depends  upon  the  pro- 
motion of  the  circulation  of  lymph  about  all  these  parts, 
ind  upon  their  consequent  invigoration,  we  may  never 
le  able  to  estimate,  but  no  one  can  question  the  impor- 
iBce  even  in  the  limbs  of  a  free  circulation  of  lymph. 
Let  us  now  return  to  the  contents  of  these  spaces, 
lebear  in  mind  that  epithelial  cells  are  masses  of  proto- 
ibsm  variously  modified  for  secretion,  protection,  or  for 
itering  into  the  construction  of  the  terminal  organs  of 
k  nerves  of  special  sense,  and  that  between  epithelial 
^  whether  on  the  skin,  the  cornea,  or  on  mucous 
lembranes,  there  are  spaces  occupied  by  semi-fluid 
ment,  with  branched  connective-tissue  coipuscles,  and 
ioeboid  or  white  blood-cells.  We  trace  these  cement 
Bces  onward  and  And  them  continuous  with  the  con- 
Ktive-tissue  spaces  under  their  respective  membranes 
nd  with  lymphatic  vessels.  In  the  different  spaces  the 
Dotained  corpuscles  vary  greatly  in  number,  but  a  food- 
ipply  is  always  afforded  them  by  l^ood- vessels  in  pro- 
ortion  to  their  number. 

Under  extensive  tracts  of  the  mucous  membrane  of  the 

imentary  canal  and  respiratory  organs,  very  notably  in 

be  sabstance  of  villi  and  around  Lieberkuhnian  follicles 

the  intestine,  the  spaces  are  crowded  with  amoeboid 

lymph  corpuscles  forming  adenoid  tissue,  or  when 

Bsscs  of  such  tissue  accumulate  in  more  or  less  spheri- 

ll  or  pear-shaped  blocks  they  constitute  solitary  glands 

the  glands  of  the  patches  of  Peyer.     All  such  parts 

!  supplied  very  freely  with  capillary  blood-vessels,  and 

Riicke  demonstrated  many  years  ago,  their  spaces 

Rctly  communicate  with  unusually  large  and  numerous 

iphatic  or  lacteal  vessels.     The  lacteals  become  al- 

st  inunediately  connected  with  the  largest  group  of 

Bphatic  glands  in  the  body.    The  muscular  and  fibrous 

ill  of  the  vessel  opens  out,  and  becoming  greatly  in- 

ttsed  m  amount  fonus   the  capsule  and  trabeculae, 

"e  the  cell  elements  of  the  connective  tissue  forms 

framework  of  the  adenoid  mass  we  call  lymphatic 

kL    The  substance  is  composed  of  lymphoid  cor- 

Bdes  multiplying  with  a  rapidity  which  is  measured  by 

food-supply  from  capillary  blood-vessels  and   the 

ig  stream  of  chyle ;  while  their  detachment  is  in 

^portion  to  the  amount  of  distention  by  passing  chyle. 

^greater  the  amount  of  chyle,  the  greater  is  the  num- 

of  corpuscles  added  to  it  as  it  passes,  each  corpuscle 

Ig  derived  both  in  substance  and  properties  from  a 

**'*<asting  one,   or,   as  in  the  original  development, 


from   the  differentiated  protoplasm  of  the   endothelial 
cells. 

Dr.  Klein  has  described  small  cells  which  bound  the 
stomata  of  serous  -membranes,  cover  the  surface  near  the 
stomata,  and  often  extend  along  considerable  tracts  of 
their  surface.  These  are  smaller  than  the  ordinary  endo- 
thelial cells  and  germinate  freely  under  ordinary  healthy 
conditions,  but  in  such  unhealthy  states  as  are  induced 
by  the  presence  of  pieces  of  gutta-percha  or  irritating 
substances  injected  into  the  peritoneal  cavity,  they 
germinate  with  great  rapidity  and  form  large  villous  pro- 
jections on  the  surface  of  the  membrane,  the  newly-pro- 
duced cells  falling  into  the  cavity  or  presenting  themselves 
in  large  numbers  in  the  adjacent  lymphatic  vessels. 

Thus,  in  the  same  way  as  in  lymphatic  and  other  blood- 
forming  glands,  white  corpuscles  of  the  blood  are  con- 
tinually formed  and  thrown  off  into  the  stream  of  chyle 
or  lymph,  so  under  both  normal  and  abnormal  circum- 
stances the  cells  bordering  the  stomata  and  covering 
parts  of  the  surfaces  of  serous  membranes  multiply 
rapidly,  while  in  inflammation  not  only  these  lymphoid 
cells,  but  the  branched  cells  of  the  matrix  also  undergo 
very  active  proliferation.  The  natural  food-supply  of 
such  cells  is  derived  from  the  blood,  the  amount  and 
rapidity  of  circulation  of  which  is  largely  increased  in 
some  stages  of  inflammation. 

I  now  ask  your  attention  to  the  structural  relations  of 
the  walls  of  blood-vessels  to  the  tissue  elements.  The 
most  cursory  examination  of  blood-glands,  such  for  in- 
stance as  the  spleen  and  the  red  marrow  of  bones,  shows 
an  important  adaptation  of  these  parts  to  each  other. 
Ordinary  capillaries,  which  are  really  little  more  than 
spaces  between  the  elements  of  tissues  lined  by  endo- 
thelial cells  loosely  cemented  together  at  their  edges, 
have  frequently  sinuous,  spindle-shaped,  or  angular  dila- 
tations upon  them,  while  their  walls  have  projecting  pro- 
cesses directly  continuous  with  the  branched  connective- 
tissue  corpuscles  of  the  adjacent  parts,  a  connection  which 
shows  the  close  similarity  of  the  lumen  of  the  vessel  to 
the  spaces  of  areolar  tissue,  while  the  endothelial  cells 
of  the  vessel  correspond  to  the  less  numerous  but  simi- 
larly flattened  endothelial  cells  of  the  spaces,  and  to 
tendon  and  corneal  corpuscles,  which  cover  in  an  equally 
sparing  manner  their  respective  tendon  or  corneal  spaces. 
Indeed,  the  whole  lymphatic  system,  with  its  lymph  cana- 
licular spaces  and  its  more  definitely  walled  vessels,  is 
neither  a  new  nor  an  added  system,  but  a  part,  and  a 
most  important  part,  of  the  general  vascular  system  of 
the  body. 

If  we  trace  a  small  artery  in  the  spleen,  we  see  the 
tissue  of  its  wall  opened  out  into  spaces  occupied  by 
lymphoid  cells,  a  veritable  mass  of  adenoid  tissue  involv- 
ing the  whole  or  part  of  the  circumference  of  the  vessel, 
and  when  at  length  the  vessel  ends,  it  empties  its  blood 
into  the  spaces  of  the  pulp  bounded  and  supported  by 
the  flattened,  branched,  endothelial  elements  of  the  walls 
the  commencing  veins.  Where  the  adenoid  masses,  the 
Malpighian  corpuscles  of  the  walls  of  the  arteries  abut 
upon  the  pulp  tissue  there  is  no  separation,  the  elements 
of  the  adenoid  reticulum  and  those  of  the  walls  of  the 
sinuses  being  continuous,  while  the  lymphoid  cells  of  the 
adenoid  tissue  are  free  to  mix  with  the  venous  blood  in 
the  sinuses.  Here,  as  in  the  case  of  the  lymphatic  glands, 
the  organ  is  subjected  to  great  distention  after  the  ab- 
sorption of  food,  which  not  only  leads  to  the  formation 
and  separation  of  large  numbers  of  new  lymphoid  ele- 
ments, but  at  the  same  time  the  cellular  protoplasmic 
elements  of  the  venous  sinuses  become  very  active,  take 
up  old  colored  corpuscles,  break  them  down,  and  set  free 
their  variously  oxidated  remains  into  the  blood  stream. 
The  vascular  arrangements  of  the  spleen,  at  the  same 
time  as  they  tend  to  retard  the  flow  of  the  blood,  are  no 
doubt  highly  advantageous  for  the  completion  of  the 
changes  which  the  blood  undergoes  in  the  organ,  while 
the  necessarily  tardy  flow  of  the  blood  is  no  doubt  com- 
pensated by  the  large  size  of  both  the  artery  and  the 


Il6 


THE  MEDICAL  RECORD. 


[August  2,  1884. 


vein,  and  the  loss  of  force  by  the  rhythmical  contractions 
of  the  organ  so  beautifully  demonstrated  by  Dr.  C.  S. 
Roy.  Lymphatic  glands  also  have  a  muscular  capsule 
and  muscular  trabeculse,  but  as  yet  we  have  no  evidence 
of  their  having  rhythmical  contractions. 

I  cannot  pass  without  mention  the  largest  living  mass 
of  protoplasm  in  the  body — the  liver — at  one  period 
employed  in  the.  production  of  blood-corpuscles,  and 
then  half  the  weight  of  the  body.  Originally  formed 
upon  the  vitelline  veins,  and  subsequently  transferred  to 
the  umbilical,  and  then  to  the  portal  vein,  as  each  in 
turn  becomes  the  recipient  of  the  food  supplies,  there  can 
be  no  doubt  that  while  its  function  is  mainly  to  make 
and  to  maintain  the  blood,  its  methods  of  action  still  in- 
volve great  physiological  secrets. 

From  the  preceding  considerations  it  is  plain  that  at 
certain  parts  of  the  circulating  system  for  lymph  and 
blood,  lymphoid  or  white  blood-corpuscles  are  produced 
in  adenoid  tissue  from  pre-existing  corpuscles  at  a  defi- 
nite rate.  If  Quincke  be  correct  in  his  supposition,  that 
the  duration  of  the  functional  activity  of  red  blood-cor- 
puscles is  not  longer  than  two  or  three  weeks,  we  have 
in  this  a  measure  of  the  required  productive  capacity, 
for  in  healthy  conditions  a  balance  of  the  absolute  and 
relative  numbers  of  the  corpuscles  is  very  accurately 
maintained. 

But  this  does  not  always  happen.  My  late  esteemed 
teacher  and  friend,  Dr.  Hughes  Bennett,  in  his  original 
description  of  leucocythemia,  pointed  out  that  an  amaz- 
ing relative  increase  of  white  in  relation  to  the  red  cor- 
puscles of  the  blood  occurs  in  connection  with  enlarge- 
ment of  various  of  the  blood-forming  organs,  and  the 
disease  is  now  universally  recognized.  In  the  second 
case,  which  came  under  the  notice  of  Dr.  Bennett,  I  had 
the  pleasure  of  making  the  examination,  and  of  record- 
ing and  sketching  the  microscopical  characters  of  the 
blood  in  the  Pathological  Reports  of  the  Royal  Infirmary 
of  Edinburgh.  •  In  that  case  the  spleen,  liver,  and  intes- 
tinal glands  were  all  enlarged. 

In  this  disease  there  is  a  greatly  increased  production 
of  lymphoid  cells  in  situations  where  there  is  abundance 
of  nutritive  material,  and  this  increased  formation  of  cor- 
puscles is  possibly  attended  by  a  conversion  of  fewer 
white  into  red  blood-corpuscles  than  ordinary,  thus 
greatly  increasing  their  numerical  disproportion. 

As  lymphoid  cells  can  also  be  produced  in  large  num- 
bers in  and  near  the  stomata,  and  on  the  surface  of  se- 
rous membranes,  it  is  probably  from  such  sources  that 
the  pus  corpuscles  of  empyema  and  peritoneal  effusions 
arise.  And  it  may  be  asked  whether  the  amoeboid  cells, 
which  migrate  through  the  walls  of  the  blood-vessels  on 
the  onset  of  inflammation,  possess  the  power  of  multiply- 
ing on  surfaces  which  are  now  supplied  with  a  largely 
increased  amount  of  blood. 

This  is  improbable  for  many  reasons.  Actual  obser- 
vation of  such  multiplication  has  not  yet  been  satisfac- 
torily obtained.  Dr.  J.  Hamilton,  in  the  record  of  his 
very  interesting  observations  on  the  healing  of  ulcers 
and  sponge-grafting,  says  that  he  has  carefully  watched 
the  exuded  leucocytes,  and  has  never  seen  them  get 
larger,  either  by  over-nutrition  or  coalescence.  Ranvier, 
who  thinks  it  probable  that  lymph  cells  are  connective 
tissue  cells  set  free  from  adenoid  tissue,  believes  that 
they  will  neither  move  nor  multiply,  except  when  freely 
supplied  with  oxygen  ;  that  the  free  supply  of  oxygen- 
ated blood  by  the  capillaries  of  lymphatic  and  other 
blood  glands,  is  the  means  of  their  multiplication,  and 
that  the  absence  of  oxygen  in  the  lymphatic  vessels 
stops  it.  He  sees  in  the  rapidity  of  the  circulation  of 
blood  an  explanation  of  their  migrating  in  small  num- 
bers only  in  health,  while  on  the  slowing  or  arrest  of  the 
circulation  in  inflammation  they  migrate  in  large  num- 
bers, and  getting  beyond  the  reach  of  the  supply  of  oxy- 
gen disintegrate  and  cause  coagulation  of  the  plasma. 
He  points  to  the  experiment  of  introducing  fragments  of 
phosphorus  under  the  skin,  without  arousing  inflamma- 


tion and  migration  of  leucocytes,  as  indicating  that  the 
phosphorus  has  taken  up  all  the  oxygen  present,  and  de- 
stroyed the  amoeboid  movement  necessary  for  migration, 
and  thinks  that  the  effect  of  cold  in  checking  exudation 
is  due  to  a  similar  action.  Whatever  the  mfluence  of 
oxygen  on  the  manifestation  of  the  vital  movement  of 
lymphoid  corpuscles,  it  is  certain  that  lymph  differs 
widely  from  blood  in  containing  a  mere  trace  of  oxygen. 

In  the  formation  of  an  acute  abscess,  the  part  is  hot, 
painful,  and  swelled,  exudation  and  coagulation  of  the 
exuded  matter  occur  with  migration  of  leucocytes 
through  the  vascular  walls ;  the  pain  becomes  more  se- 
vere and  throbbing,  and  the  heat  greater  than  before ; 
next  day  there  is  mdistinct  fluctuation  from  the  formation 
of  pus,  and  from  this  time  the  pain  and  heat  lessen,  and 
the  matter  makes  its  way  by  softening  and  degeneration 
to  the  surface.  The  greater  heat  and  pain  preceding 
the  formation  of  pus  indicate  greater  distention  of  the 
vessels,  and  greatly  increased  exudation  ;  or  that  the 
larger  supply  of  blood  which  increased  the  pain  and  ten- 
sion had  furnished  the  food  for  the  more  rapid  generation 
of  l)anphoid  corpuscles. 

When  in  diffuse  phlegmon  punctures  are  made  one 
day  and  discharge  thin  serous  fluid,  and  the  next  day  the 
whole  areolar  tissue  is  distended  with  pus,  there  is  little 
room  for  doubt  that  a  rapid  generation  of  lymphoid  cor- 
puscles has  taken  place  at  that  very  part  and  produced 
the  pus.  If  this  happen  in  one  instance,  it  is  probable 
that  in  other  cases,  too,  pus  is  either  formed  by  rapid 
proliferation  of  connective-tissue  corpuscles,  or  that  it 
is  the  result  of  rapid  generation  of  corpuscles  from  those 
which  first  migrated,  and  that  the  primary  cause  of  this 
is  an  increase  of  the  normal  attraction  of  the  tissue  for 
the  nutritive  matters  of  the  blood,  whereby  the  lymph 
stream  flows  more  slowly  and  the  corpuscles  drag  lazfly 
along  the  wall,  then  penetrate  it  and  escape  with  the 
plasma  in  large  amount  at  a  time  when  the  cement  be- 
tween the  endothelial  cells  has  softened,  and  the  spaces 
occupied  by  it  have  become  widened. 

But  whatever  be  the  cause,  let  us  not  lose  sight  of  the 
main  phenomena :  millions  of  lymphoid  corpuscles  have 
been  rapidly  produced  somewhere,  and  they  have  been 
produced  from  pre-existing  corpuscles  of  the  same  kind. 
It  will  scarcely  be  suggested,  without  evidence,  that  the 
whole  circulating  blood  has  taken  on  either  an  entirely 
new,  or,  certainly,  an  unwonted  action,  in  order  to  sup- 
ply more  lymphoid  corpuscles  than  ordinary  to  the  par- 
ticular part  where  we  find  them  accumulate ;  and  it  is 
little  less  difficult  to  maintain  that,  because  of  some  local 
injury,  a  multitude  of  lymphatic  or  other  blood-glands  at 
a  distance  have  produced  a  greatly  increased  quantity  of 
corpuscles  to  migrate  into  the  injured  spot.  We  know 
that  the  period  when  the  corpuscles  of  blood-glands  mul- 
tiply rapidly,  and  fall  off  in  large  numbers  into  the  cir- 
culating current,  is  the  period  of  tension  and  turgescence 
of  such  glands — a  tension  and  turgescence  produced  by 
an  extraordinary  afflux  either  of  blood,  or  of  both  blood 
and  chyle.  We  cannot  dissociate,  either  here  or  any- 
where else,  increased  activity  from  increased  supply  of 
nutritive  material,  and  we  have  no  ground  for  supposmg 
that  there  is  an  increased  supply  of  nutritive  material  to 
the  blood-glands  because  of  a  distant  local  injury.  What 
remains  ?  The  admission  is  now  as  full  and  complete 
as  I  could  wish  in  the  instance  of  cartilage,  that  what- 
ever changes  take  place  in  it  are  the  results  of  the  exer- 
cise of  its  own  and  of  no  borrowed  power,  and  though 
some  of  the  old  leaven  clings  to  the  accounts  we  get 
now  and  then  of  the  living  actions  of  bone  and  tooth,  1 
have  no  doubt  that  what  is  true  of  a  living  tissue,  easily 
made  the  subject  of  observation,  is  true  also  of  more 
complex  ones,  with  whose  elements  other  accessory  tis- 
sues are  mingled 

In  the  seats  of  formation  of  pus  we  have  been  con- 
sidering, the  corpuscular  and  formed  tissue  elements  are 
ordinarily  bathed  in  lymph  transuding  through  the  c^ 
ment  spaces  of  the  endothelium  of  their  vessels,  ana 


August  2,  1884.J 


THE  MEDICAL  RECORD. 


117 


having  amongst  it,  here  and  there,  amoeboid  corpuscles  ; 
Dov,  a  greater  amount  of  blood  than  ordinary  circulates 
through  the  vessels,  these  are  dilated,  the  cement  be- 
tveen  their  endothelial  cells  is  of  greater  bulk  and  softer 
than  ordinary ;  the  fluid  plasma  and  lymphoid  corpuscles 
of  the  blood  pass  out  into  the  tissue,  which  becoming 
tease  and  having  its  vitality  impaired,  acts  as  foreign 
natter  to  the  effused  fluid,  and  leads  to  the  disintegra- 
tioD  of  some  of  its  corpuscles  and  coagulation.  Mean- 
time the  supply  of  nutritive  material  increases,  the  red- 
ness, heat,  and  throbbing  become  more  intense,  the 
part  becomes  firm  and  brawny  with  its  increasing  mass 
of  corpuscles ;  and  then,  the  violence  of  the  action 
heing  over,  and  the  vitality  of  the  central  part  of  the 
mass  lessened  by  the  tension,  pallor  and  oedema,  with 
great  relief  from  pain,  succeed  ;  softening,  degeneration, 
and  solution  of  both  tissue  and  exudation  occur,  and  the 
flnid  mass  approaches  the  surface  and  points. 

If  it  seem  strange  that  the  same  process  should  pro- 
dace  necrosis  at  one  part  and  rapid  growth  and  multi- 
plication of  corpuscles  at  another,  let  us  recollect  what 
happens  in  the  healing  of  ulcers.     The  surface  is   no 
longer  supported  by  firm  skin,  therefore  its  vessels  dilate 
and  exudation  occurs  freely.     Stimulated  to  unwonted 
acdvity,  the  connective-tissue  corpuscles  multiply  rapidly ; 
dier  first  form  rounded,  then  spindle-shaped  cells,  and 
iltimately  the  fibres,  corpuscles,  and  ground  substance 
«f  the  new  connective  tissue  of  the  cicatrix,  while  the 
exudation  and  the  migrated  corpuscles  it  contains  dis- 
iotegrate  and  soften  into  pus,  which  escapes  on  the  sur- 
ke.   As  the  healing  proceeds,  the  epithelial  cells  at  the 
c^  of  the  ulcer  divide  and  produce  others  like  them- 
idves,  which  gradually  extend  over  the  surface  and  cover 
ie  newly  formed   connective   tissue   corium   with  an 
^oally  new  epithelial  layer,  both  having  been  derived 
BO  similar  pre-existing  tissue.    The  newly  formed  cica- 
bidal  tissue  scarcely  equals  the  old  in  bulk  ;  therefore 
le  surface  is  genersdly  below  the  surrounding  level,  the 
icer  healing  down,  not  up,  as  Dr.  J.  Hamilton  has  ex- 
Rssedit,  in  his  admirable  demonstration  of  the  changes 
lendant  on  the  healing  of  an  ulcer,  in  the  Journal  of 
wiimy  and  Physiology  for  July,  1879,  from  which  I 
Bt  freely  extracted  these  details. 
Let  us  turn  for  a  moment  -to  the  peritoneal  surface,  on 
Kch  such  a  proliferation  of  cells  as  we  have  been  con- 
iering  has  been  going  on  for  some  time,  and  we  shall 
Ire  no  difficulty  in  understanding  that,  while  effusions 
wi  be  absorbed  by  it  with  great  rapidity  as  long  as  its 
nxnata  are  healthy,  when  these  are  obstructed  or  ob- 
^ed  by  masses  of  proliferating  corpuscles,  the  dia- 
bgm,  pump  as  it  may,  becomes  entirely  powerless  to 
■pty  die  sac  of  its  fluid  contents. 
A  very  interesting  case  occurred  to  Dr.  Whitla,  of 
lb  town,  in  which  obstruction  and  rupture  of  the  tho- 
dc  duct  led  to  the  passage  of  the  whole  chyle  into  the 
idofflinal  cavity  for  several  months.     The  surface  of  the 
tritoneum  was  everywhere' studded  with  tubercles,  and 
consequence  absorption  of  the  fluid  could  not  take 
.    It  was  removed  by  tapping  at  intervals  in  quan- 
of  twenty  pints  or  more. 
The  importance  of  the  physiological  arrangement  by 
^' ii  the  lung  is  irritated  by  lymph  from  the  pleural  to 
vesicular  and  bronchial  surfaces  has,  I  think,  not 
a  sufficiently  appreciated.     The  application  of  cold 
Ac  surface  of  the  body  produces  general  congestion 
the  lung,  taking  the  form  of  pneumonia,  pleuritis,  or 
ndutis,  in  different  persons,  according  to  their  respec- 
Pliabilities  to  these  diseases.     But  the  addition  of  one 
these  diseases  to  another  which  has  been  primarily 
•dnced  is  not  as  easy  to  explain  by  reference  to  their 
^t\j  different  capillary  blood-vessels  as  by  the  great 
Kdom  of  communication  of  their  lymph-passages. 
Jilirary  secretion  discharged  after  stimulation  of  the 
^  da  tympani  of  a  salivary  gland  deprived  of  circulat- 
^biood  is  no  doubt  derived  from  lymph  previously 
•*cd  in  the  gland  itself;  but  under  normal  conditions 


this  exalted  action  of  the  gland  tissue  is  attended  by 
the  circulation  of  a  greatly  increased  quantity  of  blood 
through  it,  a  notable  instance  of  afflux  of  blood  attend- 
ant on  increased  vital  activity  of  a  tissue.  The  case  of 
muscular  tissue  is  exactly  similar.  I  presume  there  can 
be  no  doubt  that  the  increased  activity  of  the  circula- 
tion leads  to  increased  transudation  of  lymph,  which, 
however,  does  not  coagulate,  because  the  healthy  limit 
has  not  been  passed.  But  if  the  lymph  had  transuded 
into  tissue  which  had  been  previously  damaged,  or  dam- 
aged by  the  exudation  itself,  it  would  have  coagulated 
as  the  veritable  exudation  of  inflammation  does. 

When  we  call  to  mind  that  the  cellular  elements  of 
capillary  walls  are  continuous  with  the  framework  of 
lymph  spaces,  which  themselves  communicate  through 
the  endothelial  cement  with  the  lumen  of  the  capillary 
tube,  the  continuity  seems  to  reduce  the  question,  whether 
the  phenomena  of  inflammation  depend  on  increased 
vital  attraction  of  the  tissue  for  blood  or  on  some  altered 
vital  action  of  the  vessels,  to  one  mainly  of  words. 

Yet  the  separation  which  is  effected  by  the  endothelial 
cement  between  the  circulation  of  red  blood-corpuscles 
in  capillary  vessels  and  that  of  lymph  and  white  cor- 
puscles only  in  lymphatic  spaces  is  a  real  separation — a 
separation  by  a  living  colloidal  septum  of  great  liability 
to  change.  It  suggests  the  necessity  of  a  supply  of 
oxygen  and  red  corpuscles  to  some  tissues,  while  others, 
such  as  cornea,  have  all  their  vital  needs  supplied  by 
fluid  plasma  and  white  corpuscles. 

If  I  have  occupied  much  of  your  time  on  matters 
which  I  conceive  to  involve  fundamental  principles  of 
physiology  and  its  twin-sister  pathology,  and  made  free 
use  of  vital  action,. of  which  we  cannot  hope  to  learn 
more  than  the  manifestations,  let  me  plead  the  powerful 
influence  of  early  impressions  gathered  from  a  most 
revered  and  philosophical  teacher,  the  late  Dr.  Alison, 
who  held  that  the  essential  peculiarity  of  inflammation  is 
a  peculiar  perversion  of  nutrition  or  of  secretion. 

In  the  very  pleasant  exammation  of  the  border-ground 
of  physiology  and  pathology,  which  the  writing  of  this  ad 
dress  suggested,  nothing  has  been  more  forcibly  brought 
before  me  than  the  clear  insight  which  the  painstaking 
and  accurate  investigations,  and  the  genius  of  Sir  James 
Paget  gave  him,  long  years  ago,  into  many  vital  phe- 
nomena which  seemed  startling  when  they  were  spoken 
of  individually.  Thus,  in  his  lectures  at  the  College  of 
Surgeons,  from  1847  to  1852,  he  demonstrated  many  of 
the  conditions  under  which  exudations  coagulate,  or  are 
restrained  from  coagulating,  conditions  which  Mr.  Lister's 
subsequent  careful  experiments  have  more  fully  elucidated 
in  connection  with  the  conversion  of  lymph  corpuscle^ 
into  granule  cells,  inflammatory  globules  of  Gluge,  a 
change  first  demonstrated  by  Reinhardt,  and  indepen- 
dently by  Sir  Andrew  Clark.  He  pointed  out  that  it  is 
impaired  nutrition,  fatty  degeneration,  not  death,  which 
leads  to  absorption ;  he  described  most  graphically  the 
hardening  of  the  wall  of  an  abscess  by  coagulation  of 
plasma,  which  neither  the  exuded  corpuscles  nor  the  fluid 
plasma  alone  could  effect,  and  followed  this  by  a  clear  ac- 
count of  the  subsequent  liquefaction  of  the  hardened  mass 
by  what  he  styled  "  liquefaction  degeneration,"  a  great 
feature  in  Dr.  Ziegler's  more  modern  description  and  de- 
monstration of  what  happens  in  the  formation  of  a  blister 
from  a  burn,  and  in  the  disappearance  of  clots  of  blood. 
And  in  the  same  lectures  Sir  James  pointed  out  that 
granulations  and  clots  of  blood  hinder  the  healing  of 
wounds,  leaving  it  for  Dr.  J.  Hamilton,  only  quite  re- 
cently, to  prove  this  by  irresistible  microscopical  evidence. 

Knowledge  derived  from  experience  is  never  more  in- 
teresting than  when  confirmed  by  scientific  examination. 
Dr.  Hamilton's  paper  on  sponge-grafting  recalled  some 
of  the  earliest  lessons  of  my  professional  life  under  a  very 
able  surgeon,  the  late  Mr.  R.  C.  Botham,  of  Chesterfield. 
He  taught  me  to  treat  foul  ulcers  of  the  leg  in  working- 
men  by  scrupulous  cleanliness,  a  pad  of  lint  steeped  in 
solution  of  chloride  of  lime  on  the  ulcer,  then  oiled  silk 


Ii8 


THE  MEDICAL  RECORD. 


[August  2,  1884 


and  a  constantly  applied  bandage,  making  equal  pressure 
from  the  toes  upward,  and  kept  wet  with  solution  of  chlo- 
ride of  lime.  The  success  of  this  treatment  was  most 
marked,  and  I  now  see  that,  beginning  with  an  absolutely 
clean  surface,  the  dressings  acted  antiseptically ;  they 
prevented  the  contact  of  the  atmosphere,  and  afforded 
the  support  which  Dr.  Hamilton  has  shown  to  be  so  es^ 
sential  for  healing  wherever  the  restraining  pressure  dP 
the  skin  has  been  removed. 

■  Dr.  Cor/s  unfortunate  success  in  vaccinating  himself 
with  matter  taken  from  the  cow-pox  pustule  of  a  syphilitic 
child,  will  lead  to  a  reconsideration  of  the  respective 
powers  of  development  of  the  different  constituents  of 
the  blood,  and  to  the  relations  of  its  white  nucleated  to 
its  colored  non-nucleated  constituents. 

At  the  last  meeting  of  the  British  Medical  Association, 
Dr.  Schafer  called  attention  very  pointedly  to  the  func- 
tion of  reproduction  as  belonging  to  the  nucleus  of  a  cell, 
and  it  is  long  since  Dr.  Beale  showed  the  great  power  of 
the  germinal  matter  as  compared  with  that  of  the  formed 
material  of  tissues.  Yet  for  years  the  startling  propo- 
sition has  been  maintained  that  syphilis  is  alone  commu- 
nicable- in  vaccination  by  the  colored  non-nucleated 
formed  constituents  of  the  blood.  Every  medical  man 
knows  the  potency  of  the  lymph  taken  early  from  a  vac- 
cine vesicle  as  compared  with  that  obtained  in  the  later 
stages  when  the  lymph-corpuscles  have  degenerated  into 
pus.  And  the  previous  considerations  which  I  have 
urged  upon  you  show  that  these  lymph-corpuscles  accu- 
mulated in  the  vaccine  vesicle  have  been  produced  in 
this  local  inflammation  either  by  migration  and  subse- 
quent multiplication  of  the  white  corpuscles  of  the  blood 
or  by  active  proliferation  of  the  connective-tissue  cor- 
puscles of  the  part ;  in  either  case  from  germinal  matter, 
active,  living  protoplasm,  if  not  by  the  direct  agency  of 
the  nuclei  of  such  matter. 

Recalling  Mr.  Goodsill's  happy  demonstration,  that  the 
cells  of  lymphatic  glands  are  developments  of  the  epi- 
thelium of  lymphatic  vessels,  and  Dr.  Klein's  beauti- 
ful tracing  of  endothelium  and  the  corpuscles  of  connec- 
tive tissue  at  the  fenestras  of  omenta  and  in  other  situa- 
tions, we  recognize  the  family  relationship  between  the 
lymph-corpuscles  which,  when  detached,  constitute  white 
corpuscles  of  the  blood — the  endothelium  of  serous 
membranes  so  often  found  germmating  abundantly — and 
the  connective-tissue  corpuscles,  which  Dr.  Hamilton 
has  figured  and  described  as  multiplying  with  great  rapid*- 
ity  when  stimulated  by  the  agents  causing  inflammation 
and  unduly  fed  by  a  largely  increased  afflux  of  blood. 

If  it  be  asked  why  syphilis  does  not  more  frequently 
follow  vaccination,  the  reply  is  simple,  that  the  greatest 
care  is  taken  to  select  none  but  perfectly  healthy  chil- 
dren for  the  collection  of  lymph,  and  that  it  is  possible 
that  when  lymph  has  been  collected  where  syphilis, 
though  present,  was  not  recognized,  the  results  may  not 
always  have  been  referred  to  their  proper  causes. 

This  leads  me  to  mention  the  most  difflcult,  exciting, 
and  important  problem  of  the  day :  whether  other  dis 
eases  than  small-pox  can  be  deprived  of  their  virulence 
by  vaccination. 

You  are  aware  with  what  ardor  M.  Pasteur  has  es- 
poused the  affirmative  side  of  this  question,  and  it  was 
very  natural  that,  having  had  a  certain  amount  of  evi- 
dence that  infectious  diseases  of  animals  may  be  de- 
prived of  their  fatal  effects  by  previous  vaccination,  he 
should  have  been  led  to  hope  that  what  is  true  of  one  is 
true  of  all,  and  that  in  this  way  even  hydrophobia  may 
be  deprived  of  its  horrors. 

The  exceedingly  careful  researches  of  Dr.  Klein,  de- 
scribed with  such  accuracy  of  detail  that  they  may  be 
followed  by  any  one,  have  shown  that  there  are  numei- 
ous  pitfalls  in  the  way  of  such  inquiries,  and  that  we  are 
yet  very  far  from  being  able  to  foresee  the  end  of  them. 
Yet  the  progress  made  gives  great  hope  for  the  future, 
for  careful  experiments  by  Drs.  Klein  and  Roy,  and  by 
Dr.   Burdon-Sanderson  and  Mr.   Duguid,  have  clearly 


shown  that  sheep  inoculated  with  anthrax  blood  of  the 
white  mouse,  cattle  inoculated  with  anthrax  blood  of  the 
guinea-pig,  and  cattle  inoculated  with  anthrax  blood  of 
the  South  American  bisachas  are,  for  a  time  at  least, 
insusceptible  of  a  fatal  attack  of  the  malady. 

Dr.  Klein  has  found  that  the  virus  which  communi- 
cates  swine  disease  is  a  form  of  bacillus  which  he  has 
been  able  to  cultivate  out  of  the  body  in  various  ways, 
and  which  is  capable  of  forming  spores  when  exposed  to 
the  air.  But  though  the  organs  of  a  dead  animal  swarm 
with  the  bacilli,  these  soon  degenerate  and  become 
harmless,  without  forming  spores,  if  the  body  be  not  cut, 
and  this  happens  equally  whether  the  body  be  interred 
or  not. 

From  long  experience  I  am  satisfied  that  the  bodies 
of  persons  who  die  of  small-pox,  or  of  puerperal  or 
other  fevers,  may  be  dissected  without  harm  if  properly 
prepared. 

Dr.  Burdon-Sanderson  has  suggested  the  possibility  of 
the  determination  of  the  morbid  process  in  contagious 
diseases  by  an  action  similar  to  the  spontaneous  arrest 
of  septic  fermentations  by  the  development  of  members 
of  the  aromatic  group  of  chemical  compounds  destruc- 
tive of  any  further  manifestation  of  the  vital  activity  of 
septic  microphytes,  and  he  has  undertaken  to  direct  a 
series  of  researches  on  this  subject. 

On  the  one  hand,  what  can  be  more  alarming  than 
that,  under  certain  conditions,  living  organisms  of  the 
utmost  minuteness  enter  the  body  and  multiply  with  a 
rapidity  with  which  fungi  alone  can  multiply,  corrupting 
the  blood,  causing  local  coagulations,  obstructions  of 
vessels,  abscesses,  and  death  ?  and,  on  the  other  hand, 
what  can  be  more  comforting  than  Dr.  Sanderson's  happy 
reference  to  the  manner  in  which  salivary,  gastric,  or 
pancreatic  digestions  furnish  the  means  of  their  own 
arrest,  and  to  the  similar  manner  in  which  the  organisms 
containifig  the  virus  of  contagious  diseases  prepare  the 
means  of  their  own  destruction  ? 

Surely  the  day  will  come  when  it  will  be  seen  that 
gratitude  and  reverence  are  due  to  such  men  as  Pasteur 
and  Koch  and  Sanderson  and  Klein,  rather  than  that 
they  should  be  assailed  with  insult  and  hindered  by  mis- 
chievous legislation,  as  if  they  were  criminals  rather  than 
benefactors  of  the  whole  human  and  animal  races. 

Let  me  mention  certain  t:ircumstances  which  I  think 
indicate  that  we  are  on  the  eve  of  great  simplification 
and  extension  of  our  knowledge.  It  was  a  great  step 
when  the  late  Master  of  the  Mint  taught  us  the  difference 
between  crystalloids  and  colloids,  and  many  of  the  laws 
of  diffusion  and  osmosis.  It  led  the  way  in  an  intelli- 
gent investigation  as  to  how,  in  the  process  of  digestion, 
colloidal  starch  and  albumen  are  fitted  to  pass  through 
the  membranous  walls  of  the  alimentary  canal.  We 
have  found  that  contact  with  a  mere  trace  of  saliva 
or  pancreatic  or  intestinal  secretion  suddenly  converts 
starch  into  sugar,  and  that  a  large  number  of  other  or- 
ganic matters  produce  a  similar  result  Bernard  showed, 
by  experiment,  how  different*  cane,  grape,  hepatic,  and 
diabetic  sugars  are  in  their  relation  to  the  economy;  that 
starch  and  sugar  are  converted  into  fat  by  the  liver ;  and 
that  by  an  insignificant  lesion  of  the  medulla  oblongata 
temporary  diabetes  can  be  produced.  And  we  know, 
further,  that  during  the  conversion  of  starch  into  sugar 
there  are  many  almost  insensible  stages.  The  process 
is  influenced  by  numerous  conditions  which  require  in- 
vestigation at  every  step  to  enable  us  to  trace  these  sub- 
stances at  their  entrance  into  the  economy,  in  the  re- 
gions where  they  contribute  to  the  production  of  heat 
and  motion,  and  until  their  final  deposition  or  discharge 
in  some  more  oxidated  form. 

Similarly  I  would  suggest  the  most  careful  observation 
— not  by  one  person,  but  by  every  one  in  his  own  sphere 
— of  the  conditions  under  which  albuminoid  matters  are 
changed,  whether  after  their  entrance  into  the  upper  or 
lower  end  of  the  alimentary  canal ;  of  those  under  which 
they  pass  into  the  blood,  circulate,  and  become  tissue ; 


August  2,  1884.] 


THE   MEDICAL  RECORD. 


119 


also  of  the  forms  under  which  they  reappear  in  their 
variouslj  oxidated  conditions  in  the  urinary  excretion  in 
health  and  disease. 

The  marvellous  differences  between  albumen  of  the 
egg  and  serum  and  albumen  washed  free  from  salts,  or 
when  changed  into  acid  or  alkali  albumen  ;  the  modes 
of  production  of  peptone  and  its  varieties ;  the  diflfer- 
ences  in  the  conditions  and  results  of  the  action  of  the 
gastric,  pancreatic,  and  intestinal  secretions ;  and  very 
specially  the  appearance  in  the  urine,  in  disordered  or 
diseased  conditions,  of  albuminoid  substances  yielding 
reactions,  showing  that  the  variety  of  forms  in  which 
these  substances  appear  are  no  less  numerous  or  closely 
related  than  those  of  the  varieties  of  sugar  and  starch, 
all  point  to  the  necessity  of  rigorous  investigation,  and 
to  the  possibility  of  presenting  these  substances  and 
their  various  alternations  in  a  light  far  more  simple  than 
has  as  yet  been  suspected. 

It  is  unfortunately  the  custom  in  this  country-  to  leave 
such  investigations  to  be  undertaken  by  private  individu- 
als, very  few  of  whom  have  the  necessary  physiological 
and  chemical  knowledge,  and  fewer  still  have  the  requi- 
site time  and  means  at  their  disposal.  That  we  have 
men  admirably  fitted  to  direct  and  aid  or  to  conduct 
sQch  inquiries  is  plain  from  the  researches  of  Simpson 
and  Thudichum  and  the  aid  rendered  by  Gamgee, 
Ralfe,  and  T.  C.  Charles.  And  I  am  not  without  hope 
that  the  public  spirit  of  this  great  country  may  yet  be 
aroused  by  the  expressed  opinion  of  the  President  of 
the  Royal  Society  and  others  as  to  the  duties  of  the 
state  in  such  matters,  and  that  something  worthy  of  the 
nation  may  yet  be  done  to  aid  the  teaching  of  science 
and  to  promote  scientific  inquiry. 


PRACTICAL  OBSERVATIONS  ON  THE  HUMAN 
EAR  AND  ITS  DISEASES,  WITH  ILLUSTRA- 
TIVE CASES. 

By  SAMUEL  SEXTON,  M.D., 

AUBAL  S17RCBON   TO  THB   NBW  YOKK   BYB  AND  BAR   INF1RMAKY. 

I. — ^The  External  Ear. 

(Continued  firom  No.  713,  p.  7.) 
HiGMATOMA    AURIS — SYMPTOMS. 

The  affection  may  begin  in  either  ear,  but  most  frequently 
attacks  the  left ;  both  ears  are  sometimes  attacked  about 
the  same  time,  the  left,  however,  being  usually,  it  is  al- 
lied, the  first  to  exhibit  symptoms  of  invasion.  The 
exadation  always  takes  place,  as  far  as  my  own  experience 
goes,  on  the  outer  surface  of  the  pinna,  and  seldom 
affects  the  inner  surface  at  any  period  of  the  disease. 
The  swelling  in  most  cases  begins  near  the  superior 
border  of  the  pinna,  but  it  may  show  itself  on  any  por- 
tion of  the  exterior  surface,  including  the  concha.  The 
bbule  is  never  directly  affected,  since  it  contains  no 
anilage,  and  the  cartilaginous  portion  of  the  external 
loditoiy  canal  is  seldom  involved.  The  tragus  seems  to 
(iijoy  entire  immunity  from  attacks. 

This  selection  of  the  outer  surface  of  the  auricle  seems 
to  be  owing  to  the  greater  vascularity  of  this  region,  upon 
liuch  the  branches  of  the  anterior  and  posterior  auricu- 
lar arteries  ramify  and  anastomose,  and  to  the  fact  that 
^  almost  invariably  receives  the  impact,  when  the  auricle 
tf  struck,  with  greatest  force.  Where  there  is  an  inflam- 
Biitory  movement  in  the  parts,  the  connective  tissue  on 
tk  inner  suriiace  of  the  pinna  may  become  the  seat  of 
suppurative  action  and  an  abscess  may  form  ;  or,  should 
perforation  of  the  cartilage  take  place,  the  contents  of 
ti»«  tumor  may  pass  through  from  the  anterior  cyst,  sepa- 
titing  the  perichondrium  from  the  cartilage  on  the  inner 
wface,  and  escape  into  the  connective  tissue  even. 

^Tieo  the  invasion  takes  place  the  affected  region 
ssoall?  presents  a  hyperjeraic  appearance ;  frequently 
^^  is  in  lunatics  a  very  decided  flow  of  blood  toward 


the  head,  producing  great  capillary  turgescence  of  the 
face,  ears,  and  eyes ;  in  some  instances  an  effusion  of 
blood  beneath  the  conjunctiva  of  the  eye  has  been 
known  to  occur  simultaneously  with  the  appearance  of 
the  othaematoma.  In  the  more  severe  cases,  where  the 
characteristic  effusion  takes  place  rapidly  with  inflamma- 
tory action,  there  is  often  an  elevation  of  temperature ; 
and  in  nearly  all  instances  the  integument  assumes  a 
bluish  or  purplish  hue.  The  affected  organ  is  seldom 
very  painful,  even  where  the  tumor  is  greatly  distended 
or  roughly  handled,  especially  in  boxers  and  lunatics, 
where  the  parts  have  been  subject  to  rough  treatment 
from  repeated  contusions ;  in  the  latter,  however,  the 
ears  are  wanting  in  sensibility  at  all  times.  The  writer 
has,  however,  frequently  observed  that  sensibility  is  very 
much  exalted  in  some  cases  occurring  in  sane  persons. 

The  progress  of  the  tumor  varies  very  much  ;  it  may  rise 
to  a  considerable  size  in  the  course  of  a  few  hours,  and 
when  first  seen  may  be  as  large  as  an  almond  or  a  walnut. 
Sometimes  the  distention  continues  to  progress  rapidly, 
the  walls  becoming  thinner  in  consequence  of  the  stretch- 
ing, until,  finally,  in  the  worst  cases,  they  undergo  spon- 
taneous rupture  unless  relieved  by  an  operation.  In 
asylum  cases  it  is  not  unusual  to  allow  the  cyst  to  burst 
in  this  manner ;  thus  of  the  twenty-four  cases  reported 
by  Hun  fifteen  niptured  spontaneously ;  in  one  of  them 
the  lefl  ear  burst  on  the  twelfth  day  at  the  upper  part 
of  the  concha,  while  the  patient  was  sitting  in  a  chair,  and 
the  contents  **  were  thrown  to  the  ceiling,  a  distance  of 
twelve  feet,  so  as  to  stain  the  plaster." 

These  tumors  are,  however,  frequently  without  some 
of  the  symptoms  of  inflammatory  action,  passing  through 
all  of  the  stages  of  the  disease  without  either  heat  or 
pain  being  experienced  by  the  patient.  This  variety 
manifests  a  disposition  to  develop  slowly,  and  has  a 
tendency  to  spread  itself  laterally  rather  than  in  thick- 
ness.    The  following  case  is  one  of  this  description  : 

Case  I. — W.  W ,  an  Englishman,  forty-three  years 

of  age,  by  occupation  a  negro  minstrel ;  health  good,  and 
he  claims  to  have  no  bad  habits ;  never  had  any  aural  dis- 
ease before ;  came  to  the  New  York  Eye  and  Ear  In- 


FlG.  T. 

firmary  May  4,  1880.  States  that  two  weeks  ago, 
while  washing  the  burnt  cork  from  his  face,  he  felt  a 
slight  soreness  on  the  top  of  the  right  auricle.  On  ex- 
amination he  found  a  small  tumor  on  the  outer  aspect 
of  the  auricle,  which  afterward  gradually  increased  in 
size  until  it  was  larger  in  diameter  than  a  twenty-five 
cent  piece ;  it  then  obliterated  the  antihelix,  and  finally 
became  about  one-half  an  inch  in  thickness.     On  shak- 


I20 


THE   MEDICAL  RECORD. 


[August  2,  1884. 


ing  his  head  the  patient  could  ''  feel  the  contents  of  the 
tumor  rattle." 

Dr.  Henry  D.  Joy,  to  whose  kindness  I  am  indebted 
for  the  case,  had  painted  the  tumor  with  the  tincture  of 
iodine  for  the  first  few  days,  and  it  had  decreased  some- 
what in  size.  When  the  iodine  stains  disappeared  the 
color  of  the  tumor  was  found  to  be  but  little  more  red 
than  normal,  but  its  walls  were  thickened.  Under  the 
expectant  plan  the  fluid  continued  to  be  reabsorbed 
quite  rapidly,  and  later  on  the  contents  had  a  doughy  feel. 

June  4th. — The  patient  himself  has  occasionally  painted 
the  ear  with  tincture  of  iodine,  and  for  the  past  two 
weeks  it  has  diminished  notably  in  size.  Thickening 
and  immobility  of  the  integument,*  however,  remain. 
There  is  no  shrivelling  of  the  cartilage,  and  but  little 
deformity  from  the  remaining  induration  of  the  parts.  It 
is  the  belief  of  the  patient  that  the  auricle,  previous  to 
the  beginning  of  the  swelling,  had  been  struck  a  slight 
blow  by  a  papier-mach6  stove,  which  he  had  to  throw 
upon  his  shoulder  during  a  play. 

Fig.  I  represents  the  appearance  of  the  ear  imme- 
diately after  the  tumor  had  commenced  to  subside. 

In  some  instances,  however,  cases  like  the  above,  after 
remaining,  ifi  statu  quo  for  a  variable  period  of  time, 
suffer  an  exasperation  from  repeated  contusions,  and  an 
othaematoma  of  very  considerable  size  may  be  developed. 
Such  an  aggravation  may  also  be  brought  about  by  in- 
judicious operative  procedures,  or  probably  by  an  ex- 
acerbation of  cerebral  symptoms,  giving  rise  to  increased 
activity  of  the  general  circulation  about  the  head  and 
ears. 

In  the  beginning  of  an  attack,  and  during  its  progress, 
the  patient  sometimes  experiences  a  feeling  of  heat  in 
the  affected  organ,  like  the  extreme  congestion  due  to 
flushing ;  in  the  insane,  however,  precursory  signs  are 
not  likely  to  be  reported. 

Generally  the  outlines  of  the  outer  surface  of  the 
pinna,  formed  by  the  foldings  of  the  cartilage,  are  more 
or  less  obliterated,  according  to  the  extent  of  the  tumor; 
where  there  were  ridges  and  depressions  before,  the  sur- 
face will  be  smooth — usually  convex  even. 

The  contents  of  the  tumor ^  in  the  beginning,  may  con- 
sist of  blood  and  serum,  or  of  the  latter  principally ; 
even  when  at  first  serous,  the  fluid  usually  becomes  sero- 
sanguinolent  sooner  or  later.  In  some  instances,  how- 
ever, the  serous  character  continues  throughout.  In 
most  cases  an  early  formation  of  coagula  takes  place  in 
the  tumor,  which,  not  being  reabsorbed,  increases  en- 
suing deformity.  In  the  milder  form  of  the  affection, 
sometimes  described  as  **  cedematous,"  but  little  fibrous 
tissue  remains,  reabsorption  being  more  complete  ;  such 
cases  seem  to  pass  through  all  of  the  stages  with  but 
moderate  inflammatory  action. 

The  wound  which  affords  an  outlet  for  the  contents 
of  these  cysts,  when  they  require  any,  whether  from  punc- 
ture or  due  to  spontaneous  rupture,  has  no  tendency  to 
remain  open,  and  the  cavity,  therefore,  sometimes  re- 
fills in  the  course  of  a  few  hours  ;  on  the  other  hand,  in 
certain  cases  the  cyst  pours  out  fluid  so  rapidly  that  a 
discharge  constantly  trickles  down  from  the  opening,  thus 
preventing  the  wound  from  closing. 

The  duration  of  othczmatoma  will  of  course  vary  greatly, 
depending  as  it  does  on  the  severity  of  the  case,  the  ra- 
pidity of  reabsorption,  and  the  habits  of  the  patient  ; 
thus  in  lunatics,  inebriates,  and  boxers  the  organ  is  liable 
to  repeated  contusions,  giving  rise  to  aggravations  which 
may  retard  the  cure.  Sometimes  reabsorption  comes  to 
a  stand-still,  and  a  considerable  tumor  remains  for  an 
indefinite  period  of  time. 

The  writer  has  seen  a  case  of  this  kind  which  is  given 
below : 

Case   II.  —  Charlotte  K ,  aged   thirty-nine,  was 

admitted  to  the  New  York  City  Lunatic  Asylum  in  May, 
1880,  when  suffering  from  her  first  attack  of  acute  melan- 
cholia. She  had  delusions  of  persecution  and  suicidal  ten- 
dencies, was  subject  to  exacerbations  of  excitement,  dur- 


ing which  she  was  violent  and  destructive  until  quieted  by 
large  doses  of  sedatives.  In  June,  1883,  haematoraa 
commenced  in  the  left  ear,  which  ran  its  course  in  two 
months  without  any  particular  treatment,  leaving  much 
deformity.  On  September  12,  1883,  othaematoma  com- 
menced in  the  right  ear  :  at  first  it  was  intensely  red,  but 
finally  became  purplish  in  appearance.  No  treatment 
October  31st. — The  patient  was  examined  by  the  writer 
and  a  considerable  collection  oC  fluctuating  fluid  was  de- 
tected in  a  cyst,  over  an  inch  in  length,  on  the  outer  sur- 
face of  the  right  auricle.  It  was  recommended  that  the 
fluid  be  evacuated  by  a  rather  free  incision,  the  walls  of 
the  cyst  painted  with  Churchill's  solution  of  iodine,  and 
the  auricle  bandaged  to  the  head  so  as  to  cause  a  moder- 
ate amount  of  pressure.  This  was  done  by  Dr.  L.  C. 
Toney,  though  through  some  misunderstanding  three 
successive  applications  of  the  iodine  were  made.  By 
November  3d  the  walls  were  adherent,  and  on  Novem- 
ber 9th  the  wound  was  found  healing  by  granulation. 
When  the  writer  last  saw  the  ear,  on  November  23d, 
it  was  found  that  the  sac  was  entirely  obliterated.  The 
cicatrix  was  slightly  stained  from  the  excessive  use  made 
of  the  iodine  solution.  There  was  scarcely  any  deformity. 
In  some  instances  a  sinus  remains,  aflbrding  a  serous 
discharge  which  may  continue  for  an  indefinite  period 
The  following  is  a  case  of  this  kind  : 

Case  III. —  Annie  M ,  aged  thirty-five,  was  ad- 
mitted to  the  New  York  City  Lunatic  Asylum,  March, 
1879,  with  acute  mania.  Soon  afterward,  on  refusing 
food,  was  forcibly  fed — the  process  consisting  in  placing 
the  head  of  the  patient  under  the  left  arm  of  the  operator, 
while  with  his  left  hand  a  wedge  is  held  in  the  patient's 
mouth,  and  with  the  right  hand  the  feeding-tube  is  in- 
serted. Subsequently  haematoma  developed  in  the  left 
ear.  Although  it  seems  probable  that  the  ear  was  bruised 
during  the  forcible  feeding,  yet  the  patient  was  frequently 
engaged  in  fights  with  other  patients  at  this  time,  when 
she  was  liable  to  receive  blows  upon  the  ear.  There 
was  no  treatment,  and  the  tumor  passed  into  a  chronic 
stage,  which  escaped  observation  until  September,  1883, 
when  serum  was  observed  to  ooze  from  an  opening  in 
the  outer  surface  of  the  auricle  just  above  the  condia. 
This  opening  was  enlarged  and  the  cavity  syringed  out 
with  a  solution  of  carbolic  acid  with  no  result.  On 
^  October  19th  the  writer  examined  the  case  and 
"j  determined  to  obliterate  the  sac  by  an  operation. 
The  sac  was  laid  freely  open,  cleansed  of  the  co- 
pious flow  of  blood  and  other  contents,  and  the 
walls  were  then  thoroughly  painted  with  Church- 
ill's solution  of  iodine.  Notwithstanding  the  em- 
ployment of  such  pressure  as  was  found  to  be 
practicable,  the  parts  healed  up  again,  leaving  a 
small  sinus  as  before.  Subsequently  the  opera- 
tion was  tried  three  different  times  by  Dr.  Dent, 
the  assistant  superintendent,  without  avail. 

November  23d. — ^The  writer  finding  a  slight 
sero-sanguinolent  discharge  remaining,  concluded 
to  try  to  obliterate  the  tumor  by  scraping  its  walls 
with  a  cutting-scraper.  It  was  found,  however, 
1  that  the  walls  of  the  sac,  which  proved  to  be  very 
large,  consisted  of  broken-up  and  shrivelled  car- 
tilage, presenting  rough  and  uneven  surfaces.  A 
partly  detached  plate  of  cartilage  was  found  lying 
on  the  outer  wall,  and  the  edge  of  the  superior 
portion  of  the  heUx  could  be  felt.  There  was  a 
deficiency  in  the  cartilage  composing  the  inner 

I  wall  of  the  sac.  It  was  evident  that  the  irregu- 
larities of  the  walls  had  prevented  adhesion  of 
the  surfaces  from  taking  place. 
Operation, — With  scraper  (Fig.  2)  every  portion 
of  the  secreting  surface  was  destroyed,  considera- 
FiG.  a.  5ie  broken-down  tissue  being  brought  away  by  the 
instrument,  which  had  to  be  cleaned  several  times.  The 
oozing  of  blood  was  quite  profuse  for  a  time.  The  parts 
were  thoroughly  cleansed  with  hot  water,  and  pressure  es- 
tablished by  bandaging  the  padded  ear  firmly  to  the  side 


\ 


August  2,  1 884,] 


THE   MEDICAL  RECORD. 


121 


of  the  bead.  It  was  noted  that  throughout  the  operation 
the  patient  seemed  to  experience  no  pain  whatever.  No 
aoxstfaetic  was  employed.  The  parts  healed  kindly,  pres- 
sure was  maintained  for  some  time  afterward.  After  the 
first  week  there  seemed  to  be  some  improvement,  but 
when  1  saw  the  patient,  on  December  2 2d,  the  cure  was 
incomplete.  It  is  very  evident  that  union  can  only  be 
obtained  between  the  walls  of  the  sac  in  this  case  by 
dissecting  out  the  irregular  and  detached  masses  of  carti- 
lage whidi  prevent  them  coming  together. 

in  a  very  considerable  number  of  cases  the  disease 
will  terminate  spontaneously  in  from  four  to  eight  weeks, 
depending  somewhat  on  the  extent  of  perichondrium 
afected  and  the  quantity  of  the  effusion ;  othaeniatoma, 
however,  cannot  be  ^aid  to  have  any  regular  course 
vhere  it  occurs  in  irresponsible  or  uncontrollable  pa- 
tients. 

Subjective  symptoms, — ^These  usually  are  present  where 
occlusion  of  the  external  auditory  meatus  is  produced  by 
swelling  of  the  concha ;  they  consist  in  deafness — due  to 
dosureof  the  canal — and  tinnitus  aurium — from  increased 
tension  of  the  membrana  tympani.  The  extent  of  these 
symptoms  in  lunatics  cannot  with  accuracy  be  determined. 
CompluaHons. — The  retroactive  consequences  of  this 
local  trouble  in  the  insane  need  not  be  considered  here, 
yet  it  is  worthy  of  note  that  the  posterior  auricular  artery, 
tbroogfa  one  of  its  branches — the  stylo-mastoid — com- 
municates with  the  middle  meningeal  by  anastomosis, 
thus  establishing  a  significant  and  important  relationship 
between  the  ear  and  the  meninges  of  the  brain.  In  the 
mentally  sane  this  becomes  a  factor  of  serious  import,  and 
sboold  not  be  overlooked  \  besides,  more  or  less  general 
nervous  sympathy  may  exist  in  sane  patients. 

Parts  contiguous  to  the  ear  are  sometimes  implicated 
in  an  extension  of  the  inflammatory  process  ;  neuralgia 
maj  be  kindled  into  action,  and  general  febrile  action 
flttj  supervene.  Whilst  othaematoma  may  be  produced 
b]r  disease  or  wounding  of  the  cartilage  of  the  external 
auditoiy  canal,  it  seldom  extends  itself  to  these  parts 
from  the  pinna  ;  and  the  middle  ear,  so  far  as  is  known  to 
the  writer  at  least,  has  never  been  invaded  by  an  exten- 
sve  inroad  of  the  inflammatory  process. 

DIAGNOSIS   OF  OTHiGMATOMA. 

The  "  Asyluna  Ear"  was,  by  all  observers  half  a  cen- 
huy  ago,  regarded  as  a  curiosity  simply,  and  even  at  the 
present  time  it  seems  to  very  often  escape  attention 
entirely,  or  to  be  merely  entered  in  asylum  case-books 
IS  a  nondescript  phenomenon.  It  is  to  be  hoped  that  a 
nnt  of  knowledge  in  this  respect  will  not  long  prevail 
ibcrc  the  disease  is  liable  to  occur,  and  where  treatment 
may  do  much  to  ameliorate  the  condition  of  the  patient. 
In  fact,  the  want  of  adequate  knowledge  in  regard  to 
othematoma  seems  scarcely  any  longer  excusable  when 
we  consider  the  light  that  has  been  thrown  upon  the 
sobject  during  the  past  twenty  years  by  various  authors. 

In  distinguishing  this  afiection  from  erysipelas,  phleg- 
Dionous  inflammation,  frost-bite,  burns,  eczema,  tuber- 
oikr  syphilis,  and  other  cutaneous  affections  one  almost 
consUnt  causative  agency  should  be  first  sought  for, 
aamdjr,  trauma.  Whether  predisposing  conditions  are 
[CMent  or  not,  the  history  will  give  unmistakable  evi- 
dences oi  this  factor.  There  may  often  be  reasons  for 
Bipyressing  the  truth;  persons  may  desire  to  conceal 
it  £iets  of  blows  having  been  administered,  or  they  may 
i»rc  been  so  slight  as  to  have  escaped  attention,  never- 
fcless  where  othaematoma  is  suspected,  inquiries  in  this 
fcction  should  be  diligently  pressed. 

The  essential  nature  of  the  afiection  depending  on  a 
pexkhondritis  of  the  cartilage  of  the  auricle,  its  exist- 
cQce  may  be  readily  detected  by  examining  the  con- 
sents of  the  tumor,  which  will  be  found  to  be  serous  or 
iMD^sanguinolent  These  tumors  are  usually  of  rapid 
fonriation,  and  speedily  refill  again  on  being  evacuated. 
I*  *iU  be  found  that  they  have  well-defined  and  resisting 
'^j  a  fact  which  may  be  determined  by  exploring  the 


walls  of  the  tumor  with  a  probe  after  it  has  been  incised 
or  ruptured. 

Abscesses  or  blood  extravasations  rarely  develop  in 
the  scanty  connective  tissue  of  the  auricle,  and  they  are 
much  more  limited  in  dimensions  than  othaematoma ; 
their  walls,  moreover,  give  way  to  moderate  distention, 
and  their  progress  will  be  found  to  be  less  protracted  than 
the  tumors  under  consideration.  The  serous  or  sero- 
sanfi;uinolent  discharge  which  characterizes  othaematoma, 
could  not  have  its  origin  in  a  cavity  formed  by  the  break- 
ing down  of  the  connective  tissue  by  effused  blood,  but 
must  arise  from  a  secreting  surface. 

Suppurative  perichondritis  has  been  alluded  to  by 
writers,  but  it  is  difiicult  to  see  how  pus  could  be  se- 
creted by  these  cysts ;  extravasated  blood  may,  however, 
become  putrescent,  or  a  perforation  of  the  walls  of  the 
cyst  may  afibrd  a  communication  with  an  abscess  behind 
the  cartilage  of  the  auricle,  or  with  the  deeper  parts 
about  its  attachment  to  the  temporal  bone. 

Abscesses,  however,  may  develop  in  the  post-auricular 
connective  tissue  during  the  progress  of  cases  of  marked 
inflammator>'  tendency  or  as  a  result  of  contusions.  In 
such  cases,  or  where  swelling  occurs  without  niahj 
an  asymmetrical  prominence  of  the  auricle         ^ 


Fig.  3. 

The  following  case  is  in  point.  Fig.  3  is  an  excellent 
likeness  of  the  patient,  and  Fig.  4  is  a  view  of  the  post- 
aural  abscess,  natural  size. 

Case  IV. — Michael  Y ,  thirty-five  years  of  age  ; 

married  ;  intemperate ;  entered  New  York  City  Asylum 
for  the  Insane,  with  dementia,  1872.  Is  morose  and 
stupid.  In  1878  found  to  imagine  that  he  had  a  woman 
in  him.  In  1882,  delusions  of  dead  bodies  in  his  head. 
April,  1883,  extravagant  delusions,  as  head  filled  with 
articles  of  food.  The  eyebrows  have  almost  disappeared 
from  constant  rubbing,  tries  to  rub  his  eyes  out.  No- 
vember 24, 1883,  haematomaof  the  right  pinna  observed. 
Continually  rubs  side  of  head  with  stones  and  beats  him- 
self. November  25th,  the  tumor  on  inner  surface  of 
auricle  was  incised.     .     .     . 

I  saw  this  patient  on  November  27  th,  and  the  follow- 
ing is  an  abstract  of  the  notes  taken  by  Dr.  Robert  Bar- 
clay, who  assisted  me  :  The  right  auricle  is  thickened, 
the  outlines  of  the  outer  surface  being  almost  obliterated. 
The  whole  organ  is  red  and  tender,  although  sensibility  is 
much  lowered.  A  large  fluctuating  abscess  occupies  the 
lower  half  of  the  inner  surface  of  the  pinna,  and  extends 
downward,  spreading  out  over  the  mastoid  process  and 
involving  the  lobule.  There  is  a  slight  indentation  where 
incision  was  made  on  the  25  th,     It  has  been  treated  by 


122 


THE   MEDICAL   RECORD. 


[August  2,  1884. 


applications  of  iced  water.  The  writer  made  an  inci- 
sion, about  half  an  inch  long,  into  the  lower  part  of  the 
abscess,  evacuating  about  a  fluid  ounce  of  pus.  The 
teeth  of  this  patient  were  very  carious,  quite  so  on  the 
right j  side,]|  and  were  all  of  them  enveloped  in  much 


Fig.  4' 

tartar.  It  would  seem  that  the  post-aural  abscess,  al- 
though consecutive  to  the  othaematoma,  was  due  to  the 
constant  bruising  of  the  parts  by  the  patient  himselC 
The  othaeroatomatous  tumor  on  the  exterior  surface  of 
the  auricle  probably  gave  rise  to  unusual  vascularity  in  the 
whole  organ,  and  there  may  have  been  an  opening  in  the 
cartilage  permitting  the  passage  of  the  contents  of  the  cyst 
into  the  connective  tissue  behind  the  ear,  but  there  was 
no  evidence  of  any  separation  of  the  perichondrium  from 
the  cartilage  on  its  inner  surface,  and  the  contents  of  the 
abscess  apparently  contained  no  serum.  There  was  no 
history  as  to  the  exact  duration  of  the  othaematoma. 

In  many  cases  of  othaematoma  the  auricle  does 
not  stand  off  from  the  head,  the  disease  bein^  limited 
to  the  wing  of  the  ear  throughout.  Parts  contiguous  to 
the  auricle  are  always  the  last  to  be  affected,  if  invaded 
at  all.  The  trouble  may  be  distinguished  from  erysipelas, 
for  which  it  was  formerly  sometimes  taken,  by  its  well- 
defined  sacculated  appearance  and  the  absence  of  super-^ 
ficial  changes  common  in  erysipelas.  Eczema  and  ery- 
sipelas, unlike  othaematoma,  are  liable  to  extend  into  the 
external  auditory  canal,  while  the  latter,  at  most,  usually, 
occludes  the  meatus  by  the  encroachment  of  its  sac 
The  cutaneous  affections  mentioned  above,  moreover, 
frequently  invade  the  neighboring  parts,  especially  the 
inner  surface  of  the  auricle  ;  none  of  them,  however, 
leave  the  deformity  which  characterizes  othaematoma. 
Naevi  may  resemble  othaematoma  very  closely  in  some 
instances.  Dr.  Gorham  Bacon  showed  the  writer  a  case 
of  this  kind  occurring  in  a  woman  where  a  large  portion 
of  the  auricle  was  involved.  The  marked  pulsation  and 
absence  of  fluctuation  in  such  a  case  would  serve  to 
distinguish  it  from  othaematoma.  The  age  of  the  patient 
should  be  considered  in  arriving  at  a  diagnosis ;  thus 
eczema  is  most  frequent  in  infancy  and  childhood,  whilst 
othaematoma  is  more  particularly  a  disease  of  adult  life. 
Cases  of  othaematoma,  it  is  true,  have  been  reported  as 
occurring  in  children  ;  one  of  them,  it  is  stated,  occurred 
*'idiopathically"  in  a  child  one  year  and  three  months 
old,  where  an  otorrhoea  and  eczema  of  the  external 
auditory  canal  preceded  the  attack.*  The  writer  has 
never  seen  a  case  of  this  kind,  and  is  convinced  that 
their  occurrence  is  extremely  infrequent. 

(To  be  continued.) 

>  Dr.  Weil,  Stuttean :  Beiixag  aur  Casuistik  der  Otfaamatome— Moaataduift  ftr 
Ohrenhdlkuade,  May,  1883. 


ON   RESPIRATORY   MEDICAMENTS. 
By  Professor  GERMAIN  S^E, 

MEMBER  OF  THE  ACADEMY  OF  MBDIONE,    AND    OP    THE    FACL'LTV  OP   MlDICIllBf 
PAKIS,   FRANCE. 

Pneumotherapy  constitutes  an  artificial  respiratory 
method,  calculated  to  facilitate  respiration  as  well  as  the 
central  and  peripheral  circulation.  It  comprises  the 
fixed  respiratory  apparatuses,  known  for  many  years,  but 
whose  effects  on  the  heart  and  circulatbn  have  less  en- 
gaged the  attention  of  observers  than  the  action  of  these 
artificial  atmospheres  on  respiration  and  nutrition. 

Pneumotherapy,  in  its  more  modem  development,  is 
practised  by  the  aid  of  portable  apparatuses,  invented  by 
Waldenburg,  with  more  precise  aifd  special  applications 
to  diseases  of  the  heart  and  blood-vessels. 

EFFECTS    OF   NORMAL   INSPIRATION   AND    EXPIRATION    ON 
THE   THORACIC   ORGANS. 

Respiration  in  free  air  exercises  a  marked  influence  on 
the  circulation. 

Inspiration, — The  pulmonary  air  is  in  a  state  of  diffu- 
sion, and  thereby  exercises  an  aspiration  or  suction  on 
the  vascular  system  in  such  a  manner  that  during  inspira- 
tion the  venous  blood  arrives  with  greater  facility  and 
speed  from  the  head  and  trunk  to  the  thorax  and  heart ; 
the  latter  dilates  easily  to  the  inflowing  current  During 
this  period,  nevertheless,  the  expulsion  of  blood  fix)m  the 
heart  takes  place  with  less  energy,  and  for  this  reason 
vascular  tension  diminishes  during  the  inspiratory  act 

It  is  only  at  the  end  of  inspiration  that  the  pressure  of 
the  pulmonary  air  becomes  equal  to  that  of  the  atmo- 
sphere, and  then  the  modifications  in  the  circulation, 
dfected  by  inspiration,  end. 

Expiration.— Here  ever3rthin^  is  reversed ;  the  tho- 
racic parietes  sink  in,  compressing  the  air  in  the  lungs 
which  undergoes  condensation  ;  there  results  at  the  same 
time  a  pressure  on  the  heart  and  great  vessels.  The 
venous  blood  flows  with  diflSculty  into  the  thoracic  cavity 
and  heart,  the  veins  of  the  body  swell ;  the  contractions  of 
the  heart  take  place  with  more  energy^  but  without  power 
to  force  a  great  deal  of  blood  into  the  arterial  tubes. 

EFFECTS   OF   INSPIRATION   OF  COMPRESSED  AIR. 

Mechanical  effects  on  the  lungs, — ^The  inspiration  of 
compressed  air  determines  at  first  a  sensation  of  plen- 
itude and  distention  in  the  thorax,  resulting  fi-om  the  ex- 
pansion of  the  lungs  and  the  entire  thoracic  cavity,  an 
expansion  which  is  more  marked  than  that  which  follows 
the  most  powerful  voluntary  inspiration,  although  the  in- 
spiratory muscles  do  not  in  this  case  put  forth  any  sensible 
effort.  The  compressed  air  which  penetrates  the  lungs 
begins  by  diffusing  itself  with  the  residual  air  in  the 
lungs,  and  it  is  not  till  the  end  of  inspiration  that  it 
reaches  the  degree  of  pressure  which  it  had  in  the  appa- 
ratus. The  quantity  of  air  introduced  into  the  lungs  and 
then  eliminated  during  these  inspirations  of  compressed 
air  amounts  to  one  thousand  cubic  centimetres,  according 
to  Waldenburg,  and  according  to  Speck,  to  seven,  eight, 
and  even  ten  thousand  cubic  centimetres  each  minute ;  this 
explains  the  thoracic  enlargement,  which  may  exceed  the 
normal  by  four  centimetres.  The  lungs  become  thor- 
oughly permeated  with  air,  and  clear  themselves  of  bron- 
chial mucus.  Still  later,  both  inspiratory  and  expiratoiy 
force  is  increased,  and  this,  not  only  during  the  pneu- 
matic treatment,  but  for  some  time  after. 

The  same  may  be  said  of  that  increase  of  vital  capacity 
which  results  from  treatment  by  compressed  air,  it  lasts 
for  a  considerable  time.  The  condition  of  success  is  not 
to  exceed  -^  of  the  atmosphere  pressure,  for  if  this  con- 
dition be  not  observed  serious  accidents  may  occur,  such 
as  loss  of  elasticity  of  the  pulmonary  tissue,  pulmonary 
emphysema,  and  hemorrhages  from  rupture  of  blood-ves- 
sels, if  the  lung-tissue  be  at  all  altered. 

Effects  of  inspiration  of  compressed  air  on  the  heart 
and  circulation. — [The  entire  subject  of  the  ph3rsiological 


August  2, 1884.] 


THE  MEDICAL   RECORD. 


123 


^ts  of  inspiration  of  compressed  air  demands  revision 
and  restatement  No  one  has  acknowledged  this  more 
plainlj  than  Professor  S6e  himself,  when,  after  a  long 
and  interesting  statement  of  Waldenberg's  theory,  he 
confesses  that  it  has  been  overthrown  by  recent  sphygmo- 
graphic  explorations.  This  being  the  case,  I  have  taken 
die  liberty  to  omit  this  portion  oiProfessor  S6e's  lecture, 
for  however  reasonable  any  theory  may  be,  if  it  will  not 
stand  the  test  of  facts  it  is  worth  nothing. 

Waldenberg  established  the  following  laws :  Inspira- 
tions of  compressed-air  augment  the  pressure  in  the  en- 
tire arterial  system ;  expirations  in  rarefied  air  diminish 
the  pressure  in  the  aortic  system.  Lambert,  Ducrocq^ 
Riegel,  Franck,  Zuntz,  and  others,  by  a  carefully  con- 
ducted series  of  experiments,  arrived  at  opposite  results. 

Dujardin-Beaumetz,  m  summing  up  the  results  of  ex- 
perimentation, thinks  that  compressed  air  has  often  a  very 
bvorable  effect  on  the  respiration,  producing  a  current 
of  air  through  the  air-passages  which  clears  them  of 
macosities,  and  gives  to  the  pulmonary  parenchyma  a 
new  elasticity.  The  vital  capacity  is  augmented,  2ls  is 
shown  by  the  spirometer.  On  this  point,  Waldenburg  is 
in  harmony  with  all  other  experimenters.  As  for  the 
effect  of  compressed  air  on  the  circulation,  the  opinions 
are  so  contradictory  that  nothing  very  reliable  can  yet  be 
determined ;  it  is  by  no  means  demonstrated  that  this 
therapeutic  method  is  of  any  efficacy  in  diseases  of  the 
heart,  while  its  utility  as  a  respiratory  medicament  in ' 
chronic  bronchitis,  asthn^  emphysema  and  phthisis  is 
anquestioned. — ^Tit.] 

Experiments  on  animals  by  most  painstaking  observers, 
such  as  Einbrodt,  Hering,  Drosdorf,  Lambert,  Zuntz, 
have  cast  great  doubt  on  the  theory  of  Waldenburg, 
seemingly  so  reasonable.  Clinical  observations,  aided 
by  tracmgs  of  the  pulse,  have  confirmed  the  conclusions 
derived  from  physiological  experimentation.  These  ex- 
periflcienters  msule  use  of  the  kygnaogiuph,  a  sort  of 
manometer,  introduced  into  the  arteries  in  animals.  In 
al]  the  conditions  which  to  Waldenburg  indicate  an 
augmentation  of  arterial  pressure,  they  constantly  found 
a  lowering  of  vascular  tension.  Where  a  diminution  of 
pressure  had  been  noted  experimentation  showed  an  ex- 
cess of  pressure.  Waldenburg  sought  to  explain  this 
discordance  by  saying  that  the  tension  of  the  vessels  and 
mtiavascular  pressure  are  not  correlative  terms,  and 
that  sometimes  the  tension  of  the  arterial  walls  augments 
while  the  blood-pressure  diminishes.  He  sought  to  make 
this  demonstration  by  means  of  an  instrument  designed 
to  measure  the  degree  of  arterial  tension,  and  which  he 
called  a  "  pulse-shower  "  {montre  du  pouls).  The  down- 
&11  of  the  theory  was  nevertheless  complete. 

Clinical  and  sphygmographical  observations. — Clini- 
cal observations  have  conclusively  confirmed  the  results 
of  experimentation.  Riegel  and  Franck  distinguish  two 
opposite  periods,  the  one  of  the  initial  phenomena,  the 
other  a  final  period,  which  is  the  most  important.  Their 
results  agree  with  those  of  Ducrocq,  Drosdorf,  and  Zuntz. 
Omitting  the  somewhat  tedious  details  of  sphygmographic 
tradngs  (for  which  I  refer  you  to  my  work  on  **  Anoma* 
ioQS  Forms  of  Heart  Disease '')  these  careful  observers 
are  unanimons  in  affirming  that  the  first  effect  of  inhalar 
dons  of  compressed  air  is  to  produce  a  diminution  of 
intravascular  tension,  with  dimmution  of  the  frequency 
of  the  pulse ;  as  soon  as  the  atmospheric  pressure  on  the 
longs,  the  heart,  and  blood-vessels  diminishes,  the  blood- 
pressure  rises. 

It  results  from  these  observations  that,  while  Walden- 
burg taught  that  compressed  air  was  a  means  of  fortifying 
the  heart,  by  a  sort  of  regular  gymnastic  exercise,  the 
observers  cited  above,  and  especially  Oertel  and  Schnitz- 
Icr,  have  never  noted  such  effects,  especially  in  the  appli- 
cation of  pneumotherapy  to  diseases  of  the  heart. 

Dynamic  effects. — ^According  to  Sommerbrodt  and 
fiiedert,  the  intra-alveolar  air,  by  the  exaggerated  press- 
Bie  which  it  exerts  on  the  respiratory  mucous  membrane, 
produces  on  the  sensory  nerves  of  the  lungs  an  impres- 


sion which,  by  reflex  action,  excites  the  vaso-dilator 
nerves,  in  this  way  diminishes  the  vascular  tonicity,  di- 
lates the  blood-vessels,  and  lowers  the  pressure.  On  the 
other  hand,  the  inhibitory  nerves  of  the  heart  are  en- 
feebled, and  there  is  quickening  of  the  heart's  action  and 
of  the  peripheral  circulation ;  the  intra-alveolar  pressure 
thus  becomes  the  regulator  of  the  velocity  of  the  circu- 
lation. " 
Chemical  effects, — Every  change  of  pressure  in  the 
inspired  air  or  in  the  expired  air  determines  increase  of 
activity  in  the  respiratory  process ;  but  the  elimination  of 
carbonic  acid  is  always  more  marked  than  the  absorption 
of  oxygen,  so  that  more  oxygen  is  eliminated  than  was  in- 
troduced previously.  The  action  of  inspired  or  expired 
air,  then,  resembles  the  voluntary  augmentation  of  ordi- 
nary respiration,  and  the  modifications  ou^ht  not  to  be 
considered  as  the  result  of  more  energetic  oxidations, 
but  only  as  the  consequence  of  a  more  complete  diffusion 
of  ^as,  abstraction  being  made  of  the  muscular  action 
(which  is  of  little  significance)  during  this  more  active 
respiration.  These  facts  were  long  ago  pointed  out  by 
Paul  Bert. 

RAREFIED    AIR. 

Expiration  in  rarefied  air. — Expiration  in  rarefied 
air  produces  a  y^xy  distinct  sensation  of  retraction  of  the 
thorax.  The  abdominal  viscera  and  diaphra^  are  drawn 
upward  into  the  thorax  by  a  sort  of  aspu-ation.  The 
lungs  vare  very  thoroughly  emptied  of  their  atmospheric 
contents ;  even  large  quantities  of  residual  air  are  elimi- 
nated, from  five  hundred  to  two  thousand,  cubic  inches, 
and  even  three  thousand  in  the  emphysematous. 

It  is  easy  to  understand  that  by  reason  of  this  elimina- 
tion the  volume  of  the  lungs  is  reduced.  The  expelled 
iiir  issues  in  greater  volume  and  the  inspired  air  pene- 
trates with  greater  facility ;  the  inspiratory  muscles  are 
little  taxed. 

The  contraction  of  the  pulmonary  area  is  shown  bjr 
the  cyrtometer,  and  amounts  to  from  one  to  two  centi- 
metres of  circumferential  measurement.  The  retraction 
of  the  efMgastrium,  and  especially  the  elevation  of  the 
diaphrasm,  recognizable  by  percussion,  are,  moreover,  a 
proof  of  this  narrowing  of  the  field  of  respiration. 

By  lonf^  continuance  in  the  practice  of  expiration  in 
rarefied  air  an  increasing  augmentation  of  vital  capacity  is 
noted ;  this  may,  in  the  emphysematous,  amount  to  five 
hundred,  and  even  one  thousand  cubic  centimetres.  It 
is  easy  to  detect,  by  the  pneumatometer,  an  increase  in 
the  force  of  both  inspiration  and  expiration— the  latter 
by  virtue  of  the  less  resistance  which  the  elasticity  of  the 
pulmonary  tissue  and  the  muscles  of  expiration  have  to 
overcome. 

Effects  on  the  circulation  of  expiration  in  rarefied 
air. — These  are  similar  to  those  of  inspiration  in  free 
air.  The  venous  blood  more  readily  returns  to  the 
thorax. and  heart,  the  veins  are  emptied  while  the  tho- 
racic viscera  are  filled.  The  work  of  the  heart  becomes 
more  difficult  and  the  ventricular  systole  is  weaker,  pres- 
sure in  the  arterial  system  falls  and  the  arteries  are  less 
tense  and  more  compressible,  the  pulse  is  small  and  soft, 
and  while  the  lesser  circulation  is  overcharged,  the  greater 
circulation  is  poor  in  blood. 

The  nervous  system  is  more  irritated  and  reflex  vaso- 
motor action  is  more  marked  than  when  compressed  air 
is  breathed. 

Inspiration  of  rarefied  air. — This  ought  to  act  on  the 
circulation  like  inspiration  in  free  air,  and  like  expira- 
tion in  rarefied  air,  but  with  more  intensity.  It  is 
readily  understood  that  more  effort  is  required  on  the 
part  of  the  muscles  of  inspiration  to  introduce  the  neces- 
sary quantity  of  air  than  when  ordinary  air  is  breathed; 
hence  the  respiratory  muscles  become  strengthened  by 
a  sort  of  regular  gymnastic  exercise.  The  ventilation  of 
the  lungs,  according  to  Waldenburg,  is  diminished ;  ac- 
cording to  Speck  it  is  augmented. 

l^xpiration  in  compressed  air. — By  expiration  in  com- 


124 


THE   MEDICAL  RECORD. 


[August  2,  1884. 


pressed  air  the  expulsion  of  air  from  the  lungs  is  ren- 
dered more  difficult.  Here  the  muscles  of  expiration 
are  called  upon  for  more  work.  According  to  Speck, 
pulmonary  ventilation  is  augmented,  as  it  is  by  inspira- 
tion of  compressed  air,  for  although  an  obstacle  to  free 
respiration  exists,  this  is  overcome  by  the  enhanced  ac- 
tion of  the  breathing  muscles,  and  air  enters  in  great 
abundance.  The  organs  of  circulation  are  modified,  as 
by  inspiration  of  compressed  air. 

APPLICATIONS    OF   PNEUMOTHERAPY  TO  DISEASES   OF  THE 
HEART. 

Waldenbur^,  Henich,  etc.,  recommend  inspirations  of 
compressed  air  in  certain  cases,  directing  from  fifty  to 
one  hundred  inspirations,  of  yf^  to  -^  above  the  atmos- 
pheric pressure.  The  utility  of  these  inspirations  in  any 
form  of  heart  disease  is  doubtful.  When  you  have  a 
case  of  mitral  disease  with  perfect  compensation,  com- 
pressed air  is  not  necessary.  On  the  other  hand,  if 
compensatory  hyyjertrophy  has  not  commenced,  or  if  it 
is  insufficient,  compressed  air  removes  the  besoin  de 
respirer,  the  dyspnoea,  the  congestions  of  the  lesser 
circulation,  the  palpitations,  and  the  cyanosis.  This 
effect  may  be  far  more  lasting  than  the  period  of  in- 
spiration. During  the  inspirations  of  com|>res8ed  air  the 
excess  of  pressure  on  the  part  of  the  air  drawn  into  the 
lungs  causes  expulsion  of  the  blood  from  the  pulmonary 
vessels,  and  a  clearing  of  the  lesser  circulation.  Com- 
pressed air  is  then  useful  {a)  to  augment  the  systole  and 
the  arterial  pressure,  (b)  to  facilitate  the  passage  of  blood 
from  the  heart,  {c)  to  render  more  difficult  the  access  of 
blood  from  the  great  veins  to  the  heart,  and  thus  to 
free  the  lungs. 

In  these  cases,  says  Oertel,  it  is  preferable  to  expire 
in  rarefied  air,  for  then  the  vascular  pressure  and  the 
tension  of  the  arterial  walls  are  augmented  during  the 
entire  expiration,  and  stases  in  the  peripheral  veins  are 
prevented,  while  the  heart's  energy  is  promoted  by  a 
more  easy  diastole.  All  this  is  uncertain  and  theoretical, 
the  result,  it  must  be  confessed,  of  rather  hazardous  as- 
sertions, based  on  two  successful  cases  reported  by 
Henich  and  Schnitzler. 

Aortic  insufficiency  and  constriction. — In  both  aortic 
insufficiency  and  aortic  constriction  (according  to  Wal- 
denburg)  the  dyspnoea  is  diminished  because  the  intra- 
pulmonary  pres:ure  clears  the  blood-vessels  of  the  lungs, 
before  engorged ;  but  the  facts  cited  by  Waldenburg 
have  no  value. 

Fenoglio,  in  fact,  denies  the  utility  of  compressed  air 
in  these  afifections ;  he  thus  formulates  the  application 
of  pneumotherapy :  In  aortic  insufficiency  with  ex- 
cessive activity  of  the  left  ventricle  we  have  an  indica- 
tion for  expiration  in  rarefied  air.  We  hope  in  this  way, 
he  says,  to  diminish  the  exaggerated  compensation,  and 
he  cites  three  cases  in  support  of  this  method  of  treat- 
ment. Under  the  influence  of  these  expirations*  in  rare- 
fied air  he  has  seen  tension  enfeebled  and  the  arterial 
engorgement  lessened  ;  at  the  end  of  the  expiration  the 
sphygmographic  elevation  of  the  blood-wave  was  dimin- 
ished, the  line  of  descent  became  less  vertical,  and 
dicrotism  was  less  marked  Little  by  little  the  palpita- 
tions diminished  also,  as  well  as  the  painful  arterial  pulsa- 
tions and  the  feeling  of  anxiety  and  precordial  distress. 

Fatty  degeneration. — Several  cases  treated  by  Wal- 
denburg were  benefited  by  compressed  air. 

Pulmonary  cardiac  hypercemia^  with  hamoptysis. — De- 
spite the  theory  which  indicates  the  employment  of  in- 
halations of  compressed  air,  the  facts  are  opposed  to 
the  treatment,  and  hiemoptyses  are  certainly  to  be  feared. 

Resume. — ^There  is  no  precise  indication,  and  there 
are  everywhere  contra-indications  respecting  the  applica- 
tion of  aerotherapy  to  diseases  of  the  heart.  It  is  a 
question  yet  to  be  decided,  despite  the  rigor  of  the 
sphygmographic  explorations  of  Franck  and  Riegel  in 
their  researches  concerning  the  physiological  effects  of 
this  respiratory  method. 


HEPATIC  ALBUMINURIA. 
By  C.  C.  THAYER,  M.D., 

CLIFTON   SPKINGS,    N.  V. 

Albuminous  urine  always  signifies  a  patholo^cal  con- 
dition. That  pathological  condition  may  be  either  with- 
in or  without  the  kidneys  ;  it  may  be  entirely  local,'or 
may  be  general,  and  even  in  parts  far  remote  from  the 
kidneys.  It  may  be  inflammatory  or  mechanical,  nervous, 
organic,  or  functional. 

Traces  of  albumen  in  the  urine  are  far  from  being  a 
strange  phenomenon.  In  fact,  it  is  much  easier  to 
discover  albumen  in  the  urine,  than  accurately  to  define 
its  pathological  condition,  or  to  declare  its  significance 
when  found. 

In  the  year  1827,  when  Dr.  Richard  Bright  published 
his  "Medical  Reports"  on  albuminuria,  the  popular 
mind  naturally  drifted,  as  it  was  led  thereby,  to  consider 
albumen  in  the  urine  to  indicate  definite  pathological 
changes  in  the  kidneys  ;  and  while  we  cannot  justly  say 
that  this  distinguished  physician  unequivocally  declared 
that  albumen  in  the  urine  was  an  infailibie  s\ga  of  renal 
disease,  yet  in  his  enthusiasm  he  pressed  this  feature,  not 
too  far,  but  to  the  exclusion  in  a  great  degree  of  other 
and  equally  legitimate  phases  of  the  same  phenomenon. 

These  researches  and  reports  rekindled  and  intensi- 
fied a  deep  and  wide-spread  investigation  into  the  signifi^ 
cance  of  albuminous  urine. 

Christison,  Osborn,  and  othbrs  indorsed,  and  further 
elaborated,  the  theories  of  Dr.  Bright.  Fourget  reported 
albuminuria  as  dependent  upon  hypertrophy  of  the 
heart.  Solon  reported  albuminuria  as  dependent  on 
••obstruction  of  the  circulation,  peritonitis,  crises  of 
fevers,  cutaneous  affections,  pregnancy,  and  pneumonia." 
Graves  reported  albuminuria  as  dependent  on  "  chronic 
inflammation  of  the  liver,  phthisis,  and  diabetes "  (Con- 
tributions to  the  Physiology  and  Pathology  of  the  Circu- 
lation of  the  Blood,"  by  George  Robinson.  London,  1857). 
The  same  author  ^ves  this  proposition  :  "  That  the  pres- 
ence of  albumen  m  the  urine  is  produced  by,  and  its 
proportional  quantity  is  in  direct  ratio  to,  the  degree  of 
congestion  of  the  capillaries  of  the  kidneys,  from  what- 
eve:  cause  that  congestion  may  arise  "  TMoreland). 

Braun,  Frische,  Litzmann,  reported  albuminuria  as 
dependent  upon  "  mechanical  pressure ; "  Rayer,  Bee- 
quet,  on  "typhoid  fever;"  Copeland,  on  «* powerful 
blood  changes;"  West,  on  ** exanthemata ; "  Virchow, 
on  **  erysipelas."  **  It  is  known  that  the  urine  may  be- 
come temporarily  albuminous  in  consequence  of  an  ex- 
cess of  albumen  in  the  blood"  (Dickinson,  Wood's  Li- 
brary). 

**  These  different  views  are  not  reconciled  even  at  the 
present  time ;  whije  many  physicians  today  read  die 
term  albuminuria  as  an  equivalent  for  kidney  disease, 
there  are  others  who  attribute  some,  if  not  all,  such 
cases  to  an  altered  condition  of  the  blood  "  (Ziemssen's 
"Cyclopaedia,"  vol.  xv.). 

As  all  renal  diseases  do  not  produce  albuminous  urine, 
so  albuminous  urine  is  not,  per  se,  an  evidence  of  renal 
disease.  Among  the  varied  pathological  conditions  out- 
side the  kidneys  that  give  rise  to  albuminuria,  my  atten- 
tion has  been  called  of  late  to  two  cases,  where  daily 
examinations,  careful  investigations,  and  varied  tests 
seemed  to  prove  that  the  albuminuria  (in  said  cases)  was 
not  produced  by,  or  dependent  on,  any  pathological 
changes  in  the  kidneys  themselves,  but  upon  some  gas- 
tric or  hepatic  disorders. 

Case  I. — Mr.  K ,  merchant,  aged   twenty-four; 

nervous,  bilious  temperament,  mentally  depressed,  con- 
stipated, voracious  appetite,  palpitation,  throbbing  of 
arteries,  with  daily  excretions  of  albumen  in  the  urine. 

He  was  treated  as  follows  :  Hepatic  stimulants,  Turk- 
ish, salt,  and  electrothermal  baths ;  electricity  applied 
to  the  hepatic  region  produced  considerable  pain.  After 
one  week's  treatment,  some  specimens  of  urine  exhibited  a 
diminished  amount  of  albumen  ;  others  remained  the  same. 


August  2,  1SS4.] 


THE  MEDICAL  RECORD. 


125 


After  two  weeks  some  specimens  contained  none,  yet 
vithin  twelve  hours  the  usual  amount  would  reappear. 
He  was  still  eating  enough  for  two  well  men.  Diet  was 
DOW  cut  down  one-half,  when  a  marked  change  in  the 
orine  appeared.  Urea  increased ;  lithates  and  albumen 
dJiQioished.  Afler  two  months,  albumen  could  no  longer 
be  detected. 

Case  II. — Mr.  K ,  aged  thirty-five,  of  bilious  tem- 

pcraraent;  yellowish,  lead-colored,  rough,  and  dry  skin; 
poor  appetite,  constant  bad  taste  in  mouth ;  flatulence, 
and  constipated  from  youth.  For  months  has  had  no 
movements  save  by  the  use  of  extraneous  means,  and 
often  goes  a  week  without  being  able  to  secure  a  move- 
ment from  the  bowels.  Great  tenderness  over  the  liver 
and  epigastrium ;  subject  to  chills  and  often  night- 
sweats,  with  much  muscular  parn,  nervous  prostration, 
and  mental  depression ;  urine  scanty,  high  colored,  of 
big;h  specific  gravity,  and  loaded  with  lithates ;  albuncteo  1 
constant  and  clearly  marked.  He  gave  up  his  business 
last  October,  aind  consulted  Professor  Timothy  F.  Allen, 
of  New  York,  who  treated  him  one  month. 

He  then  consulted  Professor  E.  L.  Keyes,  who  took 
duufge  of  his  case. 

Was  brought  here  in  March  following,  with  the  above 
^ptoms.  He  was  put  upon  a  relaxing  and  depletory 
treatment,  Turkish  and  electro-chemical  baths,  alkaline 
salts,  and  amylaceous  food,  with  colocynth  and  hydrargy- 
rum pills  sufficient  to  secure  a  movement  from  the  bowels 
once  in  two  days,  with  stimulating  packs  over  stomach, 
bowels,  and  liver.  In  two  weeks  his  skin  and  color  be- 
gan to  dear  up,  and  in  three  weeks  there  was  not  a  trace 
of  albumen  in  the  urine;  had  gained  several  pounds  of 
flesh,  and  walked  around  very  well. 

Now,  while  there  has  been  constant  and  considerable 
albumen  in  the  urine  since  October  ist — ^seven  months — 
and  we  know  not  how  long  before,  we  have  been  unable 
to  discover  the  slightest  evidence  of  any  structural 
changes  in  any  of  the  renal  organs.  Where,  then,  must 
we  look  for  the  source  of  the  albumen  ?  Not  in  the 
oervoQs  system,  for  they  presented  neither  of  the  ner- 
lOfis  conditions  known  to  give  rise  to  albuminous  urine  ; 
DOt  in  any  organic  lesion  of  the  heart,  for  they  had  none ; 
Dot  in  any  febrile  condition  that  sometimes  for  a  limited 
season  produces  albuminous  urine ;  but  we  may  look  for 
ft  in  line  with  their  prominent  and  harmonious  symptoms 
of  gastric  and  hepatic  disorders.  We  may  search  for  the 
caufe  of  Mix  symptom  where  we  look  for  the  cause  of 
tiieir  other  symptoms.  That  the  albumen  is  associated 
with,  and  dependent  upon,  hepatic  and  gastric  disorders 
is  incontrovertibly  substantiated  by  the  positive  relief 
afforded  by  the  hepatic  and  gastric  treatment  employed. 
Tins  line  of  reasoning  is  abundantly  established  by  Prout, 
Cohnheim,  etc  Exactly  ^ow  albuminous  urine  is  pro- 
doced  in  these  cases  is  not  yet  clear,  but  the  fact  is  au- 
thorized by  Carpenter,  Bennett,  Dal  ton,  and  others.  The 
same  may  be  said  of  chyluria  and  glycosuria.  **  There 
are  also  reasons  for  believing  that  albuminous  urine  may 
be  induced  by  hepatic  derangements,  independent  of 
structural  disease  of  the  kidneys.  I  have  met  with  sev- 
eral instances  of  hepatic  colic,  but  where  there  was  no 
jaundice,  and  the  paroxysm  was  followed  by  a  temporary 
increase  of  lithates  and  albuminous  urine"  (Murchison). 
Dr.  Parices  ('*  On  the  Composition  of  the  Urine  ")  thinks, 
throagh  s<Hne  failure  in  the  preparation,  either  by  the 
stomach  or  liver,  crude  albumen  is  introduced  into  the 
drcnlation  and  excreted  by  the  kidneys.  Claude  Ber- 
nard found  that  crude  albumen  injected  into  the  jugular 
Tdn  produced  temporary  albuminuria.  "It  is  well 
known  that  if  two  or  three  raw  eggs  are  eaten  at  once, 
attmmen  makes  its  appearance  in  the  urine  "  (Fothergill). 
This  last  quotation  is  in  line  with  the  above  reasoning, 
bat  must  be  limited  to  cases  of  gastric  and  hepatic  dis- 
ofders ;  as  experiments  show  that  in  such  cases,  and  such 
only,  does  the  eating  of  raw  eggs  produce  albuminous 
mat.  To  test  this  truth  I  ate  at  one  meal  six  rare- 
oooked  e^s,  and  made  a  careful  test  of  the  urine  at  four 


and  eight  hours  afterward.  Then  I  ate  at  one  meal 
twelve  hard-boiled  eggs,  and  tested  as  before.  Then  I 
ate  at  one  meal  six  raw  eggs — in  all,  twenty-four  eggs  in 
twenty-four  hours,  but  not  the  slightest  trace  of  albumen 
could  be  found.  After  repeated  tests  of  this  kind  upon 
myself,  and  similar  oi^es  on  others,  I  assume  that  albu- 
minous urine  cannot  be  produced  where  there  is  a  healthy 
state  of  digestion  with  a  free  portal  circulation  ;  and  had 
Claude  Bernard  injected  crude  albumen  into  the  circula- 
tion on  the  other  side  of  a  healthy  liver  he  would  not 
have  found  it  in  the  urine.  Claude  Bernard's  experiment 
is  valuable  in  the  discussion  of  this  subject,  in  that  it 
shows  that  crude  albumen  may  be  excreted  in  the  urine. 
And  thus  we  are  brought  one  step  nearer  to  the  solu- 
tion of  this  question,  namely :  Mo/  albuminoids  passing 
through  the  digestive  process^  in  excess  of  the  pouters  of 
the  liver  to  deal  with  them,  may  produce  albuminous  urine. 
As  an  excess  of  lithates  in  the  urine  may  indicate  defec- 
tive powers  of  the  liver,  instead  of  defective  metamor- 
phosis of  tissue  (for  they  have  never  been  tissue),  so  albu- 
men in  the  urine  may  indicate  not  a  degeneration  of 
tissue  (for  it  never  was  tissue),  but  defective  metabolism 
in  "  liver  indigestion,"  and  both  are  aborted  proteids, 
wrecked  on  their  way  by  defective  digestion  and  assimi- 
lation. 

A  pertinent  question  here  arises.  What  is  the  charac- 
ter of  the  albumen  in  hepatic  albuminuria  ?  Is  it  egg 
albumen  (Fothergill)?  is  it  globulin  (Lehmenn)?  is  it 
a  peptone  (Lander-Brunton)  ?  If  it  were  egg  albumen, 
it  could  be  positively  distinguished  by  the  use  of  ether  in 
the  test  For  while  this  secretion  of  the  fowl's  oviduct 
resembles  albumen  in  the  blood-serum,  and  while  its 
action  under  heat  and  nitric  acid  is  virtually  the  same, 
yet  egg  albumen  is  precipitated  by  ether,  while  the  albu- 
men of  the  blood-serum  is  not.  If  it  were  globulin,  or 
"latent  mine  albumen,"  it  could  be  shown  by  the  use  of 
alcohol  in  the  test,  but  not  by  boiling  or  by  nitric  acid. 
If  it  were  peptones,  it  would  not  be  coagulated  by  heat 
or  nitric  acid  in  the  test. 

Traces  of  albumen  in  the  urine  are  often  unnoticed, 
because  of  imperfect  examinations. 

1.  The  test-tubes  should  be  perfectly  clean,  else  both 
the  character  and  appearance  of  the  urine  may  be  changed. 

2.  The  urine  should  always  be  rendered  slightly  acid 
by  the  addition  of  a  few  drops  of  dilute  acetic  acid,  as 
albumen  is  held  in  solution  in  alkaline  urine,  notwith- 
standing the  application  of  heat. 

3.  A  few  drops  only  of  nitric  acid  should  be  used,  as 
an  excess  of  it  redissolves  albumen.  Egg  albumen  is  not 
redissolved,  except  in  part,  by  an  excess  of  acid. 

4.  Latent  albumen  (Gerhardt)  is  not  discovered  by 
heat  or  nitric  acid,  but  is  precipitated  by  alcohol. 

5.  Albuminose  in  the  urine  is  not  coagulated  by  ether, 
heat,  or  nitric  acid,  but  only  by  the  metallic  salts  and 
alcohol  in  excess. 

6.  Albumen  in  the  urine,  first  rendered  slightly  acid,  is 
readily  discovered  by  the  addition  of  a  few  drops  of  a 
solution  of  potassium  ferrocyanide,  one  of  the  most  deli- 
cate of  tests. 

From  the  above  clinical  cases,  statistics,  and  consid- 
erations, we  draw  the  following  conclusions  : 

First, — Crude  albumen  in  the  circulation  may  be  ex- 
creted as  such  by  healthy  kidneys. 

Second. — Crude  albumen  in  the  circulation  may  arise 
from  a  retrograde  metamorphosis  of  albuminoids  in  the 
process  of  digestion  and  assimilation  from  liver  disease. 

Third, — Crude  albumen  in  the  circulation  may  arise 
from  a  luxus  consumption  of  albuminoids  in  excess  of  the 
capabilities  of  a  healthy  liver. 

Fourth, — Crude  albumen  in  the  urine  denotes  that  albu- 
minose, in  its  hidden  course  to  its  legitimate  and  ulti- 
mate end,  viz.,  fat  and  urea,  has  escaped  its  proper  des- 
tiny as  an  aborted  proteid. 

Fifth,  —Crude  albumen  in  the  circulation  denotes  not  a 
defective  metamorphosis  of  tissue,  for  it  has  never  been 
tissue,  but  a  defective  metabolism  in  tissue  construction. 


126 


THE  MEDICAL  RECORD. 


[August  2,  1884. 


The  Medical  Record-. 


A  Weekly  yournal  of  Medicine  and  Surgery, 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &.  Co.,  Nos.  56  and  58  Lafayette  Place. 

New  York,  August  2,  18^4. 

THE  BRITISH  MEDICAL  ASSOCIATION. 

The  meeting  of  the  British  Medical  Association  this  week, 
a  cabled  report  of  which  we  present  in  this  issue,  was 
a  remarkably  successful  one,  not  only  as  to  attendance, 
but  as  to  the  subjects  of  scientific  interest  which  were 
discussed.  In  point  of  numbers  and  representative  char- 
acter, there  is  probably  no  scientific  association  in  the 
world  that  is  its  equal.  Its  organization  is  so  simple  and 
withal  so  perfect  that  its  membership  embraces  the  lead- 
ing and  working  men  throughout  the  kingdom,  and  gives 
it  a  proportionate  influence  for  good,  not  only  with  the 
medical  profession,  but  the  public  at  large.  This  latter 
effect  is  in  no  small  degree  due  to  definite  and  concerted 
action  in  all  matters  not  only  pertaining  to  advance- 
ment in  medicine,  but  to  everything  scientific  and  sanitary 
which  effects  medical  legislation.  Hence  the  profes- 
sion of  that  country  naturally  look  to  the  Association 
for  such  expressions  of  opinion  as  shall  be  forcibly  direct 
as  well  as  widely  representative. 

It  is  a  matter  of  great  congratulation  with  its  many 
friends  that  the  Association  is  prospering  from  year  to 
year,  and  that  its  actual  membership  reaches  into  the 
thousands.  One  reason  for  the  latter  is  possibly  that 
there  is  no  other  organization  in  the  country  which  can 
claim  to  compete  with  it,  and  that  it  combines  in  its 
general  branches  every  element  for  effective  work,  and 
focuses  the  united  energies  of  the  most  progressive  medi- 
cal and  surgical  minds.  The  addresses — of  which  Dr. 
Redfem's,  in  the  present  issue,  is  a  type — are,  as  a  rule, 
models  of  their  kind,  showing  much  study,  patient  re- 
search, and  wide  grasp  of  the  subjects  treated.  This  is 
no  more  than  could  be  expected  considering  the  care 
with  which  the  orators  are  selected,  and  the  necessary 
incentive  for  the  best  efforts  on  the  part  of  the  gentle- 
men so  honored.  The  section  work  is  also  carefully 
looked  after,  and  not  only  are  the  topics  for  discussion 
systematically  advertised  in  advance,  but  the  proper 
men  are  duly  selected  to  present  them.  This  gives 
ample  opportunity  for  due  preparation,  and  naturally 
invests  the  scientific  proceedings  of  the  Association  with 
proper  interest.  The  addition  of  a  new  section,  on  thera- 
peutics and  pharmacology,  is  a  notable  feature  of  im- 
provement, and  gives  an  earnest  of  the  intention  of  the 
members  to  devote  themselves  to  the  study  of  a  branch 
of  our  science  which  has  of  late  been  too  much  neglected 
by  progressive  investigators.  There  is  already  promise 
of  much  good  work  in  these  branches,  and  the  impor- 
tance of  the  same  in  its  general  bearing  upon  the  future 


progress  of  medicine  was  properly  enforced  by  the  re- 
marks of  the  learned  president  of  the  Association  in  his 
annual  address. 

Probably  nothing  has  shown  the  influence  and  power 
of  such  an  Association  more  than  its  practical  demon- 
stration of  the  utility  of  systematizing  a  collective  inves- 
tigation of  disease.  By  means  of  its  extensive  machinery 
and  its  perfect  system  of  organization,  it  can  command 
the  means  to  an  end  which  cannot  be  equalled  by  any 
similar  body.  The  work  already  done  has  been  highly 
satisfactory,  and  we  opine  that  each  successive  year  the 
elaborate  report  of  the  committee  on  the  collective  in- 
vestigation  will  grow  .in  importance,  and  increase  in 
interest  accordingly.  At  least,  so  far,  it  shows  what 
can  be  done  in  a  proper  direction,  and  should  encourage 
similar  committees  to  surmount  what  are,  after  all,  only 
ordinary  obstacles. 

In  thus  reviewing  the  work  and  influence  of  the 
British  Medical  Association,  it  behooves  us  to  utilize,  in 
behalf  of  our  own  National  Association,  the  lessons  which 
it  teaches.     In  a  general  way  this  can  be  done  with  great 
profit  to  us.     There  are  certain  drawbacks,  in  regard  to 
organization   and   representative  character,  which  will 
however  be  next  to  impossible   to  surmount.     Great 
Britain  is,    comparatively   speaking,   a   small  country, 
and  concentration  of  medical  talent  within   a  reason- 
able area  is  not  impossible.     On  the  other  hand,  thou- 
sands of  miles  separate  the  members  of  the  American 
Medical  Association.     There  are  here  certain  elements 
that  militate  against  continuous  annual  attendance  upon 
the  meetings,  which  are  very  serious  ones  to  consider. 
Hence  it  follows  that  a  new  set  of  members  make  up 
the  majority  of  those  in  attendance  at    each  session. 
Some  attempt   has  been  made  to   overcome  this  ten- 
dency by  the  biennial  meeting  at  Washington,  but  even 
this  latter  city  is  by  no  means  central  in  location,  and 
cannot  be  reached  by  the  larger  number  of  delegates  in 
the  West  and  Far  West  without  great  expense  and  with- 
out serious  loss  of  time.     Again,  the  incentive  whicR  ob- 
tains with  our  British  brethren,  within  their  easy  travelling 
distances,  of  being  called  in  consultation,  does  not  exist 
with  the  larger  number  of  the  best  men  so  widely  scat- 
tered over  our  vast  territory.     Hence  the  tendency  is 
for  the  leading  men  in  different  parts  to  do  their  best 
work  in  their  district  societies,  and  as  a  rule  leave  the 
so-called  parent  association  to  take  care  of  itself  in  its 
own  way. 

It  can  hardly  be  necessary,  in  view  of  the  example  set 
us  by  our  cousins,  to  urge  the  necessity  for  a  better  pro- 
gramme for  section  work.  It  has  become  too  much  the 
fashion  with  chairmen  of  sections  here  to  seek  papers 
from  such  as  may  find  it  convenient  to  come,  rather  than 
from  such  as  should  feel  it  their  duty  to  come  and  con- 
tribute what  they  can  to  the  interests  of  the  sessions. 
There  was  an  exception  to  this  rule  in  some  of  the  sec- 
tions which  met  this  year  in  Washington,  notably  in  that 
of  the  Section  on  Medicine,  but  not  enough,  generally, 
to  give  us  very  sanguine  hopes  for  desirably  radical  de- 
partures. 

But  from  all  this  it  must  be  understood  that  our  best 
men  are  not  backward  in  doing  their  work  to  suit  their  own 
purposes.  Their  local  and  State  societies  absorb  a  great 
deal  of  this,  but  their  best  efforts  are  expressed  in  contribu 


August  2, 1884.] 


THE  MEDICAL   RECORD. 


127 


tioDS  to  our  leading  medical  jonrnals,  which  are  very 
properly  recognized  as  the  best  media  for  rapid  and  ex- 
tended communication  with  all  the  leading  centres^  and 
with  large  circles  of  appreciative  readers.  In  respect  to 
thus  utilizing  information  from  widely  scattered  regions, 
we  certainly  excel  our  cousins,  and  m  no  small  degree 
offset  the  necessity  of  a  national  association  for  the  dis- 
tribution of  intelligence  such  as  they  possess. 

But,  after  all,  how  to  practically  overcome  the  pecu- 
liarly inherent  difficulties  in  the  organization  and  work  of 
oar  own  association  is  not  an  easy  matter.  The  British 
example  cannot  be  followed  throughout,  for  reasons  al- 
ready suggested.  Interpreting  the  signs  of  the  times,  we 
may  say  that  the  tendency  in  this  country  is  toward  State 
rather  than  National  society  work. 


THE  SCIENTIFIC   GRANTS  REPORTS  OF  THE  BRITISH 
MEDICAL  ASSOCIATION. 

The  series  of  reports  from  committees  to  which  sums 
of  money  had  been  granted  by  the  British  Medical  As- 
sociation begins  this  present  year  with  the  report  of  Mr. 
G.  F.  Dowdeswell,  on  the  "  Intimate  Nature  of  Con- 
tagium  in  Certain  Acute  Infective  Diseases."  Mr. 
Dowdeswell  prefaces  his  report  with  a  review  of  the  pres- 
ent status  of  scientific  opinion  as  to  the  relations  of 
micro-organisms  and  infective  diseases. 

There  are  now  two  distinct  schools  of  schizomycolo- 
ffsAs :  one,  represented  by  Cohn,  Koch,  and  others,  up- 
bold  the  doctrine  that  a  difference  of  either  form  or 
fonction  is  sufficient  to  establish  a  distinct  species,  and 
ihat  these  different  species  are  constant,  and  do  not 
meige  into  each  other.  The  other  school,  represented 
bjrVon  Nagcli,  Billroth,  Lankester,  and  indirectly  by 
Pasteur,  contend  that  these  different  morphological  and 
]^ysiological  forms  are  merely  developmental  phases  of 
the  varieties,  brought  about  by  external  condition  of  a 
very  few  distinct  species. 

Mr.  Dowdeswell's  investigations  relate  largely  to  the 
above  points.  He  examined  experimentally  into  the  re^ 
ladons  of  micro-organisms  to  Davaine's  septicaemia,  and 
Pasteur's  so-called  septicaemia,  or  infective  peritonitis 
(also  known  as  Koch's  *' malignant  oedema'').  We 
wooki  remind  our  readers  that  the  specific  septicaemia 
of  Davaine  is  that  produced  by  the  injection  of  putrid 
Uood  into  the  subcutaneous  tissue  of  healthy  animals. 
Mr.  Dowdeswell's  experiments  showed  that  this  infection 
is  the  result  of  the  presence  of  a  special  pathogenic  or- 
g^mism,  resembling  d.  subtiiis^  that  the  disease  is  unques- 
tionably a  specific  septicaemia,  not  a  septic  intoxication, 
and  that  by  successive  inoculations  of  the  blood  of  one 
(fiseased  animal  into  another,  the  viruUnce  of  the  blood 
is  mi  irureased.  This  is  in  opposition  to  the  views  of 
Coze  and  Feltz,  and  of  Davaine,  and  so  far  as  it  goes 
tends  to  show  that  micro-organisms  do  not  change  in 
physiological  function. 

Pasteur's  septicaemia,  or  *' infective  peritonitis,''  is  a 
disease  produced  by  injecting  putrid  matter  into  the  ab- 
dominal cavity.  An  inflammatory  exudation  results,  con* 
taining  numerous  micro-organisms,  and  this  exudation 
vben  inoculated  in  other  animals  produces  serous  effu* 
sion,  sepdc  intoxication,  and  death.  Mr.  Dowdeswell 
(oand    as    had  Sanderson  and   Klein,   that  the  injec* 


tion  of  a  germ-free  chemical  irritant  into  the  abdominal 
cavity  also  excited  similar  infective  peritonitis.  The 
microorganism  developing  in  these  cases  had  already 
been  described  by  Koch,  who  called  it  the  "  bacillus 
oedematis,"  and  states  that  it  is  to  be  found  on  wet  soils 
and  is  a  conomon  saprophyte,  appearing  where  decom-- 
position  takes  place,  like  kacterwm  termo. 

Mr.  Dowdeswell's  conclusion  regarding  infective  peri- 
tonitis is  that  it  is  not  a  specific  septicaemia,  but  rather 
a  septic  toxaemia  in  which  the  micro-organisms  play  a 
subordinate  and  probably  mechanical  part  There  is  no 
increase  of  virulence  here  either  in  successive  inocula- 
tions. 

It  is  difficult  in  the  short  space  at  our  disposal  to  give 
any  fuller  account  of  the  report.  It  contains  much  else 
that  is  instructive  and  suggestive,  and  shows  its  author  to 
be  a  careful  and  judicious  investigator.  It  is  only  to  be 
regretted  that  the  work  was  not  pushed  a  little  farther  in 
the  lines  wherein  it  was  begun. 

The  second  report  is  that  of  Dr.  George  Thin,  upon 
<'  Leprous  Infiltration  of  the  Epiglottis,  and  its  Depend- 
ence  on  the  Bacillus  Leprae."  It  can  be  disposed  o^ 
very  briefly.  Dr.  Thin  believes,  if  we  understand  him 
correctly,  that  the  bacillus  leprae  is  the  pathogenetic 
agent  of  leprosy.  He  relates  the  history  of  a  case,  jand 
shows  specimens  illustrative  of  the  mode  in  which  this 
parasite  acts.  Its  special  home  is  the  lymph  or  white- 
blood  corpuscles.  It  migrates  with  these,  modifies  their 
activity,  causing  absorption  of  fibrous  tissue,  production 
of  tubercles,  and  a  low  grade  of  inflammation.  We  can 
hardly  agree  with  Dr.  Thin  that  sufficient  data  yet  exist 
to  enable  us  to  say  that  the  bacillus  is  the  cause  of  lep- 
rosy. His  contribution  to  this  subject  is,  however,  a 
most  important  one. 

Dr.  W.  North  makes  a  report  upon  the  '*  Influence  ol 
Bodily  Labor  upon  the  Excretion  of  Nitrogen."  His 
conclusions  have  already  been  published.  They  in  the 
main  corroborate  those  of  Dr.  Parkes,  and  disprove 
again  the  crude  investigations  of  Flint,  Jr.,  in  the  same 
direction.  We  must  say  of  Dr.  North,  however,  that 
his  work  is  very  blindly  and  unintelligibly  reported  in 
the  British  Medical  Journal. 


THE  PATHOLOGY  OF  THE  CERVICAL  SYMPATHETIC. 

Dr.  Paul  Julius  Mobius  has  written  an  elaborate 
monograph  (published  serially  in  the  Berliner  Klinischt 
Wochenschriff)  upon  the  pathology  of  the  cervical  sym- 
pathetic. This  interesting  but  mysterious  part  of  human 
anatomy  has  received  a  great  deal  of  attention  of  late 
years,  yet  its  exact  relations  and  functions  are  still  far 
from  being  satisfactorily  made  out.  Dr.  MObius,  besides 
giving  a  critical  review  of  previous  contributions,  furnishes 
something  new  in  the  shape  of  a  unique  case  of  paralysis 
of  the  cervical  sympathetic  produced  by  a  knife-stab. 
The  sharp  blade  entered  the  right  side  of  the  neck  just 
below  the  angle  of  the  jaw,  and  apparently  cut  the  sym- 
pathetic  cord  entirely  in  two.  There  was  very  little 
bleeding  and  the  wound  rapidly  healed,  but  the  patient 
soon  discovered  that  there  were  various  disturbances  of 
function  upon  the  right  half  of  his  face. 

His  right  eye  tired  easily,  and  became  sufiiised  with 
tears ;  the  pupil  was  smaller ;  the  lid-fissure  narrower ; 
the  ocular  skin-reflex  on  the  right  side  (/.^.,  the  widening 


128 


THE  MEDICAL  RECORD, 


[August  2,  1884. 


of  the  pupil  on  strong  irritation  of  the  skin  oi  the  neck) 
was  absent,  the  right  eye  was  more  moist  and  more  easily 
injected.  The  face  was  no  redder  or  more  congested  or 
moist  apparently  upon  the  right  side  than  upon  the  left ; 
but  slight  irritations  easily  produced  right-sided  flushings 
and  sweating.  The  temperature  in  the  right  external 
auditory  meatus  was  higher  than  that  in  the  left  (36.5** 
C.  to  35.6°). 

The  right  muse  risor.  Santor.  and  platysma  were  a  lit- 
tle paretic,  and  the  right  angle  of  the  mouth  hung  lower 
than  the  left.  The  heart's  action  appeared  normal  and 
the  patient  did  not  sufifer  from  vertigo,  tinnitus,  headache, 
or  sleeplessness.  He  did  have  at  times  a  disagreeable 
«ense  of  feeling  the  t)eating  of  his  heart.  Applications 
of  electricity  to  the  neck  produced  no  change  in  any  of 
these  symptoms. 

We  have  related  the  history  of  this  case  because  it 
shows  very  typically  most  of  the  phenomena  which  oc^ 
cur  in  one-sided  paralysis  of  the  cervical  sympathetic. 
Slightly  different  symptoms,  or  a  difference  in  predomi- 
nance of  special  symptoms,  naturally'occur  according  to 
the  location  of  the  lesion.  We  may,  however,  sum  up 
those  symptoms  which  have  been  found  in  the  cases 
reported  by  Seelifi:mailer,  Nicati,  Eulenburg,  Mitchell, 
and  others,  as  follows :  i.  Myosis  is  always  present  in 
the  eye  of  the  affected  side.  The  pupil  may  be  one-half 
or  twO'thirds  smaller  than  that  of  the  other  eye.  It  re- 
sponds to  light  and  to  acconmiodation,  but  its  motion 
may  be  slower  than  normal.  2.  Narrowing  of  the  pal- 
pebral fissure  through  paralysis  of  the  muscle  of  Muller 
is  almost  always  observed,  /.^.,  in  thirty-five  out  of  thir- 
ty-nine cases.  3.  Sinking  in  of  the  bulb  occurs  more 
rarely  and  is  a  later  symptom.  It  is  due  to  absorption 
of  orbital  fat,  and  to  paralysis  of  Mailer's  nmscle.  The 
tension  of  the  bulb  sometimes  becomes  less  and  the 
cornea  flattened.  4.  There  is,  quite  uniformly,  an  in- 
creased temperature  and  redness  on  the  affected  side 
of  the  face.  Sometimes  the  affected  half  simply  flushes 
very  easily  on  the  application  of  slight  stimuli.  A  few 
cases  have  been  reported  by  Nicati  in  which  the 
blanched  face  and  lowered  temperature  have  occurred 
along  with  the  eye-symptoms  of  paralysis.  5.  A  de- 
creased sweating  of  the  affected  side  often  occurs. 
•6.  Slight  trophic  changes  may  occur,  the  subcutaneous 
fat  becoming  absorbed,  but  it  is  doubtful  if  true  atrophy 
ever  takes  place.  In  paralysis  of  the  cervical  sympa- 
thetic on  one  side  the  heart's  action  is  not  slowed,  the 
thyroid  gland  is  not  enlarged,  and  there  are  no  distinctive 
cerebral  symptoms,  such  as  might  be  expected  to  oc- 
cur in  a  vaso-motor  paralysis  of  those  intracranial  ves- 
sels supplied  by  the  sympathetic. 

Dr.  Mobius  confines  his  attention  chiefly  to  the  subject 
of  sympathetic  paralysis,  and  seems  inclined  to  think  that 
this  includes  most  of  the  pathological  disturbances  of  the 
nervous  strands  in  question.  Only  thirteen  cases  of  true 
-sympathetic  irritation  are  cited.  In  these  there  was 
widening  of  the  pupil,  moderate  exophthalmus,  and  ac- 
<:ommodation  paresis,  coolness  of  the  face  on  the  dis* 
cased  side,  and  increased  heart's  action.  Seeligmiiller 
noted  a  flattening  of  the  cheek  and  dilatation  of  the  pupil 
in  two  cases. 

Mobius  Ycry  correctly  excludes  from  the  category  of 
cervical  sympathetic  diseases,  migraine,  Basedow's  dis- 


ease, angina  pectoris,  and  progressive  unilateral  atrophy 
of  the  face.  It  is  to  be  hoped  that  our  teachers  and  text- 
book writers  will  soon  become  sufficiently  advanced  in 
nervous  pathology  to  follow  Mobius'  example. 


THE  INFLUEItCE  OF  THE  CHOLERA  EPIDEMIC. 

No  one  can  doubt  that  the  present  epidemic  of  cholera 
will  have,  and  indeed  has  already  had,  an  immense  in- 
fluence for  good  in  the  sanitary  education  of  the  people. 
There  is  no  one  thing  about  which  doctors  disagree  less 
than  that  of  the  relation  of  filth  to  cholera.  And  every- 
thing in  the  history  of  the  present  epidemic  has  tended 
to  enforce  the  lesson  of  the  great  need  of  municipal  and 
individual  cleanliness.  Without  filth  no  cholera,  is  the 
motto  which  has  been  learned  from  the  past,  and  which 
has  for  the  last  six  weeks  been  steadily  inculcated  by 
medical  authorities. 

The  result  is  that  throughout  Europe  and  the  United 
States  there  has  been  an  amount  of  municipal  scrubbing 
which  is  quite  unprecedented  in  summer  history.  For, 
since  the  cholera  epidemic  of  1866  and  1873,  sanitary 
organizations  have  increased  in  number  and  effectiveness, 
while  the  people  have  been  educated  to  a  more  intel- 
ligent idea  of  their  functions  and  usefulness.  There  is 
no  doubt  that  the  extra  cleanliness  produced  by  the 
cholera  scare  will  effect  a  saving  of  life  from  other  filth 
diseases  far  in  excess  of  the  mortality  from  the  cholera 
itself,  unless  indeed  it  should  spread  beyond  all  expecta- 
tion. 

There  is  no  paradox,  therefore,  in  saying  that  the 
cholera  in  France  has  a  beneficent  side,  and  will  event- 
ually save  more  lives  than  it  destroys.  We  might  even 
assert  that  cholera  is  a  disease  which  the  people  cannot 
spare  quite  yet  from  the  world.  It  is  needed  as  an  edu- 
cator and  as  a  prophylactic  against  typhoid,  diphtheria, 
and  the  other  diseases  that  proceed  from  municipal 
fllthiness.  

THE  BATH  IN  MISSOURL 

« 

Dr.  W.  E.  Scott  relates  {Sf.  Louis  Courier  of  Medicine) 
the  case  of  an  old  Missourian  *'  who  hadn't  been  wet  all 
over  since  '63."  Following  up  with  inquiries  this 
alarming  suggestion  of  uncleanliness.  Dr.  Scott  reaches 
the  conclusion  that  there  is  not  one-third  of  the  people 
of  Missouri  who  average  one  bath  per  month,  and  agaun 
'*  there  are  at  least  fifty  per  cent,  who  do  not  take  a  full 
bath  from  October  till  the  month  of  May  ! "  This  con- 
dition of  things  is  not,  says  Dr.  Scott,  peculiar  to  Mis- 
souri.  In  these  days  of  "  health  hints,"  hygienic  hand- 
books, and  sanitary  propagandism,  it  is  rather  startling  to 
learn  that  in  the  very  home  of  "  Listerine  "  half  the 
people  do  not  bathe  from  fisill  to  spring,  v^ile  a  certain 
limited  number  have  not  been  wet  all  over  since  1863  1 


Suicide  of  an  Epileptic. — Medical  men  can  appre- 
ciate the  state  of  mind  which  had  been  reached  by  the 
young  man  who  shot  himself  in  this  city  last  week.  For 
a  number  of  years  he  had  suffered  from  epilepsy.  He 
had  been  treated  by  several  prominent  physicians,  but 
had  got  no  better.  He  found  himself,  on  the  eve  of  mar- 
riage,  a  confirmed  epileptic  with  no  hope  of  improve- 
ment held  out  and  so  he  killed  himself. 


August  2,  1884.] 


THE  MEDICAL  RECORD, 


129 


^ews  of  thz  ySSitsik. 


Yellow  Fevsr  is  said  to  be  increasing  at  Panama. 
It  has  also  appeared  at  Sonora,  Mexico,  and  is  spreading 
rapidly. 

Ah  Honor  to  Dr.  Hust£d. — At  the  Annual  Com- 
mencement recently  held  at  the  Syracuse  University,  the 
honorary  degree  of  LL.D.  was  conferred  upon  Dr.  N. 
C.  Hasted,  a  well-known  and  esteemed  physician  of 
New  York  City. 

Dr.  E.  W.  Jenks  was  the  recipient  of  a  cordial  recep- 
tion by  his  medical  brethren  on  the  occasion  of  his  return 
to  Detroit.  This  high  compliment  was  well  deserved, 
and  the  profession  of  that  city  did  itself  credit  in  tender- 
ing it 

The  Illinois  State  Board  of  Health  is  now  en 
gaged  in  revising  the  "  Register  01  Physicians,"  prepara- 
tory to  publication.    Any  changes  or  corrections  should 
be  promply  sent  to  the  Secretary.     Lists  of  the  officers 
of  the  medical  societies  in  the  State  are  also  requested. 

Annual  Meeting  of  the  National  Board  of 
Hkalth. — The  National  Board  of  Health  held  its  annual 
meeting  on  July  30th,  and  elected  officers  for  the  ensu- 
ing year  as  follows  :  President — Dr.  James  L.  Cabell,  of 
Virginia;  Vice-President — Dr.  Stephen  Smith,  of  New 
York ;  Secretary — George  E.  Waring,  Jr.,  of  Rhode  Isl- 
and \  additional  members  of  the  Executive  Committee — 
the  Hon.  Thomas  Simons,  Department  of  Justice ;  Dr. 
Charles  Smarts  United  States  Army,  and  Dr.  T^  S.  Verdi, 
of  Washington.  A  resolution  was  adopted  that  in  view 
of  the  possible  invasion  of  the  country  by  cholera,  and  of 
die  existence  of  epidemics  of  other  diseases,  and  in  view 
of  the  duty  imposed  upon  the  Board  by  law  to  obtain  in- 
formation on  all  matters  affecting  the  public  health,  the 
Executive  Committee  is  directed  to  put  on  duty  such 
members  of  the  Board  as  in  its  judgment  may  be  neces- 
sary. At  its  subsequent  meeting  the  Executive  Com- 
mittee directed  that  the  members  of  the  Board  be  placed 
on  daty  for  the  investigation  of  all  matters  which,  in  fheir 
jadgment,  have  a  direct  bearing  on  the  question  of  chol- 
en  as  a  present  menace  to  the  public  health,  and  epe- 
demic  of  other  diseases  existing  in  the  country.  Con- 
gress having  failed  to  make  appropriation  for  the  purpose, 
it  is  understood  that  such  duty  is  to  be  done  without 
compensation. 

Texas  Fever  among  Western  Caitle. — A  con- 
signment of  cattle  from  Indian  Territory  was  received 
It  Kansas  City  and  kept  in  the  stock  yards  in  that  city 
!or  some  days.  They  were  then  shipped,  part  to  Man- 
hattan, part  to  Chicago.  Of  200  sent  to  the  former  place 
over  30  died  of  what  seems  to  be  Texas  fever.  Of  500 
sent  to  Chicago,  a  large  number  were  attacked  with  the 
same  disease,  and  the  whole  herd  has  been  isolated  and 
killed. 

New  Facts  as  to  the  Cause  of  Death  by  Chix>- 
KOPORif. — Professor  K.  Winogradow  has  reported  to 
Wratsch  the  discovery  of  peculiar  changes  in  the  ner- 
voQs  ganglia  of  the  heart  in  a  person  who  died  from  the 
cfects  of  chloroform.  He  believes  that  they  throw  a 
Kw  light  upon  the  cause  of  death  in  these  cases. 


Honors  to  Medical  Men. — Professor  Le  Fort  and 
Dr.  Dumontpallier,  of  Paris,  and  Professor  Tourdes,  of 
Nancy,  have  been  given  the  cross  of  the  Legion  of  Honor. 
Dr..  Paul  Flechsig  has  been  made  ordinary  professor  of 
Mental  Diseases  at  Leipzig.  Professor  Longmore,  of  Net> 
ley,  has  just  been  elected  corresponding  member  of  the 
Acad6mie  de  Mddecine. 

The  most  Unique  Medical  Journal  at  present  pub» 
lished  is  probably  Le  Journal  Medical  Quotidien,  It  is 
published  daily,  as  its  name  implies,  at  Paris.  All  the 
matter  is  written  out  in  excellent  script,  and  this  is  then 
lithographed.     The  journal  is  autographic,  therefore. 

The  International  Otological  Congress. — We 
have  received  a  copy  of  the  programme  of  the  Third 
International  Otological  Congress,  which  meets  at  Mle^ 
Switzerland,  on  September  ist  to  4th,  1884.  Dr.  Alb. 
Burckhardt-Merian,  President,  is  also  chairman  of  the 
organization  committee.  A  list  of  thirty-nine  promised 
communications  is  given.  We  observe  that  no  Americans 
and  only  one  Englishman  are  among  the  contributors. 

The  Late  [Guiteau. — Dr.  Michael  J.  Madigan  has 
been  attempting  the  fresh  and  always  interesting  task  of 
proving  Guiteau  insane.  Dr.  Madigan  announces  him* 
self  to  be  a  cerebro-physiologist,  and  is  doubtless  very 
competent  to  tell,  all  too  briefly,  what  is  the  truth  about 
Guiteau.  We  venture  to  suggest  to  him,  however,  that 
he  has  a  singular  ignorance  of  certain  well-established 
logical  methods,  and  that,  for  instance,  he  can  never 
prove  Guiteau  insane  by  showing  that  the  editor  of  this 
journal  is  "only  a  surgeon."  For  the  rest,  the  single 
sensation,  aside  from  weariness,  which  this  young  man's 
polemic  excites  is  a  wonder  that  at  this  late  date  the 
Guiteau  question  cannot  be  discussed  without  person- 
alities and  passion. 

The  Death  of  Professor  Jager,  the  distinguished 
ophthalmic  surgeon,  of  Vienna,  is  announced. 

The  Treatment  of  Cholera  at  Marseilles  and 
Toulon  is  about  the  same,  according  to  the  Times  cor- 
respondent. In  the  first  stage,  twenty  drops  of  lauda- 
num are  given  with  three  grammes  of  ether,  and  ice  in 
the  mouth  to  stop  the  vomiting.  In  the  second  stage, 
from  ten  to  fifteen  grammes  of  acetate  of  ammonia,  the 
same  quantity  of  alcohol,  and  injections  of  morphia  are 
given.  If  the  patient  has  embarrassed  breathing,  oxy- 
gen is  inhaled  and  the  limbs  are  rubbed  with  turpentine. 
The  third  stage  is  the  cofiin. 

Progress  of  the  Cholera. — There  seems  to  be  no 
doubt  that  the  violence  of  the  cholera  is  abating  at  Mar- 
seilles and  Toulon.  The  deaths,  according  to  Consul 
Mason,  have  fallen  at  Marseilles  from  an  average  of 
sixty,  previous  to  July  2 2d,  to  between  twenty  and  thirty 
on  July  30th.  At  Toulon  the  daily  average  has  fallen 
from  forty  to  fifteen.  On  the  other  hand,  the  epidemic 
has  spread  to  numerous  small  places,  about  two  thousand 
in  all,  in  the  country  about  Toulon  and  Marseilles,  and 
has  appeared  in  an  active  form  at  Aix-les-Bains  and  at 
Aries.  The  disease  has  also  crossed  the  Italian  boundary 
and  appeared  in  several  small  towns  and  villages.  Up  to 
the  present  time  there  have  been  about  two  thousand  three 
hundred  deaths  in  France  from  cholera,  according  to  an 
estimate  of  Mr.  Harold  Frederic,  the  Nexv  York  Times 


I30 


THE   MEDICAL  RECORD. 


[August  2,  1884 


correspondent.  This  same  correspondent  has  furnished 
4L  very  clear  and  instructive  account  of  the  state  of 
affairs  in  the  cholera-stricken  cities,  and  shows  very 
clearly  the  intimate  relation  between  cholera  and  filth. 

Of  Toulon,  he  writes  :  "  The  city  itself  is  situated  on  a 
dat  plain,  four  feet  only  above  the  level  of  a  tideless  sea. 
The  consequences  arising  from  imperfect  drainage,  with 
a  natural  want  of  slope,  are  that  the  sewers  have  only  a 
fall  of  eighteen  inches,  so,  with  a  sluggish  movement, 
the  filth  of  the  town  drops  into  an  almost  stagnant  sea. 
What  is  worse  is  that  at  the  points  where  these  drains 
flow  they  are  only  covered  with  plank,  and  the  filth, 
disgusting  to  the  nose,  impresses  itself  on  the  eyes. 
Vou  not  only  then  smell,  but  you  see,  the  garbage  of 
Toulon.  Just  fancy  people  living  in  this  city,  of  quite 
eighty  thousand  inhabitants,  without  the  faintest  glim- 
mer of  common  sense  in  regard  to  public  hygiene  ! 
Toulon  must  be  inhabited  by  people  who  utterly  ignore 
«very  precaution  which  health  requires.  Their  habits, 
both  in  their  houses  and  in  the  public  streets,  are  in- 
describably filthy.  Toulon  has  always  been  a  breeding- 
place  of  disease.  Small-pox  when  it  broke  out  in  Tou- 
lon was  always  of  a  malignant  type,  and  more  difficult 
to  stamp  out  than  elsewhere." 

The  patients  at  the  hospitals  in  Marseilles  and  Toulon 
are  nearly  all  from  the  lower  classes.  At  first  nineteen- 
twentieths  of  the  patients  died ;  later,  the  mortality  be- 
came less  frightful. 

Dr.  Koch's  Report  to  the  German  Government 
on  the  cholera  epidemic  in  France  was  made  July  5th. 
The  disease,  he  says,  is  undoubtedly  of  Asiatic  origin, 
and  the  milder  form  of  the  malady,  spoken  of  by  Toulon 
medical  men,  is  nothing  but  severe  cases  of  diarrhoea. 
But,  in  reality,  writes  Dr.  Koch,  the  disease  is  of  a  very 
violent  form,  and  is  making  rapid  progress.  In  examin- 
ing the  bodies  of  some  patients,  he  found  the  cholera- 
bacillus.  The  fact  that  hitherto  the  plague  has  not 
spread  extensively  in  the  neighborhood  of  Toulon  is  due, 
he  thinks,  to  the  hilly  character  of  the  region,  which  was 
also  less  rapidly  and  severely  infected  on  the  occasion 
of  previous  cholera  epidemics  there.  Finally,  Dr.  Koch 
expresses  his  conviction,  based  on  past  experience,  that 
the  Asiatic  cholera  now  raging  in  the  South  of  France, 
will  also  extend  itself  to  the  Continent  of  Europe.  Im- 
mediately on  the  arrival  of  the  report  at  Berlin  the 
various  Federal  Governments  were  requested  to  take  the 
necessary  preventive  measures  against  the  spread  of  the 
•disease  to  Germany. 

Dr.  Koch's  Lecture  on  Cholera  at  Lyons. — At 
the  request  of  the  Lyons  authorities.  Dr.  Koch  while  in 
that  city  gave  a  free  lecture  on  cholera.  He  showed 
specimens  of  the  bacilli.  They  were,  he  said,  favored  in 
.growth  by  alkalies  and  killed  by  acidity  or  dryness. 
Three  hours  of  dryness  he  thought  mortal  to  them. 
They  were  inoffensive  in  the  lungs,  and  to  be  baleful 
should  be  carried  into  the  stomach.  Opium  he  thought 
the  best  for  early  treatment.  A  strong  stimulant  might 
be  useful  later,  but  he  was  not,  he  said,  able  to  indicate 
one.  Chloride  of  zinc,  sulphate  of  iron,  and  even  mer- 
cury, were  not  efficacious,  but  he  thought  carbolic  acid 
was.  Nevertheless,  he  often  washed  his  hands  in  Van 
Sweiten's  fluid,  which  contained  a  thousandth  part  of 


bichloride  of  mercury.     When  it  was  observed  to  him 
that  the  past  immunity  of  Lyons  from  cholera  was  at 
variance  with  his  theory  of  dryness,  the  climate  being 
damp  and  the  city  on  a  tongue  of  land  where  the  Rhdne 
and  Sadne  meet,  he  ventured  to  think  that  freedom  from 
epidemic  was   probably  due   to  the  excellence  of  the 
sewers.     At  the  same  time  he  feared  that  Lyons  was  too 
near  by  rail  to  Marseilles  and  Toulon  to  be  spared  this 
time.      Cholera  rarely  attacked  those  the  coatings  of 
whose  stomach  and  intestines  were  healthy.     There  was 
no  greater  predisposing  cause  among  the  healthy  than 
fear,  which  at  once   affected  these  organs.      Scouring 
floors  and  furniture  was  not  nearly  so  good  a  preservative 
as  polishing  and  frequent  dry  rubbing. 

A  Hygienic  Institute  in  Berlin. — It  is  proposed  to 
found  a  Hygienic  Institute  in  Berlin,  in  connection  with 
the  Berlin  University.  Professor  Koch  will  be  placed 
at  its  head. 

The  University  of  Heidelberg  is  about  to  celebrate 
its  five  hundredth  anniversary.  The  Baden  Parliament 
has  voted  $40,000  to  meet  the  expenses  of  the  occasion. 

Cholera  Curbs. — Naturally,  the  appearance  of  the 
cholera  in  Europe  has  led  to  the  revival  of  various  spe- 
cifics or  specific  methods  for  curing  cholera.     The  first 
to  be  brought  to  notice  was  the  use  of  oxygen  by  inhala- 
tion.    It  was  speedily  shown,  however,  that  this  agent 
did  little  or  no  good.    M.  Paul  Bert  has  revived  the 
claims  as  to  the  utility  of  copper  as  a  prophylactic  and 
curative  agent.     He  has  adduced  fresh  evidence,  as  he 
thinks,  of  its  value.     But  with  the  memory  of  the  deadi 
of  M.  Thuillier  still  fresh  in  mind,  it  will  be  hard  to  ex. 
cite  any  confidence  in  the  prophylactic  value  of  this  metal 
Prof.  S.  Samuel,  of  Kdnigsberg,  Prussia,  calls  attention, 
in  the  Berliner  Klinischer  Wochenschrift^  to  a  treatment 
of  cholera  recommended  by  him  a  year  ago,  viz.,  the 
subcutaneous  injection  of  warm  saline  solutions.     He 
admits  that  the  circulatory  apparatus  in  cholera  is  like  a 
sieve,  and  that  injections  directly  into  the  veins  are  soon 
lost :  but  by  injections  into  the  subcutaneous  tissue  of 
the  arms  and  chest  he  claims  to  have  obtained  excellent 
results.     He  cites  a  case  in  which  seven  ounces  of  water, 
and  subsequently  four  and  a  half  ounces,  were   thus  in- 
jected with  success.    The  treatment  by  applying  ice- 
bags  to  the  spine,  in  order  to  stimulate  (or  relax)  the 
ganglionic  centres,  has  also  been  again  brought  up  for 
discussion.    No  certain  conclusions  regarding  this  method 
have  yet  been  reached.     Among  other  "  cholera  cures  '• 
that  are  of  more  or  less  historic  interest,  are  :  the  injec- 
tion of  quinine  into  the  veins ;  the  plugging  of  the  anus ; 
the  actual  cautery  over  the  kidneys ;  and  the  administra^ 
tion  of  large  doses  of  sugar  (to  affect  endosmotic  changes 
in  the    intestines);    asafoetida,  capsicuni,  calabar  bean, 
quassite,  berberine,  naphtha,    phosphorus,   sulphur,  and 
various  antiseptics  have  been  at  different   times  recom- 
mended as  useful  in  cholera.    Finally,  Dr.  W.  C.  Seaman 
has  recently  advocated  in  The  Lancet  a  return  to  the 
use  of  calomel  in  gr.  x  to  gr.  xx  doses,  with  cold  affusions 
and  subsequent  friction. 

Dr.  Kidd's  Address  on  Obstetric  M kdicike,  de- 
livered before  the  British  Medical  Association,  is  unavoid- 
ably crowded  out  of  the  present  issue,  and  will  appear  in 
our  next. 


August  2,  1884.] 


THE  MEDICAL  RECORD 


lax 


FIFTY-SECOND  ANNUAL  MEETING, 

Held  in  Belfast^  Ireland,  Tuesday,  Wednesday,  Thursday, 
and  Friday,  July  2f),  30,  ^1^  and  August  1,  1884. 


(BY  DIRECT  CABLE  TO   THE  MEDICAL  RECORD.) 


Tuesday,  July  29TH — First  Day. 

The  Council  met  at  2  p.m.  The  first  general  meeting 
was  held  at  3  p.m.,  the  retiring  president,  Dr.  A.  T.  H. 
Waters,  of  Liverpool,  in  the  Chair. 

The  minutes  of  the  previous  meeting  were  next  read, 
as  aLready  published,  and  confirmed. 

RSPORT  OF   COUNCIL. 

Mr.  C.  G.  Whselhouse,  of  Leeds,  Chairman  of  the 
Council,  spoke  of  the  increase  of  membership  during  the 
past  year,  which  was  over  one  thousand.  The  total 
nmnber  was  now  nearly 

TWELVE  THOUSAND   MEMBERS. 

Veiy  few  members  had  died  during  the  past  year.  The 
Association  vras  now  in  a  prosperous  condition  with 

A  SURPLUS  IN  THE  TREASURY, 

aod  was  increasing  in  influence  and  in  representative 
character.  The  report  after  some  discussion  was 
adopted 

Mr.  C.  NCacNamara,  of  London,  was  then  elected 
Treasurer  of  the  Association ;  vice  Mr.  W.  F,  Wade, 
of  Birmingham.  Mr.  Wade  was  thereupon  elected  Vice- 
President  for  life. 

Dr.  McVail  made  a  motion  to  the  effect  that  the 
txaveUing  expenses  of  members  of  the  Council  be  paid 
\fj  the  Association.  A  long  discussion  ensued  in  regard 
to  the  propriety  of  such  a  measure.  It  was  contended 
that  as  each  branch  association  now  sends  a  member  to 
the  Council  that  the  aggregate  tax  upon  the  Association 
would  be  large ;  especially  would  this  be  the  case  with 
members  from  the  more  distant  parts  of  the  kingdom. 
The  pay  system  would  be  no  extra  inducement  for  at- 
tendance.    The  motion  was  finally  lost. 


First  Day — Tuesday — Evening  Session. 

The  Association  was  called  to  order  in  pursuance  of 
previous  adjournment. 

ADDRESS   OF   RETIRING   PRESIDENT. 

The  retiring  President,  Dr.  A.  T.  H.  Waters,  of 
Liverpool,  made  a  brief  address.  He  spoke  of  ihe 
dianges  that  had  been  made  in  the  character  of  the 
Council,  so  that  it  had  become  more  representative. 
He  believed  that  this  would  tend  to  increase  the  pros- 
perity of  the  Society.  He  congratulated  the  Association 
upon  its  continued  growth  and  present  flourishing  condi- 
tion. He  referred  briefly  to  the  subject  of  the  medical 
bin  which  had  been  before  Parliament  during  its  present 
sesaon,  and  had  been  the  subject  of  much  sharp  dis- 
cossion.  He  lamented  the  fact  that  it  had  been  with- 
drawn, and  that  the  prospects  for  medical  reform  were 


again  postponed.  In  conclusion,  he  thanked  the  Asso- 
ciation for  the  honor  it  had  paid  him  in  electing  him  to 
the  presidency. 

A  vote  of  thanks  was  then  tendered  the  retiring  pres- 
ident, carried  unanimously,  and  Dr.  Waters  was  elected 
Vice-President  for  life. 

Dr.  Waters  then  resigned  the  chair  in  favor  of  Dr. 
Cuming,  President-elect,  who  delivered  his 

PRESIDENTIAL   ADDRESS. 

Dr.  Cuming  gave  a  cordial  welcome  to  the  visiting 
members  on  behalf  of  the  profession  at  Belfast  He 
expressed  his  thanks  also  for  the  honor  paid  in  electing 
him  to  the  presidency.  He  ^hen  said  that  the  present 
epidemic  of  cholera  in  France  naturally  brought  up  the 
subject  of  the  sanitation  of  cities,  and  of  Belfast  in  par- 
ticular. The  sanitary  condition  of  Belfast  was  excellent 
except  that  the  sewage  polluted  the  harbor  to  a  some- 
what dangerous  extent. 

The  subject  of 

MICRO-ORGANISMS 

and  their  relation  to  disease  was  next  considered. 

Dr.  Cuming  contended  that  minute  organisms  under- 
went changes  in  character  as  do  other  animal  forms, 
and  in  that  way  very  likely  determined  the  character  and 
extent  of  epidemics.  The  old  term,  *'  epidemic  consti- 
tution," could  be  explained  on  this  theory  of  the  modi- 
fied life  of  micro-organisps.  But  in  addition  to  the  influ- 
ence of  micro-organisms  there  is  something  in  the  human 
body  which  modifies  vital  phenomena,  whether  normal 
or  abnormal,  and  this  was  the  diathesis.  That  there  was 
this  peculiar  modification  of  vital  activity  was  abundantly 
shown,  and  the  recent  studies  in  scrofula  and  phthisis 
had  still  more  strongly  confirmed  it. 

The  President  then  dwelt  upon  the  advantages  to  be 
expected  from  the  newly  created 

SECTION  ON   pharmacology  AND  THERAPEUTICS. 

Much  progress  was  now  being  made  in  these  branches, 
and  much  more  could  be  expected.  Medicine  could 
never  be  cultivated  in  the  same  lines  with  the  physical 
sciences.  There  are  too  many  elements  of  uncertainty 
or  too  many  complex  factors.  But  in  the  great  art  of 
relieving  and  preventing  suffering  more  and  more  was 
being  accomplished,  and  the  medical  profession  was 
every  year  becoming  one  of  more  dignity  and  usefulness. 

At  the  close  of  the  address  various  proposed  amend- 
ments to  the  by-laws  were  discussed,  but  no  important 
motion  was  carried. 

The  Association  then  adjourned  for  social  reunion. 


Wednesday,  July  30TH — Second  Day. 

The  meeting  of  the  Council  was  held  at  9.30  a.m. 

Dr.  Balthazar  Foster  was  elected  President  of  the 
Council,  vice  Mr.  Wheelhouse.  The  latter  gendeman 
was  elected  Vice-President  of  the  Association  for  life. 

The  second  general  meeting  was  held  at  1 1  a.m. 

Dr.  Lewis  A.  Sayre,  of  New  York,  gave  a  demonstra- 
tion of  the  application  of  the 

plaster  jacket 
in  diseases  of  the  spinal  column.     Dr.  Sayre  showed  the 


1^2 


THE   MEDICAL  RECORD. 


[August  2,  1884 


methods  of  applying  the  jacket,  and  asserted  the  ad- 
vantages of  it  over  later  so-called  improvements. 

Dr.  William  M.  Ord,  of  London,  delivered  the 
Address  on  Medif  ine.     His  subject  was 

SOME     PERVERSIONS     OF     NUTRITION     CAUSED     BY     THE 
NERVOUS   SYSTEM. 

Many  observers  of  late  years  had  been  contributing  evi- 
dence to  show  that  the  nervous  centres  have  a  remark- 
able power  over  the  processes  of  nutrition.  Charcot, 
Weber,  and  others  had  suggested  that  chronic  rheumatic 
arthritis  was  a  nervous  disease.  That  the  arthropathies 
in  tabes  dorsalis  were  produced  by  nervous  influence 
there  could  be  no  doubt.  The  speaker  suggested  that 
in  these  cases  there  was  probably  some  lesion  in  or  near 
the  anterior  cornua.  He  related  the  history  of  a  very 
interesting  case  of  progressive  muscular  atrophy  in 
which  there  was  a  joint  lesion. 

Dr.  Ord  referred  to  the  changes  in  opinion  which  had 
taken  place  by  reason  of  observations  like  the  foregoing 
and  a  closer  study  of  the  nervous  system.  When  Sir 
James  Paget's  book  first  appeared  it  was  laid  down  that 
all  general  diseases  were  of  blood  origin.  Now  it  could 
not  be  denied  that  this  view  must  be  greatly  modified. 
He  had  noticed  many  illustrations  of  the  reflex  and  direct 
influence  of  the  nervous  system  upon  nutrition.  He 
had  seen  uterine  congestion  produce,  reflexly,  irritation 
of  joints,  and  even  rheumatic  inflammation.  On  treat- 
ing the  womb  these  symptoftis  disappeared.  The 
speaker  also  instanced  cases  of 

URINARY  PARAPLEGIA, 

in  which  paralysis  was  produced  reflexly  by  disease  of  the 
urinary  organs.  The  influence  of  the  nervous  system 
upon  secretion  was  undoubtedly  a  very  marked  one  and 
showed  itself  in  a  variety  of  ways.  Fetid  breath  might 
be  the  result  of  a  secretory  dystrophy  or  nutrition  per- 
version. The  influence  which  mental  disturbances  have 
upon  the  secretion  of  milk  is  familiar  to  every  one.  The 
nervous  system  regulated  the  destruction  of  sugar  in  the 
body,  and  not  infrequently  exhausted  or  perverted  con- 
ditions of  this  system  resulted  in  temporary  '*  non-dia- 
betic '*  glycosuria.  As  this  often  occurred  in  persons  of 
a  gouty  tendency.  Dr.  Ord  suggested  the  term 

GOUT  OF  THE   LIVER. 

The  speaker  discussed  the  subject  of  the  relations  of 
myxoedema  to  the  nervous  system,  and  the  probability 
that  this  too  was  a  nervous  disease.  He  referred  to 
Kocher's  views  on  the  subject. 

Dr.  Ord  made  the  original  suggestion  that  the  thyroid 
gland  was  a  trophic  organ,  and,  perhaps,  ruled  the  nutri- 
tion of  the  nervous  system  in  a  measure. 

He  referred  in  graceful  terms  to  the  debt  which  was 
owed  to  Dr.  Weir  Mitchell,  of  Philadelphia,  for  his  con- 
tributions to  the  subject  of  the  nervous  system  and  nu- 
trition. 

At  the  conclusion  of  the  address.  Dr.  A.  T.  H. 
Waters  moved  that  a  vote  of  thanks  be  tendered  the 
speaker. 

The  motion  was  seconded  by  Dr.  Gairdner  and 
unanimously  carried. 

After  the  transaction  of  some  miscellaneous  business 
the  meeting  adjourned  for  the  day. 


REPORTS  OF  SECTIONS. 

SECTION  ON  SURGERY. 

Wednesday,  July  30TH — Second  Day. 

The  Section  on  Surgery  was  called  to  order  at  2  p.m. 
by  Sir  William  MacCormac,  President,  who  delivered 
an  address 

ON    ABDOMINAL   SURGERY, 

in  which  he  reviewed  the  advances  made  in  that  depart- 
ment during  the  past  few  years.  Every  part  of  heretofore 
forbidden  ground  had  been  boldly  and  successfully  at- 
tacked by  the  surgeon,  and  visceral  surgery  had  enlarged 
its  domain  of  applicability  beyond  the  most  sanguine  ex- 
pectations of  the  most  progressive  of  our  forefathers. 
He  particularly  referred  to  gastrostomy  as  an  operation 
which  had  for  itself  a  brilliant  future  in  properly  selected 
cases.  The  radical  cure  of  hernia  was  another  topic 
dwelt  upon  by  the  speaker,  who  cursorily  considered  the 
different  operations  and  the  indications  for  their  per- 
formances. The  removal  of  the  thyroid  gland  also  claimed 
attention  as  a  feasible  operation  in  many  cases  hereto- 
fore allowed  to  drift  along  unrelieved. 

Following  the  address  was  the  discussion  on 

THE    PLASTER-OF-PARIS    JACKET   IN   THE    TREATMENT    OF 
SPINAL  DISEASES, 

opened  by  Dr.  L.  A.  Sayrb,  of  New  York.  The  speaker 
demonstrated  the  principles  upon  which  the  jacket  was 
applied,  and  referred  in  a  general  way  to  its  superiority 
over  other  methods  of  fixation.  Several  additional  points 
as  to  detail  of  application,  were  brought  out  in  a  general 
discussion  which  followed.  His  remarks  were  well  re- 
ceived and  becomingly  appreciated. 

SECTION  ON  MEDICINE. 
Wednesday,  July  30TH — Second  Day, 

The  Section  was  called  to  order  by  the  President,  Dr.  ]. 
W.  T.  Smith,  of  Belfast,  who  delivered  an  address. 

The  subject  for  discussion  was 
albuminuria,  its   causes,    consequences,  diagnosis, 

AND  treatment, 

which  was  opened  by  Dr.  George  Johnson,  of  London. 
He  reviewed  the  subject  in  an  exhaustive  manner,  noting 
all  the  more  recent  advances  made  in  its  study,  particu- . 
larly  those  referring  to  diagnosis  and  treatment. 

In  the  discussion  which  followed,  a  letter  was  presented 
from  Sir  Andrew  Clark,  of  I^ndon,  calling  attention  to 
the  importance  of  recognizing  the  non-functional  fonus 
of  albuminuria.  These  he  thought  should  be  divided 
into  four  varieties,  hepatic,  oxaluric,  gouty,  and  nervous. 

ADDRESSES    BEFORE   THE    SECTIONS. 

The  other  addresses  before  the  Sections  this  afternoon 
were  respectively  as  follows  :  *'  Obstetric  Medicine,"  by 
Dr.  Clement  Godson,  of  London  ;  "  Ophthalmology," 
by  Dr.  W.  A.  McKeon,  of  Belfast ;  **  Physiology  and 
Pathology,"  by  Dr.  W.  S.  Greenfield,  of  Edinburgh; 
"Pharmacology  and  Therapeutics,'*  by  Dr.  Thomas  J, 
M aclagan,  of  London. 

In  the  evening  a  conversazione  was  given  to  the  mem- 
bers of  the  Association  in  Queen's  College  by  the  Presi- 
dent and  Executive  Committee.  This  was  largely  at- 
tended. 

(To  be  continued) 


August  2,  1884.] 


THE   MEDICAL  RECORD, 


133 


THE  MEDICAL  SOCIETY  OF  BERLIN. 

Stated  Meetings  June  25,  1884. 
Herr  Senator,  President,  in  the  Chair. 

(Special  Report  for  Thb  Mkdical  Record.) 

The   Society  having    been    called    to     order,    Herr 
ScHOLER  exhibited  a  case  of 

marked  retraction  of  the  conjunctiva. 

The  patient,  a  woman,  sixty-nine  years  of  age,  had  been 
in  excellent  health  up  to  within  about  three  years.  Since 
1881  she  had  had  two  attacks  of  pneumonia,  and  it  was 
at  one  time  feared  that  she  was  developing  a  pulmonary 
tuberculosis,  but  this  danger  was  now  past.  In  February 
d  this  year  she  had  what  appeared  to  be  a  simple  catar- 
rhal conjunctivitis,  for  the  relief  of  which  ordinary  astrin- 
gent lotions  were  employed.  The  swelling  and  redness 
did  not  subside,  however,  and  in  May  the  patient  applied 
to  Herr  Scholer.  He  found  the  conjunctiva  in  both  eyes 
evenly  suffused,  with  here  and  there  little  specks  of 
thickened  secretion.  There  was,  further,  a  very  marked 
contraction  of  the  fold  where  the  conjunctiva  is  reflected 
from  the  ball  of  the  eye  to  the  lids.  At  that  time  the 
contraction  of  the  superior  fold  was  not  so  great  but  that 
the  upper  lid  could  be  everted,  but  now  it  was  as  far  ad- 
vanced as  at  the  inferior  fold.  Cicatrix-like  bands 
could  be  seen,  but  there  were  no  adhesions. 

The  patient  gave  no  history  of  any  former  affection  of 
the  conjunctiva,  and  there  was  no  disease  of  the  eye  it- 
self The  cornea  was  perfectly  normal.  The  speaker 
said  that  there  were  but  two  recognized  conditions  in 
which  such  an  extensive  retraction  of  the  conjunctiva 
could  occur.  The  first  of  these  was  granulation.  But 
when  this  process  has  advanced  far  enough  to  cause  such 
an  atrophy  of  the  conjunctiva,  we  always  find  corneal 
opacities.  The  second  was  pemphigus  ;  but  here,  also, 
the  cornea  is  always  involved.  But  one  similar  case  has 
been  recorded,  the  account  of  which  was  published  by 
Alfred  Graefe*s  assistant  in  Halle.  Graefe  gave  to  the 
affection  the  name  of  essential  retraction  of  the  con- 
jnnctiva. 
Herr  Kobner  then  presented  a  patient  suffering  from 

lichen  ruber  planus, 

affecting  not  only  the  skin  but  also  the  mucous  mem- 
brane of  the  mouth  and  tongue.  The  patient,  a  woman, 
sixty  years  of  age,  had  had  a  hard  chancre  three  years 
before,  but  had  never  exhibited  any  secondary  symptoms. 
Two  months  ago  the  patient  noticed  a  number  of  little 
pmples,  looking  like  gnat-bites,  on  both  hands.  These 
itched  and  burned  considerably,  and  soon  spread  to  the 
extensor  surfaces  of  the  lower  part  of  the  forearms.  At 
the  same  time  it  was  stated  that  her  tongue  was  coated. 
The  eruption  now  was  thickly  spread  over  the  extensor 
surfaces  of  both  hands  and  forearms,  with  isolated  nod- 
ules on  the  soles  of  the  feet,  the  shoulders,  and  the  palm 
of  one  hand.  *  On  both  sides  of  the  anterior  portion  of 
the  back  of  the  tongue  was  a  row  of  dirty  white,  irregu- 
larly oval,  roundish,  or  polygonal  specks.  •  There  were  a 
few  very  small  nodules  here  and  there,  arranged  in  semi- 
circular groups.  On  the  inside  of  the  right  cheek  there 
were  numerous  whitish  specks,  arranged  in  the  form  of  a 
network,  and  some  similar  growths  on  the  red  border  of 
the  lower  lip.  The  patient  had  taken  about  half  an 
ounce  of  iodide  of  potassium  without  effect,  but  had  ap- 
peared to  improve  somewhat  since  the  administration  of* 
small  doses  of  arsenic. 
Herr  Virchow  read  a  paper  entitled 

syphilitic  joint  diseases. 

He  said  his  communication  occupied  nearly  the  same 
ground  which  was  gone  over  by  Herr  Giiterbock  in  his 
paper  read  at  the  meeting  held  on  June  nth,  but  that  he 
should  not  confine  himself  to  the  hereditary  fonn.  Syph- 
ilitic joint  disease  bore  no  slight  resemblance  to  arthritis 


sicca,  but  in  the  syphilitic  affection  there  was  always  an 
increase  in  the  amount  of  the  synovial  fluid.     The  seat 
of  the  lesions  is  the  same  as  it  is  in  arthritis  deformans. 
The  principal  changes  take  place  in  the  cartilage,  and 
consist  in  a  gradual  destruction  of  this  tissue,  sometimes 
advancing  so  far  that  the  cartilage  is  entirely  absent  in 
certain  portions.     On  the  other  hand,  however,  there  is 
this  difference  between  the  two  diseases,  namely,  that 
while  in  arthritis  deformans  the  cartilage  disappears  and 
exposes  the  bone,  in  syphilitic  arthritis  the  loss  of  sub- 
stance in  the  cartilage  is  replaced  by  a  coincident  forma- 
tion of  connective  tissue.     In  addition  to  this  cicatrix- 
like  development  of  connective  dssue  there  is,  in  the  worst 
cases,  a  villous  growth,  springing  from  the  borders  of 
these  ulcers  in  the  cartilage,  and  floating  free  in  the  fluid 
of  the  joint.     One  cannot  help  treating  these  lesions  as 
though  they  were  inflammatory,  although  they  appear  to 
be  atrophic.     The  new  growth  of  connective  tissue  at 
the  bottom  of  the  erosions  in  the  cartilage  recalls  tlie 
cicatricial  contractions  of  syphilitic  lesions  in  other  parts 
of  the  body.    The  author  had  never  had  the  opportunity 
to  examine  a  case  in  the  early  stage  of  this  disease,  but 
he  thought  it  not  improbable  that  there  were  in  the  be-i 
ginning  gummy  processes  at  the  points  where  the  above- 
described  lesions  were  found.     In  looking  at  the  articu- 
lar surfaces  one  would  almost  believe  that  pieces  of  the 
cartilage  had  sprung  loose,  so  sharply  defined  are  the 
edges  of  the  ulcerations.     They   are  found  usually  in 
the  central  parts  of  the  joint  and  not,  as  in  arthritis  de- 
formans, around  the  outer  surface.     Any  of  the  joints  may 
be  thus  affected,  and  undoubtedly  the  chsease  may  in  cer- 
tain cases  progress  so  far  that  the  whole  of  the  articular 
cartilage  may  be  destroyed.     The   author  exhibited  a 
number  of  specimens  showing  the  changes  described, 
and  related  briefly  the  histories  of  the  cases  from  which, 
they  had  been  taken.     And  he  concluded  from  a  study 
of  these  cases  that  there  existed  a 

CHRONIC    ARTICULAR    CHONDRITIS 

of  a  syphilitic  nature.  This  disease  resembled  most 
closely  arthritis  deformans,  yet  differed  from  it  in  some 
important  points.  In  the  latter  there  is  a  new  growth  of 
cartilage  tissue  about  the  edges  of  the  bones,  but  no 
such  change  takes  place  in  the  syphilitic  affection.  The 
disease  runs  its  course  without  suppuration,  in  which  it 
differs  from  the  other  fonn  of  syphilitic  arthritis,  some- 
times met  with  in  adults,  which  is  accompanied  by  sup- 
puration and  carries  off  the  osseous  structure. 

Herr  A.  Baginsky  related  a  case  of  the  hereditary 
syphilitic  joint  affection,  described  by  Giiterbock  at  a 
previous  meeting  of  the  Society,  which  he  had  observed 
in  a  child  thirteen  weeks  old.  In  addition  to  the  arthri- 
tis the  child  had  also  a  skin  eruption  and  pseudo- 
paralysis of  the  arm.     This 

pseudo-paralysis 

is  not  a  very  rare  condition.  The  speaker  met  with  two 
or  three  such  cases  on  an  average  every  year.  At  first 
sight  there  appears  to  be  a  true  paralysis,  for  the  affected 
limbs  hang  perfectly  motionless ;  but  a  more  carefiil 
examination  reveals  the  fact  that  we  have  to  do  with  a 
very  different  affectiota.  Both  the  diaphyses  and  epi- 
physes of  the  bones  are  thickened,  and  any  movements 
of  the  affected  articulations  cause  severe  pain.  The 
joints  are  swollen,  and  suppuration  sometimes  takes  place. 
Not  infrequently  the  articular  extremities  of  the  bones 
are  destroyed,  and  a  wobbly  joint  remains. 

There  is  still  another  form  of  joint  disease  in  young 
children,  in  which  there  is  nothing  to  indicate  that  it  is 
of  a  syphilitic  nature,  and  which  the  speaker  thought  was 
to  be  explained  on  the  theory  of  a  late  appearing 

puerperal  infection. 

The  affection  is  seen  in  children  three  or  four  weeks 
old.  There  is  first  infiltration  and  swelling  about  the 
joint,  later  suppuration  in  the  joint  itself,*and  finally  per- 


134 


THE  MEDICAL  RECORD, 


[August  2,  1884, 


foration.  Particles  of  bone  and  cartilage  may  even  be 
extended  through  the  opening,  and  yet  the  subsequent 
progress  of  the  disease  is  favorable.  In  one  such  case 
that  he  had  observed  there  was  perfect  restoration  of 
joint  motion,  so  that  the  child,  after  it  had  begun  to  walk, 
had  not  the  slightest  limp.     As  regards  the 

TREATMENT  OF   SYPHILITIC   JOINT  DISEASES, 

he  had  for  years  made  use  of  corrosive-sublimate  baths, 
to  the  exclusion  of  all  other  therapeutic  measures.  He 
used  seven  and  a  half  grains  of  bichloride  of  mercury  for 
each  bath,  and  gave  a  bath  every  day  or  every  other  day. 
Twenty  such  baths  suffice  to  bring  about  a  substantial 
improvement,  or  even  a  complete  cure,  in  some  of  the 
most  severe  forms  of  infantile  syphilis.  There  is  no 
necessity  for  giving  calomel  or  any  other  remedy  in- 
ternally, thus  saving  the  stomach  from  possible  injury,  a 
matter  of  no  small  importance  for  syphilitic  children. 

Herr  Henoch  said  that  the  director  of  the  children's 
clinic  in  Naples  had  recently  sent  him  his  work  on  the 
joint  diseases  in  hereditary  syphilis,  in  which  he  found  six 
cases  of  the  affection  described  by  Giiterbock.  It  seemed 
to  him,  however,  that  there  might  be  some  doubt  as  to 
the  syphilitic  nature  of  all  the  cases  there  given.  It  was 
possible  for  other  joint  diseases  to  occur  in  syphilitic  in- 
dividuals. He  could  not  understand  how  it  was,  if  these 
affections  were  so  common,  that  there  was  so  little  oppor- 
tunity to  observe  them  in  Berlin.  Of  the  immense  num- 
ber of  children  treated  by  him  for  hereditary  syphilis,  he 
had  never  yet  seen  one  with  syphilitic  joint  disease.  It 
was  true  that  he  had  had  one  patient  who  had  at  the  same 
time  arthritis  of  the  elbow  and  syphilis;  but  while  the 
other  symptoms  disappeared  during  a  course  of  specific 
treatment,  the  joint  disease  steadily  progressed.  He 
therefore  thought  it  fair  to  assume  that  the  arthritis  was 
non-specific  in  character. 

Herr  Hirschberg  asserted  that  he  had  oflen  seen 
the  joint  affection  of  hereditary  syphilis.  At  the  same 
time  with  the  characteristic  deformity  of  the  teeth,  there 
was  hydrarthrus  of  the  knee.  This  was  regarded,  not  only 
by  the  Germans  but  also  by  English  authors,  as  a  specific 
affection. 

Herr  Henoch  maintained  that  this  malformation  of 
the  teeth  was  no  indication  of  syphilis,  for  it  was  often 
observed  in  healthy  children,  and  was  as  frequently  ab- 
sent in  those  who  were  undoubtedly  syphilitic. 

Herr  Hirschberg  had  convinced  himself  that  Hut- 
chinson's assertion  on  this  point  was  correct.  All  syphilitic 
children  might  not  have  misshapen  teeth,  yet  when  the 
dental  deformity  existed,  it  was  a  certain  indication  of 
hereditary  syphilis. 

Herr  G.  Lewin  agreed  with  Herr  Henoch.  He 
thought  the  malformation  of  the  teeth  was  due  to  nutri- 
tive  disturbances  rather  than  to  syphilis.  Referring  to 
Herr  Virchow's  paper,  he  asked  if  the  lesions  there  de- 
scribed were  not  the  same  as  those  occurring  in  caries 
sicca.  He  was  inclined  to  believe  that  they  were.  The 
speaker  then  related  some  cases,  occurring  in  his  prac- 
tice, of  syphilitic  arthritis  in  both  adults  and  children. 

Herr  Scholer  held  to  the  views  advanced  by  Herr 
Hirschberg.  He  related  an  instance  of  joint  disease  in 
a  child  which  had  yielded  readily  to  specific  treatment. 

Herr  Sonnenburg  was  in  accord  with  Herr  Henoch 
in  the  opinion  that  syphilitic  arthritis  was  a  very  rare  af- 
fection. He  had  met  with  but  two  cases  in  his  clinic  in 
a  number  of  years.  He  considered  it  exceedingly  diffi- 
cult to  diagnose  these  affections,  since  there  were  no 
characteristic  symptoms.  He  had  seen  a  number  of  cases 
of  joint  disease  in  syphilitic  children,  but  they  resisted 
all  specific  treatment,  and  he  had  his  doubts  as  to  their 
syphilitic  nature. 

On  motion  it  was  resolved  to  postpone  further  dis- 
cussion until  the  next  meeting,  and  the  Society  then  ad- 
journed.   

Sugar- CURED  is  the  epithet  applied  by  Puck  to  the 
successful  results  of  homoeopathic  medication. 


THE  HOSPITALS    MEDICAL  SOCIETY  OF 
PARIS. 

Stated  Meeting,  June  27,  1884. 

M.  BucQUOV,  President,  in  the  Chair. 

(Special  Report  for  The  Medical  Rbcokd.) 

The  Society  having  been  called  to  order,  the  President 
announced  the  death  of  M.  Moreau,  of  Tours,  at  the  age 
of  eighty-one  years. 

A  somewhat  heated  discussion,  participated  in  by  a 
number  of  the  members,  then  followed  upon  the  questioa 
of  establishing  a 

STANDING  COMMITTEE   ON   EPIDEMICS. 

It  was  finally  decided  to  create  such  a  committee,  and 
the  President  appointed  MM.  Vallin,  Bucquoy,  Danlos, 
Du  Castel,  Labric,  Laveran,  and  Tapret. 

M.  Cadet  de  Gassicourt  presented  the  third  volume 
of  his 

TREATISE   ON   THE   DISEASES   OF   CHILDREN. 

He  desired  to  call  the  attention  of  the  menibers  especially 
to  the  chapters  on  meningitis  and  diphtheria,  two  subjects 
to  which  he  had  devoted  considerable  study.  He  had 
been  able,  by  the  study  of  ten  thousand  cases  seen  by 
himself,  to  correct  certain  statements  made  by  different 
authors  concerning  diphtheria. 
M.  Tenneson  then  exhibited  a 

PORTE-OUATE, 

or  cotton-holder,  for  making  local  applications  to  the 
cavity  of  the  uterus.  It  consisted  of  a  sound  which 
could  be  bent  in  any  desired  curve,  the  end  of  which 
was  provided  with  a  little  wad  of  cotton.  The  cotton 
could  then  be  dipped  in  any  medicinal  substance  and 
carried  into  the  uterine  cavity  without  necessitating  a 
previous  dilatation  of  the  os. 

By  means  of  this  instrument  M.  Tenneson  had  ob- 
tained good  results  in  the 

TREATMENT  OF   CHRONIC   METRITIS. 

The  local  treatment  of  this  disease,  he  maintained,  should 
not  consist  merely  in  the  cauterization  of  that  part  of  the 
uterus  which  could  be  reached  through  a  speculum,  for 
cervical  metritis  is  a  very  rare  condition.  Intra-uterine 
injections  may  cause  death,  and  the  introduction  of  a 
suppository,  to  be  left  in  the  cavity  of  the  uterus,  is  very 
apt  to  give  rise  to  an  excruciating  colic.  The  speaker 
thought  his  method  of  making  applicarions  was  su- 
perior to  all  others.  He  used  an  ointment  of  sulphate 
of  copper  (five  to  eight  parts  in  thirty)  or  of  white  pre- 
cipitate (two  parts  in  thirty)  in  preference  to  tincture  of 
iodine,  nitric  acid,  or  chloride  of  iron.  There  were  two 
contra-indications  to  this  mode  of  treatment  of  chronic 
metritis.  The  first  of  these  was  perimetritis.  In  the 
case  of  peri-uterine  inflammation  there  was  danger  of 
exciting  suppuration  in  cauterizing  the  mucous  mem- 
brane. It  was  also  necessary  to  omit  the  intrauterine 
applications  during  the  periods  of  acute  ^  exacerbation 
which  occur  so  frequently  in  the  course  of  chronic  metri- 
tis. Emollients  are  called  for  during  such  attacks,  and 
the  caustic  applications  should  not  be  resumed  until  the 
hypogastric  tenderness  has  entirely  disappeared,  and  the 
uterus  is  freely  movable  without  pain. 

M.  Martineau  thought  there  was  one  fatal  defect  in 
M.  Tenneson's  instrument — a  defect  common  to  all  sim- 
ilar appliances— and  that  was  that  the  cotton  on  the  end 
of  the  sound  was  not  covered.  In  its  passage  through  the 
^internal  os,  the  ointment  would  almost  surely  be  rubbed 
off,  and  thus  the  attempt  to  cauterize  the  raucous  mem- 
brane of  the  body  of  the  uterus  would  miscarry.  He  had 
devised  a  porte-caustique,  somewhat  similar  to  Lalleroanf  s 
instrument,  by  which  the  medicated  cotton  was  retained 
within  a  canula  until  it  was  fairly  within  the  internal  os. 

As  regarded  the  treatment  of  metritis  advanced  by  M. 
Tenneson,  he  thought  it  was  very  incomplete.  He  had 
seen  four  or  five  thousand  cases  of  metritis  in  the  past 


August  2,  1884.] 


THE  MEDICAL  RECORD. 


135 


six  years,  and  he  thought  he  knew  something  about  the 
disease.  The  lymphatic  spaces  of  the  mucous  mem- 
brane and  parenchyma  are  the  seat  of  inflammation. 
There  are  two  lymphatic  plexuses  in  the  posterior  part 
of  the  uterus,  and  it  is  there  that  the  affection  begins 
vbich  is  called  perimetritis,  or  pelvic  peritonitis,  but 
which  the  speaker  preferred  to  designate  as 

POSTERIOR  ADENO-LYMPHANGITIS. 

There  is  a  deeply  seated  induration  in  this  disease 

which  no  superficial  applications  can  reach,  but  which 
can  be  removed  only  by  stimulating  the  circulation  in 
the  part,  and  thus  promoting  the  absorption  of  the  exu- 
dation. Finally,  it  should  be  remembered  that  uterine 
inflammation  is  often  dependent  upon  a  diathesis,  which 
latter  is  amenable  to  general  treatment. 

*M.  Tenneson  preferred  the  term  perimetritis  as  one 
DOt  indicating  a  possibly  erroneous  pathological  concep- 
tion. He  was  prepared  to  admit,  however,  that  the  lym- . 
phatics  played  an  important  r6le  in  the  production  of 
the  diseases,  as  M.  Lucas-Championni^re  had  pointed 
out  The  speaker  had  not  asserted  that  local  treatment 
was  suflScient,  biit  had  spoken  of  the  general  therapeu- 
tic management  simply  because  that  was  not  included 
in  the  scope  of  his  communication.  But  he  desired  to 
protest  against  the  idea  of  a  diathesis.  Diatheses  were 
words,  and  nothing  but  words,  used  merely  as  a  cloak  for 
ignorance.  He  repudiated  the  term  and  the  conception 
which  was  sought  to  be  expressed  by  it. 

M.  Martineau  claimed  that  he  was  the  first  to  de- 
monstrate the  part  played  by  the  lymphatics  in  perime- 
tnds. 

M.  BuCQTJOY  thought  the  credit  of  priority  was  justly 
due  M.  Lucas-Championnidre. 

M.  Martineau  admitted  that  others  had  spoken  of 
lymphangitis  in  this  connection,  but  he  maintained  that 
he  had  studied  the  subject  more  carefully  than  they. 

M.  Du  Caste L  exhibited  a  specimen  of 

TUBERCULAR   MENINGITIS 

limited  to  the  paracentral  lobule.  This  was  now  the 
third  case  of  this  kind  that  he  had  seen,  and  he  believed 
that  this  was  the  usual  seat  of  localized  tubercular  men- 
ingitis in  the  adult. 

M.  BucQUOY  showed  a  patient  who  had  suffered  from 
an 

HYDATID   CYST  AT  THE    BASE   OF    THE    BRAIN. 

He  had  related  the  history  of  this  case  at  a  former 
meeting  of  the  Society,  and  some  discussion  had  been 
aroused  at  the  lime.  The  patient  was  now  perfectly  well. 

The  Society,  on  motion,  then  adjourned. 


^awzspon&enct. 


A  Medico-I^egal  Note. — A  decision  interesting  to 
physicians,  says  the  Philadelphia  Medical  Times^  was  re- 
cently rendered  in  the  courts  of  one  of  the  Western 
States.  Two  surgeons  had  been  employed  in  a  certain 
case,  but  in  different  ways  and  for  different  compensa- 
tions. The  patient  did  not  seem  satisfied  with  the  treat- 
ment, and  refused  to  pay  either  of  the  bills  rendered.  As 
a  result,  suit  was  shortly  brought  by  one  of  the  surgeons, 
and  defended  on  the  ground  that  the  services  were  of  no 
value.  The  court  held,  however,  in  favor  of  the  surgeon, 
and  judgment  was  given  for  him.  This  result  was  so  un- 
satisfactory to  the  patient  that  he  thereupon  began  a 
suit  for  malpractice,  and  one  of  the  defences  interposed 
was  that  this  question  had  been,  in  effect,  adjudicated  in 
the  previous  suit  and  could  not  be  again  raised.  This 
defence  the  court  held  to  be  a  good  one,  deciding  that 
the  former  suit  was  a  bar  to  the  second  one.  This  de- 
cision is  only  one  of  several  in  the  various  States  holding 
the  same  way,  so  that  a  physician  or  surgeon  need  not 
fear  a  direct  suit  for  damages  from  malpractice  if  the 
value  of  his  services  have  been  acknowledged  in  a  suit 
to  recover  the  amount  of  hi?  bill. 


OUR   LONDON   LETTER. 

(From  our  Spedal  Coirespondent.} 

MR.  HUTCHINSON'S  LECTURES  AT  THE  LONDON  HOSPITAL 
— EARLY  SYMPTOMS  OF  CANCER — MEDICAL  MEN  AND 
THE  TEMPERANCE  CONGRESS — DR.  RICHARDSON  ON 
PAINLESS  SLAUGHTERING — THE  NORTH  LONDON  CON- 
SUMPTION HOSPITAL — CHOLERA  AND  PRECAUTIONS 
AGAINST   IT — THEORIES  OF   THE   DISEASE — SMALL-POX. 

London,  July  xa,  X884. 

As  Emeritus  Professor,  Professor  of  Clinical  Surgery  Mr. 
Hutchinson  is  now  delivering  his  second  annual  course 
of  lectures  at  the  London  Hospital.  This  course  was 
instituted  last  year  on  the  occasion  of  Mr.  Hutchinson's 
retirement  from  the  acting  surgical  staff,  when  he  was 
appointed  consulting  surgeon.  It  was  considered  desir- 
able to  retain  him  as  a  teacher  in  connection  with  the 
Medical  College,  so  he  was  made  Emeritus  Professor, 
and  undertook  to  deliver  six  lectures  annually  on  some 
subject  connected  with  surgery. 

The  lectures  for  the  present  year  are  perhaps  a  greater 
success  than  those  given  last  summer,  and  being  wholly 
delivered  extempore  appeal  more  directly  to  the  minds 
of  the  auditors.  It  goes  without  saying  that  Mr.  Hutch- 
inson gives  no  mere  summary  of  ordinary  text-book  opin- 
ions, but  lays  before  his  hearers,  in  plain  and  unmistakable 
terms,  the  results  of  his  own  clinical  experience. 

On  Wednesday,  July  2d,  a  good  audience  assem- 
bled to  hear  the  lecture  on  "  The  Early  Recognition 
of  Cancer.'*  The  term  "cancer"  was  used  in  its  clinical 
sense  and  as  including  sarcoma,  and  not  in  its  limited  an- 
atomical sense  applying  solely  to  carcinomatous  growths. 
The  importance  of  its  early  recognition  was  obvious. 
Mr.  Hutchinson  said  that  before  the  actual  presence  of 
cancer  was  what  might  be  termed  the  pre-cancerous 
stage,  and  this  was  essentially  a  condition  manifested 
by  signs  of  local  inflammation.  An  interesting  case  was 
narrated  in  support  of  this  view.  It  was  that  of  an  old 
gentleman  whom  Mr.  Hutchinson  saw  in  consultation 
some  years  ago.  One  testicle  had  enlarged  and  was 
slowly  increasing  in  size.  The  surgeons  who  saw  the 
case  agreed  that  it  was  probably  not  malignant  and 
recommended  non-interference.  It  continued  to  grow, 
however,  and  was  at  last  removed  solely  by  request  of 
the  patient,  who  had  all  along  been  anxious  about  it  lest 
it  should  be' cancerous.  It  was  examined  microscopically 
and  was  found  to  be  simply  in  a  condition  of  inflamma- 
tory hyperplasia,  and  no  signs  whatever  of  malignancy 
were  discoverable.  The  patient  recovered  from  the 
operation,  no  further  trouble  manifested  itself,  and  his 
medical  attendants  came  to  the  conclusion  that  his  tes- 
ticle had  been  really  unnecessarily  removed.  Two  years 
elapsed.  The  remaining  testicle  then  began  to  enlarge 
in  the  same  way  in  which  the  other  had  done.  Remem- 
bering the  result  of  the  previous  operation,  the  surgeons 
strongly  advised  the  patient  against  operation.  As  be- 
fore, it  continued  to  enlarge  until  finally  it  reached  a  con- 
siderable size.  At  last  even  the  surgeon  began  to  be 
alarmed  and  the  patient's  anxiety  was  extreme.  The 
testicle  was  finally  removed  at  the  urgent  request  of  the 
patient.  It  was  examined  and  proved  to  contain  a  well- 
marked  sarcomatous  growth.  The  inference  was  that 
the  one  first  removed  would,  if  allowed  to  remain,  have 
also  acquired  a  sarcomatous  structure,  and  that  the  inflam- 
matory hyperplasia  found  was  a  condition  leading  up  to 
that  of  actual  malignancy. 

Eczema  of  the  nipple  preceding  cancer  was  an  illustra- 
tion. Mr.  Hutchinson  remarked  that  cancer  attacked  parts 
that  were  functionally  dead,  as  the  breast  in  women  late 
in  life.  Among  animals  it  attacked  the  cat,  the  dog, 
and  the  horse,  but  not  the  sheep.  The  two  former  ani- 
mals led  a  lazy  life  and  were  allowed  to  drag  out  their 


136 


THE   MEDICAL  RECORD. 


[August  2,  1884. 


existence  to  old  age.     Sheep  were  usually  killed  before 
they  were  old  enough  to  develop  cancer. 

The  practical  conclusion  Mr.  Hutchinson  drew  from 
his  view  was  to  treat  as  cancer  all  those  cases  where  you 
suspected  it — to  adopt  active  measures  at  once  and  not 
wait  for  '>iore  decided  symptoms  until  it  might  be  too  late. 

The  recent  Temperance  Congress  at  Liverpool  had 
what  may  be  termed  its  medical  side.  Several  medical 
men  took  part  in  it  and  read  papers  and  delivered 
speeches.  Dr.  Ridge,  of  Enfield,  made  some  rather 
startling  statements,  which  may  prove  of  importance 
should  further  research  confirm  them.  Dr.  Ridge  said 
he  had  been  able  to  sliow  by  experiment  that  alcohol  was 
injurious  to  the  health  of  growing  cells  in  direct  pro- 
portion to  the  quantity  to  which  the  cells  were  exposed, 
and  that  even  a  single  drop  of  alcohol  in  a  quart  of  water 
was  able  to  affect  them  injuriously  under  suitable  condi- 
tions. He  now  announced  that  he  had  found  that 
alcohol,  while  we  knew  it  to  be  an  antiseptic  in  large 
quantities,  was  really  a  septic  agent  in  very  small  ones, 
and  that  it  promoted  decomposition  of  animal  and 
vegetable  matter  with  bacterian  effects.  The  accompani- 
mentSyif  not  the  causes,  of  its  decomposition  flourished  and 
were  propagated  to  a  greater  extent  when  minute  quan- 
tities of  alcohol  were  present  than  when  the  decomposi- 
tion was  going  on  entirely  in  its  absence.  Below  one 
per  cent,  the  amount  of  alcohol  present  affected  in  pro- 
portion to  its  amount  the  degree  of  decomposition.  Dr. 
Ridge  deduced  from  these  facts  an  argument  against 
moderate  drinking. 

At  the  annual  meeting  of  the  Society  for  the  Preven- 
tion of  Cruelty  to  Animals  on  Monday,  July  7th,  Dr. 
Richardson  gave  an  interesting  account  of  the  researches 
he  had  made  to  discover  the  best  method  of  slaughtering 
animals  without  pain.  He  said  that  he  had  come  to  the 
conclusion  that  the  electric  shock  could  not  safely  be 
made  use  of  by  those  who  have  to  put  animals  to  death. 
He  had  made  experiments  with  various  anaesthetics,  and 
had  chiefly  employed  carbonic  oxide  gas  charged  with 
the  vapor  of  chloroform.  Dr.  Richardson  has  been  able 
to  make  experiments  on  a  large  scale  at  the  Dogs'  Home, 
Battersea.  Several  hundred  dogs  have  been  painlessly 
put  to  death  under  anaesthesia,  and  sheep  have  been  also 
killed  in  the  same  manner.  Dr.  Richardson  suggests 
that  the  method  should  be  employed  in  the  killing  of 
animals  used  as  food.  Painless  slaughtering  has  been  ad- 
vocated by  him  for  years,  and  now  that  an  easy  method 
is  withui  reach  we  may  hope  for  its  adoption. 

Another  inquiry  into  hospital  management  is  now  tak- 
ing place.  This  time  it  is  the  North  London  Consump- 
tion Hospital.  This  hospital  is  a  most  useful  institution, 
and  has  had  a  good  many  good  men  on  its  stafil  It  is 
satisfactory  to  find  that  the  errors  of  the  past  are  likely 
to  be  redeemed  in  the  future. 

It  is  reported  that  a  case  of  cholera  is  on  board  a  ship 
now  expected  at  the  port  of  Cardiff.  The  authorities  are 
quite  prepared,  and  will  not,  of  couse,  allow  any  case  to 
be  landed.  At  every  port  the  sanitary  authorities  are  on 
the  look-out.  The  various  hospital  authorities  are  be- 
stirring themselves.  In  view  of  the  fact  that  the  stress 
of  the  last  severe  epidemic  fell  upon  the  East  End,  and 
that  thus  the  London  Hospital  received  within  its  walls 
a  large  number  of  cholera  patients,  a  meeting  of  the  staff 
of  that  hospital  is  to  be  held  at  once  to  consider  what 
arrangements  should  be  made  in  case  of  another  epi- 
demic. 

Considering  the  probability  of  an  invasion  of  cholera, 
it  seems  a  pity  it  was  not  put  down  as  a  subject  for  dis- 
cussion at  the  approaching  International  Congress. 
Even  if  no  definite  rules  as  to  treatment  had  been  agreed 
upon,  we  might  have  acquired  some  more  distinct  notion 
of  its  nature  from  hearing  the  views  of  investigators  of 
various  countries.  The  water-carriage  theory  is  mainly 
held  in  England,  but  few  of  our  clinical  teachers  have 
had  the  opportunity  of  practically  studying  the  disease. 
In  India,  on  the  other  hand,  where  most  of  our  medical 


officers  have  had  cholera  cases  to  deal  with,  a  large  num- 
ber of  them  decry  the  water  theory  altogether.  The 
opinions  held  here  are  mainly  the  result  of  the  teachmg 
of  the  late  Dr.  Farr.  He  was  an  ardent  advocate  of  the 
water  theory,  and  all  facts  supporting  it  were  pushed  for- 
ward in  the  Reports  of  the  Registrar-General,  then  edited 
by  him.  Opposed  facts  received  at  least  scant  courtesy, 
and  many  accused  him  of  systematically  suppressing 
them.  The  opinion  of  the  Indian  observers  seems  at 
least  to  merit  a  better  hearing  than  it  has  yet  obtained. 

Small-pox  is  still  increasing.  Some  of  the  hospitals 
have,  in  consequence  of  the  prevalence  of  the  disease  in 
their  neighborhoods,  forbidden  in-patients  from  receiving 
visitors  as  usual. 


OUR  PARIS  LETTER. 

(From  our  Special  Correspondent) 

ANiESTHESIA  IN  CHILDREN  —  GERMAIN  ON  THE  GERM 
THEORY — HIS  OPPOSITION  TO  THE  SAYRE  PLASTER-OF- 
PARIS  JACKET — A  STRANGE  CIRCUMSTANCE  CONNECTED 
WITH  AN  EPIDEMIC  OF  MEASLES  AT  BOURG  ARGENTAL 
— A  WORM    IN   THE    EAR — CHOLERA   AT  TOULON. 

Paxis,  July  9,  X884. 

In  a  work  just  brought  out  by  Dr.  de  Saint-Germain,  he 
resumes  his  clinical  lectures  of  the  last  twelve  years  on 
different  points  of  infantile  surgery  which  came  under 
his  observation  at  the.  Children *s  Hospital  in  Paris,  of 
which  he  is  surgeon.  In  his  first  lecture  the  author 
treats  of  surgical  anaesthesia,  in  which  he  shows  that 
children  possess  no  greater  immunity  against  chloroform 
than  adults,  although  the  idea  is  entertained  by  some 
writers,  the  risk  being  the  same  in  both  cases.  Never- 
theless, M.  de  Saint-Germain  never  hesitates  to  employ 
chloroform  in  a  great  number  of  cases,  even  when  it 
appears  useless,  as  in  keratitis.  He  prefers  general  to 
local  anaesthesia,  even  when  the  latter  would  appear  to 
be  indicated,  as,  for  instance,  in  opening  abscesses,  in 
operations  for  ingrowing  of  nails,  etc.,  the  local  anaes- 
thesia being  as  painful  as  the  operation  itself.  More- 
over, in  the  case  of  children  one  would  have  to  fear  the 
reaction  after  the  application  of  cold.  He  employs 
chloroform  alone  ;  and  in  more  than  ten  thousand  cases 
in  which  he  practised  chloroformization  he  never  had  a 
single  death.  During  the  administration  of  chloroform 
M.  de  Saint-Germain  attends  exclusively  to  the  respira- 
tory rhythm  and  neglects  the  pulse,  which,  he  says,  gives 
indications  too  late  to  be  of  any  value.  The  heart,  it  is 
known,  dies  the  last. 

M.  de  Saint-Germain  often  employs  the  Ijsterian 
method  of  dressing  wounds,  but  without  the  least  en- 
thusiasm, and  he  expresses  himself  to  the  effect  that  the 
great  lesson  given  by  Lister  to  surgeons  was  to  teach 
them  how  they  were  to  wash  their  hands.  He  has  no 
faith  in  the  germ  theory  as  far  as  the  dressing  of  wounds 
is  concerned,  the  ancient  methods  appearing  to  him  suf- 
ficient in  the  great  majority  of  cases. 

According  to  M.  de  Saint-Germain,  children  do  not 
enjoy  immunity  even  against  cancer.  This  is  more  fre- 
quent in  boys  than  in  girls,  from  the  fact  that  cancer  of 
the  testicle  is  met  with  rather  frequently,  whereas  cancer 
of  the  ovary  is  very  rare.  The  forms  most  frequently  ob- 
served in  children  were :  the  encephaloid  and  the  fungus 
haematodes,  then  in  the  order  of  frequency  the  scirrhous 
form,  epithelioma,  and  finally  myosarcoma.  The  organ 
most  frequently  affected  with  cancer  is  the  eye,  and  the 
encephaloid  form  is  the  most  frequent.  It  is  primarily 
intra-ocular  and  begins  either  in  the  choroid  or  in  the 
retina.  The  treatment  consists  in  the  extirpation  of  the 
eye  as  soon  as  the  diagnosis  is  established ;  it  is  the  only 
chance  in  favor  of  the  patient,  and  yet,  .unfortunately, 
relapses  are  not  rare.  I  may  here  mention  that  Dr.  de 
Saint-Germain  is  vehemently  opposed  to  Dr.  Sayre's 
system  of  treatment  of  spinal  deformities,  the  plaster 
jackets  as  recommended  by  that  surgeon  being,  he  con- 


August  2,   1884.] 


THE  MEDICAL  RECORD. 


iZ7 


siders,  not  only  useless  in  these  cases,  but  positively  in- 
jurious, particularly  in  Pott's  disease. 

Dr.  Paul  Dagand  has  just  published  a  report  of  a  strange 
circumstance  connected  with  an  epidemic  of  measles  which 
prevailed  at  Bourg  Argental,  in  the  department  of  the 
Loire,  a  short  time  ago.     He  detected  the  presence  of  a 
large  quantity  of  round  worms  which  had  been  expelled 
from  the  stomach  and  bowels,  sometimes  numbering  as 
many  as  fifty.    In  one  case  a  worm  made  its  exit  through 
the  ear.    A  case  occurred  in  a  child  aged  seven  years, 
who  was  affected  with  the  measles.     The  child  had  been 
complaining  of  severe  pain  in  the  ear.     On  examination 
the  physician  noticed  something  which  to  him  looked 
like  the  remains  of  a  worm,  in  which  he  was  not  mistaken, 
as  on  trying  to  extract  the  object,  to  his  surprise  he  found 
after  its  removal  that  it  was  a  worm.     The  worm  meas- 
ured about  twelve  centimetres  in  length  and  two  milli- 
metres in  diameter.     The  child  had  passed  five  or  six 
of  these  helminths  by  the  mouth  a  few  days  previously, 
which  were  slightly  thicker  than  that  which  was  removed 
from  the  ear.     According  to  Dr.  Dagand,  the  worm 
pix)bably  passed  up  through   the  Eustachian   tube  and 
perforated   the  tympanum.     The  child,   who  was  seen 
again  a  fortnight  after  the  occurrence,  was  quite  well, 
with  only  a  slight  diminution  of  hearing  of  the  right  ear, 
which  was  the  one  affected.    In  getting  the  child  to  blow 
with  its  nose  closed,  no  communication  was  perceptible 
between  it  and  the  ear.     The  otorrhoea  which  existed 
tor  2l  few  days  after  the  expulsion  of  the  worm  had  dis- 
appeared.    This  case  was  brought  to  the  notice  of  the 
Medical  Society  as  a  curiosity  by  Dr.  Championni^re,  who 
remarked  that  though  the  case  was  very  interesting,  yet  it 
was  not  without  precedents.    In  the  article  "  Lombric,' '  in 
the  "Dictionnaire  des  Sciences  Medicales,"  Dr.Davaine 
reports  that  Winslow  discovered  a  worm  in  the  Eusta- 
chian tube  of  a  little  girl  on  whom  he  had  a  post-mortem 
examination.     One  extremity  of  the  worm  was  in  the 
pharynx,  while  the  other  was  entangled  among  the  bones 
of  the  tympanum.    Bruneau,  of  Amboise,  reports  another 
case  in  which  the  subject  was  a  young  woman,  from  whose 
ear  he  removed  an  entire  worm.     He  reports  also  that 
other  observers  had  detected  worms  in  other  parts  of  the 
body.    For  instance,  Rodriguez  and  Vrayet  each  relates 
a  case  of  worms  having  been  extracted  from  the  inner 
angle  of  the  eye.    Apropos  of  these  cases.  Dr.  Champion- 
ni6:e  observes  that  the  migratory  worms  should  not  be 
confounded  with  the  larvae  of  insects  which  have  some- 
times been  discovered  under  the  eyelids,  in  the  frontal 
sinuses,  in  the  ear,  and  in  the  nostnls,  and  which  might 
have  been  taken  for  entozoa. 

The  cholera  at  Toulon,  which,  as  you  are  aware,  broke 
oat  about  three  weeks  ago,  is  still  raging  with  varying  in- 
tensity in  that  town,  and  although  at  first  the  local  medical 
men  were  undecided  as  to  the  true  nature  of  the  epidemic, 
they  are  now  agreed  that  the  malady  is  indubitably  of  the 
Asiatic  type.  Dr.  Rochard,  Inspector-General  of  the 
Naval  Department,  and  Drs.  Brouardel  and  Proust, 
members  of  the  Council  of  Hygiene,  were  deputed  to 
report  on  the  nature  of  the  epidemic.  These  gentlemen 
gave  it  as  their  opinion  that  the  disease,  whether  im- 
ported or  not,  is  unmistakably  the  Asiatic  cholera,  though 
in  a  Yery  attenuated  form.  Dr.  Fauvel,  however,  the 
President  of  the  Consultative  Council  under  the  Minister 
of  Commerce,  and  who  never  went  to  Toulon  since  the 
outbreak,  is  singular  in  his  opinion  that  the  disease  is  of 
the  sporadic  type.  This  opinion  he  expressed  officially, 
not  only  in  his  report,  but  before  the  Academy  of  Medi- 
cine at  the  outbreak  of  the  epidemic,  and  to  which  he 
stil]  adheres,  on  the  grounds  that  it  is  not  nearly  so  viru- 
lent or  fatal  as  the  Asiatic  cholera.  Moreover,  it  is 
more  localized,  has  no  tendency  to  spread,  and  was  pro- 
duced by  purely  local  conditions,  which  are  of  the  most 
anti-hygienic  character  that  could  be  imagined.  How- 
ever, the  epidemic  has  spread  to  Marseilles,  but  Dr. 
Fauvel  thinks  that  it  will  go  no  further.  May  his  predic- 
tion be  realized.     Meanwhile  the  whole  country  is  in  a 


state  of  panic,  and  the  process  of  disinfection  of  men  and 
thin^  and  other  sanitary  measures  are  being  actively 
carried  out  

RATTLESNAKE  POISONING  IN  NEW  YORK. 

To  THE  Editor  or  Ths  Medical  Record. 

Sir  :  The  somewhat  unusual  occunence  in  New  York  City 
of  a  case  of  rattlesnake  poisoning,  and  its  unfortunate 
fatal  termination  having  furnished  a  popular  theme  for 
the  daily  papers,  it  may  not  be  uninteresting  from  a 
medical  standpoint  to  recite  the  history  of  another 
metropolitan  case  which  occurred  just  two  'years  ago, 
the  full  history  of  which  was  never  published.  At  that 
time  it  was  impressed  upon  me  that  there  had  been  no 
cases  in  New  York  City  for  eighteen  years  previously, 
the  victim  then  being,  as  were  also  the  two  recent  cases, 
a  showman.  The  occurrence  of  two  cases  in  two  years 
is  hardly  sufficient  to  make  us  apprehend  an  epidemic 
of  snake-bites  in  New  York,  or,  on  the  other  hand,  are 
the  cases  frequent  enough  to  destroy  interest  in  tiiem  as 
novelties  in  metropolitan  practice.     The  history  of  the 

case  I  have  to  report   is  as  follows :  E.  W ,  aged 

thirty-two,  a  showman,  entered  Ward  9,  Bellevue  Hos- 
pital, July  10,  1882.  As  the  proprietor  of  a  menagerie 
and  museum  then  exhibiting  in  the  Bowery  it  was  his 
custom  every  evening  to  study  the  habits  of  a  collection 
of  a  dozen  rattlesnakes  he  had  confined  in  a  cage. 
Being  careless  in  the  handling  of  one  of  the  larger  ones, 
it  struck  at  his  hand,  severely  wounding  his  thumb  in 
several  places.  The  wounds  were  deep  and  the  fangs 
had  full  opportunity  to  exert  their  influence.  He  imme- 
mediately  commenced  to  suck  the  wound,  and  sent  for 
whiskey.  Before  it  arrived  evidences  of  constitutional 
infection  were  apparent.  He  complained  of  fulness  in 
the  head,  vertigo,  impairment  of  vision,  and  great  pros- 
tration. He  drank  copiously  of  the  whiskey  and  con- 
tinued to  suck  the  wound.  On  entering  the  hospital, 
the  hand  and  arm  presented  to  us,  who  had  never  before 
seen  a  snake-bite,  a  most  peculiar  appearance.  They 
were  greatly  swollen,  hard  and  tense  and  had  a  strange 
mottled  discoloration  extending  to  the  shoulder.  The 
color  was  a  yellowish  green,  and  figured  in  a  manner 
best  described  by  the  term  mottled.  He  was  delirious, 
undoubtedly  in  part  due  to  the  whiskey,  the  tongue  was 
dry  and  brown,  and  he  suffered  greatly  from  thirst.  He 
was  in  marked  shock,  verging  on  collapse,  and  for  twenty- 
four  hours  it  was  doubtful  if  he  would  survive,  but  to  the 
vigorous  treatment  employed  I  think  his  recovery  can 
undoubtedly  be  ascribed.  Moderately  free  incisions 
enlarged  the  wounds,  and  to  these  firee  applications  were 
made  of  strong  aqua  ammonia,  and  into  the  hand,  fore- 
arm, and  arm  a  solution  of  carbonate  of  ammonium  was 
injected.  This  was  given  for  both  its  local  and  its  con- 
stitutional effect.  Poultices  of  flaxseed  and  charcoal, 
enveloping  the  entire  limb  were  applied  and  frequently 
changed.  Diaphoretic  and  diuretic  mixtures  were  given, 
together  with  the  joint  administration  of  carbonate  of 
anunonium  and  phenic  acid,  then  under  trial  in  the  hos- 
pital. Just  how  much  resulted  from  the  use  of  the  latter 
cannot  with  accuracy  be  estimated,  but  to  the  ammonium 
the  major  part  of  the  credit  is  given.  After  a  very  criti- 
cal stage  of  twenty-four  hours  he  began  to  improve,  and, 
barring  a  tedious  convalescence,  did  well. 

Gangrene  of  the  thumb  supervened,  rendering  neces- 
sary amputation.  The  mottled  look  of  the  limb  remained 
for  some  weeks. 

Another  example  of  novelties  in  city  practice  are 
tarantula-bites,  of  which  I  have  had  two  cases,  both 
occurring  in  men  engaged  in  unloading  bananas  from 
West  India  fruiters.  The  symptoms  were  similar  in 
character  to  snake-bites,  but  much  less  severe  in  degree. 

Eraser  C.  Fuller,  M.D. 

234  West  Fifty-ninth  Street, 

July  X5,  X884.         

**  Small  Fevers  Thankfully  Received  "  is  a  motto 
suggested  to  a  young  physician  by  Dr.  Holmes. 


138 


THE  MEDICAL  RECORD. 


[August  2,  1884. 


THE  USE  OF   PEPTONIZED  MILK,  AND  HOW 
TO    MAKE   IT. 

To  THE  Editor  op  The  Medical  Record. 

Sir  :  A  formula  for  a  food,  as  well  as  for  a  medicine,  will 
certainly  disappoint  one  who  wishes  to  try  it,  and  it  may 
do  much  harm,  if  it  be  wrongly  stated.  In  my  note  to 
you  on  peptonizing  milk,  the  word  grains  has  in  three 
places  been  printed  grams  or  grammes,  thus  making  the 
quantities  fifteen  times  too  much.  The  sentence,  "  Mix 
a  powder  consisting  of  five  grammes  of  Fairchild's  ex- 
tractum  pancreatis,"  etc.,  should  be,  **Mix  a  powder 
consisting  of  five  grains,"  etc.  In  the  letter  from  Pro- 
fessor Leeds/ ^  i^  grams  of  extractum  pancreatis  and  4 
grammes  of  sodium  bicarbonate,"  should  read,  "  i^  grains 
of  extractum  pancreatis  and  ^  4  grains  of  sodium  bicar- 
bonate." In  justice  to  Professor  Leeds  as  well  as  myself, 
please  publish  these  corrections. 

Yours  truly,  J.  Lewis  Smith,  M.D. 

New  York,  July  ai,  1884. 


A  PROBLEM,  ETHICAL  AND  MEDICO-LEGAL. 

To  THE  Editor  op  The  Medical  Record. 

Sir:  An  unmarried  woman,  about  forty-five  years  o 
age,  of  spare  frame  and  delicate  nervous  organization, 
is  now  suffering,  as  she  has  formerly  done  after  various 
intervals  in  her  life,  with  hysteria,  accompanied  by  some 
emotional  and  mental  aberration,  and  exhibiting  a  ten- 
dency under  her  present  management  to  confirmed  in- 
sanity. Without  medical  advice  or  direction,  her  family 
have  locked  this  poor  woman  up  in  a  small  room,  have 
put  strong  and  gloomy  looking  oak  bars  across  the  win- 
dows, have  left  her  much  of  the  time  alone  in  the  room, 
without  a  bed,  chair,  carpet,  or  show  of  comfort,  having 
only  an  angular  and  uncomfortable  lounge  to  lie  on,  and 
have  provided  her  with  no  regular  attendant,  medicines, 
or  physician.  She  has  been  sleepless,  almost  without 
appetite,  and  having  a  pulse  of  feverish  and  excited 
character.  It  is  doubtful  whether  she  has  been  provided 
with  suitable  and  sufficient  food.  She  has  been  treated 
to  a  strait-jacket  several  times,  and  the  amateur  direct- 
ors of  her  case  have  sought  diligently  among  the  physi- 
cians of  the  town  to  have  her  bled  freely,  but  none  would 
do  the  job.  In  none  of  these  attacks  has  she  ever  ap- 
peared dangerous,  her  most  offensive  freak  (except  some 
harsh  talk  about  her  relatives)  consisting  of  a  break  for 
liberty,  at  night,  perhaps  not  too  well  clad,  and  this  not 
recently,  but  at  one  or  two  former  periods,  before  this 
present  demon-baiting  system  was  adopted.  The  friends 
of  this  poor  woman  think  themselves  intelligent,  liberal- 
minded,  even  benevolent  They  are  financially  able  to 
procure  comforts  and  help  for  their  afflicted  relative. 

Now  for  the 

Problem. — What  is  the  social  and  ethical  duty  and 
legal  power  of  remedy  in  the  above  case,  possessed  by  a 
neighbor  and  physician  who  knows  and  can  prove  facts 
as  stated  ?  Can  it  legally  be  that  such  neglect  of  skilled 
advice  and  treatment,  and  such  an  active  course  of  medi- 
eval or  barbarous  management  be  adopted  and  pur- 
sued upon  the  mere  whim  and  guidance  of  unmedical 
and  relentless  friends  (?)  of  the  invalid  ?  Has  the  edu- 
cated and  humane  onlooker  no  power  to  interfere  in  the 
defence  of  outraged  personal  rights  and  for  the  correc- 
tion of  abused  nature  and  health  of  mind  and  body?  An 
early  answer  will  oblige  Humanity. 


-,  Pennsylvania,  July  Z9,'x884. 


[The  law  of  Pennsylvania  is  that  insane  persons  may 
be  placed  in  a  hospital :  "  On  statement  in  writing  of 
any  respectable  person  that  a  certain  person  is  insane 
and  requires  restraint,  the  judge  shall  appoint  at  once  a 
commission  to  inquire  into  and  report  upon  the  case. 
This  commission  shall  be  composed  of  three  persons,  of 
whom  one  at  least  shall  be  a  physician  and  another  a 
lawyer.  If  after  hearing  the  evidence  they  think  it  a 
suitable  case  for  confinement,  the  judge  shall  issue  his 


warrant  for  such  disposition  of  the  insane  person  as  the 
circumstances  of  the  case  require.  If  any  insane  person 
is  manifestly  suffering  from  want  oi  proper  care,  any  law 
judge  shall  order  him  to  be  placed  in  some  hospital  for 
the  insane.  In  such  cases,  however,  notices  must  be 
served  and  a  hearing  given." 

There  seems  to  be  a  sufficient  remedy  indicated  in  the 
above. — Ed.] 


Official  List  of  Changts  in  the  Stations  and  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army, 
from  July  20  to  July  26,  1884. 

Wright,  J.  P.,  Major  and  Surgeon.  Granted  leave 
of  absence  for  one  month  on  surgeon's  certificate  of  dis- 
ability. S.  O.  89,  par.  3,  Headquarters  Department  of 
Texas,  July  17,  1884. 

Hartsuff,  Albert,  Major  and  Surgeon.  Leave  of 
absence  extended  one  month.  S.  O.  79,  Headquarters 
Division  of  the  Missouri,  July  18,  1884.  ^ 

Reed,  Walter,  Captain  and  Assistant  Surgeon.  Re- 
lieved from  duty  at  Fort  Sidney,  Neb.,  and  ordered  for 
duty  as  Post  Surgeon,  Fort  Robinson,  Neb.,  relieving 
Assistant  Surgeon  Henry  McEIderry,  U.  S.  A.  S.  O.  62, 
par.  2,  Headquarters  Department  of  Platte,  July  22, 1884. 

Benham,  R.  B.,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  at  Fort  Brown,  Texas.  S.  0. 
90,  par.  I,  Headquarters  Department  of  Texas,  July  19, 
1884. 

Strong,  Norton,  First  Lieutenant  and  Assistant  Sur- 
geon. Granted  leave  of  absence  for  two  months,  to  take 
effect  when  relieved  from  duty  in  Department  of  the 
Platte.  S.  O.  68,  par.  2,  Headquarters  Division  of  the 
Missouri,  June  27,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy,  during  the  week  ending  July  19,  1884. 

GiHON,  A.  L.,  Medical  Director.  Ordered  as  Member 
of  Board  of  Inspection. 

Persons,  R  C,  Passed  Assistant  Surgeon.  Ordered 
to  U.  S.  S.  Saratoga. 

Seigfried,  C.  a..  Passed  Assistant  Surgeon.  Detached 
from  U.  S.  S.  Saratoga;  ordered  to  Naval  Hospital, 
Brooklyn. 

Sayre,  J.  S.,  Assistant  Surgeon.  Ordered  to  U.  S.  S. 
Independence. 


ijacdicaX  %ltms. 


Contagious  Diseases — ^Wsskly  Statkmknt. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  July  19,  1884  : 


Week  Ending 


Casgs, 

July  19, 1884  . . 
July  12,  1884.., 

Deaiks. 
July  19, 1884.  . 
July  12,  1884.. 


I 


167 
187 


I 


Tubercle  Bacilli  in  the  Non-tuberculous. — Dr. 
George  Zahn  records  at  length  a  case  in  which  tubercle 
bacilli  were  found  in  the  sputa,  but  in  which  after  death 
no  tuberculous  process'at  all  was  found  in  the  lungs. 


August  2,  1884.] 


THE   MEDICAL  RECORD. 


139 


Alum  coagulates  the  albumen  of  the  saliva  and  mucus 
of  the  mouth  into  membrane>like  flakes.  It  causes  con- 
traction of  the  capillaries,  blanching  of  the  mucous  mem- 
brane, and  subsequent  diminution  of  secretion.  Not- 
withstanding its  power  to  coagulate  albumen  it  is  absorbed 
into  the  blood,  and  Or61a  found  it  in  the  liver  and  urine. 
Circulating  in  the  blood  it  contracts  the  capillaries,  pre- 
vents the  emigration  of  leucocytes  and  red  corpuscles, 
and  arrests  secretion  and  hemorrhage.  May  it  not  also 
arrest  cell-growth,  and  may  not  this  harmless  and  not  un- 
pleasant remedy  be  tried  against  sarcomas,  and  even  can- 
cers of  internal  organs  which  cannot  be  reached  by  the 
surgeon's  knife  ? 

AcETUM  Opii  is  made  from  opium,  §  v. ;  nutmeg,  §  j . ; 
sugar,  I  viij. ;  dilute  acetic  acid,  O  ij.  This  is  the 
strongest  liquid  preparation  of  op\um,  viz.,  75  grs.  to  |  j. 
or  6J  minims  to  gr.  j.  It  is  nearly  free  from  the  sickening 
smell  of  opium,  and  less  apt  to  nauseate.  The  nutmeg 
helps  to  prevent  nausea  and  there  is  almost  complete 
absence  of  narcotine,  the  most  irritating  ingredient  of 
opium  to  the  stomach ;  in  this  acetate  equals  deodorized 
opium.  Dose  5  to  10  minims.  It  may  also  be  given  in 
aromatic  vinegar,  to  make  it  still  more  pleasant  and 
efficacious. 

Apomorphia  was  discovered  in  1869,  by  Gee.  It 
results  from  the  action  of  hydrochloric  acid  on  morphia, 
which  extracts  one  molecule  of  water.  Codeia  and 
hydrochloric  acid  makes  chlorocodia,  which  splits  into 
chloride  of  methyl  and  apomorphia ;  sulphate  of  morphia 
with  excess  of  sulphuric  acid  makes  sulph-morphia  and 
sulphate  of  apomorphia.  Apomorphia  is  soluble  in 
water,  ether,  benzol,  or  chloroform.  Two  grains  injected 
into  a  dog  causes  vomiting,  and  coursing  around  the 
room  in  a  curiously  persistent  and  methodical  manner. 
Cats  do  the  same,  and  also  turn  summersaults  in  the  air. 
Two  grains  more  caused  epileptiform  convulsions ;  and 
two  more  perfect  relaxation  and  death.  On  man,  one-fifth 
grain  caused  in  twenty  minutes  headache,  dizziness,  op- 
pression, and  qualmishness ;  face  pale,  free  salivation ; 
pulse  infrequent,  small  and  feeble,  and  free  vomiting  in 
ten  to  twenty  minutes.  It  is  a  cerebral  emetic.  Some- 
times there  is  retching,  at  others  free  vomiting  without 
effort  It  is  chiefly  used  h)q)odermically  in  cases  of  great 
emergency  when  it  is  necessary  to  cause  vomiting.  The 
dose  is  one-fiftieth  to  one-tenth  grain.  It  has  been  used  in 
some  disorders  of  coordination,  in  sick  headaches,  dis- 
orders of  the  cerebellum,  and  in  the  early  stages  of  cerebral 
meningitis.  It  is  a  dangerous  remedy,  and  comparatively 
rarely  used,  although  .  the  homoeopathists  advertise  it 
widely  as  a  remedy  against  sea-sickness. 

.^MONii  Phosphas. — Phosphate  of  ammonia  is  made 
from  dilute  phosphoric  acid,  5  xx. ;  aqua  ammon.  fort.,  q.  s. 
It  has  a  cooling,  sharply  saline  taste,  is  insoluble  in 
alcohol,  but  soluble  in  four  parts  of  cold  water.  Dose, 
ten  to  twenty  grains  three  times  a  day  in  water,  or  barley- 
water.  It  is  supposed  to  make  more  soluble  salts  with 
uric  add  than  those  of  soda  and  lime,  and  to  be  usefulin 
gouty  concretions,  gout,  and  rheumatic  gout.  In  uric  acid 
gravel  it  is  more  than  rivalled  by  borax,  the  utility  of 
which  is  very  great.  It  enters  the  urine  from  the  kidneys 
almost  unchanged,  attacks  the  uric  acid,  which  it  decom- 
poses, forming  a  soluble  urate  of  sodium.  Dose  five  to 
thirty  grains. 

AiCMONii  Boras,  or  borate  of  ammonium,  is  made  from 
one  part  of  boracic  acid  in  three  parts  of  warm  ammonia 
fater.  It  has  a  strong  ammoniacal  odor,  and  dissolves 
in  twelve  parts  of  cold  water.  It  is  used  for  urinary  dis- 
orders  with  an  excess  of  acid  or  earthy  phosphates,  and 
in  irritability  of  the  bladder.  It  has  fallen  into  disuse,  but 
is  nearly  as  useful  as  borate  of  sodium.  Dose  ten  to 
twenty  grains  largely  diluted.  It  of  course  is  one  of  the 
remedies  for  lithaemia,  and  has  been  used  in  low  fevers 
in  the  place  of  the  carbonate  of  ammonia,  especially  when 
there  is  ulceration  of  the  bowels. 


Sugar  as  Food. — The  Deuisch-Amerikanische  Apo* 
theker  Zeitung  (December  i,  1883),  gives  a  note  by  Dr. 
Phipson,  on  sugar  as  a  regular  article  of  diet.  Dr.  Phip- 
son  opposes  the  general  prejudice  ajgainst  sugar.  He 
declares  that  he  has,  during  forty  years,  eaten  very  largely 
of  it,  at  least  a  quarter  of  a  pound  daily,  not  counting 
sugar-forming  substances  taken  at  the  same  time.  Dur- 
ing all  this  time  he  has  not  been  under  the  necessity  of 
taking  medicine,  and  has  not  suffered  from  any  com- 
plaint, except  brief  attacks  which  could  be  traced  to 
irregularities  in  eating  or  in  dress.  He  declares  that  the 
condition  of  men  would  be  much  improved  if  the  use  of 
sugar  should  substitute  that  of  alcohol. 

An  Antirachitic  Mixture. — Dr.  Von  Leser  rec- 
ommended, in  a  paper  read  before  the  Leipzig  Medical 
Society,  the  following  mixture  in  the  treatment  of 
rachitis : 

51.  Tinct.  rhei  vinos 20  parts. 

Solut.  potas.  acetici 10      ** 

Vini  stibiati 5      " 

M. 
The  beginning  dose  is  five  to  ten  drops  three  times 
daily.  This  is  increased  three  drops  every  three  days 
until  twenty  to  thirty  drops  is  reached.  The  maximum 
dose  is  continued  three  or  four  weeks.  Improvement 
sets  in  so  rapidly  that  this  is  then  rapidly  decreased- 

The  Cause  of  Objective  Quacking  Sounds  in  the 
Ear. — Dr.  William  S.  Parker,  of  Piqua,  O.,  recounts  the 

following  case  and  asks  for  a  diagnosis  :  "  Miss  D , 

aged  thirty,  about  the  last  of  October,  1883,  ^^.d  a  slight 
fainting  spell,  not  amounting  to  unconsciousness,  accom- 
panied with  nausea  and  thickness  of  speech,  so  much 
so  that  she  was  unable  to  articulate.  This  lasted  but 
an  hour  and  a  half,  and  was  the  only  attack  she  ever 
had.  I  may  mention  that  for  several  years  she  has 
been  subject  to  very  slight  attacks  of  vertigo,  which,  but 
for  the  present  state  of  affairs,  would  pass  unnoticed. 
Since  the  attack  in  October  she  had  constant  ringing  in 
the  ears  until  January  i,  1884,  at  which  time  she  noticed 
that  the  sound  became  interrupted  in  a  manner  hereafter 
described.  I  observe  that  she  is  in  perfect  health  in  every 
particular,  and  never  had  any  serious  illness.  The  ears 
are  perfect,  as  is  also  their  function.  Upon  examination 
at  this  date  (June  12,  1884),  I  find  by  placing  my  ear 
against  that  of  the  patient,  a  distinct  sound,  precisely  like 
that  of  the  quacking  of  a  mallard  duck  in  the  far-off  dis- 
tance (which  she  says  exactly  describes  the  sound  as  it 
seems  to  her).  This  sound  is  synchronous  with  each  beat 
of  the  heart,  and  is  heard  very  distinctly  in  the  left  ear, 
and  only  slightly  less  so  in  the  right  by  myself,  although 
the  patient  can  only  perceive  it  in  the  left  ear.  Press- 
ure upon  the  carotids  makes  no  difference  in  the  sound. 
Inflition  of  the  Eustachian  tube  also  has  no  effect.  Ly- 
ing upon  the  left  ear  intensifies  the  sound  very  largely, 
says  *  it  is  like  the  roaring  of  a  saw-mill.'  This  condi- 
tion has  obtained  since  January  ist  last,  when  it  was  first 
observed." 

Removal  of  Benign  Mammary  Tumors  without 
Mutilation. — Dr.  N.  E.  Oliver,  of  Thornton,  111., 
sends  us  the  following :  **  In  yoiu:  issue  of  July  5  th  (Vol. 
xxvi.,  No.  i),  on  page  12,  is  an  excerpt  from  TTie  Ar- 
chives Med,  BelgeSy  in  which  M.  Moli^re  claims  origi- 
nality for  the  (therein  described)  operation  for  the  re- 
moval of  (benign)  mammary  tumors  without  mutilation. 
Professor  T.  Gaillard  Thomas,  in  a  communication  (read 
before  the  New  York  Obstetrical  Society,  February  21, 
1882)  to  The  New  York  Medical  Journal  and  Obstetrical 
Review  for  April,  1882,  describes  the  above  operation  as 
applicable  to  all  benign  tumors  of  medium  size.  It  would 
seem  that  American  medical  literature  scarcely  receives 
appropriate  recognition  from  our  irascible  French  breth- 
ren, otherwise  so  distinguished  a  gentleman  would  not  be 
guilty  of  so  palpable  a  *  medical  plagiarism,'  or  at  any 
rate  he  would  not  be  two  years  behind  the  times." 


I40 


THE  MEDICAL  RECORD, 


[August  2,  1884. 


Trichinosis  in  Massachusetts. — Dr.  Averill,  of 
Campello,  Mass.,  sends  us  the  notes  of  several  cases  of 
trichinosis  recently  occurring  in  his  practice.  He  writes : 
"On  March  27,  1884,  I  was  asked  to  visit  a  Swedish 
family  consisting  of  husband,  wife,  and  four  children.  I 
found  husband  and  wife  and  eldest  child  (a  son  about 
eight  eight  years  of  age)  all  sick  in  bed,  and  learned 
that  they  all  took  to  their  beds  about  the  same  time 
some  three  or  four  days  before  calling  for  me.  All  had 
felt  tired  and  languid  for  several  days  before  taking  to 
the  bed.  All  were  cedematous  about  the  face  and  eyes, 
and  the  wife  was  markedly  so  all  over  her  body.  They 
complained  of  pains  all  through  their  bodies,  headache, 
lassitude,  muscles  were  sore  and  painful  when  touched 
or  moved,  limbs  generally  flexed,  and  extension  caused 
extreme  pain.  The  husband  complained  especially  of 
pains  across  his  thorax.  Temperature  about  102^°,  pulse 
about  125."  Dr.  Averill  learned  that  about  a  week  be- 
fore the  sickness  the  family  bought  half  a  smoked  ham, 
and  all  had  been  eating  it  raw  except  the  three  younger 
children,  who  ^^ere  not  attacked.  Another  family  in  the 
same  house  bought  the  other  half  of  the  ham.  The  hus- 
band alone  ate  some  of  it  raw,  and  he  alone  was  taken 
sick,  but  recovered.  The  three  sick  members  of  the 
first  family  gradually  recovered,  but  it  was  about  five 
weeks  before  the  symptoms  had  disappeared. 

The  Lack  of  Progress  of  Cremation. — With  refer- 
ence to  our  recent  editorial  upon  this  subject,  Dr.  F. 
Hoffmann,  editor  of  the  Pharmac cutis che  Rundschau^ 
calls  our  attention  to  an  article  by  himself  in  the  March 
number  of  that  journal.  He  there  shows  by  statistics 
the  very  slight  progress  that  cremation  as  a  mode  of 
burial  is  making,  and  takes  the  ground  that  it  is  an  un- 
called-for and  dangerous  mortuary  rite. 

The  Psvcho-pathologv  of  an  Application  for  In- 
crease OF  Pension. — A  pension  surgeon  at  Washington 
sends  us  the  copy  of  a  very  ingenious  medical  certificate 
which  was  sent  to  his  office  a  few  days  ago  with  an  ap- 
plication for  an  increase  of  pension.  "  Affiants  discover 
upon  the  right  instep  of  the  applicant  a  soft  and  mova« 
ble  cicatrix,  as  if  the  integuments  had  been  ploughed  up 
by  a  bullet.  We  find  no  deformity  or  displacement  of 
the  tarsal  or  metatarsal  bones,  and  no  erythema  or  hy- 
peraesthesia  of  the  surface  of  the  wounded  region.  Affi- 
ants also  discover  that  the  applicant's  disability  is  greatly 
increased  at  times  by  the  reaction  of  the  above  described 
cicatrix  on  the  higher  nervous  centres.  We  believe  that 
a  sensory  impression,  conveyed  from  the  cicatrix  through 
the  second  pair  of  cranial  nerves,  is  intensified  in  the 
cerebrum  by  certain  processes  of  intellection,  one  of 
which  is  known  as  expectant  attention.  The  impression 
so  intensified  and  modified  is  then  refiected  to  the  region 
where  the  trauma  was  sustained,  and  the  applicant's  suf- 
ferings are  increased  many  fold.  Under  such  circum- 
stances, and  at  the  time  when  these  reflex  nervous  phe- 
nomena are  manifested,  we  believe  that  the  applicant's 
disability  is   extreme,  and  that  an  increase  is  urgently 

indicated  as  a  therapeutic  measure.     ,  M.D., ^ 

M.D." 

The  Therapeutic  Value  of  the  Iron  Albumi- 
nate in  ANiEMiA. — Dr.  Allan  McLane  Hamilton  writes : 
"  I  have  been  in  the  habit  for  several  years  past  of  giving 
iron  in  combination  with  albumen  to  nervous  patients 
whose  powers  of  assimilation  were  so  enfeebled  that  they 
were  unable  to  take  any  of  the  preparations  in  ordinary 
use,  even  the  most  bland  and  non-irritating.  Anaemic 
and  hysterical  women  and  those  with  idiosyncrasies  often 
declare  their  unwillingness  or  inability  to  continue  the 
iron,  even  in  minute  doses,  and  in  such  patients  something 
must  be  found  to  take  its  place.  In  the  year  187 1  Diehl 
announced  the  discovery  of  the  albuminate  of  iron,  but 
so  far  as  I  can  discover,  no  one  has  yet  employed  the 
combination  in  medicine.  Miahle  has  held  that  'the 
albuminate  of  the  peroxide  of  iron  is  formed  in  the  blood 
and  that  this  is  the  basis  of  the  red  globules,'  and  it  has 


been  shown  that  the  presence  of  an  alkali  favois  the 
catalytic  change.  Some  iron  salts  are  absolutely  inert  as 
remedies  and  pass  unaltered  from  the  body.  Among 
these  are  the  ferro  and  ferricyanides  of  potassium  and 
other  double  salts  which  are  not  precipitated  by  the  alka- 
lies (Headland).  The  combination  of  iron  and  albumen 
with  an  alkali  seems  to  be  at  once  a  measure  likely  to 
be  of  value  from  a  therapeutic  point  of  view,  and  so  1 
have  found  it.  Mr.  Theodore  Angelo,  of  New  York,  has 
made  for  me  a  dry  preparation  of  the  iron  albuminate,  and 
he  has  combined  with  this  chocolate  and  moulded  this 
into  small  lozenges,  each  of  which  contains  ten  grains  of 
the  salt.  I  have  given  the  iron  albuminate  a  thorough 
trial  in  a  large  number  of  cases  of  all  kinds  where  a 
haematic  was  needed,  and  am  convinced  that  there  is  no 
form  of  iron  now  in  use  that  acts  as  rapidly  or  is  so 
well  borne  by  the  stomach  as  that  of  which  I  write." 

A  Question  of  Maternal  Impression. — Dr.  C.  H. 
French,  of  Waterbury,  Conn.,  writes :  "  I  was  engaged  to 

attend  Mrs.  T during  her  confinement.     Soon  after 

conception  a  young  man,  whose  right  arm  just  above 
the  elbow  had  been  amputated  some  years  ago,  came  to 

board  in  the  family.     Mrs.  T felt  very  sorry  for  the 

young  man,  showing  her  sympathy  by  frequently  washing 
and  dressing  the  arm.  She  says  that  that  young  man's 
arm  was  seldom  out  of  her  mind,  and  that  any  person 
she  saw  who  was  similarly  affected  (she  had  seen  several) 
sent  a  thrill  of  horror,  followed  by  one  of  intense  sympathy, 
through  her.  I  delivered  her,  on  June  5  th,  of  twins. 
One  of  the  children  had  the  right  arm  just  below  the 
elbow  missing.  Whether  this  was  merely  a  coincidence 
or  the  result  of  the  mother's  mind  over  the  foetal  devel- 
opment I  am  not  prepared  to  state.  In  view  of  the  fact 
that  cases  of  this  nature,  taken  collectively,  may  be  of 
value,  I  send  you  this.** 

Some  Delusions  in  Medical  Chemistry. — That 
colorless  tincture  of  iodine  has  the  chemical  and  medical 
properties  of  the  tincture  of  iodine.  That  serum  albumen 
is  the  only  albuminous  body  to  be  tested  for  in  the  urine. 
That  potassium  chlorate  yields  oxygen  to  the  blood 
(some  recent  experiments  have  made  this  not  so  improb- 
able). That  corrosive  sublimate  or  potassium  perman- 
ganate can  be  given  with  vegetable  preparations. 

Identity  of  Friedlander's  Pneumonia  Cocci  with 
THE  Organisms  of  Salivary  SEPTiCiEMiA. — Dr.  George 
M.  Sternberg,  U.  S.  A.,  sends  us  the  following  important 
communication  :  "  I  am  induced  by  yoiu"  remarks  upon 
*  Micrococci  under  the  Floor '  (The  Medical  Record, 
June  28),  to  call  your  attention  to  the  apparent  morpho- 
logical identity  of  Friedlander's  micrococci  of  pneumonia 
and  the  micrococci  from  the  blood  of  a  rabbit  inoculated 
with  human  saliva,  shown  in  Fig.  i  of  the  plate  which 
illustrates  my  paper  on  *  A  Fatal  Form  of  Septicaemia  in 
the  Rabbit,*  etc.  (published  in  1881),  a  copy  of  which  I 
send  you  by  mail  to-day.  This  morphological  identity 
was  recognized  at  once  by  Dr.  Wm,  Welch,  of  New 
York,  when  I  called  his  attention  to  this  figure,  upon  his 
visiting  the  biological  laboratory  at  Johns  Hopkins  Uni- 
versity not  long  since.  As  Dr.  Welch  has  personally 
demonstrated  the  presence  of  Friedlander's  (?)  micrococ- 
cus in  pneumonic  sputum,  his  recognition  of  this  mor- 
phological identity  at  once  confirmed  my  own  suspicions. 
I  have  not  myself  had  an  opportunity  to  examine  pneu- 
monic sputum  since  the  announcement  of  Friedlander's 
discovery  (?)." 

Urinary  Test  Papers. — Messrs.  Parke  Davis  &  Co., 
of  Detroit,  have  manufactured  a  very  neat  and  con- 
venient pocket  case  containing  the  various  test  papers 
for  urinary  analysis  recommended  by  Dr.  G.  Oliver,  of 
Harrowgate,  Eng.  {Lancety  February  3,  1884),  and  Dr. 
C.  W.  Purdy,  of  Chicago  {Jour.  Amer.  Med.  Assoc.^ 
January  19,  1884).  It  is  also  supplied  with  test  tubes, 
and  dropper  making  the  whole  a  very  useful  pocket 
companion  for  the  general  practitioner. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  6 


New  York,  August  9,  1884 


Whole  No.  718 


(^viQimd  ^tMcUs. 


PUERPERAL  FEVER, 

Being  an  Address  on  Obstetric  Medicine, 

Delivered  at  the  Fifty^second  Annual  Meeting  of  the 
British  Medical  Association,  held  in  Belfast,  1884, 

By  GEORGE  H.    KIDD,  M.D.  Ed.  ;   M.A.O.,  Hon.  Causa, 
Duel. 

nUOV  AND  KX-PnSlDKNT  ROYAL  COLLBGK  OP  8URGBOM8,  ISKLAND ;  HONOHARY 
mXOW  LONDON  AND  BUNBURGH  OBSTBTSICAL  SOCIBTIBS  ;  CORRRSPOND- 
nC  MIMBBR  OP  THE  GYNRCOLOGICAL  SOCIXTIBS  OP  BBRUN  AND  BOSTON  ; 
OORSPLTART    AND    BX-MASTSR    OP  IHB    COOMBS    LYING-IN   HOSPITAL.*   CON- 

scLTUfC  oBsrrrRic  surgbon  to  thb  hospitals  op  the  housb  op  in- 

DOSTKV;    PRBSIOBNT    OP  THB    OBSTBTRIC  5BCTION    OP  THB  IRISH    ACADSIIY 
or  XBDICINB. 

(Special  for  THb  Mbdical  Rbcorix) 

xUsETiNGS  such  as  those  of  the  great  Association  under 
whose  auspices  we  are  here  assembled  have  always  ap- 
I)eared  to  me  as  having  their  most  useful  function  in 
presenting  opportunities  for  reviewing  the  work  we  have 
bees  doing ;  estimating  the  value  of  the  results  attained ; 
elimioating,  so  far  as  may  be,  the  erroneous  or  defec- 
tive; and  so  getting  plainly  before  us  certain  stand- 
points from  which  further  advances  may  be  made.  I 
propose,  then,  in  endeavoring  to  accomplish  the  duty 
imposed  on  me  by  your  Council  when  they  selected 
me  for  the  high  and  honorable  office  of  delivering  an 
address  on  obstetric  medicine,  to  take  Puerperal  Fever 
as  my  subject,  and  to  treat  it  in  accordance  with  these 
piinciples.  In  selecting  this  subject  I  have  been  in- 
flaenced  not  only  by  its  importance — its  vital  importance 
-to  one  and  all  of  us,  but  also  by  the  great  advances 
that  have  recently  been  made  in  our  knowledge  of  its 
pathology,  and  in  some  measure  perhaps  by  the  feeling 
that  in  our  enthusiastic  pursuit  of  the  new  paths  that 
have  been  opened  to  us  we  are  in  danger  of  losing  the 
due  that  is  to  lead  us  out  of  the  labyrmth  in  which  we 
have  so  long  been  wandering.  I  shaJl  ask  you  to  con- 
ader  the  disease  mainly  from  a  clinical  point  of  view, 
refemng  to  the  laboratory  experiments  of  scientists  and 
pathologists  to  illustrate  and  explain  the  facts  observed 
at  the  bedside,  where  alone  disease  can  be  studied.  In 
(kang  this  I  shall  not  attempt  to  present  any  new  or 
ongina]  doctrines.  My  task  must  be  the  more  humble 
one  of  stating,  with  what  clearness  I  may,  the  questions 
at  issue,  and  the  facts  on  which  their  solution  must  be 
founded,  endeavoring  to  arrange  and  balance  the  evi- 
dence, so  that  its  true  value  may  be  more  fully  appre- 
hended. 

Much  of  the  difficulty  that  has  always  attended  the 
study  of  this  disease  arises  from  the  similarity  of  the 
symptoms  during  life  and  of  the  pathological  appearances 
^Dond  after  death  in  its  various  forms.  Its  dependence 
on  the  great  act  of  childbirth,  and  the  peculiar  condition 
of  the  patient's  system  at  this  period,  sufficiently  account 
for  this  similarity.  The  enlarged  and  highly  organized 
uterus  suddenly  emptied  of  its  contents  after  violent 
muscular  exertion,  and  becoming  a  mass  of  efifete  mate« 
lial,  whose  constituent  elements  have  to  be  absorbed 
into  the  blood  as  a  preliminary  to  their  being  eliminated 
from  the  system  ;  the  exposed  state  of  its  vessels ;  the 
torn  and  contused  tissues ;  the  great  current  of  blood 
Verted  from  the  course  it  has  so  long  been  pursuing  ; 
the  altered  condition  of  the  fluid  itself;  and  the  highly 
stnmed  nerve-tension — all  tend  to  concentrate  the  dis- 


eased action  of  one  set  of  organs,  and  to  impress  on  it 
this  similarity  of  development  The  attempts,  conse- 
quently, that  have  from  the  earliest  times  been  made  to 
differentiate  the  various  forms  of  the  disease,  founded  on 
its  morbid  anatomy  and  its  symptoms,  have  failed  to 
simplify  its  study  or  in  any  great  degree  elucidate  its  na^ 
ture.  A  classification  founded  on  the  conditions  under 
which  the  disease  arises,  and  the  nature  of  the  exciting 
cause  adopted  by  some  writers,  as  by  Barnes  in  modem 
times,  has  proved  more  useful  and  done  more  to  pro- 
mote accuracy.  One  founded  on  this  principle  will 
probably  best  serve  the  requirements  of  the  present 
occasion. 

A  writer  of  the  last  century,  Kirkland,  upbraids  his 
contemporaries  with  including  ^'  a  thousand  disorders  '* 
under  the  one  head  of  puerperal  fever.  It  requires  but 
a  very  elementary  knowledge  of  the  subject  to  see  that 
a  large  proportion  of  these  disorders  arise  from  traumatic 
causes.  These,  then,  will  constitute  the  first  group  I 
will  ask  you  to  consider,  and  perhaps  not  the  least  im- 
portant, seeing  that  so  much  can  be  done  for  their  pre- 
vention. 

In  tedious  and  difficult  labors,  more  especially  in  first 
labors,  the  soft  parts  of  the  mother  are  liable  to  be  in- 
jured at  every  stage — the  cervix  may  be  lacerated,  the 
lips  may  be  caught  between  the  head  of  the  child  and 
the  side  of  the  pelvis  and  contused,  the  vaginal  walls 
may  be  compressed  till  sloughing  be  induced,  so  as  to 
lay  open  the  bladder  or  the  rectum,  or  both ;  the 
perineum  may  be  torn,  or  some  of  the  blood-vessels  may 
be  lacerated,  and  blood  be  effused  into  all  the  surround- 
ing tissues,  giving  rise  to  hematoceles,  more  or  less  ex- 
tensive ;  and  yet,  formidable  as  the  enumeration  seems, 
we  all  know  that  in  the  great  majority  of  cases  the  reac- 
tion is  moderate,  the  inflammation  set  up  is  localized,  if 
the  damage  done  be  not  excessive  it  is  repaired,  and  the 
patient  recovers.  But  if  the  patient  be  in  an  unhealthy 
condition,  or  if  her  surroundings  be  unwholesome,  then 
a  new  train  of  symptoms  may  arise,  not  necessarily  de- 
'^nding  on  the  extent  or  gravity  of  the  wounds,  but 
influenced  by  them.  The  inflammation,  instead  of  being 
normal  in  character,  becomes  abnormal ;  it  may  extend 
to  surrounding  parts,  and  peritonitis  or  pelvic  cellulitis 
may  be  set  up ;  or  more  distant  parts  may  be  affected, 
and  the  disease  will  manifest  itself  in  the  pleura  or  the 
serous  membranes  of  the  heart  or  of  the  joints  ;  or  the 
blood  in  the  veins  may  be  coagulated,  giving  rise  to 
thrombi  and  emboli,  and  subsequently  pyaemia. 

We  have  now  to  inquire  what  is  the  nature  of  this 
change.  The  researches  of  modem  pathologists  and 
scientists  have  proved  that  it  is  due  to  the  introduction 
of  a  poison  into  the  system,  and  that  certain  vegetable 
organisms  (bacteria)  are  essential  agents  in  the  produc- 
tion and  dissemination  of  this  poison.  They  are^not 
agreed,  however,  as  to  the  exact  part  played  by  these 
organisms.  Some  hold  that  the  most  severe  injuries  may 
be  inflicted  without  producing  inflammation,  and  that 
when  inflammation  takes  its  origin  from  a  wound,  all  that 
the  wound  does  is  to  play  the  part  of  the  door  of  en- 
trance for  the  real  noxa — ^water  germ,  air  germ,  or  germ 
which  sticks  to  the  surface  of  the  weapon  or  missile  which 
inflicts  the  injury.  They  assert  that  in  the  genesis  of 
every  inflammation,  however  definite  may  be  the  relation 
between  the  antecedent  damage  and  consequent  reaction, 
this  relation  is  after  all  merely  secondary.  The  tme 
cause  is  the  introduction  into  the  damaged  tissue  from 


142 


THE  MEDICAL  RECORD- 


[August  9,  1884. 


the  atmosphere  of  invisible  germs.  Where  there  are  no 
germs,  there  is  no  possibility  of  inflammation.  Others, 
as  Dr.  J.  Burdon-Sanderson,  to  whom  we  are  indebted 
for  most  of  our  exact  knowledge  on  the  subject,  teach 
that  inflammation  is  the  direct  physiological  effect  of  in- 
jury, and  that  the  only  inflammations  to  which  minute 
organisms  stand  in  relation  are  those  which  from  their 
proved  dependence  on  previously  existing  inflammation 
may  properly  be  termed  secondary  or  infective,  and  that 
consequently  the  organisms  in  question  were  in  all  prob- 
ability not  so  much  mischief-makers  as  mischief-spreaders 
— that  is  to  say,  although  an  inflammation  may  come 
into  existence  without  their  aid,  their  presence  communi- 
cates to  it,  after  it  has  come  into  existence,  the  power 
of  reproducing  itself  in  previously  healthy  tissues,  whether 
by  extension  or  dissemination.  During  the  ten  years 
which  have  elapsed  since  1872  (when  he  first  taught  this), 
Dr.  Sanderson  says  the  question  of  the  intervention  of 
micrococci,  which  was  then  strange  even  to  professed 
pathologists,  has  become  familiar  to  everyone,  and  now 
the  tendency  exists  to  believe  that  germs  explain  everyn 
thing ;  so  that  whereas  formerly  one  had  to  vindicate 
the  very  existence  of  such  things  as  parts  of  pathological 
processes,  it  has  now  become  a  part  of  one's  business  to 
protest  with  all  needful  vehemence-  against  the  attribu- 
tion to  them  of  functions  they  do  not  possess.* 

In  support  of  his  theory  he  proves  a  series  of  proposi- 
tions on  an  experimental  basis  that  seem  to  leave  no 
room  for  rational  doubt.  He  shows  that  the  introduction 
into  the  circulating  blood  of  a  relatively  large  quantity 
of  exudation,  which  is  the  most  important  effect  of  a  con- 
siderable local  inflammation,  does  not  produce  second- 
ary inflammation  elsewhere,  and  is  not  attended  with 
any  serious  constitutional  disturbance.  He  further  shows 
that  no  organisms  endowed  with  inflammation-producing 
phlogogenic  particles  exist  in  the  atmosphere  or  in  the 
ordinary  aqueous  liquids  with  which  our  bodies  come 
into  contact. 

It  had  been  proved  by  Hiller  that  bacteria  collected 
from  fluids  in  an  advanced  state  of  putrefaction  might, 
when  washed  and  purifled,  be  introduced  into  the  circu- 
lating blood  without  producing  any  injurious  efi'ect, 
though  proved  to  be  as  lively  and  capable  of  develop- 
ment as  ever.  Hiller*  even  inoculated  himself  with 
them.  Dr.  Wegner*  showed  that  the  subcutaneous  tissue 
of  a  rabbit  may  be  kept  distended  for  days  by  frequently 
renewed  injections  of  unpurified  air  without  producing 
inflammation,  and  that  the  effect  was  not  more  serious 
if  the  same  tissue  were  ventilated  for  a  number  of  hours 
by  a  continuous  current  of  air,  even  when  that  air  was 
derived  from  a  post-mortem  theatre.  When  water  charged 
with  septic  bacteria  was  injected  into  the  peritoneum  of 
a  rabbit,  in  quantity  less  than  two  ounces,  it  produced 
no  effect  whatever.  When  the  animal  was  killed,  the 
fluid  had  been  absorbed  and  the  lymphatics  of  the 
diaphragm  were  full  of  bacteria,  but  neither  in  them  nor 
in  the  peritoneum  were  there  any  signs  of  inflammation. 
Similarly  it  was  found,  that  when  a  current  of  the  fluid 
was  passed  through  the  peritoneum  for  many  hours,  so 
that  the  membrane  was  exposed  for  a  long  time  to  what- 
ever phlogogenic  influences  the  liquid  conveyed,  no 
effect  whatever  was  produced.  These  experiments  with 
watery  liquids  are  even  more  conclusive  than  those  with 
air,  for  we  have  here  to  deal  with  media,  in  every  particle 
of  which  we  can  very  readily  prove  the  actual  existence 
of  germs  in  such  a  state  of  viability  as  to  only  require  a 
suitable  soil  to  insure  their  development. 

Having  thus  proved  that  the  exudation  of  a  normal 
inflammation  is  not  infective,  and  that  no  organisms 
endowed  with  inflammation-producing  phlogogenic  par- 
ticles exist  in  the  atmosphere  or  in  the  ordinary  aqueous 
liquids  with  which  our  bodies  come  into  contact,  Dr. 

ilLiunldAn  Lectures  on  Inflammadoa.  Deiivored  before  the  Royal  College  of 
Physicuuis.  By  J.  Burdon-Sanderaon,  M.D.,  etc.  Brit.  Med.  Journal,  Aiml  8, 
x88a,  p.  40J. 

>  Brit.  Med.  Jour.,  January  5,  1878,  p.  a.       *  Ibid.,  April  15,  x88s,  p.  597. 


Sanderson  proceeds  to  show  that  whenever  an  inflamma- 
tion becomes  infective  it  owes  that  property  to  a  chemi- 
cal change  in  the  exudation  liquid,  of  which  the  presence 
of  microzymes  is  a  necessary  condition,  and  that  con. 
versely  septic  organisms,  which  are  infectious,  owe  their 
infectiveness  to  the  exudation  soil  in  which  they  have 
grown.      He  refers   to  experiments  he  made  a  dozen 
years  ago,  which  showed  that  in  rodent  animals  peri- 
tonitis  induced   by  the   injection   of  irritant  liquids  is 
always  infective,  notwithstanding  that  the  irritant  (tinc- 
ture of  iodine)  was  not  only  free  from  germs,  but  de- 
structive of  them.      This  was,  he   says,  understood  to 
mean  that  the  flrst  effect  of  the  iodine  was  the  effusion 
of  liquid  into  the  peritoneal  cavity  ;  the  second  the  in- 
fection of  this  liquid  by  formed  ferments  which  found 
their  way  into  it,  not  from  the  atmosphere  or  from  ex- 
ternal media  of  any  kind,  but  from  the  alimentary  canal. 
In  another  experiment,  water  which  had  been  boiled  so 
as  to  remove  all  germs  that  might  have  been  in  it,  was, 
when  cool,  injected,  with  antiseptic  precautions,  in  so 
large  a  quantity  that  it  could  not  be  rapidly  absorbed. 
When  thus  accumulated  in  the  serous  cavity  it  charged 
itself  by  diffusion,  first  with  the  salts,  subsequently  in 
increasing  proportion  with  the  proteids  of  the  blood,  and 
thus  became  a  most  favorable  soil  for  the  development 
of  septic  organisms,  whicli  in  their  turn  acted  infectively 
or  phlogogenically  on  the  blood-vessels  and  living  tissues 
with  which  they  came  in  contact.     A  septic  peritonitis 
ensued,  which  killed  the  animal  by  septicemia  in  twenty- 
four  or  thirty-six  hours.     It  is  thus  shown  that  though 
the  seed  is  indispensable  to  the  coming  into  existence 
of  the  infective  process,  the  question  whether  that  seed 
becomes  morbific  or  not  depends  not  on  the  seed  itself, 
but  on  the  soil.      Other  experiments  prove  the  same 
thing,  and  the  whole  result  is  to  establish  that  the  pres- 
ence of  septic  organisms  (provided  that  they  have  not 
been  bred  inside  the  organism)  is  not  necessarily  at- 
tended with  any  danger,  but  that  they  become  sources 
of  danger  at  once  when  they  are  brought  into  relation 
either  with  devitalized  organs  or  with  extravasated  serous 
fluids  of  any  kind,  and  particularly  with  inflammatory 
exudation. 

The  sum  of  our  knowledge  of  these  organisms  seems 
to  be  this  :  They  are  found  everywhere — in  the  air,  in 
water,  in  the  soil ;  in  the  bodies  of  the  most  healthy  ani- 
mals, on  the  surface  where  most  exposed  to  the  air ;  in 
the  entrances  to  the  alimentary  and  air  passages  ;  in  the 
stomach  and  upper  portions  of  the  alimentary  canal,  but 
not  frequently  here,  for  acid  secretions  kill  them ;  in  the 
lower  portions  of  the  canal  frequently ;  possibly  also  in 
the  tissues  of  solid  organs,  as  in  the  pancreas,  liver,  kid- 
ney, muscle,  but  this  is  still  a  disputed  question.  In  the 
circulating  blood  of  healthy  animals  they  are  never  found. 
They  enter  the  system  by  the  absorbents  of  the  mucous 
membrane  of  the  small  intestines,  the  lacteals,  by  the 
pulmonary  mucous  membrane,  by  recent  wounds,  by  the 
uterine  surface  after  delivery.  They  exist  in  the  animal 
body  without  interfering  with  health.  If  they  meet  with 
a  proper  soil,  such  as  exudation  liquid,  or  dead  tissue, 
they  set  up  putrefaction,  and  in  the  process  of  putrefac- 
tion a  poison  is  produced  which,  mingling  with  the  blood, 
poisons  it  and  gives  rise  to  septicaemia.  This  poison  they 
carry  into  the  system,  but  the  bacteria  themselves  are 
not  poisonous. 

Thus,  then,  we  must  have  two  factors  for  the  produc- 
tion of  the  poison — (i)  The  material  capable  of  putre- 
faction ;  and  (2)  bacteria  to  effect  putrefaction. 

Now,  how  are  we  to  apply  this  to  our  subject  ?  It  is 
well  known,  as  Billroth  remarks,  that  in  most  open 
wounds,  especially  in  contused  wounds,  shreds  of  con- 
nective tissue  die,  and  in  many  spontaneous  inflamma- 
tions the  circulation  ceases  in  some  parts  of  the  Inflamed 
tissues  and  they  die.  Here,  then,  we  have  the  material 
from  which  the  poison  is  to  be  elaborated,  and  the  infer- 
ence is  plain  that  the  first  step  to  be  taken  to  avoid  this 
form  of  puerperal  fever  is  to  so  conduct  the  labor  as  to 


August  9,  1 884,] 


THE  MEDICAL  RECORD. 


143 


lessen  the  amount  of  injury  done,  to  be  careful  that  the 
membranes  be  not  ruptured  too  soon,  and  that  the  head 
be  not  allowed  to  press  so  long  on  the  soft  parts  as  to 
injure  them,  and  above  all  that  no  violence  be  used. 

In  the  second  place,  to  cut  off  so  far  as  possible  the 
access  of  bacteria  to  the  injured  parts,  by  cleanliness,  by 
yentilation,  by  disinfection ;    but   the    experiments  of 
Cbanveau  and  of  Kocher,  of  Berne  and  of  Sanderson, 
prove  that  even  where  all  access  of  orp;anisms  from  with- 
out is  cut  off  they  will  pass  from  the  mtestinal  canal  or 
other  sources  to  the  point  where  dead  or  dying  tissue 
exists,  and  there  set  up  putrefaction  and  the  elaboration 
of  the  septic  poison,  and  consequently  a  third  indication 
remains  of  equal,  if  not  greater,  importance   than  the 
others — that  is,  to  remove  the  products  of  decomposition 
as  quickly  as  possible.     Cleanliness,  the  adage  says,  is 
next  to  godliness.     Mr.  Simon  has  modified  this,  and 
tells  us  that  of  all  our  present  removable  causes  of  dis- 
ease uncleanliness  is  the   most  deadly;  and  Burdon- 
Sanderson  tells  us  that  the  only  scientific  definition  of 
filth  is  that  it  consists  of  the  products  of  bacterial  evolu- 
tion.   If  the  septic  poison  be  not  introduced  too  quickly, 
too  frequently,  or  in  too  large  a  quantity,  the  living 
blood  and  tissues  will  decompose  and  neutralize  it     They 
are  the  best   colytics.     All   collections   of    blood   and 
liquids  must  be  prevented.     Liston  did  this  by  leaving 
the  wounds  after  his  operations  exposed  to  the  air  for  five 
or  six  hours,  or  covered  with  lint  dipped  in  water  till  all 
oozing  had  ceased  and  the  surfaces  were  glazed  over,  and 
then  brought  them  into  apposition.     This  was  before  the 
days  of  antiseptic  surgery,  yet  the   wounds  were   not 
poisoned  by  atmospheric  germs.     Lister  leaves  drainage- 
tabes  in  the  wound  to  carry  off  the  fluids  as  formed.     In 
obstetric  practice  we  must  depend  on  the  natural  drainage 
and  on  frequent  washings  by  the  syringe.     Billroth  says 
that  in  ordinary  wounds  the  secretion  poured  out  within 
the  first  forty-eight  hours  is  especially  active,  and  that 
the  stinking  products  of  tissue  decomposition  are  possibly 
the  least  noxious.     This  does  not  seem  to  me  to  hold 
good  of  the  discharges  after  delivery,  but  let  it  be  so  or 
not  we  must  ever  bear  in  mind  that  uncleanliness  must 
be  reckoned  as  the  deadliest  of  our  present  removable 
auses  of  disease. 

The  next  group  we  have  to  consider  is  so  closely  con- 
nected with  the  former  that  it  will  not  be  necessary  to 
direll  on  it  at  any  length.  Since  the  days  of  Hippocrates 
it  has  been  known  that  portions  of  the  placenta,  or  mem- 
branes, or  clots,  retained  within  the  uterus  will  cause 
fever.  As  in  the  laboratory,  infusions  made  of  fragments 
of  organic  matter,  animal  or  vegetable,  afford  the  material 
on  which  bacteria  may  work  and  elaborate  septic  poison, 
so  will  organic  substances  retained  in  the  uterus  afford 
the  conditions  for  the  formation  of  septic  poison,  which, 
when  it  gets  into  the  system,  will  set  up  fever.  Harvey, 
of  whom  it  has  been  said  that  if  he  had  not  been  a  great 
phjsiolc^st,  he  would  have  been  a  .great  obstetrician, 
washed  out  the  uterus  under  these  circumstances  ;  but  it 
is  to  Dr.  Braxton  Hicks  we  are  indebted  for  formally 
recommending  the  practice.  The  rapidity  with  which 
die  fever  subsides  when  this  is  sufficiently  done  proves 
that  the  fever  depends  on  the  absorption  of  the  poison. 

Closely  connected  with  these  groups  is  another  set  of 
cases  where  the  disease  takes  its  origin  in  varicose  veins, 
which  inflame,  and  in  which  thrombi  form,  giving  rise  to 
emboli  and  pyaemia  with  metastatic  abscesses.  Bacteria 
make  their  way  into  these  thrombi,  from  within  the 
system,  and  cause  them  to  disinte^ate  and  break  into 
fragments,  which,  being  carried  off  iri  the  current  of  the 
blood,  get  arrested  at  certain  points  and  give  rise  to 
secondary  inflammations  and  metastatic  abscesses. 

The  foregoing  groups  belong  to  the  class  Dr.  Barnes  ^ 
calls  autogenetic.     Autogenetic  they  are  so  far  as  the  * 
primary  factor  for  their  production  is  concerned,  but  for 
their  development  they  require  the  presence  of  organ- 
oms  to  carry  on  the  manufacture  of  the  posion — that  is, 
the  active  agent  in  their  production.     The  cases  we  have 


next  to  consider  present  a  different  clinical  history,  and 
seem  to  depend  on  entirely  different  causes.  Those  we 
have  been  considering  occur  only  after  labor,  and  have 
their  origin  in  conditions  caused  by  labor.  They  occur 
in  isolated  cases,  are  not  infectious,  and  do  not  spread 
through  whole  communities.  In  the  cases  we  have  now 
to  consider  the  disease  may  manifest  itself  before  labor 
has  set  in.  It  seizes  great  numbers  at  the  same  time  ;  it 
observes  cycles  of  development  and  decline,  sometimes 
disappearing  altogether  for  long  or  short  periods  ;  at  its 
onset  it  proves  fatal  to  almost  all  who  are  attacked  by 
it.  as  it  declines  it  becomes  more  mild  in  its  char- 
acter, and  many  of  those  attacked  recover.  In  all  these 
respects  these  cases  resemble  diseases  specific  in  their 
nature,  and  dependent  for  their  development  on  the  ac- 
tion of  a  specific  epidemic  influence. 

The  occurrence  of  fever  before  labor,  which  rapidly 
develops  after  delivery  into  puerperal  fever  of  a  very  fatal 
character,  has  been  noted  and  described  by  many  ob- 
servers. In  the  following  cases  all  the  facts  seem  to  be 
so  fully  verified  as  to  leave  no  room  for  doubt ;  A  lady, 
mother  of  several  children,  residing  in  a  healthy  situa- 
tion, in  a  large  and  well-kept  house,  when  expecting  her 
confinement,  had  one  of  her  children  under  the  care  of 
Mr.  Wheeler  for  club-foot.  Not  feeling  very  well  she 
spoke  to  Mr.  Wheeler  about  herself,  and  he  prescribed 
a  diaphoretic  mixture.  Next  day  Mr.  Wheeler  finding 
the  fever  increasing,  and  knowing  that  she  was  in  hourly 
expectation  of  her  confinement,  advised  her  to  send  for 
her  accoucheur.  Dr.  WilUam  Smyly  now  saw  her,  on 
April  14,  1882.  He  found  her  skin  dry  and  hot ;  her 
pulse,  120  ;  her  temperature,  104°  F.  The  fever  con- 
tinued to  increase  till  the  morning  of  the  15  th,  when 
perspiration  occurred,  and  labor  set  in.  The  child  was 
bom  at  1.30  P.M.  on  the  15th — a  healthy  child,  still 
living.  The  fever  continued;  though  the  temperature 
never  again  reached  103**,  the  pulse  was  abnormally  and 
increasingly  fast.  The  lochial  discharge  became  fetid 
and  the  abdomen  tympanitic.  During  the  night  of  the 
1 8th  violent  diarrhcea  set  in,  with  great  pain.  I  saw  her 
the  following  morning ;  she  had  then  a  very  rapid  and 
small  pulse,  the  abdomen  was  tympanitic,  the  breasts 
flaccid,  the  skin  relaxed,  and  she  was  gulping  up 
mouthfiils  of  coffee-ground  fluid,  and  was  apparently 
dying,  but  rallied  a  little,  and  lived  till  the  next  day — the 
sixth  after  her  confinement.  There  was  no  history  of 
exposure  to  any  zymotic  disease.  Her  infant  was  born 
alive  and  healthy,  and  continued  healthy.  There  was  no 
disease  in  the  house  or  family.  The  child  under  treat- 
ment for  club  foot  was  wearing  a  boot,  and  running 
about  in  perfect  health.  The  fever  manifested  itseS 
before  either  accoucheur  or  nurse  was  in  attendance  or 
labor  had  set  in,  and  ran  its  fatal  course  with  all  the 
characters  of  puerperal  fever. 

Epidemics  of  puerperal  fever  have  been  so  frequently 
snd  so  fully  described  that  it  is  almost  unnecessary  to 
more  than  refer  to  them.  But  there  is  one  epidemic  on 
record  whose  whole  history  can  be  so  clearly  traced  that 
it  is  exceptionally  worthy  of  attention.  It  occurred  in 
Rotunda  Lying-in  Hospital  in  1854  and  1855,  and  has 
been  described  by  the  late  Dr.  McClintock*  with  all  the 
faithfulness,  accuracy,  and  vividness  of  detail  character- 
istic of  him.  Unfortunately  time  will  not  admit  of  my 
giving  more  than  a  brief  outline  of  the  history.  It  was 
the  second  epidemic  Dr.  McClintock  had  witnessed  in 
the  hospital — the  first  being  in  1845,  when  he  was  assist- 
ant under  Dr.  Charles  Johnson,  and  this  one  in  1854-55 
when  he  was  himself  Master. 

The  epidemic  unequivocally  declared  itself  in  the  first 
week  of  December,  1854,  but  not  unexpectedly.  Dr. 
McClintock  says,  for  there  had  been  twelve  or  fourteen 
cases  of  puerperal  peritonitis  and  phlebitis,  together  with 
a  few  isolated  cases  of  scarlatina  and  typhus,  in  the  house 
during  the  preceding  nine  months. 

1  Proceedings  of  DuUin  Obstetrical  Society,  Dublin  Qnarterty  Journal    of 
Medical  Science,  vol.  xix.,  p.  456. 


144 


THE  MEDICAL  RECORD. 


[August  9,  1884 


From  the  beginning  of  December  to  the  14th  of  Feb- 
ruary, 182  vfromen  were  confined — not  half  the  average, 
as  admissions,  except  in  extreme  cases,  were  stopped  in 
the  end  of  December,  and  all  January. 

Of  the  182,  38  or  I  in  5  were  unequivocally  affected, 
and  of  the  38,  17  recovered  and  21  died — making  the 
proportion  of  fatalities  i  in  8  of  all  admitted,  more  than 
tenfold  the  average  of  the  hospital.  In  three  of  these 
cases  the  puerperal  disease  was  complicated  with  scar- 
latina ;  of  these  two  died.  One  woman,  who  was  slowly 
recovering  from  scarlatina,  which  came  on  soon  after  de- 
livery, was  seized  with  symptoms  of  peritonitis  on  the 
tenth  day,  under  which  she  rapidly  sank. 

"It  rarely  happens,"  Dr.  McClintock  says,  **that 
puerperal  fever  breaks  out  in  the  hospital  without  its 
contemporary  appearance  in  private  practice ;  and  it 
never  happens,  I  believe,  that  it  prevails  to  any  extent 
outside  the  hospital  without  appearing  among  the  patients 
within  its  walls.  On  the  late  occasion  I  had  reason  to 
know  that  several  deaths  had  occurred  from  the  disease 
among  women  confined  at  their  own  homes,  and  lacking 
neither  comfort  nor  attention,  before  it  visited  the  hos- 
pital. Nor  since  then  were  its  ravages  confined  to  the 
poor  inmates  of  our  wards,  for  many  women  among  even 
the  upper  classes  of  society  were  carried  off  under  its 
fatal  influence.  During  the  months  of  December  and 
January  no  less  then  twelve  of  such  deaths,  in  and  about 
Dublin,  came  to  my  own  knowledge,  and  I  have  heard 
of  four  or  five  more  in  the  beginning  of  last  month " 
(February,  1855). 

On  the  outset  of  the  fever  in  the  hospital  it  displayed 
uncommon  virulence,  and  the  first  seven  patients  who 
were  attacked  fell  victims  to  its  malignity. 

The  progress  of  the  epidemic  is  shown  by  the  number 
attacked  on  different  successive  days.  Thus,  on  each 
of  the  following  days — viz.,  the  ist,  3d,  4th,  6th,  9th, 
loth,  nth,  and  12th  December,  there  was  one  woman 
seized  with  the  disorder,  three  on  the  13th,  and  three  on 
the  15  th,  and  on  no  subsequent  days  of  this  month  was 
there  more  than  one,  and  on  many  days  not  one  was  at- 
tacked ;  but  in  Febniary  two  were  attacked  on  the  8th, 
two  oh  the  9th,  and  two  on  the  loth. 

With  respect  to  the  period  after  delivery  at  which  the 
patient  was  seized  the  following  are  the  general  results : 
— 2  were  attacked  in  three  hours  from-the  completion  of 
labor,  I  in  four  hours,  i  in  twelve,  1  in  fourteen,  i  in 
seventeen,  and  i  in  twenty-two  hours.  Each  of  these 
seven  cases  terminated  fatally.  One  was  seized  in 
twenty-two  hours  after  delivery,  and  i  in  twenty-three — 
the  former  recovered,  and  the  latter  died.  Thus  we  see, 
of  9  patients  in  whom  the  complaint  manifested  itself 
on  the  first  day  of  childbed  8  died ;  12  were  affected  on 
the  second  day,  6  of  whom  died ;  10  were  attacked  on 
the  third  day,  and  of  this  number  the  complaint  proved 
fatal  to  three. 

Here,  then,  is  a  disease  which  approaches  gradually, 
which  suddenly  acquires  such  force  as  to  make  the  mor- 
tality of  a  hospital  nearly  tenfold,  which  at  its  onset 
caused  the  death  of  all  who  were  attacked  by  it,  which 
affected  the  city  at  large,  which  manifested  itself  some- 
times within  three  hours  of  the  patient's  delivery,  and 
which  gradually  exhausted  its  violence  and  ceased.  Is 
not  this  the  history  of  an  epidemic  ?  Does  it  not  re- 
mind one  of  the  history  of  cholera,  or  of  small-pox, 
epidemics  of  which  are  also  characterized  by  their  gradual 
approach,  marked  by  sporadic  cases,  their  furious  on- 
slaught and  their  gradual  subsidence  indicated  by  di- 
minished violence  and  the  increased  number  of  re- 
coveries ? 

Epidemic  diseases  vary  as  to  the  mode  of  their  com- 
mencement. Generally  their  advent  is  heralded  by  the 
occurrence  of  isolat«d  cases  at  varying  intervals.  It  was 
thus  in  the  epidemic  of  1854-5,  of  which  we  have  been 
speaking,  and  in  that  of  1826,  described  by  Dr.  Collins. 
In  the  epidemic  of  1845,  also  described  by  Dr.  M'Clin- 
tock,  there  were  no  indications  of  its  approach.     Its  in- 


vasion was  sudden  and  unexpected.  It  sometimes  dis^ 
appears  abruptly,  as  in  that  described  by  Dr.  Collins : 
"In  the  year  preceding  my  appointment  as  Master,*' be 
says,  "which  took  place  in  November,  1826,  puerperal 
fever  prevailed  in  the  hospital  to  an  alarming  extent. 
In  the  succeeding  year,  1827,  the  mortality  from  this 
disease  was  slight  Typhus  fever  was,  during  these 
periods,  very  prevalent  in  Dublin,  and  many  cases  of  it 
appeared  in  hospital.  In  1828  the  attack  of  puerperal 
fever  was  much  more  severe,  proving  fatal  to  twenty-onc 
women.  It  continued  to  increase  in  violence  con- 
siderably in  the  months  of  January,  February,  and  March, 
after  which  it  disappeared,  and  for  the  four  remaining 
years  of  my  Mastership  we  did  not  lose  a  single  patient 
firom  this  disease." 

During  these  four  years  10,785  patients  were  de- 
livered in  the  hospital,  of  whom  only  58  died,  which 
is  nearly  in  the  proportion  of  i  in  186,  or  0.54  per 
cent. — the  lowest  mortality  on  record — in  an  equal 
number  of  a  similar  class  of  patients,  as  Dr.  CoUms, 
writing  in  1836,  remarks,  and  now,  in  1884,  the  same 
remark,  I  believe,  holds  good.  The  mortality  of  lying- 
in  hospitals  may  be  taken  as  depending  on  the  extent  to 
which  puerperal  fever  prevails.  For  short  periods, 
when  fever  is  absent,  the  average  is  low,  but  when  the 
observation  extends  over  a  longer  term  the  average  is 
equalized. 

The  whole  mortality  of  the  Rotunda  Hospital,  from 
its  opening  in  1757  to  the  close  of  Dr.  Shekieton's 
Mastership  in  1854,  nearly  one  hundred  years,  was  at 
the  rate  of  1.21  per  cent  As  we  have  just  seen,  dur- 
ing the  four  years  after  the  epidemic  of  1826  it  fell  to 
0.54,  but  during  the  whole  seven  years  of  Dr.  Collins' 
Mastership  it  was  0.96.  During  the  seven  years  of  Dr. 
Evory's  Mastership,  1 794-1800,  it  was  lower,  o.  75.  From 
1 78 1  to  1786  under  Dr.  Rock,  it  was  0.76,  and  in  the  re- 
port  just  published  for  the  year  1883  it  was  0.55. 

Epidemics  of  other  diseases,  small-pox  for  example, 
subside  as  completely  as  did  that  of  puerperal  fever  in 
1826,  but  they  more  frequently  linger  on,  the  epidemic 
influence  getting  less  and  less  active  till  a  new  wave  ap- 
proaches, and    overlaps  that  which  was   disappearing. 
This  seems  to  have  been  the  case  in  the  epidemics  of 
1845  and  1854.    The  report  of  the  hospital  published  by 
Johnston  and  Sinclair  of  the  seven  years  preceding  Dr. 
M'Clintock's  Mastership,  enables  us  to  trace  it.     Un- 
fortunately we  have  no  details  for  1846,   but  in  1847, 
when  Dr.  Charles  Johnson's  Mastership  terminated  and 
Dr.  Shekleton*s  began,  the  disease  was  still  prevalent,  or 
probably  there  had  been  a  recrudescence  of  the  epidemic. 
During  the  months  of  November  and  December  of  that 
year,  with  which  the  report  commences,  the  total  monal- 
ity  was  at  the  rate  of  7.02  per  cent     In  the  following 
year  it  fell  to  1.81  and  continued  to  fall  till   1852,  when 
it  reached  the  minimun}  of  0.56.     The  new  wave  now 
manifested  itself.  .  In   1853  the  mortality  was  0.88 ;  m 
the  beginning  of  1854  it  was  1.13;    and  in  the  latter 
months  of  that  year  the  epidemic,  as  we  have   already 
seen,  was  in  full  force,  and  the  mortality  reached  xi.53 
per  cent 

The  following  tables,  calculated  from  Johnston  and 
Sinclair's  report,  show  the  total  mortality  and  the  mor- 
tality from  puerperal  fever : 

Tablb  I.— Total  Mortality. 

Nov.  &  Dec.  [  •  '7  in    24a  deliveries  =  7.  ca  percent.,  or  i  in    14,23 

1848 33  •*  1.823  *•  =1.81  -  I',    cca 

1849 37  "  2,063  ••  ==1.79  •«  X"    55.7: 

1850 17  •'  1.98a  ••  =0.85  *•  X  .«  iIi.o 

1851 14  ••  a.070  '•  ZZO.67  ••  z'*Z478 

1853 II  ••  1,963  ••  =  0.56  '•  1   '^lyao 

1853 17  "  1.926  •*  =a88  ••  I  •'  H3.3 

1854 19  ••  1,679  •*  =1.13  ••  I  ••    88.3 

Total  ...  165* 


>  An  error  of  a.  owing  to  a  misprint  in  the  Report.    Total  mortality  izom  all 
causes  was  only  163  =  1.85  per  cent. 


August  9,  1 884.  J 


THE  MEDICAL  RECORD. 


145 


Table  U.^Pturperal  Fevtr, 


1847 
Nor.  &  Dec. 
1848.... 
1849.... 
1850.... 

1851 

1852 

1853.... 
1854.... 


>  •  10  cases  of  puerperal  fever,  9  died,  =  90      percent 


43 

IS 
10 

I 


23  • 

=  53-48   • 

19  • 

=  65.55 

a  ' 

=  13.33 

5  • 

=  50 

3  ' 

=z66 

s  • 

=  6a.s 

10  ' 

=  90.9 

In  Dr.  M'Clintock's  report  of  the  epidemic  of  1854-5 
it  appears  the  hospital  was  closed  in  the  latter  part  of 
December  and  all  January.     It  is  not  directly  so  stated, 
but  it  would  appear  that  it  was  opened  again  inlFebruary, 
but  the  disease  showed  itself  among  the  new  set  of  pa- 
tients— two  were  attacked  on  February  8th,  two  on  the 
9th,  and  two  on  the  loth.     We  had  a  similar  experience 
in  the  Coombe  Hospital  in  the  early  part  of  1880.     The 
hospital  was  completely  rebuilt  and  newly  furnished  three 
years  before.     Fever  manifested  itself  m  the  early  part 
of  the  year,  and  in  March  the  hospital  was  closed.     The 
whole  house  was  cleaned,  the  walls  and  ceiling  scraped 
and  whitened,  the  floors  saturated  with  wax  and  turpen- 
tine, and  everything  thoroughly  cleaned.  It  was  re-opened 
in  April,  every  alternate  bed  being  left  unoccupied  ;  again 
the  fever  showed  itself,  and  again  the  house  was  closed. 
The  hospital  consists  of  two  buildings,  about  twentv  yards 
apart  from  one  another.     The  second  building  is  used 
for  gynaecic  cases.     The  patients  were  transposed — the 
gynsecic  cases  were  moved  to  the  labor  wards,  and  all 
nevr  labor  cases  were  taken  into  the  gynaecic  wards ;  but 
again  the  fever  manifested  itself  among  the  labor  cases. 
The  other  patients  (transferred  to  what  was  supposed 
to  be  an  infected  house)  remained  perfectly  healthy.    The 
evidence  here  seems  conclusive  that  the  disease  was  not 
tiie  result  of  "  Hospitalism.*' 

Another  feature  of  the  disease  of  almost  equal  import- 
ance manifested  itself  on  this  occasion,  as  showing  its 
tnie  nature.  As  the  epidemic  subsided,  and  the  patients 
who  were  attacked  began  to  recover,  they  got  pelvic 
cellulitis,  and  at  the  same  time  many  cases  of  the  same 
kind  came  into  the  house  from  among  the  patients  who 
had  been  confined  at  their  homes.  At  first,  suppuration 
and  the  formation  of  abscesses  was  the  rule  in  these 
cases,  but  after  a  little  the  majority  got  well  by  resolu- 
tion.   The  epidemic  had  expended  its  force. 

In  many  of  the  recorded  epidemics  the  occurrence  of 
cases  of  tjrphus  fever  and  of  scarlatina  at  their  beginning 
is  noted,  and  it  might  be  said  that  they  were  epidemics  of 
these  diseases  and  not  puerperal  fever  at  all. 

The  eighty-nine  cases  recorded  by  Dr.  Braxton  Hicks 
in  his  paper  on  "Puerperal  Diseases  "*  may  lead  some  to 
adopt  this  view,  but  a  careful  examination  of  his  cases 
will  show  that  they  prove  only  that  scarlatina  and  other 
(fiseases  may,  and  frequently  do,  occur  in  the  puerperal 
state.  They  occur  in  a  similar  manner  after  surgical  op- 
eradons,  and  seriously  influence  the  result,  but  do  not 
prove  that  puerperal  is  scarlatina  fever,  or  the  converse, 
if  you  sow  thistles  you  will  grow  thistles,  and  if  you  sow 
scarlatina  the  crop  will  be  scarlatina.  One  case  men- 
tioned by  Dr.  McClintock  affords  evidence,  however,  of 
the  clearest  character  that  the  disease  was  not  scarlatina. 
*  A  woman  recovering  from  scarlatina,  which  attacked  her 
soon  after  delivery,  was  seized  with  symptoms  of  perito- 
nitis (phrase  often  used  by  Dr.  McClintock  as  synony- 
mous with  puerperal  fever)  on  the  tenth  day,  under  which 
she  rapidly  sank."  It  must  be  admitted  that  it  is  in  the 
highest  degree  improbable  that  if  the  epidemic  disease 
was  scarlatina  it  would  afiect  a  patient  in  this  manner 
who  was  only  just  recovering  from  the  same  disease.  It 
is  worthy  of  remark  that,  though  he  makes  special  allu- 
sion to  the  health  of  the  children,  and  to  the  absence  of 
trismus  and  convulsions,  which  had  been  of  frequent  oc- 
cun-ence  in  the  epidemic  of  1845,  ^^*  McClintock  does 
Dot  describe  a  singe  case  of  scarlatina  as  having  occurred 
among  the  children  of  the  women  attacked  by  puerperal 

I  TnnMctiont  of  Obstetrical  Society  of  London,  vol.  xii. 


fever.  Nor  can  it  be  said  the  patients  died  too  soon  to 
allow  of  the  appearance  of  the  characteristic  eruption. 
The  eruption  of  scarlatina  appears  on  the  second  day  of 
the  fever.  None  of  the  patients  died  within  this  time  ; 
one  died  in  50  hours  from  the  period  of  invasion,  one  in 
60,  and  two  in  72.  These  were  the  most  rapid  cases. 
Four  or  five  days  was  the  average  time  that  patients  lived 
after  being  seized  with  a  fatal  attack  of  the  fever. 

The  foregoing  evidence  seems  to  me  to  prove  irresist- 
ibly the  existence  of  a  specific  epidemic  influence.  Much 
more  might  be  adduced  to  the  same  effect.  Dr.  I^usk  ' 
tells  us  that  in  the  year  187 r  the  mortality  from  childbed 
in  New  York  was  399  ;  in  1872,  503  ;  in  1873,  43'  5  ^^ 
'874,  439 ;  and  in  1875,  42o«  The  excess  in  the  deaths 
for  1872,  he  says,  was  due  wholly  to  an  increase  in  the 
cases  of  metria,  those  from  ordinary  accidents  remaining 
nearly  the  same  as  in  the  preceding  years.  The  disease 
certainly  did  not  extend  into  the  city  from  the  hospitals 
serving  as  foci,  for  the  mortality  at  Bellevue  Hospital 
was  scarcely  more  than  half  the  usual  average.  There 
was  no  especial  mortality  that  year  from  either  diphtheria, 
erysipelas,  or  scarlatina,  but  the  >^ggregate  mortality  was 
the  largest  known  in  the  history  of  the  city. 

Dr.  Fordyce  Barker,  in  the  recent  discussion  at  the 
New  York  Academy  of  Medicine,  alluded  to  the  great 
puerperal  mortality  of  1872,  and  attributed  it  to  epidemic 
influence.  In  five  of  the  best  wards  of  the  city,  he  said, 
-  in  which  are  the  residences  of  a  great  proportion  of  those 
of  wealth,  and  few  of  the  class  of  dwellings  known  as 
tenement  houses,  with  a  population  of  307,046,  there 
were  eighty  deaths  from  puerperal  fever,  while  in  the 
remaining  wards  of  the  city,  with  a  population  of  605,- 
245,  there  were  but  sixty-three  deaths — that  is,  nearly 
one-third  less,  in  proportion  to  the  population,  than  in 
the  best  parts. 

Epidemic  disease  is  defined  to  be  "a  disease  prev- 
alent among  a  people  or  a  community  at  a  special  time, 
and  produced  by  some  special  cause  or  causes  not  natu- 
rally or  generally  present  in  the  affected  locality,  as  dis- 
tinguished fi-om  an  endemic  disease.'  The  facts  now 
mentioned  seem  to  me  to  prove  that  there  is  a  large 
group  of  puerperal  cases  that  come  strictly  within  this 
definition,  and  that  the  epidemic  thus  constituted  is  a 
specific  disease. 

It  is  taught,  however,  by  many  that  puerperal  fever  is 
nothing  else  but  poisoning  with  septic  matter  from  the 
genital  organs.' 

This  theory  seems  to  me  to  be  defective,  inasmuch  as 
it  does  not  embrace  the  foregoing  facts. 

As  stated  by  Schroeder,  it  involves  the  following  prop- 
ositions : 

1.  Puerperal  fever  is  caused  by  the  absorption  of  septic 
matter  from  the  genital  organs.  It  is  nothing  but 
poisoning  with  septic  matter. 

2.  The  infecting  matter  is  found  everywhere  where 
organic  compounds  decompose.  It  may  be  derived  from 
dead  bodies,  suppurating  wounds,  disintegrating  neo- 
plasms, and  especially  the  secretions  of  diseased  and 
sometimes  also  of  healthy  puerperal  women. 

3.  Fresh  wounds  are  necessary  for  the  absorption  of 
septic  matter.  Wounds  in  a  state  of  granulation  do  not 
absorb,  but  if  the  granulations  be  absorbed,  or  the  sur- 
face of  the  wound  broken,  then  it  becomes  an  absorbing 
surface. 

4.  The  septic  matter  is  never  absorbed  through  the 
intact  skin  or  mucous  membrane,  through  the  lungs  or 
intestinal  canal. 

5.  The  septic  matter  may  be  generated  within  the  pa- 
tient herself— self  or  auto-infection ;  or  be  introduced 
from  without — external  or  hetero-infection. 

6.  Self  or  auto-infection  is  most  likely  to  occur  when 
the  wounds  are  fresh — that  is,  when  at  the  birth  of  the 
child  there  are  already  decomposed  materials,  as  from  a 

»  Science  and  Art  of  Midwifery.    London :  H.  K.  Lewis.     1884, 

s  New  Sydenham  Society*  i  Lexicon. 

*  A  Manual  of  Midwifery.    By  Karl  Schroeder. 


146 


THE  MEDICAL  RECORD. 


{August  9,  1884. 


decomposed  foetus,  gangrene  of  the  soft  parts  established 
before  delivery,  or  when  new  growths,  as  carcinoma, 
rapidly  undergo  decomposition.  Retained  membranes 
and  placentae  are  rarely  the  cause,  because  by  the  time 
they  begin  to  decompose  the  wounds  have  ceased  to  be 
in  an  absorbing  condition. 

7.  Hetero-infection,  or  infection  from  without,  arises 
from  the  direct  application  of  septic  matter  to  recent 
wounds  in  the  genital  organs  by  means  of  the  sponge  or 
linen  used  in  cleaning  the  parts,  by  instruments,  or  by 
the  examining  finger.  It  takes  place  most  frequently 
through  lacerations  in  the  cervix. 

8.  It  may  possibly  be  caused  by  septic  matter  floating 
in  the  air,  but  there  are  no  cogent  reasons  for  such  an 
assumption. 

9.  The  definition  shows  there  is  nothing  specific  in 
puerperal  fever.  It  is  the  same  state  which  is  frequently 
observed  in  surgical  wards,  and  designated  as  erysipelas, 
pyaemia,  ichoraemia,  and  septicaemia. 

Such  is  the  septicaemic  theory  as  to  the  nature  of  puer- 
peral fever.  Those  who  hold  it  look  on  the  disease  as 
preventable,  and  assert  that  its  occurence  is  due  either  to 
ignorance  of  the  precautions  necessary  to  prevent  it,  or 
to  failure  in  seeing  that  such  precautions  are  rigorously 
carried  out.  These  precautions  are  of  a  very  elaborate 
character.  They  have  been  very  fully  set  out  in  a  paper 
read  before  the  New  York  Academy  of  Medicine  in  De- 
cember last,  by  Dr.  Gaillard  Thomas.  They  are  to  be 
put  in  force  in  private  dwellings  of  aU  classes  as  well  as 
in  hospitals.  When  a  confinement  is  expected  the  pa- 
tient's room  is  to  be  carefully  prepared,  all  curtains  and 
upholstery  to  be  removed,  the  ceilings  and  floors  are  to 
be  washed  with  a  solution  of  carbolic  acid  or  bichloride 
of  mercury.  The  bedstead  and  mattress  to  be  sponged 
with  the  sanie  solution.  The  nurses  and  physician  are  to 
take  care  that  all  their  clothing  is  free  from  septic  infec- 
tion. If  they  have  been  exposed  to  the  effluvia  of  septic 
diseases,  such  as  typhus  or  erysipelas,  their  clothing  is  to 
be  changed  and  their  bodies  thoroughly  sponged  with  a 
saturated  solution  of  boracic  acid.  As  labor  sets  in  the 
nurse  is  to  wash  her  hands,  remove  the  dirt  from  under 
her  nails,  and  give  the  patient  an  antiseptic  injection 
every  four  hours.  The  physician  is  also  to  wash  his 
hands  and  attend  to  his  nails ;  and,  after  washing,  both 
doctor  and  nurse  are  to  soak  their  hands  for  several  min- 
utes in  a  solution  of  bichloride  of  mercury.  Labor  being 
complete,  the  third  stage  being  carefully  attended  to,  the 
physician  is  to  examine  the  vulva  of  the  patient ;  if  the 
perineum  have  been  ruptured  it  is  to  be  closed  by  suture; 
if  slight  lacerations  have  occurred  they  are  to  be  dressed 
with  a  solution  of  carbolic  acid  and  persulphate  of  iron, 
and  painted  over  with  collodion.  The  patient  is  to  take 
ergot  three  times  a  day  for  a  week,  to  have  the  vagina 
syringed  out  with  an  antiseptic  lotion  every  eight  hours 
— twice  as  often  if  the  labor  has  been  an  instrumental  or 
difficult  one — and,  ailer  each  syringing,  a  pessary  of 
iodoform  and  cocoa-nut  butter  is  to  be  introduced  into 
the  vagina,  the  nurse  being  careful  to  disinfect  her  hands 
before  every  approach  to  the  genital  tract  of  the  woman. 

In  corroboration  of  their  views,  the  advocates  of  the 
theory  appeal  to  the  results  which  they  have  obtained  by 
adopting  some  such  mode  of  preventive  treatment  as  that 
laid  down  by  Dr.  Thomas.  But  the  history  of  great 
hospitals,  such  as  that  of  Dublin  or  Vienna,  shows  that 
puerperal  fever  will  prevail  and  cause  sad  mortality  at 
times,  and  disappear  again,  and  that  the  conditions 
governing  its  movements  have  not  yet  been  discovered. 
Dr.  Collins'  precautions,  compared  to  those  recommend- 
ed by  Dr.  Thomas,  were  very  simple  indeed.  "  All  the 
beds  in  the  hospital  are  composed/'  he  says,  "  of  straw, 
nor  is  any  one  used  more  than  a  second  time  without  the 
cover  having  been  washed  and  the  straw  renewed.  In 
every  instance  where  the  patient  dies  this  is  at  once  done, 
and,  should  the  most  remote  symptom  oi fever  have  been 
present,  every  article  connected  with  the  bedding  is  in- 
stantly scoured  and  stoved;  the  wood-work  and  floor 


washed  with  the  chloride  of  lime  solution,  and  the  entire 
ward  whitewashed." 

To  these  precautions,  along  with  strict  attention  to 
ventilation,  he  attributes  the  complete  disappearance  of 
puerperal  fever,  and  the  fact  that  his  mortality  during  the 
last  four  years  of  his  Mastership  was  the  lowest  that  had 
ever  been  recorded.  The  gentleman  who  immediately 
succeeded  Dr.  Collins  in  the  Mastership  was  his  near 
relative,  his  pupil  and  assistant,  and  it  may  be  fairly 
assumed  did  not  relax  his  attention  to  the  means  that  had 
been  so  successful  with  his  predecessor  ;  yet  we  find  that 
the  mortnlity  during  his  Mastership  was  nearly  double  the 
total  mortality  of  Dr.  Collins'  Mastership,  more  than  three 
times  that  of  Dr.  Collins'  fours  years'  exemption  from 
fever,  and  the  highest  recorded  in  the  hospital  during  the 
first  hundred  years  of  its  existence. 

The  experience  of  the  Vienna  hospital  is  not  less  re- 
markable. *'  It  is  familiarly  known,"  Dr.  Lusk  tells  us, 
"that  after  Semelweiss  had  introduced  the  practice 
amon^  the  physicians  attending  patients  at  the  large 
lying-m  hospital  at  Vienna  of  washing  the  hands  in  a 
solution  of  chloride  of  lime,  there  was  a  great  diminution 
in  the  mortality  which  prevailed,  notwithstanding  which 
G.  Brann  reports,  however,  that  in  1857,  in  the  month  of 
July,  in  245  deliveries  there  were  17  deaths.  The  fol- 
lowing month  Prof.  Klein  gave  orders  to  suspend  the  use 
of  dismfectants.  By  chance  in  August  there  were  only  6 
deaths  out  of  250  confinements,  and  in  September  of  275 
patients  none  died.  From  1857  to  i860  the  mortality 
was  slight,  though  disinfectants  were  not  used ;  while 
during  the  three  following  years,  in  spite  of  the  system- 
atic and  persistent  employment  of  those  agents,  the 
death-rate  once  more  assumed  formidable  proportions." 

Such  experiences  are  no  doubt  discouraging.  The  pre- 
cautions of  the  present  day  are,  however,  much  more 
elaborate  than  those  of  Collins  and  of  Semelweiss,  and, 
let  us  differ  as  to  our  theories  as  we  may,  we  will  all 
unite  in  the  earnest  desire  that  they  may  prove,  not  only 
still  more  efficient,  but  more  permanent  in  their  efiects. 


CEREBRAL    LOCALIZATION— THE 
FOR  VISION. 


CENTRES 


By  PHILIP  ZENNER,  AM.,  M.D., 


CDiaNNATI,  O. 


The  present  theories  of  cerebral  localization,  which  as- 
sign to  the  various  parts  of  the  cortex  distinct  and  differ- 
ent functions,  are  of  very  recent  origin.  The  teaching 
of  Flourens,  that  the  removal  of  any  portion  of  the  hemi- 
spheres will  affect  all  the  cerebral  functions  alike,  and 
that  therefore  every  part  of  the  cortex  performs  the  same 
functions,  had  complete  sway  in  the  medical  world  for 
nearly  half  a  century.  The  observations  of  Broca,  that 
certain  disturbances  of  speech  were  apparently  caused  by 
lesions  in  a  limited  part  of  the  frontal  lobes,  were  the 
first  to  point  to  tne  incorrectness  of  that  teaching.  Then 
Meynert  made  his  profound  researches  in  the  anatomy 
of  file  brain,  and  with  an  acumen  rarely  equalled,  com- 
bining the  results  of  anatomical  investigations  with  clini- 
cal and  pathological  observations,  concluded  that  the  an- 
terior portion  of  the  hemispheres  possessed  motor,  the 
posterior  sensory  functions.  Hughlings-Jackson,  also, 
through  pathological  and  clinical  studies,  arrived  at  simi- 
lar results  as  to  the  motor  areas.  Lastly,  a  long  series  of 
experiments  in  animals  seemed  to  confirm  previous  re- 
sults, and  to  map  out  with  wonderful  precision  a  new 
cerebral  topography. 

These  theories  of  localization,  arrived  at  by  so  many 
and  independent  methods,  seem  but  a  necessary  corollaiy 
of  a  deeper  insight  into  the  nature  of  psychical  activity. 
Nevertheless  they  have  not  yet  found  general,  or,  at  least, 
not  universal  acceptance.  Some  observations  in  man, 
but  especially  the  experiments  of  an  eminent  physiolo- 
gist— Goltz,  of  Strassburg — have  apparently  afforded  a 
well-grounded  doubt  of  the  correctness  of  what  had  al- 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


147 


most  been  accepted  as  ascertained  facts.     Goltz  arrives 
at  coodasions  very  similar  to  those  of  Flourens. 

In  this  state  of  uncertainty  apparently  existing,  it  may 
ootbewithont  definite  results  to  examine  the  subject 
bom  a  very  limited  standpoint ;  and,  taking  in  considera^ 
tion  all  the  means  of  research,  attempt  to  arrive  at  posi- 
tive conclusions  as  to  the  localization  of  a  single  cerebral 


I  propose  in  these  papers  to  thus  investigate  the  sub- 
ject, the  cerebral  centres  for  vision.  It  wiU  be  my  effort 
to  bring  to  bear  in  that  investigation  all  that  has  as  yet 
been  contributed  that  is  of  value  in  its  elucidation. 
\Vhile  I  attempt  to  treat  the  subject  as  briefly  and  clearly 
as  possible,  I  wish  to  enter  sufficiently  into  detail  to  en- 
able each  reader  to  draw  his  own  conclusions  from  the 
data  given.* 

To  facilitate  our  investigations,  we  will  examine  the 
sabject  from  three  various  standpoints,  that  is,  the  evi- 
dence afforded  by  anatomical,  physiological,  and  patho- 
logical data. 

ANATOMICAL  DATA. 

The  optic  nerves  and  their  prolongations,  the  optic 
tnu:ts,  can  be  followed  with  little  difficulty  into  some  of 
the  large  ganglionic  masses  at  the  base  of  the  brain,  that 
is  die  optic  thalami,  the  anterior  cor|)ora  quadrigemina, 
and  the  external  and  internal  geniculate  bodies.  The 
fibres  passing  to  the  internal  geniculate  bodies,  and 
therefore  these  bodies  themselves,  are  not  connected 
with  the  sense  of  vision.  This  knowledge  is  gained  from 
experimental  and  pathological  observations,  some  of  which 
will  be  mentioned  further  on,  but  need  not  be  considered 
now.  The  other  ganglia  mentioned — the  opric  thalami, 
or  rather  the  nuclei  of  gray  matter,  in  their  posterior 
portions  termed  pulvinar,  the  external  geniculate  bodies, 
and  the  anterior  corpora  quadrigemina — may  then  properly 
be  termed  the  basal  ganglia  of  vision.  From  these 
masses  of  gray  matter  fibres  pass  in  the  corona  radiata 
to  the  cortex  of  the  hemispheres.  Such  fibres  were  al- 
ready clearly  observed  by  Gratiolet  and  described  as  optic 
radiations,  and  were,  at  a  later  period,  more  fully  traced 
oat  by  Meynert.  These  optic  radiations  were  described 
as  passing  from  the  ganglia  at  base  to  the  cortex  of  the 
occipital  and  temporal  lobes ;  but  the  fibres  passing  to 
the  latter  are  apparently  those  coming  from  the  internal 
geniculate  bodies,  and  therefore  are  not  connected  with 
vision.  In  the  most  recent  systematic  ^ork  on  the  anat- 
omy of  the  brain  (Wernicke,  i88f),  the  optic  radiations 
are  described  as  passing  only  to  the  occipital  lobes. 

This  anatomical  exposition  might  be  deemed  sufficient 
for  the  solution  of  our  problem,  and  give  us  the  requi- 
site mformarion  as  to  the  part  of  the  cortex  in  which  is 
sitaated  the  centre  for  vision.  For  the  optic  nerves, 
whose  functions  are  known,  are  distinctly  followed  into 
one  set  of  ganglia,  and  from  the  latter  other  fibres  are 
described  as  passing  to  a  limited  portion  of  the  cerebral 
cortex.  And,  in  fact,  these  anatomical  data  would  be 
quite  sufficient  for  our  purposes  if  every  part  could  be  es- 
Ublished  beyond  a  doubt.  But  we  are  dealing  with  the 
most  intricate  parts  of  the  bodily  organism,  where  facts 
are  largely  inferred  rather  than  clearly  seen  and  proven. 
It  cannot  be  stated  with  certainty  from  the  simple  ana- 
tomical investigations  that  the  fibres  passing  to  and  from 
the  basal  ganglia  are  either  the  immediate  or  mediate 
continuations  of  one  another,  nor  amidst  that  interminally 
intricate  network  of  the  centrum  ovale,  that  the  so-called 
optic  radiations  pass  only  to  the  occipital  lobes.  If  both 
these  £acts  be  proven,  we  then  have  cause  to  admire  the 
success  of  those  indefatigable  anatomists  who  were  first 
to  point  out  great  physiolgical  truths,  but  their  researches 
alone  can  scarcely  be  accepted  as  proving  these  contro- 

^Wbea  writing  dm  paper  I  wms  not  aware  that  the  subject  had  been  previously 
trated  in  a  unuXtx  manner,  but  have  since  received  a  Mrork  of  Mauthner  s  (Gehim 
■d  Aiwe^  1881)  wherein  be  goc«  over  the  same  ground.  But  inasmuch  as  the 
■HtnlnUe  part  of  the  material  here  collected  together  has  been  contributed 
■Me  llaotfanei'B  book  was  published,  I  trust  these  papers  will  not  be  without 
^■^  ia  fWiM  jiiiM  knowledge  of  what  has  already  been  acquired  on  this  subject 
«  RBorinf  any  doH^  Sormedy  entertained. 


verted  points.  But  while  such  difficulties  are  encoun- 
tered in  tracing  out,  by  ordinary  methods,  the  course  of 
nervous  strands  amidst  countless  intermingling  strands 
of  the  same  kind,  we  are  often  greatly  assisted  by  the  re- 
sults of  certain  pathological  changes.  Thus  degener- 
ative changes  may  occur  in  a  single  system  of  nerve 
fibres  which  will  enable  us  to  distinguish  it  fi-om  the 
surrounding  healthy  tissues  and  follow  its  whole  course 
from  its  inception  to  its  termination.  Such  degenerated 
tracts,  subservient  for  anatomical  and  physiological 
studies,  are  sometimes  found  after  pathological  lesions, 
or  may  be  directly  obtained  by  experimental  destruction 
of  tissues.  Waller,  an  English  physiologist,  pointed  out, 
many  years  ago,  the  cause  and  course  of  these  second- 
ary degenerations  in  developed  nervous  tissues.  The 
principle  proclaimed  by  him,  and  since  termed  the  Wai- 
lerian  law,  is  that  nervous  tracts  degenerate  when  separ- 
ated firom  their  nervous  centres.  They  degenerate  in 
the  direction  in  which  they  convey  impulses,  those  con- 
veying centripetal  impulses  in  a  centripetal,  those  convey- 
ing centrifugal  impulses  in  a  centrifugal  direction,  and 
throughout  their  whole  extent  beyond  the  point  of  injury, 
no  matter  whether  they  be  fibres  in  a  peripheral  nerve  or 
in  the  central  nervous  system. 

To  what  extent  this  Wallerian  degeneration  will  assist 
us  in  our  present  anatomical  studies  will  appear  further 
on.  But  far  more  valuable  in  these  investigations  are 
degenerative  changes  following  destruction  of  different 
parts  at  the  earliest  periods  of  extra-uterine  life  ;  for  here 
there  occurs,  in  addition  to  the  secondary  degenerations, 
a  lack  of  development  in  the  tissues,  and  thus  whole  ner- 
vous strands  can  be  more  distincUy  mapped  out.  This 
method  was  first  methodicaHy  instituted  by  von  Gudden, 
of  Munich.  He  enucleated  the  eyes  of  new-born  ani- 
mals, also  removed  various  parts  of  the  brain,  and  when 
the  animals  arrived  at  comparative  maturity,  noted  the 
changes  resulting  firom  these  early  mutilations.  He 
states  that,  when  under  such  circumstances  a  nervous 
tract  is  severed,  it  will  degenerate  throughout  its  whole 
extent.  Also  atrophy  of  nervous  centres  may  follow 
such  injuries.  Thus  in  case  one  centre  is  destroyed 
which  is  a  source  of  excitation  to  another,  then  the  lat- 
ter degenerates.  This  degeneration  in  the  excited  centre 
will  occur  if  only  its  connection  with  the  exciting  one  is 
severed.  But  an  influence  in  the  opposite  direction,  that 
is,  of  the  excited  on  the  exciting  centre  is  not  found.  It 
is  possible  that  this  law  of  Gudden  does  not  properly 
represent  all  the  facts  in  the  case ;  but,  as  we  will  see  im- 
mediately, it  at  least  enables  us  to  differentiate  and  fol- 
low the  course  of  separate  anatomical  tracts.  It  need 
scarcely  be  mentioned  that  we  will  consider  results  thus 
obtained  only  so  far  as  they  throw  light  on  the  centres  of 
sight 

Course  of  the  optic  nerve, — ^The  first  experiments  of 
Gudden  were  performed  for  the  purpose  of  determining 
the  course  of  the  optic  nerves  in  the  optic  chiasms.  Since 
the  time  of  Isaac  Newton  it  has  been  taught  that  in  man 
there  is  a  semi-decussation  of  the  optic  nerves  in  the 
chiasm,  and  only  in  recent  times  was  that  statement  ques- 
tioned, when,  on  the  ground  of  anatomical  investigations, 
Mendelstamm,  Michel,  and  others  concluded  that  there 
was  complete  decussation  of  the  optic  nerves  in  man. 
I  would  not  enter  into  this  question  here,  were  it  not  that 
its  answer  throws  light  upon  some  of  the  final  questions 
with  which  we  have  to  do,  and  that  there  is  a  prevalent 
opinion  that  it  has  not  yet  been  definitely  settied. 

As  above  stated,  the  doubt  cast  upon  previous  belief 
of  semi-decussation  arose  simply  from  anatomical  inves- 
tigations, and  these  are  quite  insufficient  to  decide  this 
matter. 

Meynert,  than  whom  there  has  been  no  abler  researcher 
into  the  cerebral  structures,  after  a  careful  examination 
of  prepared  sections,  stated  that  he  could  not  therefroin 
determine  whether  there  was  complete  crossing,  or  semi- 
decussation of  the  nerves  in  the  chiasm ;  and  Gudden,  in 
explanation  of  this  difficulty,  states  that  in  addition  to 


148 


THE  MEDICAL  RECORD. 


[August  9, 1884, 


the  endless  entanglement  of  the  fibres,  they  pass  from 
higher  to  lower  planes  in  their  course,  and  therefore 
could  not  possibly  be  followed  throughout  an  anatomical 
section.  H.  Mtiller*  asserted  as  a  law  that  in  animals 
with  monocular  vision  there  is  complete  crossing  of  the 
optic  nerves,  and  that  as  the  axes  of  the  eyes  become 
more  nearly  parallel,  and  therefore  there  is  more  complete 
binocular  vision,  there  is  more  nearly  a  semi-decussation  of 
the  nerves  in  the  optic  chiasm.  In  fishes  there  is  com- 
plete crossing  of  the  nerves.  Here  the  crossing  is  very 
evident,  as  the  two  nerves  merely  overlie  one  another  in 
crossing.  Gudden  at  first  believed  that  the  same  was 
true  of  rabbits,  until  his  experiments  taught  him  that  here 
a  small  part  of  each  optic  nerve  passes  into  the  optic 
tract  of  the  same  side,  Gudden*  s  *  experiments  for  the 
purpose  of  determining  the  course  of  the  optic  nerves 
were  first  performed  on  dogs  and  rabbits.  He  enucle- 
ated either  one  or  both  eyes  very  soon  after  birth,  and 
when  the  animals  had  arrived  at  comparative  maturity, 
killed  them  and  carefully  examined  the  removed  parts. 
He  found,  in  dogs,  after  enucleation  of  one  eye,  atrophy 
of  the  corresponding  optic  nerves,  and  reduction  in  size 
'  of  both  optic  tracts,  that  one  being  always  the  smaller 
which  was  on  the  side  opposite  to  the  atrophied  optic 
nerve.  Similar  changes  could  be  produced  by  destruc- 
tion of  the  visual  ganglia.  When  the  left  external  geni- 
culate body,  anterior  corpus  quadrigeminum,  and  op- 
tic thalamus  had  been  destroyed,  there  was  complete 
atrophy  of  the  left  optic  tract,  and  reduction  in  the  size 
of  both  optic  nerves,  the  right  being  smaller  than  the 
left.  If  both  eyes  were  enucleated,  atrophy  of  both 
nerves  and  both  tracts  followed.  These  results  of  Gud- 
den had  been  corroborated  by  various  other  experi- 
menters, some  of  whom  will  be  referred  to  farther  on.  If 
after  them  there  could  be  any  doubt  of  the  semi-decussa- 
tion *  of  the  optic  nerves  in  the  higher  animals,  this  doubt 
would  be  removed  by  the  later  experiments  of  Nicati,* 
in  which,  after  the  median,  antero-posterior  section  of 
the  chiasm  in  cats,  the  latter  still  retained  their  vision. 
Similar  experiments  have  since  been  made  by  Bechterow* 
on  dogs  with  like  results.  Atrophy  of  both  optic  tracts 
in  man,  after  blindness  in  one  eye  and  atrophy  of  the 
corresponding  opric  nerve,  has  been  recorded  by  Gud- 
den,* Adamiik,*  Putscher,"  Marchand,'  Deutschman," 
Burdach,"  and  others,  and  we  will  have  occasion  to  men- 
tion at  a  later  period  cases  in  which  with  disease  of  one 
optic  tract  blindness  on  the  same  side  of  each  eye  was 
ob§9rved  during  life. 

Relation  of  optic  nerves  to  visual  ganglia  and  cerebral 
hemispheres, — We  have  thus  been  enabled  to  follow  the 
course  of  the  optic  nerves  through  the  chiasm  and  optic 
tracts,  and  must  now  attempt  to  follow  the  latter  into  the 
cerebral  ganglia  and  hemispheres.  Their  primary  termina- 
tion is  very  easily  determined.  After  enucleation  of  the 
eyes,  by  the  method  above  mentioned,  there  is  found 
atrophy  not  only  of  the  optic  nerves  and  tracts,  but  also  of 
the  anterior  corpora  quadrigemina,  the  external  geniculate 
bodies,  and  the  posterior  gray  nucleus  of  the  optic  thala- 
mus (pulvinar).  The  atrophy  of  these  ganglia  occurs  so 
uniformly  that  we  need  not  hesitate  in  statmg  that  they 
are  immediately  connected  with  the  optic  nerves,  and 
therefore  directly  related  to  the  sense  of  vision."  For  the 
sake  of  brevity  I  will  hereafter  speak  of  these  ganglia  con- 
jointly as  the  primary  visual  centres.  Our  next  object 
must  be  to  determine  their  relation  to  the  hemispheres. 

1  cited  by  von  Gudden. 

*  Gudden's  contributions  on  diis  subject  appear  chiefly  in  Graefe's  Archives 
vols,  xxi.,  XXV.,  and  xxvi. 

'  Partial  decussatbn  would  be  %.  more  correct  expression.  I  have  here  employed 
the  other^  and  will  continue  to  do  so,  as  it  is  almost  always  used. 

*  Archtv.  de  Physiologic,  1878. 

'  Rlin.  Monatsblatt  Augenheilkunde,  Bd.  xxi.,  1883.    Q 

*  Archiv  f.  OphthaL,  Bd.  xxv.,  1879. 
^  Ibid.,  xxvi.,  1880. 

a  Ibid. 

*  Ibid.,  Bd.  xxviiL,  1882. 
«o  Ibid.,  Bd.  xxix.,  1883. 
>Ubid. 

IS  In  some  of  the  instances  mentioned,  of  atrophy  of  optic  nerves  in  man  bcins 
followed  by  atrophy  of  both  tracts,  degenerative  changes  in  these  ganglia  on  both 
ides  was  also  observed. 


With  this  object  parts  of  the  hemisphere  were  removed 
in  new-born  animals,  and  after  sufficient  time  had 
elapsed  the  efforts  of  such  mutilations  were  carefully  ob- 
served.  Such  experiments  were  made  by  Gudden*  and 
Ganser,'  of  Munich,  and  Monakow,*  of  St.  Pirmins- 
berg,  Switzerland.  The  results  of  these  experiments  all 
coincided  in  so  far  that  removal  of  the  posterior  part 
of  a  hemisphere  was  followed  by  a  degree  of  atrophy  of 
the  primary  centres  of  the  same  side. 

The  most  valuable  experiments  were  those  of  Mona- 
kow.  He  always  succeeded  in  obtaining  atrophy  of  the 
primary  visual  centres  in  rabbits  after  removal  of  a  very 
limited  portion  in  the  occipital  region,  a  part  correspond- 
ing to  the  area  in  the  dog  which  Munk  has  termed  the 
visual  area,  of  which  we  will  soon  have  occasion  to  know 
more.  Monakow  also  found  that  removal  of  other  parts 
of  the  hemispheres,  while  followed  by  atrophy  of  other 
subcortical  centres,  did  not  affect  the  primary  visual 
centres,  so  that  the  conclusion  appeared  logical  that  the 
latter  are  anatomically  connected  with  a  limited  area  of 
the  cortex  in  the  occipital  region. 

Nevertheless  such  conclusions  might  be  too  hastily 
drawn.  For  in  these  experiments  not  only  is  the  cortex 
removed,  but  the  underlying  white  brain  matter  neces- 
sarily injured,  and  thereby  fibres  may  be  severed  which 
pass  to  other  portions  of  the  brain.  To  avoid  this  source 
of  error  Monakow  resorted  to  another  series  of  very  care- 
ful and  ingenious  experiments  (on  rabbits).  After  re- 
moval of  the  area  in  the  occipital  region  already  refened 
to,  he  found  not  only  atrophy  of  the  primary  visual 
centres,  but  also  atrophy  of  the  fibres  of  the  corona 
radiata  passing  from  this  part  of  cortex  to  these  centres. 
He  now  severed  these  fibres  in  the  midst  of  their  course, 
and  subsequently  observed  the  effects  of  their  division. 
(Operation,  like  the  others,  on  new-bom  animals,  which 
were  then  kept  alive  for  weeks  or  months.)  In  such  in- 
stances there  was  subsequently  found  atrophy  of  the 
severed  fibres  of  the  corona  radiata  both  on  the  periph- 
eral and  central  side  of  the  section — the  same  changes 
in  the  primary  visual  centres  as  after  removal  of  the 
hemispheres — and  atrophy  of  the  corresponding  part  of 
the  cortex.  A  microscopical  examination  of  the  latter 
showed  that  only  a  part  of  the  cortex  was  atrophied— the 
third  and  fifth  layers — those  containing  the  large  pyra- 
midal cells. 

This  experiment  was  made  many  times,  so  as  to  secure 
accuracy  both  as  to  the  locality  and  nature  of  the  changes, 
and  seems  to  leave  no  room  for  doubt  that,  in  rabbits, 
the  primary  visual  centres  are  directly  connected  with  a 
limited  area  in  the  cerebral  cortex. 

The  primary  visual  centres  are,  then,  connected  on 
the  one  side  with  the  cortex  through  fibres  of  the  coroiia 
radiata,  on  the  other,  with  the  retina  through  the  optic 
nerves.  Each  set  of  fibres  probably  terminates  in  these 
ganglia,  and,  it  will  not  be  difficult  to  show,  are  mediately 
or  immediately  connected  with  one  another.  The  atro- 
phied elements  found  in  these  ganglia  after  removal  of 
the  eye  or  cortex  are  different  according  as  the  one  or 
other  is  the  source  of  atrophy.  Some  layers  uniformly 
degenerate  when  the  eye  is  removed,  others  when  part  of 
the  brain  has  been  extirpated.  Nevertheless  there  are 
certain  parts  which  atrophy  alike  from  either  cause,  prov- 
ing the  relationship  of  the  two  systems  of  fibres.*  But 
this  relationship  can  be  more  positively  proven  in  another 
way,  that  is,  by  the  atrophy  found  in  the  optic  nerves 
subsequent  to  removal  of  those  portions  of  the  cortex 
with  which  we  are  now  concerned  It  is  true,  in  rabbits, 
after  removal  of  the  hemispheres  degenerative  changes 
cannot  be  followed  beyond  the  primary  visual  centres. 
But  in  rabbits  the  hemispheres  are  so  little  developed 
that  their  destruction  does  not  appear  to  have  a  far- 


>  Loc.  cit. 

«  Archiv  f.  Psychiarrie,  Bd.,  xiii.,  zSSa. 

»  Ibid.,  Bd.  XIV.  188^. 

*  It  would  lead  too  far  to  enter  further  into  the  subject  here.  I  For  the  micro- 
scopical structure  of  diese  ganglia,  and  the  changes  takuig  place  in  them  in  these  ex- 
perunents,  I  must  refer  to  the  original  work.s  of  Ganscr  and  Monakow. 


August  9, 1884.] 


THE  MEDICAL  RECORD. 


149 


fgg^hing  influence  on  the  peripheral  nerve  structures. 
But  it  is  <l^te  different  in  higher  animals,  where  the 
hemispheres  are  more  fully  developed.  In  a  dog  (Gud- 
den)'  and  in  cats  (Ganser  and  Monakow)  removal  of  a 
hemisphere  was  followed  not  only  by  the  usual  changes 
in  the  primary  visual  centres,  but  also  by  atrophy  of  the 
corresponding  optic  tract,  and  in  both  optic  nerves, 
proving  indubitably  the  direct  relationship  between  the 
hemispheres  and  optic  nerves.  The  exact  portion  of 
the  hemispheres  was  not  determined,  though  in  all  of 
them  the  posterior  part  was  removed.  But  Monakow 
5^eves— inasmuch  as  he  succeeded  with  small  mutila- 
doDS  in  the  occipital  region  in  producing  these  changes, 
while  the  removal  of  large  parts  of  the  frontal  lobes 
caused  no  changes  in  the  optic  nerves — that  the  cortical 
visual  area  is  in  the  same  part  in  cats  and  dogs  as  he 
had  already  located  it  in  rabbits. 

Experiments  have  also  been  made  in  an  opposite  di- 
rection, that  is,  to  determine  the  effect  of  enucleation  of 
the  eye  on  the  cerebral  cortex.  Munk  '  and  Vulpian  ' 
have  observed  atrophy  in  the  occipital  region  as  the  re- 
sult of  such  experiments  (on  dogs),  but  inasmuch  as 
others,  Furstner  *  and  Gudden  *  (on  dogs),  and  Ganser  * 
and  Monakow  ^  (on  cats),  have  obtained  negative  results, 
we  must  leave  this  question  as  still  open.  But  it  is  not 
probable  that  much  can  be  gained  by  such  experiments, 
both  on  account  of  the  improbability  of  decided  changes 
occurring,  and  the  difficulty  of  detecting  them  if  any 
exist 

It  is  quite  justifiable  to  draw  from  the  above  experi- 
ments certain,  though  guarded,  conclusions  ab  to  the 
aoatomical  relations  in  man.  But  Monakow,  to  whom 
we  owe  so  much  of  the  above  researches,  has  also  been 
enabled  to  make  some  observations  on  human  beings 
which  add  to  the  force  of  such  conclusions.  He  had 
an  opportunity  to  examine  the  brain  of  an  eight-months' 
fistus  with  a  parencephalic  defect  in  both  hemispheres. 
There  was  entire  destruction  of  both  occipital  lobes,  and 
of  the  superior  portion  of  the  parietal  lobes,  and,  as 
a  result  (for  everything  pointed  to  its  being  secondary 
to  the  former),  atrophy  of  the  primary  visual  centres  and 
both  optic  nerves  and  tracts.  In  another  case,  a  man 
seventy  years  of  age,  there  was  softenmg  of  the  occipital 
k)be  of  probably  five  years'  standing,  and  also  atrophy  of 
the  corresponding  primary  visual  centres,  and  optic  tract, 
and  nerves.  In  both  these  instances,  it  is  true,  the  dis- 
ease involved  also  the  white  substance  of  the  brain,  so 
that  taken  alone  they  do  not  prove  that  the  affected  por- 
tion of  the  cortex  is  connected  with  the  optic  nerves. 
But  taken  together  with  the  facts,  that,  in  these  instances, 
other  subcortical  centres,  not  in  relation  with  the  occi- 
pital lobes  remained  normal,  these  cases  add  greatly  to 
the  probability  gained  from  the  previous  experiments 
that  the  visual  area  in  man  is  in  the  posterior  portion  of 
the  brain. 

The  only  other  observations  with  which  I  am  ac- 
quainted which  point  directly  to  such  anatomical  rela- 
tions in  man  are  two  cases  reported  by  Hugenin."  In 
these  he  found,  subsequent  to  atrophy  of  the  optic  nerves, 
atrophy  of  the  "  cortex  of  the  occipital  lobes,  where  the 
occipiul  fissure  cuts  into  the  margin  of  the  convexity." 
In  the  first  case,  a  man  fifty-six  years  of  age,  blind 
three  gr  four  ^earsin  the  left  eye,  he  found  these  changes 
in  both  occipital  lobes,  but  more  marked  on  the  side  op- 
posite to  the  affected  eye.  In  the  second,  a  woman 
forty-two  years  of  age,  nearly  blind  in  both  eyes  from  in- 
faicy  (result  of  variola),  he  found  the  same  changes,  but 
alike  on  each  side.  When  reported  a  microscopical 
examination  had  not  been  made. 

^  At  die  dme  Goddca  attributed  the  duwges  in  the  nerves  to  accidentsd  causes, 
■t  die  resoles  of  sabse<]uent  experiments  leave  little  room  for  doubt  diat  there  was 
ktt  a  csasal  irhtionrfiip. 

« tr^tf  ^  Fnctioaen  der  Grosshimrinde. 

*GMb7Maiik. 

*AidiiT£  Pi^cfaiatrie,  188a. 

*IiOc;dL 

*LflcdL 

'LocdL 

'  CorrcspoDdenzbL  f.  Sdiweitxer  Aerxte,  1878,  No.  as. 


These  observations  of  Hugenin  stand  alone.  ^  For 
this  as  well  as  for  other  reasons,  partly  already  re- 
ferred to,  they  cannot  be  accepted  as  more  than  doubt- 
ful evidence  m  our  present  investigation.  Herewith  we 
have  completed  the  first  part  of  our  subject,  the  evidence 
fiirnished  by  anatomical  data  of  the  locality  of  the 
cerebral  centres  of  vision.  A  brief  summary  of  what  has 
been  said  will  give  us  a  clearer  oversight  of  the  subject 

1.  Simple  anatomical  researches  teach  us  that  the 
optic  nerves  enter  the  primary  visual  centres,  and  that 
fibres  pass  from  these  ganglia  to  the  occipital  lobes.  On 
account  of  the  intrinsic  difficulties  of  these  investigations 
they  cannot  be  accepted  as  conclusive. 

2.  Experimental  investigation  has  proven  that  in  higher 
animals  the  optic  nerves  do  not  entirely  cross  in  the 
optic  chiasm.  In  man  the  same  has  been  proven  by 
other  means. 

3.  In  rabbits  experimental  researches  (Monakow)  have 
shown  a  close  relationship  between  the  retinae  and  a 
limited  area  in  the  occipital  region,  the  visual  area  of 
Munk. 

4.  In  higher  animals  (dogs  and  cats)  similar  experi- 
ments have  demonstrated  a  relationship  between  the 
retinae  and  the  posterior  part  of  the  hemispheres.  The 
exact  area  has  not  yet  been  definitely  located,  though  it 
is  probably  the  so-called  visual  area. 

5.  Observations  on  a  human  foetus  and  pathological 
changes  in  an  adult  brain  (Monakow),  together  with  the 
former  considerations,  make  it  highly  probable  that  the 
same  anatomical  relations  exist  in  man. 

6.  Further  evidence  for  this  relationship  in  man  are 
two  instances  (Hugenin)  of  atrophy  of  occipital  lobes 

*  following  atrophy  of  the  optic  nerves.     But  this  evidence 
must  be  accepted  as  of  doubtful  value. 


PRACTICAL  OBSERVATIONS  ON  THE  HUMAN 
EAR  AND  ITS  DISEASES,  WITH  ILLUSTRA- 
TIVE CASES. 

By  SAMUEL  SEXTON,  M.D., 

AUBAL  StfSGBOM  TO  THB  NSW  YOMC  SYB  AMD  BAK  IMTIBMABV.  * 

I. — The  External  Ear. 

(Contiaued  from  No.  7x7,  p.  xaa.) 

It  has  been  claimed  that  a  distinction  should  be  made 
between  othsematoma  and  "  idiopathic  "  perichondritis  of 
the  ear.  They  are  thus  considered  as  separate  and  dis- 
tinct affections  by  Dr.  H.  Knapp,*  who  says  that  "  the 
majority  of  authors  mention  the  inflammarion  of  the 
perichondrium  under  the  head  of  the  much-discussed 
othaematoma,  with  which,  by  Kramer  and  others,  peri- 
chondritis auriculae  is  used  as  a  synonymous  term.*^ 
Dr.  Knapp  presents  a  case  of  the  latter  disease  firom 
which  it  is  alleged  no  blood  at  any  time  escaped  after 
the  cyst  was  punctured,  and  that  it  was  not,  therefore,  a 
case  of  othaematoma.  This  statement,  coming  from  so 
reputable  an  authority,  is  certainly  misleading,  since  it  is 
well  known  that  in  no  case  of  othaematoma  is  perichon- 
dritis absent,  and  that,  moreover,  the  contents  of  the 
tumor  in  ••othaematoma'*  are  firequently  serous. 

A  peculiar  variety  of  othaematoma  remains  to  be 
mentioned  which  is  not  always  easily  distinguishable  from 
hyperaemia,  a  condition  that  I  have  myself  only  met 
with  in  the  insane,  where  it  is  probably  due  to  protracted 
and  violent  rubbing  of  the  auricle.  Any  portion  of  the 
perichondrium  may  be  involved,  but  it  is  usually  limited 
to  a  small  space.  Thickening  is  often  scarcely  observable, 
and  to  the  feel  it  is  not  ••doughy."  The  deep-seated 
nature  of  the  inflamed  or  congested  region,  however,  may 
be  discovered  by  stretching  out  the  auricle  between  the 
observer's  eye  and  a  strong  light.     The  effusion  is  not 

>  Mickel  reported  a  case  with  extensiTe  dianges  in  the  cortex  after  bUndness  of 
probaUy  twenty  years*  duration.  In  this  instance  not  only  are  the  duMftn  very 
dttose,  but  there  is  no  eridence  that  they  were  secondary  to  the  occular  disease. 

«  Perichrondritis  Auriculae,  Archtv.  Otology^  voL  ix.,  p.  195  et  seq.,  1880. 


I50 


THE  MEDICAL  RECORD. 


[August  9,  1884, 


sufficient  to  form  a  tumor ;  such  cases  seem  to  present 
the  characteristics  of  the  first  stage  of  othaematoma.  The 
following  case  is  an  example  of  this  condition. 

Case  V. — Ignatius  J ,  aged  forty,  was  admitted 

to  the  New  York  City  Asylum  for  the  Insane,  August 
18,  1883,  ^^^^  dementia.  Had  to  be  fed  with  stomach- 
tube;  was  a  mere  skeleton.  He  finally  improved 
very  much  mentally  and  physically,  and  on  October 
2 1  St  was  up  and  around  and  eating  and  sleeping 
well.  October  28th,  slight  hsematoma  was  observed  to 
be  developing  in  left  ear  at  inferior  portion  of  concha,  at 
its  junction  with  the  meatus.  My  own  examination, 
on  November  27,  1883,  is  thus  recorded  by  Dr.  Barclay: 
The  left  auricle,  whidi  is  very  thin,  is  of  a  dusky  red 
color.  The  concha,  which  was  naturally  large,  is  much 
thickened  as  far  as  the  meatus,  and  especially  is  it  nar- 
rowed laterally  by  the  thickening  of  its  posterior  and 
inner  wall ;  it  is,  in  fact,  almost  obliterated.  No  saccu- 
lated fluid  was  ever  discovered. 

It  is  notable  in  this  case  that  the  haematoma  came  00 
at  the  stage  of  mitigation  of  chronic  meningitis,  and  thai 
it  was  confined  to  the  concha.  Its  benign  condition 
rendered  treatment  unnecessary. 

Termination, — It  will  be  found  that  among  any  con- 
siderable collection  of  lunatics  or  prize-fighters,  a  very 
considerable  number  have  their  ears  more  or  less  de- 
formed by  previous  attacks  of  othaematoma.  The  writer 
has  found  this  condition  of  things  in  several  large  asy- 
lums for  the  insane ;  and  recently,  in  the  vicinity  of 
Madison  Square  Garden,  on  the  eve  of  a  sparring  exhi- 
bition, he  observed  a  number  of  persons  with  ears  thus 
deformed.  In  some  lunatics,  where  well-marked  deform- 
ity presents  itself  in  one  auricle,  the  other  will  be  found 
so  slightly  deranged  as  to  be  liable  to  escape  detection 
altogether  unless  closely  scrutinized,  and  in  others 
scarcely  any  observable  thickening  will  be  found  in  the 
affected  organ,  the  deeper  coloring  alone  afifording  evi- 
dence to  the  eye,  whilst  the  slight  induration,  thickening, 
and  immobili^  of  the  skin  are  not  to  be  detected  with- 
out careful  handling. 

It  seems  exceedingly  probable  to  the  writer  that  in  cer- 
tain cases  where  the  alienist  is  in  doubt  as  to  the  sanity 
of  a  patient,  valuable  confirmatory  evidence  of  previous 
mental  trouble  might  be  obtained  by  an  examination  of 
the  ears.  Where  3ie  deformity  is  great,  in  consequence 
of  an  extensive  area  of  cartilage  having  been  ex- 
posed by  detachment  of  its  perichondrium,  the  skin 
on  the  outer  surface  will  usually  be  found  to  be  immov* 
able,  whilst  that  on  the  inner  suiiis^qe  remains  unchanged. 
In  these  cases  the  concha  is  liable  to  be  much  reduced  in 
dimensions,  its  posterior  wall  being  often  so  much  thick- 
ened that  a  narrow  vertical  slit  onl^  remains  in  front  of  the 
meatus  extemus,  preventing  the  mtroduction  of  any  but 
a  speculum  of  the  smallest  size.  It  is  scarcely  necessary 
to  add  that  the  deformity  arising  firom  othematoma  is  not 
influenced  by  the  mental  condition  of  the  patient. 

The  characteristic  deformity  resulting  from  othaematoma 
is  well  shown  in  the  following  cases  : 

Case  VI. — Joseph  B ,  admitted  to  the  New  York 

City  Asylum  for  the  Insane,  May,  1883,  was  wild,  mani- 
acal, noisy,  and  violent ;  made  unprovoked  attacks  on  his 
fellow-patients ;  was  put  on  sedatives  and  became  quieter, 
but  began  tearing  his  clothes.  About  June  30th  two  ha&- 
matomas  of  considerable  size  developed.  He  was  then 
excitable,  destructive,  and  filthy.  The  left  haematoma 
ruptured  about  July  9th.  July  30th,  symptoms  of  excite- 
ment, etc,  unabated ;  a  slight  discharge  of  blood  from 
the  ruptured  cyst.  August  30th,  the  left  ear  began  to 
shrivel  up  with  reabsorption  of  the  effused  fluid.  Since 
August  20th  has  given  very  little  trouble,  and  is  now 
(February  4,  1884)  quiet  and  well-behaved.  Both  haema- 
tomas  are  quiet,  and  the  ears  have  a  shrivelled  appearance. 
Fig.  5  shows  the  deformity  of  one  of  the  ears  (the  left). 

Case  VII. — Hugh  S ^  aged  forty-three,  admitted  to 

New  York  City  Asylum  for  the  Insane,  September,  1879, 
Was  demented  for  one  year  before  admission ;  is  noisy 


and  excitable  at  times.  Bodily  condition  not  good,  ^as 
discharged  in  September,  i88o»  and  readmitted  March 
I,  1881.     Is  incoherent ;  prays  a  great  deal — thinks  he 


Fig.  5. 

is  a  great  sinner.  March  loth,  greatly^  excited,  lau^^s, 
talks  and  sings ;  is  filthy.  Excitement  increased  during 
the  summer,  and  in  autumn  his  physical  condition  im- 
proved. He  continued  to  have  ludlucinations,  was  hard 
to  control,  and  tore   his  clothing,  etc.,  up  to  the  time 


Fig.  6. 

the  writer  saw  him,  in  January,  1884.  Fig.  6  shows  the 
condition  of  the  left  ear.*  The  history  gives  no  account 
of  the  time  of  its  appearance  or  progress. 

PATHOLOGY  OF   OTHiCMATOMA. 

After  what  has  been  previously  stated  in  respect  to  this 
affection  there  remains  but  little  to  be  said  concerning  its 
pathology.  Those  interested  in  the  early  attempts  to 
clear  up  the  subject  will  find  the  matter  discussed  by 
M.  Ferris,  Franz  Fischer,  M.  Foville,  Virchow,  and 
others.  There  seems  to  be  but  little  doubt  of  the  ex- 
istence in  many  lunatics  and    inebriates  of  incipient 

1  The  author  is  indebted  to  Dr.  Tnutman  for  the  excelleBt  pholOKFiphs  fion 
which  Figs.  3,  4»  5i  and  6  were  taken. 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


151 


softening  and  disintegration  in  the  tissues  of  the  auri- 
cle, which  predispose  to  separation   of  the  perichon- 
drium from  the    cartilage;   that   this  is  always  a  fac- 
tor of  very    great   importance    in    the    production  of 
othaematoma  may  well  be   doubted,  since   the  disease 
is  scarcely  ever  known  to  occur  in  advanced  life,  when 
such   changes  would   be    greatest,   unless    mechanical 
agencies  intervene.     The  extent  to  which  softening  of 
the  cartilage  may  proceed  without  any  symptoms  mani- 
festing themselves  is  not,  of  course,  known,  but  from  the 
foUowiog    extract    it    is    probably    very    considerable. 
Referring  to  the  pathological  histology  of  the  cartilaginous 
framework   of  the    ear/    Pollak   shows  that  specimens 
*'  which  were  taken  from  the  ears  of  individuals  who  had 
not,  so  far  as  he  could  learn,  been  affected  with  any  form 
of  mental  disease,"  had  *'  in  the  cartilaginous  portion  of 
the  external  meatus,  and  especially  in  the  antihelix,  small 
nodules  "  varying  in  size  **  from  a  mnstard-seed  to  a  lentil." 
These  when  cut  open  showed  to  the  naked  eye  even  a 
departure  from  the  normal  condition  of  the  reticulated 
cartilage,  and  sections  under  the  microscope  were  found 
to  be  deprived  of  the  fibrillated  network  in  places,  and 
instead  there  was  a  structureless  mass.     In  some  peaces 
the  breaking-down    process  was  even   more    marked. 
Where  an  actual  cavity  was  made  out,  it  "  lay  wholly 
within  the  mass  of  cartilage,  and  at  no  point  was  bounded 
by  the  perichondrium^  which  everywhere  appeared  to  be 
perfectly  healthy." 

From  a  recent  examination  of  a  very  considerable 
number  of  cases  of  othaematoma  occurring  in  both  men- 
tally sane  and  insane  subjects,  and  consisting  of  cases  in 
progress  as  well  as  where  recovery  had  taken  place,  the 
writer  entertains  no  doubt  in  his  own  mind  as  to  the 
universal  and  immediate  precedence  of  trauma  in  every 
instance.  That  the  pre-existence  of  the  disintegration 
spoken  of  above  in  the  cartilage  may  influence  the  sub- 
sequent course  of  the  trouble  must  be  admitted.  Othse- 
matoma  occurring  in  pugilists  differs  in  no  respect  from 
that  found  in  lunatics,  its  progress  being  influenced  by 
the  general  condition  and  habits  of  the  patient  in  both 
instances. 

These  tumors  are  formed  of  serum,  or  serum  and  blood, 
which  is  efiiised,  not  under  the  skin,  but  under  the  peri- 
chondrium detached  from  the  cartilage ;  the  contents  are 
not  ordinarily  completely  liquid,  but  are  liable  to  con- 
tain fibrous  or  gelatiniform  clots,  which  if  not  evacuated 
attach  themselves  to  the  internal  surface  of  the  sac  dur- 
ing the  process  of  union  between  the  two  surfaces. 
Union  is  believed  to  finiClly  take  place  by  means  of  an 
exudation  of  plastic  lymph.  It  was  formerly  believed 
that  the  exudation  produced  a  new  formation  of  cartilage, 
sometimes  constituting  a  uniform  layer,  sometimes  small 
patches  only,  which  was  the  cause  of  the  thickening  of 
the  ears.  Virchow,'  however,  alleges  that  the  cartilage  so 
commonly  found  in  these  cases  consists  of  detached  por- 
tions of  greater  or  less  size,Vhich  remain  adherent  to  the 
perichondrium,  and  are  not  of  new  formation. 

In  its  r^ressive  course  the  contents  of  the  tumor  are 
gradually  reabsorbed  or  a  puncture  gives  them  exit,  the 
sni&ces  gradually  come  in  contact,  and  the  outlines  of 
the  cartilage  begm  to  reappear,  but  more  or  less  altered 
in  distinctness.  If  obliteration  of  the  cavity  is  accom- 
plished by  a  moderate  exudation  of  lymph  uniting  its  walls 
the  deformity  will  be  slight,  especially  if  the  tumor  has 
been  but  moderately  distended  by  fluid.  On  the  other 
band,  where  the  perichondrium  has  been  greatly  stretched 
bj  extreme  distention  of  the  sac,  it  contracts  upon  itself 
as  reabsorprion  takes  place,  and  adaptation  to  the  car- 
tilage as  before  cannot  occur;  the  misshapen  appear- 
^tnce  of  the  cartilage  increases  with  the  continued  con- 
traction during  the  process  of  adhesion.  The  ear  finally 
becomes  indurated,  and  the  skin  on  its  outer  surface  is 
omnovable    and    follows   the  outlines  of  the   distorted 


*  MoBUschrift  fOr  OhrenheiDcunde,  July,  187^— Rev.  in  A.  J.  O.,  roU  L,  pp. 
'  nSologie  des  Tumeure,  voL  ii.    Paris,  1867. 


cartilage  underneath.  Sometimes  the  organized  Ijrmph 
which  obliterates  the  cavity  enormously  increases  the 
thickness  of  the  auricle,  an  example  of  which  condition 
is  shown  in  Fig.  6.  Where  a  thin  plastic  layer  only  in- 
tervenes finally,  as  occurred  in  Fig.  7,  the  auricle  is  likely 
to  be  reduced  in  size,  and  becomes  comparatively  thin 
and  shrivelled  ;  in  either  case  permanent  and  character- 
istic deformity  results. 

In  some  cases,  where  the  effusion  has  been  slight  or 
imperceptible  even,  the  plastic  exudation  does  not  form 
a  layer  of  any  great  magnitude ;  the  parts  eariy  are 
found  to  have  a  doughy  feel,  and  but  little  thickening 
is  left  behind ;  the  mobility  of  the  skin  is  less  affected, 
and  consequently  the  ending  deformity  is  scarcely  rec- 
ognizable. 

PROGNOSIS  OF  OTH/CMATOMA. 

This  affection  probably  has  no  prognostic  value  in 
respect  to  the  occurrence,  course,  or  duration  of  in- 
sanity ;  but  its  continuance  may  be  much  influenced  by 
the  congestion  or  bruising  to  which  the  auricle  is  subject 
in  violent  lunatics  and  in  pugilists.  The  trouble  cannot 
be  said  to  augur  against  recovery,  since  it  occurs  in  de- 
mentia when  bodily  health  is  improving,  as  in  Case  V., 
nor  is  it  obnoxious  to  any  particular  form  of  insanity. 
In  Hun*s  reported  cases,  nine  of  the  patients  died  in- 
sane in  the  asylum,  nine  were  discharged  unimproved, 
and  six  remained  when  the  report  was  made— one  of 
them  in  a  state  of  dementia. 

Generally  the  disease  runs  the  course  already  described, 
without  any  complication  that  endangers  life,  although, 
when  extravasated  blood  becomes  putrescent  there  may 
be  danger  of  septic  poisoning.  In  one  instance  occur- 
ring in  the  writer's  practice  (Case  XI.)  the  sympathetic  ir- 
ritation about  the  head  at  one  time  caused  considerable 
anxiety. 

Hearing  undoubtedly  suffers  considerable  impairment 
in  some  cases  through  the  deformity  of  the  outstanding 
cartilaginous  framework  of  the  ear.  In  the  case  of  a 
pugilist  examined  by  the  writer,  whose  auricle  was  greatly 
disfigured,  there  were  permanent  defects  in  this  regard, 
apparently  due  to  the  interference  with  the  normal  ten- 
sion of  the  membrana  tympani — vide  Case  X. 

Recurrence  of  the  tumor  is,  of  course,  impossible, 
where  complete  obliteration  of  the  secreting  surfaces 
has  occurred,  although  repeated  contusions  in  an  auricle 
previously  affected  may  give  rise  to  more  or  less  inflam- 
mation of  the  organ.  In  several  prize-fighters  examined, 
where  the  ears  had  been  previously  the  seat  of  othaema- 
toma, constant  bruising  of  the  organ  seemed  to  occasion 
very  little  local  disturbance. 

TREATMENT  OP  OTILBMATOMA. 

In  the  treatment  of  othasmatoma  in  insane  and  in- 
temperate persons,  among  whom  it  mostly  occurs,  be- 
sides the  diflliculties  encountered  in  controlling  the  ac- 
tions of  the  patient,  mental  disease  and  intemperate 
habits  exert  an  unfavorable  influence,  and  thus  delay 
recovery.  Insane  persons  are  more  obnoxious  to  the 
trouble  when  under  great  excitement,  as  in  acute  de- 
mentia ;  and  their  violent  and  restless  movements  in- 
terfere very  much  with  treatment,  whilst  pugilists  are 
indifferent,  and  generally  neglect  any  advice  given  them. 
It  is  a  safe  rule  in  the  beginning  to  be  in  no  haste  to 
interfere  unless  rupture  of  the  sac  be  imminent,  since  in 
a  certain  number  of  cases  a  manifest  tendency  to  spon- 
taneous recovery  exbts. 

In  laying  out  any  plan  of  treatment  in  this  disease,  it 
will  be  well  to  remember  that  whatever  the  supposed 
cause  or  causes  may  be,  we  have  to  deal  with  a  peri- 
chondritis, in  the  treatment  of  which  we  should  be 
suided  rather  by  its  character  than  by  its  causes.  And 
furthermore,  one  should  be  on  their  guard  in  respect  to 
the  strong  tendency  to  interfere  in  these  cases ;  this  is 
well  expressed  in  a  paper*  on  the  subject  by  Dr.  Wallis. 

*  Log.  ciL 


152 


THE  MEDICAL  RECORD. 


[August  9,  1884, 


This  author  treated  these  tumors  as  abscesses,  and  after 
incision  they  were  poulticed  and  treated  with  stimulating 
lotions,  "  but  almost  always  with  unfavorable  results — 
grangrene,  and  carious  destruction  of  the  cartilage,  and 
not  rarely  death,  was  the  end.'*  This  experience  in- 
duce^  Dr.  Wallis  to  fall  back  on  nutritious  diet,  mild 
cathartics,  and  the  local  application  of  lead  wash — ^in 
all  other  respects  treating  the  swelling  as  a  noli  me  tan^ 
gere.  This  treatment,  continued  for  weeks,  was  success- 
ful in  a  number  of  cases.  Fischer  came  to  the  conclu- 
sion that  eight  weeks*  treatment  affects  neither  the  ter- 
mination nor  the  duration  of  the  disease,  an  opinion 
coinciding  closely  with  the  one  held  by  Marc^,  whose 
belief  was  that  othaematoma*  is  not  influenced  by  any 
treatment,  but  usually  remains  for  about  four  months. 
In  regard  to  the  views  above  cited,  however,  it  should 
be  said  that  the  fatal  results  alluded  to  by  Wallis  are 
quite  exceptional,  similar  experiences  being  unknown  to 
other  writers,  while  Fischer  and  Marc6  seem  to  have 
carried  the  expectant  plan  too  far,  since  no  treatment  is 
notgQoi,  practice  in  all  cases. 

Practically  considered,  othsematoma  has  an  aggressive 
and  a  regressive  period.  All  cases,  however,  do  not 
range  themselves  under  so  arbitrary  a  division,  since  the 
affection  frequently  remains  stationary  for  a  longer  or 
shorter  time,  and  very  often  exacerbations  occur  from 
repeated  contusions  of  the  organ. 

In  its  aggressive  stage  the  observer  seldom  is  offered 
an  opportunity  to  take  cognizance  of  the  incipient 
symptoms ;  especially  difficult  to  detect  is  the  hyperaemia, 
since  the  auricles  are  nearly  always  in  a  congested  state 
in  violent  lunatics  and  inebriates.  Usually  a  tumor 
is  already  found  to  exist,  and  the  first  consideration  will 
then  be  to  limit  its  extension,  if  possible.  If  it  is  found 
that  the  serous  or  sero-sanguinolent  exudation  is  not 
active,  and  that  the  quantity  already  present  is  not  great, 
we  may  prescribe  rest  for  the  patient,  and  administer 
small  and  frequently  repeated  doses  of  th^  tincture  of 
aconite  root  with  a  view  to  arrest  the  activity  of  the 
circulation  of  blood  about  the  head.  Locally  the  affected 
region,  and  beyond  even,  may  be  enveloped  with  a  coat- 
ing of  collodion,  the  gentle  and  uniform  pressure  pro- 
duced by  its  contraction  acting  as  a  compress,  and 
thus  promoting  absorption.  The  following  case,  kindly 
placed  under  my  observation  by  Dr.  W.  A.  Bartlett, 
illustrates  the  treatment  and  progress  of  a  case  of  this 
kind  : 

Case  VIII.— T.  F.  W \  aged  thirty-five,  a  profes- 
sional gymnast,  was  first  seen  on  May  15,  1884.  He 
stated  that  three  weeks  previously  he  had  received  a 
"  cross-counter "  blow  upon  the  left  ear  with  gloved 
hand.  This. gave  rise  to  no  pain,  but,  two  weeks  later 
on,  the  ear  was  again  contused  by  a  powerful  blow  from 
the  foot  of  a  person  in  training.  The  latter  injury  even 
caused  ho  pain  at  the  time,  but  twenty-four  hours  later 
(and  one  week  before  the  writer  saw  him),  after  exer- 
cising for  two  hours  the  auricle  was  observed  to  be  un- 
usually warm,  and  several  physicians  who  happened  to 
be  present  at  the  time  observed  that  it  was  swollen. 
Dr.  Bartlett,  who  saw  the  case  May  nth,  found  a  fluctu- 
ating tumor  on  the  outer  aspect  of  the  pinna  the  size  of 
an  English  walnut,  the  skin  over  it  being  hot  and  tense. 
About  twenty  minims  of  serum  were  withdrawn  by 
aspiration,  the  last  few  drops  of  which  were  tinged  with 
blood.  Afterward  hot  fomentations  were  applied  for  a 
day. 

The  writer  found,  four  days  subsequently  to  the  above, 
a  tumor,  slightly  pinkish  in  color,  seated  at  the  fossa  of 
the  antihelix  \  it  had  spread  itself  almost  equally  in  all 
directions,  encroaching  considerably  on  the  concha.  It 
had  partially  refilled  again,  was  '*  doughy  "  to  the  feel,  but 
not  tender.  Hearing  was  unaffected.  Half  a  drachm  of 
straw-colored  Aiid  was  removed  by  aspiration,  and  the 
tumor  was  painted  over  with  collodion,  the  patient  feeling 
the  pressure.  Small  doses  of  tincture  of  aconite  were 
ordered,  and  rest  was  advised.     The  next  day  the  tumor 


was  softer,  aspiration  was  repeated,  and  the  treatment 
continued,  with  the  addition  of  compression  by  means 
of  padding  of  cotton- wool  and  bandaging.  Tumor  seemed 
to  be  in  statu  quc^  effusion  having  probably  ceased  and 
reabsorption  commenced.  A  notable '  observation  was 
now  made. 

It  was  found  that  the  collodion  contracting  upon  the 
tumor  had  made  it  quite  tense  and  blanched  in  appear- 
ance,  but  that  with  each  pulsation  of  the  anterior  auri- 
cular  artery  (which  supplies  the  anterior  surface  of  the 
auricle)  the  entrance  of  the  blood-supply  was  charac- 
teriztd  by  a  glow  of  deep^ed  colorings  while  the  subsi- 
dence which  succeeded  to  each  diitentioH  was  accompa- 
nied  by  blanching  of  the  parts.  The  pulsations  of  the 
temporal  artery  were  visible  above  and  in  front  of  the 
tragus. 

May  19th. — Tumefaction  much  less ;  the  outlines  of  die 
antihelix  reappearing.  Treatment  continued,  except- 
ing the  aspiration.  May  2  2d,  the  improvement  has 
gone  on  as  before  ;  treatment  same ;  massage  cautiously 
commenced  Progress  was  now  uninterrupted,  the  mas- 
sage being  gradually  increased  in  force  and  frequency. 
By  the  29th  inst.  no  fluid  remained,  the  ''  doughy"  feeling 
was  less,  and  the  collodion  was  omitted.  The  collodion 
during  the  treatment  was  peeled  off  daily  and  a  fresh 
coating  applied.  The  aconite  seemed  to  have  a  notably 
good  effect.  Scarcely  any  deformity  was  observable  at 
this  time,  but  the  concha  was  still  smaller  than  normal, 
and  the  outlines  of  the  antihelix  were  not  sharply  out- 
lined. The  patient  when  discharged  was  directed  to 
continue  the  massage  for  some  time* 

Reabsorption  is  sometimes  retarded  by  the  general 
condition  of  the  patient,  and  it  is  alleged  by  some  au- 
thors that  a  comparatively  scanty  distribution  of  lym- 
phatics characterizes  this  region.  Whenever  this  ten- 
dency manifests  itself,  it  will  be  well  to  employ  measures 
likely  to  hasten  reabsorption.  We  may  act  on  the  pre- 
sumption here  that  the  inflammatory  reaction  frequently 
attending  the  regressive  stage  is  wanting  or  inefficient,  and 
proceed  to  employ  massage  or  pressure.  In  the  writer's 
own  experience  the  latter  has  been  generally  unsatis- 
factory ;  the  application  of  pressure-dressings  being  ex- 
ceedingly difficult,  in  lunatics  especially,  who  are  usually 
unwilling  to  allow  them  to  remain. 

We  can  avail  ourselves,  however,  of  the  massage  treat- 
ment in  all  cases  ;  it  consists  in  pressing  and  rolling  the 
affected  portion  of  the  pinna  between  the  thumb  and 
forefinger  for  some  minutes  or  more  at  a  time.  This 
manipulation  is  usually  unattAided  by  pain,  and,  more- 
over, has  this  advantage,  that  it  can,  when  necessary,  be 
entrusted  to  sane  patients  themselves.  At  first  it  may 
be  practised  once  or  twice  daily,  and  afterward  more 
frequently,  the  length  of  each  stance  being  extended  as 
treatment  progresses. 

The  behavior  of  these  tumors  under  continued  and  even 
severe  bruisings  is  instructive.  Thus  the  writer,  assisted 
by  Dr.  W.  A.  Bartlett,  recently  made  a  study  of  othsema- 
tomata  in  pugilists,  which  showed  that  recovery  was  not 
impossible  under  apparently  unfavorable  conditions,  al- 
though it  should  be  added  that  unsightly  deformity  re- 
mained. The  following  were  among  the  cases  ex- 
amined : 

Case  IX. — John  F ,  twenty-nine  years  of  age,  in- 
temperate, has  been  a  boxer  for  ten  years.  Nine  years 
ago  he  received  a  blow  from  "cross  counter"  upon  left 
ear.  The  auricle  became  swollen,  red,  and  tender, 
the  pain  extending  all  about  the  ear  and  down  the 
neck.  The  tumor  never  opened,  and  became  indurated 
in  about  one  month.  While  the  tumor  remained 
"soft"  it  was  repeatedly  struck  in  boxing  without 
other  effect  than  slightly  increasing  the  local  sensitive- 
ness. After  recovery,  which  took  place  without  treat- 
ment, constant  bruising  failed  to  produce  a  recurrence 
of  the  tumor.  The  outer  surface  of  the  left  auricle  is 
irregularly  nodular — the  fossae  being  obliterated  and  the 
outlines  of  the  ear  completely  destroyed,  with  the  excep- 


August  9, 1884.J 


THE  MEDICAL  RECORD, 


153 


tion  of  the  helix,  which  was  not  affected.  The  auricle  is 
•about  three-fourths  of  an  inch  thick,  and  the  concha  is 
reduced  in  size,  due  to  thickening  of  antitra^s.  The 
posterior  surface  is  nomiaL  The  ear  never  discharged, 
and  hearing  is  good. 

Case  X. — Thomas  A ,  twenty-six  years  of  age, 

has  been  a  boxer  for  many  years.  Received  a  blow 
upon  left  ear  from  '^ cross  counter'*  three  years  ago, 
producing  a  soft,  tender  swelling  of  the  ear,  and  much 
pain  in  the  organ  and  side  of  the  head  and  down  the 
neck.  There  was  also  a  '*  numb ''  feeling  and  autophonia, 
which  remains.  Hot  milk  and  slippery-elm  poultices 
irere  applied  The  tumor  i^as  at  first  purple  in  color, 
afterward  it  became  red.  It  remained  "soft"  for  a 
period  of  five  months,  during  which  time  it  was  frequently 
raptured  by  blows.  Afterward  it  became  hard  and  de- 
formed. The  auricle  is  smooth,  all  of  the  markings  being 
obliterated  except  the  anterior  portion  of  the  helix  which 
is  normal,  and  is  fully  one  inch  in  thickness.  The  pinna 
seems  folded  upon  itself  from  above  downward.  The 
concha  is  impinged  upon  from  behind,  leaving  a  mere 
slit  in  front  of  the  meatus  extemus.  There  is  some 
deafness  in  the  left  ear,  due  doubtlessly  to  the  blow  upon 
the  organ.  The  resulting  deformity  is  similar  to;  that 
shown  in  F^.  6. 

In  resorting  to  methods  calculated  to  increase  absorp- 
tion, however,  care  must  be  exercised  lest  they  increase 
aoduly  the  local  irritation.  In  relation  to  this  matter 
the]^ollowing  paragraph  is  su^estive  :  "  Physiologically 
the  membrane  of  serous  cavities  secretes  a  serous  fluid, 
which  is  taken  up  again  by  the  vessels  with  great  facility, 
this  faculty  of  reabsorption  is  demonstrated  by  the  rapid 
disappearance  of  injected  fluids.  But  if  the  serous 
membrane  is  inflamed,  the  reabsorption  of  an  injected 
fluid  is  impossible  (Rindfleisch),  and  the  irritation  of  the 
serous  membrane  determines  an  abundant  secretion. 
Even  a  slight  irritation  is  sufficient  to  transform  a  serous 
bursa  into  a  cystic  cavity.  Such  a  transformation  of  a 
subcutaneous  serous  bursa  is  known  as  a  hygroma,  and 
may  be  called  a  tumor  because  of  its  tendency  to  persist 
indefinitely."  '  If  extravasation  in  the  begiiming  goes 
on  rapidly,  threatening  to  denude  the  cartilage  more  and 
more,  or  where  reabsorption  comes  to  a  standstill,  an 
aspirating  needle  may  be  inserted  into  its  most  depen- 
dent part  and  the  fluid  evacuated ;  the  subsequent  treat- 
ment should  then  consist  in  the  methods  already  recom- 
mended. The  evacuation  of  fluid  may  be  repeated  as 
often  as  the  sac  refills.  The  operation  can  usually  be 
performed  with  the  ordinary  hypodermic  syringe. 

When  the  tumor  is  large  and  contains  a  considerable 
clot  it  is  best  to  make  an  incision  large  enough  to  per- 
mit the  contents,  including  the  clot,  to  escape,  and,  pince 
fbe  tamor  is  almost  sure  to  refill  again,  a  silk  seton  may 
be  passed  through  the  opening  thus  made  and  brought 
out  agaii^  above,  to  insure  drainage.  The  wounds  hav- 
ing a  strong  tendency  to  reunite  should  be  kept  open  by 
occasionally  drawing  the  seton  through  the  tumor  whilst 
pressing  out  the  contents.  As  soon  as  the  secretion 
lessens,  its  removal  will  be  best  accomplished  by  aspira- 
tion. It  was  formerly  recommended  to  bring  about  ad- 
hesive inflammation  by  keeping  up  irritation  with  the 
seton,  but  thb  can  be  much  better  accomplished  by  mas- 
sage. 

When  the  above  treatment  is  judiciously  employed  we 
may  expect  to  witness  a  gradual  diminution  of  the  tu- 
nor  anid  complete  reabsorption  of  the  fluid  in  three  or 
bnr  weeks ;  and,  moreover,  it  is  believed  that  much  less 
&figQrement  will  ensue  than  occurs  in  cases  allowed  to 
nm  their  course  without  such  aid.  The  longer  an  ac- 
^▼ely  progressing  tumor  is  permitted  to  go  on  toward 
spontaneous  rupture,  the  greater  will  be  the  separation 
of  the  perichondrium  from  the  cartilage,  and  conse- 
quently the  greater  the  ensuing  deformity. 

(To  be  ooatioued.) 
^*  Condi  aad  Rannen :  Padiological  Histology,  pp.  167,  168.     Philadelphia, 


Hepatica — A  Useless  Drug  except  to  Patent 
Medicine  Vendors. — Messrs.  J.  U.  &  C.  G.  Ll<^'d,  of 
Cincinnati,  have  been  investigating  the  subject  of  liver- 
leat  Of  late  years  this  drug  has  been  extensively 
consumed  in  the  preparation  of  certain  proprietary 
medicines.  From  statistics  collected  by  Messrs.  Lloyd 
it  appears  that  last  year  over  340,000  pounds  were  con- 
sumed, of  which  amount  over  300,000  pounds  were  im- 
ported from  Europe.  Four  years  ago  the  entire  con- 
sumption did  not  reach  10,000  pounds.  Our  native 
species  are  named  anemone  acutiloba,  and  anemone 
hepatica,  and  very  closely  resemble  each  other  except  in 
the  shape  of  the  leaves :  the  former  has  sharp  lobes  to 
the  leaves ;  the  latter  blunt  lobes.  Our  Pharmacopoeia 
has  recognized  but  one  species — the  round-lobed  form. 
It  is  proven,  however,  by  Messrs.  Lloyd,  that  nine-tenths 
of  the  native  drug  of  commerce  is  collected  from  the 
«harp-lobed  species,  which  has  never  been  oflicially  rec- 
ognized. The  medical  properties  of  hepatica  are  unim- 
portant. The  plant  does  not  contain  an  active  principle, 
and  is  as  devoid  of  characteristics  as  is  the  grass  of  the 
field.  Of  the  vast  amount  of  the  drug  consumed,  it  is 
creditable  that  the  medical  profession  uses  but  a  small 
per  cent.  Almost  the  entire  lot  is  employed  in  the  prep- 
aration of  certain  secret  remedies. — Drugs  and  Midi- 
<ines  of  North  America  (Cincinnati),  July,  1884. 

Bicarbonate  of  Soda  in  the  Treatment  of  Ton- 
MLUTis. — In  the  early  stages  of  tonsillitis,  before  the 
pain  of  swallowing  is  excessive,  Dr.  Gin6  Partagas  claims 
that  bicarbonate  of  soda  will  arrest  the  inflammation. 
He  makes  the  application  in  the  following  manner :  The 
index  finger  being  moistened  is  charged  with  as  thick  a 
layer  of  the  powder  as  will  adhere  to  it,  and  is  then  intro- 
duced into  the  mouth  and  rubbed  thoroughly  over  the 
inflamed  tonsil.  Five  or  six  applications  are  thus  made 
at  intervals  of  five  minutes,  at  the  end  of  which,  Dr. 
Partagas  claims,  the  patient  will  find  the  act  of  swallow- 
ing nearly  painless.  When  thus  employed  in  the  eariy 
stages,  bicarbonate  of  soda  will  abort  the  disease,  and 
later  will  promote  re^lution.  In  hypertrophy  of  the 
tonsils  two  or  three  applications  of  the  powder  each  day 
will  reduce  the  size  of  the  gland  very  considerably  in  one 
or  two  months.— ^i/r«a/  de  M^decine  ei  de  Chirurgie 
Pratiques,  June,  1884. 

CocAiN. — Dr.  Aschenbrandt,  of  Wttrzburg,  has  made 
some  experiments  on  the  action  of  muriate  of  cocain  on 
the  human  organism.  He  administered  the  drug,  un- 
known to  the  subjects  (who  were  soldiers),  in  doses  of 
about  one-sixth  of  a  grain  in  cases  of  exhaustion  and 
fatigue  from  various  causes,  and  found  invariably  that 
the  lassitude  was  speedily  removed,  and  that  the  men 
could  go  on  for  hours  without  feeling  either  hunger  or 
thirst.  One  of  his  experiments  was  made  on  himself 
after  a  sleepless  night,  with  the  prospect  of  a  long  day's 
march  before  him,  when  a  dose  of  cocain  (taken  in  coffee 
about  3  A.M.)  enabled  him  to  go  the  whole  day  without 
feeling  hunger,  thirst,  or  fatigue,  and  he  dined  late  in  the 
afternoon  with  his  usual  appetite.  He  considers  the 
drug  to  be  a  direct  nerve  food,  and  not  a  stimulant 
merely  ;  but  its  stimulating  action  is  certainly  far  above 
that  of  alcohol,  and  it  appears  to  have  no  injurious  after- 
effects. 

Pagbt's  Disease  of  the  Nipple. — Drs.  Duhringand 
Wile  regard  Paget's  disease  as  an  abnormal  proliferation 
and  degeneration  of  the  rete,  with  secondary  destruction 
of  the  papillae  of  the  corium,  and  subsequent  develop- 
ment of  scirrhus  cancer  of  the  atroph3ring  variety.  The 
cancerous  change  originates  in  the  epithelium  of  the 
smaller  ducts,  and  advances  from  below  upward  and 
outward  as  far  as  the  skin  is  concerned  ;  later  it  attacks 
the  gland  structure ;  and  the  retraction  of  the  nipple  is 
an  early  sign  of  carcinomatous  change. — The  American 
Journal  of  the  Medical  Sciences,  July,  1884. 


154 


THE  MEDICAL  RECORD. 


[August  9,  1884. 


The  Medical  Record 


A  Weekly  JoMrnal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


PUBUSUXD  BY 

WM.  WOOD  i  Co.,  Nos.  56  and  58  Ufayette  Place. 
New  York,  August  9,  z884« 

BABY.FARMING  AS  A  FINE  ART. 

The  unique  feature  of  a  successful  baby-farm,  in  contra- 
distinction with  all  other  institutions,  is  that  the  most 
conclusive  test  of  merit  is  the  small  number  of  the 
graduates.  This  idea  was  aptly  illustrated  by  a  witty 
paragrapher  on  a  Philadelphia  paper,  who  imagined  a  lady 
with  a  burden  in  the  form  of  a  child  going  to  a  profes- 
sional baby-farmer  and  negotiating  for  the  child's  board 
in  the  ^'horne."  In  concluding  the  arrangements  the 
lady  said,  '*But  what  assurance  can  you  give  for  the 
faithful  discharge  of  your  trust  ?  "  Proudly  conscious  of 
her  peculiar  abilities,  the  baby-farmer  made  reply, 
"  Twenty-one  deaths  out  of  a  possible  twenty-three  in 
the  past  six  months."  Needless  to  say,  the  new  patron 
retired  convinced  she  had  made  no  mistake. 

The  subject  no  doubt  is  a  sorry  one  to  make  a  jest  of, 
yet  when  the  humorist  strikes  so  true  a  key  he  may 
easily  be  pardoned  for  its  unseemliness.  Every  one  who 
has  read  of  the  exposures  of  baby«farming  near  this  city 
must  have  noticed  that  the  publication  of  the  facts  as  to 
diet,  attendance,  surroundings,  and  large  death-rate 
does  not  seem  to  lessen  the  number  of  children  in  the 
identical  '*  boarding-houses  "  exposed.  Under  such  cir- 
cumstances it  must  naturally  be  presumed  that  the  per- 
sons placing  children  out  in  this  way  do  not  desire  the 
best,  but  do  desire  the  worst,  accommodations  to  be  ob- 
tained. The  patronage  of  these  farms  comes  not  from 
that  portion  of  the  community  sometimes  called  the 
"lower"  and  *' poorer"  classes.  In  reality,  the  great 
majority  of  these  unhappy  infants  are  the  offspring  of 
well-to-do  fathers  or  mothers,  who,  even  with  the  heart- 
knowledge  of  their  own  immorality  and  crime,  prate  and 
expatiate  upon  the  increase  of  crime  and  laxity  of  morals 
due  to  the  leaven  of  foreign  ideas  in  our  body  politic 
An  incident  in  illustration  was  given  in  The  Evening 
Telegram  one  day  quite  recently.  The  reporter  was  going 
the  rounds  of  the  East  Side  with  a  sanitary  inspector, 
and  in  one  of  the  tenement-houses  on  Orchard  Street 
came  across  this  scene  :  ''  On  the  second-floor  there  was 
a  poor  half-starved  child  seated  in  a  chair  chewing  a 
cracker.  A  man  in  the  room  above  said  the  child  was 
an  adopted  one.  Every  week  an  elegantly  attired  lady 
came  to  see  it.  He  could  tell  no  more  than  that,  but  he 
knew  the  child  was  oi  gentle  birth.  The  doctor  found 
the  woman  who  had  charge  of  the  child,  and  gave  her 
some  medicine  and  a  ticket  to  the  Seaside  Sanitarium." 

One  other  gift  has  the  baby-farmer  who  really  under- 
stands her  business  that  commends  her  to  those  desiring 


her  services,  and  that  is  the  complete  obliteration  of 
identity  a  child  undergoes  after  becoming  a  boarder.  • 
This  phase  of  the  industry,  it  will  be  remembered,  was 
brought  out  in  the  suit  of  Sivillar  Berkely,  claiming  to 
be  the  wife  of  Forrest  S.  Downing,  for  the  recovery  of 
her  child,  who,  she  asserted,  was  in  the  care  of  a  well- 
known  baby-farmer.  The  evidence  in  this  case  was 
strong  on  both  sides,  but  as  might  have  been  expected 
was  against  Miss  Berkely.  Perhaps  under  some  condi- 
tions  needless  to  mention  but  easy  to  infer  the  child 
might  have  been  shown  by  testimony  to  have  been  other 
than  Carlos  Wilson  or  even  Miss  Berkel/s.  An  under- 
taker during  this  trial  testified  that  forty-five  children 
were  buried  in  coffins  precisely  alike  and  the  circum- 
stances of  burial  the  same.  These  conditions  surely 
give  little  opportunity  for  future  recognition,  and  there 
are,  and  may  be,  many  cases  where  some  certain  means 
of  identification  are  needed,  as  in  the  case  cited  above. 

Another  model  establishment  is  the  one  on  One  Hun- 
dred and  Sixty-fourth  Street,  to  which  the  daily  news- 
papers have  devoted  some  attention  within  the  last  two 
weeks.  The  proprietress  of  this  farm  no  doubt  by  this 
time  has  a  heart  swelling  with  gratitude  to  the  press  for 
placing  before  the  public  the  unexcelled  advantages  of 
the  place  she  presides  over.  Then  there  is  the  "  Chil- 
dren's Sanitarium  *'  in  New  Jersey,  near  enough  to  New 
York  to  be  of  some  interest.  The  devoted  guardian  of 
this  charming  retreat  is  the  motherly  Christian  lady  who 
believes  it  needless  to  obtain  a  permit  for  burial  on  the 
decease  of  a  child.  In  this  case,  however,  there  is  some 
hope  of  punishment,  or  Jersey  justice  will  be  belied. 

Some  of  the  baby-fiairmers  must  attain  remarkable  pro- 
ficiency in  their  calling,  if  they  pass  through  the  long  ex- 
perience of  the  old  lady  seventy-six  years  of  age,  who 
applied  for  permission  last  week  from  the  Brooklyn 
Health  Commissioner  to  establish  a  baby-farm.  She 
had  been  in  the  business  thirty  years,  and  as  she  was 
well  recommended  her  desire  was  gratified. 

Still,  with  the  innumerable  evils  of  the  system  so  appar- 
ent, it  is  unjust  to  say  that  all  the  keepers  of  baby-farms 
are  as  heartless  as  they  are  pictured.  Many,  undoubtedly, 
are  even  more  pitiless  than  they  are  painted.  From  the 
very  nature  of  the  business,  the  condition  of  birth,  and 
the  youth  of  the  inmates,  a  large  death-rate  is  to  be  ex- 
pected, even  in  the  establishments  that  have  come  under 
public  notice.  But  when  to  these  are  added  improper 
food,  poor  sanitary  arrangements,  lack  of  care  and  proper 
inspection,  it  becomes  a  frightful  one.  The  whole  aim 
of  the  typical  baby-farmer  is  to  make  as  much  as  possible 
with  the  least  expenditure  of  time,  labor,  and  mopey. 
Whenever  the  domestic  economy  of  one  of  these  places 
has  light  thrown  upon  it  there  is  some  show  of  an  in- 
vestigation. It  subsides,  however,  and  is .  only  thought 
of  when  another  instance  comes  up.  When  one  of  these 
inquiries  is  in  progress  the  baby-farmer  seeks  to  impress 
on  the  minds  of  all  that  she  is  endowed  with  every  in- 
stinct a  perfect  mother  should  display  toward  her  child. 
They  give  the  hearer  the  same  impression  he  would  feel 
listening  to  Madame  Frochard  in  the  '*  Two  Orphans," 
recounting  her  love  and  kindness  for  the  blind  girl 
Louise. 

As  long  as  society  exists  under  its  present  conditions 
it  is  fair  to  suppose  that  baby-farming  will  be  a  fixture. 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


155 


But  if  it  most  be  conducted,  it  should  be  under  a  stern 
and  rigid  inspection,  with  no  opportunity  for  the  escape 
from  punishment  of  those  violating  the  provisions  in  re- 
gard to  it  

SPECIAL  DEPARTMENTS  IN  HOSPITALS. 
We  have  received  the  first  annual  report  of  St  Mary's 
Hospital,  Brooklyn.     The  report  contains  some  facts 
that  win  have  an  interest  to  those  concerned  in  hospital 
managemeDt  and  organization. 

The  medical  and  surgical  staff  numbers  no  less  than 
tfaffty-Zbrn-  persons,  not  including  the  pathologist  and 
curator.    These  gentlemen  preside  over  eleven  different 
departments,  embracing  gynecology,  fractures  and  dislo- 
cations, genito-urinary  surgery,  diseases  of  the  thorax, 
diseases  of  the  abdominal  viscera,  obstetrics,  neurology, 
dBcases  of  children,  and  so  on.     Each  department  has 
its  chief  and  two  or  three  associates.     In  other  words, 
the  cases  are  divided  up  very  much  as  is  done  in  the  city 
dbpensaries,  instead  of  having  simply  a  medical  and 
soigical  service.     This  decidedly  novel  plan   has  now 
been  practically  tried  for  a  year,  there  having  been  617 
patients  treated  during  the  time.     Regarding  its  workings, 
we  cannot  do  better  than  quote  the  words  of  the  report : 
"Whatever  forebodings,  as  to  the  practicability  of 
such  an  arrangement,  may  have  existed  at  the  outset, 
and  while  some  without  due  reflection  viewed  this  new 
departure  with  doubt  or  disfavor,  and  not  a  few  predicted 
non-cohesive  disaster,  the  results  as  set  forth  in  this  first 
annual  report  will,  it  is  hoped,  clearly  prove  not  only  its 
practicability,  but  that  a  high  degree  of  co-operative  ef. 
fidcncy  in  the  professional  service  has  been  effected. 
Tht  history  of  each  patient  on  entering  the  hospital  is 
carcfiilly  recorded,  and  he  or  she  assigned  to  the  appro- 
priate department,  after  which  the  head  or  chief  of  such 
department  assumes  his  or  her  care  and  treatment,  and 
becomes  responsible  and,  in  a  measure,  accountable  to 
the  entire  faculty  as  a  supervisory  body.     In  this  man- 
ner not  only  is  the  professional  work  better  and  more 
orderly  conducted,    and    the    patient,    doubtless,    the 
gainer,  but  the  most  perfect  harmony  exists,  and  each 
member  of  the  hospital  staff  finds  his  intercourse  and  as- 
sociation with  his  colleagues  both  pleasant  and  profitable." 
Certainly  one  year's  experiment  does  not  settle  the 
qoestion  of  the  real  wisdom  of  this  new  plan.     It  will  be 
interesting  to  study  its  workings,  however,  in  connection 
with  the  entirely  opposite  method  pursued  by  certain 
hospitals  in. this  city;  as  for  example  Roosevelt,  where 
^e  is  but  a  single  chief  surgeon  for  the  whole  surgical 
service. 

Bar  it  may  be  inquired  now  whether  the  Brooklyn 
plan  is  not  more  just  to  the  patient  and  physician,  and 
cqnally  fruitful  in  scientific  results. 


CONCERNING  COMMITMENT  TO  INSANE  ASYLUMS. 

Thi  lunacy  laws  of  most  communities  need  overhauling 
in  order  to  provide  proper  security  against  the  incarcera- 
tion in  asylums  of  persons  who  are  not  in  fact  insane. 
This  is  true  in  this  country,  for  there  have  been  within  a 
fev  years  several  remarkable  instances  of  unjust  com- 
BBtment  through  the  cupidity  or  hatred  of  relatives.  The 
same  is  true  also  of  England,  as  will  appear  from  the 
io&owing  statement  of  a  recent  litigation,  which  we  take 


fi-om  one  of  the  legal  journals :  A  case  of  unusual  im- 
portance is  that  of  Weldon  v.  Winslow,  recently  tried  in 
the  Queen's  Bench  Division  of  the  English  Court,  and  in 
which  the  judgment  has  been  reversed  by  the  full  Bench. 
The  action  was  against  Dr.  Forbes  Winslow,  the  alienist ; 
it  was  brought  by  Mrs.  Weldon,  whom  Dr.  Winslow  had 
advised  was  a  proper  subject  for  restraint  in  an  asylum, 
and  whose  husband  he  had  aided  in  endeavoring  to  put 
her  under  such  restraint. 

The  action  was  for  assault  and  also  for  libel — the  as' 
sault  being  the  attempted  restraint,  the  libel  being  hi» 
letter  to  the  husband  sa}'ing  that  immediate  steps  to  se-' 
cure  her  should  be  taken  ;  meaning  thereby,  as  plaintiff 
alleged,  that  such  steps  must  be  taken  to  put  her  in  con-* 
finement  as  a  lunatic. 

The  doctor  relied  for  his  defence  as  to  the  assault  on 
an  order  made  on  certificates  under  lunacy  statutes  ;  and 
as  to  the  libel,  upon  his  privilege,  as  a  physician,  to  write 
such  a  letter  without  malice  and  in  discharge  of  his  duty. 
Mr.  Justice  Manisty,  in  a  lengthy  opinion,  in  which  Justice 
Williams  concurred,  and  which  will  probably  soon  appear 
in  the  current  reports,  condemned  the  course  of  the  de- 
fendant, who  was  the  proprietor  or  manager  of  the  asylum 
to  which  it  was  proposed  to  take  plaintiff,  for  having 
taken  any  part  in  the  arrangements  for  procuring  the 
physicians'  certificate,  and  also  criticised  the  conduct  of 
the  physicians,  who,  instead  of  making  two  separate  and 
independent  examinations,  went  together  to  see  her,  and, 
after  having  an  interview  together  with  her,  took  turns  in 
stepping  out,  that  each  might  make,  what  they  called,  a 
separate  and  independent  examination. 

The  Court  held  that  the  fact  that  those  steps  were 
taken  in  pursuance  of  the  plan  of  sending  the  plaintiff  to 
an  asylum  of  which  the  defendant  was  the  proprietor, 
where  he  would  receive  compensation  for  receiving  her, 
was  sufficient  evidence  of  improper  motive  to  require  the 
submission  of  the  case  to  a  jury,  and  that  the  Judge  at 
the  trial  erred  in  assuming  that  Dr.  Winslow  would  not 
be  actuated  by  sordid  motives,  and  dismissing  the  action 
for  want  of  evidence  to  show  any  improper  motive. 

The  Court  evidently  appreciated  the  eccentricity  of 
.  the  plaintifi;  for  they  said  that  the  great  difficulty  in  the 
argument  of  the  case  had  been  to  get  at  the  facts,  for  the 
plaintiff,  both  at  the  trial  and  on  the  argument  in  the  ap- 
pellate Court,  conducted  her  own  case. 

But  they  rightly  said  that  it  is  not  every  mere  harm- 
less delusion  of  eccentricity  which  requires  a  person  to 
be  confined  in  an  asylum. 

Few  professional  positions  are  more  difficult  and  deli- 
cate than  those  in  which  a  lawyer  or  physician  stands 
when  called  upon  to  advise  upon  a  question  of  this  kind, 
and  to  take  the  necessary  steps  to  secure  commitment. 
The  only  safe  and  right  course  is  for  those  concerned  to 
consult  either  a  medical  man,  or,  better  still,  a  competent 
lawyer  conversant  with  such  subjects ;  in  either  case  se- 
lecting one  who  has  nothing  to  do  with  the  asylum  to 
which  it  is  contemplated  to  commit  the  subject,  and  to 
separate  entirely  the  matter  of  application  for  commit- 
ment from  any  connection  with  the  subsequent  custody 
and  management.  The  convenience  and  saving  of  time 
effected  by  relying  on  the  aid  of  the  physician  of  an  asy- 
lum for  securing  commitment,  is  not  worth  purchasing  at 
the  cost  of  the  mischief  which  may  be  involved. 


156 


THE  MEDICAL  RECORD. 


[August  9,  1884. 


LEPROSY,  AND  ITS  DANGERS. 

Good  results  may  follow  evil  methods,  and  whether  Dr. 
O'Donnell  be  a  charlatan  and  an  alarmist  or  not,  he  has 
excited  interest  in  a  subject  th'at  deserves  the  attention 
of  the  American  people. 

Leprosy  is  not  a  disease  of  which  those  who  are  cleanly 
and  chaste  need  ever  have  any  fear  ;  but  as  a  large  num- 
ber of  American  citizens  possess  neither  of  these  virtues, 
it  is  well  that  they  provide  against  the  contingency  of 
elephantiasis  graeconim.  For  there  is  little  doubt  that 
leprosy  is  contagious,  just  as  syphilis  is  contagious,  i.e.^ 
through  the  agency  of  the  secretions  and  blood.  Among 
licentious  people  it  may  spread  with  rapidity.  The  in- 
fluence of  heredity  is  also  potent  in  increasing  the  num- 
ber of  victims.  Lepers  reproduce  lepers,  though  fortu- 
nately the  second  generation  dies  before  it  can  be  pro- 
ductive. 

The  contagion  of  leprosy,  according  to  Dr.  George 
Thin,  lies  unquestionably  in  the  bacillus  Upra^  first  dis- 
covered by  Hansen.  This  bacillus  resembles  very 
closely  that  of  tuberculosis.  Its  habitat  is  the  lymph  or 
white  blood-corpuscle,  which  it  changes  into  the  leprous 
cell.  It  makes  of  this  an  irritative  body,  producing  the 
peculiar  exudations  and  low  grade  inflammatory  condi- 
tions characteristic  of  the  disease. 

The  parasitic  theory  of  leprosy  is  an  interesting  one, 
and,  if  true,  would  throw  a  new  light  upon  methods  of 
prophylaxis  and  treatment.  It  is  difficult,  however,  to 
explain  satisfactorily  by  this  theory  the  fiauits  of  heredi- 
tary transmission  of  the  disease,  and  especially  such  a 
one  as  is  given  by  Dr.  A.  W.  Saxe.  That  writer  says  : 
The  healthy  wife  of  a  leper  gave  birth  to  a  leprous 
child.  Her  husband  died.  The  still  healthy  widow  mar- 
ried a  healthy  man,  and  gave  birth  again  to  a  leprous  child. 

As  regards  China  and  leprosy,  it  is  to  be  borne  in 
mind  that,  if  we  are  to  legislate  against  the  disease,  we 
must  not  single  out  China.  Leprosy  exists  also  in  Mex- 
ico, the  West  Indies,  India,  Norway,  Sweden,  New 
Brunswick,  Australia,  the  Sandwich  Islands,  Eastern 
Africa — in  fact,  on  the  sea-coast  in  nearly  ail  tropical 
regions. 

In  India  there  are  said  to  be  over  100,000  lepers ;  the 
number  in  China  is  unknown,  but  is  unquestionably 
great.  The  Hawaiians,  of  all  people,  are  most  scourged 
by  it,  nearly  one-tenth  of  the  population  being  affected. 

Four  years  ago  there  were  between  fifty  and  one  hun- 
dred lepers  in  the  'United  States.  Whether  this  number 
has  increased  we  cannot  say.  One  thing  is  certain, 
however,  that  the  disease  cannot  be  spread  by  the 
simple  exhibition  of  cases  of  leprosy  before  the  public. 
However  bad  the  taste  or  useless  and  sensational  the 
object  of  such  a  performance,  it  would  be  as  innocent 
to  public  health  as  the  exhibition  of  a  like  number  of 
cases  of  syphilis. 

The  citizens  of  New  York  who  have  been  so  worried 
over  the  possible  introduction  of  leprosy  into  this  city, 
should  be  informed  that  for  years  there  have  been  one  or 
more  lepers  in  the  city  hospitals,  one  even  having  served 
for  a  time  as  a  nurse  in  Bellevue  Hospital. 

While  leprosy  is  a  disease  about  which  much  is  un- 
known, there  are  certain  facts  that  are  tolerably  well 
established.  These  have  been  formulated  by  Dr.  A.  W. 
Saxe  ("  Report  on  Hawaiian  Leprosy  ")  as  follows : 


"  I.  Leprosy  is  not  a  form  of  syphilis. 

''  2.  It  is  a  specific  and  well-marked  disease. 

"  3.  There  are  two  varieties — the  tubercular  and  anas, 
tkctic  [some  add  a  third,  the  tnacular'], 

"  4.  These  varieties  may  be  distinct  or  associated. 

"  5.  It  is  more  common  in  males  than  females. 

"  6.  It  is  hereditary. 

<'  7.  Itfis  contagious. 

**  8.  It  is  incurable. 

<'  9.  Europeans  are  to  a  certain  extent  exempt  from  the 
disease,  probably  from  greater  precautions  in  avoiding 
the  contagion. 

*'  10.  The  causes  of  the  disease  are  unknown. 

"  Finally,  leprosy  disappears  with  improved  hygienic 
conditions  of  a  people,  cultivation  of  the  soil,  and  ab- 
solute isolation  of  all  lepers." 

In  some  cases,  we  would  add,  the  disease  seems  to 
disappear  despite  the  most  favorable  conditions  forit8 
propagation,  as  has  been  noted  in  the  Virgin  Islands  by 
Dr.  Bonn.  

THE  PROGRESS  OF  THE  CHOLERA. 
The  reports  from  the  cholera-infected  districU  show,  at 
date  of  writing,  that  the  disease  is  unquestionably  de- 
creasing at  Marseilles,  Toulon,  and  Aries..  On  August 
3d,  for  the  first  time  since  the  epidemic  began,  no  deaths 
from  cholera  at  Toulon  were  reported.  The}  number  of 
deaths  daily  in  that  city  has  fallen  to  an  average  of  three 
or  four,  while  the  cases  in  the  hospitals  number  about 
one  hundred. 

At  Marseilles  the  daily  death-rate  has  varied  between 
seven  and  twenty-eight.  The  number  of  new  cases  has 
gradually  fallen. 

On  the  other  hand,  a  few  cases  of  cholera  have  oc- 
curred  at  various  places  in  the  neighborhood  of  the 
stricken  cities,  and  in  several  cities  and  towns  in  Italy. 
A  case  of  cholera  is  also  reported  to  have  occurred  at 
Geneva,  Switzerland. 

The  New  York  Times  has  continued  to  publish  excel- 
lent cable  reports  of  the  cholera^s  progress.  Consul 
Mason,  of  Marseilles,  has  also  given  an  interesting  ac- 
count of  the  development  of  the  epidemic.  This  gen- 
tleman writes : 

"  The  present  situation  may  be,  therefore,  summarized 
as  follows :  The  epidemic  which  now  prevails  at  Mar- 
seilles aind  Toulon  is  Asiatic  cholera,  imported,  beyond 
all  reasonable  doubt,  from  Saigon,  China,  by  the  French 
transport  Sarthe,  to  the  port  of  Toulon.  At  first  the 
disease  was  of  the  type  medically  classified  as  '  benign,' 
but  its  malignity  has  since  increased  by  its  further  dif* 
fiision  and  development  under  the  influence  of  con- 
tinued hot  weather.  At  Toulon  the  epidemic  has  spread 
in  some  degree  to  neighboring  villages,  and  frx>m  Mar- 
seilles it  has  penetrated  as  far  toward  the  interior  as  Aix, 
in  Provence.  The  sea-going  commerce  of  Marseilles  is 
for  the  time  almost  entirely  suspended.  Italy,  Spain, 
Tunis,  and  Algeria,  impose  quarantines  of  from  seven 
to  fifteen  days  upon  all  vessels  from  these  two  mfected 
ports.  Ottoman  ports  absolutely  refuse  entry  to  such 
vessels  upon  any  and  all  conditions.  A  strict  quaran- 
tine of  seven  days  has  been  established  on  the  land  fit)n- 
tiers  of  Italy  and  Spain  against  all  persons  coming  from 
France ;  and  the  conditions  of  these  frontier  quarantines 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


157 


in  respect  to  baggage  and  merchandise  are  daily  becom- 
iog  more  rigid  and  exacting.  Under  these  hopeless  con- 
ditions, nearly  all  the  steamship  lines  between  Marseilles 
ind  other  Mediterranean  and  Eastern  ports  have  sus- 
pended operations,  and  have,  or  will  soon,  close  their 
offices  m  Marseilles.  On  the  French  island  of  Corsica 
no  vessel  from  Toulon  or  Marseilles  is  permitted  to  land 
passengers,  baggage,  or  merchandise.  In  Lyons,  and 
at  the  Paris  terminus  of  the  Paris,  Lyons,  and  Mediter- 
ranean Railway,  all  passengers,  baggage,  and  freights,  as 
well  as  cars  coming  from  Marseilles,  are  fumigated,  dis- 
infected, and  subjected  to  the  strictest  surveillance.'* 

Chairs  of  Hygienk  have  recently  been  established 
at  the  Universities  of  Prague  and  Gratz. 

WiLLARD  Insane  Asylum. — Dr.  P.  M.  Wise  has  been 
appointed  Superintendent  of  the  Willard  Insane  Asylum, 
in  place  of  Dr.  Chapin. 

A  Diagnosis. — '*  Congestion  of  the  right  kidney  "  is 
the  diagnosis  made  by  his  attending  physician  of  an  in- 
disposition from  which  Rev.  Henry  Ward  Beecher  has 
been  suffering. 

Legislating  about  Cholera. — M.  Paul  Bert  has 
proposed  in  the  French  Chamber  a  law  which  compels 
eveiy  doctor  to  report  without  delay  the  appearance  of  a 
case  of  cholera* 

Not  in  Favor  of  Women. — ^The  University  of  Hei- 
delberg has  been  offered  the  sum  of  100,000  marks  on 
condition  that  it  would  admit  women  to  its  courses.  The 
offer  was  refused. 

The  Summer  Sanitary  Corps. — During  the  week 
ending  July  26th  the  summer  corps  of  physicians  visited 
5,328  houses  and  25,536  families,  treated  945  patients, 
and  distributed  2,520  circulars  and  1,085  ^^^^  excursion 
tickets.  Of  the  diseases  treated  463  were  diarrhoeal,  126 
of  lungs  and  throat,  and  59  contagious. 

Suicide  cm  Account  of  Headache. — One  often 
hears  patients  declaring  that  they  will  kill  themselves  if 
die  pains  from  which  they  suffer  continue.  Suicide, 
simply  on  account  of  physical  pain,  is,  however,  rare. 
Recently  such  a  case  was  reported,  the  victim  having 
spparently  suffered  from  brain  tumor.  Only  last  week 
we  referred  to  the  case  of  an  epileptic  who  shot  himself, 
because  of  his  incurable  affliction. 

Cholera  and  the  Migration  of  Birds. — ^A  cable 
dispatch  says :  The  fact  that  the  swallows,  which  migra- 
ted from  Marseilles  at  the  outbreak  of  the  pestilence, 
have  not  yet  returned,  and  that  there  are  no  sparrows  at 
all  in  the  city,  is  adduced  as  evidence  that  the  atmosphere 
is  still  vitiated  This  migration  of  the  birds  has  made  a 
deep  impression  upon  the  public  mind,  and  has  led  to  a 
demand  for  a  purification  of  the  atmosphere  by  means  of 
bonfires. 

A  New  Treatment  for  Ulcer  of  the  Stomach. 
— M.  Debove  proposes  to  treat  gastric  ulcer  by  practi- 
cally annulling  the  function  of  the  stomach.  He  gives 
&e  patient  the  following  dose  three  times  daily  :  Poudre 
deviande,  25  grammes;  bicarbonate  sod»,  10  grammes. 
He  gives  this  generally  by  the  syphon  tube.     In  addi- 


tion he  lets  the  patient  drink  a  litre  of  milk  daily.  It 
is  believed  that  the  alkalinized  food  passes  through  into 
the  intestines  without  exciting  gastric  action. 

A  New  Medical  College  in  the  District  of 
Columbia  has  been  organized  with  the  following  Fac- 
ulty :  Dr.  John  T.  Winter,  Professor  of  Materia  Medica ; 
Dr.  Howard  H.  Barker,  Professor  of  Obstetrics  and 
Dean  of  the  Faculty ;  Dr.  T.  E.  McArdle,  Professor  of 
Surgery;  Dr.  Samuel  F.  Adams,  Professor  of  Theory 
and  .Practice  of  Medicine  -,  Dr.  G.  W.  Cook,  Professor 
of  Physiology  ;  Dr.  G.  William  West,  Professor  of  Anat- 
omy. The  new  college  is  to  be  called  the  Medical  De- 
partment of  the  "  National  University." 

Static  Electricity  as  a  Preventive  of  Cholera. 
— Professor  R.  Vigouroux  contributes  to  Ze  Progrls 
Medical  an  article  upon  the  above  subject.  He  refers 
to  the  experiments  of  Boillot,  Angus  Smith,  and  Chap- 
puis,  which  prove  the  great  disinfectant  properties  of 
ozone.  He  then  shows  that  by  the  static  electrical  bath 
upon  the  insulated  stool  ozone  is  disengaged  most  per- 
fectly and  effectively.  The  electrical  bath  gives  also  a 
stimulus  to  nutrition  which  is  of  importance.  Vigouroux 
concludes  that  a  daily  electrical  bath  on  the  insulated 
stool  is  the  best  prophylactic  against  cholera. 

An  Office  Thief. — Dr.  A.  H.  Friedenberg,  of  this 
city,  writes :  "  Will  you  kindly  allow  space  in  your  jour- 
nal to  warn  your  readers  against  another  office  thief.  He 
is  of  medium  height,  slender,  blonde,  with  a  smooth  face 
and  but  a  small  blonde  mustache;  he  is  a  German, 
speaking  English  fluently,  but  with  a  slight  accent,  well 
dressed  and  genteel-looking,  and  about  nineteen  or  twenty 
years  of  age.  He  follows  the  same  methods  as  his  pre- 
decessors in  his  specialty.  He  must  wait  for  the  doctor, 
or  if  that  is  denied  him,  he  sends  the  servant  on  some 
errand,  while  he  waits  in  the  hall."  He  managed  to  steal 
a  microscope  from  our  correspondent. 

Ammonia  as  a  Prophvlactic  against  Cholera. — 
Dr.  S.  W.  Ingraham,  of  Chicago,  writes :  "  During  the 
years  1865  and  1866  I  spent  much  of  my  time  in  New 
York  City,  and  as  the  cholera  was  quite  epidemic  there 
during  those  two  years  I  took  occasion  to  ascertain  what 
class  of  people  were  least  subject  to  it.  I  found  that  the 
men  who  worked  in  horse  stables  were  rarely,  if  ever, 
attacked  with  the  disease,  and  that  their  families  were 
less  liable  to  the  contagion  than  persons  of  other  occu- 
pations living  in  the  same  localities,  with  the  endemic  in- 
fluences nearly  or  quite  equal.  Upon  special  examination 
I  found  the  clothes  and  even  the  skin  saturated  with  am- 
monia to  such  an  extent  that  when  they  came  in  close 
proximity  to  me  I  could  plainly  discern  its  odoriferous 
properties.  From  this  I  was  led  to  believe  that  their 
whole  bodies  were  more  or  less  under  the  influence  of 
the  ammonia,  and  that  the  cholera  contagion  would  not 
attach  to  them.'' 

Doctors  and  Sanitation. — The  following  will  be  read 
with  interest,  as  it  shows,  if  we  mistake  not,  that  it  is  the 
plumbers  and  architects  who  have  been  the  real  sanitary 
reformers !  Says  The  Sanitary  News :  "  The  great  fault 
of  all  medical  journals  and  practitioners  lies  in  this  fact, 
which  The  Sanitary  News  has  often  endeavored  to  point 
out  to  their  near-sighted  or  averted  gaze,  namely,  that 
the  most  efficient  and  reasonable  sanitary  work  is  accom- 


158 


THE  MEWCAL  RECORD. 


[August  9. 1884. 


plished  by  men  outside  the  medical  profession.  The 
really  useful  and  valuable  sanitary  work  which  conserves 
the  public  health  is  done  by  these  same  *  perpetrating ' 
architects  and  by  plumbers,  when  tliey  design  and  execute 
those  measures  which  cheat  the  physician  out  of  his  bill 
by  preventing  the  causation  of  disease  by  defective  drain- 
age, etc.  What  have  the  medical  gentlemen  accomplished 
in  their  own  branch  of  sanitary  work  ?  Have  they  been 
^ble  positively  to  prevent  one  single  disease  ?  "  Will 
pot  our  excellent  contemporary  the  News  now  publish 
some  letters  from  •*  A  Plumber  to  a  Young  Doctor,"  for 
jexample,  telling  him  how  to  avoid  typhoid  fever,  cholera, 
jsmall-pox,  etc.  ? 

The  Waste  of  the  Medical  Profession,  that  is 
Ko  say  the  number  of  annual  losses  by  death  and  other- 
wise in  Great  Britain  and  Ireland  is,  according  to  Sir 
^yon  Playfair,  about  1,600.  The  Lancet  denies  this  and 
says  that  the  number  of  deaths  annually  among  the  twenty 
odd  thousand  British  doctors  is  only  about  525,  while 
jthe  number. newly  registered  is  over  a  thousand  annually. 
Applying  the  same  death  ratio  to  the  United  States  the 
annual  loss  by  death  should  be  between  1,500  and  2,000. 
The  annual  additions  to  the  medical  ranks,  judged  by 
^he  number  of  students  graduated  annually,  is  over  three 
thousand. 

An  English  Cholera  Commission. — The  English 
Government  has  at  last  appointed  a  Commission,  consist- 
of  Dr.  Klein,  F.R.S.,  and  Dr.  Heneage  Gibbes,  to  pro- 
ceed to  India  and  study  the  cholera.  They  are  expected 
to  act  in  conjunction  with  an  Indian  Cholera  Commis- 
sion also  recently  appointed.  It  is  gratifying  to  learn 
that  two  such  well-quali&ed  gentlemen  have  been  ap- 
pointed for  this  important  work.  Still,  although  there  is 
a  broad  field  for  investigation,  one  cannot  but  think  that 
Ihe  English  Government  has  been  vtxy  laggard  in  ap- 
pointing the  Commission,  and  that  its  action  now  re. 
minds  one  of  locking  the  stable-door  after  the  horse  is 
stolen. 

Scientific  Investigation  into  Cholera. — ^The  phy- 
sicians of  Marseilles  have  been  experimenting  with  a 
pumber  of  old  remedies  for  cholera,  and,  as  might  be  ex- 
pected, with  little  success.  Inhalations  of  oxygen  (and 
ozone?)  seem  to  relieve  dyspnoea  somewhat.  Intra^ 
venous  injections  of  saline  solutions  have  done  no  per- 
manent good.  A  Professor  Reitsch,  heretofore  unknown 
to  the  scientific  world,  claims  to  have  accomplished  some 
extraordinary  results.  He  has,  he  says,  successfully  in- 
oculated dogs  with  the  cholera  bacilli  A  correspon- 
dent of  the  Times  takes  the  trouble  to  telegraph  across 
the  Atlantic  that  Professor  Reitsch  has  also  discovered 
a  way  of  studying  the  cholera  microbe  alive  under  the 
microscope  !  It  is  needless  to  say  that  this  in  one  of  the 
first  things  that  the  discoverer  of  this  microbe  himself 
performed.  The  same  wonderful  Professor  has  discov- 
ered an  infallible  way  of  determining  the  severity  of  an 
attack  in  any  case  by  an  examination  of  the  dejections. 
This  method  he  (naturally)  keeps  secret.  We  suspect 
that  Professor  Reitsch  is  a  humbug,  or  else  is  greatly  mis- 
represented by  cable. 

Cholera  and  the  Temperature. — Simultaneously 
with  the  appearance  of  the  first  two  virulent  cases  of 
Asiatic  cholera  at  Marseilles,  there  began  a  period  of  in- 


tense sultry  heat,  which,  with  the  exception  of  one  day 
continued  till  the  last  of  July.  On  the  evening  of  ju^^ 
28th,  this  stifling  heat  was  accompanied  by  dense  swinns 
of  mosquitoes  which  settled  upon  the  lower  part  of  the 
city,  and  were  only  driven  off  by  fires  of  pitch  and  resin 
which  were  lighted  along  the  streets  during  the  night. 
It  is  remembered  that  a  similar  visitation,  accompanied 
by  a  similarly  dead,  stifling  atmosphere,  had  marked  the 
beginning  of  the  great  epidemic  of  1865,  and  this  circum- 
stance,  added  to  the  steady  increase  of  the  disease  at 
both  Toulon  and  Marseilles,  produced  a  panic  which  con- 
tinned  several  days.  During  this  period  many  thousands 
of  people  removed  to  suburban  residences  or  the  interior. 

The  Doctors  and  the  People  of  the  Infected 
Cholera  Districts. — There  is  no  doubt  much  exaggera- 
tion in  the  dispatches  regarding  the  relations  of  the 
people  to  the  doctors  in  the  cholera  districts. 

One  report  says  :  The  lower  classes  dislike  and  oppose 
the  physicians  because  they  have  gotten  the  notion  that 
the  physicians  have  been  instructed  to  help  the  cholera 
along  in  order  to  get  rid  of  the  surplus  population.  A 
paper  read  by  a  physician  in  Berlin  lauding  the  cholera 
as  sweeping  off  beings  unfitted  for  the  struggle  of  exist- 
ence, has  been  widely  reproduced  in  France,  and  has 
helped  to.  prejudice  the  people  against  the  doctors  and  to 
confirm  them  in  their  belief  that  the  government  has 
adopted  views  similar  to  those  of  the  fierlin  essayist.  An 
instance  of  the  popular  hostility  toward  the  physicians 
occurred  in  Marseilles,  July  30th.  A  doctor  was  going 
into  the  slums  to  attend  a  patient,  when  he  was  con- 
fronted by  a  party  of  the  sick  man's  neighbors,  armed 
with  knives,  who  chased  him  away  and  prevented  his 
ministering  to  the  sufferer. 

On  the  other  hand  the  Municipal  Council  of  Marseilles 
has  resolved  to  erect,  in  a  prominent  place,  a  tablet  to 
commemorate  the  noble  self-sacrifice  of  the  doctors  and 
Sisters  of  Charity  who  were  victims  of  the  epidemic  Dr. 
Patras,  who  died  July  31st,  will  have  a  street  named  after 
him. 

THE  SIMS  MEMORIAL  FUND. 

To  the  Medical  Profession  and  Others  thnmghout  the 
World: 

The  great  achievements  of  Dr.  J.  Marion  Sims  call 
for  some  more  lasting  testimonial  than  obituaries  and 
eulogies.  To  him  m^ical  science  is  indebted  for  much 
brilliant  and  original  work,  especially  in  gynecological 
surgery.  Those  who  have  been  benefited  by  his  teach- 
ings and  new  operations,  and  such  as  have  had  the  direct 
advantage  of  his  personal  skill  are  among  the  first  to 
recognize  and  acknowledge  this  debt 

To  him  is  due  the  honor  of  giving  the  first  strong  im- 
pulse to  the  study  of  gynecological  surgery  in  America. 

It  is  believed  that  the  medical  profession  everywhere, 
the  vast  number  of  women  who  owe  their  relief  from 
suffering  directly  to  him,  and  those  who  realize  the 
benefits  he  first  made  possible,  will  gladly  unite  thus  to 
honor  the  man  through  whose  originad  and  inventive  ge- 
nius such  blessings  have  been  conferred  upon  humanity. 

At  the  sugj^estion  of  many  fiiends,  therefore,  the  sub- 
joined committee  has  been  oiganized,  and  it  is  proposed 
that  a  suitable  monument  be  erected  to  his  memory  in 
the  city  of  New  York. 

To  this  end  the  active  cooperation  of  the  medical 
profession  and  the  many  other  firiends  of  Dr.  Sims 
throughout  the  world  is  respectfiilly  solicited.     Contribu- 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


159 


tioDS  d  one  dollar  and  upward  may  be  forwarded  to  the 
journal  i^hich  has  been  constituted  the  treasury  of  this 
(and— The  Medical  Rscord,  New  York. 

FORDYCE  BARKER,  M.D.,  Chairman. 
GEORGE  F.  SHRADY,  M.D.,  Secretary. 

Thobias  Addis  Emmst,  M.D,,  New  York. 

T.  Gaillard  Thomas,  M.D.,  " 

William  T.  Lusk,  M.D.,  '* 

William  M.  Polk,  M.D.,  *« 

Paul  F.  MundA,  M,D.,  *« 

S.  0.  Vander  Poel,  M.D.,  " 

Frank  P.  Foster,  M.D.,  « 

E.  S.  Gaillard,  M.D.,  *< 

Alex.  J.  C,  Skene,  M.D.,  Brooklyn,  N.  Y. 

Samuel  D.  Gross,  M.D,,  Philadelphia,  Pa. 

William  Goodell,  M.D.,  ** 

James  R.  Chadwick,  M.D.,  Boston,  Mass. 

William  H.  Byford,  M.D.,  Chicago,  lU. 

A.  Reeves  Jackson,  M.  D.,       " 

Thad.  a.  Reamy,  M.D.,  Cincinnati,  O. 

C.  D.  Palmer,  M.D.,  " 

George  J.  Engelmann,  M.D.,  St.  Louis,  Mo. 
R.  Beverley  Cole,  M.D.,  San  Francisco^  CaL 
H.  F.  Campbell,  M.D.,  Augusta,  Ga. 
R.  R  Maury,  M.D.,  Memphis,  Tenn. 
K  S.  Lewis,  M.D.,  New  Orleans,  La. 
J.  T.  Searcy,  M.D.,  Tuskaloosa,  Ala. 
R.  A.  KiNLOCH,  M.D.,  Charleston,  S.  C, 
Hunter  Maguire,  M.D.,  Richmond,  Va. 
S.  C.  Btjsey,  M.D.,  Washington,  D.  C.     • 
Harvey  L,  Byrd,  M.D.,  Baltimore,  Md. 
W.  t.  Howard,  M.D.,  " 

D.  W.  Yandell,  M.D.,  Louisville,  Ky. 
Seth  C.   Gordon,  M.D.,  Portland,  Me. 
Frank  K  Beckwith,  M.D.,  New  Haven,  Conn. 
A  W.  Knox,  M.D.,  Raleigh,  N.C. 

L.  W.  Oakley,  M.D.,  Elizabeth,  N.  J. 
A  T.  Woodward,  M.D.,  Brandon,  Vt. 
Albert  H.  Crosby,  M.D.,  Concord,  N.  H. 
K  S.  DuNSTER,  M.D.,  Ann  Arbor,  Mich. 
Alex.  J.  Stone,  St.  Paul,  Minn. 


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J.  T.  Bamett,  M.D.,  West  Haven,        "       1  00 

C.  T.  Baldwin,  M.D.,  Birmingham,     •*       i  00 

Lewis  Barnes,  M.D.,  Oxford,              "       i  00 

W.  J.  Lewis,  M.D.,  Hartford,              "       i  00 

F.  N.  Braman,  M.D.,  New  London,     "       i  00 

W.  C.  Wile,  M.D.,  Sandy  Hook,         "       2  00 

A.  H.  Churchill,  M.D.,  Meriden,        "       i  00 

C.  H.  S.  Davis,  M.D.,         "               «       x  00 

A.  W.  Tracy,  M.D.,            «*               «       i  00 

K  M.  Child,  M.D.,             "               "       i  00 

Anna  J.  Ferris,                    *•                "       i  00 

J.  D.  Eggleston,  M.D.,        "               '*       i  00 

C.  H.  Howland,  M.D.,        «               «       i  00 

E.  W.  Smith,  M.D.,             "               '«       i  00 

W.  R.  Marsden,  M.D.,        "               "       i  00 

E.  T.  Bradstreet,  M.D.,       "               "       i  00 

W.  A.  M.  Wainwright,  M.D.,  Hartford,  Conn 5  00 

J.  T.  Curtis,  M.D.,                        "            "     5  00 

Wm.  D.  Morgan,  M J).,              *'             **     i  00 

J.  A.  Steven,  M.D.,                     "             «*     3  00 

Wm.  C.  Hunter,  M.D.,  New  York 5  00 

J.  G.  Anthoin,  M.D.,  Antrim,  N.H i  00 

Morris  Christie,  M.D.,     "          "     i  00 

W.  D.  Otterson,  M.D.,  Bennington,  N.  H i  00 

M.  H.  Felt,  M.D.,  Hillsboro  Br.,         "    i  00 

Abel  C.  Burnham,  M.D.,  Hillsboro  Br.,  N.  H. . .  i  00 

A.  H.  Crosby,  M.D.,  Concord,  N.  H 5  00 

G.  P.  Conn,  M.D.,            "            "    500 

Geo.  S.  Huntington,  NewYork 5  00 

H.  Genet  Taylot,  M.D.,  Camden,  N.  J 5  00 

D.  P.  Pancoast,  M.D.,          "          '*    5  00 

Jno.  W.  Snowden,  M.I).,  Ancora,     "    2  00 

Henry  A.  M.  Smith,  M.D.,  Gloucester  City,  N.  J.  i  00 

Edwin  Tomlinson,  M.D.,             "             «      «  j  00 

Duncan  W.  Blake,  M.D.,             "            "      '*  i  00 

Albert  P.  Brown,  M.D.,  Camden,  N.  J i  00 

James  A.  Armstrong,  M.D.,  "          "   i  00 

Alex.  M.  Mecray,  M.D.,         "          "    100 

Waiiam  H.  Ireland.  M.D.,      "          "    i  00 

Jno.  K.  Haney,  M.D.,           "           "  • i  00 

Wm.  A.  Davis,  M.D.,             "          "    i  00 

E.  L.  B.  Godfrey,  M.D.,         "          «    i  00 

juan  B.  Gross,  M.D.,              "           "    i  00 


IC)0 


THE  MEDICAL  RECORD. 


[August  9,  188^ 


l^eprortB  0f  3ocUtus. 


^vitialtt  pCjedicaX  Association. 

FIFTY-SECOND  ANNUAL  MEETING, 

HeldinBelfcLst^  Ireland^  Tuesday^  Wednesday^  Thursday^ 
and  Friday^  July  29,  30,  31,  and  August  i,  1884. 


(BY  CABLE  TO  THE  MEDICAL  RECORD.) 


(Conduded  from  page  139.) 


Thursday,  July  31ST — Third  Day. 

The  Council  met  from  9.30  a.m.  to  1 1  a.m.  when  the 
General  Session  was  called  to  order  by  the  President. 

THE  ADDRESS   IN   PHYSIOLOGY 

was  then  delivered  by  Peter  Redfern,  M.D.  {vide  page 
113).  This  was  listened  to  with  marked  attention  by  a 
large  audience.  At  the  conclusion  a  vote  of  thanks  was 
tendered  the  orator. 

THE   REPORT  OF  THE   MEDICAL  REFORM   COMMITTEE 

was  next  presented,  and  after  some  discussion  was 
adopted. 

THE   MEDICAL   ACT   AMENDMENT   BILL 

was  brought  up  and  discussed  by  Drs.  Waters,  Stokes, 
Brown,  O'Connor,  and  others.  The  general  sentiment 
was  against  such  amendments  as  has  been  made  by  those 
really  opposed  to  the  measure.  The  ostensible  intention 
of  the  latter  parties  was  to  thus  impede  its  passage.  The 
main  objects  of  the  bill  are  the  adequate  representation 
of  the  profession  in  the  Council,  the  provision  for  an 
uniform  qualification  for  the  Register  and  the  mainte- 
nance of  safeguards  against  the  assumption  of  illegal  pro- 
fessional titles.     This  bill  was  finally  endorsed. 

After  the  transaction  of  some  miscellaneous  business 
the  Association  then  adjourned  until  Friday. 


Friday,  August  ist — Fourth  Day. 
The  meeting  was  called  to  order  at  10  a.  m.,  when  the 
address  in  obstetric  medicine 

was  delivered  by  Dr.  Geo.  H.  Kidd  (see  p.  141). 

At  the  2  P.M.  session  the  Reform  Committee's  report 
was  reconsidered  and  again  presented,  and  the  points 
therein  discussed  by  various  speakers. 

The  reports  of  the  various  committees  were  then  pre- 
sented and  adopted,  after  which  the  Association  adjourned. 


REPORTS  OF  SECTIONS. 
SECTION  ON  SURGERY. 
Thursday,  July  3 ist — ^Third  Day. 
The  Section  was  called  to  order  at  2  p.m.  by  the  Presi- 
dent, Sir  Wm.  McCormac. 

No  address  on  surgery  was  delivered. 

TRANSPORT   SPLINT. 

Mr.  John  Fagan  demonstrated  his  transport  splint, 
and  also  exhibited  some  cases  upon  which  excision  of 
the  knee  had  been  performed. 


NEW   ELASTIC  TOURNIQUET. 

Dr.  J.  Ward  Cousins  showed  a  new  elastic  toumi. 
quet  and  explained  his  mode  of  application  as  well  as  its 
adaptability  to  a  large  range  of  cases.  Its  principal 
claims  were  simplicity  and  efficiency. 


SECTION  ON   PUBUC  MEDICINE. 

Thursday,  July  3 ist — Third  Day. 

The  Section  was  called  to  order  by  The  President, 
who  delivered  his  address,  taking  for  his  subject  the 

GENERAL  CHARACTER  OF  EPIDEMICS. 

In  the  course  of  his-  remarks  he  referred  to  the  preva- 
lence of  cholera  on  the  Continent,  and  urged  due  vigi- 
lance  on  the  part  of  the  profession  and  Government  of 
Great  Britain  against  the  invasion.  Nothing  was  of  more 
importance  than  the  purification  of  the  drinking-water, 
attention  to  perfect  sewerage,  and  the  free  use  of  disin- 
fectants. In  fact,  the  purer  the  water  of  a  district  the 
lower  was  the  death-rate.  The  labors  of  Pasteur,  Badd, 
and  Koch  were  appropriately  referred  to  and  eulogized 


SECTION  ON  MEDICINE. 

Thursday,  July  3 ist — ^Third  Day. 

The  chair  was  occupied  by  the  President,  Dr.  J,  W.  T. 
Smith,  of  Belfast. 

THE    causative   RELATIONS    OF   PHTHISIS, 

was  introduced  by  Dr.  Douglas  Powell.  His  line  of 
argument  was  against  the  contagiousness  of  the  disease. 

Dr.  J.  Ward  Cousins  disputed  such  an  assumption, 
and  exhibited  an  antiseptic  inhaler,  which  he  claimed  to 
be  efficacious  in  killing  the  infecting  bacilli. 

Professor  Gardiner  spoke  in  support  of  Koch's 
views  in  regard  to  contagion. 

Dr.  Dyce  Duckworth  presented  the  subject  of  "Rheu- 
matoid Arthritis." 


SECTION  ON  PHARMACOLOGY  AND  THEURA- 
PEUTICS. 

Dr.  Shoemaker,  of  Philadelphia,  presented  the  sub- 
ject of 

OLEATES, 

and  urged  a  further  investigation  into  their  nature  and 
action. 


SECTION  ON  OBSTETRIC  MEDICINE. 
Wednesday,  July  30TH — Second  Day. 

The  President  of  the  Section,  after  calling  the  meetiqi 
to  order,  delivered  an  address  in  which  he  defended  thf 
rights  of  obstetric  men  to  operate,  contending  in  thi 
connection  that  no  men  could  be  competent  gynecolo 
gists  who  were  not  surgically  inclined. 


Saturday  was  occupied  in  excursions  to  Giant's  Ca 
way,  Garron  Tower,  Newcastle,  and  other  points  of  i 
terest. 

About  six  hundred  members  were  present  at  the  mc 
ing. 


August  9,  1884,] 


THE  MEDICAL  RECORD. 


161 


THE  AMERICAN   OPHTHALMOLOGICAL 
SOCIETY. 

Tmntiith  Annual  Meeting,  held  July  \6th  and  17M,  at 
the  Grand  Hotel,  Catskill  Mountains,  N,  Y. 

First  Day — ^Wkdnesday,  July  i6th — Morning  Ses- 
sion. 

In  the  absence  of  the  President,  Dr.  W.  F.  Norris,  of 
Philadelphia,  presided 

Dr.  0.  F.  Wadsworth,  of  Boston,  was  elected  to  fill 
the  vacancy  caused  by  the  resignation  of  Dr.  Richard  H. 
Derby,  Secretary  and  Treasurer. 
^  The  first  paper  was  entitled 

irldectomy  in  chronic  iritis, 

by  Dk.  Hasicet  Derby,  of  Boston. 

A  case  in  vrhich  frequent  attacks  of  iritis  had  occurred 
vas  described.  The  patient  had  obtained  relief  from  the 
use  of  atropine.  She  finally  passed  into  the  hands  of 
another  surgeon  who  dii^osed  glaucoma  and  performed 
irideaomy.  After  this  the  attacks  of  iritis  became  less 
fitqucnt  The  doctor,  however,  thought  that  the  ini- 
pro?cment  was  to  be  attributed  more  to  the  natural  ten- 
dency of  the  disease  to  wear  itself  out  than  to  any  good 
^ects  of  the  operation,  and  concluded  that  under  these 
drcnrastances  an  operation  was  not  justifiable. 

Dr.  H.  Knapp,  of  New  York,  stated  that  in  many  in- 
stances recurrent  iritis  stops  spontaneously.  He  would 
restrict  the  operation  of  iridectomy  to  those  cases  in 
rhich  with  the  iritis  there  is  a  tendency  to  cyclitis  and 
glaacoma.  In  genuine  iritis  he  does  not  recommend  the 
operation. 

Dr.  Charles  S.  Bull,  of  New  York,  read  a  paper 
entitled, 

CASES  OF  RESTORATION  OF  THE  EYELID  BY  TRANSPLAN- 
TATION OF  FLAP  WITHOUT  A  PEDICLE  BY  WOLFE'S 
METHOD. 

T?ro  cases  were  reported  in  which  the  upper  lid  was 
the  one  operated  on,  the  flap  being  taken  from  the  front 
of  the  fore-arm,  and  after  being  deprived  of  all  subcuta- 
neons  tissue,  being  placed  on  the  denuded  lid,  and,  when 
Mcessaiy,  held  in  position  with  sutures.  The  dressing 
consisted  of  gold-beaters'  skin,  with  iodoform  gauze, 
boiated  cotton,  and  a  bandage.  This  dressing  was 
left  undisturbed  for  three  or  four  days.  After  this  the 
dressing  was  repeated  every  day,  or  every  other  day. 

In  the  third  case  the  lower  lid  was  operated  on,  the 
flap  being  taken  from  the  anterior  surface  of  the  chest. 
In  those  cases  in  which  sutures  were  applied,  there  was 
a  little  suppuration  at  their  seat,  but  in  all  the  cases  a 
satisfactory  result  was  obtained. 

Dr.  B.  E.  Fryer,  U.  S.  Army,  then  reported 

A  successful  case  of  SKIN  TRANSPLANTATION  WITH- 
OUT A  PEDICLE  TO  THE  LOWER  LID  AFTER  REMOVAL 
OF  AN    EPITHELIOMA. 

In  this  case,  after  removal  of  the  epithelioma  by  ex- 
cision, a  flap  was  taken  from  the  fore-arm  and  applied  to 
the  raw  surface  of  the  upper  lid.  No  sutures  were  ap- 
plied, but  the  flap  was  held  in  position  with  gold-beaters' 
iin  plaster.  Two  layers  of  this  were  applied  and  allowed 
to  dry.  It  was  then  found  that  they  kept  the  edges  of 
fee  wound  in  perfect  apposition.  The  lids  were  stitched 
together  with  fine  silk  sutures.  As  the  patient  in  return- 
ing to  her  home  would  be  exposed  to  cold,  a  pad  of  ab- 
sorbent cotton  was  applied  to  protect  the  part.  This  was 
amoved  on  the  arrival  of  the  patient  at  her  home.  On  the 
oghth  day  the  plaster  was  removed,  and  perfect  union 
foandtohave  occurred.  Three  months  after  the  opera- 
ton  there  had  been  but  slight  contraction.  The  doctor 
W  particular  stress  on  tlus  method  of  dressing  these 
'ounds.  If  the  operation  were  done  at  the  patient's 
•toose  he  would  dispense  with  the  pad  of  cotton. 


CASE  OF  GANGRENE  OF  THE  LID  WITH  SUBSEQUENT 
RESTORATION  OF  TISSUE  WITHOUT  A  PLASTIC  OPERA- 
TION. 

Dr.  Richard  H.  Derby,  of  New  York,  reported  a 
case  which,  when  first  seen,  was  found  to  have  marked 
gangrene  of  the  lower  lid.  The  case  then  passed  from 
observation,  and  was  not  seen  for  four  weeks.  When  he 
returned,  it  was  found  that  the  skin  had  restored  itself 
and  that  there  was  very  little  deformity. 

The  discussion  of  these  papers  was  entered  into  by  Drs. 
Pooley,  Prout,  Harlan,  Little,  Howe,  Andrews,  Lippin- 
cott.  Fryer,  Green,  and  Wadsworth. 

HYSTERICAL    MONOCULAR     BLINDNESS,     WITH    MYDRIASIS 
AND    BLEPHAROSPASM, 

was  the  title  of  a  paper  read  by  Dr.  George  C.  Harlan, 
of  Philadelphia. 

A  case  of  monocular  blindness  was  described,  in  which 
it  was  accidentally  discovered  that  the  blindness,  as  well 
as  the  spasm  of  the  face  which  was  present,  was  much 
benefited  by  the  application  of  a  Charcot  magnet.  A 
piece  of  wood  made  to  imitate  the  real  magnet  was  pre- 
pared, and  with  this  the  same  results  were  obtained  The 
patient  afterward  presented  herself  with  an  hysterical  af- 
fection of  the  elbow-joint,  which  was  also  relieved  by  the 
imitation  magnet. 

Dr.  H.  Knapp,  of  New  York,  read  a  paper  entitled 

NEURO-REHNITIS  WITH   FULMINANT  BLINDNESS. 

Case  I. — An  apparently  healthy  man,  after  a  day  of 
severe  headache  went  to  bed  and  slept  well,  but  the  fol- 
lowing morning  on  awakening  found  that  he  could  see 
with  neither  eye.  In  the  absence  of  any  other  adequate 
explanation,  the  blindness  was  attributed  to  uraemia. 
Fxamination  of  the  urine,  however,  failed  to  reveal  any 
abnormality.  The  diagnosis  of  uraemic  blindness  was 
concurred  in  by  a  number  of  prominent  physicians.  Ex- 
amination of  the  eye  showed  well-marked  choked  disks. 
The  treatment  consisted  in  the  induction  of  perspiration 
with  salicylate  of  sodium,  and  the  subsequent  use  of  iodide 
of  potassium  and  calomel.  After  the  lapse  of  some  time, 
the  islet  of  retinal  tissue  regained  its  functional  activity, 
and  the  man  could  see  objects  held  in  a  certain  position, 
provided  they  were  not  brought  too  close  to  the  eye. 
He  could  thus  read  Snellen  50,  and  could  correctly  indi- 
cate the  names  of  playing-cards.  The  doctor  thought 
that  the  attack  might  be  attributable  to  some  abnormity 
about  the  frontal  lobes  of  the  brain  in  the  region  of  the 
chiasm. 

Case  II. — A  girl  eleven  years  of  age  had  had  spells  of 
loss  of  vision  for  a  few  days,  after  which  she  awoke  one 
morning  to  find  herself  blind  in  the  left  eye.  The  right 
also  became  blind  in  the  course  of  the  same  day.  The 
urine  was  normal.  Salicylate  of  sodium  and  calomel 
were  given.  This  was  followed  by  profuse  diarrhoea. 
Two  days  later  there  was  light  perception,  and  steady  im- 
provement set  in  from  this  time.  Two  months  later  the 
eye-sight  was  completely  restored.  It  was  thought  that 
there  might  be  something  causing  pressure  in  the  neigh- 
borhood of  the  optic  chiasm  or  cavernous  plexus.  If 
there  were  such  a  condition  the  diarrhoea  which  was 
induced  would  be  of  benefit. 

Dr.  Charles  Kipp,  of  Newark,  N.  J.,  referred  to  a 
case  of  choked  disk  which  he  had  had  under  observation 
for  fifteen  years  and  in  which  no  symptoms  of  brain  or 
other  trouble  had  been  observed.  He  thought  that 
probably  in  some  instances  optic  neuritis  was  due  to 
other  than  cerebral  lesions. 

Dr.  H.  Knapp  called  attention  to  the  fact  that  disease 
of  the  frontal  lobes  might  exist  for  a  long  time  without 
producing  alarming  symptoms. 

Dr.  George  C.  Harlan,  of  Philadelphia,  stated  that 
he  had  examined  a  number  of  patients  in  blind  asylums, 
with  atrophy  of  the  optic  nerve,  without  finding  any  evi- 
dences of  serious  disease. 


l62 


THE  MEDICAL  RECORD. 


[August  9,  1884. 


Dr.  a.  Alt,  of  St.  Louis,  had  seen  a  case  of  neuro* 
retinitis  with  large  hemorrhage,  which  was  thought  to  be 
due  to  a  tumor  of  the  brain  and  with  marked  impairment 
of  the  general  health.  Under  the  use  of  iodide  of  potas- 
sium the  health  was  restored.  There  is,  however,  atro- 
phy of  both  optic  nerves. 

Dr.  W.  F,  Norris,  of  Philadelphia,  read  a  paper  on 

HEREDITARY  ATROPHY   OF  THE    OPTIC   NERVE. 

In  a  family  of  twenty-three  persons  which  had  been  ex- 
amined by  Dr.  Norris,  fourteen  were  found  to  have  con- 
genital atrophy  of  the  optic  nerve.  Bichloride  of  mer- 
cury and  strychnia  were  administered,  but  in  only  one 
case  did  improvement  ensue. 
Dr.  Norris  also  reported 

TWO   CASES   OF   ORBITAL  TUMOR. 

The  first  case  was  one  of  myxo-sarcoma  of  the  orbit  oc- 
curring in  a  child  four  months  old.  The  tumor  was 
twice  removed,  but  returned  after  both  operations.  In 
the  second  case,  the  tumor  was  an  osteoma,  which  ap- 
peared in  a  woman  thirty-two  years  of  age.  The  growth 
involved  so  much  of  the  orbit,  that  it  became  necessary 
to  remove  the  eye.  This  eye  had  been  bhnd  for  some 
time.  The  tumor  was  chiselled  away.  There  has  been 
no  return  of  the  disease. 
Dr.  J.  A.  Andrews,  of  New  York,  read  a  paper  on 

JEQUIRITY. 

He  objected  to  the  plan  usually  followed  in  the  use  of 
this  drug.  His  method  is  to  employ  a  one  per  cent, 
fresh  solution,  which  is  brushed  over  the  eye  once.  The 
eye  is  examined  after  twenty-four  hours  and  the  applica^ 
tion  repeated,  if  necessary.  In  this  way  he  has  had 
good  results  with  no  accidents. 

Dr.  Norris  had  observed  that  the  conjunctiva  seems 
to  lose  its  susceptibility  to  the  action  of  the  drug  after 
frequent  applications. 

Dr.  H.  S.  Schell  had  used  preparations  which  had 
been  preserved  for  weeks  by  the  addition  of  four  grains 
of  boracic  acid  to  each  ounce  of  the  infusion. 

Dr.  Wadsworth  had  preserved"  the  infusion  active 
and  free  from  bacilli  with  the  addition  of  two  per  cent 
of  carbolic  acid. 

Dr.  J.  S.  Prout  stated  that  he  had  used  quinine  a 
number  of  years  ago  in  the  class  of  cases  for  which 
jequirity  was  recommended.  It  had  produced  very  sat- 
isfactory results. 

Adjourned. 


Afternoon  Session. 

The  Society  again  met  at  4  p.m.,  to  examine  a  number 
of  microscopical  specimens  prepared  by  Dr.  A.  Alt,  of 
St.  Louis,  and  to  witness  the  demonstration  of  a  new 
form  of  perimeter  by  Dr.  E.  Dyer,  of  Newport. 


Evening  Session. 

The  Society  was  called  to  order  at  eight  o'clock. 
The  first  paper  was  read  by  Dr.   H.  S.  Schell,  of 
Philadelphia,  on 

EMBOLISM   of  THE   CENTRAL    ARTERY  OF  THE    RETINA. 

An  old  lady  suddenly  lost  vision  in  the  left  eye.  There 
was  found  to  be  on  examination  insufficiency  of  the  mitral 
valve  and  hypertrophy  of  the  left  ventricle.  Special  at- 
tention was  called  to  the  fact  that  after  massage  of  the 
eyeball  a  current  was  induced  in  the  vessels,  but  this 
current,  instead  of  being  continuous,  was  broken  into 
segments.     No  benefit  followed  treatment. 

Dr.  a.  Mathewson,  of  Brooklyn,  then  read  a  paper 
on 

THE   NATURAL   HISTORY   OF  CATARACT. 

A  man  who  had  suffered  from  cataract  for  some  years 
suddenly  regained  vision.    An  examination  of  the  eye 


showed  that  the  lens  had  disappeared,  and  it  was  after, 
ward  found  in  the  lower  part  of  the  vitreous.  Two  years 
later  a  severe  attack  of  glaucomatous  inflammation  re- 
quired  the  removal  of  the  eye.  The  lens  was  found  to 
be  extremely  small. 

Other  members  reported  cases  of  a  similar 'character. 

Dr.  W.  W.  Seely,  of  Cincinnati,  described  his  expe- 
riences in  certain  refractive  cases,  alluding  particularly 
to  lack  of  balance  of  the  ocular  muscle  and  its  relation 
to  refractive  changes.  He  thought  that  if  all  cases  of 
so-called  mixed  astigmatism  were  examined  after  paraly- 
sis of  the  accommodation,  many  of  them  would  be 
found  to  be  examples  of  simple  hypermetropic  astigmaf- 
tism.     A  number  of  illustrative  cases  were  cited. 

Dr.  L.  Webster  Fox  presented  a  paper  on 

THE    CLINICAL    HISTORY    OF    A     CASE     OF    SYMPATHETIC 
OPHTHALMIA. 

A  boy  received  a  punctured  wound  near  the  cornea  of 
the  left  eye.  It  was  treated  with  cold  applications  and 
little  inflammation  ensued.  Later,  however,  dimness  of 
vision  manifested  itself  in  the  right  eye.  At  this  time 
there  was  barely  light  perception  in  the  eye.  Vigorous 
treatment  was  instituted,  but  did  not  abort  the  inflamma- 
tion. Later,  iodide  of  potassium  and  mercury  were  ad- 
ministered, but  with  no  benefit.  A  recent  examination 
showed  the  right  eye  atrophied  to  half  its  normal  size, 
with  no  perception  of  light, 'and  the  left  eye,  becoming 
atrophied,  light-perception  doubtful. 

Dr.  J.  A.  LippiNCOTT,  of  Pittsburg,  Pa.,  read  a  paper 
entitled 

TWO  CASES  OF  ORBITAL  ABSCBSS. 

The  first  case  occurred  in  the  latter  part  of  1877  in  a 
child  of  feeble  powers  of  resistance,  and  the  abscess  fol- 
lowed an  attack  of  erjrsipelas  of  the  face  and  scalp.  A 
small  abscess  of  the  nght  upper  eyelid  developed,  which 
was  opened  and  a  poultice  applied.  Six  days  later  the 
eyeball  began  to  protrude  rapidly  and  the  pain  and  gen- 
eral symptoms  became  more  marked.  The  ball  pro- 
truded more  than  half  an  inch.  Diplopia  was  observed 
and  the  sight  appeared  to  be  unimpaired. 

An  exploratory  incision  was  made  under  ether,  and 
pus  being  found  a  free  incision  was  made,  allowing  the 
escape  of  a  quantity  of  pus.  It  was  decided  to  not  in- 
sert a  tent,  but  a  poultice  was  applied,  pressure  made, 
and  a  supporting  treatment  instituted.  Under  this  treat- 
ment the  patient  improved,  and  the  protrusion  became 
less  marked.  Two  days  after  the  operation  on  the  right 
eye  it  became  necessary  to  open  an  abscess  behind  the 
left  ball  This  rapidly  healed  without  further  treatment. 
An  examination  made  a  short  time  ago  showed  very 
slight  protrusion  of  the  right  eye.     V  =  JJ. 

Case  II. — A.  R ,  scarcely  twelve  months  old,  was 

seen  in  the  latter  part  of  1880.  Swelling  and  chemosis 
of  the  lids  had  appeared  three  weeks  previously.  There 
was  no  protrusion  of  the  ball  until  a  few  days  before  she 
was  seen  by  Dr.  Lippincott.  At  that  time  the  ball  pro- 
truded to  the  extent  of  its  diameter,  the  pupil  was  of 
natural  size  and  irresponsive.  The  pain  did  not  seem  to 
be  severe  and  there  was  only  slight  fever. 

An  aspirating  needle  was  introduced  above  the  globe 
and  an  abscess  containing  fetid  pus  was  found ;  this  was 
evacuated  and  a  poultice  applied  Improvement  of  the 
general  condition  at  once  began,  but  one  week  later  the 
opening  closed,  and  as  there  evidently  was  pus  still  be- 
hind the  globe,  a  second  opening  was  made,  and  at  this 
time  healthy  pus  escaped.  Pus  continued  to  flow  for 
two  weeks  when  the  opening  closed.  The  child  coi> 
tinned  to  improve,  and  a  recent  examination  showed; 
very  little  protrusion  of  the  ball,  considerable  swelling;; 
of  the  lids,  and  partial  ptosis.  The  eyeball  is  fireelf 
movable.  The  disk  shows  decided  white  atrophy,  and 
the  vessels  of  the  retina  are  contracted.  Vision  is  lim-: 
ited  to  light-perception. 

Dr.  Samuel  Theobald,  of  Baltimore,  described  aj 
case  of  this  nature,  which  he  had  recently  seen  occurring 


August  9,  1884.] 


THE  MEDICAL  RECORD. 


163 


jo  a  roan  run  down  from  over-work.  Four  days  after 
the  beginning  of  the  symptoms  deep  fluctuation  was  felt, 
and  the  abscess  was  opened.  Poultices  were  then  ap- 
pb'ed  Two  dfays  later  it  was  found  necessary  to  evacu- 
ate a  collection  of  pus  which  had  formed  beneath  the 
ball  Perfect  recovery  followed,  the  vision  being  re- 
stored, and  the  mobility  being  normal. 
•    Bk.  Charles  J.  Kipp,  of  Newark,  read  a  paper  on 

ABSCISS  OF  THE    FRONTAL   SINUS,    ETHMOID    CELLS,  AND 
SPHENOIDAL   SINUS. 

J.  B ,  aged  fifty-four,  had  suffered  for  many  years 

from  headache.  The  left  eye  was  slightly  protruding, 
and  a  tumor  was  seen  involving  the  upper  part  of  the 
orbit.  Sarcoma  was  diagnosed,  but  a  few  days  later,  in 
attempting  to  remove  it,  the  swelling  broke^  and  a  large 
qoaotity  of  pus  escaped.  A  drainage-tube  was  intro* 
duced.  Shortly  after  the  operation  the  patient  had  pneu- 
monia, from  which  he  died.  After  death  it  was  found 
that  the  frontal  sinus,  the  ethmoidal  cells,  and  sphenoidal 
sinus  had  been  converted  into  one  large  pus  cavity,  from 
the  walls  of  which  numerous  spicules  of  bone  projected. 

Dr.  Kipp  also  reported  a  case  of  distention  of  the 
frontal  sinus.  A  woman,  aged  fifty-seven,  presented  a 
painful  tumor  below  the  left  eyebrow.  She  had  suffered 
from  nasopharyngeal  catarrh  for  a  number  of  years.  On 
pressure,  fluctuation  could  be  discovered.  An  opera- 
tion was  declined.  The  case  was  seen  one  year  later,  at 
which  time  the  sac  accidentally  ruptured,  and  the  con- 
tents escaped  into  the  nose.  The  cyst  continued  to 
refill  for  some  time,  but  after  some  months  the  discharge 
diminished,  and  at  the  present  time  the  sac  seldom  be- 
comes distended.  The  treatment  consisted  in  the  appli- 
cation of  nitrate  of  silver  solution  to  the  mucous  mem- 
brane of  the  naso-pharynx,  the  frequent  washing-out  of 
the  nasal  cavity,  and  the  emptying  of  the  distended 
frontal  sinus  by  pressure  made  with  the  flnger. 
Dr.  L.  Howe,  of  Buffalo,  read  a  paper  entitled, 

CHANGES  IN  THE   EYE   IBIMEDIATELY  AFTER   DEATH. 

The  observations  were  made  on  a  man,  aged  flfty-four, 
dying  of  consumption.  One  of  the  conditions  noticed 
was  a  wrinkling  of  the  cornea,  which  it  was  said  might 
readily  be  mistaken  for  fracture  rupture  of  the  lens.  He 
had  also  seen  the  same  condition  after  hanging. 

Dr.  NoRRib  asked  whether  any  rose-colored  macula 
bad  been  observed  after  death  by  hanging.  These  had 
been  observed  in  the  case  of  beheaded  criminals. 

Dr.  Howe  had  observed  none. 

Dr.  MriTENDORF  called  attention  to  the  fact  that  Dr. 
Derby  had  made  a  report  some  time  ago  in  reference  to 
the  condition  of  the  eyes  after  hanging.  In  six  eyes  ex- 
amined, m  five  dislocation  of  the  lens  had  been  observed. 

Adjourned. 


Second  Day — Thursday,  July  17TH — Morning 
Session. 

case  of  glioma  of  the  retina. 

Dr.  Theobald  reported  a  case  of  glioma  in  which  he 
enodeated  the  eye  four  years  ago.  The  patient  is  still 
onder  observation  and  there  has  been  no  return  of  the 
&ease.  In  another  case  he  had  performed  the  opera- 
tion. Twelve  months  later  the  patient  died  from  some 
oiiscure  disease  of  the  brain.  There  had  been  no  return 
<tf  the  glioma.  The  age  of  the  first  case  was  twelve 
jears,  that  of  the  second  nine  years. 

Dr.  Mittendorf  asked  if  any  of  the  members  had 
Ken  a  case  of  glioma  in  which  the  patient  did  not  die 
iftcr  operation.  Although  the  operation  prolongs  life, 
k  thoQght  that  it  did  not  save  it.  It  was  unusual  for 
k  dis^ise  to  develop  as  late  as  in  the  cases  reported  by 
Dr.  Theobald. 

,  Dr.  Sutphen,  of  Newark,  reported  a  case  of  glioma 
i&a  child  nine  years  of  age.  Enucleation  was  advised, 
tnt  declined.     Five  months  later  the  child  was  brought 


suffering  with  choreic  symptoms.  Thinking  that  the 
chorea  was  due  to  the  eye  trouble  it  was  enucleated. 
The  child  recovered  while  taking  Fowler's  solution. 

Dr.  Mathewson  thought  that  some  of  the  rare  cases 
in  which  the  disease  had  not  returned  after  operation 
might  be  accounted  for  by  a  mistake  in  the  diagnosis. 

Dr.  Knapp  said  that  there  could  be  no  doubt  of  per- 
manent recovery  occurring  after  true  glioma.  These 
cases  are,  however,  rare.  In  his  own  experience  he  had 
had  but  one  case.  This  had  been  under  observation  for 
fourteen  years. 

Dr.  William  Thompson,  of  Philadelphia,  made  a 
partial  report  of  the  progress  of  the  examination  of  the 
employees  of  the  Pennsylvania  Railroad  as  to  their  color- 
sense  and  acuteness  of  vision  and  hearing.  He  also 
considered  the  importance  of  national  legislation  on  this 
subject,  and  described  what  had  already  been  done  in 
this  direction. 

Dr.  George  C.  Harlan  reported 

TWO  cases  of  swelling  of  the  optic  papule,  prob- 
ably CONGENITAL. 

The  first  case  was  that  of  a  short-sighted  student,  who 
consulted  Dr.  Harlan  in  reference  to  glasses  that  he  was 
wearing.  An  ophthalmoscopic  examination  which  was 
then  made  showed  that  there  was  swelling  of  the  optic 
papule  to  the  extent  of  3  or  4  D.  He  was  advised  to 
be  cautious  in  the  use  of  the  eyes.  The  case  was  seen 
subsequently,  but  no  change  was  noted. 

The  second  case  was  that  of  a  girl  aged  fifteen  years. 
She  complained  of  pain  in  the  eyeball,  increased  by  use, 
and  occasional  double  vision  in  a  vertical  direction. 
There  was  hypermetropia,  and  also  swelling  of  the 
optic  papule.  Weak  convex,  slightly  smoked  glasses 
were  given.  With  this  the  vision  was  j^t-  A  tonic  treat- 
ment was  instituted.  The  patient  sood  afterward  passed 
from  observation,  and  has  not  been  seen  since. 

Dr.  Risley  reported  the  case  of  a  young  married 
woman  who  consulted  him  for  asthenopic  symptoms. 
There  was  found  to  be  hypermetropic  astigmatism  and 
swelling  of  the  nerve  to  the  extent  of  two  or  three  diop- 
trics. The  condition  was  the  same  in  both  eyes.  There 
had  been  no  dizziness  and  no  more  headache  than  could 
be  accounted  for  by  the  eye-strain.  There  was  nothing 
abnormal  about  the  urine.  The  proper  glasses  being 
given  the  symptoms  disappeared,  and  a  year  later  had 
not  returned.  There  had  at  this  time  been  no  change 
in  the  appearance  of  the  eye. 

Dr.  Mittendorf  also  reported  a  case  of  hypermetropic 
astigmatism  with  a  similar  condition  of  the  nerve.  He 
attributed  this  appearance  to  an  abnormal  development 
of  the  connective  tissue  elements  of  the  optic  disk. 
This  view  was  held  on  account  of  the  silky  appearance 
of  the  retina.  This  case  had  been  under  observation 
for  over  a  year. 

Dr.  G.  Hay,  of  Boston,  reported 

TWO  cases   in  which  rahlman's  hyperbolic  lenses 

IMPROVED  VISION. 

The  first  case  was  that  of  a  lawyer,  in  whom  the  cor- 
nea  was  decidedly  prominent.  Vision  was  improved  by 
a  cylindrical  glass,  but  it  was  made  still  better  with 
hyperbolic  lenses. 

The  second  case  was  one  of  pronounced  conical  cor- 
nea.    In  this  case  also  vision  was  much  improved. 

Dr.  O.  F.  Wadsworth,  of  Boston,  read  a  paper  on 

MYXODERMA,  with  atrophy  of  the  optic  NERVES. 

The  patient  was  a  married  woman,  forty-two  years  of 
age.  There  was  no  history  of  syphilis.  Menstruation 
had  been  regular  until  three  years  ago,  when  it  ceased. 
Six  years  ago  it  was  noticed  that  the  lower  part  of  the 
face,  the  hands,  and  the  feet  became  full  and  oedema- 
tous,  but  did  not  pit  on  pressure.  This  condition  in- 
creased. At  the  present  time  the  hands  and  feet  are 
very  much  enlarged.     The  lower  part  of  the  face  and. 


i64 


THE  MEDICAL  RECORD. 


[August  9,  1884. 


what  is  unusual,  the  nose  is  much  enlarged.  The  lips 
are  thick  and  the  speech  is  slow,  as  though  the  tongue 
were  enlarged.  The  skin  is  not  particularly  dry,  but  she 
never  sweats.  Her  mental  condition  is  good,  although 
her  husband  thinks  that  her  memory  is  not  as  good  as 
formerly. 

The  affection  of  vision  was  first  noticed  in  the  right 
eye  a  year  and  a  half  ago.  This  gradually  increased 
until  there  was  only  light  perception.  In  the  left  eye 
vision  was  xl.  The  field  was  contracted  upward  and 
outward.  The  optic  disks,  especially  that  of  the  right 
eye  showed  the  appearances  of  simple  gray  atrophy.  No 
apparent  cause  could  be  discovered  for  this  condition. 
The  fact  that  the  atrophy  appeared  in  the  course  of  the 
myxoderma  did  not  prove  that  there  was  any  connection 
between  the  two,  but  considering  that  our  knowledge  of 
the  cause  and  pathology  of  myxoderma  is  so  incomplete 
he  thought  it  well  to  place  this  case  on  record.  He  had 
examined  other  cases  of  myxoderma,  but  this  was  the  only 
one  in  which  any  alteration  of  vision  had  been  observed. 

Dr.  Little  had  also  examined  the  eyes  of  those  suffer- 
ing with  this  affection,  but  had  been  unable  to  find  any- 
thing abnormal. 

Dr.  Thomas  R.  Pooley,  of  New  York,  read  a  paper 
entitled 

ACUTE   DACRYO-ADENITIS, 

A  girl,  twenty  years  of  age,  who  for  some  time  had  been 
suffering  with  chronic  trachoma  and  trichiasis,  was  seized 
with  diphtheritic  inflammation  of  the  conjunctiva  of  the 
left  eye.  This  caused  the  complete  destruction  of  'the 
eye.  Three  weeks  later,  when  the  purulent  discharge  was 
beginning  to  abate,  pain  began  to  be  felt  in  the  right  eye 
and  a  swelling  made  its  appearance  at  the  upper  outer 
angle.  This  was  tense  and  red.  Hot  applications  were 
ordered  and  she  was  put  on  the  use  of  quinine  and  iron. 
The  following  day  an  incision  was  made  through  the  lid, 
but  no  pus  was  obtained.  The  following  day  there  was 
marked  improvement.  The  hot  applications  were  con- 
tinued and  a  pressure*bandage  applied.  She  made  a 
rapid  recovery,  and  now  vision  is  entirely  restored.  It 
was  thought  that  probably  the  inflammation  of  the  lachry- 
mal gland  was  due  to  septic  absorption. 

Dr.  H.  Knapp,  in  speaking  of  the  differential  diagnosis, 
said  that  the  diagnosis  could  be  made  by  pressing  deeply 
into  the  orbit.  It  would  then  be  found  that  the  swelling 
was  limited  to  the  gland,  and  that  it  gave  a  nodular  sen- 
sation, some  of  the  nodules  being  harder  than  others.  It 
is  not  very  rare  to  have  inflammation  of  one  lachrymal 
gland,  but  it  is  rare  to  have  the  inflammation  appearing 
in  both  glands  within  one  or  two  days.  In  the  cases 
which  he  had  seen  there  had  been  no  infectious  disease, 
and  in  the  majority  no  conjunctival  trouble. 

Dr.  Miller,  of  Providence,  stated  that  he  had  had 
one  case  of  acute  bilateral  inflammation  of  the  lachrymal 
gland.  The  patient  was  suffering  with  gonorrhoea  at  the 
time  and  his  physician  regarded  it  as  a  case  of  gonorrhoeal 
ophthalmia.  The  inflammation  subsided  in  the  course  of 
a  few  days  under  the  use  of  hot  applications. 

Dr.  W.  F.  Mittendorf,  of  New  York,  read  a  paper  on 

POLYCORIA. 

The  patient.  Miss  R ^  sought  advice  for  some  ab- 
normity of  vision.  Seven  years  previously  the  right 
eye  had  been  lost.  There  was  compound  myopic  astig- 
matism in  the  left  eye.  On  examining  it  five  pupils  were 
found.  With  suitable  glass  V.  =  JJ,  and  the  range  of 
accommodation  was  good. 

The  father  of  this  lady  also  had  a  similar  defect  in  the 
iris.  In  the  right  eye  there  were  two  pupils,  the  lower 
of  which  was  divided  into  two  by  a  band  passing  across  it. 

Dr.  W.  W.  Seely,  had  examined  a  family  in  which  a 
number  of  its  members  had  polycoria.  The  interesting 
point  was  the  termination,  all  these  persons  becoming 
blind. 

Dr.  Mittendorf  stated  that  his  patients  were  aged 


thirty-two  years  and  sixty-flve  years,  and  that  neither  had 
exhibited  any  indication  of  failing  sight. 
Dr.  E.  Hxn'CHiNSON,  of  Utica,  described 

A  plastic  operation    performed    to    relieve  the 

CLOSURE   OP    THE    LIDS,   THE    RESULT    OF    CICATRIZA- 
TION. 

The  man  had  his  face  injured  by  the  premature  cxplo- ' 
sion  of  a  blast.  This  caused  destruction  of  the  left  eye, 
and  such  contraction  of  the  lids  of  the  right  eye  that  it 
was  impossible  for  him  to  open  them.  The  sight  of  the 
right  eye  was  uninjured.  The  operation  consisted  in 
cutting  deeply  through  the  external  commissure,  then  dis- 
secting up  a  web  of  conjunctiva  which  was  put  into  this 
opening  and  secured  there.  After  he  had  recovered  from 
this  operation  there  was  great  ectropion,  which  was  re- 
lieved by  making  a  deep  V-shaped  incision  and  free  dis- 
section and  bringing  the  parts  together.  The  lid  was 
thus  restored  and  a  very  satisfactory  result  obtained. 

Dr.  J.  AuB,  of  Cincinnati,  read  a  paper  on 

REMOVAL  OF  FOREIGN   BODIES   FROM   THE  VITREOUS. 

He  reported  three  cases  in  which  pieces  of  iron  had 
entered  the  vitreous  humor.  In  all  of  these  the  piece  of 
iron  was  removed  by  means  of  an  electro-magnet  passed 
into  the  eye.  In  these  cases  the  eye  and  the  sight  were 
saved. 

A  fourth  case  was  reported  in  which  the  piece  of  iron 
had  become  encysted  and  could  not  be  removed  with  the 
magnet.  In  this  case  it  became  necessary  to  enucleate 
the  ball,  and  after  the  removal  of  the  eye  it  was  found 
impossible  to  remove  the  foreign  body  with  forceps  be- 
fore cutting  the  lymph  which  surrounded  it. 

Dr.  Knapp  said  that  where  a  foreign  body  can  be 
seen,  it  is  usually  not  a  difficult  matter  to  remove  it,  the 
question  was  as  regards  those  cases  in  which  it  passes 
out  of  sight.  He  had  in  one  case  succeeded  in  removing 
the  foreign  body.  He  felt  inclined  to  say,  judging  from 
his  own  experience  and  the  recorded  experience  of  othen, 
that  those  cases  in  which  the  foreign  body  enters  the  eye 
and  passes  out  of  sight,  the  best  thing  to  do  would  be  to 
enucleate  the  eye.  In  this  way  he  thought  that  the  great- 
est good  would  be  done  to  the  greatest  number. 

Dr.  Mittendorf,  agreed  in  this  opinion. 

HYPERMETROPIC  ASTIGMATISM   PASSING   INTO  MYOPIA, 

was  the  title  of  a  paper  by  Dr.  S.  D.  Risley,  of  Phila- 
delphia. In  1875,  ^^  ^^^  ^^^  ^  child  suffering  from 
violent  headache.  There  was  hypermetropic  astigmatism. 
The  ophthalmoscope  revealed  the  usual  appearances  of 
choroidal  and  retinal  irritation.  With  a  suitable  cylin- 
dro-spherical  glass  vision  was  normal.  This  entirely 
relieved  the  symptoms.  The  patient  passed  from  obser- 
vation and  was  not  seen  until  1882.  At  this  time  there 
was  found  to  be  myopic  astigmatism.  The  proper  glasses 
being  given,  the  symptoms  from  which  she  had  suffered 
disappeared  and  vision  was  again  made  normal. 

Dr.  Knapp  thought  that  many  of  the  cases  of  astigma- 
tism in  young  girls  of  nervous  temperament  were  not 
real  deformities  of  the  cornea,  but  that  they  would  dis- 
appear under  proper  hygienic  surroundings.  He  thought 
that  slight  degrees  of  error  might  be  overlooked. 

Dr.  Theobald  said  that  the  indication  for  correction 
in  slight  degrees  of  myopia  was  the  presence  of  asthen- 
opic  symptoms,  which  are  sometimes  due  to  disproportion 
between  accommodation  and  convergence.  In  slight  de- 
grees of  myopia,  where  there  is  no  asthenopia  there  is  no 
discomfort,  and  correction  may  not  be  necessary. 

The  Society  then  went  into  executive  session. 

The  following  officers  were  elected  :  President — Dr. 
W.  F.  Norris,  Philadelphia  ;  Vtce- President— Dr.  Hasket 
Derby,  New  York  ;  /Recording  Secretary  and  Treasurer 
—Dr.  O.  F.  Wadsworth,  Boston ;  Corresponding  Secre- 
tary—T>x.  J.  S.  Prout,  Brooklyn  ;  Committee  on  Puhlica- 
tion — Drs.  O.  F.  Wadsworth,  Hasket  Derby,  and  G. 
Hay  ;  Committee  on  Membership — Drs.  John  Green,  G. 


August  9. 1884.] 


THE  MEDICAL  RECORD. 


165 


C.  Harlan,  A*  Mathewson,  S.  Theobald,  and  J.  J.  B. 
Vennync. 

The  following  were  elected  to  membership  :  Dr.  Miles 
Standish,  of  Boston,  Mass.;  Dr.  John  Van  Duyn,  of 
Sfiacuse,  N.  Y.,  and  Dr.  S.  O.  Richey,  of  Washington, 

D.C. 

The  place  for  holding  the  meetmg  of  next  year  was 
•  not  decided  on,  but  its  selection  left  to  the  secretary. 
Tlic  time  of  meeting  is  the  third  Wednesday  of  July. 

The  Society  then  adjourned. 


THE  SURGICAL  SOCIETY  OF  PARIS. 

Stated  Meetings  June  4,  1884. 
M.  Marcus  S^e,  President,  in  the  Chair. 

(Special  Report  to  Thb  Mbdical  Record.) 

AfTER  the  Society  had  been  called  to  order,  the  report 
was  read  of  the  committee  for  the  organization  of  an 

ANNUAL  CONGRESS   OF   FRENCH   SURGEONS. 

This  report  gave  rise  to  a  lengthy  discussion. 
M.  BoECKEL  then  read  the  history  of  a  case  operated 
upon  by  himself  for  the 

REMOVAL  OF   THE   ENTIRE   UTERUS   PER   VAGINAM 

OD  account  of  cancer  of  the  cervix.  The  operation  was 
undertaken  in  October,  1882.  After  pushing  the  uterus 
as  far  down  as  possible,  the  posterior  cul-de-sac  was 
divided  by  a  transverse  incision,  and  the  anterior  part 
dissected  away,  so  as  to  leave  the  organ  attached  only 
bj  the  broad  Ifgaments.  A  double  ligature  being  placed 
on  each,  the  ligaments  were  then  divided.  In  the  left 
broad  ligament  M.  Boeckel  found  an  enlarged  and  de- 
generated gland,  which  he  excised.  This  was  followed 
by  a  free  hemorrhage,  which  was  arrested  by  haemostatic 
forceps  applied  somewhat  at  random  and  left  in  situ. 
As  the  intestines  showed  no  tendency  to  come  out 
through  the  wound,  no  sutures  were  passed  through  the 
peritoneum.  The  vagina  was  tamponed  with  cotton 
dusted  with  iodoform. 

The  patient  seemed  to  be  making  a  good  recovery, 
mtii  it  was  found  that  the  urine  was  constantly  passing 
iway  from  a  wound  made  in  the  left  ureter  by  the 
luemostatic  forceps.  The  only  remedy  for  this  condition 
seemed  to  be 

NEPHRECTOMY, 

which  was  accordingly  performed.  The  patient  re- 
corered  promptly,  and  was  discharged  cured  two  weeks 
after  the  last  operation.  Seven  months  later,  however, 
she  died  from  cancerous  infiltration  of  the  vaginal  walls 
and  the  neighboring  glands. 

From  a  study  of  this  case  M.  Boeckel  concluded  that : 
fiist,  the  antiseptic  method  renders  justifiable  the  under- 
taking of  very  serious  operations  ;  and,  second,  the  total 
txtirpation  of  the  uterus  should  be  considered  an  excep- 
tkmal  operation,  to  be  undertaken  only  when  the  cancer- 
oas  infiltration  is  localized. 

M.  Verneuil  agreed  with  the  author  that  hysterec- 
tomy ought  to  be  undertaken  only  in  exceptional  cases. 
He  thought  that  the  treatment  of  carcinoma  of  the  uterus 
bjr  cauterization  and  local  applications  gave  the  best 
diance  to  the  patient. 

M.  Terrier  had  recently  performed  this  operation, 
aod  spoke  of  the  difficulties  attending  it.  One  of  the 
greatest  of  these  is  met  with  in  pulling  down  the  broad 
ligaments,  so  as  to  permit  the  application  of  the  liga- 
tures. 

M.  PoLAiLLON  did  not  agree  with  the  author  of  the 
paper  regarding  the  indications  lor  the  operation.  He 
would  operate  only  in  those  cases  in  which  the  entire 
Qtgaa,  and  not  the  cervix  alone  is  involved  in  the  can- 
cerous process.  But  if  the  new  growth  has  advanced 
veiy  £ar  no  operation  is  of  any  avail. 


M.  Lucas-Championni£rs  had  seen  Billroth  perform 
the  operation  in  a  case  in  which  one  of  the  broad  liga- 
ments was  involved  in  the  carcinomatous  degeneration, 
and  was  surprised  at  the  ease  with  which  the  removal 
of  the  organ  was  accomplished.  The  main  difficulty  he 
thought  was  one  of  diagnosis. 

M.  Terrier  did  not  agree  with  M.  Polaillon,  but  ad- 
vocated the  removal  of  the  entire  uterus.  He  thought 
that  the  attempt  to  destroy  the  new  growth  by  the  gal- 
vano-cautery  and  chloride  of  zinc  was  not  unattended 
with  danger. 

M.  Tri£lat  did  not  think  the  results  obtained  in  the 
past  seven  years  by  extirpation  of  the  uterus  were  such 
as  to  offer  much  encouragement.  He  himself  had  never 
had  the  courage  to  attempt  it.  Indeed,  he  thought  there 
was  little  to  hope  for  in  any  operation,  as  by  the  time 
that  the  patient  fell  into  the  surgeon's  hands  the  disease 
was  usually  very  extensive. 

M.  BouiLLY  was  convinced,  from  experiments  made 
upon  the  cadaver,  that  it  was  often  impossible  to  depress 
the  uterus  sufficiently  to  render  the  vaginal  operation 
practicable. 

M.  Polaillon  stated,  in  support  of  his  opinions,  that 
the  mortality  in  total  extirpation  of  the  uterus  was  one  in 
three,  while  that  from  removal  of  the  cervix  was  three  in 
twenty.  He  had  had  two  cases  of  removal  of  the  new 
growth  by  the  galvano-cautery  and  chloride  of  zinc,  in 
which  there  was  no  return  of  the  disease  after  five  years. 
Another  patient,  seventy-two  years  of  age,  operated  upon 
by  the  same  method,  had  rtsmained  well  for  one  year. 

M.  Boeckel  then  exhibited  a  patient,  seventeen  years 
old,  upon  whom  he  had  performed 

osteotomy  by  macewen's  method 

for  knock-knee.  He  had  performed  upward  of  twenty 
osteotomies  and  nearly  as  many  osteoclasies.  The  re- 
sults of  osteotomy  were  uniformly  good,  but  he  had  met 
with  three  accidents  in  his  osteoclasies.  In  one  case  he 
had  ruptured  the  external  lateral  ligament ;  in  another,  a 
suppurative  periostitis  had  been  excited  which  required 
four  months  to  cure ;  and  in  the  third  case  there  remained 
an  incurable  pseudarthrosis. 
The  Society  then  adjourned. 


Stated  Meeting,  June  11,  1884. 
The  Society  having  been  called  to  order,  the 

discussion  on  vaginal  hysterectomy 
was  resumed 

M.  Verneuil  stated  that  he  had  performed  ablation  of 
the  cervix  twenty  times,  twice  for  hypertrophy  of  the 
anterior  lip,  once  for  sclerosing  metritis,  which  he  had 
mistaken  for  an  epithelioma,  and  seventeen  times  for 
cancer.  Of  the  latter  cases  one  had  died  and  two  had 
been  lost  sight  of  after  three  years  had  elapsed  without 
return  of  the  disease.  Of  the  remainder  *  the  average 
duration  of  life  after  the  operation  was  nineteen  months. 
The  speaker  did  not  condemn  the  total  extirpation  of 
the  uterus,  but  he  considered  that  the  existence  of  a 
limited  epithelioma  of  the  cervix  was  not  a  sufficient 
indication  for  the  operation. 

M.  Despr^s  had  removed  the  cervix  seven  times, 
three  times  for  hypertrophy  of  the  anterior  lip,  and  four 
times  for  cancer.  He  did  not  think  that  an  operation 
was  of  much  value  in  prolonging  life,  for  the  average 
duration  of  life  in  those  not  operated  upon  was  eighteen 
months.  When  the  general  condition  was  bad,  life  was 
prolonged  not  one  hour  by  the  removal  of  the  new 
growth. 

M.  Tr^lat  was  surprised  that  M.  Verneuil  should  have 
had  so  many  opportunities  to  practise  amputation  of  the 
cervix,  since  the  patients  usually  present  themselves  to 
the  surgeon  only  after  the  disease  has  progressed  too  far 
to  render  this  operation  of  any  avaal.  He  was  in  accord 
with  that  gentleman  in  respect  to  the  methods  of  tceat- 


166 


THE  MEDICAL  RECORD. 


[August  9,  1884 


ment  employed,  and  he  believed  that  these  methods 
were  the  best  adapted  for  prolonging  life.  He  had  seen 
patients  gain  flesh  and  be  restored  to  apparent  health 
under  this  treatment  of  the  local  affection. 

M.  Berger  then  made  a  report  upon  a  memoir  sub- 
mitted by  M.  Kirmisson  entitled 

INGUINAL  ANEURISMS. 

The  author  stated  that  the  appearance  of  an  aneurism  in 
the  groin  is  often  preceded  by  an  abscess  or  enlargement 
of  the  inguinal  glands.  Malgaigne  and  others  had  al- 
ready noted  this  fact.  As  regards  the  treatment,  M. 
Kirmisson  expressed  a  decided  preference  for 

LIGATURE   OF  THE   EXTERNAL   ILIAC   ARTERY 

over  either  mechanical  or  digital  compression.  Of  the 
four  methods  at  present  in  vogue  he  would  retain  two, 
those  of  Sir  Astley  Cooper  and  Marcellin  Duval.  The 
procedures  introduced  by  Bogros  and  Abernethy  he 
looked  upon  as  dangerous.  The  author  did  not  regard 
the  wounding  of  the  peritoneum  as  a  serious  complica- 
tion, but  on  this  point  M.  Berger  differed  from  him  very 
decidedly,  and  he  insisted  upon  the  necessity  of  laying 
aside  the  bistoury  as  soon  as  the  aponeurosis  of  the  obli- 
quus  externus  had  been  divided.  Secondary  hemor- 
rhage, when  it  occurred,  was  to  be  attributed,  M.  Berger 
thought,  to  non-uion  of  the  wound  and  to  suppuration. 

M.  Verneuil  did  not  agree  with  M.  Berger  as  to  the 
cause  of  secondary  hemorrhage.  It  was  due,  he  be- 
lieved, to  septicaemia.  When  there  was  no  fever  there 
was  no  cause  to  anticipate  hemorrhage. 

M.  DsPRis,  while  believing  with  M.  Verneuil  that 
septicaemia  was  a  common  cause  of  secondary  hemor- 
rhage, thought  that  the  accident  was  not  less  frequently 
due  to  mechanical  causes. 

M.  Farabceuf  showed  the  excellence  of  Cooper's 
operation,  by  which  the  artery  is  reached  most  surely 
and  by  the  shortest  path.  He  agreed  with  M.  Berger 
that  no  cutting  instrument  should  be  used  after  the  di- 
vision of  the  aponeurosis  of  the  external  oblique  muscle 
had  been  accomplished. 

M.  Terrier  related  a  case  of 

extirpation  of  the^spleen, 

and  exhibited  the  organ  removed,  which  weighed  a  little 
over  thirteen  pounds.  The  patient  was  suffering  from 
a  slight  degree  of  leucocythaemia,  the  examination  of 
the  blood  showing  a  proportion  of  one  white  to  two 
hundred  and  seventy-five  red  globules.  The  operation 
was  successfully  completed,  but  the  patient  died  twentv 
hours  afterward  from  capillary  hemorrhage  into  the  peri- 
toneal cavity.  The  result  in  this  case,  the  speaker 
thought,  lends  confirmation  to  the  views  of  those  who 
refuse  to  perform  any  operation  upon  the  subjects  of 
leucocythaemia.  Such  operations  are  nearly  always  fatal, 
though  an  Italian  surgeon  has  reported  one  successful 
case  in  which  the  proportion  of  white  to  red  corpuscles 
was  as  one  to  thirty. 

The  Society  then  adjourned. 


^ovtzapan&encR. 


The  Question  of  Tying  the  Umbilical  Cord  af- 
TER  Labor.— Dr.  John  T.  Booth,  of  Wyoming,  O.,  relates 
the  history  of  a  case  where  an  illegitimate  child  was  bom 
and  the  cord  was  cut  but  not  tied.  The  probable  object 
was  to  let  the  child  bleed  to  death.  Instead  of  this  it 
did  well,  there  being  no  hemorrhage  at  all.  Dr.  Booth 
raises  the  old  query  whether  tying  the  cord  is  necessary. 
Some  have  claimed  that  it  is  not,  and  undoubtedly  in 
many,  if  not  in  most  cases,  there  will  be  no  hemorrhage 
if  the  physician  wait  till  the  child  has  breathed  a  few 
times.  But  the  present  practice  of  tying  is  a  safe  and 
wise  one. 


OUR   LONDON    LETTER. 

(From  our  Special  Correspondent)] 

THE  MEDICAL  BILL  AND  ITS  CHANCES — ^THE  COLLEGES 
—OBSTRUCTION  AT  THE  COLLEGE  OF  SURGEONS— THE 
RECENT  DISAGREEMENT  AT  THE  COLLEGE  OF  PHYSI- 
CIANS. 

I^NDON,  July  19,  1884. 

The  present  aspect  of  medical  affairs  is  far  from  reassur- 
ing. I  am  afraid,  if  your  readers  were  to  give  an  impar- 
tial opinion  on  what  may  be  termed  medical  politics  here, 
it  would  be  very  far  from  complimentary  to  the  powers 
that  be. 

The  Government  Medical  bill  is  very  likely  not  to 
pass,  and  few  tears  will  be  shed  over  it  should  it  fail. 
There  is  scarcely  any  chance  of  its  passing  except  in  an 
emasculated  and  mutilated  condition,  and  I  believe  the 
general  opinion  of  the  profession  is  that  sooner  than  pass 
such  a  bill  we  had  better  go  on  as  before.  It  is  feared 
that  the  Government  will  accept  Sir  Lyon  Playfair's 
amendment,  which  virtually  neutralizes  any  good  the 
measure  may  effect,  by  allowing  the  twenty  licensing 
bodies  to  go  on  as  before.  Many  people  imagine  this 
gentleman  to  be  a  medical  man,  as  he  was  formerly  termed 
Dr.  Playfair.  The  doctorate  was  a  German  Ph.D.,  and 
its  owner  has  no  claim  to  represent  the  profession,  al- 
though at  the  last  general  election  Dr.  Playfair  so  adroitly 
used  his  title  as  to  make  many  of  his  constituents  think 
he  was  really  a  medical  man. 

What  are  the  colleges  about  ?  Nothing*  creditable.  At 
the  Surgical  College  the  obstructives  continue  in  power. 
They  form  a  nice  little  family  party,  and  when  examiner- 
ships  fall  vacant  elect  one  another  to  them,  and  draw 
nice  salaries.  The  Senior  Vice-President,  Mr.  Savory, 
has  received  ;^9,ooo  as  fees  for  acting  as  exam- 
iner for  a  long  series  of  years — about  twenty,  I  think. 
He  is  one  of  the  most  unpopular  examiners  the  college 
ever  had,  and  is  reputed — ^justly  or  unjustly — to  delight 
in  plucking.  He  is  not  ungentlemanly ;  he  often  smiles 
blandly  on  his  victims,  and  the  worse  their  ignorance  the 
more  pleased  Mr.  Savory  seems.  The  only  faint  hope  of 
reform  lies  in  the  fact  that  the  Council  have  carried  Mr. 
Heath's  motion  to  "  consider  the  mode  of  electing  the 
president,  and  any  alterations  suggested  in  the  method 
of  proceeding  in  the  election"  in  November  next 
Meanwhile,  to  break  the  old  vicious  rule  of  going  by 
seniority,  Mr.  Holmes,  the  Junior  Vice-President,  de- 
clares that  when  it  comes  to  his  turn  he  will  decline  the 
presidency.  We  hope  Mr.  Holmes  will  have  the  courage 
of  his  convictions.  If  he  has,  he  will  acquire  more  re- 
pute as  a  reformer  than  he  has  ever  done  either  as  a 
teacher  or  an  examiner. 

Meanwhile  the  sister  college  has  been  rioting  with 
closed  doors.  The  proceedings  of  the  Fellows  have  been 
declared  to  be  secreta  collegii^  so  they  do  not  appear  in 
the  medical  journals.  What  really  occurred  is  no  secret, 
although  the  most  important  part  of  the  affair  has  not 
as  yet  been  discussed  in  print.  Some  weeks  ago,  at 
a  meeting  of  Fellows,  the  usual  list  prepared  by  the  Coun- 
cil of  proposed  new  Fellows  was  submitted  to  the  Fel- 
lows present,  and — unheard-of  insolence — ^rejected  by 
them.  Why  ?  The  real  grievance  is  that,  of  those  pro- 
posed by  the  Council,  almost  all  of  them  are  not  practis- 
ing purely  as  physicians  at  all,  although,  of  course,  they 
all  possess  the  M.R.C.P.  The  objectors,  in  fact,  de- 
scribed them  as  general  practitioners.  Another  wound 
was  the  fact  that  the  list  did  not  comprise  a  single  Uni- 
versity man.  I  must  explain  that  by  a  "University 
man  "  the  older  members  of  the  profession  mean  a  grad- 
uate of  Oxford  or  Cambridge.  In  times  past  these  alone 
were  eligible  for  the  Fellowship.  Sir  William  lenner 
is  an  M.D.  Lond.,  and  not  a  blind  worshipper  01  tradi- 
tion.    On  the  present  occasion,  so  far  from  denying  what 


August  9»  1884.] 


THE   MEDICAL  RECORD. 


167 


Id  fact  could  not  be  denied,  he  got  up  and  defended  it. 

He  said  the  college  had  tried  to  get  the  general  practi- 
tioners to  join  it  and  take  the  L.R.C.P.»  which  was  in- 
stituted for  them,  and,  in  short,  why  shouldn't  general 
practitioners  be  made  Fellows?  This  was  virtually  the 
nst  of  his  argument,  but  the  Fellows  did  not  see  as  he 
saw,  and  after  a  stormy  discussion  refused  the  list  bodily. 
Hiereupon  the  Council  took  a  month  to  consider  before 
making  out  another  list,  and  have  even  taken  counseUs 
opinion.  However,  the  real  subject  of  offence  has  been 
declared  to  be  a  college  secret,  so  none  of  the  journals 
gire  any  account  of  it,  but  merely  give  a  meagre  outline 
of  what  took  place. 

Meanwhile,  those  who  have  been  offered  the  Fellow- 
ship by  the  Council  and  refused  it  by  the  Fellows  are 
in  a  nice  position.  It  is  now  customary  for  those  who 
art  proposed  by  the  Council  to  be  officially  asked 
whether  they  will  accept  the  proffered  dignity  (and  pay 
their  fifty  guineas)  before  bringing  their  names  publicly 
before  the  Fellows.  Many  years  back,  two  gentlemen 
who  had  been  duly  elected  Fellows  in  the  general  meet- 
ing of  Fellows  refused  point-blank  to  accept  the  Fellow- 
ship. To  avoid  future  indignities  of  this  kind  the  Coun- 
cil adopted  the  present  plan.     Now  where  are  they  ? 

CfSMLisifif  CkangisiHiJUSiaii^HS  OHdZhOigs  ef  OjfUtrs 
strvifig  m  th4  Meaicai  Ihdarimifii^  United  StaUs  Army, 
frm  July  27  to  August  2^884. 

Hkad,  John  F.,  Colonel  and  Surgeon.  Ordered  to 
Portsmouth,  N.  H.,  to  meet  the  Greely  party,  and  con- 
sult upon  the  proper  course  of  treatment,  with  a  view  to 
the  entire  restoration  to  health  of  Lieutenant  Greely  and 
die  men  of  his  command.  S.  O.  177,  par.  14,  A.  G.  O., 
July  30,  1884. 

Wright,  Joseph  P.,  Major  and  Surgeon.  Sick  leave 
of  absence  extended  three  months  on  surgeon's  certificate 
of  disability.  S.  O.  176,  par.  12,  A.  G.  O.,  July  29,  1884. 
Woodward,  Joseph  J.,  Major  and  Surgeon.  Sick 
leaye  of  absence  extended  six  months.  S.  O.  1 78,  par. 
9,A.G.  O.,  July  31,  1884. 

McEldsrry,  Hknry,  Captain  and  Assistant  Surgeon. 
So  much  of  S.  O.  165,  par.  12,  .A.  G.  O.,  July  16,  1884, 
as  assigned  him  to  duty  in  Department  of  the  East,  is  re- 
Toked,  and  he  is  ordered  to  report  in  person  to  the 
Snrgeon-General  of  the  Army  for  duty  in  connection 
fith  the  World's  Industrial  and  Cotton  Centennial  Ex- 
position at  New  Orleans,  La.  S.  O.  173,  par.  12,  A.  G. 
0.,  July  25,  1884- 

FiNLEY,  J.  A.,  Captain  and  Assistant  Surgeon.  Granted 
bve  of  absence  for  one  month,  with  permission  to  apply 
for  one  month  extension,  to  take  effect  about  September 
1, 1884.  S.  O.  91,  par.  2,  Headquarters  Department  of 
Texas,  July  22,  1884, 
Taylor,  A.  W.,  First  Lieutenant  and  Assistant  Sur- 
ra. Ordered  for  temporary  duty  at  Fort  Riley,  Kan. 
0- 153,  par.  I,  Headquarters  Department  of  the  Mis- 
soon,  July  29,  1884. 

Gandy,  C.  M.,  First  Lieutenant  and  Assistant  Sur- 
SeoQ.  Granted  leave  of  absence  for  one  month,  to  com- 
Bcnce  between  August  15th  and  30th,  provided  he 
fcmish  medical  attendance  at  Fort  Brady,  Mich.,  during 
las  absence.  S.  O.  144,  par.  4,  Headquarters  Depart- 
>»cntof  the  East,  July  30,  1884. 


n 


A  Man  during  a  Lifetime  of  Fifty  Years,  ac- 
wding  to  a  paper  recently  read  before  the  Academy  of 
Sciences,  Paris,  sleeps  away  an  aggregate  of  six  thousand 
^  works  away  the  same  period,  eats  away  two  thou- 
Hod  days,  walks  away  eight  hundred  days,  is  ill  during 
fcre  hundred  days, « and  amuses  himself  with  the  remain- 
b  of  his  half  century  on  earth. 


ptjedical  Stems. 


CoKTAoious  Diseases — ^Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  August  2,  1884 : 


Week  Ending 


Casts, 

July  26, 1884  . . 
August  2,  1884 

Deaths. 
July  26,  1884.  . 
August  2,  1884 


5 

J 

5 

3 


I 


150 
94 


I 


Prevention  of  Attacks  of  Cholera. — Surgeon- 
General  Cornish  says  :  "  It  is  within  the  experience  of 
all,  that  an  attack  of  cholera  in  the  individual  is  often 
aborted  by  timely  treatment.  During  an  epidemic,  what 
can  be  commoner  than  the  following  tjrpical  case  ?  A 
man  is  suddenly  seized  with  a  feeling  of  oppression  and 
sinking  about  the  epigastrium,  followed  by  two  or  three 
frequent  and  copious  watery  evacuations,  and,  if  there 
be  no  actual  sickness,  a  feeling  of  nausea  and  faintness. 
Such  attacks  often  occur  in  the  early  morning,  the  patient 
having  gone  to  bed  perfectly  well,  and  slept  soundly 
until  the  desire  to  relieve  the  bowels  was  felt.  Besides 
these  symptoms,  there  is  generally  a  clammy  skin,  a 
weak  pulse,  and  mi^ch  nervous  anxiety.  Now,  let  a  case 
of  this  nature  be  treated  instantly,  by  some  combination 
of  opium  with  a  diffusible  stimulant  (a  full  dose  of  chlo- 
rodyne  and  brandy  is  perhaps  the  best  and  simplest 
remedy  to  be  found  at  hand),  let  him  be  put  to  bed,  and 
have  warmth  applied  to  his  feet  and  epigastrium,  so  as 
to  favor  sleep.  In  nine  cases  out  of  ten,  when  the  pa- 
tient falls  asleep,  the  diarrhoea  is  checked ;  and  when  he 
awakes,  he  will  feel  quite  easy  and  comfortable.  In  the 
tenth  case,  the  remedy  may  fail  and  the  disease  progress 
until  all  the  symptoms  of  aggravated  cholera  appear  in 
their  due  order.  What  becomes  of  the  coniagium  of 
cholera,  supposing  the  disease  be  due  to  an  infective 
germ,  when  the  early  diarrhoea  is  checked?'* — Indian 
Medical  Gazette, 

The  Ethics  of  the  Skin. — Mr.  Malcolm  Morris, 
one  of  the  ablest  and  most  versatile  of  our  brilliant 
younger  school  of  dermatologists,  has,  says  the  British 
Medical  j^ournal,  made  a  decided  hit  by  his  sparkling 
and  amusing,  but  very  sensible  and  useful  lecture,  under 
this  head,  at  the  International  Health  Exhibition.  The 
lecture  was  a  pungent  criticism  of  some  of  the  morbid 
aspects  of  modem  aestheticism.  First,  it  was  shown 
physiologically  how  much  of  a  man's  individuality  lies  in 
the  skin.  Remove  an  arm  or  a  leg,  or  both  arms  and 
legs,  there  is  yet  left  an  individual  man.  But  take  away 
the  skin,  as  the  author  of  '^Sartor  Resartus"  took  away  the 
raiment,  and  individuality  is  gone.  The  color  of  the 
complexion  is  due  to  the  pigment-follicles,  the  red  color 
of  the  cheeks  to  the  terminals  of  the  biood-vesseb,  seen 
through  the  transparent  skin.  The  color  of  the  skin  is 
a  test  of  health.  But,  within  the  last  few  years,  we  have 
experienced  a  remarkable  artistic  movement.  The  ef- 
fects have  been  evident  in  the  picture-galleries,  they  have 
displayed  themselves  in  domestic  life.  Lastly,  there  has 
sprung  up  a  taste  that  can  only  be  postulated  as  a  taste 
for  disease,  decrepitude,  and  decay.  In  one  school,  we 
find  a  bevy  of  woebegone  women,  ill,  limp,  and  unwhole- 
some. The  men  are  not  more  attractive  in  a  sanitary 
sense.  They  look  like  convalescents,  ill-fed,  and  out  of 
condition.    This  school  is  not  very  wide  in  its  range,  but 


1 68 


THE  MEDICAL  RECORD. 


^ugust9, 1884 


its  influence  is  felt  beyond  the  limits  of  its  own  lines.  In 
the  paintings  of  the  older  masters  are  ruddy  Madonnas, 
clear-skinned  goddesses,  and  chubby  angels.  In  the 
more  recent  pictures,  an  etherealized  skin  is  unduly  pop- 
ular. Of  course,  this  repudiation  of  warm  tints  suited 
unhealthy  people.  Fashions  change ;  and  a  time  may 
come  when  it  will  be  fashionable  to  be  healthy,  when 
normal  hair  will  be  popular,  and  natural  skin  the  rage. 
When  this  sanitary  millennium  is  reached,  it  is  possible 
that  the  world  will  recognize  that  it  is  not  attractive  to 
daub  the  face  with  starch  and  rouge  and  bismuth,  and 
paint  after  the  manner  of  the  heathen  ;  that  the  bloom 
upon  the  peach  cannot  be  beautified  by  whitewash  ;  and 
that  no  chemical  process  can  heighten  the  tinting  of  the 
heather-bell. 

Corrosive  Sublimate  Solutions. — Sir  Joseph  Lister 
writes  to  the  British  Medical  Journal  ihzi  one  drachm  by 
weight  of  a  solution  of  one  part  of  corrosive  sublimate  in 
one  part  and  a  half  of  glycerine  contains  two-fifths  its 
weight,  or  twenty-four  grains  of  the  sublimate.  This, 
multiplied  by  1,000  (the  proportion  of  water  required), 
gives  24,000  grains,  which  is  very  nearly  three  pints. 
It  is,  however,  much  more  convenient  to  use  fluid  meas- 
ure than  weight,  and  a  fluid  drachm  to  the  glycerine  solu- 
tion referred  to  requires  four  pints  of  water  to  produce 
the  I  to  1,000  solution. 

The  Micro-organism  and  Vaccine  of  Yellow  Fe- 
ver.— Prof.  Domingo  Freire,  President  of  the  Central 
Junta  of  Public  Hygiene,  Brazil,  has  sent  to  the  Sanitary 
News  an  account  of  his  experiments  with  the  vaccine  of 
yellow  fever.  We  extract  the  following,  calling  attention 
to  the  unsatisfactory  way  in  which  he  estimates  the  pro- 
tective value  of  his  attenuated  virus :  "  The  method  of 
culture  which  I  have  followed  is  Pasteur's.  I  withdraw 
.  blood,  or  any  other  organic  liquid,  from  persons  sick  with 
yellow  fever,  or  from  the  bodies  of  the  dead,  using  the 
most  scrupulous  precautions,  and  introduce  these  liquids 
into  Pasteur's  flasks,  previously  sterilized,  and  containing 
a  solution  of  gelatine  or  beef '  bouillon. '  In  these  condi- 
tions the  microbe  develops  abundantly,  and  becomes  of  it- 
self attenuated  by  the  action  of  the  air,  which  filters  through 
the  tampion  of  amianthus  with  which  the  flask  is  corked. 
The  purity  of  these  cultures  is  demonstrated  by  microsco- 
pic examinations,  of  which  you  will  find  a  good  illustration 
in  my  memoir  '  Experimental  Studies  on  the  Contagion  of 
Yellow  Fever.*  The  microbe  appears  in  the  form  of  lit- 
tle black  points,  like  grains  of  sand  (780  diameters)  ;  in 
the  mature  form  it  presents  the  appearance  of  round 
cells  with  an  ash-gray  or  black  rim,  containing  in  their 
interior  yellow  and  black  pigment  and  some  granulations  ' 
which  will  be  the  future  spores.  These  cells  burst  at  a 
given  moment,  and  pour  out  their  contents,  1.^.,  the  spores, 
the  pigments,  and  a  nitrogenous  substance  composed  of 
ptomames,  which  I  have  isolated  not  only  from  vomited 
matter,  but  also  from  the  blood  itself^  and  from  the  urine. 
The  yellow  pigment,  being  very  soluble,  produces  the 
icteric  infiltration  of  all  the  tissues  by  a  sort  of  tinctorial 
imbibition  which  may  go  on  even  after  death  ;  the  black 
pigment,  as  well  as  the  detritus  resulting  from  the  rup- 
ture of  the  cells,  being  insoluble,  is  carried  into  the  gen- 
eral circulation  and  produces  obstructions  in  the  sanguine 
capillaries,  whence  the  apoplectic  symptoms  so  common 
in  yellow  fever,  and  in  the  urinary  tubules,  whence  the 
suppression  of  the  urine,  a  very  frequent  and  terrible 
symptom  in  this  disease.  I  have  described  this  micro- 
scopic organism  under  the  name  of  Cryptococcus  xantho- 
genicus ;  its  development  resembling  that  of  this  genus 
of  algae.  After  having  demonstrated  the  contagious  na- 
tare  of  yellow  fever  by  experiments  upon  barn-door 
fowls  (see  my  memoir),  I  made  experiments  in  preven- 
tive inoculations,  first  upon  animab  and  afterward  upon 
men.  I  did  not  fear  to  do  this,  because  a  multitude  of 
experiments  upon  animals  had  previously  convinced  me 
of  the  perfect  safety  of  inoculation  with  attenuated  cul- 
tures.    Up  to  this  date  I  have  vaccinated  four  hundred 


and  fifty  persons,  for  the  most  part  foreigners  recently  ar 
rived.  Freedom  from  yellow  fever  has  been  pronounced 
among  those  thus  vaccinated,  for  they  have  passed 
through  a  quite  severe  epidemic,  and  only  six  deaths  have 
occurred  among  the  four  hundred  and  fifty  vaccinated 
persons,  that  is  to  say,  less  than  two  in  a  hundred,  while 
more  than  a  thousand  deaths  have  occurred  among  the 
non-vacdnated  \  the  mortality  of  the  non- vaccinated  ack 
being  about  thirty  to  forty  per  hundred.  Thus,  if  we  take 
one  hundred  vaccinated  persons,  under  the  most  favor. 
able  conditions  as  regards  receptivity,  we  have  only  two 
deaths  during  the  entire  epidemic  ;  if  we  take  one  hun- 
dred non-vaccinated  sick,  we  have  thirty  lo  forty  dece- 
dents, which  gives  a  mortality  fifteen  times  greater  among 
the  non-vaccinated.  Even  if  the  mortality  were  only  ten 
times  or  five  times  less  great  among  the  vaccinated,  the 
preventive  measure  would  be  worthy  of  adoption.  The 
protective  inoculation  for  charbon  gives  an  immunity  to 
one-tenth,  and  that  of  vaccination  for  small-pox  guaran- 
tees an  immunity  to  one-fifth,  according  to  the  calcula- 
tions of  Bousquet." 

Where  Hip  Diseases  are  Treated. — Dr.  N.  M. 
Shaffer,  of  this  city,  writes :  "  Will  you  please  permit  me 
to  correct  a  misstatement  which  occurs  in  your  issue  of 
May  31st,  in  your  review  of  Dr.  Gibney's  work  on 
*Thc  Hip  and  its  Diseases?'  The  reviewer  alludes  to 
the  Hospital  for  the  Relief  of  the  Ruptured  and  Crippled, 
of  which  he  says,  *•  where  more  cases  of  hip  disease  are 
annually  treated  than  in  any  other  similar  institution  in 
the  country.'  A  few  brief  exdttcts  from  the  annual  re- 
ports of  the  Hospital  for  then<elief  of  the  Ruptured  and 
Crippled  and  those  of  the  New  York  Orthopaedic  Dis- 
pensary and  Hospital  will  prove  the  incorrectness  of 
your  reviewer's  statement.  Cases  of  hip  disease  annually 
treated  by  the  Hospital  for  the  Ruptured  and  Crippled: 
For  the  year  ending  April  30,  1879,  ^^7  5  ^^r  the  year 
ending  April  30,  1880,  160 ;  for  the  year  ending  April 
30,  1881,  170;  for  the  seventeen  months  ending  Sep- 
tember 30,  1882,  251;  for  the  year  ending  September 
30,  1883,  ^73-  Total  for  five  years  and  five  months, 
921.  Cases  of  hip  disease  annually  treated  by  the 
New  York  Orthopaedic  Dispensary  and  Hospital:  For 
the  twenty-one  months  ending  September  30,  i83o, 
401;  for  the  year  ending  September  30,  1881,  328; 
for  the  year  ending  September  30,  1882,  376;  for  the 
year  ending  September  30,  1883,  420.  Total  for  five 
years  and  nine  months,  1,525." 

Benzoin  promotes  bronchial  and  cutaneous  exhala- 
tion ;  a  large  part  of  the  acid  is  excreted  by  the  kidneys 
as  benzoic  acid,  and  a  part  is  changed  into  hippuric 
acid,  so  that  it  renders  the  urine  decidedly  add.  It  and 
the  benzoate  of  ammonia  are  very  useful  when  the  urine 
is  very  alkaline  or  ammoniacal,  and  loaded  with  phos- 
phates. It  renders  the  urine  acid,  and  arrests  ammonia- 
cal and  fermentative  changes  in  the  bladder.  Phosphatic 
calculi  are  said  to  be  dissolved  by  the  long-<:ontinued  use 
of  it.  Foul  smelling,  unhealthy,  and  sloughing  wounds, 
and  flabby  granulations  are  improved  by  the  ointment  or 
tincture.  It  destroys  fetor  and  stimulates  to  a  more 
healthy  growth.  It  has  some  antisepdc  powers,  and 
prevents  fermentation  and  putrefaction,  and  is  as  useful 
in  ulceration  of  the  bowels  as  it  is  in  open  superficial  j 
ulcers.     It  may  be  given  in  pill  form. 

Errata  in  Dr.  John  N.  Mackenzie's  Article  ojt 
CoRYZA  Vasomotoria  Periodica,  in  The  Medical 
Record  of  July  19TH. — Page  59,  first  column,-  25th  line 
from  commencement  of  article,  for  "mere "read  "more;' 
second  column,  1 8th  line  from  top  of  page,  for  "  intelligent^ 
read  "intelligible ;"  25th  line  from  top  of  page,  for  "  Dale/^ 
read  "  Daly."  Page  60,  first  column,  39th  line  from  topj 
for  "imparted"  read  "  impacted ;  "  second  column.  i5tl 
and  23d  lines  from  top,  for  "  Haek  "  read  "  Hack  ; "  44tt 
line,  for  "bulging"  read  "overlying."  Page  63,  37tl 
line  from  top,  for  "  cough  "  read  **  sneezing." 


The  Medical   Rec^^^ 

A   Weekly  Journal  of  Medicine  and  Surgery 


Vol.  26,  No.  7- 


New  York,  August  16,  1884 


Whole  No.  7x9 


©rigitml  %xXitXts. 


THE  CAUSES  OF  DISEASE, 

As  Viewed  from  the  Standpoints  of   Predisposi- 
tion, Hereditary  Influences,  Racial  Pro- 
clivities,   Epidemic  Constitution, 
and  Vital  Resistance. 

Bnng  the  Substance  of  the  Presidential  Address  delivered 
July  29,  1884,  before  the  Fifty-second  Annual  Meeting 
of  the  British  Medical  Association^  held  in  Belfast^ 
Ireland, 

By  JAMES  CUMING,  M,D.,  F.K.Q.C.P., 

inKOCrr-KLKT  op  THS  ASSOQATION,  and  PROmSOR  OF  MBDiaNB  EN  QUBBN'8 

oaaBom,  asd  physician  to  tub  royal  hospital,  bklfast,  irblano. 
i  (Special  for  Thb  Mkdical  Rboord.) 

Tax  principal  interest  in  regard  to  the  progress  of  medi- 
cal sdence  is  at  present  concentrated  on  the  study  of 
mmute  organisms  as  causes  of  disease.    The  identifica- 
doQ  of  the  special  parasites,  the  study  of  their  mode  of 
invading  the  body,  of  the  places  of  their  development,  of 
thdr  effects  in  respect  of  nutrition,  function,  and  tissue- 
change,  present  subjects  for  investigation  of  surpassing 
interest  and  engage  the  attention  of  numerous  observers. 
Evidence  is  rapidly  accumulating  which  leaves  little  room 
to  doubt  that  micro-organisms  are  the  active  agents  in 
the  production  of  epidemic  and  endemic  diseases.    A 
flood  of  light  has  been  thrown  on  some  of  the  obscurest 
points  of  pathology,  the  reproduction  and  increase  of  con- 
tagions elements,  the  immunity  acquired  by    passing 
through  a  disease  against  a  recurrence  of  the  same  mal- 
ady, and  on  the  question  of  the  incubation  and  latency 
of  contagious  diseases.     Nothing  can  be  of  greater  in- 
terest than  the  observations  on  the  attenuation  of  virus, 
opening  out  unexpected  possibilities  of  mitigating  the 
severity  of  some  of  these  scourges  of  the  human  race, 
aod  making  the  hope  of  the  ultimate  extirpation  of  several 
of  them  not  altogether  a  fantastic  one.    In  the  main  we 
have  to  look  to  foreign  observers  for  our  instruction  in 
these  subjects,  for  in  these  coimtries  the  researches  ne- 
cessary to  elucidate  such  problems  are  trammelled  by 
legislative   interference   and    markedly  discoujoiged  by 
popular  sentiment.    In  recent  years  it  had  becoipe  one 
of  the  commonplaces  of  general  addresses  on  medicine 
that  disease  was  to  be  regarded  as  simply  a  perverted  life^ 
process,  and  diat  there  was  an  essential  identity  between 
physiological  and  pathological  processes.     We  used  to 
congrattdate  ourselves  on  the  strides  we  had  made  in  ad- 
vance from  the  notions  of  the  earlier  physicians  who  re- 
prded  disease  as  an  intrusive  foreign  element  at  war 
vith  the  vital  principle.    Boerhaave  is  credited  with  being 
Ae  first  to  formulate  the  great  principle,  "  Morbus  est 
vita  praeter  naturam."    And  undoubtedly  this  conception 
fid  lead  to  clearer  notions  of  many  of  the  phenomena  of 
chronic  disease.     But  what  is  the  outcome  of  the  most 
ncent  researches  on  bacterial  action  ?    It  is,  that  when 
bacteria  enter  a  tissue  they  come  into  conflict  with  the 
proper  tissue-elements,  abstract  the  nourishment  con- 
tained in  the  juices  to  the  detriment  or  exclusion  of  the 
VHmal  cells,  and  give  rise  to  different  chemical  changes 
vlucfa  disturb   the   normal  metabolism  of  the  healthy 
parts.    After  all,  in  different  language,  the  old  idea  was 
Bot  so  very  wide  of  the  mark  as  we  supposed.    If  the 
vital  activity  of  the  parasite  gets  the  upper  hand,  the  life 


of  the  normal  cells  of  the  organism  is  enfeebled  or  de- 
stroyed, and  vice  versa.  It  is  the  old  struggle  between 
Omiuzd  and  Ahriman  within  the  sphere  of  nutritive  ac- 
tivity. Now  investigations  on  these  subjects,  can  only  be 
conducted  by  those  who  have  the  leisure  and  aptitude  for 
original  research,  and  must  accordingly  be  left  in  the 
hands  of  the  few.  But  there  is  another  vast  field  of  in- 
quiry which  is  not  beset  with  the  same  difficulties,  and 
which  forms  the  necessary  complement  of  the  study  of 
the  parasite.  We  know  that  there  must  be  a  certain  re- 
ceptivity in  the  system,  some  diminution  in  its  wonted 
powers  of  resistance,  or  some  original  proclivity— some- 
thing which  we  are  in  the  habit  of  terming  predisposition — 
which  renders  the  body  liable  to  the  attacks  of  the  para- 
site and  furnishes  an  appropriate  soil  for  its  growth.  This 
predisposition  may  be  either  a  general  one  expressed  by 
a  proclivity  in  some  countries  or  in  certain  races,  or  in 
particular  temperaments,  or  it  may  have  been  acquired 
by  the  individual  either  at  a  certain  period  of  life,  or 
under  the  influence  of  a  variety  of  causes  in  his  diet, 
occupation,  or  surroundings. 

Now  it  is  precisely  with  reference  to  these  points  that  we 
can  get  most  light— I  had  almost  said  the  only  light— from 
the  general  experience  of  the  profession.  A  great  deal 
of  medical  literature  is  founded  on  hospital  practice,  which, 
valuable  as  it  is,  wants  the  element  of  tirne.  The  float- 
ing population  of  hospitals  passes  rapidly  ifrom  under  ob- 
servation, and  it  is  only  from  the  medical  men  who  have 
known  patients  for  years,  and  often  the  stock  from  which 
they  come,  that  we  can  get  information  which  necessarily 
presupposes  continuous  observation  spread  over  long 
periods. 

It  is  in  respect  to  questions  of  this  kind,  which  are  so 
clearly  within  the  scope  of  every  practitioner  of  medicine, 
that  I  look  for  the  best  results  from  the  labors  of  the 
Collective  Invest^tion  Committee,  which  I  have  no 
doubt  will  prove  one  of  the  most  valuable  of  the  agencies 
for  good  in  this  Association  ;  and  I  am  not  without  hope 
of  a  still  larger  and  more  ambitious  effort,  which  will 
embrace  not  only  this  but  all  civilized  countries  in  its 
operation,  and  that  we  may  have  an  international  collec- 
tive investigation  of  disease.  From  such  an  organization 
we  could  obtain  an  immense  amount  of  information  on 
the  subject  of  climatic  and  telluric  influences,  and  on  the 
question  of  racial  proclivities  to  disease,  as  well  as  on 
the  important  subject  of  diathesis. 

The  subject  of  the  proclivities  of  different  races  to  dis» 
ease  is  one  of  great  interest,  and  has  been  but  little 
investigated.  The  fiacilities  which  the  vast  colonial* em- 
pire of  England  offers  for  observation  to  medical  officers 
of  the  public  services  have  enabled  them  to  see  much 
of  disease  in  different  countries  of  the  world ;  and,  no 
doubt,  there  is  a  good  deal  of  information  entombed 
in  the  army  and  navy  reports,  but  we  have  but  little 
definite  knowledge.  That  the  negro  race  enjoys  a  com- 
parative  immunity  from  yellow  fever,  and  that  even  a 
slight  admixture  of  negro  blood  brings  with  it  a  certain 
degree  of  protection  from  this  malady,  seems  well  ascer- 
tained. The  comparative  freedom  of  the  same  race  from 
stone,  and,  on  the  other  hand,  their  marked  liability  to 
elephantiasis  and  to  tetanus  are  clearly  made  out 
Again,  there  is  reason  to  believe  that  different  branches 
of  the  Aryan  or  Indo-European  family  present  some 
peculiarities  in  respect  of  liability  to  morbific  influence. 

In  France,  where,  from  the  requirements  of  military 
service,  statistics  with  respect  to  some  classes  of  affec- 


I7Q 


THE  MEDICAL  RECORD. 


[August  i6,  1884. 


tions  are  easily  accessible,  it  has  been  found  that  in  the 
provinces  where  there  is  most  Teutonic  blood  there  is  a 
notably  greater  number  of  exemptions  from  service  owing 
to  varicose  veins  and  hernia  than  those  in  which  the  in- 
habitants are  of  Celtic  origin.  On  the  other  hand,  it  is 
considered  by  some  that  the  Celtic  people  do  not  bear 
surgical  operations  so  well.  When  Velpeau  was  re- 
proached with  the  greater  mortality  after  operation  in 
Parisian,  as  compared  with  English  hospitals,  he  is  re- 
ported to  have  replied  that  the  flesh  of  a  Frenchman  was 
not  the  flesh  of  an  Englishman.  And  all  who,  in  recent 
years  have  had  the  privilege  of  visiting  the  wards  of  M. 
Charcot  in  the  Salpetridre,  have  been  able  to  notice  a 
variety  of  rare  and  complex  diseases  of  the  nervous  sys- 
tem which  are  certainly  but  rarely  to  be  met  with  in  these 
countries,  and  which  he  has  used  in  so  able  and  instruc- 
tive a  way.  Again,  it  is  probable  that  drugs  act  diflerently 
on  different  races;  the  negro,  for  example,  bearing 
mercury  better  than  the  white,  and  being  somewhat  differ- 
ently affected  by  opium.  There  are  also  the  analogous 
facts  of  the  insusceptibility  of  some  animals  to  poisons 
which  act  with  fatal  effect  on  others. 

Without  entering  on  the  subject  which  was  so  hotly 
debated  some  time  ago,  whether  a  change  of  type  in 
disease  has  taken  place,  there  can  be  no  doubt  that  a 
change  of  epidemic  constitution,  using  the  term  in  a 
wide  significance,  has  taken  place,  and  that  the  same 
diseases  do  not  prevail  with  the  same  frequency.  There 
can,  I  think,  be  no  doubt  that  typhoid  fever  is  much  more 
common  in  Ireland  than  formerly,  if  indeed  it  existed  at 
all,  and  that  typhus  is  much  less  frequent 

Now  the  important  subject  of  diathesis  is  closely  allied 
to  this  class  of  inquiry^  and  is  eminently  adapted  for 
collective  investigation.  It  is  a  condition  in  which  large 
numbers  of  individuals  are  implicated,  and  in  which  a 
large  array  of  facts  is  of  primary  importance,  and  it  is 
also  one  in  which  continuous  and  prolonged  observation 
is  eminently  and  especially  necessary. 

What  may  be  the  nature  of  the  peculiarities  of  structure 
and  of  function  which  imprint  a  particular  character  on 
the  morbid  manifestations  which  an  individual  exhibits  it 
may  not  be  possible  for  us  to  ascertain  with  certainty, 
but  there  is  no  fact  capable  of  more  overwhelming  clini- 
cal demonstration  or  which  is  of  more  cardinal  impor- 
tance in  the  management  of  disease.  It  is  a  state  in 
which,  under  the  influence  of  exciting  causes,  or  perhaps 
without  any  exciting  cause,  morbid  phenomena  are 
manifested,  diverse  in  their  seat,  their  extent,  and  their 
character,  but  united  by  a  common  pathological  bond, 
which  is  shown  in  their  mode  of  evolution  and  recession, 
and  in  a  kindred  demeanor  with  respect  to  therapeutic 
influences.  It  is  a  constitutional  state  which  exists 
before,  and  often  long  before  any  local  manifestation 
whatever,  which  is,  I  have  said,  obscure  as  regards  its 
nature,  but  distinctly  recognizable  in  its  effects,  and 
which  we  know  in  several  instances  to  arise  from  well- 
recognized  causes.  It  enrolls  the  individual  who  is 
affected  with  it  in  a  category  apart  from  those  who  are' 
not  iinder  its  influence,  and  in  this  way  approximates  to 
a  racial  peculiarity,  the  analogy  being  all  the  closer  that 
diathesis  is  in  many  instances  capable  of  transmission  to 
the  descendants  of  those  who  are  its  subjects. 

I  dwell  on  this  the  more  because  I  think  it  specially 
the  province  of  the  practical  physician,  and  because  it 
constitutes  the  most  typical  expression  of  a  class  of  facts 
which  are  forced  on  us  by  daily  experience.  We  all 
know  that  an  affection  of  the  nervous  system  or  the 
digestive  system  represents  a  different  thing,  as  regards 
the  outlook  and  the  present  danger,  in  one  family  as 
compared  to  another.  There  are  not  wanting  indica- 
tions of  a  tendency  which  takes  its  direction  from  very 
high  quarters  to  assign  an  undue  predominance  to  ana- 
tomical change  to  the  exclusion  of  constitutional  states. 
The  greatest  living  pathologist.  Professor  Virchow,  of 
Berlin,  in  his  address  at  the  International  Medical  Con- 
gress in  1 88 1  spoke  as  follows  :  ''  How  has  it  now  come 


to  pass  that  symptomatology  has  entirely  lost  the  high 
position  in  which  it  still  stood  little  less  than  a  genera- 
tion ago,  to  such  an  extent  that  in  most  universities  it  is 
no  more  taught  as  a  specialty?  Have  symptoms  no 
more  any  importance  for  the  physician  ?  Can  a  diag- 
nosis be  made  without  a  knowledge  of  symptoms  ?  Cer- 
tainly not.  But  for  the  scientific  physician  the  symptoms 
are  no  more  the  expression  of  a  hidden  power,  recognii. 
able  only  in  its  outer  workings;  he  searches  for  this 
power  itself,  and  endeavors  to  find  where  it  is  seated  in 
the  hope  of  exploring  even  the  nature  of  its  seat 
Hence  the  first  question  of  the  pathologist  and  of  the 
biologist  in  general  is,  Where  ?  That  is  the  anatomical 
question.  No  matter  whether  we  endeavor  to  ascertain 
the  place  of  the  disease  or  of  life  with  the  anatomical 
knife  or  only  with  the  eye  or  the  hand,  whether  we  dissect 
or  only  observe,  the  method  of  investigation  is  always 
anatomical." 

I  do  not  think  that  this  doctrine  will  find  acceptance 
with  practical  physicians.    We  believe  that  many  morbid 
phenomena  are  not  to  be  looked  for  as  merely  the  ex- 
pression of  local  change,  but  as  portions  of  the  effect  of 
some  specific  cause ;  that  the  disturbance  of  fimction, 
otherwise   the   symptom,  often   precedes   the   tissue  al- 
teration, and  that  we  might  be  justified  in  stating  the 
seeming  paradox,  that  the  symptom  sometimes  causes 
the  lesion  rather  than  that  the  lesion  causes  the  symp- 
tom.   Medicine  teems  with  instances  in  which  anatomical 
change  alone  would  lead  us  very  far  from  the  result  which 
clinical  observation  indisputably  establishes,  and  there 
is  no  lesson  which  experience  teaches  a  physician  more 
decisively  than  that  it  is  not  the  extent  or  degree  of 
an  inflammatory  affection  which  fiimishes  the  most  ac- 
curate measure  of  its  danger  or  the  most  reliable  indica- 
tion for  its  treatment.     Indeed,  in  dealing  with  many 
cases  of  disease  our  question  is  not.  Where  is  it  ?  but, 
What  is  it  ?   Is  it  gout  or  syphilis  or  malaria?  and  so  on; 
as  we  are  well  assured  that  if  we  have  got  the  key  to  the 
enigma  all  the  varied  anatomical  changes  will  become 
explicable,  and,  what  is  of  far  greater  moment,  will  be 
found  amenable  to  remedies.     We  have  often  occasion 
to  observe  that  anatomical  changes,  not  to  be  easily  dif- 
ferentiated, follow  from  life  processes  which  are  very  ^ 
similar.     That  symptoms  without  morbid  anatomy  are 
inadequate  and  misleading  for  the  purposes  of  the  phy- 
sician, has  been  only  too  amply  demonstrated  in  the  rec- 
ords of  medicine ;  but  it  is  no  less  certain  that  morbid 
anatomy  without  symptoms — that  is,  without  giving  a  due 
and  even  a  preponderating  weight  to  the  origin  and  prog- 
ress and  vital  character  of  the  disease — will  lead  to  error 
hardly  less  disastrous. 

It  had  been  one  of  the  characteristics  of  Irish  med- 
icine that  this  conception  of  the  essentially  vital  char-^ 
acter  of  morbid  manifestations  has  been  firmly  grasped 
and  strongly  insisted  on.  In  the  latest  work  of  Dr. 
Stokes — a  name  always  to  be  mentioned  with  honor  as 
one  who  was  an  honor  alike  to  his  profession  and  to  his 
country,  and  who  has  special  interest  for  this  Association, 
of  which  he  was  President  at  the  Dublin  meeting — ^he  says: 

*'  So  far  as  medical  experience  goes,  we  are  forced  to 
admit  that  the  foundations  for  the  healing  art  must  rest  on 
another,  if  not  a  broader  basis  than  that  of  anatomica] 
and  of  chemical  changes  in  disease.  There  are  differ* 
ences — and  for  want  of  a  better  name  we  may  call  then 
vital — which  more  intimately  relate  to  life  and  health  thai 
to  the  anatomical  or  chemical  changes  produced  by  dis 
ease ;  and  these  are  to  be  reached  by  the  study  of  the  livin| 
phenomena  of  the  body  and  of  the  influence  of  agent 
upon  them.  In  truth,  the  fruitless  attempt  to  base  med 
icine  upon  anatomical  or  even  chemical  changes  shouI< 
be  a  lesson  to  those  who  neglect  the  infinitely  varies 
mutations  of  vital  or  of  nervous  action." 

It  is  not  that  this  great  physician  did  not  recognize  L 
the  fullest  manner  the  necessity  for  the  closest  physia 
examination  during  life  and  the  most  careful  scrutiny  c 
morbid  products  :  much  of  the  labor  of  his  life,  as  is  we 


August  i6,  1884.J 


THE  MEDICAL  RECORD. 


171 


known  to  us  all,  was  devoted  to  the  elaboration  and  per- 
fection of  that  physical  diagnosis  of  which  he  was  so  con- 
smninate  a  master ;  but  that  he  refused  to  recognize  the 
i«sDlts  of  disease  as  adequate  to  the  interpretation  of 
morbid  processes. 

It  is  impossible  not  to  believe  that  if  clinical  evidence 
liad  not  been  allowed  to  be  overborne  by  pathological 
theory,  there  would  have  been  much  less  difficulty  and 
modi  less  confusion  about  the  relationship  between  pul- 
monaiy  consumption  and  struma  or  scrofula.     We  may 
sdect  this  as  an  illustration,  because  scrofula  is  an  affec- 
tion with  which  we  are  very  familiar  in  this  country,  al- 
Aoogh  probably  it  is  not  more  general  here  than  in  Eng- 
land and  Scotland.     On  broad  public  grounds  there  ^e 
few  conditions  of  greater  moment  than  scrofula  as  influ- 
encing the  well-being  and  development  of  the  youth  of 
the  community.     Defacing  the  comely  skin  and  cloud- 
ing the  clear  eye  of  childhood,  disfiguring  and  scarring 
the  neck  and  crippling  the  supple  limbs,  it  is  undoubtedly 
one  of  the  most  wide-spread  and  unsightly  forms  of  hu- 
Qian  infirmity.     Complex  in  its  causation,  and  favored 
by  all  the  concomitants  of  poverty,  insufficient  diet,  scanty 
clothing,  want  of  light  and  air  and  sunshine,  it  is  no  doubt 
in  many  instances  connected  with  the  use  of  a  dietary 
deficient  in  animal  and  vegetable  fats,  a  view  strongly 
advocated  by  the  late  Professor  Hughes  Bennett,  and 
which  has  received  the  support  of  an  authority  no  less 
eminent  than  Mr.  Jonathan  Hutchinson. 

Now  I  cannot  but  believe  that  if  the  facts  of  the  clin- 
ical history  of  scrofulous  affections  had  not  been  over- 
home  by  pathological  considerations,  there  would  be 
much  less  difficulty  in  ascertaining  the  relations  between 
scrofala  and  pulmonary  consumption.  The  reports  of  the 
Collective  Investigation  Committee  have  shown  a  pre- 
ponderating testimony  in  favor  of  the  view  toward  which 
the  current  of  medical,  as  well  as  popular,  opinion  has 
been  setting — ^tbe  communicabiiity  of  pulmonary  con- 
somption.  Now  after  a  period  during  which  consump- 
tion seemed  in  a  fair  way  of  being  considered  to  depend 
on  anything  but  tubercle,  we  have  come  to  the  convict 
tbn  that,  broadly  speaking,  tubercle  is  the  anatomical 
element  of  the  malady.  There  is  no  doubt  that  a  path* 
ological  product,  not  to  be  distinguished  from  tubercle, 
is  met  with  in  some  scrofulous  glands,  and  from  this  cir- 
comstance,  if  we  dealt  with  disease  simply  as  pathological 
anatomists,  and  not  as  physicians  and  surgeons,  we  should 
pronounce  an  opinion  very  favorable  to  the  identity  of 
the  two  affections,  and  state  that  an  individual  with  a 
scrofulous  gland  and  another  with  pulmonary  consump- 
tion were  alike  the  victims  of  tubercular  disease,  and  sil- 
though  we  would  in  doing  this  group  together  affections 
widely  different  as  regards  their  gravity  and  prognosis, 
we  would  be  acting  on  strict  pathological  lines.  But 
when  we  examine  another  numerous  class  of  strumous 
cases,  those  in  which  the  eye  and  skin  are  affected  in 
diildhood,  we  find  no  evidence  of  tubercle  whatever  i 
indeed,  in  the  progress  and  issue  of  the  affections,  decisive 
evidence  that  tubercle  is  not  present  at  all,  and  accord- 
ingly we  are  able  to  convince  ourselves,  not  only  from 
thu  circumstance,  but  firom  the  examination  of  many 
oore  advanced  forms  of  these  affections,  that  tubercle  is 
not  a  necessary  accompaniment  of  struma.  Now,  so 
smch  have  the  minds  of  pathologists  been  influenced  by 
file  occasional  presence  of  tubercle  in  struma,  that  it  has 
been  broadly  stated  that  consumption  is  a  further  stage 
ef  sarofiila  and  that  the  two  affections  are  identical,  ex- 
cept in  so  far  that  scrofula  represents  an  external  and  rudi- 
mentary form  of  the  disease  of  which  pulmonary  phthisis 
B^more  advanced  and  complete  manifestation.  At 
ftis  point  clinical  observation  has  a  right  to  enter  and 
Mver  a  formal  protest  Dealing  simply  with  the  facts 
vhich  come  under  our  notice  we  find  in  scrofula  a  con- 
dition Qx>st  common  in  the  young,  although  by  no  means 
esdnsively  confined  to  them  ;  revealing  itself  by  a  va- 
nety  of  manifestations  very  chronic  in  their  character, 
liable  to  be  set  up  by  trivial  exciting  causes,  and  remark- 


ably prone  to  affect  lymphatic  structures.  These  phe- 
nomena are  in  the  main  capable  of  easy  recognition,  and 
form  a  clinical  type  which  is  evidently  a  natural  one. 
They  are  evidences  of  a  diathesis  which  makes  those  un- 
der its  influence  a  class  different  from  others  in  the  vital 
endowments  of  their  tissue.  Of  those  who  exhibit  this 
diathesis  in  childhood,  a  considerable  proportion  grow 
up  into  fairly  healthy  men  and  women,  capable  of  per- 
forming the  duties  of  active  life,  and  giving  no  palpable 
indications  of  disease.  But  they  still  show  a  certain  vul- 
nerability of  tissue,  and  proneness  to  some  chronic  affec- 
tions of  the  same  kind,  in  fact  a  particular  "  cachet " 
which  explains  the  anomalies  in  their  vital  reaction. 
Nothing  can  be  a  more  legitimate  atld  incontrovertible  in- 
ference from  the  facts  than  that  an  individual  may  have 
been  distinctly  and  markedly  scrofulous,  and  yet  never 
exhibit  any  indications  of  consumption. 

On  the  other  hand,  of  the  consumptive  patients  who 
present  themselves  to  a  physician  for  advice  about  their 
lungs,  a  large  proportion,  estimated  at  about  eighty  or 
ninety  in  the  hundred,  have  never  had  a  history  of  scrofu- 
lous affections  in  childhood,  and  show  no  present  evi- 
dence of  the  taint.  It  is  quite  exceptional  to  And  a 
phthisical  sufferer  showing  such  indications.  Clearly,  then, 
an  individual  may  become  phthisical  without  being  scrofu- 
lous, and  considering  the  wide  diffusion  of  struma  and 
the  great  frequency  of  pulmonary  consumption  this  seems 
decisive.  In  a  recent  able  work  on  scrofiila  Mr.  Treves 
has  laid  down  the  proposition,  as  the  result  of  the  obser- 
vation of  a  great  number  of  cases,  that  there  is  a  decided 
antagonism  between  scrofulous  diseases  of  all  kinds,  and 
that  if  a  patient  has  one  severe,  or  even  well-marked 
manifestation  of  scrofula,  he  is  not  likely  to  develop 
another  strumous  disease  at  the  same  time.  Contrast 
with  this  the  well-known  law  of  Louis,  that  the  presence 
of  tubercle  in  any  organ  after  the  age  of  fifteen  involves 
as  a  necessity  its  existence  in  the  lung,  and  we  see  how 
contradictory  these  assertions  are  if  we  depend  altogether 
on  the  character  of  the  product  The  product  known  as 
tubercle  has,  after  the  age  of  fifteen,  the  property  when 
present  of  causing  the  development  of  a  similar  morbid 
product  in  the  other  parts.  Therefore,  the  tubercle 
found  in  scrofula  in  childhood  has  not  the  same  rela- 
tions to  the  system  as  the  tubercle  found  after  fifteen 
years  of  age.  It  is,  of  course,  unnecessary  to  say  that  a 
lymphatic  gland  furnishes  one  of  the  easiest  and  most  di- 
rect channels  for  the  conveyance  of  infection  into  the 
system.  Now  this  is  not  a  mere  question  of  terminology, 
for  the  attempt  to  unite  different  states  on  the  basis  of  a 
common  anatomical  character  invariably  associates  them 
in  the  mind  as  identical  in  all  essential  respects  and  is 
very  misleading. 

We  ought  to  deal  with  the  recent  observations  which 
point  to  the  bacillus  tuberculosis  in  the  same  spirit. 
When  we  are  informed  by  Koch  that  he  has  found  the 
same  parasite  in  caseous  bronchitis,  caseous  pneumonia, 
phthisical  sputa,  and  in  the  hyperplasia  of  lymphatic 
glands,  a  clinical  observer  is  justified  in  listening  to 
these  statements  with  the  greatest  interest,  but  with  con- 
siderable reserve.  He  has  a  right  to  inquire  how  is  it 
that  an  infective  granuloma  does  not  infect,  and  how  is  it 
that  an  enlarged  lymphatic  seems  to  demean  itself  in 
very  much  the  same  way,  whether  it  is  the  seat  of  a  sim- 
ple chronic  inflammatory  process  or  of  a  new  formation 
containing  an  intrusive  organism  profoundly  dangerous 
to  the  economy  and  tending  to  invade  one  part  of  the 
system  after  another. 

In  fact,  while  we  ought  to  welcome  every  new  method 
of  investigation,  while  we  ought  to  do  nothing  to  dis- 
courage the  boldest  flights  of  pathological  speculation,  to 
us  the  crucial  test  must  always  be  the  clinical  one,  the 
facts  drawn  from  the  direct  observation  of  morbid  pro- 
cesses during  life.  And  in  spite  of  any  pathological  gen- 
eralization or  anatomical  induction  we  must  hold  rigidly 
to  our  clinical  facts  and  decline  to  allow  them  to  be 
warped  or  strained  in  the  slightest  degree. 


172 


THE  MEDICAL  RECORD. 


[August  i6,  1884, 


Looking  at  the  matter  from  the  point  of  view  of  a 
practical  physician,  how  different  is  the  outlook  as  re- 
gards a  young  person  brought  to  us  with  a  strumous 
ophthalmia  and  enlarged  glands  in  the  neck  and  one  of 
the  same  age  with  a  little  dulness  and  a  few  moist  sounds 
in  the  apex  of  a  lung.  Is  this  wide  difference  in  prog- 
nosis a  question  merely  of  a  difference  in  seat  of  an  iden- 
tical pathological  product  ?  Is  there  not,  as  a  rule,  some 
antecedent  condition  which  favors,  if  it  does  not  deter- 
mine, the  appearance  of  the  morbid  state  ?  Is  it  not  a 
rare  thing  to  find  a  phthisis  beginning  without,  for  ex- 
ample, a  period  of  loss  of  appetite  or  indifferent  health 
of  some  kind  ?  Do  I  then  wish  to  say  that  there  is 
no  connection  between  scrofula  and  consumption?  I 
should  not  wish  to  be  understood  as  making  this  state- 
ment. 

There  exists  a  certain  kinship  which  makes  the  two  con- 
ditions sometimes  overlap,  and  there  is  some  evidence 
that  a  hereditary  tendency  may  sometimes  be  expressed 
in  the  one  form  and  occasionally  in  the  other. 

It  is  proposed  to  inaugurate  at  this  meeting  a  section 
devoted  to  pharmacology  and  therapeutics.  The  sub- 
jects embraced  in  this  section  have  hitherto  been  scat- 
tered through  different  departments,  but  the  increasing 
importance  of  their  study  justifies  their  being  assigned  to 
an  independent  section.  The  study  of  the  action  of 
drugs  on  the  body  both  in  health  and  in  disease,  and  the 
study  of  all  the  means  by  which  a  disease  may  be  miti- 
gated or  cured,  form  a  necessary  complement  to  the  study 
of  the  disease  itself,  and  even  throw  as  much  light  on  its 
nature. 

In  recent  years  the  efforts  in  the  direction  of  estab- 
lishing rational  therapeutics  have  been  followed  by  great 
and  encouraging  success,  while  the  search  after  spe- 
cifics has  disastrously  failed.  The  study  of  antipy- 
retics presents,  in  a  striking  light,  the  results  of  inquiry 
conducted  in  a  strictly  scientific  method  and  spirit,  and  I 
am  glad  to  find  that  one  of  the  earliest  discussions  in  the 
new  section  is  to  be  devoted  to  this  most  valuable  class 
of  agents.  New  remedies  of  unquestionable  power  are 
being  placed  in  our  hands.  It  is  impossible  to  read  the 
account  of  the  employment  of  kairin  without  being  struck 
by  its  great  efficacy  in  reducing  temperature. 

In  recent  therapeutics  we  find  also  an  illustration  of 
what  I  have  before  endeavored  to  show.  In  treating  acute 
disease,  it  is,  as  a  rule,  the  functional  trouble  that  engages 
our  attention  and  constitutes  the  aim  of  our  therapeutic 
measures.  Heat,  delirium,  circulatory  or  nutritive  dis- 
turbance, adynamic  symptoms — these  are  the  conditions 
to  which  we  direct  our  remedies.  How  comparatively 
rarely  do  we  attack  the  tissue-change  directly,  and  how 
comparatively  inoperative  are  our  therapeutic  agents  in 
this  direction.  It  is  true,  of  late  years  and  since  the  in- 
vestigations of  Pasteur,  that  wider  and  more  attractive 
possibilities  have  come  into  view,  and  the  hope  is  enter- 
tained that  agents  may  be  placed  in  our  hands  which, 
without  injuring  the  body,  may  prove  incompatible  with 
the  life  and  development  of  some,  at  least,  of  the  parasite 
organisms.  That  a  particular  salt  promotes  the  growth 
of  an  organism,  that  another  in  even  exceedingly  minute 
quantity  is  fatal  to  it,  gives  some  ground  for  the  notion 
that  it  may  be  practicable  to  destroy  some  of  these  for- 
midable enemies  even  within  the  body.  Again,  the 
methods  of  therapeutic  research  have  been  much  im- 
proved. 

The  employment  of  the  alkaloids  or  active  principles 
of  drugs  in  conducting  experiments  on  their  nature,  in- 
stead of  tinctures  and  powders  of  necessarily  uncer- 
tain strength,  has  enabled  a  degree  of  accuracy  to  be 
obtained  m  estimating  the  effects  produced  which  was 
formerly  quite  unattainable,  and  give  additional  scientific 
precision  to  the  conclusions  which  are  attained.  For  my 
own  part,  I  regard  every  advance  in  therapeutics  with 
great  interest.  The  true  dimity  as  well  as  the  chief  at- 
traction in  our  studies  lies  m  their  practical  utility.  If 
our  efforts  were  not  quickened  by  something  more  than 


love  of  knowledge  or  scientific  curiosity,  the  study  of  dis. 
ease  would  be  at  best  but  a  repulsive  one. 

''  Res  ipsa  omari  negat  contenta  doceri." 

No  doubt  there  is  an  intellectual  gratification  of  a  high 
kind  in  contemplating  a  well-ordered  field  of  knowledge 
where  the  divisions  are  clearly  mapped  out,  and  their  re> 
lations,  extent,  and  connections  can  be  accurately  under- 
stood. And  it  is  also  true  that  the  study  of  medicine 
exercises  a  powerful  and  beneficial  influence  on  the 
development  and  cultivation  of  the  intellectual  faculties. 

It  was  said  by  Dugald  Stewart  that  the  study  of  medi- 
cine had  an  important  influence  on  the  development  of 
one  of  the  keenest  intellects  of  modem  times. 

"  No  science  could  have  been  chosen  more  happily," 
he  says, ''  to  prepare  such  a  mind  as  that  of  Locke  for  the 
prosecution  of  those  speculations  which  have  immortalized 
his  name,  the  complicated  and  often  equivocal  phenoim 
ena  of  disease  requiring  in  the  observer  a  far  greater 
portion  of  discriminating  sagacity  than  those  of  physics 
properly  so  called ;  resembling  in  this  respect  much  more 
nearly  the  phenomena  about  which  metaphysics,  ethics, 
and  politics  are  concerned." 

It  is  not  possible  that  medicine  should  be  cultivated 
on  exactly  the  same  lines  as  other  sciences.  In  the  first 
place,  we  are  necessarily  precluded  from  experiment;  in  the 
next  place,  we  have  but  limited  control  over  the  subjects 
of  our  art.  It  v/as  long  ago  pointed  out  by  Bichat  that 
pathology,  the  science  of  disease,  has  no  exact  analogue 
among  the  physical  sciences.  Physiology  bears  the  same 
relation  to  living  bodies  that  medianics  and  the  like  do 
to  inert  matter.  But  there  is  no  pathology  of  the  physi- 
cal sciences.  We  cannot  suppose  gravity  to  become 
deranged  in  its  operations  or  chemical  affinity  as  subject 
to  morbid  action.  Nor  can  we  suppose  these  forces  are 
susceptible  of  remedies.  Accordingly  the  processes  of 
disease  nmst  be  made  the  subject  of  investigations  of  a 
special  character ;  to  be  conducted,  certainly,  according 
to  the  general  principles  which  govern  all  scientific  re- 
search, but  not  on  the  same  lines  or  by  the  same  method 
which  other  branches  of  inquiry  demand.  The  study  of 
life  and  its  manifestations,  of  its  beginnings  and  its  end- 
ings, conveys  the  idea  of  effort,  sometimes  baffled,  some- 
times victorious,  of  an  incessant  struggle  with  its  eviron- 
ment  compared  with  which  the  physical  forces  seem  types 
of  serenity  and  calm. 

Bacon  advised  physicians  to  raise  their  thoughts  above 
common  cases,  and  to  turn  them  to  prolonging  and  re- 
newing the  life  of  man.     But,  like  much  of  the  advice 
which  men  of  great  intellectual  attainments  have  given 
to  our  profession,  it  only  served  to  show  that  he  had 
failed  to  recognize  the  essential  conditions  of  our  art. 
It  is  given  to  philosophers  to  generalize :  to  us  the  in- 
dividual is  everything.     Aristotle  and   Seneca   advised 
that,  for  the  good  of  the  race,  delicate  children  should 
not  be  brought  up.     It  is  our  duty  to  fan   the  puniest 
flicker  of  vitality  and  to  preserve  it  from  extinction  as 
long  as  and  as  far  as  the  most  jealous  care  and  solicitude 
can  be  effectual  for  the  purpose.     What  the   sick  or 
suffering  ask  of  us  is,  to  have  their  pains  and  maladies 
mitigated  or  cured  in  the  speediest  and  most  effectual 
way.     ''Melius  anceps  remedium  quam   nullum^  is  a 
maxim  which  may  not  be  a  very  wise  one,  but  which 
certainly  would  fairly  represent  the  desire  of  the  great 
majority  of  the  human  race.     There  is  deep  truth  in  the 
saying  of  Bacon  :     "  They  be  the  least  physicians  which 
being  learned  incline  to  the  traditions  of  experience,  or 
being  empirics  incline  to  the  method  of  learning,"  for  it 
indicates  that  the  physician  should  draw  firom  all  sourcef 
of  knowledge  alike.    It  used  to  be  a  reproach  to  physi* 
cians  that  they  followed  too  implicitly  the  teaching  of 
their  masters  and  that  they  were  unduly  slow  to  accept 
new  ideas ;  at  the  present  day  we  are  no  longer  liable  to 
this  reproach.    One  is  almost  inclined  to  suggest  that 
even  an  undue  haste  is  occasionally  shown  in  adopting 
suggestions  which  rest  on  insufllcient  evidence  or  obsef« 


August  i6,  1884.] 


THE  MEDICAL  RECORD. 


173 


varioa    It  shows,  however,  a  change  in  the  habits  and 
temper  of  mind  which  is  in  close  accordance  with  the 
general  spirit  of  the  age.     It  is  well  that  novel  views 
should  meet,  as  they  are  sure  to  do  at  our  meetings,  that 
rigoroas  and  searching  criticism  which  is  the  surest  test 
of  tmth  and  which  best  proves  its  strength  and  vitality. 
It  is  one  of  the  numerous  advantages  of  a  great  assoda- 
tioD  like  this  that  different  men  may  seek  different  ser- 
vices from  its  strength  and  organization.     One  regards 
especially  its  usefulness  in  bringing  the  weight  and  in- 
fluence of  a  great  profession  to  l^ar  on  public  questions ; 
another  may  value  it  for  its  beneficial  influence  on  the 
statos  and  relations  of  the  members  of  the  profession 
themselves ;  while  others  again  attach  more  importance 
to  its  strictly  scientific  aspect,  and  desire   that  its  re- 
sources and  energy  should  be  devoted  to  the  encourage- 
ment of  research,  the  fostering  of  investigation,  and  the 
general  farthering  of  medical  science.     In  the  elasticity 
of  its  constitution,  in  the  adaptability  of  its  machinery, 
and  in  the  independence  of  its  branches,  there  is  ample 
scope  and  abundant  facility  for  the  utilization  of  the 
Taried  energies  of  its  members.     In  this  respect  it  is  no 
nnfitting  representative  and  exponent  of  the  great  pro-- 
fession  out  of  which  it  springs.     Called  as  we  are  to  deal 
irith  the  evils  and  mischances  to  which  every  form  and 
variety  of  human  activity  are  exposed,  our  points  of  con- 
tact with  the  public  are  well-nigh  innumerable. 

"Quidquid  agunt  homines,"  the  worn-out  limb,  the 
jaded  sense,  the  weary  brain  alike  come  under  our  ken. 
Eveiy  avenue  of  pleasure  may  become  the  portal  for  the 
ingress  of  pain.  And  so  our  studies  embrace  a  vast  and 
complicated  range  of  subject,  and  give  to  medical  science 
a  wide  and  far-reaching  scope  of  activity.  And  as  it  is 
DOW,  so  it  has  been  and  will  be.  When  hygiene  and 
preventive  medicine  have  done  their  utmost,  there  will 
still  be  only  too  ample  scope  for  the  physician  in  dealing 
with  the  innumerable  forms  of  human  infirmity.  The 
Ibmidations  of  our  art  have  been  laid  in  antiquity  beyond 
the  reach  of  historical  research  ;  in  this  progress  it  has 
reflected  innumerable  aspects  of  human  thought;  its 
tenns  are  the  monuments  of  forgotten  theories ;  to  its 
storehouses  of  knowledge  all  civilized  ns^tions  have 
brought  their  contributions. 

It  will  be  found  that  if  in  its  course  of  development 
medidne  has  shared  the  errors  and  shortcomings  in- 
separable from  human  progress,  its  advances  have  been 
in  the  main  fairly  abreast  of  those  made  in  other  branches 
of  knowledge. 

It  is  for  us  to  maintain  in  our  day  the  dignity  and  use- 
yoess  of  a  profession  which  has  included  in  it  so  many 
gpod  smd  fiamous  men,  and  which  has  been  for  so  many 
centuries  among  the  foremost  branches  of  intellectual 
ictirity. 


Refusing  to  be  Vaccinated. — ^There  are  persons 
here  and  there  to  be  found  who  refuse  to  be  vaccinated, 
and  some  of  them  give  the  ground  of  their  refusal  to  be 
"principle."  A  person  of  this  character  appeared  in  an 
English  court  not  long  ago  to  answer  the  charge  of  re- 
insmg  to  allow  his  three-year-old  child  to  be  vaccinated. 
The  noagistrate  fined  him,  although  his  action  was  stated 
to  be  **  on  pripciple.'*  As  the  fine  was  not  paid  and 
coold  not  be  collected,  the  offender  was  sentenced  to 
PortSDKmth  prison  for  fourteen  days,  but  without  hard 
labor.  While  in  jail  he  was  obliged  to  wear  the  criminal's 
pib,  had  to  sleep  on  a  plank  bed,  and  was  compelled  to 
pick  oakum.  He  wished  to  secure  his  own  food,  offering 
to  pajr  for  it,  but  the  authorities  declined  to  let  him  have 
loytlung  except  the  ordinary  prison  fare.  These  facts 
were  brou^t  before  the  judge  by  his  counsel,  who  con- 
tended that  he  was  not  an  ordinary  prisoner  and  should 
not  be  subjected  to  such  treatment ;  but  the  court  de- 
eded djat  the  law  had  been  broken,  and  that  the  offender 
ttnld  not  claim  any  better  treatment  than  any  o^er 
pnsoner. 


PRACTICAL  OBSERVATIONS  ON  THE  HUMAN 
EAR  AND  ITS  DISEASES,  WITH  ILLUSTRA- 
TIVE CASES. 

By  SAMUEL  SEXTON,  M.D., 

*   AUXAL  8UKGBON  TO  TMB  NEW  YOKK  BYB  AND  BAX  IKnUCAXY. 

I. — ^The  External  Ear. 

(Contmued  finom  No.  7x8,  p.  153.) 

Sometimes  it  happens  that  the  regressive  stage  runs 
on  into  a  chronic  condition,  and  the  walls  of  the  cyst 
fail  to  unite,  or  else  a  permanent  sinus  remains.  Under 
these  circumstances  it  will  be  necessary  to  destroy  the  se- 
creting surface  of  the  cyst.  This  may  be  accomplished 
either  by  the  application  of  escharotics  or  irritants  to 
the  walls  of  the  cyst,  or  by  scraping  them  with  the  cut- 
ting instrument  shown  in  Fig.  2.  In  regard  to  the  se- 
lection of  an  irritant  for  this  purpose,  I  have  found  none 
equal  to  a  strong  solution  of  iodine.  The  operation 
consists  in  making  a  tolerably  free  incision  into  the 
tumor,  or  in  enlarging  the  sinus  where  one  of  small 
size  exists,  cleansing  out  the  cavity,  and  then  freely 
painting  its  surface  with  Churchill's  solution  of  iodine. 
The  wdls  of  the  tumor  are  afterward  to  be  kept  in  con- 
tact by  pressure.  In  my  own  experience,  the  injection 
of  small  quantities  of  the  tincture  of  iodine  into  these 
tumors  has  proven  to  be  temporizing  and  unsuccessful. 
Case  II.  is  an  example  of  the  advantages  of  the  method 
recommended  above.  When  the  operation  already  de- 
scribed fails,  or  for  any  reason  seems  inadvisable,  the 
surface  of  the  walls  of  the  tumor  may  be  abraded 
throughout  with  the  fenestrated  cutting  scraper.  This 
method,  which  was  the  suggestion  of  Dr.  G.  H.  Fox,  is 
preferable  to  escharotics,  since  the  disorganization  of 
tissue  is  entirely  within  the  operator's  control.  This 
treatment  was  employed  in  Case  III.  Where  any  pro- 
jecting ed^es  or  sharp  folds  of  the  cartilage  prevent  the 
walls  commg  together,  they  may,  where  the  correcting  of 
deformity  is  desired,  be  extirpated  by  dissection.  This 
can  readily  be  done  by  making  a  sufficient  incision  down 
into  the  outer  surface  of  the  auricle,  and  with  knife  and 
scissors  removing  the  inequalities  of  the  distorted  carti- 
lage. If  thought  advisable,  the  surfaces  of  the  cavity 
may  be  afterward  treated  by  painting  with  iodine  or 
scraped.  After  the  operation  the  walls  should  be  kept 
in  contact  by  bandaging  (pressure).  In  the  writer's  ex- 
perience, otoplastic  operations  can  be  performed  with 
considerable  freedom  in  these  cases  without  fear  of  un- 
due reactive  inflammation,  the  wounds  healing  readily 
in  the  insane,  even  where  low  recuperative  action  might 
be  expected  to  exist. 

The  occurrence  of  othaematoma  in  the  mentally  sane 
is  uncommon  ;  a  glance  at  the  literature  of  the  subject 
shows  that  it  has  been  comparatively  seldom  the  subject 
of  observation  among  foreign  writers,  while  American 
authors  have  thus  far  reported  only  some  ten  cases.' 
The  writer  ventures  to  introduce  here  a  few  illustrative 
cases  occurring  in  his  own  practice,  beheving  that  an 
account  of  their  behavior  and  management  may  be  of 
interest  in  this  connection,  none  of  them  having  been 
hitherto  reported. 

Case  XI. — A  gentleman,  forty-three  years  of  age,  a 
lawyer  by  profession,  who  had  always  been  healthy,  came 
to  consult  me  on  November  22,  1876,  with  the  following 
history:  On  November  12,  1876,  he  discovered  the 
presence  of  a  small  tumor  on  the  upper  and  outer  aspect 
of  the  left  auricle.  It  gave  him  so  little  trouble  that  he 
did  not  consult  his  physician.  Dr.  W.  C.  West,  of  Mon- 
roe, Mich.,  until  a  week  afterward.  Dr.  West  then 
removed  the  small  collection  of  serum  which  the  tumor 
contained  by  aspiration.     The  effusion  now  increased 

>  Vide  C.  J.  Blake :  Statistical  Rept.  of  1,633  Cases  of  Diseases  of  the  Ear. 
treated  at  the  Mass.  Ch.  Eye  and  Ear  Inf.  during  the  year  187a  :  one  case  of 
otha:inatonia— A.  J.  Otol.,  vol.  iii.,  po.  193-196.     H.  Knapp:  Arch.  Otol.,  voL  ix.. 


pp.  i95-4oa.    Roosa:  Trans.  Am.  < 


,  voL  1.,  pp.  a3-ia7.     Kipp  :  Trans. 


X*.  OT'Soc.,  vol.  L,  p.  79.    Pomeroy:  Ibid.,  vol.  ii..  pp.  83-^6.     Buck  :  Diagnosis 
and  Treat,  of  Ear  Diseases.    Pooley  :  Msdical  Record,  vol.  xix.,  pp.  3«3-3«5- 


174 


THE   MEDICAL  RECORD. 


[August  i6,  1884. 


more  rapidly  than  before,  and  on  the  21st  of  November 
the  operation  was  repeated,  the  liquid  withdrawn  now 
being  sero-sanguinolent.  Urgent  business  at  this  time 
requiring  the  patient's  presence  in  New  York,  he  came 
to  my  office  as  stated  above.  The  tumor  was  now 
found  to  be  about  the  size  of  an  olive,  but  thinnerf  and 
to  have  a  purplish  color.  The  distention  was  causing 
some  discomfort,  and  half  a  drachm  of  bloody  serum 
was  evacuated  by  aspiration,  after  which  the  organ  did 
not  appear  much  larger  than  normal.  The  patient  re- 
mained six  days  in  New  York,  during  which  time  there 
was  but  little  change  in  his  condition  ;  the  cyst  was 
evacuated  daily,  and  twice  a  few  drops  of  tincture  of  iodine 
were  injected,  which  increased  the  irritation  somewhat 
— the  auricle  becoming  slightly  more  swollen  and  tender 
to  the  touch,  but  receding  a^ain  to  its  former  state. 
While  in  New  York  the  patient's  business  required  much 
activity  both  of  a  physical  and  mental  nature.  Before 
leaving  for  home  he  recalled  having  folded  up  the  auri- 
cle upon  itself  by  an  accidental  blow  with  his  own  hand 
while  playing  with  one  of  his  children  a  short  time  before 
he  discovered  the  cyst. 

The  patient  left  for  his  home  on  November  28th. 
He  took  a  severe  cold  during  the  journey,  and  Dr.  West 
found  him,  on  fiis  arrival  the  next  day,  suffering  very 
much  from  the  distention  of  the  cyst,  the  contents  of 
which  were  evacuated  as  before.  On  the  29th  he  was 
restless,  the  temperature  going  above  100°.  A  purga- 
tive and  aconite  were  ordered,  together  with  cooling 
lotions  and  gentle  pressure.  The  latter,  however,  could 
not  be  borne.  On  the  30th  the  patient  felt  better,  but 
the  local  trouble  was  extending,  and  now  a  colored  spot 
was  discovered  on  the  back  of  the  auricle.  Iodine  was 
injected  into  the  cyst 

From  this  time  on  the  patient  continued  to  grow 
worse ;  the  eyes  became  sensitive  to  light,  and  there 
were  darting  pains  through  the  head.  The  inflammation 
extended  itself  to  the  parts  above  the  ear ;  there  was 
now  effusion  both  in  front  of  and  back  of  the  cartilage. 
Sedative  doses  of  aconite  were  continued,  and  a  laxa- 
tive and  quinine  were  given  ;  an  incision  fully  an  inch  in 
length  was  made,  which  laid  the  anterior  aspect  of  the 
cyst  freely  open.  The  wound  was  then  packed  with  lint 
soaked  in  carbolized  oil.  "  The  operation  afforded  im- 
mediate relief,"  says  Dr.  West,  in  his  report  of  the  case 
to  me,  '^  and  in  a  few  days  there  was  an  improvement  in 
the  symptoms."  Tonics  were  then  given.  The  patient 
was  confined  to  his  bed,  however,  during  the  month  of 
December,  and  for  the  period  of  another  month  to  the 
house.  In  May,  1877,  the  auricle  was  yet  quite  tender 
to  the  touch,  and  sensitive  to  draughts  of  air,  although 
the  parts  had  been  for  some  time  entirely  healed.  When 
the  patient  came  to  see  me,  in  February,  1880,  it  was 
found  that  the  auricle  was  considerably  deformed,  the 
superior  portion  of  the  cartilage  being  much  contracted, 
the  antihelix  quite  obliterated.  In  reviewing  the  case, 
it  was  evident  that  the  long  railway  journey,  the  want 
of  proper  rest,  and,  above  all,  the  cold  contracted,  made 
a  severe  case  out  of  what  would  have  been,  perhaps,  a 
mild  one. 

Case  XII. — R.  B ,  a  packer,  forty  years  of  age, 

came  to  the  New  York  Eye  and  Ear  Infirmary,  August 
2,  1877,  with  a  small  sanguineous  tumor  on  the  outer 
aspect  of  the  left  auricle,  between  the  helix  and  anti- 
helix,  near  the  superior  border.  The  tumor  was  of  a 
deep  red  color,  and  slightly  painful  when  handled.  No 
urgent  symptoms  were  present,  and  no  subsequent  visit 
was  made. 


Case  XIII.— Ellen  M- 


a  tailoress,  aged  twenty- 


seven,  but  looks  much  older.  Came  to  the  New  York 
Eye  and  Ear  Infirmary  November  29,  1880.  She 
is  very  intemperate,  and  the  teeth  are  nearly  eroded 
away  by  caries  until  they  are  about  on  a  level  with  the 
gums.  She  states  that  one  month  ago  the  left  ear  was 
violently  jerked  by  her  husband,  and  that  the  next  morn- 
ing it  swelled  up  and  was  of  a  very  dark  purple  color. 


A  day  or  two  afterward  the  husband  opened  the  swollen 
tissues  with  a  blade  of  his  pocket-knife.  This  operation 
increased  the  swelling,  and  a  few  days  afterward  a 
"  doctor"  laid  the  outer  aspect  of  the  tumor  open  with  a 
lance.  The  cyst  now  became  intensely  swollen,  and  was 
as  large  as  the  patient's  **fist."  The  husband  then  canie 
home  again  in  a  drunken  state  and  struck  her  on  the 


Fio.  7. 

ear,  causing  a  discharge  of  its  contents  to  take  place 
from  the  superior  surface  of  the  auricle.  Flax-seed 
poultices  were  constantly  applied  to  the  ear  during  the 
attack.  The  posterior  surface  and  the  lobule  were  at 
no  time  affected.  From  the  first  the  ear  was  for  a  while 
painful.  For  the  past  two  weeks  the  swelling  has  dimin- 
ished, but  since  yesterday  it  has  again  increased  in  size, 
the  patient  says  '*  from  the  effects  of  taking  cold  in  the 
ear."  The  tumor  is  now  hard,  and  in  size  about  one 
inch  in  thickness,  and  from  above  downward  one  and 
three-fourths  of  an  inch  in  length.  It  is  oval  in  shape; 
it&  outer  surface  is  corrugated  and  somewhat  resembles 
an  almond  that  has  been  divested  of  its  outer  cortex. 
It  is  not  sensitive  to  the  touch,  and  in  color  is  dark  red, 
like  the  rest  of  the  face  and  neck.  Hearing  is  unaffected. 
The  ears  are  naturally  small.  Fig.  7  shows  the  affected 
eai's  appearance  at  the  time  of  her  first  visit.  The  local 
treatment  was  expectant ;  internally  the  tincture  of  aco- 
nite root  was  ordered  in  small  and  frequently  repeated 
doses.    Rest  and  better  personal  hygiene  recommended. 

December  6th. — She  comes  to-day  with  a  painful  al- 
veolar abscess  at  the  root  of  the  left  upper  central  in- 
cisor tooth.     Sent  to  the  dentist  to  have  tooth  removed. 

December  9th. — The  left  side  of  the  face  is  much 
swollen  from  the  presence  of  the  alveolar  abscess,  which, 
however,  is  no  longer  painful.  The  ear  is  also  without 
pain.  Were  it  not  for  the  unsightliness  of  the  abscess 
and  the  painful  mastication,  the  patient  would  not  have 
returned  to-day  for  treatment     She  was  not  again  seen. 

Case  XIV. — Mr.  S ,  a  dry  goods  merchant,  aged 

twenty-five,  came  to  consult  me  on  October  17,  1881. 
Two  months    previously  he  had  received  an  injury  to 


August  1 6,  1884.] 


THE  MEDICAL  RECORD. 


175 


the  right  ear  by  being  jammed  against  a  door  while 
in  a  state  of  intoxication.  Twelve  hours  afterward  he 
.experienced  soreness  of  the  auricle,  which  was  limited 
to  the  upper  part  of  the  helix ;  this  continued  without 
observable  swelling  for  six  weeks.  Two  weeks  ago  he 
BOticed  that  the  outer  aspect  of  the  ear  was  *' puffed 
out,"  and  two  days  later  an  incision  was  made  into  it  by 
a  physician  to  whom  he  went  at  the  time  ;  there  was  an 
csape  of  sero-sangumolent  fluid,  but  by  the  next  morn- 
ing the  incision  had  closed  and  the  cyst  had  refilled. 
Tiro  days  later  another  physician  was  seen,  who  cut  the 
parts  open  with  scissors,  and  on  the  following  day  increased 
the  size  of  the  opening  by  making  a  crucial  incision.  It 
seems  that  these  measures  were  not  sufiEicient  to  prevent 
the  filling  and  distention  of  the  sac,  and  that  five  days  be- 
fore coming  to  me  a  **  piece  was  cut  out,"  and  the  cavit>' 
then  packed  with  oakum.  Subsequently  efforts  were 
made  to  b^dage  the  ear  to  the  head.  The  oakum  was 
alloired  to  remain  for  three  days,  and  the  ear  was  then 
poulticed  When  I  first  saw  the  case  the  auricle  was 
veiy  much  enlarged,  had  an  angry  look,  and  was  of  a 
purplish  color.     (See  Fig.  8.)     It  was  not  very  tender  to 


Fig.  8. 

the  touch.  Hearing  was  unaffected.  It  was  very  evi- 
dent that  the  patient  was  in  a  state  of  chronic  alcoholism, 
and  he  was  told  that  treatment  would  be  almost  unavail- 
ing unless  he  left  off*  stimulants.  The  fluid  which  had 
again  accumulated  was  now  removed  by  aspiration,  and 
ic  was  determined  to  try  pressure  so  soon  as  the  neces- 
sary dressings  could  be  borne.  On  October  19th,  21st, 
23d,  and  30th,  improvement  was  uninterrupted ;  the  fluid 
removed  at  each  visit  was  found  to  be  more  and  more 
thin  and  pale,  and  the  quantity  less  and  less.  The  ear 
was  not  so  angry  in  appearance,  the  outlines  of  the  helix 
began  to  show  themselves,  and  the  sac  diminished  in 
size.    The  tissues  were,  however,  considerably  infiltrated.  ' 

The  patient  now  resumed  his  intemperate  habits,  with 
the  result  of  exasperating  very  much  the  condition  of  the 
ear,  the  organ  becoming  much  worse  after  each  debauch. 
Being  unable  to  improve  his  habits  in  this  regard,  the 
treatment  was  finally  suspended  before  a  cure  was  ac- 
complished. 

Remarks, — In  reviewing  the  four  cases  above,  and  the 
writer's  other  two  cases,  viz.,  Case  I.  and  Case  VIII., 
before  given,  it  will  be  convenient  to  arrange  them  in 
the  following  tabular  form  : 

The  Author's  Cases  of  Othematoma  in  the  Mentally  Sane, 


>o.  Age.    Sex. 


Occupation. 


Ear  af- 
fected. I 


Habits. 


Causes. 


^..    43      M.  Negro  minstrel     Right.     Temperate.    |  Trauma. 

^••.   35      M.  Gymnast.           Left.  |   Temperate.      Trauma. 

3-..   43      M.  Lawyer.             Left.       Temperate.    I  Trauma, 

4.  .   40      M.  Packer.             Left.       Temperate.     Trauma(?). 

5-..   27      F.  Tailoress.            Left.  1  Intemperate.    Trauma. 

*••.;  25      M.  Merchant.          Right  '  Intemperate.  ,  Trauma. 

It  will  be  seen  that  in  five  of  these  cases  the  cause 
^M  traumatic,  the  injury  in  one  of  them  being  shght.  In 


one  case  the  history  in  this  regard  is  incomplete.  Five 
were  males  and  one  was  a  female.  Hearing  was  not 
impaired  by  the  disease  in  any  of  them.  Four  of  the 
patients  were  temperate  and  two  were  intemperate. 

Of  the  ten  cases  reported  by  other  American  writers, 
the  right  ear  was  aflfected  in  four,  the  left  in  four,  both  in 
one,  and  in  one  case  the  side  affected  is  not  stated.  It 
will  thus  be  seen  that  of  the  sixteen  cases  occurring  in 
this  country,  of  which  a  full  history  is  given,  and  includ- 
ing the  writer's  six<:ases,  the  left  ear  was  most  frequently 
affected.  In  nearly  all  of  them  there  was  a  history  of 
trauma,  and  where  this  factor  was  seemingly  absent,  as 
shown  by  the  history,  it  appears  that  the  parts  about  the 
external  auditory  canal  were  the  seat  of  inflammatory 
action,  or  had  been  wounded  in  operative  procedures 
(trauma)  consisting  of  incisions  into  the  cartilage. 

One  can  well  believe  that  "  perichondritis  "  could  ex- 
tend itself  from  the  cartilage  of  the  canal  to  the  pinna  in 
such  cases.  Gruber  mentions  two  cases  where  the 
trouble  began  in  the  cartilage  of  the  canaL 

Othaematoma  in  the  insane  has  its  peculiar  interest 
also,  and  it  is  believed  that  the  following  cases  will  prove 
instructive.  They  were  placed  under  the  writer's  obser- 
vation in  the  New  York  City  Lunatic  Asylum. 

Case  XV. — Female,  aged  thirty-two  ;  under  the  care 
of  Dr.  E.  E.  Whitehome.  Has  dementia,  and  is  vio- 
lent. On  October  19,  1882,  the  left  auricle  suddenly 
became  the  seat  of  a  haematomatous  tumor  the  size  of 
a  pigeon's  tgg  ;  it  v/as  of  a  dark  purple  color,  and  was 
situated  on  &e  outer  surface.  The  swelling  impinges  on 
the  concha,  and  occludes  the  external  auditory  meatus. 
Its  progress  was  at  first  slow,  remaining  stationary  for 
six  weeks,  when  it  again  commenced  to  gradually  in- 
crease in  size  without  active  inflammatory  symptoms. 
There  was  fluctuation,  but  no  pain  ;  the  skin  was  thick- 
ened, movable,  and  very  much  less  discolored.  Outline 
of  helix  remains,  but  antihelix,  and  fossa  obliterated ; 
meatus  more  free.  The  posterior  surface  of  the  auricle 
was  unaffected.  Self-inflicted  injury,  due  to  the  long- 
continued  practice  of  violently  pressing  the  ears  with  her 
hands,  had  doubtlessly  given  rise  to  the  trouble  ;  it  was 
with  much  difficulty  that  they  were  removed  from  the 
ears  long  enough  to  permit  an  examination  of  the 
parts  being  made.  She  always  has  numerous  marks  on 
the  chest  and  elsewhere  from  self-inflicted  injuries.  The 
case  progressed  favorably  from  this  time  on,  without  any 
treatment,  spontaneous  recovery  finally  taking  place. 

Case  XVI.— Eliza  ,  aged  thirty,  admitted  Sep- 
tember 30,  1882,  with  acute  melancholia ;  under  the 
care  of  Dr.  G.  H.  Gorham  and  Dr.  H.  A.  Craig.  On 
December  23d  slight  redness  and  swelling  of  the  fossae 
of  the  left  auricle  was  observed,  the  inner  surface  of  the 
organ  being  unaffected.  On  December  24th  the  concha 
was  invaded,  occluding  the  meatus,  and  the  ear  was  poul- 
ticed. The  tumor  increased  in  size  until  the  28th,  when 
it  was  as  large  as  a  hen's  egg.  It  remained  stationary) 
the  poulticing  being  continued,  until  the  30th,  when  it 
was  laid  freely  open  by  a  horizontal  incision,  evacuating 
a  blood-clot  and  bloody  senim.  The  cavity,  which  was 
about  one  and  a  half  inch  long  by  one-half  inch  wide, 
was  syringed  out  with  carbolized  water  and  afterward 
packed  with  oakum  and  balsam  of  PenL  December 
31st  a  compress  was  applied.  The  outer  surface  of  the 
auricle  now  presented  a  smooth  convex  surface ;  the  topo- 
graphical outlines  of  the  cartilage  were  absent,  the  con- 
cha and  lobule  even  being  indistinguishable.  The  tragus 
was  unaffected,  but  was  in  contact  with  the  tumor.  The 
swollen  tissues  were  of  a  dark  purple  color.  From  the 
wound  made  by  the  incision  there  was  constant  and 
profuse  oozing  of  sero-sanguinolent  fluid,  which  trickled 
down  the  neck  of  the  patient.  The  arms  of  the  patient 
had  to  be  confined  to  prevent  further  infliction  of  self- 
injury  to  the  ear.  Subsequently  an  abscess  formed  on 
the  posterior  surface  of  the  auricle,  and  ruptured  in  that 
situation,  the  contents  discharging  fh>m  both  anterior 
and  posterior  wounds.    Gradual  healing  of  the  parts  took 


176 


THE  MEDICAL  RECORD. 


[August  16,  1884. 


place  during  January,  the  walls  of  the  cyst  uniting  and 
the  abscess  healing  by  granulation.  February  24th  ear 
completely  healed.  An  examination  in  May  showed  the 
existence  of  considerable  thickening  in  the  superior  por- 
tion of  the  auricle,  with  partial  obliteration  of  the  concha. 
The  organ  is  not  reduced  in  size  apparently,  although  it 
has  a  shrivelled  look,  the  outlines  of  the  antihelix  being 
distorted.  The  integument  was  not  markedly  adherent, 
and  its  color  normal. 

Case  XVII. — Mrs.  Barbara  K ,  aged  forty,  admit- 
ted July,  1883,  with  acute  melancholia.  Has  delusion 
that  devils  are  in  her  head,  and  hallucinations  of  hearing. 
To  prevent  devils  "crawling"  into  her  ears  and  to  ex- 
clude annoying  voices  she  tlmists  foreign  bodies,  such  as 
pebbles,  rags,  and  the  like,  into  her  ears.  On  August 
6th  the  whole  right  exterior  ear  was  observed  to  be 
intensely  hyperaemic,  but  not  thickened.  The  meatus 
externus,  however,  was  occluded  by  swelling  of  its  walls, 
and  a  little  pus  was  found  on  S3ninging  out  the  canal. 
On  the  8th  the  auricle  was  much  more  swollen,  the 
markings  becoming  indistinct.  Hot  applications  were 
made,  and  on  the  9th  pus  flowed  from  the  meatus  freely. 
On  the  13th  it  was  observed  that  considerable  purulent 
discharge  was  escaping  from  over  the  superior  margin  of 
the  concha.  Hot  fomentations  were  employed,  and  the 
rupture  healed  by  granulation  about  August  28th,  leav- 
ing the  cartilaginous  portion  of  the  external  auditory 
canal  occluded,  the  walls  being  in  contact.  The  concha 
and  fossa  of  the  helix  were  obliterated  and  the  tissues 
indurated ;  the  auricle  is  greatly  thickened  and  shrivelled. 
Hearing  is  unimpaired  on  this  (right)  side. 

On  August  nth  the  left  ear  was  found  to  be  inflamed 
also,  and  some  dirt  and  a  small  piece  of  rag  were  removed ; 
afterward  pus  escaped.  The  ear  was  then  treated  the 
same  as  the  right  had  been.  When  the  symptoms  abated 
the  auricle  remained  thickened,  and  the  canal  was  much 
reduced  in  size.  [The  clinical  history  of  this  case  was 
kindly  furnished  by  Dr.  Dent,  Assistant  Superintendent.] 

It  will  be  observed  that  in  two  of  the  above  cases 
there  were  complications  attended  with  suppuration ;  in 
one  of  them — Case  XVI. — this  was  due  probably  to  con- 
tusions of  the  parts  during  the  progress  of  the  othaema- 
toma,  and  in  the  other  case  (XVII.)  the  othaematoma 
seems  to  have  been  caused  by  trauma  and  suppurative 
inflanunation  in  the  external  auditory  canal. 

The  treatment  of  contusions  of  the  ears,  of  course,  at- 
tracted the  attention  of  ancient  physicians.  Thus  Paulus 
^3genita,  in  treating  of  these  injuries,  did  not  think  any 
treatment  required ;  since  it  was  necessary,  however,  to 
do  something,  he  recommended  that  a  local  application 
of  myrrh,  aloes,  etc.,  be  employed.  Hippocrates  found 
that  some  of  these  injuries  were  much  more  grave  in  their 
nature  than  others,  and  he  seems  not  to  have  found  their 
treatment  satisfactory.  He  shows  a  want  of  faith  in  band- 
ages or  cataplasms,  as  he  believed  that  they  favored  the 
formation  of  abscesses  and  established  suppuration  ;  the 
ear,  indeed,  seemed  to  stand  in  need  of  such  applications 
less  than  any  other  part,  and  none  were  sometimes  good 
treatment.  When  suppuration  (efiusion  ?)  threatened, 
tliere  need  be  haste  in  making  an  incision,  for  often  the 
matter  (?)  was  absorbed  again  [italics  the  writer's] .  Were 
he  forcea  to  open  it  (the  tumor  ?)  he  preferred  transfix- 
ion with  a  cautery,  since  by  means  of  this  method  the 
parts  get  well  soonest,  and  yet  it  should  be  well  under- 
stood that  deformity  will  ensue  and  the  ear  be  smaller 
than  the  other  if  thus  burnt  through.  If  an  incision 
were  decided  on  it  should  be  freely  made  on  the  upper 
(outer  ?)  side,  for,  he  says,  the  pus  (?)  is  found  to  be  sur- 
rounded with  a  thicker  covering  than  one  would  have 
supposed.  After  incisions,  which  may  not  always  be 
followed  by  evacuation  of  mucus  (serum  ?),  cataplasms 
and  pledgets  are  to  be  avoided.  The  true  nature  of  othae- 
matoma  was  unknown  in  the  time  of  Hippocrates,  and 
in  the  treatment  of  the  affection  he  was  probably  not 
aware  that  a  separation  of  the  perichondrium  from  the 
cartilage  takes  place,  and  that  the  detached  surfaces  sup- 


ply the  serum,  which  he  wrongly  believed  to  consist  of 
mucus.  The  cases  which  have  been  given,  occurring 
both  in  the  mentally  sane  and  in  the  insane,  while  show. 
ing  that  the  afiection  is  obnoxious  to  both  classes,  at  the 
same  time  teach  us  that  the  trouble  in  the  latter  is  sub- 
ject to  influences  which  usually  render  its  management 
more  difficult  than  in  the  former.  In  the  treatment  of 
othaematoma  in  the  insane  it  would  be  well  to  keep  in 
mind  that  subsequently  to  the  period  of  intensest  local 
congestion  there  is  very  often,  probably,  a  decrease  in  the 
temperature  of  the  auricle,  which  may  be  due  to  more  or 
less  complete  restoration  of  vaso-motor  dominance,  a 
condition  scarcely  distinguishable  to  the  eye  from  active 
turgescence,  although  to  the  touch  the  parts  are  cold  even« 
Opportunity  to  test  this  matter  by  thermometrical  obser- 
vations has  not  been  afforded  me,  and  I  am  therefore 
unable  to  state  the  exact  degree  of  depression  which  prob- 
ably exists.  To  pursue  this  topic  further,  however, 
would  lead  us  too  far. 

Concluding  remarks  in  regard  to  treatment. — One 
should  not  be  in  haste  to  interfere  in  these  cases ;  in 
general  it  may  be  said  that  the  dictum  of  Hippocrates^ 
namely,  that  the  employment  of  cataplasms  and  pledgets 
are  to  be  avoided,  is  as  safe  a  guide  now  as  it  was  in  his 
own  day.  But  while  excessive  poulticing  is  to  be  avoided, 
there  are  probably  some  few  cases  where  hot  fomenta- 
tions or  light  emollients  of  various  kinds  may,  when  judi- 
ciously applied,  prove  grateful  in  an  auricle  highly  in- 
flamed. As  regards  pledgets,  however,  their  employment 
is  always  liable  to  do  harm,  since  they  give  rise  to  undue 
irritation  if  employed  early,  and  the  distention  produced 
by  them  later  on,  when  thrust  into  the  cyst,  prevents  the 
walls  of  the  tumor  coming  together  and  adhering  to  each 
other.  The  employment  of  ointment  has  not,  seemingly^ 
been  a  favorite  mode  of  treatment,  but  I  have  no  doubt 
that  belladonna  ointment  would  be  beneficial  where  the 
cutaneous  circulation  is  languid.  In  tlie  regressive  stage 
I  have  found  dilute  tr.  of  arnica  of  service,  as  in  other 
contusions. 

Internally  the  fluid  extract  of  aconite  may  be  given  in 
small  and  frequently  repeated  doses ;  four  or  five  drops 
in  half  a  glassful  of  water  is  a  convenient  form  of  ear 
ploying  the  drug  ;  of  this  mixture  a  teaspi  onful  may  be 
given  every  hour  or  two,  or  oftener  if  required.  I  have 
seen  throbbing  in  the  tumor  and  local  congestion  dimin- 
ish under  this  course. 

Where  suppurative  processes  arise,  as  they  some* 
times  do,  in  the  inner  portion  of  the  auricle,  the  post- 
aural  region,  or  contiguous  to  the  cartilaginous  canal, 
the  calcium  sulphide  (Calx  Sulphurata  of  the  Pharmaco- 
poeia) is  indicated. 

That  these  patients  should  be  kept  quiet,  and  usually 
in  a  restful  attitude,  need  not  be  dwelt  on  here.  The 
self-infliction  of  further  injury,  or  its  production  by 
others,  among  insane  persons,  should  be  prevented.  At- 
tention to  general  health,  of  course,  must  not  be  over- 
looked. 

OTHEMATOMA   IN   THE   LOWER  ANIMALS. 

This  form  of  disease  is  said  to  affect  dogs,  an  ac- 
count of  its  occurrence  in  whom  has  been  given  by  Mr. 
S.  Ogier  Ward.*  Wilde  states  that  he  observed  the 
trouble  in  a  valuable  pointer.  I  have  myself  never  seen 
a  n^ell-defined  case  of  othaematoma  in  a  dog,  unless  iso- 
lated hard  lumps  in  the  pendants  portion  of  the  organ  be 
such.  It  would  seem  that  some  shrinking  of  the  auricle 
would  be  produced  by  perichondritis  rather  than  the 
**  lumps  "  alluded  to  by  writers. 

The  cat,  it  would  seem,  is  liable  to  othaematoma,  an 
example  of  which  I  was  shown  by  my  friend.  Dr.  E. 
G.  Loring,  some  months  ago.  The  animal  (a  male) 
which  was  the  subject  of  the  trouble  was  of  the  Angora 
strain,  and  was  one  year  and  a  half  old.  He  was  a  fine 
example  of  the  kind,  and,  perhaps  owing  to  high  breed- 
ing, very  excitable,  not  to  say  wild  and  uncontrollable. 

>  Loc  du 


August  1 6,  1884.] 


THE  MEDICAL  RECORD. 


177 


Over  two  weeks  before  I  saw  the  case  the  entire  in- 
ner surface  of  the  left  auricle  was  swollen  out,  the  af- 
fected organ  forming  a  long,  pointed  tumor.  The  ef- 
fusion was  gradually  reabsorbed,  and  when  the  writer 
examined  the  ear  afterward,  it  was  smaller  than  the  right 
one,  and  somewhat  thickened  and  shrivelled.  The  pres- 
ence of  some  cutaneous  trouble  in  the  post-auricular  re- 
gion and  over  the  vertex  was  noted.  The  auricle  had 
assumed  its  natural  color.  Subsequently  to  the  above. 
Dr.  Loring  informed  me,  the  right  auricle  was  affected 
in  the  same  way  the  left  had  been.  There  was  no  evi- 
dence of  the  auricle  having  been  scratched.  The  animal 
has  since  run  away. 

The  writer  has  frequently  examined  the  ears  of  pugil- 
istic cats  with  ears  deformed  by  lacerations  produced  by 
biting  and  scratching,  but  has  never  before  met  with  an 
example  where  deformity  characteristic  of  perichondritis 
existed. 

A   CASE  OF  INDIGENOUS   LEPROSY. 

By  W.  H.  GEDDINGS,  M.D., 

auchn,  s.  c. 

Miss ,  twenty  years  of  ajge,  descended  from  an  Eng- 
lish family  which  has  resided  in  South  Carolina  for  several 
generations,  was  kindly  referred  to  me  for  treatment  by 
my  friend,  Dr.  F.  L.  Parker,  of  Charieston,  S.  C.  At 
the  age  often,  while  in  the  enjoyment  of  good  health,  a 
white  spot  appeared  on  the  right  leg  immediately  below 
the  knee,  about  the  size  of  a  ten-cent  piece,  devoid  of  all 
sensation  and  not  rising  above  the  level  of  the  skin. 


Three  months  later  a  second  spot  appeared  on  the  left 
%fl)ow,  presenting  the  same  characters  as  the  first,  but 
8Dm)mitded  by  a  brownish  areola.  Similar  anaesthetic 
oacolas  continued  to  appear  during  the  first  year  of  the 
&ease  over  various  parts  of  the  trunk  and  extremities, 
poring  the  succeeding  year  the  skin  became  indurated 
a  drcumscnbed  patches  of  a  dirty  yellow  or  brownish 
color,  and  presenting  a  lardaceous  appearance.  Unlike 
tfae  maculse  these  infiltrations  were  not  anaesthetic. 
Sonihaneous  with  their  development  islets  of  yellowish 
pigment  appeared  over  various  portions  of  the  integu- 
ment, at  fii3t  about  the  size  of  a  lentil,  but  gradually 
Cila^mg  and  by  confluence  forming  extensive  patches. 
Darii^  file  succeeding  eight  years  she  remained  in  about 
be  same  condition,  but  in  February,  1882,  hemispherical 
^iberdes  about  the  size  of  a  split  pea  appeared  over  the 
^  especially  over  the  eyebrows  and  chin. 
i,Freseni  condition, —  Patient,  who  is  well  developed. 


presents  a  rather  cachectic  appearance.  The  skin,  with 
the  exception  of  a  small  area  over  the  sternum,  is  every- 
where of  a  dirty  brownish-yellow  color,  while  that  over  the 
sternum  is  abnormally  white,  presenting  the  appearance  of 
ordinary  leucopathia.  The  brownish  discoloration  is  evi- 
dently due  to  excessive  deposit  of  pigment,  which,  appear- 
ing as  small  spots,  has  gradually  spread  over  the  whole 
body.  Over  the  face  are  a  number  of  round  tubercles  of 
various  sizes,  the  more  mature  being  somewhat  larger 
than  a  fiill-grown  marrowfat  pea.  They  are  distributed 
over  the  whole  face,  but  are  much  more  numerous  on  the 
chin  than  elsewhere.  On  the  forehead,  especially  over 
and  above  the  eyebrows,  may  be  seen  the  flattened  re- 
mains of  tubercles,  which,  according  to  the  patient's 
statement,  had  disappeared  during  a  recent  attack  of 
fever.  These  latter  give  the  face-  the  peculiar  leonine 
expression  so  often  observed  in  leprosy.  The  skin  over 
the  great  toes  and  corresponding  metatarsal  bones  is 
much  swollen,  of  a  dark,  dusky  red  color,  and  is  very 
painful. 

Isolated  cases  of  leprosy  have  been  observed  in  Charles- 
ton and  its  vicinity  for  many  years,  the  present  being  the 
latest  of  a  series  of  twenty  that  have  been  brought  to  my 
notice  during  the  past  twenty-five  years.  This  comprises 
only  those  cases  that  I  have  myself  seen  or  which  have  been 
described  to  me  by  physicians  familiar  with  the  disease. 
Although  more  common  among  the  whites,  it  is  by  no 
means  confined  to  that  race,  one  of  the  patients  being  a 
full-blooded  negro  and  several  of  them  mulattoes.  Of 
the  above  cases  four  were  Jews.  In  none  of  these  cases 
was  the  disease  hereditary,  although  in  one  instance  a 
mother  and  her  daughter  were  aflected  at  the  same  time. 
In  all  these  cases  except  the  one  just  mentioned,  there 
was  not  the  slightest  evidence  of  contagion,  nor  has  it 
ever  been  deemed  necessary  to  isolate  those  affected 
with  the  disease.  When  well  enough  they  walk  about 
the  streets  of  the  city,  attracting  but  little  attention,  as 
the  people  know  from  experience  that  in  this  country 
they  run  no  risk  of  contracting  the  disease  by  coming  in 
contact  with  those  afl'et:ted  with  it.  As  isolated  cases  of 
leprosy  have  been  observed  on  the  coast  of  South  Caro- 
lina for  nearly  forty  years  without  any  apparent  increase 
in  the  number  of  cases,  it  may  safely  be  inferred  that 
there  is  but  little  danger  that  the  disease  will  ever  be- 
come endemic  in  this  section. 


FIBRO-CYST    OF    UTERUS    WEIGHING    ONE 
HUNDRED  AND  THIRTY-FIVE  POUNDS. 

By  C.  C.  STOCKARD,  M.D., 

COLUMBUS,  MIM. 

The  following  case  presents  some  points  of  interest  other 
than  the  size  of  the  tumor,  which,  so  far  as  I  can  learn,  is 
the  largest  on  record.  It  is  especially  interesting  fi-om  a 
diagnostic  point  of  view,  inasmuch  as  the  physical  char- 
acteristics of  the  fluid  contents  were  not  those  of  fibro- 
cyst,  according  to  Attlee,  but  were  those  of  ovarian-cyst, 
according  to  Drysdale,  the  post-mortem  showing  the 
tumor  to  be  the  former. 

The  patient  was  a  negro  woman,  aged  about  fifty  years, 
who  was  the  mother  of  several  children,  and  had  enjoyed 
good  health  up  to  the  time  of  the  development  of  the 
tumor. 

Some  twelve  years  ago,  according  to  her  statement, 
she  first  noticed  a  lump  in  the  right  iliac  region.  This 
continued  to  grow  larger  till  about  seven  years  ago,  when 
she  was  seen  by  two  of  our  physicians,  who  considered  it 
a  case  of  ascites  and  tapped  her,  drawing  off"  several 
gallons  of  clear  fluid.  There  was  a  reaccumulation,  and 
the  enlargement  had  reached  its  former  size  at  the  end 
of  a  year  after  the  tapping. 

A  few  years  later,  as  the  abdomen  became  greatly  dis- 
tended, there  would  occur  about  once  each  month  an 
oozing  from  the  right  side  of  the  abdomen  below  the 
navel,  which  would  continue  about  a  week,  and  during 


178 


THE  MEDICAL  RECORD. 


[August  16,  1884. 


this  time  sufficient  fluid  would  escape  to  give  her  con- 
siderable relief.  During  all  this  time  her  general  health 
continued  good,  and  she  did  the  work  about  her  house, 
cooking,  etc.  Since  February  of  this  year  there  was  no 
more  of  the  oozing,  and  she  suffered  so  from  the  disten- 
tion that  she  had  to  give  up  work  and  could  not  get 
about  without  help.  This  was  her  condition  when  I  was 
asked  to  see  her  on  May  2d.  I  found  her  truly  a  wonder- 
ful sight 


The  abdomen  measured  in  its  largest  circumference 
sixty-eight  inches,  and  from  the  ensiform  cartilage  to  the 
umbilicus,  twenty-seven  inches — the  navel  being  a  little 
below  the  knees,  as  will  be  seen  in  the  illustration.  The 
skin  in  the  neighborhood  of  the  umbilicus  was  thickened, 
and  resembled  more  the  skin  of  an  elephant  than  that  of 
a  human  being.  The  umbilicus  was  about  five  inches  in 
diameter  and  three  inches  long.  Asking  two  confreres 
to  see  the  case  with  me,  we  decided  to  tap,  to  give  re- 
lief for  a  while,  and  the  patient  was  anxious  to  be  tapped. 
Accordingly,  in  company  with  Drs.  Mayo,  Vaughan,  and 
Sykes,  I  proceeded  to  tap  her  at  2  p.m.  May  6th.  A 
few  hours  previous  to  this  the  photograph  was  taken. 

With  a  many-tailed  bandage  around  the  abdomen  in 
the  usual  way,  the  trocar  was  introduced*  about  five 
inches  above  the  umbilicus  in  the  median  line.  With- 
drawing the  trocar  from  the  canula  a  muddy  chocolate- 
colored  fluid  flowed,  a  portion  of  which  was  preserved  in 
a  clean  bottle  for  subsequent  examination.  After  several 
gallons  had  discharged  the  fluid  came  quite  slowly,  and 


another  trocar  was  introduced  four  or  five  inches  higner 
up.  From  this  puncture  came  a  clear,  slightly  amber- 
colored  fluid,  which  the  patient  said  was  like  that  drawn 
at  the  preceding  tapping.  After  running  from  this  canub 
some  little  time  it  ceased,  and  the  canula  being  partially 
withdrawn  was  pushed  into  another  cyst,  which  also  dis^ 
charged  the  clear  fluid.  After  the  flow  stopped  from 
the  &*st  canula  introduced,  it  was  withdrawn  and  inserted 
about  six  inches  above  the  second. 

The  tapping  lasted  about  two  and  one-half  hours,  and 
eight  gallons  and  seven  pints  of  fluid  was  withdrawn>-a 
considerable  amount  remaining,  which,  with  the  solid 
part  of  the  tumor,  left  the  abdomen  still  quite  large. 
Neither  of  the  two  kinds  of  fluid  coagulated  on  standing, 
even  for  several  days.  The  colored  fluid  had  a  speci&c 
gravity  of  1.02 1,  solidified  on  boiling,  and  under  the 
microscope  showed  blood-corpuscles,  granular  masses, 
an  abundance  of  beautiful  cholestcrine  crystals,  and  what 
I  considered  to  be  the  ovarian  cells  of  Drysdale.  Not 
being  an  expert  with  the  microscope,  however,  I  would 
not  insist  that  the  Drysdale  cell  was  present,  and  I  re- 
gret that  I  did  not  send  a  specimen  of  the  fluid  to  Dr. 
Drysdale  for  examination. 

The  specific  pavity  of  the  clear  fluid  was  1.015.    On 
adding  nitric  acid,  a  drop  at  a  time,  a  coagulum  the  size   , 
of  a  (£rop  would  sink  to  the  bottom  till  the  whole  solidi- 
fied.    This  fluid  contained  also  cholesterine  crystals  and 
the  cells  which  I  supposed  to  be  ovarian. 

The  patient  be^an  coughing  immediately,  but  with  this 
exception  was  quite  comfortable  for  a  few  days,  when  a 
profuse  watery  diarrhoea  set  in.  This  was  checked,  bnt 
she  continued  to  grow  weaker,  till  death  occurred  of  ex- 
haustion, on  the  sixth  day  after  being  tapped.  For  three 
days  after  the  tapping  fluid  discharged  from  the  points  oi 
puncture,  saturating  clothing  and  lidding  several  times. 

Post-mortem  examination  was  made  two  hours  after 
death  occurred,  before  there  was  rigor  mortis.  Incision 
through  the  abdominal  wall  and  peritoneum  showed  a 
network  of  veins  over  the  surface  of  the  tumor,  some  of 
them  so  large  that  we  took  them  at  first  glance  for  intes- 
tines adherent  to  the  tumor.  The  tumor  with  the  uterus 
and  ovaries  was  removed  and  the  abdominal  incision 
was  closed,  as  this  was  all  that  was  agreed  to  by  flie 
family. 

The  liver  was  seen  to  be  considerably  enlarged — ^would 
have  weighed,  I  suppose,  eight  pounds.  The  tumor  was 
attached  by  a  pedicle,  about  an  inch  in  diameter,  to  the 
posterior  portion  of  the  fundus  uteri,  and  around  the 
pedicle  the  wall  was  some  two  and  one-half  or  three 
inches  thick,  and  got  gradually  thinner. 

As  Dr.  Prudden,  the  Curator  of  the  Museum  of  the 
College  of  Physicians  and  Surgeons,  where  the  tumor 
now  IS,  has  promised  to  present  it  to  the  New  York 
Pathological  Society,  I  will  leave  a  full  description  of  it 
to  him. 

Besides  the  main  tumor  there  was  a  fibroid  in  the  uterine 
wall  about  three-fourths  of  an  inch  in  diameter,  a  small 
polypus  in  the  uterus,  and  a  cystic  tumor  of  left  ovary. 
Besides  these,  Dr.  Prudden  writes  me,  there  was  in  the 
left  Fallopian  tube  an  encapsulated  fibroma,  four  milli- 
metres in  diameter,  and  a  small  cyst  of  the  broad  ligament 
The  solid  portion  of  the  tumor  weighed  fourteen  pounds, 
and  the  fluid,  weighed  at  the  same  time,  twenty-foui 
pounds,  which,  with  the  seventy-one  pounds  drawn  at  the 
tapping,  make  one  hundred  and  eleven  pounds.  Thai 
which  escaped  after  the  tapping,  with  considerable  tha) 
was  lost  during  the  post-mortem  examination,  at  a  lov 
estimate,  was  three  gallons,  or  twenty-four  pounds ;  sc 
that  I  feel  confident  the  entire  tumor  with  its  contents 
as  it  was  before  the  tapping,  would  have  weighed  on< 
hundred  and  thirty-five  pounds  or  more. 

The  Lehigh  Valley  Medical  Associatiok  vnl 
hold  its  annual  meeting  at  Mauch  Chunk,  Pa.,  Oi 
August  19,  1884.  Dr.  Theophilus  Parvin  wUl  delive 
the  annual  address. 


August  i6,  1884.J 


THE  MEDICAL  RECORD. 


179 


gljKpin*B  at  ^OBpitaXs. 

PHILADELPHIA  HOSPITAL. 

CuNic  OF  JAMES  TYSON,  M.D. 

CHRONIC  PARENCHYMATOUS   NEPHRITIS.' 

Gkntlbmen  :  Before  giving  you  the  history  of  this  pa* 
tient,  I  desire  to  call  attention  to  some  of  the  more 
salient  points  in  his  present  condition.  In  the  first  place, 
I  ask  you  to  note  the  extraordinary  pallor  of  his  counte- 
nance and  of  his  skin  in  general.     This  was  even  more 
marked  when  he  was  first  admitted.    Another  symptom, 
which  some  of  you  may  have  noticed  already,  is  oedema. 
There  is  a  translucency  of  the  skin  which,  even  if  you 
did  not  know  that  the  limbs  were  larger  than  natural, 
would  lead  you  to  suspect  that  there  was  effusion  into 
the  subcutaneous  connective  tissue.    This  would  be  con- 
firmed by  the  effect  of  pressure,  which  produces  a  deep 
pit,  continuing  for  some  time.     This  oedema  affects  the 
feet,  legs,  and  thighs,  and  to  a  less  extent  the  hands  and 
&ce.    It  also   affects  the  abdominal  walls.     While  on 
this  point  I  shall  examine  to  see  if  there  is  any  effusion' 
into  the  peritoneal  cavity.     There  is  no  fluctuation  and 
no  dulness  on  percussion.     These  two  symptoms,  pallor 
and  oedema,  are  the  only  ones  that  are  exhibited  in  a 
saperficial  examination. 

The  histoiy  which  we  have  obtained  from  him  is  as 
follows :  He  is  forty-two  years  of  age ;  was  born  in  Ire- 
land, and  has  been  employed  around  stables  most  of  his 
life.  He  was  admitted  to  the  hospital  on  September  12, 
1883.  His  family  history  seems  to  be  good.  He  has 
heen  temperate,  and  has  no  history  of  venereal  disease, 
having  married  early.  He  has  been  suffering  from  his 
present  ailments  for  two  years.  In  the  commencement 
of  it  he  caught  a  cold,  followed  by  a  little  dry  cough, 
which  has  since  passed  away.  One  year  ago  he  noticed 
that  he  was  swelling— his  face,  and  subsequently  the  legs 
and  body.  This  is  significant,  that,  although  he  dates  his 
present  illness  two  years  back,  yet  he  did  not  notice  the 
swelling  until  one  year  ago.  Even  then,  although  he  did 
not  feel  well,  he  continued  at  his  work.  He  suffered 
also  from  nausea,  dizziness,  and  defective  vision  on  ad- 
mission, but  these  include  all  that  is  essential  in  his  con- 
dition before  admission.  One  more  fact,  however,  should 
be  stated.  He  had  diphtheria  in  the  beginning  of  his 
sickness.  This  may  be  of  some  importance  in  connec- 
tion with  the  etiology  of  his  disease. 

As  we  have  before  seen,  the  most  evident  symptoms 
are  pallor  and  swelling.  The  swelling  began  in  the  face 
and  hands,  and  this  fact  suggests  at  once  a  cause  for  it 
Given  a  case  of  general  oedema,  we  find  that  it  either 
begins  in  the  lower  extremities,  in  the  face  and  upper 
extremities,  or  it  begins  in  the  abdominal  cavity.  These 
ficts  are  cues  to  the  place  where  we  should  first  look  for 
the  disease.  It  may  be  laid  down  as  a  general  rule  that 
cedcraa,  beginning  in  the  lower  extremities,  is  due  to 
cardiac  disease ;  beginning  in  the  abdominal  sac,  to  he- 
patic disease  ;  and  beginning  in  the  face,  to  renal  disease. 
TTiis  is  not  an  inflexible  rule,  but  it  will  often  save  time 
in  the  investigation  of  a  case.  Adopting  this  rule  in  the 
present  case,  we  should  expect  to  find  the  cause  ol 
Ac  trouble  in  the  kidneys.  HeiKe  an  examination  of 
the  urine  is  suggested.  The  test  I  employ  in  your  pres- 
ence is  the  simplest,  and  under  ordinary  circumstances  is 
sofficiently  reliable ;  I  boil  the  urine  and  add  a  little  acid 
to  dissolve  any  phosphates  that  may  be  precipitated.  It 
will  be  found  that  the  albumen  will  be  precipitated  at  a 
lower  temperature  the  greater  the  amount — that  is,  if 
&ere  is  large  albuminuria  the  albumen  will  begin  to  fall 
at  a  lower  temperature  than  if  the  amount  is  small.  You 
observe  that  a  copious  precipitate  has  formed.     It  is 

^  A  cfinkad  lectore  deiivered  at  the  Philadelpliia  Hospital,  by  James  Tyson, 
zft;  '^l^  **  pby«idansto  the  hospital  and  Professor  of  Geoeral  Pathology 
•a  HortMd  Anataaay  in  the  Uaiveraity  of  Pennsylvaaia. 


scarcely  likely  that  so  large  a  deposit  could  be  due  to 
the  presence  of  phosphates,  yet  I  have  known  urine  to 
be  as  opaque  as  this  simply  from  the  deposition  of  phos- 
phates, so  that  it  is  never  safe  to  omit  the  addition  of  an 
acid.     This  precipitate  does  not  dissolve. 

This,  then,  is  a  case  of  albuminuria  as  well  as  of  drop- 
sy, and  a  case  of  large  albuminuria.  Is  this  sufficient  to 
show  that  there  is  renal  disease  ?  I  believe  that,  except 
where  there  are  evident  quantities  of  blood  or  pus  in  the 
urine,  there  is  no  one  of  the  various  causes  which  pro- 
duce albuminuria  which  will  give  such  a  large  precipitate 
of  albumen  as  we  have  here.  I  have  no  doubt,  there- 
fore, that  this  is  a  case  of  some  form  of  Brighfs  disease. 
At  the  same  time,  it  does  not  do  to  stop  here.  We  are 
not  satisfied  to-day  with  simply  learning  that  the  patient 
has  Bright's  disease,  but  we  desire  to  know  what  form  of 
the  disease  he  is  suffering.  We  have  examined  this  man's 
urine  microscopically  and  found  a  large  number  of  casts. 
These  casts  are  of  a  peculiar  kind,  and  through  their 
age  we  are  enabled  to  be  absolutely  certain  as  to  the 
diagnosis. 

As  to  casts,  let  me  briefly  call  attention  to  what  they 
are  and  how  they  are  formed.  They  are  molds  of  the 
uriniferous  tubules,  and  are  formed  of  an  albuminous 
material  which  coagulates  after  it  has  been  filtered  fi'om 
the  blood-vessels  into  the  tubules.  This  material  having 
been  poured  out,  entangles  whatever  it  may  find  in  the 
tubule.  If  the  epithelial  cells  are  loosely  attached,  these 
are  embedded  in  the  material.  After  a  time,  the  cast 
shrinks  and  becomes  smaller  than  the  tubule,  slips  out 
and  appears  in  the  urine  as  an  epithelial  cast.  If,  on  the 
other  hand,  the  uriniferous  tubule  has  its  epithelium 
closely  attached,  the  cast  slips  out,  leaving  behind  the 
epithelial  cells,  and  appears  as  a  hyaline  cast  of  small 
diameter.  This  is  the  most  favorable  form  of  casts, 
being  found  with  the  least  departure  from  health,  as 
in  congestion.  Again,  it  constantly  happens  that  the 
tubule  is  entirely  bereft  of  its  epithelium,  and  then  if  the 
albuminous  material  is  poured  out  its  diameter  is  meas- 
ured by  that  of  the  lumen  of  the  tube  plus  twice  the 
thickness  of  the  epithelium  cells.  It  slips  out  and  we 
have  a  hyaline  cast  of  large  diameter.  These  occur  in 
chronic  forms  of  Bright's  disease,  where  the  epithelium  is 
stripped  off"  and  we  have  an  empty  tube  into  which  the 
material  is  poured.  If,  instead  of  the  epithelial  cells 
being  loosely  attached  and  slightly  degenerated,  there 
happens  to  be  blood,  as  there  often  is,  in  acute  inflam- 
mation of  the  kidney,  these  corpuscles  are  imbedded  in 
the  cast,  forming  a  blood-cast.  If  the  cells  lining  the 
tubule  have  undergone  complete  fatty  degeneration  and 
have  become  filled  with  fat-drops,  or  the  degeneration 
has  even  gone  further,  so  that  the  cells  have  broken 
down  and  free  fat-drops  and  fatty  cells  become  imbedded 
in  the  cast,  it  passes  out  in  the  form  of  a/^/-  or  oil-cast. 
These  of  course  indicate  advanced  degeneration  of  the 
kidney,  or  rather  of  the  kidney- cells.  This  is  the  form 
of  casts  which  we  find  in  the  present  instance,  and  in 
addition  to  them,  fi-ee  oil-drops  and  fatty  cells ;  these 
latter  are  evidently  fi-om  the  kidney.  It  is  not  always 
easy,  and  indeed  it  requires  a  considerable  experience 
to  recognize  a  renal  cell  which  is  slightly  altered ;  but 
there  is  no  cell  from  any  other  part  of  the  genito-urinary 
tract  which  exhibits  the  characteristics  of  this  fatty  cell, 
so  that  when  fatty  cells  and  free  oil-drops  are  found  it 
may  be  concluded  that  they  come  from  the  kidneys. 

These  are  the  facts  on  which  the  diagnosis  is  based : 
the  presence  of  oedema,  which  started  m  the  face  and 
hands ;  the  existence  of  a  large  amount  of  albumen  and 
fatty  casts,  and  free  fatty  cells  and  fat-drops  on  micro- 
scopical examination. 

In  this  case  we  are  able  to  infer  with  considerable  cer- 
tainty, what  is  not  always  possible,  the  form  of  kidney 
disease  present.  This  is  a  case  of  chronic  parenchyma- 
tous nephritis.  This  means  that  the  disease  affects  the 
parenchyma  of  the  kidneys  or  the  tubules — the  essential 
secreting  substance  of  the  glands  or  the  parenchyma,  as 


i8o 


THE   MEDICAL  RECORD. 


[August  i6,  1884. 


distinguished  from  the  blood-vessels  and  intertubular 
connective  tissue.  At  the  same  time  there  is,  strictly 
speaking,  no  such  thing  as  chronic  parenchymatous  ne- 
phritis in  the  true  etymological  sense  of  the  term.  There 
is  an  acute  parenchymatous  nephritis,  because  there  is  an 
acute  inflammation  which  in  the  beginning  involves 
nothing  but  the  uriniferous  tubules.  The  acute  disease, 
however,  cannot  continue  long  before  the  interstitial  tis- 
sue becomes  involved.  This  stage,  I  believe,  has  been 
reached  in  the  patient  before  us,  and  in  every  instance 
of  chronic  parenchymatous  nephritis.  The  more  correct 
term  would  be  diffuse  nephritis,  because  we  have  in- 
volved not  only  the  parenchyma  and  the  proper  secret- 
ing substance,  but  also  the  interstitial  connective  tissue, 
probably  not  excepting  the  adventitia  of  the  blood-ves- 
sels. There  are  even  some  cases  of  acute  catarrhal 
nephritis  which  are  diffuse,  in  which  it  seems  that  simul- 
taneously both  elements  of  the  kidneys  are  involved. 
On  the  other  hand,  there  are  cases  in  which  the  intersti- 
tial connective  tissue  is  the  starting-point  of  the  disease, 
and  the  tubules  are  only  secondarily  involved.  This  is 
what  is  known  as  interstitial  nephritis. 

This,  in  a  few  words,  is  the  morbid  anatomy  of  this 
man's  kidneys :  They  are  large,  pale,  and  very  white. 
If  the  capsule  is  stripped  off,  there  will  probably  still  be 
found  white  points  scattered  over  the  surface  of  the  organ. 
It  is  the  size  and  color  of  this  kidney  that  have  given  it 
the  name  of  the  large  white  kidney.  This  white  color  is 
due  to  two  principal  causes.  In  the  first  place,  to  the 
fact  that  many  of  the  cells  have  undergone  fatty  degen- 
eration, and,  as  you  know,  fat  by  reflected  light  gives  a 
white  color.  The  little  white  spots  before  mentioned 
indicate  that  in  them  the  degeneration  is  more  advanced. 
Tissue  from  these  spots  will  show  the  uriniferous  tubules 
filled  with  oil-drops,  and  no  epithelium  cells  can  be  de- 
tected. In  the  second  place,  an  important  cause  of  the 
white  color  is  the  bloodlessness  of  the  organ.  The  fatty 
degeneration  of  the  cells  is  accompanied  by  an  increase 
of  their  number,  and  the  tubules  become  choked  with 
them ;  and  this  with  the  overgrowth  of  connective  tissue 
causes  pressure  of  the  blood-vessels,  producing  marked 
anaemia. 

A  word  in  regard  to  the  etiology  of  this  form  of  chronic 
parenchymatous  nephritis  and  diffiise  nephritis.  The  most 
frequent  causes  are  scarlet  fever  and  diphtheria,  which 
produce  the  acute  form,  which  is  very  prone  to  run  into 
the  chronic  disease.  Any  of  the  infectious  diseases  may 
produce  it.  But  it  may  also  arise  de  novo,  I  have 
called  attention  to  the  fact  that  this  man  had  diphtheria, 
but  I  stated  that  it  was  impossible  to  say  whether  or  not 
this  was  the  cause  of  the  nephritis.  We  have  no  data  to 
judge  from.  When  we  come  to  look  for  the  causes  of 
chronic  parenchymatous  nephritis  arising  de  novo^  they 
are  not  easily  found.  One  of  these  causes  is  no  doubt 
long  exposure  to  malaria ;  not  a  brief  exposure  but  the 
living  for  some  time  under  the  influence  of  a  decided 
miasmatic  influence.  Exhausting  diseases,  like  con- 
sumption, will  also  produce  this  affection.  Formerly  it 
was  thought  that  the  only  form  of  kidney  trouble  result- 
ing from  exhausting  disease  was  amyloid  degeneration, 
but  it  is  now  known  that  these  diseases  often  cause  this 
form  of  Bright*s  disease.  Another  cause  is  perhaps  long- 
continued  exposure  to  cold  and  wet,  especially  if  the 
feet  are  continuously  wet.  Acute  inflammation  of  the 
kidney  is  frequently  produced  in  this  way.  There  are, 
however,  many  cases  in  which  a  cause  cannot  be  dis- 
covered. 

Given  this  condition,  what  is  the  prospect  of  recovery 
and  what  shall  be  done  for  the  cure  of  the  disease? 
This  is  a  form  of  kidney  disease  in  which  very  much 
can  be  accomplished  by  a  judicious  treatment.  There 
is  a  most  unfortunate  popular  error  in  regard  to  the 
prognosis  of  kidney  disease.  To  most  persons  to  be 
told  that  they  have  Bright's  disease  is,  as  it  were,  a  death- 
knell  ;  but  I  would  much  rather  have  renal  disease  than 
have  consumption.  The  prospect  of  cure  is  more  reason-  | 


able,  while  the  disease  is  less  unpleasant  to  other  people. 
The  popular  notion  that  kidney  disease  is  incurable  is 
erroneous.  Some  cases  cannot  be  cured,  but  many  of 
these  could  have  been,  had  they  come  under  treatment 
earlier.  There  is  an  important  fact  in  the  pathology, 
on  which  improvement  in  this  disease  depends.  The 
large  white  kidney  sooner  or  later  undergoes  contrac- 
tion, from  the  contraction  of  the  interstitial  connective 
tissue,  and  this  is  a  favorable  change.  Of  course  this  is 
not  recovery.  It  is  really  going  on  to  a  form  of  renal 
disease  in  which  recovery  is  less  likely  to  occur,  but  it  is 
a  condition  more  compatible  with  life.  In  chronic 
parenchymatous  nephritis  the  urine  is  diminished  in 
quantity  and  of  low  specific  gravity.  When  contraction 
takes  place  the  urine  increases  in  quantity,  although  the 
specific  gravity  may  still  remain  low ;  the  amount  of 
albumen  diminishes  and  all  the  symptoms  assume  a 
more  favorable  character.  If  a  case  has  lasted  a  long 
time,  we  look  for  this  method  of  improvement  rather 
than  a  cure  by  removal  of  the  diseased  tubules  and  the 
overgrown  connective  tissue. 

What  is  the  proper  treatment  "i    There  is  one  thing 
that  must  be  done  immediately,  that  is  to  put  the  patient 
to  bed.     You  cannot  expect  any  improvement,  except 
in  rare  instances,  unless  the  patient  is  put  to  bed.    If 
this  is  done  the  patient,  often  in  the  course  of  a  few 
days,  assumes  a  better  appearance,  the  albumen  dim'm- 
ishes,  and  the  appetite  improves.     Whatever  else  is  done 
will  depend  upon  the  symptoms.     If  there  is  dropsy,  it 
should  be  removed.      A  diuretic  will   probably  be  re- 
quired.    The  best  diuretic  in  these  cases  is  digitalis.    It 
may  be  given  in  the  form  of  powder,  infusion,  or  tincture. 
The  infusion  has  the  reputation  of  being  tlie  best  form, 
and  it  is  probably  a  good  one,  but  not  better  than  the 
freshly  prepared  tincture.     The  reason  that  the  infusion 
seems  to  act  better  than  the  other  preparations,  is  prob- 
ably because  it  is  given  in  so  much  larger  doses.     It  is 
not  infrequent  to  hear  of  a  tablespoonful  of  the  infusion 
being  given,  while  only  one  grain  of  the  powder  or  ten 
drops  of  the  tincture  are  prescribed.     A  tablespoonful  of 
the    infusion  is   equivalent   to   three   and    three-fourths 
grains  of  digitalis,  while  fifteen  drops  of  the  tincture  are 
equivalent  to  one  grain  of  the  powder.     When  I  began 
to  practice  medicine,  five  drops  of  the   tincture  three 
times  a  day  was  the  universal  dose.     I  very  rarely  begin 
with  a  less  dose  than  fifteen  drops  of  the  tincture,  or  one 
grain  of  the  powder  three  or  four  times  a  day  for  an 
adult     If  I  use  a  smaller  dose  it  is  on  account  of  the 
sensitiveness  of  the  stomach.     In  determining  the  dose 
of  digitalis  and  of  other  remedies,  I  am  influenced  to  a 
certain  extent  by  the  size  of  thie  patient.     There  is  no 
doubt  that  a  man  weighing  three  hundred  pounds  re- 
quires a  larger  dose  than   one  who   weighs   only  one 
hundred  and  fifty  pounds,  for  the  same  reason  that  an 
ox  or  a  horse  requires  a  larger  dose  than  a  man. 

I  ordered  this  patient  fifteen  drops  of  the  tincture  of 
digitalis,  four  times  a  day,  but  the  improvement  was 
not  rapid.  The  nausea  was  not  increased,  but  the  dropsy 
did  not  lessen.  I  felt  that  something  more  was  neces- 
sary, I  therefore  gave  him  a  jaborandi  sweat,  which  is 
often  a  most  valuable  measure  in  this  disease.  A  favorite 
method  of  administering  jaborandi  in  this  house  is  by 
enema.  To  an  infusion  of  two  drachms  of  the  powdered 
leaves  a  pint  of  hot  water  is  added.  Of  this  one-half  is 
first  injected  into  the  bowel,  the  remainder  in  half  an 
hour,  if  sweating  does  not  occur  earlier.  The  lower 
bowel  is  very  tolerant  of  the  drug,  and  the  stomach  is 
thus  saved,  although  the  infusion  may  also  be  admin- 
istered by  the  stomach.  In  this  case  the  sweat  was 
most  successful.  Not  only  were  the  bedclothes  satu- 
rated, but  large  amounts  of  water  also  came  from  the 
mouth.  Occasionally  the  bowels  are  acted  on  and  the 
urine  increases  in  quantity.  After  this  single  sweating, 
the  dropsy  diminished  more  rapidly ;  the  urine  increased 
in  quantity.  When  first  admitted,  the  proportion  oi 
albumen  was  one-half  the  bulk  of  the  urine.      It  is  noiN 


August  i6,  1884.] 


THE  MEDICAL  RECORD. 


181 


hardly  half.     Often  the  albumen  does  not  begin  to  dis- 
appear with  the  improvement  in  the  other  symptoms. 
In  regard  to  other  means  of  giving  jarborandi,  when 
patients  are  comatose  or  in  convulsions,  it  must  either 
be  given  by  injection  into  the  bowel  or  hypodermically, 
in  the  form  of  the  active  principle,  pilocarpin.    The  latter 
is  really  the  most  elegant  method.     One-fourth  to  one- 
half  a  grain  will  usually  produce  the  desired  result.     I 
generally  give  one-fourth  of  a  grain,  and  if  the  patient 
does  not  sweat  in  fifteen  minutes  repeat  the  dose.     If 
the  symptoms  are  urgent,  I  sometimes  give  half  a  grain 
at  the  first  dose.     Another  good  remedy  is  the  fluid  ex- 
tract in  doses  of  a  teaspoonful  every  half  hour  until 
sweating  is  produced.     Sometimes  only  one  sweat  is  re- 
quired, sometimes  it  has  to  be  repeated  every  other  day 
or  once  a  week.     Jaborandi  does  have  the  effect  of  pro- 
ducing a  feeling  of  prostration.     But  I  have  never  seen 
any  harmful  results.    Some  writers  have  laid  a  great  deal 
more  stress  on  this  point  than  I  think  it  deserves.     I 
think  that  the  prostration  is  due  only  to  the  drain  from 
the  system  and  not  to  any  specific  effect.     It  is  the  pros- 
tration which  foUows  any  form  of  sweating. 

Often  the  digitalis,  which  has  previously  failed  to  act, 
will  immediately  show  its  effects  after  a  jaborandi  sweat. 
The  amount  of  serous  effusion  is  sometimes  so  great  that 
the  vessels  are  so  pressed  upon  that  they  cannot  absorb. 
The  patient  sweats,  the  pressure  is  removed  from  the 
blood-vessels,  and  the  remedy  taken  into  the  system. 
The  same  thing  follows  another  mode  of  treatment  which 
is  often  valuable — purgation.  It  is  sometimes  necessary 
to  clear  out  the  bowels  before  diuretics  will  act.  For 
this  purpose  elaterium  is  often  selected,  because  it  has 
the  property  of  producing  watery  stools.  It  may  be 
giren  in  doses  of  from  one-tenth  to  one-sixth  of  a  grain, 
filood-letting  ^u:ts  in  the  same  way.  I  recollect  a  case 
which  occurred  in  my  wards  several  years  ago.  A  patient 
had  been  receiving  large  doses  of  digitalis  which  had 
failed  to  act  For  some  reason  in  my  absence  the  resi- 
dent physician  bled  the  man.  The  digitalis  immediately 
b^;an  to  act ;  in  half  an  hour  the  pulse  was  down  to 
forty  per  minute.  It  would  seem  as  though  the  medicine 
had  lain  away  somewhere,  either  unabsorbed  or  inactive. 
WhDe  speaking  of  blood-letting,  let  me  say  that  in  the 
coma  or  convulsions  of  Bright's  disease,  blood-letting 
b  often  of  decided  benefit.  I  sometimes  employ  this 
remedy,  and  I  believe  it  would  be  well  to  employ  it  more 
frequendy. 

There  are  other  measures  to  be  employed  to  improve 
the  quality  of  the  blood  and  counteract  the  effect  of  the 
disease  on  the  system.  As  soon  as  the  stomach  .will 
admit  it  the  patient  should  receive  iron  in  full  doses. 
The  best  preparations  are  those  in  which  the  iron  is  com- 
bined with  a  vegetable  acid,  as  the  citrate,  tartrate,  and 
acetate  of  iron.  The  well  known  Basham's  mixture 
contains  the  acetate  of  iron.  The  solution  of  the 
acetate  of  iron  is  now  officinal,  but  it  may  be  prepared 
according  to  the  following  formula  : 

5.  Tinct  ferri  chloridi 3  ij. 

Ac  acet.  destillat 3  ij. 

Cura^oae f  3  j. 

Liquor  ammoniae  acetatis ad  §  vj. 

Misce. 

The  dose  of  this  is  a  tablespoonful. 

Easily  assimilable  food  should  be  given.  One  of  the 
best  forms  of  food  is  milk,  but  its  use  is  not  so  important 
in  this  disease  as  in  interstitial  nephritis.  The  milk 
should  not  be  too  rich.  A  poor  milk  or  skim  milk  is 
more  suitable ;  too  much  nitrogenous  matter  must  not 
^  given*  There  is  no  doubt  that  an  excess  of  nitro- 
genons  food  is  hurtful  in  all  forms  of  Brighf  s  disease. 
We  now  know  that  the  urea  is  derived  almost  entirely 
from  the  food  which  is  eaten.  The  old  view  was  that 
it  was  the  result  of  the  wear  and  tear  on  the  tissues. 
Bot  JQst  as  the  ashes  of  a  steam-engine  are  derived  from 
fte  fiiel  put  into  the  fire-box,  so  is  die  urea  derived  from  | 


the  food  placed  in  the  stomach.  Eggs  are  not  suitable 
food  for  cases  of  Bright's  disease,  nor  is  butcher's  meat. 
I  would  not  exclude  animal  food  altogether.  Oysters, 
fish,  white  meat,  and  game  may  be  allowed.  In  refer- 
ence to  eggs,  there  is  no  doubt  that  too  much  albumen 
in  the  blood  is  irritating  to  the  kidneys.  It  has  been 
proven  b^  experiment  that  when  large  amounts  of  albu- 
men are  mjected  into  the  blood,  the  amount  of  albumen 
excreted  exceeds  that  which  was  introduced.  This 
shows  that  something  more  must  have  been  added,  and 
this  must  have  come  from  the  blood.  Highly  albumin- 
ous food  should  therefore  not  be  given. 

An  interesting  question  is  as  to  the  cause  of  the 
anaemia.  The  common  impression  is  that  it  is  due  to 
the  drain  of  the  albumen  from  the  blood  ;  but  the  fact  is 
that  the  quantity  of  albumen  excreted,  even  in  large 
albuminuria,  is  very  small ;  and  while  it  may  contribute 
a  little  to  the  anaemia,  its  effect  must  be  very  slight. 
The  amount  of  albumen  passed  in  the  urine  throughout 
a  week  would  be  made  up  by  that  contained  in  one 
pound  of  beef.  In  fact  the  anaemia  is  partly  due  to  in- 
sufficient assimilable  food.  There  is  often  nausea  which 
prevents  the  patient  from  taking  a  sufficient  amount  of 
food.  It  must  be  admitted,  however,  that  the  loss  from 
the  blood  contributes  somewhat  to  the  effect.  Albu- 
minuric patients  should  be  clothed  in  woollen  garments, 
because  they  are  peculiarly  sensitive  to  cold. 

It  sometimes  happens  that  the  patients  get  well  up 
to  a  certain  point.  The  dropsy  passes  away  and  all  the 
symptoms  except  the  albuminuria  disappear.  The  ques- 
tion now  arises.  Is  there  anything  which  will  directly 
influence  the  quantity  of  albumen  ?  I  do  not  believe 
that  there  is  anything  that  will  do  this  except  the  gradual 
relief  of  the  circulation.  I  have  tried  astringents,  tannic 
and  gallic  acid,  and  the  astringent  salts  of  iron,  but  with- 
out benefit.  Benzoic  acid  has  been  recommended. 
Fuchsin,  one  of  the  aniline  dyes,  has  been  said  to  act  in 
this  way.  I  have  given  it  until  the  secretions  were 
stained  by  it,  but  without  any  effect  in  diminishing  albu- 
minuria. These  things  get  their  reputation  in  cases  in 
which  relief  has  followed  after  their  administration  as 
a  matter  of  coincidence  rather  than  as  a  result.  Thus 
a  pregnant  woman  has  albuminuria,  and  immediately  after 
the  burth  of  the  child  the  quantity  of  urine  increases 
and  the  albumen  diminishes.  If  benzoic  acid  or  some 
other  drug  was  being  taken  at  this  time,  a  careless  |ob- 
server  would  be  likely  to  attribute  the  improvement  to 
the  drug.  The  only  way  to  influence  these  albuminurias 
is  to  improve  the  circulation  in  the  kidneys,  and  this 
occurs  gradually  through  the  restorative  powers  of  nature, 
aided  by  such  adjuncts  as  the  physician  can  bring  to 
bear.  A  method  which  I  have  lately  used  to  a  con- 
siderable extent,  and  with  some  success,  is  the  use  of 
gentle  but  persistent  counter-irritation  over  the  region 
of  the  kidney,  drawing  the  blood  to  the  surface  into  the 
branches  of  the  lumbar  arteries  which  connect  with  the 
renal  arteries.  It  is  not  easy  to  produce  gentle  and 
persistent  counter-irritation.  The  only  way  in  which  I 
have  been  able  to  do  this  has  been  by  means  of  weak 
mustard  plasters,  prepared  with  molasses  or  white  of 
egg.  Msule  in  this  way  the  plaster  does  not  burn  so 
much  ahd  may  be  worn  constantly,  or  nearly  so;  for 
this  is  necessary,  that  the  irritation  should  be  persistent. 
Under  this  treatment  the  albumen  gradually  diminishes 
and  sometimes  disappears  altogether,  when  all  other 
measures  fail  to  influence  it. 


Unusual  Susceptibility  to  Small-pox  and  Vac- 
cine.—Dr.  W.  Thornton  Parker,  of  Fort  Union,  N.  M., 
writes  :  **  Among  the  recruits  lately  arrived  at  this  post 
is  a  man  who  was  vaccinated  successfully  when  two 
years  of  ag6.  Soon  afterward  he  contracted  small-pox, 
and  in  May  of  this  year  was  again  successfully  vac- 
cinated." 


l82 


THE  MEDICAL  RECORD. 


[August  i6,  1884. 


The  Medical  Record 


A  Weekly  journal  0/ Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


PUBUSHED  BY 

WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 
New  York,  August  16,  1884. 

THE  INTERNATIONAL  MEDICAL  CONGRESS. 

Cable  despatches  up  to  the  hour  of  our  going  to  press 
state  that  the  eighth  session  of  the  International  Medical 
Congress  was  formally  opened  on  Sunday,  August  loth,  at 
Copenhagen,  Denmark,  by  the  President,  Professor  Pa- 
num,  of  Copenhagen,  who  delivered  an  address  of  wel- 
come to  the  members,  the  King  and  Queen  of  Denmark, 
the  Council  of  State,  and  the  King  and  Queen  of  Greece 
being  present.  The  attendance  was  large,  comprising 
over  three  hundred  Danes,  one  hundred  Swedes,  about 
one  hundred  Norwegians,  and  nearly  eleven  hundred  med- 
ical men  of  other  nationalities.  America  was  fairly  rep- 
resented, as  was  also  Great  Britain,  France  giving  the 
larger  proportion  of  the  latter  number. 

The  scientific  work  of  the  association  was  duly  inau- 
giu-ated  on  Monday  and  was  divided  into  that  of  general 
sessions  and  meetings  of  sections.  Considering  the 
amount  of  material  announced  and  the  lack  of  an  under- 
standing as  to  a  definite  programme  of  proceedings,  there 
was  at  first  considerable  difficulty  in  settling  upon  a  sys- 
tematic arrangement  and  order  of  subjects ;  but  the  ses- 
sions, general  and  special,  as  will  be  seen,  were  kept  well 
employed  and  were  well  attended. 

It  is  impracticable  at  this  stage  of  the  proceedings  to 
give  a  full  account  of  the  doings  of  the  Congress,  it  being 
still  in  session  as  we  write,  but  the  accounts  received 
thus  far  show  how  much  of  strictly  scientific  work  was 
done.  In  our  next  issue  we  hope  to  publish  still  fuller 
cable  despatches,  with  such  addresses  received  as  shall 
be  deemed  interesting  to  out  readers.  Our  arrangements 
with  our  correspondent  at  Copenhagen  are  as  perfect  to 
this  end  as  has  been  possible  to  make  them,  and  we 
trust  to  our  ability  in  giving  the  earliest  authentic  ac- 
counts of  the  work  of  the  Congress  obtainable  on  this 
side  of  the  Atlantic. 

It  has  been  announced  that  the  session  will  close  on 
Saturday,  after  a  full  week  of  work,  and  we  have  reason 
to  expect  that  the  summarized  results  will  be  of  sufficient 
interest  to  our  readers  to  warrant  the  necessary  pecuniary 
outlay  for  cable  despatches  necessary  to  the  fulfilment  of 
our  promise. 

It  is  quite  probable  that  the  next  congress  will  be 
held  in  America,  as  the  invitation  on  behalf  of  the 
medical  profession  here  through  the  American  Medical 
Association  has  been  favorably  received,  and  will  doubt- 
less be  acted  upon  accordingly.  No'  definite  action  has 
yet  been  decided  upon  up  to  our  present  advices. 


THE  DOCTOR  IN  FICTION. 
It  is  to  be  presumed  that  doctors  are  gratified  to  find 
that  novel-writers  have  of  late  taken  them  up  so  largely. 
Few  of  the  more  prominent  novelists  have  now  left  us 
untouched.     The  late  Mr.  Charles  Reade  has  recorded 
the  wonderful  deeds  of  a  medical  woman,  in  order  to 
prove  to  the  dull-eyed  public  that  medicine  was  an  art  in 
which  the  gentler  sex  could  shine.     Mr.  Howells  has  in. 
troduced  his  *'  Dr.  Breen,"  and  has  therein  shown  that  the 
general  tendency  of  women,  however  medically  inclined, 
is  to  collapse  on  the  matrimonial  rock.     Miss  Phelps 
some  time  ago  tried  to  portray  an  impossible  creature 
who  was  called  "  Dr.  Zay."     She  was  described  as  being 
lovely,  scientific,  and  homoeopathic     By  virtue  of  the 
first  two  qualities  she  cured  a  patient,  and  subsequently 
became  his  wife.     We  do  not  know  what  lesson  Miss 
Phelps  sought  to  inculcate — if  any ;  but  it  strikes  us  that 
to  try  and  make  something  heroic  out  of  that  last  out- 
rage upon  common-sense — a  homoeopathic  woman— is  a 
great  waste  of  talent. 

Mr.  Henry  James  has  given  an  excellent  portrait  of  a 
New  York  fashionable  physician,  in  his  ^'Washington 
Square."  More  recently  he  has  been  marrying  a  young 
American  doctor  to  ^'  Lady  Barbarina,"  the  daughter  of 
an  English  peer,  and  showing  the  effects  of  the  union  of 
American  medicine  with  English  aristocracy.  The  re- 
sult is  not  a  happy  one  to  the  contracting  parties,  and 
the  young  doctor  is  obliged  to  take  down  his  sign,  give 
up  his  researches  into  cerebro -spinal  meniagitis,  and  live 
in  London  with  his  mother-in-law.  We  are  informed 
incidentally  of  the  peculiar  absence  of  social  position 
which  the  average  English  doctor  is  accorded  by  his 
hereditary  legislators. 

We  cannot  say  whether  Mr.  Cable,  in  his  **Dr. 
Sevier,"  is  writing  a  novel  which  is  to  solve  some  social 
problem  or  simply  to  portray  a  unique  character. 
Doubtless  our  Louisiana  colleagues  can  better  appreciate 
his  work. 

In  a  recently  published  novel,  entitled  "  A  Country 
Doctor,"  Miss  Jewett  brings  up  again  the  question  of 
wonjen  and  the  study  of  medicine.  It  must  be  confessed 
that  her  novel,  though  somewhat  prolix,  deals  with  the 
subject  at  issue  in  a  way  that  commands  respect  Her 
heroine  is  a  young  woman  who  is  brought  up  under  the 
tutelage  of  a  '*  country  doctor,"  himself  a  charmingly 
and  truthfully  drawn  character.  She  feels  as  she  grows 
up  that  she  possesses  an  especial  fitness  for  practising 
medicine,  and  an  overwhelming  certainty  that  she  is  not 
like  other  women.  She  wants  to  practise  medicine,  not 
to  be  a  wife  and  mother.  Her  trial  comes  when  she  falls 
in  love  with  a  not  over-brilliant  young  man.  After  a 
hard  struggle  she  gives  him  up,  and  makes  the  Hippocra- 
tic  oath  have  something  of  the  significance  of  a  conven- 
tual vow. 

It  is  not  improbable  that  there  are  some  such  women  | 
as  Miss  Jewett  portrays,  women  who  have  a  certain 
instinctive  aptitude  for  making  sick  people  feel  better,  I 
and  who  can  follow  out  this  aptitude  better  as  doctors 
than  as  nurses.  Their  number  is  naturally  very  small. 
In  "  A  Country  Doctor  *'  their  feelings  and  ambitions 
are  well  shown.  Here  is  none  of  the  namby-pamby 
transcendentalism,  the  globules  and  matrimony  of  ''  Dr. 
Zay." 


August  16,  1884.] 


THE  MEDICAL  RECORD. 


183 


THE  PATHOLOGY  OF  OBESITY. 
PltoFESSOK  Ebstein's  monograph  upon  the  treatment  of 
corpulence  has  excited  a  large  amount  of  attention  from 
the  medical  profession,  and  has  called  forth  a  consider- 
able number  of  articles  upon  the  same  subject.    Ameri- 
can physicians  do  not  meet  so  many  cases  of  obesity  as 
do  their  European  canfrtres.     Nevertheless,  the  disease 
exists  here,  and  it  will  be  worth  while  for  our  readers  to 
keq>  themselves  acquainted  with  the  progress  made  in 
oar  knowledge  regarding  it    Probably  most  physicians 
who  have  tried   to  reduce    obesity  by  prescribing  the 
regulation  anti-fat  diet  have  been  disappointed.     Doubt- 
less this  is  often  the  fault  of  the  patient  or  the  environ- 
ment; but  one  cannot  resist  the  conclusion  that,  aside 
from  all  extraneous  considerations,  anti-fat  diets  and  Ban- 
tittgism  generally  are  often  inherently  befficient     The 
very  fact  that  £bstein's  work  has  been  so  eagerly  read 
points  to  this  same  conclusion.     Ebstein  has  certainly 
famished  the  profession  with  some  valuable  and  practical 
hints  in  this  direction.     But  it  is  yet  too  soon  to  say  that 
his  new  diet  of  fat  and  nitrogenous  food  is  to  be  any 
more  successful  than  earlier  ones.     We  have  already  ex- 
pressed the  opinion  that  theoretically  it  has  but  feeble 
support,  while,  practically,  it  is  known  that  Voit   has 
actually  fattened  animals  with  fatty  and  nitrogenous  food. 
Leaving  this  question  for  the  future  to  decide,  therefore, 
we  would  now  call  attention  to  an  interesting  review  of 
the  subject    of  obesity,  or  morbidly  great    corpulence, 
which  Professor  Kisch,  of  Prague,  has  recently  con- 
tributed to  the  Deutsche  Medizinal  Zeitung. 

In  normal  conditions  there  is  a  tendency  for  the  de- 
posit of  fat  in  the  cormective  tissue  of  certain  regions, 
such  as  the  subcutaneous  tissue — especially  of  the  abdo- 
men and  buttocks — also  in  the  mesentery,  omentum, 
regie  pubis,  beneath  the  pericardium,  about  the  large 
fessels— especially  the  renal  vessels — in  the  orbit,  etc. 
On  the  other  hand,  there  are  a  few  places  where  fat  is 
oerer  present,  as  for  example  in]  the  lids  and  the  male 
sexual  organs.  The  estimates  of  the  normal  amount  of 
k  in  the  adult  vary  greatly.  Kisch  gives  it  as  one- 
twentieth  the  weight  of  man  and  one-sixteenth  the  weight 
of  woman.  This  normal  amount  reaches  its  height  in 
men  at  the  age  of  forty,  in  women  at  the  age  of  fifty. 

The  influences  which  produce  obesity  are  numerous, 
and  the  endeavor  of  Ebstein  to  reduce  them  in  most 
cases  simply  to  errors  of  diet  and  exercise  will  hardly  suc- 
ceed Obesity  not  unfrequently  attacks  children  before 
puberty,  being  the  expression  of  anaemia,  chlorosis,  faulty 
living  and  heredity.  But  it  is  generally  at  a  later  age 
that  the  trouble  comes  on.  It  is,  no  doubt,  a  fact 
that  a  fuU  diet  containing  an  excess  of  non-nitrogenous 
food,  the  use  of  alcohol,  and  sedentary  habits  are  the 
most  frequent  exciting,  if  not  primary,  causes  of  obesity. 
As  we  have  said  before,  the  question  whether  fat  is  a 
pathogenetic  factor  in  producing  fatness  must,  in  view  of 
Ebitein*s  positive  statements,  remain  for  the  present  un- 
settled. 

Women  are  more  subject  to  obesity  than  men,  a  fact 
that  is  easily  explained  in  view  of  their  more  sedentary 
life,  their  inclination  to  non-nitrogenous  foods,  and  per* 
haps  to  the  lesser  activity  of  their  sexual  life.  For  it 
««ms  quite  certain  that  the  active  exercise  of  the  sexual 
fimction  is  an  element  in  preventing  accumulation  of  fat. 


We  ought  to  mention,  however,  that  Professor  Ebstein 
discredits  this — ^and  the  Professor  has  been  obese  himself 
if  we  are  rightly  informed. 

There  is  a  certain  tendency  to  corpulence  which  is 
racial.  Among  the  English  and  Germans  there  are  more 
fat  men  and  women  than  among  the  Celtic,  Gallic,  Latin, 
or  American  races.  The  Bushmen  and  South  Sea  Isl- 
anders are  inclined  to  take  on  fat,  while  the  North 
American  Indian  is  proverbially  fatless.  In  Mr.  Herbert 
Spencer's  Social  Statics  are  many  interesting  facts  con* 
ceming  this  racial  obesity  or  leanness. 

Most  of  the  stories  regarding  excessively  fat  people 
are  exaggerations.  The  fattest  person  whom  Kisch  has 
ever  seen  weighed  only  385  pounds.  The  celebrated 
Daniel  Lambert  is  credited  with  weighing  52  stone 
II  pounds.  A  man  named  Ed.  Bright  is  quoted  by 
Dr.  Copeland  as  weighing  608  pounds.  Erchenmayer 
cites  the  case  of  a  girl,  ten  years  of  age,  who  weighed  219 
pounds.  Most  of  the  Dime  Museum  £sit  people  weigh 
considerably  under  400  pounds,  and  it  is  very  doubtful 
if  that  limit  is  often  exceeded  by  human  beings  of  ordi- 
nary height. 

According  to  Toldt,  connective-tissue  cells  and  adi- 
pose-tissue cells  are  not  identical.  Toldt  believes  that 
adipose  tissue  is  a  special  fat  organ,  having  a  separate 
and  well-characterized  set  of  blood-vessels  and  an  inde- 
pendent nutrition-process  which  results  in  the  manufac- 
ture of  fat.  Some  physiologists  look  upon  adipose  tissue 
as  a  distinct  metabolic  organ,  and  Toldt's  view  has 
certainly  much  in  its  favor.  According  to  it,  we  must 
suppose  obesity  an  abnormal  activity  on  the  part  of  true 
fatty  tissue,  combined  with  a  morbid  taking  on  of  the  fat- 
making  function  by  ordinary  connective  tissue. 

The  pathological  changes  and  the  consequent  func- 
tional disturbances  in  obesity  are  of  much  interest  Pro- 
fessor Kisch  has  investigated  this  subject,  and  contributes 
some  original  observations  to  it 

First,  as  regards  the  heart,  an  organ  which  is  inclined 
early  to  show  signs  of  disturbed  action.  The  fatty  heart, 
as  distinguished  from  the  fattily  degenerated  heart,  is 
affected,  according  to  Leyden,  in  three  degrees  of 
severity.  In  the  first  there  is  simply  a  thick  layer  of 
adipose  about  the  organ ;  in  the  second,  with  the  fatty 
deposit  there  is  a  softening  or  relaxation  of  the  muscles, 
dilatation  of  the  cavities,  and  enfeeblement  of  action. 
In  the  third  form  there  is  combined  with  the  fatty  heart 
an  arterial  sclerosis.  The  symptoms  in  the  higher  grades 
of  fatty  heart  resemble  considerably  those  of  fatty  de- 
generation, and  need  not  be  here  enumerated.  Kisch 
has  made  sphygmographic  tracings  in  four  hundred  cases 
of  fatty  heart  with  the  following  result :  In  thirty-six  per 
cent  of  cases  there  was  a  pulsus  tardus ;  in  thirty-two 
per  cent  of  cases  the  pulse  varied  from  one  of  a  slightly  to 
one  of  a  completely  dicrotic  character ;  in  twenty-four 
per  cent,  of  cases  an  increase  of  tension  from  arterial 
sclerosis  was  shown ;  in  four  per  cent  of  cases  there 
was  simple  arythmia.  The  value  of  these  examinations 
is,  of  course,  slight  of  themselves.  It  is  to  be  assumed, 
though  it  is  not  stated,  that  the  patients  had  no  valvular 
disease  of  the  heart  and  no  kidney  lesions. 

As  regards  the  respiratory  organs,  Kisch  found  in  many 
cases  bronchial  catarrhs.  Naturally  such  sjrmptoms  as 
dyspnoea,  and  even  pseudo-angina,  were  frequent  9 


184 


THE  MEDICAL  RECORD. 


[August  16,  1884. 


The  digestive  organs  of  the  obese  are  very  likely  to  be 
deranged.  Gastro-intestinal  catarrh,  dyspepsia,  constipa- 
tion, hemorrhoids  are  present,  and  are  due  partly  to 
dietetic  errors,  partly  to  the  weakness  of  the  heart  and 
the  incapacity  or  disinclination  on  the  part  of  the  patient 
to  take  sufficient  exercise.  An  enlarged  and  fatty  liver 
is  of  frequent  occurrence,  but  its  existence  is  not  easy  to 
make  out  by  physical  examination. 

Urates,  uric  acid,  and  oxalate  of  lime  are  found  in  the 
urine.  It  is  well  known  also  that  the  obese  are  liable  to 
glycosuria,  and  Kisch  found  sugar  in  the  urine  of  many  of 
his  patients  at  periodic  or  irregular  intervals. 

Owing  to  the  increased  activity  both  of  the  sweat  and 
the  sebaceous  glands,  fat  persons  are  subject  to  "  catching 
cold"  and  to  attacks  of  rheumatism.  Such  skin  diseases 
as  boils  and  carbuncles  are  relatively  frequent 

The  bodily  temperature  shows  an  inclination  to  mount 
up,  and  in  fevers  the  corpulent  burn  actively.  Their 
feebler  resistance  to  fevers  was  first  pointed  out  by  Hip- 
pocrates. Liebermeister  states  that  they  are  less  amen- 
able to  antipyretic  measures. 

Parallel  with  increase  of  fat  is  a  decrease  of  sexual  ap- 
petite and  sexual  power.  Kisch  found  in  several  cases 
absolute  azoospermia.  Women  are  inclined  to  amenor- 
rhoea  and  sterility.  Among  215  obese  women  Kisch 
found  49  cases  of  amenorrhoea,  119  of  scanty  menstrua^ 
tion,  and  49  of  sterility. 

The  blood  of  the  obese  is  poor  in  red  blood-corpus- 
cles. Obesity  is,  in  fact,  a  disease  of  diminished  and  per- 
verted oxidation.  There  are  not  only  too  few  red  cor- 
puscles, but  there  is  too  much  water  and  an  excess  of  fat. 


THE  EXTRACTION  OF  FOREIGN  BODIES  FROM  THE 
BLADDER. 

As  a  general  rule,  persons  who  have  foreign  bodies  in 
their  bladders  do  not  apply  for  surgical  relief  until  some 
time  has  elapsed.  In  many  cases  this  is  doubtless  due  to 
the  fact  that  they  at  first  suffer  but  little  pain;  after 
a  time,  however,  the  foreign  body  causes  cystitis,  is 
covered  with  layers  of  phosphates,  gradually  increases  in 
size,  and  becomes  a  source  of  constant  irritation  and  dis- 
comfort to  its  host.  The  conditions,  therefore,  of  surgical 
intervention  are  widely  different  according  as  the  foreign 
body  is  recent  or  old.  In  either  case,  extraction  per  vias 
naturales  may  be  very  difficult ;  but  it  is  evident  that  an 
old  foreign  body,  which  has  become  the  nucleus  of  a 
secondary  calculus,  is  peculiarly  interesting  from  the  diffi- 
culties which  it  offers. 

For  a  long  time  it  was  supposed  that  a  lithotomy  oper- 
ation was  imperatively  demanded.  It  is  possible,  how- 
ever, to  remove  it  otherwise  by  two  operations :  At  the 
first  the  calculus  is  crushed  by  the  lithotrite  ;  at  the  sec- 
ond the  foreign  body  is  extracted  in  its  primary  condition. 
Guiard  {Ann.  des  Mai.  Geniio-Urin.^  April,  1884)  has 
recently  removed  a  large  calculus,  the  nucleus  of  which 
was  a  hair-pin,  from  the  female  bladder  by  two  opera- 
tions, with  very  slight  inconvenience  to  the  patient.  And 
Dr.  Heuriet  has  recently  read  a  paper,  before  the  Soci^t^ 
de  Chirurgie,  on  the  application  of  lithotrity  to  foreign- 
body  calculi. 

As  regards  recent  bodies,  their  nature,  consistence, 
and  form  are  of  importance,  and  very  variable;    and 


these  are  especially  difficult  data  to  obtain,  for  the  reason 
that  patients  seem  to  delight  in  deceiving  the  surgeon  in 
all  genito-urinary  matters.  If  the  body  is  flexible,  as  a 
gum  catheter,  it  may  be  cut  or  bent  double  and  drawn 
out,  unless  too  large  for  the  urethra.  If  of  iron  or  wood 
the  lithotrite  is  useless;  if  friable  it  may  be  broken 
up  and  taken  out  piecemeal.  Civiale  recommended  a 
special  instrument  for  cutting  up  the  foreign  body,  and 
then  leaving  its  removal  to  nature.  But  while  this  pro- 
cess might  be  successful  in  some  instances,  there  are  too 
many  probabilities  that  some  of  the  pieces  may  renudn 
to  give  further  trouble. 

Removal  per  urethram^  then,  while  often  difficult, 
merits,  by  reason  of  its  great  importance,  serious  atten- 
tion. The  surgeon  should  know  in  what  part  of  the 
bladder  the  body  is  situated,  and  in  what  position  he  can 
secure  it.  Heuriet  has  shown  by  actual  experiment  upon 
the  cadaver,  that  these  foreign  bodies  are  governed  by 
what  he  calls  laws  of  accommodation,  as  is  the  foetus  in 
utero,  with,  of  course,  the  exception  of  rounded  bodies. 
From  his  experiments  Heuriet  drew  the  following  con- 
clusions :  I.  The  transverse  diameter  of  the  bladder  is  the 
most  constant ;  it  is  the  only  diameter  which  persists  when 
the  viscus  is  completely  empty,  and  which,  in  that  state, 
furnishes  a  resting-place  for  foreign  bodies,  provided  they 
are  not  above  a  certain  size.  2.  As  the  bladder  becomes 
distended,  other  diameters  are  formed  and  it  tends  to  be- 
come spherical.  Its  transverse  diameter  then  attains  its 
maximum,  which  is  10  ctm.  or  more  (4  inches).  Its  ver- 
tical diameter  continues  to  increase  and  may  attain 
excessive  dimensions.  3.  The  maximuw  of  the  trans- 
verse diameter  is  almost  at  an  equal  distance  from  the 
summit  of  the  bladder,  whatever  may  be  its  development, 
and  the  cervical  region  perhaps  a  little  nearer  to  the 
latter.  4.  Foreign  bodies,  quite  rigid,  and  12  ctm.  (4.2 
inches)  long,  can  only  lodge  completely  in  a  distended 
bladder,  and  in  a  vertical  or  oblique  diameter.  5.  Bodies 
6  or  8  ctm.  (2.4  to  3.2  inches)  long  generally  assume  a 
transverse  position.  It  is  only  when  the  bladder  is  full  and 
considerably  distended  that  they  may  take  a  vertical  or 
oblique  position,  or  rest  on  one  extremity  in  the  region 
of  the  neck.  When  they  have  a  transverse  position  they 
may  float,  provided  their  specific  gravity  and  the  amount 
of  vesical  dilatation  permit ;  but  hollow  bodies,  such  as 
a  piece  of  catheter,  almost  always  remain  at  the  base. 

The  transverse  diameter,  therefore,  is  that  which  varies 
least,  whatever  may  be  the  state  of  distention  of  the 
bladder,  being  smallest  when  the  bladder  is  distended 
and  greatest  when  it  is  empty.  These  peculiarities  have 
a  remarkable  influence  on  the  direction  which  foreign 
bodies  take,  and  we  know  a  priori  that  they  tend  to  as- 
sume a  transverse  position.  On  entering  the  bladder 
from  the  urethra  they  are  situated  in  an  antero-posterior 
median  plane.  But  after  micturition  the  antero-posterior 
and  vertical  diameters  are  effaced,  and  the  body  changes 
its  position  ;  its  posterior  extremity  receives  an  impulse 
from  the  corresponding  wall  of  the  bladder  which  tends 
to  approach  the  neck.  This  impulse  moves  the  anterior 
extremity  from  the  median  line,  where  it  was  at  first,  to- 
ward the  right  or  left,  on  account  of  the  persistence  of 
the  transverse  diameter.  At  the  same  time,  as  the 
bladder  contracts,  the  posterior  extremity  is  pushed  for- 
ward by  the  diminution   of  the  antero-posterior,  and 


August  i6,  1884.] 


THE  MEDICAL  RECORD. 


185 


downward,  by  the  diminution  of  th^  vertical  diameter. 
Thus  the  transverse  diameter  is  the  only  one  which  the 
body  can  assume  when  the  bladder  is  empty.  It  may, 
therefore,  be  laid  down  as  a  rule  that  ri^id  and  elongated 
foreign  bodies  tend  to  assume  a  transverse  position.  But 
if  their  dimensions  exceed  6  or  8  ctm.  they  cannot  rest 
in  this  position,  but  must  lie  obliquely. 

Those  accustomed  to  vesical  manipulations  know  that 
the  contractions  of  this  organ  commence  by  a  raising  up 
of  the  posterior  face  and  floor.  These  parts  seem  to 
advance  toward  the  neck,  leaving  two  prolongations  on 
each  side,  which  subsequently  approach  the  neck.  The 
neck  is  the  fixed  point  and  all  other  parts  contract  to- 
ward it,  and  the  diminution  of  the  capacity  of  the 
bladder  commences  by  shortening  of  the  antero-posterior 

I  diameter,  which  is  followed  by  shortening  of  the  vertical 
diameter. 

I  The  elevation  of  the  floor  of  the  bladder  is  a  very 
essential  point  in  enabling  the  surgeon  to  grasp  a  frag- 
ment In  cases  of  enlarged  prostate  great  difficulty 
may  be  encountered  until  the  bladder  commences  to  con- 
tract, raising  the  base  and  thus  bringing  the  body  within 
reach  of  the  instrument.  In  searching  for  a  body  in  an 
empty  bladder,  it  may  be  impossible  to  move  the  instru- 
ment save  in  a  lateral  direction,  and  if  this  cannot  be 
done  the  operator  may  be  sure  that  the  bladder  has  not 
been  entered.  When,  however,  the  bladder  is  distended, 
as  by  an  injection,  these  conditions  immediately  change. 
The  foreign  body  becomes  movable,  and  its  position  is 
no  longer  regulated  by  physiological  but  by  physical 
laws.  The  case  is  analogous  to  the  state  of  hydramnios 
in  the  pregnant  woman.  The  foetus  simply  floats  about 
and  has  not  stable  position.  Distention  of  the  bladder 
by  injection,  therefore,  so  far  from  favoring  the  search 
for  and  extraction  of  the  body,  really  hinders  these 
manceuvres. 

Life  ! — Dr.  S.  W.  Francis'  latest  definition  is — Can  : 
Can^Can:  Can't  I 

The  American  Dental  Association  held  its  annual 
meeting  in  Saratoga  last  week. 

Quarantine  at  New  Orleans  has  been  reduced 
from  forty  to  ten  days  for  ships  from  infected  ports. 

The  State  Board  of  Health  of  Kentucky  has  is- 
soed  a  circular  of  instructions  regarding  the  prevention 
of  cholera. 

Fatal  Accident  to  a  Medical  Student. — Another 
filial  accident  has  occurred  in  the  Alps,  the  victim  being 
a  medical  student,  son  of  Professor  Bamberger,  of 
Vienna. 

Another  Grave-robberv  near  Philadelphia. — 
Two  men,  one  of  them  a  Dr.  J.  B.  Welder,  of  Philadel- 
phia, have  recently  been  arrested  for  grave-robbery  at 
Norristown. 

^  Popularity  of  the  London  Health  Exhibition. — 
Upward  of  one  and  a-half  million  have  visited  the  Inter- 
national Health  Exhibition  during  the  two  months  it  has 
been  open  to  the  public. 


Lepers  Returned  to  China. — ^The  authorities  of 
the  city  of  San  Francisco  have  sent  back  to  China  nine- 
teen Chinese  lepers,  paying  their  passage  and  giving  each 
one  $5.     Nineteen  cases  lost  to  science. 

The  Cholera  in  the  United  States. — The  proba- 
bilities are  that  the  present  European  epidemic  will  not 
be  a  severe  one,  and  that  the  cholera  will  not  reach  this 
country  until  next  spring  or  summer. 

Jefferson  Medical  College. — Dr.  Robert  £. 
Rogers,  Professor  of  Medical  Chemistry  and  Toxicology 
in  this  institution,  has  tendered  his  resignation  of  the 
chair,  to  which  he  was  elected  in  1877. 

An  Italian  Doctress. — Fraulein  Giuseppina  Cat- 
tani  has  recently  passed  her  medical  examination  at  the 
University  of  Bologna  cum  laude.  Miss  Josephine  is  a 
pioneer  among  Italian  medical  women. 

A  Dangerous  Project. — A  St.  Louis  physician  pro- 
poses to  publish  an  '*  Encyclopaedia  of  Medical  Wit  and 
Humor."  We  earnestly  urge  our  respected  and  ambi- 
tious confrere  to  make  it  a  pocket  edition. 

An  Austrian  Cholera  Commission. — The  authori- 
ties of  Vienna  have  sent  a  commission  composed  of  two 
physicians  and  three  sanitarians  to  Toulon  and  Mar- 
seilles for  the  purpose  of  investigating  the  cholera  epi- 
demic. 

Massachusetts  General  Hospital.  —  TTie  Boston 
Medical  and  Surgical  Joumctl  is  '^  glad  to  state  that  at  the 
request  of  the  Board  of  Trustees,  Drs.  H.  J.  Bigelow 
and  R.  M.  Hodges  have  withdrawn  their  resignations 
from  the  staff  of  visiting  surgeons." 

The  Successor  of  Dr.  Wm.  Pepper. — The  Medical 
News  states  that  Dr.  William  Osier,  of  McGill  Univer- 
sity, Montreal,  is  favorably  mentioned  in  connection  with 
the  Professorship  of  Clinical  Medicine  in  the  University 
of  Pennsylvania,  lately  held  by  Prof.  Pepper. 

An  Ancient  Hospital  Confiscated. — The  Hospital 
of  Jesus  in  the  City  of  Mexico  is  said  to  have  been  founded 
and  endowed  by  the  conqueror  Cortez.  The  government 
has  recently  confiscated  the  property  on  the  plea  that  the 
terms  of  the  founder's  will  had  not  been  complied  with. 

Pasteur's  Hydrophobia  Vaccine  a  Success. — ^The 
government  commission  which  has  been  making  experi- 
ments similar  to  those  of  M.  Pasteur  in  connection  with 
finding  a  preventive  for  hydrophobia,  has  reported  tliat 
its  investigations  decisively  confirm  the  correctness  of 
the  distinguished  scientist's  theory. 

Living  Quadruplets. — An  apparently  authentic  ac- 
count is  given  of  the  birth  of  four  living  male  children 
by  a  woman  named  Mrs.  H.  W.  Pullman,  who  resides 
near  Eureka,  Mo.  The  mother  had  previously  given 
birth  to  triplets,  and  the  husband  may  well  look  forward 
to  the  next  pregnancy  with  interest. 

Hydrochinon — Another  Antipyretic. — Dr.  Paul 
Seifert  reports  upon  the  antipyretic  value  of  hydrochinon, 
C,H,0„  a  benzol-compound  resembling  resorcin.  He 
finds  that  it  reduces  temperature  as  quickly  though  not 
quite  so  permanently  as  quinine.  It  has  no  irritative  or 
toxic  effects.     The  dose  varies  from  one  to  four  grammes. 


1 86 


THE  MEDICAL  RECORD. 


[August  i6, 1884, 


The  Carnegie  Laboratory  at  Bellevue  Hospital 
-Medical  College.— Plans  for  the  erection  of  this  new 
laboratory  have  been  filed  and  work  upon  it  will  soon 
be  begun.  The  building  will  be  fifty  feet  square,  and 
five  stories  high.  It  will  be  on  East  Twenty-sixth  Street, 
on  the  south  or  opposite  side  from  the  present  College 
Building. 

That  Office  Thief. — Our  warning  of  last  week  came 
too  late  to  prevent  the  robbing  of  Dr.  Francis  J.  Quin- 
tan's office  in  West  Fifteenth  Street.  Dr.  Quinlan  was 
robbed  of  clothing,  valuable  books,  and  surgical  instru- 
ments. One  of  the  most  aggravating  things  in  connection 
with  these  robberies  is  the  stupidity  and  inefficiency  of  the 
city's  detective  force.  We  have  yet  to  learn  of  any  case 
in  which  they  have  done  anything  but  look  "devilish  sly.'* 

What  Cholera  has  done  for  Russia.— Cholera  first 
appeared  in  European  Russia  in  1823,  says  the  Nowoje 
Wremja^  and  continued  until  1838.  During  this  time 
500,000  persons  were  attacked,  and  240,000  died  (43 
per  cent.).  In  the  second  epidemic  (1847-59),  out  of 
2,589,000  attacked,  1,032,000  died  (40  per  cent.).  In 
the  next  epidemic  (1865-72)  there  were  326,968  deaths. 
Altogether  cholera  has  attacked  4,000,000,  and  killed 
[,600,000  Russians. 

Specific  Directions  for  Preventing  Cholera. — 
The  five  points  to  be  looked  after  in  attempts  to  prevent 
cholera,  as  laid  down  by  the  Illinois  Board  of  Health, 
are  :  i.  The  condition  of  the  water  supply;  2.  The  dis- 
position of  night-soil,  garbage,  and  sewage;  3.  The 
cleansing  of  streets,  alleys,  and  other  public  places ;  4. 
The  supervision  of  food  supplies,  and  of  market-places, 
«laughter-houses,  and  similar  establishments ;  5.  The  gen- 
eral sanitation  of  every  house  and  its  surroundings. 

The  Cincinnati  Board  of  Health. — Our  valued 
contemporary  the  Cincinnati  Lancet  and  Clinic  has  for 
some  time  been  trying  to  awaken  the  profession  to  an 
interest  in  reforming  the  sanitary  management  of  the  city 
of  Cincinnati.  A  year  ago  the  Cincinnati  Board  of  Health 
was  constituted  of  five  saloon  keepers  and  one  quack 
doctor,  now  it  has  reformed  enough  to  substitute  a  street 
paver  for  the  quack.  The  medical  profession  is,  how- 
ever, still  not  represented  at  all  in  the  sanitary  councils 
of  the  city.  This  is  certainly  a  very  anomalous  condition 
of  afifairs  and  we  trust  that  the  Lancet  and  Clinic  will 
keep  at  work  until  some  improvement  is  brought  about. 

Water  and  Disease — Sanitary  HvdroI»hobia. — 
The  following  two  items  have  recently  been  put  in  cir- 
culation. The  tendency  of  modern  sanitation  is  appar- 
ently to  make  people  afraid  of  water,  creating  a  kind  of 
sanitary  hydrophobia :  "  Of  142  epidemics  of  typhoid  fever, 
observed  in  various  localities,  in  125  cases  the  epidemic 
had  no  other  determining  cause  than  the  use  of  water 
containing  impurities "  (**  Reports  Local  Government 
Board,  England  ").  "  If  any  taint  (however  small)  of  in- 
fective material  gets  access  to  wells  or  other  sources  of 
drinking-water,  it  imparts  to  large  volumes  of  water  the 
power  of  propagating  disease  "  ("  Mem.  Local  Govern- 
ment Board,  England,  July  13,  1883  "). 

The  Epidemiological  Society  of  London  held  a 
conference  on  July  2  2d.  The  president  of  the  society. 
Dr.  Norman  Chevers,  C.I.E.,  opened  the  meeting  with 


an  address  entitled  ''  Health  in  India,"  and  was  followed 
by  Dr.  William  Squire  on  "  Change  in  Type  of  Epidemic 
Disease."  The  conference  was  concluded  July  23(1^ 
when  ah  all-day  sitting  was  held.  The  subjects  treated 
were  ''  Leprosy  in  India  and  the  Best  Means  of  P^eveQ^ 
ing  its  Increase,"  by  Surgeon-Major  Pringle,  M.D. ;  "The 
Behavior  of  Typhus  in  England  during  the  Present  Cen- 
tury;'* and  "A  Consideration  of  the  Present  Aspect  of 
Cholera  in  Europe."  The  latter  subject  was  opened  by 
Dr.  Lawson,  Inspector-General  of  Hospitals,  and  excited 
warm  discussion  among  a  number  of  medical  gentlemen 
who  were  present. 

A  Discussion  on  Germ-Pathology  and  Cholera 
took  place  at  the  monthly  meeting  of  the  Newport  Medi- 
cal Society,  August  5th.  A  number  of  New  York  and 
Boston  physicians  took  part,  including  Drs.  W.  T.  Lusk, 
Leroy  Satterlee,  and  Dr.  H.  O.  Marcy.  The  latter  gen- 
tleman read  a  paper  on  the  relations  of  micro-organisms 
to  infectious  diseases.  He  referred  to  the  apparent  con- 
tradiction between  Florence  Nightingale,  in  her  communi- 
cations to  the  New  York  Herald^  and  Dr.  Koch,  in  his 
official  letter  to  the  Mayor  of  Toulon,  the  one  of  whom 
claims  that  personal  contact  with  cholera  was  not  to  be 
feared,  while  the  other  strenuously  condemns  the  possi- 
bility of  even  the  slightest  risk  of  personal  contagion. 
Dr.  M.  argued  that  the  true  safety  lay  in  the  mean  be- 
tween the  two  extremes  of  opinion,  and  that  constant 
and  perfect  sanitation,  with  avoidance  of  both  direct  and 
indirect  exposure  to  the  disease  were  required. 

An  Attorney-General  who  Understands  Blood- 
PuRiFiERS. — Time  was,  says  The  Medical  Chronicle^  when 
a  gentleman  holding  in  this  State  the  exalted  office  of 
Attorney-General,  had  too  nice  a  sense  of  the  proprieties 
of  his  position  to  descend  to  recommend,  in,  his  offidal 
capacity,  a  quack  preparation,  as  is  done  in  the  following 
communication,  which  is  being  extensively  advertised  in 
the  newspapers:  "The  State  of  Maryland,  Office  of 
Attorney-General,  Westminster,  Md.,  April  28,  1884. 
Charles  C.  F.  Schroeder,  Esq.:  Dear  Sir — I  am  personally 
well  acquainted  with  Dr.  J.  W.  Steele  and  Dr.  Wm.  M. 
Hines.  They  are  practising  physicians  of  this  county, 
of  excellent  standing  and  large  experience,  and  thor- 
oughly competent  to  speak  as  to  the  merits  of  your  Iron 
Tonic  and  Blood  Purifier.  Very  truly  yours,  Charles 
B.  Roberts."  Our  contemporary  very  justly  protests 
against  the  prostitution  of  the  Attorney-General's  office 
to  any  such  business  as  the  above. 

Cholera  and  the  Acad6mib  de  MAdecine. — At  the 
session  of  the  Academic  de  M6decine  July  2 2d,  a  letter 
from  M.  Fauvel  was  read,  in  which  he  adhered  to  and  de- 
fended his  view  that  the  cholera  at  Toulon  and  Marseilles 
was  not  Asiatic  and  not  contagious.  M.  Fauvel's  views 
may  safely  be  considered  the  expressions  of  obstinate 
senility. 

M.  Jules  Gu6rin  delivered  an  address  on  cholera  which 
was  eloquent  and  interesting,  though  in  some  regards 
rather  antiquated.  M.  Gu6rin  talked  of  "  epidemic  con- 
stitutions," atmospheric  and  organic  influences,  and  the 
evolution  of  epidemics  under  certain  fixed  laws.  He 
thought  the  contagiousness  of  cholera  a  secondary  matter, 
denounced  quarantine,  and  commended  the  English 
m  ethod  of  inspection. 


August  i6,  1884.] 


THE  MEDICAL  RECORD. 


187 


Progress  of  the  Cholera. — A  temporary  increase 
in  the  number  of  cases  of  cholera  at  Toulon  and  Mar- 
seilles occurred  during  the  latter  part  of  last  week  owing 
to  the  intense  heat  and  the  return  of  many  fugitives.    On 
the  whole,  however,  the  violence  of  the  disease  has  greatly 
abated  in  the  cities  mentioned     The  number  of  deaths 
occuning  daily  has  rarely  exceeded  four  or  five  at  Toulon 
and  fourteen  at  Marseilles.     On  the  other  hand  the  dis- 
ease has  undoubtedly  gained  a  firm  hold  in  Southern 
France  and  Northern  Italy.     Many  small  towns  have 
been  attacked  with  great  violence.     Thus  says  a  Times 
correspondent :     "  In  the  little  village  of  Gignac,  near 
Montpellier,  forty  cases  of  cholera  have  been  found,  and 
there  have  been  numerous  deaths.     The  panic  there  was 
so  terrible  that  the  fathers  and  mothers  of  families  fled, 
leaving  their  little  children  uncared  for.     At  Vogue,  a 
village  of  less  than  eight  hundred  souls,  in  the  Arddche, 
over  thirty  cases,  with  seven  deaths  in  the  twenty-four 
hours  have  occurred.     An  outbreak  of  cholera  in  Algiers 
is  feared.     Some  of  the  reports  of  deaths  firom  cholera  in 
the  villages  near  Toulon  are  particularly  heart-rending. 
In  some  of  them  more  people  died  of  cholera  in  a  day 
than  in  Toulon  during  the  same  twenty-four  hours.     In 
Bordeaux  there  have  been  three  deaths.'' 

Reports .  state  that  examinations  of  the  water  firom 
the  wells  and  fountains  in  all  the  places  visited  by  cholera 
show  the  presence  of  vast  numbers  of  microbes. 

The  English  cholera  (cholera  nostras)  has  broken  out 
seriously  at  Northampton  and  in  villages  near  Blackburn. 
Over  two  hundred  were  reported  sick  at  one  time. 

So  far  as  the  mortality  of  the  disease  is  concerned,  the 
statistics  of  the  Pharo  Hospital,  Marseilles,  are  instruc- 
tive. These  statistics  show  that  521  cases  of  cholera 
have  been  admitted,  of  which  313  ended  fatally,  or  about 
do  per  cent.  This  b  a  high  mortality  rate  for  the  disease. 
A  number  of  changes  have  been  made  in  the  various 
quarantine  regulations :  Spain  has  established  a  ten  days 
quarantine  against  infected  Italian  ports.  The  Belgian 
Government  has  quarantined  against  all  Mediterranean 
ports.  At  the  port  of  New  York,  the  Health  Officer 
has  issued  some  further  regulations.  Vessels  on  which 
cholera  develops  during  the  voyage  to  this  port  will,  of 
coarse,  be  detained,  the  sick  removed  to  the  hospital, 
and  the  well  persons  to  the  Quarantine  of  Observation. 
Any  cargo  of  which  there  is  any  suspicion  will  be  dis- 
charged in  Quarantine.  The  baggage  of  passengers  from 
an  infected  district,  or  section  of  country  bordering  there- 
on, is  required  of  captains  to  be  kept  separate  firom 
other  baggage.  Vessels  discharging  in  Quarantine  will 
be  thoroughly  disinfected  before  being  allowed  to  come 
up  to  the  city.  The  same  rules  will  apply  to  baggage  or 
cargo  shipped  from  an  infected  to  a  healthy  port  and  re- 
shipped  here.  Vessels  with  cargoes  wholly  or  in  part  of 
tags  will  not  be  given  pradque  if  coming  from  infected 
ports,  and  if  from  healthy  ports,  satisfactory  evidence 
that  they  have  not  been  reshipped  firom  infected  districts 
win  be  required,  as  well  as  evidence  that  they  have  been 
collected  where  no  suspicion  of  cholera  exists. 

Cheap  Quinine. — Physicians  should  know  that  qui- 
nine is  steadily  decreasing  in  price,  and  has  lately  been 
sold  as  low  as  $1  an  ounce.  It  is  poor  policy,  therefore, 
to  use  the  so-called  ''  cheaper  alkaloids  "  when  quinine, 
which  is  more  efficient,  costs  but  little  more.    The  cause 


of  the  decline  in  price  is  said  to  be  the  removal  of  the 
tariff,  and  an  over-production  on  the  part  of  foreign  manu- 
facturers. The  world's  production  to-day  is  estimated  at 
4,500,000  ounces,  of  which  Germany  and  Italy  manufac- 
ture by  far  the  greatest  portion.  There  is  considerable 
made  in  England,  but  this  is  of  a  superior  quality,  and 
its  enhanced  cost  limits  its  consumption  and  consequent 
production.  America  consumed  forty  per  cent,  of  the  to- 
tal production,  or  about  1,800,000  ounces.  Prior  to  the  re- 
moval of  the  tariff,  1,500,000  ounces  were  produced  here, 
but  the  effect  of  the  removal  of  the  duty  has  been  to  de- 
crease the  manufacture  and  make  the  United  States  more 
dependent  upon  foreign  supplies.  It  is  estimated  that 
now  not  more  than  1,000,000  ounces  are  manufactured 
in  the  New  World,  but  this  is  in  part  due  to  the  destruc- 
tion by  fire,  in  Philadelphia,  of  the  works  of  the  largest 
American  producers,  who  now  send  their  bark  to  Europe 
to  be  prepared  for  the  market.  From  the  East  Indies 
the  shipments  of  the  raw  material  to  the  United  States 
were  over  6,000,000  pounds,  of  which  a  very  large  pro- 
portion was  shipped  to  Europe  for  account  of  the  Amer- 
ican manufacturers.  Of  late  years  the  quality  of  the 
product  has  materially  improved,  the  quinine  now  sold 
having  not  more  than  from  two  to  five  per  cent,  of  the 
lower  alkaloids,  while  it  is  but  a  short  time  since  that 
quinine  having  ten  per  cent  of  these  was  deemed  a  satis- 
factory article.  This  improvement  is  believed  to  be  due 
entirely  to  the  better  quality  of  the  bark  obtained  from 
the  cultivated  tree. 


EIGHTH   SESSION, 
Held  at  Copenhagen^  Denmark^  August  10-16,  1884. 


BY  CABLE  TO  THE  MEDICAL  RECORD. 


Sunday,  August  ioth — First  Day. 

The  eighth  annual  session  of  the  International  Medical 
Congress  was  formally  opened  on  Sunday,  August  loth, 
by  Professor  Panum,  of  Copenhagen,  who  delivered 
the  following 

ADDRESS   OF   WELCOME. 

After  thanking  the  King  and  Queen  of  Denmark,  the 
King  and  Queen  of  Greece,  and  the  State  Council,  he 
expressed  his  great  gratification  at  the  large  audience 
present,  and  hoped  that  the  present  session  of  the  Con- 
gress would  tend  to  advance  the  science  of  medicine, 
and  that  a  broad  and  liberal  spirit,  becoming  the  grand 
object  in  view,  would  characterize  all  its  deliberations. 

Sir  James  Paget  followed  with  a  brilliant  address,  in 
which  he  thanked  Denmark  on  behalf  of  Great  Britain 
for  its  gift  of  a  princess  who  was  a  model  prince's  wife. 
He  concluded  by  hoping  that  the  present  Congress  would 
be  equally  successful  with  that  held  in  London. 

Professor  Virchow,  in  behalf  of  Germany,  hoped  that 
the  Congress  would  honor  that  country  by  its  choice  for 
a  fiiture  meeting. 

Professor  Pasteur  also  addressed  the  Congress  in 
some  general  remarks,  in  which  he  referred  to  the  cos* 


i88 


THE   MEDICAL  RECORD. 


[August  i6,  1884. 


mopolitan  character  of  science,  and  the  impossibility  of 
conforming  it  to  any  particular  country. 

The  King  and  Queen  of  Denmark,  Council  of  State, 
and  King  and  Queen  of  Greece  were  present.  Sixteen 
hundred  members  were  in  attendance ;  of  these  eleven 
hundred  were  foreigners,  including  one  hundred  English- 
men and  about  fifty  Americans. 

In  the  evening 

A  GRAND    BANQUET 

was  tendered  the  members.     It  was  largely  attended. 


Monday,  August  hth — Second  Day. 

The  Congress  in  its  general  session  to-day  listened  to 
the  address  of  Professor  Pasteur,  of  Paris,  on 

MORBIFIC  micro-organisms   AND   VACCINIA   MATTERS. 

He  described  his  different  well-known  experiments  in 
the  inoculation  of  rabies  by  injecting  the  virus  into 
the  veins  of  dogs,  and  the  results  in  protection  against 
the  evil  effects  of  the  bites  of  rabid  animals.  He  referred 
to  the  report  of  the  French  Government  Commission  ap- 
pointed to  investigate  hydrophobia,  stating  that  twenty- 
three  dogs  had  been  experimented  upon  by  protection. 
All  had  been  bitten  by  rabid  animals  in  June  last,  and 
yet  all  had  remained  healthy.  Of  nineteen  unprotected 
animals,  similarly  bitten,  fifteen  went  mad.  It  was  the 
intention  of  the  Government  Commission  to  repeat  these 
experiments.  In  closing  he  emphasized  the  necessity  of 
attempting  to  protect  animals  only,  but  if  the  dogs  were 
protected  the  disease  would  be  exterminated. 

At  the  meetings  of  the  sections,  sixteen  in  number,  the 
different  Presidents  delivered  their  addresses. 

meetings   of   SECTIONS. 

Section  on  Anatomy, — Papers  read  :  "  The  Glandular 
Cells  during  Activity,"  by  Professor  Ranvier,  of  Paris  ; 
"Terminations  of  Sensitive  Cutaneous  Nerves,"  by  Pro- 
fessor Merkel,  of  Konigsberg ;  "  Rotary' Movements  of 
Forearm,"  by  Professor  J.  Herberg,  of  Christiana. 

Section  on  Physiology. — Papers  read  :  "  Mucous  and 
Albuminous  Matters,"  by  Dr.  Hammarsten,  of  Upsala  ; 
"  Fugitive  Corpuscles,"  by  Dr.  R.  Norris,  of  Birmingham  ; 
"Coagulation  of  Blood,"  by  Dr.  Wooldridge,  of  Cam- 
bridge  ;  "  Oxyhaemoglobin,"  by  Dr.  C.  Bohr,  of  Copen- 
hagen ;  "  Glandular  Cells,"  by  Dr.  Langley,  of  Cam- 
bridge ;  "  Functions  of  Cutaneous  Nerves,"  by  Dr.  Blix, 
of  Upsala. 

Section  on  Pathology. — Papers  read  :  "  Necrosis  of 
Coagulation,"  by  Professor  Weigert,  of  Leipsic ;  "  Bac- 
terial Inflammation,"  by  Professor  Cornil,  of  Paris ;  "  Je- 
quirity,"  by  Dr.  C.  J.  Salomousen,  Copenhagen. 

Section  on  Medicine, — Papers  read  :  "  On  Uniform 
Nomenclature  of  Auscultatory  Signs  in  the  Diagnosis  of 
Diseases  of  the  Chest,"  by  Professor  Austin  Flint,  of  New 
York ;  "  The  Blood-Corpuscles  in  Anaemic  and  Leucae- 
mic  Diseases,"  by  Dr.  S.  Laache,  of  Christiana. 

Section  on  Surgery,  —  Papers  read  :  "  The  Iodoform 
Treatment,"  by  Professor  Mosetig-Moorhof,  of  Vienna; 
On  Antiseptics— "The  Sublimate  Treatment,"  by  Dr.  M. 
Schede,  of  Hamburg ;  "  The  Treatment  by  Oxygenated 
Water,"  by  Professor  Paul  Bert,  of  Paris;  "Permanent 
Antiseptic  Dressing,"  by  Professor  Esmarch^  of  Kiel ; 


"  Anaesthetics  in  Surgery,"  by  Professor  Bert,  of  Pans  • 
"  Colotomy,"  by  Professor  Bryant,  of  London. 

Section  on  Obstetrics. — Papers  read  :  "  Myomata  Uteri 
by  Laparotomy,"  by  Professor  Koeberle,  of  Strasburg ; 
"Supra- Vaginal  Amputation,"  by  Dr.  Margary,  of  Turin; 
"  Caesarean  Section,'*  by  Professor  P.  Miller,  of  Berne, 
and  Professor  Eustache,  of  Lille. 

Section  on  Laryngology. — Papers  read  :  "  The  Prog, 
nostic  Significance  of  the  Several  Local  Manifestarions 
Observed  in  Tuberculosis  of  Larynx,"  by  Dr.  J.  Solis 
Cohen,  of  Philadelphia. 

Section  on  State  Medicine. — Papers  read:  "School 
Hygiene  in  Denmark,"  by  Professors  Hertel,  of  Copen- 
hagen, and  Key  of  Stockholm,  and  Mr.  Holbech,  of 
Copenhagen. 

TuEspAY,  August  i2TH — ^Third  Day. 
At  the  general  session  to-day  the  address 

ON    THE    NATURAL    PRODUCTION    OF    MALARIA    AND    THK 
MEANS   OF   MAKING   MALARIAL   COUNTRIES    HEALTHIER, 

was  delivered  by  Tommasi  Crudeli,  of  Rome.  (See  next 
number  of  The  Medical  Record.) 

INVITATION    for   CONGRESS    IN    AMERICA. 

A  communication  was  received  from  Dr.  Billings,  ou 
behalf  of  the  American  Medical  Association,  inviting  the 
Congress  to  hold  its  next  session  in  Washington,  U.  S. 

the  work  in  the  sections. 

In  the  Section  on  Pathology^  Professor  Grancher,  of 
Paris,  read  a  paper  on  "  The  Relations  of  Scrofulosis  and 
Tuberculosis,"  and  Professor  Roquemondane,  of  Limoges, 
remarked  on  Ixodes,  an  almost  unknown  human  para- 
site. 

Section  on  Medicine, — Professors  Ewald,  of  Berlin,  Jac- 
coud  and  Grancher,  of  Paris,  presented  the  subject  of 
**  Tuberculosis  in  its  Different  Relations  to  Etiology  and 
Pathology.'' 

Section  on  Surgery. — Dr.  Lewis  A.  Sayre,  of  New 
York,  exhibited  his  plaster-of-Paris  jacket,  and  demon- 
strated its  application.  Professor  Oilier,  of  Lyon,  read  a 
paper  on  "  Excision  and  Orthrotomy  in  Tuberculous  Joint 
Diseases,"  and  Professor  MacEwen,  of  Glasgow,  Scot- 
land, presented  the  subject  of  "  Orthopedic  Osteotomy 
for  Genu  Valgum  and  Club-foot." 

Section  on  Obstetrics, — Professor  Mikulicz,  of  Cra- 
kow,  read  a  paper  on  "Antiseptics  in  Laparotomy."  Pro- 
fessor Simpson,  of  Edinburgh,  also  read  a  paper  on  '*  An 
International  Nomenclature  in  Obstetrics,"  and  Professor 
Halberstma,  of  Utrecht,  on  "  The  Significance  of  Albu- 
minuria in  Pregnant  Women." 

Section  on  Ophthalmology, — ^The  following  papers  were 
read :  Dr.  Redard,  of  Paris,  "  On  the  Examination  of 
Vision  of  Railway  Employees  ;  "  Professor  Rachlmann, 
of  Dorpat,  on  "Trachoma;"  Professor  Sattler,  of  Er- 
langen,  on  "  The  Anatomy  of  Ciliary  Muscle." 


Wednesday,  August  13TH — Fourth  Day. 

This  day  was  devoted  to  excursions  in  steamers,  which 
included  one  to  the  tomb  of  Hamlet  at  Elsinore. 


i 


August  i6>  1884.] 


THE  MEDICAL  RECORD. 


189 


Reports  at  SacUtUs. 


NEW  YORK  PATHOLOGICAL  SOCIETY. 

Stated  Meeting y  June  25,  1884. 

Frank  Ferguson,  M.D.,  President,  pro  tern. 

Dr.  Ferguson  reported  on  the  specimens  presented 
by  Dr.  Wackerhagen  at  the  last  stated  meeting. 

Dr.  J.  H.  Ripley  presented,  on  behalf  of  a  candidate, 
a  specimen  of  Phihisicat  Ulceration  of  the  Larynx. 

Dr.  C.  H.  Knight  presented  specimens  of 

;  NASAL  POLYPI, 

removed  from  a  patient  who  gave  a  history  of  nasal  ca- 

tanfa^of  four  years'  standing,  frontal  headache,  loss  of 
smell,  and,  for  the  last  six  weeks,  complete  obstruction 
of  the  meatus. 

The  interesting  point  in  the  clinical  history  was  with 
rq;ard  to  the  occurrence  of  asthma.  There  was  no  evi- 
dence, on  physical  examination  of  the  chest,  of  pulmo- 
nary disease.  Removal  of  the  pol}'pi  had  given  the  pa^ 
dent  relief. 

Dr.  W.  M.  Carpenter  referred  to  hypertrophy  of  the 
nasal  mucous  membrane  as  an  etiological  factor  in  hay 
fever,  to  which  attention  had  been  directed  by  Dr.  Roe, 
of  Rochester,  and  Dr.  Sajons,  of  Philadelphia,  and 
others. 

Dr.  Knight  remarked  that  the  sjrmptoms  in  his  case 
were  those  of  asthma,  rather  than  hay  fever,  and  that  the 
I^tient  had  not  been  a  sufiferer  from  the  periodical  a£fec- 
tion  known  as  hay  asthma  or  hay  fever. 

Dr.  Ripley  remarked  that  the  tendency  was  toward 
&e  production  of  emphysema  when  there  was  obstruc- 
tioQ  to  the  entrance  of  air  into  the  air-vesicles. 

Dr.  Knight  remarked  that  probably  the  condition 
of  obstruction,  in  his  case,  had  not  existed  sufficiently 
long  to  produce  emphysema ;  at  least  there  was  no  cvi- 
dence  of  its  existence  on  physical  examination. 

Dr.  H.  N.  Heineman  presented  a  specimen  illustrat- 
ing 

general  tuberculosis. 

Patient,  aged  seven  months,  was  admitted  to  Mount 
Sinai  Hospital  June  7,  1884.  Father  has  phthisis.  Up 
to  five  weeks  ago  had  been  well.  Then  mother  noticed 
frequent  chilly  appearance,  but  got  better.  For  the  past 
four  weeks  has  been  unusually  quiet,  and  rolled  its  head. 
Three  weeks  ago  had  slight  convulsive  seizures,  and  for 
sometime  frequent  stools  with  straining;  urine  dimin- 
ishcd  in  quantity. 

On  admission  there  was  frequent  respiration,  cyanosis, 
twitchmgs  of  both  arms  (chiefly  the  left),  and  a  hydro- 
cq)halic  cry.  Seemed  to  suffer,  but  was  observant.  On 
the  succeeding  day  opisthotonos  and  conjunctivitis  mani- 
fested themselves.     Depressed  fontanelle. 

Rve  days  later  there  was  paralysis  of  the  extremities, 
most  marked  on  right  side.  Pupils  even  and  contracted. 
Opisthotonos  gone.  Died  quietly  June  2 2d.  The  tem- 
pccunre  varied  between  98°  F.  and  101.2°  F.;  was  96.2° 
F.  on  one  occasion. 

Autopsy. — Brain  :  much  serum  and  pus  in  pia  and  be- 
neath it,  over  the  base ;  some  over  convexities.  The 
nght  parietal  lobe  contained  a  collection  of  tubercles, 
ttdi  the  size  of  a  French  pea,  with  softened  centres,  and 
nombering  about  twelve  in  all.  The  ependyma  of  the 
fateral  ventricles  contained  translucent  miliary  tubercles. 
Tl»€  kings  were  studded  with  fine  miliary  tubercles.  The 
Wneys,  spleen,  and  liver  contained  miliary  tubercles. 

Dr.  Ripley  asked  if  the  child's  lungs  were  examined 
More  death. 

Dr.  Heineman  answered  that  they  were,  and  that 
tile  (Sagnosb  of  general  tuberculosis  was  made,  from  the 
iKt  that  the  father  had  phthisis  and  the  child  gave  a  his- 


tory of  emaciation,  etc.,  which  could  not  be  accounted 
for  readily  by  the  general  physical  signs.  A  moderate 
amount  of  bronchitis  was  developed  before  death,  and  it 
was  supposed  that  there  was  pulmonary  tuberculosis. 
The  condition  of  lungs,  as  seen  in  the  specimen,  would 
not  necessarily  give  rise  to  physical  signs. 

Dr.  Ripley  was  not  prepared  to  accept  the  last  state- 
ment, as  when  there  exists  any  considerable  amount  of 
tubercular  infiltration  there  are  not  only  the  physical 
signs  of  bronchitis,  but  there  is  a  change  in  vocal  fremitus 
and  resonance  and  the  pitch  and  quality  of  the  respira- 
tory murmur. 

In  a  case  which  he  had  seen  rebently,  in  which  tubercles 
did  not  exist  except  in  the  lungs,  he  was  obliged,  in  ab- 
sence of  a  tubercular  history,  to  make  a  diagnosis  by 
means  of  physical  signs ;  there  were  a  few  bronchial 
riles,  and  decided  clumges  in  vocal  fremitus,  resonance, 
and  respiratory  murmur.  In  a  case  with  so  much  infil- 
tration as  existed  in  the  lungs  presented  by  Dr.  Heineman 
he  believed  that,  as  a  rule,  there  was  some  change  in  the 
physical  signs  mentioned  which  could  be  recognized. 

The  specimen  was,  therefore,  additionally  interesting 
on  account  of  the  absence  of  any  such  change. 

With  regard  to  the  temperature  in  tubercular  menin- 
gitis, he  made  an  autopsy  on  the  body  of  a  child  who 
died  of  that  disease,  and  during  the  last  few  days  of  life 
the  patient's  temperature  was  97^^**  F.  As  Dr.  Heine- 
man  had  said,  there  was,  very  often,  no  preagonistic  rise 
of  temperature  in  this  class  -  of  cases.  Dr.  Ripley  had 
the  records  of  between  fifty  and  sixty  cases  of  tubercular 
meningitis,  and  the  temperature  had  generally  been  low. 
The  symptoms,  he  thought,  varied  somewhat  with  the 
extent  of  invasion  of  other  organs.  Sometimes  the  tem- 
perature throughout  was  as  high  as  103°  F.,  but,  as  a  rule, 
it  was  subnormal,  or  not  higher  than  loi^  F. 

In  Dr.  Heineman's  case,  the  temperature  rose  to 
102°  F.  and  over,  and  Dr.  Ripley  thought  it  quite  prob- 
able that  the  general  tuberculosis  increased  the  rise. 

Dr.  Ferguson  asked  Dr.  Ripley  if  he  had  noticed  any 
ratio  between  the  amount  of  exudation  and  the  rise  of 
temperature  in  tubercular  meningitis. 

Dr.  Ripley  had*  not  definite  data  on  that  point,  but 
thought  that  the  temperature  was  not  especially  influenced 
by  the  quantity  of  exudation. 

The  committee  appointed  to  memorialize  the  late  Dr. 
Willard  Parker  next  offered  the  following  : 

IN   MEMORIAM — willard   PARKER,  M.D.,  LL.D. 

It  is  with  deep  and  unfeigned  regret  that  we  record  the 
death  of  our  first  acting  president,  Dr.  WiUard  Parker, 
who  expired  on  April  25,  1884,  at  the  ripe  age  of  eighty- 
four  years. 

He  was  so  well  and  capable  up  to  a  very  short  time 
ago  that  his  decease  then  would  have  been  an  unmiti- 
gated grief  to  us,  and  to  all  who  loved  him.  But  during 
the  last  eighteen  months  of  his  life  the  infirmities  of  age 
and  the  pangs  of  sickness  had  borne  so  heavily  upon 
him  that  our  sorrow  is  greatly  subdued  in  view  of  the 
peace  which  l\as  come  upon  him.  To  us  is  now  only 
left  the  gratefiil  duty  of  recording  his  manifold  virtues, 
his  great  and  honorable  services  to  his  profession  and  to 
the  public,  and  to  express  our  sincere  sympathy  to  his 
family. 

The  New  York  Pathological  Society  was  founded  in 
June,  1844,  just  forty  years  ago,  and  several  years  before 
the  London  Pathological  Society  was  established.  For  the 
first  few  months  of  its  existence  its  meetings  were  presided 
over  by  temporary  chairmen,  elected  at  each  meeting. 
Near  the  end  of  its  first  year,  viz.,  in  October,  1844,  the 
distinguished  and  lamented  Dr.  John  A.  Swett,  then  the 
leading  medical  pathologist  of  this  city,  was  elected  presi- 
dent, and  Dr.  Parker,  who  was  well  grounded  in  surgical 
pathology,  vice-president. 

Ill-health,  soon  followed  by  death,  prevented  Dr. 
Swett  from  serving,  and  we  are  not  aware  that  he  ever 
filled  the  presidential  chair.    But  so  highly  did  he  appre- 


190 


THE  MEDICAL  RECORD. 


[August  16,  1884. 


date  his  membership  in  our  Society,  that  in  his  treatise 
on  *^  Diseases  of  the  Chest/'  which  contained  a  course  of 
lectures  delivered  at  the  New  York  Hospital,  he  an- 
nounced himself  as  simply  Physician  to  the  New  York 
Hospital,  and  member  of  the  New  York  Pathological 
Society. 

Dr.  Parker,  our  first  acting  President,  was  successively 
re-elected  in  the  years  1845,  1846,  and  1847,  with  little 
or  no  opposition,  and  quickly  gave  our  Society  a  stand- 
ing before  the  medical  world  which  few  other  men  could 
then  have  given  it.  Still  he  had  good  material  to  work 
with,  for  during  these  three  years  it  counted  among  its 
members,  William  C.  Anderson,*  Daniel  Ayres,*  John  H. 
Borrowe,*  Gurdon  Buck,*  H.  D.  Bulkley,*  Alonzo  Clark, 
James  Crane,  Edward  Delafield,*  Abraham  DuBois, 
George  Elliott,*  Joh»  Forry,*  Anthony  Gescheidt,* 
Chandler  Gilman,*  Middleton  Goldsmith,  John  H.  Gris- 
com,*  Thaddeus  Halstead,*  Charles  E.  Isaacs,*  W.  W. 
Jones,  William  H.  MacNeven,*  JohnT.  Metcalfe,  George 
A.  Peters,  John  C.  Peters,  Alfred  C.  Post,  William  C. 
Roberts,*  Gustavus  A.  Sabine,  Lewis  A.  Sayre,  John  O. 
Stone,*  John  A.  Swett,*  Isaac  E.  Taylor,  Robert  Tomes, 
WilUam  H.  VanBuren,*  Hugh  Walsh,*  Robert  Watts,* 
James  R.  Wood,*  Dr.  Wotherspoon,*  and  others  of  like 
ilk. 

Of  these  thirty-seven  early  members  no  less  than  twen- 
ty-two have  died  (those  marked  thus,  *),  and  this  So- 
ciety has  repeatedly  been  compelled  to  go  in  mourning 
for  lovable  and  useful  men,  who  could  ill  be  spared. 

When  Dr.  Parker  was  called  to  the  first  presidency 
he  was  in  the  prime  of  life,  just  forty-five  years  of  age, 
having  been  born  in  1800.  He  was  a  native  of  New 
Hampshire,  and  had  only  been  six  years  in  this  city. 
But  he  was  already  Professor  of  Surgery  in  the  College 
of  Physicians  and  Surgeons,  and  was  deservedly  very 
popular,  having  risen  rapidly  to  the  position  of  one  of 
the  foremost  surgeons  and  physicians,  and  most  accept- 
able teacher  and  lecturer,  not  only  in  the  eyes  of  New 
York,  but  of  the  whole  country. 

He  had  been  a  pupil  and  assistant  of  Dr.  John  C. 
Warren  in  anatomy  and  surgery,  had  served  in  several 
hospitals,  and  been  a  teacher  and  professor  of  anatomy 
and  surgery  in  other  colleges. 

He  was  an  excellent  presiding  officer,  and  took  a  warm, 
well'Sustained  interest  in  the  welfare  of  this  Society. 
Among  his  earliest  services  to  it  was  the  active  part  he 
took,  with  others,  in  1845,  in  housing  it  in  the  College 
of  Physicians  and  Surgeons,  where  it  has  remained  until 
this  day,  and,  hopefully,  always  will  remain,  to  the  honor 
and  credit  of  both. 

It  was  no  small  benefit  to  the  infant  society  to  be 
settled  so  conveniently  for  its  peculiar  work,  and  at  such 
a  small  annual  expense.  This  has  enabled  it  to  preserve 
all  its  records  and  minutes  for  forty  years  ;  to  have  them 
widely  published  in  various  journals,  and  to  issue  several 
v(^umes  of  its  transactions  free  to  its  members. 

Dr.  Parker  was  always  a  thoughtful  pathologist,  rather 
than  a  minute  pathological  anatomist ;  just  as  he  was  a 
great  conservative  surgeon  and  hygienist,  rather  than  a 
mere  operator.  Although  he  had  a  wonderful  knowledge 
of  anatomy  and  of  the  principles  of  surgery,  the  glamour 
of  even  major  operations  never  seemed  to  have  the 
slightest  charm  for  him.  He  always  appeared  to  think 
most  surgical  operations  were  unfortunately  rendered 
necessary  by  the  imperfections  of  medical  and  hygienic 
art,  greatly  aided  by  the  ignorance  and  obstinacy  of 
patients.  He  obviously  regarded  great  pathological 
specimens  as  so  many  failures  in  the  treatment  of  dis- 
ease. He  was  always  rational,  rather  than  merely  em- 
pirical, or  mechanical,  and  ever  aimed  to  prevent  disease 
and  avoid  operations,  rather  than  to  drug  his  patients, 
mutilate  them,  or  make  post-mortem  examinations  of  them. 

Still  he  rejected  no  aids  in  the  study  of  disease,  and 
always  maintained  his  active  connection  ¥dth  this  Society, 
even  when  loaded  with  numberless  other  cares  and  bur- 
densome honors,  and  while  laboring  so  hard,  from  1866 


down,  in  the  establishment  and  working  of  the  Metro- 
politan Board  of  Health,  where  his  views  on  hygiene 
could  have  full  play.  He  was  ever  ready  to  sustain  us 
with  his  presence  and  example,  and  with  a  strong  hand, 
kindly  heart,  active  brain,  and  ready  purse.  Even  in  the 
last  year  of  his  life,  when  almost  crushed  with  the  in- 
firmities of  his  great  age  and  the  pangs  of  disease,  he 
delighted  to  counsel  for  its  welfare  and  honor,  and  to  re- 
view its  early  history  and  struggles. 

For  these  and  many  other  things  this  Society  owes 
a  debt  of  gratitude  to  the  memory  of  Dr.  Parker,  which 
it  is  not  only  eminently  becoming  for  it  to  acknowledge, 
but  which  we  are  only  too  happy  to  promptly  and  frankly 
render. 

To  those  who  knew  him  in  his  prime  we  need  not  say 
that  we  were  very  proud  of  our  first  president  as  a  peat 
and  good  man,  a  faithful  citizen,  an  eminent  physician 
and  surgeon,  a  brilliant  teacher,  and  a  careful  watchman 
over  the  public  health. 

Many  of  us  went  further,  and  took  a  justifiable  pride 
in  those  winning  personal  and  mental  endowments  which 
a  kind  Providence  had  showered  upon  him ;  in  his  manly 
beauty  and  impressive  stature,  in  his  attractive,  gentle- 
manly appearance  and  kindly  presence,  in  his  great 
mental  vigor  and  physical  activity,  in  his  exceptionally 
regular  and  correct  personal  habits,  in  his  buoyant  and 
even  joyish  temperament,  in  his  spotless  morality  and 
deep  religious  convictions,  we  thought  him  an  embodi- 
ment in  himself  of  almost  all  that  is  good,  useful,  lova- 
ble, and  we  are,  and  all  his  friends  should  be,  greatly 
comforted  in  his  loss  that  these  high  qualities  were  at 
our,  and  their,  service  so  long,  and  so  far  beyond  the 
period  of  life  ordinarily  allotted  to  man,  for  work  and 
for  the  comfort  of  his  fellows. 

He  has  gone  to  join  that  not  small  band  of  our  illus- 
trious deceased  presidents,  himself  by  far  not  the  least, 
quorum  pars  magna  fuiU  His  closes,  for  a  time,  the  list 
which  contains  the  honored  names  of  Wm.  H.  Van 
Buren,  Robert  Watts,  Edmund  R.  Peaslee,  Gurdon 
Buck,  Ernst  Kracowizer,  James  R.  Wood,  John  A* 
Swett,  Erskine  Mason,  Charles  E.  Isaacs,  Jackson  Bol- 
ton, David  S.  Conant,  Wm.  B.  Bibbins,  and  Henry  Van 
Arsdale. 

Dr.  John  A.  Swett,  our  first  nominal  president,  died 
at  the  early  age  of  forty-five  years.  Dr.  James  R.  Wood, 
our  second  president,  was  born  in  18 16,  and  died  aged 
sixty-five  years.  Dr.  Wm.  H.  Van  Bureu,  our  fourth 
president,  was  bom  in  1819,  and  died  aged  sixty-five 
years.  Dr.  Charles  K  Isaacs,  our  fifth  president,  was 
born  in  1822,  and  died  aged  forty-eight  years.  Dr.  Jack- 
son Bolton,  our  eighth  president,  was  bom  in  18 15,  and 
died  aged  fifty-one  years.  Dr.  Robert  Watts,  our  ninth 
president,  died  aged  fifty-five  years.  Dr.  Edmund  R, 
Peaslee,  our  tenth  president,  was  bom  in  18149  and  died 
aged  sixty-five  years.  Dr.  David  S.  Conant,  our  four- 
teenth president,  died  aged  forty-five  years.  Dr.  Gurdon 
Buck,  our  sixteenth  president,  was  bom  in  1807,  and 
died  aged  seventy.  Dr.  Wm.  B.  Bibbins,  our  eighteenth 
president,  was  bom  in  1825,  and  died  aged  forty-six 
years.  Dr.  Emst  Kracowizer,  our  twentieth  president, 
was  born  in  1822,  and  died  aged  fifty-three  years.  Dr. 
Erskine  Mason,  our  twenty-fourth  president,  died  aged 
forty  years.  Lastly,  Dr.  Willard  Parker,  our  first  presi- 
dent, was  born  in  1800,  and  died  aged  eighty-four  years. 

Thus  it  will  be  seen  that,  with  the  sole  exception  of 
Dr.  Parker,  none  of  our  deceased  presidents  lived  to  be 
very  old  men.  Only  one  beside  him.  Dr.  Gurdon  Buck, 
reached  his  seventieth  year.  No  less  than  three---viz., 
Drs.  Van  Buren,  Peaslee,  and  James  R.  Wood — died  in 
their  sixty-fifth  year.  Drs.  Bolton,  Kracowizer,  and 
Watts  died  respectively  in  their  fifty-first,  fifty-third,  and 
fifty-fifth  years.  No  less  than  six  died  before  they 
attained  their  fiftieth  year — viz.,  Dr.  Isaacs,  at  forty- 
eight  ;  Dr.  Bibbins,  at  forty-six ;  Drs.  Swett  and  Conant, 
at  forty-five  ;  and  the  beloved  Dr.  Mason  at  the  very 
early  age  of  forty  years. 


^^ugust  16,  1884.] 


THE  MEDICAL  RECORD. 


191 


Many  of  our  deceased  presidents  were  always  delicate  j 
and  many  were  cut  off  by  sudden  and  sharp  sick- 
ness. Dr.  Parker  c^me  from  a  long-lived  and  excellent 
pre-Revolutionary  stock  on  both  sides  of  his  family.  He 
lived  upon  a  farm  until  he  was  nineteen  years  old,  and 
although  he  worked  hard  and  performed  excellent  service 
for  the  rest  of  his  life,  he  always  took  great  care  of  his 
general  health. 

Our  senior  living  ex-president,  in  point  of  years,  is 
Dr.  Alfred  C.  Post,  thirteenth  president,  born  in  1806, 
aged  seventy-eight     Our  senior  ex-president,  in  point  of 
service,  is  Dr.  Thomas  M.  Markoe,  fourth  president,  born 
in  182 1,  aged  sixty-three  years.     Then  follow  Dr.  John 
T.  Metcalfe,  seventh  president,  aged  sixty-two  ;  Dr.  John 
C.  Dalton,  twelfth  president,  born  1825,  is  aged  fifty-nine ; 
Dr.  Thos.  C.  Finnell,  fourteenth  president,  born  1827^  is 
aged  fifty-seven ;  Dr.  Abraham  Jacobi,  sixteenth  presi- 
dent, bom  1830,  is  aged  fifty-four ;  Dr.  Henry  B.  Sands, 
seventeenth  president,  born  1830,  is  aged  fifty-four ;  Dr. 
Lewis  A.  Sayre,  twenty-first  president,  born  in  1820,  is 
aged  sixty-four  years ;  Dr.  Joseph  C.  Hutchison,  twenty- 
second  president,  born  in  1827,  is  aged  fifty- seven;  Dr. 
Alfred  L.  Loomis,  twenty-third  president,  bom  in  1831, 
is  aged  fifty-three  years ;  Dr.  Herman  Knapp,  twenty-fifth 
preadent,  is  aged  fifty-two  years ;  Dr.  Francis  Delafield, 
twenty-sixth  president,  born  in  1841,  is  aged  forty-three 
years;  Dr.  Charles  K.  Briddon,  twenty-seventh  presi- 
dent, bora  in  1827,  is  aged  fifty-seven;  Dr.  Edward  G. 
Jancway,  twenty-eighth  president,  born  in  1841,. is  aged 
forty-three  years;  Dr.  John  C.  Peters,  born  in  1819,  twen- 
ty-ninth president,  is  aged  sixty-five  years ;  Dr.  Edward  L. 
Keyes,  thirtieth  president,  bom  in  1843,  is  aged  forty-one 
jrears;  Dr.  T.  E.  Sattcrthwaite,  thirty-first  president,  born 
in  1843,  is  aged  forty-one  years  ;  Dr.  Ed.  C.  Seguin,  thirty- 
second  president,  bom  in  1843,  is  aged  forty-one  years ;  Dr. 
George  F.  Shrady,  bora  in  1837,  is  aged  forty-seven  years. 
It  will  be  seen  that  the  majority  of  our  presidents  have 
been  young  men.     Dr.  Swett  was  under  forty  years  of 
age  when  elected  president ;  Dr.  Parker,  forty-five ;  .Dr. 
James  R.  Wood,  thirty-two ;  Dr.  Markoe,  only  thirty ; 
Dr.VanBuren,  thirty-one  ;  Dr.  Isaacs,  only  twenty-nine  ; 
Dr.  Metcalfe,  thirty-one ;  Dr.  Van  Arsdale,  thirty-seven  ; 
Dr.  Bolton,  thirty-nine ;  Dr.  Watts,  forty-nine  ;  Dr.  Peas- 
Ice,  foity-four ;  Dr.  Dalton,  thirty-four;  Dr.  Post, fifty-five; 
Dr.  Finnell,  thirty-five ;  Dr.  Conant,  forty  ;  Dr.  Jacobi, 
ihirty-four ;  Dr.  Buck,  fifty-eight ;  Dr.  Sands,  thirty-six  ; 
Dr.  Bibbins,  forty-two ;  Dr.  Kracowizer,  forty-six ;  Dr. 
Sayre,  forty-nine  ;  Dr.  Hutchison,  forty-three  ;  Dr.  Loo- 
mis, forty;  Dr.  Mason,  thirty-eight;  Dr.  Knapp,  forty- 
two  ;  Dr.  Delafield,  thirty-four ;  Dr.  Briddon,  forty-nine  ; 
Dr.  Jancway,  thirty-six ;  Dr.  Peters,  fifty-nine ;  Dr.  Keyes, 
thirty-six;  Dr.  Satterthwaite,  thirty-seven;  Dr.  Seguin, 
thirty-niDc  ;  Dr.  Shrady,  forty-six  years. 

Signed  by  authority,  John  C.  Peters,  Chairman, 

Geo.  L.  Peabody. 


Lactic  Acid  occurs  in  sour  milk  from  the  spontaneous 
fermentation  of  sugar  of  milk  under  the  influence  of 
casein ;  this  transformation  is  called  lactic  fermentaiion. 
A  similar  change  is  produced  in  dextrine,  glucose,  cane- 
SQgar,  etc.,  by  the  action  of  casein  and  other  protein 
compounds.'  It  is  found  in  many  vegetable  products 
vbidi  have  turned  sour.  The  sarcolactic  acid  of  flesh 
ud  muscle  is  very  sour,  and  in  excess  causes  rheuma- 
^  It  is  soluble  in  ether,  alcohol,  and  water,  coagulates 
mlk  and  albumen,  displaces  carbonic  and  acetic  acids, 
and  yields  salts  soluble  in  water  and  alcohol.  It  has  been 
«ed  in  dyspepsia  in  place  of  hydrochloric  acid ;  and  when 
ffvcn  in  diabetes  symptoms  of  acute  rheumatism  have 
appeared  which  have  subsided  on  stopping  the  acid.  In« 
^unmation  of  the  joints  and  pericardium  have  been 
^ansed  by  it  in  animals.  It  is  useful  in  all  alkaline  dis- 
cues,  including  typhus  and  typhoid  fevers,  erysipelas, 
^thcria,  etc 


THE  BERLIN  SOCIETY  OF  INTERNAL  MEDI- 
CINE. 

Stated  Meetings  June  30,  1884. 

Herr  Leyden,  President,  in  the  Chair. 

(Special  Report  to  Ths  Mbdical  Rkcord.) 

The  Society  having  been  called  to  order,  the  first 
speaker  of  the  evening  was  Herr  Mendelsohn,  who 
presented  some  preparations  showing 

tubercle  bacilli  in  the  urine  and  kidneys. 

The  patient  had  suffered  for  some  time  from  a  bladder 
trouble  and  incontinence  of  urine,  and  died  rather  sud- 
denly from  meningitis.  The  urine  was  cloudy,  alkaline 
in  reaction,  and  contained  albumen.  The  urine  having 
been  evaporated  and  the  driecl  sediment  stained,  the 
tubercle  bacilli  were  seen  to  be  present  in  large  numbers. 
Koch,  in  his  latest  work  on  the  etiology  of  phthisis,  has 
described  the  bacilli  obtained  by  culture  as  large  bodies 
twisted  into  multiple  serpentine  shapes,  the  smallest  of 
them  looking  like  the  letter  S.  The  bacilli  found  in  the 
urine,  and  also  in  pus  taken  from  the  kidney  post  mor- 
tem, presented  exactly  this  appearance. 

Herr  A.  Baginsky  then  exhibited  some  specimens 
demonstrating  the 

changes  induced  in  the  intestinal  canal  of  chil- 
dren BY  chronic  catarrh. 

He  had  not  seen  any  mention  made  of  this  condition 
in  any  of  the  recent  text-books.  The  affection  attacks 
first  the  mucous  coat,  but  passing  gradually  into  the 
deeper  layers  induces  there  changes  of  a  very  serious 
character.  A  child,  seven  months  old,  was  brought  to 
him  for  treatment,  suffering  for  some  time  from  diarrhoea 
and  great  emaciation.  The  stools  were  thin,  mucous, 
and  of  a  greenish  color.  After  a  period  of  temporary 
improvement  the  diarrhoea  returned,  and  soon  the  child 
died.  At  the  autopsy  the  mucous  membrane  of  the 
large  intestine  was  seen  to  be  swollen  and  thickly  studded 
with  granulations,  so  that  the  intestine,  when  smoothed 
out,  looked  like  a  coarse  file.  On  microscopical  exami- 
nation the  glands  of  Lieberkiihn  were  found  to  have 
undergone  peculiar  changes.  They  were  of  all  sorts  of 
odd  shapes,  presenting  warty  outgrowths  and  bifurcations, 
and  on  careful  section  the  epithelium  was  seen  to  be  the 
seat  of  hyaline  degeneration.  The  speaker  expressed  the 
opinion  that  Lieberkiihn' s  glands  possessed  a  certain 
digestive  function,  and  that  the  patholoncal  changes  oc- 
curring in  them  should  be  more  caremlly  studied  than 
they  have  hitherto  been. 

Herr  Boecker  then  related  a  case  of 

gangrenous  inflammation  of  the  larynx, 

situated  in  the  aryteno-epiglottidean  fold.  Laryngeal 
examination  showed  large  shreds  of  gangrenous  tissue 
hanging  down  from  the  neighborhood  of  the  pyramidal 
sinus.  The  patient  stated  that  he  had  been  suddenly 
seized,  ten  weeks  before,  with  sore  throat  apd  difficulty 
in  deglutition.  At  the  same  time  there  was  considerable 
dyspnoea,  and  when  this  subsided  the  breath  became  so 
extremely  offensive  that  he  could  not  eat. 

Herr  Altmann  then  read  an  interesting  paper  on 
some  of  the 

SUCCEDANEA   OF  DIGITALIS. 

He  had  made  a  number  of  trials  during  the  past  year 
with  caffeine  and  adonis  vemalis  in  the  treatment  of 
cardiac  and  renal  diseases,  and  thought  that  a  recital  of 
the  results  obtained  by  him  would  not  be  without  in- 
terest.    His  experience  with 

CAFFEINE 

had  been  that  under  its  influence  the  heart's  action  was 
strengthened  and  the  arterial  tension  increased.     Its   in- 


192 


THE  MEDICAL  RECORD. 


[August  1 6,  i884« 


fluence  in  reducing  the  frequency  of  the  pulse  was  not  as 
marked  as  that  of  digitalis.  The  urine  was  invariably 
increased  in  quantity  during  the  administration  of  the 
drug.  It  had  been  stated  by  Riegel  that  the  simultane- 
ous exhibition  of  narcotics  weakened  the  action  of  caf- 
feine, and  the  author's  experience  had  led  him  to  the 
same  conclusion. 

ADONIS  VERNALIS, 

a  wild  plant  of  the  order  of  ranunculaceas,  growing  in 
southern  Europe,  was  at  one  time  employed  as  a  drastic 
cathartic,  and  also  as  a  heart-tonic,  but  had  soon  been 
forgotten.  Some  trials  had  of  late  been  made  of  it  by 
Dr.  Bubnoff,  at  the  instance  of  Professor  Botkin,  when 
it  was  found  to  possess  some  really  valuable  properties 
as  a  heart-tonic  and  diuretic.  Cervello  had  found  the 
active  principle  of  the  plant  to  reside  in  a  glucoside  to 
which  he  gave  the  name  of 

ADONIDINK. 

Its  action  was  very  similar  to  that  of  di^italine  in 
strengthening  the  cardiac  pulsations,  increasing  arterial 
tension,  and,  after  its  continued  administration  for  a 
length  of  time,  increasing  also  the  irritability  of  the 
striped  muscular  tissue. 

The  author  had  employed  adonis  in  a  number  of  cases 
of  valvular  disease,  fatty  degeneration,  and  myocarditis, 
as  well  as  of  parenchymatous  nephritis.  He  gave  in  de- 
tail the  history  of  two  cases  in  which  he  had  employed 
adonis  with  signal  success  after  having  been  obliged  to 
discontinue  digitalis  on  account  of  the  dangerous  symp- 
toms produced  Yet  adonis  did  not  act  equally  well  in 
all  cases.  In  two  instances  he  was  forced  to  give  it  up 
owing  to  its  causing  pain  in  the  kidneys  and  general 
malaise.  The  simultaneous  administration  of  narcotics 
in  these  cases  had  seemed  to  influence  its  action  in  no 
noticeable  degree.  All  observers  agreed  that  there  was 
no  cumulative  action  of  the  drug.  That  large  doses 
might  be  given  without  danger  was  evidenced  by  the  fact 
that  the  Russians  were  accustomed  to  take  it  in  unlim- 
ited quantities  as  a  remedy  against  the  drinking  habit. 
It  was  given  medicinally  in  infusion  or  decoction 
(3  j.-ij.  to  5  vj.),  in  doses  of  a  tablespoonful  four  or  more 
times  a  day.  In  conclusion,  Herr  Altmann  submitted 
that  adonis  vemalis  is  a  cardiac  regulator  in  the  same 
sense  as  is  digitalis.  It  strengthens  the  heart's  action 
and  reduces  the  number  of  its  pulsations,  raising  at  the 
same  time  arterial  tension,  and  increasing  markedly 
diuresis.  The  indications  for  the  use  of  adonis  are  the 
same  as  for  digitalis,  but  it  is  more  rapid  in  its  action 
than  the  latter  drug,  and  never  exhibits  any  cumulative 
effect  Finally,  it  may  often  be  productive  of  good  re- 
sults where  digitalis  has  failed. 

Herr  Michaelis  had  had  a  case  of  excessive  ascites 
and  oedema  which  had  resisted  all  the  ordinary  diuretics, 
and  in  which  digitalis  gave  rise  to  most  alarming  symp- 
toms. As  a  last  resort  he  determined  to  try  adonis,  and 
was  delighted  to  find  that  under  its  influence  the  excre- 
tion of  urine  was  at  once  increased.  The  ascites  and 
knasarca  disappeared  within  a  short  time. 

Herr  W.  Lublinski  was  induced  to  try  adonis  ver- 
nalis  on  the  recommendation  of  Professor  Botkin,  of  St. 
Petersburg.  He  had  used  it  in  a  number  of  cases  of 
dropsy  consequent  upon  valvular  insufficiency,  cardiac 
debility,  and  Bright's  disease.  The  principal  effect  of 
the  drug,  and  that  by  which  it  won  its  fame  in  Russia,  is 
seen  in  increased  diuresis.  He  had  observed  one  pecu- 
liarity in  the  diuresis  of  adonis,  which  was  that  the  spe- 
cific gravity  remained  high,  although  the  total  amount  of 
urine  excreted  was  so  greatly  increased.  This  was  due 
to  the  fact,  noticed  by  Botkin,  that  there  was  an  in- 
creased excretion  of  urates  and  chlorides  during  the  ad- 
ministration of  the  drug.  The  speaker  had  not  observed 
the  favorable  influence  upon  the  heart  which  others  had 
claimed  for  adonis.  In  a  few  instances  only  had  he  seen 
any  increase  of  strength  in  the  heart's  action,  neither 
had  the  pulse  become  less  rapid  and  more  regular,  nor 


the  dyspnoea  less  urgent.  In  most  cases  he  was  obliged 
to  fall  back  on  digitalis  in  order  to  obtain  this  result. 

In  addition  to  Uiis  disadvantage,  adonis  possesses  some 
very  unpleasant,  though  not  dangerous,  properties. 
Herr  Lublinski's  patients  had  complained  much  of  the 
extreme  bitterness  of  the  drug,  and  he  had  found  nothing 
which  would  in  any  noticeable  degree  disguise  this  taste. 
It  often  caused  nausea,  and  even  vomiting,  and  some- 
times had  to  be  discontinued  on  account  of  a  diarrhoea 
which  was  excited  by  it  In  summing  up  the  results  of 
his  experience,  the  speaker  maintained  that  adonis  ver- 
nalis  could  never  be  accepted  as  a  substitute  for  digitalis  in 
all  cases.  It  is  useful  in  those  cases  in  which  it  is  desir- 
able to  induce  diuresis ;  but  even  here  it  should  be  given 
only  when  digitalis  is  contraindicated  by  the  existence 
of  a  very  slow  pulse,  or  when  a  cumulative  action  is  to 
be  feared.  He  stated,  for  the  benefit  of  those  who  might 
wish  to  try  it  in  their  practice,  that  it  could  be  obtained 
of  Gehe  &  Co.,  in  Dresden. 

The  active  principle,  adonidine,  is  a  glucoside,  con. 
tainin^  no  toxic  proi)erties.  It  is  amorphous,  dissolving 
freely  u  alcohol,  but  only  slightly  soluble  in  water  and 
ether.  The  maximum  dose  for  a  frog  is  i^  grain.  It 
has  no  cumulative  action. 

Herr  Lenhartz  had  used  adonis  in  a  number  of  cases 
of  pleurisy,  nephritis,  weak  heart,  etc.,  in  which  all  other 
remedies  had  failed.  The  results  were  in  general  very 
fisivorable.  He  was  especially  pleased  with  the  diuretic 
action  of  the  drug. 

Herr  Leyden  stated  that  he  was  engaged  in  the  at- 
tempt ,to  make  other  more  satisfactory  preparations  of 
adonis  than  those  hitherto  in  use,  but  his  labors  had  as 
yet  been  unproductive  of  result  The  active  principle 
was  unsuited  for  internal  administration,  owing  to  its 
slight  degree  of  solubility  in  water.  Adonis  had  advan- 
tages as  well  as  disadvantages  in  comparison  with  digi- 
talis. It  exerts  no  regulating  action  upon  the  heart,  and 
seldom  slows  the  pulse  to  any  appreciable  degree.  Its 
chi^  advantage  is  that  it  has  no  cunaulative  effect,  and 
further,  it  causes  no  such  digestive  disturbances  as  are 
frequently  seen  to  follow  the  prolonged  administration  of 
digitalis.  It  can  also  be  given  in  many  cases  of  weakened 
heart  and  slow  pulse  in  which  digitalis  would  be  contra- 
indicated.  It  is,  upon  the  whole,  the  best  succedancum 
of  digitalis  that  we  possess. 

As  regards 

convallaria, 

the  speaker  said  that  his  early  experience  with  the  drug 
had  not  been  of  such  a  nature  as  to  encourage  him  to 
continue  in  its  use.  Squills  resembled  adonis  in  its  diu- 
retic action,  but  it  was  less  reliable.  He  thought  the 
history  of  adonis  exemplified  very  strikingly 

THE   relations    BETWEEN    PHYSIOLOGICAL    EXPERIMENT 
AND  MEDICAL  PRACTICE. 

There  are  many  substances  which  possess  properties 
similar  to  those  of  digitalis,  and  which  give  almost  iden- 
tical results  in  experiments  upon  frogs.  But  in  practice 
it  is  found  that  the  various  drugs  are  by  no  means  of  equal 
value.  Thus  it  is  evident  that  in  the  treatment  of  patho- 
logical conditions  we  cannot  rely  wholly  upon  the  prop- 
erties of  any  drug  as  determined  in  the  laboratory,  but 
must  determine  anew  for  ourselves,  by  actual  experi- 
ment, what  value  each  substance  possesses  when  brought 
face  to  face  with  disease. 

The  Society,  on  motion,  then  adjourned. 


The  Forceps  in  Breech  Presentations. — Profes- 
sor R.  Harvey,  of  Calcutta',  advocates  the  use  of  the 
forceps  in  breech  presentations  in  certain  cases  {Indian 
Medical  Gazette^  June,  1884).  In  this  opinion  he  is  now 
supported  by  Huter,  Haake,  Lusk,  Gooch,  Hamilton, 
Miles,  and  Agnew,  so  that  the  older  views  as  to  the 
inutility  of  this  procedure  need  to  be  somewhat  changed. 


August  1 6.  1884,] 


THE  MEDICAL  RECORD. 


193 


THE  BIOLOGICAL  SOCIETY  OF  PARIS. 

Slated  Meetings  July  12,  1884. 
M.  Paul  Bert,  President,  in  the  Chair. 

(Special  Report  for  Thb  Mbdical  Record.) 

The  Society  was  called  to  order  by  the  President. 

M.  Mairet  detailed  the  results  of  some  experiments 
made  by  him  to  determine  the  modifications  occurring  in 
the 

elimination  of  phosphoric  acid 

in  the  subjects  of  epilepsy,  melancholia  or  mania  In  the 
latter  disease  the  results  differ  according  to  the  particular 
phase  during  which  the  investigations  are  made.  In  the 
stage  of  excitement  there  is  an  increase  in  the  elimination 
of  nitrogen  and  phosphoric  acid.  In  the  period  of  de- 
pression the  nitrogen  and  alkaline  phosphates  are  dimin- 
ished, white  the  earthy  phosphates  are  increased.  There 
is  a  decrease  in  both  nitrogen  and  phosphates  during  a 
remission.  In  epilepsy  there  is  an  increased  elimination 
of  these  substances  during  an  attack.  In  melancholia  the 
earthy  phosphates  are  increased  in  amount,  and  the 
alkalme  phosphates  and  nitrogen  are  diminished.  M» 
Mairet  thought  his  investigations  were  of  practical  value 
as  furnishing  indications  for  the  treatment  of  these  affec- 
tions. 

M.  Henninger  described  the  method  employed  by 
him  in  determining  the 

PROPORTION   OF   NITROGEN   IN   UREA. 

This  method  was  a  modification  of  that  proposed  by  Dr. 
Kjedal,  of  Copenhagen.  It  was  very  simple,  and  could 
be  completed  within  two  hours. 

M.  Grbhant  then  called  attention  to  the  dangers  of 
the 

DISINFECTION  OF   BAGGAGE  BY   NITROUS  VAPORS, 

as  was  done  in  some  of  the  railway  stations.  The  porters 
who  removed  the  disinfected  baggage  incurred  no  slight 
risk.  Experiments  upon  dogs  had  shown  that  the  res- 
piration of  nitrous  vapors  was  always  dangerous,  and 
m%ht  even  be  fatal  in  its  consequences.  It  was  very 
well  to  try  to  kill  the  microbes,  but  it  was  hardly  the  cor- 
rect thing  to  kill  men  at  the  same  time. 

M.  Rabuteau  thought  that  the  question  raised  by  M. 
Grdhant  was  one  of  very  grave  importance.  The  inhala- 
tion of  nitrous  vapor  determines  profound  changes  in  the 
blood,  the  effects  of  which  may  not  be  seen  immediately. 
Workmen  exposed  to  these  fumes  had  been  known  to  die 
suddenly  after  they  had  returned  to  their  homes,  although 
vhile  at  work  they  had  experienced  no  ill  effects. 

M.  Henninger  cited  the  case  of  a  chemist  in  Edin- 
burgh, who  died  in  consequence  of  inhaling  these  vapors. 
His  laboratory  assistant  was  also  made  very  ill,  but  finally 
recovered. 

M.  Grkhant  read  a  note  upon 

ALIMEITFATION    BY   PEPTONES, 

and  demonstrated  a  simple  method  of  making  peptones 
for  therapeutic  use. 

M.  BouCHERBAU  had  prescribed  peptones  in  a  number 
of  cases  of  mental  disease,  and  had  observed  a  marked  im- 
provement in  the  physical  condition,  and  sometimes  also 
in  the  mental  state. 

M.  Henninger  mentioned  a  paper  which  he  had 
published  upon  the 

rectal  administraiion  of  peptones. 

He  also  related  an  instance  in  which  a  patient,  who  had 
become  greatly  reduced,  lived  for  several  weeks  upon  in- 
jections of  peptones.  He  always  added  sugar  and 
laudanum  to  the  enemata.  He  had  never  seen  any  in- 
flammation of  the  rectum  following  these  injections. 

M.  Quinquand  had  studied  the  effects  of  peptones  in 
the  direction  of  increased  bodily  weight  and  augmentation 
in  the  quantity  of  urea  excreted.  He  had  tound  an  in- 
aeased  formation  of  urea  to  take  place  at  the  same  time 


that  the  patient  gained  in  weight  This  he  thought, 
proved  conclusively  that  the  peptones  were  assimilated^ 
He  related  several  cases  in  which  he  had  observed  bene- 
fit from  this  mode  of  alimentation. 

M.  Dastre  thought  that  the  facts  related  by  M.  Quin- 
quand were  especially  valuable  in  disproving  the  state- 
ments made  by  certain  German  writers.  These  latter, 
having  examined  only  the  products  of  respiration,  pre- 
sumed to  assort  that  peptones  were  inert. 

The  Society  then  adjourned. 


THE  HOSPITALS    MEDICAL  SOCIETY  OF 
PARIS. 

Stilled  Meetings  July  11,  1884. 
M.  BucQUOY,  President,  in  the  Chair. 

(Special  Report  for  Thb  Medical  Rboord.) 

The  Society  having  been  called  to  order,  M.  Besnisr 
delivered  an  address  of  some  length  upon  the  desirability 
of  preparing  for 

THE   APPROACHING   CHOLERA  EPIDEMIC. 

He  thought  it  necessary  for  the  physicians  of  Paris  to 
bestir  themselves  if  they  wished  to  avoid  a  repetition  of 
what  had  just  occurred  at  Marseilles.  The  daily  papers 
were  full  of  the  visit  made  by  Dr.  Koch,  in  the  character 
apparently  of  sanitary  inspector  and  adviser  to  the  phy- 
sicians and  municipality  of  that  city.  Now,  either  the 
physicians  knew  beforehand  all  that  Dr.  Koch  told  them, 
and  his  advice  was  therefore  superfluous,  or  else  they  did 
not  know  it,  and  then  it  was  not  to  Dr.  Koch  that  they 
should  have  applied  for  instruction.  M.  Besnier  then 
spoke  of  the  measures  that  had  been  taken  in  Paris  to 
prepare  for  the  probable  appearance  of  the  disease. 
Two  hospitals,  of  the  opacity  of  two  hundred  beds  each, 
had  been  made  ready,  one  on  each  bank  of  the  Seine. 
In  the  event  of  an  epidemic,  therefore,  there  was  ac» 
commodation  for  four  hundred  patients  at  once,  and  then 
there  would  be  time  enough  to  prepare  for  niore  if  occa- 
sion arose.  He  stated,  in  answer  to  a  question  of  one 
of  the  members,  that  experiments  were  now  being  con- 
ducted to  determine  the  practicability  of 

BURNING  THE   CHOLERAIC  DISCHARGES. 

This  was  to  be  done  by  means  of  portable  furnaces 
mounted  on  wheels.  The  dejections  could  be  thrown 
into  the  furnaces  as  soon  as  they  were  received.  If  this 
idea  were  practicable,  it  would  certainly  be  an  efficient 
way  of  destroying  every  contagious  principle. 
M.  Vallin  then  read  a  very  interesting  paper  upon  the 

TRANSMISSIBILITV  OF  PULMONARY  PHTHISIS. 

The  paper  was  in  reality  the  report  of  the  committee  on 
phthisiology  appointed  by  the  Society  some  time  pre- 
viously. The  author  first  gave  the  facts  upon  which  was 
based  the  doctrine  of  the  inoculability  of  tuberculosis, 
and  stated  that  the  contagious  principle  was  contained 
in  the  tubercular  matter,  the  muscles,  and  perhaps  also 
in*  the  lymph  and  the  milk.  It  had  been  admitted  that 
the  tubercular  virus  was  inoculable,  but  at  the  same  time 
it  had  been  denied  by  some  that  it  could  be  transported 
from  one  person  to  another  in  the  ordinary  conditions  of 
every-<lay  life.  The  author  thought,  however,  that  the 
evidence  of  the  contagiousness  of  phthisis  was  certainly 
as  convincing  as  that  in  the  case  of  glanders,  and  there 
were  very  few  who  would  care  to  deny  the  contagious- 
ness of  the  latter  disease  One  fact  worthy  of  careful 
study  in  this  connection  was  the  danger  of  the  formation 
of 

CENTRES   OF  CONTAGION 

in  houses  in  which  a  number  of  phthisical  patients  had 
been  collected  together.  Cohnheim,  who  had  formerly 
denied  the  contagious  nature  of  tuberculosis,  was  con- 
verted to  the  opposite  opinion  by  the  fact  that  his  ani- 
mals all  became  tuberculous,  although  they  had  not  been 


194 


THE  MEDICAL  RECORD. 


[August  i6,  1884. 


inoculated,  simply  from  living  in  his  laboratory,  which 
had  become  infected  with  the  tubercular  virus. 

It  has  been  denied  that  the  facts  observed  in  animals 
were  applicable  to  man,  but  the  cases  of  contagion  re- 
corded by  the  Collective  Investigation  Committee  in 
England  are  so  numerous  as  to  be  virtually  conclusive. 
Of  the  1,078  answers  received  to  their  circular  con- 
cerning the  transmission  of  tuberculosis,  261  were 
affirmative.  Of  this  number  there  were  190  cases  in 
which  phthisis  occurred  in  those  who  had  no  hereditary 
predisposition.  A  similar  result  was  obtained  by  the 
German  committee.  One  case  in  this  category  was 
particularly  striking.  Dr.  Hyades,  a  physician  attached 
to  the  Cape  Horn  mission,  stated  that  phthisis  was  un- 
known among  the  natives  of  Terra  del  Fuego  before  the 
advent  of  the  English  missionaries,  and  this  despite 
the  fact  that  they  lived  in  the  open  air,  but  scantily 
clothed  and  exposed  to  all  the  vicissitudes  of  an  intem- 
perate climate.  But  after  they  had  been  partially  civil- 
ized, although  they  were  now  warmly  clad  and  lived  in 
decent  houses,  they  were  nearly  decimated  by  phthisis. 
Among  the  missionaries  with  whom  they  lived  there  were 
several  with  tuberculosis. 

It  had  been  asserted  that  those  who  became  tuber- 
culous after  nursing  phthisical  patients,  became  so  in 
consequence  of  the  fatigue  and  anxiety  from  which  they 
suffered.  But  if  this  were  the  case,  those  who  nurse  pa- 
tients with  cardiac,  renal,  or  other  chronic  diseases  ought 
equally  to  become  consumptive,  and  this,  experience 
shows,  does  not  occur.  It  is  true  the  negative  testimony 
against  the  contagiousness  of  tuberculosis  is  very  strong, 
but  taken  in  connection  with  the  positive  testimony  on 
the  other  side,  it  only  proves  that  pulmonary  consump- 
tion is  not  as  markedly  contagious  as  some  other  diseases, 
measles  or  small-pox  for  example. 

Having  thus  established,  M.  Vallin  continued,  the  con- 
tagious nature  of  the  disease,  he  would  now  lay  down 
some  general  rules  bearing  upon  the 

PROPHYLAXIS  OF  TUBERCULOSIS. 

Physicians  should  be  careful,  while  seeking  to  enforce 
the  necessary  prophylactic  measures,  not  to  preach  too 
strongly  the  theory  of  contagion  in  phthisis.  For  the 
public  was  very  selfish  and  quick  to  take  alarm,  and  if 
once  people  became  convinced  that  there  was  a  real 
danger  of  contagion  in  this  disease,  they  might  run  to 
the  extreme^  and  shun  the  consumptive  as  they  would  a 
leper.  A  patient  with  phthisis  should  always  sleep  alone, 
in  a  well-ventilated  room.  Especial  care  should  be 
taken  in  the  case  of  patients  with  the  buccal,  pharyngeal, 
or  laryngeal  forms  of  tuberculosis,  and  it  would  be  well 
for  these  to  inhale  iodoform  vapor,  in  order  to  render 
their  breath  as  innocuous  as  possible.  Children  con- 
valescing from  measles  and  bronchitis  of  the  smaller  tubes 
should  be  kept  away  from  association  with  consumptives. 
Patients  should  be  forbidden  to  expectorate  in  their 
handkerchiefs  or  on  the  ground,  but  should  use  spittoons 
containing  some  damp  sand  or  sawdust.  The  spittoons 
should  be  washed  in  boiling  water  or  in  a  solution  of 
chloride  of  zinc,  one  ounce  to  twenty  ounces  of  glycerine 
and  water.  The  rooms  in  which  phthisical  patients  have 
died  should  be  disinfected  by  burning  sulphur,  one  ounce 
to  every  cubic  yard. 

Finally  M.  Vallin  summed  up  the 

CONCLUSIONS   OF  THE   COMMITTEE 

briefly,  as  follows : 

1.  The  transmissibility  of  pulmonary  tuberculosis  is 
very  probable,  though  not  as  yet  indubitably  proven  by 
facts. 

2.  Isolation  of  consumptives,  in  the  same  sense  as  that  of 
patients  suffering  from  diphtheria  or  small-pox,  is  neither 
necessary  nor  desirable.  Yet  in  view  of  the  probable 
contagiousness  of  the  disease,  the  public  should  be  urged 
to  adopt  certain  prophylactic  measures  similar  to  those 
enunciated  in  the  body  of  the  report. 

The  Society  then  adjourned. 


^owzspan&zncji. 


THE  PERIOD  OF  GREATEST  RISK  FROM 
CONSUiMPTION. 

To  THB  Editor  of  Thb  Mbdicax.  Rbcorix 

Sir:  In  The  Medical  Record  of  July  12th  there  is  an 
article  by  Edgar  Holden,  M.D.,  entitled  "When  are  we 
at  Greatest  Risk  from  Consumption  ?  "  He  writes  as  fol- 
lows: "Rare  facilities  for  prosecuting  an  investigation 
to  obtain  a  correct  result  have  led  me  with  considerable 
labor  to  a  conclusion  as  startling  as  I  trust  it  will  be 
found  conclusive,  viz.,  that  death  from  consumption,  in- 
stead of  being,  as  is  almost  universally  supposed,  most 
prevalent  in  early  adult  life  in  this  country  is  in  reality 
not  so,  but  grows  relatively  more  frequent  as  life  ad- 
vances.'' He  supports  this  position  with  suitable  argu. 
ments,  and  a  diagram  showing  by  figures  the  actual  and 
relative  mortality  from  the  disease  at  different  periods  of 
life.  I  do  not  object  to,  but  concur  in  his  conclusion, 
although  it  is  not  so  novel  and  consequently  so  startling 
as  he  supposes,  but  I  do  object  to  his  appropriating  with- 
out definite  acknowledgment  the  labors  of  others.  The 
subject  of  the  relation  of  age  to  consumption  was  care- 
fully examined  by  myself  for  the  Mutual  Life  Insurance 
Company  from  the  statistics  of  their  own  experience  and 
the  best  tables  of  vital  statistics  then  accessible.  The 
results  were  published  by  the  company  in  1877  m  their 
"Mortuary  Experience  of  the  Mutud  Life  Insurance 
Company  of  New  York."  The  diagram  published  by 
Dr.  Holden  is  his  own,  but  the  statistics  and  figures  on 
which  it  is  founded  are,  with  one  exception,  those  pub- 
lished in  the  above-mentioned  report  and  here  used  by 
him  without  acknowledgment.  The  one  exception  is  the 
experience  of  the  life  insurance  company  with  which  he 
is  connected.  The  statistics  of  this  company  are  valu- 
able, but  they  can  scarcely  be  supposed  to  possess,  like 
Aaron's*  serpent,  a  miraculous  power  of  swallowing  all 
the  others. 

Dr.  Holden's  words  would  seem  to  indicate  that  the 
"  considerable  labor  "  was  his  own,  the  line  of  argument 
his  own,  and  the  "startling  conclusion''  a  discovery  of 
his  own,  while  at  the  very  time  of  constructing  his  dia- 
gram he  was  using  another's  work,  and  had  before  him 
Uie  pages  elaborating  the  same  line  of  argument  and 
establishing  by  statistics  a  conclusion  which  had  been 
known  to  Laennec,  Watson,  and  Christison. 
RespectfuUy  yours, 

E.  J.  Marsh,  M.D. 

Patbxson,  N.  J.,  July  ai*  1884. 


SHALL  OFFICERS  OF  THE  ARMY  ENGAGE 
IN  PRIVATE  PRACTICE  ? 

To  THK  Editor  of  Thb  Mbdical  Rscokd. 

Sir  :  On  July  19th  you  published  in  The  Record  a  letter 
from  Dr.  John  G.  Stanton,  in  which  he  complains  of  the 
privilege  granted  officers  of  the  army  to  engage  in  private 
practice.  The  statements  which  the  doctor  makes  are 
presented  in  such  an  unfair  light  that  they  should  be  an- 
swered. It  cannot  be  done  better  than  by  giving  an 
extract  from  a  letter  written  by  Dr.  Heiskell  many  years 
ago,  when  he  was  in  charge  of  the  Surgeon-General's 
Office,  more  so  since  it  seems  that  his  opinions  have 
been  a  guide  in  matters  of  the  same  nature  ever  since. 
Dr.  Heiskell  wrote  as  follows : 

**  Whether,  by  your  expression,  *  putting  themselves  in 
competition  *  with  you,  you  mean  to  convey  anything 
more  than  that  they  comply  with  the  applications  of 
those  who  desire  their  professional  aid,  is  not  clearly 
understood.  If  neither  a  breach  of  professional  etiquette 
nor  any  improper  means  to  obtain  professional  employ- 
ment is  charged  against  them,  it  is  not  perceived  that 
this  department  can,  with  propriety,  interfere  in  the 
matter.     .     .     .     When,  therefore,  it  does  not  interfere 


August  i6,  1884.] 


THE  MEDICAL  RECORD. 


195 


with  their  military  duties,  medical  officers  have  aright  to 
give  their  professional  advice,  etc.,  to  whomsoever  they 
please,  and  they  have  always  been  permitted  to  do  so 
with  a  view  to  their  professional  advancement.  Indeed, 
at  military  posts  occupied  by  a  small  number  of  troops, 
and  where  of  course  the  subjects  of  disease  are  few  in 
number,  and  the  complaints  of  these  few  present  but 
little  variety  of  character,  it  is  rather  desirable  than  other- 
wise that  the  army  physician  should  extend  his  sphere  of 
action  to  the  citizens  immediately  around  him,  so  as  to 
become  ^miliar  with  disease  under  all  circumstances,  the 
maladies  prevailing  through  the  country  and  among  the 
dtizens  generally,  as  well  as  the  diseases  peculiar  to  the 
soldier,  or  to  military  life  in  camp  or  garrison.  To  de- 
prive the  army  surgeon  of  any  reasonable  opportunity  of 
practical  advancement  in  his  profession  would  surely  be 
inflicting  an  injury  upon  the  service  generally,  and  es- 
pecially upon  those  who  have  to  depend  upon  him  for 
professional  aid.  ...  It  may  not  be  out  of  place 
incidentally  to  state,  that  to  prohibit  a  medical  officer 
(when  his  public  duties  will  permit)  from  extending  relief 
to  those  of  his  fellow-citizens  who  may  apply  for  his  ser- 
vices— Shaving  confidence  in  his  professional  attainments 
^would  be  as  un^acious  to  them  as  it  would  be  devoid 
of  the  common  dictates  of  humanity,  and  might  afford 
as  just  and  perhaps  a  better  Cause  of  complaint  on  the 
part  of  the  neighboring  community  than  the  one  alleged 
bj  yourselves,  which  relates  exclusively  to  private  in- 
terests.    .     .     ." 

Such  was  the  language  of  an  officer  and  a  gentleman, 
addressed  to  some  physicians  at  Sackett's  Harbor,  N.  Y., 
and  the  high  social  and  professional  standing  the  officers 
of  the  medical  corps  of  the  army  have  always  enjoyed 
will  be  sufficient  proof  that  it  is  not  their  custom  "  to 
pirate  outside  of  their  posts." 

The  statement  that  there  are  too  many  surgeons  for 
the  number  of  troops  is  not  supported  by  facts.  It  is 
true  that  at  some  stations  the  garrisons  are  small,  but  not 
every  military  post  can  be  occupied  by  a  large  force. 
And  even  at  such  points  it  has  been  found  much  more 
satisfactory,  for  nulitary  reasons,  to  have  the  duties  of 
post-surgeon  performed  by  a  regular  medical  officer  or 
an  acting  assistant  surgeon,  than  to  employ  a  private 
l^jsician,  living  in  the  vicinity,  and  pay  him  for  each 
visit  Very  respectfully,  Caduceus. 


ELECTROLYSIS  IN  STRICTURES. 

To  THS  Editor  op  Thb  Mbdical  Rxcoro. 

Sir  :  In  the  issue  of  The  Medical  Record  for  July  26th, 
I  see  an  article  upon  '<  Electrolysis  in  Stricture,*'  by  Dr. 
Streeter,  of  Rochester,  N.  Y.,  which  seems  to  me  so  ar- 
bitrary in  its  dictum  regarding  the  successful  treatment 
by  the  above  process,  and  this  dictum  seems  to  be  so  en- 
tirely  based  on  the  doctor's  own  unsuccessful  experience, 
diat  I  cannot  but  attempt  a  reply. 

Having  been  the  assistant  of  Dr.  Robert  Newman  for 
the  ]ast  four  years^  both  in  dispensary  and  private  prac^ 
tice,  I  iiave  hiaul  ample  opportunity  of  convincing  myself 
that  he  (Dr.  Newman)  is  successful  with  this  method, 
whatever  experience  others  may  have.  It  is  very  com- 
mendable to  report  our  failures,  as  thereby  we  may  profit 
and  arrive  at  the  truth.  The  conclusions,  however,  and 
comments  the  doctor  arrives  at  through  his  failures  are 
opposed  to  both  logic  and  facts ;  so  that  the  paper  gives 
the  impression  as  if  it  were  a  partisan  one  and  not  simply 
in  the  interest  of  science.  If  Dr.  Streeter  does  not  suc^ 
€eed  with  electrolysis  it  does  not  follow,  by  any  means, 
that  ^erefore  electrolysis  is  a  failure,  but  the  fatdt  should 
be  looked  for  in  the  operator,  not  in  the  instrument.  If 
one  single  person  succeeds  by  the  method  (and  there  are 
icores  on  record  who  have  succeeded),  a  thousand  may 
fail,  and  without  its  affecting,  the  fact  that  it  can  be  done, 
in  the  least. 


All  recent  text-books  have  acknowledged  the  success 
of  electrolytic  treatment,  and  give  their  authorities. 
Many  respectable  practitioners  of  standing,  all  over  the 
country,  have  reported  their  cases  for  the  last  fifteen 
years,  so  that  now  it  would  be  easy  to  collect  one 
thousand  cases.  At  the  meeting  of  the  American  Medi- 
cal Association  in  Cleveland,  O.,  in  1883,  one  hundred 
successful  cases  were  reported,  which  had  been  under  ob^ 
servation  for  from  four  to  eleven  years  without  a  relapse. 
Under  such  circumstances  it  is  very  unkind  of  Dr.  Street- 
er to  say  :  "  No  recognized  authorities  upon  surgery  or 
electricity  have  reported,  etc." 

Next,  it  is  unfair  to  resuscitate  the  ten  old  cases  of 

Dr.  K ,  in  1871.     It  has  been  shown  why  these  cases 

were  not  a  success  in  The  Medical  Record  of  July  15, 
1872,  and  other  articles.  Besides,  the  present  method 
and  present  knowledge  of  the  electrolytic  process  as  ap- 
plied to  strictures  should  not  be  compared  with  the 
rudimentary  experiments  of  1871. 

Dr.  Streeter  also  says :  "  In  no  other  similar  affections — 
stricture  of  the  oesophagus,  rectum,  etc.,  have  such  re- 
sults been  claimed  for  electrolysis."  Far  firom  the  mark  ! 
They  have  been  claimed,  and  are  on  record.  Strictures 
of  the  rectum  have  been  cured  by  electrolysis  (New  Eng- 
land  Medical  Monthly,  September,  1882),  and  a  specimen 
was  presented  to  the  New  York  Pathological  Society 
on  April  10,  1872,  which  proved  not  only  the  complete 
cure  of  the  stricture,  but  also  that  not  the  slightest  relapse 
had  taken  place,  to  which  the  most  learned  and  critical 
audience  present  could  not  take  exception. 

Butler  and  others  have  cured  stricture  of  the  oesophagus 
beyond  any  doubt,  and  even  strictures  of  the  Eustachian 
tubes  have  been  treated  successfully  by  M.  J.  Merd^  in 
the  clinic  of  Dr.  D^sardnes  (Medical  News^  quarterly 
epitome,  March,  1883).  The  method  of  Dr.  Goruki  for 
nasal  strictures,  as  also  that  for  those  of  the  lachrymal 
ducts,  are  on  record. 

As  to  the  operation  of  cutting  strictures  for  a  cure.  Dr. 
Streeter  cannot  assert  that  he  cured  them  permsmently, 
he  is  only  able  to  say  he  thinks  he  cured  them,  which  b  a 
praiseworthy  modesty. 

The  success  of  electrolysis  in  the  cure  of  strictures  is 
such  an  established  fact  now,  and  proven  by  so  man^ 
successful  cases  on  record,  and  many  more  joyful  spea- 
mens  of  humanity  who  own  a  restored  urethral  calibre, 
that  these  few  words  are  simply  meant  tC  correct 
some  misleading  statements  made  in  the  article  of  July 
26th. 

Yours  truly, 

G.  C.  H.  Meier,  M.D. 

Nbw  York  City. 


%xmQ  g^etuB* 


Official  List  of  Changes  in  ihs  StaHont  and  Duties  of  Officers 
serving  in  the  Medical  Department ,  Uniied  States  Army^ 

from  August  3  to  August  9,  1884. 

Gibson,  J.  R.,  Major  and  Surgeon.  Granted  leave 
of  absence  for  one  month  and  fifteen  days.  S.  O.  36, 
Headquarters  Division  of  the  Atlantic,  August  4,  1884. 

Heizmank,  C.  I..,  Captain  and  Assistant  Surgeon. 
Relieved  from  duty  at  Columbus  Barracks,  Ohio,  and 
ordered  for  duty  in  Department  of  the.  East.  S.  O.  i8o, 
par.  2,  A.  G.  O.,  August  2,  1884. 

McCreery,  George,  First  Lieutenant  and  Assistant 
Surgeon.  Leave  of  absence  extended  two  months.  S.  O. 
180,  par.  4,  A.  G.  O.,  August  2,  1884. 

Hopkins,  W.  E.,  First  Lieutenant  and  Assistant  Sur- 
geon. Granted  one  month's  leave  of  absence  with  permis- 
sion to  apply  for  one  month's  extension.  S.  O.  67,  par.  i. 
Headquarters  Department  of  Arizona,  August  i,  1884. 


196 


THE  MEDICAL  RECORD. 


[August  16,  1884. 


pcedical  Stjema. 


Contagious  Dissasbs — Weekly  Statement. — Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  August  9,  X8S4 : 


Week  Ending 


Casts. 

August  2,  1884 
August  9, 1884. 

Deaths, 
August  2,  1884 
August  9, 1884. 


35' 

35 


i 


22 
28 


I 


Chloral-quinine.  —  A  compound  of  quinine  with 
chloral  hydrate  has  been  made  by  Dr.  Mazzara  by  add- 
ing the  chloral  to  an  equivalent  quantity  of  quinine  dis- 
solved in  chloroform.  By  evaporating  the  solution  and 
redissolving  the  residue  in  ether,  the  new  compound  may 
be  obtained  in  warty  crystals,  which  are  said  to  be  vola- 
tile at  149°  C.  and  to  make  fluorescent  solutions  with 
acids. — Lancet. 

Supernumerary  Testicles. — Dr.  W.  S.  Cheesman, 
of  Auburn,  N.  Y.,  writes :  "  I  have  been  a  little  sur- 
prised to  observe  the  credence  which  The  Medical 
Record  gives  to  accounts  of  supernumerary  testicles. 
Not  one  of  these  cases  has  been  established  by  convinc- 
ing evidence.  Mere  manipulation  proves  nothing,  and 
The  Record's  informers  seem  to  have  applied  no  other 
test.  Well  do  I  recall  a  case  illustrating  the  liability  of 
even  the  most  learned  and  acute  to  self-deception  in  this 
matter.  In  December,  1879,  <^  Irishman  was  admitted 
to  Ward  6,  Bellevue  Hospital,  who,  besides  having  two 
aneurisms  of  his  aorta,  appeared  to  have  two  testicles  on 
each  side.  The  whole  resident  staff  went  wild  with  en- 
thusiasm, and  proudly  invited  some  of  the  more  dis- 
tinguished of  the  visiting  staff  to  examine  the  curiosity. 
One  and  two  at  a  time  they  came  in,  handled  the  speci- 
mens, and  went  awa^  convinced  and  awed.  Now  it 
happened  that  a  certain  surgeon,  hearing  of  the  case  and 
the  credulity  of  his  confreres  with  amazement,  demanded 
of  one  of  them  (a  great  pathologist  and  diagnostician)  if 
he  actually  believed  this  Irishman  to  have/<7f/r  testicles. 
The  other,  reaffirming  his  belief,  good-humoredly  advised 
his  interlocutor  not  to  talk  about  the  case  tiU  he  had 
examined  it ;  whereupon  the  critic  asked  to  be  led  to 
where  the  marvel  lay.  There  were  present  at  this  fiery 
trial  most  of  the  hospital  staff,  and,  I  think,  certain  of 
the  visiting  Board  also.  The  inquisitor  having  carefully 
manipulated  the  scrotum  and  its  interesting  contents, 
inquired  of  each  individual  in  turn  his  opinion  there- 
upon. When  all  had  committed  themselves  to  the 
opinion  that  the 'man  had  four  testicles,  he  called  for 
a  candle,  and  then  and  there  demonstrated  that 
two  of  the  bodies  in  question  were  encysted  hydroceles 
of  the  cord.  To  make  assurance  doubly  sure,  I  intro- 
duced a  hypodermic  needle  into  each  cyst  and  evac- 
uated its  serum,  whereupon  the  plump,  round,  Arm 
pseudo-testis  collapsed.  Since  that  afternoon  my 
opinions  as  to  superfluous  testicles  have  conformed 
strictly  to  the  teachings  of  scientific  medical  literature,  to 
the  exclusion  of  the  sensational  evidence  of  mere  man* 
ipulation,  whether  practised  by  myself  or  by  any  one  else. 
Authors  dismiss  this  subject  with  the  verdict,  Not  proven. 
It  is,  of  course,  difficult  to  understand  why,  when  women 
are  now  and  then  accorded  the  most  liberal  and  varied 
multiplication  of  their  generative  apparatus,  and  when 
men  are  occasionally  vouchsafed  that  embarrassment  of  I 


riches,  a  double  penis,  there  should  not  also  occur 
undoubted  cases  of  supernumerary  testicle.  Yet  such  is 
not  the  fact.  All  pretended  abnormalities  of  the  sort 
have,  when  submitted  to  rigid  criticism,  turned  out  to  be 
cystic  or  fatty  tumors,  or  what-not  Will  not  some  one 
come  forward  with  a  dissected  specimen  (nothing  less 
will  carry  conviction)  of  a  scrotum  containing  three  or 
more  testes,  and  enroll  his  name  beside  that  of  the  dis- 
coverer of  a  supernumerary  moon  ?  ** 

Dr.  G.  M.  Burdett,  of  Lenoirs,  Tenn.,  also  writes: 
''  An  acquaintance  of  mine  from  Georgia  has  three  tes- 
ticles, but  judging  from  his  family  none  of  them  were 
supernumerary,  according  to  Mr.  Webster's  definition  of 
the  word." 

Notes  Regarding  the  Prescription  of  Corrosive 
Sublimate. — Dr.  G.  G.  Davis,  of  Trewsbury,  N.  Y., 
writes :  "  Corrosive  sublimate,  mercuric  chloride,  pcr- 
chloride  of  mercury,  the  latest  and  best  antiseptic, 
seems  to  be  but  little  understood  by  the  profession  in  gen- 
eral Chemically,  it  is  represented  by  HgCl,,one  mercury, 
and  two  chlorine.  One  atom  of  the  latter  element,  not 
being  entirely  saturated  by  the  Hg,  tends  to  divorce  itself 
dnd  become  free,  to  which  fact  the  drug  owes  its  potency. 
Great  care  should  be  taken  in  making  it  up  into  solu- 
tions, that  the  water  should  be  filtered  and  distilled,  or 
rain  or  snow  water  used  In  aqueous  mixtures,  or  pure 
glycerine.  These  two  articles  are  the  best  vehicles,  and 
most  convenient,  and  should  always  contain*  a  little  of 
some  chloride,  as  common  salt,  hydrochloric  acid,  or 
chloride  of  ammonium,  to  keep  the  saturation  continuous. 
I  am  aware  that  physicians  prescribe  this  drug  in  altera- 
tive mixtures,  tonics  or  syrups  with  vegetable  extracts 
and  such  trash,  which  render  the  remedy  perfectly  mert 
In  fact,  I  know  of  but  two  very  simple  tinctures  in  which 
it  may  be  prescribed  and  hold  its  virtues,  viz. :  gentian 
and  cardamom.  With  tr.  ferri  chlor.  and  liq.  acidi  arseni- 
osi  of  the  new  Pharmacopceia  it  forms  a  model  remedy 
for  pernicious  anasmia.  This  is  also  a  scientific  mixture 
which  will  not  decompose,  and  is  a  fair  sample  of  a  pre- 
scription for  its  internal  administration.  I  would  again 
call  the  attention  of  the  profession  to  the  avoidance  of 
all  organic  materials  in  a  mixture  containing  corrosive 
sublimate." 

A  Case  of  Intestinal  Obstruction  from  Twisting 
OF  Gut— Autopsy.— Dr.  P.  T.  Shillock,  of  Chaska,  Minn., 
sends  the  history  of  a  case  of  intestinal  obstruction  pre- 
senting several  interesting  points.  The  patient  was  a 
single  woman  aged  twenty-eight,  previously  healthy,  who 
had  suffered  for  several  days  from  colic  and  vomiting. 
She  had  taken  several  cathartic  pills  which  acted  sharply. 
Griping  pains  and  vomiting  continued,  however,  and  she 
finally  sent  for  the  physician.  Dr.  Shillock  found  her 
suffering  from  abdominal  pains  and  tenderness,  tympa^ 
nitis,  and  vomiting.  Pulse,  100.  Symptoms  of  obstruc- 
tion gradually  became  more  and  more  marked,  and  in 
three  days  she  died  from  exhaustion.  The  use  of  mor- 
phine, anti-emetics,  stimulants,  cathartics,  and  enemata 
only  gave  temporary  reliet  Dr.  Shillock  writes  :  "  On 
autopsy  we  found  the  obstruction  to  be  caused  by  a 
double  looping  or  twisting  of  the  ileum,  just  a  short  dis- 
tance from  the  ileo-caecal  valve.  The  stomach,  small 
and  large  intestines  were  all  much  distended  with  gas. 
The  large  intestines  were  also  quite  congested,  whUe  the 
small  intestines  appeared  normal,  except  at  the  point 
where  twisting  took  place,  being  there  of  a  dark  red 
color.  No  evidence  of  peritonitis  was  present,  and  all 
the  other  viscera  appeared  to  be  normal.  Points  of  in* 
terest  in  this  .case  that  seem  to  make  it  worthy  of  being 
reported  were  as  follows  :  i,  The  vomited  material  had 
only  a  very  slight  fecal  odor  on  the  last  two  days  of  the 
case ;  2,  apparent  slight  causation  for  such  a  serious  con- 
dition ;  3,  setting  in  of  menstruation  only  two  days  before 
her  death  ;  4,  equal  distention  of  intestines  both  above 
and  below  obstruction,  and  passage  of  flatus  during  lat- 
ter part  of  case." 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  8 


New  York,  August  23,  1884 


Whole  No.  720 


THE  NATURAL  PRODUCTION  OF  MALARIA, 
AND  THE  MEANS  OF  MAKING  MALARIAL 
COUNTRIES  HEALTHIER. 

An  Address  delivered  at  the  Eighth  Session  of 
THE  International  Medical  Congress,  Copen- 
hagen, August  12,  1884. 

By  CONRAD  TOMMASI  CRUDELI,  M.D., 

PROFBSSOR  OF  HYCIKNB,   UNIVBXSITY  OP  ROMK»  ITALY. 

(Special  for  Thb  Mkdical  Record.) 

Gentlemen  :  Before  entering  upon  my  subject  I  must 
crave  the  indulgence  of  those  of  ray  colleagues  whose 
language  I  have  borrowed  for  any  Italicisms  that  I  may 
Q$e,  as  well  as  jfor  the  foreign  accent  which  must  strike 
their  ears -more  or  less  disagreeably.  Desiring;  to  re* 
spond  as  well  as  lay  in  my  power  to  the  invitation  with 
tdiich  I  have  been  honored  to  discuss  the  hygienic  ques- 
tions relating  to  malaria,  I  have  chosen  the  French 
language  as  being  the  one  in  which,  apart  from  my 
fflotber  tongue,  I  could  express  myself  with  the  greatest 
ease  and  precision. 

I  shall  be  pardoned  also,  I  hope,  for  having  employed 
the  terms  "  nudaria  "  and  "  malarial  districts  "  in  place  of 
the  more  commonly  used  expressions  <' paludal  miasm'' 
(masM€ paludeai)  and  "marshy  regions  "  (contries  mar^" 
cageuses).  The  substitution  is  not  a  happy  one  from  a 
literary  point  of  view,  but  I  have  made  it  deliberately  and 
for  the  following  reason :  The  idea  that  intermittent  and 
pernicious  fevers  are  engendered  by  putrid  emanations 
from  swamps  and  marshes  is  one  of  those  semi-scientific 
assumptions  which  have  contributed  most  to  lead  astray 
the  investi^tions  of  scientists  and  the  work  of  public 
administrations.  This  idea,  so  widespread  and  so  well 
established  by  the  traditions  of  the  school,  is  radically 
fiJse.  The  specific  ferment  which  engenders  those  fevers 
by  its  accumulation  in  the  atmosphere  which  we  breathe 
is  not  exclusively  of  paludal  origin,  and  still  less  is  it  a 
product  of  putrefaction.  Indeed,  in  every  region  of  the 
globe  between  the  two  arctic  circles  there  are  swamps 
and  marshes,  steeping-tanks  of  hemp  and  flax,  large 
deltas  where  salt  and  fresh  waters  mix,  and  yet  tiiere  is 
no  malaria  there,  although  putrid  decomposition  is  on 
every  side.  On  the  other  hand,  in  the  same  parts  of  the 
globe  there  are  places  whicb  are  not,  and  never  were 
marshy,  and  in  which  tbcvc  is  not  the  least  trace  of 
putrelactioD,  but  which,  nevertheless,  produce  malaria  in 
abundance.  I  reject,  therefore,  wholly  the*  paludal  as- 
sumption, and  in  order  to  express  this  view  in  the  title 
of  my  paper,  have  been  forced  to  employ  terms  which  to 
my  hearers  may  sound  like  Italicisms. 

The  Italians  generally  have  not  this  paludal  notion,  for 
experience  taught  them  long  ago  that  malaria  is  produced 
Dcady  everywhere;  in  marshy  districts  as  well  as  in 
those  which  m^ht  almost  be  called  arid ;  in  a  volcanic 
soil  as  well  as  in  the  deposits  of  the  miocene  and  plio- 
cene periods  and  the  ancient  and  modem  alluvia ;  in  a 
soil  rich  in  organic  matters  as  well  as  in  one  containing 
ahnost  none ;  in  the  plains  as  well  as  on  the  hills  or 
mountains.  The  word  malaria  (bad  air),  which  it  is  the 
sad  privilege  of  Italy  to  have  lent  to  all  languages  to  ex- 
press the  cause  of  intermittent  and  pernicious  fevers, 
represents  then,  among  the  majority  of  our  rural  popula- 


tions, the  idea  of  an  agent  which  may  infect  any  sort  of 
country,  whatever  may  be  its  hydraulic  and  topographical 
conditions  and  whatever  may  be  its  geological  formation. 
This  word,  therefore,  is  the  one  best  suited  to  designate 
this  specific  ferment  in  question,  and  I  have  on  this  ac- 
count employed  it  and  its  adjectival  derivatives  in  order 
not  to  resuscitate  the  idea  of  the  exclusively  paludal 
origin  of  the  morbific  agent. 

I  shall  not  tarry  long  to  speak  of  the  nature  of  this  fer- 
ment, for  the  studies  bearing  upon  that  point,  although 
far  advanced,  are  not  yet  completed.  I  may  remark, 
however,  that  the  idea  that  the  ferment  is  formed  of  liv- 
ing organisms  is  a  very  old  one,  and  has  not  arisen  sud- 
denly because  of  the  modem  theories  of  the  parasitic  na- 
ture of  disease.  From  the  time  of  Varrar  (who  believed 
that  malaria  was  made  up  of  invisible  mites  suspended  in 
the  atmosphere^  to  our  own  day  this  theory  has  been 
several  times  advanced  by  hygienists.  Independently  of 
the  general  considerations  which  led  Rasori,  and  later 
Henle,  to  formulate  the  doctrine  of  the  coniagium  vivum 
of  infection  (long  before  the  progress  of  microscopical 
science  had  revealed  the  existence  of  living  ferments)^ 
there  were  peculiar  circumstances  as  regards  malaria 
which  should  have  impelled  minds  to  look  m  that  direc- 
tion, even  in  times  long  past. 

Some  of  these  circumstances  are  of  a  nature  to  strike 
every  serious  observer,  and  deserve  a  few  moments'  at- 
tention. How  could  one  maintain,  for  example,  that 
this  ferment  is  a  product  of  chemical  reactions  taking 
place  in  the  ground,  when  it  is  seen  to  remain  constantly 
the  same  whatever  may  be  the  composition  of  the  soil 
from  which  it  emanates  I  As  long  as  the  paludal  theory 
held  sway  the  chemical  interpretation  of  this  identity  of 
the  product  in  every  latitude  was  easy.  Rica  does  not 
hesitate  to  admit  that  when  a  swampy  tract  is  heated  by 
the  sun's  rays  to  the  necessary  point  for  the  putrid  de- 
composition of  the  organic  matters  contained  in  it,  the 
"chemical  ferment,"  or  rather  the  "mephitic  gases,"  to 
which  is  attributed  the  morbific  action,  are  developed, 
whatever  may  be  the  distance  from  the  equator  at  which 
this  marshy  region  lies.  But  since  it  has  been  ascer- 
tained that  malaria  is  produced  in  soils  of  the  most  varied 
chemical  composition,  the  persistent  identity  of  this  pro- 
duct has  become  chemically  inexplicable ;  while  it  is 
however  readily  conceivable,  if  one  admits  that  malaria 
is  an  organized  ferment  which  easily  finds  the  necessary 
conditions  for  its  life  and  multiplication  in  the  most 
varied  soils,  as  is  the  case  with  millions  of  other  organ- 
isms vastly  superior  to  the  mdiraentary  vegetables  which 
constitute  the  living  ferments. 

The  same  thing  may  be  said  ol  the  progressive  inten-^ 
sity  of  the  morhtfic  production  in  abandoned  malarious 
districts^  This  fact  has  been  historically  proven  in  sev- 
eral parts  of  the  earth,  and  especially  in  Italy.  A  large 
number  of  Grecian,  Etruscan,  and  Latin  cities,  even  Rome 
itself,  sprang  up  in  malarious  territories  and  attained  a 
hi|^h  state  of  prosperity.  First  among  the  reasons  for 
this  success  must  be  placed  the  works  undertaken  with  a 
view  of  rendering  these  places  more  salubrious,  and 
which  lessened  the  evil  production,  but  almost  never  ex^ 
tinguished  it  completely.  After  the  abandonment  of  these 
localities,  the  production  of  malaria  recommenced  in  a 
degree  which  went  on  increasing  from  age  to  age,  and 
which  has  rendered  some  of  these  places  actually  unin- 
habitable. This  was  seen,  in  the  time  of  the  ancient 
Romans,  in  Etruria,  when  it  was  conquered  and  laid 


198 


THE  MEDICAL  RECORD. 


[August  23,  1884. 


waste,  and  in  several  parts  of  Magna  Grascia,  and  of 
Sicily.  From  the  fall  of  Rome  even  to  the  present  day, 
this  phenomenon  has  been  manifested  in  a  very  evident 
manner  in  the  Roman  Campagna,  in  certain  parts  of 
which,  even  up  to  the  time  of  the  Renaissance,  it  was 
possible  to  maintain  pleasure  houses,  but  which  are  now 
uninhabitable  during  the  hot  season.  In  many  cases 
the  physical  conditions  of  the  soil  have  undergone  no 
appreciable  change  during  centuries,  so  that  it  is  impos- 
sible to  attribute  so  enormous  an  augmentation  of  ma- 
laria to  an  increase  in  its  annual  production,  itself  in- 
creased by  a  progressive  alteration  of  the  chemical 
composition  of  the  soil.  But  if,  on  the  contrary,  it  be 
admitted  that  malaria  is  caused  by  a  living  organism 
whose  successive  generations  accumulate  in  the  soil,  the 
interpretation  of  this  fact  becomes  very  simple. 

There  are,  finally,  peculiarities  in  the  local  charging 
cf  the  atmosphere  with  malaria  which  can  be  expUuned 
only  in  this  manner.  If  the  malarial  miasm  were  com- 
posed of  gaseous  bodies  emanating  from  the  soil,  or 
rather  of  chemical  ferments  formed  beneath  the  ground 
and  raised  into  the  air  by  gases  or  watery  vapor,  the 
charging  of  the  atmosphere  with  the  specific  poison 
ought  to  arrive  at  its  maximum  during  the  hottest  part 
of  the  day,  when  the  ground  is  heated  the  most  by  the 
sun*s  rays  and  when  the  evaporation  of  water  and  all 
chemical  actions  attain  their  maximum  intensity.  But 
this  is  very  different  from  what  actually  occurs.  The 
local  charging  of  the  atmosphere  is  always  less  strong 
during  the  meridian  hours  than  at  the  beginning  and  the 
end  of  the  day,  that  is  to  say,  after  the  rising,  and  espe- 
cially after  the  setting,  of  the  sun.  Now  it  is  precisely 
at  these  hours  that  the  difiference  between  the  tempera- 
ture of  the  lower  layers  of  the  atmosphere  and  that  of 
the  surface  of  the  ground  is  the  greatest,  and  that  the 
ascending  currents  of  air  starting  from  the  ground  are 
the  strongest.  If  malaria  consists  of  solid  particles  con- 
tained in  the  soil,  one  may  readily  understand  how  their 
elevation  en  masse  into  the  atmosphere  should  take 
place  especially  at  these  two  periods  of  the  day. 

All  these  facts,  which  can  be  easily  verified  if  the 
subject  of  malaria  be  studied  on  the  spot  and  without 
any  preconceived  notions,  explain  the  tendency  whicli 
has  always  been  manifested  to  attribute  this  specific 
poisoning  of  the  air  to  a  living  organism  which  is  multi- 
plied in  the  soil ;  and  they  also  explain  the  ardor  with 
which  hygienists  have  applied  themselves  to  the  produc- 
tion of  the  scientific  proof. 

Unfortunately  the  investigations  undertaken  for  this 
end  have  for  a  long  time  been  fruitless,  for  the  precon- 
ceived paludal  theory  has  led  investigators  to  occupy 
themselves  exclusively  with  the  inferior  organisms  in- 
habiting marshes.  Among  these  organisms  they  studied 
especially  the  hyphomycetes^  which  had  already  acquired 
so  great  an  importance  in  dermatology ;  and  their  entire 
attention  was  concentrated  upon  the  aquatic  algae,  with- 
out even  taking  the  precaution  to  determine  whether  the 
varieties  which  they  thought  to  be  malarial  were  found 
in  all  malarious  swamps,  or  whether  they  were  capable 
of  living  within  the  human  organism.  It  has  thus  hap- 
pened that  each  observer  has  indicated  as  the  cause  of 
malaria  a  different  variety  of  alga,  whichever  he  found  to 
be  most  abundant  in  the  swampy  ground  that  he  had  to 
examine.  Thus  Salisbury  has  indicated  the  palmella 
gemiasmay  which  is  found  with  us  in  places  perfectly  free 
from  malaria,  while  it  is  often  wanting  in  malarious 
marshes  in  the  centre  of  Italy ;  Balestra,  a  species  of 
alga  which  is  as  yet  indeterminate ;  Bargellini,  the  pal- 
moglosa  micrococca  ;  Saflford  and  Bartlett,  the  hydrogas^ 
trum  granulatum  ;  and  Archer,  the  chitonohlastus  cerugi- 
nosus.  There  is  not  a  single  one  of  these  species  the 
parasitic  nature  of  which  has  been  demonstrated ;  and 
as  regards  the  two  last  named  varieties,  it  can  be  posi- 
tively denied  that  they  are  capable  of  producing  a  general 
infection,  for  the  diameter  of  their  spores  and  filaments 
is  greater  than  that  of  the  capillary  blood-vessels. 


It  was  only  in  1879  that  Klebs  and  myself,  after  having 
been  thoroughly  freed,  by  a  long  series  of  preparatory 
studies,  from  the  unfortunate  paludal  idea,  undertook  to* 
gether  some  investigations  in  malarious  districts  of  the 
most  varied  character,  marshy  and  not  marshy.  We 
employed  the  system  of  fractional  cultivation,  making 
experiments  on  animals  with  the  final  products  thus  ob- 
tained. We  felt  ourselves  justified  in  recognizing  the 
malarial  ferment  in  the  schizomycete  bacillus.  The  nu* 
merous  researches  made  subsequently  by  us,  and  by  many 
other  observers,  in  the  soil  and  in  the  air  of  several  malari- 
ous localities,  as  well  as  in  the  blood  and  in  the  organs 
of  men  and  animals  specifically  infected,  have  put  it 
henceforth  almost  beyond  doubt  that  we  really  have  to 
do  with  a  schizomycete.  Very  recently,  MM.  Marchia 
fava  and  Celli  have  succeeded  in  demonstrating  that  the 
germs  of  this  schizomycete  attack  directly  the  red  blood- 
globules,  and  destroy  them,  causing  them  to  undergo  a 
series  of  very  characteristic  changes  which  admit  of  easy 
verification,  and  which  render  certain  the  existence  of  a 
malarial  infection. 

Several  observations  made  recently  in  Rome  tend  to 
demonstrate  that  the  schizomycete  of  malaria  does  not 
always  assume  the  complete  bacillary  form  described  by 
Klebs  and  myself;  but  this  morphological  question  pos- 
sesses no  further  interest  for  the  hygienist.  For  him  the 
essential  thing  is  to  know  that  he  has  to  deal  with  a  liv- 
ing ferment  which  can  flourish  in  ^ils  of  very  varied  com- 
position, and  without  the  presence  of  which  neither 
marshes  nor  stagnant  pools  of  water  are  capable  of  pro- 
ducing malaria. 

We  must  not  think,  however,  that  all  earth  containing 
this  ferment  is  capable  of  poisoning  the  superjacent  atmo- 
sphere. Popular  experience,  certain  modem  scientific  in- 
vestigation, and  the  facts  which  one  can  often  verify  when 
the  soil,  which  was  malarious  in  ancient  times  and  which 
has  since  ceased  to  be  so,  is  turned  up  to  a  great  depth,  all 
agree  in  proving  that  the  ground  remains  inoffensive  as 
long  as  it  is  not  placed  in  certain  conditions  indispensable 
for  the  multiplication  of  this  specific  ferment.  Up  to  this 
point  the  organism  lives,  so  to  speak,  in  an  inert  state, 
and  may  remain  so  during  centuries  without  losing  any  of 
its  deleterious  power.  There  is  nothing  in  this  fact  that 
ought  to  surprise  us,  since  we  know  that  the  life  and  the 
power  of  evolution  belonging  to  the  seeds  of  plants  of  a 
much  higher  order  than  these  vegetable  organisms  con* 
stituting  ferments,  may  remain  latent  for  centuries,  and 
may  then  revive  at  once  when  these  gi-ains  are  placed  in 
the  conditions  suitable  for  their  germination. 

Among  the  conditions  favorable  to  the  multiplication 
of  the  malarial  ferment  contained  in  the  soil,  and  to  its 
dispersion  through  the  superjacent  atmosphere,  there  are 
three  which  are  absolutely  essential,  and  the  concurrence 
of  which  is  indispensable  for  the  production  of  bad  air 
(malaria).  First,  a  temperature  which  does  not  fall  be- 
low 20°  C.  (67.5°  F.) ;  next,  a  very  moderate  degree  of 
permanent  humidity  of  the  soil ;  and  finally,  the  direct 
action  of  the  oxygen  of  the  «ir>u)>on  the  strata  of  earth 
which  contain  the  ferment.  If  a  single  one  of  these 
three  conditions  be  wanting,  the  development  of  malaria 
becomes  impossible.  This  is  a  point  of  prime  impor- 
tance in  the  natural  history  of  malaria,  and  it  gives  us 
the  key  to  most  of  the  methods  of  sanitary  improvement 
attempted  by  man. 

Let  us  see  first  what  can  be  done  in  this  direction 
without  the  labor  of  man.  For  nature  herself  makes 
localities  salubrious  by  suspending  for  a  greater  or  less 
time  the  production  of  malaria.  It  is  thus  that  winter 
brings  about  in  every  country  a  freedom  from  malaria 
which  \%  purely  thermic ^  for  it  is  due  simply  and  entirely 
to  a  sinking  of  the  temperature  below  the  required  raini- 
Indeed,  if  the  temperature  in  winter  rises  above 


mum. 


this  minimum,  there  are  often  sudden  outbrcFaks  of  ma- 
laria. Sometimes,  during  very  warm  and  dry  summers, 
the  heat  extracts  all  the  humidity  from  the  malarious 
soil,  and  thus  procures  for  us  a  freedom  from  the  disease. 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


199 


which  \% purely  hydraulic.  This  raay  continue  for  a  long 
time  (as  happened  in  the  Roman  Campagna  during  the 
years  1881  and  1882),  but  may  also  be  completely  de- 
stroyed by  a  single  shower.  Nature  also  sometimes  ren- 
ders a  district  healthy  in  a  manner  purely  atmospheric^ 
by  covering  a  malarious  soil  with  earth  which  does  not 
contain  the  malarial  ferment,  or  with  a  matting  formed 
0/  earth  and  the  roots  of  grasses  growing  closely  to- 
gether in  a  natural  meadow. 

In  the  attempts  of  purification  by  suspending  the  ma- 
larial action,  which  have  been  devised  by  man,  the  same 
thing  has  been  done ;  that  is  to  say,  it  has  been  sought  to 
eliminate  at  least  one  of  the  three  conditions  essential  to 
the  development  of  the  specific  ferment  contained  in  the 
infected  soil.  Naturally,  the^  have  not  thought  of  bring- 
ing about  a  thermic  purification,  such  as  nature  produces 
in  winter,  because  of  the  impossibility  of  moderating  the 
action  of  the  sun  ;  but  they  have  tried  from  all  time  to 
procure  hydraulic  or  atmospheric  purifications,  and 
sometimes  to  combine  these  together  in  a  very  happy 
way. 

The  hydraulic  systems  are  very  numerous,  for  the 
problem  which  is  presented,  namely,  that  of  depriving 
the  ground  of  its  humidity  during  the  hot  season,  neces- 
sitates different  solutions  accordmg  to  the  nature  and  the 
bearing  of  the  soil  Sometimes  this  is  done  by  digging 
open  or  closing  ditchest  intended  to  draw  away  large 
bodies  of  water.  At  other  times  a  system  of  drainage  is 
established,  by  means  of  which  the  water  is  drawn  out 
of  die  earth  and  its  level  is  depressed,  so  that  the  upper 
malarious  strata,  exposed  to  the  direct  action  of  the  air, 
are  deprived  of  moisture  during  the  hot  season.  This 
s}'stem  of  drainage  is  not  a  modem  invention ;  the  Italian 
monks  understood  it  as  well  as,  and  even  better  than,  we 
do.  In  deep  and  loose  soils  they  used  sometimes,  just 
as  we  do  now,  porous  clay  pipes  ;  but  when  the  subsoil 
was  formed  of  compact  and  nearly  impermeable  matters, 
they  employed  a  system  of  drainage,  the  extent  and 
grandeur  of  which  astonishes  us.  It  is  that  of  drainage 
by  cavities,  applied  by  the  Etruscans,  Latins,  and  Volsci 
to  all  the  Roman  hills  formed  of  volcanic  tufa,  the  tra- 
dition of  which  I  have  found  still  preserved  in  some 
comitries  of  the  AbruzzL 

We  may  sometimes  establish  a  double  drainage,  from 
bdow  and  from  above ;  that  is  to  say,  to  drain  the  sub- 
soil, and  at  the  same  time  increase  the  evaporation  of 
water  from  the  surface  of  the  ground.  It  is  well  known 
that  clearing  off  the  forests  of  malarious  countries  has 
often  proved  an  excellent  means  of  making  lands  salu- 
brious which  were  before  too  damp ;  for,  by  removing 
every  obstacle  to  the  direct  action  of  the  sun's  rays  upon 
the  ground,  we  cause  an  increase  of  evaporation  from  its 
surface,  and  may  thus  be  enabled  to  exhaust  the  super- 
ficial strata  completely  of  their  water  during  the  hot  sea- 
son. In  very  moist  lands  which  lend  themselves  readily 
to  deep  drainage,  the  combination  of  the  latter  with  a 
dearing  of  the  surface  has,  in  almost  every  quarter  of 
Ae  globe,  rendered  possible  a  very  widespread  and  some- 
times quite  lasting  freedom  from  malaria.  But,  although 
a  nearly  universal  experience  proclaims  this  fact,  there  is 
a  school  which,  following  in  the  footsteps  of  Lancisi, 
maintains  the  contrary  opinion,  that  it  is  necessary  to 
preserve  the  forests  in  malarious  districts,  and  even  to  in- 
crease their  extent,  since  the  trees  filter  the  infected  at- 
mosphere and  arrest  the  malaria  in  their  foliage.  This 
strange  theory  was  formulated  by  Lancisi  in  17 14,  on  the 
occasion  of  the  proposed  clearing  of  a  forest  belonging 
to  the  Caetani  family,  and  lying  between  the  Pontine 
Marshes  and  the  district  of  Cistema.  Lancisi  was  com- 
pletely imbued  with  the  paludal  notion,  and  conse- 
quently believed  that  the  very  severe  malaria  of  Cistema 
was  brought  by  the  winds  from  the  coast  marshes,  in- 
stead of  being  produced  in  the  soil  surrounding  the  dis- 
trict, which  was  then  covered  by  this  forest  He  believed 
then  that  the  forest  acted  as  a  protective  rampart,  and 
i«  prevented  its  being  cut  down.     But  toward  the  mid- 


dle of  the  present  century  the  Caetani  had  the  woods 
cleared  off  from  the  entire  belt  of  land  surrounding  Cis- 
tema. Twenty  years  later  I  was  able  to  show  that 
Cistema  had  gained  greatly  in  salubrity.  I  published  my 
observation  in  1879,  and,  naturally,  was  tsiken  %o  task 
rather  sharply  in  the  name  of  the  sacred  tradition. 
Happily  these  recriminations  led  our  Minister  of  Agri- 
culture to  have  the  question  studied  by  a  special  com- 
mission. This  commission,  after  a  conscientious  exami- 
nation  extending  over  three  years,  of  all  the  malarious 
localities  in  the  province  of  Rome,  has  just  published  its 
report,*  the  conclusions  of  which  are  entirely  in  accord 
with  the  facts  of  universal  experience.  They  were  not 
able  to  verify  a  single  fact  in  support  of  Lancisi's  theory, 
while  they  found  many  of  the  same  nature  as  that  of  Cis- 
tema, and  which  have  resulted  in  overturning  the  theory 
entirely. 

It  has  also  been  thought  possible  to  practise  drainage 
from  above  by  means  of  plantations  of  certain  trees 
which  would  draw  considerable  moisture  from  the  earth, 
a  method  which  might  really  be  serviceable  in  some 
malarious  districts.  But  in  accordance  with  the  idea  that 
malaria  is  a  product  of  paludal  decomposition,  the  trees 
selected  have  almost  always  been  the  eucalyptus.  It  has 
been  maintained  that  trees  of  so  rapid  a  growth  ought  to 
drain  the  soil  very  actively,  and  also  that  the  aroma  of 
their  foliage  ought  to  destroy  the  miasmatic  emanations.  I 
have  hitherto  been  unable  to  verify  a  single  instance  of 
the  destruction  of  malaria  by  eucalypytus  plantations, 
but  I  do  not  consider  myself  justified  in  denying  the  facts 
which  have  been  stated  by  others.  There  is  nothing  tc 
oppose  the  admission  that  these  plantations,  when  prop- 
erly made,  may  sometimes  have  been  of  great  utility.  I 
maintain  frankly,  however,  that  they  have  not  always 
been  so,  and  that  it  is  necessary  to  guard  against  the 
exaggerations  into  which  some  have  allowed  themselves 
to  fall  in  recent  times.  Such  exaggerations  might  have 
been  avoided  if,  instead  of  talking  about  these  planta^ 
tions  on  the  basis  of  a  theoretical  assumption,  the  results 
only  had  been  studied  in  places  where  the  eucalyptus 
abounds.  It  would  then  have  been  known  that  even  in 
the  southern  hemisphere,  the  original  home  of  the  euca- 
lyptus, there  are  eucalyptus  forests  which  are  very  malari- 
ous. This  fact  has  been  demonstrated  by  Mr.  Liversige, 
professor  in  the  University  ofSydney;  Australia.  Among 
us  also,  although  everybody  was  convinced  by  the  state- 
ments of  the  press  that  the  locality  of  the  Tre  Fontane, 
near  Rome,  had  been  freed  from  malaria  by  means  of  the 
eucalyptus,  people  were  disagreeably  surprised  by  an 
outbreak  of  very  grave  fever  occurring  throughout  the 
whole  of  this  colony  in  1882,  a  year  in  which  all  the  rest 
of  the  Roman  Campagna  enjoyed  an  exceptional  salu- 
brity. If,  alongside  of  these  hygienic  uncertainties,  we 
place  the  agricultural  uncertainties,  we  must  conclude  that 
it  is  necessary  to  contend  strongly  against  this  fanatical 
prejudice  in  favor  of  the  eucalyptus- tree.  These  plants 
are,  in  fact,  very  capricious  in  their  growth.  In  full 
vegetation  during  the  winter  in  our  climate,  they  are 
often  killed  instantly  by  a  sharp  winter  frost,  by  damp 
cold,  by  the  frosts  of  spring,  or  by  other  causes  which 
the  botanists  have  not  yet  been  able  to  determine.  At 
other  times,  if  the  winters  are  very  mild,  these  plants 
grow  too  rapidly  in  height  and  then  are  broken  short  oflf 
by  moderately  strong  winds.  It  should  further  be  men- 
tioned that  these  plantations  are  sometimes  very  expen- 
sive. In  fact,  if  the  earth  contains  too  much  water  it 
must  be  drained  under  penalty  of  seeing  the  roots  of  the 
eucalyptus  rot.  Then  again,  if  the  subsoil  is  compact, 
it  is  necessary  to  dig  deep  trenches  in  order  to  give  room 
to  the  long  roots  of  these  trees,  and  often  indeed  these 
trenches  must  also  be  drained,  as  is  done  for  olive-trees. 
The  conclusion  evidently  is  that  it  is  better  to  confine 
ourselves  to  hydraulic  methods  of  promoting  the  health- 
fulness  of  a  locality,  the  immediate  efifects  of  which  are 

1  D«Ua  influenza  dd  boshi  sulla  malaria  dominante  nella  regiona  maritdma  ddla 
provinda  di  Roma.    Annali  di  Agricoltura,  No.  77,  1884.    Roma  :   Eredi  Botta. 


200 


THE  MEDICAL  RECORD. 


[August  23,  1884. 


less  uncertain.  And  then,  when  the  local  conditions  are 
such  as  to  make  it  desirable  to  try  the  effects  of  plants 
possessed  of  strongly  absorbing  powers,  it  is  better  to 
choose  them  from  among  the  flora  of  our  own  hemisphere. 
This  is  more  sure  and  will  cost  less. 

Simple  hydraulic  methods  of  purification,  even  the 
most  perfect,  do  not,  however,  produce  permanent  hy- 
gienic effects,  since  the  moisture  necessary  for  the  multi- 
plication of  the  malaria  in  the  soil  is  so  slight  that  these 
effects  may  be  compromised  by  anything  whatever  that 
is  capable  of  restoring  a  moderate  degree  of  humidity  to 
the  ground  during  the  hot  season.  It  has  often  been 
thought  that  a  suspension  of  malarial  production  would 
be  better  assured  by  suppressing  at  the  same  time  the 
humidity  of  the  soil  and  the  direct  action  of  the  oxygen 
of  the  air  upon  the  superficial  strata  of  earth  which  con- 
tain the  ferment.  This  has  been  successfully  accom- 
plished by  the  system  of  overlaying  {combines).  This 
consists  in  covering  the  infected  soil  by  thick  layers  of 
uninfected  earth,  carried  there  either  by  the  muddy  waters 
of  rivers  or  by  the  hand  of  man.  At  the  same  time  the 
steady  drainage  of  the  surface  and  underground  water  is 
provided  for.  Last  year,  I  advised  our  Minister  of  War 
to  undertake  in  another  form  an  hydraulico-atmospheric 
purification  of  the  district  of  the  Janiculum  surrounding 
the  Salviati  palace  on  the  via  della  Longara,  by  draining 
the  soil  carefully  and  covering  with  a  Jayer  of  very  close 
turf  all  the  parts  of  the  surface  which  could  not  be  mac- 
adamized. It  would  seem  as  if  this  system  had  been 
rather  successful,  since  there  has  not  been  this  year  a 
single  case  of  fever  in  the  personnel  of  the  new  military 
college,  established  in  the  Salviati  palace  ;  while  in  the 
Corsimi  palace,  which  is  situated  on  the  same  side  of  the 
via  della  Longara,  but  which  looks  out  upon  that  part 
of  the  Janiculum  which  is  still  uncovered,  there  have  been 
some  fatal  cases  of  fever. 

Furthermore,  we  have  had  in  Rome,  during  the  past 
few  years,  some  very  evident  proofs  of  the  efficacy  of 
atmospheric  methods  of  purification.  I  will  confine  my- 
self to  the  relation  here  only  of  the  most  striking  instance, 
one  which  has  been  furnished  us  in  the  building  up  of 
new  quarters  of  the  city.  There  was  much  discussion  at 
first  as  to  whether  the  improvements  should  be  under- 
taken in  the  parts  where  they  now  are  or  in  the  valley  of 
the  Tiber,  for  the  uncovered  lands  of  the  Esquiline  and 
of  the  Quirinal  werer  malarious,  and,  as  nearly  everybody 
then  thought  that  the  malaria  of  Rome  was  carried  into 
the  city  from  the  coast  marshes,  it  was  supposed  that  this 
state  of  things  was  irremediable.  We  opposed  to  this 
view  the  fact  of  the  salubrity  of  the  Viminal,  which  is 
situated  between  the  Esquiline  and  the  Quirinal,  and 
which  .ou^ht  to  be  as  unhealthy  as  the  two  other  hills  were 
the  malaria  of  the  latter  imported  into  the  city  instead  of 
being  indigenous.  Believing  it  to  be  indigenous,  we 
hoped  that  by  shielding  the  surface  of  these  hills  from  the 
direct  action  of  the  air  (by  building  houses  and  paving 
the  streets),  the  malaria  would  cease  to  be  produced 
there.  That  is  precisely  what  has  happened,  for  the  new 
quarters  are  very  healthy.  But  the  malaria  is  only  held 
in  abeyance  and  is  not  definitely  overcome ;  for  if  an 
extensive  excavation  is  made  in  these  hills,  and  the  con- 
tact of  the  air  with  the  malarious  soil  is  thus  re-established, 
during  a  hot  and  damp  season,  the  production  of  malaria 
commences  anew.  A  complete  atmospheric  purification 
is  nevertheless  the  most  stable  of  all  the  methods  of  ob- 
taining a  suspension  of  malarial  production,  but  unfortu- 
nately its  realization  is  very  limited,  for  it  is  restricted  to 
inhabited  localities  and  to  sodded  surfaces. 

The  ideal  method  of  insuring  freedom  from  malaria 
should  be  to  obtain  a  permanent  immunity,  that  is,  to  be 
able  to  modify  the  composition  of  the  infected  soil  in 
such  a  way  as  to  make  it  sterile  as  regards  malaria,  with- 
out taking  from  it  the  power  of  furnishing  products  use- 
ful for  the  social  economy.  But  all  the  elements  indis- 
pensable for  obtaming  such  a  result  fail  us  utterly  just 
here.     We  do  not  yet  know  what  ought  to  be,  in  general 


tenns,  the  composition  of  a  soil  incapable  of  producing 
malaria,  yet  retaining  those  properties  which  are  suitable 
for  vegetadon.  When  we  shall  have  arrived  at  this  first 
stage,  there  will  still  be  a  long  road  to  travel ;  and  the 
most  difficult  part  will  be  to  discover  a  practical  means 
of  imparting  this  salutary  composition  to  sdl  the  numerous 
varieties  of  malarious  soils. 

Scientifically,  then,  in  the  present  state  of  our  knowl- 
edge, we  are  unable  to  affinn  anything  on  this  point 
Practically,  we  are  not  much  further  advanced.  It  is 
very  probable  that  the  combination  of  hydraulic  purifica- 
tion with  a  forced  cultivation  of  the  soU  has  sometimes 
determined  changes  in  its  composition  by  which  it  has 
been  rendered  sterile  as  regards  malaria.  If  that  has 
happened,  it  has  happened  by  chance,  and  we  are  unable 
to  reproduce  the  result  at  will ;  for  we  have  not  all  the 
data  which  might  enable  us  to  understand  how  it  has 
come  about.  Most  of  the  purifications  obtained  in  an- 
cient times,  by  means  of  forced  cultivation,  continued 
during  centuries,  have  not  been  definite  at  all,  but  the 
production  of  malaria  has  been  simply  suspended. 
Hardly  was  the  regular  cultivation  of  the  fields  inter- 
rupted than  the  production  of  malaria  recommenced. 
Among  the  numerous  examples  that  I  might  cite  in  this 
connection,  I  will  limit  myself  to  that  of  the  Roman 
Campagna.  This  seemed  to  have  been  made  perma- 
nently healthy  under  the  Antonii,  but  after  the  fall  of  the 
empire  it  began  again  to  produce  malaria,  as  if  the 
forced  cultivation  through  so  many  centuries  had  never 
been. 

One  might,  strictly  speaking,  be  content  with  such  a 
result,  and  boldly  undertake  forced  cultivation  of  all 
malarious  districts,  without  stopping  to  ascertain  whether 
the  fireedom  from  malaria  so  obtained  would  be  definite, 
or  whether  the  production  of  the  poison  were  onljr  sus- 
pended. Unfortunately  one  b  never  sure  of  arriving  at 
such  a  result,  and  no  one  can  say  d  priori  whether  the 
forced  cultivation  of  a  given  malarious  tract  will  render 
it  healthful.  It  must  always  be  remembered  that  the 
first  eflfect  of  forced  cultivation,  which  requires  an  over- 
turning of  the  soil  by  means  of  the  plough,  the  spade, 
and  the  pick,  is  an  unfortunate  one,  from  a  hygienic  point 
of  view,  whenever  we  have  to  deal  with  a  malarious 
country.  Experience  has  shown,  especially  in  Italy  and 
America,  that  this  overturning  of  the  soil  almost  invari- 
ably increases  the  local  production  of  malaria.  And  this 
can  be  readily  understood,  since  the  ploughing  and  the 
digging  in  a  soil  containing  the  specific  ferment  inaeases 
the  extent  of  surface  of  the  ground  in  immediate  contact 
with  the  atmosphere.  This  first  mischievous  effect  is 
often  gradually  weakened  by  the  continued  cultivation, 
and  may  end  by  disappearing.  At  other  times,  on  the 
contrary,  it  persist^  obstinately,  and  one  is  often  forced 
in  desperation  to  the  resolve  to  level  the  ground  again 
and  to  varnish  it,  so  to  speak,  with  a  thick  sowing  of 
grass,  if  he  wishes  to  suspend  or  weaken  the  malarial 
production. 

However,  when  the  local  conditions  will  permit,  it  is 
well  to  try  whether,  by  means  of  forced  cultivation  of 
the  soil,  it  may  not  be  possible  to  increase  the  efficacy 
of  the  hydraiUic  method  of  procuring  immunity  from 
malaria,  or  of  the  hydraulico-atmospheric  method  of 
**  overlaying."  The  moment  that  it  is  known  that  this 
cultivation  has  firequently  been  advantageous,  there 
comes  forward  a  crowd  of  social  reasons  which  induce 
us  to  attempt  it,  even  though  we  be  persuaded  that  we 
are  about  to  engage  in  a  game  of  chaiice.  But  to  dare 
to  attempt  it  is  not  all  that  is  necessary,  we  need  also  the 
possibility  of  so  doing,  and  just  here  we  find  ourselves 
in  a  vicious  circle  from  which  it  is  not  easy  to  emerge. 
Forced  cultivation  cannot  be  accompUshed  without  the 
presence  of  agriculturists  in  the  region  during  the  entire 
year ;  and  the  agriculturists  cannot  remain  in  the  region: 
during  the  fever  season,  for  they  run  thereby  too  great  a. 
risk.  For  the  solution  of  this  question  there  is  but  one- 
means  :  try  to  increase  the  power  of  resistance  of  tU 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


201 


kutMon  crganism  to  the  attacks  of  the  malaria.  It  is  to  a 
search  after  the  means  of  accomplishing  this  result  that 
I  have  devoted  myself  during  the  past  few  years. 

There  is  nothing  to  hope  for,  as  regards  malaria,  in 
acclimation.     Individual  acclimation  is,  and  always  has 
been,  impossible.     The  malarial  infection  is  not  one  of 
those  a  fiirst  attack  of  which  confers  immunity  from  other 
attacks.     It  is,  on  the  contrary,  a  progressive  infection, 
the  duration  of  which  is  indeterminate,  and  which  is  of 
such  a  nature  that  a  single  attack  may  suffice  to  ruin 
Ae  constitution  for  life.     Collective  or  racial  acclimation 
certainly  existed  in  the  past,  at  a  time  when  specific 
remedies  for  pernicious  malaria  were  unknown ;  and 
even  later,  when  the  employment  of  these  remedies  was 
very  limited.     The  acclimation  was  due  to  a  natural 
selection  made  by  the  malaria  upon  successive  genera- 
tions, from  which  it  took  away,  almost  without  opposition, 
all  those  who  possessed  but  a  feeble  individual  power  of 
resistance  to  the  specific  poison,  while  it  spared  those 
who  possessed  this  power  of  resistance   in   an  extra- 
ordinary degree.    The  first  were,  according  to  the  Gre- 
cian myth,  the  human  victims  destined  to  af pease  the 
monster y  or  demon^  who  opposed  the  violation  of  the  ter- 
ritory over  which  he  had  up  to  that  time  exercised  an 
absolute  sovereignty.    The  second  became  the  founders 
of  the  race,  and  through  them,  from  generation  to  gen- 
eration, the  collective  power  of  resistance  to  the  malaria 
was  progressively  increased.     In  our  own  days  a  like 
selection  may  take  place  among  barbarous  races,  as  it 
does  among  the  cattle  and  the  horses  in  a  malarious 
region,  but  it  has  become  an  impossibility  among  civ- 
ilized nations.     By  means  of  the  specific  remedies  which 
we  possess,  the  use  of  which  is  now  so  general,  the  lives 
of  a  laige  number  of  individuals  whose  resisting  powers 
are  very  feeble   are   preserved ;  and   these   individuals 
beget  others  whose  power  of  resistance  to  the  action  of 
the  specific   pobon  is  still  more  feeble.     This  results, 
after  a  number  of  generations,  in  the  physical  degrada- 
tion of  that  part  of  the  human  race  which  inhabits  mala- 
rious  countries. 

We  cannot,  therefore,  in  the  future,  count  upon  the  as- 
sistance of  external  natural  forces  to  increase  the  power 
of  resistance  of  human  society  against  the  assaults  of 
inalaria.  Such  an  object  can  be  obtained  only  by  artifi- 
cial means.  It  has  been  sought  to  attain  this  end  by  the 
daily  administration  of  the  salts  of  quinine,  of  the  salicy- 
lates, and  of  the  tincture  of  eucalyptus,  each  and  every 
one  tried  in  turn.  But  the  salts  of  quinine  are  dear, 
exercise  a  prompt,  though  very  transient,  anti-malarial 
action,  and,  when  administered  for  a  long  time,  disturb 
rather  seriously  the  functions  of  the  digestive  and  ner- 
vous systems.  The  salicylates,  when  well  prepared,  are 
rather  dear,  and  there  is  as  yet  no  proof  that  they  possess 
prophylactic  powers  against  malaria.  The  alcoholic 
tincture  of  eucalyptus  is  useful  in  malarious  regions  (as 
are  all  the  alcoholics,  beginning  with  wine)  in  quickening 
the  circulation  of  the  blood  ;  may  it,  perhaps,  also  act  as 
a  preservative  against  light  attacks  of  malaria?.  Possibly. 
But  it  is  very  certain  that  it  possesses  no  efficacy  in 
places  where  malaria  is  severe.  It  will  suffice  to  prove 
this  to  recall  the  two  epidemics  of  fever  which  afflicted 
the  colony  of  the  Tre  Fontane,  near  Rome,  in  1880  and 
1882.  Everybody  was  attacked,  and  there  were  several 
cases  of  pernicious  fever,  although  a  good  preparation  of 
cncal3rptus  is  manufactured  in  the  place  and  is  distributed 
largely  to  the  colonists  during  the  dangerous  season  of 
the  year. 

Haying  several  times  had  occasion  to  observe,  in 
jnalarious  regions,  that  when  recourse  was  had  to  arsenic 
m  order  to  subdue  fevers,  over  which  quinine  had  exerted 
almost  no  effect,  relapses  occurred  but  rarely  ;  and  hav- 
ing been  able  to  satisfy  myself  that  the  arsenical  treat- 
ment sometimes  procured  a  permanent  immunity  in  indi- 
viduals who  are  subject  to  frequent  attacks  of  malaria,  I 
hegan  in  1880  to  employ  arsenic  •  (arsenious  acid)  as  a 
prophylactic  in  certain  portions  of  the  Roman  Campagna. 


This  remedy  was  indicated,  in  an  experiment  of  this  sort, 
not  only  by  reason  of  its  durable  anti-malarial  effects,  but 
also  by  its  low  price,  by  the  beneficial  influence  which  it 
exerts  upon  all  the  nuditive  functions,  and  because  it  has 
no  disagreeable  taste  and  may  therefore  be  given  to 
everybody,  even  to  children.    My  first  trials  in  1880  were 
rather  encouraging,  and  I  felt  myself  justified  in  engaging 
some  proprietors  and  the  association  of  our  southern  rail- 
roads to  repeat  the  experiments  on  a  large  scale  the  fol- 
lowing year,  recommending  them,  however,  to  use  arsenic 
in  a  solid  form  as  offering  an  easy  and  certain  dosage. 
This  extensive  prophylactic  experiment  beean  in  188  i, 
and  acquired  constantly  increasing  proportions  in  1882 
and  1883,  which  have  become  still  larger  this  year.     An 
experiment  of  this  kind  is  not  easy  to  conduct  in  the  be- 
ginning.    The  name,  arsenic,  fiightens  not  only  those 
whom  we  desire  to  submit  to  its  action,  but  also  the  phy- 
sicians, whose  exaggerated  fears  have  sometimes  ren- 
dered the  experiments  of  no  avail,  since  they  were  con- 
ducted too  timidly  and  the  doses  of  arsenic  employed 
were  altogether  insufficient.     But  some  intelligent  men, 
especially  M.  Ricchi,  physician-in-chief  to  the  southern 
railroads,  were  able  speedily  to  triumph  over  these  ob- 
stacles, and  to  place  the  experiment  on  a  firm  basis. 
The  general  testimony  of  all  the  facts  which  they  have 
collected  tends  really  to  prove  that,  when  the  administra- 
tion of  arsenic  is  begun  some  weeks  before  the  presumed 
season  for  the  appearance  of  the  fever,  and  when  it  is 
continued  regularly  throughout  the  whole  of  this  season, 
the  power  of  resistance  of  the  human  organism  to  malaria 
is  increased.     Many  individuals  gained  thereby  a  com- 
plete immunity,  others  a  partial  immunity,  that  is  to  say, 
they  were  sometimes  attacked  by  the  fever,  but  it  never, 
even  in  very  malarious  districts,  assumed  a  pernicious 
form,  and  was  easily  subdued  by  very  moderate  doses  of 
quinine.    Last  year,  for  example,  in  the  district  of  Borino, 
where  the  malaria  is  very  severe,  .M.  Ricchi  experimented 
upon  seventy-eight  employees  of  the  southern  railroads, 
dividing  them  into  two  equal  divisions,  one  of  which  re- 
ceived no  prophylactic  treatment,  while  the  other  was 
submitted  to  a  systematic  arsenical  treatment.     At  the 
end  of  the  fever  season  it  was  found  that  several  em- 
ployees among  the  first  half  had  been  attacked  by  fevers 
of  a  severe  type  ;  while  thirty-six  of  those  in  the  second 
division  had  enjoyed  a  complete  immunity,  the  three 
others  having  been  attacked,  but  so  lightly  that  they 
cured  themselves  by  quinine  without  seeking  medical  aid. 
Facts  of  this  sort  are  very  encoiuuging,  and  the  more 
so  as  the  general  health  of  those  submitted  to  the  prophy- 
lactic treatment  was  much  improved.     It  was  found  al- 
most invariably,  upon  the  termination  of  the  experiment, 
that  there  had  been  an  increase  in  bodily  weight  and  an 
amelioration  of  the  anasmia  which  is  so  common  in  ma- 
larious districts.     But,  in  order  to  arrive  at  such  results, 
it  is  necessary  to  be  at  once  bold  and  prudent     On  the 
one  hand,  it  is  necessary  to  graduate  very  carefully  the 
daily  dose,  never  exceeding  at  the  commencement  the  dose 
of  two  milligrammes  ( ^ f  ^  grain)  per  diem  for  adults,  and 
never  giving  the  arsenic  upon  an  empty  stomach.     On 
the  other  hand,  it  is  necessary  to  gradually  push  the  dose 
up  to  ten  or  twelve  milligrammes  (^^  or  -^^  grain)  a 
day  for  adults,  in  districts  where  the  malaria  is  very 
severe,  giving  the  arsenic  in  such  a  way  that  there  is 
never  an  accumulation  of  the  drug  in  the  stomach.   Most 
of  the  experiments  which  have  been  undertaken  this  year 
are  being  conducted  on  this  plan,  and  there  is  reason  to 
hope  that  they  will  give  satisfactory  results. 

We  must  not,  however,  rest  here  if  we  wish  to  attain 
promptly  the  end  proposed,  namely,  that  of  planting 
colonies  in  malarious  districts  without  exposing  the  colo- 
nists to  grave  danger.  Even  if  we  realize  perfectly  the 
hope  which  I  conceived  in  1880,  and  if  we  are  enabled 
to  prove  that  arsenic  increases  man's  power  of  resistance 
to  the  assaults  of  malaria,  we  must  not  imagine  that  every- 
thing is  accomplished.  It  will  take  a  long  time  before 
the  use  of  a  preservative  method  of  this  kind  becomes 


202 


THE  MEDICAL  RECORD. 


[August  23, 1884. 


generalized,  we  have  first  to  contend  against  the  fear 
which  nearly  every  one  experiences  when  arsenic  is  men- 
tioned, and  then  there  will  also  be  difficulty  in  establishing 
everywhere  a  proper  control  over  its  administration.  In 
every  attempt  at  the  colonization  of  malarious  regions  it 
will  be  necessary  to  combat  for  a  long  time  the  diseases 
caused  by  malaria,  and  we  must  seek  for  a  method  of 
combating  them  by  a  means  which  is  in  the  possession 
of  everybody,  and  which  shall  not  be  dangerous  to  the 
general  economy  of  the  human  organism.  Those  who 
do  not  know  from  actual  experience  the  miseries  of  a 
malarious  country,  think  only  of  combating  the  acute 
forms  of  infection,  which  often  place  the  patient  in  dan- 
ger of  4eath.  But  this  danger,  though  great,  is  for  the 
most  part  imaginary,  provided  that  assistance  be  obtained 
in  time.  But  that  which  desolates  families,  and  which 
causes  a  physical  degradation  of  the  human  race  exposed 
to  the  attacks  of  malaria,  is  the  chronic  poisoning,  which 
undermines  the  springs  of  life  and  produces  a  slow  but 
progressive  anaemia.  This  infection  often  resists  all 
human  therapeutic  measures,  and  is  even  aggravated  by 
the  use  of  quinine,  which  is  given  during  the  recurrent 
paroxysms  of  fever.  Quinine  is,  when  given  for  a  long 
period  of  time,  a  true  poison  to  the  vaso-motor  nerves. 
The  question,  then,  is  to  replace  quinine,  and  the  alka- 
loids which  possess  an  analogous  physiological  action,  by 
an  agent  the  efficacy  of  which  against  chronic  malarial 
poisoning  may  be  greater  and  the  dangers  of  its  employ- 
ment less. 

A  happy  chance  has  led  Dr.  Magliori  to  the  discovery 
of  an  agent  of  this  sort,  which  was  traditionally  in  use 
by  certain  Italian  families.  It  is  an  exceedingly  simple 
thin^ — merely  a  decoction  of  lemon.  It  is  prepared  by 
cutting  up  one  lemon,  peel  and  all,  into  thin  slices, 
which  are  then  put  into  three  glassfuls  of  water  and  the 
whole  boiled  down  to  one  glassful.  It  is  then  strained 
through  linen,  squeezing  the  remains  of  the  boiled  lemon, 
and  set  aside  for  some  hours  to  cool.  The  whole  amount 
of  the  liquid  is  then  taken  fasting.  It  is  well  known 
that  in  Italy,  Greece,  and  North  Africa,  they  often  use 
lemon  juice,  or  a  decoction  of  lemon  seeds,  as  a  remedy 
in  malarial  fevers  of  moderate  intensity ;  and  in  Guada- 
loupe  they  use  for  the  same  purpose  a  decoction  of  the 
bark  of  the  roots  of  the  lemon  tree.  All  these  popular 
practices  tend  to  show  that  the  lemon  tree  produces  a 
febrifuge  substance,  which  resides  in  all  parts  of  the 
plant,  but  which  would  seem  to  be  most  abundant  in  the 
fruit.  In  fact,  among  the  popular  remedies  employed 
against  malarial  infection,  that  which  I  have  just  de- 
scribed is  the  most  efficacious,  for  it  can  be  employed  with 
good  effects  in  acute  fevers.  But  it  is  especially  advan- 
tageous in  combating  the  chronic  infection,  which  is  re- 
bellious to  the  action  of  quinine,  and  in  removing  or 
moderating  its  deplorable  effects. 

Hardly  had  I  learned  of  this  method  of  .medication, 
when  I  hastened  to  induce  some  proprietors  in  the  Ro- 
man Campagna  to  try  it  with  their  farm  hands ;  and,  af- 
ter witnessing  the  good  results  there,  I  endeavored  to 
persuade  practitioners  to  make  a  trial  of  the  same  treat- 
ment. I  was  ridiculed  a  little  at  first,  for  they  thought 
it  rather  singular  that  a  professor  should  be  trying  to 
popularize  an  old  woman's  remedy.  In  reply  to  that  I 
answered  that  practical  medicine  would  not  have  existed, 
had  it  not  known  how  to  treasure  up  from  age  to  age 
the  facts  of  popular  experience  ;  and  I  ventured  to  re- 
mark that,  had  the  Countess  de  Chinchon  waited  until 
methodical  researches  had  been  made  into  the  physio- 
logical action  of  cinchona  bark,  before  popularizing  the 
remedy,  the  use  of  which  she  had  learned  from  the  semi- 
barbarous  Peruvians,  in  all  probability  humanity  would 
still,  as  regards  nmlaria,  be  dependent  upon  the  medica- 
tion practised  in  the  middle  ages.  Happily  these  argu- 
ments had  the  desired  effect  upon  certain  distinguished 
practitioners,  some  of  whom,  especially  in  Sicily  and 
Tuscany,  have  already  collected  together  a  tolerably 
large  number  of  very  encouraging  observations.      One 


of  them.  Dr.  Mascagni,  of  Avezzo,  tried  the  remedy  ii\ 
his  own  person,  and  succeeded  in  promptly  curing  an 
obstinate  malarial  fever  which  had  resisted  the  action  of 
quinine. 

Gentlemen,  in  dealing  with  malaria  we  ought  always  to 
hold  popular  experience  in  high  esteem,  for  we  owe  much 
to  it.     We  owe  to  it  the  fact  that  we  have  been  liberated 
from  the  paludal  idea,  and  furthermore,  that  we  have 
learned  that  it  is  often  better,  instead  of  trying  to  pre- 
vent the  importation,  for  the  most  part  imaginary,  of 
malaria  from  distant  marshes,  to  suppress  its  production 
in  the  soil  under  our  feet  or  in  that  immediately  sur- 
rounding us.    We  owe  to  it  the  knowledge,  which  we 
now  have,  that  malaria  rises  up  into  the  atmosphere  only 
to  a  limited  height,  so  that  by  placing  ourselves  a  little 
above  this  limit  in  order  to  eliminate  the  possibility  of 
the  malaria  being  carried  up  to  us  by  oblique  atmospheric 
currents,  we  are  enabled  to  breathe  an  air  which  does 
not  contain  this  ferment,  or  which  contains  it  only  in  in- 
significant amounts ;   thus  one  may  even  sleep  in  the 
open  air  during  the  night  in  very  unhealthy  districts  with- 
out running  any  risks.     The  knowledge  of  this  fact  has 
led  some  peoples  of  Greece,  and  the  inhabitants  of  the 
Pontine  Marshes,  to  sleep  in  the  open  air  on  platforms 
raised  on  poles  four  or  five  metres  (twelve  to  fifteen  feet) 
in  height.     Some  people  in  the  Roman  Campagna  have 
built  houses  for  themselves  on  top  of  the  ancient  tombs, 
the  walls  of  which  are  perpendicular ;  the  American  In- 
dians fasten  their  hammocks  as  high  up  as  possible  to  the 
trees  of  the  malarious  forests;  and  very  recently,  the 
en^eers  of  the  Panama  Railroad  had  little  wooden  huts 
built  in  the  trees  in  order  to  procure  safety  against  the 
terrible  outbreak  of  malaria  which  occurred  during  the 
construction  of  that  iron  way.     We  owe,  finally,  to  this 
popular  experience  the  discovery  of  the  specific  action  of 
quinine,  and  the  consequent  preservation  of  thousands  and 
thousands  of  human  lives.     Why  should  we  reject  a  priori 
and  without  investigation  other  useful  data  which  it  may 
yet  present  to  our  consideration  ?     If  we  wish  to  make 
progress  in  this  question  of  rendering  malarious  countries 
healthy,  we  must  always  hold  before  our  eyes  a  double 
object :  to  find  a  means  of  prophylaxis  which  may  be 
accessible  to  everybody ;  and,  at  the  same  time,  to  find 
a  means,  equally  within  everybody's  reach,  to  overcome 
chronic  msdarial  poisoning  and  its  evil  consequences. 
Science  is  still  too  far  behind  to  permit  us  to  hope  that 
we  shall  soon  succeed  in  discovering  this  second  means  by 
purely  scientific  researches.  We  ought,  therefore,  to  gather 
together  with  great  care  all  the  facts  which  point  to  the 
possibility  of  a  solution  of  this  problem,  and  if  the  measures 
to  which  these  facts  point  seem  to  be  incapable  of  doing 
harm,  we  ought  to  try  tnem  boldly,  and  not  be  restrained 
by  a  false  idea  of  the  dignity  of  science.     The  social  im- 
portance of  the  problem  is  too  great  to  allow  of  its  solu- 
tion being  retarded  by  the  fear  that  scientific  men  may 
be  accused  of  having  been  outrun  by  the  ignorant.    True 
science  has  none  of  these  puerile  susceptibilities ;  on  the 
contrary,  it  deems  it  an  honor  to  be  able  to  seize  all  the 
observations  of  fact,  whoever  may  have  been  their  first 
recorder,  to  put  them  to  the  crucial  test  of  methodical 
experiment,  and  to  convert  them  into  a  new  stepping- 
stone  on  the  march  of  human  progress. 


Typhoid  Fever  and  Tuberculosis. — Dr.  Gral  denies 
the  existence,  advanced  by  some  authors,  Of  an  antagonism 
between  tuberculosis  and  typhoid  fever.  If  typhoid  fever, 
he  says,  attacks  a  tuberculous  subject,  it  does  not  run 
an  abnormal  course,  but  the  tuberculosis  assumes  an 
acute  character  in  consequence.  Typhoid  fever  may  be 
a  cause  of  tuberculosis  by  creating  a  predisposition  in 
the  patient  to  this  disease.  In  the  stage  of  convales- 
cence especially,  the  tubercular  process  often  becomes 
verjr  2s:i\\^n'^  Deutsche  Medicinal  -  Zeitungy  June  2, 
1884. 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


203 


FOOD  RATIONS,  IN  HEALTH  AND  DISEASE, 
OF  PERSONS  CONFINED  IN  THE  HOSPI- 
TALS. INFIRMARIES,  AND  PRISONS  OF  DIF- 
FERENT COUNTRIES. 

Ak  Address  Delivered  at  the  General  Session 
OF  the  International  Medical  Congress,  Co- 
penhagen, August  15,  1884. 

By  Professor  P.  L.  PANUM,  M.D,, 

COPKMHAGKN,  DENMARK. 

(Special  for  The  Msdical  Rboord.) 

Physicians  have  hitherto  devoted  loo  little  attention  to 
the  study  of  the  proportions,  both  absolute  and  relative,  of 
the  albuminoid  matters,  fats,  and  hydrocarbons  contained 
in  the  diet  of  the  sick,  the  infirm,  and  prisoners,  as  well 
as  in  the  separate  dishes  of  which  this  diet  is  composed. 
A  knowledge  of  these  proportions  is  indispensable  in  es- 
tabbshing  a  rational  dietetic  regime  for  the  sick,  and  also 
in  determining  whether  the  food,  which  is  supplied  ac- 
cordinf  to  fixed  rules  to  the  inmates  of  public  institu- 
tions, IS  of  a  sufficiently  nourishing  character. 

The  objections  which  have  been  raised  against  the  cor- 
rectness of  the  average  food  rations,  established  by  Voit 
and  other  physiologists  as  suitable  for  healthy  individuals 
in  good  nutritive  condition,  are  not  well  founded.  The 
determination  of  the  quantity  of  the  albuminoid  sub- 
stances, fats,  and  hydrocarbons  contained  in  the  regular 
diet  lists  of  hospitals,  infirmaries,  etc.,  is  a  powerful 
means  of  effecting  improvements  and  reforms  in  the  ali- 
mentation of  the  individuals  supported  in  these  institu- 
tions. But  it  is  essential  in  all  such  calculations  to  ob- 
serve every  precaution  necessary  in  order  to  obtain 
comparative  results.  Similar  calculations  regarding  the 
different  varieties  of  diet  of  patients  confined  in  hospitals 
would  be  of  great  value  as  a  means  of  recognizing  and 
estimating  the  differences  of  opinion  which  still  obtain 
concerning  the  alimentation  of  the  sick,  among  phy- 
sicians of  the  present  day,  in  various  countries. 

Convinced  of  the  great  importance  of  this  subject,  the 
author  advanced  the  following  propositions  : 

Firs/, — Endeavor  to  obtam  information  as  complete 
as  possible  concerning  the  rations  furnished  to  the 
healthy,  or  relatively  healthy,  inmates  of  hospitals,  in- 
finnanes,  and  prisons,  as  well  as  to  the  soldiers  and  sail- 
ors of  different  countries. 

Second, — Endeavor  to  obtain,  by  means  of  similar  in- 
formation, and  with  the  assistance  of  the  hospital 
authorities  in  the  different  countries,  comparative  tables 
of  the  proportions  of  albuminoid  substances,  fats,  and 
hydrocarbons  contained  in  the  regular  diet  lists,  together 
with  the  indications  for  the  employment  of  one  or  the 
other  kinds  of  diet  as  used  in  the  hospitals. 

'Hiird, — It  would,  however,  be  necessary  to  know  first 
of  all :  (a^  whether  the  individuals  living  upon  a  regulated 
form  of  diet  are  ever  given  any  other  food,  whether  this 
extra  nutriment  is  given  with  regularity  or  not,  and 
whether  or  not  the  amount  of  food  so  given  can  be  de- 
termined with  accuracy ;  {b)  whether  the  distribution  of 
these  rations  is  so  systematized  that  there  is  nothing  in  ex- 
cess from  which  the  hospital  officers  or  attendants  may 
derive  an  illegal  profit ;  (c)  whether  the  distribution  is  as 
just  and  equally  proportioned  as  possible,  and  finally, 
whether  the  food  for  the  attendants  is  prepared  in  other 
vessels  than  is  that  for  the  patients. 

Fourth. — Obtain  information  as  to  the  system  em- 
ployed to  control:  {a^  the  good  quality  of  the  ingredients, 
and  {ff)  the  preparation  and  distribution  of  the  food. 

Fifth. — Insist  upon  the  necessity  of  according  to  the 
physicians  unrestricted  liberty  in  the  regulation  of  the 
absolute  and  relative  proportions  of  albuminoid  sub- 
stances, fats,  and  hydrocarbons  which  should  be  con- 
tained in  the  hospital  diet.  This  liberty  should  be 
absolute,  unfettered  by  any  previous  regulations,  and  free 
from  interference  on  the  part  of  the  hospital  autfiorities. 
5«:M. — Encourage  the  publication  in  different  coun- 
tries of  cook-books  for  the  sick.     These  books  should  be 


in  accord  with  the  dietary  customs  of  the  countries  in 
which  they  are  published,  and  should  indicate  the  pro- 
portions of  albuminoid  substances,  fats,  and  hydrocar- 
bons contained  in  the  various  dishes,  in  the  same  way  as 
the  doses  of  medicinal  substances  are  indicated  in  the 
pharmacopoeias. 

Seventh, — Every  physician  should  have  suspended  on 
the  wall  of  his  office  a  chart,  after  the  model  of  Konig's, 
showing  the  quantitative  composition  of  the  ordinary 
aliments.  In  this  way  the  importance  of  a  rationed 
dietetic  regime  would  be  constantly  before  his  mind,  and 
the  chart  would  aid  him  in  his  dietetic  prescriptions. 

Eighth, — Those  who  make  a  study  of  popular  hygiene, 
and  who  are  able  to  do  so,  should  occupy  themselves 
with  the  preparation  and  rational  composition  of  a 
dietary,  which  shall  be  sufficient  and  as  cheap  as  possible 
to  effect  an  amelioration  of  the  lot  of  the  poor. 

Finally,  the  author  said  that  he  would  be  pleased  to  see 
the  formation  of  an  international  association,  composed 
of  physicians  of  different  countries,  with  the  aim  of  ap- 
plying the  facts  of  alimentary  physiology  to  the  practice 
of  medicine  and  to  hygiene.  The  association  would  at 
the  same  time  be  subservient  to  the  interests  of  science. 


ON  SOME  DISORDERS  OF  NUTRITION  RE- 
LATED WITH  AFFECTIONS  OF  THE  NER- 
VOUS SYSTEM. 

Being  the  Address  in  Medicine  Delivered  Before 
THE  Brftish  Medical  Association  at  its  Meeting 
IN  Belfast,  Ireland,  July  30,  1884. 

By  WILLIAM  M.  ORD,  M.D.,  F.R.C.P., 

PHYSICIAN  TO  ST.  THOMAS's  HOSPITAL,  LONDON,  BNGLAMD. 

KSpedal  ibr  Thb  Mkdical  Rbcobek) 

Subjects  of  discourse  are  assuredly  not  lacking  when 
an  address  in  medicine  is  to  be  delivered.  To  me,  think- 
ing of  many — ^for  example,  of  subjects  historical,  of  sub- 
jects ethical,  of  subjects  polemical — has  come  the  final 
selection  of  a  subject  which,  appertaining  as  yet  very 
little  to  any  one  of  these  categories,  has  for  some  years 
very  largely  occupied  my  thoughts.  A  few  minutes 
after  I  received  the  honor  of  being  invited  by  your  Pre- 
sident to  deliver  this  address,  I  happened  to  meet  a 
friend  whose  advice  I  value  very  much.  He  at  once 
suggested  that  I  should  talk  about  some  subject  to  which 
my  thoughts  had  been  much  directed,  and  specified  cer- 
tain disorders  of  nutrition  related  with  affections  of  the 
nervous  system  which  had  certainly  interested  me  very 
deeply,  and  were  capable  of  general  discussion.  I  took 
the  advice,  and  set  to  work  to  write  the  paper.  Pre- 
sently I  found  that  one  subject  with  which  I  proposed  to 
deal,  the  subject  of  chronic  arthritis,  was  to  be  handled 
in  the  Section  of  Medicine  by  my  able  friend  and  col- 
league in  the  last  International  Medical  Congress,  Dr. 
Dyce  Duckworth,  and  that  the  influence  of  nervous  sys- 
tem on  norma]  and  abnormal  nutrition  was  to  be  intro- 
duced in  the  Section  of  Physiology  and  Pathology,  by 
Dr.  Alexander.  On  reflection,  I  decided  not  to  alter 
my  intention.  The  fact  that  the  subject  which  I  had 
chosen  was  also  in  the  thoughts  of  others  promised  me  a 
critical  audience ;  and  in  the  multiplying  of  observations, 
probably  all  regarding  the  question  from  different  stand- 
points, there  was  offered,  so  far,  greater  probability  of 
apprehending  the  truth. 

Let  me  invite  you,  then,  to  follow  me  in  considering 
some  perversions  of  nutrition  of  the  body,  or  its  parts, 
brought  about,  or  appearing  to  be  brought  about,  by  the 
morbid  agency  of  the  nervous  system. 

I  will  ask  you  to  let  me  put  a  sort  of  label  on  the 
matters  of  discourse,  and  to  speak  of  them  as  Neurotic 
Dystrophies.  They  will  include  conditions  of  overnu- 
trition,  and  of  undernutrition,  where  the  variation  is  of 
quantity  rather  than  of  kind ;  conditions  of  misdirected 
or  eccentric  nutrition,  where  the  variation  is  of  kind  as 
well  as  of  quantity. 


204 


THE  MEDICAL  RECORD. 


[August  23,  1884. 


The  little  used,  or  scarcely  recognized  term,  dystro- 
phy, will  for  my  purpose  cover  these  various  perver- 
sions, and  the  adjective  neurotic  will  indicate  the  aspect 
from  which  I  wish  for  the  moment  to  regard  them.  They 
will  not  be  exclusively  dealt  with.  This  is  inconsistent 
with  the  limits  of  an  address.  I  shall  only  discuss  some 
three  or  four  instances,  and  discussing  those  shall  rather 
review  than  attempt  to  prove.  The  general  direction  of 
my  thoughts  in  relation  to  this  subject  may  be  best  illus- 
trated by  certain  neurotic  dystrophies  of  joints  and  mus- 
cles. 

Muscular  atrophy^  produced  by  joint-lesions, — M.  Char- 
cot, in  last  year's  Progris  Medical^  has  treated,  with  that 
marvellous  lucidity  which  belongs  to  him,  of  certain  ef- 
fects upon  the  nutrition  and  contracture  of  muscles,  de- 
termined to  all  appearance  by  aflfections  of  joints.  That 
the  nutrition  of  the  muscles  of  limbs  in  which  the  joints 
are  affected  by  chronic  and  painful  disease  is  often  sub- 
ject to  impairment,  has,  as  M.  Charcot  in  his  paper  in- 
dicates, been  long  ago  observed  But  M.  Charcot's 
method  of  treatment  of  the  correlation  gives  to  it  a  new 
etiological  aspect.     Let  me  quote  two  of  his  cases. 

A  man,  aged  twenty-three,  in  the  telegraph  service, 
having  been  previously  healthy  in  all  respects,  had,  about 
a  year  previous  to  examination,  struck  his  right  knee  in 
jumping  over  a  fallen  tree.  It  is  important  to  notice 
that  the  injury  at  the  time  did  not  appear  to  be  severe, 
and  that  he  walked  afterward  several  miles  without  diffi- 
culty. At  length  he  stopped  for  a  time,  and  then  found 
himself  unable  to  walk  without  a  stick.  For  a  week 
afterward  he  kept  his  bed ;  the  joint  was  swollen,  but  not 
very  painful,  but  there  was  a  remarkable  loss  of  motor 
power  in  the  limb. 

At  the  time  of  M.  Charcot's  lecture  on  the  case,  the 
patient  presented  a  weakness  of  the  extensors  of  the  legs, 
almost  amounting  to  paralysis,  associated  with  some  loss 
of  power  and  wasting  of  the  rest  of  the  muscles  of  the 
limb.  While  the  whole  limb  was  smaller  in  volume  than 
the  opposite  limb,  it  was  obvious  that  the  anterior  aspect 
of  the  thigh  was  most  affected ;  the  muscles  of  that  re- 
gion were  limp,  and  presented  no  projection  even  at  the 
moment  of  exertion. 

Two  things  were  then  evident  \  paresis  of  the  muscles 
of  the  limb,  generally  most  marked  in  th/e  triceps  \  a 
wasting  of  the  muscles  of  the  limb  generally',  again  most 
marked  in  the  triceps.  Tested  by  electricity,  the  mus- 
cles and  their  nerves  gave  so  little  reaction,  both  to  gal- 
vanic and  faradic  currents,  that,  to  use  Af.  Charcot's  ex- 
pression, one  would  have  thought  that  the  muscles  were 
absent.  There  was  a  simple  quantitative  modification 
of  both  reactions,  giving  rise  to  the  conclusion  that  the 
condition  was  one  of  simple  atrophy,  and  not  of  a  degen- 
erative atrophy,  with  which  the  well-known  "  reaction  of 
degeneration "  would  have  been  associated.  To  these 
tests  M.  Charcot  added  a  third,  namely,  the  application 
of  the  electric  spark.  He  placed  the  patient  on  an  in- 
sulated table,  and  connected  him  with  a  frictional  elec- 
tricity machine.  A  spark  being  drawn  from  the  front  of 
the  thigh,  or  from  the  region  of  the  vastus  internus,  an 
energetic  contraction  of  muscles  followed.  Percussion 
of  the  right  triceps  produced  an  evident  contraction,  and 
percussion  of  the  patellar  tendon  determined  marked 
shocks,  not  only  on  the  side  of  the  percussion,  but  also  in 
the  two  upper  limbs,  particularly  in  the  left.  There  was 
no  ankle-clonus.  The  muscles  of  the  front  of  the  right 
leg  and  calf  contracted  less  forcibly  under  electrical 
stimulation  than  the  muscles  of  the  opposite  side.  M. 
Charcot  states  that,  at  the  time  of  his  demonstration, 
much  of  the  loss  of  power  had  already  disappeared  under 
the  steady  use  of  electrical  stimulation.  Discussing  the 
bearings  of  the  case  with  the  most  delicate  refinement  of 
analysis,  M.  Charcot  grasps  at  once  the  fact  tliat  the 
wasting  and  loss  of  power  exhibited  by  the  muscles  was 
out  of  all  proportion  to  the  severity  of  the  injury  and  the 
amount  of  suffering.  He  dismisses  theories  of  propaga- 
tion of  articular  inflammation  to  the  neighboring  muscles. 


He  dismisses  the  theory^  of  atrophy  from  prolonged 
inertia,  and  finds  himself  reduced  to  admit  the  existence 
of  what  he  calls  a  deuteropathic  spinal  affection,  giving 
rise  to  the  paralysis  and  the  atrophy.  In  the  absence  of 
the  "  reaction  of  degeneration,"  he  finds  himself  unable 
to  recognize  any  indication  of  a  serious  change  in  the 
anterior  horns  of  the  gray  matter  of  the  spinal  cord,  and 
is  reduced  to  the  suggestion  of  a  kind  of  stupor  or  inertia 
of  the  nerve-cells.  He  is  also  reduced  to  the  explanation 
of  the  exalted  tendon-reflexes  by  the  hypothesis  that, 
while  the  cells  of  the  affected  region  are  in  a  state  of  tor- 
por, there  is  a  condition  of  exaggerated  reflex  excitability 
in  the  rest  of  the  spinal  cord. 

The  second  case  is  that  of  a  hair-dresser  aged  fifty-one. 
Here  a  chronic  rheumatoid  arthritis  had  affected  the 
wrists,  the  shoulders,  the  ankles,  the  knees,  the  hips,  the 
elbows,  the  fingers  to  a  slight  dei^ree,  and  the  cervical 
articulations  in  succession.  There  was  neither  pronounced 
inflammation  nor  pain  ;  but  there  followed  a  rapid  wast- 
ing and  a  great  loss  of  muscular  power.  The  wasting  of 
muscles  was  unequal,  falling  chiefly  in  the  extensors  of 
the  limbs.  These  showed  the  same  loss  of  sensibility  to 
electrical  stimulation  which  had  been  observed  in  the 
other  case,  with  one  exception  :  the  right  vastus  extemus 
presented  the  reaction  of  degeneration.  Many  of  the 
atrophied  muscles  were  the  seat  of  fibrillar  contractions. 
Some  of  them,  the  left  deltoid  in  particular,  were  excita- 
ble  by  simple  percussion.  The  loss  of  power  was  in  ex- 
cess of  the  wasting.  The  tendon-reflexes  were  again 
strongly  accentuated  To  the  conditions  here  enumer- 
ated M.  Charcot  adds,  from  observation  of  other  cases, 
"contracture,"  tonic  contraction  of  certain  muscles, 
chiefly  of  flexors. 

Summing  up  these  and  other  cases,  M.  Charcot  argues 
that  the  paresis,  wastings  of  certain  muscles,  contractures 
of  certain  muscles,  and  the  other  associated  symptoms,  in- 
dicate an  influence  propagated  from  the  affected  joint  or 
joints,  incident  on  the  spinal  cord,  and  thence  reflected 
to  the  muscles,  giving  rise  in  the  one  set  of  cases  to  con- 
tracture, where  exaltation  of  function  must  be  supposed 
in  another  set  of  cases  to  atrophy,  where  depression  of 
function  must  be  supposed. 

If  we  accept  M.  Charcot's  conclusions,  we  have  in  this 
CTOup  of  cases  a  dystrophy  of  muscles,  brought  about  by 
irritation  commencing  in  joints  more  or  less  related  with 
those  muscles,  propagated  through  centripetal  nerves  to 
the  spinal  cord,  and  reflected  thence  by  centrifugal  nerves 
to  the  muscles. 

M.  P.  Berger  has  related  for  us  some  cases  presenting 
the  converse  of  the  observations  of  M.  Charcot  just  re- 
lated. In  M.  Berger's  cases,  fracture  of  the  upper  part 
of  the  femur  near  the  hip-joint  was  followed  by  arthritis 
of  the  knee ;  not  attributable  in  any  way  to  extension  of 
inflammation  through  the  intermediate  tissues.  M.  Ber- 
ger's  observations  would  lead  to  the  establishment  of  the 
possibility  of  a  reflex  influence  reversing  the  path  of  the 
influence  just  quoted.  In  other  words,  we  have  before 
us  observations  suggesting  that  joints  being  inflamed  may, 
bjr  a  reflex  influence,  give  rise  to  dystrophies  of  asso- 
ciated muscles ;  and  that  bones  and  surrounding  textures 
being  injured  may  give  rise  to  dystrophies  of  neighboring 
joints.  Such  considerations  carry  us  on  to  search  for 
the  middle  term ;  to  examine  if  there  be  any  evidence 
indicating  a  direct  morbid  influence  of  the  spinal  cord  on 
the  nutrition  of  the  component  parts  of  limbs  in  com- 
mon ;  and  secondly,  they  may  lead  us  to  inquire  whether 
the  nutrition  of  joints  and  other  parts  of  limbs  may  be  a£. 
fected  by  influences  propagated  from  viscera ;  that  is  to 
say  from  parts  which  are  not  components  of  limbs. 

Chronic  rheumatic  or  rheumatoid  arthritis  as  work 
of  nerve-influence. — Having  this  in  view,  I  will  ask  you 
to  accompany  me  in  considering  chronic  rheumatic  ar- 
thritis as  a  possible  work  of  nerve-influence.  I  use  this 
term,  chronic  rheumatic  arthritis,  because  I  am  speaking 
in  Ireland  in  the  presence  of  many  men  who  must  be 
well  acquainted  with   the  work  of  Adams,  of  Dublin. 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


205 


Chronic  rheumatic  arthritis  is,  as  you  will  also  know,  but 
one  of  many  names  given  to  an  affection  of  joints,  sp6ken 
(J  by  the  non-medical  public  as  rheumatic  gout.  The 
ooifoid  lesions  of  this  disease  are  of  a  kind  justifying  com- 
pletely the  application  to  them  of  the  term  dystrophy; 
for  i^e  they  include  destructive  inflammation  of  articu- 
lar cartilages,  and  subsequently  of  the  bone  beneath,  they 
indade  also  hypertrophic  changes  in  the  S3movial  mem- 
brane, and  in  the  periosteum  around  the  articular  sur- 
ftces. 
Here,  once  more,  I  must  refer  to  the  work  of  M. 

I  Charcot  whose  name  is  associated  with  the  remarkable 
observation  that  a  form  of  chronic  joint  disease,  present- 
log  both  the  atrophic  and  the  hypertrophic  lesions  of 
chronic  liieumatic  arthritis,  forms  a  part  of  the  phe- 
Qomena  of  tabes  dorsalis.  It  is  true  that  the  atrophy 
predominates  enormously;  but  the  hypertrophy  can 
always  be  recognized  by  any  one  who  may   care  to 

I  study  with  care  the  specimens  of  joint-trouble  exhibited 
by  M.  Charcot.  The  essential  lesion  of  tabes  dorsalis, 
as  at  present  recognized,  lies  in  the  spinal  cord,  and  is, 
so  £u,  a  central  nervous  lesion.  But  the  actual  seat,  yon 
will  remember,  is  not  in  the  gray  matter,  but  in  columns 
of  fibres,  which,  to  all  appearance,  are  the  channels  of 
centripetal  influence,  flowing,  at  least  in  part,  from  the 
Toluntary  muscles.  In  fact,  it  is  quite  possible  to  argue 
that  the  joint- lesion  may  be  here  the  result  of  reflection 
of  irritation,  propagated  to  the  gray  matter  of  the  spinal 
cotd  by  the  diseased  muscle-representing  fibres  of  the 
posterior  root-zone ;  that,  in  other  words,  muscles,  sub- 
jectively presented  to  the  gray  matter  as  in  a  state  of 
imtation,  can  induce  by  reflection  a  dystrophy  of  joints. 
If  there  be  any  possible  acceptance  of  the  idea  that 
joints,  being  irritated,  can,  by  reflex  trophic  influence, 
afiect  the  nutrition  of  muscles ;  and  that  muscles,  or 
their  centripetal  nerves,  being  irritated,  can  produce, 
also  by  reflex  trophic  influences,  dystrophies  of  joints,  we 
can  hardly  stop  ^ort  of  accepting  a  further  suggestion  to 
the  effect  that  some  part  of  the  central  nervous  system, 
presumably  some  part  in  the  spinal  cord,  presides,  in  a 
common  sense*  over  the  nutrition  of  organs  so  closely 
associated  as  joints  and  muscles,  perhaps  also  over  that  of 
bones. 

Turning  our  attention  to  what  is  known  of  the  direct 
infiuence  of  the  central  nervous  system  upon  the  nutri- 
tion of  muscles,  we  know  already  that  there  is  a  very  fair 
certainty  of  the  existence  of  a  definite  relation  between 
certain  affections  of  the  anterior  horns  of  the  gray  matter 
of  the  spinal  cord  and  atrophic  aflections  of  muscles. 

Associated  with  an  acute  inflammation  of  groups  of 
cells  in  the  anterior  horns,  are  found  the  phenomena  of 
inutile  and  essential  paralysis ;  associated  with  an  in- 
flammation of  the  same  anterior  horns,  diflering  from 
that  just  mentioned  in  being  chronic,  and  differing  prob- 
ably in  its  method,  are  found  the  phenomena  of  pro- 
gressive muscular  atrophy.  Infantile  paralysis  and 
progressive  muscular  atrophy  have  each  so  distinct  a 
grouping  of  symptoms  as  to  confer  on  each  a  marked 
clinical  identity,  and  on  each  an  assured  independence 
of  the  other.  Nevertheless,  they  have  in  common  one 
important  factor,  wasting  of  muscles  ;  but  the  wasting  of 
mnsdes  is,  if  we  may  judge  by  their  electrical  reactions, 
not  brought  about  by  the  same  process  in  the  two  cases. 
In  infantile  paralysis,  the  reaction  of  degeneration  leads 
us  to  infer  that  the  nutrition  of  muscular  (centrifugal) 
nerves  is  seriously  involved  In  progressive  muscular 
atrophy,  this  reaction  does  not  appear,  there  being  only 
a  diminution  of  electrical  reaction  proportionate  to  the 
loss  of  muscular  fibre. 

/cifU  lesion  in  progressive  muscular  atrophy. — My 
friend.  Dr.  Gulliver,  of  St  Thomas's  Hospital,  an  inheritor 
df  the  observing  faculty  and  accuracy  of  his  celebrated 
Either,  has  recently  communicated  to  me,  quite  indepen- 
doktly  of  this  address,  the  notes  of  a  case  in  which  a 
joint-lesion  appeared  as  a  part  of  the  phenomena  of  pro- 
gresave  musciUar  atrophy. 


In  studying  this  disease,  I  had  long  thought  that  there 
were  indications,  in  many  cases,  of  aflections  of  joints  as 
well  as  of  muscles.  Dr.  Gulliver  and  I  have  often  con- 
versed on  the  subject,  and  when  the  patient,  whose  case 
I  will  now  relate,  came  under  his  notice,  he  lost  no  time 
in  bringing  her  to  mine. 

K.  M ,  a  married  woman,  aged  fifty,  came  under 

treatment  in  June,  1884.  Of  the  family  history  nothing 
was  ascertained.  Her  previous  history  presented  noth- 
ing important,  save  that  she  had  never  had  rheumatism. 
For  six  or  seven  months  she  had  noticed  a  loss  of 
power  in  the  left  arm,  but  had  been  able  to  carry  on  her 
occupation  of  laundress  till  within  the  last  six  weeks. 
About  five  months  ago  she  began  to  experience  difiiculty 
in  speaking,  which  increased  till,  at  the  time  of  observa- 
tion, she  was  unable  to  articulate  in  any  intelligible  way. 
She  had  also  a  growing  difficulty:  in  swallowing,  with  im- 
pairment of  the  use  of  the  lips  m  movements  other  than 
diose  of  articulation,  for  instance,  in  blowing  out  a 
candle,  and  she  had  dribbling  of  saliva.  Three  months 
ago — at  least,  three  months  after  the  commencement  of 
muscular  feebleness — she  began  to  experience  pain  in 
the  left  shoulder-joint,  greatly  increased  by  raismg  the 
arm,  actively  or  passively.  At  the  time  of  observation, 
the  left  arm  was  found  to  be  much  wasted,  particularly 
in  the  forearm,  and  in  the  thenar  and  hypothenar  emi- 
nences. The  hand  had  the  claw- shape  characteristic  of 
progressive  muscular  atrophy  ;  it  was  the  main  en  griffe 
of  Duchenne  ;  and  she  could  not  oppose  the  tips  of  the 
fingers  to  the  tip  of  the  thumb.  She  could  not  raise  the 
left  arm  to  the  horizontal  position,  and  all  attempts  to  do 
so  gave  rise  to  much  pain  in  the  shoulder-joint.  All 
movement  involving  the  shoulder-joint,  whether  performed 
voluntarily  or  effected  by  other  persons,  gave  much  pain. 
The  joint  showed  no  coarse  changes ;  there  was  no 
affection  of  the  right  arm  or  of  the  legs  \  the  muscles  of 
both  arms  answered  equally  to  the  galvanic  current ;  those 
of  the  left  appeared  to  react  a  httle  readily  under  the 
faradic  ;  the  knee-jerk  was  more  active  than  usual  in  both 
legs.  The  tendon-reflexes  of  the  arms  were  investigated, 
but  the  results  were  not  definite.  She  could  not  speak, 
bein^  able  to  produce  nothing  more  than  a  monotonous 
inarticulate  sound ;  she  could  not  protrude  the  tongue, 
or  blow  out  the  lips.  The  palate  was  motionless  ;  and 
she  swallowed  with  difficulty. 

Although  the  order  of  affection  of  the  muscles  of  the 
arm  is  not  recorded,  the  case  is  clearly  one  of  progressive 
muscular  atrophy,  in  which  the  bulbar  affection  is  pre- 
dominant. And  while,  as  regards  the  limbs,  the  left 
upper  extremity  was  alone  affected,  the  painful  state  of 
the  left  humeral  articulation  indicates  the  existence  of  a 
definite  change  in  the  nutrition  of  a  joint  belonging  to 
the  same  area  of  innervation  as  that  of  the  sheeted 
muscles ;  and,  so  far  as  it  goes,  the  case  tends  to  show 
that  one  central  nervous  affection  may  give  rise  to  con- 
comitant dystrophy  of  joint  and  muscle. 

(To  bo  oontmued.) 


Treatment  of  Ununited  Fracture  of  the  Tibia. 
— Dr.  Eugene  Hahn  writes,  in  the  Centralblatt  fUr  Chir- 
urgie  of  May  24,  1884,  describing  a  new  procedure  em- 
ployed by  him  with  success  in  the  treatment  of  pseudar- 
throsis  of  the  tibia.  The  case  was  one  of  compound 
comminuted  fracture,  in  which  there  had  been  a  loss  of 
a  considerable  amount  of  bone-substance,  the  two  ends 
of  the  tibia  being  separated  about  three  Inches.  Various 
attempts  had  been  made  to  secure  union  without  success, 
until  it  occurred  to  Dr.  Hahn  to  implant  the  broken  end 
of  the  fibula,  which  bone  had  been  fractured  higher  up 
than  the  tibia  into  the  medullary  canal  of  the  upper 
fragment  of  the  ribia.  He  did  so,  and  union  took  place 
between  the  two  bones  with  the  result  of  restoring  the 
usefulness  of  the  limb.  The  patient  wore  a  light  reten- 
tion splint  on  the  leg,  and  was  able  to  walk  about  with 
ease. 


206 


THE  MEDICAL  RECORD. 


[August  23,  1884. 


The  Medical  Record: 


A  Weekly  youmal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Lafayette  Place. 

New  York,  August  33,  Z884. 

THE  RESCUE  OF  LIEUTENANT  GREELY, 
THE  EFFECTS  OF  THE  ARCTIC  CLIMATE, 
AND  THE  QUESTION   OF   CANNIBALISM. 

Thb  Arctic  regions  have,  by  the  enterprise  and  heroism 
of  Commander  Schley,  been  compelled  to  surrender  the 
living  remnants  of  Greel/s  party,  and  some  of  the 
dead  bodies  of  victims  of  this  unfortunate  expedition. 
The  fisu:ts  of  the  fitting  out  of  this  expedition  in  the  in- 
terest of  science,  the  lamentable  failure  of  our  Navy  De- 
partment last  year,  and  the  year  before,  to  place  supplies 
where  they  were  the  most  needed,  and  the  terrible  chap- 
ter of  su£fering  and  privation  which  succeeded  the  re> 
treat  of  the  party  in  August,  1883,  from  Lady  Franklin 
Bay  to  Cape  Sabine,  and  their  long  incarceration  in  the 
latter  locality — a  chapter  of  desolation  and  misery  of 
which  the  half  has  not  yet  been  told — are  sufficiently  far 
miliar  to  the  readers  of  The  Record. 

If  it  should  be  proved  that  the  necessity  of  cannibal- 
ism was  added  to  the  horrors  of  the  last  year's  expe- 
riences of  this  party,  the  story  of  hardship  and  wretched- 
ness would  seem  to  be  about  as  black  as  reality  could 
make  it,  or  even  imagination  could  paint  it. 

A  private  interview  with  Lieutenant  Greely,  at  his  for- 
mer home,  has  enabled  us  to  obtain  a  somewhat  clearer 
insight  into  the  physiological  and  pathological  effects 
of  prolonged  residence  in  the  Polar  regions,  as  well  as 
the  straits  to  which  the  Greely  party  were  finally  re- 
duced. He  ascertained  that  such  sojourn,  by  inhabitants 
of  warmer  climates  who  are  in  good  physical  trim,  is  for 
a  brief  term  of  years  compatible  with  a  high  state  of  all 
the  organic  functions,  in  which  there  is  entire  freedom 
from  diseased  manifestations  of  every  kind ;  but  there  is 
a  decided  limit  to  the  endurance  by  Europeans  and 
Americans  of  such  extreme  prolonged  cold.  The  system 
is  at  first,  and  for  a  long  time,  by  an  admirable  series  of 
internal  adjustments,  braced  up  against  the  rigors  of  cli- 
mate ;  but  after  the  first  year  a  considerable  deterioration 
in  muscular  and  nervous  energy,  and  in  the  calorigenous 
processes  of  the  economy  is  experienced.  The  severity 
of  the  second  winter  was  found  by  the  party  somewhat 
harder  to  bear,  but  the  experience  of  the  previous  win- 
ter had  taught  them  how  best  to  fortify  and  protect  them- 
selves, and  husband  their  forces.  The  third  long  Arctic 
night,  in  which  the  thermometer  was  never  less  than  three 
below  zero,  and  much  of  the  time  was  down  to  forty  or 
fifty  below,  would,  under  the  most  favorable  circumstan- 
ces, have  been  a  painfiil  season  to  the  party ;  vital  reac- 


tion jfz&  quite  perceptibly  lessened ;  muscular  tone  was 
impaired,  rendering  exertion  difficult,  and  rheumatisms 
began  to  prevail.  Could  the  party,  however,  have  had 
plenty  of  food,  and  full  and  good  shelter,  they  would  un. 
doubtedly  have  all  been  living  at  this  day.  Lieutenant 
Greely,  in  reply  to  an  interrogatory,  affirmed  his  doubts 
as  to  whether  his  men,  if  well  provisioned,  could  have 
continued  to  live  at  Fort  Conger  more  than  five  yean. 
The  constitution  of  the  average  American  is  not  capable 
of  prolonged  continuous  adjustment  to  more  than  zero 
cold,  and  such  acclimatization  could  only  come  about 
after  a  series  of  generations  where  the  law  of  sunrival  of 
the  fittest  should  operate,  and  in  correspondence  with  a 
radical  change  in  organization,  in  which  nutritive  and 
muscular  development  should  predominate  over  cerebral 
development ;  in  other  words,  nature  has  shown  us  in 
the  mentally  dwarfed  but  physically  hardy  Esquimaux, 
the  type  of  organization  best  fitted  for  living  in  those  sep 
tentrional  latitudes.  It,  however,  is  no  less  a  matter  of 
fact  that  the  inhabitants  of  meridional  climes  admirably 
adapt  themselves  temporarily  to  the  most  extreme  cold. 
In  the  retreat  fi-om  Moscow,  in  1812,  the  Italian  regi- 
ments stood  the  cold  better  than  the  Germans,  and  notap 
bly  better  than  the  Russians,  who  were  accustomed  to 
the  climate."  The  Turks  presented  the  same  relative 
immunity  at  the  siege  of  SebastopoL  Longet,  from 
whom  these  £u:t8  are  taken,  remarks  that  the  aptitude  to 
resist  inclement  temperature  is  acquired  and  lost  in  torn; 
that  people  nurtured  in  temperate  or  cold  climatesi  who 
go  to  the  torrid  zone  to  live,  are  much  less  sensitive  to 
the  cold  for  a  time  after  their  return  to  their  native 
country,  though  this  lessened  susceptibility  disappears 
after  a  year  or  two. 

As  man  can  live  amid  intense  surrounding  cold  only 
by  keeping  his  internal  temperature  at  about  98^^  F.,  all 
the  calorigenous  centres — ^which  comprise  every  living 
element  or  cell  in  every  part  of  the  body — are  stimulated 
to  greatly  augmented  activity ;  the  respiratory,  digestive, 
and  assimilative  processes  are  performed  with  unwonted 
energy ;  the  heart's  action  and  the  circulation  are  nota- 
bly quickened.  Lieutenant  Greely  remarked  that 
breathing  air  of  such  intense  coldness  had  something  of 
the  efifect  produced  by  breathing  pure  oxygen  ;  as  for 
pulmonary  troubles  he  heard  no  complaint  of  them  while 
the  party  was  at  Fort  Conger,  in  Lady  Franklin  Bay,  at 
a  latitude  of  about  83^,  where  the  first  two  years  were 
spent;  even  simple  catarrhs  were  unknown,  the  only  | 
thing  from  which  the  men  suffered  being  occasional  rheu- 
matisms, and  stiffness  of  the  muscles  and  joints. 

The  party  had  ferocious  j^petites  during  all  of  this 
long  sojourn  in  the  North,  each  man  eating  with  relish 
three  meals  of  animal  food  and  two  lunches  every  day, 
and  craving  fats,  though  not  to  the  extent  which  some 
Arctic  travellers  report.  Not  even  when  the  thermo- 
meter marked  60^  below  zero  did  these  men  indulge  in 
crude  blubber  or  tallow  candles^  which  tradition  has  des- 
ignated as  the  customary  food  of  Arctic  voyagers ;  nor 
was  even  pemmican  regarded  as  a  rare  and  dainty  dish 
by  them.  Canned  meats,  of  which  they  had  an  abuDd- 
ance  during  the  first  two  years,  and  a  steak  or  ragout 
from  the  walrus,  seal,  or  polar  bear,  were  prized  as  the 


'  Longet :  Trait^  de  Phys.,  t  iL,  page  54a 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


207 


essentia]  conditions  of  well-being.  As  for  spirituous  li- 
qaorsy  tiiej  were  used  with  great  moderation  and  doled 
oat  to  the  members  of  the  expedition  as  occasion 
seemed  to  demand,  and  only  when  some  unusual  exer- 
tion or  exposure  brou^t  extraordinary  £eitigue  or  pros- 
tration ;  as  means  to  fortify  the  sy§ktm  against  cold  or 
brace  it  up  for  forced  marches,  whiskey,  rum,  and  other 
alcoholic  stimulants  were  regarded  as  of  little  benefit. 

The  party  slept  well  during  all  their  long  stay  at  the 
North,  except  during  the  last  few  months  of  physiological 
misery,  when  the  pangs  of  hunger  and  the  weakened, 
disordered  condition  of  their  anaemic  brains  precluded  re* 
freshing  sleep  ;  in  the  case  of  some  of  them  the  horrors 
of  scurvy  made  their  state  more  deplorable  still. 

As  for  the  prolonged  agony  at  Cape  Sabine,  sympa- 
thizing, pitying  humanity  would  fain  draw  a  veil  over 
those  appalling  scenes  which  can  be  imagined,  but  can- 
not be  described.  If  men  driven  to  madness  by  long 
fasting,  the  only  means  of  sustenance  available  being 
strips  of  seal-skin,  shrimps,  and  Arctic  moss,  their  scanty 
rations  being  exhausted;  entertaining  the  forlorn  hope 
that  if  they  might  hold  out  only  a  few  weeks  longer  de- 
hrerance  would  come  to  them ;  if  under  such  circum* 
stances  there  were  no  alternative  but  death  or  anthropo- 
phagy, it  may  seem  to  us  that  death  would  be  prefer* 
able  to  life  sustained  on  such  terms^  but  we  can  realize 
neither  the  hunger,  nor  the  desperation,  nor  even  the  im- 
pelling strength  of  the  most  imperious  instinct  of  our  na- 
ture. 

In  justice  to  Lieutenant  Greely,  it  must  here  be 
stated  that  he  denies  all  km>wledge  of  cannibalism  as 
having  been  practised  by  any  members  of  his  party.  If 
some  of  the  men,  to  save  their  lives,  fed  on  the  carcasses 
of  their  companions,  it  is  a  matter  for  which  they  are  in- 
dividually responsible,  not  he. 

The  results  of  the  autopsy  of  Lieutenant  Kislingbury 
are  quite  significamt.  We  make  no  comment  on  the  sworn 
statement  of  the  physicians,  except  to  call  attention  to 
the  fact  that  the  body  was  stripped  of  muscle  where  the 
masde  was  the  thickest ;  the  pectoral,  gluteal,  dorsal  re- 
gions, the  thighs,  legs,  and  arms  in  their  entirety,  were 
denuded  of  flesh,  and  there  was  evidence  that  this  was 
done  with  a  knife  ;  not  that  the  soft  parts  were  gnawed 
away  by  some  wild  animal ;  moreover,  the  viscera  were 
intact.  Virtually  the  same  thing  was  done  with  the  body 
of  Private  Whistler,  as  also  proved  by  post-mortem  ex- 
amination. 

There  is,  we  hardly  need  say,  other  evidence,  obtained 
from  members  of  the  rescuing  crew,  that  goes  to  estab- 
lish the  fact  of  cannibalism  at  Cape  Sabine.  It  is  proper 
to  say,  however,  that  the  results  of  the  examination  of 
the  contents  of  the  Kislingbury  stomach  cannot,  by 
themselves  (^ove  absolutely  that  human  flesh  was  eaten. 
Ul  this  connection  we  would  refer  to  the  letter  of  Dr. 
Heineman  (see  page  2 16),  in  which  some  very  sugges- 
ti?e  questions  are  asked. 

In  considering  this  revolting  subject,  it  is  the  scientific 
or  physiological  side  that  claims  our  attention.  Can  the 
practice  of  camnibalism  by  civilifed  men — men  of  natu- 
rally human  and  refined  natures — ^be  conceived  as  fossibU 
ander  any  circumstances?  What  are  the  psychological 
antecedents  and  accompaniments  of  anthropophagy? 
Is  cannibalism  ever  justifiable,  and  was  it  justifiable  in 


the  Greely  party,  in  the  straits  to  which  they  were  re- 
duced ?  In  other  words,  what  is  the  moral  aspect  of  the 
question  ? 

I.  Can  the  pnu:tice  of  cannibalism,  by  civilized  men, 
be  conceived  as  possible  ?  It  is  true  that  no  one  of  the 
readers  of  this  journal  can  easily  imagine  the  affirmative 
of  this  question  in  its  application  to  himself;  looking  at 
it,  ais  he  must,  from  the  high  normal  plane  to  which, 
through  ancestral  inheritance  and  moral  culture,  count- 
less evolutionary  ages  have  raised  him.  And  doubtless, 
the  average  civilized  man  could  not  be  brought  to  an  act 
of  cannibalism  by  any  process  of  acute  starvation.  Lord 
Ross  has  remarked  that  even  the  savage  Esquimaux  will 
starve  rather  than  eat  human  flesh. 

But  here  we  must  emphasize  the  work  acute^  as  op- 
posed to  chronic  starvation.  Not  one  week  or  two  can 
easily  undo  the  work  of  ages,  as  manifested  in  the  de- 
velopment of  brain,  and  the  noblest  powers  of  mind. 
Amid  the  general  languishment  of  the  organs  and  tis- 
sues, the  brain  and  nervous  system  the  longest  maintains 
its  integrity.*  There  is  prostration,  there  is  hebetude  of 
the  nervous  functions,  but  delirium  comes  late,  if  at  all, 
and  when  it  makes  its  appearance,  the  unhappy  sufferer 
is  too  feeble  to  make  any  energetic  effort  to  save  him- 
self. 

But  it  is  not  so  in  chronic  starvation,  that  may  be 
many  weeks,  if  not  months,  in  efiecting  the  deteriora- 
tion and  destruction  of  the  organism.  In  all  ages,  and 
among  all  nations,  there  have  been  histories  of  famine 
in  connection  with  sieges,  droughts,  etc.,  where  pro- 
longed inanition  has  driven  men  to  cannibalism.  Such 
facts  show  that  anthropophagy  has  been  possible  under 
circumstances  of  deepest  misery ;  and  thb  brings  us  to 
the  second  question :  What  are  the  psychological  accom- 
paniments of  cannibalism  ?  Under  this  head  we  must  be 
brief.  There  is  no  doubt  that  the  functional  integrity  of 
the  brain  and  mind  is  dependent  on  sufficiency  of  good 
food  and  a  healthy  nutrition.  He  that  enjoys  most  the 
cerebral  acquisitions  which  he  has  inherited  and  culti- 
vated, is  the  man  who,  ccUeris  paribus^  is  the  best  nour- 
ished. Conversely,  long  continued  mal-nutrition  effects 
what  Hughlings- Jackson  calls  gradual  dissolution  in  the 
'<  topmost  layers  "  of  the  highest  centres  ;  the  individual 
is  now  "lost  to  his  surroundings,''  is  "defectively  con- 
scious." In  other  words,  the  victim  of  chronic  inanition 
becomes  a  degraded  being,  and  is  capable  of  lapsing  into 
a  stage  where  brute  instincts  and  brute  appetites  pre- 
dominate. 

In  the  famine  which  attends  on  long  sieges,  mothers 
have  been  known  to  devour  their  own  offspring,  whose 
lives  they  had  taken.  "  Verily,"  as  Longet  observes, 
"  where  the  maternal  instinct  perishes,  every  other  no- 
blest instinct  must  have  departed." 

The  psychological  antecedent  and  accompaniment  of 
cannibalism,  then,  is  a  state  of  positive  frenzy  or  insanity, 
from  which  every  element  of  moral  responsibility  is  lack- 
ing. The  words  "  delirium  of  famine  "  appropriately 
designate  this  condition,  and  are  so  used  by  some  authors. 

To  apply  this  thought  to  the  particular  case  under  con- 
sideration, who  will  say  that  the  life  at  Cape  Sabine  did 
not  present  all  the  conditions  requisite  for  engendering 

*  According  to  Chossat's  experiment,  the  nervous  system  scarcely  loses  1.9  per 
cent,  of  its  substance.    Recherdies  Exp^rimentales  sur  I'lnanidon.    Paris,  1843. 


208 


THE  MEDICAL  RECORD. 


[August  23.  1884. 


in  some,  if  not  in  all  the  members  of  the  party,  the  nec- 
essary psychical  and  physiological  antecedents  of  canni- 
balism? It  seems  more  probable,  however,  that  the 
eating  of  human  fiesh  was  comparatively  a  late  occur- 
rence in  the  dreadful  experience  at  Cape  Sabine ;  this 
means  of  sustaining  life  not  being  resorted  to  till  their 
regular  rations  were  almost  if  not  quite  consumed.  It 
will  be  remembered  that  Kislingbury  died  virtually  of 
starvation,  and  that  in  his  stomach  there  was  not  a  vestige 
of  animal  or  human  fiesh. 

3.  Is  cannibalism  ever  justifiable  ?  1  Was  it  justifiable 
at  Cape  Sabine  ?  Every  right-minded  person  will,  we 
think,  say  "  Yes  !  **  If  the  question  of  irresponsibility  is 
settled  in  the  affirmative,  then  all  discussion  of  the  moral 
aspect  of  cannibalism  is  foreclosed — there  can  be  no  im- 
morality in  the  case.  If  any  or  all  of  this  band  of  devoted 
heroes,  who  so  barely  escaped  being  martyrs  to  science, 
were  saved  by  eating  the  dead  bodies  of  their  comrades, 
with  a  deliberate  suppression  of  an  irrational  sentimen- 
tality, and  not  without  due  reverence  for  the  dead,  we 
say  that  we  regard  the  act  under  the  circumstances  as 
justifiable.  We  believe  that  no  pretence  has  ever  been 
made  that  these  men  murdered  any  of  their  companions 
for  such  a  purpose. 

That  we  have  not  misrepresented  the  terrible  state  of 
mental  dilapidation  of  the  party  at  the  time  they  were 
found  is  apparent  from  all  the  testimony.  Lieutenant 
Powell  says  that  "  they  were  all  in  such  a  dazed  condi- 
tion that  they  did  not  realize  that  they  were  rescued 
until  they  had  been  given  some  ptarmigan,  and  then  they 
began  to  curse  the  rescuers  for  not  giving  them  more 
food." 

THE  PROPHYLAXIS  OF  MALARIA. 
The  address  on  malaria,  delivered  by  Professor  Tom- 
masi  Crudeli,  at  one  of  the  general  meetings  of  the  In- 
ternational Medical  Congress,  and  which  we  are  enabled, 
by  special  arrangements  made  in  Copenhagen,  and  by 
our  cable  facilities,  to  present  in  full  to  the  readers 
of  The  Record  this  week,  is  one  of  unusual  interest.  It 
deals  with  questions  of  vital  importance  to  humanity  and 
which  especially  concern  very  nearly  the  inhabitants  of 
our  own  land.  There  is  scarcely  a  township  in  the 
United  States  where  malaria  does  not  count  its  victims, 
and  in  many  portions  of  the  country  it  is  as  dreaded  a 
scourge  as  it  is  in  Italy  or  on  the  west  coast  of  Africa. 
Even  in  the  immediate  neighborhood  of  New  York 
pernicious  remittents  are  not  unknown,  and  deaths  from 
this  cause  figure  in  nearly  every  table  of  vital  statistics. 
It  is  on  account  of  the  interest  of  the  subject,  as  well  as 
because  of  the  deservedly  high  reputation  of  the  author, 
that  this  one  of  the  general  addresses  of  the  Congress  was 
selected  for  presentation  in  full  to  our  readers. 

The  author  is  strongly  opposed  to  the  paludal  theory 
of  malaria,  to  which,  indeed,  but  few  authorities  of  any 
weight  at  the  present  day  incline.  We,  at  least,  in  this 
country  need  no  array  of  arguments  to  disprove  the  no- 
tion that  the  malarial  ferment  is  formed  exclusively  in 
marshy  ground  and  is  thence  carried  by  the  wind  to 
other  dryer  and  more  elevated  regions.  An  ample  and 
a  sad  experience  has  taught  us  that  it  is  usually  indigen- 
ous to  the  soil  on  which  we  live,  and  that  no  exceptional 
degree  of  moisture  is  necessary  to  its  production. 


It  will,  perhaps,  be  a  matter  of  surprise  to  some  who 
remember  the  confident  predictions  made  a  few  years  ago 
of  the  extinction  of  malaria  by  the  cultivation  of  the  eu- 
calyptus-tree, and  who  have  not  noticed  the  growing  si. 
lence  of  those  who  were  formerly  most  enthusiastic  in 
their  advocacy  of  this  measure,  to  read  the  disparaging 
comments  of  the  author  upon  the  results  obtained.  The 
setting  out  of  eucaljrptus  plantations  is  attended  with  a 
great  expense,  which,  he  claims,  is  by  no  means  com- 
mensurate with  the  benefits  realized,  for  oftentimes  the 
good  efifects  are  purely  imaginary.  The  measures  which 
afford  the  greatest  hope  of  success  in  the  task  of  purify, 
ing  a  malarious  soil  consist,  in  the  author's  opinion,  in 
thorough  and  systematic  drainage  and  forced  cultivation 
of  the  ground.  Sowing  the  land  thickly  with  grass  offers 
a  barrier  to  the  escape  of  the  malarial  poison,  but  is  in 
the  nature  of  the  case  an  imperfect  method  of  securing 
immunity  firom  infection  ;  for  of  course  a  breach  is  made 
in  the  ramparts  every  time  that  a  spade  is  plunged  into 
the  sod,  and  the  enemy  is  never  slow  in  forcing  its  way 
through  the  broken  barriers. 

The  results  of  Professor  Crudeli's  experiments  in  the 
matter  of  individual  prophylaxis  are  those  which  offer  the 
most  encouragement.  This  is,  indeed,  the  first  difficulty 
to  be  surmounted ;  for,  as  he  rightly  says,  it  requires  time 
and  the  presence  of  man  in  order  to  repress  the  format 
tion  of  the  malarial  ferment,  and  unless  we  can  insure 
man  from  the  attacks  of  the  disease  during  this  prepara. 
tory  period,  the  reclamation  of  the  lands  can  never  be 
accomplished,  at  least  by  civilized  nations.  The  exces- 
sive use,  or  abuse  of  quinine,  like  the  abuse  of  mercury, 
is  nearly  as  balefiil  in  its  effects  as  the  disease  which  it  is 
designed  to  overcome,  hence  the  desideratum  that  exists 
for  some  prophylactic  remedy  that  is  at  once  a  real  pro- 
phylactic and  at  the  same  time  readily  obtainable  and 
suited  for  popular  use.  Arsenic,  which  the  experiments 
detailed  in  the  address  would  seem  to  show  does  possess 
prophylactic  virtues,  is  a  drug  that  could  hardly  be  put 
with  nfety  into  the  hands  of  the  laity,  despite  the  alleged 
existence  of  the  Styrian  toxiphagL  Whether  the  decoc^ 
tion  of  lemon  will  prove  on  more  extended  trial  to  pos- 
sess the  powers  that  are  claimed  for  it,  time  and  expe- 
rience  can  alone  determine.  The  author  shows  that  he 
is  endowed  with  the  true  scientific  spirit  in  being  ready  to 
examine  ihto  the  merits  of  a  popular  remedy  of  so  simple 
a  nature.  And  we  certainly  have  reason  to  hope  that 
such  conscientious  investigation  and  painstaking  research 
will  meet  with  their  reward.  The  sons  of  Italy  were  once 
foremost  in  the  ranks  of  science,  and  Crudeli  and  his  fel- 
low-laborers are  doing  much  to  restore  to  their  country 
her  proud  eminence  among  the  nations  of  the  earth. 


OUR  CABLED  REPORT  OF  THE  INTERNATIONAL  MEDI- 
CAL CONGRESS. 

We  are  happy  to  announce  the  completion  of  our 
cable  report  of  the  International  Medical  Congress  held 
in  Copenhagen.  The  most  notable  address  is  one  which 
we  have  the  pleasure  of  presenting  in  fiill — that  by  Pro£ 
Crudeli,  of  Rome.  Prof.  Panum's  address  is  given  io 
full  abstract,  while  the  remaining  proceedings  are  incor- 
porated in  the  general  cable  report,  including  the  ab- 
stracts of  addresses  by  Sir  William  Gull  and  Virchow. 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


209 


We  may  be  perhaps  excused  for  congratulating  our- 
selves on  such  a  successful  accomplishment  of  a  plan  for 
presenting  to  our  readers  on  this  side  of  the  Atlantic  a 
foil  and  authentic  report  of  one  of  the  most  notable  Con- 
gresses held  for  a  long  period.  We  have  been  enabled 
to  demonstrate  what  can  be  done  by  cable  by  giving 
an  accurate  report  of  the  doings  of  a  scientific  body  in 
which  subjects  of  a  purely  technical  character  are  dis- 


We  believe  we  have  succeeded  in  presenting  to  our 
readers  a  r/sum/  which  is  sufficiently  comprehensive  and 
isstractive  to  warrant  us  in  making  the  efifort*  The  ab- 
stracts of  addresses  and  papers  have  been  carefully  pre- 
pared by  our  correspondent  with  this  end  in  view,  and 
we  are  convinced  they  can  speak  for  themselves. 

As  will  be  seen,  the  meeting  was  a  success  from  every 
point  of  view — the  subjects  and  addresses  were  well 
selected)  and  the  different  orators  did  them  full  jus- 
tice, thus  giving  a  high  scientific  tone  to  the  meeting. 
Nor  were  the  sections  behindhand  as  to  subjects  of  in- 
terest or  of  speakers  to  present  them.  This  is  evident 
through  some  of  the  reports  which  we  give  of  sectional 
work. 

It  would  be  impossible,  of  course,  to  present  in  the 
time  allotted,  even  with  the  best  of  cable  facility,  an  ex- 
haustive report  of  the  proceedings,  but  sufficient  has  been 
done  to  give  our  readers  a  fair  idea  of  what  was  ac- 
complished by  the  Congress  as  a  whole.  Further  re- 
ports by  mail  will  give  fuller  detail.  The  social  element 
of  the  meeting  was  what  it  should  be,  and  though  gen- 
erous to  the  full  point  of  royal  hospitality  it  did  not 
interfere  in  any  manner  with  the  strictly  scientific  work. 
The  selection  of  the  next  place  of  meeting,  at  Washing- 
ton, D.  C,  was  good,  and  as  was  predicted  the  invitation 
on  behalf  of  the  profession  of  this  country  was  received 
with  a  becoming  cordiality.  It  remains  now  for  the 
profession  of  this  country,  by  every  means  in  its  power, 
to  make  the  next  session  of  the  Congress  a  success,  and 
demonstrate  in  due  form  its  appreciation  of  the  honor 
conferred  by  the  selection. 


CRUELTY  TO  THE  PAUPER  INSANE. 

Op  late  years  the  worst  accounts  regarding  thp  treatment 
of  the  insane,  in  the  East  and  North  at  least,  have  related 
to  the  pauper  insane  in  the  smaller  almshouses  and 
prisons.  The  last  story  of  cruelty  toward  this  class  comes 
from  Pennsylvania.  Dr.  Thomas  G.  Morton,  for  the  State 
Committee  on  Lunacy,  has  sent  the  following  letter  to 
every  physician  in  the  State  : 

Philadelphia,  August  16,  1884. 

My  Dear  Doctor  :  Two  instances  of  cruel  treatment 
of  msane  patients  in  charge  of  private  parties  have  re- 
cently come  to  the  knowledge  of  the  Committee  on 
Lunacy.  In  one  case  an  old  man  was  found  naked  in 
tn  outhouse  in  a  very  secluded  spot  of  the  State,  where 
he  had  been  confined  for  more  than  thirty  years  chained 
by  the  leg.  In  the  other  case  neither  the  public  nor  the 
Committee  had  any  knowledge  of  the  inhumanity  prac- 
tised upon  an  old  man,  who  had  likewise  been  chained 
for  more  than  a  quarter  of  a  century,  and  it  was  not 
until  his  death  that  the  particulars  were  brought  out  and 
made  public. 

In  view  of  these  facts,  the  object  of  the  committee  is 


to  find  out  if  any  such  cases  are  known  or  believed  to 
exist,  and  if  so,  to  send  them  to  the  State  hospitals  for 
the  insane,  where  they  can  receive  humane  and  proper 
treatment,  and  that  if  you  have  any  reason  to  believe 
any  such  insane  are  concealed  and  badly  treated,  we  will, 
on  private  information  from  you,  investigate  such  cases 
and  take  the  necessary  steps  for  their  transfer.  Any  com- 
munication will  be,  if  desired,  considered  confidential. 

Yours,  very  truly, 

Thomas  G.  Morton,  M.D. 

Since  the  publication  of  the  above,  another  case  of  a 
similar  character  has  been  published.  It  was  that  of  a 
young  man  who  had  been  confined  for  some  time  in  the 
Berks  County  Almshouse.  He  had  a  ball  of  heavy 
weight  chained  to  his  leg. 

The  facts  revealed  by  the  Pennsylvania  Committee 
teach  again  the  lesson  that  the  pauper  insane  ought  not 
to  be  kept  an3rwhere  except  in  institutions  provided 
especially  for  them,  and  under  responsible  medical  man- 
agement. Poverty  may  indeed  compel  counties  to  care 
for  some  of  their  own  insane  poor  in  workhouses.  But 
where  this  is  necessary  there  is  no  excuse  for  not  having 
carefiil  and  frequent  supervisions. 

Although  medical  philosophers  and  reformers  may 
reason,  demonstrate,  and  protest  they  very  well  know 
that  there  is  a  bad  political  method  at  the  bottom  of  most 
of  the  abuses  they  condemn.  The  people  must  be  edu- 
cated and  then  aroused  before  thorough  reform  can  take 
place. 

THE  CRIME  OF  A  MIDWIFE. 

The  Louisville  Medical  News  states  that  a  physician  in 
that  city  recently  returned  a  death  certificate  in  which 
the  cause  of  death  was  given  as  placenta  previa,  adding 
that  the  death  was  "superinduced  by  the  criminal  care- 
lessness of  a  midwife."  It  appears  that  the  deceased 
had  engaged  the  services  of  a  midwife.  She  had  suffered 
fi-om  hemorrhage  for  several  weeks  before  labor  came  on, 
but  the  midwife  paid  no  attention  to  it.  When  the  labor 
pains  began,  the  hemorrhage  was  very  profiise.  Still  the 
midwife  did  nothing,  except  leave  her  patient,  saying 
that  she  would  return  soon.  She  never  came  back  at 
all ;  and  the  patient  died. 

The  News  makes  the  above  the  text  for  a  very  vigor- 
ous attack  upon  the  midwife  in  general,  and  the  German 
midwife  in  particular.  As  for  remedies  the  editor  be- 
trays a  cynical  desire  to  see  all  midwives  poisoned  or  put 
out  of  the  way  by  some  means. 

The  suggestion  is  made,  however,  and  it  is  one  we 
cordially  endorse,  that  all  midwives  be  licensed,  and,  be- 
fore being  licensed,  be  obliged  to  give  evidence  of  some 
education  and  skill  At  present  the  chief  education 
which  the  midwife  receives  is  the  highly  subjective  one 
of  having  had  from  five  to  ten  babies  herself. 


An  Enthusiastic  Electro-therapeutist. — Accord- 
ing to  the  Medicinal  Central-Zeitung,  the  well-known  (?) 
therapeutist,  Dr.  Seimus,  has  gone  to  Marseilles  for  the 
purpose  of  setting  up  electric  machines  in  the  wards  of 
the  hospitals  there.  By  the  disengagement  of  ozone  he 
hopes  to  disinfect  the  air,  and  perhaps  assist  in  curing 
^he  patients. 


2IO 


THE  MEDICAL  RECORD. 


[August  23,  1884 


^ews  of  tttje  ySSizzU. 


Professor  L.  Hermann,  of  Zurich,  has  been  called 
to  the  chair  of  Physiology  at  Berlin  to  succeed  V.  Wittich. 

The  Celebrated  Physiologist,  Professor  Carl 
ViERORDTy  of  Tubingen,  has  resigned,  and  his  place  is  to 
be  filled  by  Professor  Griitzner,  of  Bern. 

More  Cholera  Commissions. — ^The  Roumanian  Gov- 
ernment has  sent  Dr.  Maccovich  as  a  "commission"  to 
Marseilles,  in  order  to  study  the  cholera. 

A  Plague  Commission. — The  Russian  Government 
has  sent  Dr.  Batorsky  to  Bagdad,  for  the  purpose  of  in- 
vestigating the  plague,  now  prevalent  there. 

A  London  (Canada)  Medical  Society. — The  med- 
ical men  of  London,  Canada,  have  recently  met  and  or- 
ganized an  association  for  social  and  scientific  purposes. 

Women  as  Internes  in  the  Paris  Hospitals. — 
It  is  stated  in  the  Revue  Midicale^  that  women  are  soon 
to  be  admitted  to  the  examinations  for  positions  as  in- 
ternes in  the  Paris  hospitals. 

The  Characteristic  Enterprise  of  The  Medical 
Record  finds  another  illustration  in  its  cable  report,  in 
its  issue  of  2d  inst,  of  the  proceedings  of  the  British 
Medical  Association  at  its  meeting  in  Belfast,  Ireland,  on 
July  29th  and  30th. — Medical  Age. 

Journalistic  Changes. — The  Canadian  Practitioner 
has  a  new  editorial  staff.  Drs.  Cameron  and  Nevitt  have 
resigned,  and  Drs.  J.  £.  Graham  and  W.  H.  B.  Aikins 
have  taken  their  places.  Dr.  Wright  continues  upon  the 
stafil  The  Pacific  Medical  and  Surgical  Journal  and 
the  Western  Lancet  have  consolidated. 

ViRCHOw  vs.  Pettenkofer. — Professors  Virchow  and 
Pettenkofer  are  busily  arguing  with  each  other  upon  the 
subject  of  cholera.  The  gist  of  their  differences  lies  in 
this  :  Virchow  is  a  contagionist,  Pettenkofer  is  a  localist. 
That  is  to  say,  the  latter  believes  that  no  specific  germ 
can  produce  cholera  unless  there  is  a  specific  local  con- 
dition to  favor  it. 

Nepotism  at  the  Massachusetts  General  Hos- 
pital.— Some  interesting  correspondence  has  been  going 
on  in  the  Boston  Medical  and  Surgical  Journal  reizAyt 
to  the  above  subject.  It  is  charged  that  the  medical 
board  appoint  as  internes^  members  of  their  own  or  their 
friends*  families,  and  that  appointments  are  matters  of 
personal  favoritism  rather  than  of  real  merit.  There 
seems  to  be  some  truth  in  the  charge,  but  it  is  not  denied 
that  the  internes  are  good  men. 

The  First  Case  of  Yellow  Fever  which  has  ap- 
peared in  this  country  during  the  present  season  was 
reported  on  August  15th,  and  occurred  at  Key  West, 
Fla.  The  patient  was  an  officer  on  board  the  U.  S. 
vessel  Galena.  The  Galena  was  ordered  at  once  to 
Portsmouth,  N.  H.,  while  the  patient  was  taken  in  charge 
at  Key  West  It  is  now  six  days  since  the  case  was  re- 
ported, and  there  is  as  yet  no  further  appearance  of  the 
disease. 

The  Medical  Details  of  Cannibausm. — ^The  ac- 
count of  the  examination  of  the  body  of  Lieutenant  Kis- 


lingbury,  as  given  by  two  physicians  of  this  State,  and 
telegraphed  all  over  the  country,  were  shocking  m  the 
extreme.  We  cannot  see  the  necessity  of  medical  men 
lending  their  special  knowledge  for  the  elaboration  of 
horrible  details  regarding  the  supposed  Arctic  cannibal- 
ism. Is  science  or  the  world  any  better  for  knowing 
that  the  pectorales  muscles  were  eaten  and  the  recti  ab- 
dominales  were  not  ? 

The  Head  of  Campi. — ^The  experiments  of  Dr.  La^ 
borde,  which  we  have  already  referred  to,  upon  the  head 
of  the  assassin  Campi,  were  rather  tame  after  alL  It 
was  an  hour  and  a  half  after  the  execution  before  fresh 
blood  was  injected  into  the  carotid  arteries.  The  face 
naturally  became  suffused,  some  electrical  reactions  were 
obtained,  but  no  reactions  of  the  special  senses,  and 
no  reflexes.  The  assassin  had  agreed  before  death  to 
make  some  signal  if  the  transfusion  brought  back  any 
consciousness.  Campi's  brain  was  turned  over  to  the 
Anthropological  Society. 

Adulterated  Beer. — Imported,  and  especially  Bava- 
rian beer,  has  been  supposed  to  be  exceptionally  pure. 
This  is  not  the  case,  however,  according  to  recent  reports. 
These  say  that  so  many  complaints  have  been  made  of 
adulterated  beer  that  the  Bavarian  Government  has  taken 
the  matter  in  hand  and  ordered  an  investigation  to  be 
made.  All  breweries  are  to  be  subject  to  inspection. 
At  Memmingen  the  inspection  has  resulted  in  the  con- 
demnation of  thirty-three  brewers  to  pay  fines  ranging 
from  $50  to  $250,  according  to  the  degree  of  impurity  of 
their  beer.  Three  others  were  sentenced  to  eight  months 
in  prison. 

The  Canadian  Medical  Association — The  Brit- 
ish Association  for  the  Advancement  of  Science.— 
The  Canadian  Medical  Association  meets  next  week, 
August  25th,  26th,  and  27th.  The  meeting  of  the  British 
Association  for  the  Advancement  of  Science  will  com- 
mence on  Wednesday  afternoon,  August  2  7th,  after  the 
close  of  the  Canada  meeting.  Over  fifty  of  the  phy- 
sicians and  surgeons  who  have  promised  to  come  out  for 
the  British  meeting,  have  been  invited  to  attend  the  Can- 
ada meeting,  and  more  than  half  have  accepted,  among 
them  being  Mr.  Lawson  Tait,  who  has  promised  to  de- 
liver an  address  on  ^'Abdominal  Surgery." 

A  Cure  for  Red  Noses. — ^The  sun  which  shines  for 
all  is  sometimes  a  factor  in  producing  red  noses.  It  is 
very  appropriate,  therefore,  that  the  New  York  Sun^ 
which  also  shines  for  all,  should  devote  its  columns  to 
discussing  remedies  for  the  congested  organ.  The  fol- 
lowing are  three  **  cures'*  suggested  by  as  many  corre- 
spondents : 

"  A  remedy  which  1  have  used  with  best  results  is  the 
following :  Take  of  vaseline  one  ounce,  precipitated 
sulphur,  two  drachms.  Mix  well  and  apply  to  the  affected 
part  night  and  morning,  nibbing  in  well.  Continae  the 
application  for  one  or  two  weeks  and  the  redness  will 
disappear.  Physician." 

**  For  the  benefit  of '  A  Reader/  Marshall  County,  W, 
Va.,  I  would  suggest  that  a  good  strong  brine  might 
effectually  and  permanently  cure  the  red  nose  of  vdiich 
he  complains.  W.  H.  H." 

"  Another  Plan.  A  remedy  for  red  noses.  Keep  on 
drinking  and  it  will  turn  purple.  Slap  Sticks." 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


211 


The  Cholera. — ^The  cholera  continues  to  decrease  in 
extent  and  violence  at  Toulon  and  Marseilles.  It  has, 
however,  now  spread  to  over  forty  places  in  France,  and 
to  a  iaige  number  of  places  in  Italy.  While  the  disease 
has  become  milder  in  the  two  cities  mentioned,  it  shows 
a  malignant  type  in  many  of  the  small  towns  which  it  has 
reached. 

The  First  Discoverer  of  the  Cholera  Germ. — 
Naturally,  the  questions  of  priority  as  to  the  discovery  of 
the  alleged  cholera  bacillus  now  appear.     A  correspond- 
ent of  Tike  Lancet  puts  in  a  claim  for  the  late  Professor 
Pacini,  of  Florence,  the  discoverer  of  certain  corpuscles 
in  the  skin  bearing  his  name.     In  1854  he  wrote  to  the 
Italian  Medical  Gazette  as  follows :  "  Examining  minutely 
the  diflferent  parts  of  the  gastro-enteric  tube  of  subjects 
dead  from  cholera  when  in  the  algid  state,  I  was  forced 
to  the  conviction  that  that  epithelial  lesion  is  covered  by 
nothing  but  a  very  simple  organism  of  extreme  tenuity, 
which  I  shall  call  '  microbe,'  a  term  generic  and  modem, 
and  with  special  reference  to  the  disease  in  question, 
*cholerigenous  microbe.'"      This  discovery  was   more 
quickly  and  thoroughly  appreciated  by  foreigners  than  by 
its  author's  own  countrymen,  and  in  1865,  on  the  next 
cholera  visitation,  Pacini  wrote  :  ''When  my  scientific  la- 
bors, having  made  the  tour  of  Europe,  will  have  returned, 
arrayed  in  foreign  garb,  to  Florence,  they  will  have  per- 
mission to  enter  the  schools,  and  then  we  shall  be  enjoy- 
ing the  tranquil  repose  of  Trespiano — in  our  grave,  in 
short"     This  bitter  forecast,  says  The  Lancet^  has  been 
verified  aloiost  to  the  letter,  Pacini's  doctrine,  rehabili- 
tated by  the  German  Cholera  Commission,  being  now 
adopted  by  his  compatriots  and  taught  in  the  Istituti 
Pathologici  of  Italy  a  year  after  his  death. 

We  must  dissent  from  the  opinion  that  Pacini  discovered 
the  cholera  bacillus.  He  very  likely  saw  some  minute 
organisms  in  the  intestine,  as  many  others  have  done,  but 
the  cholera  bacillus,  according  to  Koch's  description,  is 
revealed  by  a  one-twelfth  oil  immersion  with  an  Abbe 
condenser,  the  tissue  being  dried  and  stained  with  fiichsiu. 
It  is  quite  safe  to  say  that  Koch  is  the  Columbus  of  the 
Comma-Bacillus,  whatever  its  significance  may  turn  out 
to  be. 

Suggestions  Relative  to  Epidemic  Cholera. — The 
Massachusetts  State  Board  of  Health  has  issued  a  circu- 
lar under  the  above  title.  It  contains  an  excellent  account 
of  the  measures  to  be  taken  by  individuals  and  municipal- 
ities in  order  to  prevent  cholera.  The  following  disin- 
fectants are  recommended  :  For  clothing,  towels,  bedding, 
and  other  textile  fabrics,  a  solution  of  bichloride  of  mer- 
cury, I  part  to  1,000 ;  carbolic  acid,  i  part  to  30  of 
water.  Subjecting  to  a  temperature  of  at  least  212°  F. 
(100°  C.)  for  an  hour,  either  by  boibng  or  baking,  is  rec- 
ommended as  quite  efficient  when  practicable.  It  would 
be  better  still  to  burn  all  soiled  clothing.  For  water- 
dosets,  urinals,  sinks,  and  cesspools :  solution  of  bichlo- 
lide  of  mercury  (corrosive  sublimate),  i  part  to  1,000  of 
water ;  solution  of  carbolic  acid,  i  part  to  30  or  40 
of  water ;  solution  of  chloride  of  zinc,  i  part  of  liquor 
zinci  chloridi,  U.  S.  P.,  to  200  of  water.  For  the  disin- 
fection of  excreta  the  choleraic  discharges  should  re- 
ceive special  attention.  It  is  therefore  recommended 
that  such  discharges  be  received  in  metallic  or  earthen 


vessels  and  treated  with  the  solution  of  bichloride  of 
mercury,  i  to  1,000,  or  by  the  chloride  of  zinc  solution. 
Undoubtedly  the  better  mode  of  treating  the  discharges 
is  by  complete  destruction  by  fire.  For  this  purpose, 
when  practicable,  the  erection  of  small  fiirnaces,  stoves, 
or  crematories  is  desirable  wherever  cholera  hospitals 
are  established.  In  consequence  of  the  fluidity  of  the 
excreta  it  would  be  preferable  to  receive  them  into  saw- 
dust, or  other  light  combustible  material  previous  to 
burning.  Bodies  of  persons  deceased  firom  cholera  should 
be  wrapped  in  cloths  saturated  in  a  solution  of  bichloride 
of  mercury  previous  to  burial.  For  the  disinfection  of 
houses  sulphur  is  recommended,  as  advised  in  previous 
circulars  of  the  board.  Efifective  disinfection  by  burning 
sulphur  requires  eighteen  ounces  to  each  space  of  one 
thousand  cubic  feet.  The  sulphur  should  be  broken  in 
small  pieces,  burned  over  a  vessel  of  water  or  sand,  so 
as  to  avoid  danger  from  fire,  and,  if  the  room  is  large,  it 
should  be  put  in  separate  vessels  in  different  places.  The 
room  should  be  tightly  closed  for  six  hours,  and  then 
aired ;  it  is  better  that  the  room  should  be  warm  than 
cold.  Of  course,  efficiently  disinfected  air  is,  during  the 
process  of  disinfection,  irrespirable.  Most  articles  may 
be  disinfected  in  this  way,  if  hung  up  loosely  in  the  fumi- 
gated chamber,  although  it  would  be  an  additional  safe- 
guard to  expose  anything  thick,  like  a  bed-mattress,  to 
prolonged  heat  at  a  temperature  of  240^  F.;  and,  indeed, 
keai  must,  with  our  present  knowledge,  be  considered 
the  best  disinfectant.  With  this  end  in  view,  local  boards 
of  health  are  advised  to  procure  furnaces  and  laundries, 
as  is  commonly  done  in  other  countries,  to  be  used  for 
the  sole  purpose  of  disinfecting  articles  which  have  been 
exposed  in  the  infectious  diseases,  as  reconmiended  in 
the  "  Ninth  Annual  Report  of  the  State  Board  of  Health'' 
(pp.  255  et  seq.).  Of  course,  a  much  simpler  disinfect- 
ing furnace  than  that  described  will  answer  every  purpose. 
For  ordinary  use,  in  disinfecting  houses,  the  sulphur  pro- 
cess is  thf  best. 

Prince  Bismarck's  Physician,  Dr.  Schweininger, 
who  was  some  time  ago  made  a  professor,  has  now^  it  is 
said,  been  given  an  order  of  nobility  and  made  Professor  in 
the  Faculty  of  the  Berlin  University,  with  authority  to  de- 
liver certain  courses  at  Charity.  Apropos  of  Dr.  Schwein- 
inger,  the  German  papers  publish  in  the  humorous 
column  the  following  story :  '<  A  servant  in  Munich  was 
showing  the  sights  to  a  country  visitor.  The  latter 
wanted  to  know  all  about  the  figures  and  statues  on  the 
University  Building.  Rather  than  confess  ignorance 
his  city  friend  gave  the  names  of  distinguished  contem- 
poraries to  the  various  gods,  goddesses,  and  other  im- 
mortals in  stone.  'And  that  figure,'  he  said  finally, 
pointing  to  a  very  classically  dressed  statue  on  the  facade 
of  the  left  wing,  'is  Dr.  Schweininger.'  'Aha I'  said 
the  admiring  visitor,  '  but  where  then  is  his  coat  ? ' 
*0h,'  replied  his  friend,  'since  he  cured  Prince  Bis- 
marck, the  people  have  sent  for  him  firom  all  over  the 
country,  and  he  has  had  to  travel  so  hard  that  he  has 
worn  off  his  clothes  ! ' " 

Criticising  the  Louisiana  State  Board  of  Health. 
— The  Mississippi  Valley  Medical  Monthly  thus  criticizes 
the  Louisiana  State  Board  of  Health,  which  started  off 
this  year  with  such  alluring  promises :   ^'  This  Board,"  it 


212 


THE  MEDICAL  RECORD. 


[August  23,  1884. 


says,  '*  has  neither  the  ability  (financial)  nor  the  authority 
to  enforce  such  quarantine  regulations  as  this  great  Valley 
has  a  right  to  demand.  Nevertheless,  in  the  face  of  these 
facts  and  in  opposition  to  the  expressed  will  of  the  National 
Board  of  Health,  the  Marine  Hospital  Service,  and  the 
Sanitary  Council  of  the  Mississippi  Valley,  together  with 
muttering  threats  of  shot-gun  quarantine,  this  Board  has 
persistently  arrogated  to  itself  the  right  to  enforce  its 
rules  and  compel  the  commerce  of  the  United  States  to 
yield  tribute  to  its  support.  It  has  disturbed  the  work- 
ings of  the  National  Board  of  Health  ;  has  rendered  the 
Marine  Hospital  Service  almost  powerless  in  that  locality, 
and  has  done  much  to  prevent  the  enactment  of  proper 
laws  for  the  enforcement  of  quarantine  by  the  Congress 
of  the  United  States."  According  to  the  same  journal, 
the  Louisiana  State  Board  of  Health,  which  thus  under- 
takes to  guard  the  Mississippi  Valley,  receives  only  $6,000 
a  year  besides  **  a  scanty  and  contested  pittance  "  from 
quarantine  and  registration  fees. 

Regulating  MiDwivES  in  the  City  of  Berlin. — The 
following  regulations  have  been  adopted  by  the  Berlin 
Police  Department  They  contain  important  suggestions 
for  the  municipalities  in  this  country  :  '^  Midwives,  on  com- 
mencing practice,  are  to  notify  the  same  personally  to 
the  Bezirks-Physikus  within  fourteen  days,  and  at  the 
same  time  to  lay  before  him  (i)  their  license ;  (a)  the 
day-book ;  (3)  the  last  edition  of  the  Prussian  "  Hand- 
book of  Midwifery  for  Midwives "  ;  (4)  the  instruments 
prescribed  by  the  latter.  They  are  required]  to  treat 
their  cases  strictly  in  accordance  with  the  instructions 
given  in  the  handbook.  They  must  keep  a  day-book 
after  a  prescribed  pattern  in  which  cases  must  be  en- 
tered, and  they  must  till  up  the  columns  accurately,  or 
permit  the  medical  man  they  call  in  to  do  so.  Besides 
the  instruments  prescribed,  which  must  be  kept  clean  and 
ready  for  use,  they  must  always  have  such  disinfecting 
material  as  is  ordered.  Every  case  of  pueYp^ral  fever, 
as  well  as  every  maternal  fatality,  must  be  notified  with- 
in twenty-four  hours  of  verification  of  diagnosis  or  death 
to  the  Royal  Sanitary  Commission.  They  must  also 
submit  to  subsequent  examinations  once  in  three 
years." 


THE  SIMS  MEMORIAL  FUND. 

To  the  Medical  Profession  and  Others  throughout  the 
World: 

The  great  achievements  of  Dr.  J.  Marion  Sims  call 
for  some  more  lasting  testimonial  than  obituaries  and 
eulogies.  To  him  medical  science  is  indebted  for  much 
brilliant  and  original  work,  especially  in  gynecological 
surgery.  Those  who  have  been  benefited  by  his  teach- 
ings and  new  operations,  and  such  as  have  had  the  direct 
advantage  of  his  personal  skill  are  among  the  first  to 
recognize  and  acknowledge  this  debt 

To  him  is  due  the  honor  of  giving  the  first  strong  im- 
pulse to  the  study  of  gynecological  surgery  in  America. 

It  is  believed  that  the  medical  profession  everywhere, 
the  vast  number  of  women  who  owe  their  relief  firom 
suffering  directly  to  him,  and  those  who  realize  the 
benefits  he  first  made  possible,  will  gladly  unite  thus  to 
honor  the  man  through  whose  originid  and  inventive  ge- 
nius such  blessings  have  been  conferred  upon  humanity. 

At  the  suggestion  of  many  friends,  therefore,  the  sub- 
joined committee  has  been  organized,  and  it  is  proposed 


that  a  suitable  monument  be  erected  to  his  memory  in 
the  city  of  New  York. 

To  this  end  the  active  co-operation  of  the  medical 
profession  and  the  many  other  friends  of  Dr.  Sims 
throughout  the  world  is  respectfully  solicited.  Contribu- 
tions of  one  dollar  and  upward  may  be  forwarded  to  the 
journal  which  has  been  constituted  the  treasury  of  this 
fund — The  Medical  Record,  New  York. 

FORDYCE  BARKER,  M.D.,  Chairman, 
GEORGE  F.  SHRADY,  M.D.,  Secretary. 

Thomas  Addis  Emmet,  M.D.,  New  York. 
T.  Gaillard  Thomas,  M.D.,  " 

William  T.  Lusk,  M.D.,  '* 

William  M.  Polk,  M.D.,  " 

Paul  F.  MundA,  M.D.,  « 

S.  O.  Vander  Poel,  M.D.,  " 

Frank  P.  Foster,  M.D.,  " 

E.  S.  Gaillard,  M.D.,  «* 

Alex.  J.  C.  Skene,  M.D.,  Brooklyn,  N.  Y. 
Samuel  D.  Gross,  M.D.,  Philadelphia,  Pa. 
William  Gk)ODELL,  M.D.,  " 

James  R.  Chadwick,  M.D.,  Boston,  Mass. 
William  H.  Byford,  M.D.,  Chicago,  IlL 
A.  Reeves  Jackson,  M.  D.,       '' 
Thad.  a.  Reamy,  M.D.,  Cincinnati,  O. 

C.  D.  Palmer,  M.D.,  " 

George  J.  Engelbcann,  M.D.,  St.  Louis,  Mo. 
R.  Beverley  Cole,  M.D.,  San  Francisco,  CaL 
H.  F.  Campbell,  M.D.,  Augusta,  Ga. 
R.  K  Maury,  M.D.,  Memphis,  Tenn. 
E.  S.  Lewis,  M.D.,  New  Orleans,  La. 
J.  T.  Searcy,  M.D.,  Tuskaloosa,  Ala. 
R.  A.  Kinloch,  M.D.,  Charleston,  S.  C. 
Hunter  Maguire,  M.D.,  Richmond,  Va. 
S.  C.  Busey,  M.D.,  Washington,  D.  C. 
Harvey  L.  Byrd,  M.D.,  B^timore,  Md. 
W.  T.  Howard,  M.D.,  *« 

D.  W.  Yandell,  M.D.,  Louisville,  Ky. 
Seth  C.  Gordon,  M.D.,  Portland,  Me. 
Frank  E.  Beckwith,  M.D.,  New  Haven,  Conn. 
A.  W.  Knox,  M.D.,  Raleigh,  N.C. 

L.  W.  Oakley,  M.D.,  Elizabeth,  N.  J. 
A.  T.  Woodward,  M.D.,  Brandon,  Vt. 
Albert  H.  Crosby,  M.D.,  Concord,  N.  H. 

E.  S.  DuNSTER,  M.D.,  Ann  Arbor,  Mich. 
Alex.  J.  Stone,  St  Paul,  Minn. 


List  of  Additional  Subscribers. 

South  Carolina  Medical  Association $100  00 

S.  Logan,  M.D.,  New  Orleans,  La 5  00 

R.  H.  Day,  M.D.,  Baton  Rouge,  La i  00 

Thos.  Hebert,  M.D.,  New  Iberia,  " i  00 

F.  Formento,  M.D.,  New  Orleans,  La i  00 

J.  C.  Bickham,  M.D.,         "               «    S  ^ 

W.  D.  White,  M.D.,  Abbeville,         "    i  00 

L.  Cheves  Tibo,  M.D.,  New  Orieans,  La i  00 

J.  H.  Bemis,  M.D.,                 "                ** i  00 

J.  S.  Fish,  M.D.,  Rapides,  La. .    i  00 

F.  W.  Parham,  M.D.,     New  Orleans,  La i  00 

G.  Breaux  Underbill,  M.D.,     "              ** i  00 

H.  D.  Bruns,  M.D.,                  **             ** i  00 

J.  P.  Davidson,  M.D.,              **              " i  00 

S.  E.  Chaille,  M.D..                  "              " i  00 

A.  C.  Love,  M.D.,                   "              " 5  00 

Dr.  Fox,  Opelousas,  La. 100 

E.  Louchon,  M.D.,  New  Orleans,  La 25  00 

G.  B.  Laurason,  M.D.,      *'               *' 100 

A.  W.  de  Rialdes,  M.D.,  "               " 5  00 

Henry  Bezon,  M.D.,         "  " 2  00 

T.  G.  Richardson,  M.D.,  **               ** 5  ^ 

A.  B.  Miles,  M.D.,            «'               " 5  ^o 

E.  S.  Lewis,  M.D.,            "                " 54  00 


August  23.  X884.] 


THE  MEDICAL  RECORD. 


213 


l^eprorts  at  SiocutUs. 
|nteMiati0tmI  gJtejflical  &angKf^6B. 

EIGHTH   SESSION, 
Held  at  Copenhagen^  Denmark,  August  10-16,  1884, 


BY  CABLE  TO  THE  MEDICAL  RECORD. 


(Concfasded  fiom  page  x88.) 


Thursday,  August  14TH — Fifth  Day. 
At  the  General  Session,  3.30  p.m.,  Sir  William  Gull, 
of  London,  delivered  an  address 

ON  THE   INTERNATIONAL  COLLECTIVE    INVESTIGATION    OF 
DISEASE. 

Speaking  of  the  importance  of  the  subject,  he  main- 
tained that  its  proper  consideration  promised  greater  ad- 
vances in  knowledge  than  by  the  ordinary  methods.  The 
time  had  come  when  organized  co-operation,  as  against 
scattered  individual  efforts,  should  be  encouraged.  This 
was,  in  iajct^  one  of  the  purposes  of  the  Congress  and 
other  similar  medical  organizations.  The  field  of  scien- 
tific medicine  was  too  large  to  be  compassed  by  any 
other  means.  The  amount  of  work  that  could  be  ac- 
complished by  a  systematic  direction  of  numerous 
workers  was  practically  without  limit,  and  was  proportion- 
ately valuable.  By  such  means  facts  could  be  accumu- 
lated on  a  large  scale,  and  be  utilized  accordingly.  In 
conclusioii  he  referred  in  detail  to  the  admirable  work  of 
the  Committee  on  Collective  Investigation  in  the  British 
Medical  Association,  and  urged  that  the  scheme  be  ex- 
tended throughout  the  scientific  world,  in  order  that  the 
results  might  be  centralized,  if  need  be,  in  the  different 
medical  congresses  hereafter  to  be  held.  The  subjects 
of  acute  rheumatism  and  contagiousness  of  phthisis  had 
already  been  worked  up  by  different  committees  of  in- 
vestigation, and  had  given  some  remarkably  valuable 
results.  The  English  and  German  Committees  had  both 
chosen  the  latter  subject,  and  their  conclusions  were 
strikingly  consistent. 

MEETINGS  OP  SECTIONS. 

Section  on  Surgery. — ^There  was  a  discussion  of  the 
subject  of 

ANTISEPTICS    IN   SURGERY. 

fP^  Professor  Lister,  of  London,  being  absent,  the  discussion 
was  opened  by  Professor  Esmarch,  of  Kiel,  who,  after 
some  general  remarks  upon  the  principle  of  antiseptics, 
alluded  to  the  advantage  of  permanent  dressings  for 
wounds.  The  rule  was  to  thoroughly  cleanse  and  disin- 
fect the  parts  and  then  seal  them  with  antiseptic  coverings 
to  prevent  the  subsequent  entrance  of  germs.  This  dress- 
ing was  kept  applied  as  long  as  possible,  consistent  with 
cleanliness  and  the  absence  of  constitutional  disturbance. 
The  general  practice  of  German  surgeons  was  to  use 
catgut  ligatures,  the  latter  being  completely  absorbed  in 
die  wounds.  Professor  Esnuurch  applies  the  permanent 
dressings  after  main  vessels  are  secured  and  before  the 
removal  of  the  tourniquet   ^  He  does  not  think  it  neces- 


sary in  the  large  majority  of  cases  to  use  drainage-tubes, 
but  supports  the  deeper  parts  and  keeps  them  m  contact 
by  pressure.  Openings  are  left  for  the  escape  of  drain- 
age into  the  bandages,  which  are  sterilized  by  dry  heat 
and  corrosive  sublimate.  Other  antiseptics  are  occa- 
sionally used,  but  preference  is  alwajrs  given  to  bichloride 
of  mercury.  The  parts  are  sometimes  supported  by 
glass  splints  until  healing  is  accomplished  by  first  inten- 
tion. The  general  treatment  carried  out  is  based  upon 
the  grand  principles  of  absolute  rest,  perfect  cleanliness, 
and  thorough  drainage. 

Professor  Mosetig-Moorhof,  of  Vienna,  advocated  the 
use  of  iodoform  as  an  antiseptic  in  the  dressings,  but  pre* 
ferred  simple  cold  water  during  operations. 

Dr.  Schede,  of  Hamburg,  thought  well  of  iodoform, 
but  his  best  results  were  obtained  when  corrosive  subli- 
mate was  used.  With  the  latter  erysipelas  vanished  and 
septic  troubles  were  almost  unknown.  He  was  in  the 
habit  of  employing  the  corrosive  sublimate  solution  in 
the  proportion  of  one  to  five  hundred,  and  had  yet  to 
meet  with  the  first  case  in  which  indications  of  poison- 
ing showed  themselves,  although  there  were  sometimes 
symptoms  of  tenesmus.  Even  children  bore  the  corro- 
sive sublimate  dressing  without  any  bad  results. 

The  general  principles  of  antiseptic  treatment  were 
endorsed  by  Professors  Mikulicz,  Neudorfer,  Buchanan, 
and  Schelkley,  who  followed  with  remarks,  the  only  dif- 
ferences noted  being  in  the  methods  of  application. 

Professor  Koeberl6,  of  Strasburg,  used  only  clean  linen 
with  which  he  wiped  the  wounds,  and  had  noticed  no 
erysipelas  when  the  open  method  of  treatment  was  fol- 
lowed. 

Professor  Plum  said  that  the  Danish  surgeons  agreed 
in  the  main  with  their  German  confreres,  although  the 
cost  was  somewhat  of  an  objection  to  Esmarch's  plan. 
Cleanliness  was,  after  all,  at  the  bottom  of  all  antisepsis, 
and  the  soap  and  the  brush,  when  properly  employed, 
would  work  wonders.  It  was  a  question,  after  all,  how 
simple  we  could  make  the  matter,  and  how  we  could 
divest  ourselves  of  useless  paraphernalia. 

Section  on  Medicine. — Professor  Lupine,  of  Lyon,  read 
a  paper  entitled  *^  Clinical  Observations  on  the  Toxical 
Principles  which  are  formed  in  Living  Organisms,"  giving 
a  full  r/sum/  of  the  literature  of  the  subject,  and  present- 
ing illustrations  of  the  relations  of  cause  and  effect  on 
the  commoner  variety. 

Professor  Leibermeister,  of  Tubingen,  followed  with  a 
communication  on  the  antipyretic  treatment  of  acute 
infectious  diseases,  advocating  the  utility  of  employing 
the  different  well-known  methods  in  particularly  well- 
selected  cases. 

The  subject  of  antiseptic  treatment  of  the  same  dis- 
eases was  next  presented  by  Professor  Bouchard,  of 
Paris,  who  also  discussed  the  different  methods  and  their 
applicability  to  individual  cases. 

A  general  discussion  then  followed,  in  which  Profes- 
sors Roth6,  Lepine,  and  Pribram  joined* 

Professor  MacEwen,  of  Glasgow,  read  a  paper  on  "  Oi^ 
thopedic  Osteotomy,"  which  was  discussed  by  Professors 
Agston,  Chiene,  Schede,  and  Mr.  Bryant  and  Dr.  Robin. 
The  general  sentiment  was  in  favor  of  MacEwen's  opera- 
tion in  proper  cases. 

Section  on  Ophthcdmology.-^VK^xs  read  :  "  Determin- 


214 


THE  MEDICAL  RECORD. 


[August  23,  i884t 


ation  of  Refraction  by  Ophthalmoscope,"  by  Professor 
Schmidt-Rimpler,  of  Marburg.  This  paper  was  duly 
discussed  by  Dr.  Noyes,  Mr.  Berry,  Dr.  Yuler,  Sattler, 
Grut,  and  Liebreich.  On  the  '*  Artificial  Maturation  of 
Cataract,''  by  Dr.  Ed.  Meyer,  Paris ;  discussed  by  Drs. 
Moore  and  Samuelson.  On  **  Infantile  Blennorrhoea,  its 
Prevention  and  Treatment,"  by  Dr.  Christensen,  of 
Copenhagen.  On  **  Inflammation  of  the  Eye,"  by  Dr. 
Martin,  of  Bordeaux. 

Section  on  Diseases  of  Children. — Prof.  Hirschsprung, 
of  Copenhagen,  presided.  A  paper  was  read  by  Dr.  P. 
Rupprecht,  of  Dresden,  on  **  The  Choice  of  Antiseptics 
in  the  Treatment  of  Wounds  in  Children."  He  was  fol- 
lowed by  Dr.  Sofus  Meyer,  of  Copenhagen,  who  read  a 
paper  on  the  **  Prophylactic  Treatment  of  the  Ophthal- 
mo-blenorrhcea  of  the  New-bom."  A  paper  was  read  by 
the  President,  Prof.  Hirschsprung,  on  "Intestinal  Invagi- 
nation and  its  Comparative  Frequence  in  Different 
Countries  ; "  and  one  on  the  same  subject  by  Prof.  Rib- 
bing, of  Lund.  Dr.  A.  Jacobi,  of  New  York,  read  a  pa- 
per on  "  Primary  Sarcoma  of  the  Kidney  in  the  New- 
born.*' 

A   GRAND   BANQUET. 

At  five  o'clock  in  the  afternoon  a  grand  banquet  was 
tendered  the  members  of  the  Congress  by  the  Municipal 
Council  of  Copenhagen.  Fourteen  hundred  guests  were 
present.  The  tables  were  set  in  a  large  tent  erected  for 
the  occasion  upon  the  Custom  House  quay.  The  in- 
terior of  the  tent  was  decorated  with  the  flags  and  coats- 
of-arms  of  the  different  nations.  The  tables  were  pro- 
fusely ornamented  with  flowers,  another  evidence  of  the 
warm  hospitality  of  the  Danish  ladies.  After  the  courses 
had  been  finished,  speeches  were  made  by  President 
Panum,  and  by  Pasteur,  Paget,  and  Virchow.  Many  of 
the  guests  went  upon  an  excursion  by  steamers  to  Tivoli. 
The  entertainments  of  the  evening  closed  with  a  grand 
display  of  fireworks  and  electric  lights.  The  whole  city 
joined  enthusiastically  in  the  spectacle. 


Friday,  August  15TH — Sixth  Day. 

PROFESSOR  VIRCHOW 'S  ADDRESS. 

Professor  R.  Virchow,  of  Berlin,  delivered  an  address 
entitled  "  Metaplasia." 

He  said  that  at  the  beginning  of  the  present  century 
the  processes  of  life  were  considered  to  be  merely  chemi- 
cal Life  and  thought  were  bound  to  certain  matter  in 
the  blood,  which,  becoming  solid,  formed  tissues.  Even 
Schwann  said  that  cells  were  formed  by  a  sort  of  crys- 
tallization of  the  plasma.  These  chemical  doctrines 
were  of  English  origin.  John  Hunter  spoke  of  *'  plastic 
lymph."  These  doctrines  were  supported  by  the  then 
physiological  views  of  outrition.  The  plasma  was  thought 
to  supply  food  directly  to  the  tissues,  in  fine,  to  feed 
them.  As  a  consequence,  the  healing  art  was  thought 
to  consist  mainly  in  regulatiag  nourishment,  1.^.,  the  sup- 
plies furnished  the  plasma.  Virchow  made  the  first  step 
-toward  the  cellular  pathology  thirty  years  ago,  when  he 
announced  his  doctrine  omnis  celiula  e  cellula.  He  said 
that  the  task  for  nourishment  was  to  keep  the  cells  alive. 
These  cells  then  formed  tissues  and,  indeed,  to  them 
belonged  all  the  formative  fiinctions.  The  speaker  con- 
trasted the  nutritive  with  the  formative  processes. 


Difierences  in  the  matter  supplied  afiected  nutrition, 
but  the  formative  process  was  the  same,  with  the  most 
varied  nourishment  All  organic  operations,  said  the 
speaker,  occur  within  cells,  never  outside  of  them.  The 
speaker  defined  automatic  nourishment  of  cells,  showing 
that  their  nutrition  supply  was  regulated  by  certain  auto- 
matic checks,  so  as  to  be  kept  at  the  proper  mean.  He 
then  spoke  of  the  phenomena  of  growth  and  the  produc- 
tion of  new  tissue  forms,  to  which  he  gave  the  tenn 
''metaplasia."  He  described  the  various  theories  of 
bone  formation,  and  showed  the  difference  between  ossi- 
fication and  calcification.  He  spoke  also  of  the  fomia- 
tion  of  bony  marrow,  which  being  a  tissue  of  changing 
form,  furnishes  a  good  example  of  metaplasia.  He  ex- 
plained  the  pathology  of  osteo-porosis  and  osteo-malada. 
He  referred  briefly  to  the  subject  of  the  development  of 
tumors.  Lastly  he  spoke  of  the  white  blood-globules, 
and  of  their  ability  to  form  new  tissue.  In  them  meta- 
plasia reached  its  fiirthest  limits. 

Dr.  Lewis  A.  Sayre,  of  New  York,  gave  some  demon- 
strations of  the  application  of  his  plaster-of-Paris  bandage 
for  the  treatment  of  spinal  disease,  and  was  followed  by 
Professor  Tommasi  Crudeli,  who  showed  some  micro* 
scopic  specimens  of  red  blood-corpuscles  taken  from  the 
human  subject  suffering  from  malaria.  The  infected 
corpuscles  responded  to  aniline  and  some  of  these  were 
seen  to  contain  colored  particles.  These  he  consid- 
ered germs  of  bacilli.  Healthy  corpuscles  refused  the 
stain  and  contained  none  of  the  particles  referred  to. 

MEETINGS   OF   SECTIONS. 

Section  on  Medicine. — Professor  Rosenstein,  of  Ley- 
den,  presented  a  paper  on  "  Malarious  Infection  in  Man, ' 
which  was  discussed  by  Professors  Flint,  Ewald,  and 
Mahomed.  Professor  Grancher,  of  Paris,  next  read  a 
paper  on  "Subacute  Pneumonia,"  dwelling  mostly  on  its 
clinical  significance. 

Section  on  Ophthalmology. — Dr.  Gayet,  of  Lyons,  read 
a  paper  on  "  The  Results  of  Great  Losses  of  the  Sub- 
stance of  the  Cornea,"  which  was  discussed  by  Professors 
Berry,  Grut,  Noyes,  and  Nicden.  The  subject  of  "  Latent 
Squint "  was  presented  by  Dr.  Grut,  of  Copenhagen,  and 
was  discussed  by  Dr.  Noyes  and  others. 

Section  on  Diseases  of  Children, — In  the  morning 
there  was  a  joint  session  with  the  Section  on  Hygiene, 
and  in  the  afternoon  the  regular  session  was  held. 

Dr.  Schepelem,  of  Refsnaes,  Denmark,  read  a  pa- 
per on  "The  Treatment  of  Chronic  Diseases  of 
Children  at  Sea-Coast  Hospitals,"  which  was  followed 
by  a  communication  from  Dr.  Engelsted,  of  Copenhagen, 
on  ''  Sea-Coast  Hospitals  for  Scrofulous  Children,"  es 
pecially  with  regard  to  the  Refsnaes  Hospital  in  Den 
mark. 

In  the  afternoon  session.  Dr.  Rauchfuss,  of  St.  Peters 
burg,  read  a  paper  on  **  Croup  Clinically  Considered  as 
a  Well-limited  Morbid  Entity."  This  was  discussed  by 
Professor  Virchow  and  others. 

RECEPTION     BY    THE    KINGS   AND   QUEENS   OF   DENBCARK 
AND   GREECE. 

In  the  evening  a  reception  was  given  the  Congress  at 
the  Christiansborg  Palace,  by  the  Kings  and  Queens 
of  Denmark  and  Greece.    The  affair  was  a  brilliant  one] 


August  7$,  1884.J 


THE  MEDICAL  RECORD. 


215 


and  the  most  bountiful  hospitality  expressed  the  royal 
appreciation  of  the  distinguished  guests.  After  the  en- 
joyment of  a  sociable  converse  and  musical  concert,  the 
members  were  entertained  at  a  sumptuous  supper,  at  which 
the  King  of  Denmark  proposed  the  toast  of  the  foreign 
members  which  was  felicitously  replied  to  by  Sir  William 
GulL 


Saturday,  August  i6th — Seventh  Day. 

THE    next    congress   TO   MEET   IN   WASHINGTON,    1 887. 

At  3.30  P.M.  the  Congress  took  up  the  subject  of  the 
place  of  next  meeting.  The  Committee  to  whom  the 
subject  was  referred,  reported  back  a  recommendation 
that  the  invitation  to  hold  the  next  meeting  in  Washing- 
ton, U.  S.,  be  accepted.  There  was  a  warm  debate  over 
the  sabject ;  the  English  members  strongly  supported  the 
decision,  however,  and  it  was  finally  voted  by  a  consider- 
able majority  to  meet  in  Washington  in  1887.  After  the 
rote  was  announced,  Dr.  J.  S.  Billings  thanked  the  Con- 
gress in  warm  terms,  and  expressed  his  gratitude  at  the 
hospitality  which  had  been  extended  to  the  guests.  He 
was  followed  by  Virchow  and  Sir  Risdon  Bennett 

The  General  Session  concluded  this  day  by  congratu- 
latory addresses  in  the  different  official  languages.  In 
French,  by  Professor  Rauchfuss ;  in  English,  by  Profes- 
sor JacoU  ;  and,  in  German,  by  Professor  Hirschsprung. 

Professor  Panum  closed  the  Congress  at  five  o'clock. 

SECTION   WORK. 

Section  on  Diseases  of  the  Eye, — Dr.  Bjemim,  of 
Copenhagen,  read  a  paper  on  ''  Refraction  in  Infants.'' 

Professor  Holmgren,  of  Upsala,  read  a  paper  on  the 
"Color  Sense." 

Mr.  Yuler,  of  London,  demonstrated  the  use  and  ad- 
vantages of  McHardy's  perimeter  and  of  Frost's  artificial 
eye. 

Dr.  Klebs  showed  the  method  of  using  the  electro- 
magnet in  removing  bits  of  iron  from  the  eye. 

Section  an  Medicine. — Dr.  Proschowsky  gave  a  dem- 
onstration of  sphygmographic  and  cardiographic  tracings. 

Dr.  Job.  Butzen,  of  Copenhagen,  read  a  paper  on 
"The  Different  Action  of  the  Japaconitine,  the  Pseuda- 
conitine,  the  French  and  the  German  Aconitine." 

Dr.  Roussel,  of  Paris,  read  papers  on  the  ''  Direct 
Transfiision  of  Living  Blood,"  and  upon  <*  Medical 
Hypodermic  Injections." 

Dr.  Maurice  Dupont,  of  Paris,  read  a  paper  on  the 
"Medical  Use  of  Condensed  Air  in  the  Form  of  Baths 
and  Douches."  He  showed  illustrations  of  his  new  ap- 
paratus. 

Professor  Granger-Stewart,  of  Edinburgh,  read  a  paper 
on  the  "  Influence  of  Acute  Infectious  Diseases  upon 
the  Kidneys  and  their  Functions." 

There  was  a  joint  session  of  the  Sections  on  Dis- 
eases of  Children  and  Hygiene;  the  papers  read 
were  as  follows :  "  The  Normal  Increase  of  Weight 
tfirough  the  Latter  Childhood,"  by  Mr.  Mating  Hansen 
and  Dr.  Wahl,  of  Denmark  ;  "  Meningitis  Tuberculosa 
in  the  First  Year  of  Life,"  by  Dr.  Medin,  of  Stockholm ; 
on  the  "  Influence  of  Cold  on  Diseases  of  Children,"  by 
Professor  Logroux ;  on  an  "  Easily  Curable  Form  of  In- 
fantile Spinal  Paralysis,"  by  Professor  d'Espine. 


At  one  o'clock  the  various  sections  adjourned,  and 
after  a  lunch  visited  several  of  the  hospitals  of  the  city. 

EVENING   ENTERTAINMENTS. 

In  the  evening  a  reception  was  given  at  the  National 
Establishment  It  was  preceded  by  a  concert  and  fol- 
lowed by  a  ball  and  supper.  The  total  number  of  guests 
present  was  eighteen  hundred. 

The  attendance  in  nationalities  was  as  follows  :  Danes, 
450 ;  Swedes,  150 ;  Americans,  64 ;  English,  120 ; 
French,  118;  Germans,  234;  Austrians,  35. 

The  Congress  is  looked  upon  as  a  decided  success,  and 
as  having  been  most  admirably  managed.  The  social 
features  were  attractive,  but  the  hospitalities  were  judi- 
ciously lavished,  so  as  not  to  interfere  and  crowd  out  the 
scientific  work. 


©Wtttaxrs. 


JOSEPH  JANVIER  WOODWARD,  M.D., 

PHILABBLPHIA,  PA. 

Col.  Joseph  Janvier  Woodward,  Surgeon  in  the  United 
States  Army,  died  Tuesday  morning  near  Philadelphia. 
He  was  born  in  that  city  in  1832.  He  received  his  edu- 
cation at  the  Philadelphia  Central  High  School,  where  he 
was  given  the  degree  of  A.  B.  in  1850,  and  that  of  A.  M. 
in  1855,  having  acted  as  the  valedictorian  of  his  class. 
After  receiving  the  first  degree  he  entered  upon  the  study 
of  medicine,  and  in  the  spring  of  1853  he  was  graduated 
from  the  University  of  Pennsylvania.  He  practised 
medicine  in  Philadelphia  until  August,  1861,  when  he 
was  appointed  an  Assistant  Surgeon  iq  the  regular  army. 
He  had  already  attained  considerable  prominence  in  his 
profession  through  the  publication  of  a  number  of  treat- 
ises on  abstruse  subjects,  especially  on  the  use  of  the 
microscope  in  the  practice  of  medicine.  He  subsequent- 
ly attained  such  eminence  in  this  particular  branch  that 
he  was  regarded  as  one  of  the  leading  authorities  in  cer- 
tain departments.  He  invented  an  instrument  by  which 
the  myopic  condition  of  the  eye  can  be  determined  with 
accuracy.  He  served  in  the  war,  and  distinguished  him- 
self by  his  gallant  conduct.  He  was  brevetted  Captain, 
Major,  and  Lieutenant-Colonel  on  March  13,  18651  for 
faithfiil  services. 

On  July  28,  1866,  he  was  made  Captain  and  Assistant 
Surgeon,  and  was  promoted  to  the  rank  of  Major  and 
Surgeon  on  June  26,  1876.  In  1866  he  was  selected  for 
the  important  dutyof  editing  the  "  Surgical  and  Medical 
History  of  the  Rebellion."  With  this  great  work  his 
name  will  always  be  inseparably  connected.  He  also  pub- 
lished a  number  of  papers  of  great  interest  and  value. 
Among  them  were  '*  Address  on  the  Medical  Staff  of  the 
United  States  Army."  "  Remarks  on  Croup  and  Diph- 
theria." "  Typho-Malarial  Fever ;  Is  it  a  Special  Type  of 
Fever  ?"  "  Remarks  on  Photojjraphic  Micrometry." 
"  Application  of  Photography  to  Micrometry,  with  Special 
Reference  to  the  Micrometry  of  the  Blood  in  Criminal 
Cases."  Report  on  "  Medical  Literature,"  and  report  on 
"  Causes  and  Pathology  of  Pyaemia."  When  President 
Garfield  was  shot,  on  July  2,  1881,  Dr.  Woodward  was  in 
Washington  in  the  Surgeon-General's  Bureau.  He  was 
one  of  the  surgeons  first  summoned  to  the  bedside  of  the 
wounded  President.  He  remained  in  constant  attendance 
there  until  September  7th,  when  he  retired  in  company 
with  Drs.  Reybum  and  Barnes. 

During  his  residence  in  Philadelphia  Dr.  Woodward 
was  a  member  of  the  Philadelphia  County  Medical  Soci- 
ety. He  was  also  a  member  of  the  American  Medical 
Association,  of  which  he  was  the  Second  Vice-President 
in  1875  ;  of  the  American  Academy  of  Sciences,  and  of 
the  Medical  Association  of  the  District  of  Columbia. 


2l6 


THE  MEDICAL  RECORD. 


[August  23, 1884, 


He  was  a  delegate  to  the  International  Medical  con- 
gress in  Philadelphia  in  1876. 

Dr.  Woodward  will  be  especially  remembered  for  his 
description  and  differentiation  of  typho-malarial  fevcT,  for 
his  remarkable  work  in  micro-photography,  for  his  micro- 
scopical studies  of  the  blood,  and  for  his  work  in  con- 
nection with  the  "  Medical  and  Surgical  History  of  the 
War." 

Dn  Woodward  was  a  man  of  positive  views  and  some- 
what abrupt  though  not  unpleasing  manners.  He  was 
an  untiring  and  conscientious  worker,  never  sparing  him- 
self, and  he  doubtless  wore  himself  out  before  his  time. 

Traits  de  l* Affection  Calculbuse  du  Foie.    Par  le 
DocTEUR  Jules  Cyr,  M^decin  Inspecteur  adjoint  a 
Vichy.     Paris:    V.   Delahaye   et   Lecrosnier.     1884. 
A  Treatise  on  Calculous  Disease  of  the  Liver. 
By  Dr.  Jules  Cyr. 
The  large  experience  which  Dr.  Cyr's  position  at  Vichy 
has  afforded  him  in  diseases  of  the  liver  entitles  him  to 
rank  as  one  of  the  authorities  in  such  affections.     The 
present  work  on  gall-stones  is  the  result  mainly  of  his 
own  observations,  and  in  consequence  bears  a  mark  of 
originality  which  adds  greatly  to  its  readableness.     At 
the  same  time  he  has  not  ignored  the  labors  of  others  in 
this  field,  so  that  the  monograph,  in  spite  of  the  author's 
modest  disclaimer,  may  justly  be  regarded  as  embodying 
all  that  is  of  value  respecting  biliary  calculi.     The  chap- 
ters on  diagnosis  and  treatment  are  especially  valuable. 

History  of  the  Discovery  of  the  Circulation  of 
the  Blood.     By  Henry  C.  Chapman,   M.D.,  Pro- 
fessor of  Institutes  of  Medicine  and  Medical  Jurispru- 
dence, in  Jefferson  Medical  College.     Philadelphia: 
P.  Blakiston,  Son  &  Co.     1884. 
An  interesting  essay,  in  which  the  author  shows  that  the 
discovery  of  the  circulation  of  the  blood,  like  all  other 
great  discoveries  and  movements,  was  the  result  of  a 
gradual  intellectual  growth  and  not  due  solely  to  the 
acumen  of  Harvey.     The  credit  of  the  discovery  does 
not  belong,  in   his  opinion,  to   England,  for  Harvey, 
though  by  accident  of  birth   an   Englishman,   was  m 
thought  Italian,  and  lived  and  died  a  student  of  Padua. 
Moreover  the  earlier  workers,  to  whose  investigations 
Harvey  was  indebted  for  the  ideas  which  led  to  his  grand 
discovery,  were  chiefly  Latins  or  Italians. 

The. Relation  of  Animal  Diseases  to  the  Public 
Health,  and  Their  Prevention.     By   Frank  S. 
Billings,  D.V.S.,  Graduate  of  the  Royal  Veterinary 
Institute  of  Berlin  ;  Member  of  the  Royal  Veterinary 
Association  of  the  Province  of  Brandenburg  ;  Honor- 
ary Member  of  the  Veterinary  Society  of  Montreal, 
Canada,  etc.    New  York  :  D.  Apple  ton  &  Co.     1884. 
The  question  of  the  susceptibility  of  man  to  infection 
from  animal  diseases  is  one  that  has  begun  to  attract 
considerable  attention  of  late  among  hygienists  and  phy- 
sicians, and  that  promises  to  become  of  still  greater  im- 
portance in  the  future.     The  more  the  subject  is  studied 
the  more  intimate  is  seen  to  be  the  relation  between  dis- 
eases of  man  and  of  the  lower  animals,  and  a  knowledge 
of  some  at  least  of  the  more  common  infectious  diseases 
of  animals  is  daily  becoming  more  necessary  to  the  phy- 
sician who  seeks  not  only  to  cure  but  to  prevent  sickness 
in  the  human  race.     On  this  account  the  appearance  of 
the  work  before  us  is  timely.     It  treats  of  the  higher 
purposes  of  veterinary  medicine  in  seeking,  by  a  careful 
study  of  animal  disease,  to  prevent  its  extension  to  man. 
The  work  is  divided  into  three  parts,  treating  respectively 
of  the  diseases  of  domestic  animals,  the  history  of  veteri- 
nary medicine,  and  the  means  of  prevention  of  disease. 
Nothing  is  said  of  treatment,  as  the  book  is  not  intended 
to  be  a  treatise  on  veterinary  medicine,  but  is  rather 


adapted  to  the  wants  of  the  hygienist  and  of  all  those 
interested  in  the  subject  of  preventive  medicine.  The 
author  is  very  dogmatic  in  his  assertions,  and  is  apt  at 
times  to  be  rather  severe  in  his  strictures  on  some  of  his 
co-laborers  in  the  same  field ;  but  this  is  a  fault,  if  fault 
it  be,  common  to  all  pioneers  in  a  new  subject  who  are 
thoroughly  in  earnest  and  who  are  of  necessity,  as  the 
author  confesses  himself  to  be,  enthusiasts.  The  book 
might,  we  think,  be  somewhat  condensed  with  advantage, 
for  to  the  general  reader  whose  time  for  studies  of  this 
sort  is  limited,  a  volume  of  440  octavo  pages  is  a  little 
formidable. 

Brain  Exhaustion,  with  some  Preliminary  Considera- 
tions on  Cerebral  Dynamics.  By  J.  Leonard  Corn- 
ing, M.D.  New  York :  D.  Appleton  &  Company. 
1884. 
In  these  days  of  hurry  and  worry  the  questions  considered 
in  the  book  before  us  have  assumed  a  measure  of  im- 
portance unknown  to  our  fathers.  We  perhaps  work  no 
harder,  but  we  work  more  irre^larly  and  with  less  re- 
gard for  the  necessity  of  relaxation,  than  those  before  us 
did.  The  demands  upon  our  thinking  apparatus  are 
very  great,  but  we  take  little  care  to  see  that  the  ap- 
paratus is  kept  in  |;ood  working  order.  But  the  time 
comes  when  the  brain  refuses  to  work  at  such  high  press- 
ure, and  if  then  it  is  urged  on  beyond  its  strength  it 
either  stops  or  breaks  away  from  all  control.  In  this 
work  on  the  exhaustion  of  the  brain,  the  author  presents, 
in  a  very  clear  and  intelligent  form,  the  various  causes 
and  symptoms  of  the  complaint,  and  points  out  the  prin- 
ciples upon  which  its  treatment  should  be  pursued.  He 
insists  very  strongly  upon  the  damage  to  the  mental  fac- 
ulties resulting  from  the  custom  of  late  and  protracted 
evening  amusements  and  the  loss  of  sleep  entailed  there- 
by. He  also  urges  the  necessity  of  a  meat  dietary  for 
brain-workers,  and  shows  very  clearly  the  mental  superi- 
ority of  meat-eaters  over  vegetarians.  The  subject  of 
the  book  is  indeed  worthy  of  careful  consideration,  and 
it  is  presented  by  the  author  in  such  a  pleasant  and 
attractive  style  Uiat  the  reader  will  find  himself  enter- 
tained as  well  as  instructed. 


WAS    HUMAN    FLESH     EATEN    BY    ANY    OF 
THE    GREELY   PARTY? 

To  THX  EdTTOB  op  Tm  MSDICAI.  Rbookdw 

Sir:  I  address  this  note  with  a  view  of  possibly  ob- 
taining some  more  definite  information  concerning  the 
microscopical  examination  of  the  contents  of  the  stomach 
of  Lieut  Kislingbury,  and  of  the  other  Arctic  dead. 
According  to  the  reports  of  the  physicians,  pieces  of  epi- 
dermis, etc.,  removed  from  the  stomach  and  intestines, 
were  recognized  as  unquestionably  human. 

I  presume  that  the  eaten  flesh  was  subjected  to  some 
mode  of  preparation  before  mastication ;  it  is  also  cer- 
tain that  the  digestive  process  must  still  further  have 
changed  the  tissues,  and  that,  in  spite  of  the  general  pres- 
ervation, a  certain  amount  of  disintegration  and  probably 
decomposition  must  have  followed. 

Was  it  possible  to  make  such  a  microscopical  examin- 
ation as  would  justify  the  unequivocal  deduction,  from 
this  alone,  that  the  ''chyme  mass  "  was  of  human  origin  ? 
Or  was  the  conclusion  a  partial  inference  from  the  con- 
dition of  the  body  and  the  reports  of  the  survivors,  which 
leave  no  doubt  in  the  mind  of  any  of  us  as  to  the  sad  oc- 
currence of  cannibalism  ? 

In  the  interest  of  "expert"  testimony,  and  exact 
science,  the  latter  of  which  so  often  unjustly  suffers  ob- 
loquy from  the  former,  can  our  colleagues,  on  the  basis 
in  question,  leave  their  conclusions  unqualified,  that  the 
stomach  contents  were  undoubtedly  human  ? 
I  am  yours  truly, 

H.  N.  Heineman,  M»D. 

49WBST  Firrv-SBysMTH  Stkbbt, 
August  19,  Z884. 


August  23,  X884.] 


THE   MEDICAL  RECORD. 


217 


(Sm:vtsvan&enct. 


THE  ANNUAL  MEETING  OF  THE  BRITISH 
MEDICAL  ASSOCIATION,  AT  BELFAST,  IRE- 
LAND 

(From  our  Special  Correspondaat.) 

Bblpast,  August  a,  1884. 

The  Belfast  meeting  may  be  pronounced  a  success.  A 
Urge  number  were  present,  and  the  general  and  sec- 
tional meetings  were  well  attended.  Belfiast  is  a  large 
town,  and  possesses  ample  acconunodation  for  a  crowd 
of  visitors.  The  building  in  which  the  meetings  were 
held — Queen's  College — ^is  one  particularly  well  adapted 
for  the  purpose  to  which  it  has  been  devoted  during 
this  week,  and  the  college  grounds,  together  with 
the  adjoining  botanical  gardens,  formed  ji  pleasant  re- 
sort  for  members  in  the  intervals  between  the  meetings. 
The  only  disadvantage  has  been  in  the  location  of  the 
college,  viz.,  between  one  and  two  miles  from  the  chief 
hotels.  Some  could  get  accommodation  near  the  place 
of  meeting,  but  this  was  necessarily  limited,  and  the  ma- 
jority of  those  present  had  to  seek  quarters  in  the  centre 
of  the  town.  To  get  to  the  meetings,  therefore,  they 
either  had  to  walk,  ride  by  tram,  or  take  an  Irish  car  or 
other  vehicle. 

The  number  of  members  of  the  Association  present 
has  been  about  five  hundred  odd,  and  if  to  this  be  added 
the  medical  visitors  and  delegates,  and  the  medical  stu- 
dents of  Queen's  College  f  who  were  permitted  to  attend), 
the  total  number  probably  exceeded  six  hundred.  A 
Dumber  of  American  physicians  were  present,  among 
them  being  Dr.  Lewis  H.  Sayre,  of  New  York ;  Dr.  John 
Shoemaker,  of  Philadelphia;  Dr.  Frederick  Hyde,  of 
Cortland  (delegate  from  the  American  Medical  Associa- 
tion), and  Dr.  A.  Jacobi,  of  New  York.  In  all,  I  think, 
some  sixteen  American  medical  men  were  present. 
From  other  distant  localities  there  also  came  representa- 
tives, viz.,  from  Guernsey,  Paris,  Geneva,  Jamaica,  and 
eren  India. 

On  the  first  day,  Tuesday,  members  began  early  to  as- 
semble, register  their  names  and  addresses,  get  their 
tickets,  and  ask  for  letters  and  telegrams  at  the  temporary 
post-office  erected  in  the  porter's  lo^e  at  Queen's  Col- 
lege for  the  convenience  of  members  during  the  meeting. 
The  latter,  as  in  previous  meetings,  proved  a  very  great 
convenience  to  members  and  others  present,  and  the 
post-office  official  placed  in  qharge  of  it  had  indeed  a 
veiy  busy  time.  Some  little  hitch  occurred  at  first  in  the 
arrangements  for  the  registration  of  members,  owing  to 
the  official  books  and  tickets  having  been  delayed  by  the 
railway  companies.  This  was  promptly  got  over  by  the 
printing  and  issuing  of  temporary  tickets,  which  were  duly 
exchanged  for  the  proper  ones  when  the  latter  arrived. 

The  proceedings  might  be  said  to  formally  commence 
with  the  first  general  meeting,  which  took  place  in  the 
library  of  Queen's  College,  and  was  well  attended.  The 
library  is  a  detached  building,  standing  in  the  college 
grounds,  and  the  large  central  hall  surrounded  by  a  gal- 
lery afforded  ample  seating  space.  This  room  was  de- 
voted to  the  general  meetings  and  to  the  Council  meet- 
ings. The  first  general  meeting  was  preceded  by  a  short 
Council  meeting,  at  which  the  following  gentlemen  were 
present :  Chairman— Mr.  C.  G.  Wheelhouse,  President  of 
tbe  Council ;  Dr.  James  Cuming,  President-elect  of  the 
Associatbn ;  Dr.  A.  T.  H.  Waters,  President ;  Dr.  T. 
Bridgwater,  Dr.  Alfred  Carter,  Dr.  Alfred  Carpenter,  Dr. 
I>cas,  Dr.  G.  F.  Duflfey,  Dr.  Balthazar  Foster,  Dr.  Grigg, 
Dr.  C.  E.  Glascott,  Dr.  Eyton  Jones,  Dr.  W.  G.  V.  Lush, 
Dr.  McVail,  Dr.  W.  Moore,  Dr.  C.  Parsons,  Dr.  Edward 
J^aters,  and  Messrs.  C.  Macnamara,  J.  Prankerd,  and  T. 
Sympson. 

At  the  Council  meeting  SS  gentlemen  were  elected 
members  of  the  Association,  and  other  business  was 
transacted. 


The  general  meeting  opened  at  3  p.m.  Dr.  A.  T.  H. 
Waters,  President,  in  die  Chair.  He  proposed  that  the 
minutes  of  the  last  meeting  should  be  taken  as  read, 
which  was  adopted  unanimously.  Dr.  Waters  made  a 
few  remarks  on  the  prosperous  state  of  the  society  and 
its  continued  increase  in  numbers.  During  the  past  year 
1,040  new  members  had  been  added  to  the  Association, 
while  only  139  members  had  died.  The  total  number 
was  now  nearly  twelve  thousand — ^to  be  exact,  he  be- 
lieved it  was  11,800. 

He  then  resigned  the  chair  to  Dr.  Cuming.  A  vote 
of  thanks  to  Dr.  Waters  was  then  proposed  by  Dr.  John 
Moore,  of  Belfast,  seconded  by  Dr.  Felce,  of  London, 
and  carried  unanimously.  Dr.  Waters  was  elected  a 
Vice-President  of  the  Association  for  life. 

Mr.  Wheelhouse  then  proposed  the  adoption  of  the 
report  of  the  Council  and  the  financial  statement  for 
the  year  1883.  Some  exception  was  taken  by  some  gen- 
tlemen to  the  sum  of  £1,660  put  down  as  paid  to  con- 
tributors to  the /ourna/f  and  it  was  asked  for  what  was 
this  sum  paid.  It  was  remarked  that  most  of  the  original 
contributions  were  offered  gratuitously  to  the /ournai,  and 
asked  whether  this  amount  was  paid  for  editorial  matter? 
It  was  explained  that  it  was  paid  for  scientific  reports 
and  various  matter  furnished  not  by  the  editor  or  his  as- 
sistants, but  by  various  gentlemen  all  over  the  country. 
Details  could  not  be  furnished  of  the  individual  articles 
for  which  payment  was  made,  but  they  were  such  as 
were  approved  by  Mr.  Ernest  Hart  in  his  editorial  ca- 
pacity, and  by  the  Journal  Committee.  The  financial 
statement  submitted  showed  that  the  total  editorial  ex- 
penses were  ;^3,ooo  odd,  yearly.  The  financial  state- 
ment and  the  report  of  the  Council  were  adopted. 

Mr.  Macnamara,  of  London,  was  then  proposed  by 
Mr.  Wheelhouse,  of  Leeds,  as  Treasurer  of  the  Association 
for  the  ensuing  three  years,  in  the  place  of  Dr.  Wade, 
whose  term  of  office  had  expired.      The  motion   was 
made  by  Dr.  Rogers  and   supported   by   Dr.  Edward 
Waters,  and  carried  unanimously.    A  letter  was  read 
firom  the  late  Treasurer  suggesting  improvements  in  the 
mode  of  signing  cheques.     Dr.  Wade  thought  there  ought 
to  be  an  additional  signature  before  moneys  were  paid 
away.      The   letter  was  referred  to    the  Council    for 
consideration.      A  motion  to  that  end  by  Dr.  Ward 
Cousins  was  passed,  and  then  a  motion  was  made  by 
Dr.  McVail  (in  the  absence  of  Mr.  Dix)  providing  for  the 
payment  out  of  the  general  funds  of  the  Association  of 
the  travelling  expenses  of  the  members  of  the  Council  to 
and  from  the  Council  meetings.     Under  the  new  con- 
stitution of  the  Association,  as  amended  last  year,  the 
Council  is  now  to  be  a  body  representative  of  the  As- 
sociation at  laj^e,  each  branch  electing  its  own  repre- 
sentative.    Dr.  McVail  urged  that  it  was  desirable  that 
the  members  of  the  Council  should  attend,  and  to  insure 
the  distant  members  doing  so,  their  expenses  should  be 
paid.     It  had  been  objected  that  it  was  unnecessary,  and 
that  there   were  in   every  branch  men  of  means  and 
leisure  who  could  attend;  but  Dr.  McVail  contended 
that  these  were  not  the  men  that  were  wanted,  but  they 
wanted  representatives  of  the  rank  and  file  of  the  pro- 
fession.    It  had  been  urged  that  distant  branches  might 
nominate  metropolitan  members  to  represent  them,  but 
this  defeated  the  very  object  of  having  a  representative 
Council.    After  prolonged  discussion  and  speeches  by  Dr. 
Alfred    Carpenter,   Mr.    George    Brown,    Dr.    Bernard 
O'Connor,   Dr.  Balthazar  Foster,  Mr.  Brindley  James, 
Mr.  Ernest  Hart,  and  others,  the  motion  was  finally  nega- 
tived,  as  it  was  when  brought  forward  at  the  Liverpool 
meeting  last  year.     Some  angry  feeling  was  exhibited  in 
the  course  of  the  discussion.     Several  speakers  main- 
tained that  the  provincial  members  did  not  attend  well, 
and  could  not  be  expected  to,  if  they  not  only  had  to 
neglect  their  practice  but  pay  their  own  expenses.     It 
was  alleged  that  the  management  was  practically  in  the 
hands  of  the  metropolitan  members.     At  some  meetings 
it  was  stated  that  a  very  large  proportion  of  those  present 


2l8 


THE   MEDICAL  RECORD. 


[August  23. 1884. 


were  metropolitan  members,  owing  to  non-attendance  of 
provincial  members.  Mr.  George  Brown  quoted  figares 
from  the  British  Medical  Journal  in  support  of  this  view, 
and  energetically  exclaimed  that  **  the  members  of  the 
Council  were  dummies."  Mr.  Hart  maintained  that  the 
average  attendance  of  the  country  members  as  compared 
with  the  metropolitan  was  very  good.  One  gentleman 
exclaimed  that  "those  were  the  dummies  who  did  not 
come." 

The  meeting  then  adjourned  for  dinner,  and  reassembled 
in  the  library  at  eight  o'clock.  The  building  was  il- 
luminated with  the  electric  light  generated  by  an  engine 
temporarily  erected  for  the  purpose. 

On  assuming  the  chair  Dr.  Cuming  delivered  his  pres- 
idential address,  which  you  have  already  published,  and 
which  was  warmly  received,  and  the  usual  vote  of  thanks 
was  then  passed. 

Lengthy  discussion  then  took  place  on  motions  brought 
forward  by  Dr.  Bernard  O'Connor,  which  were  successively 
negatived.  The  motions  were  to  the  effect  of  permitting 
members  of  branches  to  elect  members  to  represent 
them  who  did  not  necessarily  reside  within  the  area  of  the 
branch,  so  that  distant  branches  could  be  represented 
by  members  who  resided  near  London.  The  last  motion 
fell  through  for  want  of  a  seconder. 

A  somewhat  disorderly  scene  then  took  place  in  con- 
nection  with  a  motion  brought  forward  by  Mr.  George 
Brown.  He  was  finally  declared  out  of  order,  and  the 
meeting  terminated  between  ten  and  eleven  o'clock. 

At  the  second  general  meeting  on  Wednesday,  at  eleven, 
it  was  reported  that  Dr.  Balthazar  Foster  had  been 
elected  President  of  the  Council  for  the  ensuing  three 
years.  A  vote  of  thanks  was  passed  to  Mr.  Wheelhouse 
for  'his  past  services  in  the  same  capacity.  It  was  an- 
nounced that  Cardiff  had  given  an  invitation  to  hold  the 
next  annual  meeting  in  1885  in  that  town,  and  this  was 
unanimously  accepted,  and  Dr.  W.  T.  £dwards,  senior 
physician  to  the  Glamorganshire  and  Monmouthshire 
Infirmary,  chosen  President-elect.  Dr.  £dwards  re- 
turned thanks.  Dr.  Ord  then  delivered  the  Address  in 
Medicine  (which  we  publish  in  our  present  number).  A 
vote  of  thanks  to  Dr.  Ord  was  then  proposed  by  Dr.  A.  T. 
H.  Waters,  of  Liverpool.  He  was  sure  they  would  all 
agree  with  him  that  the  address  had  been  a  very  able  and 
interesting  one.  Dr.  Ord  had  travelled  over  a  wide  field, 
and  had  treated  his  subject  with  great  success.  The  im- 
portant relations  of  reflex  action  in  the  human  system 
had  long  occupied  their  attention,  but  he  thought 
Dr.  Ord  had  placed  before  them  more  forcibly  perhaps 
than  it  had  been  done  before  the  important  influence 
of  the  nervous  system  in  the  production  of  chronic 
rheumatoid  arthritis.  He  (the  speaker)  had  seen  cases 
of  this  disease  in  elderly  people,  which  he  felt  fully  con- 
vinced must  be  traced  to  neurotic  origin.  He  would 
only  remark  that  the  influence  of  the  nervous  system  on 
the  production  of  disease  no  doubt  required  very  deep, 
careful,  and  profound  study  ;  and  perhaps  the  lines  of 
thought  which  they  had  had  laid  down  by  Dr.  Ord  would 
give  them  much  material  for  reflection.  He  thought 
an  address  of  that  kind  was  not  only  eminently  scien- 
tific but  essentially  practical. 

Professor  Gairdner,  of  Glasgow,  seconded  the  resolu- 
tion. He  came  there  very  early  that  morning  in  order 
to  obtain  a  good  place  to  hear  Dr.  Ord,  but  when  the 
President  of  the  Council  pounced  upon  him  at  once  with 
an  offer  of  the  duty  he  was  then  performing,  he  felt  in  the 
position,  not  of  the  early  bird  that  caught  the  early  worm, 
but  of  the  early  worm  snapped  up  by  that  watchful  and 
ever  wary  bird  the  President.  He  could  say  that,  hav- 
ing followed  the  course  of  Dr.  Ord's  investigation,  he  had 
never  read  a  page,  word,  or  line  of  his  writing  which  did 
not  bear  the  mark  of  something  to  be  very  carefully  and 
deliberately  thought  over.  Under  those  circumstances, 
it  would  be  a  very  poor  compliment  to  Dr.  Ord  to  there 
enter  into  anything  like  a  discussion  upon  the  address 
they  had   heard.     As  a  teacher  of  medicine,  he  (the 


speaker)  was  compelled  by  his  office,  as  it  were,  to  study 
systematically  the  turns  and  currents  of  opinion,  and  it 
was  extremely  interesting  to  him  to  note,  and  to  accen- 
tuate the  fact,  that  the  drift  marked  by  such  addresses  as 
that  to  which  they  had  listened  was  decidedly  in  favor  of 
solidism.  All  he  could  say  there  then  was  that  Dr.  Ord 
had  made  a  most  powerful  pleading  in  favor  of  the  neu- 
rotic ori^n  of  disease,  which  they  had  been  in  the  habit 
of  ascribing  to  other  sources.  They  were  all  insensibly 
biassed  by  the  systematic  views  which  they  took  of  things, 
but  they  must  admit  that  the  facts  of  science  were  too 
complex  for  them,  and  would  bear  looking  at  from  many 
points  of  view. 

The  motion  was  carried  by  acclamation. 

Dr.  Ord  having  acknowledged  the  vote  in  a  few  words, 
the  new  Council  for  1884-85  was  announced,  and  the 
Association  adjourned. 

In  the  evening  a  conversazione  was  given  in  Queen's 
College  by  the  President  of  the  Association  and  the  Ex- 
ecutive Committee.  In  spite  of  the  unfavorable  weather 
— it  raining  heavily  during  the  evening — this  was  very  nu- 
merously  attended.  To  this  ladies  were  admitted.  The 
college  was  brilliantly  illuminated  by  the  electric  light, 
and  presented  a  festive  appearance.  The  rooms  were 
crowded  to  overflowing. 

At  the  third  general  meeting  Dr.  Redfem  delivered 
his  address.  At  the  fourth  general  meeting  Dr.  Kidd 
delivered  his  address  on  '<  Obstetrics,"  which  was  cordi- 
ally received  and  the  usual  vote  of  thanks  given. 

At  two  o'clock  the  concluding  general  meeting  was 
held  in  the  library,  when  the  discussion  on  medical  re- 
form was  continued  by  various  gentlemen,  and  the  reports 
of  the  Parliamentary' Bills  Committee,  Habitual  Drunk- 
ards Committee,  Scientific  Grants  Committee,  and  the 
Collective  Investigation  Committee. 

In  the  evening  a  reception  by  the  Mayor  in  the  Ubter 
Hall  was  numerously  attended. 

SECTIONS. 

Section  on  Surgery. — Sir  W.  MacCormac  delivered 
the  address  m  the  Section  on  Surgery,  and  spoke  of  the 
advances  in  visceral  surgery — cerebral,  thoracic,  ab- 
dominal— and  also  of  gastrostomy,  the  early  history  of 
which  was  disastrous,  but  which  he  now  considered  justi- 
fiable, and  referred  to  two  recent  cases  of  malignant  dis- 
ease in  which  he  hftd  performed  the  operation  with  con- 
siderable benefit  to  the  patient  and  prolongation  of  life. 
He  recommended  the  operation  to  be  performed  early 
enough  in  such  cases,  and  considered  antiseptics  gave  a 
good  chance.  He  spoke  of  Howse's  plan,  of  dividing 
the  operation  into  two  parts,  as  removing  practically  all 
risk.  He  then  spoke  of  the  radical  cure  of  hernia,  but 
preferred  the  term  radical  treatment.  He  said  the  opera- 
tion was  not  new  but  old ;  it  was  easily  done  in  that  for 
strangulated  hernia  as  a  step  in  the  operation.  This  was 
a  great  advantage,  and  he  thought  in  strangulated  hernia 
the  radical  treatment,  by  excising  a  portion  of  the  sac, 
should  always  be  done.  In  congenital  inguinal  hernia 
he  believed  a  radical  cure  could  be  effected.  He  then 
referred  to  the  operation  of  thyroidotomy.  It  was  one  of 
the  most  formidable  and  difficult  operations  in  surgery. 
Its  dangers  were  mainly  two,  viz.,  sepsis  and  bleeding. 
To  avoid  the  latter  he  suggested  the  ligature  of  the 
vessels  first.  He  questioned  Kocher's  views  as  to  the 
liability  to  myxcedema  and  cretinism  as  a  sequel  of 
removal  of  the  gland  ;  but  he  said  that  neither  of  these 
results  had  ever  followed  partial  removal  of  the  gland, 
and  in  many  cases  this  was  sufficient.  He  spoke  favor- 
ably of  the  operation  of  ligature  of  the  isthmus  of  the 
thyroid  in  some  cases. 

On  Wednesday  morning  at  9.30  Dr.  Sayre  gave  a 
special  demonstration  of  the  application  of  plaster  jackets 
by  his  method  on  some  living  patients.  After  MacCor- 
mac addressed  there  was  a  discussion  on  the  treatment 
of  spinal  curvatures,  introduced  by  Dr.  Sayre. 

Speeches  by  Messrs.  Bernard  Roth,  C.  B.  Keetley,  E. 


August  23,  1884.] 


THE  MEDICAL   RECORD. 


219 


Freer,  and  others.     Dr.  Sayre  replied  and  defended  his 
views.    He  opposed  the   application   of  heavy  metal 
splints  and  apparatus.     He  showed  a  little  apparatus, 
consisting  of  some  vertebrae  strung  on  a  wire  so  as  to 
represent  a  curved  spinal  column,  and  showed  that  any 
force  applied  to  the  vertebras,  so  long  as  each  end  of  the 
column  remained  fixed,  merely  altered  the  position  of  the 
distortion,  but  did  not  remove  it,  while  extension  did  so 
at  once.     He  referred  to  cases  in  which  the  application 
of  his  apparatus  had  been  followed  by  immediate  benefit^ 
and  mentioned  a  case  in  which  a  patient  had  left  the 
hospital  and  resumed  hard  labor  soon  after  treatment  by 
this  method.     Referring  to  different  apparatuses,  he  said 
he  had  two  wagon  loads  of  them  at  home.     He  con- 
sidered plaster  superior  to  felt     Dr.  Sayre  was  very  well 
received,  and  his  remarks  greeted  with  loud  applause. 
Perhaps  the  largest  audience  in  any  section  was   that 
which  assembled  to  hear  Sir  William  MacCormac's  ad- 
dress, and  the  subsequent  debate  on  the  plaster  jacket. 
Dr.  Sayre  repeated  his  demonstration  on  Friday  morning. 
Section  on  Medicine. — In  the  discussion  on  albumi- 
nuria Dr.  George  Johnson  opened  it,  and  defended  his 
theory.     He  considered  the  limited  area  of  the  changes 
in  the  walls  of  the  arteries  was  an  objection  to  the  theory 
of  morbid  blood.     Speaking  more  particularly  as  to  treat- 
ment, he  said  exclusive  mUk  diet  was  often  good  in  re- 
cent cases.     He  had  known  a  patient  of  robust  frame 
subsist  forfyears  on  about  a  gallon  of  skimmed  milk  daily, 
and  nothing  else,  except  when  travelling  and  unable  to 
obtain  the  milk.     He  demonstrated  the  picric-acid  tests 
for  sugar  and  albumen,  seven  grains  in  one  ounce  of  boil- 
ing water  gave  a  saturated  solution.     He  said  in  testing 
by  this^method  never  omit  to  boil,  because  picric  acid 
may  precipitate  urates,  which  are  dissolved  on  the  ap- 
plication of  heat.     He  said  he  considered  the  only  test 
for  albumen    equal    to    the   picric-acid   tests  was  the 
potassio-mercuric  iodide  test  with  citric  acid,  and  this 
was  complicated.     He  then  demonstrated  the  picric  acid 
test  for  sugar. 

One  of  the  secretaries  then  read  a  letter  on  the 
subject  from  Sir  Andrew  Clark,  Bart.,  who  said  that  there 
was  a  non-renal  form  of  albuminuria  which  it  was  im- 
portant to  disrin^ish  from  renal.  He  said  this  was 
sometimes  met  with  for  a  few  days  before  and  after  each 
menstrual  period ;  also  from  albumen  from  vaginal  and 
other  secretions,  bladder  tumors,  etc.,  in  women  ad- 
dicted to  impure  habits.  He  spoke  of  functional  albu- 
minuria, and  described  four  forms,  viz.  :  nervous  and  ox- 
aluric,  mostly  in  the  young ;  hepatic  and  gouty,  mostly  in 
the  old.  These  were  worthy  of  especial  study.  He  said 
he  bad  known  albuminuria  come  on,  after  a  competitive 
examination  in  three  out  of  twenty  candidates.  He  had 
known  temporary  albuminuria  in  a  gouty  man  after  at- 
tending a  public  meeting.  He  remarked  that  oxaluria, 
high  tension  in  the  blood-vessels,  and  excess  of  urea,  were 
followed  mostly  before  long  by  albuminuria.  He  spoke 
of  the  importance  of  study  of  the  causes. 

On  Thursday  afternoon  a  discussion  took  place  on  the 
•* Causes  of  Phthisis,"  introduced  by  Dr.  Douglas  Powell, 
of  London,  who  said  that  he  doubted  much  the  contagious- 
ness of  phthisis.  He  remarked  that  many  so-called  cases 
of  contagion  were  very  strange.  A  phthisical  man  marries 
three  wives,  who  all  die  of  the  disease,  while  he  continues 
to  live.  How  is  it  that  while  evolving  sufficient  of  the 
poison  to  kill  all  three  wives,  it  is  not  present  in  his  body 
in  sufficient  intensity  to  kill  him  ?  He  considered  that 
it  often  began  with  inflammation  at  the  apex  of  one  lung. 
He  remarked  that  if  we  could  cremate  all  the  bacilli  we 
should  still  have  phthisis  left,  and  other  bacilli  would  be 
evolved  in  time. 

Dr.  Ward  Cousins,  of  Portsmouth,  made  a  very 
spirited  and  energetic  speech.  He  said  he  did  not  be- 
lieve in  antiseptic  inhalations  destroying  the  bacilli.  We 
could  not  use  sufficiently  powerful  antiseptics  to  destroy 
bacilli  embedded  in  the  substance  of  the  lung.  He  pro- 
tested against  covering  up  the  mouth  and  nose  with  in-  i 


"halers  to  keep  out  the  bacilli  which  were  in  the  atmos- 
phere. What  was  the  use  of  that  when  they  were  already 
in  the  lung  ?  He  remarked  that  the  lower  classes  were 
particularly  averse  to  a  breath  of  fresh  air  coming  near 
them,  especially  such  as  were  suffering  from  chest  dis- 
eases. The  theory  of  Koch  had  given  an  immense  im- 
petus to  the  practice  of  antiseptic  inhalations.  Dr. 
Cousins  employs  inhalations  in  many  cases  of  chest  dis- 
ease, but  he  advocated  open  inhalation.  He  remarked 
that  he  believed  that  free  expectoration  was  very  desira- 
ble in  cases  of  phthisis.  Referring  to  the  late  Dr.  Ram- 
adge,  he  said  Dr.  Ramadge  was  laughed  at  in  his  day. 
Dr.  Ramadge  invented  a  whistle  for  his  patients  to  use. 
But  Dr.  R.  was  quite  right  in  his  theory.  It  was  of 
the  utmost  importance  to  keep  at  work,  and  inflated  with 
air,  that  portion  of  the  lung  which  was  not  yet  attacked 
by  the  disease.  Dr.  Cousins  referred  to  different  inhalers, 
and  after  speaking  of  some  which  were  heavy,  said  one 
had  been  brought  out  which  only  weighed  three  drachms. 
He  then  showed  his  own,  which  he  said  only  weighed  one 
drachm  twelve  grains.  He  had  nasal  inhalers  to  wear  on 
either  nostril,  changing  from  one  to  the  other  when  you 
pleased.  He  had  also  a  little  inhaler  for  the  mouth,  to 
hold  in  either  corner,  and  remarked  that  you  could  go 
on  talking  with  it  in.  He  created  great  amusement  by 
continuing  his  speech  with  the  oral  inhaler  first  in  one 
comer  of  his  mouth  and  then  in  the  other. 

Professor  Gairdner  of  Edinburgh  referred  to  the  views 
of  Dr.  MacCormac,  of  Belfast,  who  held  that  the  cause 
of  phthisis  was  breathing  and  rebreathing  the  same  air. 
He  could  not  subscribe  to  Dr.  MacCormac's  views  in 
their  entirety,  nor  could  any  one,  he  thought,  in  the 
present  state  of  pathology.  He  could  not  believe  that 
rebreathed  air  in  itself  produced  phthisis.  He  referred 
to  miners'  lung  and  other  conditions  caused  by  air  laden 
with  foreign  matter — these  were  not  phthisis.  He,  how- 
ever, believed  impure  air  to  be  an  important  condition  in 
the  causation  of  phthisis,  even  more  so  than  exposure  to 
cold,  wind,  or  damp.  He  supported  Koch  in  his  views. 
He  also  believed  in  the  transmission  of  phthisis  heredi- 
tarily, but  he  did  not  see  how  this  could  take  place  by 
means  of  bacilli.  He  could  not  conceive  of  bacilli  being 
given  off  in  the  semen  or  finding  their  way  into  the 
ovum. 

In  the  Section  on  Public  Health,  on  Wednesday,  Dr, 
Barthe  de  Standfort,  of  Dax,  read  a  paper  in  French,  on 
the  "  Disinfection  of  Ships  after  Infective  Diseases,"  in 
which  he  maintained  it  was  impossible  to  thoroughly  dis- 
infect a  vessel  in  the  number  of  days  allowed  for  quaran- 
tine. He  believed  the  best  disinfectant  to  be  sulphur- 
ous acid,  which  had  been  recommended  to  the  United 
States  Government,  but  not  adopted  on  account  of 
its  cost  He  held  that  an  infected  vessel  should  be 
thoroughly  washed,  then  fumigated  for  twenty-four  hours, 
and  afterward  subjected  to  very  complete  ventilation  for 
four  or  five  days. 

He  was  well  received,  and  at  a  later  stage  warmly 
thanked  his  audience,  and  said  he  should  carry  back  to 
France  a  lively  recollection  of  his  kindly  reception  in 
Belfast. 

Mr.  Kirker,  R.N.,  read  a  paper  on  **The  Cholera 
Epidemic  in  E^ypt,  1883,"  in  which  he  said  there  were 
only  8  victims  m  Port  Said,  a  filthy  town  of  17,000  in- 
habitants, and  thought  that  Koch  had  not  sufficient  war- 
rant for  predicting  that  the  disease  would  spread  from 
Toulon  all  over  Europe.  He  believed  that  the  British 
Isles  would  this  year  escape,  chiefly  on  account  of  re- 
cent changes  in  the  weather,  with  its  rain  and  brisk 
breezes.  He  regarded  a  hot,  stifling,  stagnant  condition 
of  the  air  as  the  great  danger,  but  while  purifying  winds 
lasted  he  would  say,  **  Fear  not  the  cholera  of  Toulon 
and  Marseilles."  It  was  more  important  to  find  out  the 
conditions  of  life  of  the  individual  in  his  home  than  to 
look  for  germs. 

Dr.  Cullimore,  of  London,  in  a  paper  on  "Quaran- 
tine," said  that  people  would  prefer  the  risk  of  cholera 


220 


THE  MEDICAL  RECORD. 


[August  23,  1884, 


to  the  rigid  application  of  quarantine,  which  was  not 
likely  to  be  carried  out  successfully  for  any  length  of 
time.  Quarantine  by  sea  could  be  defended  by  argu- 
ments inapplicable  to  sanitary  cordons  and  other  at- 
tempts at  isolation  on  land.  A  well-managed  ship  at 
sea  lying  off  a  port  afforded  the  opportunity  of  stamping 
out  a  disease  which  was  never  offered  on  land. 

Dr.  Davies,  Medical  Officer  of  Health  for  Bristol,  con- 
demned compulsory  notification,  which  he  found  quite 
unnecessary  in  his  district  of  220,000  inhabitants.  He 
had  seen  as  much  cholera  as  most  practitioners  for  in 
the  first  epidemic  2,000  died  in  Bristol.  When  threat- 
ened they  put  their  drains  under  disinfection  with  large 
quantities  of  sulphate  of  iron.  Ships  were  entering  the 
port  from  Marseilles  and  cases  might  be  brought  in,  but 
he  defied  them  to  spread.  He  did  not  much  believe  in 
gaseous  disinfectants. 

Dr.  Cameron,  M.P.,  Medical  Officer  of  Health  for 
Dublin,  and  President  of  the  Section,  said  he  did  not  be- 
lieve in  land  quarantine,  but  he  did  in  a  well-established 
naval  quarantine.  He  was  in  favor  of  washing  the  inte- 
rior of  infected  dwellings  with  soap  and  water.  He  found 
dry  chlorine  and  sulphurous  acid  would  not  kill  bacteria 
but  solutions  would. 

Dr.  Grimshaw,  Registrar- General  for  Ireland,  spoke  in 
favor  of  the  notification  of  diseases,  and  though  the  re- 
sults had  not  up  to  the  present  time  been  favorable,  he 
thought  that  was  because  the  notification  had  only  been 
carried  out  partially.  To  be  effective  it  would  require 
to  be  reciprocal  between  the  various  districts,  and  even 
through  the  country  at  large. 

THE   MUSEUM. 

The  annual  exhibition  of  objects  of  interest  in  connec- 
tion with  medicine,  surgery,  and  the  allied  sciences,  took 
place  in  the  Exhibition  Hall,  Botanic  Gardens,  and  in 
the  Queen's  College.  Subsection  A. — i.  Preparations, 
diagrams,  casts  and  models  of  anatomical  and  pathologi- 
cal objects,  microscopes  and  microscopic  preparations. 
Subsection  B. — 2.  Surgical  and  medical  instruments  and 
appliances,  thermometers,  and  other  instruments  for 
scientific  investigation.  Subsection  C. — 3.  Foods,  drugs, 
chemicals,  and  pharmaceutical  preparations.  Literary 
and  Sanitary  Subsection  D, — 4.  New  medical  books.  5. 
Ambulances,  carriages,  and  other  means  of  locomotion  for 
the  use  of  medical  practitioners.  6.  Sanitarv  appliances, 
including  drawings,  models,  and  apparatus,  illustrative  of 
the  ventilation  of  hospitals,  public  buildings,  and  private 
dwellings.  7.  Plans  and  models  of  hospitals,  public 
buildings,  and  private  dwellings,  constructed  upon  the 
most  improved  hygienic  principles.  8.  Recent  improve- 
ments in  hospital  furniture. 

In  the  Pathological  Section  I  noticed  more  particularly 
the  following  among  many  other  objects.  Sketch  of 
elephantiasis  labii  and  plaster  cast  of  the  tumor — removed 
by  Mr.  Fagan,  of  Belfast.  Specimen  of  male  gen- 
erative  organs,  showing  operation  of  cleft  urethra  as 
practised  among  the  aborigines  of  West  Australia — Dr. 
W.  Whitle,  Belfast.  Ruptured  intestine  caused  by  crush 
without  external  injury — Dr.  James  Barrow,  Belfast. 
Recent  Colles'  fracture,  third  day — Dr.  James  Barrow, 
Belfast.  Several  specimens  (about  forty)  of  Colles'  frac- 
ture— from  Queen's  College  Museum.  Bread-cart  frac- 
ture of  tibia  and  fibula — Dr.  James  Barrow,  Belfast. 
Colored  drawings  of  skin  diseases — Dr.  C.  F.  Moore, 
Dublin.  Ten  jelly  preparations  of  eyes,  showing  various 
diseased  conditions — Mr.  Juler,  London.  Thirty  eye 
preparations — Mr.  A.  Hill  Griffitlis,  Manchester. 

In  the  Surgical  Instrument  Department  there  were  ex- 
hibits by  many  of  the  leading  firms.  Messrs.  Steel  & 
Sons,  of  Belfast,  showed  specimens  of  surgical  and  other 
instruments  plated  by  them.  Dr.  C.  Godson  exhibited 
a  thermostatic  nurse  for  the  bringing  up  of  prematurely 
born  infants,  and  a  four-bladed  perforator.  He  gave  a 
demonstration  (on  the  foetus)  of  the  latter  on  Friday, 
August  I  St.     Messrs.  Wilson  &  Son,  of  Harrogate,  ex- 


hibited Dr.  Oliver's  urinary  test-papers.  Among  them 
was  a  new  cupric  test-paper  for  sugar.  A  paper  is  boiled 
in  a  drachm  of  water  for  a  few  seconds,  then  removed, 
the  solution  reboiled,  and  one  drop  of  the  suspected 
sugar  added,  when,  if  any  be  present  a  yellowish  opacity 
appears  throughout  the  fluid. 

SPECIAL   MEETINGS. 

Medical  Sickness^  Annuity,  and  Life  Assurance  Society, 
—The  First  Annual  Meeting  of  the  Medical  Sickness,  An- 
nuity, and  Life  Assurance  Society  was  held  in  the  Greek 
Lecture  Room,  Queen's  College,  on  Thursday,  July  31st, 
at  12.30  in  the  afternoon. 

New  Sydenham  Society. --TYit  Annual  Meeting  of  the 
Society  was  held  on  Thursday,  July  3TSt,at  9.30  o'clock, 
in  the  Greek  Lecture  Room,  Queen's  College— Sir  W. 
MacCormac  in  the  Chair. 

Poor  Law  Medical  Officer^ Association, — ^The  Annual 
Meeting  of  the  Association  was  held  on  Wednesday,  July 
30th,  in  the  Greek  Lecture  Room,  at  i  o'clock  in  the 
afternoon.  Dr.  Joseph  Rogers,  of  London,  Chairman 
of  Council,  presided. 

Irish  Graduated  Association.--The  Annual  Meeting 
of  the  Association  was  held  on  Wednesday,  July  30th,  at 
5  P.M.,  in  the  Library,  Queen's  College.  The  President 
of  the  Irish  Graduates'  Association,  Professor  G.  F.  Yeo, 
M.D.,  was  in  the  Chair. 

Meeting  of  Members  of  the  Royal  College  of  Surgeons, 
—A  Meetingof  Members  of  the  Royal  College  of  Surgeons 
was  held  in  the  Greek  Lecture  Room,  on  Thursday,  July 
31st,  at  5  o'clock  in  the  afternoon. 


OUR  LONDON   LETTER. 

(From  our  Special  Correspondent.) 
THE    HOLIDAY    SEASON    AND    THE    HOSPITALS — CHOLERA 
AND    PRECAUTIONS    AGAINST    IT — OUTBREAKS   OF   ENG- 
LISH   CHOLERA — THE   VOLUNTEER   AMBULANCE  CORPS. 

London,  August  9, 1884. 

The  holiday  season  may  be  said  to  have  fairly  set  in, 
and  although  Parliament  is  still  sitting,  both  doctors  and 
their  patients  are  running  off"  to  the  country  wholesale. 
At  many  of  the  hospitals  a  large  proportion  of  the  staff 
have  gone  off  for  their  holiday,  and  left  the  bulk  of  the 
work  to  be  done  by  a  few  of  their  junior  colleagues. 
At  the  larger  hospitals  August  and  September  are  pot 
by  any  means  the  worst  months  to  see  hospital  practice. 
It  is  true  that  then  most  of  the  ornamental  members  of 
the  staff  are  away,  but  so  are  the  great  majority  of  the 
students,  and  cases  can  be  examined  at  leisure  without 
the  overcrowding  met  with  during  the  session. 

No  case  of  Asiatic  cholera  has  yet  occurred  in  Great 
Britain,  although  several  false  alarms  have  been  raised. 
Any  ships  arriving  from  which  there  has  been  any  reason 
to  dread  infection  have  been  promptly  disinfected.  The 
Metropolitan  Board  of  Works  are  taking  measures  to 
deodorize  the  sewage  of  London  at  a  daily  cost  of  be- 
tween seven  and  eight  hundred  pounds.  I  understand 
that  at  present  about  thirty  tons  a  day  of  chloride  of  lime 
are  being  used,  and. three  or  four  tons  of  permanganate  of 
potash.  The  College  of  Physicians  has  issued  a  paper 
of  directions  as  to  precautions  to  be  taken  against  the 
cholera. 

Several  outbreaks  have  occurred  of  so-called  English 
cholera  in  different  parts  of  the  country,  and  some  deaths 
are  reported.  A  deficiency  in  the  water-supply  is  al- 
leged to  be  the  cause.  This  has  doubtless  led  to  the 
use  of  impure  water. 

The  Volunteer  Ambulance  Corps  got  up  amongst  the 
students  of  the  London  hospitals  has  already  attained 
some  success.  I  believe  nearly  every  one  of  ,the  eleven 
medical  schools  in  London  has  now  its  own  corps. 
Charing  Cross  Hospital  contributes  perhaps  the  largest 
number,  although  having  by  no  means  the  largest  num- 
ber of  students.     This  is  explained  when  I  state  that  the 


August  23,  1884.] 


THE  MEDICAL  RECORD. 


221 


movement  was  started  largely  through  the  efforts  of  Mr. 
Cautlie,  one  of  the  surgeons  to  that  institution.  The 
total  number  of  members  enrolled  now  reaches  nearly 
two  hundred.  I  am  afraid  that  many  of  them  have  not 
as  yet  learned  to  observe  due  discipline,  as  I  have  been 
informed  by  a  member  that,  at  some  of  the  parades 
which  have  taken  place,  about  half  of  those  in  the  ranks 
were  talking  and  laughing.  In  the  corps  of  some  hos- 
pitals too  large  a  number  of  officers  have  been  appointed, 
so  that  at  some  drills  more  officers  than  men  have  made 
their  appearance. 

One  must  not,  however,  be  too  captious,  especially 
considering  that  it  is  volunteer  work,  and  work,  too, 
rather  outside  the  area  of  ordinary  medical  studies.  It 
is  quite  as  laborious  as  cricket  or  foot-ball,  but  probably 
not  so  enjoyable.  Lifting  about  heavy  men  and  manoeu- 
vring with  heavy  stretchers,  is  by  no  means  play  in  the 
hot  weather  we  have  lately  had.  Four  bearers  carry 
each  stretcher,  but  one  of  the  movements  in  the  drill 
consists  in  transferring  the  whole  weight  to  the  shoulders 
of  one  bearer,  leaving  the  other  three  free. 

The  utility  of  the  organization  will,  it  is  thought, 
mainly  consist  in  the  fact  that,  when  its  present  members 
have  gone  through  their  hospital  career  and  are  scattered 
all  over  the  country,  each  of  them  will,  so  to  say,  form  a 
centre  whence  a  similar  movement  can  originate.  In 
remote  country  districts  each  medical  man  who  has  been 
a  member  of  the  Volunteer  Ambulance  Corps  will  be 
competent  to  start  a  local  corps,  drill  and  train  it.  The 
advantage  this  will  be,  should  we  ever  be  at  war,  is  obvi- 
ous. 


^rms  and  ^xrg  ^evas. 


OfidalListcf  ChangisiniheSiaiUms  and  Duties  cf  Ojfiars 
urving  in  tht  Medical  Department^  United  States  Army^ 
from  August  10  to  August  16,  18S4. 

Bartholf,  J.  H.,  Captain  and  Assistant  Surgeon, 
Relieved  from  duty  at  Vancouver  Barracks,  Wash.  Terr., 
and  ordered  to  take  station  at  Portland,  Ore.  S.  O.  114, 
])ar.  I,  Headquarters  Department  of  Colorado,  August  i, 
1834. 

Heizmann,  C.  L.,  Captain  and  Assistant  Surgeon. 
Ordered  to  proceed  to  Fort  Ontario,  N.  Y.,  and  report 
for  duty.  S.  O.  163,  par.  3,  Headquarters  Department 
of  the  East,  August  13,  1884. 

Kane,  John  J.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month.  S.  O.  160, 
par.  I,  Headquarters  Department  of  the  East,  August 
10,  1884. 


Medical  StjenxB. 


Oficial  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  August  16,  1884. 

BoGERT,  E.,  Medical  Inspector.  To  be  Fleet  Sur- 
geon, Asiatic  Squadron. 

Babin,  H.  J.,  Surgeon.  Detached  from  U.  S.  S.  Min- 
nesota.    Ordered  to  Marine  Rendezvous,  New  York. 

Whiting,  R.,  Passed  Assistant  Surgeon.  Detached 
from  Marine  Rendezvous,  New  York.  Ordered  to  Naval 
Academy,  as  Member  of  Examining  Board 

Cooke,  G.  H.,  Surgeon.  Ordered  to  Naval  Academy, 
as  Member  of  Examining  £oard. 

RiXEV,  P.  M.,  Passed  Assistant  Surgeon.  Detached 
from  special  duty  at  Washington.  Ordered  to  U.  S.  S. 
Lancaster. 

WooLVERTON,  T.,  Siu-geon,  Ordered  to  U.  S.  S.  Min- 
nesota. 


Contagious  Diseases — Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  August  16,  1884 : 


Week  Ending 

Ei4 

1 

£ 

l^ 

j 

j 

1 
1 

Ctues, 

Aucrust  0.  i88j. 

0 

7fi 

35' 
34 

3 
2 

7^ 

?R 

0 

0 

August  16, 1884 

2 

30 

5= 

34 

0 

0 

Deaths. 

Aucrust  0.  i88j. 

0 

7 

7 

3 

2 

^n 

I? 

n 

0 

August  16, 1884 

0 

3 

2 

7 

13 

0 

0 

Gum  Ammoniac  contains  a  small  amount  of  volatile  oil 
which  is  somewhat  irritating  to  the  skin  and  mucous 
membranes,  and  is  eliminated  through  the  bronchial  and 
perhaps  the  mucous  membranes.  It  is  chiefly  used  in 
chronic  bronchitis  and  bronchorrhoea,  but  is  far  more  use- 
ful in  mucous  and  torpid  conditions  of  the  stomach  and 
bowels  and  perhaps  urethra.  A  pill  with  one  or  two 
grains  of  aloes  and  the  same  of  ammonia  is  often  better 
than  the  aloes  and  myrrh  pill.  Some  attribute  virtues 
to  it  in  cirrhosis  of  the  liver  and  other  organs,  but 
muriate  of  ammonia  is  better. 

Hydrochloric  Ether,  or  chloride  of  ethyl,  or  muriatic 
ether,  is  almost  identical  in  its  effect  with  sulphuric  ether. 
But  it  is  so  volatile  and  inflammable  as  to  be  almost  un- 
manageable in  practice.  It  is  sometimes  put  in  Hoff- 
mann's anodyne  as  an  agreeable  substitute  for  sulphuric 
ether.  Hydrochloric  or  muriatic  ether  is  used  in  medi- 
cine in  solution,  and  is  formed  in  the  muriate  tincture 
of  iron,  where  it  is  highly  prized,  and  to  which  more 
could  be  added  to  great  advantagS. 

Hydrobromic  Ether  is  obtained  from  bromine  and 
alcohol  in  the  presence  of  phosphorus.  It  is  colorless, 
volatile,  has  a  very  strong  ethereal  odor,  and  a  warm, 
sweetish  taste.  It  bums  with  difliculty  and  is  sparingly 
soluble  in  water,  but  is  soluble  in  alcohol  and  ether.  It 
has  the  same  efiects  as  hydrochloric  ether,  and  produces 
anaesthesia  without  excitement  or  suffering.  It  has  been 
inhaled  for  sleeplessness.  It  may  be  used  in  place  of 
hydriodic  ether. 

To  OBTAIN  Hydriodic. Ether,  distill  absolute  alcohol 
and  hydriodic  acid  together,  or  alcohol,  phosphorus,  and 
iodine.  It  is  non-inflammable,  but  has  a  peculiar  pene- 
trating, powerful  ethereal  odor.  It  is  nearly  insoluble  in 
water,  but  soluble  in  alcohol.  Exposed  to  air  and  light 
it  liberates  iodine.  Dose :  ten  or  fifteen  drops  inhaled 
several  times  a  day  from  a  handkerchief  to  bring  the 
system  rapidly  under  the  influence  of  iodine  in  chronic 
bronchitis  and  consumption,  but  more  especially  in  leu- 
cocythsemia,  pernicious  anaemia,  enlargement  of  the  liver 
and  spleen. 

Acetic  Ether  is  made  from  acetate  of  sodium,  8 
parts;  rectified  spirits,  5  parts,  and  sulphuric  acid,  10 
parts ;  distilled  together.  Sulphuric  acid  is  first  formed. 
It  is  colorless,  limpid,  and  volatile,  having  an  agreeable 
refireshing  ethereal  odor,  and  is  less  inflammable  than  sul- 
phuric ether.  It  dissolves  in  all  proportions  in  alcohol  and 
ether,  also  in  eleven  or  twelve  parts  of  water.  It  dis- 
solves a  little  phosphorus  and  sulphur.  When  inhaled  it 
produces  perfect  unconsciousness,  without  as  much  pre- 
vious struggling  as  sulphuric  ether,  and  is  less  volatile. 
From  its  pungency  and  agreeable  odor,  its  stimulant  and 
anti-spasmodic  qualities,  it  is  used  for  several  of  the 


222 


THE   MEDICAL   RECORD. 


[August  23,  1884. 


minor  purposes  of  sulphuric  ether,  especially  in  syncope 
and  in  nervous  agitation.  Dose,  30  minims,  properly 
diluted  Externally,  it  may  be  applied  wherever  sulphu- 
ric ether  is  appropriate.  Its  agreeable  smell  and  almost 
equally  powerful  action  renders  it  a  good  substitute  for 
sulphuric  ether  in  Hoffmann's  anodyne,  in  the  treatment 
of  flatus  and  gastralgia,  but  especially  in  nervous  or  hys- 
terical sick-headache.  It  is  also  used  in  minor  opera- 
tions where  only  the  first  stages  of  ether  action  are 
required. 

Formic  Ether  was  discovered  by  Bucholz  in  1782. 
It  is  made  from  8  parts  formate  of  soda,  7  parts  alcohol, 
and  1 1  parts  sulphuric  acid,  which  are  distilled  together. 
It  has  a  strong  agreeable  odor,  like  peach  kernels,  but  a 
pungent  taste.  It  dissolves  in  nine  parts  of  water  and  in 
alcohol.  It  readily  undergoes  decomposition  into  alcohol 
and  alkaline  formiates  through  the  alkali  of  the  blood. 
It  lowers  the  temperature  3^  C,  and  induces  signs  of 
asphyxia,  but  not  so  markedly  as  chloroform  ;  also  mus- 
cular relaxation  and  anaesthesia  for  several  hours ;  i  or  2 
c.a  and  4  to  6  c.c.  in  dogs,  cause  less  asphyxia,  but 
more  somnolence  and  lowering  of  temperature,  without 
complete  abolition  of  sensibility,  6  or  8  grains  causes 
only  drowsiness  in  man ;  it  gets  into  the  urine.  Formic 
and  acetic  ethers  are  largely  used  in  combination  with 
other  compounds  of  methyl,  ethyl,  and  amyl,  in  the* 
manufacture  oi  fruit  essences,  which,  with  the  exception 
of  the  essence  of  orange,  are  rarely,  if  ever,  made  from 
the  fruits  after  which  they  are  named.  But  the  addition 
of  formic  ether  to  sulphuric  ether  has  been  suggested,  on 
account  of  the  great  reduction  of  temperature  which  it 
causes,  for  inhalation  in  surgical  operations,  which,  like 
ovariotomy,  are  apt  to  be  followed  by  extensive  inflam- 
mation. 

Picric  Acid,  or  carb-azotic,  is  formed  by  the  action 
of  nitric  acid  on  salycin  and  its  derivatives,  on  phloridzin, 
indigo,  aloes,  benzoin,  silk,  etc.  It  gives  ofl"  yellow, 
suflbcating  vapors,  is  acid,  and  extremely  bitter  of  taste. 
It  is  soluble  in  water,  alcohol,  and  ether,  and  stains  the 
skin  permanently  yellow.  Its  aqueous  solution  precipi- 
tates gelatine.  Its  salts  are  mostly  yellow,  and  have  a 
bitter  taste.  Potassium  picrate  dissolves  in  260  parts  of 
water.  Given  continuously  to  rabbits,  it  causes  emacia- 
tion, diarrhoea,  ecchymosis  of  the  intestines,  and  yellow- 
ness of  the  conjunctiva  and  urine.  In  large  doses '\X,czm%^^ 
nausea,  diarrhoea,  and  flatulence,  with  debility,  and 
twitching  of  the  cutaneous  muscles.  It  partially  dissolves 
the  blood-disks,  and  in  the  white  corpuscles  the  nuclei 
exhibit  a  lively  molecular  movement.  In  man  it  causes 
yellowness  of  the  eyes,  skin,  and  urine,  and  is  supposed 
to  illustrate  the  mode  of  production  of  jaundice  in  certain 
cases,  as  in  yellow  fever  and  acute  yellow  atrophy  of  the 
liver.  It  is  a  supposed  remedy  for  acholia^  or  entire  de- 
ficiency or  suppression  of  the  secretion  of  bile.  Picric 
acid  is  trinitophenol,  or  a  trinitophenic  acid,  and  is  now 
generally  derived  from  phenol.  Its  intensely  bitter  taste 
gives  it  its  common  name,  from  pikros,  bitter.  If  heated 
suddenly,  it  and  its  salts  explode  with  violence.  It  stains 
animal  tissues  yellow,  and  is  used  by  histologists ;  is 
largely  used  in  dyeing,  and  is  fraudulently  added  to  beers 
to  make  them  bitter.  It  is  of  value  in  toxicological 
analysis,  as  it  antidotes  and  precipitates  alkaloids  from 
their  solutions. 

Oxalic  Acid  exists  in  combination  with  ammonia,  in 
guano,  with  calcium  in  many  plants,  such  as  rhubarb, 
curcuma,  ginger,  squills,  orris,  valerian,  quassia,  and  as  acid 
potassium  oxalate  in  phytolucca,  belladonna,  rumex,  and 
oxalis,  most  lichens,  and  many  vegetables.  Some  urinary 
calculi  consist  of  oxalate  of  calcium.  It  is  also  found  in  the 
gall-bladder,  in  uterine  mucus,  and  in  urinary  sediments. 
It  is  formed  by  the  action  of  nitric  acid  on  most  or- 
ganic compounds ;  even  sugar,  gum,  and  sawdust  yield 
oxalates  when  heated  with  hydrate  of  potassa  or  sodium. 
It  is  generally  made  from  sugar,  molasses,  or  starch,  with 
nitric  acid  ;  one  hundred  parts  of  sugar  make  fifty-eight  to 


sixty  of  oxalic  acid.  The  dark  mother  liquids  left  in  the  pre- 
paration of  tartaric  acid  yield  it.  Treated  with  glycerine, 
it  is  decomposed  into  carbonic  and  formic  acids.  Acid  po- 
tassium oxalates,  called  salts  of  sorrel  or  salts  of  lemon,  will 
remove  iron  stains  from  paper,  linen,  and  leather,  but 
oxalic  acid  is  generally  used.  Its  taste  is  intensely  sour. 
Large  doses  cause  vomiting,  with  burning  pain  and  con- 
striction of  the  throat  and  stomach.  The  vomits  are 
dark-colored,  and  may  contain  blood.  When  the  pain  is 
very  severe,  collapse  may  ensue,  with  drowsiness.  Some- 
times  the  symptoms  are  unaccountably  long  delayed 
Some  patients  may  live  to  the  twenty-third  day,  but  death 
may  occur  in  from  three  to  twenty  minutes,  or  eight  hours. 
Dark  discoloration  of  the  oesophagus,  stomach,  gelatini- 
form  softening  of  the  stomach,  and  even  perforation  of  it 
may  occur.  The  blood  is  said  to  be  universally  bright  in 
color.  Antidotes :  Chalk  in  water,  slaked  lime,  dtied  white- 
wash, etc.  It  is  one  of  the  mobt  rapid  and  unerring  of  the 
common  poisons,  and  hence  has  rarely  been  used  in  the 
treatment  of  disease.  Still  it  can  be  as  safely  handled  as 
arsenic,  aconite,  or  atropine.  It  has  been  suggested  in 
an  induration  of  the  stomach  and  sclerosis  of  other  or- 
gans, especially  of  the  brain  and  spine,  in  which  it  causes 
softening.  It  seems  to  have  a  specific  action  on  the 
lumbar  and  dorsal  spinal  cord.  In  one  case  there  was 
great  weakness  and  numbness  of  the  legs  and  back,  so 
that  the  patient  could  scarcely  stand,  much  less  walk. 
In  another  case  the  first  thing  complained  of  was  acute 
pain  in  the  back,  gradually  extending  down  the  thighs, 
occasioning  ere  long  great  torture.  In  a  third  case  the 
patient  complained  more  of  the  pain  shooting  down  from 
the  loins  to  the  thighs  and  legs,  than  of  the  pain  in 
the  belly.  In  a  fourth  case  there  was  numbness,  ting- 
ling, and  pricking  in  the  back  and  thighs.  In  a  fifth  case, 
there  was  almost  complete  loss  of  power  and  motion  in 
the  legs,  which  did  not  pass  off  for  fifteen  days.  It  evi- 
dently must  be  suited  to  diseases  of  the  spinal  cord,  op- 
posite, or  very  different  from  those  which  it  produces. 
The  only  preparations  which  are  used  are  the  oxalates 
of  cerium  and  iron.  The  former  sometimes  controls 
vomiting,  due  to  reflex  irritation  from  pregnancy,  nervous 
and  uterine  derangements.  It  is  very  insoluble,  and 
hence  often  inert,  and  has  been  given  in  doses  of  firom  i 
to  8  grains  three  or  four  times  a  day.  The  oxalate  of  iron 
is  also  comparatively  insoluble,  and  hence  nearly  inert 

Hvdrobromate  of  Quinine  consists  of  potassii  bro* 
midii,  gr.  162  ;  acid,  tartaric,  gr.  198  ;  quinise  sulph., 
gr.  60 ;  aquae,  |  iij.  Filter.  Dose,  30  to  60  minims.  For 
hypodermic  injections  and  for  intermittents  with  con- 
gestion of  the  brain  or  spleen. 

Hydrobromic  Acid  has  an  agreeable,  acidulous  taste, 
and  most  of  the  physiological  and  therapeutical  actions 
of  the  bromides,  while  it  is  far  less  apt  to  cause  acne.  It 
is  also  a  corrigent  to  iron,  and  prevents  the  headache  so 
often  accompanying  its  full  action  and  that  of  quinine. 
Added  to  a  mixture  of  quinine  and  water,  it  will  make  a 
clear  solution  in  the  proportion  of  two  minims  to  each  grain 
of  quinine.  Added  to  aconite,  it  is  one  of  the  most  sooth- 
ing and  efficacious  remedies  in  fevers  and  inflammarions  at- 
tended with  great  nervousness,  restlessness,  even  delirium. 
It  is  said  not  to  be  useful  in  epilepsy.  Dose  of  the 
dilute  acid,  30  to  60  minims,  largely  diluted  in  water. 

Normal  Valerianic  Acid  is  a  butylformic  acid,  ob- 
tained by  the  oxidation  of  normal  amylic  alcohol ;  it  is 
an  oily  liquid,  and  has  an  odor  resembling  that  of  butyric 
acid.  Ordinary  valerianic  acid  is  delphinic  acid,  discov- 
ered by  Chevreul  in  181 7  in  the  oil  of  the  porpoise 
{Delphinum  phocena\  and  subsequently  in  the  valerian 
and  angelica  roots.  It  is  also  formed  during  putrid  fer- 
mentation or  oxidation  of  albuminoid  substances,  and 
occurs  in  the  urine  and  faeces  in  typhus  fever,  variola, 
and  acute  atrophy  of  the  liver.  It  is  an  oily,  colorless 
liquid,  with  a  penetrating  odor,  like  a  mixture  of  valerian 
and  old  cheese,  and  sharp  acrid  taste.  It  dissolves  in 
thirty  parts  of  water,  and  in  alcohol  and  ether  in  all  pro- 


August  23,  1884.] 


THE   MEDICAL  RECORD. 


223 


portions.    It  is  a  little  remarkable  for  dissolving  phos- 
phorus.   It  is  found  in  the  flowers  of  Anthemis  nobilis, 
or  chamomile,  and  wormwood,  but  is  prepared  almost  ex- 
dasively  by  oxidizing  amylic  alcohol  with  bichromate  of 
potash  and  sulphuric  acid.     Given  with  water  it  is  less 
disagreeable,  and  leaves  a  sweet  after-taste.     Valerianic 
acid  bears  the  same  relation  to  amylic  alcohol  that  acetic 
add  does  to  ordinary  alcohol     Its  neutral  salts  are  in- 
odorous when  dry,  and  may  be  given  in  wafers.     Apple- 
oj],  from  applejack,  is  amyl  valerianate.     It  coagulates 
albumen,  serum,  milk,  and  is  slightly  irritating  to  the 
skiiL    Its  odor  is  not  imparted  to  urine  and  blood,  but 
may  be  perceived  in  the  peritoneal  cavity,  which  renders 
it  useful  in  some  peritoneal  diseases,  especially  false  peri- 
tonitis.   It  quickens  the  heart's  action  and  respiration, 
then  produces  debility.   In  rapid  death  from  it  the  gastric 
mucous  membrane  is  pale,  hence  it  produces  paralysis  or 
collapse  of  it.    Valerianic  acid  is  not  used  alone  in  medi- 
cine, and  its  combinations  are  useless  except  the  valeri- 
anate of  ammonia.     Angelica  archangelica  is  rarely  used 
in  this  country,  but  it  is  far  more  agreeable,  and  quite  as 
efficacious.    Valerian  contains  one  or  two  per  cent,  of  an 
essential  oil,  the  dose  of  which  is  two  to  eight  minims, 
and  is  said  to  reduce  the  reflex  excitability,  motility,  and 
sensibility,  and  even  to  antagonize  the  tetanizing  action 
ofbrucia.     The  chief  use  of  valerian  is  in  the  treatment 
of  nervousness,  hysteria,  and  hysterical  disorders  gener- 
ally.   There  is  no  doubt  as  to  its  great  value  in  these 
cases.    In  epilepsy,  chorea,  and  paralysis  agitans  valeri- 
anic acid  is  to  be  preferred.    The  elixir  of  the  valerianate 
of  anmionia  is  not  nearly  as  useful  as  the  tincture,  solid 
or  fluid  extract,  or  the  oil,  or  acid.     It  has  not  yet  been 
used  in  combination  with  phosphorus  or  camphor. 

Cancer  Statistics  in  England. — At  the  Cancer 
Hospital,  Brompton,  1,974  cases  of  true  cancer  were 
treated  either  as  out-patients  or  in  the  wards.  Of  these 
841  were  cases  of  epithelial  cancer,  438  occurring  in 
males,  403  in  females  ;  1,069  were  registered  as  **  scirr- 
hos,"  54  in  males,  1,015  ^  females ;  64  were  registered 
as  "soft  or  medullary  cancer,"  18  in  males,  46  in  females. 
Cases  described  as  "  osteoid  "  and  **  colloid  "  are  not  in- 
dnded  in  the  above  computation.  The  following  statis- 
tical statements  regarding  the  above  cases  of  scirrhous 
and  epithelial  cancer  have  been  prepared  at  the  hospital : 
Average  duration  of  disease  previous  to  coming  to  hospi- 
tal: sdrrhus,  15.23  months;  epithelial,  20.5  months. 
Had  relations  previously  affected  with  cancer,  81.  Aver- 
age age  when  attacked  :  scirrhus,  48  years ;  epithelial, 
51  years.  Had  been  previously  operated  on  :  scirrhus, 
138;  epithelial,  102.  Average  lapse  of  time  before  dis- 
ease returned:  scirrhus,  21  months;  epithelial,  20 
months.  Cases  ascribed  to  blow  or  injury  :  scirrhus,  60 ; 
epithelial,  18. — British  Medical  Journal, 

The  Treatment  of  Dysentery  with  Corrosive 
SuBUMATK  AND  CoLOCYNTH. — Dr.  S.  B.  Childs,  of  Brook- 
Ip,  writes  :  '*  The  methods  ordinarily  advocated  for  the 
treatment  of  dysentery  being  generally  unsatisfactory, 
and  for  the  reason,  to  my  mind,  of  being  irrational,  I 
vould  fain  bring  before  the  medical  profession  a  mode 
of  treatment  that  at  my  hands  has  produced  desirable  re- 
sults. Pathologically  considered,  we  have  in  dysentery  a 
localized  inflammation,  either  catarrhal  or  fibrinous,  of 
the  mucous  and  submucous  membrane  of  the  lower  in- 
testinal tract  That  one  case  may  be  wholly  catarrhal, 
mother  case  wholly  fibrinous,  or  that  the  catarrhal  may 
nin  into  fibrinous,  has  been  amply  proven.  With  any 
of  these  conditions  present  the  majority  of  medical  wri- 
ters still  advocate  sugar  of  lead,  opium,  etc.,  ad  nauseam. 
Hardly  a  mixture  is  given  that  does  not  contain  more  or 
less  opium.  Now,  paxalyzing  the  contractility  of  the  intes- 
tinal walb  by  this  nervous  sedative  certainly  does  not 
care.  Castor-oil  and  Epsom  salt  have  been  recom- 
mended, but  generally  in  too  large  doses,  and  then  withal 
they  invariably  have  as  an  adjunct  some  preparation  of 
opmm.    Having  an  inflammation  of  a  severe  type,  it 


would  seem  a  desideratum  to  give  some  form  of  medicine 
that  would  produce  an  alterative  action  directly  in  the 
tissues  involved,  and  yet  at  the  same  time  not  to  excite 
any  disturbing  influence  on  the  system  at  large.  Now, 
we  have  in  small  doses  of  bichloride  of  mercury  just  what 
will  answer  this  requirement.  The  griping  pains  and 
tenesmus  that  are  so  distressing  in  this  complaint  can  be 
readily  controlled  by  tincture  of  colocynth  in  minute 
doses.  My  mode  of  procedure  is  to  give  the  mercury 
alternately  with  the  colocynth,  and  on  the  pain  being  re- 
lieved to  supersede  the  colocynth  with  the  tincture  of 
ipecac."  Dr.  Childs  then  gives  notes  of  two  cases  illus- 
trating the  eflicacy  of  his  treatment.  In  the  early  acute 
stage  he  gave  tincture  coloc3mth  in  gtt.  -^  doses,  alter- 
nating every  half  hour  with  corrosive  sublimate,  gr.  -j^^. 

Musk. — Although  musk  has  been  long  well  known  in 
the  West,  yet,  says  Dr.  Macgowan  in  his  report  on  the 
health  of  Wenchow  (**  Imperial  Maritime  Customs  "),  it 
seems  worth  while  to  translate  what  Chinese  writers  have 
to  say  about  it.  The  musk-deer  is  found  throughout  the 
mountains  of  Yiinnan,  Szechwan,  and  Thibet ;  it  is  a 
timid  little  animal,  and  often  dies  of  fright.  It  feeds  on 
juniper-leaves  and  reptiles  ;  snake-bones  are  found  in  its 
stomach.  In  spring  its  glandular  pouch  is  greatly  swollen 
and  inflamed.  The  secretion  is  discharged  with  the 
urine.  Musk-deer  always  resort  to  the  same  place  for 
micturition,  and  cover  their  urine  with  earth.  In  such 
places  deposits  of  a  superior  quality  are  found,  amount- 
ing sometimes  to  fifteen  catties  (a  catty  is  a  Chinese 
weight  of  about  one  and  one-third  pound).  The  arti- 
cle which  is  most  prized  is  that  which  falls  from  the  musk- 
deer  on  to  the  ground,  and  is  gathered  in  grains  that  are 
as  precious  as  pearls.  These  deposits  are  so  [pungent 
that,  i£  carried  through  a  garden  or  woods,  it  prevents 
fructification.  The  poisonous  effect  of  fresh  musk  on 
vegetation  is  shown  also  by  the  blighted  appearance  of 
places  which  the  musk-deer  selects  for  its  convenience. 
For  some  distance  around  these  places  there  is  an  ab- 
sence of  plants,  and  farther  off  the  leaves  exhibit  a  yellow 
tinge.  This  valuable  substance  no^  sooner  leaves  the 
hunter's  hands  than  skilful  manipulators  adulterate  the 
article  for  wholesale  dealers,  who  further  adulterate  it 
for  the  trade,  by  which  time  it  contains  only  about  ten 
per  cent  of  genuine  musk.  Musk  is  said  to  be  an  an- 
thelmintic, and  to  cure  the  bites  of  venomous  serpents.— 
Lancet. 

Mr.  Lawson  Taft  on  Pneumonotomy. — Mr.  Law- 
son  Tait  has  written  to  the  British  Medical  Journal  the 
following  letter,  which  we  believe  most  persons  will  agree 
is  an  eminently  sensible  view  of  the  case  :  "  Sir  :  I  think 
the  facts  that  the  idea  of  the  application  of  surgery  to  the 
diseases  of  the  lungs  occurred  to  Sir  Spencer  Wells  forty 
years  ago,  and  to  others  before  him ;  that  all  of  us  en- 
gaged m  the  surgery  of  the  abdomen  must  have,  as  I 
have  often  done,  restlessly  discussed  the  possibility  of 
passing  above  the  diaphragm  ;  and  yet  that  nothing  has 
been  done,  form  a  sufficiently  trenchant  statement  of  the 
case.  Nothing  has  been  done  beyond  the  drainage  of 
old  suppurating  pleurisies,  and  possibly  a  few  gangrenous 
vomicae ;  and  I  do  not  think  it  is  likely  that  we  shall  go 
much  beyond  this,  in  spite  of  Dr.  Biondi's  experiments. 
I  have  had  several  cases  of  thoracic  disease  sent  to  me, 
with  the  tempting  request  that  I  should  attempt  an  oper- 
ation ;  but  I  have  never  seen  my  way  to  the  effort,  they 
were  all  so  clearly  cases  of  malignant  disease.  I  cannot 
imagine  that  any  man  in  his  senses  would  attempt  to  re- 
move a  human  lung  with  a  tumor  in  it.  It  would  not  be 
resection  of  parts  of  four  ribs  which  would  permit  the  re- 
moval of  a  tumor  sufficiently  large  to  adinit  of  accurate 
diagnosis ;  and  I  cannot  observe,  in  the  literature  just  at 
the  moment  accessible,  that  any  other  kinds  of  tumors 
occur  in  the  lung,  save  those  of  hydatid  origin,  and  those 
of  a  cancerous  nature.  If  the  tumor  were  hydatid,  the  re- 
moval of  the  lung  would  be  unnecessary.  If  the  tumor 
proved  to  be  an  aneurism,  the  disaster  would  be  awful. 


224 


THE  MEDICAL  RECORD. 


[August  23,1884. 


For  phthisis,  I  imagine  removal  of  the  lung  would  be  a 
still  more  absurd  proposal.  If  one  lung  were  riddled 
with  vomicas,  the  chances  of  the  other  lung  being  affected 
would  amount  to  certainty.  If  there  were  only  one  lar^e 
cavity,  not  of  tubercular  origin,  or  very  chronic  in  its  his- 
tory, drainage  would  suffice.  The  £aicility  with  which  Dr. 
Biondi  has  removed  lungs,  and  parts  of  lungs,  from  dogs, 
guinea-pigs,  cats,  fowls,  pigeons,  and  sheep,  and  the  ab- 
sence of  mortality  from  such  operations,  is  likely  to  be  a 
snare  rather  than  a  help.  It  does  not  need  saying  that 
the  removal  of  a  healthy  lung,  collapsed  by  the  introduc- 
tion of  air  into  the  pleura,  would  be  a  very  easy  matter, 
and  very  different  from  the  removal  of  a  diseased  and 
adherent  organ.  There  would  be  as  much  difference 
as  there  is  between  normal  ovariotomy  and  removal  of 
a  pyosalpinx.  It  is  perfectly  clear  that  these  animals, 
with  their  deep  and  narrow  chests,  differ  very  much  from 
us,  with  our  wide  and  shallow  cavities,  in  their  powers  of 
enduring  the  accident  of  acute  pneumothorax;  certainly 
they  would  differ  from  us  immensely  in  the  facility  with 
which  pneumonotomy  may  be  performed.  Their  chests 
are  built  for  the  endurance  of  the  special  efforts  of  great 
speed,  and  we  have  lost  those  physical  characters  ;  and 
I  venture  to  say  that,  if  acute  pneumothorax  were  sud- 
denly inflicted  upon  sixty-three  healthy  adult  human 
beings,  death  would  be  the  immediate  result  in  the  great 
majority  of  the  experiments.  The  analogy  between  ne- 
phrectomy and  pneumonotomy,  of  which  Sir  Spencer 
Wells  makes  use,  is  also  a  misleading  one ;  for  the  func- 
tions of  the  kidney  may  be  interfered  with  to  a  consider- 
able extent,  and  even  entirely  for  a  considerable  period, 
without  apparent  trouble  ;  but  we  have  no  proof  that  this 
is  probable  in  the  case  of  the  lung.  The  only  experiment 
I  ever  saw  in  this  direction,  the  result  of  an  accident,  re- 
sulted in  immediate  death.  I  do  not  think  the  severest 
critic  can  say  of  me  that  I  have  any  tendency  to  obstruct 
surgical  progress;  but  it  seems  to  me  that  neither  d 
priori  reasoning,  nor  clinical  experience,  will  lead  us 
further  than  we  have  got  in  pulmonary  surgery — drain- 
age, with  the  useful  addition  of  costal  resection  in  old- 
standing  empyema ;  and  I  am  quite  sure  that  we  may 
regard  Dr.  Biondi's  experiments  as  the  outcome  of  the 
work  of  an  enthusiast,  misleading  in  their  tendency,  and 
dangerous  for  any  practicable  application  which  might 
be  made  of  them. — I  am,  etc,  Lawson  Tait." 

The  History  of  the  Discovery  of  the  Circula- 
tion, recapitulated,  divides  itself  naturally  into  a  series 
of  epoch-making  periods :  i.  The  structure  and  func- 
tions of  the  valves  of  the  heart,  £rasistratus,  B.C.  304. 
2.  The  arteries  carry  blood  during  life,  not  air,  Gsden, 
A.D.  165.  .3.  The  pulmonary  circulation,  Servetus, 
1553.  4.  The  systemic  circulation,  Csesalpinus,  1593. 
5.  The  pulmonic  and  systemic  circulations,  Harvey, 
1628.  6.  The  capillaries,  Malpighi,  x66i. — I)r.  Henry 
C.  Chapman. 

Perforating  Gunshot  Wound  of  the  Stomach 
AND  Liver. — Dr.  R.  M.  Stone,  of  Omaha,  Neb.,  sends 
us  the  following:  *'I  was  called  on  May  20th,  1884,  to 

see  Mike  P ,  who  'was  shot  in  the  bowels.'    I  found 

a  young  man  of  twenty-four,  hearty  and  vigorous  in  ap- 
pearance, lying  in  a  state  of  unconsciousness,  with  a  bul- 
let wound  of  entrance,  badly  powder-burned,  beneath  the 
mar^n  of  the  left  tenth  rib  and  three  inches  from  the 
median  line,  and  a  wound  of  exit  over  the  right  tenth  rib. 
The  patient's  pulse  was  good,  and  though  he  was  suffer- 
ing from  shock  yet  there  was  no  evidence  of  collapse 
from  serious  internal  hemorrhage.  I  had  determined  on 
my  way  out  to  the  case  to  perform  laparotomy  if  there 
was  evidence  of  serious  internal  hemorrhage,  but  finding 
no  evidence  of  such  condition,  and  no  definite  evidence 
of  perforation  of  the  stomach,  I  determined  to  treat  the 
case  expectantly,  but  saw  no  reason  to  hope  for  favora- 
ble results.  Dr.  James  Carter  saw  the  case  with  me  in 
the  evening,  and  agreed  with  me  in  the  very  unfavorable 
prognosis.  The  patient  died  nineteen  hours  after  re- 
ceiving the  wound,  and  at  my  request  Dr.  M.  A.  Robert 


made  the  autopsy.  We  found  that  the  abdominal  cavity 
was  partially  filled  with  bloody  fluid,  consisting  largely  of 
lemonade,  which  had  escaped  from  the  stomach.  The 
ball,  a  44-calibre,  had  wounded  the  omentum,  entered 
the  stomach  along  the  greater  curvature,  emerged  one- 
half  an  inch  from  its  entrance,  then  entered  the  liver  just 
above  the  gall-cyst,  ploughed  its  way  through  two  and  a 
half  inches  of  the  liver,  and  then  entered  the  right  ab 
dominal  wall,  fracturing  the  tenth  rib  and  emerged  over 
it  The  autopsy  demonstrated  that  a  laparotomy  could 
not  have  been  useful,  for,  though  the  wounds  of  the 
stomach  could  easily  have  been  sewed  up,  yet  the  lesion 
of  the  liver  and  the  violent  peritonitis  that  must  have  en- 
sued, together  with  shock,  would  have  proved  fatal" 

Extra-Uterine  Pregnancy  Ending  in  Suppurat- 
ing Cyst  of  Ten  Years'  Standing — PERiTONms— 
Autopsy. — Dr,  G.  C.  Park,  of  Murraysville,  Pa.,  writes : 
"  It  may  be  of  interest  to  the  readers  of  The  Medical 
Record  to  recite  through  the  columns  of  your  journal  a 
brief  history  of  the  case  of  the  wife  of  Dr.  W.  J.  R — -^ 
of  Newlonsbury,  Pa.  She  became  pregnant  for  the  first 
time  in  December,  1873,  ^^^  ^^^  ^  protracted  labor  of 
five  days  was  delivered  by  instnunents  on  September 
14,  1874.  Sl^c  made  a  good  recovery,  being  able  to 
attend  to  her  ordinary  household  duties,  and  only  com- 
plained of  slight  pain  below  the  umbilicus  and  to  the 
left  of  the  median  line  about  April,  1875.  ^^^  con- 
tinued to  perform  the  duties  of  a  mother  and  housewife, 
though  there  was  slight  tumefaction  near  the  sigmoid 
flexure  of  the  colon ;  and  in  May  or  June  of  the  same 
year  (1875)  >^^  passed,  by  the  bowels,  a  quantity  of 
pus,  estimated  by  her  husband  at  from  a  pint  to  a  quart. 
In  1878,  she  passed  a  quantity  of  hair  by  the  bowels. 
In  1882  she  passed  a  laige  quantity  of  pus  with  a  roll  of 
hair  estimated  at  from  three  to  four  inches  in  length, 
and  one  line  in  thickness.  On  May  11,  1884,  seven 
weeks  aflter  her  eighth  labor,  one  of  which  was  a  prem- 
ature, and  while  dressing  her  hair,  she  was  suddenly 
seized  with  a  pain  below,  and  to  the  left  of  the  umbilicus, 
accompanied  by  chilly  sensations,  but  no  rigor.  Symp- 
toms of  diffused  peritonitis  were  soon  manifest.  On 
May  19th  she  died,  aged  thirty-four  years  and  thirteen 
days.  By  her  own  request  we  were  permitted  to  have 
an  autopsy,  which,  with  the  assistance  of  Dr.  Ewing,  I 
conducted.  On  opening  the  abdominal  cavity  pus  oozed 
out,  which  was  preserved  and  estimated  at  a  quart 
The  bowels  were  all  glued  together  by  recent  adhesions. 
Pus  extended  from  the  bladder  to  the  diaphragm.  The 
left  lung  was  adherent  to  the  posterior  thoracic  wall.  At- 
tached to  the  sigmoid  flexure  of  the  colon  was  a  tumor 
not  much  larger  than  an  ordinary  -  sized  hen's  egg. 
This  was  divided  and  revealed  three  teeth,  one  very 
large  and  the  shape  of  the  canine  of  the  adult  Coarse 
dark  hair  lined  the  sac  containing  the  teeth.  A  mass 
weighing  about  a  pound  was  found  beneath  the  foetal 
tumor,  placental-like  in  consistency,  ragged  and  highly 
vascular.  The  right  ovaiy  showed  a  small  ovarian  tumor 
and  was  itself  hypertrophied.  The  stnmge  features  of 
the  case  «are  these :  i,  her  health  was  good  during  all 
this  time ;  2,  the  long  time  and  no  interference  with 
pregnancy  and  delivery ;  3,  pus  formed  and  escaped  by 
the  bowels  without  any  premonitory  symptoms.  On  May 
nth  the  pus-sac  broke,  discharging  the  contents  among 
the  bowels,  resulting  in  the  death  of  the  poor  woman, 
over  whose  head  the  sword  of  Damocles  had  been  sus- 
pended for  near  ten  years." 

Rectal  Etherization. — Dr.  S.  Banich,  of  this  dty, 
writes  :  ^'  Apropos  of  rectal  etherixation,  I  am  glad  yon 
are  giving  prominence  to  the  fact  that  it  is  dangerous.  I 
was  just  on  the  eve  of  adopting  it  in  an  operation  for 
trachelorrhaphy  after  hearing  it  highly  commended  by,  and 
afler  seeing  it  act  beautifully  in  the  practice  of,  one  of  our 
best  surgeons.  On  my  next  visit,  however,  I  learned 
that  a  patient  had  died  purely  from  the  effect  of  rectal 
etherization,  the  whole  intestinal  canal  having  been  found 
hemorrhagic." 


^,.-/5iOA.'L  l:£;:, 


The   Medical   Rec 

A   Weekly  yournal  of  Medicine  and  Surgery 


..>> 


ii.'. 


Vol.  96,  No.  9 


New  York,  August  30,  1884 


Whole  No.  721 


<3^0itmt  l^rtictes. 


ON  HAY  FEVER  AND  ROSE  COLD. 
By  MORELL  MACKENZIE,  M.D.  Lond., 

CDNSDLTmC  rOfTKUM  TO  THB  HOSPITAL  FOK  EHSSASBS  OF  THB  THKOAT  :  LBC- 
TVm  0:«  DISBASBS  OP  THB  THROAT  AT  THB  LONDON  HOSPITAL  MBDICAL 
COLLBOB ;  UiTB  PHTSIOAN  TO  THB  LONDON  HOSPITAL. 

In  a  lecture  on  hay  fever,  delivered  not  long  ago  at  the 
London  Hospital  Medical  College  (see  British  Medical 
Jwrnal^  May  7,  1884),  the  present  writer  alluded  to  the 
complaint  as  one  unknown  in  the  *'  good  old  times."  Now, 
tiioagb,  both  in  letter  and  spirit,  this  statement  is  perfectly 
correct,  it  too  much  ignores  the  fact  that  an  individual 
idiosyncrasy  rendering  people  sensitive  to  the  influence 
of  rose  pollen  was  not  very  uncommon  two  hundred  or 
three  hundred  years  ago.  As  the  term  "  rose  cold ''  has 
sorviyed  in  America,  while  it  is  quite  unknown  here,  I 
think  it  probable  that  the  complaint  may  be  much  more 
common  on  the  other  side  of  the  Atlantic  than  it  is  in 
England;,  and  it  is  with  the  view  of  eliciting  some 
''  modem  instances  "  that  I  venture  to  bring  under  the 
notice  of  my  fellow-workers  in  the  New  World  some  re- 
markable examples  of  rose  catarrh  as  related  by  writers 
of  the  sixteenth  and  seventeenth  centuries. 

As  early  as  the  year  1565,  Botallus '  (known  to  fame 
as  the  discoverer  of  the  foramen  ovale  xn  the  heart)  af- 
firmed that  he  knew  persons  who  held  the  smell  of  roses 
in  deadly  hatred,  because  it  gave  rise  to  headache,  sneez- 
ing, and  troublesome  itching  of  the  nose.  Somewhat 
later.  Van  Helmont '  (15 77-1644)  mentions  the  odor  of 
sveet-smelling  substances  as  causing  headache,  and  in 
some  cases  difficulty  of  breathing ;  he  also  gives  *  the 
case  of  a  canon  who  was  ioid  astate  propemodum  asthmati- 
cHSj  Mdque  hyetne  liber.  It  must  be  allowed,  however, 
that  this  passage,  though  suggestive,  is  not  quite  con- 
chsive  as  to  the  nature  of  the  malady.  In  1673  I.  N. 
finningarus^  says  that  he  has  often  heard  from  James  4 
ftmii,  a  professor  of  the  medical  faculty  in  the  University 
of  Basle,  that  his  wife,  Ursula  Faldsin  (a  lady,  as  he  is 
carefbl  to  inform  us,  whose  charms  were  of  the  '<  too,  too 
solid''  kind,  ampli  corporis  et  carnosi),  suffered  from 
ooiyza  for  several  weeks  every  year  during  the  rose 
season. 

A  few  years  later  we  find  Ledelius  *  recounting  ^e 
case  of  a  merchant  of  GrOnberg  who  could  not  smell  a 
rose  without  immediately  suffering  from  itching,  followed 
hf  inflammation  of  ^e  eyes,  wiSi  profuse  ladirymation 
and  headache  lasting  some  da3rs.  We  come  next  to  a 
case  of  especial  interest,  which  was  published  in  1691  by 
L  Constant  de  Rebecque.*  This  passage  is  important  as 
conveying  the  result  of  an  experienced  physician's  ob- 
servation of  his  own  symptoms.  He  tells  us  that  for 
thirteen  years  he  had  been  afflicted  with  coryza  during 
the  rose  season,  which  per  totum  tetnpus  quo  rosa  se  mihi 
^jfaciendas  prabent  durat  eoque  elapso  sponte  desineU 


'CoouBcnanoli  duo  alter  Ae  medici.  alter  de  aegroti  munere,  Lugduni,  1565^ 
p.  13. 

*A»hnaetTnsas,  cap.  x.  (Opera  Omnia,  Hafhs,  1707,  p.  344}. 

'Ibid.,  cap.  zxhr.  (Opera  Onmia,  p.  346). 

JOj».  ct  curat,  mcdidnal  ceatunae  qubque   centur.   secunda,  obs.   Ixxxvi. 
■?'**'f*"l*i  '673,  p.  ^2^. 

*UactIL  Nat.  Curios.  Tipaiae,  Dec.  ii.,  Ann.  a,  Obf.  140,  p.  309  (probably 

*  Atran  Medidnn  Helvetionim,  Obs.  rar.  et  curat  insign.,  obs.  92,  Geneva, 
"9«.  p.  150  «  seq. 


At  first  he  attributed  his  sufferings  to  heat,  but  in  the 
year  1685,  when  the  summer  was  exceptionally  hot  and 
there  were  hardly  any  roses  on  account  of  caterpillars,  he 
was  struck  by  the  fact  that  his  annual  disorder  did  not 
trouble  him.  The  symptoms  came  on  at  once,  however, 
after  inadvertently  plucking  a  rose  toward  the  end  of  the 
He  concludes  that  something  flows  from  roses 


season. 


{e  rosis  aliguid  effluere)  which  stings  the  nose  (in  his 
case  exceptionally  sensitive)  and  aculeis  quibusdam  solu- 
iionem  continui  et  si  non  sensibus  obviam  excitet.  This 
observer,  therefore,  came  very  near  the  mark  as  to  the 
real  cause  of  the  disease,  to  which  he  applied  the  term 
coryza  a  rosarum  odore. 

An  extraordinary  case  is  related  by  Herlinus  *  (on  the 
authority  of  Adrian  Spigelius,  whose  name  still  survives 
in  one  of  the  lobes  of  the  liver)  of  a  Roman  cardinal, 
Oliver  Caraffa,  who  could  not  bear  the  smell  of  roses. 
This  is  confirmed  from  p>ersonal  knowledge  by  another 
writer,*  who  adds  that  Caraffa  was  obliged  every  year  to 
shut  himself  up  during  the  rose  season,  guards  being 
stationed  at  all  the  gates  of  the  palace  to  stop  any  visi- 
tor who  might  be  wearing  or  carrying  the  dreaded  flower. 
It  is,  of  course,  possible  that  in  this  case  the  roses  may 
have  produced  some  other  affection  than  rose  fever,  but 
as  it  is  distinctly  stated  that  it  was  the  smell  to  which  the 
cardinal  objected,  we  may,  I  think,  fairly  conclude 
that  the  "  sting  of  the  flesh  "  which  tormented  him  was, . 
in  fact,  rose  pollen. 

About  the  end  of  the  seventeenth  century  Riedlin  re- 
lates the  case  of  a  merchant  with  whom  he  was  acquainted 
who  was  afflicted  with  sneezing  and  catarrh  every  year 
when  the  roses  were  in  bloom.  Riedlin  advised  his 
patient  to  avoid  the  cause  of  his  complaint,  a  point  be- 
yond which  we  have  not  even  yet  advanced. 

Heberden's  *  observations  niake  a  kind  of  connecting 
link  between  the  rose  catarrh  of  the  seventeenth  century 
and  the  hay  fever  of  the  nineteenth,  for  though  this  phy- 
sician does  not  seem  to  have  been  at  all  aware  that  the 
complaint  had  any  connection  with  flowering  plants,  he 
mentions  casually  that  five  of  his  patients  suffered  from 
catarrh  for  a  month  every  summer,  while  another  was 
similarly  affected  during  the  whole  of  that  season. 

The  author  of  this  paper  will  feel  greatly  indebted  to 
any  American  physician  who  may  be  able  to  brins  under 
his  notice  any  well-authenticated  case  of  rose  cold. 

19  Hablby  Sranr,  Lomdoii,  W. 


A  Maternal  Impression. — Dr.  F.  W.  Epery,  of  New 
Richmond,  Wis.,  writes:  '<A  lady  in  her  second  preg- 
nancy was  much  affected  and  greatly  annoyed  by  a  de- 
formed brother-in-law,  who  spent  his  whole  time  in  the 
house  and  constantly  complained  about  his  imaginary 
ills — as  he  was  a  confirmed  hypochondriac.  His  de- 
formity consisted  in  a  very  pronounced  posterior  curva- 
ture in  the  upper  dorsal  and  lower  cervical  vertebra,  a 
long  neck  approaching  the  horizontal,  with  head  deficient 
in  occipital  region.  When  the  child  was  bom  it  had  pre- 
cisely the  same  posterior  curvature,  and  there  was  a  com- 
plete arrest  of  development  from  the  first  cervical  vertebra 
to  the  frontal  bone.  There  was  no  brain,  and  the  face 
resembled  that  of  the  deformed  brother-in-law." 

1  Henricus  Herlinus :  De  Remediia  sudoriferis  et  analepticisf  page  3a.    Lipine, 

«  Job.  Pierius  .  Hieroglypbica,  lib.  8,  cap.  ^s^  page,  96.     Francofiirti,  1678. 

*  Linca  Medicae,  Augustae  Vindelicorum,  1695,  p.  177. 

*  Commentarii  de  Morborum  historii  et  curatione,  Londini,  i8o9,  cap.  xxiv., 
De  DestiUatione,  p.  1x8  et  &eq. 


226 


THE  MEDICAL  RECORD. 


[August  30,  1884. 


ON  SOME  DISORDERS  OF  NUTRITION  RE- 
LATED  WITH  AFFECTIONS  OF  THE  NER- 
VOUS SYSTEM. 

Being  the  Address  in  Medicine  Delivered  Before 
THE  British  Medical  Association  at  its  Meeting 
IN  Belfast,  Ireland,  July  30,  1884. 

By  WILLIAM  M.  ORD,  M.D.,  F.R.C.P., 
<iciAN  TO  ST.  Thomas's  hospital,  lonoon,  bmcland. 
(Special  for  Thb  Mkdical  Rsoobo.) 
(Condaued  fiom  page  an.) 

Mu  ular  wasting  coexistent  with  joint  disease,— 
For  some  years  I  have  been  led  to  observe,  in  a  certain 
grojp  of  cases  of  chronic  rheumatic  arthritis,  the  coex- 
istence with  the  joint-lesion,  always  well  marked,  of 
affections  of  muscles.  These  have  been  not  merely 
weakness  of  extensors,  and  tonic  contraction  of  flexors, 
the  two  factors  which  largely  determine  the  character  of 
the  deformities  of  the  disease,  but  marked  and  excessive 
wasting  of  muscles,  closely  resembling  those  of  progres- 
sive muscular  atrophy.  Together  with  these,  I  have 
noted  the  existence  of  fibrillar  tremors,  and  of  electrical 
reactions  like  those  of  progressive  muscular  atrophy  in 
the  general,  but  with  some  indications  of  less  loss  of  gal- 
vanic than  of  faradic  sensibility,  with  some  slight  indica- 
tion of  the  reaction  of  degeneration. 

In  addition  to  those,  I  have  noticed,  as  others  before 
me  have  noticed,  a  wasting  of  the  tissues  other  than  the 
muscles  of  limbs. 

These  concern,  in  the  hands,  loss  of  substance  in  the 
soft  parts  of  the  digits,  the  wasting  of  the  skin,  which 
brings  about  a  satiny  or  glossy  quality  of  the  surface,  and  a 
dwindling  of  the  nails,  which  we  see  carried  to  the  full  in 
extreme  true  gouty  affection  of  the  fingers,  where  the  nails 
become  small  scaly  appendages  of  the  carrot-likedigits. 

In  some  cases  I  have  also  observed  exaggeration  of 
the  so-called  tendon-reflexes,  and  in  some  fibrillar  tre- 
mors. In  fact,  as  they  present  themselves  to  me,  these 
are  cases  of  progressive  dystrophy  of  joints  marching  with 
progressive  atrophy  of  muscles,  and  with  atrophy  of  the 
other  tissues  of  limbs.  My  fi-iend,  Dr.  Hadden,  who  has 
taken  great  interest  in  these  cases,  has  recently  presented 
a  paper  to  the  Clinical  Society  of  London,  taking  up 
some  of  the  points  here  mentioned,  I  may  here  relate 
two  cases  which  bear  upon  this  relation. 

M.  K ,  a  married  woman,  a^ed  sixty,  was  recently 

under  my  care.  There  was  no  history  of  gout  or  rheu- 
matism in  her  parents,  but  she  had  one  sister,  who  was 
said  to  suffer  from  gout.  She  presented  the  lesions  of 
rheumatic  arthritis  in  the  hands,  knees,^  and  ankles,  but 
the  hands  were  most  affected.  The  muscles  of  both  arms 
were  distinctly  wasted ;  the  skin  of  the  ends  of  the  fingers 
was  glossy,  and  the  soft  tissues  around  the  two  last 
phalanges  were  much  wasted.  The  right  hand  was  af- 
fected more  than  the  left.  The  tendon-reflexes  were 
greatly  exaggerated,  both  at  wrist  and  elbow,  particularly 
on  the  right  side.  The  hands  showed  the  adduction  de- 
formity of  chronic  rheumatic  arthritis  rather  than  the 
claw  of  progressive  muscular  atrophy.  The  electrical 
reaction,  of  both  kinds,  was  lessened  ;  she  had,  therefore, 
slowly  progressing  in  company,  arthritis,  wasting  of  mus- 
cles, wasting  of  tissues  generally,  and  wasting  of  skin, 
without  the  reaction  of  degeneration.  I  could,  in  her 
case,  detect  no  reflex  cause.  She  was  anaemic,  but  not 
thin,  and  had  worked  hard.  The  case  certainly  pointed 
to  a  common  central  nervous  origin  of  all  the  dystrophies. 
A  case  now  under  care  is  more  interesting. 

The  patient,  a  man,  following  the  occupation  of  sales- 
man, and  not  the  victim  of  overwork,  has  been  ill  for  ten 
or  twelve  years.  He  suffered  firom  rickets  in  childhood  ; 
there  is  no  record  of  acute  rheumatism  in  his  own  life  or 
of  any  joint-affection  in  his  ancestry.  When  first  ill,  he 
had  occasional  attacks  of  weakness  in  his  limbs,  accom- 
panied by  swelling  in  the  ankles,  knees,  wrists,  and  fin- 
gers, never  in  the  shoulders  or  elbows.     These  attacks 


came  and  went,  leaving  him,  at  first,  well  in  the  intervals, 
but  for  some  years  he  had  not  been  possessed  of  proper 
muscular  power.  Two  years  ago  he  was  violently  shaken 
by  a  thunderstorm,  since  whidi  the  symptoms  of  which 
he  now  complains  have  appeared.  He  has,  now,  typical 
rheumatoid  arthritis  of  the  hands  and  feet;  the  right 
shoulder  is  stiff  and  painfiil  on  movement,  particularly  m 
abduction ;  there  is  grating ;  and  a  rim  can  be  felt  around 
the  articular  end  of  the  humerus.  The  elbow  is  not  in- 
volved, but  the  wrist  is  greatly  distorted,  almost  to  dislo- 
cation. There  is  wasting  of  the  interossei  of  the  hand, 
of  the  thumb-muscles,  of  the  muscles  of  the  forearm,  and 
in  an  excessive  degree  of  the  right  deltoid ;  the  right 
biceps  bein^  also,  but  not  so  profoundly,  wasted.  There 
is  no  paresis,  only  such  loss  of  motor  power  as  would 
correspond  to  loss  of  muscular  substance.  Marked 
fibrillar  twitchings  can  be  seen  in  the  arms,  being  more 
active  in  the  rieht.  The  feet  show  chronic  arthritis  with- 
out any  notable  wasting  of  muscles.  The  knees  are 
slightly  affected,  the  hips  free.  There  is  no  loss  of  sen- 
sation anywhere,  and  no  impairment  of  the  functions  of 
bladder  or  of  the  rectum.  The  deep  reflexes  are  raflier 
diminished,  the  superficial  not  affected.  The  electrical 
reactions  of  the  muscles  chiefly  affected  are  impaired. 
The  right  deltoid  is  much  less  sensitive  to  the  galvanic 
current  than  it  should  be,  and  responds  only  to  a  faradic 
stimulation  stronger  than  that  which  should  normally 
excite  it  The  biceps  give  the  same  reactions  in  a  lesser 
degree.  The  other  muscles  have  normal  reactions.  In 
this  case  there  is  no  histor;^  of  gout,  of  lead-poisoning,  or 
of  causes  likely  to  give  rise  to  spinal  trouble.  These 
dystrophies  of  muscle  and  nerve  are  not  accompanied 
by  dystrophies  of  skin.  The  joint-affection  was,  to  all 
appearance,  preceded  by  a  distinct  accession  of  muscular 
debility. 

Articular  dystrophie  brought  about  by  irritation  of 
spinal  cord, — If  the  considerations  upon  which  I  have 
been  dwelling  indicate  the  probability  that  some  such  in- 
fluence as  is  excited  by  the  spinal  cord  in  producing 
muscular  atrophy  may  produce  also  articular  dystrophy, 
there  are  others  which  bring  into  stronger  relief  the  infln- 
ence  of  the  spinal  cord  in  bringing  about  directly  affec- 
tions of  joints  independently  of  muscles.  I  cull  from  my 
note-book  a  typical  case  of  the  kind.  A  lady,  of  healthy 
family  and  healthy  personal  antecedents,  wen^  soon  after 
her  marriage,  to  an  evening  party.  For  the  reception  of 
a  large  number  of  guests,  a  tent  was  provided.  Rain 
fell  heavily  all  the  evening;,  and  saturated  the  canvas. 
For  certam  reasons  she  £d  not  dance,  but  sat  in  the 
tent  for  some  hours,  with  her  back  to  the  wet  walls,  ex- 
periencing, although  not  actually  in  contact  with  the 
moisture,  a  sense  of  intense  chill  in  the  back.  Within  a 
day  or  two  arthritis  set  in  in  both  knees.  It  was  not  in- 
tense, but  presently  gave  rise  to  much  swelling  and  de- 
formity. The  ankles,  hips,  elbows,  hands,  and  shoulders 
were  in  succession  attacked  with  the  same  trouble.  All 
the  joints  were  excessively  swoUen,  tender,  and  painfiil; 
but  the  muscles  were  not  noticeably  affected.  The  joint 
affection  was  one  of  steady  progression,  not  one  of  par* 
oxysmal  exacerbations,  followed  by  increased  mischief! 
and  ended  by  rendering  her  practically  helpless  as  reJ 
garded  locomotion,  simply  by  reason  of  pain.  Her  mus- 
cles retained  a  fair  bulk  and  strength  ;  the  reflexes  were 
exaggerated,  but  it  is  necessary  to  remark  that  the  great 
sensitiveness  of  the  joints  prevented  a  proper  investiga* 
tion  on  this  point.  The  electrical  reactions  were  not,  I 
am  sorry  to  say,  tested.  Her  mind  remained  singularly 
clear  and  well  balanced ;  her  bodily  functions  were  not 
affected;  she  became  the  mother  of  several  children; 
and,  in  spite  of  locomotive  difficulties,  manifested  an  ex- 
ceptional power  in  the  direction  and  discipline  of  her  j 
household.  All  the  effects  of  the  long  chill  received  by 
the  spinal  cord  seemed  to  fall  upon  the  joints  alone,  pro- 
ducing, in  a  typical  form,  a  progressive  rheumatic  (to  usej 
the  accepted  term)  arthritis.  After  reading  M.  Charcot's 
cases,  one  might  be  tempted  to  wonder  why  such  painful 


August  30, 1884.] 


THE  MEDICAL  RECORD. 


227 


action  of  jobts  should  not  have  been  followed  by 
atrophy  of  muscles.  But,  as  a  matter  of  observation,  I 
think  it  will  generally  be  found  that  the  influences  which 
give  rise  to  violent  reflex  reactions  are  themselves  mostly 
of  the  lighter  kind.  Those  which  are  superficial,  call 
oat  rapid  and  widespread  reaction,  as,  for  instance,  an 
iiritating  particle  in  the  nose ;  those  which  are  deep  and 
ioteose,  olH  out  the  more  concentrated  reactions  which 
end  in  an  inflammation,  or  are  proclaimed  by  severe  pain. 
This  is  but  a  parenthesis,  but  it  relates  to  a  point  in  re- 
flection of  irritation  which  is  worthy  of  deep  thought 

Observations  of  Senator  and  others  on  the  nervous 
^^tdudion  of  arthritis. — I  might  illustrate  this  point 
more  fully  from  my  records  of  cases,  and  should  do  so, 
vere  it  not  that  the  spinal  cord  origin  of  certain  kinds  of 
chronic  arthritis  has  been  already  contended  for  by  other 
observers.  Senator,  in  his  all  too  short  paper  on  Arthri- 
tis Deformans  in  *'  Ziemssen's  Cyclopaedia,"  speaks  thus  : 
^  Existing  observations  seem  to  point  exclusively  to  the 
peripheral  variety  of  the  disease,  as  connected  with  the 
affections  of  the  nervous  system.''  Remak  and  Benedikt 
were  probably  the  first  to  regard  articular  affections  as  a 
result  of  irritative  states  of  the  spinal  marrow  and  sym- 
pathetic. Indeed,  Remak  went  so  far  as  to  call  arthritis 
deformans  by  a  new  name,  '^arthritis  myelitica''  and 
"  myelitico-neurotica. " 

The  date  of  the  publications  in  which  these  views 
vere  advanced,  is  as  far  back  as  1863  and  1864.  Sena^ 
tor,  in  his  comments  on  them,  after  mentioning  a  case 
published  by  Kohts  in  1873,  in  which  this  disease  fol- 
lowed a  [right,  proceeds  to  say,  "The  usually  s)anmetri- 
cal  order  of  its  invasion  (the  invasion  of  arthritis  defor- 
mans), can  hardly  be  explained,  unless  we  assume  the 
existence  of  some  central  causes  situated  in  the  nervous 
system.  The  disease  is  often  associated  with  neuralgic 
and  tropho-neurotic  symptoms.  Finally,  some  results  of 
treatment,  particularly  diose  recorded  by  Remak  and 
others  concerning  the  effects  of  electricity  directed  to  the 
central  nervous  system,  serve  likewise  to  support  this 
view." 

That  it  should  be  regarded  by  Senator  as  diflicult  to 
explain  the  symmetrical  order  of  invasion,  except  upon 
the  assumption  of  a  central  nervous  irritation,  illustrates 
in  a  forcible  way  the  extinction  of  the  beliefs  of  one  gen- 
eradon  by  the  beliefs  of  its  successor.  Sir  James  Paget's 
"Lectures  on  Surgical  Pathology"  are  not  many  years 
old,— they  were  published  in  1853. 

In  this  most  fascinating  book,  written  by  a  man  whom 
I  may  ^ly  call  the  most  accomplished,  as,  indeed,  also 
the  most  eloquent  man  in  our  profession,  we  find  set 
forth,  in  the  most  convincing  way,  the  argument ''  that 
ail  symmetrical  diseases  depend  on  some  morbid  material 
in  ^e  blood,''  and  that  certain  blood  diseases  have 
'^ seats  of  election."  The  reasoning  upon  which  this  is 
based  is  found  later  in  the  book,  where,  on  pages  24 
aseq^Six  James  proceeds  to  develop  a  principle,  the 
germ  of  which  is  in  the  writings  of  Treviranus.  The 
sentence  of  Treviranus  is,  '*  that  each  single  part  of  the 
body,  in  respect  of  its  nutrition,  stands  to  the  whole 
body  m  the  relation  of  an  excreted  substance."  Accord- 
ing to  the  ideas  which  follow,  every  part  of  the  body  has 
its  special  nutritional  and  excretory  endowments,  inas- 
much as  it  di£fers  from  all  other  parts,  however  identical 
iu  superficial  seeming,  in  its  reaction  to  alterations  of  the 
Wood  When  there  ,is  symmetry  on  either  side  of  the 
vertical  plane,  the  corresponding  parts  agree  in  their 
reactions,  while  differing  from  all  others.  The  second 
diapter — on  the  conditions  necessary  to  healthy  nutri- 
tion— contains  a  most  interesting  sketch  of  the  influence 
of  the  nervous  system  on  nutrition  ;  but  the  main  ideas 
of  causation  are  independent  of  nervous  influence,  and 
rest  on  relations  between  the  blood  and  the  tissues. 

The  idea  of  some  such  special  endowment  cannot  be 
spoken  of  without  more  than  respect. 

It  is  held  still,  in  respect  of  cutaneous  diseases,  and  in 
respect  of  gout,  and  particularly  of  goutiness.     I  main- 


tain that  it  must  still  be  accepted  as  a  truth,  but  as  only 
a  part  of  the  truth,  as  regards  nutrition,  and  I  enter  my 
protest  against  the  short-sightedness  which  fails  to  recog- 
nize now  what  Sir  James  Paget  did,  in  his  well-balanced 
judgment,  recognize  thirty  years  ago,  the  possibility  of 
the  combined  action  of  two  dissimilu'  processes. 

To  resume  now  the  line  of  thought  which  has  been  ar- 
rested by  this  excursion,  let  us,  for  a  moment,  review  our 
position.  We  have  considered  possible  causation  of  dys- 
trophies of  muscle  by  irritation  of  joints,  of  dystrophies 
of  joints  by  injuries  of  bones,  of  dystroplues  of  joints  by 
a  sort  of  subjective  irritation  coming  through  channels 
of  centripetal  muscular  nerves,  of  dystrophies  of  joints 
and  muscles  by  irritation  or  disease  of  nervous  centres. 

Digitorum  nodi.  —  Are  these  all  the  channels  by 
which  nervous  influence  may  affect  the  nutrition  of 
joints  ?  I  think  not.  For  more  than  fifteen  years  the 
probability  that  the  form  of  chronic  rheumatic  arthritis, 
called  by  Heberden,  "digitorum  nodi,"  by  Haygarth, 
"  nodosity  of  the  joints ; "  by  Senator  and  others  the 
polyarticular  (I  am  not  responsible  for  the  hybridity  of 
the  term) — the  polyarticular  form  of  arthritis  deformans, 
is  in  many  cases  a  dystrophy,  determined  by  nervous  ir- 
ritation propagated  fi-om  the  uterus  to  the  spinal  cord, 
and  reflected  upon  the  joints,  has  presented  itself  to  me. 
Let  me  give  briefly  the  notes  of  a  case  which  I  saw  first 
in  the  year  1868. 

The  subject  was  an  unmarried  lady,  twenty-six  years 
of  age.  She  came  to  me  complaining  of  terrible  dys« 
menorrhoea,  and  of  what  she  had  been  taught  to  csdl 
rheumatic  gout  She  was  thin,  anasmic,  sallow  of  com* 
plexion,  had  abundant  acne  on  the  face,  and  was  hys- 
terical, having  given  up  society  and  all  active  occupation 
for  the  contemplation  of  her  ailments.  There  was  no 
small  justification  for  this  absorption.  Out  of  every 
month  of  her  life  she  had  only  one  week  of  ease.  The 
menstrual  period  lasted  one  week,  and  was  attended  with 
excessive  pain  in  the  pelvis  and  back.  A  week  before 
its  conmiencement  the  smaller  joints  of  the  extremities 
became  swollen  and  excessively  painful.  They  remained 
in  this  condition  till  the  end  of  the  week  following  the 
cessation  of  the  menstrual  period.  There  were  some 
variations  in  the  severity  of  the  d^smenorrhoea,  and  there 
were  corresponding  variations  m  the  intensity  of  the 
joint-affection.  During  the  week  of  ease  the  joints 
showed  a  little  deformity,  but  were  freely  movable,  and 
free  firom  pain  or  tenderness.  The  '<  rheumatic  gout " 
was  the  main  object  of  her  attention,  from  its  long  per- 
sistence ;  and  at  first  I  adopted  the  idea,  already  adopted 
by  others,  that  the  two  troubles  were  the  effect  of  a  com- 
mon cause,  a  rheumatic  inflammation  affecting  joints  and 
pelvic  organs  at  one  time.  Treatment  instituted  upon 
this  hypothesis  failed,  had  long  failed  to  give  any  relief, 
and  what  may  be  called  the  central  position  of  the  men- 
strual trouble,  led  me  to  the  opinion  that  it  was  the  pri- 
mary mischief  giving  rise,  in  some  way  that  was  then  not 
very  clear  to  me,  to  arthritis. 

The  uterine  conditions  were  now  steadily  attacked. 
At  the  end  of  a  twelvemonth's  treatment,  the  dysmen- 
orrhoea  was  subdued.  As  it  yielded,  the  joint-trouble 
dwindled;  and,  with  its  cessation,  the  rheumatic  par- 
oxysms disappeared.  So  did  the  acne,  the  unhealthy  com- 
plexion, and  the  general  ill-health.  At  the  present  time, 
this  lady  is  stout,  healthy,  and  vigorous  of  mind  and  of 
body  ;  but  the  joints  retain  some  painless  deformity.  In 
the  year  1869,  I  published  an  account  of  this  case,  and 
of  others  which  appeared  to  me  to  indicate  that  uterine 
irritation,  chiefly  associated  with  hyperaemiaof  the  organ, 
were  capable  of  reflection  upon  the  joints,  with  the  re- 
sult of  inducing  a  form  of  rheumatic  arthritis.  The  paper 
is  probably  little  known  to  you,  and  you  will  pardon  me 
if  I  present  to  you  some  of  its  matter  and  conclusions. 

Haygarth,  writing  in  the  year  1805,  on  the  "Clinical 
History  of  the  Nodosity  of  Joints,"  stated  that  he  had 
seen  thirty-three  cases  of  that  condition,  all  in  women. 
He  regarded  the  affection  as  peculiar  to  women,  and  as 


228 


THE  MEDICAL  RECORD. 


[August  30, 1884. 


belonging  to  the  climacteric  and  subsequent  periods  of 
their  life.  Only  three  out  of  his  thirty-three  cases  had 
the  '*  nodes'*  during  the  period  of  regular  menstruation. 
Of  these,  two  appeared  to  be  between  thirty  and  forty 
years  of  age ;  the  third  had  suffered  twelve  abortions. 
In  all,  the  fingers  were  chiefly  affected.  Haygarth  sepa- 
rated this  affection  as  ''nodosity  of  joints  "  from  '^ rheu- 
matic gout " — a  term  already  in  use  when  he  wrote  ;  and 
he  considered  it  to  be  chiefly  a  disease  of  the  middle  and 
higher  classes.  Curiously  enough,  when  I  analyzed  my 
note-book,  I  found  records  of  just  the  same  number  of 
cases — not  of  nodosity  of  joints  simply,  but  of  rheumatic 
arthritis,  combined  with  decided  symptoms  of  uterine 
disorder  or  irritation.  I  excluded  from  the  list  cases  in 
which  there  was  evidence  of  uratic  deposits,  and  cases  in 
which  no  known  uterine  complication  existed,  though 
both  classes  demanded  separate  attention,  as  forming 
chapters  of  the  history  of  arthritis. 

C5f  the  thirty-three,  twenty-six  belonged  to  the  middle 
and  upper  classes,  mostly  to  the  former,  the  remaining 
seven  to  the  poorer  classes ;  seventeen  were  unmarried^ 
thirteen  were  married,  and  three  were  widows. 

As  regards  age,  ten  were  between  twenty  and  thirty 
years ;  eleven  were  between  thirty  and  forty ;  nine  were 
between  forty  and  fifty ;  and  three  were  between  fifty  and 
sixty. 

The  indications  of  ovario -uterine  complication  in  the 
several  cases  comprehended  marked  irregularity  of  cata- 
menia  in  two ;  catamenial  flow  simply  in  excess,  one ; 
catamenial  flow  very  scanty  in  one  j  catamenia  irregular 
with  excess  in  two ;  catamenia  recently  disappeared  in 
four;  catamenia  recently  reappeared  after  apparent 
cessation,  the  reappearance  coinciding  with  arthritic 
attack,  in  two ;  dysmenorrhoea  with  excess  in  eight ;  dys- 
menorrhoea,  with  deficiency  in  four  ;  constitutional  symp- 
toms of  climacteric  present  in  two ;  fibroid  of  the  uterus 
with  menorrhagia,  but  not  dysmenorrhoea,  in  one ;  cata- 
menia regular,  relieving  pain  present  at  other  times  in 
sacral  region,  in  one ;  catamenia  excessive,  with  leucor- 
rhcea,  in  one;  profuse  leucorrhoea  in  woman  married 
several  years  without  pregnancy,  one ;  woman  married 
several  years  without  pregnancy,  one ;  case  in  which 
arthritis  occurred  on  two  occasions  a  week  before  parturi- 
tion, these  being  the  only  pregnancies,  one  ;  climacteric 
long  past,  arthritis  began  then,  and  has  since  continued, 
one. 

In  four  of  the  above  cases,  ovaritis  existed ;  and  it  is 
important  to  notice,  first,  that  amenorrhoea  is  not  noted 
in  any  case,  second,  that  the  conditions  noted  are  mainly 
such  as  would  involve  hjrpersemia  of  the  internal  genital 
organs;  third,  that  marked  dysmenorrhoea  is  noted  in 
twelve  or  more  than  a  third  of  the  total  number. 

The  seat  of  arthritis  was  various.  It  affected  tlie  hands 
alone  in  thirteen  cases ;  the  hands,  wrists,  and  elbows  in 
three ;  the  upper  extremities  in  one  ;  the  right  hand  only 
in  one ;  the  right  hand  and  wrist  in  one  ;  the  hands  and 
feet  in  one ;  the  hands,  feet,  and  knees  in  one ;  the  knees 
and  ankles  in  one ;  both  extremities  in  six ;  both  extrem- 
ities on  one  side  in  one ;  the  ankle  and  tendo  Achillis 
in  one.  From  this,  it  appeared  that  the  hands  were  more 
often  affected  than  any  other  parts,  the  metacarpo-pha- 
langeal  joints  being  of  all  joints  the  most  obnoxious  to 
this  form  of  arthritis.  The  hands,  besides  being  alone 
attacked  in  the  cases,  shared  the  affection  with  other 
joints,  and  principally  with  other  joints  of  the  upper  ex- 
tremity, the  wrists  excepted,  in  all  the  rest  of  the  cases, 
except  two.  In  three  of  the  cases,  where  the  affection 
was  limited  to  one  side  of  the  body,  or  having  begun, 
continued  excessive,  on  one  side,  there  were  ovarian  pain 
and  tenderness  on  the  same  side,  and  a  distinct  frequency 
of  neuralgia  on  the  same  side. 

An  inspection  of  the  cases  brought  out  further  most 
interesting  relations.  Not  only  did  the  arthritis  coincide 
with  ovano-uterine  affection;  but,  in  a  considerable  pro- 
portion of  cases,  paroxysms  of  arthritis  coincided  with 
menstrual  periods.      This   sort  of  parallel  march  was 


noted  in  fourteen  cases,  in  one  of  which  arthritis  pre- 
ceded  menstruarion  as  its  regular  herald;  in  seven 
arthritis  regularly  accompanied  ;  in  two,  it  followed ;  in 
two,  it  boUi  accompanied  and  followed ;  and  in  two 
arthritis  occurring  in  the  intervals  was  relieved  by  men- 
struation. 

Now,  if  these  had  been  so  many  cases  of  dysmenor- 
rhoea, the  occurrence  might  perhaps  have  been  accepted 
as  an  argument  for  believing  the  dysmenorrhoea  token  to 
be  a  part  of  a  general  rheumatic  process.  But,  though 
the  conjunction  was  reported  in  seven,  it  was  conspicu- 
ously absent  in  as  many  cases ;  and  these  are  precisely 
the  instances  which  do  most  to  prove  that  the  arthritis  is 
a  product  of  the  uterine  hyperaemia.  With  this  simple 
question,  we  will  deal  for  a  moment,  leaving  the  modus 
operandi  to  be  discussed  later  on. 

Among  the  seven  cases  referred  to  as  not  accompanied 
by  dysmenorrhoea  was  that  of  a  lady  then  fifty-two  years 
of  age.  She  had  had  a  large  family — ^in  all  twelve— and 
it  was  then  as  much  as  five  years  since  she  first  began  to 
suffer  from  arthritis.  Before  the  arthritis  troubled  her, 
she  had  begun  to  experience  excessive  menstrual  loss. 
She  consulted  for  this  a  distinguished  gynaecologist,  who 
found  the  uterus  enormously  engorged,  but  otherwise 
free  from  disease.  The  engorgement  was  lessened  by 
treatment,  but  not  by  any  means  cured,  and  the  menor- 
rhagia  went  on.  The  arthritis  first  came  in  the  form  of 
sharp  inflammation  and  swelling  of  the  knuckles  of  both 
hands,  rendering  them  completely  useless.  It  began 
usually  on  the  second  or  third  day  of  the  menstrual  flow, 
and  continued  as  lofig  after  its  cessation.  The  periods 
becoming  more  frequent  and  lasting  longer  as  time  went 
on,  she  became  reduced  to  a  very  pitiable  state.  She 
was  anssmic,  exceedingly  feeble,  was  crippled  in  hands, 
wrists,  and  knees,  and  lost  her  rest  by  reason  of  what 
she  called  "  fidgets,"  uneasy  but  indefinable  sensations  in 
her  limbs  and  abdomen,  unaccompanied  by  pain  or 
spasm. 

Change  of  air  and  of  scene,  baths,  tonics,  alteratives, 
were  all  used  in  addition  to  local  remedies,  but  no  relief 
was  obtained  till,  as  she  reached  the  age  of  fifty  years, 
the  periods  began  to  be  less  frequent. 

At  length,  intervals  of  two  or  three  months  occurred, 
and  allowed  her  to  gain  st)rength,  when  she  lost  her  ar- 
thritis and  her  fidgets,  and  appeared  perfectly  healtiiy. 
Of  late,  the  periods  had  been  still  further  apart ;  but 
still,  whenever  the  catamenia  appeared,  she  was  once 
more  crippled. 

The  association  of  the  arthritis  with  this  painless  men- 
orrhagia began  clearly  at  a  time  when  the  patient  was 
weakened  and  drained  of  blood.  The  fidgets  illustrated 
the  irritability  of  the  spinal  cord  related  with  imperfect 
nutrition,  and  the  arthritis  came  out  as  a  resultant  of  two 
conditions — uterine  irritation  and  spinal  sensitiveness. 

I  may  add  that  I  have  seen  this  lady  within  the  last  few 
weeks,  not  as  a  patient;  that  the  catamenia  have  entirely 
ceased  for  three  years  ;  that  she  has  had  no  joint-trouble 
since,  excepting  on  one  occasion,  when  it  occurred  in 
conjunction  with  severe  intestinal  catarrh ;  and  that  she 
is  now  ruddy,  well  nourished,  active,  and  cheerful. 

A  lady,  aged  fifty-one,  the  mother  of  six  children, 
came  to  me  in  1882  with  a  gouty-looking  inflammation 
in  the  elbows,  wrists,  hands,  and  knees.  This  had  oc- 
curred a  day  after  the  return  of  the  catamenia,  previously 
absent  for  twelve  months.  She  had  no  signs  of  gout  in 
the  shape  of  deposits,  and  her  own  expression  was,  that 
she  felt  the  attack  to  be  really  **  in  the  nerves."  The 
period  was  short,  and  the  arthritis  disappeared.  But  the 
catamenia  having  since  returned  with  unusual  freedom 
and  duration  on  two  occasions,  she  had  each  time  had 
the  arthritis  severely  enough  to  cripple  her.  The  arthri- 
tis came  on  at  the  end  of  the  periods,  the  last  of  which 
was  accompanied  by  abdominal  pain,  a  circumstance 
hitherto  unknown  to  her.  I  am  now  able  to  repprt  of 
this  case  that  the  catamenia  have  ceased,  and  that  the 
joint-affection  is  forgotten. 


August  30,  1884.] 


THE  MEDICAL  RECORD. 


229 


I  might  multiply  my  citation  to  a  large  extent,  for  the 
idadon  is  illustrated  constantly  now  that  it  has  once 
been  recognized. 

Hypothesis  of  reflex  causation  of  arthritis  by  uterine 
irritatiotL — The  argument  which  was  founded  upon  these 
cases  and  others  not  now  quoted,  had  the  following 
general  bearing :  that,  seeing  this  frequent  coexistence  of 
ji  certain  kind  of  inflammation  of  the  joints  with  uterine 
byperaemia,  seeing  also  that  the  joint-inflammation  in- 
cKBsed  in  intensity  in  a  very  marked  proportion  to  in- 
aease  of  the  uterine  hyperaemia,  and  that,  also,  when  the 
signs  of  uterine  hyperaemia  ceased  the  joint-aflection 
passed  away,  there  was  reason  to  regard  the  one  as  caused 
by  the  other.  The  joint-aflection  had  in  itself  no  neces- 
saiy  property  of  permanency.  The  uterine  affection  had 
of  a  necessity  a  beginning  and  an  end,  and  the  joint- 
affection  was  noticed  only  during  its  existence.  If,  from 
sach  considerations,  it  was  fair  to  infer  that  the  dystrophy 
of  joints  was,  in  some  way,  brought  about  by  an  abnor- 
mal condition  of  the  uterus,  the  intermediate  conditions 
linking  the  two  had  next  to  be  sought  for.  That  there 
vas  some  intimate  relation  between  inflammation  of  the 
joints  and  uterine  conditions  more  or  less  approaching 
inflammation,  had  not  escaped  the  acute  observation  of 
the  late  Dr.  Todd.  In  his  Croonian  lectures  for  the  year 
1843,  he  had  written  :  '*  It  is  remarkable  how  frequently 
diis  afi^ection  "•  (the  symmetrical  nodosities  of  the  hands, 
called  by  him  "chronic  rheumatism  of  joints")  "occurs 
in  women,  and  how  rarely  in  men ;  and  there  are  many 
facts  which  indicate  that,  in  the  former,  it  may  have  an 
uterine  origin,  either  connected  with  the  puerperal  state, 
or  from  a  defective  or  difficult  catameniad  action."  He 
was  inclined  to  believe  that  ''  the  unhealthy  secretions  of 
the  Qterus  afforcis  material  for  the  production  of  rheu- 
matic matter.*'  In  these  lectures  he  quotes  Sir  Heniy 
Holland,  Sir  Charles  Locock,  and  Dr.  Rigby  as  authon- 
ties  m  favor  of  the  opinion  that  there  is  some  connection 
between  the  sexual  functions  and  the  causes  and  course 
of  gout  and  rheumatism. 

Another  good  observer,  Dr.  Fuller,  had  spoken  decid- 
edly as  to  the  fact,  that  ^*  rheumatic  gout  attacks  women 
rather  than  men."  *<  It  fixes,''  he  had  said,  '^  upon  the 
girl  JQst  arriving  at  puberty,  whose  menstrual  functions 
are  ill  performed,  and  it  occurs  frequently  at  the  cessa- 
tion of  menstruation  or  during  the  debility  which  follows 
on  a  miscarriage,  or  a  difficult  or  protracted  labor,  more 
generally  when  complicated  by  floodmg."  These  authors 
Ibond  die  explanation  of  the  relation  which  they  so 
closely  acknowledged  in  the  suggestion  of  a  virus,  gen- 
erated in  the  uterus,  absorbed  by  the  blood,  and  attack- 
ing, in  virtue  of  some  elective  affinity,  the  joints. 

If  we  consider  the  many  cases  in  which  acute  rheuma- 
tism occurs  immediately  after  parturition,  in  the  early 
weeks  of  lactation,  we  may  acknowledge  that  the  se- 
quence of  morbid  phenomena  lends  much  support  to  a 
hypothesis  of  this  kind.  We  must  acknowledge  that  the 
condition  of  the  uterus  after  parturition  provides  a  large 
quantity  of  septic,  inflammatory,  and  quasi-inflammatory 
matters ;  that  its  vascular  arrangements  are  such  as  to 
offer  a  ready  access  of  these  matters  to  the  circulation  ; ' 
and  that  where  these  matters  are  undoubtedly  septic  and 
where  they  find  access  to  the  circulation,  in  the  septicae- 
mia or  pyaemia  which  follows,  the  joints  are  among  the 
organs  most  frequently  invaded  by  the  poison  so  mtro- 
daced  into  the  system.  But  in  this,  as  in  other  forms, 
Ae  joints  are  by  no  means  the  only  subjects  of  attack. 
The  viscera  are,  at  least  with  equal  frequency,  the  seat 
of  this  secondary  affection.  In  the  acute  rheumatism 
associated  with  the  conditions  just  mentioned,  the  serous 
membranes,  and  the  lungs,  and  the  veins,  are  frequent 
sufferers  from  the  inflammation  which  primarily  attacks 
the  jomts  ;  but  they  are  more  rarely  affected  without  in- 
tercurrence  of  a  joint-affection,  although,  in  pyaemia,  it 
is  certainly  not  rare  to  And  the  joints  spared,  while  the 

viscera  show  fatal  lesions.     In  the  nodosity  of  the  joints, 

which  I  have  presented  to  you  as  simultaneous  with,  and 


in  its  variations  parallel  with,  uterine  hyperaemia,  there 
is,  so  far  as  I  have  been  able  to  make  out,  no  correspond- 
ing visceral  inflammation  of  either  an  acute  or  chronic 
kind.  If  a  blood-condition,  having  some  quality  of  at- 
tenuated septicity,  were  the  agent,  the  viscera  ought  in 
fairness  to  ^are  in  the  injury.  We  may  remember  that 
the  presence  of  lactic  acid  in  the  blood  has  been  ad- 
duced in  explanation  of  the  phenomena  of  acute  rheu- 
matism, and,  perhaps,  more  particularly  of  acute  rheu- 
matism breaking  out  during  lactation.  This  very  neat 
hypothesis  has  been  supported  by  names  of  great  au- 
thority, and  rests  on  the  observations  that  the  adminis- 
trations of  lactic  acid  to  men  and  animals  is  followed  by 
joint-affection,  and  that  lactic  acid  has  been  found  in  the 
blood  during  acute  rheumatism.  The  whole  theory  rest- 
ing on  these  somewhat  slender  bases  cannot,  I  think, 
apply  in  any  way  to  the  joint-affections  considered  in  the 
early  part  of  this  address,  where  the  only  obvious  lines 
of  causation  were  nervous. 

There  are  not  a  few  considerations  which  induce  me 
to  oppose  to  this  humoral  and  chemical  view  the  view  of 
nerve-agency.  Putting  aside  those  peculiarities  of  per- 
sonal constitution  which  render  certain  persons  prone, 
under  many  circumstances  involving  febrility,  to  develop 
joint-affection,  particularly  acute  rheumatism,  I  would 
represent  that  at  least  a  very  large  majority  of  the  women 
having  nodosity  of  the  joints,  or  arthritis  deformans,  pre- 
sent in  the  first  place  a  marked  hyperaemia  of  the  os  and 
cervix  uteri.  That  these  organs  have  the  power,  through 
centripetal  nervous  influence,  of  producing  enormous  ex- 
citement in  the  spinal  cord  is  the  next  point  which  may  be 
taken.  Sometimes  the  excitement  may  show  itself  by  pains 
in  the  limbs,  sometimes  by  flushings  of  the  skin,  sometimes 
by  swellings  of  the  breasts.  Sometimes,  as  it  appears  to  me, 
the  effects  of  excitement  may  be  reflected  along  the  same 
paths,  which  in  primary  affection  of  the  spinal  cord  have 
led  to  affections  of  joints.  Moreover,  the  state  of  the 
patients  under  consideration  is  generally  one  of  debility, 
often  one  of  anaemia.  It  is  a  matter  of  daily  experience 
that  in  such  conditions  the  reflex  excitability  of  the 
spinal  cord  is  increased ;  it  explodes,  so  to  speak,  on  the 
application  of  impulses  which,  in  its  proper  nutrition,  it 
would  transmit.  And  so  both  the  local  and  the  general 
state  would  conduce  to  the  reflection. 

Gonorrhceai  rheumatism. — ^There  is  yet  another  form  of 
arthritis  in  which  it  appears  to  me  possible  to  call  in  the 
agency  of  the  nervous  system.  I  speak  of  gonorrhoea!  rheu- 
matism, so  called.  In  this  disease,  as  we  know,  an  arthritis 
having  no  differences  in  its  local  morbid  anatomy  from  the 
lesions  already  discussed  comes  on  during  an  attack  of 
gonorrhoea,  often  in  company  with  ophthalmia  or  sclero- 
titis. When  the  gonorrhoea  ceases  the  joint  usually  gets 
well.  The  arthritis  is  easily  induced  afresh  by  new  at- 
tacks of  gonorrhoea.  There  are,  however,  some  varia- 
tions in  progress  and  relation.  The  arthritis  sometimes 
coincides  with,  sometimes  alternates  with,  the  gonorrhoeal 
flow.  It  sometimes  persists,  particularly  in  the  knees 
and  ankles,  producing  chronic  dxanges  leading  to  '<  white 
swelling,"  or  a  kind  of  anchylosis.  The  affection  is  only 
seen  in  males.  Ricord  gave  it  the  name  of  '*  blennor- 
rhagic  arthritis,"  whicli  is  to  my  mind  a  far  better  term 
than  gonorrhoeal  rheumatism.  As  regards  its  diagnosis, 
he  asserted  that  the  only  real  difference  between  this 
form  of  arthritis  and  all  the  others  is  to  be  found  in  the 
cause  which  gives  rise  to  it.  Brodie,  EUiotson,  Fuller, 
and  others,  have  cited  cases  in  which  a  simple,  that  is  to 
say,  not  gonorrhoeal,  urethritis  has  had  associated  with  it 
the  same  three  disorders — arthritis,  conjunctivitis,  sclero- 
titis. It  is  hard,  of  course,  to  prove  a  negative,  but  we 
have  the  evidence  of  the  above-named  excellent  ob- 
servers, that  they  at  least  accepted,  in  these  cases,  the 
absence  of  gonorrhoeal  taint  as  a  fact 

I  have  seen  lately  a  gentleman  suffering  from  a  third 
attack  of  the  kind.  He  is  gouty,  lives  temperately,  but 
works  very  hard.  On  three  occasions  he  has  had  severe 
purulent  urethritis,  which  he  asserts,  to  be  absolutely  un- 


230 


THE  MEDICAL  RECORD. 


[August  30,  1884. 


connected  with  any  possible  source  of  gonorrhoea!  kind. 
This  is  followed  by  sharp  arthritis,  and  sometimes  by 
gouty  inflammation  of  the  toe,  lasting  until  the  discharge^ 
which  is  very  obstinate  in  resisting  treatment,  is  checked. 
The  patient  is  a  man  of  the  world,  and  I  believe  his 
statement.  His  own  belief  is  that  all  the  phenomena  are 
gouty. 

Blennorrhagic  arthritis  has  naturally  been  attributed  to 
some  specific  infection  of  the  system  from  the  urethra, 
and  consequent  infection  of  the  joints  ;  but  if  the  con- 
ciurence  of  a  similar  arthritis  with  non-specific  urethritis 
be  admitted,  the  theory  of  a  specific  poisoning  is  con- 
siderably weakened.  If  it  be  acknowledged,  again,  that 
so-called  gonorrhoea!  rheumatism  is  a  disease  only  seen  in 
men,  the  difficulty  of  accepting  the  specific  idea  is  in- 
creased. 

Women  certainly  do  suffer  from  gonorrhoea,  and  I  can 
conceive  no  reason  why,  if  they  have  it,  they  should  not 
be  poisoned  by  it  in  the  same  way  as  men  are.  The 
more  I  think  over  the  matter,  the  more  do  I  see  to  sug- 
gest a  parallel  between  the  nodosity  of  the  joints  m 
women,  so  often  associated  with  irritation  of  the  uterine 
surfaces,  and  the  blennorrhagic  arthritis  associated  in 
men  with  inflammation  of  the  urethral  surface,  particu* 
larly  if  the  prostatic  part  of  the  urethra  be  affected. 
That  excitements  of  the  prostatic  part  of  the  urethra, 
particularly  of  the  floor,  have  enormous  influence  upon 
the  spinal  cord,  is  shown  by  the  phenomena  of  sexual 
intercourse.  The  widespread  indescribable  sensations 
which  attend  emission,  and  the  exhaustion  which  follows, 
testify  to  this.  Most  of  us  have,  no  doubt,  been  con- 
sulted by  men,  chaste  in  act,  who  are  tormented  by 
sexual  excitement.  They  tell  one  stories  of  long  con- 
tinued local  excitement,  followed  by,  intense  muscular 
weariness,  or  by  some  severe  aching  pain  in  the  back 
and  legs.  In  some,  I  have  had  complaint  of  swelling 
and  stiffness  in  the  legs,  and  of  pains  in  the  joints,  par- 
ticularly in  the  knees.  Conditions  of  this  kind  indicate 
an  effect  upon  the  spinal  cord  which  is  very  nearly  react- 
ing in  trophic  influence  upon  the  limbs.  I  may  relate  a 
case  in  which  it  seems  to  me  that  an  actual  trophic  in- 
fluence was  exerted. 

A  gentleman,  thirty  years  of  age,  who  had  lost  his  wife 
about  two  years  before,  came  to  me  with  painful  affection 
of  the  knees.  Both  knee-joints  were  greatly  distended 
with  fluid  and  were  tender,  but  not  much  heated.  The 
condition^  reminded  one  of  the  "  arthropathie  des  atax- 
iques ; "  but  no  other  sign  of  tabes  dorsalis  could  be 
detected  then  or  since.  I  tried  various  remedies  without 
success,  and  he  went  to  many  doctors  and  many  baths, 
without  obtaining  a  cure ;  though  at  last  with  some  relief. 
Then  he  married  again.  Not  long  after  he  came  to  tell 
me  that  he  was  quite  well.  He  dso  told  me,  upon  my 
asking  him  as  to  his  bachelor  life,  that  he  had  been  almost 
constanUy  harassed  by  the  thorn  in  the  flesh,  but  that  he 
had  been  absolutely  chaste,  and  he  himself  was  of  opinion 
that  marriage  had  been  the  means  of  cure.  I  hear  of 
late  (some  seven  years  after  the  second  marriage)  that  his 
joints  are  getting  bad  again,  and  at  the  same  time  that 
his  wife  suffers  from  a  uterine  affection  almost  altogether 
preventing  cohabitation.  Upon  such  grounds  as  the  fore- 
going considerations  afford,  I  suggest  it  is  possible  that 
irritation  of  nerve-cells  in  the  spinaJ  cord,  carried  to  them 
through  channels  of  urethral  nerves,  may  set  up  an  excite- 
ment m  those  cells  giving  rise  to  irritative  processes  in 
the  joints  supplied  by  them.  M.  Charcot's  cases  already 
referred  to  indicate  rather  a  process  of  inhibition  than 
anything  else  ;  of  torpor,  as  he  says,  of  the  nerve-cells 
under  centripetal  stimulating  coming  from  joints. 

Urinary  paraplegia. — In  relation  with  the  idea  that 
irritation  is  set  up  in  joints  by  irritation  reflected  firom 
viscera,  I  am  tempted  to  point  to  the  so-called  reflex  or 
urinary  paraplegia  as  illustrating,  possibly,  a  torpor  set 
up  in  the  nerve-cells  of  the  cord  instead  of  an  irritation 
dependent  on  centripetal  irritation  coming  from  viscera. 
The  name  reflex  paraplegia,  given  by  Brown-Sdquard, 


has  been  of  late  replaced  by  a  safer  term — ^urinary  para- 
plegia. But,  whichever  name  we  use,  we  recognize  that 
an  urethral  irritation,  most  commonly  dependent  on  a 
stricture,  is  so  joined  with  paralysis  or  paresb  [of  the 
lower  limbs  as  to  make  it  probable  that  the  stricture  is  a 
cause  of  which  the  paraplegia  is  an  effect  The  objec 
tion — a  just  one — to  the  application  of  the  term  **  reflex" 
lies  in  the  fact  that  the  paralysis  can  sometimes  be  traced 
to  myelitis  in  the  lower  part  of  the  cord,  sometimes  to 
neuritis.  But  in  a  certain  number  of  cases  no  lesion  of 
cord  or  nerves  has  been  detected,  and  to  such  cases, 
where  the  paraplegia  and  the  urethral  irritation  were  the 
only  coexistences,  the  term  reflex  might  be  applied.  I 
do  not  speak  here  of  other  reflex  paraplegias.  I  merely 
wish  to  indicate  the  possibility  of  some  such  nerve-relap 
tions  existing  between  the  urethral  surface  of  man  and 
the  joints,  between  the  uterine  surface  of  woman  and 
the  joints,  carried  on  by  the  mediation  of  the  nerves  and 
cord,  and  to  compare  them  with  such  relation  as  we  have 
been  treating  of  as  probably  existing  between  the  joints 
and  muscles  through  the  cord. 

Enough,  you  will  say,  of  the  joints  and  their  neurotic 
dystrophies.  Too  little,  I  reply,  for  time  forbids  me  to 
discuss  the  neurotic  dystrophies  of  gout. 

Neurotic  dystrophies  of  secretion. — I  am  compelled  to 
go  on  to  another  subject,  and  to  direct  your  attention 
to  some  neurotic  dystrophies  of  secretiori!  Some  of  the 
most  striking  of  these  are  certainly  hard  to  be  under- 
stood.  So  far  as  I  am  aware,  it  is  not  known  why  the 
breath  of  a  man,  who  has  undergone  great  and  concen- 
trated mental  anxiety,  should  suddenly  become  fetid ;  or 
why  the  milk  of  a  woman,  whose  emotions  of  fear  or  anger 
have  been  violently  excited,  should  prove  poisonous  to 
the  infant  at  her  breast. 

Glycosuria  in  relation  to  nerve-influence, — Suggestions, 
illustrating  the  mode  in  which  such  dystrophies  come 
about  may  not  unreasonably  be  afforded  from  a  consid- 
eration of  what  is  known  with  regard  to  the  production 
of  glycosuria.  Not  long  ago  I  reviewed  my  notes  of 
cases  of  glycosuria  unattended  by  diuresis ;  such  cases 
occurring  almost  entirely  in  persons  over  fifty  years  of 
age.  Since  the  time  of  Bernard's  great  discovery  a  long 
series  of  experimental  physiologists  has  been  engaged  in 
working  out  the  influence  of  the  higher  centres,  and  of 
the  sympathetic  in  producing  glycosuria.  Pathological 
investigation  has  brought  many  f^ood  observers  to  the 
belief  that  true  diabetes  mellitus  is  caused  by  disease  of 
the  central  nervous  system.  It  must  be  admitted  that 
this  point  is  still  far  from  settled  In  the  non-diabetic 
glycosuria  of  comparatively  old  people,  we  may  see  a 
dystrophy  coexistent  with  disorders  of  various  kinds- 
disorders,  for  the  most  part,  more  pressing  than  itself— 
in  such  relation  that  we  may  be  justified  in  reducing  it  to 
the  rank  of  a  symptom.  If  it  can  be  ref;arded  as  a  symp- 
tom, we  may  have  a  reasonable  probability  of  arriving  at 
a  notion  of  its  causation  by  an  examination  of  its  coinci* 
dences  or  its  coexistences.  As  regards  the  onset  of  true 
diabetes,  the  frequent  antecedence  of  great  emotional 
^disturbance  of  the  central  nervous  system  has  been  recog- 
nized by  general  consent.  Dr.  Dickenson  has  collected 
a  large  number  of  illustrations  of  this  connection  in  his 
work  on  "  Diseases  of  the  Kidneys."  In  the  cases  which 
I  have  analyzed,  one-third  of  the  whole  number  told  a 
story  of  excessive  or  prolonged  mental  work  or  anxiety 
preceding  the  recognition  of  glycosuria. 

In  one,  after  much  emotional  excitement,  insanity  was 
at  last  fully  declared.  In  one,  after  a  long  course  of  stren- 
uous mental  labor,  scarcely  intermitted  during  the  nights 
of  many  years,  hemiplegia  occurred,  and  apoplexy  ended 
the  chapter.  The  last  two  of  these  cases  lead  on  to 
another  group,  in  which  glycosuria  appeared  as  a  symp- 
tom of  actual  disease  of  the  nervous  system. 

In  two  cases  there  was  marked  tabes  dorsalis,  and  in 
a  third  locomotor  ataxy  was  present,  with  additional 
signs  indicating  affection  of  the  whole  breadth  of  the  spi- 
nal cord.     Decided  hypochondriasis  was  noted  in  two 


August  30,  1884.] 


THE  MEDICAL  RECORD- 


231 


cases.  One  of  the  patients  was  haunted  by  the  dread  of^ 
sjphilidc  disease,  but  manifested  no  signs  thereof  what- 
ever. In  a  third  group  marked  signs  of  nervous  disor- 
der accompanied  the  glycosuria^  to  wit,  tinnitus,  vertigo, 
sleeplessness  in  an  extreme  d^;ree,  constant  headache, 
loss  of  power,  of  thought,  and  memory,  numbness  in 
limbfy  sciatica,  shingles,  prurigo,  and  marked  loss  of  mus 
colar  eneigy.  In  &ee  cases  the  patients  were  the  sub- 
jects of  a  very  typical  form  of  angina  pectoris.  I  may 
add  that  I  have  since  seen  another  illustration  of  this  co- 
exjstence.  To  sum  up,  there  was  scarcely  a  case  in  which 
gI)?C05aria  was  not  associated  either  with  evident  disease 
of  the  central  nervous  system,  or  with  symptoms  indicat- 
ing great  perturbation  of  the  centres  of  the  nerves.  A 
second  stage  of  observation  brings  out  a  new  set  of  rela- 
tioos.  In  more  than  a  third  of  the  cases  true  gout  was 
disdncdy  present ;  in  a  much  smaller  number  chronic 
liienmatoid  arthritis.  A  third  of  the  patients  admitted 
habitual  over-indulgence  in  alcoholic  stimulants. 

The  multiform  relations  of  glycosuria  here  exhibited 
would  lead  to  the  inference  that  the  ultimate  causes  are 
of  many  kinds.  We  may  recognize  the  excess  of  sugar 
in  the  blood  giving  rise  to  glycosuria  as  having  at  least 
a  sixfold  origin.  Putting  aside  causes  consisting  in  dis- 
proportion between  the  amount  of  saccharine  matter  in- 
troduced into  the  system,  and  the  capacity  of  the  liver 
for  transforming  it,  or  in  varying  stability  of  glycogen,  or 
io  diminished  use  of  sugar  by  the  system,  we  come  to  the 
discussion  of  the  increased  decomposition  of  glycogen 
detennined  by  increased  afflux  of  diastatic  ferment.  To 
pat  this  in  other  words,  we  come  to  the  consideration  of 
dilatation  of  the  hepatic  artery  and  its  branches  allowing 
of  an  increased  inflow  of  ferment-containing  blood.  By 
sach  kind  of  intermediate  influence  it  is  probable  that 
inritations  and  irritability  of  the  nervous  system  can  be 
conceived  to  set  up  the  glycosuria.  Irritation  of  the 
hepatic  nerves  in  alcoholism  and  diseases  of  the  liver, 
irritation  of  the  pneuraogastric  in  the  stomach  or  in  the 
heart,  irritations  of  the  pneumogastric  arising  in  other 
peripheric  stimulation  can  conceivably  be  reflected  in 
t  pathological  way,  as  they  are  known  to  be  in  a  physio- 
logical way ;  and  in  the  most  typical  of  the  cases  which 
I  have  analyzed  I  have  had  presented  to  me  as  causa* 
tire  of  glycosuria  at  the  same  time  signs  of  deep  gastric 
(T  hepatic  disorder,  and  signs  of  general  nervous  irrita- 
hilitj. 

Gwf  and  glycosuria, — Gout  and  glycosuria  have  been 
seen  in  tolerably  frequent  association  in  my  cases.  Dr. 
Gairdner  pointed  this  out  many  years  ago.  Dr.  Lauder 
Brunton  has  used  the  term  gouty  glycosuria.  I  am 
tempted,  after  much  thinking,  to  ask  whether  the  expres- 
sioD  "  gout  of  the  liver  "  may  not  be  appropriate  ;  to  ask 
whether  we  may  not  entertain  the  idea  that,  in  many 
people,  there  may  exist  a  more  or  less  constant  Arterial 
hyperemia  of  the  liver,  comparable  to  the  acute  hyper- 
emia of  joints,  undoubtedly  an  essential  factor  of  acute 

Acute  inflampuiiion  of  diabetes  and  nerve-influence. — 
In  true  diabetes  the  occurrence  of  sudden  and  very  acute 
visceral  inflammations  is  common.  It  is  generally  found 
tiuit,  while  such  complications  last,  •  the  urinary  sugar 
dwindles,  or  even  disappears.  An  explanation  of  this 
occurrence  has  been  found  by  some  writers  in  the  hy- 
pothesis of  an  increased  combustion  of  sugar  as  a  part 
of  the  pyrexial  state.  But,  seeing  that  such  inflamma- 
tions involve  the  diversion  of  a  large  quantity  of  blood 
to  the  organ  aflfected,  I  venture  to  suggest  that  in  such 
^ersion,  rather  than  in  a  purely  hypothetical  combus- 
tion, may  be  found  the  true  explanation.  Physiological 
experiment  has  shown  that,  when  sections  of  the  sympa- 
thetic leading  to  vaso-motor  dilatation  of  the  hepatic 
vessels  alone  has  been  made,  glycosuria  has  been  pro- 
duced ;  that,  when  the  section  has  been  made  at  a  point 
producing,  in  addition  to  dilatation  of  the  arteries  of  the 
^er»  dilatation  of  the  vessels  of  the  intestines,  glycosuria 
has  not  followed.     The  inference  drawn  is  to  the  effect 


that  so  much  arterial  relaxation  was  produced  in  the 
supply  of  organs  neighboring  to  the  liver  as  to  stand  in 
the  way  of  an  effective  increase  in  its  arterial  circulation. 
I  had  an  opportunity  quite  recently  of  testing  the  prob- 
ability of  this  hypothesis.  The  temperature  of  a  diabetic 
patient  rose  suddenly  to  104^  Fahr.  The  most  careful 
examination  brought  out  no  signs  of  visceral  inflamma- 
tion during  two  days,  and  in  the  same  period  the  amount 
of  sugar  in  the  urine  stood  at  the  figure  registered  for 
several  weeks  before.  On  the  third  day,  the  tempera- 
ture remaining  at  the  same  height,  the  signs  of  pneumonia 
became  apparent,  and  at  the  same  time  the  urinary  sugar 
diminished  very  considerably.  In  my  gouty  cases  a 
similar  train  of  phenomena  has  been  several  times  noted 
— the  sugar  diminishing  in  a  very  marked  degree  at  the 
time  of  the  development  of  acute  joint-inflammation,  and 
returning  immediately  on  its  subsidence. 

In  trymg  to  understand  the  sudden  acquirement  of  a 
poisonous  quality  by  the  milk  of  an  agitated  woman,  one 
had  found  a  difficulty  of  this  kind— could  mere  quantita- 
tive variations  in  the  afflux  of  blood  affect  the  quality  of 
the  secretion  ?  Can  it  be  possible  that,  in  the  produc- 
tion of  the  lacteal  secretion,  may  be  concerned  not  merely 
increased  afflux  of  the  materials  of  the  secretion,  but  also 
varying  afflux  of  ferments  determining  its  quaility,  and 
capable,  by  reason  of  either  great  deficiency  or  ^eat  ex- 
cess, of  seriously  perverting  its  quality  ?  Here  is  an  ad- 
mitted neurotic  dystrophy,  the  mechanism  of  which  is 
well  worth  careful  investigation ;  and  from  the  considera- 
tion of  glycosuria  we  may  be  enabled  to  glean  at  least 
suggestions  as  to  what  the  mechanism  may  be. 

T7i€  nervous  relations  of  myxadema. — Let  me,  leaving 
many  points  which  are  tempting,  go  on  to  say  a  few 
words  about  another  class  of  neurotic  dystrophies,  namely, 
about  those  occurring  in  myxoedema,  occurring  therem 
to  such  an  extent  as  to  constitute  the  predominant 
symptomatology  of  that  disease.  We  may  recognize  in 
myxoedema  three  principal  lines  of  nervous  abnormity. 

Firsty  intellectual,  consisting  in  slowness  of  thought, 
in  slowness  of  volition,  in  loss  of  memory,  in  irritability 
of  temper,  in  unwarranted  suspicions,  in  delusions,  in 
actual  insanity,  or  in  torpor  growing  to  coma. 

Second^  in  sensation.  General  sensation  undergoes  a 
change,  to  which  the  term  bradyaesthesia  is  applicable  ; 
the  recognition  of  impressions  made  on  the  surface  is  dis- 
tinctly retarded ;  the  sensibility  to  sensations  of  heat  or 
cold  is  blunted ;  and  there  are  often  noted  abnormal 
subjective  sensations,  particularly  affecting  the  sense  of 
taste  and  smell. 

Thirds  the  motor  powers  are  disturbed  in  a  singular 
way  ;  all  motion  is  slow ;  co-ordination  is  imperfectly 
adjusted  ;  certain  groups  of  muscles  become  unduly  re* 
laxed,  and  are  stimulated  to  action  only  by  strong  exer- 
cise of  volition.  Reflex  actions  are  produced  with  con- 
siderable delay.  In  some  cases  evidences  of  more 
lo^dized  nervous  impairment  occur,  in  particular  the 
signs  of  bulbar  paralysis.  It  may  be  argued,  on  the  one 
hand,  that  this  remarkable  assemblage  of  nervous  disor- 
ders points  to  the  nervous  system  as  the  seat  of  the 
original  cause  of  the  disease ;  on  the  other,  that  the 
obvious  changes  in  the  state  of  the  connective  tissues 
throughout  the  body  may  affect  the  nervous  centres  and 
put  their  morbid  reactions  into  the  category  of  secondary 
conditions.  It  is  a  question,  that  is  to  say,  whether 
myxoedema  be  a  neurotic  dystrophy,  or  whether  the  dis- 
orders of  the  nervous  system  are  produced  by  an  altera- 
tion of  connective  tissues,  having  an  origin,  like  that  for 
instance  of  lardaceous  disease,  independent  of  nervous 
influence — chemical,  degenerative,  inflammatory,  or  other. 
The  remarkable  atrophy  of  the  thyroid  body  observed  in 
this  disease,  and  the  relation  which  is  by  many  regarded 
as  existing  between  that  body  and  the  sympathetic  sys- 
tem, have  brought  some  thinkers  to  the  belief  that  the 
disease  arises  primarily  neither  in  affections  of  the  cere- 
bro-spinal  system,  nor  in  altered  nutrition  of  the  connec- 
tive tissues.     Those  who  are  induced  to  take  this  view 


232 


THE  MEDICAL  RECORD. 


[August  30,  1884. 


have  found  the  explanation  in  primary  alteration  of  the 
sympathetic  system ;  in  alteration  of  the  sympathetic 
system  somehow  determined  by  the  atrophy  of  the  thyroid, 
or  in  alteration  of  the  sympathetic  system  determined  by 
chronic  apyretic  inflammations  withm  the  chest,  particu- 
larly in  the  pleura.  What  can  be  said  is,  that  in  this 
disease  there  can  be  recognized  an  enormous  dystrophy 
of  connective  tissues ;  that  the  dystrophy  has  certain 
aspects  of  degeneration ;  that,  again,  in  the  increase  of 
nuclei,  it  has  some  aspect  of  over- activity ;  and  that,  so 
far,  it  may  suggest  the  occurrence  of  a  low  form  of  in- 
flammatory process  inducing  degeneration  of  the  tissues 
involved ;  or  that,  on  the  other  hand,  a  degeneration  has 
induced  a  very  elementary  inflammatory  process  in  the 
tissues. 

The  atrophy  of  the  thyroid  may  conceivably  be  brought 
about  by  the  changes  of  the  connective  tissue  which  we 
can  see  in  the  other  parts  of  the  body,  leading,  by  the 
aggressive  hypertrophy  of  that  tissue,  to  pressure  on, 
and  atrophic  changes  in,  immeshed  glandular  tissues. 
But  here  we  must  hold  our  hand,  for  there  is  another  side 
to  the  question.  Kocher  and  others  in  Switzerland  have 
of  late  years  been  cutting  out  enlarged  thyroid  glands, 
and  have  recorded  the  sequence  upon  this  operation  of 
slow  development  of  a  condition  which,  as  produced  and 
described  by  them,  corresponds  exactly  with  myxoedema 
as  observed  in  England.  The  interest  of  the  observation 
is  intensified  by  the  circumstance  that  these  operators  in 
making  this  record  were  not  aware  of  the  observations 
on  myxoedema,  made  in  this  country. 

The  true  function  of  the  thyroid  body  being  undeter- 
mined, one  may  hope  that  the  concurrent  observations 
may  converge  in  such  a  way  as  to  throw  light  on  a  very 
obscure  bit  of  physiology ;  but  it  is  hard  to  resist  the 
conclusion  that,  through  some  nervous  channels,  the 
thyroid  body  influences  the  nutrition  of  the  connective 
tissues  generally,  and  may,  perhaps,  also  influence  the 
nutrition  of  the  cerebro-spinal  centres. 

To  put  the  matter  in  another  way,  the  great  tendency 
of  existing  observations  is  to  class  myxoedema  among 
neurotic  dystrophies. 

I  should  have  liked,  if  I  could  have  brought  them 
within  the  compass  of  this  address,  to  have  said  some- 
thing about  the  neurotic  dystrophies  of  the  skin,  but 
must,  however,  reluctantly  leave  them  untouched. 

Many  here  will  think  that  I  should  have  said  something 
about  the  dystrophies  incited  by  surgical  injuries  of 
nerves.  These  last,  indeed,  ofler  possibilities  of  more 
exact  treatment  than  any  of  the  dystrophies  which  have 
engaged  our  attention.  The  observations  of  Weir 
Mitchell,  Brown-S6quard,  Hutchinson,  and  others  have 
been,  in  some  unconscious  fashion,  directing  my  thoughts 
to  the  choice  of  the  subject  of  to-day's  address.  Let  me 
acknowledge  this  fully ;  and  let  me  ask  you  to  under- 
stand that  I  have  to-day  merely  been  putting  before  you 
the  result  of  observation  and  thought  set  going  by  the 
reading  of  the  works  of  predecessors  and  contemporariAu 
Each  succeeding  generation  in  science  gathers  the  lines 
of  older  and  recent  vision  into  some  focus  more  or  less 
of  its  own  choosing.  The  wisdom  of  the  choice  is  to  be 
judged  by  the  generations  still  succeeding.  What  shall 
be  the  outcome  here  ? 


A  Rare  Human  Tapeworm. — Dr.  Leidy  describes 
in  The  American  Journal  of  the  Medical  Sciences  for  July, 
1884,  the  taenia  flavopunctata,  a  rare  human  tapeworm, 
which  has  now  been  observed  for  a  second  time,  both 
cases  occurring  in  this  country  and  infesting  children. 
It  is  not  improbable  that  the  species  is  more  common 
than  the  observations  would  warrant  us  in  believing,  for 
from  the  smallness  of  the  worm  and  the  generally  pre- 
vailing ignorance  of  the  distinctions  in  the  more  com- 
mon species,  it  might  readily  be  passed  for  immature 
portions  of  these. 


CEREBRAL    LOCALIZATION— THE    CENTRES 
FOR  VISION. 

By  PHILIP  ZENNER,  A.M.,  M.D., 

aMaKNATI,  o. 

(Condnued  from  page  149.)  1 

Physiological  //«/<».— Fritsch  and  Hitzig,  in  1870,  first 
made  known  to  the  world  that  irritation  or  removal  of 
certain  parts  of  the  cerebral  cortex  was  followed  by  defi. 
nite  motor  phenomena,  or  the  disturbance  of  the  cere- 
bral functions.  Their  experiments  made  it  highly  prob- 
able that  different  parts  of  the  cortex  have  different  and 
distinct  functions.  Their  results  were  soon  corroborated 
'  and  extended  by  Ferrier,  and  since  then  there  have  been 
numerous  contributions  of  the  same  kind. 

Experiments  of  Munk. — It  is  not  my  object  to  enter 
into  any  historical  disquisition,  but  rather  to  give  those  ex- 
perimental researches  which  bear  directly  on  our  subject 
I  shall,  therefore,  begin  immediately  with  the  experiments 
of  Munk,  which,  from  the  precision  and  completeness  of 
their  results,  have  excited  universal  admiration.  We  will 
consider  them  only  so  far  as  they  are  concerned  with  the 
sense  of  vision. 

Munk's  experiments  were  made  upon  dogs  and  mon- 
keys, chiefly  the  former.  The  conclusions  drawn  from 
them  were  :  i,  in  the  dog  the  visual  centre  is  in  the 
occipital  region,  the  visual  area  of  each  hemisphere  be- 
ing in  relation  with  both  eyes,  though  to  a  much  greater 
extent  with  the  eye  on  the  opposite  side  than  with  the 
one  on  the  same  side ;  2,  in  the  monkey  the  visual  centre 
is  in  the  occipital  lobe,  one  hemisphere  being  in  relation 
with  one-half  of  each  retina. 

Munk  reported  his  results  at  various  meetings  of  the 
Physiological  Society  of  Berlin,  in  the  years  1877-80. 
Each  successive  report  contains  the  additional  knowledge 
gained  from  his  latest  experiments,  and  becomes  espe- 
cially interesting  on  account  of  the  manner  in  whidi 
former  statements  are  amplified  or  corrected.  There  is 
something  in  the  gradual  development  of  his  views  whidi 
apparently  adds  to  their  weight,  and  the  more  easily  con- 
vinces us  of  their  correctness.  In  order  to  give  a  better 
idea  of  these  admirable  experiments,  I  will  give  a  brief 
summary  of  his  reports : ' 

He  began  by  removing  small  circular  segments,  fifteen 
millimetres  in  diameter  and  about  two  millimetres  in  depth 
from  the  convexity  of  the  brain  (of  dogs)  in  various  local- 
ities. Only  when  the  part  removed  was  in  a  limited 
area  of  the  occipital  region  was  there  any  appreciable 
impairment  of  vision.  When  the  lesion  was  produced  in 
this  region  it  was  followed  by  peculiar  disturbances  of 
sight.  The  affection  of  vision  was  observed  only  in  the 
eye  opposite  to  the  injured  hemisphere.  When  the  sound 
eye  was  covered,  so  that  he  could  only  use  the  affected 
one ;  or,  in  case  a  symmetrical  lesion  had  been  produced 
in  both  hemispheres  when  both  eyes  were  uncovered,  it 
was  observed  that  the  animal  no  longer  recognized  objects 
formerly  familiar  to  him.  Thus,  he  remained  uncon- 
cerned and  quiet  when  a  whip  was  held  before  him,  at 
the  sight  of  which  he  had  previously  been  accustomed  to 
wince  or  run  away.  A  bright  light  brought  suddenly 
before  the  eyes  caused  no  movement,  and  he  remained 
impassive  in  the  presence  of  food  until,  through  some 
other  sense — taste,  smell — ^he  became  cognizant  of  its 
presence.  Yet  the  dog  was  not  blind,  for  he  avoided 
any  obstacle  in  his  way.  At  the  end  of  from  four  to  six 
weeks  this  visual  defect  gradually  disappeared,  and  ob- 
jects were  recognized  as  before. 

Munk  supposed  that  the  removal  of  this  area  in  the 
cortex  did  not  produce  blindness,  but  that  it  robbed  the 
brain  of  that  part  wherein  were  stored  the  visual  images 
gained  from  past  experience,  leaving  the  animals,  there- 
fore, like  new-bom,  who  see,  but  do  not  know  the  mean- 
ing of  what  they  see.  The  fact  that  after  the  lapse  of  a 
few  weeks  they  again  recognized  objects  he  attributed 

>  Taken  from  Functiooen  d«s  GrosshetanDde.  Gewmmrite  Mitthdiimgai.     ; 


August  30,  1884.  J 


THE  MEDICAL  RECORD. 


233 


to  knowledge  gained  from  new  experience.  This  condi- 
tion, in  which  animals,  while  retaining  the  sense  of  vision, 
had  lost  the  knowledge  that  vision  usually  conveys,  he 
tenned  "  soul-bHndncss  "  {seelen  blindheit). 

Later  and  more  careful  observations  revealed  that 
there  was  in  these  instances  not  only  this  mental  blind- 
ness, bnt^  at  least  for  parts  of  the  retinse,  complete  blind- 
ness. It  was  observed  after  the  soul-blindness  had  dis- 
appeared that  when  pieces  of  meat  were  scattered  on  the 
flbor,  the  dog  would  find  some  pieces  and  overlook  others. 
In  hne(  in  those  animals  in  which  the  specified  port  of 
the  cortex  had  been  removed  there  was  absolute  blind- 
ness of  the  central  (the  most  important)  part  of  the  retina 
of  the  opposite  eye,  while  the  peripheral  portions  of  the 
same  retina  remained  intact.  The  size  of  the  blind  spot 
in  the  retina  was  in  proportion  to  the  extent  of  visual  area 
destroyed. 

Munk  now  removed  what  he  supposed  to  be  the  entire 
visual  area  of  one  hemisphere,  the  cortex  of  the  whole 
occipital  region.  At  first  the  animal  made  the  same  im- 
pressions as  those  above  described,  in  the  one  eye  vision 
being  apparently  normal,  in  the  other  the  so-called  soul- 
blin£iess.  Bat  that  this  conclusion  was  not  quite  cor- 
rect was  shown  by  closer  observations.  When  the  sound 
eye  was  covered  objects  held  in  front  of  the  other  were 
apparently  not  seen.  But  if  now  the  object  was  placed 
jost  before  the  covered  eye,  so  that  its  image  fell  on  the 
temporal  side  of  the  retina  of  the  affected  eye  it  then 
seemed  to  be  observed.  Vision  was  retained  in  its  tem- 
poral segment  while  the  rest  of  the  retina  was  paralyzed 
Bot  tiiere  was  for  this  still  sensitive  portion  the  condition 
described  as  soul-blindness — objects  were  seen  but  not 
recognized.  But  the  animal  could  very  readily  be  taught 
to  again  recognize  the  forgotten  objects.  Thus,  when 
food  was  placed  where  its  image  fell  on  the  sensitive  por- 
tion of  the  retina  it  was  at  first  left  untouched.  But  when 
the  animal  learned  what  it  was  firom  his  other  senses,  he 
soon  recognized  it  by  sight  alone.  A  light  held  in  the  same 
position  left  the  animal  unmoved,  but  after  he  had  been 
silked  with  it,  its  mere  appearance  produced  maniies- 
tadoosoffear. 

While  after  entire  removal  of  the  visual  area  of  one 
hemisphere  there  was  thus  partial  blindness  in  the  oppo- 
site eye  (the  larger  part  of  the  retina  being  paralyzed,  a 
smaller  jMurt  on  temporal  side  remaining  sensitive  to  lig^t), 
a  contrary  condition  was  found  in  the  eye  of  the  same 
side.  Here  central  vision  was  perfect ;  but  on  careful 
examination  it  was  observed  that  there  was  a  small  seg- 
ment of  the  retina  on  the  nasal  side,  corresponding  m 
sie  to  die  sensitive  portion  of  the  other  retina,  where 
light  was  no  longer  perceived. 

In  seven  dogs  Munk  succeeded  in  removing  the  entire 
visual  area  of  both  sides.  They  all  lived  several  months 
(one  of  them  ax  months)  after  the  operation.  In  all  of 
^em,  while  the  other  senses  and  power  of  movement  re- 
mained unimpaired,  the  sense  of  vision  was  lost  in  both 
ejes  completely  and  permanently. 
^There  could  scarcely  be  a  more  complete  demonstra- 
tion of  the  cortical  centres  for  vision  than  these  admirable 
experiments  of  Munk.  It  only  remains  to  point  out 
more  precisely  the  relations  of  the  retina  to  the  visual 
area.  This  Munk  succeeded  in  doing'  with  a  wonderful 
degree  of  precision.  His  results  are  as  follows :  The 
outer  part  of  the  visual  area  (about  one-third  of  entire 
visual  area)  is  in  relation  with  the  outer  or  temporal  part 
of  retina  (about  one-fourth  entire  retina)  of  the  same  side. 
The  larger  inner  and  median  part  of  the  visual  area  is  in 
relation  with  the  larger  inner  and  central  part  of  the 
retina  of  the  opposite  side.  The  outer  segment  of  the 
visual  area  is  in  relation  with  the  corresponding  outer 
segment  of  the  retina  in  such  a  way  that  the  inner  part 
of  the  former  is  in  relation  to  the  inner  part  of  the  latter, 
the  outer  part  in  relation  to  the  outer  part  of  the  latter. 
The  same  relationship  exists  between  the  other  corre- 
sponding segments,  that  is,  the  outer  part  of  the  inner 
aod  median  segment  of  the  visual  area  is  in  relation  with 


the  outer  part  of  the  corresponding  inner  and  central 
segment  of  the  retina,  and,  again,  the  inner  part  of  the 
one  in  relation  to  the  inner  part  of  the  other.  To  com- 
plete this  topographical  relationship,  it  need  only  be 
added  that  the  anterior  parts  of  the  visual  area  are  in  re- 
lation with  the  superior,  the  posterior  in  relation  with  the 
inferior  portions  of  the  retina. 

Lest  die  above  may  not  be  altogether  clear,  I  will  re- 
peat the  description  of  relationship  of  cortex  and  retina  in 
Munk's  own  words  :  ^  Each  retina  in  its  outer  lateral 
part  is  devoted  to  the  most  external  lateral  portion  of 
the  visual  area  of  the  same  side.  The  much  larger  re- 
maining part  of  each  retina  belongs  to  the  much  larger 
remaining  portion  of  the  opposite  visual  area,  and  in  such 
a  way  that  we  may  imagine  the  retina  projected  upon  the 
visual  area  with  the  lateral  border  of  diis  larger  segment 
of  the  retina  corresponding  to  the  lateral  border  of  the 
larger  segment  of  the  visual  area,  its  most  internal  border 
to  the  median  border  of  the  latter,  and,  finally,  the  supe- 
rior border  of  the  retina  to  the  anterior,  the  inferior  to 
the  posterior  border  of  the  visual  area." 

The  results  of  Munk's  experiments  on  monkeys  have 
already  been  mentioned.  They  were  made  on  a  smaller 
number  of  animals,  and  lead  to  the  general  conclusion 
that  the  visual  area  is  seated  in  the  occipital  convolutions, 
each  occipital  lobe  being  in  relation  with  a  correspond- 
ing half  of  each  retina.  We  thus  see  that  in  the  monkey 
the  occipital  lobe  is  in  relation  with  a  larger  segment  of 
the  retina  on  the  same  side  than  in  the  dog,  and  in  this 
respect  is  similar  to  what  we  will  have  occasion  to  ob- 
serve in  man. 

These,  then,  very  briefly  given,  are  the  results  of 
Munk's  experiments  on  dogs  and  monkeys.  Ganser^  ob- 
served, after  removal  of  the  occipital  region  in  cats, 
blindness  on  the  corresponding  side  of  both  retinae.  The 
results  obtained  by  other  experimenters,  especially  Fer- 
rier,  will  be  mentioned  at  a  later  period ;  but  we  must 
now  proceed  to  examine  the  experiments  of  an  eminent 
physiologist,  Goltz,  who  has  apparently  obtained  results 
contradictory  to  diose  just  mentioned,  and  who  has  suc- 
ceeded in  exciting  much  doubt  as  to  the  correctness  of 
the  present  theories  of  localization. 

Experiments  of  Goltz. — Goltz  has  made  various  re- 
ports of  his  experiments,  but  of  his  original  contributions 
only  one^  that  published  in  the  first  volume  of  the 
'<  Transactions ''  of  the  last  International  Medical  Con- 
gress, is  at  my  disposal.  The  statements  here  made  are 
taken  diiefly  from  that  article*  A  lew  of  his  experiments 
mentioned  by  Wernicke,'  not  included  in  the  above  re- 
port, will  be  added.  Goltz*  general  conclusions  are  : 
Destruction  of  a  large  part  of  the  cerebral  cortex  weak- 
ens all  its  higher  functions^  it  diminishes  the  intelli- 
gence and  thereby  the  acuity  of  all  the  special  senses. 
But  the  destruction  of  no  part  is  followed  by  the  com- 
plete or  permanent  loss  of  any  cerebral  function,  with 
slight  modifications  all  being  always  alike  affected,  the 
degree  depending  only  on  the  extent  of  the  injury.  In 
other  words,  we  cannot  say  of  any  part  that  it  is  the 
centre  for  vision,  hearing,  the  innervation  of  certain 
groups  of  muscles,  or  the  like. 

The  experiments  were  made  on  dogs.  In  the  begin- 
ning he  was  accustomed  to  remove  portions  of  the  brain 
substance  by  means  of  a  stream  of  water,  large  parts  be- 
ing washed  out  at  one  time.  He  observed,  after  thus  re- 
moving a  large  part  of  one  hemisphere,  hemiplegia  on 
the  opposite  side,  and  blindness  in  the  opposite  eye. 
But  these  symptoms  were  only  transitory.  Soon  the  ani- 
mal appeared  to  use  one  side  as  well  as  the  other ;  and 
the  eye  again  saw,  though  certain  disturbances  remained. 
Altliuugh  he  avoided  obstacles  in  his  way,  he  no  longer 
recognized  persons,  was  not  frightened  when  threatened 
with  a  whip,  etc.;  in  short,  the  condition  above  described 
as  soul-blindness.  Goltz  at  the  same  time  observed 
similar  defects  of  the  other  special  senses.     The  dog  ap- 

*  Archiv  f.  Psychiatrie,  Bd.  xiii.,  1882. 

^  Gchimkrankheiten.    Introduction  to  voU.ii* 


^34 


THE   MEDICAL  RECORD. 


[August  30,  1884. 


parently  retained  the  sense  of  hearing,  but  was  not 
frightened  at  the  cracking  of  a  whip  as  before,  etc  In- 
asmuch as  the  symptoms  were  much  alike,  whatever 
part  of  the  brain  was  washed  out,  Goltz  believed  that 
the  present  theories  of  localization  must  be  incorrect 
But  for  the  purpose  of  examining  the  question  more 
carefully,  he  instituted  another  series  of  experiments, 
wherein,  instead  of  removing  brain  substance  by  means 
of  a  stream  of  water,  he  employed  a  boring-machine, 
wherewith  he  was  enabled  to  remove  much  more  circum- 
scribed parts. 

His  general  conclusions  are  tlie  same  here  as  from 
the  former  series  of  experiments.  From  small  lesions 
he  observed  no  permanent  injury  of  intelligence  or 
special  senses,  from  large  lesions  (and  such  were  pro- 
duced in  most  instances)  the  general  results  already  men- 
tioned In  confirmation  of  his  views  he  exhibited  before 
the^International  Congress  in  London  a  dog  in  whom  he 
had  removed,  at  five  different  periods,  from  November 
15,  1880,  to  May  25,  1881,  large  portions  from  the  pa- 
rietal and  occipital  regions  of  both  hemispheres.  This 
dog  could  run  along  in  a  lively  manner,  revealing  no 
evidence  of  paralysis  of  any  muscles  further  than  a  cer- 
tain awkwardness  in  some  of  his  movements.  He  was  not 
blind,  as  evinced  by  his  avoiding  obstacles.  But  he  mani- 
fested no  fear  when  threatened  with  the  fist  or  whip,  or 
when  a  fiame  was  brought  in  front  of  his  eyes.  He  could 
hear,  for  he  turned  his  head  when  called  and  tried  to 
reach  the  caller.  But  he  heard  unmoved  the  cracking 
of  a  whip,  which  formerly  produced  the  liveliest  mani- 
festations of  fear.  He  could  smell,  but  did  not  object 
to  tobacco  smoke  or  chloroform  vapor.  He  could  taste, 
but  would  eat  the  flesh  of  a  dog,  formerly  very  objec- 
tionable to  him.  Finally,  his  cutaneous  sensibility  was 
retained,  though  blunted.  The  dog's  intellect  was  greatly 
impaired,  and  Goltz  attributed  the  various  sensory  dis- 
turbances just  detailed  to  the  great  lack  of  intelligence. 

It  is  on  experiments  and  observations  of  this  kind  that 
Goltz  bases  his  views.  Yet,  when  properly  considered, 
they  by  no  means  have  the  full  significance  he  attaches 
to  them.'  My  present  remarks  refer  to  his  conclusions 
only  on  the  subject  of  vision.  As  to  the  motor  phe- 
nomena in  these  instances,  they  must  be  explained  in 
quite  a  different  manner.' 

According  to  the  experiments  of  Munk,  the  extirpa- 
tion of  parts  of  the  visual  area  is  attended  by  permanent 
defects  of  vision,  which  defects  are  only  detected  after 
very  careful  observations.  That  Goltz  made  special  ex- 
aminations for  the  purpose  of  discovering  whether  such 
defects  were  present,  whether  there  were  larger  or  smaller 
blind  spots  in  the  retinae,  does  not  appear  from  his  report. 
If  but  a  small  part  of  the  visual  area  remained,  that  would 
probably  be  accompanied  by  sufficient  vision  to  avoid 
obstacles,  etc.,  which  appeared  to  be  the  only  evidence  of 
sight  in  Goltz'  animals,  when  large  parts  of  the  brain 
were  removed.  Only  in  case  he  had  removed  the  entire 
visual  area  of  Munk  without  producing  complete  blind- 
ness could  it  be  said  that  Munk's  statements  had  been 
disproven.  It  is  true,  Goltz  claims  to  have  done  this. 
But  we  may  be  allowed  to  doubt  this  statement  (at  least 
so  far  as  Munk's  description  of  the  visual  area  is  con- 
cerned), for  he  speaks  of  the  entire  removal  of  the  visual 
area  of  the  dog  presented  at  thq  International  Congress, 
though  a  large  part  of  it  still  remains. 

But  what  Goltz  dwells  upon  specially,  as  seeming  to 
disprove  former  theories  of  localization,  is  that  in  his  ex- 
periments the  removal  of  the  so-called  visual  centre 
caused  equal  defects  in  the  other  special  senses,  hearing, 
smell,  etc.     As  an  objection  to  the  correctness  of  such 


*  This  gtatement  and  the  following  ones  axe  based  upon  the  knowledge  of  Goltz* 
experunenu  and  conclusbns  as  found  in  the  report  to  die  International  Congress. 
As  m  this  rraort  he  reviews  the  whole  subject,  we  are  po-haps  justified  in  judging 
it  as  it  stands.  If  there  be  anything  in  his  other  contributions  which  apparently 
nullifies  anv  statement  of  mine,  I  regret  that  such  are  not  within  my  reach. 

>  Femer's  explanation  is  probably  a  correct  one,  that  the  lower  the  animal  the 
greater  the  mdependence  of  the  subcortical  centres;  so  that  in  dogs  locomotion  is 
stUl  possible  after  removal  of  the  cortical  oentres  of  motion,  while  in  the  motiker 
and  man,  where  the  hemispheres  havtf  a  far  higher  influence,  soch  mutilation  wiU 
cause  permanent  paralysis. 


reasoning  it  must  be  mentioned  that  in  such  instances 
large  parts  of  the  brain  had  been  removed.  Thus  not 
only  were  parts  of  the  surface  removed,  which  presuma- 
bly belonged  to  other  centres,  but  the  deeper  portions 
of  the  brain  were  extensively  injured,  and  thus  fibres 
severed  passing  to  various  portions  of  the  cortex.  That 
such  lesions  should  be  followed  by  the  impairment  of 
more  than  one  function  is  not  surprising,  but  what  ought 
to  have  been  expected. 

But  apart  from  these  considerations  Goltz'  expeii- 
ments  in  some  instances  are  opposed  to  his  own  views. 
The  following  illustrations  are  taken  from  Wemick^s 
summary  of  Cxoltz'  experiments.'  A  dog,  in  whom  the 
cortex  of  one  occipital  region  was  removed,  five  we^s 
after  the  operation  saw  only  imperfectly  with  the  op- 
posite  eye,  while  no  other  defect  was .  noticeable.  In 
another  instance,  where  portions  were  removed  from  both 
hemispheres,  vision  was  very  imperfect  while  hearing  was 
apparently  normal. 

The  last  instance  I  shall  mention  is  the  dog  presented 
at  the  International  Congress.  This  case  is  the  more 
worthy  of  careful  study  because  not  only  was  it  publicly 
demonstrated,  but  the  post-mortem  examination  was 
made  by  a  commission  of  impartial  judges,  giving  it  the 
value  not  alone  of  individual  but  also  of  general  observa^ 
tion. 

I  believe  in  this  case  there  is  evidence  of  paralysis  of 
parts  of  the  retinae.  The  do^  did  not  fix  objects  with 
his  eyes,  as  is  usual  in  lookmg  at  things ;  when  called 
and  attempting  to  find  the  one  calling  him,  he  moved 
aimlessly  about ;  and  in  moving  about  he  often  struck 
against  objects  on  the  leffc  side,  which  seemed  to  indicate 
blindness  in  the  left  part  of  the  field  of  vision,  and  may 
be  brought  in  direct  relationship  with  the  fact  made  eviv 
dent  both  by  the  written  description  of  the  post-mortem, 
and  by  the  accompanying  plates,  that  the  visual  area  in 
the  right  hemisphere  was  removed  to  a  much  greater  ex- 
tent than  that  in  the  left 

We  have  dwelt  sufficiently  on  the  experiments  of  Goltz. 
If,  notwithstanding  the  eminence  of  the  experimenter,  we 
cannot  accept  his  views,  we  are  influenced  not  alone  by 
the  results  gained  by  other  experimenters,  but  also  by  the 
critical  study  of  his  own  results. 

Topography  of  cerebral  convolutions. — ^Before  leavii^g 
this  part  of  our  subject  I  must  enter  briefly  into  a  few 
anatomical  details.  The  object  of  our  present  investiga- 
tions is  to  .arrive  at  a  knowledge  of  the  functions  of  parts 
of  the  convexity  of  the  brain.  We  have  thus  far  con- 
sidered mainly  the  results  of  experiments  on  animals,  and 
will  have  next  to  study  pathological  changes  in  man. 
But  in  order  that  there  may  be  a  comparison  between 
such  results  we  must  know  that  the  parts  are  anatom- 
ically homologous,  in  order  to  attribute  to  them  like 
functions,  but  in  appearance  this  is  not  the  case.  It 
will  have  been  observed  that  in  reference  to  rabbits, 
cats,  and  dogs,  I  have  spoken  of  the  occipital  region, 
and  in  man  and  monkey  of  the  occipital  lobes  and 
convolutions.  For  the  latter  can  be  distinctly  mapped 
out  in  man  and  the  monkey,  but  not  in  the  other  animals 
mentioned. 

In  most  of  the  higher  mammalia  there  are  to  be  seen 
in  the  convexity  of  each  hembphere  four  longitudinal 
convolutions  which  pass  from  the  anterior  to  the  poste- 
rior part  of  the  brain,  arching  over  the  Sylvian  fissure. 
These  are  usually  termed  the  four  original  convolutions, 
the  one  bordering  the  longitudinal  fissure  the  first,  that 
bordering  the  Sylvian  fissure  the  fourth  convolution.  In 
lower  mammalia,  as  the  rabbit,  there  are  only  indistinct 
sulci  on  the  surface  of  the  hemispheres,  and  no  convolu- 
tions distin{:tly  mapped  out.  In  the  monkey  and  man, 
on  the  other  hand,  this  four  convolution  type  appears  to 
have  been  wiped  out  through  the  appearance  of  new  feat- 
ures, especially  the  fissure  of  Rolando,  and  the  occipital 
fissures,  thereby  multiplying  the  number  of  convolutions. 


August  30,  1884.J 


THE  MEDICAL  RECORD. 


^35 


Nevertheless  a  careful  study  of  their  development,  and  of 
hains  of  different  races,  where  the  type  gradually  changes 
to  these  more  extreme  forms,  enables  us  to  trace  a  topo- 
graphiod  relationship  between  the  more  highly  developed 
convolutions  of  the  monkey  and  man,  and  the  four  con- 
Tolotion  type  of  other  mammalia.  It  thus  appears  that 
the  occipital  convolutions  are  the  posterior  extremities 
of  the  second  and  third  orif^inal  convolutions ;  and  the 
angular  gyrus  (a  part  we  will  have  occasion  to  refer  to 
again)  is  a  part  of  the  original  third  convolution.' 

I  may  mention  here  that  our  future  investigations  will 
lead  to  the  conclusion  that  the  cortical  visual  area  in  man 
is  mainly  in  the  occipital  lobes,  the  part  corresponding 
to  that  pointed  out  by  Munk  as  the  visual  area  in  the 
dogi  and  probably  also  to  that  in  the  rabbit  as  mapped 
out  by  Monakow. 

AGE  OF    GREATEST   RISK    FROM   CONSUMP- 
TION. 

By  henry  B.  baker,  M.D., 

LANSmC,  MICHIGAN. 

On  page  36  of  The  Rscord  for  July  12, 1884, 1  am  glad 
to  find  an  article,  illustrated  by  a  diagram,  showing  the 
death-rate  from  consumption  at  several  periods  of  age 
from  twenty  to  over  seventy  years.  Some  years  since  I 
prepared  and  published  in  a  volume  distributed  in  Michi* 
gan  ("The  Vital  Statistics  of  Michigan,  1870"^,  is- 
sued  in  1872,  a  similar  diagram  relating  to  the  oeaths 
returned  as  having  occurred  from  consumption  in  the 
State  of  Michigan  in  the  year  1870,  1,451  deaths  in  all, 
in  which  the  increased  proportion  of  deaths  to  inhabi- 
tants over  the  age  of  fifty-five  years  was  especially  notice- 
able. The  subject  is  one  .which  may  justly  claim  the 
attention  of  the  physician  as  well  as  the  student  of  vital 
statistics.  The  death-rate  of  females  was  much  greater  than 
Aat  of  the  males  at  ages  firom  ten  to  fifty-five  years,  ex- 
cept that  at  the  period  from  forty  to  forty-five  years  of  age 
the  death-rate  of  women  from  consumption  dropped  very 
noticeably ;  but  at  ages  fifty-five  to  seventy-five  years  the 
death-rate  of  males  was  greater  than  that  of  femsdes,  from 
this  disease.  The  number  of  deaths  of  those  above  the 
age  of  seventy-five  years  is  too  small  to  sive  a  steady 
mrve,  but  the  table,  and  especially  the  diagram,  shows 
well  the  death-rate  of  each  sex  from  birth  to  the  age  of 
seventy-five  years.  The  death-rate  from  consumption 
was  then  shown  to  be  least  at  the  ages  from  five  to  fifteen 
jears.  The  remarks  then  made  in  connection  with  the 
subject,  show  the  reason  for  the  fallacy  in  the  popular 
new  that  the  death-rate  is  greatest  at  ages  twenty  to 
twenty-five  or  twenty  to  forty;  the  number  of  deaths 
being  greatest  at  ages  twenty  to  twenty-five,  the  fact  of 
the  much  greater  proportion  of  inhabitants  at  those  ages 
than  at  the  older  ages  is  not  generally  held  in  mind. 


The  Rslation  between  Nervous  Afpections  and 
Diseases  of  the  Nose. — Dr.  Chiari  relates  three  cases 
of  nervous  affections  caused  by  swelling  of  the  mucous 
membrane  covering  the  inferior  turbinated  bones.  In 
two  of  these  cases  tihere  was  supraorbital  neuralgia,  which 
was  entirely  relieved  after  the  removal  of  a  number  of 
nasal  polypi.  The  third  patient  suffered  from  bronchial 
asthma.  Although  there  seemed  to  be  sufficient  cause 
for  the  trouble  in  an  aneurism  of  the  aorta,  nevertheless 
the  aadior  determined  to  reduce  a  slight  swelting  of  the 
mucous  membrane  covering  the  anterior  portion  of  the 
turbinated  bones.  This  was  done  by  means  of  the  gal- 
Tano-cautery,  and  the  result  was  a  perfect  eure  of  the 
asthma.  Dr.  Chiari  holds  that  one  ou^ht  to  search  the 
nostrils  for  a  possible  cause  of  asthma  in  every  instance, 
even  though  the  condition  of  the  heart  or  lungs  would 
seem  to  offer  a  sufficient  explanation  of  the  dyspnoea. — 
Deutsche  MedicifuU-Zeiiung^  June  9, 1884. 

>  WcrnickA :  Gehirnkraskheiten,  vol.  i« 


gr0j0tt^«BB  0f  pSCjedijcal  J^cieucje. 


Persistent  Omphalo- mesenteric  Remains^— The 
pouch-like  formation  of  intestine  occasionally  seen  pro- 
jecting from  the  lower  portion  of  the  ileum,  is  universally 
known  as  Meckel's  diverticuliun.  Not  that  this  distin- 
^ished  anatomist  was  its  discoverer,  but  to  him  we  owe 
not  only  the  almost  universal  acceptance  of  his  theory 
of  the  origin  of  the  pouch  in  question,  but  are  also  in- 
debted to  him  for  calling  conspicuous  attention  to  its 
importance  in  the  causation  of  serious  disease.  In  an 
article  in  the  July  number  of  The  American  Journal  of 
the  Medical  Sciences^  Dr.  Fitz,  of  Boston,  considers  this 
whole  subject .  and  points  out  that  the  view — that  most, 
if  not  all  well-authenticated  instances  of  duplication  of 
the  intestinal  tract,  at  any  part  of  its  course,  are  the 
probable  result  of  the  persistence  and  growth  of  the  re- 
mains of  the  vitelline  duct — is  rendered  highly  probable 
from  what  is  known  concerning  the  development  of  the 
intestine.  Attention  is  also  called  to  cystic  dilatation  of 
the  diverticulum.  These  retention  cySts,  as  they  are 
called,  may  have  their  cavity  continuous  or  discontinu- 
ous with  the  intestine.  Moreover,  such  cysts  of  possible 
intestinal  origin  are  not  limited  to  the  abdominal  cavity, 
having  been  observed  in  the  vicinity  of  the  oesophagus, 
in  the  abdominal  walls,  in  the  vicinity  of  the  umbilicus. 

Dr.  Fitz  points  out  that  the  vitelline  duct  is  com- 
posed not  only  of  layers  of  tissue  equivalent  to  those 
forming  the  coats  of  the  intestine,  but  it  is  also  accom- 
panied by  blood-vessels.  The  relation  of  these  omphalo- 
mesenteric vessels  or  their  remains  to  intestinal  strangu- 
lation is  fully  discussed,  and  the  importance  of  bearing 
in  mind  the  congenital  nature  of  certain  of  the  causes  of 
acute  intestinal  obstruction  is  earnestly  insisted  upon. 
Dr.  Fitz  finds  that — i.  Bands  and  cords  as  a  cause  of 
acute  intestinal  obstruction  are  second  in  importance  to 
intussusception  alone.  2.  Their  seat,  structure,  and  re- 
lation are  such  as  frequently  admit  their  origin  from  oblit- 
erated or  patent  omphalo-mesenteric  vessels,  either  alone 
or  in  connection  with  Meckel's  diverticulum,  and  oppose 
their  origin  from  peritonitis.  3.  Recorded  cases  of  intes- 
tinal strangulation  from  Meckel's  diverticulum,  in  most  in- 
stances, at  least,  belong  in  the  above  series.  4.  In  the 
region  where  these  congenital  causes  are  most  frequently 
met  with  an  occasional  cause  of  intestinal  strangulation, 
viz.,  the  vermiform  appendage,  is  also  found.  5.  It 
would  seem,  therefore,  that  in  the  operation  of  abdom- 
inal section  for  the  relief  of  acute  intestinal  obstruction 
not  due  to  intussusception,  and  in'  the  absence  of  local 
symptoms  calling  for  Uie  preferable  exploration  of  other 
parts  of  the  abdominal  cavity,  the  lower  right  quadrant 
should  be  selected  as  the  seat  of  the  incision. 

The  vicinity  of  the  navel  and  the  lower  three  feet  of 
the  ilium  should  then  receive  the  earliest  attention.  If 
a  band  is  discovered,  it  is  most  likely  to  be  a  persistent 
vitelline  duct — /.^.,  Meckel's  diverticulum,  or  an  om- 
phalo-mesenteric vessel  either  patent  or  obliterated,  or 
both  these  structures  in  continuity.  The  section  of  the 
band  may  thus  necessitate  opening  the  intestinal  canal 
or  a  blood-vessel  of  large  size.  £ach  of  these  alter- 
natives is  to  be  guarded  against,  and  the  removal  of  the 
entire  band  is  to  be  sought  for,  lest  subsequent  adher- 
ence prove  a  fresh  source  of  strangulation. 

On  Opening  and  Drainage  of  Abscess  Cavities  in 
THE  Brain. — Drs.  Fenger  and  I^ee,  in  a  paper  on  this 
subject  in  the  July  number  of  The  American  Journal  of 
the  Medical  Sciences^  consider  the  treatment  of  traumatic 
cerebral  abscess,  and  report  a  case  which  was  success- 
fully treated  by  opening  and  drainage. 

Bergman,  in  discussing  the  treatment  of  cerebral  ab- 
scess, unhesitatingly  sets  it  down  as  an  axiom  that  where- 
ever  there  is  an  accumulation  of  pus,  trephining  is 
most  clearly  and  indubitably  indicated,  for  the  opening 
of  an  abscess  in  the  brain  is  as  necessary  as  in   any 


^3* 


THE  MEDICAL  RECORD. 


[August  30,  1884. 


other  part  of  the  body,  and  we  would  add  even  more 
80*  A  correct  diagnosis  of  abscess  having  been  made, 
the  further  difficulty  presents  itself  of  locating  it  with 
sufficient  accuracy,  so  as  to  be  able  to  find  it.  A  num- 
ber of  cases  are  on  record,  in  which  a  correct  diagnosis 
had  been  made,  the  trephine  also  put  on  more  or  less  at 
the  right  place^  but  the  knife  or  trocar  being  passed  into 
the  brain,  nevertheless  missed  the  abscess.  Drs.  Fenger 
and  Lee  show  by  their  case  that  this  difficulty  can  be 
obviated  by  multiple  exploratory  aspirations,  performed  at 
interstices  sufficiently  small  to  prevent  any  abscess  from 
escaping  detection,  even  if  the  trephine  opening  should 
not  have  been  made  at  the  point  of  the  skull  nearest  the 
abscess, 

There  are  on  record  a  large  number  of  cases  of  cere- 
bral abscess  in  which  trephining  was  performed,  pus 
evacuated,  and  temporary  relief  obtained ;  but  later  re- 
lapse followed,  and  a  fatal  termination  ensued.  It  is 
possible,  judging  from  the  success  the  practice  has  met 
with  in  the  treatment  of  abscesses  in  other  situations,  that 
drainage  of  the  cerebral  abscess-cavity,  with  or  without 
washing  out,  would  have  saved  some  of  these  cases,  by 
preventing  the  reaccumulation  of  pus  aiid  the  continuous 
infection  of  the  surrounding  brain  tissue,  the  acute 
oedema  of  which  is  well  known  to  be,  as  a  rule,  the  final 
cause  of  death.  As  far  as  Drs.  Fenger  and  Lee  are 
aware,  draining  and  washing  out  of  cerebral  abscess- 
cavities  has  heretofore  not  been  tried;  that  it  can  be 
effected  and  without  any  detriment  to  the  patient,  is 
shown  by  their  case,  the  treatment  of  which  they  hold 
strictly  conforms  to  the  rational  methods  of  modern  sur- 
gery m  treating  abscesses  in  general;  and  because  of 
this,  and  not  because  their  patient  recovered,  they  re- 
gard the  case  as  answering  affirmatively  the  question : 
Is  it  probable  that  abscesses  in  the  brain  can  be  treated 
advantageously  on  the  same  principles  as  abscesses  in 
other  parts  of  the  body  ? 

Aspiration  of  the  Bladder. — Dr.  Hamaide  relates 
some  instances  of  impervious  stricture  of  the  urethra  in 
which  he  aspirated  the  bladder  from  thirteen  to  eighteen 
times  without  observing  any  unpleasant  symptoms.  He 
cites  these  cases  as  an  additional  evidence  of  the  safety 
of  this  procedure,  and  he  maintains  that  aspiration  is 
much  less  likely  to  do  harm  than  is  cadieterization  in  un- 
skilful Ym^d!^— Journal  deJii^cinedePariSt  No.  21, 1884. 

Traumatic  Cephalhydrocele. — ^The  occurrence  of 
subfascial  accumulation  pf  cerebro-spinal  fluid,  in  con- 
nection with  and  consequent  upon  simple  fracture  of  the 
vault,  is  of  great  rarity.  Two  cases  of  this  kind  are  re- 
corded by  Dr.  P.  S.  Conner,  of  Cincinnati,  in  the  July 
number  of  TTie  American  Journal  of  the  Medical  Sciences. 
So  far  as  he  has  been  able  to  ascertain,  there  have  been 
reported  but  nineteen  similar  cases,  and  three  others 
where  there  had  been  originally  a  communicating  wound 
of  the  scalp  which  had  closed.  As  £eu:  as  has  yet  been 
observed,  excluding  those  cases  which  were  primarily 
compound,  this  traumatic  cephalhydrocele  is  met  with 
only  in  young  subjects.  Explanation  of  this  fact  is 
probably  to  be  found,  at  least  in  part,  in  the  great 
elasticity  of  the  skull  in  infancy  and  early  childhood, 
permitting  of  marked  depression  and  Assuring  of  the 
vault  without  that  associated  wound  of  the  scalp  which 
would  be  likely  to  occur  were  ossification  complete ;  and 
in  part,  also,  in  the  much  closer  connection  of  the 
meninges  and  skull  in  children  than  in  youth  and  adults. 
The  decided  gravity  of  these  cases  is  apparent  firom 
the  statistics.  Of  the  eighteen  cases  of  simple  fracture 
in  which  the  result  is  known,  nine  (fifty  per  cent.)  died — 
eight  of  meningo-encephalitis  and  one  of  erysipelas  and 
meningitis ;  and  of  the  three  in  which  the  fracture  was 
originally  compound,  one  died  (thirty-three  and  one-third 
percent)  of  cerebral  abscess.  Even  die  supposed  recover- 
ies may  be  regarded  with  some  suspicion,  because  of  too 
early  report.  Dr.  Conner  draws  the  following  general  con- 
clusions :  I.  Simple  fracture  of  the  vault  of  the  skull  may 


give  rise  to  a  collection  under  the  scalp  of  the  cerebro- 
spinal fluid ;  coming,  it  may  be,  only  from  an  opened  ven- 
tricular  cavity.  2.  Such  traumatic  cephalhydrocele  may 
be  developed  quickly,  or  only  after  the  lapse  of  a  number 
of  days,  or  even  weeks.  3.  The  condition  is  one  that 
has  thus  fJBLr  been  noticed  only  in  young  subjects.  4, 
The  accident  is  quite  likely  to  jprove  fatal  fi-om  lepto- 
meningitis or  meningo-encephalitis.  5.  Operative  inter- 
ference should  be  restricted  to  the  removal  by  aspiration 
of  a  limited  amount  of  fluid  ;  and  such  aspiration  should 
be  made  only  when  severe  pressure  symptoms  have 
manifested  themselves.  6.  A  similar  fluid  accumulation 
may  occur  after  closure  of  the  external  wound  of  a  com- 
pound vault-fracture  or  of  a  trephining. 

Purification  of  Drinking-Water. — The  following 
method,  proposed  by  Professor  Almen,  of  Upsala,  is  rec- 
ommended by  Husemann :  To  a  quart  of  water  are 
added  a  drachm  of  a  5  per  cent,  solution  of  chloride  of 
iron,  and  from  i\  to  2  ounces  of  lime-water.  The  en- 
suing reddish-brown  precipitate  removes  all  the  floating 
particles  and  from  40  to  80  per  cent  of  the  soluble  or- 
ganic matters.  When  this  precipitate  has  settled  to  the 
bottom,  die  water  is  filtered  through  sand  or  fine  linen. 
— Deutsche  Medicinal-Zeitung^  June  5,  1884. 

The   Etiology  of  Convulsions   in  Childrkn.— . 
There  is  a  special  predisposition  in  children  to  convul- 
sions, and  this  is  due,  according  to  Professor  Kjellbeig, 
not  to  any  increased  irritability  in  the  motor  or  sensory 
tracts  or  m  the  reflex  centres,  but  to  the  fact  that  the 
brain  is  unable  to  exercise  any  controlling  influence 
upon  the  reflex  centres.     Convulsions  whidi  occur  at 
the  commencement  or  during  the  course  of  any  acute 
disease  through  direct  central  irritation  are  symptomatic 
Those  which  are  excited  reflexly  by  irritation  of  the 
sensory  nerve-endings  are  sympathetic      S)rmptODQatic 
convulsions  axe  due  m  part  to  disturbances  in  the  circu« 
lation  and  in  part'  to  changes  in  the  blood.     Among 
the  disturbances  in  the  circulatiany  the  most  common  is 
a  rapidly  produced  cerebral  anaemia.      This  may  be 
caused  by  hemorrhage,  a  rapid  waste  of  the  animal  fluids, 
or  arterial  spasm.     In  other  cases  it  is  due  to  cerebral 
compression  or  anatomical  changes  in  the  brain,  such  as 
extravasation  of  blood,  tumors,  softening,  etc     Hyper^ 
aemia  may  also  cause  convulsions  indirectly.     When  an 
excess  of  blood  is  carried  to  the  brain  the  cerebro-spinal 
fluid  in  the  perivascular  spaces  cannot  yield,  but  makes 
pressure  on  the  smaller  capillaries»  whereby  they  are 
emptied  of  their  blood,  and  the  real  condition  is  then 
anaemia  of  the  brain.     The  action  of  venous  stasis  is 
very  similar  in  depriving  the  brain  of  its  necessary  supply 
'of  arterial  blood.    There  are  often  changes  in  the  blood 
at  the  same  time  with  these  circulatory  disturbances. 
An  elevated  temperature  is  one  of  the  most  potent  of 
these  causes,  as  by  it  the  irritability  of  the  nerve-elements 
is  increased.     The  quality  of  the  blood  may  be  impaired 
also  by  the  introduction  of  poisons,  either  those  intro- 
duced from  without  or  those  formed  in  the  tissues  of  the 
body  itself    In  this  category  belongs  also  the  change  in 
the  milk  of  nursing  women  induced  by  violent  emotion. 
Sympathetic  convulsions  may  be  excited  by  almost  any 
irritation  of  the  sensory  nerve-endings,  in  consequence 
either  of  increased  irritability  of  the  nerves  or  of  dimin- 
ished power  of  the  reflex  controlling  centres.     In  regard 
to  the  presence  of  worms  in  the  intestinal  canal,  the 
author  admits  that  this  may  be  a  cause  of  convulsions, 
but  insists  upon  the  necessity  of  a  search  for  other  causes, 
since  worms  may  be  present  and  yet  have  nothing  to  do 
with  the  convulsions.     He  believes  also  that  dentition 
may  be  of  etiological  importance,  and  does  not  admit  as 
valid  the  objections   of  those  who  say  that  this  is  a 
physiological  process,  and  therefore  incapable  of  pro- 
ducing morbid  symptoms.     Although  he  does  not  doubt 
the  fact  of  an  hereditary  predisposition  to  convulsions  in 
certain  families,  he  admits  his  inability  to  explain  it — 
Schmidfs  JahrbOcher^  May  20,  1884. 


August  3o»  1884.] 


THE  MEDICAL  RECORD. 


^37 


Cortical  Lesions  of  the  Brain. — Dr.  M.  Allen 
Starr,  of  New  York,  in  the  July  number  of  like  Ameri- 
can Journal  of  the  Medical  Sciences^  has  collected  the 
American  cases  of  lesions  of  the  central  region  of  the 
brain,  and  carefully  studied  their  localized  symptoms. 
He  finds  that  disturbance  of  general  sensation — ^in- 
dading  the  sense  of  touch,  pressure,  pain,  and  tempera- 
ture, together  with  the  sense  of  the  location  of  a  limb — 
may  occur  either  in  the  form  of  subjective  perceptions 
of  such  sensations  without  objective  cause^  or  in  the 
form  of  impairment  of  these  sensations.  In  either  case 
it  indicates  a  disease  in  the  central  convolutions,  and 
possibly  in  the  adjacent  portion  of  the  parietal  lobules. 
The  power  of  voluntary  motion  of  the  muscles  of  the 
opposite  side  of  the  body  is  located  in  the  two  central 
convolutions  which  border  the  fissure  of  Rolando.  Mo- 
rions of  the  face  and  tongue  originate  in  the  lower  third 
of  this  r^on ;  motions  of  the  arm,  in  the  middle  third ; 
motions  of  the  leg,  in  the  upper  third.  Spasms  in,  or 
paralysis  of,  a  single  group  of  muscles  may  indicate  dis- 
ease of  its  motor  area.  Extensive  spasms  or  paralysis 
may  indicate  a  large  area  of  disease  in  this  region,  but  if 
more  marked  in  a  single  group  of  muscles  than  in  others 
it  may  indicate  a  small  focus  of  disease  in  the  motor  area 
of  that  group  affecting  other  motor  areas  indirectly  and 
coincidently.  Paralysis  following  spasm  in  one  group  of 
muscles  is  a  characteristic  symptom  of  disease  in  the  cen- 
tral region.  Disturbance  of  the  power  of  speech  indicates 
disease  in  the  convolutions  about  the  fissure  of  Sylvius  on 
the  left  side  in  right-handed  persons,  and  on  the  right  side 
in  left-handed  persons.  If  the  patient  can  understand  a 
question  and  can  recall  the  words  needed  for  a  reply, 
but  is  unable  to  initiate  the  necessary  motions  involved 
in  speaking,  the  disease  is  probably  in  the  third  frontal 
convolution  and  in  the  adjacent  portion  of  the  anterior 
central  convolution.  If  the  patient  cannot  recognize 
spoken  language,  but  can  repeat  words  after  another,  or 
can  use  exclamations  on  being  irritated,  the  disease  is 
probably  in  the  first  temporal  convolution.  If  the  pa- 
tient can  understand  and  can  talk,  but  replaces  a  word 
desired  by  one  that  is  unexpected,  the  disease  is  prob- 
ably situated  deep  within  the  Sylvian  fissure,  or  in  the 
white  substance  of  the  brain,  and  involves  the  association 
fibres  which  join  the  convolutions  just  named. 

.  Right's  Disease  of  Malarial  Origin. — Dr.  I.  R 
Atkinson,  believing  that  this  subject  has  not  attracted 
the  attention  it  deserves,  has  been  led  to  study  with 
reference  to  it  all  cases  of  malarial  fever  coming  under 
his  observation  during  the  late  summer  and  early  fall  of 
the  past  two  years  at  Bayview  Asylum,  and  the  result  he 
gives  in  a  paper  which  appears  in  the  July  number  of 
The  American  Journal  of  the  Medical  Sciences.  The 
conclusions  which  he  reaches  are  as  follows  :  i.  Transi- 
tory albuminuria  is  not  uncommon  in  the  course  of 
malarial  fevers,  and  is  due  to  the  intense  visceral  con- 
gestions characteristic  of  these  affections.  It  only  may 
endure  throughout  the  height  of  the  congestion,  recur- 
ring with  each  return  of  diis>  or  it  may  persist  in  the 
intervals,  in  which  event  a  higher  grade  of  congestion  is 
attained,  more  nearly  approaching  a  condition  of  acute 
inflammation.  2.  In  a  proportion  of  cases,  varying  with 
locality  and  type  of  prevailing  epidemic  or  individual 
conditions,  inflammation  of  the  kidney  occurs,  accom- 
panied by  dropsy  and  the  usual  symptoms  of  nephritis. 
3.  The  usual  form  of  malarial  nephritis  is  the  tubal  and 
diffuse  variety.  In  this  the  inflammation  seems  to  be 
most  intense  in  the  vicinity  of  the  glomeruli.  4.  Con- 
tracted kidney  may  occur  as  an  advanced  stage  of  ma- 
larial nephritis  either  firom  long-continued  or  frequently 
repeated  attacks  of  malarial  fever,  or  from  fibrotic  changes 
such  as  may  ultimately  occur  in  ordinary  tubal  or  diffuse 
nephritis.  It  is  altogether  improbable  that  this  form  of 
malarial  renal  disease  ever  occurs  primarily  as  purely 
interstitial  nephritis.  5.  These  changes  may  be  induced 
by  any  form  of  malarial  fever,  though  they  more  com- 


monly follow  chronic  intermittent  fever.  6.  The  ten- 
dency of  malarial  inflammation  of  the  kidney  is  toward 
recovery.  But  fit>m  the  persistence  of  the  impaludism 
or  the  intensity  of  the  inflammation,  structural  changes 
may  be  produced  that  are  characteristic  of  chronic 
Bright's  disease,  when  the  gravity  of  the  afiection  will 
be  as  that  from  chronic  Brighf  s  disease  from  whatever 
cause.  7,  Treatment  should  be  directed  primarily  against 
the  malarial  intoxication,  more  especially  in  recent  cases. 
A  correction  of  this  will  often  be  followed  by  a  complete, 
though  often  gradual,  subsidence  of  the  nephritis.  Even 
in  more  chronic  cases,  the  malarial  factor  in  the  process 
should  definitely  be  destroyed  if  possible,  after  which  the 
disease  should  be  treated  as  ordinary  Bright's  disease. 

Nerve-Stretching  in  the  Treatment  of  Epilepti- 
form Neuralgia. — Epileptiform  neuralgia,  or  so-called 
incurable  facial  tic,  is  a  disease  characterized  by  neuralgic 
paroxysms  of  great  intensity,  occurring  in  one  or  more 
branches  of  ti^e  fifth  nerve,  and  usually,  if  not  always, 
confined  to  one  side  of  the  face.  The  paroxysms  seldom 
last  more  than  half  a  minute,  and  recur  mth  great  irreg- 
ularity, sometimes  five  or  six  times  an  hour,  and  some- 
times not  more  than  twenty  or  thirty  times  in  the  twenty- 
four  hours.  They  may  be  determined  by  a  variety  of 
causes,  eating,  speaking,  washing  the  face,  or  any  periph- 
eral irritation  of  howsoever  trivial  a  nature.  The  treat- 
ment of  this  affection  has  hitherto  been  eminently  unsat- 
isfactory. Nearly  every  known  drug  has  been  tried 
without  efiect,  the  only  one  that  gave  even  a  measure  of 
relief  being  opium  in  large  and  repeated  doses.  Neu- 
rotomy, neurectomy,  the  introduction  of  hot  needles  into 
the  foramina  of  exit  of  the  different  branches  of  the 
nerve,  and  the  extirpation  of  one  of  the  ganglia  con- 
nected with  it  have  all  been  employed,  but  Imve  brought 
about  only  temporary  fi-eedom  from  the  paroxysms.  In 
an  article  on  this  subject  in  The  Practitioner  for  July, 
1884,  Mr.  W.  J.  Walsham  claims  to  have  cured  a  number 
of  cases  by  stretching  the  affected  nerve.  Three  of 
his  patients  had  previously  undergone  neurotomy  or  neu- 
rectomy with  but  temporary  relief,  while  nerve-stretching 
was  followed  by  the  most  happy  results.  The  author 
gives  a  brief  history  of  each  of  his  cases,  promising;  to 
publish  a  more  detailed  account  of  them  after  a  sufficient 
time  has  elapsed  to  satisfy  him  that  the  cure  is  a  perma- 
nent one.  Already,  at  the  time  of  writing,  the  patients 
had  been  relieved  of  their  pain  for  periods  of  firom  tinree 
mondis  to  three  years.  In  order  to  reach  the  inferior 
dental  nerve,  the  mouth  being  held  open  by  a  gag,  an 
incision  is  made  through  the  mucous  membrane  from  the 
last  molar  tooth  in  the  upper  jaw  to  the  last  molar  tooth 
in  the  lower.  The  finger  is  now  introduced  into  the 
wound  and  insinuated  between  the  ascending  ramus  of 
the  jaw  and  the  internal  pterygoid  muscle.  The  small 
spur-like  projection  of  bone  at  the  entrance  of  the  infe- 
rior dental  canal  is  next  felt  for  and  serves  as  a  guide  to 
the  nerve.  An  aneurism  needle  with  a  very  short  curve 
is  now  passed  and  hooked  around  the  nerve,  which  can 
be  then  drawn  visibly  into  the  entrance  of  the  wound 
The  structures  in  the  neighborhood  to  be  avoided  are  the 
inferior  dental  anery  and  gustatory  nerve.  It  should 
also  be  remembered  that  the  internal  lateral  ligament, 
which  is  inserted  into  the  spur-like  process  of  bone,  fol- 
lows somewhat  the  same  course  as  the  nerve,  and  might 
be  mistaken  for  it  In  order  to  avoid  this  it  is  necessary 
to  hitch  the  point  of  the  needle  in  the  entrance  of  the 
canal,  and  thence  sweep  it  upward,  backward,  and  out- 
ward around  the  nerve. 


Morphine  in  the  Vomiting  of  Pregnancy. — Dr. 
W.  C.  Roberts,  of  Albany,  Wisconsin,  writes  that  in  three 
cases  of  obstinate  vomiting  of  pregnancy  he  successfiilly 
used  muriate  of  morphine  per  rectum  in  half-grain  doses. 
Dr.  Roberts  asks  for  the  experience  of  others  with  mor- 
phine given  in  this  way. 


238 


THE  llCEDICAL  RECORD: 


[August  30,  1884. 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


PUBLISHSD  BY 

WM.  WOOD  &  Co.,  Nos.  56  and  58  Lafayette  Place. 
New  York,  August  30,  1884. 

SPERMATOPHOBIA  AND   SPERMATORRHOEA. 

If  we  may  except  the  able  treatise  of  Bartholow,  no  re- 
cent publication  has  handled  with  more  good  sense  and 
fairness  than  the  little  work  of  Malteot '  a  disease  which 
is  oftener  to  the  patient  a  terrifying  phantom  of  the  im- 
agination than  an  actuality,  but  which,  whether  fanciful 
or  real,  is  certain  continually  to  try  the  patience  and 
skill  of  the  busy  practitioner. 

Malteot  has  the  merit  of  showing  that  the  ''  classical 
tableau"  of  symptoms,  so  strikingly  set  forth  by  Lalle- 
mand  in  his  too  influential  work  published  in  1840,'  and 
since  then  adopted  and  improved  by  many  well-meaning 
writers  (to  say  nothing  of  the  harvest-field  which  this 
"  tableau "  has  been  for  quacks  in  all  lands),  is  found, 
when  subjected  to  a  rigorous  criticism,  to  have  little 
foundation  in  fact,  being  the  result  of  "  ignorance  of  the 
pathology  of  the  genito-urinary  organs,"  and  a  "  super- 
ficial^^agnosis,  devoid  of  scientific  precision."  Led 
astraj  by  a  preconceived  idea,  neglecting — what  is  as- 
suredly of  the  utmost  importance  in  diagnosis — ^the  help- 
ful guidance  of  the  microscope,  these  writers,  from  Lalle- 
mand  downward,  have  attributed  to  seminal  losses  (which 
either  did  not  exist  at  all,  or  were  ph3rsiological)  symp- 
toms which  ''  were  the  consequence  of  affections  of  the 
passages,  to-day  well  understood,  such  as  chronic  ureth- 
ritis, cystitis,  prostatitis,  or  urinary  tuberculosis."  Those, 
moreover,  who  are  familiar  with  Lallemand's  book 
know  that  he  dwells  much  on  certain  morbid  appearances 
of  the  urine — turbidity,  flocculence,  glaiiy  sediments,  etc. 
— as  indicative  of  the  presence  of  sperm  !  Even  Trous- 
seau, through  deference  to  Lallemand's  authority,  com- 
mitted the  same  error ;  he  placed  much  stress  on  the 
presence  in  the  urine  of  certain  <*  granulations,  and  bril- 
liant corpuscular  bodies,*'  on  which  Lallemand  also  in- 
sisted.* These  "  granulations  "  and  "  corpuscles  "  have 
been  invariably  found  by  Mal6cot  to  be  formed  of  '*  blad- 
der epithelium  and  pus  globules,  enveloped  in  a  reticu- 
lum of  fibrine ;  spermatozoids  were  absent." 

Certain  urethral  discharges  having  been  shown  to  be 
not  seminal,  and  of  little  prognostic  value,  how  shall  we 
account  for  the  accompanying  symptoms  which,  divested 
of  the  usual  exaggerations,  are  those  of  spinal  erethism 
—of  so-called  *' nervous  irritability"  or  "  debility,"  with 
consequent  depression  of  the  principal  visceral  functions  ? 


>  De  la  Spennatonii^    Doct  A.  Mal^cot.    Pp.  135.    Paris,  1884. 
'  Des  Pertes  Seminales  Invcdimtaires.     Montpdtier,  x839-4a 
*  IVoutseau :  De  la  Spermatorrhde.    Paris,  1867. 


One  of  three  suppositions  will  explain  all  of  these  cases, 
so  familiar  to  every  physician.  Either  the  neurotic 
symptoms  are  quasi-accidental  accompaniments  of  the 
bladder  or  urethral  troubles,  being  dependent  on  some 
common  cause  producing  functional  nervous  disturbance, 
as  overwork — mental  or  physical — alcoholism,  or  some 
other  vice  ;  or  they  are  the  expression  of  some  pathologi. 
cal  affection  of  the  brain  or  spine — ^an  extremely  frequent 
antecedent  of  the  ills  usually  attributed  to  seminal  losses; 
or  else  they  are  the  results  of  the  local  catarrhal  states, 
.  through  the  mysterious  but  well  attested  influence  of  the 
emotions  and  the  imagination  on  the  nervous  system  and 
the  organic  processes.  The  latter  division  will  embrace 
all  the  victims  of  what  Mal6cot  rather  infelicitously  calls 
**  physiological  spermatorrhoea ; " — ^young  men  who  make 
extravagant  account  of  their  occasional  seminal  losses, 
and  whose  habitual  emotional  firame  favors  an  erethistic 
condition  of  the  genital  organs,  and  of  whom  it  may  be 
affirmed  that  there  is  nothing  the  matter  with  them  but 
spermatophobia.  This  latter  word  is  so  good  and  so 
apposite  that  it  might  almost  be  used  to  indicate  a  defi- 
nite pathological  syndrome,  with  whose  outlines  every 
physician  is  acquainted.  Many  of  these  unhappy  per- 
sons are  veritable  hypochondriacs,  "always  preoccu- 
pied with  their  health,  attaching  an  excessive  importance 
to  the  least  urethral  discharge,  whatever  may  be  its  na- 
ture ;  **  fatiguing  by  their  prolixity  their  medical  attend- 
ant, who  vainly  endeavors  by  reason  or  by  banter  to  rid 
them  of  their  delusion. 

A  word  of  caution  is  here  necessary ;  these  patients 
are  often  real  sufferers.  If  the  occasional  losses,  ure- 
thral, prostatic  or  seminal,  are  of  little  or  no  detriment 
per  se^  the  state  of  mind  known  as  spermaiophobia  b  an 
actual  psycho-cerebral  disease,  akin  to  melancholia  or  the 
delirium  of  persecution.  In  fact,  one  of  the  cases  (Obs. 
xvi.)  reported  by  Malteot  as  "  imaginary  spermatorrhcea" 
concerns  a  patient  who  was  clearly  a  victim  of  mental 
alienation,  bordering  on  the  delirium  of  persecutim* 
Several  cases  of  insanity  cited  by  Lallemand  as  consecu- 
tive to  seminal  losses  are  also  instances  of  the  same  kind, 
the  insane  neurosis,  developed  to  activity,  not  by  sperma- 
torrhoea, but  by  spermatophobia.  Another  evil  is  likely 
to  result  from  the  intense  concentration  of  the  attention 
on  certain  organs  and  organic  states,  which  is  character- 
istic of  this  class  of  patients.  By  a  law  of  nervous  func- 
tion, not  yet  well  understood,  the  very  evil  which  is 
dreaded  may  be  engendered,  and  what  Mal^cot  caUs 
*'  physiological  spermatorrhoea "  may  end  in  the  patho- 
logical kind.  As  means  to  this  end  we  need  only  to  refer 
to  the  well-known  efiect,  on  certain  ill-balanced  minds,  of 
the  perusal  of  a  class  of  books,  unfortunately  too  preva- 
lent, and  sensational  advertisements  (fi-om  which  good 
newspapers  are  not  always  fi'ee),  published  in  the  interest 
of  quackery,  and  appealing  to  all  who  would  not  wish,  in 
the  flower  of  their  youthful  da3rs,  to  part  with  their  man- 
hood and  their  vitality. 

One  point  has  been  dearly  shown  in  the  treatise  of 
Mal^cot,  namely,  that  the  fiacts  of  the  disease  under  con- 
sideration have  been  understood  and  interpreted  differ- 
ently as  they  have  been  studied  by  physicians  or  by 
surgeons.  Surgeons  have  devoted  their  attention  too 
exclusively  to  the  genito-urinary  apparatus,  regarding  the 
disease  as  a  local  affection  and  demanding  local  treat- 


August  30^  1884.] 


THE  MEDICAL  RECORD. 


239 


mcDt;  pb3rsiciajis  have  emphasized  the  constitutional 
aspect,  seeing  in  spermatorrhoea  only  a  disease  of  the 
nervous  system.    The  latter  view  seems  to  be  the  cor- 
rect one.    It  is  now  very  generally  admitted  that  true 
spermatorrhoea  as  the  result  of  urethral  inflammations, 
of  an  over-sensitive  urethra  in  the  vicinity  of  the  vera 
mMianumy  of  "atony  of  the  ejaculatory  ducts,"  does  not 
exist    *•  To-day  the  hypothesis  of  a  sort  of  mysterious 
^imatorrhoea,  supervening  without  ejaculation,  by  par- 
alysis, by  want  of  contractility  of  the  ejaculatory  ducts, 
cannot  longer  be  maintained.    The  labors  of  Cadeat  and 
Robin  have  shown  that  while  the  vas  deferens  is  provided 
wi±  muscular  fibres,  the  ejaculatory  ducts  are  altogether 
destitute  of  any  muscular  coat,  being  constituted  of  elastic 
fibrous  tissue.     Despite  their  name,  then,  they  take  no 
acdve  part  in  the  phenomenon  of  ejaculation.   The  pres- 
ence of  sperm  in  the  urethra  seems  to  be  due  to  an 
OTeiflow  of  the  vesiculse  seminales,  too  great  fulness  of 
those  diverticula  overcoming  by  pressure  the  resistance 
of  the  ejaculatory  canals."  ' 

The  division  into  true  and  false  spermatorrhoea, 
adopted  by  Carlie  in  «  Quain's  Dictionary  of  Medicine,'* 
is  more  sensible  than  that  of  Malteot,  who  considers  the 
subject  under  three  heads  :  physiological^  imaginary^ 
i^ pathological;  the  two  first  divisions  corresponding 
to  Quain's  false  spermatorrhoea.  Under  the  head  of 
physiological^  however,  Mal^cot  includes  cases  which  are 
really  morbid,  1.^.,  the  pollutions  are  in  excess  and  at- 
tended with  debility,  owing  to  erethism  of  the  whole 
genito-spinal  nervous  apparatus ;  there  is  no  doubt  more- 
over that  this  genito-spinal  excitement  is  very  fi-equently 
the  result  of  abuses  of  the  sexual  fiinction.  Patients  of 
this  kind  are  always  benefited  by  marriage  and  moderate 
mdulgence.  True  spermatorrhoea  or  loss  of  seminal 
fluid  without  erection  or  without  sexual  desires  is  a 
malady  fortunately  as  rare  as  it  is  formidable.  It  is  not 
an  idiopathic  affection,  but  is  dependent  on  and  Sjrmp- 
tomatic  of  certain  morbid  states  of  the  cerebro-spinal 
axis.  Venereal  excesses  and  genital  afifections  are  only 
predisposing,  not  efficient  causes,  and  the  subjects  of  this 
disease  are  by  inheritance  neuropathic.  The  reflex 
shock,  of  which  the  pollution  is  the  final  expression,  may 
lead  to  more  or  less  exhaustion  of  the  nervous  centres, 
the  fright  and  anxiety  occasioned  by  the  nocturnal  losses 
may  have  a  powerfully  depressing  influence,  but  the  loss 
of  semen  is  of  no  consequence  whatever,  it  is  certainly 
not  the  cause  of  the  nervous  disturbance  and  the  pros- 
tration. 

There  are  certain  morbid  conditions  of  the  cerebrum, 
which  are  an  efficient  cause  of  spermatorrhoea.  Venereal 
excesses,  as  well  as  involuntary  pollutions,  are  often  the 
&st  symptoms  of  mental  alienation  and  of  general  par- 
alytic dementia,  perhaps  from  lesion  (as  Ferrier  sup- 
poses) of  a  special  sexual  centre  in  the  cortex.  There 
ait  certain  monstrous  aberrations  of  the  sexual  appe- 
tite  described  in  works  on  insanity  under  the  heads 
necrophily^  lycanthropyy  etc.;  onanism,  satyriasis,  and 
nymphomania  are  sometimes  noted  in  confirmed  hysteria 
and  epilepsy.  But  it  is  especially  in  irritative  affections 
of  the  spinal  marrow  that  we  observe  true  sperma- 
torrhoea ;  and  Trousseau  and  Charcot  have  both  pointed 

'  Joar.  de  PAnatomie  et  de  la  Phytiologie.  Pp.  xo6.  Paris,  1875.  Sur  quelqucs 
P«s  de  Mroctiire  des  canaux  ^acnlateim.    Alio  Mal^cot^  loc.  dt,  p.  41. 


out  the  frequency  of  this  disease  in  the  early  stages  of 
locomotor  ataxia.  Much,  however,  is  yet  needed  to 
complete  our  knowledge  on  this  subject. 


•'PASTEURIZATION"  AGAINST  HYDROPHOBIA. 

Recent  reports  fi-om  Paris  show  that  M.  Pasteur  has  un- 
doubtedly scored  another  success  in  his  scientific  work. 
The  Commission,  consisting  of  MM.  B^ard,  Paul  Bert, 
Buclez,  Tisserand,  Villemain,  Vulpian,  and  Bouley,  ap- 
pointed  to  investigate  M.  Pasteur's  claims  for  the  dis- 
covery of  a  protective  vaccine  against  rabies,  has  made 
its  report  The  members  have  gone  over  Pasteur's  ex- 
periments and  found  that  without  question  he  has  been 
able  to  protect  dogs  against  all  inoculations  with  hydro- 
phobic virus.  A  new  truth  is  bom  to  science,  therefore, 
viz. :  One  attack  of  hydrophobia  or  of  modified  hydro- 
phobia protects  against  another.  For  this  alone  Pasteur 
deserves  the  greatest  credit.  But  the  query  next  arises. 
Will  the  discovery  be  of  any  value?  This  depends 
mainly  upon  the  question  whether  inoculation  with  the 
vaccine  after  a  person  is  bitten  will  fiimish  an  efficient 
protection.  It  is  reported  that  Pasteur  has  tried  this 
already  in  one  case  and  with  success.  But  the  Commis- 
sion refirain  as  yet  firom  expressing  a  decided  opinion. 
They  will  "  continue  their  labors.*'  Meanwhile  M.  Pas- 
teur has  suggested  a  plan  of  protecting  the  human  race 
against  rabies  in  case  that  the  vaccine  fails  to  work  after 
a  person  is  bitten. 

This  plan  consists  in  nothing  else  than  the  compulsory 
"Pasteurization"  or  protective  inoculation  of  all  the 
dogs  in  the  country,  just  as  infants  are  compulsorily  vac- 
cinated. The  project  is  a  very  comprehensive  one,  but 
by  no  means  easy  to  carry  out,  in  view  of  the  large  UKm- 
ber  of  dogs  and  the  rapidity  with  which  they  multiply. 
Besides,  society  must  adjust  its  protective  labors  to  suf- 
ficient ends.  Hydrophobia  is  a  fearfiil  disease,  but  a  rare 
one. 

Perhaps  one  dog  in  a  million  gets  it  In  the  whole  o 
the  United  States  there  occurred  in  i860  only  38  deaths 
from  hydrophobia;  in  1870  only  63  cases.  In  New 
York  City  the  number  of  deaths  from  rabies  between  the 
years  1855  and  1874  was  57,  the  annual  number  ranging 
from  o  to  4.  In  England  the  annual  mortality  has  of 
late  years  ranged  from  20  to  50.  In  France  hydrophobia 
kills  about  200  persons  a  year. 

But  while  the  disease  is  a  small  element  in  mortality 
generally,  it  sometimes  appears  to  become  almost  epi- 
demic in  activity.  It  is  in  such  cases  and  under  such 
circumstances  that  "Pasteurization"  might  perhaps 
wisely  be  enforced. 


THE  PROPOSED  GROSS  MEMORIAL  PROFESSORSHIP. 

We  have  received  some  protests  against  the  views  ex- 
pressed regarding  the  proposed  memorial  professorship 
to  the  late  Professor  Gross.  We  should  be  very  sorry  to 
have  our  meaning  and  position  misunderstood,  as  evi- 
dentiy  has  been  done.  No  one  deserves  a  greater  or 
more  honorable  memorial  than  the  late  Professor  Gross, 
and  for  this  very  reason  we  protested  against  the  found- 
ing a  professorial  chair  in  a  private  medical  college,  as  a 
petty  and  inadequate  act  of  commemoration.     After  the 


240 


THE  MEDICAL  RECORD. 


[August  30,  1884^ 


chair  is  established,  only  medical  students  and  readers  of 
the  annual  catalogue  will  hear  of  it.  Professor  Gross' 
life  deserves  a  grander  and  more  conspicuous  monument 
We  regret,  therefore,  that  the  committee  having  the  mat- 
ter in  charge  did  not  make  a  wiser  choice.  Already 
signs  of  dissatisfaction  are  being  shown  among  the  physi- 
cians in  the  West  Let  the  committee  take  advice  that 
is  most  sincerely  meant  It  cannot  **  boom  "  a  project 
to  give  Jefferson  Medical  College  one  hundred  thousand 
dollars,  although  that  is  a  most  worthy  institution.  It 
can,  however,  by  a  very  slight  change,  make  its  proposed 
chair  of  pathology  a  public  lectureship  on  pathology  or 
some  allied  subject,  for  the  benefit  of  physicians.  Such 
lectureships  as  in  England  annually  commemorate  the 
names  of  Harvey,  Hunter,  Lettsom,  Gulston,  and  others, 
would  fittingly  adorn  the  memory  of  America's  greatest 
surgeon. 

THE  PARISIAN  AND  THE  BERLIN  VIEW  OF  THE 
COMMA-BACILLUS,  OR  SPIRILLUM. 
At  the  cholera  conference  in  Berlin,  of  which  we  give 
an  account  elsewhere.  Dr.  Koch  has  described  to  a  sym- 
pathetic audience  his  comma-bacillus,  and  given  his 
most  cogent  reasons  for  believing  it  to  be  the  true  cause 
of  the  cholera. 

Almost  at  the  same  time  M.  Strauss,  at  the  Acad6mie 
de  M6dicine  of  Paris,  gives  to  an  even  more  sympa- 
thetic audience  the  reasons  why  he  thinks  the  comma- 
bacillus  is  not  the  specific  organism  of  cholera.  He  states 
that,  in  connection  with  M.  Roux,  eighteen  autopsies 
were  made  upon  cholera  patients  at  Toulon.  In  the 
foudroyant  cases  the  comma-bacillus,  or  as  Koch  is  now 
inclined  to  call  it,  the  "  spirillum,"  was  found  abundantly  ; 
but  "  in  the  subacute  cases  it  was  impossible  to  detect 
their  presence."  Further,  Strauss  says  :  "  In  a  good 
number  of  cases  of  cholera  one  does  not  find  micro-or- 
ganisms in  the  intestinal  tunics." 

To  strengthen  his  argument  still  more,  M.  Strauss 
says  that  Dr.  Maddofe,  of  Tendres,  has  photographed  a 
comma-bacillus  which  he  has  found  in  a  reservoir  of 
water ;  that  M.  Malassez  has  shown  him  (Strauss)  bacilli 
of  comma  shape  obtained  from  dysenteric  stools.  M. 
Strauss  had  himself  seen  comma-bacilli  in  the  vaginal 
mucus  of  women  suffering  from  leucorrhoea,  and  in  the 
uterine  secretion  of  a  woman  suffering  firom  epithelioma 
of  the  neck. 

Although  M.  Strauss'  remarks  were  received  with 
much  favor  by  the  learned  Acad6mie,  his  argument 
appears  to  us  to  be  disingenuous  and  weak.  It  contrasts 
most  unfavorably  with  the  vigorous  exposition  of  his 
views  made  by  Dr.  Koch,  in  whom  we  are  more  than 
ever  inclined  to  feel  confidence. 


AMERICAN  JOURNALISTIC  ENTERPRISE. 

For  four  successive  issues  The  Medical  Record  has 
contained  reports  by  cable  of  the  proceedings  of  the 
two  most  notable  medical  gatherings  of  the  year.  We 
have  thus  been  able  to  present  the  main  features  of  these 
meetings  to  our  readers  even  sooner  than  they  were 
known  to  the  profession  in  Europe.  It  will  be  a  matter 
of  some  pride  to  bur  American  readers,  as  it  naturally  is 
to  ourselves,  that  in  journalistic  enterprise  The  Record 
has  so  far  outstripped  all  previous  efforts.  The  Record 
was  the  first  [medical  journal  to  use  the  Atlantic  cable, 


and  we  can  safely  say  that  its  cabled  reports  have  fax 
exceeded  in  number  and  length  those  attempted  any. 
where  else.  Our  readers  would,  we  are  sure,  excuse  this 
small  attempt  at  self-praise,  if  they  knew  the  amount  of 
extra  labor,  calculation,  and  expense  involved  in  these 
efforts  to  present  promptly  and  accurately  the  medical 
work  of  the  day. 

^exxTB  tit  ttije  "S^jeje^. 

The  American  Microscopical  Societt  held  its  an- 
nual meeting  last  week  at  Rochester,  N.  Y. 

The  American  Dermatological  Association.— The 
eighth  annual  session  of  the  American  Dermatological 
Association  took  place  this  week  at  West  Point,  N.  Y. 

Medical  Society  of  Northern  New  York.— The 
Fall  Meeting  of  the  Medical  Society  of  Northern  New 
York  will  be  held  at  the  City  Hall,  Albany,  Wednesday 
October  i,  1884. 

The  Cholera  has  continued  to  spread  through  the 
provinces  of  Southern  France  and  Northern  Italy,  and 
has  even  invaded  Switzerland.  Its  progress  has  been  of 
late  more  rapid  and  its  manner  of  attack  more  violent 
Thus  in  the  Western  Pyrenees  it  spread  to  thirteen  places 
within  a  week.  In  Italy  it  suddenly  attacked  La  Spezia 
on  August  2 2d.  In  three  days  there  had  been  79  deaths. 
The  correspondent  of  the  New  York  Times  telegraphs 
that  up  to  August  23d  there  had  been  3,952  deaths  from 
cholera  in  Southern  France.  These  deaths  were  dis- 
tributed among  one  hundred  and  thirty-one  cities  and 
villages,  in  fifteen  departments.  Up  to  August  15th  the 
disease  had  attacked  only  fifteen  places.  In  the  next 
week  it  had  spread  to  fifty-one  new  places.  In  Italy  the 
number  of  deaths  already  is  about  four  hundred,  and  this 
number  is  being  increased  daily.  The  number  of  prov- 
inces affected  is  six. 

Suicide  op  the  Late  Dr.  J.  J.  Woodward.— It  is 
known  that  the  late  Surgeon  Woodward,  U.S.A.,  was  in- 
sane at  the  time  of  his  death,  and  confined  in  a  private 
asylum.  There  seems  to  be  little  doubt  now  that  the 
unfortunate  man  met  his  death  by  his  own  hands.  An 
account  states  that  he  had  been  under  care  for  about  four 
months,  but  at  no  time  was  violent  or  in  any  way  trou- 
blesome. He  generally  preferred  to  be  let  alone,  and 
evinced  a  deHcacy  in  having  any  intrusion  upon  his 
privacy.  Though  of  a  strong  and  healthy  physique,  he 
imagined  himself  of  a  delicate  constitution.  He  was  as 
regular  as  clockwork  in  his  habits,  and  among  the  best 
patients  in  the  home.  On  Sunday  morning  he  was  passed 
on  the  stairway  by  one  of  the  lady  attendants,  who  saw 
him  on  the  edge  of  the  porch  roof.  A  few  minutes  later, 
before  anything  could  be  done  to  rescue  him,  he  threw 
himself  off  the  roof  backward,  falling  on  the  steps  below, 
receiving  injuries  from  which  he  died  on  the  afternoon 
of  the  same  day. 

Death  of  Dr.  Burq,  the  Metallo-Therapeutist. 
— The  death  is  announced  of  Dr.  Burq,  of  Paris,  aged 
sixty-two.  Dr.  Burq's  name  has  been  made  very  familiar 
to  the  medical  world  by  reason  of  his  persistent  efforts  to 
gain  a  scientific  standing  for  metallo-therapy.  This  he 
had  succeeded  in  doing,  at  least  in  France.  Of  late  he 
had  been  urging  the  prophylactic  value  of  copper  against 


August  3Py  1884.] 


THE  MEDICAL  RECORD. 


241 


cholenu  He  had  just  received  a  mass  of  testimonials 
from  miniDg  engineers,  bronze  and  copper  manufact* 
oiers,  doctors,  and  Sisters  of  Charity  in  favor  of  his 
copper  theory.  He  even  held  a  letter  from  a  doctor 
who  said  that  he  had,  after  gargling  his  throat  with  a 
solution  of  salts  of  copper,  sucked  with  impunity  diph- 
theritic matter  from  a  child  in  whose  windpipe  he  had 
made  an  incision.  Dr.  Burq  was  rejoicing  in  the  idea 
that,  owing  to  M.  Bert's  influence,  the  Municipal  Council 
in  future  would  cause  all  wood  employed  in  the  hospitals 
to  be  steeped  in  cupric  solution. 

Death  of  Dk  C,  W.  Chamberlain. — Dr.  Charles 
Walter  Chamberlain,  Secretary  of  the  State  Board  of 
Health  of  Connecticut,  and  a  member  of  the  National 
Board  of  Health,  died  in  Hartford  on  August  21st.  Dr. 
Chamberlain  was  bom  in  Providence,  R.  I.,  July  22, 
1844,  and  was  a  son  of  the  Rev.  Charles  Chamberlain. 
He  was  educated  at  Brown  University,  and  the  College 
of  Physicians  and  Surgeons  in  this  city,  graduating  from 
the  latter  institution  in  1871.  He  made  a  specialty  of 
laiyngology,  and  established  himself  in  Hartford.  He 
was  Secretary  of  the  State  Medical  Society  in  1876,  and 
contributed  to  the  Transactions  of  that  year  two  papers 
upon  throat  disease,  and  in  the  following  year  a  third 
paper  on  a  similkr  subject.  In  1877  Governor  Hubbard 
appointed  Dr.  Chamberlain  Examining  Surgeon  for  the 
soldiers  in  the  State  hospitals.  He  was  also  for  a  num- 
ber of  years  Examining  Surgeon  to  the  United  States 
Pension  Bureau,  and  was  well  known  throughout  the 
country  as  a  distinguished  sanitarian. 

The  Late  Dr«  Burq,  the  Copper  Specific,  and 
Pasteur. — ^The  Paris   correspondent    of  the  London 
Truth  writes:   ''And  now  a  little  benevolent  gossip 
about  the  arch-enemies  of  the  Cupric  Saviour.    Burq, 
*  fortified'  by  his  medicament,  has  been  since  1849,  <1^' 
ing  eveiy  cholera  visitation,  in  the  hospitals  of  the  towns 
where  it  was  most  virulent     He  faced  it  at  Toulon  and 
Marseilles,  in  Paris,  Rouen,  London,  and  Eastern  France. 
He  also  fietced  smallpox  in  its  worst  haunts.     Pasteur 
only  studies  these  maladies  at  a  distance.    A  little  virus 
is  brou^t  to  him  in  a  glass  tube,  and  then  he  operates 
with  it  upon  apes,  monkeys,  dogs,  and  guinea-pigs.     He 
preaches  ex  cathedrdj  and  all  the  cowards  who  are  afraid 
of  losing  their  worthless  lives,  and  who  cannot  bear  to 
think  that  firir  play  should  be  the  great  sweetener  of  the 
world  and  reign  everywhere,  laud  him  as  a  benefactor  of 
the  human  race  and  a  stamper*out  of  plague  and  pesti- 
lence.   When  a  contagious  disease  bums  itself  out  in  a 
l^ace  where  some  mitigated  virus  has  just  produced  as 
good  an  effect  as  Lourdes  water,  they  cry  out,  '  Great  is 
Pasteur  ! '    He  reminds  me  of  Vain-Hope,  the  ferryman 
in  the  ^  Pilgrim's  Progress,'  who  saved  people  the  trouble 
-^wading  through  the  river  which  lay  between  the  land 
I  Beulah  and  the  Celestial   Kingdom.     Poultry-yard 
lolera,  ovine  carbuncle,  murrain,  rinderpest,  smallpox, 
ariatina,  and  every  other  curse  upon  dirt  and  gluttony 
e  as  severe  as  ever,  and  yet  the  notion  is  abroad  that 
asteur,  through  his  scapegoat  animals,  has  taken  the 
ing  out  of  them  all.     Pasteur,  who  has  not  gone  to 
arseilles  to  correct  or  to  check  the  theories  he  builds 
}  in  his  torture-house  in  the  Rue  d'Ulm,  has  got  him- 
1f  appointed  French  Commissioner  to  the  Health  Con- 


gress which  is  to  be  held  at  Amsterdam.  I  don't  at  all 
try  to  convey  the  idea  that  he  is  a  humbug.  He  believes 
in  his  theories,  and  has  got  to  look  upon  himself  as  a 
divinity.  When  his  son-in-law  wrote  that  'Te  Pas- 
teurium  Laudamus '  (*  Monographe  de  Pasteur  par  un 
Ignorant ')  in  one  volume,  the  object  of  the  praises  him- 
self corrected  the  proofs  1  Pasteur  is  a  priest  who  lives 
by  the  altar.  He  has  25,ooof.  a  year  from  the  State  to 
enable  him  to  pursue  his  researches,  with  lodgings,  coal, 
and  lamplight,  and  is  soon  to  have  a  delicious  country 
residence  at  Villeneuve  I'Etang,  where  a  dogs'  Inferno  is 
being  created  for  him.  His  mitigated  viruses  are  a 
source — and  a  good  one — of  income.  He  has  married 
his  daughter  advantageously ;  through  Brown-Sdquard's 
and  Paul  Bert's  manias  for  vivisection  i  autrance  he  is  on 
good  terms  with  the  Opportunists,  and  owing  to  his  un- 
mitigated clericalism  he  enjoys  the  friendship  of  the 
dukes  and  counts  at  the  Academy.  If  a  king  starts  up, 
he  will  have  access  to  him  ;  if  the  republic  continues,  he 
will  go  on  drawing  his  25,ooof.  a  year.  His  son-in-law 
(the  author  of  the  'Te  Pasteurium  Laudamus ')  was,  a  few 
years  ago,  a  secretary  to  M.  de  Freycinet.  It  is  on  the 
cards  that  he  may  hereafter  receive  royal  dukes  at  Albert 
Gate  House." 

Dr.  Koch's  Berlin  Lecture  on  Cholera  and 
the  Comma-Bacillus. — ^An  important  conference  upon 
cholera  was  held  in  Berlin,  at  the  Imperial  Board  of 
Health,  on  the  evening  of  July  26th.  There  were  pres- 
ent Drs.  Von  Bergman,  Coler,  Eulenberg,  B.  Frankel, 
Gaffky,  Hirsch,  Koch,  Leyden,  S.  Neumann,  Pistor, 
Schubert,  Skreczka,  Struck,  Virchow,  and  WoUfhiigel. 
The  conference  had  been  called  at  the  instance  of  the  Ber- 
lin Medical  Society,  whose  President,  Professor  Virchow, 
explained  that  it  was  thought  advisable  Dr.  Koch  should 
in  the  first  instance  give  a  demonstration  of  his  work 
before  a  smaller  body  than  the  whole  Society,  so  that  the 
proceedings  might  be  fully  reported  in  the  medical  press. 
He  mentioned  that  Herr  Director  Lucanus  and  President 
Sydow  had  expressed  their  regret  at  being  unable  to  be 
present,  as  well  as  many  others,  including  Drs.  Von 
Lauer,  Von  Frerichs,  Mehlhausen,  and  Kersandt  Dr. 
Koch  first  showed  various  specimens  of  the  bacillus  and 
their  method  of  preparation  (see  Berliner  Klinische 
Wochenschrift^  August  4th).  This  resembles  that  for  the 
tubercle  bacillus,  viz.,  drying  on  a  cover-glass  and  stain- 
ing with  fiichsin  or  methyl-olin.  Koch  then  gave  a  his- 
tory of  his  work  while  in  Egypt  and  India.  His  post- 
mortem examinations  led  him  to  believe  that  the  intestines 
were  the  nidus  of  the  disease.  At  first  his  microscopical 
examinations  were  unsatisfactory,  but  finally  he  got  firesh 
dejecta  and  acute  cases,  and  then  discovered  the  comma- 
bacillus. 

This,  he  said,  is  smaller  than  the  tubercle  bacillus,  be- 
ing only  about  half  or  at  most  two-thirds  the  size  of  the 
latter,  but  much  more  plump,  thicker,  and  slighdy  curved. 
As  a  rule,  the  curve  is  no  more  than  that  of  a  comma  (,), 
but  soinetimes  it  assumes  a  semicircular  shape,  and  he 
has  seen  it  forming  a  double  curve  like  an  S ;  these  two 
variations  from  the  normal  being  suggestive  of  the  junc- 
tion of  two  individual  bacilli.  In  cultures  there  always 
appears  a  remarkably  free  development  of  comma-shaped 
bacilli.  These  bacilli  often  grow  out  to  form  long  threads, 
not  in  the  manner  of  anthrax  bacilli,  nor  with  a  simple 


242 


THE  MEDICAL  RECORD* 


[August  30,  1884. 


undulating  form,  but  assuming  the  shape  of  delicate  long 
spirals — a  corkscrew-shape — ^reminding  one  very  forcibly 
of  the  spirochsete  of  relapsing  fever.     Indeed,  it  would 
be  difficult  to  distinguish  the  two  if  placed  side  by  side. 
On  account  of  this  developmental  change,  he  doubted 
if  the  cholera  organism  should  be  ranked  with  bacilli ;  it 
is  rather  a  transitional  form  between  the  bacillus  and  the 
spirillum.     Possibly  it  is  true  spirillum,  portions  of  which 
appear  in  the  comma  shape,  much  as  in  other  spirilla — 
e,g.j  spirilla  undula,  which  do  not  always  form  complete 
spirals,  but  consist  only  of  more  or  less  curved  rods. 
The  comma-bacilli  thrive  well  in  meat  infusion,  growing 
in  it  with  great  rapidity.     By  examining  microscopically 
a  drop  of  this  broth  culture  the  bacilli  are  seen  in  active 
movement,  swarming  at  the  margins  of  the  drop,  inter- 
spersed with  the  spiral  threads,  which  are  also  apparently 
mobile.     They  grow  also  in  other  fluids — e.g,y  very  abun* 
dantly  in  milk,  without  coagulating  it  or  changing  its  ap* 
pearance.     Also  in  blood  serum  they  grow  very  richly. 
Another  good  nutrient  medium  is  gelatine,  wherein  the 
comma  bacilli  form  colonies  of  a  perfectly  characteristic 
kind,  dififerent  from  those  of  any  other  form  of  bacteria. 
The  colony  when  very  young  appears  as  a  pale  and  small 
spot,  not  completely  spherical  as  other  bacterial  colonies 
in  gelatine  are  wont  to  be,  but  with  a  more  or  less  irreg- 
ular, protruding,  or  jagged  contour.     It  also  very  soon 
takes  on  a  somewhat  granular  appearance.     As  the  col- 
ony increases   the  granular  character    becomes  more 
marked,  until  it  seems  to  be  made  up  of  highly  refhtctile 
granules,  like  a  mass  of  particles  of  glass.     In  its  further 
growth  the  gelatine  is  liquefied  in  the  vicinity  of  the 
colony,  which  at  the  same  time  sinks  down  deeper  into 
the  gelatine  mass,  and  makes  a  small,  thread-like  excava^ 
tion  in  the  gelatine,  in  the  centre  of  which  the  colony  ap- 
pears as  a  small  white  point.   This,  again,  is  peculiar ;  it  is 
never  seen,  at  least  so  marked,  with  any  other  bacterium. 
And  a  similar  appearance  is  produced  when  gelatine 
is  inoculated  with  a  pure  culture  of  this  bacillus,  the 
gelatine  liquefying  at  the  seat  of  inoculation,  and  the 
small  colony  continually  enlarging ;  but  above  it  there 
occurs  the  excavated  spot,  like  a  bubble  of  air  floating 
over  the  bacillary  colony.     It  gives  the  impression  that 
the  bacillus  growth  not  only  liquefies  the  gelatine,  but 
causes  a  rapid  evaporation  of  the  fluid  so  formed.    Many 
bacteria  also  have  the  power  of  so  liquefying  gelatine 
with  which  they  are  inoculated,  but  never  do  they  pro- 
djace  such  an  excavation  with  the  bladder-like  cavity  on 
the  surface.     Another  peculiarity  was  the  slowness  with 
which  the  gelatine  liquefied,  and  the  narrow  limits  of  this 
liquefaction  in  the  case  of  a  gelatine  disc     Cultures  of 
the  comma-badllus  were  also  made  in  Agar-Agar  jelly, 
which  is  not  liquefied  by  them.     On  potato  these  bacilli 
grow  like  those  of  glanders,  forming  a  grayish-brown  layer 
on  the  surface.    The  comma-bacilli  thrive  best  at  tern* 
peratures  between  30**  and  40°  C,  but  they  are  not  very 
sensitive  to  low  temperatures,  their  growth  not  being 
prevented  until  17**  or  16°  C.  is  reached.     In  this  respect 
they  agree  with  anthrax  bacilli.     Koch  made  an  experi- 
ment to  ascertain  whether  a  very  low  temperature  not 
merely  checked  development  but  killed  them,  and  sub- 
jected the  comma-bacilli  to  a  temperature  of   — 10®  C, 
They  were  then  completely  firozen,  but  yet  retained  vi» 
talitv.  oTOwin?  in  gelatine  afterward.     Other  experiments. 


by  excluding  air  ftom  the  gelatine  cultures,  or  pladna 
them  under  an  exhausted  bell-jar,  or  in  an  atmosphere  of 
carbonic  acid,  went  to  prove  that  they  required  air  and 
oxygen  for  their  growth ;  but  the  deprivation  did  not  kill 
them,  since  on  removing  them  from  these  conditions  they 
again  began  to  grow.  The  growth  of  these  bacilli  is  ex. 
ceptionably  rapid,  quickly  attaining  its  height,  and  after 
a  brief  stationary  period  as  quickly  terminating.  The 
dying  bacilli  lose  their  shape,  sometimes  appearing  shriv- 
elled, sometimes  swollen,  and  then  staining  very  slightly 
or  not  at  all.  The  special  features  of  their  vegetation 
are  best  seen  when  substances  which  also  contain  other 
forms  of  bacteria  are  taken — €.g.^  the  intestinal  contents 
or  choleraic  evacuations  mixed  with  moistened  earth  or 
linen  and  kept  damp. 

A  most  important  statement  was  that  the  comma- 
bacillus  seems  to  be  killed  by  the  bacteria  of  putrefaction, 
and  consequently  agents  that  destroy  the  latter  organisms 
without  the  former  may  really  do  injury,  by  removing 
from  the  cholera  bacillus  an  impediment  to  its  growth. 
As  for  destructive  agents  to  the  bacillus,  he  found  it  killed 
by  solutions  in  the  following  proportions  :  oil  of  pepper- 
mint, X  in  2,000;  sulphate  of  copper,  i  in  2,500  (a 
remedy  much  employed,  but  how  much  would  really  be 
needed  merely  to  hinder  the  growth  of  the  bacilli  m  the 
intestine!);  quinine,  i  in  5.000;  and  sublimate,  i  in 
100,000.  In  contrast  with  the  foregoing  measure  for 
preventing  the  growth  of  these  bacilli  is  the  striking  fact 
that  they  are  readily  killed  by  drying.  This  fact  is  proved 
by  merely  drying  a  small  drop  of  material  containing  the 
bacilli  on  a  cover-glass,  and  then  placing  this  over  some 
of  the  fluid  on  a  glass  slide.  With  anthrax  bacilli  vitality 
is  retained  for  nearly  a  week  ;  whereas,  the  comma-bacil- 
lus appears  to  be  killed  in  a  very  short  tinie. 

Dr.  Koch  having  found  and  cultivated  the  comma-ba- 
cillus, and  ascertained  its  distinctive  character,  next  pro- 
ceeded to  investigate  its  relation  to  cholera.  In  all 
there  were  now  about  one  hundred  cases  of  chol^a  in 
which  the  bacillus  had  been  found,  while  it  was  never 
found  in  connection  with  other  diseases.  Three  dif- 
ferent views,  said  the  speaker,  as  to  its  relation  to  the 
cholera  process  are  tenable,  i.  That  the  disease  favors 
the  growth  of  these  bacilli  by  afifording  them  a  suitable 
soil.  If  so,  it  would  mean  that  the  bacillus  in  question 
is  most  widely  diffused,  since  it  has  been  found  in  such 
dififerent  regions  as  Egypt,  India,  and  France ;  whereas 
the  contrary  is  the  case,  for  the  bacilli  do  not  occur  in 
other  diseases,  nor  in  the  healthy,  nor  apart  firom  human 
beings  in  localities  most  favorable  to  bacterial  life.  They 
only  appear  with  the  cholera.  2.  It  might  be  said  that 
cholera  produces  conditions  leading  to  a  change  in  form 
and  properties  of  the  numerous  intestinal  bacteria--a 
pure  hypothesis ;  the  only  instance  of  such  a  conversion 
refers  to  a  change  of  physiological  and  pathogenic  action, 
and  not  of  form.  Anthrax  bacilli  under  certain  condi- 
tions lose  their  pathogenic  power,  but  undergo  no  change 
in  shape ;  and  that  is  an  instance  of  a  loss  of  pathogenic 
properties,  while  there  is  no  analogy  to  support  the  view 
of  the  harmless  intestinal  bacteria  becoming  the  deadly 
cholera  bacilli.  The  more  bacterial  morphology  is 
studied,  the  more  certain  is  it  that  bacteria  are  constant 
in  their  form ;  moreover,  the  comma-bacillus  retains  its 
special  characters  unchanged  through  many  generations 


August  30,  1884.] 


THE  MEDICAL  RECORD. 


243 


of  culture.  3.  lastly,*  there  is  the  view  that  the  cholera 
process  and  the  comma  bacilli  are  intimately  related, 
and  there  is  no  other  conceivable  relation  but  that  the 
bacilli  precede  the  disease  and  excite  it  **  For  my  own 
pait,"  said  Dr.  Koch,  <<  the  matter  is  proved  that  the 
comma-bacilli  are  the  cause  of  cholera.'* 

Dr.  Koch  then  described  his  attempts  to  inoculate 
lower  animals  with  the  bacillus,  and  explained  the  cause 
of  his  Mure  in  the  natural  immunity  of  the  animals 
against  the  disestse. 

•  In  advocating  the  local  Indian  origin  of  the  disease  he 
laid :  That  the  virus  can  be  reproduced  and  multiplied 
outside  the  body  is  apparent,  since  the  bacillus  can  be 
Qoltivated  artificially,  and  its  growth  is  not  affected  by 
comparatively  low  temperatures.  Probably  it  does  not 
grow  in  streams  and  rivers,  where,  owing  to  the  current, 
a  sufficient  concentration  of  nutrient  substance  does  not 
occur;  but  in  stagnant  water  and  at  the  mouths  of  drains, 
etc.,  vegetable  and  animal  refuse  may  accumulate  and 
afford  the  necessary  nutriment.  Thus  is  explained  the 
propagation  of  cholera  by  the  subsoil  water,  and  the  in- 
crease of  epidemics  with  the  sinking  of  its  level,  which 
lessens  the  fiow  and  diminishes  the  amount  of  surface 
water.  Admitting  the  dependence  of  cholera  upon  this 
micro-organism,  it  is  impossible  to  conceive  the  disease 
having  an  autochthonous  origin  in  any  particular  place ; 
for  a  bacillus  must  obey  the  laws  of  vegetable  life,  and 
have  an  antecedent ;  and  since  the  comma  bacillus  does 
not  belong  to  the  widely  diffused  micro-organisms,  it 
must  have  a  limited  habitat.  Therefore,  the  occurrence 
of  cholera  on  the  delta  of  the  Nile  does  not  depend  on 
its  resemblance  to  the  delta  of  the  Ganges ;  but  the  dis- 
ease must  have  been  imported  there  as  it  is  into  Europe. 
It  was  once  thought  that  an  outbreak  in  Poland  had 
a  local  origin  until  it  was  discovered  to  have  been  intro- 
duced from  Russia.  Again,  about  ten  years  ago,  there 
was  a  sudden  outbreak  at  Hamar  (Syria),  thought  to  be 
an  instance  of  local  origin,  but  erroneously,  as  shown  by 
a  statement  of  Lortet,  who  told  Koch,  when  at  Lyons, 
that  the  epidemic  had  been  introduced  into  Hamar, 
where  he  was  at  the  time,  by  Turkish  soldiers  from 
Djeddah.  All  great  epidemics  of  cholera  began  in  South 
Bengal,  where  the  conditions  for  the  development  and 
growth  of  the  bacillus  are  most  perfect 

Dr.  Koch  concluded  with  a  reference  to  the  prospec- 
tive practical  value  of  his  discovery.  It  would  assist  in 
leading  to  intelligent  prophylaxis  and  treatment,  and  in 
making  an  early  diagnosis. 

At  the  close  of  his  lecture  a  discussion  took  place, 
which  we  shall  report  in  our  next  issue. 

Pleuro-pneumonia  in  the  West. — A  herd  of  Jersey 
cattle  infected  with  pleuro-pneumonia  were  sold  at  auc- 
tion recently,  and  the  disease  was  thus  disseminated 
through  several  herds  in  Illinois,  and  perhaps  other 
States.  The  condition  of  affairs  is  serious,  though  incom- 
parably less  so  than  if  the  disease  had  reached  the  great 
herds  of  beef  cattle  of  the  West  instead  of  smaller  herds 
of  registered  cattle. 

A  Philanthropic  Surgeon. — ^The  late  Sir  Erasmus 
Wilson  was  one  of  the  few  doctors  who  are  both  able 
and  willing  to  give.  Sir  Erasmus  distinguished  himself 
by  many  benefactions.     He   founded   a   chair  and  a 


museum  of  dermatology,  and  a  chair  of  pathology,  built 
a  master's  residence  at  Epsom  College,  and  part  of  a 
sea-bathing  hospital  at  Margate.  He  brought  Cleo- 
patra's Needle  to  England  at  an  expense  of  $50,000,  so 
that  the  obelisk  may  properly  be  considered  a  surgeon's 
needle,  and  he  gave  away  a  great  deal  of  money  in  pri- 
vate benefactions. 

Hog  Cholera  has  been  prevailing  since  last  winter  in 
certain  counties  of  New  Jersey. 

Druggists'  Conventions.  —  The  second  annual 
meeting  of  the  National  Druggists'  Association  was  held 
at  Milwaukee,  Wis.,  August  25th  and  26th.  This  is  the 
association  which  aims  to  promote  the  "  Campion  plan  " 
for  keeping  up  prices  and  cutting  off  the  "  scalpers." 
During  the  past  year  it  is  claimed  to  have  been  partially 
successful  The  Association  numbers  about  twenty-five 
hundred  members. 

On  August  26th,  the  National  Pharmaceutical  Asso- 
ciation convened  in  the  same  city. 


©Mtwarg. 


THE  LATE  SURGEON  J.  J.  WOODWARD,  U.S.A. 

War  Department, 

Surgeon.General*s  Office, 

Washington,  D.  C,  August  20,  1884. 

In  announcing  to  the  officers  of  the  Medical  Depart- 
ment the  death  of  Joseph  Janvier  Woodward,  Surgeon 
and  Brevet  Lieutenant-Colonel  U.  S.  A.,  which  oc- 
curred near  Philadelphia,  Pa.,  August  17,  1884,  the 
Surgeon-General  wishes  to  offer  his  tribute  of  respect  to 
the  memory  of  the  deceased,  whose  distinguished  career 
and  valuable  services  for  a  period  of  twenty-three  ^ears 
have  shed  lustre  on  the  corps,  and  for  whose  untmiely 
loss  feelings  of  profound  regret  will  be  shared  alike  by 
his  comrades  in  arms  and  b]^  the  profession  at  large. 

Dr.  Woodward  was  bom  in  Philadelphia,  Pa.,  October 
30,  1833,  and  was  educated  at  the  Central  High  School 
of  that  city,  graduating  with  honor  as  Bachelor  of  Arts  in 
1850,  and  receiving  the  degree  of  Master  of  Arts  from 
the  same  institution  in  1855. 

He  p;raduated  in  medicine  at  the  University  of  Penn- 
sylvaniai,  April,  1853  ;  entered  the  Army  as  Assistant 
Surgeon,  August  5,  1861 ;  became  Captain  and  Assist- 
ant Surgeon,  July  28,  1866 ;  Major  and  Surgeon,  June 
26,  1876.  "  For  faithful  and  meritorious  services  during 
the  War"  he  received  the  brevets  of  Captain,  Major, 
and  Lieutenant-Colonel  U.  S.  A. 

He  was  assigned  to  duty  in  this  Office  May  19,  1862, 
and  from  that  date  until  the  beginning  of  the  illness  which 
terminated  in  his  death  was  intimately  identified  with  its 
{MTofessional  and  scientific  work. 

While  the  valuable  results  of  his  life's  labor  are  com- 
prehended in  a  long  list  of  miscellaneous  publications, 
both  professional  and  scientific,  too  familiar  to  the  corps 
to  require  individual  mention,  his  jpreatest  triumphs  were 
won  in  the  field  of  microscopical  mvestigation  in  normal 
and  pathological  histology,  and  in  his  happy  application 
of  photo-micrography  to  the  purposes  of  science.  In 
these  pursuits  he  attained  remarkable  success,  and 
achieved  an  enviable,  world-wide  reputation,  leaving  to 
science  and  medicine  lessons  of  undoubted  value  and 
usefulness.  Of  his  strictly  professional  work  the  medical 
portion  of  the  '<  Medical  and  Surgical  History  of  the 
War  of  the  Rebellion  "  was  the  crowning  achievement. 
In  the  second  part  of  this  work  he  developed  the  results 
of  his  careful  investigations  into  the  nature  and  pathology 
of  the  intestinal  diseases  which  had  proved  so  fatal  in  the 


244 


THE  MEDICAL  RECORD; 


[August  30,  1884, 


late  war.  Here  also  he  displayed  his  wonderful  capacity 
for  that  minute  and  exhaustive  research  which  forms  so 
striking  a  feature  of  his  writings. 

As  in  the  case  of  his  co-laborer,  Otis,  he  yields  to  other 
hands  the  honor  of  completing  his  labors. 

In  addition  to  his  engrossmg  professional  duties,  his 
restless  activity  of  mind  led  him  to  seek  recreation  in  his 
favorite  studies — ^physics,  art,  and  philosophy. 

Endowed  with  a  retentive  memory  and  of  untiring  in- 
dustry, he  acquired  a  vast  store  of  information  whi(£  he 
held  available  for  use  at  will ;  fluent  of  speech,  he  took  de- 
light in  the  expression  of  his  views  and  opinions  both  in 
social  converse  and  in  the  arena  of  scientific  debate. 

His  fund  of  knowledge,  his  strong  convictions,  his 
tenacity  of  opinion,  and  his  quick  perception  made  him 
a  controversialist  of  no  low  order. 

With  such  a  record,  it  is  needless  to  speak  of  his  zeal, 
his  ambition,  or  his  devotion  to  his  profession,  and  espe- 
cially to  the  reputation  of  the  corps  of  which  he  was  so 
bright  an  ornament. 

Of  a  sensitive,  highly  strung,  nervous  organization,  the 
confinement,  anxiety,  and  labor  to  which  he  was  subjected 
in  his  attendance  upon  the  late  President  Garfield  during 
his  long  illness,  proved  too  much  for  a  mind  and  body 
already  overstrained  by  incessant  labor,  and  precipitated 
the  illness  which  finally  terminated  his  life. 

At  the  time  of  his  death  Dr.  Woodward  was  a  mem- 
ber and  ex-President  of  the  American  Medical  Associa- 
tion, a  member  and  ex-President  of  the  Washington 
Philosophical  Society,  a  member  of  the  National  Academy 
of  Science,  of  the  Association  for  the  Advancement  of 
Science,  of  the  Academy  of  Natural  Sciences  of  Phila- 
delphia, and  of  the  College  of  Physicians  and  Surgeons 
of  Philadelphia.  He  was  an  honorary  member  of  several 
American  and  foreign  scientific,  medical,  and  microscopi- 
cal societies,  and  the  recipient  of  many  distinguished 
honors  from  learned  bodies  in  this  country  and  abroad. 

R.  Murray, 
Surgeon-General  1/.S.A, 

Transactions  of  the  American  Gynecologal  Soci- 
ciETY,  Volume  VIII.  For  the  Year  1883.  New 
York :  D.  Appletou  &  Co.     1884. 

We  have  not  sufiicient  space  allowed  us  to  attempt  a 
critical  review  of  this  interesting  volume.  We  can  only 
furnish  to  the  general  reader  some  indications  of  its  con- 
tents. We  would  say,  in  the  first  place,  however,  that 
the  papers  and  discussions  are  quite  up  to  the  high  gen- 
eral average,  and  express  better  than  do  most  society 
transactions,  the  views  of  America's  leading  specialists 
in  gynecology.  On  the  whole  the  papers  have  a  more 
general  interest  than  is  the  case  with  much  other  special- 
istic  work« 

A  perusal  of  the  volume  before  us  shows  that  the  g3me- 
colo^sts  continue  to  entertain  a  healthy  difference  of 
opinion  upon  some  of  the  elementary  points  in  their  spe- 
cialty. For  example,  Dr.  £oimet  describes  a  new  oper- 
ation for  lacerated  perineum,  and  in  one  article  wipes 
out  all  his  previous  teachings  and  experience  on  this  sub- 
ject We  are  left  finally  in  doubt  whether  there  is  any 
perineum,  and  whether,  if  it  exists,  it  has  any  fiinction 
whatever.  The  well-worn  subject  of  dysmenorrhoea  is 
discussed  by  Dr.  C.  D.  Palmer,  and  by  Drs.  J.  R.  Chad- 
wick  and  Fordyce  Barker.  A  few,  more  or  less,  new 
specifics  for  this  trouble  are  given  ;  such  as  apiol,  cimici- 
fuga,  Pulsatilla,  coca,  and  ammonia.  Perhaps  it  may  be 
found  in  time  that  there  is  no  specific  for  any  form  of 
dysmenorrhoea,  but  that  a  great  many  drugs  relieve 
equally  well  the  same  distresses.  We  are  now  told  that 
such  a  thing  as  mechanical  dysmenorrhoea  rarely  exists. 
Dr.  R.  S.  Sutton  read  a  paper  on  *^  Cleanliness  in  Sur- 
gery'*  (subsequently  read  again   before   the  American 


Academy  of  Medicine),  in  which  he  introduced  the  sub- 
ject of  '*  Listerism."  Dr.  Lusk  made  an  interesting 
plea  for  the  spray,  but  gave  no  very  cogent  reasons  for 
Its  retention.  Dr.  A.  Reeves  Jackson  made  an  effective 
argument  against  the  operation  for  extirpation  of  the 
cancerous  uterus,  which  he  considered  useless  and  tti- 
justifiable.  Dr.  George  J.  En^elmann  denounced  the 
excessive  use  of  ergot  in  obstetric  practice,  and  thought 
that  this  drug  should  only  be  given  in  the  non-gravid 
uterus.  He  exaggerated  the  dangers  and  misuses  of 
ergot.  Dr.  Edward  W.  Jenks  described  a  new  mode  of 
operating  for  fistula  in  ano.  Dr.  Albert  H.  Smith  brought 
up  the  subject  of  **  Hot  Water  in  Secondary  Hemor- 
rhages after  Pelvic  Operations."  Hot  water  is  all  the 
vogue,  and  gynecology  (which  is  nothing  if  not  fashiona^ 
ble)  commends  it  in  the  present  volume.  Dr.  Gk>odell, 
to  be  sure,  finds  that  it  is  not  always  potent,  and  recom* 
mends  vinegar  as  an  addition. 

In  the  annual  address  of  the  President,  Dr.  Oilman 
Kimball,  attention  is  called  to  the  life  of  Dr.  Nathan  Smith, 
and  to  the  fact  that  he  independently  performed  ovari- 
otomy in  182 1,  knowing  nothing  of  McDowell's  oper- 
ation nine  years  before. 

As  regards  typographical  appearance  the  volume  con- 
tinues to  be  the  very  dude  of  medical  *'  transactions." 

Shaksspeare  as  a  Physician  :  Comprising  every  Word 
which  in  any  Way  relates  to  Medicine,  Surgery,  or  Ob- 
stetrics found  in  the  Complete  Works  of  that  Writer ; 
with  Criticisms  and  Comparison  of  the  Same  with  the 
Medical  Thoughts  of  To-day.  By  J.  Portbian  Chesney, 
M.D.  8vo,  pp.  226.  Chicago,  III.;  St.  Louis,  Mo.; 
Atlanta,  Ga. :  J.  H.  Chambers  &  Co.,  1884. 

The  title  of  the  above  work  very  clearly  indicates  its 
scope  and  purpose.  Beginning  with  obstetrics,  the  author 
gives  ui  quotations  from  every  play  containing  even  re- 
mote  and  incidental  allusions  to  that  subject  It  is  a 
medical  concordance  of  Shakespeare,  with  comments  and 
explanations.  The  author  says,  no  doubt  with  truth,  that 
his  task  has  not  been  a  slight  one.  Whether  the  result 
is  worth  the  trouble,  is  a  question  that  will  be  answered 
very  differently,  according  to  the  standpoint  of  the  reader. 
For  our  part  we  are  glad  to  find  that  doctors  occasionally 
have  the  taste  and  inclination  to  wander  a  little  in  the 
byways  and  produce  some  .work  outside  the  beaten  paths 
of  pathology.  Dr.  Chesney  has  done  his  work  con- 
scientiously, and  it  fiimishes  a  volume  of  curious  interest 
to  the  physician.  His  comments  are  perhaps  the  least 
interesting,  and  are  at  times  unnecessaxily  discursive  and 
pedantic ;  still,  not  much  other  than  explanation  and  a 
superficisd  exegesis  could  be  expected. 

The  work  is  illustrated  with  a  number  of  curious  and 
more  or  less  appropriate  cuts. 

A  Text-Book  of  the  Principles  of  PHvsfcs.     By 

Alfred  Daniell,  M.A.,  Lecturer  on  Physics  in  the 

School  of  Medicine,  Edinbur^^.   London :  Macmillan 

&  Co.     1884. 

This  book,  says  the  author,  was  primarily  designed  as  a 

contribution  to  medical  education,  and  as  such  he  hopes 

it  may  be  found  usefiiL     He  treats  of  physics  in  a  very 

different  manner  to  that  in  the  older  works  of  fifteen  or 

twenty  years  a^o.     His  book  is  written  strictly  fi'om  the 

modem  scientific  standpoint,  and  gives  the  latest  and 

best  conceptions  of  matter  and  the  physical  forces. 

Some  idea  of  the  systematic,  yet  natural  and  thorough 
manner  with  which  the  subject  is  treated,  may  be 
gathered  from  the  titles  of  the  chapters.  These  are  in 
their  order :  Time,  Space,  and  Mass ;  Measurements ; 
Work  and  £nergy ;  Kinematics ;  Kinetics ;  Attraction  and 
Potential;  Gravitation;  Matter;  Solids;  Liquids; 
Gases  ;  Heat ;  Sound,  etc 

It  would  be  a  ^eat  thin^  for  medical  students  if  the]r 
were  thoroughly  disciplined  in  a  work  like  this.  We  fear, 
however,  that  it  would  befog  the  untrained  brain  of  the 
majority  of  them. 


August  30,  1884.] 


THE  MEDICAL  RECORD. 


245 


^evovts  Off  S^ocUtizs. 


THE  BERLIN  SOCIETY  OF  INTERNAL  MED- 
ICINE. 

Stated  Meetings  July  14,  1884. 

Hkrr  Leyden,  President,  in  the  Chair. 

(Speciftl  Report  fer  Tkb  Msz»cal  RacoRD.) 

The  Society  having  been  called  to  order  by  the  President, 
HiRR  Kronecksr  exhibited  an 

APPARATUS   FOR  THE   INFUSION   OF   SALINE   SOLUTIONS 

into  the  general  circulation.  The  speaker  stated  briefly 
the  principles  of  this  method,  which,  though  by  no  means 
a  new  procedure,  was  still  not  so  widely  known  and 
appreciated  as,  by  reason  of  its  value,  it  ought  to  be. 
There  were  several  precautions  to  be  observed  in  em- 
ploying this  method  for  restoring  the  normal  fluidity  of 
the  bloody  the  first  and  most  important  of  which  was  to 
secure  a  suitable  solution.  He  had  formerly  thought  it 
important  to  add  a  certain  proportion  of  soda  to  the  solu- 
tion, but  had  recently  omitted  the  alkali  and  had  ob- 
tained equally  good  results.  Experiments  on  animals 
had  shown  that  a  solution  which  was  suitable  for  one 
species  might  be  harmful  to  another,  hence  it  was  not 
safe  to  conclude,  without  further  trial,  that  a  mixture 
which  was  well  borne  by  certain  animals  would  be  suit- 
able for  the  human  subject.  Some  recent  experiments 
by  Aronsohn  and  Marckwald  had  shown  that  a  propor- 
tion of  -^  part  of  chloride  of  sodium  to  100  parts  of 
distilled  water  (about  56  grains  to  the  pint)  caused  no 
irritation  to  the  mucous  membranes  or  subcutaneous 
tissues,  and  the  speaker  proposed  a  solution  of  this 
strength  as  the  one  best  adapted  for  intra- venous  injec- 
tion. 

Regarding  the  proper  method  of  introducing  the  solu- 
tion into  the  circulation,  Herr  Kronecker  expressed  a 
decided  preference  for  intra-venous  over  subcutaneous 
injection,  as  offering  the  greater  certainty  that  the  fluid 
will  be  taken  up  by  the  blood  stream.  But  great  care 
should  be  observed  not  to  inject  the  solution  too  rapidly 
or  with  two  great  pressure,  because  of  the  danger  of  fill- 
ing the  heart  with  water  and  driving  from  it  all  the  blood. 
Having  made  a  number  of  observations  on  this  point,  the 
speaker  had  been  able  to  set  five  drachms  per  second  as 
the  limit  beyond  which  we  should  not  pass  in  making  intra- 
venous injections  of  fluids  other  than  blood.  For  mak- 
ing the  injection  we  need  a  bottle,  graduated  to  drachms, 
to  which  a  rubber  tube  with  canula  attachment  is  fastened. 
By  holding  the  bottle  at  a  proper  height  we  are  enabled 
to  force  the  fluid  at  any  desired  rapidity  into  the  veins ; 
but  as  the  pressure  varies  according  to  the  amount  of 
fiuia  contained  in  the  flask,  the  height  at  which  the 
latter  is  held  must  be  constantly  raised  during  the  opera- 
tion. In  order  to  obviate  the  necessity  of  this,  Herr 
Kronecker  had  recently  employed  a  Mariotte  flask,  by 
means  of  which  a  constant  pressure  is  obtained,  whatever 
may  be  the  variation  in  the  quantity  of  the  contained 
fluid. 

One  great  advantage  possessed  by  the  saline  solution 
was  that  it  could  be  disinfected.  The  air  in  the  flask 
could  also  be  kept  perfectly  pure  by  allowing  it  to  pass 
through  cotton  saturated  with  a  disinfectant  solution. 

Herr  Leyden  thought  that  the  question  of  saline  in- 
fusions was  a  timely  one  in  view  of  the 

EPIDEMIC  OF  cholera) 

in  southern  Europe.  He  hoped  that  the  measures  which 
had  been  adopted  would  be  eflectual  in  keeping  the  dis- 
ease out  of  Germany.  But  it  was  only  the  part  of  ordi- 
nary prudence  to  make  every  preparation  to  grapple  with 
it  ^ould  it  once  gain  admittance.  He  thought  that  in 
Ae  event  of  being  called  upon   to  treat  cholera   the 


method  of  intra-venous  injections  just  demonstrated 
would  find  a  ready  application. 

Herr  S.  Guttmann  thought  it  would  be  advisable  to 
appoint  a  commbsion  to  determine  just  how  far  trans- 
fusion was  of  value  in  the  collapse  consequent  upon  the 
loss  of  fluids  in  cholera,  and  also  to  settle,  as  far  as  mi^ht 
be,  other  points  in  the  prophylajus  and  therapy  of  the  ms- 
ease.  Koch's  discovery  of  the  parasitic  nature  of  the 
affection  had  as  yet  led  to  no  practical  therapeutic 
results,  and  we  now  stood  in  the  presence  of  cholera  just 
as  defenceless  as  we  were  a  decade  ago. 

The^discussion  then  turned  upon  the 

prevention  and  treatment  of  cholera. 

Herr  Fraentzel  recalled  the  fisict  that  it  was  only 
during  the  last  epidemic  in  Berlin  that  attempts  were 
made  to  improve  the  hygienic  conditions  and  that  phy- 
sicians sought  to  formulate  any  dietary  rules.  Smce 
that  time  considerable  advances  had  been  made  in  these 
subjects.  Experiments  had  proven  the  futility  of  sub- 
cutaneous injections  of  saline  solutions,  for  the  tissties 
would  not  absorb  the  fluid,  and  the  only  result  of  an  in- 
jection was  the  formation  of  a  tumor,  which  disappeared 
only  after  the  lapse  of  considerable  time.  He  did  not 
deny,  however,  that  intra-venous  injections  might  prove 
more  useful. 

The  speaker  regretted  the  fact  that  less  attention  was 
now  paid  to  the  subject  of  disinfection  than  formerly. 
He  called  attention  also  to  the  danger  from  mill-streams 
which  contained  large  quantities  of  filth  and  decompos- 
ing matters,  and  he  hoped  that  some  measures  .would  be 
t^en  looking  to  their  purification. 

Herr  P.  Guttmann  had  made  a  trial  of  the  infusion 
of  saline  solutions  during  the  epidemic  of  1866,  but  all 
the  patients  so  treated  died.  He  did  not  believe  the 
cholera  would  reach  Berlin  this  year,  but  promised,  in 
case  it  did,  to  make  further  trials  with  the  method  just 
demonstrated.  He  insisted  upon  the  necessity  of  remov- 
ing all  cholera  patients  to  a  special  hospital,  since,  were 
they  treated  in  all  the  hospitals  throughout  the  city, 
there  would  be  created  so  many  additional  foci  of  disease. 

Herr  Loewenstein  did  not  anticipate  any  brilliapt 
results  in  the  treatment  of  cholera  by  saline  injecrions. 
Restorative  measures  were  needed,  and  unless  it  were 
shown  that  saline  infusions  exerted  an  analeptic  action 
upon  the  heart,  he  could  not  place  any  dependence  upon 
them. 

Herr  GuTTSTADT  spoke  of  the  danger  of  rectal  injec- 
tions in  cholera,  as  any  irritation  of  die  mucous  mem- 
branes was  liable  to  excite  a  diphtheritic  inflammation. 

Herr  Leyden  thought,  notwithstanding  the  general 
opposition  to  saline  injections,  that  possibly,  owing  to 
new  methods  of  preparation  and  perfected  apparatus, 
this  mode  of  treatment  might  eventually  be  found  useful 

A  cholera  commission  was  then  appointed,  consisting 
of  Herren  P.  Guttmann,  Baer,  Goltdammer,  S.  Gutt- 
mann, Lehnert,  Riess,  and  Wemich. 

Herr  P.  Guttmann  then  read  a  paper  upon 

ANTIPYRIN. 

A  number  of  remedies  had  recently  been  made  by  syn- 
thetic processes,  which,  in  suitable  doses,  possessed  a  febri- 
fuge action.  They  were  all  derivatives  ofi  or  closely 
allied  to,  chinolin.  One  of  these  substances  was  antipyrin, 
chemically  known  as  dinaethyloxychinicin.  It  is  freely 
soluble  in  water  and  alcohol,  possessing  a  slightly  bitter 
taste,  and  exists  in  the  form  of  a  powder  of  a  whitish 
color  faintly  tinged  with  yellow.  One  of  its  most  valu- 
able properties  is  its  great  solubility  (seven  grammes  of 
antipyrin  dissolving  in  three  grammes  of  water),  thus  ren- 
dering it  especially  adapted  for  hypodermic  use.  The 
author  had  employed  the  remedy  in  a  large  number  of 
cases  of  typhoid  fever,  pneumonia,  pulmonary  phthisis, 
measles,  scarlatina,  and  other  diseases  marked  by  a  high 
degree  of  fever.  He  had  found  in  every  instance  that 
the  exhibition  of  a  drachm  to  a  drachm  and  a  half  of  an- 


246 


THE   MEDICAL  RECORD. 


[August  30,  1884. 


tipyrin,  in  half*drachm  hourly  doses,  reduced  the  tem- 
perature curve  for  at  least  five  or  six  hours,  and  some- 
times for  a  still  longer  period.  The  drug  may  also  be 
given  in  a  single  large  dose  of  a  drachm,  or  in  fifteen- 
grain  doses  five  times  repeated,  with  similar  beneficial 
effects.  The  dose  for  children  is  seven  grains  firequently 
repeated. 

When  half-drachm  doses  are  given,  the  temperature 
begins  to  fall  even  during  the  first  hour,  but  reaches  its 
lowest  point  at  the  end  of  the  third  or  fourth  hour.  The 
minimum  reduction  observed  by  the  author  was  i®  F., 
and  the  maximum  7^.  The  temperature  begins  to  rise 
again  about  an  hour  after  the  last  dose  is  taken,  but  the 
ascending  curve  is  so  very  gradual  that  it  is  usually  ten 
or  twelve  hours  before  the  remedy  need  be  again  exhib- 
ited. There  are  no  unpleasant  symptoms  produced, 
with  the  occasional  exception  of  vomiting.  The  only 
pyretic  condition  over  which  antipyrin  exerts  no  effect 
is  intermittent  fever,  though  even  here  the  paroxysm 
seems  to  be  less  severe  if  a  full  dose  of  the  drug  has 
been  given  before  its  onset. 

The  febrifuge  action  of  antipyrin  is  only  one-half  as 
powerful  as  that  of  quinine,  that  is,  it  requires  one 
drachm  of  the  former  to  produce  the  effect  obtained  by 
thirty  grains  of  the  latter.  Unfortunately  at  present  an- 
tip3rrin  costs  two-thirds  as  much  as  quinine,  hence  it  can- 
not be  recommended  on  account  of  its  cheapness.  When 
it  becomes  possible  to  lower  the  cost  of  its  production, 
it  will  rank  as  a  febrifiige  much  preferable,  in  most  cases, 
to  quinine. 

Herr  Tillmanns  had  employed  antipyrin  in  a  num- 
ber of  cases  with  success  at  the  Charit6  clinic.  In  eight 
cases  of  intermittent  fever  he  had  cut  short  the  par- 
oxysms by  antipyrin,  but  immediately  upon  the  discon- 
tinuance of  the  remedy  the  temperature  rose  again.  He 
had  found  the  dni^  of  especial  value  in  the  pyrexia  of 
phthisis.  In  typhoid  fever  the  patients  expressed  them- 
selves as  feeling  much  better  after  taking  half-drachm 
doses  of  antipyrin,  and  the  drug  seemed  also  to  exert  a 
controlling  effect  upon  the  diarrhoea.  The  antipyretic 
action  of  the  drug  was  in  every  case  prompt  and  certain, 
and  was  accompanied,  especially  in  phthisis  and  pneu- 
monia, by  a  rather  profuse  perspiration.  No  injurious 
effects  were  ever  observed. 

In  conclusion,  the  speaker  stated  that  the  results  ob- 
tained by  him  were  in  accord  with  those  of  the  author  of 
the  paper.  He  would,  however,  advise  beginning  the 
administration  of  antipyrin  by  small  doses  (10-15  grains 
or  less),  which  could  then  be  increased  if  necessary. 
This  caution  should  specially  be  heeded  in  phthisis,  as  he 
had  seen  rather  alarming  symptoms  of  collapse  follow  the 
exhibition  of  large  doses. 

On  motion,  the  Society  then  adjourned. 


Irreducible  Hernia  Cured  by  Sneezing. — Dr.  John 
Burke,  of  this  city,  sends  us  the  history  of  a  man,  aged 
sixty,  who  had  suffered  for  several  years  fi-om  an  irreduci- 
ble left  inguinal  hernia.  Several  surgeons  had  tried  to 
get  it  back,  but  in  vain,  and  the  tumor  became  as  large 
as  a  child's  head.  One  night  he  was  attacked  with  a  fit 
of  coughing  and  sneezing,  which  continued  about  half  an 
hoiur,  according  to  his  own  and  wife's  report,  when  he 
felt  something;  give  way  within  him.  He  heard  a  gurgling 
and  the  hernia  had  disappeared.  In  the  morning  he  sent 
for  Dr.  Burke  who  found  that  the  mass  had  gone.  The 
ring  was  as  large  as  a  silver  dollar.  There  was  great  pain 
and  tenderness  about  the  parts  and  he  had  local  peri- 
tonitis. After  a  few  days  he  recovered.  He  since  has 
been  fitted  with  a  truss  and  the  hernia  has  not  come 
down.  Dr.  Burke  concludes  :  *'  Would  it  not  be  well  in 
some  of  these  cases  to  give  the  patient  a  good  pinch  of 
hellebore  to  bring  on  sneezing?  Perhaps  it  may  tear  away 
the  adhesions  and  cause  the  gut  to  return.  I  would  ask 
your  readers  if  they  ever  met  a  case  of  hernia  reduced  in 
that  manner." 


THE  BIOLOGICAL  SOCIETY  OF  PARIS. 
Stated  Meeting,  July  19,  1884. 
M.  Paul  Bert,  President,  in  the  Chair. 

(Spedal  Report  to  Thb  Mbdical  Rjbcord.) 

The  scientific  work  of  the  meeting  was  begun  by  M.  Ra- 
buteau,  who  made  a  few  remarks  upon  the 

TANNATES   IN   THE   TREATMENT  OF  CHOLERA. 

He  prophesied  that  the  workmen  in  the  tanneries  near 
Bi^vre  would  escape  cholera  in  case  of  an  epidemic  oc> 
ciuring  there.  In  the  case  of  a  patient  attacked  by  diar- 
rhoea m  the  first  stage  of  cholera,  he  would  begin  by 
administering  a  laxative  of  castor-oil  or  the  sulpho-car- 
bolate  of  soda,  and  would  follow  this  up  by  the  wine  or 
tincture  of  catechu  or  some  other  of  the  anti-cathartics 
containing  tannin.  He  would  permit  the  use  of  apricots, 
strawberries,  or  any  fruits  containing  tannin,  but  would 
forbid  melons. 

M.  Beauregard  had  been  studying  the 

HABITS   OP  THE   SPANISH   FLY, 

and  related  some  of  the  facts  which  he  had  discovered  in 
his  investigations.  The  leaves  of  the  lilac  are  the  favor- 
ite  food  of  these  insects.  The  flies  lay  their  eggs  in  the 
ground,  digging  a  burrow  some  distance  below  the  sur- 
face, and  there  depositing  two  little  spheres  each  contain- 
ing from  sixty  to  eighty  eggs.  The  grubs  are  hatched  at  the 
end  of  two  weeks.  Both  the  grubs  and  the  flies  subsist 
entirely  on  the  saccharine  juices  of  plants,  and  never  eat 
the  eggs  of  other  insects.  Cantharidine  is  present  at 
every  stage  of  development  of  the  insect.  Vesication 
may  be  obtained  by  using  the  eggs  or  the  larvae  as  well 
as  by  using  the  fully  developed  fly. 

M.  RifiMY  related  some  results  which  he  had  found  to      , 
follow  upon 

EXCITATION   OF  THE   SPERMATIC  PLEXUS. 

In  the  course  of  certain  experiments  upon  the  great  sym- 
pathetic nerve  in  the  Guinea-pig,  he  had  found  that  irri- 
tation of  a  small  ganglion,  lying  just  anterior  to  the  kidney,  ! 
caused  a  seminal  ejaculation,  and  when  continued,  excited 
an  erection.  The  action  was  centrifugal,  for,  if  the  nerve 
were  divided,  central  irritation  produced  no  result. 

M.  Quinquand  gave  the  results  obtained  by  him  in 
certain  experiments  made  to  determine 

THE  PATHOGENESIS   OF' UR/EMIA.  ^ 

The  opinion  of  pathologists  generally  of  the  present  day 
is  that  the  ursemic  symptoms  are  not  caused  by  the  ac- 
cumulation of  urea  in  the  blood,  but  the  speaker  clain^ed 
that  the  experiments  conducted  by  M.  Grdhant  and  him- 
self proved  that  this  opinion  was  incorrect  In  the  frog, 
the  subcutaneous  injection  of  fifteen  grains  of  urea  was 
followed  by  convulsions,  tetanus,  and  death  from  arrest 
of  the  respiratory  movements.  The  heart  continued  to 
beat  several  minutes  after  the  cessation  of  respiration. 
In  the  Guinea-pig,  epileptiform  convulsions  and  opisthot- 
onus were  produced.  In  the  dog,  the  s^ptomswere 
those  of  coma,  and  were  followed  by  death  in  from  fifteen  3 
to  thirty  minutes.  The  dose  of  urea  necessary  to  pro-  3 
duce  these  results  is  rather  large ;  in  the  Guinea-pig,  75 
to  90  grains  are  required ;  in  the  rabbit,  1 20  to  1 50  grains ;  j 
in  a  dog  weighing  6^  to  9  pounds,  150  to  180  grains. 
The  proportion  of  urea  in  the  blood  is,  however,  not 
large,  only  from  three  to  six  parts  by  weight  per  thousand. 

M.  RiCHET  said  that  he  had  often  injected  many  times 
larger  amounts  of  urea  in  the  dog  without  obtaining  any 
results.     He  used  the  substance  in  very  dilute  solution. 

M.  Quinquand  said  that  with  dilute  solutions  there 
were  never  any  uraemic  symptoms,  an  increased  secretion 
of  urine  was  the  only  result  produced. 

M.  Frank  asked  whether  the  so-called  uraemic  symp- 
toms observed  by  M.  Quinquand  might  not  have  been 
caused  by  the  irritation  of  the  skin,  resulting  from  the 


August  30,  1884-J 


THE  MEDICAL  RECORD. 


247 


injection  of  these  concentrated  solutions,  for  M.  Brown- 

S^uaxd  had  seen  like  symptoms  produced  by  irritant 

JDJections. 

^  M.  F^Ri  presented  a  communication  upon 

PARTIAL   SOMNAMBULISM. 

An  hypnotized  subject  who  is  cataleptic  or  lethargic  may, 
bymeans  of  friction  made  over  the  vertex,  be  thrown  into 
a  third  somnambulistic  state.  If  the  friction  be  made 
over  one  side  only  the  condition  is  one  of  hemi-somnam- 
bulism.  iff  instead  of  general  friction  over  the  vertex, 
strong  pressure  be  made  over  certain  portions  of  the 
scalp,  partial  sonmambulism  of  that  region,  whose  motor 
centre  in  the  cortex  corresponds  to  the  point  pressed 
upon,  results.  Thus  one-half  of  the  face,  one  arm,  or  one 
leg  may  be  affected.  It  is  even  possible  to  cause  partial 
somnambulism  of  the  upper  portion  onl^  of  the  face  by 
pressing  upon  that  part  of  the  skull  lying  above  a  hori- 
zontal line  prolonged  from  the  level  of  the  eyebrows,  and 
behind  a  vertical  line  drawn  posterior  to  the  mastoid  pro- 
cess. This  was  the  situation  of  the  cranial  lesion  in  a 
case  of  traumatic  tic  of  the  eyelids  observed  once  by  M. 

M.  GiBiER  then  related  some  experiments  upon  the 

INOCULATION   OF   RABIES 

in  birds.  He  found  that  the  intensity  of  the  virus  in- 
creased in  direct  ratio  with  the  number  of  inoculations 
practised.  The  period  of  incubation,  when  the  virus 
was  injected  into  the  anterior  chamber  of  the  eye,  was 
twelve  days. 
The  Society  then  adjourned 


(^owzsvan&enc6. 


INTERNATIONAL  MEDICAL  CONGRESS. 

(From  our  Special^Correspondent) 

(COPBNHAGICK,  DENMARK,  AugUSt  x6,  X884. 

THE  SUCCESS  OF  THE  CONGRESS — THE  NOTABLES  PRES- 
ENT— ^THE  SPEECHES  OF  JACOBI  AND  NOYES — ^AMERI- 
CAN ELOQUENCE  —  DR.  SAVRE  AND  HIS  PLASTER 
JACKET — HOW  CRUDELI  TREATED  MALARIA — ^VIRCHOW 
AND  HIS  SUBJECT — ^PASTEUR  AND  HIS  IMPRESSED  AU- 
DIENCE  ^THE    COLLECTIVE   INVESTIGATION   COMMITTEE 

—SOCIAL   ENJOYMENTS — WORK  AND   PLAY. 

You  have  doubtless  received  by  this  time  my  full  cable 
despatches  of  the  meeting  of  the  International  Medical 
Coogress  here,  and  have  formed  an  estimate  of  what  has 
been  done^ — not  only  what  has  been  done  in  a  strictly 
scientific  but  a  social  way.  The  meeting  was  [a  great 
success  in  every  particular.  The  weather  was  charm- 
ingly pleasant,  and  all  the  other  accesssories  were  at  hand 
to  enable  the  Committee  of  Arrangements  to  follow  out 
their  plan  within  as  well  as  without  doors  to  the  satisfac- 
tion of  every  one. 

Among  the  prominent  medical  men  from  New  York 
who  were  present  and  took  a  more  or  less  active  part  in 
Ac  proceedings  were  Drs.  A.  Jacobi,  H.  D.  Noyes, 
Joseph  W.  Howe,  and  Lewis  A.  Sa}Te.  Dr.  Jacobi 
made  an  impressive  and  telling  address  on  the  eve  of  the 
adjournment,  and  well  represented  the  cosmopolitan 
spirit  of  the  medical  profession  of  America.  Dr.  Noyes 
also  made  a  thrilling  speech  at  the  dinner  of  the  Ophthal- 
mological  Section  on  Monday,  in  response  to  the  health 
of  the  American  visitors.  He  was  merely  a  delegate  of 
a  large  working  community  on  "  the  other  side  "  who  had 
a  deep  sense  of  love  and  reverence  for  the  old  countries, 
and  especially  for  Denmark,  and  he  made  his  audience 
feel  it 

Dr.  Sayre  gave  some  exhibitions  of  his  plasterof-Paris 
jacket,  which  being  novel  to  most  of  his  hearers  attracted 
a  good  deal  of  attention.  If  any  one  who  has  attended 
the  recent  meetings  of  the  British  Medical  Association  I 


for  the  past  few  years,  or  other  medical  gatherings  in 
Great  Britain  and  elsewhere,  is  not  now  acquainted  with 
the  Sayre  jacket,  the  reasons  why  it  should  be  used  in 
all  cases,  and  the  way  it  should  be  used,  he  deserves  to 
be  pitied  as  an  ignoramus,  or  at  least  an  inattentive 
listener.  Certainly  the  distinguished  surgeon  and  his 
son  have  spared  no  pains  to  such  an  end,  either  as  to 
time,  place,  circumstance,  'or  surroundings.  But,  as  be- 
fore remarked,  his  demonstrations  were  well  received. 
The  most  mteresting  subject  presented  in  the  addresses 
was  that  on  malaria  by  Professor  Crudeli,  of  Rome. 
This  has  doubtless  been  published  with  the  cable  de- 
spatches. The  subject  was  one  that  interested  practition- 
ers generally,  although  some  of  the  views  enunciated  by 
the  distinguished  hygienist  were  somewhat  striking,  if  not 
heretical  in  their  tendency.  The  courteous  attention  of 
the  large  audience  throughout  the  delivery  of  the  address 
attested  its  merit  and  its  widespread  applicability  to  the 
wants  of  his  hearers. 

Virchow  drew  a  crowd  of  hearers,  more  on  account  of 
himself  than  his  subject.  He  did  his  best  to  infuse  in- 
terest into  his  theme,  and  this,  considering  his  impressive 
delivery  and  forcible  eloquence,  is  saying  a  great  deal. 
But  he  was  compelled  for  the  most  part  to  confine  him- 
self  to  abstruse  reasoning  on  mere  theories,  and  was  at 
times  tiresome  and  heavy. 

Pasteur  came  before  his  hearers  with  the  S^iaf  of  a 
star  actor  in  a  celebrated  part  Both  he  and  his  subject 
were  interesting,  but  the  former  even  more  than  the  lat- 
ter. The  audience  hall  was  crowded  to  its  uttermost, 
and  there  was  infused  in  his  delivery,  in  his  presentation 
c^  striking  fieicts,  and  in  the  apparently  modest  summing 
up  of  results,  a  sentimentality  which  told  strongly  on  his 
hearers.  But  Pasteur  is  a  great  man,  an  original  thinker, 
a  hard  worker,  and  one  who  knows  how  to  make  his  work 
appreciated.  The  principal  points  in  his  address  were 
cabled  as  fully  as  possible  in  the  rush  to  get  everything 
in  the  shortest  time,  but  perhaps  a  little  more  of  details 
as  to  experiments  performed  and  their  results  may  be  ac- 
ceptable just  here. 

When  he  had  discovered  his  method  of  vaccinating  dogs 
with  hydrophobic  virus,  and  so  made  many  dogs  insus- 
ceptible to  hydrophobia,  he  requested  from  the  govern- 
ment a  competent  committee  to  judge  of  his  results. 
The  request  was  granted  by  the  Minister  of  Education 
(M.  Falli^res),  who  appointed  B6clard,  Paul  Bert, 
BouUy,  Tisserand,  Villemain,  and  Vulpian,  members  of 
the  committee.  He  sUted  that  the  committee  had  just 
sent  its  report  to  the  Minister.  The  following  were  ito 
most  important  points : 

Pasteur  gave  23  vaccinated  dogs  to  the  committee. 
These  were  compared  with  19  non-vaccinated  dogs 
selected  by  the  committee. 

On  June  ist  2  vaccinated  and  2  non- vaccinated  dogs 
were  inoculated  by  trepanation  from  a  rabid  dog. 

On  June  3d  i  vaccinated  and  i  non-vacdnated  dog 
were  bitten  by  a  rabid  dog. 

On  June  4th  i  vaccinated  and  i  non-vacdnated  dog 
were  bitten  by  a  rabid  dog. 

On  June  6th  the  rabid  dog  died,  and  virus  was  taken 
from  it  and  by  trepanation  inoculated  into  3  vaccinated 
and  3  non-vaccinated  dogs. 

On  June  loth  i  vaccinated  and  i  non- vaccinated  dog 
were  bitten  by  another  rabid  dog. 

On  June  17th  i  vaccinated  and  i  non-vaccinated  dog 
were  bitten  by  one  of  the  non-vaccinated  dogs,  which 
had  become  rabid  after  the  inoculation  by  trepanation 
on  June  ist 

On  June  20th  6  vaccinated  and  4  non-vaccinated  dogs 
were  inoculated  by  injection  into  a  vein. 

On  June  28th  2  vaccinated  and  2  non-vaccinated  dogs 
were  bitten  by  a  rabid  dog. 

The  commission  reported  that  of  the  19  non-vac- 
cinated dogs  3  out  of  6  bitten  became  rabid,  5  out  of  7 
inoculated  into  a  vein  became  rabid,  and  all  the  5  in- 
oculated by  trepanation  became  rabid,  but  among  the 


248 


THE   MEDICAL  RECORD. 


[August  30,  1884. 


23  vaccinated  dogs  not  one  single  case  of  hydrophobia 
occurred. 

One  of  the  vaccinated  dogs  died  on  July  13th  from 
diarrhie  noire.  At  once  some  virus  was  taken  from  this 
dog  and  inoculated  by  trepaning  into  three  rabbits  and 
one  Indian  pig.  All  these  four  animals  are  still  quite 
well,  which  is  a  certain  proof  that  the  dog  did  not  die 
from  hydrophobia.  The  commission,  of  its  own  accord, 
now  intend  to  vaccinate  twenty  dogs  in  order  to  ascer- 
tain results  independently  of  M.  Pasteur. 

Professor  Pasteur  finished  his  address  by  stating  that 
animals  are  proportionately  less  infected  by  bites  from 
dogs  than  by  inoculation.  He  emphasized  that  his  experi- 
ments had  only  produced  results  concerning  animals,  but 
that  he  considered  it  most  likely  that  if  the  dog  could 
thus  be  made  insusceptible  of  hydrophobia,  the  source 
of  this  terrible  disease  in  man  would  be  extirpated,  and 
the  question  as  to  prophylaxis  both  for  dog  and  man 
would  be  solvedt 

Sir  Wm.  Gull's  address  on  the  importance  of  a  collec- 
tive investigation  was  well  received  although  it  dealt 
largely  with  truisms  that  were  well  appreciated  by  all 
progressive  men.  The  adoption  of  the  recommendation 
for  a  National  Investigation  Committee  was  a  foregone 
conclusion.  The  selection  was  made  from  the  different 
countries  as  follows,  and  at  the  next  meeting  of  the 
Congress  in  Washington,  there  will  probably  be  formulated 
some  acceptable  working  plan.  The  representatives  for 
the  different  countries  were  :  For  America — Drs.  Jacobi, 
Austin  Flint,  and  Billings ;  Fngland — Sir  James  Paget, 
Acklan,  Gull,  Risdon  Bennett,  Mahomed,  and  Isambord 
Owen  ;  for  Germany — Ewald  and  Guttman  ;  Norway--* 
Bull ;  Denmark — Find  and  Panum  ;  France — ^Verneuil, 
and  Lepine. 

It  was  surprising  to  note  the  busy  character  of  the 
members  in  attendance  at  the  different  general  meetings 
and  at  the  sessions  of  the  sections.  The  attendance  in 
all  was  large,  and  yet  each  listener  was  interested,  and 
all  this  despite  the  thousand  and  one  aUurements  from 
the  municipal  authorities  and  citizens  generally  for 
purely  social  enjoyments.  But  there  was  time  left  for 
these.  The  Tivoli  Gardens  was  the  great  centre  of 
attraction.  There  was  dancing,  concerts,  and  other 
varieties  of  light  amusement,  and  thither  the  majority  of 
the  socially  inclined  repaired  after  the  hard  work  of  the 
day  and  evening.  During  the  Congress  a  public  lunch- 
eon was  provided  free  of  expense  to  the  members,  while 
public  dinners  were  given  every  day  by  invitations.  All 
the  museums  and  hospitals  were  also  thrown  open  to 
the  members. 

In.  my  first  cable  I  alluded  to  a  slight  confusion  in  the 
programme,  but  this  was  only  manifest  during  the  first 
day,  as  afterward  the  affairs  of  the  Congress  progressed 
like  clockwork,  with  nothing  in  the  way  of  unpleasant 
discussion  or  obstructive  jar  to  mar  the  interest  and 
harmony  of  the  notable  eighth  session  of  the  Interna* 
tional  Congress. 


OUR  LONDON   LETTER. 

(From  our  Special  Correspondent.} 

THE   DULL   SEASON — BRITISH  VERSUS   CONTINENTAL   SPAS 

— ^THEIR      LOSS      OUR      GAIN CHOLERA QUARANTINE 

HORRORS — CUSTOM-HOUSE   TROUBLES — DEATH    OF   SIR 
ERASTUS   WILSON. 

London,  August  16, 1884. 

There  is  not  much  stirring  just  now  in  medical  London. 
The  medical  schools  are  closed  till  October.  Most  of 
the  societies  closed  some  months  ago.  All  the  doctors 
who  can  have  followed  the  example  of  their  patients  and 
rushed  off  cither  to  the  mountains,  the  moors,  the 
country,  or  the  seaside.  Our  British  health  resorts  are 
more  than  usually  crowded  this  year,  owing  to  the  presence 
of  cholera  on  the  continent.  Many  people  who  have 
hitherto  paid  regular  visits  to  some  of  the  continental 


spas  every  summer  have  been  obliged  to  Xxy  and  find  a  sub- 
stitute this  year  in  some  of  our  own  watering-places.  The 
present  season  therefore  promises  to  be  a  very  profitable 
one  to  the  inhabitants  of  our  health  and  holiday  resorts 
— most  of  them  are  crowded.  At  many  seaside  places 
bathing  begins  at  four  a.m.  and  goes  on  actively  until  the 
afternoon;  at  some,  bathers  may  be  observed  literally 
"from  early  mom  till  dewy  eve."  Undoubtedly  many 
even  of  those  professedly  in  search  of  health  are  not  in- 
valids in  any  sense  of  the  word ;  but  a  certain  proportion 
of  them  are,  and  a  good  many  fees  are  thus'likely  to  drop 
into  the  pockets  of  our  own  medical  men  that  would 
otherwise  find  their  way  into  those  of  our  forei^  brethren. 

The  loss  to  the  Continental  spas  is  very  senous.  Some 
rough  estimate  may  be  formed  of  it  from  the  diminution 
in  the  number  of  circular  notes  issued  this  year.  One 
bank  alone  estimates  that  up  to  now  it  has  issued  tliree 
thousand  notes  less  than  the  average  of  former  years. 
Multiply  this  by  the  average  amount  represented  by  each 
note,  and  apain  by  the  number  of  banks  issuing  notes,  and 
the  total  will  be  a  good  round  sum. 

The  cholera  is  not  the  only  deterrent  to  foreign  travel 
The  fear  of  quarantine  and  its  discomfits  is  a  greater 
one  even.  Those  who  have  had  to  submit  to  it  are  not 
slow  to  publish  their  sufferings  in  the  daily  newspapers 
as  a  warning  to  others.  Foreign  travel  has  enough  dis- 
comforts already  without  this  added.  The  custom-house 
officers  are  not  usually  remembered  with  kindly  feelings 
by  British  travellers.  Some  years  ago  a  relative  of  the 
writer's,  who  was  travelling  in  Italy  in  medical  charge  of 
an  English  family,  had  an  annoying  experience.  He 
carried  with  him  a  small  medicine-chest  On  the  frontier 
the  diligence  stopped  as  usual,  and  the  passengers  all 
alighted  to  have  their  baggage  examined.  The  medicine- 
chest  was  seized.  In  vain  its  owner  protested  it  only 
contained  medicines.  The  officials  were  inexorable. 
Finally  he  asked  them  to  taste  the  medicines  that  they 
might  be  convinced  of  their  nature.  The  invitation  was 
not  accepted,  and  the  medicines  were,  after  a  long  parley 
in  the  dusty  road,  finally  allowed  to  pass.  Their  owner 
afterward  learnt  that  what  he  ought  to  have  done  was 
to  have  given  the  custom-house  officer  a  "  tip  "  and  then 
he  would  have  had  no  trouble. 

Sir  Erasmus  Wilson  died  last  week  at  his  residence  in 
Kent.  He  was  bom  in  1809,  and  became  a  member  of 
the  College  of  Surgeons  in  1831,  and  a  Fellow  in  1843. 
He  originally  resolved  to  be  a  general  surgeon,  and  be- 
came Assistant-Surgeon  to  St  Bartholomew's  Hospital. 
He  was  the  author  of  the  well-known  '*  Anatomist's  Vade- 
Mecum,''  which  ha«  passed  through  nearly  a  dozen  edi- 
tions, the  last  of  which  was  issued  only  a  few  years  since. 
Twenty  years  ago  it  was  perhaps  the  most  popular  ana- 
tomical text-book  extant,  and  has  sold  well  down  to  the 
present  time.  Not  meeting  with  a  success  equal  to  his 
wishes  in  the  field  of  pure  surgery.  Sir  Erasmus  (then 
simply  Mr.)  Wilson  was  advised  to  take  up  the  skin  as  a 
specialty.  This  he  did  with  the  determination  to  succeed. 
His  success  was  such  that  his  name  has  become  a  house- 
hold word,  and  his  practice  literally  became  enormous. 
Although  married,  he  had  no  family,  and  he  gave  away  a 
large  portion  of  his  earnings.  He  endowed  a  chair  of 
pathology  in  the  College  of  Surgeons  (to  which  he  was 
elected  as  the  first  professor),  and  another  quite  recently 
in  the  University  of  Aberdeen.  The  new  wing  of  the 
Margate  Sea  Bathing  Infirmary  was  built  with  a  donation 
presented  by  Mr.  Wilson.  His  gifts  to  various  charities 
would  take  some  time  to  enumerate.  I  need  scarcely 
remind  your  readers  that  he  brought  Cleopatra's  Needle 
to  England,  an  exploit  which  cost  him  ten  thousand 
pounds. 

Mr.  Wilson  never  held  any  skin  appointment  (except 
for  a  short  time  the  purely  honorary  one  of  Consulting 
Surgeon  to  the  St  John's  Hospital  for  Skin  Diseases),  so 
his  experience  was  drawn  from  private  practice,  but  as 
this  was  so  large  he  did  not  feel  the  want  of  a  hospital 
clinic.     "  1  see  specimens  of  most  varieties  of  skin  dis- 


August  30,  i884,] 


THE  MEDICAL  RECORD. 


249 


ease  here^  he  once  remarked  to  a  medical  friend,  look. 
ing  round  his  spacious  consulting  room.  He  lived  and 
practised  for  many  years  next  door  to  the  late  Sir  Thomas 
Watson.  He  was  President  of  the  College  of  Surgeons 
in  188 1,  and  he  received  the  honor  of  knighthood  in  the 
same  year.  He  lived  virtually  retired  during  the  last 
two  years  of  his  life  at  his  house  at  Westgate.  He  was 
the  author  of  numerous  works  on  dermatology. 


THE  MORPHOLOGICAL  STATUS  OF  THE 
CEREBELLUM. 

To  THB  EcrroK  op  Thb  Mkdical  Rscoiu). 

Sir  :  Permit  me  to  ask  your  readers  not  to  interpret  my 
silence  respecting  Dr.  Spitzka's  letter  under  the  above 
title  (The  Medical  Record,  July  26,  1884)  as  indicat- 
ing either  that  I  have  abandoned  the  view  attributed  to 
me,  or  that  I  am  unaffected  by  the  objections  so  ably 
advanced  by  that  distinguished  anatomist. 

I  say  the  view  attributed  to  me^  because  Dr.  Spitzka 
does  not  refer  to  the  fact  that  in  my  discussions  of  the 
segmental  constitution  of  the  brain  {Science^  March 
19,  1881,  p.  135;  "The  Brain  of  the  Cat,"  "Pro- 
ceedings Am.  Phil.  Soc,"  August  15,  1881 ;  Anaiom- 
icai  Technology^  November,  1882,  pp.  405,  479,  482  ; 
"Cartwright  Lectures,"  several  places  in  Lecture  I.)  I 
\as^  provisionally  followed  Von  Baer  and  others  in  rec- 
ognizing the  existence  of  two  encephalic  segments  can- 
did of  the  "  optic  lobes." 

The  matter  will  be  more  fully  considered  in  the  last 
part  of  the  third  **  Cartwright,"  and  forms  the  subject  of 
a  paper  entitled  "  Do  the  Cerebellum  and  the  Oblon- 
gata represent  One  Encephalic  Segment  or  Two  ?  "  for 
presentation  at  the  coming  meeting  of  the  American  As- 
sociation for  the  Advancement  of  Science,  in  Philadel- 
phia. If  Dn  Spitzka  could  attend  the  meeting,  it  would 
not  only  gratify  me  but  further  the  solution  of  a  difficult 
problem.  Burt  G.  Wilder,  M.D. 


AN  UNNOTICED   FEATURE   OF   THE   GROSS 
ANATOMY  OF  THE  FOURTH  VENTRICLE. 


To- 


:  Editor  op  TuB.BiBMCAL  Rxcosoi. 


Sir  :  Observers  of  cerebral  anatomy  are  familiar  with  the 
fine  longitudinal  striations  which  appear  to  pass  from  the 
anterior  half  of  the  fourth  ventricle  to  the  aqueduct,  to- 
ward which  they  conveige.  It  is  not  determined  whether 
they  are  the  result  of  shrinkage,  through  the  action  of 
hardening  fluids;  they  seem  to  be  most  pronounced  in 
those  parts  of  the  ventricular  parietes  where  laige  cavi- 
ties undergo  a  sudden  contraction  in  passing  into  smaller 
channels,  such  as  the  infundibulum  and  the  locality  above 
mentioned.  Bergmaun  gave  a  special  name  to  Uiose  in 
the  latter  situation,  terming  them  Psalterium  and  Or- 
ganon  pneunuUicuM.  In  no  treatise,  ancient  or  modern, 
do  I  find  a  veiy  distinct  appearance,  which  I  have  fre- 
qaently  noted,  described  In  the  lateral  angles  of  the 
fourth  ventricle  of  a  child  aged  fourteen  months  I  found 
OD  either  side  three  button-Uke  elevations,  into  which  the 
striae  described  by  Bergmann  were  continued,  just  as  the 
stick  of  a  drumstick  joins  its  button-like  termination. 
In  another  child  their  existence  in  the  fresh  (unhard- 
cncd)  brain  was  determined.  They  are  paler  than  the 
rest  of  the  ventricular  flow  in  chromic  acid  preparations. 
At  first  I  supposed  that  these  elevations  were  infantile 
features  in  the  human  brain,  like  ihe  crista  fornicis  of 
Wilder,  which,  so  far  as  I  am  aware,  has  been  identified 
hythat  observer  only  in  a  child.  On  examining  the 
fourth  ventricle  of  the  negro  Jefiferson,  recently  executed 
in  Brooklyn,  I  found  these  "hordea,*'  as  I  propose  to 
designate  them,  very  distinctly  marked.  On  the  right 
side  there  were  two  of  these  prominences,  globular,  sep- 
arated by  a  narrow  fissure^  the  aggregate  dunensions  be- 
ing, antero-posteriorly,  a  little  over  one-eighth  of  an 
inch,  each  measuring  transversely  a  sixteenth.     On  the 


left  side  there  was  a  single  eminence  apparently  equiva- 
lent to  a  fusion  of  two  such  as  those  on  the  other  side  ; 
it  resembled  a  long  oval  hill,  running  antero-posteriorly, 
with  its  anterior  end  making  a  deflection  inward.  In  the 
several  brains  in  which  I  have  identified  these  bodies 
they  were  all  situated  directly  laterad  of  Ha^forea.  In 
the  negro,  most  of  the  strias  of  the  psalterium  passed 
laterad  of  them,  along  the  rising  ventricular  side-wall  to 
pass  into  the  roof  of  the  ventricle.  A  few,  however, 
passed  toward  the  hordea,  but  without  as  distinctly  con- 
necting with  them  as  in  the  infantile  brains.  In  one  of 
the  latter,  the  three  beautifully  distinct  hordea  (resem- 
bling, as  their  name  indicates,  so  many  barleycorns)  of 
each  side  had  each  a  string  of  the  psalter  running  into 
them,  so  as  to  resemble  (as  above  indicated)  three  thick- 
headed drumsticks  lying  side  by  side.  In  several  hard- 
ened specimens  of  the  adult  brain-isthmus  I  find  these 
bodies  to  be  as  distinct  as  in  the  negro  cited,  alcohol 
specimens,  as  a  rule,  showing  them  less  distinctly  than 
such  as  had  been  first  preserved  in  acid,  chromic  salts, 
or  glycerine  mixtures. 

What  the  significance  of  these  bodies  is,  whether  they 
be  mere  thickenings  of  the  end3m3a  or  not,  I  am  unable 
at  present  to  say.  I  have  identified  faint  indications  of 
these  bodies  in  the  corresponding  situation  in  the  sea- 
lion  and  found  them  absent  in  one  monkey  (cercopithe- 
cus),  butfnot  having  examined  the  entire  collection  with 
reference  to  this  point,  am  unable  to  say  anything  as  to 
the  general  absence  or  presence  of  the  hordea  in  the  an- 
imal scale. 

I  may  remark  in  conclusion,  that  the  general  physiog- 
nomy— if  I  may  so  term  it— -of  the  fourth  ventricle  in  the 
negro  referred  to,  was  more  infantile  than  that  of  any 
other  human  brain  I  have  examined.  The  floor  of  this 
cavity  in  the  child  is  marked  by  the  deep  depression  of 
the  so-called  "fasciculus  teres*'  elevation,  the  outer  bor- 
ders of  the  distinct  grooves  on  the  outer  side  rising  up 
very  steep.  In  the  adult,  ordinarily,  the  floor  becomes 
generally  flatter.  The  general  development  of  this  ne- 
gro's brain  was  good.  £.  C.  Spftzka,  M.D. 


ENDORSED   DIPLOMAS   OF  THE   UNITED 
STATES  MEDICAL  COLLEGE. 

To  TKB  EdUOR  op  TtaS  MXDICAL  RacosD. 

Sir:  Inasmuch  as  numerous  inquiries  have  been  ad- 
dressed to  the  Board  of  Censors  of  the  County  Society 
in  regard  to  the  endorsement  of  diplomas  by  the  United 
States  Medical  College,  we  have  been  advised  to  answer 
the  following  recent  inquiries  through  The  Record  : 

I.  Is  the  Eclectic  Medical  College  of  Cincinnati,  O., 
a  reputable  institution  ? 

3.  Is  a  diploma,  issued  by  the  above,  and  endorsed  b^ 
R.  A.  Gunn,  legal  qualification  for  the  practice  of  medi- 
cine? 

If  the  writer  refers  to  the  Eclectic  Medical  Institute  of 
Cincinnati,  it  is  a  reputable  school  and  the  diplomas  are 
recognized  by  the  Illinois  State  Board  of  Health,  pro- 
vided the  graduate  presents  a  written  statement  firom  the 
dean  that  he  has  studied  medicine  three  years,  and  taken 
two  full  courses  of  twenty  weeks  each,  extending  over  a 
period  of  sixteen  months.  The  natural  inference  from 
this  condition  is  that  diplomas  have  been  issued  from 
said  college  to  persons  who  have  not  met  these  require- 
ments, but  that  the  present  management  is  entitled  to 
confidence.  The  Court  of  Appeals  has  declared  that  the 
United  States  Medical  College  was  illegally  incorporated, 
and  such  disability  never  having  been  removed  by  subse- 
quent legislation,  every  diploma  issued,  and  every  en- 
dorsement by  R.  A.  Gunn  as  dean  became  null  and 
void.  As  a  measure  of  relief  to  the  innocent  victims  of 
this  now  defunct  institution,  the  Legislature  last  winter 
passed  an  act  legalizing  the  diplomas  issued  by  the  United 
States  College  prior  to  the  beginning  of  proceedings 
against  it,  April  21.  1883,  provided  the  holders  of  said 


250 


THE  MEDICAL  RECORD. 


[August  30, 1884, 


diplomas  had  attended  the  required  courses  of  lectures, 
passed  a  satisfactory  examination,  and  been  regularly 
graduated,  in  other  words  had  not  secured  a  diploma  by 
the  disreputable  means  believed  to  have  been  practised 
in  some  instances. 

Very  respectfully, 

Daniel  Lewis,  M.D., 
Chairman  of  Board  of  Censors. 


ELECTROLYSIS  IN  STRICTURE. 

To  THK  Editor  op  Thb  Mbdical  RxooRa 

Sir  :  Allow  me  a  few  words  in  reply  to  a  criticism  in  the 
last  Record  of  my  article  on  the  above  subject  by  Dr. 
Meier.  I  do  not  propose  to  enter  into  any  controversy 
upon  this  subject,  and  this  will  close  the  discussion  on 
my  part  For  it  is  apparent  from  the  doctor's  attempted 
contradiction  of  my  position,  that,  in  the  words  of  a  dis- 
tinguished surgeon,  "it  is  useless  to  argue  with  men  who 
persist  in  making  statements  in  direct  opposition  to 
those  who  are  known  to  have  the  largest  opportunities 
for  scientific  investigation  and  experience.'' 

I  claimed  that  it  is  impossible  to  cure  organic  stricture 
by  the  method  of  which  we  have  heard  considerable  in 
the  last  few  years,  namely,  the  application  of  electric 
currents  so  weak  as  to  be  scarcely  felt  That  it  was  not 
to  be  expected  from  our  knowledge  of  the  laws  of  elec- 
tro-therapeutics, and  was  not  endorsed  by  the  standard 
authorities.  My  "arbitrary  dictum,"  as  the  doctor  terms 
it,  is  based  upon  nearly  twenty  years'  experience  in  the 
study  and  treatment  of  strictures  and  in  the  use  of  elec- 
tricity. Any  one  can  read  the  authorities  for  themselves. 
Sir  Henry  Thompson,  Surgeon  to  University  College 
Hospital,  London,  and  Fessenden  N.  Otis,  Professor  of 
Genito-Urinary  Diseases  in  the  College  of  Physicians 
and  Surgeons,  and  Surgeon  to  Charity  Hospital,  New 
York,  authors  of  the  most  classical  works  upon  stricture 
which  have  ever  been  written,  and  who  have  probably 
had  the  largest  experience  in  this  line  of  any  men  who 
ever  lived,  totally  ignore  electrolysis.  "  Althaus,"  the 
great  English  authority  on  electricity,  and  "  Beard  and 
Rockwell,"  the  American,  speak  in  very  guarded  and  not 
favorable  terms  of  the  remedy.  And  so  one  might  go 
through  nearly  the  whole  list  of  standard  writers,  college 
professors,  and  hospital  surgeons,  who  have  had  the 
greatest  opportunities  for  studying  and  experimenting. 
Their  ability  or  honesty  cannot  be  questioned;  theu: 
position  certifies  to  the  one,  and  their  character,  writings, 
and  the  absence  of  biasing  motives  to  the  other.  'The 
doctor  claims  that  analogous  conditions  in  other  parts 
are  cured  in  this  way.  The  above  remarks  apply  equally 
to  this  statement  also.  S.  W.  Gross,  Professor  of  Sur- 
gery in  the  Jefiferson  Medical  College,  Philadelphia,  in  a 
recent  elaborate  article  in  the  American  Journal  of  the 
Medical  Sciences  on  the  "  Treatment  of  Stricture  of  the 
CEsophagus,"  does  not  even  mention  electricity.  And 
yet  my  critic  has  the  assurance  to  deny  all  this  and  claim 
that  the  writer,  and  if  him  then  all  who  agree  with  him, 
which  embraces  the  great  mass  of  the  profession,  are  not 
sufficiently  skilful  to  follow  the  directions  laid  down  by 
the  advocates  of  this  method.  But  that  the  method  itself 
is  all  right  is  not  proven  because  a  certain  doctor  does 
succeed  with  it  anyhow,  no  matter  whether  any  one  else 
does  or  not. 

In  support  of  his  statements  he  quotes  a  few  of  the  re- 
ports of  the  remarkable  effects  of  electricity  which  have 
appeared  in  the  journals.  All  have  heard  this  same  kind 
of  argument  before,  can  weigh  the  evidence  of  both  sides, 
make  the  "  experimentum  crucis"  for  themselves,  and 
draw  their  own  conclusions.  My  experience  with  dilata- 
tion, divulsion,  electrolysis,  and  dilating  urethrotomy, 
leads  me  to  believe  that  very  few  cases  of  stricture  are 
permanently  cured,  except  by  tearing  (divulsion)  or  cut- 
ting ;  and  the  former  process  has  generally  been  aban- 
doned as  having  no  advantages  and  some  disadvantages 


compared  with  the  cutting  operation.  Nearly  every 
stricture  of  the  straight  urethra  should  be,  and  can  be 
cured  permanently  by  cutting.  An  external  constricting 
band  or  a  contracted  meatus  is  cut  unhesitatingly.  ^ 
puttmg  the  urethra  on  the  stretch  by  the  urethrotome  an 
internal  one  is  cut  with  nearly  equal  facility  with  little  or 
no  pain  and  with  almost  perfect  safety.  "  Operations  con- 
fined to  the  straight  urethra  are  tfj  a  rule  never  followed 
by  constitutional  disturbance,"  but  no  instruments  should 
be  passed  into  the  bladder  at  the  same  time,  for 
the  passage  of  a  sound  not  unfrequently  causes  chills 
and  other  constitutional  effects.  The  rationale  of  cure 
is  by  relieving  spasm  and  congestion,  which  must  exist 
more  or  less  about  every  stricture,  to  promote  a  healthy 
circulation  and  absorption  of  the  deposit.  Over  1,100 
cases  without  a  death,  and  with  only  a  very  few  cases  of 
urethral  fever,  serious  hemorrhage,  or  inflammation,  and 
these  few  in  operations  on  the  deep  urethra,  are  reported 
in  Otis'  work.  It  is  not  until  we  pass  around  the  pubic 
curve  that  trouble  usually  begins.  Fortunately  the  great 
majority  of  cases  are  in  the  straight  urethra,  slight  con- 
tractions of  which  the  only  symptom  is  gleet,  with  more 
or  less  spasmodic  contractions  deeper.  ''These  cases 
are  of  daily  occurrence  and  often  pass  unrecognized,  the 
gleet  being  treated,  the  stricture  overlooked.  Too  much 
stress  cannot  be  laid  upon  the  importance  of  exploring 
the  urethra  in  every  such  case,  and  if  the  slightest  ob- 
struction is  found,  removing  it." 

H.  W.  Streeter,  M.D. 

X04  WcsT  Main  Stkkbt,  Rochester,  N.  V. 

Official  List  of  Changesin  theStaiUms  and  Duties  of  Officers 
serving  in  the  Medical  Departnunt^  United  States  Army, 

from  August  17  to  August  23,  1884. 

Crampton,  I>ouis  W.,  Captain  and  Assistant  Surgeon. 
To  report  at  Creedmoor  (L.  I.),  N.  Y.,  not  later  than 
August  30th,  as  competitor ;  and  in  addition  thereto,  as 
medical  officer  of  the  detachment  of  competitors.  S.  0. 
41,  Division  of  the  Atlantic,  August  20,  1884. 

Cochran,  J.  J.,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  at  the  Presidio  of  San  Francisco, 
Cal.     S.  O.  81,  Division  of  the  Pacific,  August  16, 1884. 

Birmingham,  H.  P.,  First  Lieutenant  and  Assistant 
Surgeon.  Granted  one  month's  leave  of  absence.  S. 
O.  162,  Department  of  the  Missouri,  August  12,  1884. 

Wilson,  George  F.,  First  Lieutenant  and  Assistant 
Surgeon.  Relieved  from  duty  at  Fort  Walla  Walla, 
Wash.  Terr.y  and  to  take  station  at  Vancouver  Barracks, 
Wash.  Terr.  S.  O.  120,  Department  of  the  Columbia, 
August  13,  1884. 

Fisher,  W.  W.  R.,  .  First  Lieutenant  and  Assistant 
Surgeon.  When  relieved  by  Assistant  Surgeon  Cochran, 
to  report  in  person  to  Commanding  General,  Depart- 
ment of  Arizona,  for  assignment  to  duty  in  that  depart- 
ment.    S.  O.  81,  C.  S.,  Division  of  the  Pacific. 


Woodward,  J.  J.,  Major  and  Surgeon. 
17,  1884. 


Died,  August 


Official  List  of  Changes  in  the  Medical  Carps  of  the  U.  S, 
Navy,  during  the  week  ending  August  23,  1884. 

Rixey,  p.  M.,  Passed  Assistant  Surgeon.  Orders  to  U. 
S.  S.  Lancaster  revoked.     To  continue  on  special  duty. 

Martin,  C,  Medical  Director.  To  be  retired  August 
21,  1884. 

Heyl,  T.  C,  Surgeon.  Detached  from  U.  S.  S.  Inde- 
pendence, ordered  to  U.  S.  S.  Adams. 

Ayers,  J.  G.,  Surgeon.  Detached  from  U.  S.  S,  Adams, 
placed  on  waiting  orders. 

Curtis,  L.  W.,  Assistant  Surgeon.  Detached  from 
U.  S.  S.  Adams,  placed  on  waiting  orders. 


August  30,  1884.] 


THE  MEDICAL  RECORD. 


251 


Stephenson,  F.  B^  Passed  Assistant  Surgeon.  De- 
tached from  Navy  Yard,  New  York,  ordered  to  C.  S.  S. 
Bache. 

Derr,  £•  Z.,  Passed  Assistant  Surgeon.  Detached 
from  C.  S.  S.  Bache,  placed  on  waiting  orders. 

^edical  Stems. 

Contagious  Disxasxs — ^Wxxkly  Statsmxmt. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  die  Sanitary  Bureau,  Health  Department,  for 
die  week  en^ng  August  33,  1884 : 


WaekBndiiif 


Auf^t  16,  1884 
Ai^st  23,  1884 

Dtaiks. 
August  16,  1884 
August  23,  1884 


I 


I 


The  Vagaries    of   a    Needle. — Under  the  above 

head  Dr.  John  Burke,  of  this  city,  writes  :  "  Miss  A , 

seventeen  years  of  age,  came  to  my  office  last  October 
saffering  from  an  abscess  behind  her  right  ear,  over  mas- 
toid process.  She  had  this  trouble  for  four  years,  and 
for  ten  years  she  had  a  discharge  from  her  ear,  sometimes 
fetid  and  sometimes  not.  She  was  also  partially  deaf  in 
that  ear.  Her  mother  had  tried  many  ear  surgeons,  but 
the  discharge  from  the  ear  and  the  deafness  continued. 
Now,  the  abscess  had  two  openings,  one  above  and  the 
other  directly  below,  about  one  inch  apart  Under 
ether  I  laid  open  the  parts  to  the  bone.  There  was  no 
Deaosis.  Next  day  a  poultice  of  flax-seed  meal  was  ap- 
plied. In  three  days  a  common  sewing-needle  came  out 
of  the  wound,  not  much  rusted.  History :  Ten  years 
ago  the  child,  being  seven  years  of  age,  was  playing  with 
a  needle  in  her  mouth ;  it  was  swallowed.  It  caused 
some  strangulation.  It  could  not  be  found  by  the  doc- 
tors who  examined  the  throat.  About  four  months  after- 
ward the  child  was  taken  with  pain  in  the  ear  and 
otorrhoea,  which,  notwithstanding  good  surgical  treat- 
ment, continued  for  ten  years.  For  four  years  she 
suffered  with  an  abscess  over  mastoid  process,  sometimes 
healing,  and  then  suddenly  breaking  out.  On  March 
ist  the  needle  came  out.  Since  then  the  abscess  has 
healed,  the  discharge  from  the  ear  has  ceased,  and  the 
patient  can  hear  very  fairly  in  the  ear,  but  not  as  well  as 
in  the  other  side.     But  all  pain  and  tenderness  has  gone." 

Ovariotomy  in  the  Corpulent  ;  Ovarian  Cyst  in 
A  Woman  aged  Ninety. — Dr.  W.  P.  Giddings,  of 
Gardiner,  Me.,  sends  us  the  following  instructive  his- 
tories :  "On  June  26,  1882, 1  removed  from  Mrs.  S , 

twenty-six  years  of  age,  an  ovarian  multilocular  cyst, 
weighing  with  its  contents  flfty  pounds.  She  had  been 
tapped  four  times,  the  last  two  by  myself,  removing 
respectively  33  and  35  pounds.  The  abdomen  was  ex- 
cessively pendulous,  and  after  closing  the  wound  there 
was  a  very  deep  sulcus  into  which  I  judge  a  pint  of  fluid 
noigfat  have  been  poured  and  retained.  Desiring  to  avoid 
the  retention  and  burrowing  of  pus  about  the  wound,  I 
placed  adhesive  strips  to  within  half  an  inch  of  the 
wound  and  drew  them  around  toward  the  spine,  then 
crossed  the  wound  with  adhesive  straps  supporting  it  in 
the  usual  way.  I  had  the  cicatrix  thus  supported  for 
several  months,  reinforced  by  the  bandage.  Recovery 
was  oninterrapted,  and  there  was  gradual  retraction  of 
skin  and  muscles  to  a  normal  state.     On  June  i6th  of 


the  present  year,  I  delivered  the  lady  of  a  fine  healthy 
boy  of  10  pounds  weight,  and  found  the  cicatrix  of  wound 
had  not  yielded  in  the  slightest  degree,  and  during  labor 
there  seemed  to  be  sCs  much  force  exercised  by  the 
muscles  as  is  usual     Convalescence  rapid  and  complete. 

Case  2  :  Mrs.  A ,  ninety  years  of  age,  had  for  eighteen 

months  noticed  a  gradual  enlargement  of  abdomen, 
and  for  some  few  months  oedema  of  feet  and  limbs, 
which  had  greatly  increased,  rendering  locomotion  im- 
possible, and  confining  her  to  bed.  To  add  to  her  dis- 
comfort, profuse  salivation  had  come  on,  preventing  her 
taking  food  or  getting  sleep.  General  dropsy  had  been 
diagnosed,  and  I  was  called  in  consultation.  There  had 
been  at  times  during  the  past  few  months  quite  a 
"  show.''  I  instituted  a  careful  examination  and  diag- 
nosed ovarian  cyst  of  left  side  with  thin  fluid.  The  case 
was  frankly  stated  and  tapping  advised,  her  extreme  age 
forbidding  the  thought  of  a  radical  operation.  The  old 
lady,  unusually  intelligent,  with-  faculties  remarkably  well 
preserved,  submitted  at  once  to  the  operation,  remarking 
during  it,  "Doctor,  I  enjoy  seeing  that  fluid  run; 
surgery  has  advanced  since  I  was  a  girl.'*  This  was  done 
April  10,  1884.  At  present  writing  she  is  well  and 
hearty,  though  the  cyst  is  gradually  filling.  Who  has 
seen  so  old  a  person  develop  an  ovarian  tumor  ?  " 

A  New,  Successful,  and  Palatable  Medicine  for 
THE  Treatment  of  Tape-worm. — Under  the  above  title 
Dr.  Howard  Pinkney,  writing  from  Sharon  Springs,  de- 
scribes his  experience  with  the  oil  of  the  pine  needle, 
made  from  the  pinus  punilio,  A  hall-boy  of  the  hotel 
had  sufiered  for  five  years  from  tape-worm.  He  had 
been  treated  for  four  years  in  New  York,  but  never  had 
succeeded  in  getting  rid  of  over  four  feet  of  links  at  a 
time.  Dr.  Pinkney  not  being  able  to  get  any  male  fern, 
pelletierine,  or  pumpkin  seeds,  therefore  tried  the  fol- 
lowing experiment :  "The  patient  fasted  from  breakfast, 
and  at  nine  p.m.  he  was  given  one  teaspoonfiil  of  oil  of 
the  pine  needle  in  half  a  glass  of  milk.  The  following 
morning,  as  there  was  no  perceptible  action  of  the  medi- 
cine, the  dose  was  doubled.  This,  the  boy  said,  had  a 
most  agreeable  taste.  One  hour  later  he  took  a  dose  of 
castor  oil,  and  in  the  course  of  two  hours  after  this  he 
passed  an  entire  tasnia  solium  measuring  fifteen  feet  six 
inches  in  length  and  one-half  inch  at  its  broadest  part, 
gradually  tapering  down  to  almost  a  thread.  To  be  positive 
that  none  remained  behind,  he  was  given  two  teaspoon- 
fills  more,  but  no  sign  of  any  worm  or  part  thereof 
passed.  This  oil,"  writes  Dr.  Pinkney,  "  contains  no  tur- 
pentine, is  fragrant  in  its  odor,  and  when  mixed  with  milk 
very  agreeable  to  the  taste.  It  produces  no  strangury, 
tenesmus,  or  other  unpleasant  or  distressing  symptoms. 
The  patient  can  generally  pursue  his  ordinary  avocation." 
Our  correspondent  would  be  pleased  to  know  if  any  of  our 
readers  have  ever  read  or  known  of  its  use  in  similar  cases. 

The  Cholera  Germ  and  its  Destruction. — Dr. 
Koch  has  found  large  numbers  of  diflerent  kinds  of 
germs  in  the  intestines  and  discharges  of  cholera  patients, 
and  among  them  one  almost  new  kind  which  seems  peculiar 
to  cholera.  This  form,  which  was  not  round,  or  dot-like, 
nor  rod-shaped,  had  been  previously  noticed  and  described 
by  Dr.  Bristowe,  of  England,  a  well  known  medical 
author,  as  early  as  1867.  Other  more  common  forms 
of  germs  were  found  in  the  dejecta  and  intestines  by 
Bohm  as  early  as  1838.  Round  or  dot-like  bodies  were 
detected  by  Brittain  and  Swayne  in  Bristol,  England, 
in  1849,  2md  confirmed  by  Hugh  Bennett,  of  Edinburgh. 
Pouchet,  Davaine,  and  Paccini  saw  them  again  in  1854 
and  1856.  Dundas  Thompson  and  Dr.  Hassell,  quoted  in 
the  United  States  Cholera  Report  for  1873,  ^so  wrote 
about  them  in  1854,  and  stated  that  they  thrived  most  in 
warm  alkaline  fluids,  when  contaminated  with  organic 
matter  in  a  state  of  decomposition.  The  rice-water  dis- 
charges of  cholera  were  found  to  be  alkaline  and  very 
prone  to  putrefaction,  and  acids  were  first  suggested  as 
germicides  and  as  curative  remedies  for  cholera.     In 


25^ 


THE  MEDICAL  RECORD. 


[August  30, 1884. 


1866  Dr.  MacNaimara,  one  of  the  very  best  writers  on 
cholera,  noticed  the  same  things  and  was  inclined  to  be- 
lieve that  the  cholera  germs  died  naturally  in  about  three 
days.  In  1872,  Nedwetsky,  also  quoted  in  the  United 
States  Cholera  Report  for  1873,  p.  32,  ^ave  us  still  more 
positive  information.  He  put  ten  grams  of  quinine  in 
two  teaspoonfuls  of  rice-water  discharges  which  were 
swarming  with  germs,  and  they  were  not  only  alive 
on  the  second  and  third  days,  but  by  the  fifth  day  large 
masses,  or  new  colonies  of  them,  had  formed.  He 
then  put  thirty  grains  of  camphor  in  two  teaspoonfuls  of 
rice-water  cholera  discharges  and  found  that  the  germs 
lived  and  thrived.  Next  he  put  five  drops  of  strong  car- 
bolic acid  in  two  teaspoonfuls  of  nce-water  discharges, 
but  the  germs  remained  alive  and  active.  On  the  fifth 
day  he  added  five  drops  more  of  carbolic  acid  but  did 
not  kill  the  germs.  Then  he  put  first  one  teaspoonful 
and  then  two  teaspoonfuls  of  tar  in  two  teaspoonfuls  of 
rice-water  discharges,  but  the  germs  continued  to  live, 
move  and  thrive.  Then  he  put  ten  grains  of  calomel  in 
two  teaspoonfuls  of  rice-water  discharges,  but  the  germs 
continued  to  live  and  move  among  the  particles  of  calo- 
mel which  had  settled  at  the  bottom  of  the  glass ;  and  by 
the  fifth  or  sixth  day  great  numbers  and  masses  of  new 
germs  had  formed.  Then  he  put  one  teaspoonful  of 
laudanum  in  two  teaspoonfuls  of  rice-water  discharges, 
but  the  germs  were  alive  on  the  second  and  third  days, 
and  on  the  sixth  day  only  a  few  of  them  were  benumbed. 
Next  he  put  one  teaspoonful  of  tincture  of  nux  vomica  in 
two  teaspoonfuls  of  rice-water  discharges,  but  most  of 
the  germs  lived  up  to  the  tenth  day,  and  then  only  a 
portion  of  them  were  dead  and  motionless.  One  tea^ 
spoonful  of  chloral  was  put  in  two  teaspoonfuls  of  rice- 
water  discharges,  but  the  germs  were  not  killed. 

If  there  is  any  value  in  such  careful  and  ingenious  ex- 
periments they  seem  to  prove  that  all  these  powerful 
remedies   are  useless  in   cholera.     Nedwetsky  was  in- 
clined to  believe  that  they  might  be  useful  in  cholera 
morbus  and  other  allied  diseases,  and  as  one-half  of  the 
cases  of  real  cholera  recover,  that  they  had  obtained  a 
fictitious  reputation.     He  was  destined  to  be  more  suc- 
cessful with  other  remedies.     He  put  ten  grains  only  of 
tannin  or  tannic  acid  in  two  teaspoonfuls  of  rice-water 
discharges,  and  in  two  hours  an  innumerable  number  of 
germs  were  found  without  life  or  motion.     None  of  them 
came  to  life  again  up  to  the  tenth  day,  even  after  they 
were  put  in  distilled  water  to  revive  them.     Dilute  sul- 
phuric and  nitric  acids,  made  by  putting  twenty  drops  of 
the  strong  acids  in  an  ounce  of  water,  and  adding  two 
teaspoonfuls  of  this  to  two  teaspoonfuls  of  rice-water 
discharges,  killed  the  germs  at  once.     Very  dilute  mu- 
riatic acid,  made  by  putting  three  drops  only  of  the  strong 
acid  in  six  ounces,  or  nearly  half  a  pint  of  water,  killed 
the  majority  of  the  germs.     Chlorine  water  killed  the 
germs  at  ^once.     Sulphate  of  iron  in  concentrated  solu- 
tion also  killed  the  germs,  and  chloroform  also.     It  is 
now  claimed  that  all  these  germs  were  merely  common 
germs  or  bacteria  such  as  cause  ordinary  putrefaction. 
But  all  the  rice-water  discharges  were  taken  from  well- 
marked  cholera  cases  which  had  been  attended  by  Ned- 
wetsky and  the  others  during  life  and  examined  after 
death.     We  have  apparently  gained  fixed  points  in  the 
treatment  of  Asiatic  cholera,  which  some  are  not  will- 
ing to  surrender.     Healthy  acid  gastric  juice  will  destroy 
the  germs  of  cholera,  and  if  sufficient  of  it  be  present 
in   the  stomach,  rice-water  cholera  discharges  may  be, 
or  at  least  have  been,  swallowed  with  impunity.     In  a 
jail  in  India  some  experiments  were  being  carried  on; 
rice-water  discharges  were  put  in  a  very  large  glass  of 
water;  nineteen  convicts  accidentally  drank  of  this;  in 
consequence  four  or  five  weak  and  dyspeptic  patients 
died  of  cholera  and  the  rest  all  escaped  without  a  sign  of 
disease.     Muriatic  acid  is  the  base  of  the  acidity  of  the 
gastric  juice,  and  common  table  salt  is  a  muriate  of  soda 
or  a  combination  of  muriatic  acid  and  soda.     Sulphuric 
acid  has  a  well-established  reputation  in  the  treatment  of 


cholera.  Koch  has  added  alum,  which  is  a  sulphate  of 
alumina  that  kills  his  germs  in  a  one  per  cent,  solution. 
There  is  no  harm  in  adding  a  little  sulphate  of  morphine 
to  these  remedies,  for  opium  has  much  palliative,  if  not 
curative,  influence  over  cholera.  Sulphate  of  copper  is 
suggested  by  Koch,  who  says  it  will  kill  his  germs  in  the 
very  dilute  solution  of  one  part  to  2,500  of  water.  And 
corrosive  sublimate  in  the  proportion  of  one  to  20,000. 
But  the  great  difficulty  in  the  treatment  of  cholera  lies  in 
the  fact  that  huge  quantities  of  alkaline  fluids  are  poured 
out  into  the  stomach  and  bowels ;  these  have  to  be 
measured  by  quarts  or  gallons  rather  than  by  pints  or 
ounces,  and  all  has  not  only  to  be  neutralized  but  ren- 
dered acid  before  the  germicides  will  act.  If  it  takes  ten 
drops  of  dUute  sulphuric  acid  to  kill  the  germs  in  two 
teaspoonfuls  of  rice-water  discharges,  how  much  will  it 
require  to  deal  with  quarts  at  least :  it  would  seem  that 
rather  large  doses  frequently  repeated  are  required ;  and 
we  can  judge  of  the  frequency  of  the  repetition  of  the 
doses  by  the  use  of  litmus  paper  to  the  discharges;  when 
these  become  acid  the  doses  may  be  lessened.  And  now 
would  also  be  the  time  to  try  the  more  powerful  remedies, 
viz.,  sulphate  of  copper  and  corrosive  sublimate,  if  any 
one  wishes  to  do  it;  they  will  be  inoperative,  though 
alkaline  fluids.  Lemon  juice  and  vinegar  have  always 
been  forbidden  in  cholera,  but  acetic  acid,  the  basis  of 
vinegar,  is  an  efficient  remedy. 

Rectal  Etherization. — Dr.  O.  Wanscher  writes  in 
the  Copenhagen  HospUals^Tidende^  of  May  28,  1884, 
giving  an  account  of  the  history  of  rectal  etherization 
and  of  the  advantages  and  disadvantages  of  this  method. 
He  states  that  in  1847,  immediately  upon  the  introduc- 
tion of  anaesthesia  for  surgical  operations,  Pirogoff  con- 
ceived the  idea  of  administering  ether  for  this  purpose 
by  the  rectum.  Migendie's  experiments  upon  animals, 
however,  demonstrated  the  danger  of  injecting  fluid 
ether  into  the  rectum,  many  of  &e  animals  so  treated 
passine  into  a  state  of  dangerous  or  even  fatal  collapse, 
and  Purogoff"  was  therefore  led  to  experiment  with  the 
vapor  of  ether  passed  into  the  bowels.  The  method  was 
described  by  him  in  a  pamphlet  published  in  St.  Peters- 
burg in  1847,  entitled  "Recherches  sur  T Etherisation," 
and  also  by  Ekstromer  who  recommended  its  employ- 
ment instead  of  tobacco  clysters  in  the  treatment  of 
incarcerated  hermia.  The  latter  used  it  also  with 
success  for  the  relief  of  renal  colic.  But  upon  the  in- 
troduction of  chloroform,  Pirogoff,  together  with  most  of 
the  European  surgeons  abandoned  ether,  and  then  rectal 
anaesthesia  passed  into  oblivion.  The  method  was  re- 
vived again  by  Wanscher,  who  published  an  article  on 
the  subject  in  the  Hospitals'7}dende  in  1882.  The 
apparatus  used  by  him,  which  is  nearly  identical  with 
that  of  Pirogoff,  consists  of  a  bottle  to  which  is  attached 
a  flexible  tube  about  two  yards  in  length,  and  provided 
at  the  other  extremity  with  a  nozzle  with  a  stop-cock 
attachment.  At  the  end  near  the  nozzle  the  tube  passes 
through  a  flask  in  which  it  is  looped  several  times.  The 
bottle  is  placed  in  a  vessel  of  hot  water,  and  the  flask  is 
also  filled  with  hot  water  in  order  to  prevent  any  con- 
densation of  the  vaporized  ether  before  it  enters  the 
rectum.  By  means  of  the  stop-cock  it  is  possible  to 
administer  or  withhold  the  anaesthetic  at  pleasure,  with- 
out withdrawing  the  tube.  Dr.  Wanscher  has  induced 
anaesthesia  by  this  method  successfully  in  a  number  of 
cases,  especially  in  operations  about  the  head  and  neck, 
and  when  openings  were  to  be  made  into  the  thoracic 
cavity  for  the  evacuation  of  the  fluid  in  empyema. 

A  Genius  to  Fail. — Speaking  of  the  causes  of  failure 
in  life,  Tourgee  says :  "  Trying  to  carry  too  big  a  load, 
I  don't  know  about  a  professional  man's  failing  if  he 
works,  keeps  sober,  and  sleeps  at  home.  Lawyers,  minis- 
ters, and  doctors  live  on  the  sins  of  the  people,  and,  of 
course,  grow  fat  under  reasonable  exertion,  unless  com- 
petition is  too  great.  It  requires  real  genius  to  fail  in 
either  of  these  walks  of  life." 


The   Medical   Re 


^^ICAf 


A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  xo 


New  York,  September  6,  1884 


Whole  No.  722 


C^gitml  Ji^rticles. 


THE  MEDICAL  HISTORY  OF  THE  CASES  OF 
THE  SURVIVORS  OF  THE  LADY  FRANK- 
LIN BAY  EXPEDITION. 

By  EDWARD  H.  GREEN,  M.D., 

PASSBD  ASSISTANT  SURGKON  U.S.N.    . 

As  a  preliminary  to  a  medical  history  of  the  cases  of  the 
survivors  of  the  Lady  Franklin  Bay  Expedition,  it  is  well 
to  give  a  brief  r^um^  of  their  mode  of  life  at  Camp 
Clay,  their  quarters,  rations,  etc.,  so  as  to  better  ap- 
preciate the  condition  in  which  they  were  found. 

On  September  29,  1883,  Lieutenant  Greely  landed 
with  his  party  at  Baird  Inlet  after  thirty  days'  exposure, 
drifting  on  an  ice-floe  ;  the  record  left  at  that  time  stated 
tat  party  was  all  well.  Having  sent  an  advance  detach- 
ment ahead,  it  was  found  and  reported  that  a  cache  of 
provisions  existed  at  Cape  Sabine  (fifteen  miles  further 
to  the  northward  than  he  was  at  this  time).  It  was 
deemed  expedient  to  move  the  whole  command  up  to 
that  neighborhood  rather  than  send  for  the  provisions 
and  winter  at  Baird  Inlet.  Finally,  on  October  25th,  they 
moved  around  to  a  point  between  Cape  Sabine  and 
"Cocked  Hat  Island,"  lat.  78°  45'  N.,  long.  74°  15'  W. 
The  site  of  their  winter  quarters  was  sheltered  between 
hi^  ridges  of  mountains,  which  screened  them  in  a 
measure  from  the  northerly  and  southerly  winds.  A 
fjadti  was  situated  at  the  foot  of  the  mountain,  on  either 
side  of  them,  about  a  mile  distant  They  constructed  a 
house  of  loose  rocks  and  moss,  the  walls  being  3  feet  ki 
thickness.  The  roofing  consisted  of  old  canvas  stretched 
over  a  boat.  The  dimensions  of  the  house  were  25  feet 
long  by  1 7  feet  wide  by  4  feet  high,  making  the  cubic 
air  space  1,700  feet.  In  this  the  twenty-five  members  of 
the  party  Hved  all  winter,  having  a  cubic  air  allowance 
of  about  seventy  feet  for  each  man.  The  whole  party 
could  barely  squeeze  in  and  lie  at  length,  two  or  three 
being  obliged  to  occupy  the  same  sleeping-bag.  The 
effects  of  this  diminished  air  space  will  be  seen  later  on. 
Their  hut  was  but  100  yards  removed  from  the  ice-foot 
of  the  Sound,  and  200  ^ards  to  the  south  of  them  was  an 
artificial  lake,  from  which  they  drew  their  water-supply 
by  melting  up  ice.  As  the  sea-water  strained  into  this 
]ake,  they  were  drinking  brackish  water  all  the  while. 

On  November  ist  Lieutenant  Greely  took  a  careful 
account  of  his  stock  of  provisions,  and  found  there  was 
bat  a  whole  ration  for  each  man  (estimated  as  an  army 
ration,  about  forty-six  ounces  solid  food  per  diem)  for  forty 
days.    Dr.  Pavy  and  he  advised  together,  and  it  was 
with  some  reluctance  that  they  determined  to  divide  up 
the  rations  so  as  to  make  them  last  until  March  ist,  put- 
ting aside  from  time  to  time  so  that  at  the  end  they 
would  still  have  ten  days'  supplies  left  with  which  to 
attempt  the  trip  to  Littleton  Island,  if  the  Straits  were 
frozen  over.     Dr.  Pavy  did  not  think  the  party  could 
exist  on  the  ration  during  the  winter ;  but  the  common 
voice  was  to  make  it  go  as  far  as  it  would,  so  each  man 
was  given  the  following  daily  allowance :    Meat  and 
blabber,  4.33  ounces  ;  bread  and  dog-biscuit,  6.5  ounces ; 
canned  vegetables  and  rice,   1.40  ounce;   butter  and 
^ci,  a75  ounce;  soup  and  beef  extract,  0.90  ounce; 
berries,  pickles,  raisins,  and  milk,  i  ounce,  making  the 
daily  allowance  for  the  four  months  14.88  ounces.     Dur- 
ing the  winter  the  following  amount  of  game  was  secured, 


which  added  to  their  stores :  two  seals,  3rielding  about  120 
pounds  of  meat ;  one  bear,  yielding  300  pounds  of  meat ; 
eight  foxes,  4  pounds  each;  and  sixty  dovekies  (Uria 
brunnichii),  a  small  bird  weighing  about  a  pound. 

March  ist — Found  die  party  intact  with  the  exception 
of  Sergeant  Cross,  who  died  in  January  with  well-marked 
scorbutic  symptoms,  the  only  case  of  pronounced  scurv}' 
that  developed ;  and  Hans,  their  Eskimo  hunter,  who  was 
lost  in  his  boat  while  hunting  seal^  early  in  February. 
The  Straits  having  been  kept  open  during  the  winter  by  a 
succession  of  violent  gales,  the  attempt  to  cross  to  Little- 
ton Island  had  to  be  abandoned,  and  their  ration  was 
still  further  reduced  to  the  following  allowance  :  meat  6.8 
ounces ;  bread  and  dog-biscuit  3.2  ounces,  the  rest  oi  their 
stores  being  exhausted  The  stores  were  divided  up  so  as 
to  last  until  May  12th.  The  sun  had  returned  by  this  time, 
after  an  absence  of  one  hundred  and  twenty-eight  days, 
and  those  employed  as  hunters  caught  the  sea-fleas  or 
shrimp,  a  small  Crustacea^  to  ^  in.  long,  consisting  of  about 
four-fifths  shell  and  one-fifth  meat.  From  i  to  3  ounces  of 
these  a  day — according  to  the  catch — were  allowed  in  addi- 
tion to  the  ration.  After  the  last  reduction  the  party  be- 
gan to  weaken  and  die  ofl*  rapidly.  About  March  24th  the 
whole  party  was  overcome  with  asphyxia,  and  nearly  lost 
their  lives,  owing  to  the  atmosphere  being  surcharged 
with  carbonic  acid ;  they  had  lit  their  alcohol  stove  in  the 
hut  to  cook  a  meal,  without  previously  having  removed 
the  rags  from  the  vent-hole  in  the  roof.  The  remaining 
oxygen  of  the  air  was  soon  consumed  by  the  stove,  and 
the  whole  party  were  seized  with  faintness,  vertigo,  and 
dyspnoea.  It  was  with  the  greatest  difficulty  they  strug- 
gled from  their  sleepinp;-bags,  and  stumbled  and  were 
helped  into  the  open  air,  many  fainting  away  and  drop- 
ping unconsciously  after  reaching  the  open.  Being  poorly 
clad  for  a  temperature  such  as  prevailed  outside  at  the  time 
(—46**  F.),  many  were  frostbitten.  The  after-effects  of 
this  mishap  remained  for  a  long  time  and  weakened  many 
of  them.  After  May  12th  everything  like  a  regular  ra- 
tion was  exhausted,  and  they  struggled  on  as  best  they 
could,  catching  the  shrimp  (which  they  boiled)  gathering 
reindeer  moss,  which  when  boiled  yields  a  mucilage 
(similar  to  Iceland  moss),  and  boiling  up  the  seal-skin 
linings  of  the^r  sleeping-bags  (from  which  a  gelatinous 
mass  was  extracted).  It  was  not  until  they  had  exhausted 
the  supply  of  moss  around  the  camp  that  they  gathered 
the  black  lichen  (cr^pe  de  la  roche)  growing  on  the 
rocks  and  boiled  that.  Dr.  Pavy  spoke  strongly  against 
its  use,  as  he  had  the  authority  of  Kane  and  Hayes  that 
when  eaten  it  would  produce  a  diarrhoea,  which,  in  their 
weakened  condition,  would  be  fatal.  They  had  no  fuel 
for  artificial  warmth,  and  barely  sufficient  to  allow  for 
melting  the  ice  for  procuring  drinking-water,  and  to  cook 
a  meal  every  other  day,  so  that  the  living  temperature  of 
the  hut  for  the  winter  was  from  5°  to  10    F. 

They  recognized  the  fact  that  the  nearest  they  could 
approach  a  state  of  hibernation  the  better  were  their 
chances  of  getting  through.  Only  those  employed  as 
cooks  and  hunters  exerted  themselves  much,  and  they 
were  given  a  double  ration.  The  rest  of  them  occupied 
their  sleeping-bags  and  slept  sixteen  to  eighteen  hours 
out  of  the  twenty-four.  In  answer  to  complaints  of 
hunger  Dr.  Pavy's  motto  was,  "quidort  dine,"  which  was 
philosophical  without  being  filling. 

There  seemed  to  be  but  little  acute  suffering  from  the 
lack  of  food,  it  was  only  after  the  introduction  of  food 
into  the  stomach  that  the  craving  became  great ;  for 


254 


THE  MEDICAL  RECORD. 


[September  6^  1884. 


days  they  went  without  food  without  actually  suffering. 
The  deaths  seemed  to  take  place  finally  from  heart  trouble 
(hydrops  pericardii) ;  the  feet  and  face  became  oedematous ; 
for  a  day  or  so  they  would  complain  of  pains  over  the  heart, 
have  a  spasm  of  pain  over  praecordia,  a  slight  general 
convulsion,  and  all  would  be  over.  Their  chief  su£fering 
during  the  winter  was  from  constipation;  many  went 
eight  to  ten  days  without  a  stool,  and  one  as  long  as 
sixteen  days.  The  faeces  became  so  hardened  and  im- 
pacted in  the  rectum  that  at  each  operation  they  were 
obliged  to  dig  them  out  with  their  fingers,  the  abdominal 
muscles  being  too  weak  to  extrude  the  mass;  nearly 
every  one  would  faint,  after  having  a  stool,  of  sheer  ex- 
haustion. 

When  it  is  considered  that  for  nine  months  they  were 
on  the  ration  as  detailed,  had  nothing  but  brackish  water 
to  drink,  no  artificial  warmth,  living  in  a  temperature  of 
five  to  ten  degrees  for  the  winter,  with  a  cubic  air  space 
of  seventy  feet  pep  man,  the  condition  in  which  the 
survivors  were  found  will  not  be  wondered  at.  There 
were  but  seven  out  of  the  twenty-five  found  alive.  These 
were  A.  W,  Greely,  first  lieutenant,  U.S.A.;  Henry 
Beiderlick,  hospital  steward  ;  D.  L.  Brainard,  sergeant, 
U.S.A.;  Thomas  Connell,  private,  U.S.A.;  Joseph  Elli- 
son, sergeant,  U.S. A.;  Julius  Frederick,  sergeant,  U.S.A.; 
Francis  Long,  sergeant,  U.S.A.  The  four  first  men- 
tioned were  taken  on  board  the  flagship  Thetis  and 
placed  under  my  care,  and  with  them  this  paper  will 
principally  be  concerned. 

On  landing  at  the  camp,  the  condition  of  the  party 
was  so  desperate  that  a  delay  of  two  hours  was  necessary 
to  restore  them  sufficiently  to  permit  their  being  removed 
on  stretchers  to  the  boats  and  taken  off  to  the  ships. 
Thomas  Connell,  private,  was  in  extremis,  was  pulseless, 
unconscious,  and  unable  to  swallow ;  limbs  cold  and  res- 
pirations barely  noticeable.  Auscultating  over  the  heart, 
the  sounds  were  heard  very  indistinctly  by  propping  him 
up ;  forcing  open  the  jaws,  a  teaspoonful  of  brandy  was 
slowly  poured  into  the  back  of  the  throat.  The  effect  of 
the  stimulant  was  soon  noticeable,  as  a  faint  pulse  ap- 
peared at  the  wrist ;  in  ten  minutes  he  could  make  an 
effort  to  swallow,  when  more  brandy  was  adminstered, 
followed  by  some  warm  condensed  milk  at  intervals.  The 
rest  of  the  party  were  served  with  brandy,  milk,  and 
beef  essence,  and  finally  transported .  to  the  ships. 

The  time  and  space  would  hardly  be  allowed  me  to 
give  more  than  a  brief  detail  of  the  cases,  and  as  they 
closely  resembled  each  other,  both  in  symptoms  and 
treatment,  I  will  confine  myself  to  the  case  of  Lieutenant 
A.  W.  Greely  more  particularly,  alluding  to  anything 
peculiar  in  the  other  cases. 

June  2 2d,  II  P.M. — A.  W.  Greely,  lieutenant,  U.S.A., 
aged  forty.  Disease  asthenia;  on  admission  fainted 
after  being  carried  below  in  the  ward-room  and  vomited ; 
administered  ammonia  spts.  aromat.  6  cc,  renewed  in 
ten  minutes ;  placed  in  the  berth ;  given  a  teaspoonful 
of  raw,  firesh  beefi  minced  ;  clothes  were  carefully  cut  off 
of  him  and  heavy  red  flannels,  previously  warmed,  sub- 
stituted. 

On  examination  his  body  emitted  a  sickly  offensive 
odor  (as  of  stale  urine) ;  emaciated  to  a  degree.  Skin 
hanging  from  limbs  in  flaps;  face,  hands,  and  scalp 
blackened  with  thick  crust  of  soot  and  dirt  (had  not 
washed  or  changed  clothing  for  ten  months).  Nervous 
system :  excitable  and  irritable ;  at  times  almost  ir- 
rational ;  eyes  wild  and  staring ;  insists  on  talking,  crav- 
ing; news,  and  demanding  food ;  complains  of  no  pain. 
Digestive  system :  tongue  dry  and  cracked,  heavy  brown- 
ish-black coat ;  ravenously  hungry ;  abdominal  cavity 
hollow  and  lying  almost  in  contact  with  vertebral  column ; 
no  movement  of  bowels  for  six  days ;  liver  dulness ;  on 
percussion  confined  to  right  hypochondriac  region.  Res- 
piratory system  :  respirations  12  per  minute;  ausculta- 
tion and  percussion  reveal  no  abnormal  condition  of 
lungs ;  vesicular  murmur  puerile.  Circulatory  system  : 
pulse   52,    soft    or    compressible ;    auscultation    shows 


marked  murmur  (blowing)  in  systole  over  base  of  heart. 
Integumentary  system :  skin  cold  and  clammy,  sickly 
odor  emanating  from  it,  shrivelled  and  sallow ;  tempera- 
ture 97.2°  (under  tongue).  Locomotor  system :  great 
muscular  waste  ;  unable  to  move  or  stand  without  sup- 
port; body  weight  120  pounds;  weight  before  leaving 
Fort  Conger  in  August,  1883,  168  pounds.  Urinary 
system  :  no  specimen  obtainable.  Treatment :  From  n 
P.M.  till  8  A.M.,  alternated  every  half  hour,  teaspoonful 
of  raw,  fresh  beef  (minced)  with  teaspoonful  of  milk 
punch  ;  enjoined  strict  quiet ;  pulse  then  rose  to  60  per 
minute,  soft ;  temperature  97®. 

June  23d. — Nervous  system :  mind  still  active  and 
restless,  compelled  to  allow  him  some  home  letters  to 
read,  after  which  became  more  composed ;  has  not  closed 
his  eyes ;  talks  rationally,  but  shows  loss  of  memory,  as 
often  repeats  himself.  Digestive  system  :  had  a  small 
highly  offensive  stool ;  felt  quite  faint ;  afterward  passed 
considerable  wind  from  bowels;  abdomen  tympanitic; 
tongue  still  dry  and  coated.  Circulatory  system  :  pulse 
slightly  stronger,  60  per  minute;  respiration  12  per  min- 
ute. Integumentary  system :  same  offensive  odor ; 
temperature,  A.M.,  97.8° ;  p.m.,  98*^.  Locomotor  sys- 
tem :  still  unable  to  rise  up  without  help ;  muscles 
very  soft  and  flabby  ;  some  stiffness  and  pain  in  the 
joints.  Urinary  system:  urine  passed  in  twenty-four 
hours,  1,630  cc,  specific  gravity  1.014 ;  acid,  highly 
albuminous  (^^  tube).  Treatment :  Continue  raw  fresh 
beef  at  intervals  of  an  hour,  with  a  raw  onion,  finely  cut 
up,  added ;  also,  milk  punch,  half  an  ounce  every  two 
hours ;  no  medication. 

June  24th. — No  sleep  ;  mind  more  tranquil,  but  too  ac- 
tive ;  great  desire  to  talk  and  read ;  less  persistent  in 
demanding  food ;  complains  of  soreness  in  limbs ;  tODflie 
presents  a  moister  appearance  ;  bowels  slightly  distended 
with  gas ;  no  stool ;  pulse,  62°,  not  so  thready ;  heart 
sounds  stronger ;  still  a  pronounced  anaemic  murmur. 
Blood  examined  microscopically  shows  large  increase  of 
white  corpuscles;  at  first  the  field  (-^  objective)  ap- 
peared filled  with  the  nucleated  corpuscles  ;  close  exam- 
ination showed  the  proportion  to  be  about  one  to  twenty 
red  ;  the  red  corpuscles  show  but  little  disposition  to  co- 
here and  run  into  "rouleaux,"  and  lacked  the  distinctive 
biconcave  disk  shape  ;  edges  full  and  round  (not  ragged). 
Urine  passed  in  twenty-four  hours,  1,660  cc,  highly 
albuminous;  no  casts  revealed  by  microscope;  skin 
clammy,  dirty  mottled  yellow.  Temperature,  A.M., 
97.6°  ;  P.M.,  98°  ;  muscles  sore  ;  slight  oedema  of  hands 
and  ankles.  Treatment :  Sponging  with  tepid  water,  af- 
terward briskly  rubbed  with 'flannels,  and  a  little  lin. 
sapo.  Small  quantity  of  oatmeal  (thoroughly  boiled), 
four  ounces  allowed  in  morning  ;  beef  essence,  Liebig's, 
one  drachm  in  hot  water  every  foiir  hours.  Continue 
scraped  beef  and  onion  ;  no  medication. 

June  2  5 til. — Marked  improvement ;  mind  more  tran- 
quil ;  talks  quietly  without  excitement ;  slept  two  or 
three  hours  naturally,  awoke  refreshed.  Tongue  begin- 
ning to  clean ;  had  a  large  dark  semi-solid  stool ;  odor 
offensive  in  the  extreme,  evidently  but  little  biliary  se- 
cretion poured  into  alimentary  canal  Pulse,  65°  ;  sodeic 
strength ;  respiration,  14°,  principally  costal ;  skin  losing 
clammy  feel ;  emanation  still  sour  and  offensive  from  it 
Temperature,  a.m.,  98.2°  ;  p.m.,  98'' ;  muscles  sore,  ankles 
puffed.  Treatment :  Shampooing  muscles  with  dry 
cloths ;  no  change  in  diet ;  no  medication. 

June  26th. — Allowed  to  sit  up  in  bed  and  read  a  little; 
slept  six  hours  soundly  during  the  night ;  mind  tranquil ; 
has  a  loss  of  memory  of  words ;  tongue  cleaning,  still  a 
heavy  coat  at  the  back;  bowels  moved  twice;  stools 
pitchy  and  offensive  ;  abdomen  tympanitic,  considerable 
borborygmus ;  pulse,  65  ;  heart  sounds  stronger ;  mur- 
murs still  pronounced ;  urine  passed  in  twenty-four  hours, 
1,800  cc  ;  specific  gravity,  ioi6;  albumen  not  de- 
creased ;  no  change  in  condition  of  skin.  Temperature, 
A.M.,  98°  ;  P.M.,  98.8°.  Treatment:  Sponging  and  fric- 
tion.    Same  dietary  with  tr.  ferri  muriat.,  5  cc  L  i.  d. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


255 


June  27th. — Still  extremely  weak;  voice  stronger; 
mind  easier;  amnesic  aphasia  marked;  appetite  still 
morbid,  always  hungry ;  considerable  flatulency ;  no 
stool;  aspect  of  skin  somewhat  improved  in  appear- 
ance ;  still  dirty  yellow  (in  spots).  Temperature,  a«m., 
98.4'* ;  P.M.,  98.8° ;  pulse,  66 ;  respiration,  14 ;  urine  albu- 
minous (^tube),  1,950  cc  in  twenty-four  hours ;  specific 
gravity,  1.018;  muscles  beginning  to  fill  out;  very  soft. 
Treatment :  Dietary  increased  to  eight  ounces  broiled 
steak  in  morning  ;  continued  ferri  muriat. 

June  28th. — Gaining  strength ;  dressed  and  sat  up  for 
a  couple  of  hours,  then  felt  exhausted  and  returned  to 
bed;  mind  quite  tranquil;  slept  well;  appetite  still  mor- 
bid; bowels  moved;  no  change*  in  character  of  stool ; 
liver  still  inactive.  Pulse,  66 ;  feirly  good  tone.  Anaemic 
murmur  not  so  marked.  Temperature,  a.m.,  98.2^ ; 
P.M.,  98°.  Urine  passed  in  twenty-four  hours,  1,860  c.c; 
specific  gravity,  i.oz8;  albumen  present.  Treatment: 
Takes  food  at  five  stated  intervals :  6  a.m.,  oatmeal, 
4  ounces,  broiled  steak,  8  ounces ;  10  a.m.,  Liebig's 
beef  essence,  i  drachm  in  teacup  of  warm  water;  2  p.m., 
one  soft-boiled  egg  with  milk  toast ;  6  p.m.,  raw  minced 
beef  and  onion  ;  10  p.m.,  Liebig's  essence  of  beef.  Con- 
tinue tr.  ferri  muriat.,  6  cc,  t.  i.  d. 

June  29th. — Dressed  and  assisted  to  walk  in  ward-room 
a  few  steps  ;  muscles  soft ;  very  weak  ;  limbs  filling  out ; 
body  weight,  129^  pounds  (gain  of  9^  pounds  for  the 
week).  Pulse,  68.  Urine,  1.650  c.c.  in  twenty-four  hours ; 
albumen  less.  Temperature,  a.m.  and  p.m.,  normal. 
Bowels  moved  naturally ;  stool  still  pitchy  and  offensive. 
Treatment :  Continue  the  same. 

June  30th. — Sleeps  naturally  and  awakes  refireshed; 
allowed  to  read  and  talk ;  walks  around  for  an  hour  or 
so  with  support;  limbs  filling  out;  feet  oedematous 
toward  night.  Appetite  still  morbid,  unable  to  be  satis- 
fied with  his  allowance ;  good  movement  of  bowels ;  al- 
bumen disappearing ;  heart  sounds  stronger.  Tempera- 
ture normaL     Continue  restricted  diet  and  iron. 

July  ist. — Felt  quite  refreshed  on  awaking ;  had  slept 
well  during  the  night ;  enjoyed  morning  meal,  and  ate 
without  asking  for  more.  As  the  sun  was  shining  brightly, 
was  assisted  on  deck  and  sat  in  the  air  (well  bundled  up) 
for  an  hour.  Had  but  little  appetite  for  mid-day  meal. 
At  4  p.m.  a  small,  dark,  offensive  stool)  strained  consider- 
ably and  was  much  exhausted  afterward  (nearly  fainted)  ; 
administered  spts.  frumenti,  |  ss.  in  aqua.  At  6  p.m.  com- 
plained of  severe  pains  in  abdominal  muscles  and  over 
the  region  of  the  liver  (pains  resembling  hepatic  colic) ; 
considerable  febrile  disturbance.  Pulse,  98.  Temperature, 
100. 2^     Administered  quin.  sulph.,  3  cc,  at  8  p.m. 

July  2d. — Feels  much  prostrated  and  weak ;  muscular 
pains  and  soreness  over  abdomen  and  back.  Complexion 
sallow;  appetite  poor.  Temperature,  8  a.m.,  98.8^;  12 
M.,  99°;  4  p.  M.,  99.2°.  Exhibited  hydrarg.  chlorid.  nit, 
3  c.c.  at  8  A.M.,  repeated  dose  at  2  p.  m.  Bowels  moved 
three  times,  last  evacuation  watery.  Felt  weak,  but  free 
of  cramps ;  headache  disappeared.  Light  diet  of  oatmeal 
and  milk.     Discontinued  tr.  ferri  muriat. 

July  3d. — Still  weak ;  muscular  soreness  over  abdo- 
men; no  sharp  pains;  two  loose  evacuations  from 
bowels.  Appetite  returning.  Pulse,  6S,  Temperature 
normal.     Whiskey  toddy,  |  ss.  1. 1  d. 

July  4th. — Considerable  improvement ;  pains  have  dis- 
appeared from  muscles,  tongue  cleaner,  complexion  bet- 
ter. Allowed  to  sit  up  to  his  meals.  Urine  much  improved ; 
albumen  (^  tube)  ;  specific  gravity  1.022.  Resume  tr. 
ferri  muriat,  also  vin.  Portense,  |  j.,  t.  i.  d.  before  meals. 

July  5th. — Gaining  strength  gradually  ;  muscles  soft ; 
knees  weak;  encouraged  to  take  some  exercise  daily, 
weather  permitting,  in  the  open  air.  Digestion  good ;  ap- 
petite under  better  control;  liver  still  torpid;  regular 
movement  of  bowels ;  skin  clearing,  lost  clamminess ; 
sleeps  well  Continue  same.  From  this  time  forth 
gradual  improvement.  Blood  again  examined  micro- 
scopically shows  marked  diminution  of  white  corpuscles. 
On  July  8th,  no  albumen  found  in  urine.     On  July 


1 2th,  anaemic  murmur  very  indistinct  On  July  17th  ar- 
rived at  St  Johns.  Condition  sufficiently  improved  to 
warrant  his  going  ashore  for  exercise  ;  muscles  still  weak 
and  sore  ;  filled  out  rapidly. 

July  19th. — Had  a  slight  attack  of  intestinal  indigestion; 
was  living  ashore  at  the  consul's  and  committed  an  error 
in  diet ;  suffered  for  two  days. 

July  25  th. — Allowed  to  eat  three  fiill  meals  daily,  with 
certain  articles  restricted ;  encouraged  to  exercise  in 
open  air.  On  the  trip  from  St  Johns  to  Portsmouth, 
N.  H.  (July  26th  to  August  xst),  ran  into  damp,  moist 
weather ;  felt  much  prostrated,  and  muscles  ached.  Given 
quin.  sulph.,  18  c.c,  every  night  during  the  run.  On  being 
transferred  at  Portsmouth,  his  body  weight  was  169  pounds, 
representing  a  gain  of  49  pounds  in  six  weeks— 9^  pounds 
first  weeky.15  pounds  second  week,  8  pounds  third  week, 
7  pounds  fourth  week,  5^  pounds  fifth  week,  4  pounds 
sixth  week. 

Remarks, — Vital  depression,  as  exhibited  by  the  tem- 
perature, not  marked ;  digestion  fairly  good  all  the  time  ; 
nervous  system  soon  calmed.  Microscopic  examination 
of  blood  disappointing  ;  exhibiting  no  unhealthy  charac- 
terjof  red  blood-globules.  Albumen  disappearing.  Anae- 
mic murmur  disappearing,  showing  it  to  be  simply  due  to 
hydraemic  condition  of  blood ;  liver  not  secreting.  Large 
gain  in  weight,  due  to  rapid  assimilation  of  food,  owing 
to  a  great  muscular  waste.  Large  urinary  excretion 
(1,950  C.C.  in  one  day),  due  doubtless  to  almost  total  in- 
activity of  sudorific  glands. 


TREATMENT  OF  CHOLERA  IN  INDIA. 
By  H.  MARTYN  SCUDDER,  M.D., 

LATB  MEDICAL  MISftlONAKY  OF  THB  AMSIUCAN   AKCOT  MISSION,   INDIA, 
CHICAGO,   ILL. 

For  purposes  of  treatment  I  would  divide  the  course  of 
this  disease  into  the  following  stages :  A  period  of  pro- 
dromes or  prodromic  stage ;  a  first  stage,  or  state  of 
diarrhoea  or  chlorine ;  a  second  stage,  or  stage  of  inva- 
sion ;  a  third  stage,  or  stage  of  collapse  (algid  stage) ;  a 
fourth  stage,  or  stage  of  reaction.  This  last  sta^e  of  re- 
action may  be  succeeded  by  a  typhoid  condition,  or 
cholera  typhoid  stage,  or  else  may  pass  directly  into  a 
state  of  convalescence.  In  the  prodromic  stage,  mani- 
fested by  lassitude,  mental  depression,  chilliness,  nausea, 
and  abdominal  discomfort,  give  ten  or  fifteen  drops  of 
spirits  of  camphor  in  dessert-spoonfuls  of  hot  brandy 
every  hour  or  two,  but  be  careful  not  to  allow  any  con- 
siderable quantity  of  stimulants  to  be  taken.  When 
epidemic  cholera  is  prevalent  many  are  afifected  by  the 
sjrmptoms  just  described.  If  the  remedies  I  have  indi- 
cated are  promptly  taken,  I  feel  confident  many  attacks 
of  cholera  will  be  warded  off.  It  is  true  that  fear  of- 
ten produces  these  very  symptoms,  but  the  spirits  of 
camphor  in  spoonfuls  of  warm  brandy  tends  to  soothe 
the  fears  and  dissipate  these  symptoms,  and  yet  does  not 
usually  disorder  the  digestion. 

As  soon  as  diarrhoea  begins,  the  administration  of  some 
preparation  of  opium  together  with  aromatics,  camphor, 
and  a  little  chloroform,  is  urgently  called  for.  Two  parts 
of  "  chlorodyne  "  to  one  of  spirits  of  camphor  is  a  very 
good  combination,  thirty  drops  for  a  dose.  To  be  re- 
peated as  required.  Another  very  serviceable  prescrip- 
tion consists  of  equal  parts  of  spirits  of  chloroform,  spirits 
of  camphor,  laudanum,  aromatic  tincture  of  rhubarb,  and 
tincture  of  ginger.  Teaspoonful  doses  every  hour  or 
two  according  to  the  urgency  of  the  case  until  four  or 
five  doses  have  been  taken.  In  alternation  with  either 
of  the  combinations,  an  aromatic  sulphuric  acid  mixture 
may  be  given  to  advantage.  A  popular  formula  is  as 
follows  : 

9.   Acid,  sulphuric,  aromat.. .    |j. 

Tinct.  opii  deodorat 3  vj.  vel  f  j. 

M.    Sig. — Twenty  or  thirty  drops   in  water  every 
hour  or  two. 

I   think  it  important   to  administer   these   remedies 


256 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


hot,  unless  they  create  nausea.  The  hot  water,  or  mor- 
phine combined  with  chloral,  should  be  administered  by 
hypodermic  injection,  as  the  severity  of  the  case  may 
demand.  Either  of  the  following  formulas  may  be  chosen 
for  exhibition  every  half  hour  or  hour  just  after  a  spell 
of  vomiting  : 

Q.   Chloroform., 

Tinct.  capsici, 

Tinct.  cannab.  ind aa  VI  xxx. 

Acid,  hydrocyanic,  dil TTi  xx. 

Ether TT[  viij. 

Spts.  menthae  pip TTi  xv. 

Syrup  sassafras  comp ad  §  j. 

Sig. — A  small  teaspoonful  every  half  hour  or  hour. 

9.    Spts.  ammonia  aromatic, 

Spts.  of  chloroform fi&    |  j. 

Tinct  of  capsicum, 

Compound  tinct.  of  cardamom, 

Tinct.  of  ginger aa    |  ss. 

M.     Give  in  the  same  doses  as  the  above. 

A  mixture  of  aromatic  powder,  gum  arabic,  and  ace- 
tate of  lead  may  also  be  given  alternately  with  either  of 
these,  if  desired.  In  any  case  a  mustard  plaster  should 
be  applied  over  the  stomach  and  abdomen,  but  not  left 
on  too  long ;  and,  if  required,  enemata  of  eight  or  ten 
grains  of  acetate  of  lead  may  be  given  after  each  evacua^ 
tion.  I  think  it  is  important  to  bear  in  mind  that  some 
preparation  of  opium  or  morphine,  or  morphia  combined 
with  chloral,  is  the  chief  remedy  for  cholera,  and  the 
surest  agent  we  can  use  to  arrest  the  progress  of  the  dis- 
ease. When  called,  therefore,  to  a  case  abready  in  the 
stage  of  invasion,  I  believe  morphine,  or  morphine  and 
chloral,  should  be  administered  hypodermatically  without 
delay,  in  order  to  get  these  sovereign  remedies  into  the 
system  as  soon  as  possible  ;  for  if  we  can  arrest  the  dis- 
ease before  the  patient  beeomes  collapsed,  his  chances 
of  recovery  will  be  very  greatly  increased.  Caution  must 
be  exercised,  however,  when  this  form  of  treatment  is 
pursued,  for  narcotism  is  easily  induced  by  repeated 
hypodermic  injections,  whereas  very  large  doses  of  opi- 
ates can  be  given  in  this  disease,  by  mouth  and  rectum, 
with  comparative  impunity.  The  strength  of  the  solu- 
tion usually  employed  for  injection  is  morphine,  gr.  iijss. 
or  gr.  iv.,  with  chloral  hyd.,  3  ijss.  or  3  iij.  to  the  ounce 
of  water.     Inject  twenty  or  thirty  minims. 

The  hypodermic  use  of  morphine  and  chloral  is,  of 
course,  contraindicated  when  the  stage  of  collapse  has 
become  well  developed.  During  this  stage  it  is  most 
essential  that  the  patient  should  be  kept  perfectly  quiet, 
and  in  the  horizontal  position.  No  violent  rubbing 
should  be  allowed,  but  I  have  found  it  beneficial  to 
gently  rub  the  limbs  and  extremities  with  hot  oil.  To 
allay  thirst  let  the  patient  suck  ice  frequently.  Carbolic 
acid  water  or  simple  acidulated  effervescing  drinks  may 
also  be  given  by  the  tablespoonfuL  It  is  unsafe  to 
allow  the  patient  to  drink  any  fluid  whatsoever  in  large 
quantities.  In  this  stage,  especially  when  the  acts  of 
vomiting  and  purging  have  become  less  frequent  and  the 
algid  state  well  developed,  very  small  quantities  of  stimu- 
lants are  useful,  but  they  should  be  given  with  great 
caution,  lest  vomiting  should  be  provoked.  Stimulating 
enemata  may  also  be  given,  but  where  the  stomach  is 
intolerant  it  is  often  better  to  inject  small  quantities 
hypodermatically.  Experience  teaches  us,  however,  that 
anything  like  the  free  use  of  stimulants  in  cholera  is  un- 
called for  and  exceedingly  harmful.  I  have  sometimes 
found  small  doses  of  both  atropia  and  strychnia,  adminis- 
tered by  hypodermic  injection,  apparently  effectual  in 
brining  about  reaction.  Amyl  nitrite,  by  inhalation,  may 
be  given,  but  it  seems  to  exercise  very  little  permanent 
beneficial  effect.  Intravenous  administration  of  milk 
and  salines  may  be  resorted  to,  but  the  reaction  thus 
produced  is  not  generally  of  a  permanent  character,  so 
that  many  of  those  who  have  given  this  method  a  fair 
trial  have  abandoned  it. 


Of  late  years,  in  Southern  India,  careful  experiments 
have  been  carried  out  in  reference  to  the  value  of  im- 
pregnating  the  atmosphere  of  the  sick  room  with  sul- 
phurous acid,  by  the  burning  of  sulphur.  The  result 
has  been  that  this  procedure  has  been  introduced  as  part 
of  the  treatment  of  cholera.  I  have  on  several  oc- 
casions carefully  tried  this  plan  myself,  by  subjecting 
the  inmates  of  two  different  cholera  sheds  to  exactly  the 
same  conditions  and  treatment  in  every  respect,  with  the 
exception  that  in  one  the  atmosphere  of  the  shed  was 
kept  impregnated  with  sulphurous  acid,  and  in  the  other 
no^,  I  have  always  found  that  the  proportion  of  recov- 
eries was  considerably  greater  in  the  shed  where  sul- 
phur was  burned.  I  therefore  now  always  proceed  to 
burn  sulphur  in  the  patient's  room,  as  part  of  the  treat- 
ment of  cholera,  and  consider  it  an  important  adjuvant 

The  atmosphere  should  not  be  so  highly  impregnated 
as  to  cause  the  patient  or  attendants  to  cough  violently. 

Sulphurous  acid  thus  applied  is  not  only  a  useful 
remedy,  but  it  is  also  believed  to  decrease  the  liability 
to  the  propagation  of  the  disease,  and  to  its  contraction 
by  the  attendant 

During  the  stage  of  reaction,  great  care  should  be  ex. 
ercised.  Vomiting  often  continues,  and  the  nomial  ab- 
sorbing power  of  tibe  stomach  and  intestines  is  but  slowly 
restored.  Liquid  noiirishment  by  the  spoonful  should 
be  most  cautiously  given;  well  salted  broth  and  milk, 
given  as  hot  as  possible,  and  not  too  frequently,  are  the 
only  forms  of  food  admissible  until  the  enfeebled  stom- 
ach shows  signs  of  recovering  its  tone.  Peptonized  beef- 
tea  and  milk  are  frequently  well  borne,  if  carefully  pre- 
pared (two  or  three  tablespoonfuls)  Each  dose  maybe 
sweetened,  if  desired.  The  patient  should  be  made  to 
lie  down,  kept  perfectly  quiet,  covered  with  heated 
blankets,  and  dry  heat  applied  to  the  surface  of  the  body, 
especially  to  the  extremities,  by  means  of  hot  bottles, 
heated  flat-irons,  etc.  In  India  the  administration  of 
calomel  to  any  extent  has  lately  been  discouraged,  one 
or  two  small  doses  may  be  given  if  thought  best,  but  not 
more.  As  soon  as  frequent  vomiting  commences— or  the 
stage  of  invasion  becomes  established,  the  combinations 
containing  opium  which  have  been  mentioned,  had  better 
be  discontinued,  and  either  of  the  following  mixtures 
given  in  teaspoonful  doses  at  intervals,  after  a  spell  of 
vomiting. 

At  the  same  time,  also,  morphine,  so  as  not  to  nause- 
ate the  patient.  If  vomiting  persists,  the  following  emul- 
sion may  be  given,  if  deemed  best : 

ft.  Acid,  carbolic gr.  vij. 

Bismuth,  subnit 3  ij. 

Mucil.  acaciae. 

Aqua  menth.  virid a*  §  j- 

Sig. — ^A  teaspoonful  every  hour  or  two. 

But  in  this  stage  it  is  good  treatment  to  let  nature  do 
the  work  of  restoration,  and  give  as  little  medicine  as 
possible.  We  must  have  in  mind,  however,  that  the  kid- 
neys must  be  assisted  to  resume  their  functions,  and  for 
this  purpose  mild  diuretics,  such  as  potass,  nitras,  should 
be  carefully  administered.  If  fever  supervenes,  it  is  apt 
to  be  of  a  typhoid  character :  a  combination  of  iodine  and 
carbolic  acid  then  exerts  a  beneficial  effect.  A  popular 
formula  is  as  follows  : 

ft.  Acid,  carbolic gr.  iijss. 

Tinct  iodi gtt.  xv. 

Aquas  menth.  pip f  iv. 

M.     Sig. — A  tablespoonful  every  two  or  three  hours. 

To  relieve  restlessness  and  insomnia,  potass,  bromid  is  ' 
often  useful 

If  the  attack  of  cholera  is  arrested  before  the  patient  , 
becomes  collapsed,  the  state  of  convalescence  will  prob- 
ably be  of  short  duration,  and  the  health  soon  be  re-  ; 
stored.     If,  however,  the  patient  is  rescued  after  being  . 
in  a  profound  state  of  collapse  for  a  length  of  time,  the 
convalescence  will  generally  be  protracted. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


257 


LARGE  DOSES  OF  POTASSIUM  OR  SODIUM 
IODIDE  IN  SUDDEN  DEAFNESS  OF  SUP- 
POSED SYPHILITIC  ORIGIN.' 

By  albert  H.  BUCK,  M.D., 

NBW  YORK. 

The  following  very  brief  histories  of  cases  are  offered  as 
a  contribution  to  the  subject  of  the  daily  administration — 
through  a  period  of  several  days,  or  even  weeks— of  large 
doses  of  potassium  or  sodium  iodide  for  the  relief  of  sud- 
den or  rapidly  developed  deafness  due  apparently  to  the 
presence  of  syphilitic  lesions  in  the  labyrinth,  or  in  some 
part  of  the  auditory  nerve  outside  of  this  system  of  cav- 
ities, or  finally,  in  those  parts  of  the  tympanum  which 
constitute  the  movable  barriers  of  separation  between 
this  cavity  and  those  of  the  labyrinth.  I  will  add  that  I 
have  been  careful  not  to  introduce  among  these  cases 
any  in  which  easil)r  recognizable  inflammatory  lesions, 
presumably  of  syphilitic  nature,  were  observed  in  the 
tjrmpanum,  or  any  in  which,  from  the  past  history,  it 
seemed  probable  that  any  such  middle-ear  lesions  had 
been  present  at  the  time  when  the  deafness  developed. 
I  have  omitted  such  cases  because  nobody  is  disposed  to 
doubt  the  curability  of  even  very  marked  deafness  when 
due  to  syphilitic  lesions  involving  a  large  part  of  the 
tympanic  mucous  membrane,  and  interfering  with  the 
mechanism  of  the  ossicles.'  It  would,  tlierefore  not  be 
Teiy  profitable  on  the  present  occasion  to  report  any  such 
cases;  particularly  as  my  chief  object  in  making  this 
communication  is  to  throw  a  little  light,  if  I  can,  upon 
the  prognosis  and  treatment  of  what  appears  to  be  syphi- 
litic disease  of  the  labyrinth,  and  at  the  same  time  to 
profit  by  the  experience  which  other  members  of  the  So- 
ciety may  have  had  in  the  treatment  of  such  cases,  and 
which  this  communication,  I  trust,  will  lead  them  to  pub- 
lish. On  the  other  hand,  I  have  not  thought  it  necessary 
to  exclude  one  or  two  cases  in  which  evidences  of  long- 
standing chronic  catarrhal  inflammation  of  the  tympanum 
existed,  but  in  which,  at  the  time  of  my  exammation  of 
the  ear,  no  signs  of  congestion  or  swelHng  could  be  dis- 
covered. The  profoundness  of  the  de^ness  and  the 
rapid  manner  in  which  it  developed  in  these  cases,  are, 
it  seems  to  me,  characteristics  of  syphilitic  disease  of  the 
auditory  nerve  rather  than  of  catarrhal  lesions  in  the 
tympanum. 

There  is  still  another  point  to*  which  I  must  call  atten- 
tion. In  the  majority  of  the  instances  enumerated  be- 
low, the  grounds  for  suspecting  syphilis  to  be  the  cause  of 
the  deafness  seemed  to  be  amply  sufficient,  but  in  a  few 
the  evidence  in  favor  of  such  a  conjectural  diagnosis  was 
certainly  not  strong.  Indeed,  in  one  case  (Case  IV.),  there 
TO  no  direct  evidence  that  the  patient  had  ever  had  this 
disease.  His  remarkable  tolerance  of  the  iodide  of  po- 
tassium (slowly  increasing  doses  until  finally  360  grains 
were  taken  daily  for  a  period  of  one  week)  and  the  general 
resemblance  of  his  attack  to  those  of  an  acknowledged 
syphilitic  nature,  are  the  only  grounds  on  which  I  can 
justify  myself  in  placing  this  case  in  the  same  category 
with  the  others. 

The  literature  of  this  particular  subject  is  scanty.  The 
attention  of  the  profession  was  first  called  to  it  in  1877 
by  Dr.  Roosa's  report  of  a  remarkable  case  in  which, 
from  a  condition  of  almost  total  deafness,  the  patient's 
hearing  within  a  few  weeks  was  restored  to  nearly  a  nor- 
fual  condition.'  A  second,  less  striking  instance,  is  re- 
ported by  Dr.  Roosa  on  page  526  of  the  same  work. 
Beside  these  I  can  find  only  two  other  reports  which 
throw  light  upon  the  employment  of  large  doses  of  po- 
tassium iodide  in  the  treatment  of  labyrinthine  deafness, 
presumably  of  syphilitic  origin,  viz.,  those  of  Dr.  Samuel 
Sexton*  and  Dr.   David  Webster.*     In  some  of  these 


^  A  paper  read  bdbre  the  American  Otological  Society,  July  15,  1884. 
'  S«e  the  Pathology  and  Treatment  of  Venereal  Diseases,  by  Freeman  T. 
and  and  Robert  W.Taylor.    Philadelphia:   H.C.Lea.    i«79. 
'  Roon :  Diseases  of  the  Ear,  fourth  edition,  p.  538. 
« American  Journal  of  Otoloj^,  toI.  iL,  p.  30X. 
*  Aichivcs  01  Otology,  voL  xii. 


Bum- 


cases,  however,  it  is  not  perfectly  clear  that  middle-ear 
lesions  may  not  have  contributed  materially  to  the  deaf- 
ness. 

From  the  strict  standpoint  of  scientific  inquiry  it  may 
be  objected  that  no  trustworthy  deductions  can  be  made 
from  these  published  cases,  or  from  those  which  I  am 
about  to  report,  with  regard  to  the  effects  of  the  iodides 
upon  syphilitic  labyrinthine  lesions,  inasmuch  as  in  all 
of  them,  with  a  single  exception,  mercury  was  adminis- 
tered at  the  same  time.  The  objection  is  certainly  a 
valid  one;  but,  as  an  offset,  I  will  say  that,  so  far  as 
1  have  any  knowledge  of  the  subject,  no  reports  of  suc- 
cess in  the  treatment  of  this  class  of  cases  have  ever 
been  published  previousl}^  to  1877  (Dr.  Roosa' s  report), 
that  is,  not  until  after  the  iodides  had  been  administered 
in  much  larger  doses  than  it  had  previously  been  cus- 
tomary to  administer.  From  this  circumstance,  and 
from  analogous  experiences  ^on  the  part  of  others)  in  the 
treatment  of  s^hilitic  brain  lesions,  I  think  that  we  may 
properly  ascribe  to  the  iodides  whatever  curative  phe- 
nomena have  been  observed  in  these  few  cases  of  sudden 
deafness. 

Case  I. — Male ;  thirty-eight  years  of  age ;  first  seen 
on  October  25,  1880.  He  be^an  to  grow  deaf  about 
one  year  previously.  Convulsions  occurred  at  the  on- 
set. He  was  put  at  this  time  under  ordinary  anti-syphi- 
litic treatment.  Despite  this,  however,  the  hearing  stead- 
ily and  markedly  diminished.  Patient  was  very  deaf  at 
time  of  examination,  which  revealed  no  lesions  adequate 
to  explain  the  deafness.  All  that  I  know  about  the  sub- 
sequent history  of  the  case  is  comprised  in  the  following 
extract  from  a  letter  written  by  the  physician  in  attend- 
ance, Dr.  C.  McBumey  :  "  Not  very  long  after  you  saw 
the  patient  he  developed  mania,  became  very  violent, 
and  gave  an  immense  amount  of  trouble  in  every  way. 
This  mania  was  doubtless  dependent  on  some  syphilitic 
lesion,  and  under  the  very  large  doses  of  iodide  (several 
hundred  grains  daily)  the  mental  disturbance  disap- 
peared. The  deafness,  however,  was  only  slightly  re- 
Ueved." 

Case  II. — Male ;  twenty-seven  years  of  age ;  patient 
seen  for  the  first  time  on  November  12,  1881.  He  gave 
a  history  of  decided  naso-pharyngeal  catarrh  and  slowly 
increasing  deafness  since  the  age  of  fifteen.  Eight  or 
nine  months  ago  syphilitic  manifestations.  Ten  or 
twelve  weeks  later  the  deafness,  which  up  to  that  time 
had  not  been  very  noticeable,  became  very  marked,  and 
at  the  time  of  my  first  examination  it  was  so  decided  that  I 
could  make  myself  understood  only  by  placing  my  lips 
close  to  the  patient's  right  ear  and  fairly  shouting  into  it 
what  I  had  to  say.  In  the  left  ear  the  deafness  was  ap- 
parently absolute.  In  the  right  ear  there  were  evidences 
of  a  former,  but  now  healed,  otitis  media  purulenta  (viz., 
a  cicatricial  reproduction  of  a  part  of  the  membrana 
tympani) ;  in  the  left  ear  the  membrana  tympani  was 
simply  opaque  in  appearance  and  somewhat  sunken. 
There  was  decided  naso-pharyngeal  catarrh,  with  the 
characteristic  tone  of  voice.  Eustachian  tubes  pervious 
to  air.  Hearing  not  affected  by  inflations.  It  not  be- 
in^  clear  to  what  extent  the  recent  increase  of  deafness 
might  be  due  to  the  naso-pharyngeal  catarrh,  I  directed 
treatment  toward  the  relief  of  this  affection  as  well  as 
toward  the  constitutional  syphilis.  On  the  one  hand,  I 
applied  a  solution  of  nitrate  of  silver  (twenty  grains  to  the 
ounce)  to  the  affected  mucous  membrane  of  the  naso- 
pharynx three  times  a  week ;  and  for  the  anti-syphilitic 
part  of  the  treatment  I  recommended  daily  inunctions  of 
a  five  per  cent,  preparation  of  Squibb's  oleate  of  mer- 
cury, and  the  internal  administration  of  the  iodide  of  po- 
tassium, three  times  daily,  in  increasing  doses. 

On  December  8th  the  patient's  gums  began  to  be 
noticeably  affected,  and  the  inunctions  were  accordingly 
discontinued. 

On  December  17th  he  began  to  complain  of  great 
lassitude.  He  was  then  taking  daily  only  thirty  grains  of 
the  iodide  of  potassium  and  three  grains  of  the  sesqui- 


258 


THE  MEDICAL   RECORD. 


[September  6,  1884, 


carbonate  of  ammonia.     As  his  face  also  wore  a  haggard 
look,  I  advised  him  to  stop  all  treatment  for  a  few  days. 

On  December  27th  the  iodide  of  potassium  treatment 
was  resumed ;  the  sesquicarbonate  of  ammonia  being 
omitted  from  the  mixture.  Numerous  small  ulcers  visible 
on  the  gums. 

December  30th. — Forty-five  grains  of  the  iodide  of 
potassium  daily.  The  local  applications  to  the  vault  of 
the  pharynx  were  discontinued  about  this  time. 

January  4,  1882. — Fifty-five  grains  daily.  An  eruption 
of  small  pustules  has  broken  out  on  his  face  and  shoulders. 

January  loth. — Complains  of  a  "cold  in  the  head." 

January  13th. — Sixty-five  grains  daily.  I^e  complains 
of  headache,  a  sensation  of  soreness  in  the  back,  sore 
throat,  a  very  free  discharge  from  the  nose,  frequent 
sneezing,  and  an  occasional  attack  of  coughing.  A  brief 
suspension  of  the  treatment  advised. 

January  14th. — ^Two  decided  chills  with  marked  pros- 
tration occurred  during  the  night.  This  morning  he  looks 
pale  and  haggard,  and  complains  of  a  sense  of  discomfort 
in  the  abdominal  region.  I  prescribed  a  mixture  of  the 
ammonio-citrate  of  iron  and  the  compound  tincture  of 
cinchona,  each  dose  containing  two  grains  of  the  former 
and  one  drachm  of  the  latter. 

January  17th. — The  iron  and  cinchona  mixture  soon 
produced  a  decided  ringing  in  his  ears,  and  he  discon- 
tinued it.  All  the  other  unpleasant  symptoms,  however, 
have  disappeared,  and  he  feels  comparatively  well  again. 
The  hearing,  too,  of  late,  has  noticeably  improved.  At 
times  he  has  been  able  to  understand  sentences  spoken 
in  an  ordinary  tone  of  voice  at  a  distance  of  four  or  five 
feet  from  his  right  ear.  The  improvement,  however,  has 
never  lasted  longer  than  a  few  hours,  or  at  most  a  day, 
at  a  time.  To-day  I  am  able,  sitting  directly  in  front  of 
him,  at  a  distance  of  firom  two  to  three  feet,  to  make  my- 
self understood  by  simply  raising  m^  voice  slightly.  He 
does  not  appear  to  read  my  lips ;  m  fact  they  are  con- 
cealed by  my  mustache. 

January  i8th. — At  the  suggestion  of  Dr.  F.  R.  Sturgis, 
of  this  ci^,  who  saw  the  case  in  consultation  with  me,  I 
prescribed  a  saturated  solution  of  the  iodide  of  potassium 
(i  minim,  =  about  i  grain).  Of  this  solution  the  patient 
was  instructed  to  take  fifteen  minims  three  times  a  day, 
after  his  meals,  and  afterward  to  increase  the  dose  on  the 
alternate  days  by  five  minims.  Thus,  for  example,  it  was 
intended  that  he  should  take  45  minims  a  day  on  Janu- 
ary 19th  and  20th,  60  minims  on  the  21st  and  2  2d,  75 
minims  on  the  23d  and  24th,  and  so  on. 

January  31st — He  is  now  taking  120  minims  daily 
without  any  discomfort  whatever.  Appetite  good.  A  few 
insignificant  pimples  are  still  visible  on  his  face.  During 
the  coming  week  he  is  to  discontinue  the  iodide  of  potas- 
sium, and  in  its  stead  to  take  daily  a  drachm  and  a  half 
of  the  syrup  of  the  iodide  of  iron. 

February  6th, — Potassium  iodide  resumed  :  120  minims 
daily. 

February  i8th. — One  hundred  and  ninety-five  minims 
daily.  The  papular  eruption  on  the  patient's  face  is  now 
quite  noticeable.  He  is  again  to  discontinue  the  remedy 
for  one  week,  and  to  take  the  iodide  of  iron  instead. 
A  still  further  improvement  has  taken  place  in  the  hear- 
ing. I  can  now  converse  with  him  at  a  distance  of  at 
least  four  or  five  feet ;  my  pitch  of  voice  being  as  nearly 
as  possible  the  same  as  when  I  tested  the  hearing  on 
January  17th. 

February  24th. — One  hundred  and  ninety-five  minims 
daily. 

March  3d. — ^Two  hundred  and  forty  minims  daily.  No 
discomfort  whatever  from  the  remedy.  Hearing  distance 
has  increased  to  seven  feet.  Iodide  of  iron  substituted 
for  a  few  days. 

March  8th. — Two  hundred  and  forty  minims. 

March  12th. — ^Two  hundred  and  seventy  minims. 

March  13th. — Patient  is  totally  deaf  this  morning,  the 
result,  apparently,  of  a  cold  which  he  contracted  last 
evening.   Marked  hoarseness.   Right  Fustachian  tube  ob- 


structed, and  right  membrana  tympani  markedly  sunken. 
Inflations  by  Politzer's  method  and  naso-pharyngeal  treat- 
ment to  be  resumed.  The  iodide  of  potassium  to  be  dis- 
continued. 

March  20th. — ^The  hearing  is  again  as  good  as  it  was 
on  March  3d.  Two  hundred  and  seventy  minims  to  be 
taken  to-day. 

March  24th. — ^Three  hundred  minims. 

April  28th. — Three  hundred  and  fort}'-five  minims. 

May  15th. — ^Four  hundred  and  eighty  minims. 

May  2  2d. — Five  hundred  and  twenty-five  minims. 

May  24th. — General  malaise.  Hearing  again  quite 
poor.  Numerous  small  ulcers  on  gums,  on  inner  surface 
of  lips,  and  on  frenum  of  tongue.  Nitrate  of  silver  (solid) 
applied  to  each.  The  iodide  of  potassium  treatment  to 
be  abandoned. 

July  6th. — Patient  writes  from  his  home  in  the  countrjr 
that  the  ulcers  have  healed,  and  that  his  general  health  is 
again  perfectly  good.  His  hearing,  however,  remains 
poor. 

The  last  report  which  I  received  was  dated  September 
nth.  The  ulcers  had  reappeared  on  his  gums  and  lips 
toward  the  end  of  July,  and  he  had  suffered  more  or  less 
from  "  malaria  "  during  this  period  of  nine  or  ten  weeks. 
At  one  time  the  hearing  had  been  even  better  than  it 
was  in  New  York  during  the  previous  month  of  March. 
It  soon  diminished  again,  however,  and  was,  at  the  date 
of  his  letter,  about  as  bad  as  when  I  first  saw  him. 

Case  III. — Male;  forty-five  years  of  age ;  February  24, 
1882.  Deafness  began  to  develop  four  years  previously, 
and  in  about  two  years  it  had  become  so  marked  that  it 
was  only  with  great  difficulty  that  he  could  hear  what  was 
said  to  him.  During  the  past  two  years  the  hearing  bad 
remained  unchanged.  Syphilitic  manifestations  twenty- 
five  years  previously.  He  had  also,  up  to  a  compara- 
tively recent  date,  used  alcoholic  stimulants  to  excess. 
Recently  he  had  had  some  difficulty  with  his  eyesight, 
and  there  had  been  some  paresis  of  the  muscles  of  the 
lower  extremities. 

Treatment  (by  Dr.  E.  D.  Hudson,  Jr.,  of  this  city): 
inunctions  with  a  five  per  cent  Squibb's  oleate  of  mercury, 
and  increasing  doses  of  the  iodide  of  potassium ;  begin- 
ning with  five  minims  of  a  saturated  solution,  to  be  taken 
three  times  daily,  and  the  dose  to  be  increased  by  five 
minims  on  alternate  days. 

On  April  6th  his  gums  began  to  be  affected,  and  the 
inunctions  were  discontinued.  Two  hundred  and  eighty- 
five  minims  of  the  iodide  of  ix)tassium  solution  taken 
daily.  No  eruption.  No  coryza.  No  discomfort  of  any 
kind. 

April  1 2th. — Three  hundred  and  fifteen  minims.  No 
improvement  in  the  hearing. 

April  20th. — Potassium  iodide  discontinued  during  the 
past  week,  but  now  to  be  resumed. 

May  4th. — He  has  taken  315  minims  daily  during  the 
past  twa  weeks,  without  any  unpleasant  effects,  but  also 
without  any  appreciable  improvement  in  the  condition  of 
the  hearing. 

Treatment  abandoned. 

Case  IV. — Male ;  fifty-two  years  of  age ;  robust 
health  ;  professional  musician  (wind  instrument)  ;  No- 
vember 2,  1883.  Patient  had  been  somewhat  hard  of 
hearing  since  1877.  In  the  left  ear  the  hearing  power 
had  been  almost,  if  not  quite,  destroyed,  but  witii  the 
right  ear  he  had  been  able  to  hear  fairly  well — ^well 
enough  for  all  ordinary  purposes  of  daily  life.  On  Oc- 
tober 27th  he  began  to  grow  quite  deaf  in  the  right  ear, 
and  in  less  than  forty-eight  hours  he  had  entirely  lost  the 
hearing  in  that  ear.  There  was  an  entire  absence  of 
anything  like  vertigo,  but  the  tinnitus  was  very  marked, 
and  extremely  distressing.  He  spoke  of  it  as  a  terrible 
rushing  sound  in  his  ear.  At  the  time  when  I  saw  him 
(November  2d)  I  was  obliged  to  communicate  with  him 
in  writing,  as  he  was  apparently  perfectly  deaf  in  both  ^ 
ears.  Both  middle  ears  and  external  auditory  canals 
seemed  to  be  essentially  normal.     No  history  of  syphilis. 


Sq)tember  6,  1884.] 


THE  MEDICAL  RECORD. 


259 


At  first  I  was  disposed  to  look  upon  the  deafness  as  due 

to  the  rapture  of  a  blood-vessel  and  the  escape  of  blood 

into  the  lab^nth.     On  this  supposition  I  had  three 

leeches  applied  immediately  to  the  region  of  the  right 
tragus,  and  advised  the  promotion  of  free  after-bleeding. 
A  blister  was  also  applied  behind  the  ear,  and  four  or 
fife  days  later  a  second  one  was  applied  at  the  same 
spot  No  beneficial  effects  following  these  measures,  I 
prescribed  a  satiurated  solution  of  the  iodide  of  sodium. 
Of  this  he  took  at  first  30  minims  daily,  and  then 
gradoaUy  increased  the  dose,  until,  from  December  i8th 
to  December  24th,  he  took  daily  360  minims.  He  ex- 
perienced no  unpleasant  symptoms  from  the  large  doses 
beyond  a  scanty  eruption  on  his  forehead,  and  some 
general  malaise  toward  the  end  of  this  period.  The  hear- 
ing, however,  was  not  restored  in  the  slightest  degree, 
ai2  the  tinnitus  was  not  appreciably  diminished.  Treat- 
ment then  abandoned. 

Case  V. — ^Male  ;  forty  years  of  age ;  apparently  in 
robust  health  (patieht  of  Drs.  George  A.  Peters  and 
Wm.  A.  Valentine);  May  24,  1884.  Two  days  pre- 
viously he  had  experienced  decided  vertigo,  nausea,  and 
double  tinnitus.  In  a  short  time  vomiting  of  mucus  and 
bile  set  in,  and  continued,  at  intervals,  for  several  hours. 
He  then  made  the  discovery  that  he  had  entirely  lost  the 
healing  power  of  both  ears.  Examination  of  the  ears 
revealed  no  lesions  other  than  those  of  a  chronic  catarrhal 
inflammation  of  both  tympana.  He  declared  that  he 
could  hear  the  ticking  of  my  watch  in  his  right  ear,  but 
he  was  not  able  to  distinguish  spoken  words. 

As  the  patient  had  been  under  my  care  ten  years 
previously  for  syphilitic  sore  throat  with  subacute  otitis 
media,  I  advised  a  trial  of  the  mixed  treatment  described 
above. 

May  28th. — The  vertigo  has  largely  disappeared,  and 
patient  says  that  he  can  understand  whatPhis  wife  says  to 
him  in  a  loud,  shrill  voice. 

On  July  7th  I  learned  from  Dr.  Valentine  that  little  or 
no  improvement  had  taken  place  in  the  hearing,  that  the 
tinnitus  was  still  marked,  and  that  he  could  not  as  yet 
walk  steadily.  Up  to  that  time  he  had  not  been  able  to 
take  more  than  90  grains  of  the  iodide  of  potassium 
daily.  It  was  found  Uiat  he  could  take  this  more  com- 
fortably than  he  could  the  iodide  of  sodium,  which 
nauseated  him. 

July  14th. — Patient  has  been  taking  180  grains  daily, 
but  without  any  effect  upon  the  hearing.  On  the  nth 
the  treatment  was  suspended,  as  patient's  stomach  began 
to  rebel 

Soon  afterward  the  treatment  was  resumed,  and  before 
^e  end  of  the  month  the  daily  quantity  of  potassium 
iodide  taken  by  the  patient  had  reached  270  grains.  He 
had  taken  this  quantity  daily  for  a  period  of  one  week, 
when  it  was  found  necessary  to  stop  the  treatment  alto- 
gether, as  his  general  condition  showed  that  it  was  doing 
him  more  harm  than  good  It  certainly  produced  little  or 
no  effect  upon  the  hearing  power,  as  it  was  still  found 
necessary  to  communicate  with  him  in  writing. 

It  is  not  possible  to  draw  any  very  satisfactory  con- 
clusion from  such  a  small  number  of  cases.  For  exam- 
ple, the  treatment  failed  to  accomplish  anything  worthy 
the  name  of  improvement  in  all  five  instances,  and  yet, 
as  has  been  observed  in  the  cases  reported  by  Dr.  Roosa, 
3nd  in  those  reported  by  Dr.  Webster,  essentially  the 
ame  treatment  may  accomplish  strikingly  favorable  re- 
sults. I  have  compared  these  cases  very  carefully  with 
those  reported  above,  in  the  hope  that  I  might  find  out 
certain  distinguishing  features  which  would  enable  us  to 
divide  all  such  cases  into  two  classes,  viz.,  those  which 
ought  be  benefited  by  treatment,  and  those  in  which 
treatment  would  almost  certainly  fail.  I  have  not,  how- 
ever, been  able  to  find  any  such  distinguishing  character- 
istics. The  only  plausible  explanation  that  I  can  jgive 
of  the  infrequency  of  our  successes  is  this :  A  syphiUtic 
gonuna  in  the  labyrinth,  and  especially  in  the  cochlea, 
will  rarely  &il  to  produce  damage  from  which  recovery 


is  scarcely  possible.  Treatment  may  lead  to  the  ab- 
sorption of  the  gumma,  but  it  cannot  readjust  and  render 
fimctionally  useful  those  delicate  and  carefully  adjusted 
organs  which  the  tumor  has  disarranged,  and  perhaps 
even  destroyed.  In  the  brain  excellent  compensatory 
provision  seems  to  have  been  made  for  the  pressure 
caused  by  a  gumma  or  other  morbid  growth;  in  the 
labyrinth,  on  the  other  hand,  the  rigidity  of  the  sur- 
rounding walls  and  the  paucity  as  well  as  smallness  of 
the  blo<K]-vessels,  almost  preclude  the  possibility  of  com- 
pensation. On  physiological  grounds,  therefore,  I  feel 
confident  that  such 'cures  as  those  reported  by  Dr.  Roosa 
and  Dr.  Webster  will  always  be  exceptional.  In  these 
cases  we  may  assume  that  the  pressure  had  gone  only  so 
far  as  to  suspend  for  a  time  the  vibratory  power  of  the 
cochlear  structures,  but  had  not  destroyed  or  even  seri- 
ously disarranged  them.  It  is  also  possible  that  the 
gumma  may  occupy  a  position  in  the  vicinity  of  the  oval 
window  and  foot-plate  of  the  stirrup,  or  in  that  of  the 
secondary  tympanic  membrane.  A  lesion  so  situated 
would  be  competent  to  annul  the  pow^r  of  hearing,  but 
it  would  not  necessarily  destroy  it. 

In  the  next  place,  it  will  be  obsen/ed  that  in  the  fa- 
vorable cases  the  improvement  b^gan  to  show  itself  as 
early  as  during  the  second  or  thiid  week  of  the  iodide  of 
potassium  treatment.  This  would  suggest  the  question 
whether  it  is  really  necessary  to  push  the  doses  to  the 
extreme  limits  recorded  above  (viz.,  270  gr.,  315  gr.,  360 
gr.,  525  gr.,  and  "  several  hundred  grains "  daily).  This  is 
a  question  which  cannot  be  satisfactorily  answered  until 
we  shall  have  accumulated  a  greater  array  of  evidence. 
I  am  disposed,  however,  to  adopt  for  the  present  the 
rule  of  not  giving  more  than  from  one  to  two  drachms 
daily  in  those  cases  in  which  commencing  improvement 
is  observed  during  the  second  or  third  week  of  treatment. 

In  conclusion,  I  will  state  that  in  the  first  years  of 
practice  I  must  have  registered  some  cases  of  S3rphilitic 
disease  of  the  labyrinth  as  instances  of  ''  M^ni^re's  dis- 
ease," and  I  believe  that  this  error — if  error  it  be — has 
probably  been  committed  by  other  specialists. 


HAY  ASTHMA— CAN  IT  BE  RELIEVED  ?     . 
By  WILUAM  JUDKINS,  M.D., 

LATB  PKOPSSSOS  OP  PHYSIOLOGY,  BTC.,  ONaNNATI  COLLBOB  OP    BiKDICINK  AND 
SUXGBtY,  aNCUniATI,  O. 

I  FEEL  that  I  should  be  sadly  derelict  of  duty  did  I  not 
give  to  the  profession,  and  through  them  to  the  laity,  my 
successful  treatment  of  this  obstinate  and  distressing 
complaint  Though  only  the  record  of  one  case,  the 
result  is  so  gratifying  to  the  patient,  her  family,  and  my- 
self; that  I  feel  justified  in  sending  these  few  lines  regard- 
ing it,  in  hope  of  benefiting  others. 

Mrs. ,  aged  twenty-eight,  married,  mother  of  two 

children,  the  youngest  four  and  a  half  months  old.  Has 
been  subject  to  an  annual  attack  of  ha^  fever  for  fourteen 
years,  and  frequently  with  complications  of  a  severe 
character.  Last  year  she  suflfered  an  attack  of  bronchitis 
during  the  latter  part  of  the  ^asthmatic  stage,  that 
came  near  proving  fatal.  Convalescence  slow.  This 
case  first  came  under  my  charge  in  1880.  The  attack 
that  year  was  aggravated  in  a  measure  by  pre^ancy. 
The  only  thing  at  that  rime  that  gave  any  relief  was 
'*  milk  punch,*'  in  the  proportion  of  whiskey,  2  oz.;  milk, 
8  oz.  The  relief  obtained  from  this  was  only  tenaporary, 
when  more  would  be  administered ;  but  at  no  time  was 
intoxication  produced,  though  the  remedy  was  given  for 
several  days  in  succession.  In  1881  a  reputed  "hay- 
fever  resort  "—Oakland,  Md. — was  tried  for  a  part  of  the 
season,  but  no  benefit  was  derived,  the  attack  being  fully 
as  severe  as  at  any  previous  time.  1882  and  1883  were 
equally  as  bad,  the  complication  of  bronchitis  spoken  of 
above  coming  on  last  year,  which  almost  caused  death. 
This  year  prophylactic  treatment  was  commenced,  some 
two  weeks  before  her  expected  attack,  of  valerianate  of 


26o 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


zinc,  gr.  i.,  and  pill  assafoetida  co.,  gr.  ii.,  combined  in  cap- 
sules, one  A.M.  and  p.m.,  as  recommended  by  Dr.  Morell 
Mackenzie,  of  London.  It  disagreed  with  her  stomach, 
and  was  discontinued  for  three  days  and  then  again  taken 
with  no  bad  effect  For  five  days  after  her  usual  time 
for  the  appearance  of  the  dreaded  affection  all  was  se- 
rene. The  night  of  the  20th  inst.  difficulty  of  breathing 
to  a  limited  extent  set  in.  My  attention  had  been  called 
to  a  case  of  bronchial  asthma,  who  obtained  relief  from 
the  use  of  acid  hydriodic,  and  I  immediately  ordered  my 
patient  to  commence  its  use  early  on  the  morning  of  the 
next  day,  the  21st.  The  effect,  in  conjunction  with  coun- 
ter-irritation in  the  shape  of  Rigollof  s  mustard  leaves  at 
the  wrist-joints,  was  simply  magical^  breathing  became 
more  and  more  easy  as  she  continued  the  remedies.  A 
thunder-storm  came  up  that  night,  twelve  hours  after 
commencing  the  medicine,  and  for  half  an  hour  she  was 
somewhat  ''  stuffed  up,''  as  she  expressed  it,  but  had  a 
good  night's  rest.  Ever  since  then  she  has  been  easy — 
now  a  week — but  is  exercising  all  precautionary  measures 
against  taking  cold,  for  fear  of  a  relapse. 

I  can  truly  say  that  about  every  remedy  suggested  and 
recommended  fi'om  the  time  that  Bostock  first  wrote  on 
the  subject,  in  18 19,  had  been  tried,  but  nothing  has 
ever  given  the  relief  and  sense  of  comfort  that  this  did. 
One  word  more  and  I  am  done  :  the  form  of  administra- 
tion was  that  of  the  syrup — a  teaspoonful  every  hour  or 
two,  until  relief  If  necessary  double  the  dose.  The 
syrup,  as  prepared  by  Mr.  Gardner — Schieflfelin  &  Co.'s 
chemist — was  the  special  brand,  though  where  that  is  not 
accessible,  I  imagine  the  regular  acid  of  the  dispensatory 
on  a  lump  of  sugar,  gtt.  3  to  5,  would  be  equally  as  effi- 
cacious. The  mustard  leaves  are  applied  as  soon  as  the 
first  dose  is  given. 

Since  commencing  the  acid  treatment,  my  brother.  Eh*. 
C.  P.  Judkins,  has  prescribed  it  in  another  case,  that  of 
a  married  lady  who  suffered  intensely  with  the  asthmatic 
spaptoms,  with  perfect  relief,  that  so  far  has  been  con- 
tmuous,  and  as  in  my  own  patient,  bids  fair  to  con- 
tinue so. 

The  capsules  were  discontinued  when  commencing  the 
use  of  the  acid. 

ai6  ^cs  Strbbt,  August  38,  X884. 


THE  DISCUSSION  ON  CHOLERA  AND  THE 
COMMA-BACILLUS  IN  THE  BERLIN  CON- 
FERENCE. 

We  gave  last  week  an  abstract  of  Dr.  Koch's  lecture 
on  cholera  and  the  comma-bacillus,  delivered  at  the  Im- 
perial Board  of  Health,  in  Berlin.  After  describing  the 
bacillus  and  its  relation  to  cholera,  he  spoke  of  the  con- 
ditions under  which  it  thrives  in  its  home  in  India. 
Southern  Bengal  is  a  flat  country,  elevated  but  little 
above  the  level  of  the  sea,  and  is  almost  completely 
submerged  during  the  rainy  season.  In  order  to  escape 
the  flood,  the  inhabitants  build  their  houses  on  artificial 
elevations,  made  by  piling  up  the  earth  taken  from  the 
side  of  the  foundation.  It  thus  happens  that  beside 
every  house  or  group  of  houses  there  is  a  large  hole  filled 
with  water.  These  tanks,  as  they  are  called,  are  very 
numerous,  there  being  a  thousand  or  more  in  the  suburbs 
of  Calcutta  alone.  The  huts  of  the  natives  have  no 
privies  attached,  and  every  kind  of  dirt  is  thown  directly 
on  the  ground,  from  whence  it  finds  its  way  naturally, 
into  the  neighboring  tanks.  A  system  of  sewerage  was 
introduced  m  1865,  and  at  the  same  time  measures  were 
taken  to  furnish  the  city  with  filtered  water  brought  from 
the  river  some  miles  above  Calcutta.  No  improvement 
in  the  health  of  the  city  was  noticed  during  the  first  few 
years  that  the  canal  system  was  being  extended,  but  as 
soon  as  the  pure  water  supply  was  obtained,  in  1870,  the 
cholera  decreased,  and  the  death-rate  from  this  cause  has 
not  since  then  surpassed,  on  an  average,  one-third  of  its 
former  figures.     In  the  suburbs,  between  which  and  the 


city  there  is  a  constant  intercourse,  but  to  which  the 
water  supply  has  not  been  extended,  the  cholera  is  as 
prevalent  as  before.  Similar  and  even  more  striking 
instances  of  the  influence  of  the  water  supply  were  ftir- 
nished  by  other  cities  and  places  in  India  These  cases 
were  cited  to  show  the  value  of  pure  water,  but  Dr.  Koch 
did  not  wish  to  be  considered  a  partisan  of  an  exclusive 
drinking-water  theory,  for  he  thought  that  cholera  might 
be  propagated  in  many  different  ways  in  any  particular 
locality,  and  further,  that  each  locality  had  its  own 
peculiar  conditions  favorable  to  the  spread  of  the  dis- 
ease. 

In  former  times  the  cholera  travelled  along  the  cara- 
van routes  from  India  through  Persia  and  £ence  into 
southern  Europe,  but  now  it  takes  the  more  speedy  way 
through  the  Red  Sea  and  the  Suez  Canal.  There  is 
little  likelihood  in  these  times  of  the  disease  coming  over- 
land, but  the  danger  of  its  introduction  by  way  of  the 
Red  Sea  is  becommg  greater  every  year.  From  Bombay, 
which  is  seldom  free  firom  cholera,  to  Egypt  is  a  matter 
of  only  eleven  days,  to  Italy  sixteen  da3rs,  and  not  more 
than  twenty  days,  at  the  most,  to  the  South  of  France. 
As  regards  the  danger  of  the  transportation  of  cholera  in 
ships,  however,  much  depends  upon  the  character  of  the 
vessel.  Epidemics  occur  only  on  those  ships  in  which 
large  numbers  of  men  are  crowded  together.  In  mer- 
chant vessels  and  freighters,  although  there  may  be  a  few 
cases  of  cholera  during  the  first  days  of  the  voyage,  the 
disease  never  becomes  epidemic  nor  continues  for  a 
long  time. 

In  concluding,  the  lecturer  spoke  briefly  of  the  value 
of  the  discovery  of  the  cholera  bacillus.  In  the  first 
place,  it  is  of  the  greatest  importance  to  be  able  to 
diagnose  correctly  the  first  case  of  cholera  occurring  in  a 
country  or  in  any  locality.  This,  he  believed,  could  now 
be  done  with  absolute  certainty  if  the  comma^bacillus 
were  found  in  the  dejections.  And  fiirther,  when  the 
cause  of  a  disease  and  its  properties  are  thoroughly  un- 
derstood, we  are  in  condition  to  determine  with  accu- 
racy its  etiological  relations,  and  also  to  institute  a  rational 
and  effectual  mode  of  treatment.  Not  the  least  impor- 
tant consideration  is  the  hope,  now  offered,  of  discovering 
a  certain  means  of  prophylaxis. 

At  the  close  of  Dr.  Koch's  lecture,  Professor  Virchow 
announced  that  a  second  conference  would  be  held  on 
the  evening  of  July  29th  for  the  purpose  of  discussing 
the  various  points  suggested  by  the  paper. 

After  the  members  had  re-assembled.  Professor  Vir- 
chow stated  that  in  order  to  keep  the  discussion  within 
bounds,  certain  questions  had  been  prepared,  covering 
all  the  points  raised  in  the  lecture,  upon  which  those 
present  were  requested  to  express  their  views.  The 
first  question  was : 

IS  CHOLERA  CAUSED  BY  AX   INFECTIOUS   MATERIAL  ORIGI- 
NATING ONLY   IN   INDIA? 

This  was  answered  in  the  affirmative.  Herr  Hirsch 
said  that  in  the  Sanitary  Conference,  held  in  Vienna  in 
1874,  the  members  were  unanimous  in  the  opinion  that 
cholera  occurs  in  Europe  in  consequuence  only  of  the 
introduction  of  the  specific  poison  from  India.  This 
unanimity  was  the  more  noteworthy  as  on  other  ques- 
tions relating  to  cholera  there  were  many  conflicting 
opinions  expressed  by  the  delegates. 

The  next  question  proposed  for  discussion  was : 

IS  THE  INFECTIOUS  MATERLAL  CONTAINED  ONLY  IN  THE 
DEJECTIONS,  AND  LATER  ALSO  IN  THE  VOMITED  MAT- 
TERS, OR  IS  IT  FOUND  ALSO  IN  THE  BLOOD,  URINE, 
SWEAT,  AND  EXPIRED  AIR  ? 

Dr.  Koch  stated  that  it  was  his  firm  conviction  that 
the  cholera  poison  was  present  in  the  dejections  only. 
In  exceptional  cases  it  was  found  in  the  vomited  mat- 
ters, but  only  when  these  matters  were  of  intestinal  ori- 
gin. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


261 


The  two  following  points  were  considered  together  : 

IS  THE  PRESENCE  OF  THE  COMMA- BACILLUS  OF  DIAGNOSTIC 
IMPORT  ?  AND,  IS  THE  INFECTIOUS  MATERIAL  OF  CHOL- 
ERA IDENTICAL  WITH  THE  COMMA-BACILLUS  ? 

Professor  Virchow  said  that,  in  regard  to  the  second 
point,  some  elements  of  absolute  certainty  were  wanting. 
On  the  one  hand,  no  one  had  as  yet  succeeded  in  pro- 
ducing cholera  in  the  lower  animals  by  inoculation  with 
the  comma*bacilfais.  Dr.  Richards  had  indeed  fed  hogs 
apon  intestinal  matters  taken  from  cholera  patients,  and 
the  animals  had  sickened  and  died,  but  Dr.  Koch  main- 
tained that  death  in  these  cases  was  caused  by  poisoning 
and  that  the  disease  produced  was  not  cholera.  He 
thonght  it  very  desirable  that  comparative  experiments 
sboold  be  made  with  pure  cultures  of  the  conuna-bacillus 
and  with  the  cholera  dejections,  for  at  present  it  seemed 
possible  that  there  might  be  some  other  infectious  mate- 
rial in  addition  to  the  bacillus.  On  the  other  hand,  the 
whole  history  of  cholera,  its  mode  of  origin  and  spread, 
seemed  inexplicable,  except  upon  the  theory  of  a  living 
contagium.  And  among  all  the  micro-organisms  found 
in  Ae  cholera  stools  the  comma-bacillus  alone  could  with 
any  degree  of  probabiHty  be  accused  of  causing  the  dis- 
ease. The  question  whether  there  was  any  other  disease 
in  which  tlm  particular  micro-organism  was  present 
coold  not  yet  be  answered  with  certainty,  and  indeed,  it 
might  be  many  years  before  it  could  be  affirmed  or  de- 
ni^  with  strictly  scientific  accuracy.  But  for  the  present 
the  speaker  thought  that  it  was  incumbent  upon  the  sani- 
tary authorities  to  act  as  though  the  comma-bacillus  was 
the  actual  and  certain  cause  d[  cholera. 

Dr.  Koch  remarked  that  his  reason  for  believing  that 
the  hogs  in  Dr.  Richards^  experiment  were  poisoned, 
was  that  they  died  so  speedily,  within  two  and  a  half 
hoars.  And  then  every  attempt  at  a  reproduction  of  the 
infectious  material  in  these  cases  failed.  He  thought, 
however,  that  the  experiments  told  in  no  way  against  the 
badllns  theory;  on  the  contrary,  they  showed  that  a 
poisonous  substance  was  formed  in  the  intestinal  canal 
under  the  influence  of  the  conuna-bacillus.  In  regard  to 
a  point  suggested  by  Dr.  Hirsch,  the  speaker  said  that  he 
had  examined  sections  of  the  intestinal  mucous  membrane 
taken  fiom  a  man  dead  of  cholera  morbus,  but  had  found 
no  comma-bacilli,  although  there  were  swarms  of  other 
miao-organisms  present.  In  answer  to  a  question  asked 
by  Professor  Virchow,  whether  in  a  doubtiful  case,  pre- 
senting the  symptoms  of  either  cholera  morbus  or  Asiatic 
dK>lera,  but  in  which  simple  microscopic  examination  of 
the  stools  had  revealed  the  presence  of  countless  comma- 
hacilli,  he  would  hesitate  to  make  a  diagnosis.  Dr. 
Kodi  asserted  emphatically  that  he  would  not.  He  said, 
however,  that  it  was  seldom  possible  to  find  the  micro- 
oiganisms  in  great  numbers  in  a  microscopical  examina* 
tion  of  the  dejections.  In  most  cases  the  culture  method 
is  necessary,  and  this  never  (ails.  This  question  of  an 
eariy  diagnosis  of  cholera,  he  continued,  is  a  very  impor- 
tant one  indeed,  for  if  the  first  case  in  any  locality  be 
recognized  inunediately,  it  can  be  isolated,  and  thus  the 
ipiead  of  the  disease  be  prevented  But  if  the  diagnosis 
he  delayed  aniil  half  a  dozen  or  more  cases  have  occurred, 
then  all  control  over  the  outbreak  is  lost.  Regarding  the 
difficulties  of  a  general  use  of  this  method,  he  had  onl^ 
tD  say  that  the  process  of  staining  the  tubercle  bacilli, 
vioch  was  now  very  generally  understood,  was  far  more 
difficult  than  was  that  of  cultivating  the  commarbacillus.  In 
answer  to  an  inquiry  of  Dr.  Schubert,  he  said  that  he  had 
foood  the  bacilli  present  very  early  in  the  disease,  within 
t  few  hours,  and  he  could  state  positively  that  die  first 
colorless  watery  stools  contained  them  in  great  numbere. 
Another  hypothetical  question  was  proposed,  whether  in 
^  case  of  a  person  coming  from  a  cholera  district  and 
presenting  symptoms  of  cholera,  but  in  whose  stools  no 
oomnui-bacilli  could  be  detected,  the  patient  should  be 
iDowed  to  go  where  he  would  or  should  be  kept  under 
observation  ?    To  this  the  speaker  replied  that  the  case 


ought  certainly  to  be  regarded  as  a  very  suspicious  one. 
But  this  was  not  exactly  a  case  in  point  A  person, 
known  to  have  come  directly  from  a  cholera  infested 
region,  who  shall  be  taken  ill  with  symptoms  of  cholera, 
ought  to  be  isolated  at  once,  there  would  be  no  necessity 
of  searching  for  the  comma-bacillus.  But  to  suppose  a 
case.  Cholera  is  now  ravaging  the  south  of  France.  A 
case  with  S3rmptoms  resembling  those  of  cholera  occurs 
suddenly  in  a  German  city,  and  comma>bacilli  are  found 
in  the  dejections.  Now,  die  cholera  poison  is  already  in 
the  city,  and  much  more  active  measures  must  be  taken 
than  simply  to  bury  the  corpse  and  disinfect  the  sur- 
roundings. 

It  having  been  objected  that  the  culture  of  the  comma- 
bacillus  required  a  well-appointed  laboratory,  and  the 
possession  of  considerable  skill  and  experience  on  the 
part  of  the  physician,  Dr.  Koch  explained  the  method 
employed  by  him.  The  gelatine  used  could  now  be 
bought  in  the  shops.  All  that  was  necessary  was  to  warm 
the  gelatine,  mix  it  with  a  flocculus  of  mucus  from  the 
stools,  and  then  pour  it  out  on  a  piece  of  glass.  This  is 
then  placed  under  a  glass  bell,  or,  if  the  latter  cannot 
be  had,  between  two  plates,  as  was  done  in  the  experi- 
ments made  in  Calcutta.  It  is  easy  enou^  to  obtain 
material  for  examination,  for  any  of  the  dothes  soiled 
with  the  passages  will  furnish  enough  mucous  flocculi  for 
the  purpose.  A  special  warming  apparatus  is  not  neces- 
sary, for  the  ordinary  summer  temperature  was  over  1 7^ 
C.  (62.6°  F.),  which  was  sufficient  for  the  development 
of  the  badllL 

The  next  two  questions  proposed  were : 

DOSS  THE  INFECnOUS  MATERIilL  POSSESS  A  GREAT 
POWER  OF  RESISTANCE,  HAS  n  A  STAGS  OF  PERMA- 
NENCE ?  AND,  IS  IT  DESTROYED  IN  A  SHORT  TIME  BY 
DRYING  ? 

Dr.  Koch  said  that  his  opinion  on  this  point  was 
based  not  only  upon  his  experiments  with  the  comma- 
bacillus,  but  also  upon  the  universal  experience  with 
cholera.  There  was  no  case  known  with  certainty  in 
which  the  poison  of  cholera  had  remained  latent  for  a 
great  length  of  time,  and  had  then  renewed  its  activity. 

Dr.  Hirsch  related  his  experience  in  the  cholera  epi- 
demic which  had  visited  Posen  and  West  Prussia  in  1873. 
He  had  seen  many  cases  in  which  the  first  persons  at- 
tacked in  a  village  were  women  who  had  washed  soiled 
clothing  brought  from  infected  districts.  In  several 
of  these  cases  the  clothes  were  allowed  to  remain 
some  time  untouched,  before  being  unpacked  and 
cleaned. 

In  reply  to  a  question  of  Dr.  Koch  he  said  that  the 
clothes  in  some  cases  were  left  for  five  or  six  dajrs,  long 
enough  for  them  to  become  thoroughly  dry.  It  had  been 
admitted  by  the  lecturer,  he  continued,  that  under  con- 
ditions  of  moisture  the  commarbacillus  might  remain 
latent  for  an  almost  unlimited  period.  Why,  &en,  was  it 
not  possible,  in  a  place  where  cholera  had  been  epidemic, 
for  the  bacUlus  to  romain  alive  in  moist  earth  or  other 
damp  places  during  such  time  as  the  other  conditions 
were  not  favorable  to  its  developn>ent,  and  then  to  be- 
come active  and  give  occasion  to  a  new  epidemic  as  soon 
as  a  favorable  conjunction  of  circumstances  should 
arise? 

Dr.  Koch  said  that  he  had  admitted  the  possibility  of 
such  an  occurrence,  after  having  found  that  the  comma- 
bacillus  could  endure  a  very  low  temperature  and  could 
exist  outside  of  the  human  body,  in  potato,  gelatine,  and 
damp  clothing,  for  example,  for  an  indefinite  time.  He 
thought  the  question  a  very  important  one  but  which  the 
future  only  could  solve.  The  ground,  the  water,  and 
everything  that  could  offer  an  asylum  to  the  bacillus 
ought  to  be  examined  for  a  long  time  after  the  disappear- 
ance of  cholera  firom  a  place.  Such  investigations  could 
not  be  made  in  India,  because  the  cholera  was  always 
there,  but  could  be  undertaken  upon  the  subsidence  of 
an  epidemic  in  Europe. 


262 


THE5  MEDICAL  RECORD. 


[September  6,  1884. 


The  next  question  proposed  for  discussion  was  : 

CAN    THE    INFECTIOUS    MATERIAL    ENTER    THE    BODY    BY 
OTHER  CHANNELS  THAN  THE  DIOESTIVC  TRACT? 

The  discussion  was  not  confined  strictly  to  this  point, 
but  turned  rather  upon  the  question  whether  the  infec- 
tious material  could  be.  transported  through  the  air. 
Several  of  those  present  thought  that  it  might  be  so 
carried,  at  least  for  short  distances,  and  instanced  the 
frequency  with  which  those  who  handled  the  bodies  of 
persons  dead  of  cholera  were  themselves  attacked  with 
the  disease.  Dr.  Leyden  thought  it  very  possible  for  the 
germs  to  be  carried  up  into  the  air  with  fine  particles  of 
moisture  during  the  rapid  evaporation  of  contaminated 
fluid. 

These  views  were  very  strongly  opposed  by  Dr.  Koch. 
He  thought  it  much  more  probable  that  the  disease  oc- 
curring in  those  who  handled  the  corpses  of  cholera 
patients  was  due  to  a  want  of  cleanliness  on  the  part  of 
those  individuals.  Their  hands  became  soiled  and  then 
they  took  food  without  washing.  The  physicians  and 
nurses  in  hospitals  who  were  careful  in  washing  them- 
selves were  no  more  liable  to  cholera  than  other  people, 
uid  yet,  if  the  poison  were  carried  through  the  air,  they 
ought  to  be  among  the  principal  sufferers.  The  cholera 
bacillus  was  killed  by  drying,  and  it  could  be  carried 
through  the  air  only  in  watery  spray  or  in  bubbles;  in  dust 
it  could  not  live.  In  regard  to  cases  in  which  the  disease 
was  alleged  to  have  been  carried  by  healthy  individuals, 
the  explanation  would  probably  be  simplified  were  all 
the  circumstances  known.  Very  possibly  food  or  other 
articles  were  carried  firom  the  house  of  the  cholera 
patient,  or  the  apparently  healthy  individual  might  have 
had  a  very  mild  attack  of  cholera  which  passed  un- 
noticed. 

IS  THE  INFECTIOUS  MATERIAL  REPRODUCED  IN  THE 
HUMAN  SUBJECT,  OR  DOES  THIS  TAKE  PLACE  IN  THE 
GROUND,  SO  THAT  MEN  ACT  ONLY  AS  CARRIERS   OF  FT  ? 

Professor  Virchow  asked  whether,  since  the  comma- 
bacillus  was  an  air-breathing  organism,  the  intestinal 
canal  could  be  regarded  as  a  £a.vorable  location  for  its 
development 

Dr.  Koch  said  that  either  free  oxygen  must  be  pres- 
ent in  the  intestine,  or  at  least  such  combinations  must 
be  there  as  would  give  off  oxygen.  For  we  see  the 
bacilli  living  in  great  numbers  in  the  intestine,  and  yet 
they  cease  to  grow  outside  of  the  body  when  deprived  of 
air.  Consequently  they  must  in  some  way  obtain  oxygen 
in  the  intestine.  Other  organisms  which  require  oxygen 
for  their  exsistence,  as  the  oidium  laciis  for  example,  are 
•often  found  in  quantities  in  the  intestinal  canaL 

Professor  Virchow  thought  it  probable  that  the  bacil- 
lus was  reproduced  both  outside  and  inside  the  human 
organism.  At  least  it  was  shown  that  the  reproduction 
in  the  ground  was  possible,  but  further  than  that  we  could 
not  yet  go. 

The  next  question  proposed  was  S 

IS  A  DIRECT  TRANSPLANTATION  POSSIBLE,  OR  MUST  THE 
INFECTIOUS  MATERIAL  UNDERGO  A  SORT  OF  RIPENING 
OR  GROWTH  IN  THE  GROUND  OR  ELSEWHERE  ? 

It  was  supposed,  Dr.  Koch  said,  that  a  sort  of  ripen- 
ing of  the  cholera  germ  was  necessary,  because  the  de- 
jections were  not  infectious  when  first  passed.  This 
latter  assertion  was  based  upon  an  experiment  of  Thiersch, 
but  his  own  opinion  was  that  the  clothes  were  capable 
of  transmitting  the  disease  at  the  very  instant  that  they 
became  soiled. 

Three  questions  were  then  presented,  embracing  the 
subject  of  the  trasmission  of  cholera  by  clothing,  rags, 
merchandise,  food,  etc.  Dr.  Skrzeczka  thought  it  very 
reasonable  to  suppose  that  the  disease-germs  could  be 
carried  in  rags,  for  these  were  packed  in  large  bales,  and 
if  the  rags  were  not  thoroughly  dried,  those  in  the  cen- 


tre of  the  bale  might  remain  moist  for  an^indefinite 
period. 

Dr.  Koch  answered  that  this  question  of  the  possibility 
of  infection  through  rags  was  discussed  in  the  cholera 
congresses  of  Vienna  and  Constantinople,  and  nobody 
was  able  to  furnish  an  instance  of  the  spread  of  the  dis- 
ease by  this  means.  The  rags  should,  he  thought,  be 
thoroughly  dried  before  being  packed.  But  it  seemed  to 
be  of  little  use  to  prevent  the  importation  of  rags,  if 
human  intercourse  was  to  be  allowed  The  danger  of 
the  introduction  of  cholera  through  apparently  healthy 
individuals,  a  danger  which  cannot  be  guarded  against,  is 
far  greater  than  that  of  transmitting  the  disease  by  rags. 
As  regards  water  he  said  that,  as  far  as  his  experience 
went,  the  comma-bacilli  die  in  clean  water,  not  imme- 
diately, but  within  a  few  days. 

The  remaining  questions  were  : 

IS  A  SPECIAL  INDIVIDUAL  PREDISPOSmON  NECESSARY  FOR 
THE  ACTION  OF  THE  INFECTIOUS  MATERIAL  ?  WHAT  IS 
THE  PERIOD  OF  INCUBATION  ?  DOES  ONE  ATTACK  COK- 
FBR  IMMUNITY  FOR  A  CERTAIN  LENGTH  OF  TIME  ?  AND, 
CAN  THE  MODE  OF  ACTION  OF  THE  BACILLI  BE  RE- 
GARDED AS  A  POISONING  ? 

Dr.  Leyden  thought  that  one  attack  did  confer  a  de- 
ipree  of  inmiunity  against  subsequent  attacks,  yet  this 
immunity  was  not  absolute,  for  cases  had  been  reported 
in  which  an  individual  had  suffered  from  cholera  several 
rimes  during  the  same  epidemic. 

Dr.  Hirsch  stated  that  in  the  epidemic  studied  by 
him,  in  1873,  ^^  period  of  incubation  seemed  to  vary  be- 
tween two  and  four  days. 

Professor  Virchow  then  closed  the  diiscussion  by 
tendering  his  thanks  to  Dr.  Koch  for  the  lucid  report 
which  he  had  given  of  his  studies  of  the  comma-badlliis, 
and  he  said  that  the  members  would  probably  be  called 
together  again  to  discuss  these  questions,  and  to  impart 
any  new  experiences  which  they  might  have  gained  in  re- 
gard to  the  prevention  or  cure  of  cholera. 


Pernicious  Malarial  Attacks  of  Unusual  Type.— 
The  following  are  the  conclusions  of  a  paper  read  by  Dr. 
Besnier  at  a  recent  meeting  of  the  Soci6t6  de  M ^dedne  de 
VBns  {r  Union  Afidicale,  July  26,  1884):  i.  Certain 
chronic  diseases  or  morbid  conditions,  existing  prior  to 
the  malarial  attack^  and  giving  rise  in  their  course  to 
more  or  less  grave  secondary  s^ptoms,  or  manifesting 
themselves  by  repeated  functional  disturbances,  may 
sometimes  so  influence  an  intermittent  fever  as  to  render 
it  abnormal  or  pernicious.  2.  In  such  cases  the  form  of 
the  pernicious  attack  is  in  direct  relation  with  the  antece- 
dent disease.  It  resembles  in  its  prominent  symptoms 
one  or  other  of  the  secondary  accidents  or  the  functional 
troubles  of  this  disease,  but  in  an  aggravated  degree,  j 
The  attack  b  thus  more  or  less  masked  by  the  antec^ent 
malady  and  may  readily  escape  recognition.  3.  The 
morbid  states  which  precede  the  fever  and  which  impress 
upon  it  their  form,  may  be  very  slight  and  compatible 
with  aU  the  exigencies  of  ordinary  life.  The  malaria,  on 
the  other  hand,  may  have  been  contracted  in  an  infectedre- 
gion  and  may  reveal  itself  for  the  first  time  long  after  the 
patient  has  left  that  country.  The  pernicious  attack  may 
thus  be  more  insidious  and  more  sudden  in  its  onset 
than  are  malarial  fevers  ordinarily.  4.  These  pernicious 
paroxysms  owe  their  gravi^  apparentiy  less  to  the  malaria 
than  to  the  antecedent  disease  upon  which  the  malaria 
has  engrafted  itself.  They  occur  with  perhaps  greater 
frequency  in  non-malarious  regions.  They  yield,  as  a 
rule,  readily  to  quinine,  even  in  moderate  doses.  The 
antecedent  affections  in  the  cases  studied  by  Dr.  Besnier, 
and  upon  which  he  based  his  conclusions,  were :  arterial 
atheroma  with  encephalic  troubles,  diabetes  accompanied 
with  albuminuria,  and  angina  pectoris.  The  pernicious 
paroxysms  assumed  three  very  distinct  types :  a  delirious, 
a  comatose,  and  a  cardialgic  form. 


Septembef  6,  1884.] 


THE  MEDICAL  RECORD. 


263 


^epfOKts  at  ^00|yitalB* 


ROOSEVELT  HOSPITAL,   NEW  YORK. 
Rbportbd  by  J.  K  NEWCOMB,  M.D., 

HOUSB  PHYSiaAN,  K008BVSLT  HOSMTAL. 

The  following  notes,  taken  from  the  hospital  records, 
narrate  the  history  of 

^  CASB  IN  WHICH  ALL  THE  SIGNS  AND  SYMPTOMS  OF 
AORTIC  ANEURISM  WERE  SIMULATED  BY  AN  ENOR- 
MOUSLY  DILATED   HEART 

with  double  aortic  valvular  lesion. 

Thomas  K ,  New  York,  single,  laborer,  aged  sixteen, 

was  admitted  on  August  3,  1881.  Father  died  six  years 
before  of  haemoptysis,  and  mother  one  year  before  of 
uterine  cancer.  Patient  was  temperate,  denied  syphilis, 
admitted  occasional  masturbation  and  sexual  intercourse. 
Had  rheumatism  three  years  ago ;  developed  therewith 
pain  in  epigastric  and  praecordud  regions,  and  has  been 
subject  to  it  ever  since.  For  last  year  has  noticed  in- 
creasing cardiac  palpitation  and  dyspnoea.  No  oedema ; 
vision  at  times  dimmed ;  cou^h  for  past  three  months 
▼ery  severe,  of  late  worse  mornings  and  evenings ;  muco- 
purulent sputa;  quite  regular  night-sweats  for  past 
month;  no  haemoptysis;  occasional  vomiting  after 
meals;  some  emaciation;  bowels  usually  regular;  no 
urinary  changes  noted. 

On  admission  rather  poorly  nourished,  weak  and  trem- 
ulous ;  countenance  downcast ;  face  sunburnt,  but  cya^ 
nosed;  marked  dyspnoea,  least  troublesome  in  sitting 
position  ;  loose  cough,  with  copious  muco-purulent  expec- 
toration. Cannot  sleep  on  left  side ;  good  appetite  ;  some 
constipation.  Urine  1.026 ;  acid ;  no  albumen  ;  micros- 
copic examination  negative. 

Physical  examination, — Heart-«pex,  sixth  space,  one 
inch  outside  nipple  line ;  impulse  strong,  heaving,  and 
raising  considerable  area  of  chest- wall.  Dulness  on  level 
of  third  rib  from  right  border  of  sternum  to  half  an  inch 
mside  left  nipple  line.  Over  first  and  second  right  inter- 
spaces, close  to  sternum,  is  an  area  of  dulness ;  over  it  is 
felt  a  systolic  thrill  and  heard  a  loud,  rasping,  systolic 
muimur,  with  soft  diastolic  murmur  of  lower  pitch.  A 
systolic  murmur  is  heard  in  carotids  and  subclavians, 
about  equally  clearly  on  both  sides  ;  is  heard  over  ster- 
num down  to  level  of  third  right  costo-sternal  articulation, 
where  it  suddenly  becomes  softer  in  character,  while  at 
the  same  time  the  diastolic  murmur  heard  in  its  upper 
interspace  becomes  much  louder  and  sharper ;  latter 
transmitted  down  to  xiphoid  cartilage.  At  apex  is  heard 
a  short,  blowing  systolic  murmur  transmitted  to  left,  heard 
behind  in  both  vertebral  grooves,  louder  in  left,  and  as 
low  down  as  the  last  dorsal  vertebra,  A  very  distinct 
doable  murmur  is  heard  in  the  right  supra-spinous  fossa. 
The  radial  pulse  has  a  rapid  rise  and  fall,  with  a  peculiar 
"shot 'Mike  effect  when  hand  is  elevated  above  head. 
Visible  pulsation  in  all  superficial  arteries  of  any  size. 
Lungs  at  right  apex,  markedly  exaggerated  voice  and 
breathing,  otherwise  breathing  is  feeble  everywhere  ;  sub- 
crepitant  riles  all  over  chest.  A  diagnosis  was  made  of 
aneurism  of  ascending  arch  of  aorta  with  aortic  insufficiency. 

The  patient  remained  in  the  hospital  for  about 
eight  months.  The  details  of  treatment  need  not  be 
^one  into.  Reliance  was  chiefly  placed  on  digitalis  and 
iodide  of  potash,  the  dosage  being  varied  from  time  to 
time  to  suit  the  requirements  of  the  case.  A  fortnight 
after  admission  he  began  to  have  bloody  sputa,  which  con- 
tinued for  some  rime  ;  later,  attacks  of  spasmodic  dysp- 
noea came  on,  which  were  promptly  relieved  by  small 
hypodermics  of  Magendie's  solution.  Ten  weeks  after 
admission  he  began  to  have  nocturnal  dyspnoea,  with  angi- 
noid  paun  in  praecordium  and  left  shoulder,  running  down 
arm  to  elbow.  These  attacks  were  sometimes  cut  short 
bf  inhalations  of  amyl  nitrite,  and  later  by  internal  exhi- 
bition of  one  drop  of  a  one  per  cent,  solution  of  nitro- 
glycerine.    At  other  times  these  remedies  seemed  to  have 


no  effect  whatever.  A  month  later  the  arm  pain  was  ac- 
companied by  temporary  paralysis  of  entire  extremity. 
Four  months  after  admission  a  marked  thrill  and  visible 
pulsation  were  noted  in  carotids  and  over  sternum. 

The  patient  was  discharged,  improved,  on  April  6, 
1882.  During  preceding  two  months  had  had  only  two 
dyspnoeal  atUcks.  The  severity  of  all  the  symptoms  was 
greatly  abated,  though  the  physical  signs  remained  prac- 
tically the  same.  After  leaving  the  hospital  he  resumed 
work  as  an  iceman  and  passed  out  from  under  observa- 
tion. On  June  21,  1884,  he  again  presented  himself- 
having  enjoyed  fair  health  in  the  interim,  excepting 
that  the  cough  had  steadily  persisted.  Two  weeks  be- 
fore, he  caught  cold,  increasing  the  cough,  and  causing 
orthopnoea,  with  occasional  vomiting  after  couching 
severely.  He  had  scanty  muco-purulent  sputa,  pain  in 
right  chest,  anorexia,  with  cramps  in  belly  and  calves  of 
legs.  Cardiac  action  was  hurried,  averaging  120  per 
minute.  Respiration  40  and  very  labored ;  evening  tem- 
perature (mouth),  102.8°  ;  morning,  99.8°  ;  urine,  1.030, 
no  albumen,  but  hyaline  and  epithelial  casts.  Contrast- 
ing his  present  physical  condition  with  that  twenty-two 
months  ago,  the  following  points  of  difference  were 
noted :  The  heart-apex  was  in  sixth  space,  three  inches 
below  the  nipple  and  five  in  left  of  mid-sternal  line.  On 
level  of  the  third  rib  dulness  extended  from  half  an 
inch  to  the  right  of  sternum  to  one  inch  outside  left 
nipple.  The  area  of  dulness  in  the  right  upper  inter- 
spaces had  extended  to  third  space,  and  over  it  was  a 
visible  pulsation  with  marked  purring  systolic  thrill  and 
rasping  bruit;  the  finger  placed  in  supra-sternal  notch 
received  a  distinct  lift  at  each  cardiac  pulsation ;  there 
was  a  general  bulging  forward  of  the  entire  chest .  The 
appearance  of  a  localized  pulsation  over  the  area  of  dul- 
ness in  the  right  spaces  was  considered  as  verification  of 
the  previous  diagnosis.  He  was  ordered  milk  diet  with 
ten  grains  of  iodide  of  potash  ti.d.  His  dyspnoea  con- 
tinued, but  was  quite  well  controlled  by  small  doses  of 
opium.  On  June  24th  had  profuse  sweating  with  some 
dysuria.  Next  day  anginoid  pain  in  abdomen  returned,  but 
was  quieted  by  six  minims  of  Magendie  hypodermically. 
Early  on  the  morning  of  the  27th,  while  sitting  on  the 
side  of  the  bed  in  the  act  of  voiding  urine,  suddenly 
he  slid  down  to  the  floor,  grew  cyanotic,  radial  pulse 
ceased,  respiration  became  shallow,  and  ten  minutes 
later  he  quietly  died. 

The  autopsy  was  held  eight  hours  after  death,  by  Dr. 
J.  West  Roosevelt,  curator  to  the  hospital  No  aneurism 
was  found,  though  there  was  general  vascular  dilatation 
in  the  neighborhood  of  the  heart ;  the  latter  organ  weighed, 
free  of  dots,  thirty4wo  ounces ;  there  was  general  di- 
latation, the  walls  being  of  about  normal  thickness. 
The  aortic  valve  was  stenosed,  thickened,  and  insufficient, 
one  cusp  being  entirely  gone.  The  right  auricle  lay 
against  the  chest-wall  to  the  right  of  the  sternum,  behind 
the  first,  second,  and  third  ribs.  The  mitral  valve  was 
thickened,  but  seemed  sufficient,  as  did  also  the  valves  of 
the  right  heart  The  liver  was  hard,  firm,  and  con- 
gested, the  upper  part  of  the  right  lobe  showing  a  distinct 
depression  where  the  heart  had  rested.  The  kidneys 
were  firm,  of  normal  size ;  cortex  somewhat  thinned ; 
markings  distinct;  capsule  not  adherent;  chronic  con^ 
gestion.  Both  lungs  were  in  a  state  of  pigment  indura- 
tion. The  other  points  of  the  autopsy  call  for  no  special 
remark. 

A  consideration  of  the  physical  condition  and  situation 
of  the  heart  at  once  accounts  for  the  mistake  in  diagnosis. 
The  enormously  dilated  right  auricle,  lying  just  behind 
the  ribs,  gave  the  percussion  dulness,  and  through  its 
contents  received  the  direct  transmission  of  the  general 
impulse  occasioned  by  every  systole  of  this  veritable  "  cor 
bovinum."  To  the  eye,  ear,  and  finger  the  sensations 
were  those  of  a  true  aneurismal  sac.  Cases  of  this  nature 
are  unusual,  at  least  to  such  a  degree  as  was  manifested 
here.  The  weight  of  the  heart  is  by  far  the  largest  which 
the  pathological  records  of  this  hospital  show. 


264 


THE   MEDICAL  RECORD. 


[September  6,  1884- 


NEW  YORK  HOSPITAL. 

Report  of  the  Case  of  Yellow  Fever  in  New  York. 

By  FRANCIS  M.  D WIGHT,  M.D., 

MOUSB  rHYSiaAH. 

No  history  of  the  case  was  obtainable  previous  to  ad- 
mission at  10.30  P.M.,  August  29thy  when  temperature 
was  100.2°  ;  respiration,  30  ;  pulse,  100,  weak  and  irreg- 
ular. The  patient  was  well  nourished,  and  there  was  no 
oedema.  The  skin  was  intensely  jaundiced.  The  con- 
junctivae were  injected.  The  pupils  were  slightly  con- 
tracted There  was  marked  nystagmus,  general  cu- 
taneous hypersesthesia,  and  exaggerated  reflexes. 

Physictd  examination  showed  slight  dulness  over  both 
chests  posteriorlv.  Respiration  in  places  was  tubular 
and  accompaniea  with  fine  moist  r&les.  Voice  could  not 
be  obtained.  Cardiac  sounds  were  inaudible.  Palpa- 
tion over  the  abdomen  irritated  the  patient  very  much, 
and  apparently  caused  pain.  Examination  of  the  urine 
showed  its  specific  gravity  to  be  1,018,  acid  in  reaction, 
dark  yellow  in  color,  with  about  ten  per  cent  by  volume 
of  albumen. 

^  Digitalus  was  administered  hypodermically.  Shortly 
after  admission  the  patient  had  projectile  vomiting.  The 
vomited  matter  was  very  abundant ;  was  entirely  fluid, 
and  of  the  color  of  claret.  Microscopic  examination 
showed  it  to  contain  immense  numbers  of  partly  decom- 
posed blood-cells,  free  nuclei,  and  epithelial  detritus. 

The  patient  did  not  respond  at  all  to  stimulation.  Dur- 
ing the  night  he  was  restless  and  irritable,  vomiting  at 
intervals  of  two  or  three  hours.  At  3  A.M.,  temperature 
was  101.6°  F. ;  respiration,  24;  pulse,  100.  Two  hours 
later  the  patient  died.  The  temperature  taken  imme- 
diately after  death  was  105°. 

The  autopsy  was  conducted  by  Dr.  George  L.  Pea- 
body,  and  gave  the  following  results :  Body  was  well 
nourished,  deeply  jaundiced,  and  rigor  mortis  was  well 
marked.  There  was  no  oedema.  The  brain  and  mem- 
branes were  normal.  The  peritoneal  cavity  contained  no 
fluid;  there  was  no  peritonitis.  The  diaphragm  was 
normal  There  were  no  pleural  adhesions.  The  heart  was 
normal  in  size,  and  bright  yellow  in  color.  The  endo- 
cardium and  aorta  were  deeply  jaundiced.  The  valves 
were  competent  The  muscular  tissue  was  pale,  yellow, 
soft,  friable,  and  contained  an  abundance  of  fat  The 
lungs  contained  countless  hemorrhages,  varying  in  size 
from  that  of  a  small  pea  to  a  small  diestnut^  and  occur- 
ring all  through  the  parenchyma.  The  lungs  elsewhere 
were  intensely  congested  and  oedematous.  The  spleen 
was  about  three  or  four  times  the  size  of  a  normal  spleen, 
was  dark  in  color  and  somewhat  soft.  The  kidneys 
were  normal  in  size  and  very  yellow.  The  capsules  were 
not  adherent,  the  surface  was  smooth,  and  the  markings 
distinct     The  cortex  was  somewhat  swollen. 

The  stomach  contained  nearly  a  pint  of  fluid,  which 
was  largely  composed  of  dark-colored  blood.  The  mu- 
cous membrane  was  congested  and  covered  with  mucus. 
Near  the  pylorus  there  was  some  thickening  of  the 
mucous  membrane.  There  was  no  ulceration.  The 
duodenum  and  upper  part  of  the  jejunum  were  con- 
gested and  the  mucous  membrane  somewhat  swollen. 
The  common  bile-duct  was  pervious.  The  intestines 
throughout  contained  a  large  amount  of  blood,  some  of 
which  was  fluid  and  some  &ck,  dark,  and  tarry  in  color 
and  consistence.  No  ulcers  were  found.  The  liver  was 
normal  in  size.  The  cut  surface  was  mottled  and  pre- 
sented areas,  apparently  peripheral,  of  brilliant  red  color 
with  pale  yellowish  centres  of  acini  which  were  deeply 
jaundiced  and  contained  fat  The  galUbladder  contained 
a  small  amount  of  dark  thick  bile. 

Microscopic  Examination. — Heart :  Abundance  of  fat 
was  found,  both  in  the  form  of  granules  and  of  small 
drops,  and  to  such  an  extent  in  many  places  as  to  ob- 
scure the  transverse  striae.     Kidneys:    There  was  an 


abundance  of  granular  fat  and  drops  of  fat  in  the  epithe- 
lium of  the  straight  and  convoluted  tubes.  Elsewhere 
the  epithelium  appeared  swollen  and  clouded.  Liver : 
There  was  much  extravasated  blood  and  imbibition  of 
blood  coloring  matter  in  the  peripheries  of  the  acini ;  at 
the  centres  the  cells  contained  an  abundance  of  fat 


"^a^^z&i^  0t  ptiedical  jlctence. 


Cachectic  Purpura. — According  to  the  opinion  of 
Dr.  A.  Mathieu,  purpura  hemorrhagica  is  not  a  disease 
sui  generis,  but  is  merely  a  symptom  of  some  other  mor- 
bid condition.  He  proposes,  therefore,  to  group  together 
all  the  various  fonns  of  the  afiection  under  the  general 
name  oi  purpura  cacheciica^  of  which  he  recognizes  three 
groups.  The  first  comprises  the  various  forms  of  hem- 
orrhage occurring  in  pernicious  anaemia.  In  the  second 
group  the  purpura  appears  in  the  subjects  of  tuberculosis. 
The  nervous  system  plays  here  an  important  rdle,  so  that 
the  afiection  has  been  called  by  some  purpura  ncuro- 
pathica  or  myelopathica.  The  hemorrhages  occurring  in 
the  third  division  are  occasioned  by  the  cachexia  of 
Bright*  s  disease.  They  are  a  symptom  as  frequently  met 
with  as  oedema.  A  special  form  of  cachectic  purpura, 
and  one  which  is  closely  allied  to  that  of  Bri^ht's  disease, 
is  senile  purpura.  Atheroma  of  the  arteries  is  a  very  im- 
portant factor  in  the  etiology  of  this  variety.  This  form 
of  purpura  is  characterized  by  its  long  duration,  its  pecu- 
liar seat,  occurring  as  it  does  often  on  the  dorsal  surfaces 
of  the  hands  and  feet,  and  on  the  ulnar  side  of  the  fore- 
arm, and  by  the  shape  of  the  petechiae  which  are  small, 
lenticular,  and  without  any  areola.  It  is  also  worthy  df 
note  that  the  red  globules  in  this  form  of  purpura,  as  was 
demonstrated  by  Hayem,  are  normal  in  function  and  pos- 
sess the  proper  amount  of  haemoglobin.  The  author 
sums  up  the  results  of  his  investigations  as  follows :  l 
Cachectic  purpura  appears  in  the  form  of  petechiae  and 
of  ecchymoses ;  the  first  are  either  pilo  -  sebaceous  or 
cutaneous,  the  latter  may  be  very  extensive  in  area.  The 
papular  and  erythematous  forms  are  never  seen  in  this 
variety  of  purpura.  2.  The  first  group,  that  of  excessive 
anaemia,  is  characterized  by  the  firequency  of  oedema 
and  hemorrhage.  In  this  group  may  be  included  pur- 
pura of  the  cancerous  cachexia  and  of  the  anaemia  of 
miners.  3.  In  tuberculosis  the  purpuric  eruption  is  caused 
by  the  secondary  afiections,  such  as  menin^tis,  albumi- 
nuria, diseases  of  the  liver,  etc  4.  Purpura  is  a  very  fre- 
quent phenomenon  in  Bright's  disease,  and  is  to  be  re- 
garded as  of  evil  prognostic  import,  as  it  is  generally  the 
forerunner  of  uraemia  and  death.  5.  In  the  cachexia  of 
heart  disease  purpura  may  be  induced  by  a  variety  of 
causes,  such  as  albuminuria,  pernicious  jaundice,  arterial 
sclerosis,  oedema,  and  embolism. — Schmidt s  JahrhiUhcr^ 
May  20,  1884. 

The  Value  as  a  Symptom  of  the  Swashing  Sound 
IN  THE  Stomach. — Chomel  regarded  this  sound  as  a 
characteristic  sign  of  a  morbid  condition  which  he  called 
indigestion  of  fluids.  He  believed  that  the  stomach  was  in- 
capable of  absorbing  or  of  passing  into  the  duodenum  the 
ingested  liquids  or  those  secreted  within  the  organ  itselil 
These  liquids  accordingly  accumulated  within  the  stom- 
ach, and  their  presence  was  manifested  by  a  succussion 
sound  on  shaking  the  patient  He  considered  this  sound 
to  be  always  a  pathological  phenomenon.'  These  views 
were  controverted  by  M.  Andhoui  in  a  note  presented  to 
the  Paris  Academy  of  Science  (Z'  Union  MidicaU^  July 
12,  1884).  He  had  made  a  number  of  experiments  upon 
dyspeptic  and  healthy  individuals,  and  had  found  the 
succussion  sound  always  present  immediately  after  the 
ingestion  of  a  quantity  of  fluid.  He  concluded,  there- 
fore, that  Chomel  was  wron^  in  believing  it  to  be  a  path- 
ognomonic sign  of  indigestion  of  fluids,  or  of  any  other 
gastric  disorder. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


265 


Polyuria  in  Convalescence  from  Typhoid  Fever. 
^The  attention  of  Dr.  Spitz  having  been  attracted  by 
the  case  of  a  convalescent  from  typhoid  fever,  who 
^passed  from  three  to  four  quarts  of  urine  a  day,  he  was  led 
to  study  the  subject  more  closely.  He  found,  to  his  great 
astonishment,  that  polyuria,  sometimes  to  a  remarkable 
degree,  was  present  in  about  half  the  cases  of  convales- 
cence from  tjTphoid.  The  amount  of  urine  excreted  was 
usually  greater  as  the  fever  itself  had  been  more  severe. 
The  urine  is  of  a  light  yellow  color,  transparent,  without 
sugar  or  albumen,  and  forming  no  special  deposit.  Its 
q)ecific  gravity  varies  inversely  to  the  total  amount  ex- 
creted during  the  twenty-four  hours.  The  polyuria  be- 
gins at  the  period  of  greatest  oscillations  of  temperature 
and  persists  up  to  the  fifth  or  sixth  week  of  convales- 
cence. It  would  seem  to  be  of  favorable  prognostic  in»- 
port — L  Union  M^dicaic,  July  6,  1884. 

Hypodermic  Injections  of  Quinine  in  the  Dif- 
ferentiation OF  Malarlal  from  Typhoid  Fever. — Dr. 
Aimibale  ArzeU  employs  quinine  subcutaneously  in  doses 
of  fifteen  grains  and  more,  according  to  the  age  and  con- 
stitution of  the  patient,  as  a  means  of  diagnosis  between 
remittent  and  typhoid  fever.  If  the  disease  be  malarial 
in  origin,  soon  after  the  injection  a  noticeable  depression 
occurs  in  the  temperature  curve,  which  eventuates  the 
next  day,  perhaps  after  another  dose  of  quinine,  in  com- 
plete apyrexia.  If  the  affection  be  typhoid  fever  the  fall 
in  temperature  is  merely  temporary.  It  is  necessary  to 
give  the  quinine  subcutaneously,  as  the  intestinal  mucous 
membrane  is  in  such  a  condition  that  absorption  of 
remedies  administered  per  orem  may  not  occur. — Deutsche 
Medicinal-Zeitungy  vol  v..  No.  50,  1884. 

Treatment  of  Fractured  Patella. — Dr.  Van  der 
Meulen  notes  that  in  the  space  between  the  two  frag- 
ments of  a  broken  patella,  a  clot  of  blood  is  formed. 
This  clot  is  not  organized  at  once  in  its  entirety,  but  the 
anterior  and  posterior  surfaces  are  first  organized,  and 
only  after  some  time  does  the  process  involve  the  cen- 
tial  portion.  In  this  way  the  two  fragments  come  to  be 
united  by  two  thin  pseudo-membranes.  The  author 
takes  advantage  of  this  in  his  treatment  of  fractured 
patella.  From  ten  to  twenty  days  after  the  injury  he  pro- 
ceeds to  operate.  An  incision  being  made  over  the 
patella,  the  anterior  membrane  and  the  unorganized 
coaguluml3ring  beneath  it  are  removed,  but  the  posterior 
membrane  is  not  interfered  with,  and  thus  the  joint  is  not 
opened.  The  fragments  are  then  united  by  platinum  or 
alver  wire  suture,  care  being  taken  not  to  include  the 
inembrane  of  organized  coagulum,  but  to  let  it  fold  upon 
itself  posteriorly  toward  the  joint  cavity.  Dr.  Van  der 
Meulen  has  operated  in  this  manner  in  three  cases  of 
fractured  patella,  and  has  been  enabled  to  obtain  ex- 
cellent and  firm  union. — Deutsche  Medicinal^Zeitung^ 
July  21,  1884. 

The  Diagnosis  of  Sclatica. — M.  de  Beurmann 
advises,  in  any  case  where  there  is  a  question  of  dia^osis 
between  sciatica  and  any  other  painful  affection  in  the 
region  of  the  hip,  that  the  patient  be  placed  on  the  back 
and  then,  the  knee  being  held  in  complete  extension, 
flexion  be  made  of  the  thigh  upon  the  trunk.  When  this 
is  done,  the  patient  at  once  complains  of  severe  pain  in 
the  buttock  at  the  point  corresponding  to  the  sciatic 
notch.  If  now  the  knee  be  flexed,  no  pain  is  experi- 
enced upon  flexion  of  the  hip.  According  to  Las^gue 
this  pain  is  caused  by  compression  of  the  nerve  by  the 
surrounding  muscles,  but  De  Beurmann  shows  that  it 
IS  due  rather  to  stretching  of  the  nerve  trunk  by  the  con- 
strained position  of  the  limb.  This  sign,  more  valuable 
than  that  of  Valleix's  tender  points,  is,  the  writer  states, 
constantly  present.  It  is  moreover  characteristic,  for  in 
other  affections  simulating  sciatica  the  presence  or 
absence  of  pain  is  not  dependent  upon  the  tension  or  re- 
laxation of  the  nerve,  consequent'  upon  the  varying  posi- 
tions of  flexion  and  extension  of  the  knee. — La  France 
MUicale^  August  2,  1884. 


Treatment  of  Locomotor  Ataxla. — Dr.  Mtiller 
claims  to  have  had  a  measure  of  success  in  his  treatment 
of  this  aflection.  The  diet,  he  says,  should  be  strengthen- 
ing. Coffee,  strong  tea,  and  undiluted  alcoholic  bever- 
ages are  forbidden.  In  the  medicinal  treatment  a  pill  is 
used  composed  of  ^^  grain  of  nitrate  of  silver  and  i^ 
grain  of  extract  of  ergot.  The  dose  is  one  pill  three 
times  a  day,  and  is  gradually  increased  to  three  pills  three 
times  a  day.  After  about  twenty  grains  of  nitrate  of 
silver  have  been  taken,  the  pills  are  discontinued  for  three 
weeks,  when  their  administration  is  then  resumed  in  the 
same  way.  The  treatment  may  extend  over  five  or  six 
months.  The  author  does  not  believe  that  the  disease 
is  often  of  syphilitic  origin,  aY)d  never  uses  specific  treat- 
ment unless  he  can  discover  unmistakable  evidences  of 
syphilis.  Electricity  is  often  useful,  but  galvanization  of 
the  medulla  should  be  practised  as  'weU  as  that  of  the 
cord.  Faradization  of  the  skin  by  means  of  the  brush 
electrode,  either  alone  or  combined  with  galvanization  of 
the  nervous  centres,  may  also  be  of  advantage.  The 
author  condemns  hot  water  or  vapor  baths  as  bein^  posi- 
tively injurious.  Cold  baths  are  also  contra-indicated. 
The  proper  temperature  for  a  bath  is  84°  to  86®,  and  the 
patient  should  remain  in  the  water  for  fit>m  three  to  five 
minutes  only.  Massage  may  prove  to  be  of  use,  though 
data  on  this  point  are  wanting.  Stretching  of  the  longer 
nerve-trunks  is  a  dangerous  and  unwarranted  procedure. 
For  the  pains  Dr.  Miiller  makes  local  applications  of  a 
liniment  consisting  of  veratria,  four  grains  ;  chloroform, 
half  an  ounce  ;  and  oil,  one  ounce.  For  the  gastralgic 
crises  he  uses  strong  faradization  with  a  brush  over  the 
epigastriuuL  Ocuku-  paralysis  is  treated  by  the  continued 
current  For  the  relief  of  vesical  spasm,  he  gives  pills 
containing  one  and  a  half  grain  of  the  extract  of  cannabis 
indica. — La  France  Medicale^  July  31,  1884. 

The  Weight  of  the  Heart  in  Cancerous  Affec- 
tions OF  THE  Uterus. — It  has  been  stated  by  Dr. 
Artaud  that  the  heart  is  hypertrophied  in  cases  of  car- 
cinoma of  the  uterus,  in  consequence  of  secondary  in- 
flammation of  the  kidneys.  In  a  series  of  post-mortem 
observations  made  to  verify  this  assertion  {Le  Progrls 
M^icaly  August  2,  1884),  Drs.  F6r^  and  Quermonne 
found  that  such  was  not  the  case.  As  the  result  of  their 
investigations  they  conclude  that,  not  only  is  hypertrophy 
of  the  heart  not  the  rule  in  those  suffering  from  renal 
lesions  consequent  upon  cancer  of  the  uterus,  but  that 
on  the  contrary,  the  heart,  as  is  usually  the  case  in  can- 
cerous subjects,  whatever  the  seat  of  Uie  lesion,  is  more 
or  less  atrophied. 

A  Case  of  Acttte  Iodism. — A  gentleman  in  perfect 
health  took  a  dose  of  fifteen  grains  of  iodide  of  potassium 
in  the  hope  of  overcoming  the  disgust  felt  for  it  by  his 
wife,  for  whom  the  drug  had  been  prescribed.  This  oc- 
curred about  six  o'clock  in  the  evening,  and  no  evil  effects 
were  experienced  until  eleven  o'clock,  after  he  had  re- 
tired. He  was  then  suddenly  awakened  by  violent  sneez- 
ing accompanied  by  excruciating  pain  in  the  upper  jaw. 
This  was  so  severe  as  to  drive  the  patient  nearly  frantic. 
The  upper  part  of  the  face  was  somewhat  swollen,  and 
nasal  respiration  was  impeded,  though  there  was  no  dis- 
charge from  the  nostrils.  The  eyes  were  sufiiised  with- 
out there  being  an  actual  flow  of  tears.  There  was  also 
some  nausea  and  vomiting.  M.  L^ger,  who  was  sum- 
moned about  four  o'clock,  found  the  patient  still  suffer- 
ing from  constant  pain,  with  exacerbations  every  few 
minutes,  in  the  upper  jaw  and  the  teeth.  This  pain  was 
not  increased  by  pressure  upon  the  infra-orbital  nerves. 
The  symptoms  pointed  to  inflammation  of  the  mucous 
membrane  lining  the  two  antra,  but  no  cause  could  be 
found  to  account  for  its  sudden  onset,  until  the  patient 
mentioned  casually  that  he  had  taken  a  dose  of  his  wife's 
medicine.  The  symptoms  continued  with  but  slight 
abatement  until  the  following  evening,  and  then  slowly 
disappeared,  leaving  no  sequelae. — Journal  de  Midecine 
et  de  Chirurgie  Pratiques^  July,  1884. 


^66 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


Borax  in  the  Treatment  of  Contagious  Diseases. 
— In  a  communication  made  to  the  Academic  des 
Sciences  {L  Union  MidiccUe^  August  2,  1884)^  Dr.  de 
Cyon  urges  upon  the  members  the  employment  of  borax 
as  an  internal  disinfectant.  It  is,  he  asserts,  perfectly 
innocuous  to  the  human  organism,  even  when  taken  in 
quantities  of  half  an  ounce  or  more  per  diem.  He  op- 
poses the  notion  that  a  microbidde  is  the  more  effectual 
in  proportion  as  it  is  the  more  poisonous  to  man.  The 
efficacy  of  this  substance  as  a  prophylactic  against  cholera 
was  demonstrated,  the  author  says,  during  the  cholera 
epidemic  which  ravaged  Italy  in  1865.  At  that  time  not 
one  of  the  workmen  employed  in  the  seven  boracic  acid 
factories  at  Larderello  was  attacked,  while  in  a  village 
scarcely  two  miles  distant  one-third  of  the  inhabitants 
died  from  cholera.  Taken  in  quantities  of  seventy- 
five  to  ninety  grains  per  diem,  the  borax  would  not  only 
exert  a  direct  action  upon  the  microbes  in  the  intestinal 
canaly  but  would  be  taken  into  the  blood  and  destroy  the 
organisms  there  present  The  constipating  effect  of 
borax  would  be  another  indication  as  regards  cholera. 
He  recommends  that  those  exposed  to  cholera  should 
wash  the  mucous  membranes  frequently  with  a  solution 
of  boracic  acid  or  borax,  and  also  take  about  ninety 
grains  of  borax  internally  each  day. 

The  Induced  Current  in  the  Treatment  of 
PLEURinc  Effusions. — Dr.  Giuseppe  Manzini  has  col- 
lected a  number  of  cases  of  absorption  of  the  fluid  in 
chronic  pleurisy  after  the  persevering  use  of  the  induced 
current  applied  to  the  thoracic  wall  In  a  few  instances 
there  was  at  first  a  little  fever  and  a  slight  degree  of  in- 
flammation, induced  apparently  by  irritation  from  the 
electricity.  Although  these  cases  also  terminated  favor- 
ably, the  author  advises  that  the  treatment  be  not  under- 
taken until  every  trace  of  inflammatory  action  has  sub- 
sided. The  action  of  electricity  in  causing  absorption  is 
explained  :  i,  by  the  increased  power  of  contraction  in 
the  intercostal  muscles  and  diaphragm,  previously  weak- 
ened by  the  hypersemia  and  oedema,  which  contraction 
exerts  a  pressure  upon  the  fluid  contained  in  the  thora- 
cic cavity;  2,  by  strong  irritation  of  the  vasomotor 
nerves,  which  restores  to  the  tissues  their  absorbing 
power. — Deutsche  MedicincU-Zeitung^  July  10,  1884. 

Malaria  and  Osteopathies. — Dr.  Barberi-Boughini, 
in  an  article  on  this  subject,  notes  the  anatomical  and 
physiological  relations  between  the  spleen  and  the  medul- 
lary substance  of  the  bones,  and  concludes  that  it  is 
reasonable  to  suppose  that  when  the  former  is  affected  by 
the  malarial  infection  the  latter  is  also  involved.  He 
calls  attention  to  the  frequency  of  non-union  or  slow 
union  of  fractures  in  malarious  subjects,  and  mentions 
several  instances  in  which  he  found  meUmotic  disease  of 
the  medulla  of  one  or  more  of  the  long  bones  in  cases  of 
'  h)rpertrophied  spleen  from  malaria.  He  concludes  that : 
I.  We  should  recognize  the  existence  of  leucocythaemia 
due  to  changes  in  the  various  bones.  2.  The  malarial 
poison  may  act  by  itself  in  inducing  these  changes,  or 
may  be  a  most  powerful  coefficient  to  the  expression  of 
other  diatheses  not  yet  determined.  3.  Malaria  ought 
therefore  to  be  regarded  as  a  cause  of  various  osteo- 
pathies.— Rivista  Clinica^  July,  1884. 

The  Condition  of  the  Blood  in  Hydrophobia. — 
In  an  examination  of  the  blood  drawn  rapidly  from  the 
vessels,  especially  from  the  sinuses  of  the  dura  mater.  Dr. 
Romiti  {Rivista  Clinica,  July,  1884)  found  it  to  be  of  a 
dark  red  color  and  not  coagulable  spontaneously.  The 
red  globules  were  rather  pale,  and  when  the  preparation 
was  stained  by  Bizzozero's  method,  and  placed  under  an 
immersion  lens,  there  appeared  a  mass  of  granular  matter 
in  which  the  white  globules  seemed  to  be  imbedded. 
These  appearances  were  similar  to  those  presented  by 
the  blood  of  persons  killed  by  snake  bites. 

The  Functions  of  the  Thyroid  Gland. — In  an 
article  in  the  Archivio  per  le  Scienze  Mediche^  vol.  viii.. 


No.  lOy  1884,  Drs.  Sanquirico  and  Canalis  describe  a 
number  of  experiments  made  by  them  to  determine  the 
function  of  the  thyroid  gland  and  its  value  to  the  economy. 
From  the  results  of  these  experiments  the  authors  draw 
the  following  deductions:  i.  The  extirpation  of  the 
entire  thyroid  gland  in  dogs  is  fatal,  whether  the  spleen 
have  previously  been  removed  or  not  2.  Dogs  from 
whom  the  spleen  has  been  taken  away  bear  incomplete 
thyroidectomy  without  any  apparent  ill  effects.  3.  There 
is  no  functional  relationship  between  the  thyroid  gland 
and  the  spleen.  4.  Only  a  small  portion  of  the  thyroid 
requires  to  be  spared  in  order  that  the  functions  proper 
to  this  gland  may  be  actively  performed  and  that  there 
may  be  no  change  in  the  animal's  general  condition; 
though  not  yet  positively  determined,  it  would  appear 
that  the  upper  part  of  the  gland  is  the  part  that  must  be 
spared  in  order  not  to  interfere  with  its  necessary  func- 
tions. 5.  The  fatal  results  following  complete  thyroidec- 
tomy cannot  be  referred  to  quantitative  changes  in  the 
elements  of  the  blood,  for  the  changes  observed  were 
neither  constant  nor  of  sufficient  gravity.  6.  Although 
the  experiments  thus  far  made  have  not  demonstrated 
what  the  functions  of  this  gland  are,  they  are  yet  sufficient 
to  exclude  the  notion  of  a  haematogenetic  action,  and 
therefore  to  prove  that  the  thyroid  cannot,  in  this  respect 
at  least,  be  a  substitute  for  the  spleen.  Nevertheless  we 
are  justified  in  assuming  that  it  has  an  important  action 
upon  the  animal,  and  m  all  probability  in  relation  with 
the  nervous  centres.  The  authors  have  never  met  with 
an  absence  of  the  thyroid  gland  in  any  of  the  animals 
examined  by  them,  although  Tauberhas  asserted  that  the 
organ  is  quite  frequently  wanting  in  the  domestic  animals. 

Sub-clavicular  Tympanic  Resonance  in  Pneumo- 
nia.— In  a  soldier  suffering  from  acute  double  pneumo- 
nia, Dr.  Lav6ran  {JO  Union  M^dicale^  No.  55, 1884)  found 
a  tympanic  resonance  under  the  left  clavicle.  This 
resonance  persisted  from  the  third  day  of  the  disease 
until  the  patient's  death.  At  the  autopsy  the  lef^  lung 
was  found  to  be  throughout  in  a  state  of  gray  hepatization. 
Not  being  able  in  this  case  to  admit  the  theory  of  Skoda 
and  others,  who  explain  this  phenomenon  by  the  integrity 
of  the  corresponding  portion  of  the  other  lung,  Dr.  La- 
v6ran  concluded  that  the  resonance  was  that  of  the 
trachea  and  larger  bronchi  transmitted  through  the  solid- 
ified lung-tissue. 

Purulent  CoNjuNcrivrris. — In  a  considerable  num- 
ber of  cases  of  purulent  ophthalmia  Dr.  Johan  Widmark 
{Hygieay  No.  6,  1884])  was  able  to  demonstrate  the 
presence  of  gonococci.  The  micro-organisms  were 
generally  found  in  the  wandering  cells,  though  they  were 
also  present  in  the  secretion.  In  some  cases  of  con- 
junctivitis of  the  new-bom  the  author  discovered  the 
cocci  in  the  epithelial  cells.  In  one  case  also  of  oph- 
thalmia in  the  adult  they  were  present  in  the  epithelial 
cells  in  the  first  days  of  the  disease,  but  disappeared  on 
the  third  day.  The  author  concludes  from  this  that,  as 
is  asserted  by  Welander  to  be  the  case  in  gonorrhoea,  the 
gonococci  are  developed  in  the  epithelium,  and  only 
later  penetrate  into  the  subjacent  tissues.  In  every  case 
Dr.  Widmark  was  able  to  prove  contagion,  in  adults, 
from  the  presence  of  the  gonococci  in  the  antecedent 
urethral  discharge,  and  in  the  new-bom  firom  the  pres- 
ence of  these  organisms  in  the  vaginal  secretions  of  the 
mother.  The  results  of  treatment  in  the  new-bom  were 
excellent,  but  the  disease  in  the  adult  was  very  intract- 
able. This  difference  the  author  explains  by  the  state- 
ment that  in  the  adult  there  is  a  layer  of  adenoid  tissue 
beneath  the  conjunctiva  which  is  wanting  in  the  infant 
The  micro-organisms  have  a  predilection  for  all  glandular 
stmctures,  and  therefore  pass  deeply  down  into  this  sub* 
conjunctival  layer  out  of  the  reach  of  local  applications* 
In  the  treatment  Dr.  Widmark  makes  a  strong  applica- 
tion of  nitrate  of  silver  once  a  day,  and  washes  the  eye 
frequently  with  solutions  of  boracic  acid  and  of  corrosive 
sublimate  (jirhnr)  employed  altemately. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


267 


The  Medical  Record 


A  Weekly  journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Ptjblishsd  by 
WM.  WOOD  &.  Co..  Nos.  56  and  58  Ufayette  Place. 

New  York,  Septemberv  6,  1884. 

CHOLERA  AND  THE  COMMA-BACILLUS. 

A  VERY  interesting  lecture  on  cholera,  an  abstract  of 
which  is  given  in  this  and  the  preceding  issue  of  Thb 
Rkcord,  was  delivered  recently  by  Dr.  Koch  before  an 
assembly  of  prominent  physicians  and  hygienists  in  Berlin. 
The  speaker  described  the  minute  organism  discovered 
by  him  in  the  intestinal  discharges  of  cholera  patients, 
and  which  he  maintains  is  the  actual  cause  and  essence 
of  the  disease.  This  organism  has  been  called  rather 
inaptly  the  comma-bacillus,  although  it  resembles  a 
mark  of  parenthesis  more  than  it  does  a  comma,  and  is 
probably  a  spirillum  and  not  a  bacillus.  Dr.  Koch  makes 
oat  a  very  strong  point  in  favor  of  the  bacillus  theory  of 
cholera  and  of  his  claim  to  have  discovered  the  special 
miao-organism  that  causes  the  disease.  He  found  the 
commapbacillus  in  every  one  of  nearly  a  hundred  cases 
of  Asiatic  cholera,  while  its  presence  could  not  be  de- 
tected in  cases  of  cholera  morbus  and  other  diseases  in 
which  a  search  was  made.  Nevertheless  it  would  be 
rash  to  assert  that  it  is  not  present  in  any  other  disease, 
and  it  may  yet  be  found  in  other  afifections,  just  as  Fried- 
lander's  pneumonic  cocci  are  said  to  have  been  detected 
in  inflamed  tissues  other  than  the  lungs.  Indeed,  Dr. 
Klein,  a  London  physician,  has  recently  asserted  that  he 
found  micro-organisms,  indistinguishable  from  the  comma- 
badlli,  in  the  discharges  of  patients  suffering  from  a 
diarrhoea  which  was  epidemic  in  Cornwall  in  1883.  As 
he  made  no  culture  tests,  however,  his  statements  can- 
not be  accepted  as  conclusive.  And  more  than  this,  the 
crucial  test  of  a  theory  of  this  kind  is  wanting,  namely, 
inoculation  by  the  infectious  material.  Various  attempts 
have  been  made  to  induce  cholera  in  the  lower  animals 
by  feeding  them  with  matters  containing  the  comma- 
badlli,  but  always  without  success.  Koch  says  that 
animals  enjoy  a  special  immunity  against  the  disease ; 
but  while  this  may  be  a  sufficient  explanation  of  the 
failure  of  these  experiments,  it  nevertheless  leaves  the 
main  question  of  inoculability  untouched. 

Although  it  would  be  premature  without  further  evi- 
dence to  regard  the  problem  of  the  cause  of  cholera  as 
ahready  solved,  the  possibility  of  Koch's  solution  being 
the  correct  one  is  nevertheless  so  great  that  it  may  not 
be  unprofitable  to  consider  some  of  the  sanitary  bearings 
of  his  theory. 

The  lecturer  stated  that  the  badllus  was  found  only  in 
toR  intestinal  canal  and  its  contents,  and  never  in  any  of 
the  other  organs  or  secretions  of  the  body.     Further  ' 


than  this,  it  was  only  in  the  lower  portion  of  the  digestive 
canal,  the  gastric  secretion,  when  normal  in  character, 
being  fatal  to  the  life  of  the  micro-organism.  This  point 
is  of  considerable  importance,  since,  as  the  bacillus  can 
gain  admission  only  through  the  mouth,  it  must  first  run 
the  gauntlet  of  the  stomach  before  it  can  reach  a  locality 
favorable  to  its  development.  Thus,  a  healthy  individual 
whose  gastric  secretions  are  normal  in  quantity  and 
quality,  is  far  less  likely  to  contract  the  disease  than  is  a 
dyspeptic.  This  might  explain  the  influence  of  fear  as  a 
predisposing  cause  of  cholera,  since  good  digestion  is  so 
dependent  upon  a  quiet  mind.  Hydrochloric  acid  and 
pepsine  may  yet  rank  high  among  the  preventives  of 
cholera. 

A  still  more  important  statement  was  that  the  bacillus 
is  absolutely  dependent  upon  moisture  for  its  life.  There 
is  no  stage  of  its  existence  during  which  it  may  remain 
dormant  for  an  indefinite  time,  ready  for  further  develop- 
ment and  reproduction  under  favoring  circumstances. 
Once  the  material  in  which  it  is  contained  be  thoroughly 
dried,  then  the  comma-badllus  is  dead  and  can  never 
be  resuscitated. 

If  this  be  so,  the  question  of  disinfection  becomes  a 
very  simple  one.  All  rags,  clothing,  or  personal  effects 
of  cholera  patients  need  but  to  be  carefully  dried,  and 
they  are  thenceforth  absolutely  incapable  of  carrying 
contagion.  In  the  same  way  letters  could  be  dried,  and 
the  absurd  precaution  of  enclosing  them  in  tarred  mail- 
bags  might  then  be  abandoned.  The  assertion  that  the 
infectious  material  of  cholera  cannot  be  carried  in  the 
air,  but  can  only  be  transmitted  to  distant  places  by 
persons  suffering  from  the  disease  or  by  articles  soiled 
with  choleraic  discharges,  will,  if  true,  lend  a  measure  of 
support  to  the  establishment  of  sanitary  cordons,  and 
demonstrate  the  utility  of  quarantine.  That  the  bacillus 
can  flourish  under  favoring  conditions  outside  of  the 
human  body,  is  amply  demonstrated  by  the  facts  of  culti- 
vation in  gelatine,  milk,  blood  serum,  potato,  and  other 
substances.  Impure  drinking-water  would  seem  to  be 
one  of  the  most  ordinary  channels  through  which  the 
contagion  of  cholera  is  introduced  into  the  intestinal 
tract.  Dr.  Koch  cited  numerous  striking  cases  showing 
the  value  of  pure  water  in  reducing  the  death-rate  from 
this  disease.  He  stated  also  that  the  comma^baciUus 
did  not  thrive  in  pure  water,  but  died  within  a  few  days. 
One  of  the  most  valuable  results  of  the  discovery  of  the 
cholera  bacillus,  even  though  it  be  proven  not  to  be  the 
real  cause  of  the  disease,  provided  only  that  it  be  pecu* 
liar  to  this  affection  and  not  present  in  any  other,  will  be 
the  facility  thus  afforded  to  a  certain  and  early  diagnosis. 
The  value  of  this  can  hardly  be  over-estimated,  for  the 
first  cases  usually  come  singly,  and  if  they  can  be  prompt- 
ly recognized  and  placed  under  surveillance  from  the 
very  beginning,  a  destructive  epidemic  may  be  warded  ofil 
Whereas,  if  the  first  few  days  be  spent  in  trying  to  decide 
what  the  nature  of  the  disease  is,  by  the  time  it  is  recog- 
nized to  be  cholera  it  may  be  too  late  to  check  its  ad- 
vance. Dr.  Koch  maintains  that  a  simple  microscopical 
examination  of  the  choleraic  discharges  is  not  always 
sufficient  to  base  a  diagnosis  upon,  but  that  by  the 
method  of  culture  absolute  certainty  may  be  obtained. 
He  looks  upon  this  as  a  very  simple  matter,  and  seems  to 
think  that  anybody  can  do  it     But  he  appears  to  be  a 


268 


THE  MEDICAL  RECORD. 


[September  6, 1884- 


little  over-sanguine  in  this  respect.  It  is  hardly  reason- 
able to  expect  that  every  physician  will  take  the  trouble, 
even  if  he  has  the  time  to  spare,  to  acquire  the  skill 
necessary  for  conducting  a  trustworthy  culture  of  the 
comma-bacillus.  But  practically,  in  cities  at  least,  such 
a  general  knowledge  of  bacteriology  is  not  necessary. 
The  investigation  of  doubtful  cases  could  be  entrusted  to 
the  sanitary  authorities,  as  is  done  now  in  other  contagious 
diseases. 

It  is  to  be  hoped  that  Koch  will  be  able  to  substantiate 
his  claims  clearly  and  beyond  dispute,  for  we  shall  then 
be  on  the  high  road  to  victory  over  this  dreaded  disease, 
and  cholera  will  take  its  place  alongside  of  small-pox  as 
one  of  the  former  scourges  of  the  human  race  from  which 
modem  civilization  has  little  to  fear. 


GASTRIC    HYSTERIA,    AND    THE   FASTING   GIRL   OF 
FORT  PLAIN. 

The  necessity  of  a  suitable  dietary  regimen  is  seen  in 
the  fact  that  man,  and  warm-blooded  animals  generally, 
cannot  survive  abstinence  from  food  longer  than  from 
seven  to  ten  days ;  the  period  may  be  somewhat  extended 
if  water  be  supplied,  and  it  may  be  very  much  prolonged 
if  a  minute  quantity  of  nutriment  be  taken  daily. 

Cold-blooded  animals  can  endure  fasting  for  a  consid- 
erably longer  time;  although  some  species  (notably  of 
fishes)  are  characterized  by  excessive  voracity,  and  all 
are  dependent  for  the  normal  performance  of  their  func* 
tions  on  regular  alimentation,  it  is  nevertheless  a  fact 
that  reptiles  and  amphibia  have  been  known  to  live  for 
many  months  without  any  food  whatever.  A  gentleman, 
for  whose  veracity  we  can  vouch,  has  reported  to  The 
Record  a  case  of  nine  months'  fasting  in  a  couple  of 
frogs ;  *  and  an  alligator  now  in  our  possession  has  for 
more  than  ninety  days  refused  all  sustenance.  Such 
warm-blooded  animals  as  hibernate  during  the  cold  sear 
son  are  examples  of  a  similar  kind  In  all  these  in- 
stances changed  conditions  in  the  environment  have 
caused  retardation — sl  quasi  stagnation  of  the  organic 
processes ;  assimilation  and  disassimilation  are  almost 
nil ;  animal  heat  is  scarcely  above  that  of  the  surround- 
ing medium ;  secretion  and  excretion  are  at  their  mini- 
mum. 

Although  all  active  manifestations  of  life  are  the  ex- 
pression of  change  in  the  protoplasmi  matter  of  life, 
necessitating  constant  waste  and  repair,  yet  there  are 
all  grades  of  vital  action  (and  concomitant  molecular 
change) ;  from  the  "  latent  life  "  of  spores  and  seeds  and 
grains,  of  dried  rotifers  and  tardigrades  and  certain  in- 
fusoria, which  are  capable  of  existing  for  years  in  a  state 
of  physical  and  chemical  torpor  without  maintaining  any 
relations  of  exchange  with  their  environment ;  to  the  in- 
stances already  given  of  'Mife  ¥dth  oscillations"  (the 
terms  are  those  of  M.  Claude  Bernard),  where  the  con- 
dition is  not  one  of  absolute  torpor  and  inertness,  but 
one  in  which  the  vital  manifestations  are  at  a  low  ebb ; 
to  finally — what  shall  we  take  as  our  highest  example  ? — 
to  the  indefatigable  activity  which  characterizes  that 
hardest-worked  of  human  beings,  a  metropolitan  news- 
paper editor. 

There  are  in  man  certain  morbid  conditions  which 

»  Mbdical  Rbcoxd,  voL  xviiL,  p.  361,  "  Fasdng  Frogs." 


almost  reduce  the  individual  to  the  state  of  a  cold- 
blooded or  hibernating  animal,  as  far  as  the  ability  to 
support  deprivation  of  nutriment  is  concerned.  Not  to 
dwell  on  certain  cases  of  cancerous  stricture  of  the 
pylorus  or  cardia,  where  digestion  and  absorption  are 
almost,  if  not  quite,  impossible,  and  yet  where  we  have 
seen  life  maintained  for  many  long  weeks  on  the  nuiru 
five  reserves  *  of  the  blood  and  tissues ;  there  are  certain 
cases  of  hysteria  characterized  by  chronic  repugnance  to 
and  inability  to  digest  food ;  these  cases  are  called  by 
Huchard  and  Denian  **  gastric  hysteria."  * 

We  here  say  in  advance  that  the  intimate  nature  of  thu 
disease  is  still  unknown  to  science.  Protean  as  are  the 
manifestations,  we  have  not  yet  ascertained  the  nexus  of 
its  part$  or  the  law  of  its  unity.  Believing,  as  we  must 
do,  that  it  has  a  definite  patho-anatomical  basis,  we  are 
forced  to  conclude  that  the  morbid  alterations  are  princi- 
pally molecular,  being  a  disturbance  of  interstitial  pro- 
cesses of  waste  and  repair.  We  are  warranted  in  affirm- 
ing that  in  gastric  hysteria  there  is  marked  inhibition  of 
those  systemic  processes  through  perverted  nervous  in- 
fluence, the  point  of  departure  being  a  local  irritation 
which,  to  the  functions  of  organic  life,  becomes  a  para- 
lyzing lesion. 

In  gastric  hysteria  either  the  appetite  remains  normal 
or  nearly  so,  but  food  is  vomited  shortly  after  it  is  in- 
gested, from  atony  of  the  digestive  organs,  and  failure  of 
the  assimilative  processes ;  or  else  the  appetite  is  com- 
pletely lost,  while  organic  nutrition  is  at  a  stand-still ; 
the  aversion  to  food  is  invincible.  In  the  former  class 
of  cases  abstinence  is  in  some  sort  instinctive,  the  pa- 
tient dreading  the  distress  and  vomiting  which  follow  eat- 
ing. In  the  latter  class  there  is  also  retardation  of  the 
processes  of  vegetative  life,  but  there  is  a  mental  element 
which  is  conspicuous  ;  as  though  the  dread  and  disgust 
of  food  were  a  species  of  insanity,  having  a  special  seat 
in  the  brain.  Huchard  distinguishes  these  two  varieties 
under  the  names  oi  gastric  anorexia  and  mental  anor- 
exia.*  The  mental  anorexia  of  Huchard  has  been  de- 
scribed by  Gull,  of  England,  under  the  name  of  hysterical 
apepsia  ;  **  an  affection  chiefly  seen  in  young  girls  from 
fifteen  to  twenty-three  years  of  age,  and  characterized  by 
complete  loss  of  appetite,  by  emaciation  often  attributed 
to  latent  tuberculosis,  abdominal  disease,  or  tabes  me- 
senterica,  and  due  especially  to  central  cerebral  dis- 
turbance." * 

Other  cases  of  gastric  hysteria  are  distinguished  by 
incoercible  vomiting,  which  may  be  due  to  hyperaesthesia 
of  the  gastric  mucous  membrane,  to  pneumo-gastralgia, 
to  secretory  disturbances  of  the  gastric  glands,  and  to 
other  causes. 

All  the  neuralgic,  spasmodic,  paralytic,  and  other 
nervous  troubles  of  hysteria  in  general,  may  accompany 
this  form  of  hysteria,  and  be  the  key  and  the  exponent 
of  the  malady.  To  cite  one  of  multitudes  of  illustrative 
observations  on  record,  we  may  refer  to  the  very  inter- 
esting case  reported  by  Raymond  in  Vulpian's  "Cli- 
nique  M6dicale,"  obs.  clvi.*     The  patient  was  suflfer- 

>  The  term  is  a  fiiivorite  oae  of  the  late  M.  Benurd. 

*  Huchard:  Trait^  des  n^vroses,  Paris,  1883;  Denian:  De  PHyst^  gM- 
trique,  Paris,  1883. 

*  Huchard  :  Loc.  ciL 

«  Gull :  Brit.  Med.  Jour.,  1873.     (Quoted  by  Denian  in  Hyst^rie  Gastrique.) 

*  Clinique  M^dicale  de  I'Hdpital  de  la  Chants.  Obs.  Oiniques  par  fe  docL  F. 
Raymond.    0«  Doin,  Paris,  1879. 


September  6,  1884*] 


THE  MEDICAL  RECORD. 


269 


jng  from  **  ovarian  hysteria ;  "  entered  the  hospital  to  be 
treated  for  incomplete  paraplegia  which  proved  to  be 
reflex ;  while  in  La  Charity  had  gastric  hysteria,  vomit- 
ing everything ;  this  was  accompanied  by  choreiform 
trembling  of  the  limbs,  which  lasted  for  several  months ; 
both  the  choreic  agitation  and  the  vomiting  were  very 
obstinate ;  there  was  sometimes  alternancy  of  the  mor- 
bid phenomena,  one  kind  being  in  abeyance  while  there 
was  exacerbation  of  another  kind.  The  patient  left  the 
hospital  unrelieved. 

As  for  the  length  of  time  during  which  life  maybe 
maintained  on  such  limited  quantities  of  food  as  are 
assimilated  in  these  cases,  it  is  impossible  to  form  an 
exact  estimate.  Dr.  Car^^enter  relates  an  instance  which 
came  ander  his  own  observation :  '^  A  young  lady  who  had 
just  before  suffered  severely  from  the  tetanic  form  of 
hysteria,  was  unable  to  take  food  (or  three  weeks.  The 
slightest  attempt  to  introduce  a  morsel  of  solid  matter 
into  the  stomach  occasioned  violent  efforts  at  vomiting ; 
and  the  only  nourishment  taken  dturing  the  period  men- 
tioned was  a  cup  of  tea  once  or  twice  a  day,  and  on 
many  days  not  even  this  was  swallowed.  Yet  the  strength 
of  the  patient  rather  increased  than  diminished  during 
diis  period ;  her  muscles  became  firmer  and  her  voice 
more  powerful"  * 

Willen  relates  the  case  of  a  man  who  lived  sixty  days 
without  taking  anything  but  a  little  orange  juice.  Des- 
baireaux  reports  the  history  of  a  woman  who  during 
sixty-one  days  swallowed  only  one  bowl  of  broth.  And 
Desportes  tells  of  a  woman  who  during  two  months  lived 
on  water  alone.  Denian,  from  whom  we  borrow  these 
not  very  well  attested  statements,  after  remarking  the 
downess  of  disassimilation  in  gastric  hysteria^  of  which 
we  have  a  proof  in  the  minute  quantity  of  urea  which  is 
excreted  (in  some  instances  scarcely  thirty  grains  a  day), 
goes  on  to  observe  that  "  alienists  are  every  day  witnesses 
of  facts  of  persisted  anorexia  and  abstinence  supported 
with  an  immunity  truly  astonishing."  * 

The  disposition  to  deceive  which  characterizes  hysteri- 
cal patients  generally  is  not  absent  from  the  gastric  form 
of  the  disease,  and  the  cases  of  Anna  Moore,  Sarah 
Jacobs,  etc.,  reported  by  Dr.  Hammond  in  his  ^  Fasting 
Girls,"  show  us  to  what  bizarre  subterfuges  these  patients 
will  resort  to  impose  upon  family  and  friends,  and  com* 
pel  the  belief  that  absolutely  no  nourishment  of  any  kind 
is  ingested. 

A  notable  instance  of  simulated  fasting,  which  had  a 
tragic  ending,  occurred  in  South  Wales  in  the  spring  of 
1869  {vid^  newspapers  of  that  period,  heading  ''  Fasting 
Girl  oif  South  Wales ").  The  parents  made  a  show  of 
their  child,  decking  her  out  like  a  bride  on  a  bed  and  as- 
serting that  she  had  eaten  no  food  for  two  years.  Some 
reckless  enthusiasts  for  truth  set  four  trustworthy  hospital 
mirses  to  watch  her ;  the  Celtic  obstinacy  of  the  parents 
was  aroused,  and  in  defence  of  their  imposture  (or  be- 
*  cause  they  had  allowed  themselves  to  be  deceived)  per* 
mitted  death  to  take  place  in  eight  days.  Their  trial  and 
conviction  for  manslaughter  are  still  fresh  in  the  memories 
of  inhabitants  of  that  region.* 

Whether  the  same  result  would  follow  a  rigorous  es- 


1  Carpenter :  Prudidct  of  HanuM  Plqrnology,  pi  86.    PhaUu,  i86a. 

SDcniaa  :  Loe.  dc,  p.  55- 

*  Seelbe  acoooat  ia  the  Eacydopedki  Britaoaica,  arlidc  DieteCici. 


pionage,  day  and  night,  of  the  person  and  surroundings 
of  the  fasting  girl  at  Fort  Plain,  is  not  in  our  mind  at  all 
uncertain.  It  would  appear  that  Miss  Kate  Smusley  has 
now  been  for  almost  six  months  "lying  at  death's  door 
from  self-starvation.''  She  occasionally  ''takes  a  little 
water  in  her  mouth,  but  does  not  swallow  it,  as  this 
causes  convulsions  which  wrench  her  stomach  most  pain- 
fully. .  .  .  She  recognizes  her  callers,  and  carries 
on  conversations  with  them,  and  is  perfectly  conscious. 

.  .  .  Her  body  is  in  constant  motion,  like  a  machine, 
so  much  so  that  the  bed  upon  which  she  lies  has  to  be 
supported  for  fear  that  it  will  fall  to  pieces  by  the  con- 
stant vibration.''  Other  non-medical  accounts  of  a  similar 
kind,  based  on  asseverations  of  members  of  the  family, 
are  in  circulation.  We  have  a  medical  opinion  of  the 
case  from  the  statement  of  a  local  physician  whose  name 
we  charitably  suppress,  and  who  considers  the  case  ''one 
of  spinal  disintegration,  or  a  species  of  locomotor  ataxy, 
or  a  wasting  of  the  nervous  system  !  " 

It  is  needless  to  comment  on  such  an  extraordinary 
view  of  a  case  which,  as  far  as  we  have  been  able  to  in- 
form ourselves  concerning  it,  is  clearly  an  instance  of 
gastric  hysteria,  and  presenting  no  single  element  that  is 
essentially  different  from  other  cases  of  the  kind,  unless 
it  be  the  persistent  choreic  trepidation,  which  seems  to 
be  a  more  obstinate  and  formidable  phenomenon  than 
in  Vulpian's  patient  above  referred  to.  There  would 
seem  to  be  a  tetanic  condition  of  the  oesophageal  muscles 
at  times,  making  swallowing  an  impossibility.  We  can 
well  believe  that  Miss  Kate  Smusley  is  a  great  sufferer 
and  entitled  to  universal  pity;  that,  however,  there  is  fraud 
and  imposture  in  the  recital,  as  it  comes  to  us,  there  can 
be  no  doubt  whatever. 


INTRAVESICAL  INJECTIONS. 

Op  the  many  therapeutic  measures  in  common  use  for 
the  alleviation  or  cure  of  vesical  troubles,  few  have  such 
power  for  good,  when  rightly  used,  or  such  injurious 
effects  when  misapplied,  as  injections  into  the  bladder. 
J^en  pense  beaucoup  de  Hen  et  heaucoup  de  mal^  said 
Guion,  when  questioned  as  to  their  value.  Like  most 
of  the  therapeutic  means  in  the  hands  of  the  surgeon, 
whose  value  cannot  be  questioned,  they  are  two-edged 
weapons — excellent,  harmless,  and  productive  of  good 
results  in  experienced  hands,  but  dangerous  when  en- 
trusted to  the  inexperienced  and  ignorant.  Haematuria, 
prostatitis,  cystitis,  and  even  nephritis  are  the  troubles 
arising  from  misuse  of  them,  troubles  depending  upon 
the  technique  of  the  injection,  its  nature,  and  its  pharma- 
ceutical composition. 

Intravesical  injections  may  be  used  in  the  most  diverse 
conditions,  and  to  obtain  essentially  different  results; 
for  a  simple  mechanical  action,  or  for  a  modifying 
dynamic  action  on  the  bladder  or  its  contents,  or  as 
very  necessary  aids  in  certain  operations  upon  the 
bladder. 

Evacuating  injections  or  washes  may  prove  valuable 
mechanical  aids  by  acting  mechanically  on  foreign  sub- 
stances in  the  bladder,  and  causing  their  expulsion. 
The  substances  to  be  removed  may  be  gravels  or  frag- 
ments of  calculi,  or  purulent  or  glairy  masses  which, 
on  account  of  their  weight  or  adhesive  power,  cannot  be 


-270 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


expelled  by  the  forces  of  micturition.  It  is  well  known 
that  in  cases  of  pyluria,  the  last  urine  expelled  contains 
more  pus  than  the  first,  often  consisting  of  almost  pure 
•pus ;  and  the  unexpelled  contents  consist  of  pus,  or  at 
least  urine  mixed  with  pus,  which  stagnates  in  the  blad- 
der, .  Now,  there  is  scarcely  a  surgical  principle  more 
universally  admitted  than  that  every  suppurating  surface 
should  be  placed  under  conditions  favorable  for  cleanli- 
ness and  drainage.  This  is  the  underlying  principle  of 
detersive  vesical  injections,  which  are  indicated  when- 
ever the  urine  contains  pus,  and  especially  when  the 
pus  is  secreted  by  the  vesical  mucous  membrane.  So, 
also,  when  the  urine  undergoes  ammoniacal  fermenta- 
tion, or  there  are  solid  blood-clots  in  the  bladder. 

As  with  other  measures  which  are  powerful  for  good, 
vesical  injections  have  their  contra^indications,  of  which 
pain  may  be  mentioned  first.  The  injection  should  not 
cause  any  considerable  degree  of  pain,  nor  should  the 
bladder  be  distended  by  the  fluid.  After  pain,  acute 
renal  lesions  contra-indicate  detersive  injections.  We 
do  not  say  chronic  lesions  of  the  kidneys,  because  in  that 
case  they  would  be  almost  entirely  thrown  out  of  vesical 
therapeutics. 

It  would  scarcely  be  considered  necessary  to  say  that 
metallic  catheters  should  never  be  used  for  this  purpose, 
unless  we  had  seen  it  done.  Furthermore,  Desnos  has 
shown,  in  his  Lithotritie  d  Stances  Prolongies^  that  an 
evacuating  tube  should  have  two  eyes,  both  for  lithotrity 
operations,  and  for  washing  out  the  bladder.  The  reason 
for  this  is  apparent :  the  contents  of  the  bladder  should 
be  as  much  agitated  as  possible  during  the  injection,  and 
it  is  easily  seen  that  a  tube  with  two  eyes  will  create  a 
double  current,  which  the  smgle  eye  cannot  The 
double-current  canula,  formerly  much  used,  is  decidedly 
disadvantageous  on  account  of  the  necessarily  small  cali- 
bre, its  inability  to  set  up  a  double  current,  and  the  in- 
significant attraction  at  the  external  orifice.  But  of  all 
syringes  for  vesical  injections  the  hydrocele  syringe  is 
probably  the  best.  Whatever  syringe  may  be  used,  how- 
ever, and  however  carefully  it  may  be  graduated,  the 
amount  of  liquid  thrown  in  should  only  be  judged  of  by 
the  resistance  of  the  bladder ;  and  the  injection  cease  at 
or  before  the  first  manifestation  of  vesical  resistance. 

As  it  is  always  unwise  to  empty  a  distended  bladder, 
unless  the  patient  is  in  the  recumbent  posture,  so  vesical 
injections  should  always  be  made  while  he  is  lying  down. 
As  to  the  materials  for  vesical  injections,  it  may  be  said 
in  a  general  way  that  nothing  should  be  used  which  can 
possibly  do  injury,  either  directly  or  indirectly.  For  an- 
tiseptic injections  solutions  of  carbolic  or  boracic  acid, 
resorcine,  corrosive  sublimate,  and  strong  tea,  are  all  ex- 
cellent Nitrate  of  silver  has  been  much  used  in  this 
country,  and  is  still  used  in  France ;  but  the  less  of  that 
material  thrown  into  a  bladder,  so  much  the  better  for  the 
patient 

THE  DEVELOPMENT  OF  CANCER  FROM  CICATRICES  IN 
THE  STOMACH  AND  GALL-BLADDER. 

The  question  whether  cancer  may  have  for  its  starting 
point  simple  ulceration  and  subsequent  cicatrization,  has 
been  fi*equently  raised  in  connection  with  gastric  ulcer. 
While  Rokitansky  and  Dittrich  merely  affirm  that  there 
are  cases  in  which  cancer  has  followed  upon  ulceration. 


Lebert  sees  in  the  not  infrequent  coexistence  of  gastric 
ulcer  and  carcinoma  (9  per  cent  of  his  own  observations) 
more  than  a  chance  occurrence.     And  Leube  ascribes 
to  the  presence  of  an  ulcer  or  its  cicatrix  a  certain  pre- 
disposition for  the  development  of  cancer.     In  a  mono- 
graph on  chronic  ulcer  of  the  stomach,  its  cicatrization, 
and  its  relationship  to  cancer,  reference  to  which  was 
made  in  these  columns  in  September  of  last  year,  Dr. 
Hanser  has  shown  that  the  glandular  changes  induced  by 
the  cicatricial  process  occasion  a  predisposition  to  can- 
cerous growth,  and  that  between  the  cancerous  growth  of 
the  glandular  epithelium  and  its  atypical  growth  in  the 
course  of  cicatrization  there  is  but  a  very  slight  differ 
ence.     Dr.  M.   Heitler,  of  Vienna,  agrees  with  these 
views,  and  in  confirmation  of  their  correctness  cites  three 
cases  with  autopsies,  in  which  cancer  had  arisen  from 
the  cicatrix  following  ulceration.     This  author  further 
states  that  the  same  thing  may  occur  in  the  gall-bladder 
as  in  the  stomach.     In  opposition  to  Frerichs,  Forster 
and  others,  who  regard  the  presence  of  a  cancerous 
tumor  as  favorable  to  the  formation  of  gall-stones,  Klebs 
and  Schiippel  regard  rather  the  irritation  caused  by  the 
presence  of  biliary  calculi  as  favoring  the  development 
of  carcinoma.     Dr.  Heitler  is  led  to  agree  with  the  latter 
by  reason  of  his  own  experience,  jnrhich  though  limited 
to  a  single  case  of  this  kind,  he  holds  to  clearly  establish 
the  correctness  of  the  view  of  Klebs  and  others.    He 
asks  finally  whether,  with  this  experience,  the  appear- 
ance of  cachexia  (especially  when  there  is  unhereditaiy 
history  of  cancer)  should  not  be  regarded  as  an  indica- 
tion for  operative  interference. 


THE    ASSOCIATIONS     FOR     THE     ADVANCEMENT    OP 
SCIENCE. 

The  annual  meeting  of  the  British  Association  for  the 
Advancement  of  Science,  at  Montreal,  last  week,  and  that 
of  the  American  Association,  at  Philadelphia,  this  week, 
have  attracted  unusual  attention.  Both  meetings  have 
been  interesting,  and  have  fairly  served  their  purpose  of 
giving  opportunities  for  social  intercourse  and  mutual 
interchange  of  opinion. 

It  sometimes  occurs  that  subjects  of  much  interest  to 
medical  men  come  up  in  the  Sections  of  Biology  or 
Anthropology.  Such  has  not  been  the  case  this  year, 
and  we  much  regret  the  fact  It  is  noticeable  that  in  both 
France  and  Germany  there  are  scientific  associations 
in  which  the  medical  sciences  form  a  prominent  part 
Such  is  the  case  with  the  French  Association  for  the  Ad- 
vancement of  Science,  and  the  German  Society  of 
Naturalists  and  Physicians.  It  would  be  better  if  cer- 
tain of  the  medical  branches  were  to  ally  themselves  to 
these  associations  for  the  advancement  of  science.  Cer- 
tainly pharmacology,  physiology,  pathology,  and  anatomy 
are  as  legitimate  and  important  sciences  as  any  that  at 
present  receive  attention. 


INDIANA  MEDICAL  AMENITIES. 

An  interesting  controversy  is  going  on  between  the  /»- 
diana  Medical  Journal  and  a  Fort  Wayne  medical  con- 
temporary. The  latter  publication  is  opposed  to  the 
establishment  of  a  Board  of  Medical  Examiners  indepen- 
dent of  the  colleges,  and  to  the  Indiana  Medical  Journal 


September  6,  1884.  J 


THE  MEDICAL  RECORD. 


271 


being  made  the  organ  of  the  State  Society.  It  intimates 
that  those  medical  gentlemen  who  are  not  connected 
with  a  medical  college  are  too  ignorant  to  be  State  ex- 
aminers— ^an  opinion  which  has  been  modestly  advanced 
by  learned  professors  in  our  own  neighborhood.  To  this 
the  Indiana  Medical  Journal  at  once  applies  an  argu- 
mnium  adhominemy  quoting  from  an  article  by  the  learned 
Fort  Wayne  editor,  who,  it  is  needless  to  say,  is  a  full-fledged 
professor  in  a  second-rate  medical  school  It  is  shown 
that  said  professor  advises  the  administration  of  three 
grains  of  quinine  and  three  grains  of  Dover's  powder 
every  three  hours  as  a  "  bitter  tonic "  to  a  child  two 
years  old.  He  also  gives  this  dose  in  the  form  of  a  seven- 
grain  capsule,  the  whole  prescription  being  written  in 
idiat  might  be  called  dog  Latin,  and  displaying  a  massive 
ignorance  of  therapeutic  knowledge  and  literary  skill. 

The  Indiana  Medical  Journal  has  been  making  a  good 
fight  for  reform  in  professional  education  and  ethics  in 
the  State  of  Indiana.  It  is  right  in  its  position  as  to  the 
State  Medical  Examiners,  even  if  its  somewhat  personal 
method  of  argumentation  is  not  conclusive.  Indiana 
needs  a  good  independent  State  Board  of  Medical  Ex- 
aminers much  more  than  it  needs  any  of  the  literary  or 
educational  productions  of  Fort  Wayne. 


CONTAGIOUS   PLEURO-PNEUMONIA. 

Contagious  pleuro-pneumonia  has  already  infected 
several  herds  in  the  West,  although  the  total  number 
of  its  victims  is  still  small,  not  exceeding  fAty.  Much 
to  the  dismay  of  the  milk-dealers,  it  has  been  found  to 
exist  in  an  unequivocal  form  also  in  Brooklyn.  The  dis-* 
ease  has  been  present  at  several  points  in  the  Eastern 
States  for  a  long  time,  and  there  is  no  doubt  that  it  was 
carried  West  from  some  Eastern  herd. 

The  attempts  to  throw  doubt  as  to  the  true  nature  of 
^  disease,  are  simply  the  expressions  of  obstinacy  and 
dubess.  The  disease  is  contagious  pleuro-pneumonia — 
a  thing  not  to  be  trifled  with. 

The  history  of  the  progress  of  pleuro-pneumonia  in  this 
country  of  late  years  has  been  a  curious  illustration  of 
the  advance  of  scientific  knowledge  before  public  opin- 
ion. No  competent  persons  (except  a  few  ''inocula- 
tionists  ")  doubt  that  the  only  way  to  treat  pleuro-pneu* 
nomia  is  to  kill  every  animal  that  has  the  disease,  and 
quarantine  those  that  have  been  exposed.  This  is  the 
cheapest  way  in  the  end,  but  it  has  been  very  hard  to 
show  legislators  that  such  is  the  fac(.  In  the  State  of 
New  York  the  Legislature  has  abandoned  its  special  mar 
diinery  for  dealing  with  cattle  diseases,  and  there  are 
now  only  the  State  and  Local  Health  Boards.  The  con- 
gressional mind  has  never  been  able  to  comprehend  the 
situation,  although  Congress  alone  is  able  to  purge  the 
country  of  the  disease. 

Pleuro-pneumonia  is  a  most  inviting  disease  for  the 
pathologist  to  study.  It  has  a  special  contagion  of  per- 
sistent vitality,  but  generally  of  slow  development.  It 
produces  a  local  disease  wherever  it  fastens  itself,  but 
normally  the  affected  places  are  the  'bronchi  and  air  lo- 
bules. Here  we  have  a  bronchitis,  peribronchitis,  consoli- 
dations, hemorrhagic  infarctions,  and  pleural  efiiision. 

The  general  features  of  the  disease,  however,  were  de- 
scribed in  The  Record  some  time  ago  and  need  not  be 
,  repeated  now. 


^etvs  0£  Vbiz  fiSK^^k 


A  Tribute  to  Marion  Sims. — L  Union  M^icale  of 
August  1 6th  devotes  its  feuilleton  to  au  account  of  the 
life,  work,  and  character  of  the  late  Dr.  Marion  Sims. 

Symmetrical  at  Least. — In  Italy  cholera  attacks 
the  peasants,  the  peasants  attack  the  doctors,  and  the 
doctors  attack  the  cholera.  The  cholera  seems  to  be 
coming  out  ahead,  perhaps  the  peasants  come  next. 

Dr.  Oliver  Wendell  Holmes  celebrated  his  seventy- 
fifth  birthday  on  August  29th.  He  received  the  con- 
gratulations personally,  by  mail,  and  by  telegraph  of  a 
large  circle  of  friends  and  admirers  throughout  this  coun- 
try and  Europe. 

Appointments  in  the  Faculty  of  Medicine  of 
Paris. — M.  Lannelongue  has  been  made  Professor  of 
External  Pathology  in  the  Faculty  of  Medicine  of  Paris. 
M.  Armand  Gautier  has  been  made  Professor  of  Medical 
Chemistry  in  the  same  faculty. 

A  New  Medical  Author. — ^A  contemporary  says: 
"  Jahrbuch  reports  the  treatment  of  forty-three  cases  of 
diphtheria  with  oil  of  turpentine."  Dr.  "  Jahrbuch  "  had 
excellent  results.  We  are  reminded  of  the  Freshman 
who  inquired  at  the  library  for  the  works  of  "  Ibid." 

The  Treatment  of  Dysentery  by  Corrosive  Sub- 
limate AND  CoLOCYNTH. — Dr.  F.  Sieber,  of  Chicago, 
IlL,  writes  us,  calling  attention  to  the  fact  that  the  method 
of  treating  dysentery  advocated  by  Dr.  S.  W.  Childs  in 
The  Record  of  August  23d  is  no  new  thing,  but  was  de- 
scribed in  The  Medical  Record,  vol.  xiv.,  pp.  45  and 
194. 

The  Cholera  continues  to  spread  in  the  Pyrenees 
villages  and  has  finally  reached  Madrid,  Spain,  where  it 
has  caused  great  consternation*  It  has  also  extended  itself 
still  further  through  Italy,  having  infected  eleven  provinces 
already.  The  total  number  of  deaths  from  cholera  up  to 
September  4th  is  over  5,000.  The  cholera  is  now  killing 
about  one  hundred  persons  a  day,  if  the  telegraphed  re- 
ports are  correct. 

The  Death  of  Dr.  J.  Collis  Browne  is  announced 
from  London.  He  formerly  belonged  to  the  medical 
staff  of  the  British  Army,  and  devised  the  well-known 
preparation  ''  chlorodyne,"  for  the  cure  of  diarrhoea  and 
similar  diseases  prevalent  in  the  tropical  possessions  of 
England.  Although  the  remedy  was  largely  imitated  and 
counterfeited,  it  is  said  to  have  secured  great  wealth  for 
its  inventor. 

A  Mild  Form  of  Hydrophobia.— There  seems  to  be 
little  doubt  that  the  following  curious  series  of  events  oc- 
curred near  Eufaula,  Ala.  On  July  25  th  a  dog  on  a 
plantation  bit  a  mule  and  several  hogs ;  nineteen  days 
later  the  mule  and  one  of  the  hogs  died  with  the  symp- 
toms of  tetanus.  Within  the  next  week  three  more  of 
the  bitten  hogs  died  with  the  same  symptoms.  The 
dead  hogs  were  eaten  by  some  thirty  negroes,  about  half 
of  whom  were  within  ten  or  fifteen  days  attacked  with 
what  Dr.  Johnson,  the  attending  physician,  calls  ^'  a  mild 
form  of  hydrophobia." 

Death  of  Dr.  Robert  J.  Heinmuller. — ^We  regret 
to  announce  the  death  of  Dr.  Robert  J.  Heinmuller,  on 


272 


THE  MEDICAL  RECORR 


[September  6,  1884. 


August  30th,  at  his  home  in  this  city,  of  apoplexy.  He 
was  twenty-nine  years  of  age,  and  a  graduate  of  the  Uni- 
versity Medical  College.  Since  1881  he  had  been  con- 
nected with  the  Health  Department,  and  held  the  position 
of  Assistant  Sanitary  Inspector  in  the  Bureau  of  Conta- 
gious Diseases.  He  was  a  member  of  the  County  Medi- 
cal Society,  and  of  the  Physicians'  Mutual  Aid  Associa- 
tion. He  had  been  an  interne  at  Bellevue  Hospital,  and 
was  for  a  time  well  known  as  a  quiz  master. 

Some  Dubious  Advice  Regarding  the  Cholera. — 
A  French  doctor  being  applied  to  by  his  mother-in-law 
for  a  receipt  to  keep  off  the  cholera,  recommended  the 
following  prophylactic  regimen  :  Sit  for  a  quarter  of  an 
hour  morning  and  evening  in  a  strong  draught.  Drink  at 
each  meal  a  bottle  of  adulterated  wine.  Eat  two  green 
melons  at  breakfast,  the  same  number  at  dinner.  Walk 
in  the  sun  with  the  head  uncovered  for  an  hour  every 
noon.  Get  yourself  into  a  violent  perspiration,  then 
drink  a  pitcher  of  ice-water  and  sit  in  the  cellar  in  a 
chemise.  Drink  ice-water  every  hour  that  it  is  hot.  Le 
culte  de  Venus  matin  et  soir.  If  you  have  any  early 
symptoms  of  cholera,  don't  believe  it. 

The  Danger  from  Chinese  Lepers. — Says  The  Pa- 
cific Medical  and  Surgical  Journal :  "  Since  the  founda- 
tion of  the  State  of  California,  thirty-five  years  ago,  Chinese 
immigration  has  gone  on,  with  the  introduction  of  occa- 
sional cases  of  leprosy,  and  in  all  those  years,  comprising 
more  than  a  third  of  a  century,  only  one  doubtful  case  of 
leprosy  has  been  found  to  prove  the  risk  of  the  disease 
extending  to  the  white  population.  The  subject  has 
more  than  once  been  considered  by  the  State  Board  of 
Health,  and  not  a  solitary  instance  has  been  reported 
from  any  part  of  the  State."  It  is  interesting  to  compare 
this  statement  with  the  history  of  leprosy  in  the  Sandwich 
Islands,  where  the  disease  has  spread  so  disastrously. 

Home  Criticisms  op  the  American  Institute  op 
Homceopathv. — The  New  York  Medical  Times  (homoeo* 
pathic,  in  a  measure)  charges  the  American  Institute  of 
Homoeopathy  with  being  a  machine-ridden  and  obsolete 
institution  which  has  outlived  its  usefulness.  It  calls 
upon  it  to  renounce  its  title  or  disband,  and  states  what 
is  now  very  well  known,  that  *'  homoeopathic  colleges," 
'^  homoeopathic  publishers,"  ''  homoeopathic  pharmacies," 
etc.,  cling  to  their  distinctive  name  because  it  is  a  trade- 
mark without  which  they  would  become  extinct  When 
the  leading  homoeopathic  (we  beg  its  pardon)  journal  of 
the  country  talks  in  this  bold  way,  we  opine  that  the 
end  is  near.  Homoeopathy  should  be  taught  in  all  medi- 
cal colleges  as  a  branch  of  historical  medicine,  or  psycho- 
logical therapeutics.  In  that  direction  matters  are  rapidly 
tending. 

A  Case  op  Yellow  Fever  was  discovered  in  this  city 
last  week.  The  patient  was  picked  up  in  an  unconscious 
condition  on  the  street,  and  no  history  of  his  illness  could 
be  obtained.  From  his  appearance  it  seemed  probable 
that  he  was  a  sailor.  He  was  taken  to  the  New  York  Ho^ 
pital,  where  he  continued  semi-comatose,  but  developed 
a  high  temperature.  Symptoms  of  black  vomit,  yellow  skin, 
and  subcutaneous  hemorrhage  appeared.  He  died  the 
next  morning.  Post-mortem  examination  revealed  a  yellow, 
mottled  liver,  hemorrhage  in  the  stomach  and  intestines 


as  well  as  in  the  lungs,  enlarged  spleen,  and  yellow  kid- 
neys. The  black  vomit,  the  pronounced  yellow  staining 
of  the  skin,  and  the  subsequent  discovery  of  gastro-intes- 
tinal  and  pulmonary  hemorrhages  justify  the  diagnosis 
which  was  made.  For  further  particulars  we  refer  to  the 
report  of  Dr.  Francis  E.  Dwight,  House-Physician  to  the 
New  York  Hospital,  on  page  264.  Since  the  occurrence 
of  this  case  reports  of  two  others  in  Brooklyn  have  ap- 
peared  in  the  daily  papers,  but  these  lack  confirmation. 

The  First  Manupacturer  op  Pepsin. — At  the 
meeting  of  the  American  Pharmacological  Association  at 
Milwaukee,  last  week,  Mr.  Henry  Biroth,  of  Chicago,  ex- 
hibited several  bottles  of  a  preparation  called  "  pepsan," 
which  he  believed  to  be  of  historical  interest  The  prep* 
aration,  he  said,  was  put  up  in  1853  ^X  ^^^  'Sbexi  Owen, 
of  Chautauqua  County,  N.  Y.  Owen  lived  the  life  of  a 
hermit,  and  was  generally  spoken  of  as  "  Crazy  Owen." 
When  he  died  his  cabin  was  found  to  contain  several 
packing  cases  filled  with  bottles  of  the  preparation  which 
he  called  ''pepsan,"  and  which  he  had  pat  up  himself. 
Accompanying  the  stuff  were  printed  circulars  quaintly 
worded  as  follows : 

Pepsan,  for  the  cure  of  dyspepsia,  jaundice,  liver  com- 
plaint, together  with  all  diseases  arising  from  a  disorgani- 
zation of  die  stomach.  This,  I  believe,  is  the  gastric 
juices  of  the  stomach  of  the  ox  producing  the  gastric  juice 
required  by  man  to  digest  his  food.  Prepared  by  Eben 
Owen ;  by  no  other,  I  believe,  in  this  world.  Directions 
for  using :  Take  a  small  half-teaspoonful  fifteen  minutes 
before  eating  in  a  half  gill  of  cold  water.  My  advice  is  to 
eat  light  suppers.  This  is  got  up  under  prayer,  and  will 
do  good  I  believe.  Ebbn  Owen. 

.XApril>5.1 

Mr.  Biroth  stated  that  the  so-called  ''pepsan"  was 
vfbaX  is  now  known  as  ''  pepsin,"  and  intimated  that  the 
valuable  aid  to  digestion  now  known  and  used  by  dys- 
peptics the  world  over  was  originally  discovered  and 
manufactured  by  "  Crazy  Owen." 


Veratria  in  the  Treatment  op  Muscular  Tre- 
mors.— Dr.  Feris  has  employed  veratria  in  a  number  of 
cases  of  tremor  from  alcoholism,  in  convalescence  from 
t3rphoid  fever,  and  in  multiple  sclerosis.  In  every  case 
the  tremor  was  quickly  overcome,  but  in  the  last  instance 
the  improvement  was  only  temporary.  From  his  ex- 
perience in  these  cases  the  author  formulates  the  foUow- 
mg  conclusions :  i.  Veratria  cures  muscular  tremor 
occurring  in  alcoholism  and  in  certain  nervous  affections. 
It  wiU  probably  cure  all  forms  of  tremor,  but  is  especially 
serviceable  in  that  of  alcoholism.  2.  The  effects  of  the 
remedy  begin  to  be  manifested  within  twenty-four  hours. 
3.  In  cases  in  which  veratria  is  of  avail  it  overcomes  all 
tremor,  not  only  of  the  hands  but  also  of  the  tongue,  h'ps, 
etc  4.  The  influence  of  the  treatment  is  prolonged 
The  author  has  seen  the  relief  persist  for  two  mcraths; 
The  dose  is  four  pills  per  diem,  each  pill  containing 
^  milligr.  (about  ^^  g^^^  of  veratria). — Eiznsta  CUnica 
e  Terapeuiicay  No.  6,  1884. 

iQPoTASH  Chlorate  in  Gonorrhcea. — Dr.  J.  Milton 
{Medical  Age,  April  25,  1884)  states  that  he  has  had 
excellent  results  from  the  internal  use  of  the  following 
mixture  in  ordinary  cases  of  gonorrhoea :  Potash  chlorate 
two  drachms,  boiling  water  four  ounces.  Mix  and  shake 
till  solution  is  accomplished;  then  add  potass,  acetat 
two  drachms,  spirits  of  juniper  four  drachms,  camphor 
mixture  six  ounces.  M.  S.  Dose,  a  tablespoonful  twice 
daily. 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


273 


3epovts  at  S^ocUtuB. 


THE  INTERNATIONAL  MEDICAL  CONGRESS. 

£i^MA  Session^  held  in  Copenhagen^  Denmark,  August 
10  to  16,  1884. 

General  Summary  of  Proceedings. 

(From  our  Special  Correspoodent. ) 

COPBNHAGBN,  DSNMAKK,  AugUSt  Z8,  Z884. 

On  Saturday,  August  i6th,  the  president  of  the  Eighth 
Session  of  the  International  Congress  bade  adieu  to  the 
members,  and  in  a  few  simple  and  evidently  heartfelt 
words,  closed  the  series  of  most  successful  meetings 
which  have  just  been  held  at  Copenhagen. 

The  old  French  custom,  which  is  expressed  by  the 
words,  "Le  Roi  est  mort,  vive  le  Roi,"  was  here  im- 
proved upon.  The  reigning  Congress  was  not  yet  dead 
before  its  successor  was  decided  upon  and  proclaimed. 
After  Professor  Panum  had  delivered  the  closing  general 
address  (see  page  203), 

ON  THE   INVESTIGATIONS   OF   FOOD  RATIONS   FOR  MEN   IN 
A    STATE   OF   HEALTH   AND    DISEASE, 

the  report  of  the  committee  upon  the  invitation 

TO  HOLD  THE   NEXT  CONGRESS   AT  WASHINGTON,    IN   SEP- 
TEMBER, 1887, 

was  read,  and,  as  akeady  cabled,  adopted. 

There  were  a  great  number  of  excellent  papers  read, 
and  important  discussions  held  in  the  diflferent  sections, 
the  results  of  which  will  soon  be  laid  before  the  medical 
world. 

A  VERY   LARGE  ATTENDANCE. 

In  a  previous  letter  reference  was  made  to  the  open- 
ly proceedings ;  but  it  was  not  till  the  meeting  was  well 
advanced  that  a  reliable  estimate  could  be  formed  as  to 
the  character  and  dimensions  that  the  gathering  would 
mtunately  assume.  No  one,  and  least  of  all,  apparently, 
mose  who  were  organizing  the  matters  here  m  Copen- 
hagen,  had  the  lea.st  idea  that  the  Congress  would  attract 
the  numbers  it  had  done. 

,  By  Wednesday  morning,  when  the  sittings  of  the  sec- 
tions were  suspended  for 

THE   EXCURSION  TO   ELSINORE, 

the  membership  had  grown  to  between  sixteen  and  sev- 
Mteen  hundred,  and  the  number  of  foreign  members 
who  had  been  attracted  to  the  great  Congress  of  1881 
had  been  greatly  exceeded  This  unexpected  develop- 
ment,  so  far  as  regarded  the  membership  of  the  Congress, 
would  be  sufficient  to  account  for  any  hitch  which  might 
ocoir  m  the  organizing  machinery.  Nobody,  accord- 
ingly, was  disposed  to  be  over-querulous  by  reason  of 
the  fact  that 

THE    LODGING    CAPACITY   OF  THE    DANISH   CAPITAL 

TO  felt  to  be  uncomfortably  straitened.  The  least  sat- 
isactory  result  was  seen  m  the  sectional  arrangements, 
which  will  probably  make  the  preparation  of  the  Con- 
gress transactions  very  difficult,  if  not  impossible,  of 
complete  attainment.  From  the  same  causes  which 
were  at  work  in  this  last  respect,  representatives  of  the 
several  medical  journals  found  it  more  than  usually  diffi- 
cult to  gather  up  anything  like  a  complete  r^sum^  of  the 
sectional  proceedings. 

SECTIONAL   WORK. 

For  the  English-speaking  members,  however,  interest 
centred  most  largely  in  the  sections  of  surgery  and  medi- 
cine; and  in  the  case  of  these  two  I  shall  be  enabled  to 


present  in  The  Medical  Record  sufficiently  full  and 
reliable  abstracts  of  the  papers  and  debates. 

hospitalities. 

As  to  the  hospitalities  and  courtesies,  these  at  no  time 
showed  signs  of  break-down.  The  private  hospitalities 
of  the  Danish  physicians  will  live  long  in  the  recollection 
of  their  special  recipients.  But  of  the  unfailing  courtesy, 
kindliness,  and  even  exuberant  hospitality  shown  to  every 
member  of  the  Congress  by  the  king,  profession,  and 
people  alike,  the  memory  will  only  die  with  the  life  of 
each  and  every  member.  The  king  showed  from  the  be- 
ginning to  the  end  of  the  meeting  his  warm  appreciation 
of  the  intellectual  distinction  which  its  presence  conferred 
on  his  capital  His  presence  added  lustre  to  the  opening 
meeting  of  the  Congress,  his  kindly  and  generous  good- 
will gave  the  members  the  pleasure,  on  the  Wednesday,  of 

A  VISIT  TO   ELSINORE, 

which  will  not  l>e  readily  forgotten,  and,  on  the  Friday 
evening  extended  to  them  the  honor  and  enjoyment  of 
a  reception  and  supper  at  the  palace  of  Christiansborg, 
at  which  the  king  and  queen,  and  all  the  members  of  the 
royal  family  were  present.  The  dinner  given  by  the 
municipality  on  Thursday  evening  may  be  described,  for 
want  of  a  better  adjective,  as  also  right  royal  in  charac- 
ter ;  and  the  popular  appreciation  of  the  work  of  the 
Congress  and  its  representative  men,  was  completed  by 
the  fete  given  to  the  members  in  the  Tivoli  Gardens  on 
the  same  evening,  and  by  the  farewell  feast  given  on  the 
night  of  Saturday  in  the  national  establishment. 

[The  scope  of  the  general  addresses  has  been  indicated 
by  summaries  which  have  been  sent  by  cable.  In  two 
of  them — those,  namely,  of  Sir  William  Gull  and  of  Pro- 
fessor Panum — as  already  stated,  proposals  were  made 
for  collective  investigation.  Professor  Panum's  proposi- 
tion did  not  result  in  any  definite  action  on  the  part  of 
the  Congress.     But  in  the  case  of 

THE   COLLECTIVE   INVESTIGATION   OF  DISEASE 

a  different  course  was  taken  and  the  following  committee 
was  appointed ;  Professors  Trier  and  Lange,  of  Copen- 
hagen ;  Drs.  Bull,  of  Christiania;  Rauchfuss,  of  St.  Peters- 
burg ;  Schnitzler,  of  Vienna ;  Pribram,  of  Prague  ;  Bou- 
chard, of  Paris ;  Lepine,  of  Lyons ;  Ewald  and  Bern- 
hardt, of  Berlin  ;  Sir  William  Gull,  Professor  Humphrey, 
and  Dr.  Mahomed,  of  England ;  Sir  Joseph  Fayrer,  Lon- 
don ^India) ;  Professor  Jacobi,  of  New  York  ;  Dr.  Davies, 
of  Philadelphia ;  Dr.  Goutteriez  Ponce,  of  Colombia ; 
Professor  Despine,  of  Geneva ;  and  Dr.  Isambard  Owen, 
of  London,  Secretary  General.] 


As  to  the  work  of  the  sections,  it  has  already  been  in- 
dicated that  the  section  on  surgery  was  the  one  in  which 
centred  the  chief  interest  of  the  meeting.  Here,  perhaps, 
the  most  important  discussion  was  that  which  took  place  on 

THE  LISTERLAN  SYSTEM  OF  ANTISEPTICS, 

and  which,  while  it  showed  the  continued  existence  of  a 
sincere  and  general  acceptance  of  the  principles  under- 
lying antiseptic  surgery  and  admiration  for  its  author,  at 
the  same  time  exhibited  an  immense  variety  of  opinion 
and  practice  as  to  the  methods  after  which  surgeons  seek 
to  follow  out  their  principles. 

Interesting  and  important  discussions  were  held  on  the 
paper  of  Mr.  MacEwen,  of  Glasgow,  on 

OPERATION   FOR   GENU   VALGUM, 

this  particular  debate  being  remarkable  for  the  almost 
complete  renunciation  of  their  own  methods  by  other  sur- 
geons in  favor  of  Mr.  MacEwen' s ;  on  the  paper  of  Whit- 
spn,  of  Glasgow,  on  the  treatment  of  club-foot;  on  a 
paper  of  Professor  Oilier,  of  Lyons,  on  the  operation  of 
arthrotomy  for  tuberculous  joint  affections ;  and  on  the 
subject  of  extirpation  and  other  operations  for  the  cure 
or  relief  of  malignant  disease  of  the  rectum,  introduced 


274 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


in  a  remarkable  communication  by  Professor  Esmarch, 
of  Kiel. 

In  the  medical  section  there  was  a  comparative  ab- 
sence of  large  debates  on  subjects  of  a  very  general 
interest,  except  perhaps  in  the  instance  of  the  ques- 
tions of 

TUBERCULAR  PATHOLOGY  AND  TREATMENT, 

and  on  the 

MALARIAL   INFECTION    IN    MAN. 

The  first-mentioned  discussion  was  noteworthy  chiefly 
on  account  of  the  declaration  of  Professor  Jaccoud,  of 
Paris,  as  to  the 

ALMOST  UTTER  STERILITY,  FROM  A  CLINICAL  POINT  OF 
VIEW,  OF  DR.  KOCH'S  DISCOVERY  OF  THE  BACILLUS 
TUBERCULOSIS. 

Further  observations  might,  he  said,  be  followed  by  more 
encouraging  results;  but  so  far  at  least  the  discovery 
had  borne  no  fruit  in  the  treatment  of  the  disease. 

In  the  same  section  some  progress  was  made  in  the 
report  of  Dr.  Austin  Flint's  committee,  in  regard  to  the 
question  of  the  establishment  of  a 

UNIFORM    NOMENCLATURE   OF  AUSCULTATORY  SOUNDS   IN 
THE   DIAGNOSIS   OF  DISEASES   OF  THE   CHEST. 

The  like  question  of  international  uniformity  of  nomen- 
clature came  up  in  the  section  of  gynecology  and  obstet- 
rics on  the  report  of  Professor  Simpson's  committee ;  and 
in  this  case  the  section  reaffirmed  the  importance  and  de- 
sirability of  the  object  in  view,  and  reappointed  the 
committee  for  further  consideration  of  the  question  and 
report  to  the  next  Congress. 

Of  the  other  work  in  this  section  that  which  excited 
most  interest  was  a  prolonged  debate  on  the  question  of 


TREATMENT  OF    UTERINE    FIBROMATA    BY    LAPAROTOMY, 


introduced  by  a  paper  by  Dr.  Koeberle,  of  Strassburg,  and 
on  kindred  subjects  of  abdominal  surgery — the  debate 
being  taken  part  in  by,  among  others.  Professor  Eustache, 
and  Dr.  Apostoli,  of  Paris ;  Dr.  Margary,  of  Turin ;  and 
Sir  Spencer  Wells,  of  London. 

Of  the  other  sections  that  of  skin  diseases  perhaps 
came  next  in  interest.  Here  again  the  question  that 
most  excited  debate  was  that  as  to  the 

TUBERCULOUS  CHARACTER  OF  THE  LUPUS. 

Professor  Kaposi,  of  Vienna  found  himself  practically 
alone  and  unsupported  in  the  negative  view  of  this  ques- 
tion, as  against  Professor  Doutrelepont,  of  Bonn ;  Dr. 
Lelair,  of  Paris  ;  Professor  Nierser,  of  Breslau ;  and  Pro- 
fessor  Lang,  of  Insbruck.  Of  special  interest  was  a  com- 
munication by  Dr.  Goldscheider  on  the 

SPECIFIC   SENSIBILITY  OF  THE   SKIN. 

Prolonged  consideration  and  discussion  of  different 
phases  of  syphilis  was  given  rise  to  by  a  paper  by  Pro- 
fessor Pick  on 

EXCISION  OF  THE   INITIAL   SCLEROSIS   IN   SYPHILIS,"] 

and  other  communications. 

Questions  as  .to  tubercular  conditions  cropped  up  in 
others  of  the  sections,  as  in  that  of  pathology  and  morbid 
anatomy,  the  impulse  to  the  discussion  being  given  by 
a  paper  of  Professor  Chauveau,  of  Lyons,  on  the 

IMPORTANCE  TO  BE  ATTACHED  TO  TUBERCULOSIS  IN  DO- 
MESTIC ANIMALS,  CONSIDERED  AS  A  SOURCE  OF  TUBER- 
CULOSIS IN  MAN, 

and  a  relative  paper  by  Professor  Bang,  of  Copenha^ 
gen. 


In  the  same  section  Sir  William  Gull  and  Professor 
Comil,  of  Paris,  read  papers  on 

NEPHRITIS   AND   ITS   SPECIAL  TISSUE-CHANGES. 

In  the  section  of  ophthalmology  of  special  importance 
was  a  paper  of  Professor  Holmgren,  of  Upsala, 

ON  THE    COLOR   SENSE  ;     | 

as  to  which  several  new  and  interesting  points  were 
brought  forward.  Another  matter  of  interest  in  this  sec- 
tion was 

THE  INFLUENCE    OF    JEQUIRFTY    IN   GRANULAR    CONJUNC- 
TIVITIS AND  PANNUS; 

and  of  interest  were  papers  on  "  Latent  Squint,"  by  Drs. 
Hansen-Grut,  of  Copenhagen,  and  Noycs,  of  New  York. 

THE   SUBJECT  OF   REf^RACTION 

was  introduced  in  a  paper  by  Professor  Schmidt-Rimpler, 
of  Marburg,  who  detailed  a  new  method  of  estimating  re- 
fraction by  means  of  the  ophthalmoscope.  The  subject 
was  well  discussed  from  a  practical  point  of  view  by 
Noyes,  Berry,  Juler,  Sattler,  and  others. 

THE   FEATURES    OF    THE   WORK   IN  THE   SECTION  OF  LA- 
RYNGOLOGY 

which  were  of  practical  interest  were  found  in  papers  of 
Dr.  F.  Lemon,  of  London,  on  an  "  Etiological  Classifica- 
tion of  Motor  Impairments  of  the  Lar3mx,"  with  a  rela- 
turc  by  Dr.  Cadier,  of  Paris,  on  **  Paralysis  and  Parescs 
of  the  Larynx.'* 

Dr.  Lcfferts,  of  New  York,  read  a  very  interesting  paper 
on  the  "  Operative  Removal  of  Foreign  Bodies  from  the 
Air- passages." 

Dr.  Cohen  read  a  paper  on  "  Prognostic  Significance 
of  the  Several  Local  Manifestations  Observed  in  Tubercu- 
losis of  the  Larynx." 

In  military  medicine,  Dr.  Schmulewitsch's  paper  was 
one  of  interest ;  but  some  subjects  put  down  in  this  sec- 
tion were  discussed  in  the  surgery  section  by  the  two  sec- 
tions jointly,  viz.,  those  on  antiseptics. 

OPERATIVE    TREATMENT   OF    MALIGNANT    RECTAL    AFFEC- 
TIONS. 

Professor  Esmarch,  in  his  paper  on  this  subject  be- 
fore the  surgical  section,  laid  down  the  same  principles  of 
treatment  for  cancer  of  the  rectum  as  for  cancer  else- 
where. Removal  of  the  disease  must  be  early  and  entire. 
Cases  were  usually  recognized  too  late,  being  earlier 
treated  as  piles,  and  a  rectal  examination  too  long  de- 
ferred. The  affection  was  painless  in  the  early  subject 
Experience  showed  that  after  early  and  total  removal  a 
permanent  cure  resulted.  The  lymphatic  glands  were 
affected  late  and  rarely.  Czemy  had  cases  of  permanent 
recovery,  although  the  disease  had  existed  for  three  years. 
The  prognosis  was,  therefore,  good.  First,  as  to  principle, 
the  amputation  of  the  rectum  above  the  limits  of  the  dis- 
ease was  in  every  case  indicated.  The  dangers  were 
hemorrhage — which  was  to  be  controlled  by  care,  double 
ligature  of  all  vascular  parts  divided^ — and  infection,  which 
was  to  be  guarded  against  by  irrigation  and  drainage. 
To  permit  the  faeces  to  pass,  a  large  rubber  drain  was 
needed,  surrounded  by  sublimated  gauze.  The  perito- 
neum must  inevitably  be  opened  where  amputation  was 
high.  Modem  methods  had  reduced  the  mortality  to 
twenty  per  cent.,  and  the  troubles  resulting  from  the 
operation  were  insignificant.  Suture  of  the  two  ends  to* 
gether  was  bad,  causing  gangrene  and  stricture.  The 
anus  and  sphincter  were  to  be  leffc,  and  the  coccyx  need 
not  be  excbed  for  space. 

Professor  Verneuil  said  he  had  done  his  first  colot- 
omy  Uiirty  years  ago,  and  his  first  extirpation  fifteen  years 
ago.  He  at  once  found  the  removal  of  the  disease  was  im- 
possible, the  patients  objected  or  refused  in  many  cases  to 
allow  the  performance  of  colotomy.     He  then  found  the 


September  6,  1884. J 


THE  MEDICAL  RECORD. 


275 


incision  of  the  cavernous  stricture  removed  all  complica- 
tioQS  and  gave  all  the  other  advantages  of  colotomy.  The 
whole  length  of  the  stricture  must  be  split.  The  incision 
was  made  from  the  tip  of  the  coccyx  by  a  thermal  cau- 
tery plunged  in  to  meet  the  tip  of  the  finger  hooked  above 
the  stricture.  Through  this  channel,  by  a  canula,  if  nec- 
essaiy,  an  toraseur  diain  was  passed,  and  the  rest  of 
the  division  completed.  No  blood  was  ever  lost,  and 
symptoms  at  once  ceased.     No  deaths  followed. 

Professor  Tr^lat  denied  the  advantage  claimed  for 
the  rectal  extirpation,  and  pointed  out  the  rapidity  and  ma- 
lignity of  the  recurrence.  He  quoted  one  case,  which  he 
said  was  the  type  of  many,  where  the  removal  of  the  can- 
cer early,  and  when  extremely  small,  was  followed  by  a 
speedy  and  malignant  recurrence.  In  one  case  he  found, 
though  the  operation  was  normal  and  extra-peritoneal, 
that  he  had  the  small  intestine  in  the  artificial  anus,  and 
the  patient  died.  He  laid  stress  upon  the  color  of  the 
mtestine,  as  the  only- part  of  recognition  that  did  not  de- 
ceive, being  white  or  grayish  white. 

Mr.  Sampson  Gamgee,  of  Manchester,  preferred  the 
operation  of  inguinal  colotomy,  while  admitting  that  the 
other  operations  had  their  indications,  but  that  no  one 
could  dominate. 

Mr.  Marshall,  of  London,  in  support  of  the  state- 
ments of  Professor  Verneuil,  mentioned  some  cases  where 
sinuses  had  been  kept  open  in  the  peritoneum  by  tangle 
tents. 

Professor  Volkmann,  of  Halle,  observed  that  colot- 
omy, erven  in  Mr.  Bryant's  hands,  was  a  very  dangerous 
operation,  and  that  the  statistics  of  extirpation  were 
better  than  those  of  the  colotomy  of  Bryant.  Cancers,  he 
said,  varied  in  rapidity  and  malignity,  according  to  their 
locality,  and  in  the  rectum  they  had  little  tendency  to  in- 
filtrate early  and  recur  soon.  Even  in  desperate  cases 
he  had  no  return  under  long  periods,  in  one  case  not  for 
ten  years.  In  chronic  irritation  a  barrier  surrounded 
the  infiltrated  carcinoma  recti.  The  results  of  rectot- 
omy  bad  improved,  and  would  go  on  doing  so  with  im- 
proved technique.  Asepsis  and  disinfection  were  normally 
powerfiil  when  the  peritoneum  was  not  opened  ;  but  when 
this  was  opened  the  dangers  were  great,  and  cleansing 
difficult  But  dangerous  as  extirpation  was,  it  was  not 
so  bad  as  colotomy,  and  recurrences  were  painless  and 
not  troublesome.  The  comfort  of  patients  was  also  in- 
finitely greater  than  it  was  after  colotomy,  discomfort  be- 
ing hardly  felt  save  in  diarrhoea.  The  selection  of  the 
cases,  he  went  on  to  say,  was  also  important,  and  he  did 
not  operate  in  any  case  where  he  could  not  reach  the 
upper  end  of  the  disease  by  bimanual  exploration  under 
anaesthesia.  The  incision  should  be  both  forward  and 
back  to  the  coccyx,  the  anus  alone  being  left,  and  no  at- 
tempt should  be  made  to  unite  the  upper  with  the  lower 
end,  which  should  be  stitched  well  down,  and  the  cavities 
at  the  sides  well  drained.  Extirpation  he  characterized 
as  a  blessed  operation. 

Mr.  Henry  Morris,  of  London,  went  over  the  Eng- 
lish reasons  for  preferring  colotomy  in  the  lumbar  region. 

Professor  Kuster  said  that  in  extirpation  he  al- 
ways stitched  down  when  the  peritoneum  had  been 
opened.  He  used  iodoform  in  some  cases,  with  tempo- 
rary benefit.  Cauterization  was  a  proceeding  from  which 
good  results  were  obtained  in  most  of  the  cases  where  a 
permanent  cure  could  not  be  expected.  He  would  se- 
lect either  that  or  extirpation — ^very  seldom  colotomy. 

Professor  Pacquet,  of  Lille,  read  a  paper  on 

UNUATERAL  HYPEROSTOSIS   OF  ALL  THE   BONES   OF  THE 
HEAD, 

excision  of  the  upper  jaw,  and  arrest  of  the  hjrperostosis 
in  all  the  other  bones  ;  and  he  showed  a  preparation  de- 
monstrating the  excision. 

Professor  Trelat,  at  the  conclusion  of  the  demon- 
stration, observed  that  whatever  might  be  said  for  the 
theory  of  the  operation,  the  specimen  shown  to  the  sec- 
tion was  one  simply  of  osteo-myelitis. 


Professor  Pacquet  thereupon  made  some  amusement, 
withdrew  the  specimen  as  having  been  submitted  by  mis- 
take, and  showed  another,  which  he  declared  to  be  the 
proi^r  one. 

Dr.  a.  Van  Derveer,  of  Albany,  read  a  paper  on  the 

treatment   of  the   intermaxillary  bone  in  cases 
OF  cleft  palate 

with  double  harelip. 

Dr.  Reginald  Harrison,  of  Liverpool,  read  a  paper 
on  the 

treatment  of  certain  cases  of  prostatic  obstruc- 
tion  BY  section  of  the   GLAND. 

Professor  Volkmann  said  that  drainage  through  the 
perineum,  without  incision  of  the  prostate,  was  sufficient, 
and  that  the  prostate  afterward  shrunk. 

EXCISION  AND  ARTHROTOMY  IN  TUBERCULOUS  JOINT   DIS- 
EASES. 

Professor  Ollier,  of  Lyons,  read  a  paper  on  the 
above  subject,  containing  a  general  examination  of  the 
extent  and  results  of  resection  and  similar  operations  ia 
tumor  albus.  Dealing  with  arthrotomy,  he  said  there 
were  no  new  operations.  It  was  easy  in  superficial 
articulations  and  difficult  in  others.  Drainage  was  often 
difficult,  but  could,  however,  be  effected  by  canalization  of 
the  joints  and  foci  of  the  aflfection.  If  undiscoverable 
they  must  be  left.  He  laid  great  weight  on  the  use  of  the 
cautery  in  the  operation  of  arthrotomy.  He  admitted 
that  resection  beyond  the  epiphysial  cartilages  yielded 
deplorable  results.  Arthrotomy  was  better  in  youn^ 
children.  Amputation  was  no  shield  against  the  generali- 
zation of  the  tuberculous  condition,  for  the  infiltrated 
glands  were  left  in  every  case. 

Professor  Chiene,  of  Edinburgh,  wished  to  say  a  few 
words  on  this  subject,  on  account  of  the  large  experience 
they  had  of  this  condition  in  the  Edinburgh  schools. 
He  divided  the  cases  for  operation  into  two  classes,  one 
with  sinuses  and  open,  and  one  without  sinuses  and  with 
unbroken  surface.  But  practically  each  joint  must,  he 
said,  be  considered  by  itself.  About  four  of  these  joints 
— ^the  shoulder,  elbow,  knee,  and  ankle — there  was  no 
difference  of  opinion,  the  general  view  being  that  excision, 
with  the  gouge  if  necessary,  was  the  proper  treatment  in 
the  case  of  the  shoulder  and  elbow ;  while  in  the  case  of 
the  knee  it  was  excision  or  amputation ;  and  of  the  ankle 
amputation.  About  the  wrist  he  was  undecided.  Canali- 
zation was,  however,  useful  about  the  wrist 

Professor  Volkmann  said  he  spnoke  unwillingly,  as 
the  opinions  were  so  irreconcilably  different ;  that  much 
mutual  study,  especially  of  Professor  OUier's  paper,  was 
needful  before  deciding.  He  opposed  the  views  of  Pro- 
fessor Chiene.  He  believed  all  scrofulous  joint  disease, 
spinas  ventosae,  etc.,  were  tubercular,  as  experiments  in 
infection  and  observation  of  the  bacillus  proved.  In 
every  case  he  had  found  Koch's  bacilli.  If  that  were 
true,  then  the  treatment  was  clear.  Spontaneous  cure 
might  happen,  but  the  patient  was  always  in  danger  of 
generalization  of  the  condition.  Further,  all  local  recur- 
rences were  due,  not  to  the  system,  but  to  remains  of  the 
foci  left  at  the  operation.  If  all  were  removed,  as  in 
amputation,  then  the  wound  never  became  infected,  but, 
on  the  contrary,  healed  beautifiilly.  Let  them  take  the 
disease  away,  stick  to  no  typical  resections,  but  gouge  and 
cut,  and  do  whatever  will  remove  disease.  A  joint  could 
produce  general  tuberculosis,  but  this  was  rather  excep- 
tional, and  he  thought  the  generalization  must  depend 
on  other  and  multiple  foci — at  least  the  reverse  had  not 
been  proved.  Professor  Oilier  had  not  mentioned  the  Ger- 
man operation.  Arthrotomy  was  not  a  distinctive  word. 
In  Germany  it  signified  wide  opening  of  the  joint,  removal 
of  the  capsule  and  of  the  foci  of  bone  tiU  nothing  re- 
mained around  but  healthy  tissue  ;  and  then  the  reposi- 
tion and  treatment  for  cure  by  first  intention,  antisepti- 
cally.     Such  operations  were  often  huge.   They  involved. 


276 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


in  the  knee,  for  example,  transverse  division  of  the 
patella,  removal  of  the  disease,  or,  it  might  be,  the  front 
and  flaps,  and  an  operation  as  if  for  extirpation  of  a 
tumor.  Professor  Oilier  said  the  operations  were  dan- 
gerous, but  he  (Volkmann)  had  not  found  them  so. 
Professor  Oilier  also  said  that  the  foci  could  be  easily 
lefty  and  he  (Volkmann)  agreed,  but  thought  that,  in 
regard  to  the  knee-joint,  synovial  disease  was  the  most 
common. 

Professor  Tri^lat  agreed  that  most  of  the  affections 
of  joints,  spina  ventosa,  etc.,  were  really  tubercular,  and 
he  was  agreed  with  Volkmann  that  the  tubercular  con- 
dition  could  heal  spontaneously.  He  was  not  so  clear 
about  the  diathesis.  Its  influence  varied.  It  mipht, 
indeed,  have  no  influence  upon  the  wound,  but  it  might 
certainly  determine  the  development  of  other  local 
foci. 

Professor  Volkmann  added  that  out  of  two  hundred 
and  fifty  cases  of  excision  of  the  hip  he  had  seen  only 
five  or  six  where  the  disease  was  not  tubercular. 

Professor  Ollier,  in  his  reply,  said  he  thought  the 
tuberculosis  of  children  differed  from  that  of  adults.  He 
opened  largely,  so  as  to  see  and  remove  all  disease, 
divided  the  ligaments,  and  cut  out  foci.  He  highly  es- 
teemed the  importance  of  the  total  removal  of  the  disease, 
yet  doubted  the  powers  they  had  to  remove  it  He  did 
not  aim  at  immediate  union. 

Dr.  Joseph  W.  Howe,  of  New  York,  showed  a  large 
vesical  calculus  which  he  had  removed  by  the  supra- 
pubic method. 

Dr.  Lauenstein,  of  Hamburg,  gave  a  demonstration 
in  Mekuluz's  operation  for  caries  of  the  foot,  giving  eight 
cases  with  good  results,  four  of  which  had  been  com- 
pletely cured ;  one  only  required  amputation  afterward 
and  one  died. 

Dr.  Sklifossovsky,  of  Moscow,  reported  certain  Rus- 
sian cases. 

Mr,  MacEwen,  of  Glasgow,  read  a  paper  on 

OSTEOTOMY   FOR  GENU   VALGUM, 

in  which  he  related  his  experience  with  the  supra-condy- 
loid  method. 

In  the  discussion  which  followed,  Professor  Ogston, 
of  Aberdeen,  said  he  had  previously  operated  by  a  method 
which  had  been  called  by  his  name,  and  it  was,  he  thought, 
now  time  that  some  conclusions  should  be  arrived  at  con* 
ceming  the  various  existing  methods  of  operating  for  genu 
valgum.  There  had  now  been  sufficient  time  given  and 
sufficient  experience  of  these  operations  to  enable  surgeons 
to  arrive  at  some  definite  understanding  regarding  them. 
He  had  himself  operated  by  MacEwen' s  method  a  con- 
siderable number  of  times,  and  in  such  a  way  as  to  be 
enabled  to  form  a  definite  opinion  on  comparison  of 
these  two  methods.  He  had  operated  on  one  side  of 
the  body  by  his  own  method,  and  on  the  other  side 
by  MacEwen's  operation  exactly  as  described  by  its 
author ;  and  he  was  forced  to  come  to  the  conclusion 
that,  for  simplicity  and  good  results,  MacEwen's  opera- 
tion was  better  than  those  he  had  himself  advocated. 
He  had  not  for  himself  altogether  given  up  his  own 
operation,  chiefly  because  when  one  got  into  the  habit 
of  doing  a  particular  operation,  one  did  not  like  to  throw 
it  overboard  altogether,  being  so  familiar  with  it.  But  he 
had  for  some  years  past  told  his  students  that  MacEwen's 
operation  was  the  best,  and  he  wished  to  make  to  that 
meeting  of  the  congress  a  similar  announcement.  He 
would  advise  every  person  who  wished  to  osteotomize  for 
genu  valgum  to  adopt  it  in  preference  to  his  own.  Re- 
ferringv  however,  to  the  statistics  which  Professor  Mac- 
Ewen had  laid  before  the  congress,  he  said  that  he  had 
found  the  German  surgeons,  even  those  who  at  first  had 
adopted  his  own  operation  enthusiastically,  had  now 
g|iven  it  up  in  favor  of  MacEwen's,  as  the  better  and 
simpler  operation  of  the  two.  That  was  another  reason 
for  adopting  it  himself. 

Professor  Chiene,  of  Edinburgh,  said  that  after  what 


he  had  heard,  he  thought  it  right  to  state  that,  althoagh 
he  could  not  go  to  £e  length  of  Professor  Ogston  in 
throwing  up  his  own  operation  entirely,  still  he  would 
give  MacEwen's  operation  a  fair  trial  on  his  return  to 
Edinburgh.  He  thought  that  in  all  likelihood  he  would 
be  able  to  report  as  favorably  as  Professor  Ogston  had 
done  concerning  it.  It  was,  however,  after  all,  the  pro- 
fession that  were  the  judges  of  the  merits  and  demerits 
of  these  operations,  and  they  had  seen  from  the  statistics 
which  had  been  given  in  that  section,  and  he  also  knew 
it  to  be  the  fact,  that  his  own  operation,  whatever  he 
might  think  of  it  himself,  had  not  commended  itself  to 
the  profession  generally. 

Professor  Schede,  of  Hamburg,  said  he  had  put  for- 
ward an  operation  for  genu  valgum  of  the  tibia  which 
had  gone  by  his  name,  and  he  still  practised  it  in  some 
cases.  But  in  practising  that  operation  he  had  not  done 
so  by  old  ways,  especially  so  often  as  he  had  previously 
done,  but  had  substituted  for  his  own  the  operation  of 
MacEwen,  and  had  by  that  method  obtained  excellent 
results.  He  thought  in  many  instances  that  the  tibia 
was  involved,  and  he  therefore  in  these  cases  performed 
his  own  operation.  But  there  was  no  doubt  that  there 
was  a  large  number  of  pathological  points  showing  that 
the  femur  alone  was  involved  in  a  great  many  cases,  and 
in  some  equally  so  with  the  tibia.  He  differed  from 
MacEwen  in  this  respect  that,  in  doing  his  operation,  he 
did  not  use  several  chisels,  as  was  recommended  in  Mac- 
Ewen's work  on  osteotomy,  but  only  one,  thinking  the 
withdrawal  of  the  instrument  from  the  wound  was  a 
serious  matter,  inasmuch  as  it  sometimes  led  to  a  dis- 
turbance of  the  parts,  and  to  a  difficulty  of  reintroduc- 
tion  of  the  instrument.  But,  along  with  all  German 
surgeons,  he  accepted  MacEwen's  operations. 

Mr.  Bryant,  of  London,  said  he  thought  the  section, 
after  hearmg  what  had  been  said  by  these  diree  great  men, 
would  scarcely  find  it  necessary  to  discuss  further  the 
relative  value  of  these  operations.  They  would  all  agree 
that  MacEwen's  operation  had  been  proven  by  the 
statistics  adduced,  and  also  by  the  fact  that  the  authors 
of  the  other  methods  had  now  practically  given  them  up. 
He  must  say  for  himself  that  he  had  used  MacEwen's 
operation  many  times  with*  very  great  success,  and  it  was 
gaining  ground  where  previously  Ogston's  operation  had 
been  practised.  He  was  sure  the  section  would  endorse 
what  had  been  said  about  MacEwen's  operation  being 
the  best  one,  but  he  could  not  sit  down  without  express- 
ing the  very  great  pleasure  he  felt  at  the  manner  in  which 
the  other  gentlemen  had  given  up  what  he  might  call 
their  pet  operations.  Professor  Ogston  had  done  this 
with  the  greatest  possible  grace,  and  he  (Mr.  Bryant)  was 
sure  the  section  would  award  him  and  the  others  a  vote 
of  thanks  for  the  manner  in  which  they  had  acted. 

Dr.  V.  Robin,  of  Lyons,  next  read  a  paper  "  On  a 
New  and  Perfected  Method  of  Osteoclasis  for  Genu 
Valgum,"  with  eighty  photographs  of  patients  operated 
on  after  this  new  system. 

Mr.  W.  Adams,  of  London,  read  a  paper  demonstrat- 
ing a  series  of  photographs  taken  from  cases  of 

dupuytrkn's  finger  contraction. 

He  took  occasion  to  correct  what  he  said  was  in  the 
books,  the  anatomically  imperfect  description  of  the  fascia 
and  its  relation  to  the  tendons  of  the  hands,  with  a  special 
view  to  the  pathology  of  this  afiection.  His  own  opera- 
tion for  the  cure  of  the  condition,  which  he  described  at 
length,  he  designated  as  a  happy  combination  of  the 
tenotomy  of  Dupuytren  first  described  in  1831  with  the 
subcutaneous  surgery  of  Stromeyer ;  its  object  being  to 
deal  with  the  fascia  at  fault,  as  well  as  the  tendons.  As 
to  the  pathology  of  the  condition  he  still  adhered  to  his 
own  view  that  it  essentially  depended  on  a  chronic  gouty 
thickening  of  the  fascia. 

In  answer  to  a  question  as  to  the  return  of  the  condi- 
tion after  operation,  he  said  that  in  his  own  cases  he  had 
found  no  severe  ones  of  return  and  bad  never  seen  much 


September  6,  1884.  J 


THE  MEDICAL  RECORD. 


277 


tendency  to  it.     The  great  majority  remained  free  from 
it  for  life. 

THE  LISTERIAN   ANTISEPTIC   TREATMENT. 

In  the  absence  of  Professor  Sir  J.  Lister,  of  London, 
who  was  to  have  opened  the  discussion  of  the  present  form 
of  his  treatment.  Professor  Esmarch  introduced  the 
subject  with  a  paper,  f  He  began  by  expressing  regret 
at  the  absence  of  Lister,  the  illustrious  master  and 
teacher  of  them  all.  He  then  went  on  to  describe  the 
method  of  treatment  now  followed  in  his  own  clinique. 
The  aim  was  the  avoidance  of  suppuration  in  any  case, 
and  the  leaving  of  the  wound  undisturbed.  This  was 
best  done  by  a  permanent  dressing  preventing  the  en- 
trance of  germs.  The  postulates  were,  first,  exact 
luemostasis ;  second,  the  avoidance  of  cavities  in  the  in- 
terior of  the  wounds ;  third,  drainage,  artificial  ischsemia, 
application  of  multitudes  of  catgut  ligatures  on  great  and 
small  vessels,  and  bandage  applied  before  removal  of 
toomiquet,  support  of  all  the  deep  parts  by  sutures,  curl- 
ing in  the  edges  of  the  skin,  and  pressure.  The  drainage- 
tube,  as  preventing  healing,  was  not  now  used  by  him, 
but  openings  were  left  for  escape  of  exudation. 

Asepsis  was  minutely  studied  The  bandage  strips 
were  sterilized  by  dry  heat  and  sublimate.  The  spray 
was  used  only  before  operation,  so  as  to  disinfect  the  air 
in  the  room.  During  one  operation  distilled  water  with 
salt  only  of  specific  gravity  of  the  blood,  was  used  for 
irrigation,  but  at  the  end  sublimate  was  employed 

Occasionally  other  antiseptics,  as  iodoform,  were  used. 
For  bandage  material,  loose,  absorbent,  soft  matter  was 
needed.  Peat  was  useful  in  pillows  f  no  Mackintosh),  dip- 
ped in  carbolic  lotion.  Then  immooilization  of  the  parts 
was  obtained  by  glass  splints  till  healing  by  first  intention 
occured  The  latter  took  from  eight  to  ten  or  fourteen 
days  to  five  or  six  weeks  after  operations. 

Dr.  Mostig-Moorhof  advocated  iodoform  treatment 
of  wounds,  and  said  he  operated  with  no  other  antiseptic 
He  used  cold  water  during  operations.  There  was  no 
irritation  and  certain  asepsis.  Iodoform  prevented  trans- 
udation of  the  white  blood-cells.  He  narrated  a  case  of 
traumatic  septic  gangrene  extending  above  the  knee, 
where  yet  the  knee-joint  was  found  aseptic  at  the  post- 
mortem examination.  Iodoform,  also,  was  a  substance 
that  diminished  pain. 

Dr.  Schede  said  that  the  principles  of  antiseptics  re- 
mained unaltered,  though  the  methods  had  changed. 
After  his  training  in  Halle,  when  called  to  Berlin,  he 
found  Lister's  method  perfect  in  its  results.  But  on  suc- 
ceeding to  Marten,  at  Hamburg,  he  had  never  had  perfect 
success  with  Listerism ;  he  was  now  unable  quite  to  ex- 
clude accidental  wound  disease  from  his  cases.  The 
hospital  was  old,  and  in  many  respects  undesirably  ar- 
ranged and  situated  He  tried  iodoform  without  good 
results.  On  the  reports  as  to  the  substance  he  had  re- 
solved to  try  the  sublimate  dressing,  and  now,  after  ex- 
perience, had  got  with  it  brilliant  results.  Erysipelas  at 
once  disappeared,  not  one  case  had  since  occurred  under 
the  dressing  in  his  clinique.  There  was  neither  septicae- 
mia, pyaemia,  nor  irritation.  Wounds  had  occurred ;  but 
they  were  dry,  and  showed  a  great  tendency  to  heal  by 
first  intention.  His  impression  was  that  it  was  equalled 
by  no  other  plan.  He  now  used  a  solution  of  i  to  500, 
and  had  no  case  of  poisoning  with  these  strengths. 
SoDoetimes,  however,  there  was  tenesmus  of  the  rectum. 
Children  especially  tolerated  the  sublimate  wonderfully. 
In  the  final  dressing  he  tried  to  keep  everything  dry. 

Dr.  Mikuucz  did  not  agree  with  either  Moorhof  or 
Schede.  In  his  clinique,  which  was  much  worse  than 
Schede^s,  he  had  had  no  erysipelas  with  iodoform.  But 
iodoform  could  not  be  used  alone.  Other  soluble  sub- 
stances must  be  applied  where  its  insolubility  prevents 
its  fulfilling  the  indications.  He  disinfected  with  carbolic 
or  sublimate  solution,  and  had  no  spray.  In  the  vagina, 
etc.,  he  plugged  the  canal  with  iodoform  gauze ;  in  rec- 
tum, stitched  one  side  and  the  upper  end  of  the  sphincter. 


and  had  no  drain,  even  where  the  peritoneum  was  opened. 
Poisoning  occurred  only  from  excessive  use. 

Professor  Neudorfer,  of  Vienna,  said  the  aim  of 
antiseptic  surgeons  was  the  same,  but  the  methods  varied, 
and  must  of  necessity  vary,  almost  to  infinity.  Our 
knowledge  was  limited ;  they  knew  that  decompositions 
occurred,  but  nothing  as  to  how,  how  far,  or  how  intensely 
they  did  so.  Each  surgeon  was  satisfied  with  his  own 
plans  and  really  got  good  results.  But  statistics  were  not 
of  much  value.  They  must  study  rather  in  the  direction 
of  sepsis.  Sepsis  needed  water  ;  therefore  he  never  used 
water  in  his  wound  treatment.  He  used  no  sponges,  but 
a  dry  towel  crumpled  together  to  wipe  up  the  blood  and 
wring  it  out.  The  serum  of  the  blood  was  a  matter  that 
should  be  studied ;  oxidation  and  deoxidation  were  im- 
portant processes.  Therefore  he  used  in  his  wounds 
peroxide  of  hydrogen  and  had  found  singularly  good  re- 
sults. 

Professor  Buchanan,  of  Glasgow,  said  the  discussion 
of  antiseptics  without  Lister  was  like  the  play  of  Hamlet 
with  the  Prince  of  Denmark  left  out.  As  a  representa- 
tive of  Scotland,  the  home  of  antiseptic  surgery,  a  col- 
league of  Lister,  and  one  who  had  witnessed  his  earliest 
results,  he  wished  to  contribute  a  few  words  to  the  dis- 
cussion. He  agreed  that  the  principles  of  antiseptics 
were  always  the  same,  though  the  methods  might  vary ; 
and  he  described  the  method  now  employed  in  Glasgow. 

Dr.  Schelkley,  of  America,  said  the  tendency  to  dis- 
ease, sepsis,  etc.,  was  different  in  different  races.  His 
practice  had  been  in  the  tropics.  First  he  used  thorough 
Listerism,  but  never  got  healing  by  first  intention,  but 
always  slight  surface  sloughing  and  healing  by  second  in- 
tention ;  yet  no  pus  and  no  fever.  He  then  changed  his 
plan,  ceased  to  spray,  and  irrigated  during  the  operation 
with  salicylic  acid  or  sublimate,  and  iodoform  dressings 
or  boric  lint.  Salicylic  and  iodoform  gave  the  best  re- 
sults, yet  he  did  not  get  '*  first  intention." 

Professor  KoeberlA,  of  Strassburg,  said  that  since 
1884  he  had  u§ed  only  linen  to  wipe  his  wounds,  and 
had  had  no  case  of  erysipelas  among  his  operations  since 
then.  He  claimed  to  have  better  results  than  Schede ; 
even  his  ovariotomies  were  ail  cured. 

Professor  Plum  said  that  the  Danish  surgeons  agreed 
entirely  with  the  German,  but  he  was  prevented  from 
agreeing  with  Esmarch's  plan  on  account  of  its  cost. 
The  chief  antiseptics  were  soap  and  brush,  and  by  simple 
means  much  might  be  done. 

Professor  Tr^lat  said  he  had,  three  years  ago,  laid 
down  the  following  lines :  Make  the  wound  of  a  form  suita- 
ble for  healing  by  first  intention,  and  perfectly  adapted. 
Leave  no  foreign  body  in  the  wound,  either  mechanical 
or  septic  Antiseptics  did  not  exist  in  some  countries — 
not  on  the  top  of  Chimborazo-^and  half-educated  Ameri- 
cans did  wondrous  operations  on  negroes.  The  prin- 
ciples of  antiseptics  were  not  altered ;  the  practice  was 
being  perfected.  He  pointed  out  the  incomparable  merit 
of  Lister,  who  had  given  them  the  principles ;  whatever 
the  methods  might  become  was  of  little  importance.  He 
(Tr^lat)  used  the  iodoform  gauze-— deeply  as  plugs,  and 
superficially  as  required;  and  made  a  large  cushion 
pressed  with  elastic  bandages  to  the  wound,  changing 
the  dressings  on  the  fifteenth  day. 

Dr.  Mostig-Moorhof  challenged  Mikulicz  to  say 
that  he  had  ever  tried  a  thorough  iodoform  dressing; 
and  if  not,  whence  he  knew  that  iodoform  required  other 
antiseptics  to  supplement  its  use.  At  the  time  that 
Schede  had  tried  iodoform  there  was  an  epidemic  of  ery- 
sipelas all  over  Europe,  and  if  he  would  try  it  now  he 
would  get  better  results. 

Professor  Plum  closed  the  debate  with  a  compliment 
to  Lister,  which  was  received  with  great  applause. 

PHELPS'    OPERATION    FOR   CLUB-FOOT. 

Dr.  a.  M.  Phelps,  of  Chateaugay,  N.  Y.,  detailed 
cases  and  showed  photographs  of  club-foot  which  he 
had  treated  by  a  new  operation,  consisting  of  tenotomy 


278 


THE  MEDICAL  RECORD. 


[September  6,  1884. 


of  the  tendo  Achillis,  incision  of  the  sole  of  the  foot  op- 
posite Chopart's  joint,  cutting  of  the  tendons  and  tissues 
down  to  the  bone,  leaving  only  the  external  plantar  ar- 
tery and  nerve.  Afterward  the  foot  was  fixed  in  position 
by  wire  hooks  of  adhesive  plaster  laced  together.  It 
had  been  performed  in  children  five  years  of  age  or  therea- 
bouts. 

Profbssor  Studsgard,  of  Copenhagen,  read  a  paper 
on 

THE   TREATMENT  OF   STRICTURES   OF  THE  GBSOPHAGUS. 

He  had,  he  said,  taken  great  interest  in  this  question 
-and  in  the  statistics  of  it.  Where  dilatation  failed,  gas- 
trotomy,  he  thought,  might  be  had  recourse  to,  and  the 
stricture  dilated  even  from  that.  In  his  practice  in  cav- 
ernous stricture  one  case  had  survived  for  seven,  one  for 
•six,  and  one  for  five  months  after  the  operation.  In  four 
of  stricture  from  cicatrix,  two  died  arid  two  survived.  In 
pressing  cases,  where  the  gastrotomy  could  not  be  per- 
formed in  two  stages  on  account  of  nutrition  of  the  pa- 
tient, he  thought  that  a  minute  opening  should  be  made 
at  once,  and  close  sutures  should  be  axlopted.  Langen- 
bach  made  a  capillary  puncture  for  this  purpose.  He 
recommended,  as  a  general  rule,  that  the  operation  should 
be  done  in  one  sitting,  the  sutures  not  including  mucous 
membrane.  The  latter  was  so  loose  that  there  was  no  fear 
•of  including  it.  He  referred  to  a  patient  upon  whom  he 
had  operated  for  stricture  of  the  oesophagus,  probably  su- 
perficial, two  and  a  half  years  ago,  who  now  fed  himself 
by  a  drainage-tube  doubly  bevelled  at  the  point,  and  was 
in  a  perfect  state  of  health. 

Professor  Hjorth,  of  Christiania,  adduced  a  case  of 
stricture  from  contraction  after  swallowing  an  alkali.  No 
sound  could  be  passed  below  the  cricoid  cartilage,  and 
there  was  difficult  swallowing  by  slow  efforts.  Gastrotomy 
was  performed,  with  oesophageal  catheterism  and  elec- 
trolysis applied  at  the  part  and  a  specially  constructed 
i>ougie.  The  positive  pole  was  on  the  right  side  of  the 
neck ;  first  five,  then  ten,  and  finally  fifi^een  cells  were  apt 
plied,  and  after  an  hour  the  bougie  went  through  suddenly. 
Stricture  three  ctm.  long.  No  bad  results  followed,  and 
a  repetition  of  procedure  was  gone  through  twelve  days 
later.  The  patient  could  now  swallow,  and  soon  flesh  and 
solids  were  swallowed,  and  a  No.  19  bougie  (Charriire) 
went  through  from  below  and  above.  The  largest  bougies 
jiow  passed,  and  the  patient  was  well  nourished  A  fort- 
night later  he  ^Professor  Hjorth)  closed  the  gastric 
vfistula  by  a  vivincation  operation  and  a  bridge  trans- 
planted b^  glissement.  For  such  catheterism  the  car- 
'diac  openmg  must  be  large  enough  to  admit  the  finger. 
The  cardiac  orifice  was  found  without  much  difficulty, 
especially  if  a  curved  staff  bougie  was  first  passed  up. 
To  cure  the  gastric  juice  digestion  of  the  wound  after 
the  first  operation,  he  found  the  bismuth  dressing  valu- 
able. He  therefore  advised  gastrotomy  and  treatment 
irom  below  for  oesophageal  cicatricial  stricture,  and  sec- 
ondly the  use  of  electrolysis. 

Professor  Verneuil  once  saw  a  stricture  from  alco- 
hol There  was  no  malignancy  and  no  caustics  in  the 
xase,  alcohol  being  the  sole  cause  of  the  condition.  He 
approved  of  the  conclusion  of  the  operation  in  one  sit- 
ting. He  sutured  closely  and  opened  very  minutely, 
about  the  size  of  a  No.  to  English  catheter,  and  nothing 
escaped.  The  sound  was  lodged  and  stitched  in,  and  no 
harm  ever  resulted,  the  antiseptic  dressing  being  ap- 
plied. So  long  as  the  patients  could  swallow,  and  a  fine 
sound  be  passed,  dilatation  was  the  proper  treatment, 
especially  by  the  permanent  lodgment  of  a  red  nibber 
sound ;  and  the  patients  could  be  brought  to  go  about 
all  their  affairs  with  this  sound  in,  it  being  withdrawn 
when  they  wished  to  swallow. 

Professor  Sch5nborn  warned  the  section  against 

gastrotomy  when  the  patient  had  bronchial  symptoms,  as 

these  probably  indicated  the  involvement  of  a  bronchus. 

He  approved  of  the  operation  being  done  in  two  sittings. 

'  The  piece  of  stomach  fixed  in  the  wound  had,  however,  | 


in  some  of  his  cases,  become  spontaneously  perforated 
from  deficient  nutrition. 

M.  Petit,  of  Paris,  gave  some  very  elaborate  sta- 
tistical  details  as  to  155  operations,  with  two  per  cent 
cures  and  twenty-seven  per  cent,  deaths.  This  was  be- 
fore antiseptics  were  employed. 

Mr.  Thornton,  of  I^ondon,  spoke  of  one  case  from 
hair  swallowing.  He  proceeded  to  make  a  median  in. 
cision,  opening  the  stomach  oy  transfixion,  the  peri- 
toneum being  protected  by  packed  carbolized  sponges. 
Removal  of  the  mass  was  affected,  and  the  stomach 
sutures  were  made  in  a  double  row,  deep  and  superficial. 
There  was  subsequently  right  parotitis  and, incision,  but 
no  pus.  Left  parotitis  was  treated  by  belladonna  cata^ 
plasms.  He  found  a  sponge  had  been  left  in  the  peri- 
toneum, chiefly  by  localized  pain  and  counting  the 
sponges.  On  opening  the  abdomen  to  remove  the 
sponge  he  found  the  stomach  wound  healed. 

Mr.  Bryant,  of  London,  said  he  found  one  row  of 
sutures  enough.  He  described  the  minute  opening  of 
the  stomach  adopted  by  him.  His  colleagues  in  Guy's 
Hospital  had,  in  six  operations,  used  clamping,  drawing 
out  the  stomach  by  two  rubber-shield  forceps,  and  used 
no  sutures.  One  patient  subsequently  married  and  had 
a  child.  In  her  case,  two  and  a  half  years  after  the 
operation,  she  suddenly  found  she  could  swallow  liquids 
and  solids,  such  as  bread,  fish,  and  minced  meat.  She 
still  had  the  fistula,  and  Mr.  Bryant  had  advised  her  to 
leave  it  alone,  as  she  was  quite  dry,  even  after  a  laige 
meal. 

Professor  Sklifporoswskv  advised  cesophagotomy, 
and  subsequent  dilatation  through  the  wound. 

Professor  Hjort  said  fifteen  elements  were  neces- 
sary in  electrolysis. 

M.  Ollier  advised,  in  preference  to  operations, 
wherever  possible,  the  use  of  the  minutest  whalebone 
bougies,  one-half  mm.  in  diameter,  and  the  treatment  on 
the  principle  which  Syme,  of  Edinburgh,  had  enunciated 
for  the  urethra,  viz.,  that  no  case  was  impermeable.  He 
admitted  this  was  sometimes  excessively  difficult,  but  it 
was  always  possible,  and  then  dilatation  was  often  ex- 
tremely easy. 

SURGICAL   ANifiSTHESIA, 

Dr.  O.  Wanscher,  of  Copenhagen,  in  a  paper  on  this 
subject,  dealt  with  anaesthesia  by  irectal  insufflation  of 
ether  vapor.  PirigofPs  first  attempts  were  not  attended 
with  good  results.  Duping  and  others  tried  the  method, 
but  it  fell  into  disuse.  Two  years  ago  he  (Dr.  Wanscher) 
a^ain  took  up  the  subject,  and  his  experience  had  con- 
vinced him  that  it  should  be  revived,  especially  in  aid 
of  other  methods,  so  as  to  improve  the  respiratory  organs. 
There  must  be  preliminary  cleansing  of  the  rectum,  and 
insufflation  of  the  vapor  through  a  warmed  reservoir. 
He  narrated  cases. 

Dr.  Jennings,  of  London,  said  that  unless  the  epi- 
glottis were  drawn  forward  by  a  sutur6  put  through  it,  it 
fell  down  during  respiration,  and  unless  this  were  done 
tracheotomy  should  not  be  performed.  In  experiments  on 
dogs  with  chloroform,  the  epiglottis  was  secured  forward, 
the  tongue  drawn  forward,  and  the  chloroform  admin- 
istered until  the  heart  stopped,  and  more  was  then  given 
until  artificial  respiration  failed  to  restore  its  action. 
Then  the  jugular  vein  was  opened,  a  canula  put  in  tow- 
ard the  heart  side,  and  a  saline  fluid  injected,  while 
bleeding  from  the  peripheral  end  was  allowed  to  go  on. 
The  dog  recovered,  but,  from  the  amount  of  blood  lost, 
was  likely  to  die.  He  then  injected  the  quantity  of 
blood  corresponding  to  the  excess  of  blood  lost,  and  the 
animal  recovered. 

MASSAGE. 

Dr.  Tubelerdowsky,  of  Berlin,  in  a  paper  on  this  sub- 
ject, said  he  knew  a  lady  in  Berlin  who  took  a  pain  in  her 
knee  every  time  her  husband  had  an  attack  of  angina 
pectoris. 

Dr.  David  Prince,  of  Jacksonville,  III,  read  a  paper 


September  6,  1884.] 


THE  MEDICAL  RECORD. 


279 


upon  **  Palatoplasty  with  a  New  Instrument,"  and  demon- 
strated his  needles. 

Professor  Moore,  of  Rochester,  N.  Y.,  read  a  com- 
munication on 

LUXATION  OF  THE   ULNA   IN    CONNECTION   WITH   COLLSS' 
FRACTURE. 

Id  this  fracture,  he  said,  there  was  also  an  accompanying 
displacement  of  the  lower  end  of  the  radius.  After  the 
radius  gave  way  the  attachments  of  the  triangular  cartilage 
and  internal  lateral  ligament,  acting  on  the  styloid  process, 
broke  it  off,  or  were  themselves  torn.  In  continuation  of 
the  force  the  ulna  was  shot  on,  and,  penetrating  the  fascia 
and  skin,  might  become  compound.  He  advised  reposi- 
tion under  chloroform,  with  subcutaneous  division,  if 
needful,  in  recent  cases.  In  old  standing  cases  he  re- 
sected the  lower  end  of  the  ulna.  His  method  of  re- 
duction was  by  flexion  and  pronation  over  the  knee,  and 
he  retained  it  with  finser  and  thumb.  He  then  laid  a 
slender  splint  and  rolled  bandage,  three-fourths  of  an  inch 
in  diameter,  and  fixed  it  by  a  strip  of  plaster  drawn  up  as 
I  tighdy  as  possible.  The  hand  was  allowed  to  drop,  and 
!  a  sling  of  bandage  the  length  of  the  plaster  strap  put  over 
the  spot. 

DiL  Oscar  Wanscher,  of  Copenhagen,  read  a  paper 
on  the 

TORSION  OF  LAltGE   ARTERIES  NEAR  THEIR  BIFURCATION. 

He  had,  he  said,  had  no  cases  of  his  own,  but  he  had  ex- 
perimented on  animals  on  torsion  and  refoulement,  and 
he  demonstrated  the  results. 
\  Professor  Plum,  assuming  the  chair,  thanked  the 
audience,  the  presidents,  the  speakers,  and  the  bureau, 
and  bade  all  au  revoir  d  Washington  en  1887. 

(To  be  oontmued.) 


SHALL  ARMY  SURGEONS  PRACTISE  OUTSIDE 
THEIR  POSTS? 

To  THs  Editor  op  Thb  Mbmcal  Rxoobd. 

Sir  :  The  accusation  of  unfairness  from  one  who  hides 
himself  behind  the  wand  of  the  god  of  dissimulation,  etc., 
falls  flat ;  and  the  letter  he  writes  to  prove  it  fails  lament- 
ably. The  mental  obtuseness  which  prevented  my 
seeing  things  as  some  medical  officers  see  them,  still 
prevents  me  firom  acknowledging  the  fairness  of  this  ac- 
cusation. The  '^  extract  from  a  letter''  simply  begs  the 
question. 

1  shall  be  more  than  glad,  if  it  can  be  shown  that  any 
statement  in  my  letter  is  not  strictly  just  and  fair.  The 
"extract"  simply  proves  that  the  custom  of  which  I 
complain  dates  farther  back  than  I  had  supposed,  from 
what  had  been  told  me  by  *'  officers  and  gentlemen  "  in 
die  army.  That  does  not  make  the  custom  any  more 
proper,  nor  does  it  prove  any  statement  of  mine  unfair. 
I  see  nothing  in  this  *'  extract"  to  convince  any  one  that 
it  is  fair  and  honorable  for  an  adequately  salaried  army 
surgeon  to  employ  most  of  his  time  in  practising  outside 
his  post,  when  by  so  doing  he  is  necessarily  brought  into 
competition  with  physicians  who  have  not  the  advantage 
of  an  assured  and  regular  income  outside  of  their  prac- 
tice. I  must  reiterate,  that  it  is  unfair  and  unjust  com- 
petition; and  no  amount  of  '* extract"  is  going  to  alter 
that  FACT. 

The  argument  that  it  would  be  ungracious  to  deprive 
a  suffering  public  from  consulting  army  surgeons  looks 
pretty,  but  is  unmitigated  bosh.  If  that  will  apply  to 
any  one  branch  of  the  service,  it  must  apply  logically  to 
aU  others.  Imagine  a  suffering  public  seeking  legal  ad- 
vice from  the  law  officers  of  the  Government  in  ordinary 
legal  matters.  Imagine  also  the  frame  of  mind  of  civil 
attorneys-at-law  et  al.  under  such  circumstances. 
With  all  due  respect  I  would  submit  that  the  average 


army  surgeon  who  does  outside  practice,  is  actuated 
more  by  a  strong  desire  for  the  accruing  fees  than  by 
any  purpose  of  "  becoming  familiar  with  disease  under 
all  circumstances,"  etc.,  however  beautiful  and  lofty  such 
a  purpose  might  be.  I  am  of  the  opinion,  rather,  that  the 
purpose  kept  steadily  in  view  is  mainly  in  regard  to  that 
**  which  relates  exclusively  to  (the  army  surgeon's)  private 
interests.*' 

Notwithstanding  the  ^*  extract  from  a  letter  "  with  its 
specious  argument,  I  am  still  of  the  belief  that  it  is  not, 
and  has  not  been,  the  general  custom  for  army  surgeons 
to  do  or  seek  outside  practice  except  under  exceptional 
circumstances,  which  do  not  obtain  here.  If  at  small 
posts  ''it  has  been  found  much  more  satis&ctory,  for 
military  reasons,  to  have  the  duties  of  post  surgeons  per- 
formed by  a  regular  medical  officer,"  it  would  be  equally 
satisfactory,  for  civil  reasons,  that  he  should  confine  him- 
self to  his  appointed  duties,  and  not  encroach  on  what  I 
claim  is  no  legitimate  neld  for  operation.  Stripped  of  all 
sentiment,  the  army  surgeon  is  a  public  servant  and  is 
paid  for  his  services.  If  he  has  plenty  of  time  to  devote  to 
outside  practice,  then  he  is  paid  too  much  for  what 
little  service  he  does  render,  and  therefore  receives  more 
than  he  is  justly  entitled  to ;  or  if  it  is  proper  to  practise 
in  the  region  about  him,  to  the  end  that  he  may  not  grow 
nisty  and  thereby  inflict  injury  on  the  service  generally^ 
then  it  is  not  proper  for  him  to  receive  fees  for  so  doing, 
since  by  his  own  admission  he  is  only  striving  to  main- 
tain his  standard  of  excellence. 

The  attempt  in  this  ''extract"  to  throw  upon  us  phy- 
sicians the  odium  of  trying  to  prevent  army  surgeons 
from  familiarizing  themselves  with  the  "maladies  pre- 
vailing through  the  country  and  among  citizens  generaUy," 
will  fail  simply  because  it  does  not  contain  the  elements 
of  common-sense. 

It  will  require  more  proof  than  is  adduced  by  "  Cadu- 
ceus*'  to  convince  any  one  that  practising  outside  of 
posts  by  army  surgeons /<?r /ay  is  proper,  while  they  are 
on  full  salary  from  the  Government. 
Very  truly  yours, 

John  G.  Stanton,  M.D. 

New  London,  August  ao*  1884. 


OBESITY  AND  THE  SEXUAL  FUNCTION. 

To  THB  EDfTOK  OP  T^  BiBDICAL  RSOOXH. 

Sir  :  In  your  issue  of  this  date,  at  the  bottom  of  the  first 
column  of  page  183,  I  notice  an  explanation  of  the  fact 
that  women  are  more  subject  to  obesity  than  men  which 
strikes  me  as  very  odd.  It  is  contained  in  these  words : 
**The  lesser  activity  of  their  sexual  life."  I  feel  that  I  am 
not  alone  in  failing  to  understand  the  meaning  of  this 
phrase.  You  surely  do  not  mean  that  men  copulate 
more  frequently  than  women ;  and  yet  what  else  can  you 
mean  ?  Yours  respectfully, 

Youthful. 

August  16,  1884. 

[We  refer  to  the  generally  accepted  fact  that  women, 
as  a  rule,  experience  sexual  feelings  less  intensely  and  less 
frequently  than  men,  and  to  the  fact  that  the  mass  of  re- 
spectable women  masturbate  less  and  have  intercourse 
less  often  than  men. — Ed.] 


The  Rights  of  a  Defendant  on  Trial  for  Rape. 
— A  court  in  a  Western  State  has  recently  held  that,  upon 
the  trial  of  a  person  indicted  for  rape  upon  a  female 
child,  evidence  is  admissible  of  the  answers  given  by  the 
girl,  two  or  three  days  after  the  alleged  injury,  to  the  ques- 
tions of  her  mother,  induced  by  the  girl's  singular  de- 
meanor. A  hypothetical  question  put  to  a  physician, 
whether  in  his  opinion  the  facts  assumed  would  constitute 
rape,  is  altogether  improper,  being  a  demand  for  his  legal 
instead  of  his  medical  knowledge.  Yet,  if  he  gives  a  cor- 
rect answer,  the  impropriety  of  the  question  is  no  ground 
for  a  new  trial 


28o 


THE   MEDICAL  RECORD. 


[September  6,  1884. 


I^rms  MexoB. 


Official  List  ef  Changis  in  the  Statums  and  DuOis  of  Officers 
serving  in  the  Medical  Department y  United  States  Army, 
from  August  23  to  August  30,  1884. 

Head,  John  F.,  Colonel  and  Surgeon.  Granted  leave 
of  absence  for  four  months.  S.  O.  20 j,  A.  G.  O.,  Au- 
gust 27,  1884. 

WooDHULL,  A.  A.,  Major  and  Surgeon.  Detailed  as 
member  of  Medical  Examining  Board  at  U.  S.  Military 
Academy,  West  Point,  N.  Y.,  vice  Captain  R.  H.  White, 
relieved.  Upon  adjournment  of  the  Board  to  return  to  his 
proper  station.     S.  O.  201,  C.  S.,  A.  G.  O. 

LiPPiNCOTT,  Henry.  Promoted  Major  and  Surgeon, 
to  rank  from  August  17,  1884,  vice  Woodward,  deceased. 

Bartholf,  J.  H.,  Captain  and  Assistant  Surgeon.  Re- 
lieved from  duty  in  Department  of  the  Columbia,  and  to 
report  in  person  to  Commanding  General,  Department 
of  Texas,  for  assignment  to  duty.  S.  O.  199,  A.  G.  O., 
August  25,  1884. 

FiNLBY,  J.  A.,  Captain  and  Assistant  Surgeon.  The 
leave  of  absence  granted  him  in  S.  O.  91,  C.  S.,  Depart- 
ment of  Texas,  extended  two  months.  S.  O.  198,  A.  G. 
O.,  August  23,  1884. 

Taylor,  M.  £.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  four  months,  to  take  effect 
on  arrival  of  a  Medical  Officer  at  David's  Island,  N.  Y., 
to  replace  him.     S.  O.  200,  A.  G.  O.,  August  26,  1884. 

Gibson,  R.  J.,  First  Lieutenant  and  Assistant  Sur- 
geon. Relieved  from  duty  in  Department  of  the  Mis- 
souri and  ordered  to  Department  of  California  for  duty. 
S.  O.  202,  A.  G.  0-,  August  28,  1884. 

DiETZ,  William  D.,  First  Lieutenant  and  Assistant 
Surgeon.  Relieved  from^duty  at  the  Military  Academy, 
West  Point,  N.  Y. ,  and  ordered  to  the  Department  of  the 
Missouri  for  duty.  S.  O.  202,  A.  G.  O.,  August  28, 
1884. 

McCaw,  Walter  D.  Appointed  Assistant  Surgeon, 
with  rank  of  First  Lieutenant,  to  date  from  August  20, 
1884. 


pcedical  Items. 


CoiiTAGious  Diseases — ^Weekly  Statement. — ^Re- 
port  of  cases  and  deaths  from  contagions  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  August  30,  1884 : 


Week  Ending 


Gmm. 

August  23,  1884 
August  30,  1884 

Deatkt. 

Xugust  23,  1884 
August  30,  1884 


Stigmata  Maidis  in  Gonorrhoea. — Dr.  Bennett  says 
that  he  has  had  unusual  success  in  the  treatment  of  gonor- 
rhoea by  fluid  extract  of  com  silk  (stigmata  maidis).  To 
him  the  treatment  was  quite  novel,  while  it  has  been  a 
great  comfort  to  the  patients,  who  were  entirely  relieved 
within  a  week,  and  very  often  in  three  days.  He  de- 
pended alone  upon  the  com  silk,  and  of  course  made  no 
error  in  attributing  success  to  that  drug.  A  half-teaspoon- 
ful  to  a  teaspoonful  of  the  fluid  extract  three  times  a  day 
will  prove  eflectual  in  male  or  female. — Therapeutic 
Gazette, 


"  Death  owing  to  visitation  of  Providence  under  sus- 
picious  circumstances,"  is  a  coroner's  verdict  in  Muns- 
ten 

A  Curious  Freak  of  Nature. — Dr.  Marvin,  Rea. 
dent  Physician  of  the  Saginaw  Hospital,  East  ^naw 
Mich.,  sends  us  the  account  of  a  very  curious  occurrence! 
"  A  few  days  ajgo,"  he  writes,  "  while  Dr.  Ross,  Surgeonl 
in-Chief  of  Saginaw  Hospital,  was  attending  a  case  of  ob- 
stetrics, he  met  with  a  peculiar  freak  of  nature.  After 
the  child  was  delivered  and  the  umbilical  cord  severed, 
he  found  a  shred  of  membrane  passing  into  the  child's 
mouth  and  seemingly  fast  there ;  on  following  it  to  the 
vulva  on  the  mother  he  found  it  was  attached  internally. 
He  severed  the  shred,  and  by  further  examination  found 
that  it  passed  into  the  child's  moutlf  behind  the  soft  pal- 
ate  and  out  through  the  left  nostril,  and  was  tied  in  a 
slip-knot  around  the  part  that  entered  the  mouth.  After 
the  secundines  were  removed  the  other  end  was  followed 
to  its  attachment,  which  was  on  the  placenta  near  the 
umbilical  cord.  It  was  there  found  it  started  in  a  shred 
about  three  Angers  in  width,  and  diminished  until  it  was 
about  one-fourth  of  an  inch  wide  where  it  entered  the 
mouth ;  from  that  point  it  kept  up  a  uniform  width  to  its 
end"  Dr.  Marvin  encloses  to  us  the  specimen,  so  that 
we  can  verify  his  description. 

The  Question  of  the  Florida  Climate.— Dr.  R. 
A.  Lancaster,  of  Gainesville,  FUu,  writes  us  a  letter  in 
defence  of  the  Gainesville  and  the  Florida  climate,  sup- 
plementing; Dr.  Bradner*s  letter.    After  some  rather  per- 
sonal criticism  of  Dr.  Boyland's  views,  he  concludes: 
"  That  many  consumptives  do  die  in  Florida,  however, 
all  will  admit,  and  I  think  their  physicians  are  to  be  cen- 
sured  for  sending  them  away  from  the  comforts  of  home 
when  they  are  so  evidently  beyond  sdl  hope  of  recovery; 
but  that  Uie  lives  of  many  consumptives  have  been  pro- 
longed, and  many  catarrhs  and  cases  of  bronchitis  of 
long  standing  have  been  permanently  cured,  is  a  fact 
that  no  honest  observer  will  deny.     This  'Question  of 
the  Florida  Climate '  is  one  of  paramount  interest,  not 
only  to  the  profession,  but  to  countless  invalids  through- 
out the  United  States.      Now,  how  can  the  truth  be 
known  when  there  are  so  many  conflicring  statements 
regarding  it?     Would  it  not  be  a  capital  idea  for  the 
American  Medical  Association  to  appoint  a  commission 
of  unprejudiced  and   uninterested  men,   to   come  and 
spend  some  months  in  Florida  and  make  an  official  re- 
port of  what  facts  could  be  gathered,  both  as  to  Florida 
in  general  and  as  to  particular  localities  ?     No  doubt 
physicians  of  note  could  be  found  who,  on  account  of 
catarrhs,  bronchitis,  etc,  would  be  glad  to  spend  a  few 
months  in  our  genial  clime.     Will  not  Dr.  John  T.  Met- 
calf,  of  New  York,  favor  the  readers  of  The  Medical 
Record  with  his  views  of  Florida  as  a  health  resort  ?    I 
am  told  that  he  spent  several  months  in  and  around 
Gainesville  some  years  ago." 

The  Removal  of  Bodies  from  one  Burving-ground 
TO  Another. — The  question  of  the  right  to  remove  the 
body  of  a  person  from  one  resting-place  to  another  is 
frequently  up  before  the  courts  for  determination  ;  but 
an  unusually  curious  instance  occurred  recently  in  Brook- 
lyn. A  gentleman  named  Gardiner  H.  Wolcott,  residing 
in  Astoria,  died  in  t88i,  and  was  buried  in  Greenwood 
Cemetery.  He  was  supposed  to  be  intestate,  and  his 
property,  amounting  to  about  forty  thousand  dollars,  was 
divided  up  between  his  heirs.  Not  long  since  a  will  was 
discovered  directing  that  his  body  should  be  buried  in 
Greendale  Cemetery,  Meadville,  Pa.  An  application 
was  then  made  to  the  Surrogate  for  a  sufficient  allowance 
to  carry  out  this  wish,  which  was  opposed  by  the  relatives 
of  the  deceased  man,  who  would  be  obliged  to  contribute 
their  respective  shares  to  meet  the  expense.  The  deci- 
sion of  the  Surrogate  was  to  the  effect  that,  as  the  estate 
was  divided  up,  and  the  relatives  opposed  the  reinter- 
ment, the  body  must  remain  where  it  was. 


The   Medical   Record 

A    Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  II 


New  York,  September  13,  1884 


Whole  No.  723 


©riflitml  Ji^rtijcIjeB. 


SUCCESSFUL   OESOPHAGOTOMY    FOR    THE 
REMOVAL  OF  FOREIGN  BODIES. 

By  LKROY  McLean,  M.D., 

SUKGBON  TO  TROY  HOSPITAL,  TROV,  K".  Y. 

Ik  the  number  of  this  journal  for  April  29,  1876,  I  re- 
corded two  cases  of  oesophagotomy.  To  those  I  have 
now  to  add  three  others,  malung  in  all  five  oesophagoto- 
mies  done  for  the  removal  of  foreign  bodies.  A  summary 
of  the  two  cases  referred  to  will,  I  think,  be  of  interest 
in  connection  with  those  I  am  about  to  report 
Case  I.  Tooih-flaie  swallowed  during  sleep  ;  cesopha- 

l^my;  recovery. — Mr.  C ,  of  West  Troy,  N.  Y., 

daring  sleep  swallowed  a  gold  tooth-plate  with  one  cen- 
tra] incisor  attached.  The  plate,  which  was  crescent- 
shaped,  measured  from  point  to  point  one  and  a  half 
inch,  and  one-half  inch  from  outer  to  inner  edge.  On 
die  outer  edge  were  eight 
sharp  and  irregular  projec- 
tions which  fitted  between 
the  teeth  and  held  the 
plate  in  position  (see  Fig. 

I  saw  him  tl^ee  days  af- 
ter die  accident,  after  many 
attempts  to  dislodge  had 
been  made,  and  after  the 


Fig.  zJ 


conclusion  was  reached 
that  the  foreign  body  had 
been  pushed  into  the  stomach.  He  was  sufifering  intense 
pain ;  neck  swollen  and  inflamed  ;  all  nourishment  regur- 
gitated ;  voice  faint  and  husky.  The  foreign  body  could 
be  easily  grasped  with  oesophageal  forceps,  but  the  appli- 
cation of  much  force  to  dislodge  it  was  deemed  impractica- 
ble owing  to  the  many  points  of  resistance  which  the  sharp 
projections  on  it  offered.  The  operation  was  performed 
the  following  day.  Incision  on  the  left  side  three  inches 
long,  extending  from  top  of  thyroid  cartilage  downward, 
midway  between  it  and  the  sterno-cleido-mastoid.  Upon 
reaching  the  oesophagus  a  large-sized  lithotomy  stafif  was 
introduced  through  the  mouth  and  the  oesophagus  pushed 
forward,  into  which  a  longitudinal  incision  was  made,  the 
hnger  introduced,  and  the  foreign  body  with  much  diffi- 
culty removed  fi-om  its  resting-place  just  below  the 
cricoid  cartilage. 

The  wound  in  oesophagus  was  not  closed.  For  the 
first  day  eneniata  of  beef-tea  were  given,  and  bits  of  ice 
allowed  to  dissolve  in  the  mouth.  After  twenty-four 
hours  was  allowed  to  drink  milk,  one-third  escaping  from 
wound.  Third  day,  could  swallow  fluids  readily,  very 
little  escaping.  Fourth  day,  ate  an  oyster,  swallowing  it 
without  experiencing  pain.  Fifth  day,  sat  up  dressed ; 
could  readUy  swallow  soft  solids  ;  no  discharge  of  fluids 
by  wound.  Sixth  day,  was  out  of  doors.  Twentieth  day, 
resumed  business;  wound  entirely  healed.* 

Case  II.  Tooth-plate  impacted  in  cardiac  portion 
9f  ouophagus  eleven  months^  causing  stricture ;  (esopha- 

ioiomy ;  recovery, — Mr.  P ,  of  Gansevoort,  N.  Y., 

while  at  dinner  dislodged  four  upper  false  teeth  attached 
to  a  silver  plate  by  striking  them  with  his  fork.     They 

I  He  is,  at  this  daMC(Jaly,  1884)  enjoying  good  health. 


Fig.  3. 


were  involuntarily  swallowed,  passing  into  the  oesopha- 
gus. The  plate  was  one  and  a  half  inch  broad,  by 
about  one  inch  in  depth  from 
front  to  rear  (see  Fig.  2). 

His  physician  was  summoned, 
but  did  not  arrive  until  evening, 
when  an  attempt  was  made  to 
reach  the  teeth.  Instruments 
were  passed  down  over  ten 
inches,  but  failed  to  give  any  in- 
dications of  touching  them,  leav- 
ing the  inference  that  they  might  have  passed  into  the 
stomach.  This  was  strengthened  by  a  sharp  and  severe 
pain  which  he  felt  in  the  region  of  the  stomach.  Within 
a  fortnight  most  of  the  pain  and  soreness  had  passed  away, 
and  he  was  enabled  to  swallow  liquids  without  difficulty 
and  most  kinds  of  food  with  var3ang  success.  He  fre- 
quently passed  weeks  without  any  marked  inconvenience; 
at  times,  however,  there  would  be  unusual  distress  in  the 
chest,  or  a  return  of  the  difficulty  of  swallowing.  He 
first  consulted  me  ^  months  after  the  accident,  when  I 
found  that  the  teeth  were  still  in  the  oesophagus,  eleven 
and  a  half  inches  from  front  of  upper  jaw  while  the 
head  was  thrown  back.  An  operation  was  advised :  thb 
he  wished  to  delay,  as  he  was  not  sufifering  essentially. 
For  five  months  nothing  was  done,  when,  as  he  was 
having  great  difficulty  in  swallowing,  I  was  consulted. 
Ab  operation  was  again  advised,  to  which  he  assented. 
7%is  was  eleven  months  and  seven  days  from  date  of  cu- 
cident.  The  incision  was  made  on  the  left  side  of  the 
neck,  commencing  opposite  the  thyroid  cartilage  and 
reaching  to  the  sternum.  The  oesophagus  was  reached 
without  difficulty,  and  an  opening  large  enough  to  admit 
the  finger  made  in  it  as  near  the  sternum  as  possible. 
Passing  a  finger  through  the  incision  and  downward  a 
constriction  was  felt,  below  which  lay  the  foreign  body 
quite  out  of  reach.  A  polypus  forceps  was  then  directed 
by  the  finger  down  upon  the  plate,  which  was  soon 
brought  up,  without  the  teeth,  however,  they  having  be- 
come detached  in  the  eflFort  at  removal.  The  teeth  were 
voided  by  the  rectum  some  days  after.  Wound  not  closed. 
He  began  to  take  liquid  nourishment  by  mouth  on  the 
third  (3&y.  On  the  thirteenth  day  walked  out  of  doors. 
Owing  to  a  troublesome  cough  the  wound  did  not  close 
until  the  sixth  week,  at  which  time  he  resumed  his  busi- 
ness. He  rapidly  regained  his  health,  which  at  this 
writing  is  still  excellent. 

Case  III.  An  infant  swallows  a  penny  ;  cesophagot* 
omy :  recovery, — E.  F ,  aged  sixteen  months,  re- 
siding in  Lansingburg,  N.  Y.,  while  playing  with  an  ordi- 
ixary  nickel  cent,  put  it  into  his  mouth  and  swallowed  it. 
The  family  physician.  Dr.  Capron,  who  was  immediately 
summoned,  after  carefully  examining  the  child  concluded 
that  the  penny  had  passed  into  the  stomach,  and  directed 
that  the  stools  be  watched.  On  the  27th  he  was  again 
called  and  found  that  the  child  was  regurgitating  most  of 
the  food  taken.  A  probang,  with  sponge  attached  at 
end,  was  passed  to  the  stomach.  This  for  a  time  seemed 
to  afiford  relief.  On  the  28th  and  29th  an  olive-pointed 
probang  was  passed  with  no  eflfect,  the  food  being  per- 
sistently regurgitated.  I  was  called  to  the  case  on  the 
30th.  The  patient  was  then  refusing  absolutely  to  take 
nourishment,  and  was  beginning  to  sufifer  from  want  of 
food.  The  olive-pointed  and  sponge  probang  was  again 
introduced,  but  as  they  gave  no  indication  of  contact 
with  the  foreign  body,  a  metallic  catheter  guide  (Otis*) 


282 


THE   MEDICAL  RECORD. 


[September  13,  i9Z^ 


Fig.  3. 


was  passed.  A  distinct  click  was  heard  as  it  was  moved 
up  and  down  within  the  oesophagus.  The  sponge  pro- 
bang  was  again  tried  but  the  penny  could  not  be  dis- 
lodged, the  instrument  passing  beyond  it  at  each  intro- 
duction. The  point  of  impaction  seemed  to  be  at  a 
point  on  a  level  with  the  clavicle.  On  the  31st  another 
effort  was  made  with  a  like  result  As  the  child  was  be- 
coming rapidly  reduced  from  inanition,  an  immediate 
operation  was  decided  upon. 

.  With  the  assistance  of  Dr.  Schuyler,  Dr.  Capron,  and 
the  Drs.  Bucklin,  of  Lansingburg,  the  operation  was  done 
at  1 1  A.M.  The  incision  was  made  upon  the  left  side. 
The  dissection  was  exceedingly  slow  and  tedious,  owing 
to  the  minute  anatomy  of  the  patient.  The  oesophagus 
was  nnally  reached  without  tying  a  vessel.  A  small 
laryngeal  brush-holder,  to  which  was 
attached  an  ivory  tip,  was  substituted 
for  the  lithotomy  staff  in  pushing  the 
oesophagus  forward  ;  with  this  excep- 
tion, the  various  steps  of  the  operation 
did  not  differ  from  those  in  previous 
cases.  The  penny  (see  Fig.  3)  was 
found  where  it  had  been  located  pre- 
vious to  the  operation,  i.if.,  on  a  level 
with  the  clavicle.  It  was  removed  with  a  Gross  polypus 
forceps.  The  wound  was  not  closed.  The  recovery  was 
rapid  and  complete.     No  impairment  of  voice. 

Case  IV.  A  tooth-plate  swallowed  while  asleep ; 
removed  by  oesophagotomy  twelve  years  after ;   death, 

— J.  F ,  aged  thirty-six,  of  Albany,  in  August,  1869, 

swallowed  while  asleep  a  tooth-plate  with  two  central 
incisors  attached.  The  plate, 
which  was  of  rubber,  measured 
one  and  a  half  inch  in  width, 
and  one  and  one-fourth  from 
front  to  rear  ^see  Fig.  4). 

Medical  aid  was  sought  at 
once,  and  efforts  made  at  re- 
moval. It  was  finally  concluded 
that  the  plate  had  passed  into 
the  stomach,  as  he  felt  greatly 
relieved  after  the  introduction 
of  the  instruments.  He  was  then 
removed  to  the  city  hospital,  and  kept  under  observation 
for  some  days ;  but  as  nothing  resulted,  and  as  he  felt 
perfectly  well,  he  left  the  institution  and  the  city  to  make 
his  home  in  Omaha.  For  ten  years  he  suffered  no  pain, 
and  but  little  inconvenience,  and  then  only  when  large 
pieces  of  food  were  swallowed.  During  the  next  two 
years,  however,  the  difficulty  in  deglutition  greatly  in- 
creased, until  it  was  almost  impossible  to  swallow  even 
fluids.  Believing  that  he  could  not  long  survive  this  con- 
dition, he  concluded  to  seek  medical  advice.  Getting 
no  encouragement  in  the  West  from  physicians  whom 
he  consulted,  he  came  to  Troy  seeking  the  counsel  of 
his  relatives. 

I  saw  him  then  for  the  first  time.  This  was  twelve 
years  and  two  months  from  time  of  accident.  He  was 
greatly  emaciated.  Most  of  the  liquid  nourishment  (the 
only  form  in  which  it  could  be  swallowed)  taken  was  im- 
mediately regurgitated.  His  face  bore  an  anxious  ex- 
pression ;  was  very  solicitous  as  to  the  immediate  future, 
and  begged  that  something  might  be  done  for  his  relief. 

Upon  passing  an  olive-pointed  probang,  an  impassable 
obstruction  was  found  eleven  inches  from  incisor  teeth. 
As  the  instrument  gave  no  evidence  of  contact  by  sound, 
it  was  inferred  that  the  foreign  body  had  become  en- 
cysted, and  all  efforts  at  removal  in  that  direction  were 
abandoned.  The  operation  was  done  at  the  Troy  Hos- 
pital, November  2,  188 1,  with  the  assistance  of  Drs. 
Schuyler  and  Nichols,  and  other  members  of  the  hos- 
pital staff  Owing  to  his  extreme  emaciation  the  oesoph- 
agus was  easily  and  quickly  reached,  and  opened  at 
the  lowest  possible  point.  By  introducing  the  finger  it 
was  possible  to  reach  the  obstruction.  It  was  then 
found  that,  with  the  exception  of  a  tip  of  one  of  the 


Fig.  4- 


wings,  the  plate  was  completely  encysted.  By  the  aid 
of  the  finger  and  an  oesophageal  forceps,  the  plate,  after 
prolonged  effort,  was  lifted  from  its  resting-place. 
A  single  suture  was  introduced  at  upper  end  of  ex- 
ternal  wound,  otherwise  it  was  left  open  as  in  previous 
cases.  A  nutritive  enema  with  brandy  was  administered 
and  the  patient  put  to  bed.  Then  for  the  first  time  a 
peculiar  wheezy  and  labored  respiration,  and  slight  em- 
physema  in  the  wound,  were  noticed.  He  did  not  rally 
well ;  though  he  was  enabled  to  swallow  considerable 
milk  and  brandy  (by  holding  the  edges  of  the  wound  to- 
gether)  and  retain  the  enemata,  he  gradually  sank.  The 
emphysema  increased,  the  respiration  became  more  em- 
barrassed, and  the  exhaustion  more  pronounced,  until 
the  time  of  his  death,  which  occurred  forty-eight  hours 
after  operation. 

The  autopsy  was  made  twelve  hours  after  death.  The 
wound  was  found  to  be  healthy.  There  was  no  evidence 
of  inflammation  of  parts  at  the  point  of  impaction  of  the 
plate.  Search  was  made  for  the  cause  of  the  emphysema 
which  appeared  immediately  after  the  operation.  It  was 
thought  that  during  the  removal  of  the  plate  firom  its 
surroundings  a  slight  perforation  of  the  trachea  had 
occurred,  but  the  most  careful  search  revealed  nothing, 
however,  to  confirm  this  belief. 

The  conclusion  finally  reached  was,  that  during  a 
violent  fit  of  coughing  at  the  time  of  the  administration 
of  the  anaesthetic  the  expiratory  effort  ruptured  some  of 
the  air-vesicles,  the  air  first  escaping  into  the  cellular 
tissue  between  the  lobules  of  the  lung,  then  into  the 
mediastinum,  and  from  thence  to  the  root  of  the  necL 
The  presence  of  dyspnoea  after  the  operation  would 
seem  to  strengthen  this  belief.  He  undoubtedly  died  of 
exhaustion. 

Case  V.   Tooth^late  swallowed  while  asleep  ;  eesopK 

agotomy  ;     recovery. — Mr.     K ,    aged    thirty-eight, 

residing  in  East  Greenbush,  N.  Y.,  on  April  9,  1884, 
retired  at  12.30  a.m.  About  3  a.m.  he  was  suddenly 
awakened  by  a  sharp  burning  pain  in  his  throat 
Springing  from  his  bed  he  hastily  swallowed  a  glass  of 
water  and  felt  relieved.  Retiring  again,  the  pain  soon 
retimied  with  increased  violence. 

He  then  for  the  first  time  discovered  that  his  tooth- 
plate  was  missing.  After  a  fruitless  search  in  the  bed 
and  upon  the  floor  he  concluded  he  had  swallowed  it, 
and  immediately  sent  for  a  physician,  who,  after  intro- 
ducing an  oesophageal  probang,  assured  Mr.  K that  he 

had  pushed  the  foreign  body  into 
the  stomach.  The  plate,  which  was 
of  rubber,  had  four  incisor  teeth 
attached,  and  measured  one  and  a 
half  inch  from  firont  to  rear,  and 
one  and  a  fourth  inch  in  width. 

I  was  consulted  on  the  third 
day.  He  complained  of  intense 
pain  in  the  region  of  the  stomach, 
which  was  increased  at  each  act  of 
swallowing.  The  expression  of 
countenance  was  anxious,  his 
general  appearance  that  of  a  per- 
son after  a  severe  illness. 

Passing  an  olive-pointed  pro- 
bang,  an  obstruction  was  found  at  cardiac  end  of  oesopha- 
gus, thirteen  and  a  half  inches  from  incisor  teeth. 
Bringing  the  instrument  in  contact  with  the  foreign  body, 
a  metallic  click  could  be  distinctly  heard. 

The  exertion  of  ordinary  force  failed  to  remove  the 
obstruction.  Appreciating  the  liability  of  injury  to  the 
parts,  prolonged  and  greater  effort  was  deemed  unwise, 
and  an  operation — cesophagotomy — ^was  suggested  to  the 
patient.  To  this  he  demurred,  preferring  to  wait  for  at 
least  a  few  days.  Advising  him  of  the  danger  of  delay, 
I  left  him.  On  the  fifth  day  he  entered  the  Troy  Hos- 
pital. Since  last  seen  says  he  has  suffered  intensely ;  is 
able  to  swallow  but  small  quantities  of  liquid  nourish- 
ment, which  act  is  attended  with  increased  pain. 


Fig.  5. 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


283 


£ffi)rts  to  dislodge  were  again  made  without  success. 
He  was  now  ready  and  anxious  for  an  operation,  and  the 
following  day  was  therefore  appointed.  The  operation 
yns  done  at  11  A.M.,  with  the  assistance  of  Dr.  Nichols 
2Dd  members  of  the  hospital  staff. 

Reaching  the  oesophagus  in  the  usual  manner,  from  the 
left  side,  it  was  opened  vertically  upon  a  lithotomy  staE 
The  foreign  body  was  found  to  be  quite  out  of  reach  of 
the  finger.  It  could  be  readily  felt,  however,  by  intro- 
dacing  a  long  forceps,  but  in  this  manner  it  could  not  be 
grasped  securely  enough  to  admit  of  extraction. 

Unsuccessful  attempts  were  then  made  to  pass  beyond 
and  over  the  plate  loops  of  silk.  Finally,  a  sponge  at- 
tached to  the  probang  was  carefully  passed  beyond  the 
obstruction,  and  upon  removing  it  the  sponge  became 
engaged,  and  the  foreign  body  was  brought  to  the  open- 
ing and  removed  by  the  fingers  of  the  operator.  The 
wound  was  not  closed. 

It  should  be  stated,  that  in  carrying  the  dissection  as 
Dear  the  sternum  as  possible,  the  anterior  jugular  vein  was 
divided  It  was  soon  secured,  with  but  little  loss  of 
blood,  and  without  apparent  entrance  of  air.  The  pa^ 
tient  was  put  to  bed,  and  a  nutritious  and  stimulating 
enema  administered  soon  after.  He  rallied  well.  For 
the  first  few  hours  was  allowed  to  dissolve  bits  of  ice  in 
the  mouth.  .  Nine  hours  after  the  operation  he  drank,  by 
holding  the  edges  of  the  wound  together,  a  goblet  of  milk. 
The  temperature  then — ^the  highest  point  reached  during 
convalescence — was  iooj-°.  The  recovery  from  this 
tine  was  very  rapid.  On  the  ninth  day  he  sat  up  and 
ate  six  oysters,  a  slice  of  bread,  and  one  egg.  The 
wound  closed  on  the  eleventh  day.  Three  weeks  from 
the  d^y  of  operation,  he  left  the  hospital,  cured.  The 
following  yrevk,  he  resumed  his  usual  avocation — that  of 
a  toner. 

In  reviewing  the  various  steps  of  an  operation  to  reach 
the  oesophagus  by  external  incision,  Professor  Cheever* 
so  well  expresses  wb^t  I  want  to  say  that  I  cannot  do 
better  than  quote  him  verbatim.  A  more  definite  or 
concise  statement  has  not^  to  my  knowledge,  been  pub- 
lished. He  says :  *'  It  appears,  first  of  all,  diat  this  in- 
cision  cannot  well  exceed  &ree  to  three  and  a  half 
inches  in  length.  This  is  about  the  distance,  in  average 
oecks,  from  the  top  of  the  thyroid  cartilage  to  the  ster- 
num. If  ^e  cut  above  the  thyroid  cartilage  we  en- 
danger the  hypoglossal  nerve  and  lingual  artery,  in  a 
deep  dissection;  and,  more  important,  the  superior 
taryngeal  nerve.  The  latter  crosses  the  space  between 
die  hyoid  bone  and  top  of  the  thyroid  cartilage  to  enter 
die  larynx,  and  its  section  would  destroy  the  sensibility 
of  one  vocal  cord,  and  one-half  of  the  glottis.  Through 
a  comparatively  short  incision,  therefore,  we  are  obliged 
to  make  a  very  deep  dissection  down  to  the  prevertebral 
muscles,  and  to  draw  various  important  structiures  out 
of  harm's  way  as  we  proceed.  First,  the  carotid  sheath, 
containing  the  artery,  vein,  and  pneumogastric  nerve, 
which  approximate  closer  and  closer  toward  the  cesopli- 
agus,  as  we  descend  the  neck.  Above  and  below  are 
the  superior  and  inferior  thyroid  arteries ;  on  the  inside 
the  thyroid  gland;  below  the  finger,  the  S)rmpathetic 
.nerve.  And,  finally,  running  between  the  oesophagus 
and  trachea,  to  the  back  of  the  larynx,  the  inferior,  or 
recurrent  laryngeal  nerve^  the  motor  nerve  of  the 
laiynx,  whose  section  would  paralyze  one-half  of  the 
glottis;  and  the  partial  division  of  some  filaments  of 
which,  in  one  case  of  oesophagotomy,  led  to  a  per- 
manent alteration  of  the  voice.  This  nerve,  lying  upon 
the  front  of  the  oesophagus  principally,  is  to  be  avoided 
by  opening  the  ^llet  toward  its  posterior  part.  The 
oesophagus  is  easier  found  also  on  the  left  side  of  the 
neck,  as  it  naturally  inclines  to  that  side.  And  the  rule 
has  been  laid  down  that  oesophagotomy  should  be  done 
on  Ae  left  side  as  the  place  of  election,  unless  we  are 
sure  of  cutting  down  on  the  foreign  body  on  the  right 

>  Two  Cases  of  CEsophagotomy,  etc.    Boiton.    x868. 


side.  The  deeper  dissections  being  carried  on  chiefly 
with  the  director,  it  is  possible  to  reach  the  oesophagus 
not  only  without  injuring  any  nerves^  except  the  un* 
important  superficial  branches  of  the  anterior  cervical 
plexus,  but  also  without  tying  a  vessel.  There  is,  I 
believe,  but  little  danger  of  wounding  the  recurrent 
laryngeal  nerve  if,  before  opening  the  guUet,  a  lithotomy 
staff,  or  some  sucJi  curved  instrument  be  introduced  by 
the  mouth,  and  its  walls  pushed  well  forward.  This 
facilitates  the  operation  by  bringing  the  parts  well  into 
view." 

The  permanent  alteration  of  voice  in  Case  I.  was  not 
due  to  the  operation,  for  at  the  time  of  my  first  visit,  the 
fourth  day,  I  was  informed  that  he  had  been  unable  to 
speak  above  a  whisper  since  the  day  after  the  accident. 
The  injury  was  probably  done  while  making  fiiiitless  at- 
tempts to  dislodge. 

There  is  a  diversity  of  opinion  as  to  the  treatment  of 
the  patient  after  the  operation. 

Boyer,  it  is  said,  was  the  first  to  advise  absolute  diet 
for  a  week  and  the  non-employment  of  elastic  tubes  to 
feed  the  patient  through. 

Syme  [advocated  the  early  use  of  the  tubes,  and  the 
weight  of  authority  seems  to  lean  in  that  direction,  yet  it 
is  doubtfiil  if  many  have  spoken  from  actual  experi- 
ence. Cheever  believes  that  the  irritation  of  passing 
tubes,  however  gently,  is  considerable ;  and  the  risk  of 
touching  granulations,  thus  lessening'chances  of  early  re- 
pair, is  very  great.  I  believe  this  to  be  true,  for  a  tube 
cannot  be  passed  with  any  degree  of  accuracy  when  once 
it  is  {within  the  oesophagus,  making  contact  with  the 
wound  almost  certain.  Experience  has  taught  me  to 
believe  that  the  use  of  tubes  is  not  essential,  and  that 
there  is  nothing  to  contraindicate  the  administration  of 
liquid  nourishment  in  small  quantities,  by  the  mouth, 
within  a  few  hours  after  operation.  The  danger  of  infil- 
tration among  the  long  muscles,  leading  to  suppuration, 
aft  suggested  by  Cheever,  is,  I  think,  ml. 

It  has  occurred  to  me  that  the  frequent  passage  of  the 
escaping  fluid  through  the  oesophageal  wound  during  the 
process  of  repair,  has  a  tendency  to  evert  its  ed^es.  If 
this  be  so,  and  it  seems  reasonable,  such  a  condition  of 
things  is  to  be  encouraged. 


ON  THE  PREPARATION  AND  USE  OF  OXY- 
GEN  AND  ITS  CONGENERS  AS  REMEDIAL 
AGENTS. 

By  SAMUEL  S.  WALLIAN,  A.M-,  M.D., 

BLOOMINGDAUC,  N.  Y. 

Following  the  appearance  of  my  paper  on  oxygen,  etc, 
in  The  Medical  Record  of  October  27  and  November 
TO,  1883,  I  received  from  every  direction  a  flood  of 
professional  inquiry.  To  a  few  applicants  I  made  brief 
response  by  letter. 

As  the  tenor  of  all  was  the  same,  viz.,  an  eager  anxiety 
for  definite  practical  details  in  the  matter  of  preparing 
and  exhibiting  the  agents  in  question,  and  since  I  found 
it  utterly  impracticable  to  make  satisfactory  reponse  by 
letter  to  even  a  few  of  the  many  inquirers,  I  will,  at  the 
urgent  request  of  numerous  correspondents,  endeavor  in 
this  paper  to  summarize  such  practical  details  as  may 
assist  those  practitioners  who  have  not  as  yet  given  much 
attention  to  the  subject. 

Apparatus. — ^Those  practitioners  who  live  in  or  near 
large  cities  may  find  it  more  convenient  to  purchase  both 
oxygen  and  nitrogen  monoxide  compressed  in  iron  flasks ; 
suitable  contrivances  being  provided  for  their  proper  ex- 
pansion, dilution,  and  dispensation.  A  constant  adver- 
tiser in  The  Record  offers  to  supply  "pure  oxygen" 
and  suitable  inhaling  apparatus  for  medical  purposes, 
and  the  dental  depots  supply  the  nitrogen  monoxide 
compressed  so  as  to  be  readily  portable.  If  one  can 
trust  to  the  manufacturer  for  the  absolute  purity  of  his 


284 


THE  ICEDICAL  RECORD. 


[September  13,  1884, 


product,  this  method  of  procuring  the  gases  saves  a  woi'ld 
of  trouble  and  vexation ;  but  as  I  have  had  no  personal 
experience  with  them  I  can  neither  commend  nor  oon* 
demn.  The  only  feasible  method  for  those  who  live  at 
a  distance  from  these  sources  of  supply,  and  the  least 
expensive  for  all,  is  by  procuring  the  necessary  apparatus 
and  manufacturing  at  one's  own  <^ce. 

For  storage  I  use  a  meter-holder  made  of  sheet  sine 
or  tinned  copper.  A  convenient  size  is  thirty  inches  in 
diameter  by  about  thirty-two  or  thirty-four  inches  in 
height — the  width  of  ordinary  sheet  zinc  will  do.  This 
will  admit  a  bell  or  receiver,  corresponding  to  the  gas- 
ometer of  ordinary  city  gas  works,  with  a  capacity  of  up* 
ward^  of  a  hundred  gallons.  In  a  large  practice,  or  in 
hospitals,  much  larger  receptacles  may  be  used,  but  it  is 
better  to  have  tevefal  of  moderate  size  rather  than  one 
large  one,  thus  enabling  the  physician  to  have  various 
admixtures  and  dilutions  on  hand  at  the  same  time. 

The  tank  or  holder,  answering  to  the  well  of  gas  works, 
is  to  be  filled  with  pure  water,  and  should  have  a  tap  with 
rubber  cork,  or  a  faucet,  near  the  bottom  for  convenience 
in  drawing  off  the  water  when  necessary  to  renew  it 
To  facilitate  this  operation  it  is  well  to  place  the  tank 
on  a  frame  or  platform  eight  or  ten  inches  high,  and  it 
should  also  have  a  false  bottom  of  wood  beneath  the 
metal  one  to  strengthen  it.  A  broad  metal  hoop  at  top, 
bottom,  and  middle  is  necessary  to  keep  it  firm  in  shape. 
The  inverted  bell  or  gasometer  should  have  a  gas-cock 
soldered  into  the  top,  through  which  to  admit  thie  gas, 
with  ears  at  opposite  sides  by  which  to  [suspend  or 
balance  it.  For  the  latter  purpose  cords,  weights,  pul- 
leys, and  a  light  framework  will  suggest  themselves. 
At)  approximate  scale,  estimated  in  either  cubic-  inches 
or  centimetres,  as  preferred,  can  be  readily  arranged  6n 
this  framework,  or  on  the  side  of  the  bell  itself  for  the 
purpose  of  measuring  the  volume  of  the  gases  as  manu- 
.fJBtctured,  comminglbd,  or  respired. 

For  any  conMderable  practice,  not  less  than  thale 
rte6rvoirs  will  be  found  necessary,  as  well  as  convenftam.' 
lb  one  should  be  kept,  at  all  times,  a  supply  of  pute 
oxygen ;  in  a  second,  pure  nitrogen  monoxide  ;  the  third 
may  be  used  for  any  standard  admixture  or  dilution  'Of 
the  two,  or  either  of  them,  as  desired. 

As  an  external  finish  a  coat  or  two  of  paint,  or  grain- 
ing and  varnishing  in  imitation  ^f  wood,  adds  to  the 
appearance  and  durability  of  the  ni'^tal  reservoirs. 

Both  the  gases  usrd  must  be  well  washed  and  purified 
as  they  are  evolved.  I  use  a  series  of  four  or  five  wash* 
bottles  for  this  purpose,  connected  by  means  of  glass 
and  rubber  tubing.'  Th^se  bottles  may  be  procured 
ready  fitted  from  manufacturers  of  glassware  through  your 
local  druggist,  or  you  may  fit  them  yourself  at  less  ex- 
pense. 

For  this  purpose  procure  half-gallon  or  gallon  specie 
jars,  with  rubber  corks  to  fit,  each  cork  to  be  perfor- 
ated mth  two  holes,  say  three-eighths  of  an  inch  in  diam- 
eter, for  the  insertion  of  the  glass  tubing.  Common  corks 
can  be  made  to  answer  by  carefully  cementing  them  with 
fine  plaster-of-Paris  after  the  fittings  are  all  in  position. 

Select  the  soft  or  soda  glass  tubing  of  about  three- 
eighths  of  an  inch  calibre,  and  not  too  heavy.  This  can  be 
readily  broken  into  any  desired  length  by  first  nicking  it 
on  one  side  with  a  sharp  file  and  then  bend  at  right 
angles,  after  heating  in  the  flame  of  a  gas-jet  or  of  an 
ordinary  spirit-lamp.  Hard  varieties  of  glass  may  be  bent 
by  thrusting  the  ends  into  a  bed  of  glowing  coals  for  a  few 
.moments,  should  the  flame  heat  prove  insufficient. 

A  copper  retort  with  suitable  connections  for    the 

.  preparsttioa  of  oxygen  can  be  procured  from  any  dealer 

ia  chemical  apparatus.     The  size  selected  may  vary  from 

one  to  four  pints  capacity  as  needed.     Common  glass 

retorts  may  be  used  in  lieu  of  copper  for  generating  oxy- 

.<«*  The  following  u  a  hit  assortment  of  tubing  for  fittingt :  Four  pieces  X^nch 
glass  tubinjs,  thirtv  inches  long ;  four  pieces  Jji-inch  glass  tubing,  thirty  inches 
lon^ ;  one  piece  ^-inch  rubber  tubing,  eight  feet  long  :  one  piece  X'lacn  rubber 
tubing,  six  feet  l^ng. 


gen,  but  the  bills  for  fractured  glass  and  the  results  of 
occasional  explosions  render  them  both  vexatious  and  ex- 
pensive. 

For  preparing  nitrogen  monoxide  the  same  appara- 
tus is  complete,  except  that  a  glass  or  porcelain  fiask 
must  be  substituted  for  the  copper  retort.  A  half-galloa 
Florence  flask  fitted  with  perforated  rubber  cork  and 
long  bent  glass  tube  of  good  calibre,  to  connect  with  the 
first  (or  empty)  wash^bottle,  noakes  a  very  satisfactory 
airangement  Platinum  or  gold  flasks  are  perfect,  since 
they  thoroughly  resist  the  action  of  the  chemical  used, 
but  are,  of  course,  expensive.  I  prefer  to  use  glass  for 
various  reasons,  even  if  there  is,  as  a  result,  a  fractured 
flask  and  a  be^>attered  floor  or  table  occasionally.  In 
glass  the  material  can  be  more  closely  watched  during 
the  process,  and  the  danger  of  applying  excessive  heat 
more  surely  avoided*  The  first  or  empty  wash-bottle 
acts  as  a  safety  valve,  preventing  r.eflow  of  water  into  the 
flask  in  case  of  sudden  withdrawal  of  heat  or  of  an  acci- 
dent. 

Chemicals. — The  mat.erials  used  for  preparing  pure 
■oxygen  by  the  process  now  under  consideration  are 
potassium  chlorate  (KCIO,)  and  manganese  dioxide 
(peroxide)  (MnOj. 

The  latter,  it  is  hardly  necessary  to  stale,  is  not  chemi- 
cally changed  during  the  process,  but  acts,  merely  by  its 
presence.  Both  chemicals  should  be  as  pure  as  can  be 
procured,  thoroughly  dried  and  finely  pulverized  previous 
to  usin^.  It  is  even  better  to  evaporate  the  water  of 
crystallization  in  case  of  the  chlorate,  and  it  must  be 
very  thoroughly  rubbed  up  wiifch  the  maifganese  in  a  dry 
mortar,  the  most  favorable  proportions  being  four  or  five 
of  the.potaasium  to  one  of  manganese.  The  exact  pro- 
portion is  not  essential ,  and  need  not  be  uniform,  oue 
part  of  the  former  in  eight  or  ten  of  the  latter  working 
very  well.  Since  it  ia  so.diflicult  to  make  it  fine  enough 
by  hand,  and  requires  so  much  labor  vrithal,  I  prefer  to 
buy  the  pulveri^  chlorate  of  potassium  of  the  brand 
known  as  "chemically  pure." 

For  nitrogen  monoxide,  1  procure  simply  pure  fiised 
crystallized:  or  granulated  aounonium  nitrate  (NH^NO,). 
It  will  not  matter  which  of  the  three  varieties  is  selected, 
so  that  the. salt* be  pure  and  clean. 

Heat  decomposes  this  salt  into  nitrogen  monoxide 
(N^O)  and  water  (H,0).  If  the  heat  be  too  ^eat  or  too 
rapidly  applied^  fumes  of  nitrous  or  hypomtrous  acid 
(HNO)  will  be  driven  over,  to  be  absorbed  by  the  water 
in  the  wash*bottles. 

Chemical  manipulatums. — To  prepare  pure  oxygen  fill 
the  copper  retort  half  full  of  the  prepared  potassium  and 
manganese  mixture,  connect  securely  with  the  series  of 
wash-bottles,  the  last  one  of  the  latter  to  be  connected 
by  a  loil^  rubber  tube  to  the  gas-cock  in  the  bell  or 
meter. .  Apply  heat  by  means  of  the  sand-bath,  a  jet  of 
iiouse  gas,  a  spirit-lamp  with  several  small  wicks  or  ooe 
large  one,  or  by  a  small  kerosene  stove.  No  gas  is 
given  ofi*  until  the  whole  mass  has  been  heated  to  a 
rather  high  and  uniform  degree,  at  which  point  the  evo- 
lution is.  sudden  and  rapid,  frequently  trying  the  wash- 
bottles  and  connections  severely.  The  heat  should  be 
promptly  diminished  at  this  juncture,  to  be  increased 
again  as  the  material  begins  to  be  exhausted. 

The  reaction  consists  simply  in  the  disengagement  of 
both  equivalents  of  oxygen  from  the  potassium  chlorate, 
potassium  chloride  (KCL)  resulting.  The  flask  is  to 
be  disconnected  from  the  wash-bottles  promptly  when  gas 
ceases  to  pass  over. 

For  nitrogen  monoxide  fill  a  i'lorence  flask  (those  of 
German  glass  answering  best)  half  full  ofammoDium 
nitrate ;  connect  securely  with  the  dry  wash-bottle  by  a 
long  bent  ^lass  tube  (thirty  inches  is  not  too  long),  and 
it  is  well  to  wire  the  cork  to  the  neck  with  copper  or 
platinum  wire  to  prevent  its  being  forced  out  at  a  critical 
moment. 

Apply  heat  gradually  at  first,  preferably  by  means 
of  a  sand-bath,  or  very  cautiously  by  means  of  the  same 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


385 


lamp  used  in  the  process  for  oxygen.  If  the  sand- 
bath  be  dispensed  with  it  will  be  a  good  precaution  to 
suspend  the  flask  over  the  flame  by  a  wire,  and  keep  it 
in  gentle  motion  in»  order  to  apply  the  heat  more  evenly 
and  preyent  the  liability  to  fracture. 

After  a  few  accidents  each  novice  will  learn  discretion 
and  acquire  the  <<  knack,"  ao  as  to  make  as  little  havoc 
with  firs^le  apparatus  as  is  possible.  With  the  besjt  of 
management  and  the  nicest  adjustment  of  all  the  condi« 
tions  accidents  will  sometimes  happen,  and  some  taint 
of  foreign  elements  will  pass  oiver  into  the  first  two  wash* 
bottles,  which  will  therefore,  more  frequendy  than  the 
others,  need  to  be  emptied  and  refilled  More  care  and 
watchfulness  are  required  in  the  preparation  of  this  gas, 
and  the  process  is  slower  than  that  for  oxygen. 

Suggestions  for  administration  and  for  determining 
when  and  idien  not  indicated,  together  with  approximiate 
dosage  and  condensed  reports  of  a  few  additional  cases 
treated,  will  be  given  in  another  paper. 

The  most  difficult  part  of  my  task  remains,  since  in  no 
other  form  of  therapeutic  effort  is  more  careAil  discrimina- 
tion  necessary,  and  in  none,  are  we  confronted  by  a 
greater  dearth  of  precedent  Ordinarily  the  diagnosis 
fiumishes  the  indication,  and  the  age,  condition,  and 
temperament  of  the  patient  are  accredited  as  safe  guides 
to  the  proper  dosage. 

The  agents  myw  under  consideration  are  potent  for 
good  or  evil  in  a  superlative  sense,  and  cannot  be  so  ex- 
bibited  Nor  have  we  in  our  libraries  half  a  centiury's 
accumulations  of  litemture  on  the  subject,  to  which,  as 
in  ordinary  cases,  we  can  refer  for  aid  in  case  of  a 


One  of  the  first  misccmceptions,  or  misapprehensions^ 
to  be  thoroughly  uprooted-<--fbr  it  is  always  necessary  to 
unlearn  errors  before  we  can  comprehend  facts— is  the 
inlerence  or  impression  that  since  these  agents  are  prin^ 
dpally  used  by  inhsdation  thejr  are,  on'  this  accotot,-  par- 
ticularly adapted,  if  not  practically  limited,  to  the  treat- 
ment  of  pidmonary  complaints.  Nothing  could  be 
farther  fixnn  the  truth,  as  will  appear  (com  the  general 
tenor  of  arguments  used  and  fiscts  presented  throughout 
this  series  of  papers.  Oxygen  may  be  now,  or  may  in 
time  become  our  chief  reliance  in  combatiDg  the  strumous 
and  tubercular,  as  well  as  other  diatiieaes ;  but  it  is  not 
and  wiU  not  be  because  it  is  taken*directly  into  the  lungs, 
tiie  apparent  principal  seat  of  tubercular  mamfestations. 

Its  specific  action  is  by  and  through  its  absorption  into 
the  blood  and  its  direct  and  rapid  distribution  to  every 
tissue  dirou^^ut  the  entire  system.  It  thus  becomes,  as 
nl^ady  set  finrth  with  sufficient  emphasis,  an  important 
source  of  supply  to  the  blood,  am  element  of  repair  and 
nmirHian^  already  prepared  for  direct  and  immediate  as* 
similation,  requiring  neither  gastric  solution  nor  intestinal 
modification  in  order  to  become  an  integral  part  of  the 
vital  organism.  Its  eflRects,  therefore,  must  not  be  com- 
pared with  those  which  follow  a  dose  of ''  naedicine  "  in 
the  ordinary  acceptation  of  that  term.  Hence,  while  cer- 
tain immediate  or  acute  morbid  conditicHis  are  quickly 
removed  by  its  timely  exhibition,  it  cannot  be  ranked  as 
«  drug  to  be  divided  into  definite  doses  and  exhibited 
promiscuously  in  all  acute  and  chronic  diseases  at  stated 
intervals,  as  is  the  case  with  the  ordinary  articles  of  the 
Phannacopoeia. 

If,  therefore^,  I  were  to  be  asked  whether  the  oxygen 
treatment  mil  **  cure  "  this  or  that  particular  malady  or 
disease  by  name,  as  phthisis,  carcinoma,  rheumatism, 
epilepsy,  I  should  promptly  answer,  No,  it  will  "  cure " 
no  disease  whatever.  .  If,  on  the  other  hand,  a  profes* 
^onal  brother  should  inquire,  In  what  diseased  condi- 
tions do  you  consider  it  particularly  indicated  ?  I  sliould 
as  promptly  respond.  In  every  cknmit  morM  eondHipn 
of  which  it  is  possible  to  form  a  conception. 

This  may  seem  an  extravagant  estimate,  but  it  really  is 
not,  since  the  question  is  like  asking  in  what  conditions  of 
die  system  is  it  proper  to  administer  nourishment  ?  It  is 
merely  recognizing  the  view  now  coming  to  the  front  in 


medical  philosophy,  that,  in  the  language  of  Ordroneaux, 
'*  We  are  to  treat  it  [disease]  not  as  a  personal  devil  en- 
tirely, to  be  exorcised  by  philters  and  mummery,  but 
rather  as  the  perversion  of  a  natural  state  struggling  to 
regain  its  equilibrium.'^  * 

Another  stereotyped  error  in  connection  with  the  use 
of  oxygen  as  a  remedy  must  be  eradicated  frpm  the 
average  medical  mind.  It  is  assumed,  on  the  basis  of 
an  ancient  chemical  dogma,  that  this  element  is  pre-emi- 
nently a  destroyer;  that  it  is  the  principal,  or  even  sole 
office  of  the  oxygen  ins(Hred  to  break  down  used  tissues, 
to  eliminate  refuse  material,  to  *'  burn  up  "  waste  pro- 
ducts ;  and  that  more  oxygen  means  simply  and  neces- 
sarily more  extensive  waste,  more  rapid  destruction — a 
hotter  fire  !  This  is  another  of  the  superannuated  myths 
of  science.  It  is  true  that  living  is  synonymous  with 
wasting,  disintegration — burnings  if  you  insist  on  the 
misnomer — but  to  cease  to  waste,  to  interrupt  disinte- 
gration, tQput  out  the  ^^fire^*  even  for  a  moment,  is  to 
cease  to  live ;  it  is  irrevocable  death.  Nor  can  repara- 
tion, or  even  primary  assimilation,  proceed  without  its 
twin  process— destruction.  Admitting  all  this  as  abun- 
dantly established  by  both  analogy  and  observadon, 
there  is  still  every  corroboratory  assurance,  in  both.cheiD- 
istry  and  physiology,  that  the  element  under  considera- 
tion is  less  a  /^/structive  than  a  ^^^str^ctive  agent,  less  a 
detergent  than  an  diment,  less  a  burn^  than  a  kuUdor^ 

Again,  the  underlying  idea  in  all  rational  .therapeutic 
endeavors,  aside  from  surgpk:al  conservation  of  structure 
and  the  temporary  palliation  of  excessive  pain,  is  to 
hasten  metamorphosis,  both  destructive  andconstrucdve, 
smce  it  is  universally  recog^nized  that  destructivet  acti<Ai 
r— eliminatiQa,  depuration — ^is  but  one  and  a  very  essen- 
tial part  of  constructive  change.  It  is  the  thrusting 
aside  of  obstacles  which  impede  or  bar  the  progress  of 
true  repair  and  rebuilding. 

.  On  the  part  of  those  who  have  been  in  the  habit  of 
thinking,  teaching,  ctnd  acting  in  the  old  rut^-for  rut.  it 
osAainly  is — it  will  take  some  time  to  fiiUy  comprehepd, 
and  will  require  a  considerable  effort  to  frankly  adnk 
this ;  for  the  rut  has  long  been  revered  as  the  regular 
way,  and  in  it  we  have  always  had,  and  still  have,  plenty  of 
company,  and  that  of  eminence  the  most  unquestioned. 
Nor  is  It  any  novelty,  (»  in  the  slightest  degree  an  in- 
novation, to  assert  this.  Acknowledged  authorities  in 
physio-diemistry  have  all  along  taught  it.  Jt  will  be  |i 
surprise  to  even  well-read  and  experienced  members  of 
the  profes^on  to  refer  freshly,  in  the  fiice  pf  this  asser- 
tion, to  standard  works  on  physiology .  and  see  how 
strong  and  positive  is  the  evidence  to  this  effect-r-evi- 
dence  which  most  of  us  have  all  along  blundered  over, 
ignored,  or  but  half  comprehended. 

*'  To  describe  fully  the  physiological  action  of.' oxygen 
would  involve  a  description  of  the  processes  of  respira- 
tion, sanguification,  nutrition,  and  tissue-change,  for  to  aU 
these,  and  to  life  itself,  it  is  essential."  * 

'^  Preyer  showed  that  a  greater  saturation  from  oxygen 
inhalation  is,  a  priori^  probable,  ....  and  Demar* 
quay  proved  it  by  showing  that  suppurating,  indolent,  or 
unhealthy  wounds  on  the  extremities  of  animals  became 
quickly  florid  and  hyper^emic  when  pure  oxygen  was  in- 
baled.  .  .  .  Allen  and  Pepys,  and  later  Limousin, 
showed  that  by  inhaling  an  equal  quantity  of  atmos- 
pheric air  at  one  time  and  oxygen  at  another  double 
the  amount  of  carbonic  acid  was  expired,  and  this  in- 
crease continued  for  fifteen  minutes  after  the  inhalations 
had  finished." 

*'  Other  observers  have  reported  that  the  elimination 
of  uric  acid  during  a  course  of  oxygen  inhalation  is 
markedly  lessened,  ;>.,  that  more  complete  combustion 
occurs  within  the  system  (Schmidt's  Jahrb.,  t  i.,  s.  aS, 
1865)."  • 


»  Journal  of  Insanttv,  rol.  xxix.,  p.  333. 

*  Phillips :  Mater.  M«d.  and  Tberapcutioi  vol.  L,  p.  3,  ed.  Wood*i  libnury . 
Z882. 

*  Phillipt,  op.  cit,  p.  5. 


286 


THE  MEDICAL  RECORD. 


[September  13,  1884. 


Kollman  foand  that  the  quantity  of  uric  acid  in  an 
equal  amount  of  urine  was  reduced  nearly  fifty  per  cent, 
by  free  oxygen  inhalation.  In  one  experiment  the 
amount  of  acid  fell  from  one  hundred  and  thirty-four  to 
twenty-five  milligrammes. 

Gublefs  experiments  proved  that  active  inspiration  of 
pure  oxygen  gas  slowed  the  pulse  and  respiratory  move- 
ments, produced  a  general  sense  of  comfort,  did  not 
cause  dyspnoea,  and  that  the  pause  between  inspiration 
and  expiration  could  be  prolon^d  from  the  ordinary 
limit  of  thirty  to  as  much  as  ninety  or  one  hundred 
seconds  after  breathing  oxygen  ;  and  as  a  result  of  his 
observations,  he  asserts  that  the  blood  receives  the  gas 
in  proportion  to  its  physical  capacity  for  it,  rather  than  in 
proportion  merely  to  the  vital  necessity  of  hsematosis. 
The  globules  absorb  what  they  need,  while  any  excess 
circulates  free  and  enters  into  combination  only  as  the 
haemoglobin  loses  oxygen  in  passing  through  the  capillaries. 

Quinquaud,  by  certain  chemical  tests,  which,  to  make 
them  reliable,  need  corroboration,  estimated  that  the 
capacity  of  the  blood  for  oxygen  in  healty  subjects  was 
quite  uniformly  two  hundred  and  forty  cubic  centime- 
tres of  oxygen  to  every  one  thousand  grammes  of  haemo- 
globin. 

The '  experiments  of  Buckheim,  Klebs,  Husemann, 
Naoumoff,  Beliaieff,  Savory,  Richardson,  Ewald,  Hering, 
aiid  others,  have  not  given  us  much  additional  light  on 
the  subject.  They  were  chiefly  of  that  crude,  forced, 
and  unnatural  character,  too  common  in  physiological 
experiments,  which  &dds  so  little  to  our  practical  knowl- 
edge of  the  "action"  of  any  remedv  when  property  ex- 
hibited. For  example,  what  would  it  profit  the  patholo- 
gist to  learn,  by  cruel  experiment  on*  the  lower  animals, 
or  perhaps  on  some  helpless,  hospitiil-stranded  human 
wtetch,  that  an  exclusive  diet  of  absolute  alcohol  pro- 
duced a  train  of  untoward  symptoms  and  speedy  death  ? 
Would  we  therefore  proscribe  all  the  alcoholic  mixtures — 
brandy,  gin,  wine,  whiskey,  etc.,  etc.  ? 

Nature  doeii  not' suggest  the  use  of  oxygen  in  a  "pure 
lind  nascent  state,"  as  used  by  these  experimenters,  and 
I  do  not  consider  such  use  of  the  -i^nt,  unmixed  and 
undiluted,'  permissible,  much  less  advisable,  except  in'  a 
few  emergencies,  and  then  only  to  cover  the  exigencies 
of  the  particular  cases  as  presented.  Hence  I  have 
little  interest  in-  the  class  A  experiments  referred  to. 
Tests  of  the  gas  as  a  therapeutic  agent  must  be  based  on 
conditions  which  do  not  do  viotenceto  weU-knawn  and  well* 
proved  ncUural  laws.  The  safe  guides  in  this,  as  in  all 
therapeutic  investigations,  are  common-sense,  the  recog- 
nition of  known  facts,  and  the  simple  rules  of  analogy. 
Above  all,  we  must  "take  a  hint  from  nature." 

Among  the  acute  or  immediate  conditions  which  oxy- 
gen and  its  congeners  can  be  made  to  promptly,  safely, 
and  surely  relieve,  may  be  cited  asphyxia^  from  drowning, 
hanging,  or  fiiom  inhaling  carbon  dioxide  or  other  Jios^ious 
gases ;  suspended  animation^  from  syncope  and  from 
opium  or  chloroform  narcosis  ;  poisoning,  from  various 
toxic  agents ;  spasmodic  asthma  (the  paroxysm);  ob'- 
structed  respiration,  as  in  diphtheritis  and  membranous 
croup  ;  and  in  cyanosis,  from  whatever  cause. 

Of  the  many  chronic  conditions  which  may  be  con- 
fidently attacked,  I  may  specifically  mention  anamia 
(Birch,  Demarquay,  Da  Costa,  Dujardin-Beaumetz,  et 
at.);  chlorosis  (idem);  the  cachexice  and  dyscrasice  in 
general ;  all  the  indigestions  and  dependent  disorders 
(Hill,  Beddoes,  Birch,  Goolden,  et  aL) ;  struma  and 
tuberculosis  (omnescit.)  ;  empyctmia;  cYixomc  glandular 
enlargements ;  intra-thoracic  and  intrc^pelvic  abscesses 
and  degcnercUions  \  epilepsy ;  emphysema  (palliative)  ; 
CLsthma  (curative)  ;  the  typhoid  state  ;  zymosis,  septiccemia, 
and  paludal  poisoning ;  neurasthenia,  and  nearly  all 
forms  of  neuralgia. 

From  this  imperfect  generalization,  it  will  not  be  diffi- 
cult for  the  observant  medical  mind  to  discern  the  special 
indications  and  contraindications  for  treatment  in  any 
given  case. 


It  may  be  asserted,  in  general,  on  rational  as  well  as 
experimental  grounds,  in  connection  with  this  treatment, 
that  those  chronic  cases  show  most  marked  and  striking 
results  which  are  selected  from  the  gfeat  army  of  house- 
prisoners,  "  delicate  "  people  who,  from  necesaty,  habit, 
preoccupation,  or  negligence,  have  been  long  deprived 
of  wholesome  air  and  everything  like  active  out-door 
life  ;  or  who  have  long  suffered  from  miasmatic  location, 
sedentary  occupations,  or  unsanitary  surroundings ;  or 
from  those  who  have  been  too  tenderly  reared— over- 
coddled  (and  this  virtually  includes  every  close  resi- 
dent of  a  populous  city).  To  these  may  be  added  the 
phlegmatic,  the  "lymph-albuminous,"  and  the  lazy~of 
whom  every  community  shows  numerous  examples— 
patients  witii  sluggish  circulation,  small  respiratoiy  ap- 
paratus, torpid  or  enlarged  livers,  fatty  heart  or  kidneys, 
and  with  habitually  retarded  excretory  functions  gener- 
ally. 

As  far  as  individual  experience  with  oxygen  goes-- my 
first  cases  were  treated  sixteen  years  ago — I  have  found 
thoroughly  satisfactory,  and  in  some  instances  very  remark- 
able, results  in  cases  of  inveterate  asthma.  As  a  paUiar 
tive  of  the  immediate  attack,  a  mixture  of  oxygen  and 
nitrogen  monoxide  has  invariably  given  instant  and  happy 
relief;  and  the  continued  use  of  the  two,  variously  mod- 
ified, has  never  failed,  in  my  hands,  to  effect  a,  to  all  ap- 
pearances,  complete  and  perfect  "  cure."  If  more  ex- 
tended  trial  proves  equally  successful,  the  treatment  might 
very  properly  be  termed  a  "  specific  "  in  the  treatment  of 
this  distressing  malady,  which  so  often  resists  all  ordinary 
as  well  as  extraordinary  measures. 

In  the  severer  forms  of  the  indigestions  the  resulufaave 
been  scarcely  less  brilliant  Scanty  or  suppressed  secre- 
tions are  gradually  restored,  absorption  and  assimilation 
resume  normal  activity,  and  the  functions  of  depuration 
and  defecation,  long  deranged,  obstructed,  or  interrapted, 
are  surely,  normally,  and  in  a  medical  sense  permanently 
restored.    * 

Hill's  first  experiments  with  oxygen  (i8so)  covered 
cases  of  hydrocephalus,  epilepsy,  chronic  arthritis 
(gouty?),  paralysis,  and  morbus  coxarius.  In  each  of 
these  he  reported  flatteringly  encouraging  results. 

Another,  by  no  means  unimportant,  but  as  yet  almost 
wholly  ignored  use  for  oxygen,  is  in  connection  with  tbe 
administration  of  anaesthetics.  On  purely  rational 
grounds,  as  well  as  from  some  years  of  practical  experi- 
mentation, I  am  thoroughly  convinced  that  the  dangers 
heretofore  presumed  to  be  inseparable  from  the  use  of 
ether,  chloroform,  and  other  anaesthetics  can  be  reduced 
to  a  minimum,  if  not  rendered  altogether  nil,  by  the 
timely,  previous,  and  perhaps  occasionally  subsequent 
exhibition  of  oxygen.  A  few  inspirations  of  the  gas, 
slightly  dihited,  taken  just  before  inhaling  chloroform  or 
other  anaesthetic,  while  it  does  not  interfere  with  the  de- 
gree of  anaesthesia  produced,  effectually  prevents  the 
usual  untoward  symptoms-^nausea,  headache,  delirium, 
etc.  And  while  not  materially  abbreviating  the  stage  of 
complete  anaesthesia,  it  shortens  the  recovery  stage  and 
effectually  forestalls  die  S3rmptoms  of  imminent  danger 
which  so  frequently  alarm  the  operator  and  jeopardize 
the  life  of  the  patient. 

In  the  use  of  nitroeen  monoxide  as  an  anaesthetic  in 
short  surgical  operations,  dentistry,  etc.,  the  effects  are 
much  more  desirable  when  a  certain  percentage  of  pure 
oxygen  is  added. 

On  this  point  I  would  quote  a  summary  of  results  ar- 
rived  at  by  Dr.  Klikowitsdi  after  a  series  of  experiments 
in  Prof.  Botkin's  laboratory,  at  St.  Petersburg  ( Virchavfs 
Archiv)  :  * 

1.  Anaesthesia  induced  by  it  [nitrogen  monoxide]  is 
closely  associated  with  insufficient  oxidation  of  the  blood, 
and  hence  not  absolutely  free  from  danger. 

2.  The  association  with  it  of  twenty  per  cent,  of  pure 
oxygen  completely  removes  all  possibility  of  asphyxia, 
without  interfering  with  the  completeness  of  the  anaes- 
thesia. 


September  13,  1884.  J 


THE  MEDICAL  RECORD. 


287 


3.  By  the  use  of  this  mixture  the  heart-pulsations  of 
healthy  subjects  are  increased,  the  pulse-wave  diminished, 
respiration  increased  in  depth  but  decreased  in  frequency ; 
these  effects  lasting  from  three  to  five  minutes. 

4.  In  four  cases  of  weak  heart-action,  the  exhibition  of 
this  mixture  produced  no  unfavorable  symptoms.  On  the 
other  hand,  the  pulse  increased  in  strength  and  decreased 
in  frequency;  these  effects  lasting  from  one  to  two 
hours. 

5.  In  cases  of  disturbed  respiratory  innervation,  the 
mixture  rapidly  removed  the  symptoms  of  deficient 
blood-oxidation  and  re|;ulated  the  respiratory  rhythm. 

6.  This  mixture  quickly  relieves  suffering  in  angina 
pectoris,  and  when  pushed,  produces  very  perfect  tran- 
sient ansesthesia. 

7.  It  is  preferable  to  chloroform  as  an  anaesthetic  in 
labor. 

8.  Vomidng  and  cough  of  reflex  origin  are  arrested  by 
a  few  inhalations  of  these  mixed  gases. 

(To  be  continued.) 


A  PLEA  FOR  THE  ARTIFICIAL  FEEDING  OF 
INFANTS  WITH  COWS'  MILK.' 

By  JOHN  BINNIE,  M.D., 

POYNBTTB,  WIS. 

I  ADMIT  that  nothing  is  equal  to  a  healthy  mother's  breast ; 
I  as  truly  believe  that  manv  a  mother's  milk  is  not  so 
good  as  proper  artificial  feedmg,  and  I  would  recommend 
irtificial  feeding  more  frequently  did  I  not  know  the 
great  liability  to  carelessness  on  the  part  of  the  niurse  in 
causing  sickness,  and  even  the  death  of  the  child.  My 
experience  has  been  quite  extensive,  but  entirely  with 
cows'  milk,  except  in  two  cases,  where  we  added  an 
infant  food.  I  can  say  nothing  of  the  various  prepared 
foods  and  milks  sold  by  the  trade.  As  I  live  in  a  healthy 
agricultural  district  of  Wisconsin,  among  mixed  nation- 
^ties,  I  advise  the  selection  of  a  good  healthy  cow, 
between  the  age  of  four  and  ten  years,  of  mild  disposi- 
tioD,  which  has  been  ^ving  milk  from  four  to  eight 
weeks  previous  to  the  birth  of  the  child. 

The  selection  made,  she  should  be  cared  ibr  as  follows, 
mil  fed  on  good  clean  grain,  and  hay  free  from  must  Roots, 
if  any  are  fed,  should  be  of  good  quality,  and  she  should 
have  plenty  of  good  clean  water  from  a  living  spring  or  well* 
Her  pasture  sSK>uld  be  Timothy  grass  or  native  grass,  free 
from  weeds ;  clover  alone  is  bad.  When  mixed  with 
other  grasses  it  will  do.  She  should  be  cleaned  and  cared 
for  like  a  carriage-horse  and  milked  twice  a  day.  In  a 
few  instances,  during  the  very  hot  weather,  I  have  recom- 
mended milking  three  times  a  day.  The  milking  is  al- 
ways to  be  done  at  the  same  time  and  by  the  same 
person.  This  is  very  important,  as  those  having  experi* 
ence  with  cows  will  readily  understand.  The  milk 
should  be  kept  in  a  cool  place,  away  from  v^etableS  of 
all  kinds,  or  any  odors,  as  milk  is  exceedingly  sensitive 
to  all  such  agents.  You  must  caution  the  nurse  to  be 
especially  careful  during  thunder-storms,  as  milk  mil  sour 
then  do  what  you  will. 

Further,  I  believe  some  cows  are  unfit  by  nature 
for  feeding  infants.  In  feeding  the  infant  everything 
connected  with  the  utensils  must  be  kept  scrupulously 
dean.  Take  three  or  four  parts  of  warm  water  to  one 
part  of  milk,  and  a  little  fine  white  sugar ;  bring  all  to  the 
temperature  of  the  body.  Give  the  child  about  two 
ounces  every  two  or  three  hours.  This  strength  is  gen- 
erally sufficient  for  the  first  two  or  three  months,  when 
you  will  gradually  increase  the  proportion  of  milk,  so 
that  by  the  time  the  child  reaches  four  months  it  will 
be  taking  milk  and  water  about  equal  parts,  and  an  in- 
aeased  quantity.     These  are  general  remarks,  and  may 


*Read  beCwe  the  Columbia  Coanty  Medical  Society,  July  31,  1884,  held  in 
Portage. 


require  changing  to  suit  individual  cases.  No  absolute 
rule  can  be  laid  down  that  will  be  suitable  to  all  cases. 
The  condition  of  the  child  must  be  the  guide.  Should 
the  child  appear  to  be  insufficiently  nourished,  increase 
the  quantity  of  milk  to  water,  or  use  barley-water  in 
place  of  simple  water,  especially  so  if  any  tendency  to 
diarrhoea  is  present.  I  have  seen  cases  of  diarrhoea  from 
too  much  water  yield  at  once  to  an  increase  in  the  pro- 
portion of  milk  and  the  substitution  of  barley-water. 
You  will  also  get  diarrhoea  from  too  great  a  proportion 
of  milk,  or  if  the  quantity  taken  be  too  great ;  the  physi- 
cian must  be  on  his  guard  to  determine  which  cause  is 
operating  in  the  individual  case.  When  the  food  is  too 
rich,  the  diarrhoea  generally  follows  immediately  upon 
some  change  that  has  been  made  in  its  food,  or  the 
child  may  become  fleshy  at  first.  And  this  misleads 
both  the  nurse  and  physician ;  they  reason  that  the  child 
has  been  doing  better  since  the  last  change  in  its  food. 
In  these  cases  we  often  see  preceding,  or  simultaneous 
with,,  the  onset  of  diarrhoea  a  crop  of  red  raised  spots  on 
the  face  or  extremities,  or  both,  of  the  child.  This,  with 
the  fact  that  it  had  increased  rapidly  in  adipose  tissue 
for  a  time,  should  call  our  attention  to  its  food  as  being 
too  rich  or  too  great  in  quantity.  It  may  call  for  an 
examination  of  the  ^condition  of  the  cow  or  her  pasture. 
I  believe  pure  clover  very  liable  to  produce  this  eruptive 
condition  of  the  child. 

The.  dangers  from  overfeeding,  whether  by  too  large 
a  proportion  of  milk,  or  too  ^eat  a  quantity  given,  are 
greater  than  the  opposite  conditions,  especially  so  during 
hot  weather.  The  cases  are  rare  where  the  child  caii 
take  pure  milk  with  safety  before  the  ninth  month,  and 
according  to  my  experience  not  before  the  year. 

I  think  well  of  b^ley-water  during  the  heat  of  summer 
and  at  any  time  wh^n  a  tendency  to  diarrhoea  exists>  ai^ 
I  doubt  not  it  niight  be  of  service  in  the  opposite  con- 
dition. 

An  infant  fooKi,  added  to  the  inilk  as  bi^ore  pre-, 
pAJred,  did  well  in  my  two  cases.  As  before  stated,  the 
condition  of  the  child  is  the  best)  guide.  When  doing 
well,  let  it  alouQ  and  make  as  few  changes  as  possible.. 
Increase  very  gradually  the  strength  of  its  food. 

I  do  not  allow  any  solid  food  until  after  a  number  of 
teeth  are  through.  Np  table-feeding  of  any  kind.  I 
have  seen  children  fed  as  above  never  sick  a  day^  and  as 
healthy  as  any  I  ever  saw  nurse  a  mother.  I  have  seen 
the.'  opposite  from  a  violation  of  the  rules  continue  un 
til  the  nurse  became  more  careful.  Such  carelessness 
on  the  part  of  a  nurse  ought  not  to  condemn  artificial 
feeding.  I  am  fully  persuaded  that  a  child  can.be  raised 
with  as  much  certainty  of  living  as  when  iiursing  the 
mother,  if  the  necessary  care  is  taken.  The  causes  of 
fisulure,  as  I  have  found  them,  are : 

1.  Want  of  cleanliness  of  the  utensils. 

2.  Carelessness  in  the  preparation  of  the  food,  as  to 
the  exact  proportion  of  milk  and  water,  at  each  meal. 

.  3.  The  want .  of  regularity  as  to  time  and  quantity  of 
feeding. 

4.  Changing  from  one  cow's  milk  to  another,  or  using 
mixed  milks  of  different  cows. 

5.  Allowing  the  child  to  nurse  or  drink  too  rapidly. 
The  slower  the  food  can  be  taken  without  tiring  the  child 
the  better.  Making  any  of  the  above  mistakes  may  pro- 
duce derangement,  while  some  children  are  permitted  to 
violate  them  all  and  live,  thus  proving  the  exception 
to  the  rule. 

I  have  not  written  this  either  to  recommend  or  con- 
demn any  artificial  foods,  or  in  any  way  to  detract  from 
the  value  of  them ;  but  I  have  thought  there  wais  a  ten- 
dency among  some  of  the  profession  to  make  the  arti- 
ficial feeding  of  infants  altogether  too  artificial,  and  to 
try  and  supplant  milk  entirely,  or  give  it,  to  say  the  least, 
a  secondary  place.  This  cannot  be  done  successfully. 
We  had  better  devote  more  time  and  money  to  getting 
pure  fresh  milk  ;  then,  if  thought  best,  add  your  artificid 
foods. 


288 


THE   MEDICAL  RECORD. 


[September  13,  1884. 


A  CASE  OF  TRAUMATIC  TETANUS  CURED 
BY  THE  INTERNAL  AND  LOCAL  USE  OF 
SULPHATE  OF  MORPHINE. 

By  J.  W.  STICKLER,  M.S.,  M.D. 

OKAVGi^  «.   J. 

On  June  4,  1884,  I  was  called  to  see  T J—, 

aged  eight  years.  In  attempting  to  cut  some  hay  in  one 
of  the  old-fashioned  hay-cutters,  he  brought  the  knife 
down  upon  his  left  middle  finger,  about  midway  between 
the  tip  and  the  first  joint  As  the  cut  seemed  to  extend 
about  half  through  the  finger  I  thought  it  would  be  wise  to 
endeavor  to  save  the  part  by  carefully  coapting  the  cut 
surfaces.  To  do  this  I  inserted  a  few  fine  sutures.  The 
wound,  however,  did  not  unite,  suppuration  causing  the 
surfaces  to  separate.  As  it  was  manifestly  useless  to 
again  attempt  to  save  the  end  of  the  finger,  I  determined 
to  amputate  at  the  first  joint.  In  this  operation  I  was 
assisted  by  Dr.  J.  Y.  Simpson.  The  flaps  united  quickly, 
and  the  boy  did  very  well  till  June  i8th,  when  he  devel- 
oped tetanoid  S3rmptoms.  He  had  pain  along  the  anterior 
attachment  of  the  diaphra^  and  in  his  back,  difficulty 
in  swallowing,  and  spasmomc  contractions  of  the  muscles 
about  his  mouth.  His  lower  extremities  were  at  once 
placed  in  a  hot  mustard  badi,  hot  poultices  applied  to 
his  abdomen,  and  a  mustard  plaster  to  the  back  of  his 
neck.  He  was  then  given,  per  orera,  nix.  of  Magendie's 
solution  of  morphine,  and  wrapped  in  a  blanket.  The 
following  day  there  were  firequent  contractions  of  the 
muscles  of  the  face,  throat,  and  trunk ;  pain  in  the  epi* 
sastric  region  was  quite  distressing ;  swallowing;  of  solid 
food  was  difficult,  even  water  excited  a  mild  spasm 
of  the  throat  muscles.  At  this  stage  of  the  disease  I 
asked  Dr.  Wm.  Pierson  to  see  the  case,  in  consultation. 
He  suggested  the  application  to  the  part  of  pooltices 
containing  morphine  (gr.  j.  each).  He  was  also  given 
twice  daily  (9  a.m.  and  4  p.m.)  twenty-five  to  thirty-five 
drops  of  Magendie's  solution  of  morphine,  per  orem,  the 
dose  varving  within  the  limits  named,  to  suit  the  e#Mr* 
gency  of  the  case.  Large  flaxseed  poultices  were  om- 
stantiy  applied  to  his  back  and  abdomen,  and  he  was 
carefully  shielded  from  draughts.  After  beginning  thb 
treatment  there  was  sufficient  opisthotonus  to  muce  it 
possible  to  pass  the  hand  and  forearm  between  the  bed 
and  the  patient's  back.  This  condition  lasted  about 
seventy-two  hours.  The  mouth  at  that  time  could  not 
be  opened  wide  enough  fo  admit  the  index  fin^r.  His 
food  consisted  of  milk  and  broths.  Constipation  was  a 
troublesome  complication,  requiring  the  occasional  use 
of  croton-oil  in  one-drop  doses. 

By  degrees  the  rigidity  of  the  various  muscles  dis- 
appeared, the  patient  being  restored  by  July  xst  to  a 
normal  condition,  so  far  as  the  use  of  the  various  parts  of 
his  body  was  concerned. 

Malarial  Gastralgia. — Dr.  N.  O.  D.  Parks,  of 
Ashton,  R.  I.,  writes :  *'  The  following  case  may  prove 
interesting  as  an  example  of  the  hydra-headed  manner  in 

which   malaria  manifests  itselfl      K.   H ,  a  young 

married  woman,  has  been  subject  to  severe  attacks  of 
gastralgia  since  the  birth  of  her  first  child  about  ten 
months  ago,  when  they  occurred  for  the  first  time,  and 
have  been  hitherto  amenable  to  treatment.  She  had  one 
on  June  7th,  and  called  in  a  physican  who  administered 
morphine  hypodermically.  I  was  sent  for  June  loth. 
She  seemed  to  derive  no  benefit  from  morphia,  vibur- 
num, Hoffmann's  anodyne,  nor  any  of  the  usual  remedies, 
external  or  internal,  the  paroxysms  apparently  subsiding 
of  themselves  after  the  lapse  of  four  or  five  hours,  to  re- 
turn with  increased  violence,  at  first  every  other  day,  but 
finally  they  recurred  every  morning,  accompanied  by  vom- 
iting, which  brought  no  relief.  This  periodicity  led  me 
to  administer  quinine  in  full  doses,  which  promptly 
aborted  the  attacks.  After  three  days  I  lessened  the 
amount  of  quinine,  and  prescribed  arsenic  in  small  doses, 
and  she  has  had  no  recurrence  of  the  malady." 


ON  MURIATE  OF  LIME. 
By  JOHN  C.  PETERS,  M.D., 

MBW  YOBK. 

Some  time  ago  Ths  Medical  Record  had  a  very  sugges- 
tive  article  on  the  *'  Uses  of  the  Muriate  of  Lime."  I  have 
found  additional  material  in  the  works  of  the  late  Dr.  I. 
Warburton  Begbie.  In  small  and  repeated  doses  it  pro- 
duces increased  secretion  of  mucus,  urine,  and  perspira* 
tion  ;  in  large  doses  it  is  irritant.  Fourcroy  and  many 
physicians  of  his  time  (1775-1809),  had  mudi  confidence 
in  it  against  scrofula,  but  especially  the  celebrated  Dr. 
Beddoes,  who  gave  it  to  nearly  one  hiudred  patients,  in 
doses  of  ten  drops  of  the  saturated  solution  to  young 
children,  up  to  two  drachms  to  adults,  three  or  four  times 
a  day.  He  says  there  are  few  of  the  common  forms  of 
scrofula  in  which  he  has  not  had  successful  experience 
with  it  He  gives  the  case  of  a  boy,  aged  seven  years, 
with  a  voracious,  almost  insatiable  appetite,  protuberant 
belly,  diarrhoea,  emaciation,  hectic  fever,  and  nigfat 
sweats,  who  recovered  in  two  months  after  taking  ten- 
drop  doses,  gradually  increased  to  forty ;  which  he  took 
with  pleasure  in  small  beer  or  coffee.  The  purging  stopped 
first,  and  then  the  hectic  fever.  Also  the  case  ot  a  young 
lady,  aged  thirteen,  with  the  same  symptoms,  and  in  ad- 
dition, swelled  feet,  cough,  and  difiicult  respiration.  In 
three  days,  after  taking  twenty-drop  doses,  increased  to 
sixty,  the  purging  stopped ;  in  nine  days  the  feet  ceased 
to  swell,  while  tiie  hectic  symptoms  and  oou^h  disap- 
peared in  tiiree  weeks,  foUowed  by  recovery  with  great 
gain  in  flesh  in  six  weeks.  Dr.  Begbie  sajrt  be  has  often 
cured  similar  cases,  especially  the  chrooic  diarrhoDa  of 
young  children  when  associated  with  hectic  fever  and 
tumid  belly. 

Dr.  James  Wood  says  he  wonkl  feel  in  some  degree 
accountable  for  the  sufferings  of  all  thus  diseased  U  he 
did  not  make  its  virtues  known.  He  used  it  largely  in 
incipient  phthisis,  in  all  the  fonns  of  scrofula,  and  in 
hectic  fever  fit>in,  or  with  great  dischaqpe^  Dr.  logn^ 
bam  found  it  to  possess  great  (x>wers  in  discussing  tumon 
and  obstructions  of  various  kinds.  The  opinions  of  Dr. 
James  Sanders  have  already  been  given  in  The  Record. 

Dr.  James  Hamilton,  professor  of  midwifay  in  Edin- 
burgh, speaks  of  it  in  hig^  terms  in  scroAila,  and  Dr. 
Antiiony  Todd  Thompson  asserts  that  he  has  seen  naore 
benefit  from  its  continued  use  than  from  any  other  medi- 
cine. Dr.  John  Thomson  refers  to  the  three  muriate^ 
those  of  soda,  baryta,  and  Ume,  in  scrofiila,  but  seemed 
to  prefer  cod-liver  oil  and  iodine. 

Begbie  has  used  it  most  successfully  in  struma,  marked 
by  enlargement  of  the  glands  of  the  neck,  after  iodine, 
iodide  of  potash,  and  iron  and  cod-liver  oLL  had  fail^; 
and  says  it  is  in  his  power  to  assert  that  many  instances 
of  very  great  enlargement  of  the  cervical  glands  have 
yielded  to  its  use ;  also  in  glandular  swellings  of  the 
axillae  and  inguinal  regions,  and  of  the  deep-seated  lym- 
phatics of  the  pelvis.  It  often  Requires  to  be  taken  for 
a  considerable  time,  for  weeks  or  even  months,  before 
its  beneficial  effects  are  visibly  produced,  Usually,  how- 
ever, in  the  course  of  a  few  weeks  there  occurs  a  cer- 
tain degree  of  softening  in  the  glandular  tumors,  and  tb^ 
component  glands  of  the  mass  are  more  easily  distinguish- 
able. With  the  gradual  subsidence  of  the  enlargement 
there  is  a  notable  improvement  in  the  patient  as  to  ap- 
pearance, appetite,  and  digestion.  If  the  remedy  is 
stopped  too  soon,  relapses  may  occur.  He  has  often 
given  the  medicine  with  the  greatest  regularity  for  one  or 
two  years.  He  thinks  it  is  best  taken  in  milk,  but  some 
prefer  water.  It  has  a  mawkish,  disagreeable  taste,  which 
is  partiy  or  wholly  concealed  by  milk,  but  many  gnulually 
acquire  a  liking  for  it  and  have  a  great  disinclination  to 
stop  it. 

Dr.  Begbie  gives  the  case  of  a  young  woman,  with  a* 
really  frightful  disfigurement  of  the  neck,  who  was  de- 
cidedly improved  in  three  months,  and  was  in  a  very 
satisfactory  state  in  a  month  more.     He  refers  to  two 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


289 


others.  In  many  cases  the  disorder  will  return  slightly 
after  the  muriate  of  lime  is  stopped,  but  invariably  yields 
again  to  the  remedy,  and  then  the  cure  is  permanent 

In  tabes  mesenterica,  with  protracted  diarrhoea  and  ex- 
haosting  perspirations,  the  medicine  is  equally  useful, 
causing  a  subsidence  of  the  hectic  fever,  an  improvement 
of  appetite,  a  gaining  of  flesh  and  strength,  and  a  gradual 
restoration  to  health.  In  grave  disorders  of  the  bowels 
it  arrests  diarrhoea,  promotes  digestion,  and  favors  nutri- 
tion. Also  in  a  class  of  cases  marked  by  depraved  appe- 
tite, loss  of  flesh,  pallor,  protuberant  belly,  wasted  limbs, 
and  more  or  less  febrile  excitement  of  an  intermittent  or 
remittent  hectic  type,  with  two  distinct  paroxysms  of 
fever  every  day.  It  checks  purging,  lessens  the  fever, 
allays  the  mordinate  appetite,  and  ultimately  restores  the 
patient  to  health.  The  red  appearance  of  the  tip  and 
edges  of  the  tongue  fades  away,  and  the  nausea  ceases. 
It  acts  quicker  than  lime-water. 

It  has  proved  useful  in  lupus  exedens  and  non-exedens, 
in  local  pforiasis,  in  some  instances  of  ozsna,  and  in 
chronic  tonsilitis.  The  recognized  dose  is  ten  to  twenty 
grains.  The -Edinburgh  solution  has  ten  grains  in  every 
fifteen  drops,  which  is  the  average  dose  for  a  young  adult, 
to  be  given  three  times  a  day  in  milk.  Gradually  the 
doses  may  be  increased  to  thirty  or  forty  drops.  It 
lessens  the  acidity  of  the  urine  remarkably.  All  these 
good  effects  Dr.  Begbie  has  noticed  again  and  again.  y*j 


ACUTE  IMPULSIVE  INEBRIETY. 
By  T.  D.  CROTHERS,  M.D., 

HAKTVORI^  CONN. 

This  term  describes  a  class  of  cases  who  suddenly  use 
alcohol  to  great  excess,  either  for  a  definite  period,  or 
constantly  until  death  or  dementia  terminates  their  con- 
ickms  existence.  In  many  cases  they  are  closely  allied 
to  acute  mania,  and  merge  into  it,  but  although  of  the 
same  family  group,  there  are  distinct  differences.  Clini- 
cally two  classes  are  prominent,  and  both  begin  the  same 
way,  but  after  a  time  they  diverge  widely.  In  one  the 
use  of  alcohol  is  continuous,  and  only  varied  by  the  diffi- 
culty of  procuring  it,  and  Ac  change  to  opium  or  other 
narcotics.  In  the  other  a  distiqct  free  interval  of  sobriety 
follows,  usually  of  definite  length,  which  becomes  shorter 
as  the  disease  progresses.  The  latter  is  of  a  dipsomaniac 
tjrpe,  with  epileptic  tendencies,;and  may  at  last  become 
what  has  been"  erroneously  termed  ^alcoholic  epilepsy. 
Criminality  and  many  strange  psychical  manifestations 
appear  in  this  class.  The  first  class  of  continuous 
drinkers  are  marked  by  the  early  and  profound  failure 
of  all  the  higher  brain  qualities,  dropping  quickly  from 
positions  of  character  and  reputation  to  that  of  moral 
imbecility,  and  apparent  unconscious  realization  of  duty 
and  obligation  to  others.  My  object  is  to  trace  some  of 
the  apparent  causes  and  symptoms  of  the  early  premoni- 
tory stage  of  this  affection.  These  cases  have  no  par- 
ticular stage  of  moderately  drinking,  or  period  in  which 
wine,  beer,  bitters,  or  other  of  the  milder  alcoholic  drinks 
are  used.  They  begin  at  once  with  poisonous  excessive 
doses  of  alcohol  Despite  all  theories  it  is  an  unmistak- 
able fact  that  this  condition  is  an  explosion,  or  the 
bnrstmg  into  activity  of  a  long  train  of  causes  unnoticed 
before.  It  is  a  sign  of  brain  exhaustion,  of  diseased  con- 
ditions that  have  suddenly  concentrated  into  a  craving 
for  the  narcotic  effects  of  alcohol.  This  uncontrollable 
desire  for  alcohol  or  other  narcotics  is  a  symptom  of 
profound  disease  and  degeneration,  which  may  be  regarded 
from  two  points  of  view,  namely,  as  a  congenital  or  ac- 
quired condition. 

In  ttie  first,  or  inherited  group,  I  find  such  cases  as  the 
following :  A  man  of  good  health,  temperate,  and  of  repu- 
jation,  who  has  insane  or  inebriate  ancestors,  but  who 
MS  lived  an  exemplary  temperate  life,  drinks  suddenly 
to  great  excess  and  never  recovers.  It  may  follow  some 
business,  losses  or  social  disasters,  and  in  many  cases  it 


comes  on  without  the  slightest  reason  that  is  apparent, 
like  a  lightning-fiasl\  in  the  clear  sky.  Another  case 
would  be  of  some  hard-working,  business,  or  professional 
man,  who  has  given  signs  of  nerve  and  brain  failure  f6r 
years,  then  all  unexpectedly  lapses  into  profound  ine- 
briety. An  epileptic  neurosis  or  consumptive  and  hys- 
teric diathesis  is  found  to  be  present. 

In  other  cases  signs  of  brain  defects  from  heredity  are 
present.  Thus  a  passionate,  unreasoning,  impulsive  brain 
power ;  or  a  brain  on  the  borders  of  delusions  and  hal- 
lucinations ;  or  a  changeable,  uncertain  brain  force,  ex- 
hibiring  many  hints  of  defect  will  suddenly  develop  into 
inebriety.  Some  writers  assert  that  in  such  cases  in- 
ebriety is  merely  an  outlet  for  insanity,  or  insanity  in  an- 
other form,  which  would  appear  with  certainty  in  the 
natural  progress  of  the  case.  This  would  be  expected 
if  a  state  of  moderate  drinking  was  present,  but  in  such 
cases  absolute  abstinence  from  all  use  of  spirits  exists  up 
to  the  moment  of  the  outbreak.  In  some  cases  these 
apparent  inherited  nerve  defects  are  obscure  and  un- 
noticeable,  except  from  an  intimate  acquaintance,  and 
the  outburst  of  inebriety  cannot  be  traced  to  any  pres- 
ent exciting  cause ;  the  only  fact  of  significance  is  that 
diey  had  an  insane  or  inebriate  and  neurotic  ancestry. 
A  vast  realm  of  clinical  and  psychological  facts  stretch 
out  from  this  point  entirely  unknown. 

Another  group  of  cases  who  have  a  decided  neurotic 
ancestry,  and  themselves  exhibit  marks  of  it  in  their 
actions  and  thoughts,  become  impulsive  inebriates  from 
distinct  causes  that  are  traceable.  Thus  a  temperate 
man  of  this  class  will  suffer  some  great  loss  of  property, 
or  of  relatives  bv  death ;  will  meet  some  unexpected 
disaster,  which  will  profoundly  impress  and  change  all 
his  functional  activities.  After  a  short  incubating  period 
he  will  begin  to  use  spirits  to  great  excess,  either  in 
secret  or  openly.  A  prominent  governor  of  a  great 
State,  temperate  and  robust  in  mind  and  character,  whoste 
father  was  a  hard-drinking  man,  was  suddenly  over^ 
wtnkned  with  sorrow  at  a  social  wreck  in  his  family. 
Three  days  after  he  went  to  his  stable  with  a  case  of 
brandy,  and  drank  to  excess  for  four  days,  concealed  by 
his  hostler.  From  this  time  he  has  continued  to  drink 
at  intervals,  without  control  of  himself  or  without  con- 
scious reason,  and  is  now  a  confirmed  inebriate  invalid. 

In  another  case  of  a  man  of  prominence,  with  an  in- 
ebriate ancestry,  sudden  bankruptcy  through  the  dis- 
honesty of  partners  precipitated  him  into  impulsive  and 
profound  inebriety,  ending  fatally  in  a  few  months  from 
acute  pneumonia.  In  these  cases  prominent  exciting 
causes,  particularly  great  strains  and  profound  emotionsu 
changes,  have  fanned  into  activity  a  latent  neurosis,  iHiich 
otherwise  might  have  remained  dormant. 

The  same  results  are  seen  in  cases  who  suffer  from 
some  acute  disease  that  is  profound  and  prolonged,  such 
as  typhoid  fever,  malaria,  pneumonia,  pleurisy,  gastritis, 
and  many  other  diseases  which  positively  affect  the  in- 
tegrity of  the  organism,  leaving  an  entailment  or  condi- 
tion of  debility  from  which  recovery  is  very  slow.  In 
such  cases,  particularly  where  inebriate  heredity  is  pres- 
ent, impulsive  inebriety  may  spring  up  and  go  on 
rapidly  to  death.  A  favoring  soil  is  present,  and  some 
unknown  germ  cause  has  developed  it.  An  almost  end- 
less variety  of  conditions,  involving  every  form  of  strain 
and  drain,  of  fimctional  and  organic  activities,  starting 
from  a  defective  brain  and  nerve  soil  merge  into  this 
malady.  In  the  acquired  form  or  group  the  same 
conditions  are  seen  without  the  apparent  heredity.  It 
would  seem  that  all  the  conditions  have  grown  up  from 
neglect  and  the  surroundings.  A  common  illustration  is 
seen  in  the  constantly  increasing  army  of  business  men 
who  steadily  overwork,  and  neglect  to  obey  the  simplest 
laws  of  health,  thus  becoming  more  and  more  unfitted  for 
the  trials  and  duties  of  life.  Suddenly,  after  some  great  loss 
and  strain,  they  become  inebriates  and  drink  without  any 
intelligent  reason  why  they  do  so.  The  class  who  have 
used  alcohol  in  moderation  for  a  long  time,  and  suddenly 


290 


THE  MEDICAL  RECORD. 


[September  13,  1884^ 


become  pronounced  inebriates,  are  very  common  in  all 
large  cities.  Bat  the  brain-workers,  who  are  intemperate 
in  almost  everything  except  the  ule  of  alcohol  (in  this 
they  are  total  abstainers^,  are  furnishing  an  increasing 
proportion  of  cases  of  this  form  of  inebriety.  A  man 
who  occupies  a  position  as  a  worker  and  producer,  who 
is  a  power  in  his  circle,  suddenly  poisons  himself  with 
alcohol,  and  keeps  it  up  day  after  day  until  death  brings 
relief. 

If  the  causes  are  not  traced  to  heredity,  they  will  be 
found  in  some  condition  of  bad  living  overwork,  want 
of  rest,  and  imperfect  nutrition.  Psychical  traumatism  is 
apparent  in  a  certain  number  of  these  cases.  As  an 
illustration,  lately  prominent  in  a  distant  city.  A  cler- 
gyman, a  total  abstainer,  a  man  of  unusual  force  of  char- 
acter and  health,  saw  his  daughter  dashed  down  an  em- 
bankment and  killed.  The  next  day  after  he  drank  to 
intoxication,  and  is  to-day  a  periodical  inebriate  of  the 
worst  type.  In  another  case  a  man  of  repute  was  in- 
toxicated at  the  funeral  of  his  wife  and  never  recovered. 
In  a  case  under  my  care  a  temperate  man  began  to 
drink  to  great  excess  on  the  sudden  return  of  his  son, 
who  was  supposed  to  have  been  killed  on  the  battle-field. 
In  other  instances  the  mental  shock  from  sudden  pov- 
erty or  unexpected  wealth  have  resulted  in  this  form  of 
inebriety. 

Undoubtedly  some  profound  change  and  alteration 
takes  place  in  the  central  nerve  system,  followed  by  psy- 
chical pain  and  exhaustion,  for  which  nothing  but  alcohol 
brings  relief.  In  these  cases  a  substratum  of  inherited 
degeneration  may  favor  this  state,  or  condition  of  impair- 
ment from  disease  or  other  cause,  which  intensifies  the 
inebriety,  making  it  more  incurable. 

Many  of  these  cases  of  acute  impulsive  inebriety  are 
concealed  with  most  extraordinary  judgment  on  the  part 
of  the  victim.  He  has  become  a  periodical  inebriate, 
and  from  symptoms  he  anticipates  the  approach  of  the 
paroxysm,  and  conceals  himself  from  observation  until 
the  drink  storm  has  passed.  Such  cases  leave  work  sud- 
denly, and  very  strangely  disappear  from  the  circles  of 
their  acquaintances,  and  a  few  days  or  weeks  later  return, 
paler  and  somewhat  worn,  and  resume  work  as  before. 
This  concealment  may  go  on  for  years,  or  until  death 
comes  from  some  acute  disease.  Frequently  sexual  per- 
versions are  associated  with  this  disorder ;  then  the  victim 
will  be  found  in  disreputable  houses  far  away  from  home. 
Usually  this  class  seek  quiet  hotels  in  the  interior,  or  pri- 
vate asylums  under  assumed  names.  Others  appear 
boldly  in  public  places  and  at  home,  and  seem  to  have 
lost  all  pride  of  appearance,  and  when  efforts  are  made 
to  restrain  them  from  the  drink  used,  resort  to  any  sub- 
rstitute,  and  usually  find  some  form  of  opium  or  prepara- 
ition  of  chloral  equally  satisfactory. 

In  a  certain  number  this  form  of  inebriety  is  followed 
by  paralysis  in  a  year  or  more,  showing  that  it  was  but 
an  early  state  of  other  disease.  In  other  cases  dementia 
appears,  and  the  drink  craving  subsides.  In  others  opium 
and  chloral  inebriety  come  on,  from  which  recovery  is 
rare.  The  prognosis  is  unfavorable.  The  craving  for 
alcohol  may  die  out,  but  other  diseases  will  follow.  In 
many  cases  acute  tuberculosis  follows,  and  in  all  instances 
general  failure  of  all  the  functions  point  to  the  gravity  of 
this  affection. 

Prompt,  early  recognition  of  disease  and  diseased  con- 
ditions are  demanded  in  all  these  cases.  Questions  of 
vice,  will-power,  and  morals  are  absurd ;  medical  means 
and  remedies  are  wanted  ;  for  no  matter  what  the  case 
may  be  in  other  respects,  it  is  a  distinct  neurosis  that  re- 
quires po^tive  practical  methods  of  treatment 

The  quarantine  of  an  asylum  or  hospital  is  needed, 
where  every  condition  of  surroundings  can  be  under 
control,  and  where  every  source  of  irritation  that  is  re- 
movable can  be  reached. 

The  work  of  restoration  involves  long  time  and  every 
appliance  of  science  and  art  which  can  be  brought  to 
build  up  and  strengthen  the  brain  and  nerves.     If  the 


case  has  merged  into  a  periodical  condition,  the  parox- 
ysms must  be  anticipated  in  the  treatment,  and  all  means 
used  to  abort  and  lessen  their  intensity. 

In  some  instances  these  periods  return  with  great  ex- 
actness, which  can  be  anticipated  within  a  day  or  hour. 
Then  the  value  of  hospital  treatment  and  medical  aids 
are  indispensable.  Many  instances  are  on  record  of 
persons  able  to  realize  the  approach  of  these  paroxysms^ 
and  who  place  themselves  under  control  or  in  favorable 
conditions  to  pass  them  with  the  least  injury.  One 
such  instance  is  that  of  a  temperance  lecturer  who  be- 
came an  inebriate  from  the  loss  of  his  property,  followed 
by  acute  meningitis  and  inebriety.  He  lectures  on  tem- 
perance during  the  free  interval  between  the  drink  par- 
oxysms. These  return  at  intervals  of  ninety  days,  rarely 
ever  exceeding  this  time  more  than  a  day.  After  a  time 
he  is  conscious  of  the  approach  of  these  paroxysms,  in 
certain  nervous  symptoms,  and  goes  to  jail  and  is  locked 
up  in  a  cell  for  a  week,  being  fed  on  beef-tea  and  milk. 
Later,  he  went  to  a  hospital ;  then,  as  the  paroxysms 
grew  less  he  could  be  restrained  in  a  private  house  or 
hotel  with  the  door  locked  and  his  clothes  removed 
Now,  five  years  later,  the  paroxysm  still  returns,  with 
the  same  regularity  as  to  time,  and  he  goes  to  some  re* 
tired  place  where  he  can  be  locked  in  ;  has  his  clothes 
taken  away,  and  drinks  large  quantities  of  milk,  and 
uses  a  bromide  prescription  of  about  two  hundred  grains 
a  day  for  two  days  or  more.  After  a  week  he  fully  re- 
covers and  resumes  work  again  for  ninety  days  more. 
Here  the  quarantine  of  a  hospital  is  absolutely  essential ; 
nothing  but  restraint  will  enable  him  to  pass  this  critical 
point. 

The  continuous  inebriate  of  this  class  needs  not  only 
restraint,  but  change  of  surroundings  both  mental  and 
physical.  He  is  exhausted,  and  must  be  built  up ;  his 
mind  must  be  turned  to  other  channels,  and  all  the  sur- 
roundings must  be  stimulating — brain  rest,  muscle  rest, 
nerve  rest,  freedom  from  all  strains  and  drains — these 
are  the  comer-stones  of  treatment. 

These  cases  are  not  dipsomaniacs ;  for  in  nearly  all 
instances  there  is  no  delusion  or  hallucinations  ;  the  de- 
sire for  alcohol  is  the  craving  for  relief ;  for  a  condition 
of  psychical  pain  or  agony  that  is  most  positively  checked 
by  alcohol.  If  this  drug,  is  not  obtainable,  other  com- 
pounds are  used.  If  opium  in  any  form  had  been  at 
hand,  and  its  first  effects  pleasant  at  the  beginning,  it 
would  be  used  in  preference  to  alcohol.  It  is  not  alco- 
holism, for  the  use  of  this  drug  is  only  a  symptom  of 
other  and  more  serious  trouble.  The  desire  for  alcohol 
is  fully  satisfied  when  certain  effects  are  obtained. 

These  cases  are  unrecognized  except  in  the  most  vague, 
general  way.  Then  simply  as  drunkards  who  have  oc- 
cupied better  positions,  and  are  now  noted  for  what  is  i 
termed  depravity  and  great  changes  of  character  and  ' 
purposes  of  life.  Physicians  who  are  called  to  treat 
some  extreme  stage  of  these  cases  recognize  a  realm  of 
psychological  mystery  which  they  are  unable  to  solve. 
Thus  the  case  goes  on  down  to  death,  unknown  and 
unrecognized,  and  of  course  nearly  all  the  means  and 
remedies  that  are  used  intensifying  the  very  conditions 
they  seek  to  lessen. 

In  a  summary  of  what  is  known,  the  following  may  be 
stated  as  a  grouping  of  outline  facts  : 

J^irs/, — Acute  impulsive  inebriety  appears  in  persons 
previously  temperate,  who  have  not  used  alcohol  before. 
It  is  marked  by  profound  precipitation  and  rapid  degener- 
ation both  mentally  and  physically. 

Second: — All  cases  can  be  traced  to  congenital  and 
acquired  conditions,  both  of  which  are  combined  in  some 
cases.  Certain  causes  are  found  to  be  peculiarly  ex- 
citing, and  this  form  of  inebriety  follows  with  great  ccr- 
tainty.  All  cases  merge  into  periodical  or  continuous 
drinking. 

Third, — In  the  treatment  means  of  prevention  and 
means  to  conduct  the  case  to  a  successful  termination  in 
recovery  should  be  sought.     Quarantine  hospitals  are 


September  13,  1884.  J 


THE  MEDICAL  RECORD. 


291 


essential,  together  with  all  other  means  which  science 
and  art  can  suggest. 

p9urih, — ^These  cases  should  receive  thorough  medical 
study,  and  all  means  for  relief  should  be  based  on  such 
study  and  its  conclusions. 

Wholesale  Poisoning  by  Illuminating  Gas. — 
An  account  is  given  by  Dr.  G.  £.  Bentzen,  in  the 
Nffrdiskt  MedicinsJU  Arkivj  vol.  xvi.,  No.  i,  1884,  of 
the  poisoning  of  all  the  inmates  of  a  house  by  illuminat- 
ing gas.  The  house  was  three  stories  in  height  and  con- 
tained sixteen  rooms,  occupied  by  six  families,  but  there 
was  no  gas  supply  and  not  a  single  gas-pipe  in  the  house. 
There  had  been  a  break  in  the  gas-main  in  the  street,  and 
from  this  the  gas  passed  through  several  feet  of  earth 
into  the  cellar,  and  was  thence  diffused  through  the 
whole  house  in  such  quantity  that  every  inmate  suffered 
in  nearly  equal  degree.  The  author  cites  the  circum- 
stance as  showing  how  readily  the  emanations  from  the 
soil  may  pass  up  into  the  different  sleeping  apartments 
on  the  several  floors  of  a  dwelling. 

Embouc  Infarction  of  Muscles. — ^That  the  mus- 
cles, like  other  organs,  are  liable  to  be  the  seat  of  em- 
tx>]ic  infarctions  is  a  subject  which  is  discussed  by  M. 
Girandeau  in  a  recent  article,  and  he  thinks  that  the 
rarity  of  this  event  is  attributable  partly  to  the  fact  that 
the  muscles  are  seldom  examined  post  mortem,  and 
partly  (probably  mainly)  to  the  readiness  with  which 
coUaterad  circulation  is  established  in  cases  of  blockage 
of  a  muscular  artery.  It  is  different  in  the  case  of 
pyaemia,  where  muscular  metastatic  abscesses  are  fre- 
quent ;  but  in  ordinary  cases  of  cardiac  disease,  where 
the  viscera  show  ample  evidence  of  embolism,  there  are 
very  few  records  of  muscular  infarction.  Comil  and 
Ranvier,  admitting  this  rarity,  state  that  they  have  met 
with  two  instances,  and  that  they  were  characterized  by 
absence  of  hemorrhage.  Girandeau  supplies  notes  of 
three  cases.  The  first  was  a  case  of  chronic  mitral 
disease  with  general  atheroma.  The  right  sartorius 
muscle  was  found  to  be  ruptured,  the  broken  ends 
embedded  in  hemorrhagic  efiusion,  and  their  muscular 
fibres  granular.  The  spleen  contained  two  old  infarc- 
tions.  The  second  case  of  long  standing  mitral  and 
aortic  disease,  with  arterial  atheroma,  exhibited  a  firm, 
yellow-colored  mass  in  the  substance  of  the  pectoralis 
major  muscle,  sharply  marked  off  from  the  healthy  tissue, 
and  resembling  a  visceral  infarct.  The  spleen,  kidneys, 
and  brain  were  also  the  seat  of  embolism.  A  third  case, 
quoted  from  Lefevje^s  thesis  (1867^,  was  of  the  same 
class,  and  was  further  complicated  with  dry  gangrene  of 
the  left  foot  and  leg.  In  this  case  a  yellowi^  gray  mass 
of  degenerated  muscular  tissue  occurred  in  the  substance 
of  the  vastus  extemus  muscle.  These  three  cases  were, 
it  will  be  seen,  of  chronic  heart  disease,  and  Girandeau 
asks  whether  these  muscular  infarctions  could  not  also 
occur  in  the  course  of  acute  endocarditis  in  young  sub- 
jects. A  priori^  such  an  event  is  not  impossible ;  but 
some  experiments  made  by  him  at  Alfort  were  wholly 
native  in  their  result.  He  concludes  that  many  con- 
ditions may  be  necessary  to  the  production  of  the  event, 
among  which  he  enumerates  degeneration,  roughening, 
and  inelasticity  ^i  the  arteries ;  an  enfeebled  heart ;  and 
a  more  or  less  marked  asphyxial  condition,  impairing  the 
autrition  qf  the  muscle. — London  Lancet 

Ths  Gbnesis  of  Mblanamia. — Professor  Marchia- 
&va  and  Dr.  A.  Celli  have  recently  published  a  most  im- 
portant paper  {Memorie  della  R,  Accademia  del  Lincei) 
on  this  subject  ^ving  the  results  of  experiments  and 
researches  made  m  the  laboratory  of  pathological  anat- 
omy in  Rome — the  title  of  their  paper  being,  "The 
Alterations  of  the  Red  Blood-globules  in  Malarial  Infec- 
tion, and  the  Genesis  of  Melanaemia.'^     It  will  be  inter- 


esting, therefore,  to  learn  what  were  the  alterations  found 
The  method  used  for  examining  the  blood  was  as  fol- 
lows :  The  blood  was  taken  from  a  small  prick  in  the 
finger  of  the  fever  patient  in  different  stages  of  the  fever, 
the  finger  being  previously  washed  with  alcohol.  On  the 
drop  of  blood  thus  obtained  a  cover-glass  was  lightly 
pressed ;  it  was  then  pressed  against  another  glass,  and 
the  two  slipped  over  each  other  so  as  to  get  a  thin  film 
of  blood;  Uie  glasses  were  then  passed  through  the 
flame  of  a  spirit-lamp,  so  as  to  dry  them.  On  this  prep- 
aration one  or  two  drops  of  an  aqueous  or  alcoholic  solu- 
tion of  methylene-blue,  recently  filtered,  was  dropped ; 
it  was  then  washed  and  mounted.  By  this  method  the 
normal  red  globules  were  slightly  colored  blue,  unless 
the  coloring  matter  had  been  washed  out  too  soon. 
The  protoplasm  of  the  white  globules  was  colored  a 
pale  blue,  while  the  nucleus  took  a  deep  color.  In  an 
individual  affected  with  malaria,  however,  there  were 
found,  in  the  midst  of  the  normal  red  discs,  other  red 
globules  whose  protoplasm  was  altered,  this  being  very 
evident  in  those  discs  which  were  not  colored.  These 
alterations  consisted  in  the  presence  in  the  globules  Of 
small  corpuscles,  var3dng  in  number,  different  in  size 
and  form,  which  were  colored  blue  with  more  or  less 
intensity,  but  always  so  much  as  that  they  could  be  dis- 
tinguished from  the  protoplasm  of  the  red  disc,  whether 
colored  or  not.  These  corpuscles,  passing  frt>m  the 
smallest  to  the  largest  forms,  are  seen  as :  i.  Granules, 
generally  rounded,  which  are  usually  colored  a  more  or 
less  intense  blue,  and  somewhat  resemble  micrococci ; 
one  or  more  are  found  in  a  globule,  and  sometimes  one- 
third  of  the  red  disc  will  contain  one,  two,  or  more 
corpuscles.  2.  As  corpuscles  larger  than  those  just 
described,  with  the  appearance  of  rings  in  the  middle, 
which  may  occupy  a  third  or  one-half  of  the  red  disc 
3.  As  corpuscles  much  larger  than  the  first,  uniformly 
colored,  or  with  spaces  of  spherical,  ovoid,  fusiform  dr 
triangular,  which  generally  contain  granules  of  black 
pigment  in  the  centre.  The  larger  masses  invade,  in 
soiyie  red  discs,  all  the  protoplasm  colored  by  the  haemo- 
globin, of  which  only  a  -v&rj  small  portion  may  remain. 
With  these  red  discs,  thus  altered,  are  found  bodies 
colored  as  the  masses  above  described,  and  containing 
pigmentary  granules.  These  bodies  evidently  represent 
the  last  stage  of  alteration  of  the  red  disc,  which  is  thus 
converted  into  a  body  deprived  of  haemoglobin,  con- 
taining pigment  These  alterations  of  the  red  discs  may 
be  followed  in  all  their  stages  until  the  conversion  of 
them  into  pigmented  masses.  When  the  red  disc  con- 
tains one  or  more  pigmented  corpuscles  and  a  certain 
portion  of  its  colored  protoplasm  remains,  its  normal 
elasticity  seems  to  be  preserved ;  but  when  converted 
into  a  yellow  pigmented  body,  its  elasticity  may,  or  may 
not  be  retained,  and  the  disc  will  adhere  to  the  cover- 
glass  without  pressure.  Such  is  a  general  r^sumi  of  the 
microscopic  appearances  of  the  blood  in  malarial  sub- 
jects, especially  during  the  febrile  movement  Are  these 
alterations  always  found  in  malarial  infection  ?  In  some 
cases  the  altered  red  discs  are  few,  in  others  very 
numerous ;  in  others  still  they  cannot  be  found  at  all. 
But  this  is  true  not  only  in  cases  of  simple  intermittent, 
but  in  aggravated  cases  of  malarial  infection,  and  even  in 
the  forms  of  comatose  pernicious  fever.  Whtn  these  al- 
terations are  found  the  patient  always  has  a  peculiar 
yellowish  earthy  appearance,  the  feebleness  is  very  great, 
and  convalescence  is  more  slow,  and  restitution  to  health 
more  difficult  Important  information  might  be  gained 
by  studying  the  relations  between  the  degree  of  alteration 
of  the  blood  and  the  clinical  course  of  the  malarial  dis- 
ease. The  examination  of  the  fresh  blood  from  a  case  of 
algid  pernicious  fever  showed  the  presence  of  pigmenta^ 
tion  in  numerous  white  globules ;  the  red  discs  were  not 
altered.  After  coloring  by  the  method  indicated,  how- 
ever^ the  corpuscles  were  found  in  the  red  discs.  Micro- 
scopic examination  of  the  organs  and  blood  after  death 
showed  the  described  alterations ;  the  same  was  true  of 


292 


THE  MEDICAL  RECORD. 


[September  13,  1884. 


two  other  characteristic  cases  of  malarial  infection  ter- 
minating in  death.  From  this  it  seems  demonstrated 
that  in  malarial  infection  an  alteration  of  the  red  discs 
takes  place,  running  through  various  stages,  and  which 
commences  with  the  presence  of  granules  and  corpuscles, 
generally  spherical,  which  are  colored  by  aniline.  This 
process  is  continued  by  the  growth  of  the  corpuscles,  by 
their  fusion  and  the  formation  of  dark  pigment  in  the 
form  of  granules  and  masses,  and  terminates  with  the 
reduction  of  the  red  discs  into  a  yellowish  pigmented 
body  which  is  entirely  broken  up,  while  the  pigment  is 
freed  and  is  deposited  in  the  various  organs.  But  what 
is  the  nature  of  this  alteration  of  the  red  globules? 
Without  doubt  it  should  be  regarded  as  one  of  a  regres- 
sive nature,  or  better,  we  may  accept  Tommasi  Crudeli's 
view,  that  it  is  a  necrobiosis  of  the  red  disc,  which  is  now 
no  longer  a  red  globule,  but  a  circulating  body  incapable 
of  performing  its  normal  functions.  This  being  admitted, 
it  may  be  asserted,  as  regards  the  seat  of  the  formation 
and  the  genesis  of  the  pigment  of  melanaemia  :  i.  That 
the  pigment  is  formed  in  the  blood-vessels,  and  in  the 
circulating  blood ;  and,  2,  that  its  origin  is  the  coloring 
matter  of  the  red  disc,  and  that  it  is  formed  in  the  pro- 
toplasm of  this  disc.  The  first  conclusion  is  evident  if  it 
is  admitted  that  the  pigment  is  formed  in  the  circulating 
red  discs,  and  it  is  in  accordance  with  what  has  already 
been  shown  by  Kelsch  and  Arstein.  The  second  con- 
clusion is  not  less  evident,  since  the  dark  pigment  is  de- 
posited as  the  red  discs  are  decolorized,  and  aJl  the  stages 
of  this  loss  of  color  and  pigmentation  may  be  successively 
followed.  It  should  also  be  stated  that  in  certain  cases^ 
in  which  there  is  so  great  a  destruction  of  the  red  discs, 
there  are  also  found  nucleated  red  discs,  macrocytes,  and 
discs  differently  colored  from  those  ordinarily  found.  It 
is  well  known  that  nucleated  red  discs  are  not  found  in 
the  normal  extra-uterine  circulation,  except  during  the  first 
few  days  after  birth  ;  but  they  are  very  frequently  found 
in  essential  and  symptomatic  anaemia.  But  hitherto  they 
have  not  been  described  in  the  acute  stages  of  infection. 
Their  presence  in  acute  malarial  infection,  as  well  as  in 
the  periods  of  convalescence,  is  doubtless  directly  re- 
lated to  the  direct  destruction  of  the  red  discs,  and  is  a 
sure  indication  that  the  functions  of  the  haematopoietic 
organs  are  so  stimulated  by  the  destruction  of  the  discs 
that  they  are  manufactured  more  rapidly  than  is  neces- 
sary, and  are  thrown  out  into  the  circulation  before  they 
have  lost  their  nuclei.  These  experiments,  though  not 
yet  complete,  certainly  explain  the  alterations  of  the  red 
disc  caused  by  malaria,  and  go  far  toward  clearing  up 
the  genesis  of  melanaemia.  And  although  the  absence 
of  these  alterations  in  the  red  globules  does  not  exclude 
malarial  infection,  their  presence  proves  it  conclusively, 
as  they  have  been  found  in  no  other  disease. 

Treatment  of  Laryngismus  Stridulus. — In  a  clin- 
ical lecture  on  this  complication  of  rickets.  Professor 
Widerhofer  (Aligemeine  Wiener  Medicinische  Zeiiungy 
July  29,  1884)  recommends  traction  of  the  tongue  during 
the  attack,  to  prevent  closure  of  the  glottis,  or  sprinkling 
cold  water  in  the  face.  In  the  intervals  he  gives  bromide 
of  potassium,  and  regards  this  as  almost  a  specific  for 
these  spasmodic  attacks.  The  remedy  must  be  given  in 
rather  large  doses,  four  grains  morning  and  evening,  gradu- 
ally increased  to  eight  grains.  In  one  or  two  da3rs,  he 
claims,  the  attacks  will  have  wholly  ceased  to  occur. 

Death  from  Injection  of  Iodine  in  Spina  Bifida. 
— Dr.  Woltering  relates  the  following  case  in  the  Alige- 
meine Medicinische  Central-Zeitungy  August  13,  1884. 
He  first  operated  upon  the  chUd  when  she  was  four  days 
old,  simply  puncturing  the  sac  and  making  pressure  with 
adhesive  plaster  and  a  piece  of  lead.  All  went  well  for 
four  months,  but  the  parents  were  careless  about  keeping 
the  compress  properly  adjusted  and  the  tumor  reappeared. 
It  was  then  determined  to  use  iodine.  The  sac  was 
punctured  and  about  two  tablespoonfiils  of  clear  spinal 
fluid  evacuated.     One  tablespoonful  of  a  solution  con- 


taining seven  grains  of  iodine  and  twenty  grains  of  iodide 
of  potassium  to  the  ounce  of  water  was  then  injected. 
As  the  sac  was  filling,  it  was  noticed  that  the  diiid 
stopped  breathing.  The  solution  was  immediately  pressed 
out  again,  and  every  effort  made  to  resuscitate  the  child. 
The  heart  continued  to  beat  for  some  time,  but,  in  spite  of 
artificial  respiration  maintained  for  half  an  hour,  death 
could  not  be  averted.  This  case  well  illustrates  fthe 
danger  of  this  procedure,  immediate  paralysis  of  the  res- 
piratory  centres  having  followed  an  injection  of  only 
about  Uiree  grains  of  pure  iodine. 

Tuberculosis  of  the  Tonsils. — It  was  formerly  sup- 
posed that  tuberculosis  of  the  tonsils  never  or  at  most 
very  rarely  occurred.  In  order  to  determine  the  correct- 
ness of  this  supposition,  Dr.  F.  Strassmann  {Ceniralblatt 
far  Chirurgie^  August  16,  1884)  has  examined  these  or- 
gans  in  a  number  of  individuals  dead  of  tubercular  affec- 
tions. In  nearly  every  case  of  pulmonary  phthisis  he 
found  turbercles  in  the  tonsils,  while  in  those  who  had 
died  of  tuberculosis  of  other  organs  these  bodies  were 
healthy.  The  result  of  these  investigations  would  seem 
to  show  that  the  tonsils  become  infected  directly  by  the 
tuberculous  matter  in  the  sputa,  since  they  were  diseased 
only  in  those  cases  in  which  the  lungs  were  affected. 
Tuberculosis  of  the  tonsils  seldom  leads  to  extensive 
caseous  degeneration  or  destruction  of  the  organs.  Small 
miliary  tubercles  and  few  bacilli  are  found. 

Treatment  of  Pseudarthrosis. — In  a  monograph 
recently  published  in  St.  Petersburg,  Dr.  A.  Karmiloff 
reviews  tfie  different  methods  of  treatment  of  ununited 
fracture,  and  gives  the  indications  for  the  employment  of 
each.     He  regards  irritation  of  the  integument  by  iodine, 
blisters,  etc.,  as  of  no  value,  except  in  cases  of  retarded 
consolidation  merely.     The  method  of  rubbing  together 
the  ends  of  th^  bone  was  successful  in  about  10  per 
cent,  of  the  reported  cases.     It  is  indicated  only  in  those 
cases  in  which  the  opposing  ends  of  the  bone  are  thick 
and  lie  in  close  apposition.    This  procedure  is  not  al- 
ways a  safe  one,  and  has  sometimes  been  followed  by 
very  serious  consequences.    Dieffenbach's  method  of  in- 
serting ivory  pegs  has  resulted  successfully  in  43.5  per 
cent  of  operations  on  the  thigh  and  arm,  and  in  80 
per  cent,  of  operations  on  the  forearm  and  leg.    The  au- 
thor, however,  believes  this  percentage  is  too  high,  many 
failures  not  having  been  reported.     The  method  is  only 
useful  when  the  ends  of  the  bone  can  be  kept  firmly  in 
position,  and  when  the  tissues  respond  readUy  to  sli|;)it 
irritation.     Electro-puncture,  the  subcutaneous  mjecuon 
of  chemical  irritants,  the  insertion  of  needles  into  the  tis- 
sues between  the  ends  of  the  bone,  and  the  pinning  to- 
gether of  the  fragments,  are  all  procedures  that  the 
author  regards  with  some  favor,  but  which  he  considers 
less  effectual  than   Dieffienbach's  method.     When  the 
ends  of  the  bone  lie  near  each  other,  are  perfectly  mova- 
ble and  thinned  down,  and  when  the  tissues  seem  to  have 
lost  the  power  of  bone  formation,  Dr.  Kamiiloff'  regards 
resection  as  clearly  indicated.     The  resected  ends  are  to 
be  held  in  close  apposition  by  splints  or  suture. — Cen- 
tralblatifUr  Chirurgiey  August  9,  1884. 

The  Cause  of  Puerperal  Septicemia. — In  a  com- 
munication addressed  to  the  Soci6t6  des  Sciences  M^- 
cales  of  Lyons,  M.  Arloing  (Lyon  MidUcU^  August  3, 
1884)  claims  to  have  isolated  the  microbe  of  puerperal 
septicaemia.  The  organisms  are  micrococci  united  in 
the  form  of  long  chains  looking  at  first  sight  like  bacilli 
Inoculations  of  rabbits  with  cultures  of  the  microbe  caused 
death  with  symptoms  of  septic  poisoning.  In  some  cases 
fibrinous  peritonitis  was  found  after  death.  He  con- 
cludes, firom  the  experiments  made  by  him,  that  the  dif- 
ferent forms  of  puerperal  septicaemia  are  caused  by  the 
same  agent,  the  particular  form  of  the  disease  being  due 
to  the  degree  of  activity  of  the  microbe.  Yet  he  does 
not  maintain  that  this  micro-organism  is  peculiar  to  the 
puerperal  state,  but  only  that  at  this  time  the  conditions 
are  favorable  to  its  introduction  and  development 


September  13, 1884.] 


THE  MEDICAL  RECORD. 


293 


SaKROsis  IN  Plaques  following  Infectious  Dis- 
SASES.—According  to  Dr.  Marie,  infectious  diseases, 
such  as  typhoid  fever,  small-pox,  pneumonia,  syphilis, 
Qtc,  may  give  rise  to  consecutive  paralyses  caused  by 
scUrose  en  plaques.  The  author  reports  twenty  cases 
taken  from  various  sources.  This  view  of  the  nature  of 
paralysis  occurring  during  convalescence  is  somewhat 
novel  and  needs  further  confirmation  before  being  ac- 
cepted.— Revista  Clinica  e  TerapeutUa^  August,  i884« 

Honey  as  a  Remedy  for  Small-pox. — A  physician 
of  Arequipa,  Peru,  writes  to  a  local  journal  in  praise  of 
the  virtues  of  honey  in  the  treatment  of  small-pox.  A 
child  was  attacked  with  what  threatened  to  be  a  ver}'  se- 
vere form  of  the  disease,  but  to  the  surprise  of  all  began 
to  mend  within  a  few  days,  and  passed  through  a  speedy 
convalescence  without  any  complications.  In  searching 
for  a  cause  of  this  unusually  rapid  recovery,  it  was  found 
that  the  patient,  whenever  left  alone  by  his  nurse,  had 
helped  himself  to  some  honey  which  was  standing  in  a 
jar  near  his  bed.  The  remedy  was  then  tried  in  two  other 
cases  occurring  at  about  the  same  time,  and  with  equally 
£ivorable  result  The  writer  seemed  to  think  that  there 
was  something  more  than  a  mere  coincidence  in  these 
cases,  and  hoped  that  others  would  make  a  trial  of  this 
toothsome  remedy  in  order  to  prove  its  efficacy. — La 
Or'mUa  Midica^  August  5,  1884. 

Treatment  of  Enlarged  Prostate. — M.  Tripier  di- 
rects attention  to  the  possibility  of  reducing  prostatic 
congestion  by  £u'adization.  One  electrode  is  to  be  in- 
trodyced  into  the  urethra  and  the  other  into  the  rectum. 
He  has  also  had  recourse  to  simple  intra-rectal  faradiza- 
tion.  The  sittings  are  of  five  minutes'  duration,  and  the 
strength  of  the  current  is  to  be  so  as  to  cause  no  pain. 
For  hypertrophy  of  the  prostate  the  author  makes  use  of 
suppositories  of  one  and  a  half  grain  of  iodide  of  potas- 
sium and  one-tenth  grain  of  muriate  of  morphia. — Lyon 
MUical^  August  3,  1884. 

The  Coni>ition  of  the  Ovaries  during  Men- 
struation.— Dr.  Meyer  has  made  a  number  of  bimanual 
examinations  of  the  ovaries  during  the  menstrual  period 
to  determine  vdiat  changes  they  undergo  at  this  time. 
In  some  cases  he  found  an  evident  increase  in  size,  in 
some  no  change  was  discoverable.  While  these  organs 
are  usually  of  a  firm  consistence,  during  menstruation 
they  are  found  to  be  elastic.  In  some  cases  the  ovaries 
were  of  a  more  rounded  form,  in  others  there  were 
mequalities  on  the  surface  of  the  organ.  Sometimes  he 
could  observe  no  change  in  shape,  and  sometimes  there 
were  changes  in  both  organs,  or  again  in  only  one. — 
Lyon  MkOceU^  August  10^  1884. 

The  Action  of  Phosphorus  upon  the  Fcetus. — 
Dr.  Igacushi  Moritzi  Miura,  of  Japan,  has  been  conduct- 
ing some  experiments  on  rabbits  and  guinea-pigs  to  de- 
termine whether  phosphorus  given  to  the  mother  induces 
any  changes  in  the  fcetus.  He  found  fatty  degeneration 
of  the  liver  in  the  mother  thirty  to  forty  hours  after 
poisoning  with  phosphorus,  and  the  same  condition,  but 
less  marked,  in  the  foetus.  He  found  gastro-adenitis  in 
the  foetus  as  well  as  in  the  mother.  Hence  he  concludes 
that  phosphorus  given  to  the  mother  can  pass  through 
the  placenta  and  exert  its  injurious  effects  upon  the  fcetus 
also. — Centralblatt  far  Klinische  Medicin^  July  26,  1884. 

Pernicious  ANiEMiA  in  Children. — Dr.  Kjellberg 
relates  the  case  of  a  child  five  years  old  who  was  seized 
rather  suddenly  with  headache  and  general  languor.  At 
the  same  time  the  skin  became  of  a  pale  yellow,  waxy 
appearance,  the  lips  were  pale,  and  the  countenance  had 
the  appearance  of  suffering,  although  the  body  remained 
plump.  Soon  he  had  dyspnoea  on  the  slightest  exertion, 
palpitation  of  the  heart,  an  anaemic  murmur  was  audible 
in  the  vessels  of  the  neck,  and  there  were  hemorrhages 
into  the  retina  and  under  the  skin.  The  blood  was  pale 
in  color,  and  the  number  of  red  blood-corpuscles  fell 
away  firom  900,000  to  571,000  per  cubic  millimetre. 


Death  followed  in  six  weeks,  in  spite  of  arsenic  exhibited 
in  moderate  dose.  At  the  autopsy  there  was  extensive 
fatty  degeneration  of  the  heart,  the  brain  was  very 
anaemic,  and  the  kidne3rs  were  fatty.  There  was  no  en< 
largement  of  the  liver,  spleen,  or  lymphatic  glands. 
This,  the  author  says,  is  the  second  case  of  pernicious 
anaemia  in  childhood  that  is  known  in  pediatic  litera- 
tiure. — Centralhlatt  fUr  Klinische  Medicin,  July  26,  1884. 

Diagnosis  of  Apparent  Death.— The  temperature 
of  the  skin  in  the  living  subject  always  rises  during  con- 
traction of  the  muscle  lying  immediately  beneath,  but 
after  death,  even  during  the  time  that  the  muscular  con- 
tractility to  electrical  stimulus  is  preserved,  this  increase 
of  heat  does  not  occur.  Dr.  Max  Buch  sees  in  this  a 
valuable  sign  by  which  it  can  be  determined  whether  life 
is  extinct.  The  thermometer  is  to  be  placed  upon  the 
integument  before  and  after  muscular  contraction  has 
been  excited  by  electricity,  and  if  the  mercury  does  not 
rise  at  the  second  trial  he  regards  the  patient  as  certainly 
dead. — Deutsche  Medicinal-T^itung^  No.  37,  1884. 

Miliary  Aneurism  of  the  Stomach. — Dr.  Gallard 
has  had  an  opportunity  of  seeing  three  cases  of  haema- 
temesis  firom  the  rupture  of  miliary  aneurisms  of  the 
stomach  (Deutsche  Medicinal-Zeiiung^  No.  37,  1884). 
The  first  case  was  that  of  a  man,  fifty-one  years  of  age, 
who  was  suddenly  seized  with  severe  hemorrhage  from 
the  stomach  and  bowels.  He  had  never  suffered  from 
any  gastric  trouble.  Death  occurred  in  a  few  days,  and 
at  the  autopsy  there  was  found  a  small  tumor  the  size  of 
a  millet-seed,  in  which  there  was  a  little  opening  plugged 
with  a  clot  of  blood.  It  was  ascertained  by  injection 
that  this  tumor  was  formed  by  an  enlargement  of  a  branch 
of  the  coronary  artery.  A  month  later  Dr.  Gallard  re- 
ceived another  patient  who  had  suffered  for  two  days  from 
severe  hsematemesis.  There  was  no  history  of  a  previous 
,  affection  of  the  stomach.  At  the  autopsy  the  same  con- 
dition was  found  as  in  the  first  case.  The  third  patient 
had  been  seized  while  upon  the  street  with  hemorrhage 
from  the  stomach.  He  had  for  a  few  days  complained 
of  loss  of  appetite  and  pain  in  the  epigastrium.  The  next 
nig^t  the  patient  died,  and  at  the  autopsy  there  was  seen 
a  tumor  the  size  of  a  bean  on  the  greater  curvatiure  near 
the  cardiac  orifice.  There  was  a  perforation  at  the  apex 
of  the  tumor  through  which  the  blood  had  escaped.  The 
tumor  lay  directly  over  a  small  artery,  but  attempts  at 
injection  failed.  The  only  case  similar  to  these  that  has 
been  reported  is  one  of  Dr.  Douglas-PoweL  But  here, 
however,  there  was  a  tubercular  ulceration  of  the  stomach, 
so  that  the  aneurism  could  only  be  regarded  as  of  sec- 
ondary origin. 

Antipyrin  in  Diseases  of  Children. — Drs.  Pen- 
zoldt  and  Sartorius  have  made  a  number  of  trials  of  anti- 
pyrin in  the  treatment  of  children's  diseases,  and  report 
the  following  conclusions  in  the  Berliner  Klinische 
Wachenschr^  of  July  28,  1884 :  i.  Antipyrin  is  to  be 
regarded  as  a  very  effectual  remedy  in  the  pyretic  dis- 
eases of  childhood.  2.  In  suitable  dose  it  lowers  the 
temperature  several  degrees,  and  the  effects  continue  for 
several  hours.  3.  The  pulse  rate  is  never  reduced  in  a 
degree  corresponding  to  the  fall  of  temperature.  4.  The 
effect  upon  the  general  condition  is  usually  good.  5. 
The  only  disturbances  that  it  ever  causes  is  occasionally 
vomiting.  When  this  occurs  the  remedy  may  be  given 
by  the  rectum.  6.  Antip3nin  should  be  given  in  three 
doses  at  intervals  of  an  hour.  Each  dose  should  consist 
of  as  many  decigrammes  (one  and  a  half  grain)  as  the 
child  has  lived  years.  If  this  dose  is  insufficient,  as  may 
often  be  the  case  in  small  children,  it  should  be  increased 
a  decigramme  at  a  time  until  the  desired  effect  is  obtained. 
When  administered  by  the  rectum,  a  single  dose  of  from 
thr«e  to  six  times  as  many  decigrammes  as  the  child  counts 
years  may  be  given.  7.  When  the  use  of  the  drug  has 
been  long  continued  the  organism  seems  at  times  to  be- 
come tolerant,  and  then  the  dose  must  be  increased  cau- 
tiously. 


294 


THE  MEDICAL  RECORD. 


[September  13,  1884. 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &.  Co.,  Nos.  56  and  58  Lafayette  Place. 

New  York,  September  13,  1884. 

PROFESSOR  VIRCHOW'S  ADDRESS  ON  META- 
PLASIA. 

We  have  received  from  our  correspondent  in  Copen- 
hagen the  full  text  of  Professor  Virchow's  address  before 
the  International  Medical  Congress,  and  are  enabled  to 
supplement  the  necessarily  brief  cabled  report  by  a  more 
complete  abstract  of  the  lecture.  After  referring  to  the 
older  theories  concerning  the  nature  of  the  vital  pro- 
cesses in  health  and  disease,  the  author  stated  briefly  his 
doctrine  of  cellular  pathology  and  showed  how  it  opposed 
Schwann's  theory  of  the  origin  of  cells  from  the  blastema. 
The  old  theory  of  the  identity  of  growth  and  nutrition  is 
manifestly  untenable.  The  end  and  aim  of  nutrition  is 
self-preservation,  while  that  of  growth  is  increase  of  cells. 
When,  in  the  latter  process,  two  cells  are  formed  from 
one,  the  old  cell  disappears,  and  thus  we  see  that  the 
plastic  process,  although  productive,  is,  in  a  certain  sense, 
also  destructive.  Thus  there  is  a  contradiction  between 
the  nutritive  or  trophic  and  the  formative  or  plastic  pro- 
cesses, which  no  amount  of  reasoning  upon  the  materials 
affecting  nutrition  and  growth  can  explain  away.  Be- 
cause the  sande  matter  is  used  at  one  time  for  nutrition 
and  at  Another  for  the  increase  of  cells,  it  in  no  way  fol- 
lows that  the  processes  in  the  two  cases  are  identical, 
and  still  less  that  the  cause  of  both  nutrition  and  growth 
resides  in  this  matter.  All  organic  activity,  the  speaker 
insisted,  resides  within  the  cells.  There  is  a  wide  differ^ 
ence  between  cellular  nutrition  and  the  nourishment  of 
the  individual.  The  former  only  begins  where  the  latter 
ends.  Living  tissues  may  take  up  materials  without 
using  them  in  nutrition,  as,  for  instance,  the  intestinal 
epithelium,  and  the  hepatic  cells  take  up  fat  during  the 
process  of  digestion,  but  they  soon  give  it  off  again.  In 
the  process  called  assimilation,  in  which  the  cells  take 
up  matters  from  the  fluids  and  then  form  them  into  the 
necessary  tissue  materials,  nutrition  and  growth  seem  to 
approach  each  other  ;  but  yet  there  is  a  distinction.  The 
formation  of  tissue  materials  from  nutritive  materials  is 
indeed  a  sort  of  plastic  process,  but  the  latter  term  must 
be  more  strictly  limited  to  express  the  setting  forth  of 
new  elements,  a  formation  of  new  cells.  Growth  itself 
includes  two  processes,  which  must  be  kept  distinct  one 
from  the  other.  There  is  hypertrophy,  an  increase  in 
size  of  the  individual  cells,  and  hyperplasia,  a  true  new 
formation  whether  of  cells  or  nuclei ;  the  one  belongs  to 
trophic,  the  other  to  plastic  processes. 

But  there  is  another  group  of  processes,  more  nearly 


related  to  the  plastic  than  to  the  nutritive,  and  yet  not  in 
a  strict  sense  plastic,  as  no  new  elements  are  formed 
This  is  what  the  author  called  metaplasia,  the  distinguish- 
ing mark  of  which  is  the  persistence  of  the  cells  while  the 
character  of  the  tissue  is  changed.  Although  metaplasia 
is  the  basis  of  many  important  pathological  processes,  it 
is  not  pathological  per  se.  We  see  it  exemplified  in  the 
formation  of  the  bony  framework  of  the  body.  In  order 
to  a  right  comprehension  of  the  subject  it  is  necessary  to 
distinguish  between  the  two  processes  embraced  by  the 
term  ossification.  There  is  first  the  formation  of  the 
osseous  tissue,  ossification  properly  so  called,  and  there 
is  also  the  formation  of  the  complete  bone,  a  true  organ, 
and  this  is  correctly  designated  osteogenesis.  As  regards 
ossification,  it  is  right  to  say  that  the  bone  is  formed  as  a 
rule  from  cartilage  and,  at  a  later  stage,  also  from  peri- 
osteum.  But  in  osteogenesis  there  is  a  further  process, 
the  formation  of  the  marrow,  called  by  the  speaker  me- 
dullification.  The  marrow  was  formerly  regarded  as  a 
sort  of  exudation  filling  up  the  medullary  canal  and  the 
spaces  in  the  spongy  portion  of  the  bone.  But  when  the 
living  bone  in  its  totality  came  to  be  studied,  it  was  re- 
cognized that  marrow  is  as  true  a  tissue  as  the  bone,  the 
cartilage,  or  the  periosteum.  We  find  three  principal 
forms  of  marrow,  the  red,  the  yellow,  and  the  gelatinous. 
These  three  forms,  however,  represent  different  condi- 
tions of  the  same  thing  ;  hence  the  marrow  is  a  change- 
able tissue  and  presents  a  striking  example  of  metaplasia. 
But  this  tissue  is  not  only  metaplastic,  it  is  also  of  meta- 
plastic origin.  The  greater  part  of  that  which  fills  up  the 
centre  of  a  fully  developed  bone  was  formerly  osseous 
tissue.  This  tissue  gives  up  its  lime-salts,  and  the  bone- 
corpuscles  become  changed  into  marrow-cells,  their  con- 
stitution is  altered  and  softened.  If  this  process  assumes 
an  excessive  character  we  call  it  osteoporosis,  and  in  a 
still  more  advanced  degree,  osteomalacia.  But  this  is 
not  the  only  mode  of  origin  of  the  marrow,  for  it  may  be 
formed  directly  from  cartilage.  This  fact  was  first  dis- 
covered by  Virchow  while  studying  the  development  of 
the  bones  forming  the  base  of  the  skull.  He  found  that 
only  a  small  portion  of  that  part  of  the  sphenoid  bone 
forming  the  clivus  Blumenbachii,  which  is  cartilaginous 
at  birth,  undergoes  direct  ossification.  The  greater 
portion  is  transformed  directly  into  marrow.  It  was  here 
also  that  the  author  was  enabled  to  follow  the  process  of 
metaplasia  of  the  small,  red  marrow-cells  into  large  fat- 
cells,  the  change  of  red  into  yellow  marrow.  The  tran- 
sition of  cartilage  into  marrow-cells  occurs  in  the  same 
way  as  does  that  of  bone  into  marrow,  with  this  differ- 
ence, however,  that,  while  the  marrow  from  osseous  tissue 
is  permanent,  the  same  substance  formed  from  cartilage 
shows  a  marked  tendency  to  ossification.  So  striking  is 
this  tendency,  indeed,  that  perhaps  the  majority  of  ob- 
servers regard  ossification  from  cartilage  as  a  secondary 
act,  the  first  part  of  the  process  being  a  meduUification. 
This  is  not  always  the  case,  however,  for  an  examination 
of  lateral  sections  of  the  epiphyseal  cartilage  in  normal 
osteogenesis  shows  beyond  question  that  the  process  here 
consists  in  a  direct  ossification  of  the  cartilaginous  tissue. 
The  development  of  bone  is  thus  shown  to  furnish  a 
striking  example  of  a  manifold  metaplasia.  How  little 
the  simple  nutritive  standpoint  serves  to  explain  this 
metaplasia  is  well  shown  by  the  results  of  the  studies 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


295 


made  of  the  formation  of  the  spongy  tissue  dtring  the 
last  decade.     These  have  shown  that  the  number  and 
the  direction  of  the  bony  trabeculae  depend  upon  the 
pressure  and  traction  forces  working  from  without.     The 
spongy  tissue  arises  from  a  formation,  not  of  the  osseous 
trabeculae,  but  of  marrow  which  dissolves  out  the  bone 
by  a  process  of  metaplasia  in  some  places  and,  so  to 
speak,  spares  it  in  others.     The  main  part  of  the  process 
consists  in  a  medullification  rather  than  in  an  ossifica- 
tion.   These  examples  must  have  the  effect  of  directing 
more  attention  than  was  formerly  given  to  the  meta< 
plastic  character  of  many  processes,  the  exact  signifi- 
cance of  which  can  only  be  grasped  by  regarding  them 
in  this  light.     Without^such  an  explanation,  indeed,  the 
etiology  of  these  various  processes  may  be  understood 
in  a  general  way,  but  beyond  this  we  could  not  go.     It 
is  very  important,  for  example,  to  know  that  syphilis 
may  cause  sclerosis  of  the  long  bones  and  also  osteopor- 
osis, but  it  is  of  still  greater  moment  to  recognize  the 
&ct  that  these  two  conditions  may  be  but  different  stages 
of  the  same  process. 

These  various  metaplasias  in  osseous  tissue  are  by  no 
means  of  equal  significance,  and  even  the  same  form  of 
metaplasia  must  be  judged  differently  under  differing 
circumstances.  The  secondary  formation  of  marrow 
from  compact  bone  substance  forms  in  normal  develop- 
ment the  final  stage  of  osteogenesis,  and  we  may  thus 
legArd  it  as  a  progressive  process.  But  in  osteomalacia, 
on  the  other  hand,  in  which  medullification  surpasses  the 
normal  limits,  we  derive  the  impression  of  a  destructive 
and  regressive  process.  Wherefore  it  follows  that  a 
prognostic  judgment  upon  these  metaplastic  changes 
cannot  be  based  upon  a  simple  knowledge  of  these  pro- 
cesses, but  must  rest  upon  a  consideration  of  all  the 
circumstances  in  which  the  organ  is  placed. 

Professor  Virchow  then  discussed  the  metaplasia  of 
appose  tissue.  The  changes  here  are  rather  monoto- 
nous in  character,  the  fatty  being  metamorphosed  most 
frequently  into  mucous  tissue,  but  the  study  of  them  is 
not  without  interest  as  bearing  upon  the  formation  of 
some  forms  of  tumor.  In  this  kind  of  metaplasia  the  fat 
is  removed  from  the  cells,  but  the  ceils  remain  and 
generate  mucus.  This,  however,  is  not  distinct  from 
the  cells ;  it  is  not,  strictly  speaking,  secreted,  but  re- 
mains as  an  integral  part  of  the  tissue.  The  process  is 
a  return  of  the  fatty  tissue  to  the  same  tissue  from  which 
it  is  formed  in  embryonic  development.  It  is  not 
emaciation,  for  there  is  evidently  a  difference  between 
simple  atrophy  of  fatty  tissue  and  the  formation  of  mu- 
cous tissue  by  metaplasia.  A  lipoma  may  arise  from 
adipose  tissue  by  partial  hyperplasia.  Sometimes  lipo- 
mata  present  numerous  points  of  gelatinous  formation, 
and  there  are  even  tumors  growing  from  adipose  tissue 
which  are  gelatinous  throughout  their  whole  extent. 
These  tumors  are  called  by  Virchow  myxomata.  Since 
mucous  tissue  is  normally  embryonal,  one  might  say  in 
a  certain  sense  that  myxomata  are  composed  of  em- 
bryonic tissue ;  indeed  that  tumor,  called  by  the  author 
myxoma  of  the  villi  of  the  chorion,  the  hydatidiform 
mole,  is  wholly  embryonal.  But  every  myxoma  is  not  of 
congenital  origin,  for  besides  the  primary  embryonal 
mucous  tissue  there  is,  as  we  have  seen,  a  secondary 
tissue  of  this  kind  formed  in  adults  by  metaplasia,  and 


from  which  myxomata  are  developed  by  hyperplasia. 
The  author  then  spoke  of  tumors  formed  from  naevi 
which  may  be  said  to  be  embryonal  tissue,  and  of 
enchondromata  arising  from  little  islets  of  cartilage  for- 
gotten in  the  process  of  ossification,  which  are  certainly 
of  non-congenital  origin.  And  he  took  occasion  here  to 
refute  the  theory  of  Cohnheim,  who  regards  all  tumors 
as  originating  from  unchanged  embryonic  tissue. 

Hitherto  the  argument  had  been  confined  to  meta- 
plasia between  tissues  of  a  similar  character,  but  in  con- 
cluding the  author  touched  briefly  upon  that  occurring 
in  tissues  belonging  to  different  categories.  He  had 
never  seen  an  instance  of  the  formation  of  connective 
tissue  from  epithelial  elements,  but  was  convinced  that 
the  converse  does  obtain.  He  did  not  believe,  as  is 
maintained  by  some,  that  the  white  blood-corpuscles 
were  capable  of  producing  every  form  of  new  tissue,  or, 
in  other  words,  that  they  were  possessed  of  the  property 
of  absolute  metaplasia,  but  thought  that  their  powers  in 
this  respect  were  limited. 

Of  course,  so  difficult  a  problem  as  the  possibility  of 
metaplasia  in  the  sense  of  dissimilar  tissue  production 
cannot  be  regarded  as  solved  because  affirmed  by  even 
so  high  an  authority  as  Professor  Virchow.  Indeed,  the 
learned  speaker  himself  disclaimed  any  such  assumption, 
and  expressed  simply  his  gratification  that  he  had  been 
instrumental  in  directing  the  attention  of  investigators  to 
this  point,  and  he  hoped  that  their  labors  would  be 
simplified  somewhat  at  the  start  by  an  acquaintance 
with  the  less  complicated  forms  of  metaplasia  which  they 
had  just  been  considering. 


WHAT  IS   THE   CHOLERA   MICROBE? 

The  nomenclature  of  bacteriology,  as  is  always  the  case 
in  every  new  science,  is  by  no  means  satisfactory.  The 
discoverer  of  each  new  form  of  micro-organic  life  ha& 
given  it  whatever  name  best  suited  his  frincy,  and  while 
this  was  doubtless  satisfactory  to  the  word*coiner,  it  re- 
salted  in  a  confusion  of  terms  sufficient  to  appal  even 
the  most  stout-hearted  tyro  in  bacterial  studies.  Cohn 
has  done  much  by  his  dassification  to  simplify  the  ques* 
tion,  and  although  his  system  is  by  no  means  perfect,  it 
has  been  adopted  by  most  of  the  German  writers,  Koch 
among  the  rest.  Yet  the  latter  seems  to  have  departed 
from  this  nomenclature  in  one  notable  instance  at  least, 
in  the  designation,  namely,  of  the  supposed  cholera  mi* 
crobe.  He  has  called  it  the  comma-bacillus.  The  qual* 
ifying  word  ''comma"  was  not  happily  chosen,  for  it 
suggests  an  organism  of  curved  form  with  a  head  and  a 
tapering  extremity,  whereas  the  cholera  microbe  is  of 
equal  size  throughout  with  no  distinction  of  its  extrem- 
ities. But  more  than  this,  as  Koch  himself  says,  the 
^*  bacillus ''  is  probably  not  a  bacillus  at  all,  but  rather  a 
spirillum.  Indeed,  there  are  many  points  of  close  re- 
semblance between  the  spirilla  and  the  microorganisms 
found  in  the  dejections  of  cholera  patients. 

Dr.  Muhlh&user,  of  Speier,  has  recently  made  a  study 
of  spirilla,  embodying  his  results  in  an  interesting  article 
appearing  in  Vtrchott/s  Archiv^  No.  i,  1884.  This  or- 
ganism he  describes  as  existing  in  the  form  of  a  long,  fine 
thread,  twisted  into  a  number  of  spiral  turns.  The  spi- 
rals are  of  equal  size  and  may  vary  in  number  from  two 


296 


THE  MEDICAL  RECORD. 


[September  13,  1884, 


to  ten  or  more.  There  is  no  appearance  of  head  or  tail, 
each  end  of  the  spiral  thread  being  of  equal  thickness. 
These  bodies  are  possessed  of  the  power  of  independent 
motion^  turning  upon  themselves  like  the  screw  of  a  pro- 
peller. The  spirillum  seems  to  be  enclosed  in  a  sheath, 
like  the  aids  cylinder,  which  terminates  at  each  extrem- 
ity in  a  cilia4ike  prolongation.  It  is  probably  to  these 
cilia  that  the  body  owes  its  power  of  motion.  The  spi- 
rilla grow  by  direct  increase  in  length,  adding  coil  upon 
coil  until  the  number  may  reach  a  dozen  or  more.  The 
larger  the  number  of  spirals  the  slower  is  the  motion. 

Spirilla  are  reproduced  by  fission,  and  never  by  the 
production  of  spores.  And  here  begins  the  likeness  be- 
tween them  and  the  so-called  comma-bacilli.  The  latter, 
Koch  insists,  are  never  reproduced  by  spores,  the  parent 
microbe  must  be  present  and  alive,  otherwise  no  repro- 
duction of  organisms  can  occur.  Another  point  of 
resemblance  Hes  in  the  weak  powers  of  resistance  pos- 
sessed by  these  organisms.  Koch  says  that  drying  kills 
the  cholera  microbe  with  absolute  certainty,  and  Miihl- 
hauser  says  the  same  of  the  spirillum.  The  latter  is  even 
killed  by  sunlight,  but  seems  not  to  be  injuriously  affected 
by  cold,  and  this  fact  is  also  affirmed  of  the  cholera 
germ,  which  has  been  seen  to  revive  even  after  having 
been  frozen.  Both  these  forms  of  micro-organisms  de- 
pend upon  oxygen  for  their  existence,  a  peculiarity 
which  separates  them  sharply  from  many  other  forms  of 
bacterial  life.  Muhlhauser  saw  in  some  fresh  culture- 
fluids  certain  minute  shapes  which  seemed  to  be  straight 
and  resembled  the  bacterium  termo,  but  which  he  found 
on  closer  inspection  to  be  bent,  and  to  be  spirilla  of  but 
two  coils,  thus  resembling  also  in  form  the  cholera  germ. 
Another  peculiarity  of  the  spirilla  was  that  they  were 
sometimes  joined  together,  end  to  end,  like  links  of  a 
chain.  Koch  also  saw  this  union  in  the  case  of  the 
cholera  microbes,  two  being  joined  in  the  shape  of  an  S, 
or  at  times  there  were  longer  strings,  looking  like  the 
spirals  of  a  corkscrew.  Of  course,  in  this  case  the 
resemblance  is  only  in  outward  form  and  may  be  ap- 
parent only,  but  the  other  points — the  absence  of  spores, 
the  slight  power  of  resistance  to  outward  influences,  cold 
alone  excepted,  and  their  dependence  upon  oxygen  for 
existence — would  indicate  a  near  relationship,  even 
though  they  may  not  be  members  of  the  same  family. 


THYMOL  IN  THE  TREATMENT  OF  CHOLERA. 

Professor  Bozzolo  has  written  a  letter  to  the  public 
press  in  Italy,  advocating  thymol  on  theoretical  grounds 
as  a  remedy  for  cholera.  If  it  be  true,  he  says,  that 
cholera  is  due  to  the  presence  of  micro-organisms  in  the 
intestinal  canal ;  that  these  organisms  are  developed  in 
this  part  because  they  find  there  an  alkaline  fluid  favor- 
able to  their  growth  ;  and  that  acids  kill  them,  or  at  least 
hmder  their  further  development,  then  the  problem  is  to 
find  a  slightly  soluble  acid,  and  strongly  antiseptic  sub- 
stance which  is,  in  large  quantities,  innocuous  to  the 
human  organism,  and  which  will  pass  into  the  intestines 
without  sufiering  appreciable  change  in  the  stomach. 
These  valuable  properties,  the  learned  professor  main- 
tains, are  possessed  by  thymol.  This]  substance^  may  be 
given,  he  says,  without  danger,  in  the  dose  ^  of  three 
•drachms  a  day,  divided  in  capsules  containing^seven  and 


a  half  grajps  each.  Judging  from  the  recent  telegraphic 
reports  of  the  ravages  of  the  cholera  in  Italy,  we  are 
forced  to  conclude  either  that  this  remedy  has  not  been 
tried  to  any  great  extent,  or  else  that  it  has  been  proven 
ineffectuaL 

THE  PREVALENCE  OF  TYPHOID  FEVER  IN  NEW  YORK. 

Some  statements  have  been  made  in  the  daily  press  to 
the  efiect  that  typhoid  fever  is  prevailing  more  than  usu- 
ally m  this  city.  Such  is  not  the  case,  however,  accord- 
ing to  the  latest  reports.  There  is  always  some  increase 
in  the  disease  in  the  fall,  and  the  mortality  statistics  show 
that  the  deaths  therefrom  are  one-third  greater  in  the 
last  quarter  of  the  year  than  in  the  first  During  the 
past  month  of  August  the  number  of  cases  has  been 
from  24  to  34  per  week,  and  in  the  first  week  of  Septem- 
ber  the  number  reported  was  48. 

The  total  number  of  cases  in  August  was  140,  while  a 
year  ago  the  number  in  the  same  month  was  344.  In 
September,  1883,  the  cases  reached  a  total  of  303  for 
the  month,  or  76  per  week.  So  that  typhoid  fever  now 
prevails  a  little  more  than  in  1882,  but  it  is  much  less 
than  in  1883. 

At  the  present  time,  with  so  many  persons  returning 
from  the  country,  a  certain  proportion  of  the  cases  axe 
probably  imported.  Then  the  settling  again  in  a  house 
whose  drains  and  pipes  have  not  been  flushed  for  some  time 
is  a  thing  not  always  without  danger.  A  timely  caution 
from  the  family  physician  at  present  might  be  of  much 
service. 

THE   BAD   SANITARY   CONDITIONS    OF    THE  GREELY 
PARTY  WHILE  AT  CAPE  SABINE. 

According  to  Dr.  Green's  report  of  the  medical  history 
of  the  survivors  of  the  Lady  Franklin  expedition,  pub- 
lished in  last  week's  Record,  it  seems  that  this  party 
spent  their  long  winter  night  in  a  miserable  hovel  25 
feet  long  by  17  feet  wide  and  4  feet  high,  making  the 
cubic  air  space  1,700  feet.  In  this  the  twenty-four 
members  of  the  party  lived  all  winter,  having  a  cubic 
air  allowance  of  about  seventy  feet  for  each  man.  "The 
whole  party,"  it  is  said,  ''  could  barely  squeeze  in  and  lie 
at  length,  two  or  three  being  obliged  to  occupy  the  same 
sleeping  bag."  There  were,  it  appears,  certain  vent- 
holes  in  the  roof,  which  were  sometimes  stuffed  with 
rags,  and  on  one  occasion  the  whole  company  came  near 
perishing  of  asphyxia  by  the  carbonic  acid  from  an 
alcohol  lamp  which  was  burning  in  the  hut  while  the 
vent-holes  were  stopped.  Doubtless  the  sufferings  and 
mortality  of  the  party  were  augmented  by  the  evil  effects 
of  bad  air.  It  is  well  known  that  between  four  and  five 
hundred  cubic  feet  of  air  pass  through  the  lungs  daily, 
and  in  the  same  period  about  twenty-three  cubic  feet  of 
oxygen  are  absorbed,  and  that  the  size  of  an  apartment 
in  which  persons  are  confined  should  be  such,  that 
there  shall  not  be  less  than  eight  hundred  cubic  feet 
for  each  person  occupying  the  room.  A  multitude 
of  instances  illustrative  of  the  fatal  effects  of  neglect 
of  this  precaution  are  on  record,  the  most  notable  of 
which  is  that  of  the  "  Black  Hole  of  Calcutta,"  an  ac- 
count of  which  may  be  found  in  any  text-book  on  phy- 
siology. The  baneful  results  of  imperfect  haematosis 
'rom  bad  ventilation  are  familiar  to  all  medical  readers, 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


297 


and  it  would  appear,  by  analyzing  the  morbid  phenomena 
presented  by  various  members  of  the  expedition,  and  so 
well  described  by  Dr.  Green,  that  the  party  when  found 
were  suffering  almost  as  much  from  want  of  oxygen,  and 
from  accumulation  of  carbonic  acid  in  their  systems,  as 
from  deprivation  of  food.  Add  to  this  that  they  had 
long  ceased  to  bathe  themselves  or  take  regular  exercise 
(except  perhaps  Long  and  Brainard,  who  were  the  most 
healthy  of  the  lot),  and  that  they  were  extricated  from 
appalling  filth,  and  the  wonder  is  that  there  were  any 
survivors  to  tell  the  story. 


MENSTRUATION  INiWOMEN  AND  IN  ANIMALS. 

A  Harvard  medical  student,  in  the  Boston  Medical  and 
Surgical  Journal^  Kvigast  28,  1884,  has  an  interesting 
article  on  the  phenomenon  of  menstruation  in  women 
and  of  heat  in  animab.  According  to  this  writer, 
**  woman  is  more  different  from  the  man  {sic)  than  the 
brute  females  are  from  their  males,  and  the  reproductive 
processes  are  intensified  in  her.*'  In  woman  the  men- 
strual period  *'  is  the  period  of  absent  sexual  desire,  and 
is  by  no  means  contemporaneous  with  ovulation.''  ''  The 
human  intelligence  has  rendered  woman  sexually  inde- 
pendent of  the  heat ;  sexual  congress  is  permitted  at  any 
time,  and  therefore  she  is  subject  to  a  condition  not 
prevalent  in  the  brute  animals  ;  she  is  liable  to  conceive 
at  any  time."  This  writer  goes  on  to  observe  that,  in 
view  of  the  possibility  of  pregnancy  at  any  time,  and  the 
immediate  demands  upon  her  nutritive  force  which  would 
come  from  such  an  event,  '*  woman  has  to  be  run  at  a 
higher  pressure  (sic)  than  is  necessary  for  the  needs  of 
the  non-pregnant  female."  This  lucid  explanation  is 
supplemented  further  on  by  the  statement  that,  since  the 
human  female  "  is  run  at  such  high  pressure,  frequent 
overflows  of  nutritive  material  are  necessary  in  the  non- 
pregnant women,  and  these  overflows  taJce  place  at 
certain  periods  of  genital  hyperaemia  inherited  from  the 
lower  animals,  that  is,  at  the  menses.  That  is  to  say,  the 
reproductive  side  of  menstruation  is  emphasized  in 
woman,  the  sexual  side  in  brutes." 

Despite  certain  infelicities  of  style,  the  present  status 
of  the  subject  is  fairly  represented  in  the  article.  The 
ovulation  theory  is  no  longer  tenable,  as  cases  are  on 
recoil  of  menstruation  after  double  ovariotomy,  of  ovula- 
tion without  menstruation,  and  of  menstruation  without 
ovulation.  Instances  of  conception  fifteen  days  or  more 
after  coitus  are  numerous.  Stedman  has  reported  a  case 
where  "  a  woman  had  menstruated  regularly  to  the  time 
of  her  death,  but  whose  ovaries  were  found  cystic  and 
atrophied."  It  would  seem  then  that  there  is  very  strong 
evidence  against  the  ovaries  being  the  source  of  the 
menstrual  impulse,  and  the  writer  asks  whether  this  im- 
pulse may  not  come  from  the  general  system.  He  points 
out  the  fact  that  fear,  horror,  and  violent  emotions,  in 
general,  are  known  to  have  an  immediate  effect  on  men- 
struation in  many  cases.  ^\  The  influence  of  the  mammae 
is  marked.  Dr.  Campbell  cites  two  cases  of  premature 
menstruation  in  children  caused  by  mammary  inflamma- 
tion." Change  of  climate  often  suppresses  menstruation ; 
a  sea-voyage  often  delays  or  hastens  the  next  period ; 
anaemia  is  a  most  fruitful  cause  of  amenorrhoea,  and  so, 
alienists  have  told  us,  is  a  mental  disease.     The  writer 


takes  up  the  recent,  theory  propounded  by  Kindrat  and 
Williams,  and  defended  by  Dr.  Chadwick  in  a  former 
number  of  the  North  American  Review ^  that  ''menstru- 
ation is  neither  a  congestion  nor  a  species  of  erection,  but 
a  molecular  disintegration  of  the  mucous  membrane  of 
the  uterus,  followed  by  hemorrhage/'  In  other  words, 
the  uterine  mucus  undergoes  disintegration  and  exfol- 
iates with  each  menstrual  period ;  menstruation  is  then 
a  sort  of  disappointed  pregnancy.  ''  When  conception 
takes  place  a  process  of  nine  months  or  more  of  uterine 
increase  is  gone  through,  followed  by  fatty  degeneration 
and  desquamation  in  the  puerperal  state.  When  no  con- 
ception, the  process  is  completed  in  a  little  over  a  week." 
The  observations  of  Moricke  and  Wyder  seem  to  dis- 
prove this  view ;  Moricke  showed,  by  scraping  with  a 
curette  the  uterine  mucous  membrane  of  his  menstruat- 
ing patients,  that  tliere  was  no  destruction,  partial  or  total, 
of  the  mucous  membrane,  and  no  fatty  degeneration ; 
the  bleeding,  according  to  him,  is  due  to  diapedesis. 
Wyder,  by  a  series  of  careful  observations  also  arrived  at 
the  same  conclusion,  that  in  menstruation  there  is  no 
denudation  of  the  mucous  membrane. 

With  respect  to  theories  of  menstniation  this  writer 
thinks  that  we  are  more  badly  off  than  we  were  ten  years 
ago,  when  this  physiological  phenomenon  was  better  ex- 
plained than  it  can  be  to-day,  in  the  light  of  all  the  facts. 

^ewB  tit  tlije  "^SeSUt^. 

Dr.  Van  der  Veer,  of  Albany,  gave  a  reception  at 
his  home  in  honor  of  Mr.  Lawson  Tait,  of  London. 

In  Memory  of  Civiale. — ^The  municipal  council  of 
Paris  has  voted  to  give  the  name  of  Civiale  to  one  of  the 
streets  in  Paris. 

A  New  Emergency  Hospital  for  Bellevue  is  soon 
to  be  established  in  one  of  the  down-town  districts.  This 
will  relieve  some  of  the  work  of  the  Chambers  Street 
Hospital 

Paris  is  to  Have  a  Baby  Show. — Artists  and  doc- 
tors are  to  be  on  the  committee  of  judges,  and  healthful- 
ness  is  to  be  considered  as  well  as  beauty  in  giving  the 
awards. 

Claimants  to  Priority  in  the  Discovery  of  the 
Cholera  Bacillus. — ^The  number  of  these  is  increasmg 
weekly.  Besides  the  names  of  \^t.  !Mstowe  and  Pro- 
fessor Pacini,  a  Polish  paper  now  claims  the  honor  for 
Dr.  KlodzianowskL  The  Lancet  now  brings  up  Dr.  A. 
H.  Hassall,  who  claims  to  have  discovered  the  bacillus 
thirty  years  ago. 

The  Next  International  Medical  Congress. — 
Referring  to  its  next  place  of  meeting  the  British  Medi- 
ccU  Journal  says  :  "  We  may  be  sure  that  our  transatlan- 
tic cousins  will  leave  nothing  undone  to  make  the  next 
meeting  as  successful  as  the  last  two,  if  indeed  they  do 
not  succeed  in  eclipsing  former  achievements ;  however 
this  may  be,  the  announcement  will  be  received  with 
great  pleasure  in  this  country,  where  we  have  learned  to 
set  a  high  value  on  the  work  done  by  the  medical  profes- 
sion in  the  United  States." 

Medical  Changes  in  Berlin. — Owing  in  part  to 
the  appointment  of  Professor  Schweninger  as  a  member 


298 


THE  MEDICAL  RECORD. 


[September  13,  igg^ 


of  the  Imperial  Board  of  Health,  the  Director,  Dr. 
Struck,  has  resigned.  Dr.  Koch  has  refused  to  be  his 
successor,  and  has  also  withdrawn  from  the  Board,  being 
content  with  his  position  as  Professor  of  Hygiene  and 
Director  of  the  Hygienic  Institute.  Dr.  Julius  Wolf  has 
been  made  Extraordinary  Professor  of  Surgery,  and  Dr. 
Mendel  Extraordinary  Professor  of  Psychiatry. 

Ozone  and  Cholera. — During  the  cholera  epidemic 
at  Marseilles,  ozone  disappeared  from  the  atmosphere. 
When  it  reappeared,  after  a  southwest  wind,  the  cholera 
mortality  fell.  It  is  not  easy  to  produce  ozone ;  there 
are  many  methods  recommended,  but  they  are  all  mostly 
worthless.  M.  Onimus  only  admits  one  method,  electri- 
fying the  oxygen  of  the  air  either  by  a  Ruhmkorft*s  induc- 
tion machine  and  Berthelot's  tubes,  or  by  an  ordinary 
electric  machine  ;  at  the  Pharo  hospital  M.  Onimus 
adopted  the  latter  method.  The  ozonoscopic  papers 
testified  that  ozone  was  produced.  Its  actual  therapeutic 
properties  could  not  be  determined,  as  the  usual  treat- 
ment was  observed  conjointly.  The  mortality  was  low 
in  those  wards  where  ozone  was  artificially  produced. 

The  Elevation  of  a  Quack. — It  appears  that  Berlin 
medical  circles  are  much  disturbed  over  the  elevation  of 
Dr.  Schweninger,  Bismarck's  Leibarzt,  to  a  position  in  the 
Medical  Faculty  of  the  Berlin  University.  Schweninger 
had  no  scientific  or  even  social  standing  amongst  the 
profession  previous  to  his  success  with  Bismarck,  and  the 
correspondent  of  the  AUgemeiner  Wiener  Meditinische 
Zeitung  affirms  that  if  he  presented  himself  for  admission 
to  the  Berlin  Medical  Society  now  he  would  be  undoubt- 
edly rejected. 

Schweninger  was  formerly  connected  with  the  Munich 
Faculty,  but  was  obliged  to  leave  somewhat  under  a 
cloud.  He  is  claimed  to  have  advertised  and  applied  a 
so-called  "  Schweninger-cure "  for  obesity,  fatty  heart, 
etc.  This  "  cure/'  which  he  applied  to  Bismarck,  is  sub- 
stantially that  laid  down  by  Professor  Oertel  in  "  Ziem- 
ssen's  Handbuch  der  Therapie  der  Kreislaufstdrungen, 
Feltherz,'*  etc. 

Despite  the  unpleasant  pushing  forward  of  the  obnox- 
ious quack,  the  Berlin  medical  journals  are  forced  to  keep 
very  quiet,  and  it  is  only  through  Berlin  correspondence 
that  the  true  state  of  feeling  is  made  known. 

Death  of  Professor  J.  Cohnheim. — We  regret  to 
learn  of  the  death  of  Professor  J.  Cohnheim,  at  the  com- 
paratively early  age  of  forty-six.  He  died  of  gout  com- 
plicated with  some  renal  trouble.  Professor  Cohnheim 
was  one  of  the  most  distinguished  of  the  pupils  of  Vir- 
chow,  whose  assistant,  in  the  Berlin  Pathological  Insti- 
tute, he  was  from  1864  to  1868.  In  1868  he  was  ap- 
pointed ordinary  Professor  of  Pathology  at  Kiel,  and,  in 
1872  he  preceded  Waldeyer  in  a  similar  capacity  at 
Breslau.  It  was  there  that  he  made  his  well-known  re- 
searches on  the  changes  produced  by  embolism,  and  on 
the  escape  of  the  white  blood-corpuscles  through  the 
walls  of  the  vessels  in  inflammation.  In  1876  he  suc- 
ceeded Wagner  in  the  chair  of  General  Pathology  and 
Pathological  Anatomy  in  the  University  of  Leipsic,  and 
held  that  professorship  up  to  the  time  of  his  death. 

The  AcADfiMiE  de  Medecine  of  Paris  continues  its 
session  through  the  summer.  At  its  meeting  on  August 
19th,  the  subject  of  cholera  was  discussed.     M.  Bouley 


read  a  paper  for  M.  Chauveau  on  gangrenous  septicaemia, 
in  which  it  was  shown  that  gangrenous  septicaemia  in 
man  is  identical  with  that  in  animals,  and  depends  upon 
a  microbe  a&obie^  which  is  probably  only  the  septic  vibrio 
of  Pasteur. 

A  Place  for  Cholera  to  Locate. — One-fourth  of 
the  whole  population  of  the  State  of  New  Jersey  drink 
the  water  of  the  Passaic  River,  taken  from  a  point  where 
the  tide,  laden  with  the  sewage  of  Newark's  140,000  peo- 
ple, flows  up  and  meets  the  downward  current  bearing 
the  sewage  and  factory  refuse  of  60,000  dwellers  in  Pat- 
erson  and  other  cities  on  its  banks  a  few  miles  above. 
The  city  of  Passaic  now  proposes,  says  the  Sanitary  En- 
gineer^ to  add  its  quota  of  sewage  to  the  river  by  estab- 
lishing a  system  of  drainage.  The  water  of  the  Passaic 
has  been  condemned  as  dangerous  long  ago.  But  in 
view  of  a  prospective  visit  of  cholera  the  matter  becomes 
really  serious  and  of  interest. to  others  than  those  living 
by  the  polluted  river.  The  establishment  of  pumping 
works  on  the  Passaic  above  all  source  of  pollution  is  the 
remedial  measure  urged  by  our  contemporary,  and  it  is 
one  that  has  been  approved  of  by  competent  engineers. 

Alleged  Successful  Inoculatiok  of  Lower  Ani- 
mals WITH  Cholera. — A  cablegram  from  London  says 
that  Drs.  Reitsch  and  Ricati,  of  Marseilles,  claim  to  have 
successfully  inoculated  lower  animals  with  the  cholera 
microbe.  The  animals  died  with  choleraic  symptoms. 
Remembering  the  great  ease  with  which  septic  pheno- 
mena can  be  produced  in  certain  lower  animals,  the 
reports  of  successful  inoculations  must  be  received  with 
skepticism  until  full  details  are  given. 

The  Paradise  of  Eclectics. — A  writer  in  the  Kan- 
sas Medical  Journal  grows  enthusiastic  over  the  present 
and  future  of  Eclecticism  in  Kansas.  The  Eclectics  in  » 
that  State  number  nearly  six  hundred.  "  They  do  not," 
he  says,  '^  seek  seclusion  in  rural  districts  generally,  but 
occupy  lucrative  positions  in  cities  and  country  towns, 
and  in  comparison  with  other  industrial  classes  they  are 
thrifty,  diligent,  have  nice  homes,  pretty  wives,  sons, 
and  daughters  (so  we  think),  wear  good  clothes,  drive 
fine  horses,  own  miles  of  prairie,  bank  stocks,  meet  the 
difficulties  and  enjoy  the  incidents  that  go  to  make  up  a 
busy,  active  life."  The  State  Society  has  obtained  a 
charter  for  a  medical  college.  ^ 

The  Canada*  Medical  Association. — We  learn 
from  a  correspondent  that  the  annual  meeting  of  this 
Association  at  Montreal,  just  previous  to  the  meeting  of 
the  British  Association,  was  unusually  well  attended  and 
successful.  We  have  received,  too  late  for  publication, 
the  address  of  the  president,|Dr.  M.  Sullivan,  of  Kingston. 
It  was  a  most  able  e£fort,  and  contained  a  great  deal  of 
solid  statistical  matter,  as  well  as  of  practical  suggestion 
regarding  the  medical  afifairs  of  Canada. 

The  Cholera. — ^The  cholera  has  attacked  Naples 
with  a  severity  far  surpassing  that  with  which  it  visited 
Marseilles,  or  even  Toulon.  On  September  8th  diere 
were  eight  hundred  fresh  cases  and  three  hundred  deaths 
within  twenty-four  hours.  Some  sixteen  provinces  of 
Italy  have  now  been  attacked.  In  most  of  these,  how- 
ever, the  daily  number  of  firesh  cases  is  not  large,  varying 
from  one  or  two  to  fifteen  or  thirty.  The  disease  is 
spreading  slowly  in  Spain,  but  is  evidently  dying  out  at 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


299 


Toulon  and  Marseilles.  The  total  number  of  deaths 
from  cholera  up  to  date  is  about  six  thousand,  which 
means  that  there  have,  since  June,  been  from  twelve 
thousand  to  fifteen  thousand  cases  of  the  disease. 

Reviews  and  Notices. 

Practical  Manual  of  Diseases  of  Women  and  Uter- 
ine Therapeutics,  for  Students  and  Practitioners. 
By  H.  Macnaughton  Jones,  M.D.,  M.C.H.,  F.R.C.S. 
I.  and  E.  Examiner  in  Obstetrics  Royal  University  of 
Ireland,  Fellow  of  the  Academy  of  Medicine  in  Ire- 
land, etc.  New  York :  D.  Appleton  &  Co.  1884. 
i2ino.  pp.  392. 

It  is  seldom  that  we  see  a  book  so  completely  fill  its 
avowed  mission  as  does  the  one  before  us.  It  is  practi- 
ce from  beginning  to  end,  and  cannot  fail  to  be  appre- 
ciated by  the  readers  for  whom  it  is  intended.  The 
author's  style  is  terse  and  perspicuous,  and  he  has  the 
enviable  faculty  of  giving  the  learner  a  clear  insight  of 
his  methods  and  reasons  for  treatment.  Prepared  for  the 
practitioner,  this  little  work  deals  only  with  his  every- day 
wants  in  ordinary  family  practice.  Every  one  is  com- 
pelled to  treat  uterine  disease  who  does  any  general  busi- 
ness whatever,  and  sjiould  become  acquainted  with  the 
minor  operations  thereto  pertaining.  The  book  before 
as  covers  this  ground  completely,  and  we  have  nothing 
to  offer  in  the  way  of  criticism.  The  illustrations  of  dis- 
eased conditions  and  of  instruments  are  numerous  and 
appropriate. 

Diphtheria,  Croup,  Etc.  ;  or.  The  Membranous  Dis- 
eases :  Their  Nature,  History,  Causes,  and  Treat- 
ment ;  with  a  Review  of  the  Prevailing  Theories  and 
Practice  of  the  Medical  Profession  ;  also  a  Delineation 
of  the  New  Chloral  Hydrate  Method  of  Treating  the 
Same,  its  Superior  Success,  and  its  Title  to  be  con- 
sidered a  Specific.  By  C.  B.  Galentin,  M.D.  Cleve- 
land, O.:  Printed  at  the  Publishing  House  of  the 
Evangelical  Association.     1884. 

The  title  of  this  book  sufficiently  indicates  the  object  of 
the  writer  in  giving  it  to  the  world.  The  author  states 
that  since  1875,  when  he  first  began  to  use  chloral  in 
the  treatment  of  diphtheria,  he  has  given  it  in  over  five 
hundred  well-marked  cases  of  the  disease,  with  a  mor- 
tality of  less  than  two  per  cent.  Prior  to  that  time,  when 
employing  the  ordinary  treatment,  he  had  encountered  a 
mortality  of  from  25  to  33^  per  cent.  The  chloral  is 
^ven  in  small  repeated  doses  with  the  object  of  induc^ 
rng  and  maintaining  a  quiet  somnolent  state.  A  mod- 
erate Jbypnotic  effect  is,  in  the  author's  experience,  es- 
sential to  the  best  results,  as  at  this  point  the  temperature 
and  pulse-rate  are  reduced,  and  worry,  headadie,  and 
nausea  disappe&r.  This  effect  i^  also,  he  states,  an  indi- 
cation that  the  remedy  has  been  absorbed  into  the  blood 
in  sufficient  quantity  to  produce  upon  it  specific  effects. 

A  Treatise  on  Ophthalmology  for  the  General 
Practitioner.  Illustrated.  By  Adolf  Alt,  M.D. 
Chicago,  St  Louis,  &  Atlanta:  J.  H.  Chambers  & 
Co.  1884. 
This  book,  as  its  title  implies,  is  intended  solely  for  the 
general  practitioner.  Its  object,  as  stated  in  the  preface, 
IS  to  give  the  general  practitioner  a  clear  idea  of  the 
principles  of  ophthalmology,  together  with  so  much  only 
of  its  practice  as  he  might  be  reasonably  justified  in  at- 
tempting With  this  aim  in  view  the  author  has  suc- 
ceeded in  producing  a  really  valuable  work,  one  which 
may  be  perused  with  profit  by  the  non-specialist,  and 
which  he  will  not  be  forced  to  lay  aside  because  over- 
burdened with  details  relating  to  subjects  of  little  or  no 
use  to  him.  The  work  contains  numerous  illustrations 
which,  though  rather  coarse  in  their  execution,  are  yet 
sufficiently  clear  to  answer  the  purpose  intended.     The 


book  is  neatly  printed  on  good  paper  and  will  be  found 
a  valuable  addition  to  the  library  of  the  general  practi- 
tioner. 

Fat  and  Blood  :  An  Essa^  on  the  Treatment  of  Cer- 
tain Forms  of  Neurasthenia  and  Hysteria.  By  S.  Weir 
Mitchell,  M.D.  Third  edition.  Philadelphia :  J.  B. 
Lippincott  &  Co.  1SS4. 
The  author  states  in  his  preface  that  he  has,  in  the  pres- 
ent edition,  rewritten  parts  of  the  book,  and  has  added 
many  practical  hints,  particularly  with  regard  to  the 
treatment  of  obesity  and  the  use  of  milk.  Dr.  Mitchell's 
method  of  treating  certain  classes  of  nervous  invalids  is 
now  well  known  and  has  received  substantial  endorse- 
ment on  both  sides  of  the  Atlantic.  For  our  part,  we 
believe  that  the  method  advocated  is  an  immense  addi- 
tion to  therapeutics,  and  one  whose  value  is  yet  not  suf- 
ficiently appreciated.  At  the  time,  we  are  quite  aware 
that  the  proper  cases  must  be  selected,  and  that  treat- 
ment must  be  conducted  with  great  care  and  judgment 
The  author  wisely  concludes  his  book  with  the  expression 
of  fear  lest  his  method  now  be  misused  or  misapplied. 

Text-Book  of  Medical  Jurisprudence  and  Toxi- 
cology. By  John  J.  Reese,  M.D.,  Professor  of  Med- 
ical Jurisprudence  and  Toxicology  in  the  University  of 
Pennsylvania,  etc.  Philadelphia :  Blakiston,  Son  & 
Co.  .  1884.  i2mo,  pp.  597. 
Professor  Reese  is  so  well  known  as  a  skilled  medical 
jurist  thac  his  authorship  of  any  work  virtually  guarantees 
the  thoroughness  and  practical  character  of  the  latter* 
And  such  is  the  case  in  the  book  before  us.  A  very  ex- 
tensive field  is  travelled  over  by  one  acquainted  with  all 
its  parts,  and  all  the  main  and  essential  landmarks  are 
plainly  pointed  out  to  the  reader.  We  might  call  these 
the  essentials  for  the  study  of  medical  jurisprudence. 
The  subject  is  skeletonized,  condensed,  and  made  thor- 
oughly up  to  the  wants  of  the  general  medical  practi- 
tioner, and  the  requirements  of  prosecuting  and  defend- 
ing attorneys.  If  any  section  deserves  more  distinction 
than  any  other  as  to  intrinsic  excellence,  it  is  that  on 
toxicology.  This  part  of  the  book  comprises  the  best 
outline  of  the  subject  in  a  given  space  that  can  be  found 
anywhere.  As  a  whole,  the  work  is  everything  it  prom- 
ises and  more,  and  considering  its  size,  condensation,  and 
practical  character,  it  is  by  far  the  most  useful  one  for 
ready  reference  that  we  have  met  with.  It  it  well  printed 
and  neatly  bound. 

Medical  German.     A  Manual  Designed  to  Aid  Physi- 
cians in  their  Intercourse  with  German  Patients  and 
in  Reading  Medical  Works  and  Publications  in  the 
German  Language.     By  Solomon   Deutsch,  A.M., 
Ph.D.    New  York  :  J.  H.  Vail  &  Co.    1884.    Pp.  336. 
The  first  division  of  this  book  contains  an  extensive  col- 
lection of  words  and  phrases  that  pertain  to  medicine  in 
all  its  branches.    The  second  division  consists  of  conver- 
sations supposed  to  be  held  with  a  sick  patient,  and  it 
seems  to  cover  every  imaginable  morbid  condition.   There 
is  a  very  complete  German-English  index  appended. 

The  book  is  designed  to  meet  the  wants  of  physicians 
who  are  learning  German,  and  who  have  to  deal  with 
German  patients.  In  this  respect  it  fills  an  unoccupied 
niche  and  will  prove  a  most  useful  publication.  It  con- 
flicts in  no  way  with  Cutter's  Medical  German  Diction- 
ary, which  contains  a  very  much  more  copious  vocabu- 
lary. The  book  is  well  printed  and  neatly  bound  in 
flexible  covers. 

The  Theory  and  Practice  of  Medicine.     By  Fred- 
erick T.  Roberts,  M.D.,  B.Sc.,  F.R.C.P.     With  11- 
lustrations.      Fifth  American  edition.     Philadelphia : 
P.  Blakiston,  Son  &  Co.     1884.     Pp*  1008. , 
This  standard  work  has  now  reached  its  fifth  edition, 
a  sufficient  endorsement  of  its  excellence  to  make  the 
reviewer  feel  that  his  task  is  a  superfluous  one.     In  the 
present  edition  the  subjects  of  diseases  of  the  nervous 
system  and  diseases  of  the  skin  have  received  especial 


300 


THE  MEDICAL  RECORD. 


[September  13,  igg^. 


attention,  and  the  chapters  bearing  thereon  have  been 
rearranged  and  to  a  large  extent  rewritten. 

Perhaps  the  most  conspicuous  of  the  valuable  features 
of  the  work  is  its  comprehensiveness,  the  very  large  field 
that  it  covers  within  the  single  volume.  If  we  were  to 
make  any  criticism  on  the  other  hand,  it  would  be  that 
too  much  is  attempted,  and  that  the  author  fails  to  possess 
what  might  be  called  the  medical  perspective.  That  is 
to  say,  he  does  not  assign  his  space  in  strict  accordance 
with  the  relative  importance  of  the  subjects.  The  book, 
as  a  whole,  is  weak  in  its  pathology. 
.  Nevertheless  it  deservedly  takes  a  high  place  among 
the  standard  treatises  on  the  practice  of  medicine. 

An  Introduction  to  Pathology  and  Morbid  An- 
atomy. By  T.  Henry  Green,  M.D.,  London.  Fifth 
American  from  the  sixth  revised  and  enlarged  English 
edition.  With  150  Engravings.  Philadelphia  :  Henry 
C.  Lea's  Son  &  Co.     1884. 

The  present  edition  of  this  standard  work  has  been  con- 
siderably revised.  The  introductory  chapter  on  cells, 
and  the  etiology  of  disease,  and  the  chapters  on  tumors, 
regenerations,  septicaemia  and  pyaemia,  and  on  vegetable 
parasites  are  entirely  the  work  of  Mr.  Stanley  Boyd* 
They  are  very  well  written  and  do  the  author  credit. 
The  chapter  on  vegetable  parasites  in  particular  is  one 
of  the  best  presentations  of  the  subject  which  we  have 
seen,  though  it  does  not  differ  ^eatly  from  that  in  Ziegler. 

The  chapters  on  tuberculosis  and  phthisis  would  bear 
rewriting  in  the  light  of  modem  mycology.  Dr.  Green's 
work  is  more  elementary  and  less  critical  than  Ziegler's. 

It  serves  all  the  better,  however,  on  this  account,  as  a 
text-book  for  students* 

Sexual  Neurasthenia.  Its  Hygiene,  Causes,  Symp- 
toms, and  Treatment,  with  a  Chapter  on  Diet  for  the 
Nervous.  By  George  M.  Beard,  A.M.,  M.D. 
[Posthumous  Manuscript]  Edited  by  A.  D.  RocIp' 
well,  A^M.,  M.D.  New  York :  E.  B.  Treat.  ^4. 
Pp.  276. 

To  those  numerous  readers  of  the  late  Dr.  Beard's  wQrk 
who  admired  the  charm  and  suggestiveness  of  his  writings 
the  present  posthumous  volume  will  be  examined  with 
great  interest  It  will  be  found  that  the  chapters  here 
given  possess  the  same  attractiveness  which  sCttached  to 
all  the  author's  writings,  and  he  who  begins  to  read  will 
be  slow  to  lay  down  the  book  before  it  is  finished  The 
first  two  chapters  comprise  an  introduction  and  a  discus- 
sion of  the  nature  and  varieties  of  neurasthenia.  In  them 
Dr.  Beard  has  stated  clearly  and  succinctly  his  peculiar 
views  regarding  the  nature  of  nervous  exhaustion  and  its 
relation  to  the  functions  of  the  body.  He  applies  here, 
also  to  functional  nervous  disturbances,  the  laws  of  evolu- 
tion and  devolution,  or  dissolution,  using  the  same  line  of 
reasoning  which  Hughlings  Jackson  employed  in  a  series 
of  lectures  delivered  in  London  last  winter. 

These  first  two  chapters  are  decidedly  the  best  in  the 
book,  and  furthermore,  are  among  the  best  pieces  of 
medical  writing  ever  produced  by  an  American  physician. 

The  remaining  chapters  contain  much  that  is  true  with 
some  that  is  incorrect  or  commonplace.  In  practically 
working  out  his  principles.  Dr.  Beard  was  sometimes 
hasty  and  superficial.  His  diet  for  the  nervous  is  too 
fanciful,  and  his  description  of  the  evolution  of  the  sexual 
sense  amounts  to  little.  His  chapter  on  sexual  hygiene 
is  excellent  and  correct,  but  he  states  what  is  generally 
known  and  generally  accepted. 

The  illustrative  cases  deserve  attention.  They  are 
many  of  them  most  curious  histories,  and  a  perusal  of 
them  will  give  some  idea  of  the  peculiar  class  of  cases 
which  the  author  attracted  to  himself. 

Though  of  a  philosophic,  and  as  many  would  say,  an 
impractical  mind,  Dr.  Beard  was  a  successful  therapeutist, 
having  great  resources  and  thorough  confidence  in  him- 
self. The  chapter  on  treatment  is  instructive,  therefore, 
but  every  physician  of  experience  will  appreciate  that  it 


was  the  man  behind  the  therapeutical  armamentarium 
which  accomplished  the  work. 

Dr.  Beard's  book  betrays  some  signs  of  incompleteness 
and  doubtless  it  would  have  been  added  to,  and  changed 
if  the  author  had  been  spared.  As  it  is,  however  it 
shows  well  both  the  faults  and  merits  of  the  author.  And 
not  the  least  among  the  latter  is  the  perfect  cleanliness 
and  absence  of  pruriency  in  the  manner  with  which  a 
delicate  subject  is  treated. 

Work  and  Worry,  from  a  Medical  Point  of  View.  By 
W.  Henry  Kesteven,  M.R.C.S.,  L.S.A.  London: 
Diprose  &  Bateman,  Lincoln's  Inn  Fields.  1884. 

This  is  a  very  pleasantly  written  and  suggestive  essay  on 
the  evil  effects  of  worry.  By  work  the  author  means 
only  that  labor  which  is  entered  upon  and  carried  through 
with  heart  and  mind  and  soul.  And  all  distasteful  and 
unpleasant  labor  he  relegates  to  the  category  of  wony. 
Accepting  such  a  definition  of  terms,  we  fear  there  are 
few  men,  however  favorably  circumstanced,  who  have 
not  to  undergo  nearly  as  much  worry  as  work  in  the 
course  of  a  day.  For  no  labor,  however  pleasant  in  the 
main,  is  throughout  and  entirely  free  from  antioyances 
and  disagreeable  interjections.  Nevertheless^  we  can  do 
much,  if  we  set  our  minds  upon  it,  to  make  almost  any 
kind  of  labor  less  unpleasant  than  it  would  otherwise  be, 
and  thus  go  far  to  convert  our  worry  into  work.  The 
little  brochure  is  quaintly  printed  and  bound,  and  cor- 
responds to  its  external  dress  to  the  style  of  the  author. 

PROFESSOR  ROBERT   E.  kOGERS,  M.D., 

PHILADBLPHIA,  PA. 

Dr.  Robert  Empie  Rogers,  a  prominent  physician  and 
a  leading  teacher  of  chemistry,  of  Philadelphia,  died 
there  on  September  6th.  He  was  bom  in  Baltiniore, 
Md.,  in  1814,  and  after  a  careful  preliminary  education 
he  studied  and  was  graduated  as  an  M.D.  from  the  Uni« 
versity  of  Pennsylvania  in  1836.  From  1S44  to  1852 
he  was  Professor  of  Chemistry  at  that  University,  and 
assisted  his  brother,  J.  B.  Rogers,  in  preparing  his  edi- 
tion of  **  Turner's  Chemistry,"  and  on  the  death  of  that 
brother  he  succeeded  him  as  Professor  of  Chemistry  in 
the  Medical  Department  of  the  University  of  Pennsyl- 
vania, In  1877  he  resigned  this  position,  and  accepted 
a  similar  one  in  the  Jenerson  Medical  College,  in  Phil- 
adelphia. He  contributed  to  the  JourncU  of  the  Frank- 
lin Institute^  took  part  with  his  brothers  in  the  geologi- 
cal surveys  of  Virginia  and  Pennsylvania,  and  edited  the 
American  reprint  of  "C.  G.  Lehman's  Physiological 
Chemistry,"  1855. 

JACOB  H.  STEWART,  M.D., 

ST.  VADLy  MINN. 

Dr.  Jacob  H.  Stewart,  a  prominent  physician  of  St 
Paul,  Minn.,  died  of  apoplexy,  August  25th,  ult,  aged 
fifty-six  years.  He  was  educated  at  the  Academy  in 
Peekskill,  N.  Y.,  where  his  father,  Dr.  Philander  H. 
Stewart,  resided ;  he  afterward  entered  Yale  College,  re- 
maining there  three  years,  and  finally  graduated  at  the 
University  Medical  College  in  185 1.  In  1855  ^^  settled 
in  St  Paul,  Minn. 

In  1 86 1,  at  the  breaking  our  of  the  war,  he  went  as 
surgeon  of  the  First  Minnesota  Regiment  While  attend- 
ing the  wounded  on  the  Bull  Run  battle-field  he  was 
taken  prisoner  and  confined  in  Richmond  jai4.  Being 
paroled,  he  returned  to  St.  Paul  and  became  examiner 
for  recruits.  He  was  elected  mayor  of  St.  Paul  in  1864 
and  again  in  1869,  1871,  and  1873.  ^^  ^^7^  ^^  ^''^ 
elected  to  Congress,  and  in  1879  ^^  appointed  by 
President  Hayes  Surveyor-General  of  Minnesota.  He 
leaves  a  widow  and  three  children,  one  of  whom,  Dr. 
Jacob  .H.,  is  at  present  perfecting  his  studies  in  this  city. 


September  13.  1884.] 


THE  MEDICAL  RECORD. 


301 


^jeprartB  0f  MocietUs... 


EIGHTH   SESSION. 
Bifida/  Capenhagefty  Denmark^  August  10-16,  1884. 

REPORTS   OF   SECTIONS. 

(Special  Report  fior  Tkot  Mkdioll  Rbcokd.) 

SECTION    ON    MEDICINE. 

Monday,  August  iith — First  Day. 

The  section  was  called  to  order  by  the  Chairman, 
Profsssor  F.  Trier,  who  briefly  reviewed  the  forth- 
coming work  of  the  members.  He  regretted  the  absence 
d  Professor  Grainger  Stewart,  and  announced  that  the 
following  gentlemen  had  been  nominated  as 

HONORARY  PRESIDBNTS : 

Dre.  Bouchard  and  Jaccoud,  of  Paris ;  L6pine,  of  Lyons ; 
Liebreich,  of  Berlin ;  Liebenneister,  of  Tubingen ;  Bier- 
mer,  of  Breslau ;  Pribram,  of  Prague ;  R.  Bennett,  of  Lon- 
don; H.  Acland,  of  Oxford;  Austin  Flint,  of  New 
York ;  Tommasi  Crudeli,  of  Rome ;  an*  Rosenstein,  of 
Leyden. 

SSCRSTARIES  : 

Dr.  Madsen,  of  Copenhagen,   Secretary-General;  and 
Drs.  Lcyfer^  of  Wurtzbuig ;  Daremberg,  of  Mentone ; 
I.  Owen,  of  London,  additional  secretaries. 
Dr.  S.  Laachk,  of  Christiama,  then  read  a  paper  on 

THE  YALUK  OF  RSCSNT  RXSRARCHIS  ON  BLOOI>-GOR- 
FDSCLIS  IN  THB  PATHOLOGY  OF  ANiBMIC  AND  LBU* 
CKMIC  DISKASBS. 

The  speaker  said  that,  owing  to  tne  labors  of  Vierordt, 
Wdckcr,  Malasses,  and  Hayem,  we  were  now  in  posses- 
noQ  of  a  method  by  which  the  clinician  was  enabled  to 
deteraiine  with  tolerable  exactness,  not  only  the  relative 
sofflber  of  the  blood-corpuscles,  but  also  the  pigmentary 
powers  of  the  blood. 

It  has  been  determined  that,  in 

AN.AMIA  FOLLOWING  HBMORRHAGB, 

the  number  of  red  blood-Kiorpuscles  may  be  reduced  be* 
bw  fifty  per  cent,  without  causing  immediate  death  or 
rendering  impossible  a  restitutio  ad  integrum.  In  the 
process  of  regeneration,  the  formation  of  new  corpuscles 
proceeds  more  rapidly,  as  a  rule,  than  does  that  of  the 
haemoglobin. 

According  to  the  condition  of  the  red  blood-globules, 
we  recogniafie  two  forms  of 

CHLOROSIS. 

In  the  first  form,  pseudochlorosis,  there  is  but  little,  if  any, 
change  in  the  red  corpuscles.  In  the  second  form,  the 
true  chlorosis,  these  bodies  have  undergone  an  un- 
doabted,  and  often  very  marked,  alteration.  Here,  not 
only  the  coloring  properties  of  the  blood,  but  also  the 
number  of  the  corpuscles  are  reduced,  the  former,  how- 
ever, in  the  greatest  degree. 

Tins  division  of  chlorosis  is  of  practical  value,  as  it  is 
in  the  second  variety,  true  chlorosis,  that  iron  exerts  its 
well-known  therapeutical  action.     In 

PERNICIOUS  ANiEMIA 

the  number  of  red  globules  may  sink  below  500,000  per 
cul»c  millimetre  without  causing  immediate  death  or  de- 
stroying all  chances  of  recovery.  A  peculiarity  in  this 
disease  is,  that  the  red  corpuscles  are  on  an  average  larger 
and  contain  more  haemoglobin  than  normal. 

While  the  relations  of  the  white  blood-corpuscles  in 
the  above  conditions  are  not  constant,  their  increase  in 
number  is  the  predominating  symptom  in 

LEUCiBMIA. 

Their  si^  however,  is  variable.  The  red  corpuscles 
may  not  be  altered,  even  in  advanced  stages  of  the  dis- 


ease, and  the  decrease  in  number,  even  when  it  occurs, 
never  reaches  such  an  extreme  degree  in  the  three  first- 
mentioned  afifections.  Arsenic  exerts  a  destructive  ac- 
tion upon  the  white  globules. 

Sir  RiSDEN  Bennett,  of  London,  took  the  Chair 
while  Professor  Austin  Flint,  of  New  York,  read  a 
paper  on 

A  UNIFORM  nomenclature  OF  AUSCULTATORY  SOUNDS  IN 
THE   DIAGNOSIS   OF  DISEASES   OF  THE   CHEST. 

At  the  meeting  of  the  International  Medical  Congress, 
in  London,  in  August,  1881,  the  following  resolution 
was  adopted  by  the  Section  on  Medicine  : 

"  Resolved^  That  a  Committee  be  appointed  to  report 
on  a  uniform  nomenclature  of  auscultatory  sounds  in  the 
diagnosis  of  diseases  of  the  chest.'' 

The  following  were  appointed  members  of  this  Com- 
mittee ;  Professors  Austin  Flint,  of  New  York  ;  Ewald, 
of  Berlin ;  D'Fspine,  of  Geneva ;  and  Drs.  Douglas 
Powel  and  F.  A.  Mahomed,  of  London. 

At  a  meeting  of  the  Committee,  in  London,  it  was 
agreed  that  ,each  member  should  send  his  report  to  the 
Chairman,  who  would  compare  them  and  submit  the  re- 
sults of  such  comparison  to  the  Section  on  Medicine,  at 
the  meeting  of  the  Congress  in  Copenhagen.  Dr.  Flint 
placed  a 

COMPARATIVE  TABLE   OF  THE   DIFFERBNT  LISTS 

where  it  could  be  seen  by  the  members,  and  then  pre- 
sented his  report  upon  the  points  of  difference  and 
agreement  in  these  several  lists.  An  approach  to  uni* 
formitywas  noticed  in  them  all.  The  Committee  had 
evidently  not  needlessly  multiplied  terms.  Those  signs 
which  were  not  included  in  all  lists  were  unimportant, 
with  the  exception  of  cavernous  respiration,  which  was 
wanting  in  the  (merman.  There  were  no  essential  points 
of  difference  in  the  nomenclature.  The  term  subcrepi- 
tant  rSles  was  wanting  in  all  the  lists,  and  was,  ^e 
speaker  thought,  supemuous.  No  variation  existed  in 
the  definition  of  palpation  sounds,  but  there  were  sohae 
differences  in  the  definition  of  the  percussion  sounds. 
^  the  American  list  it  was  stated  that  prolonged  expi- 
ration may  be  high  or  low  in  pitch  ;  the  high  pitch  indi- 
cated consolidation.  R&les  in  the  French  nomenclature 
mean  either  dry  or  moist  sounds ;  in  the  English,  only 
moist  The  definition  of  bronchophony  and  pectoriloquy 
varies  in  the  different  lists. 

It  was  suggested  by  the  speaker  that  the  report  be 
considered  a  provisional  one,  and  that  representatives  of 
other  countries  be  added  to  the  Committee,  to  report  at 
the  next  meeting  of  the  Congress. 

The  President  returned  thanks  for  the  report,  and 
expressed  his  approval  of  the  principles  upon  which  it 
was  drawn  up. 

The  suggestion  of  Dr.  Flint  lais  to  the  provisional  na- 
ture of  the  report  was  submitted  to  the  meeting  and 
adopted. 

Several  of  the  members  criticised  the  report,  as  re- 
garded some  of  its  features. 

Dr.  Flint  replied  that  the  report  was  only  intended 
to  be  a  provisional  one. 

Professor  Tommasi  Crudeli,  of  Rome,  then  read  a 
paper  on 

malarious  INFECTION  IN  MAN. 

The  human  organism  presents  different  degrees  of  re- 
sistance to  the  action  of  the  malarial  poison.  Some- 
times this  is  of  very  high  degree.  It  may  often  be  he- 
reditary in  nations,  appearing  to  be  the  effect  of  natural 
selection.  In  our  day,  however,  this  happy  selection  is 
impossible,  at  least  among  civilized  races,  and  has  been 
replaced  by  specific  degeneration  of  the  inhabitants  of 
malarious  countries.  We  may,  however,  oppose  this 
tendency  to  degeneration  firom  the  effects  of  the  malarial 
poison  by  means  of  a  simple  and  inexpensdve  prophy* 
lactic  medication. 

The  specific  ferment  of  malaria  attacks  directly  the 


302 


THE  MEDICAL  RECORD. 


[September  13, 1884, 


red  blood-corpuscles,  and  causes  necrobiosis  as  the  final 
result  of  a  series  of  alterations  in  the  protoplasm  of  the 
cells.  These  changes  are  characteristic  and  pathog- 
nomonic as  a  sign  of  infection. 

Dr.  a.  Goldschmidt,  of  Lyngby,  Denmark,  exhibited 
a  chart  showing  the  progress  of 

MALARIAL  EPIDEMICS  IN  DENMARK. 

He  related  briefly  the  history  of  these  epidemics  and 
showed  their  close  connection  with  floods  due  to  irrup- 
tion of  the  sea,  or  to  excessive  rainfall. 

Dr.  Kering,  of  St.  Petersburg,  presented  a  commu- 
nication on 

CEREBRO-SPINAL  MENINGITIS. 

He  described  the  etiology,  pathology,  and  symptoms 
of  the  disease.  The  section  on  treatment  contained  no 
very  novel  suggestions. 


Tuesday,  August  i2Th — Second  Day. 

The  Section  was  called  to  order  by  Dr.  Bouchard,  of 
Paris,  who  occupied  the  chair. 

Professor  Ewald,  of  Berlin,  read  a  paper  on  the 

general  management  of  tuberculosis  as  influenced 
BY  recent  investigations  in  experimental  pathol- 
ogy. 

The  author  reviewed  briefly  the  subject  of  the  tuber- 
cle bacillus,  and  then  showed  how  the  theories  of  Koch 
and  his  followers  had  influenced  the  teachings  on  etio- 
logy, diagnosis,  prognosis,  and  treatment. 

Dr.  J.  Grancher,  of  Paris,  then  followed  with  a  com- 
'munication  entitled 

THE  early  diagnosis  OF  PULMONARY  TUBERCULOSIS. 

In  the  pneumonic  form  of  pulmonary  tuberculosis, 
and  in  that  form  which  begins  with  haemoptysis,  or  with 
a  violent  cough,  the  presence  of  the  tubercle  bacillus  is 
an  all-suflicient  diagnostic  sign.  But  in  that  more  com- 
mon form,  in  which  the  commencement  b  very  insidious 
and  unaccompanied  with  expectoration  or  cough,  the 
bacilli  cannot  be  detected.  They  can  only  be  found 
after  expectoration  has  be^n,  and  then  the  diagnosis 
is  certain  enough  without  this  additional  proof. 

The  most  conclusive  sign  in  this  early  stage  is  a  slight 
roughening  with  lowering  of  tone  of  the  inspiratory  mur- 
mur. This  inspiratory  abnormality  is  sufficient  for  a 
probable  diagnosis  when  it  is  distinct,  permanent,  and 
localized  at  the  apex  of  the  lung,  and  when  the  patient 
is  scroflilous  or  presents  an  hereditary  or  other  predis- 
position to  tuberculosis.  This  change  in  the  sub-clavi- 
cular inspiratory  sound  is  found  more  frequently  on  the 
left  than  on  the  right  side.  It  is  true,  however,  that  very 
slight  causes  may  produce  this  alteration  in  the  vesicular 
murmur,  a  transitory  congestion  at  the  menstrual  period, 
for  example.  Hence  it  is  not  well  to  rely  upon  it  too 
strongly  unless  it  is  permanent,  and  unless  an  increased 
probability  is  furnished  by  the  general  condition  of  the 
patient. 

Dr.  Quinlan,  of  Dublin,  presented  a  note  on  the 

treatment  of  pulmonary  consumption. 

The  Library  of  the  Royal  Irish  Academy,  in  Dublin, 
contains  a  large  number  of  manuscripts  in  the  Celtic 
language,  treating  upon  medical  subjects.  In  these, 
mention  is  frequently  made  of  tlie  mullein  plant  as  a 
remedy  in  pulmonary  diseases.  And  at  the  present  day 
it  is  largely  employed  by  the  Irish  in  consumption.  The 
plant  is  known  to  botanists  as  the 

verbascum  thapsus. 

The  author  had  made  a  number  of  experiments  to 
determine  its  efficacy,  and  concluded  that  it  possessed 
considerable  value.  It  is  given  in  infusion  in  milk,  and 
the  leaves  are  smoked  for  the  relief  of  cough. 


Dr.  R.  Shingleton  Smith,  of  Bristol,  read  a  short 
communication  on 

IODOFORM  IN  THE  TREATMENT  OF  PHTHISIS. 

The  drug  had  acted  well  in  his  hands  in  reducing  tern- 
perature,  and  improving  the  general  condition  of  the 
patients. 

Dr«  Jaccoud,  of  Paris,  concluded  the  discussion  of 
pulmonary  phthisis  with  a  paper  on  the 

TREATMENT  OF  TUBERCULOSIS  AS  INFLUENCED  BY  KOCH's 
THEORY. 

He  maintained  that  the  discovery  of  the  bacillus 
tuberculosis  has  been  singularly  sterile  in  its  efiects 
upon  the  treatment  of  phthisis.  He  also  insisted,  in  re- 
gard to  prophylaxis,  that  precautionary  measures  against 
infection  hsid  been  taken  long  ago.  The  main  point  to 
be  held  in  view  was  to  maintain  the  health  of  the  upper 
part  of  the  lung,  and  so  to  render  it  proof  against  infec- 
tion. The  good  effects  of  high  altitudes  were  due  to 
the  fresh  air  and  means  of  exercise.  He  had  himself 
pointed  out  the  freedom  of  such  localities  from  micro- 
organisms in  the  air.  As  to  Koch's  theory,  he  was  of  the 
opinion  that  it  had  great  nosological  interest,  but  that  it 
was  of  no  valu^  in  a  therapeutic  sense.  Possibly  in  the 
future  the  discoveries  of  M.  Pasteur  may  come  to  be  of 
some  prophylactic  importance. 

At  the  afternoon  session  Professor  Austin  Flint 
occupied  the  chair. 

Dr.  W.  B.  Hadden,  of  London,  read  a  paper  on 

MYXOSDBMA  AND  ITS  PATHOLOGY. 

This  is  a  disease  characterized  by  a  general  swollen 
condition  of  the  body  resembling  dropsy,  except  that 
the  parts  do  not  pit  on  pressure.  The  general  expifes- 
sion  of  the  sufferers  is  placid  and  inert — in  a  word,  cre- 
tinoid. The  skin  is  dry  and  harsh^  perspiration  and 
sebaceous  secretion  are  absent^  and  the  hmr,  nails,  and 
teeth  share  in  the  general  malnutrition.  There  is  wast- 
ing of  the  thyroid  gland.  The  temperature  is  almost 
constantly  subnormal.  The  speech  is  slow,  thick,  and 
nasal,  and  the  tongue  seems  too  large  for  the  mouth. 
An  indisposition  to  all  mental  and  bodily  activity  is  one 
of  the  most  striking  features  of  the  disease.  The  appe- 
tite is  poor,  deglutition  is  often  difficult,  and  defecation 
teems  to  be  lundered  by  a  swollen  condition  of  the 
rectal  mucous  membrane. 

The  disease  usually  attacks  adult  women,  but  it  may 
possibly  commencer  during  adolescence.  It  occurs  among 
rich  and  poor,  and  climate  and  race  seem  to  be  without 
influence. 

As  to  morbid  anatomy,  there  is  always  a  diminution  in 
size  of  the  thyroid  gland.  According  to  Ord  there  is 
solid  oedema  of  the  connective  tissues,  and  a  great  in- 
crease in  the  amount  of  mucin ;  hence  the  name  myx- 
cedema.  The  author  believed  that  the  disease  is  depen- 
dent upon  changes  in  the  sympathetic  nervous  system, 
and  he  thought  it  not  unlikely  that  the  thyroid  is  in  some 
relation  vnSi  the  peripheral  sympathetic  nerve-fibres. 
This  view,  he  stated,  had  recently  been  borne  out  by 
post-mortem  evidence. 

An  improvement  has  occasionally  followed  the  em- 
ployment of  jaborandi. 

Professor  Brandes,  of  Copenhagen,  then  exhibited 

A  UVING  SPEaMBN  OF  MYXCEDBMA. 

The  woman  was  forty  years  old  and  had  suffered  from 
the  disease  for  eleven  years.  The  symptoms  began  with 
loss  of  power  in  the  right  hand,  followed  by  a  melancholy 
sluggishness  of  the  intellect.  The  urine  had  contained 
but  very  little  albumen. 

Sir  William  Gull  said  he  had  published  a  paper  on 

CRETINISM   in   ADULTS 

eleven  years  ago.  This  was  what  is  now  called  myx- 
cedema,  but  it  is  not  a  new  disease.   It  is  merely  sporaidic 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


303 


cretmism  in  the  adult.  Cretinism  comes  on  at  any 
period  of  life  and  in  any  degree,  and  is  often  not  recog- 
nized by  the  physician. 

Dr.  Ord,  he  continued,  looking  on  it  as  a  special  dis- 
ease, looked  for  a  special  pathology  and  termed  it  mjx* 
oedema.  The  myxoedema  in  such  cases  is  accidental, 
not  the  essence  of  the  disease. 

Dr.  Mahomed  said  that  Sir  W.  GulPs  earliest  ob- 
servations were  remarkably  confirmed  by  our  latest  knowl- 
edge of  the  diseaa^.  All  the  truth  about  it,  however, 
was  not  contained  in  his  remarks.  Is  the  disease  a  per* 
manent  one  ?  He  thought  it  was  not  necessarily.  In 
some  cases  it  is  not  general,  but  confined  to  some  local 
portions  of  the  body.  The  disease  is  a  perverted  nutri* 
tion,  not  necessarily  a  permanent  pervernon. 

Many  cases  have  been  seen  to  improve  under  treat- 
ment; one  case,,  under  the  speaker's  own  observation, 
dated  from  two  years  back.  At  first  there  was  no  albu- 
men, but  later  the  urine  was  highly  albuminous.  The 
patient  disappeared  for  a  time,  but  a  few  weeks  ago  ap- 
plied for  admission.  At  this  time  the  myxcedema  and 
cretinism  had  quite  disappeared.  There  was  no  albumen 
in  the  urine,  but  the  patient  had  ascites  and  general 
dropsy.  The  abdomen  was  tapped,  the  patient  had 
epileptiform  convulsions  and  died  in  three  days.  At  the 
autopsy  there  was  found  a  thickening  of  the  capsule  of 
the  fiver;  the  kidneys  were  not  granular,  and  there  was 
DO  myxoedema  of  the  tissues.  The  disease  had  evidently 
disappeared. 

He  related  a  second  case,  which  was  under  the  care  of 
Dr.  Goodhart  some  years  ago.  The  patient  came  into 
the  hospital  lately  and  died  there.  She  was  a  withered 
old  woman,  but  presented  no  trace  of  myxoedema.  The 
occurrence  of  mucin  in  the  tissues,,  he  continued,  is 
probably  accidental,  as  Sir  W.  Gull  says,  and  is  the  result 
merely  of  oedema,  as  is  often  seen  in  oedema  from  venous 
obBtniction,  in  which  he  had  often  seen  similar  brawny 
swelling.  It  is  safe  to  say  in  such  a  disease  there  is  an 
affection  of  the  nervous  system,  but  this  is  probably 
secondary,  not  primary.  The  sympathetic  system  is 
probably  at  fiault.  He  confessed  he  would  not  quite  like 
to  see  the  explanation  in  simple  cretinism  or  in  disease 
of  the  thjrroid  gland. 
A  nuniber  of  the  members  then  participated  in  a 

DISCUSSION  ON  TUBERCULOSIS. 

Among  those  who  spoke  were  Professors  Paul  Gutt- 
B»n,  of  Berlin,  A.  Pribram,  of  Prague,  and  I>r.  Croig,  of 
Brassels.  The  discussion  elicited  nothing  of  any  special 
interest. 


The  following  day,  Wednesday,  August  13th,  was  de- 
voted to  excursions  around  Copenhagen,  and  there  was 
consequently  no  work  in  the  Sections. 


Thursday,  August  14TH — Fourth  Day. 

Dr.  Biermer,  of  Breslau,  presided  at  the  opening 
session. 

The  first  paper  of  the  day  was  read  by  Professor  R. 
Upine,  of  Lyons,  and  was  entitled 

CLINICAL  observations   ON    SOME   AUTO-INTOXICATIONS. 

The  different  forms  of  self-poisoning  were  grouped  by 
the  author  under  the  following  heads  : 

1.  Auto-intoxication  in  diabetics,  diabetic  coma.  Allied 
to  this  is  the  form  of  poisoning  sometimes  seen  in  pa- 
tients suffering  from  cancer  of  the  stomach. 

2.  Auto-intoxication  of  intestinal  origin,  intestinal 
septicaemia.  This  may  occur  in  strangulated  hernia, 
artificial  anus,  and  in  various  other  intestinal  lesions, 
even  where  there  is  no  obstruction  m  the  gut. 

3.  Auto-intoxication  of  bronchial  or  vesical  origin. 

.  4-  Auto-intoxication  as  the  morbid  element  in  acute 
infectious  diseases. 


The  author  then  spoke  briefly  of  the  diagnosis  of  these 
different  forms  of  self-poisoning,  and  set  down  the  rules 
for  their  hygienic  and  therapeutical  management. 

The  views  advanced  in  the  paper  were  criticised  by 
Professor  Stadelmann,  of  Konigsberg,  and  £defsin, 
of  Kiel. 

A  communication  was  then  presented  by  Professor 
Liebermeister,  of  Tubingen,  entitled  the 

antipyretic  treatment  of  ACUTE  INFECTIOUS  DISEASES. 

He  said  that  a  great  danger  in  fevers  arose  from  the 
elevated  temperature,  and  it  was  the  problem  for  the 
physician  to  reduce  the  pyrexia.  The  basis  of  antipyretic 
treatment  is  the  direct  withdrawal  of  heat  by  cooling 
baths.  In  many  cases,  however,  the  exhibition  of  an* 
tipyretic  drugs  is  a  useful  auxiliary. 

Professor  Bouchard,  of  Paris,  followed  with  a  paper 
on  the 

ANTISEPTIC  treatment   OF    INFECTIOUS   DISEASES. 

The  paper  was  a  presentment  of  the  views  of  Dr.  Warf- 
vinge,  of  Stockholm.  He  showed  that  the  high  tem- 
perature is  not  the  essence  of  the  disease,  but  is  only  an 
important  symptom,  and  consequently  is  not  the  main 
point  for  attack  in  treatment.  It  is  impossible  to  obtain 
a  reduction  of  temperature  by  cold  baths  except  by  re- 
peating them  with  great  frequency.  It  is  more  rational 
to  employ  internal  remedies,  which  at  the  same  time 
reduce  the  temperature  and  repress  the  production  of 
heat.  It  is  most  probable  that  all  infectious  diseases  are 
due  to  the  presence  of  inferior  organisms  within  the 
economy.  It  is  therefore  more  rational  to  attack  them 
as  the  cause,  rather  than  the  fever  as  a  symptom.  But 
it  is  known  that  the  so-called  antipyretics  are  also  among 
our  most  powerful  antiseptics,  and  this  probably  explains 
their  mode  of  action.  Although  any  possible  concentration 
of  a  dni^  within  the  body  is  too  weak  to  kill  these  organ- 
isniS)  it  is  probably  strong  enough  to  so  paralyze  them 
that  they  become  incapable  of  exerting  their  deleterious 
effects.  The  system  thus  gains  time  to  recuperate,  and 
finally  becomes  strong  enough  to  expel  the  already 
weakened  micro-c^ganisms. 

The  writer  then  gave  a  r6sum6  of  Dr.  Warfvinge's 
experiments  with  various  antiseptics  in  fevers.  He 
regarded  phenic  acid  in  the  treatment  of  typhoid  fever 
with  especial  favor.  Alum  he  had  found  of  great  service 
in  the  treatment  of  pertussis. 

At  the  afternoon  session.  Professor  LApine,  of 
Lyons,  occupied  the  chair. 

The  greater  part  of  the  session  was  occupied  by  a 

DISCUSSION  ON   COLD   BATHS   IN   FEVERS, 

as  advocated  in  Professor  Liebermeister's  paper.     Some 
of  the  speakers  animadverted  very  strongly  on  the  dan- 
gers of  this  method,  and  expressed  a  decided  preference 
for  the  employment  of  internal  antipyretics. 
Dr.  Pribram,  of  Prague,  spoke  of  the  value  of 

ANTIPYRIN. 

This  was  a  new  remedy,  but  the  results  of  a  number  of 
experiments  by  different  observers  would  seem  to  show 
that  we  possess  in  this  artificially  formed  substance,  an 
antipyretic  of  undoubted  worth. 

Professor  Liebermeister  replied  briefly  to  th«  criti- 
cisms of  the  cold  water  treatment,  and  defended  with 
some  spirit  its  claims  as  the  best  method  for  reducing 
temperature  in  fevers. 

Dr.  Brondet,  of  Paris,  read  a  paper  on  the 

TREATMENT     OF     INTESTINAL     OBSTRUCTIONS     BY    ELEC- 
TRICITY. 

He  detailed  the  methods  employed  by  him,  and  illus- 
trated his  remarks  by  a  number  of  cases  happily  relieved 
by  this  treatment. 


304 


THE  MEDICAL  RECORD. 


[September  13,  1884, 


Friday,  August  15TH — Fifth  Day. 

Dr.  Pribram,  of  Prague,  was  in  the  chair. 
Professor  Rosenstein,  of  Leyden,  presented  a  paper 


on 


MALARIOUS    infection    IN    MAN. 


This  was  followed  by  an  interesting  paper  by  Profes- 
sor With,  of  Copenhagen,  on 

PERrrONITIS   RESULTING    FROM   DISEASES  OF  THE   VERMI- 
FORM  APPENDIX. 

The  author  said  that  inflammation  of  the  peritoneum  in 
the  ri^t  iliac  fossa,  known  by  the  name  of  perityphlitis, 
originates  most  frequently  from  ulceration  and  perfora- 
tion of  the  appendix  vermiformis.  Peritonitis  of  such  an 
origin  is  called  appendicular  peritonitb.  It  presents 
itsetf  under  three  usually  distinct  forms  or  stages,  to  wit, 
adhesive,  local,  and  general  appendicular  peritonitis. 
The  first  occurs  prior  to  perforation,  and  the  last  subse- 
quent to  this  acadent 

As  regards  treatment,  the  primary  indication  is  to 
prevent,  as  far  as  possible,  all  movements  of  the  intestine. 
With  this  object  in  view,  it  is  necessary  to  give  sufficiently 
large  doses  of  opium  or  morphine,  and  also  to  abstain 
from  the  use  of  laxatives  or  enemata.  The  bowels  must 
be  kept  confined  for  many  days,  sometimes  as  many  as 
twenty-four.  If  this  treatment  be  pursued,  the  necessity 
for  f  urgical  intervention  will  be  greatly  restricted. 

Frofsssor  Austin  Funt,  of  New  York,  desired  to 
refer  to  a  point  in  the  diagnosis  of  perforation  of  the 
inlestine,  viz., 

THE    persistence    OF    THE    HEPATIC    DULNBSS   ON   PER- 
CUSSION, 

as  a  proof  that  perforation  has  not  taken  place.  A  very 
small  quantity  of  air  in  the  peritoneal  cavity  sufficed  to 
abolish  hepatic  dulneas.  This  might  be  proved  by  in- 
jecting air  through  a  trocar  in  tiie  dead  subject  A 
tjonpanitic  resonance  over  the  whole  hepatic  region  was 
not  proofs  however,  that  perforation  had  taken  place,  for 
when  the  colon  is  distended,  a  tympanitic  resonance  often 
extends  up  to  the  base  of  the  lung.  Another  point  as  to 
the 

TREATMENT  WITH  OPIUM, 

ajQd  allowing  the  bowels  to  remiun  constipated  for  a  long 
time,  unless  they  acted  spontaneously.  This  was  long 
ago  introduced  and  practised  in  New  York  by  Dr.Alonzo 
Clark,  who  ascertained  that  patients  could  tolerate  an 
enormous  amount  of  this  drug.  The  dose  should  be 
gradually  increased  so  as  to  avoid  a  toxical  degree  of 
narcotism.  The  rationale  of  the  treatment  was  com- 
plete arrest  of  peristaltic  action,  to  "  put  the  bowels  in 
splints."  Although  cathartics  or  laxatives  were  danger- 
ous, the  rectum  might  sometimes  be  emptied  by  a  simple 
enema,  which  did  not  excite  the  intestine  above  a  peri- 
staltic action. 

The  paper  was  further  discussed  by  Drs.  Ewald,  of 
Berlin,  and  Mahomed,  of  London. 

Dr.  J.  Grancher,  of  Paris,  followed  with  a  communi- 
cation on 

SUBACUTE   pneumonia. 

Subacute  inflammation  of  the  lung,  so-called  spleno- 
pneumonia,  has  no  well-defined  position  in  pathological 
classification.  It  is  confounded  now  w^th  pulmonary 
congestion,  and  again  with  the  pleurisy  which  often  ac- 
companies it  as  a  complication.  It  differs,  however, 
from  acute  congestion  and  passive  stasis  as  much  as 
from  acute  pneumonia  and  pleurisy.  More  nearly  allied 
to  broncho-pneumonia,  it  is  yet  easily  distinguished  from 
it  by  its  localization  in  one  lun^,  its  fixedness,  as  well  as 
the  general  character  of  its  clinical  features.  The  mode 
of  origin,  the  pain  in  the  side,  dyspnoea,  fever,  and  dry 
cough  are  symptoms  which  resemble  more  or  less  those 
of  pleurisy  of  medium  intensity.      But  the  dyspnoea  is 


more  intense  and  the  fever  more  active  and  showing 
greater  oscillations.  The  general  condition  is  more 
grave  than  it  is  in  pleurisy.  Finally,  there  is  often  al- 
bumen in  the  urine.  The  disease  k^ts  about  five  or  six 
weeks. 

The  physical  signs  over  the  seat  of  disease  are  dul- 
ness,  absence  or  diminution  of  vocal  resonance,  a  soft 
souffle,  broncho-aegophony,  and  some  crepitant  r^es  on 
inspiration.  The  signs  in  the  neighborhood  of  the  pul- 
monary lesion  are :  below  the  point  and  to  the  left,  the 
preservation  of  Traube's  space ;  on  the  n^ht,  the  per- 
sistence of  the  liver  in  its  physiological  position.  Above 
this  point,  in  the  sub-clavicular  and  scapular  regions, 
there  is.  a  noticeable  enfeeblement  of  the  inspiratory 
murmur,  with  tympanism  and  a  permanent  or  transitory 
exaggeration  of  the  vocal  vibrations.  The  opposite  long 
is  healthy. 

In  subacute  pneumonia,  pure  and  simple,  puncture  of 
the  chest-walls  with  the  needle  of  the  hypodermic  syringe 
gives  exit  only  to  air  and  blood.  This  d^  i«  not,  how- 
ever, always  of  practical  value,  as  there  is  often  a  more 
or  less  extensive  pleuritic  effusion. 

On  Friday  morning,  from  10  to  12  o'clock.  Professor 
Tommasi  Crudbli  gave  a  demonstration  at  die  School 
of  Technology  of  microscopic  specimens  showing  the 

CHANGES   IN  THE   RED    BLOOD-CORPUSCLES  IN   MALARU 

in  the  human  subject  In  each  preparation  the  healthy 
corpuscles  were  unstained,  but  in  various  parti  of  the 
field  could  be  seen  other  corpuscles  containing  one  or 
more  nnall  colored  particles.  These  particles,  he  thought, 
were  probably  the  germs  of  a  bacillus. 


Saturday,  August  i6th — Sixth  Day. 

There  was  but  one  session  .this  day.     The  princq^ 

Eaper  was  by  Professor  Grainger  Stewart,  of  Edm- 
urgh,  on  the 

influence  of  acute  INFECnOUS    DISEASES    UPON  THI 
kidneys   AND  their  FUNCTIOKS. 

The  author  said  that  acute  infectious  diseases  were 
now  believed  to  be  due  to  the  introduction  into  the  sys- 
tem of  poisonous  matters  which  are  capable,  under  &vor- 
able  circumstances,  of  reproducing  themselves.  These 
diseases  influence  the  kidneys  in  two  ways  :  by  producing 
organic,  and  hence  grave  and  permanent,  or  functional 
changes.     In  considering  the 

ORGANIC  CHANGES 

he  first  described  the  anatomical  alterations.  The  tub- 
ules  might  be  normal  in  appearance,  but  were  more 
usually  the  seat  of  lesions  varying  from  a  slight  cloudy 
swelling  of  the  epithelium  to  the  most  pronounced  in- 
flammation, with  fatty  degeneration  and  breaking  down 
of  the  cells.  In  some  cases  the  tubules  contained  nu- 
merous parasitic  organisms.  In  the  Malpighian  cor- 
puscles 5ie  vascular  tufts  were  compressed  by  swelling 
of  surrounding  parts.  In  some  cases  there  was  marked 
proliferation  of  the  fibrous  tissue  of  the  stroma.  The 
next  question  was : 

WHAT   IS   THE   RELATION   OF   GERMS  TO  THESE  CHANGES? 

It  is  certain  that  micro-organisms  may  be  found  in 
great  numbers  in  the  kidneys  m  certain  of  the  acute  in- 
fectious diseases,  yet  the  author  himself  was  convinced, 
from  examinations  that  he  had  made  in  conjunction  with 
Dr.  Stacey  Wilson,  that  fatal  diphtheria  with  albumi- 
nuria was  not  necessarily  attended  with  the  presence  of 
organisms  in  the  kidney.  He  was  also  convinced  that 
well-marked  scarlatinal  nephritis  might  run  its  course 
without  any  organisms  being  present.  It  seems  most 
probable  that  a  poisonous  substance  is  developed  in 
the  course  of  the  disease  by  which  the  kidney  is  irri- 
tated. 


Sqrtcmber  13,  1884.  J 


THE  MEDICAL  RECORD, 


305 


The  third  question  was  : 

DO  THB  INFECTIOUS  PROCESSES  DIFFER  CLINICALLY 
FROM  ORDINARY  NON-INFECTIOUS  RENAL  INFLAMMA- 
TION? 

The  ordinary  symptoms  are  the  same,  but,  strange  to 
say,  there  appeared  to  be  no  room  for  doubt  that  viru- 
lent organisms  were  often  present  in  the  urine  of  patients 
saffering  from  acute  infectious  diseases.  The  author 
was  unable  to  explain  the  fact,  and  thought  it  might  lead 
to  a  reopening  of  the  question  of  micro-organisms  in  the 
kidneys,  and  possibly  overthrow  the  opinions  just  enun- 
ciated by  him. 

He  next  considered  the  question  of 

FUNCTIONAL  ALBUMINURIA, 

occurring  in  the  course  of  acute  infectious  diseases. 
This  might  result  from  sli^t  changes  in  the  renal  struc- 
tures which  speedily  subsided,  and  were  consequently 
never  the  subject  of  post-mortem  examination.  In 
other  cases  it  was  the  result  of  high  temperature  with 
txansudation  of  albuminous  materials  through  the  renal 
vessels.  Lastly,  in  some  cases  it  might  be  due  to  an 
alteration  of  the  blood  serum  from  chemical  causes,  by 
reason  of  which  transudation  through  the  vessels  occurred 
more  readily  than  in  health. 
The  Section  then  adjourned  at  i  o'clock. 


^jew  %nsthxmmte. 

A  SIMPLE  STOMACH-PUMP. 
By  D.  H.  GOODWILLIE,  M.D., 

NEW  YORK. 


The  accompanying  cut  represents  a  simple  and  efficient 
pump  for  the  removal  of  blood  and  mucus  from  the 
stomach,  to  prevent  vomiting,  after  operations  on  the 
nose  and  mouth,  particularly  that  of  staphylorraphy.  It 
can  also  be  readily  used  in  the  bladder  or  rectum.  It  con- 
sists of  a  heavy  rubber  ball  of  two-ounce  capacity,  having 
an  in- valve  (I)  and  an  out-valve  (O).  To  this  is  attached 
by  a  simple  hard  rubber  connection  the  stomach,  bladder, 
or  rectum  tube,  of  flexible  rubber,  of  diflFerent  sizes  for 
children  or  adults.  The  tube  at  the^other  end  to  be 
placed  in  the  vessel  of  liquid. 

When  it  is  to  be  used,  pass  the  disconnected  stomach 
tnbe  into  the  stomach.  Fill  the  connected  ball  and  other 
tube  from  the  vessel,  keep  it  upright,  with  the  tube  down- 
ward, connect  it  to  the  stomach-tube,  and  gently  force  the 
required  quantity  of  liquid  into  the  stomach.  Then  dis- 
joint the  tubes,  reverse  the  ball,  rejoin  tubes,  and  gently 
pump  out     Repeat  if  necessary. 

Its  advantages  are,  that  it  is  simple  in  structure,|^as 
extra  large  valves,  good  strength,  is  always  ready,  and 
easily  used. 


The  Record  not  Beaten  after  all. — Dr.  L.  A. 
lUxienstein,  of  this  city,  sends  a  note  calling  attention  to 
a  case  reported  by  him  in  the  American  Journal  of  Ob- 
stetrics.  It  was  that  of  a  polycystic  ovarian  tumor  weigh- 
ing one  hundred  and  forty-six  pounds.  "  So,'*  writes  our 
correspondent,  **  Dr.  C.  C.  Stockard's  case,  published  in 
The  Record  of  August  i6th,  is  not  the  largest  on  record, 
and  New  York  still  holds  the  champion  cup,  as  far  as 
laige  tumors  are  concerned.". 


A  NEW  SOFT  RUBBER  VELVET- EYED  TUBE 
FOR  INJECTING  OR  MEASURING  THE 
UTERUS. 

By  W.  THORNTON  PARKER,  M.D., 

ACTING  ASSISTANT  SURGEON,   V.  S.  ASMV. 

Considerable'  attention  has  been  given  of  late  to  the 
subject  of  intra-uterine  injections.  Tlie  necessity  for 
the  accurate  measurement  of  the  uterus  in  a  great  many 
gynecological  cases  requires  a  safe  instrument 
All  writers  on  diseases  of  women  recognize  the 
dangers  in  the  use  of  the  metallic  sound. 

In  too  many  instances  the  sound  is  needlessly 
used,  and  often  by  rough  and  unskilful  operators. 

It  is  impossible  to  estimate  the  injury  resulting 
from  such  meddling. 

^'  The  emplo3rment  of  the  uterine  sound  shouk) 
be  resorted  to  with  great  care  and  gentleness,  and 
only  when  we  are  Ukely  to  gain  some  information 
from  its  use  that  we  cannot  otherwise  gain. 
Several  instances  have  been  recorded  where  the 
point  has  been  made  to  perforate  the  wall  of  the  , 
uterus.  This  accident  is  most  likely  to  happen  ^| 
when  the  organ  is  in  a  softened  state,  such  as 
occurs  during  the  fatty  degeneration  of  sub-involu- 
tion following  abortion  or  parturition,  or  in  the 
ulcerative  stage  of  cancer.  It  has  been  suggested 
that  the  point  may  have  passed  along  a  dilated 
Fallopian  tube,  but  although  this  may  explain  some 
few  cases  where  the  point  of  the  sound  has  been 
felt  beneath  the  abdominal  wall,  there  is  HtiU 
doubt  but  that  in  the  majority  of  suck  cases  perfo- 
ration of  the  uterine  wall  has  actually  occurred.*^^ 

'^  If  the  uterus  be  in  its  normal  position^  and 
}iie  sound  he  used  by  a  skilful  hand^  the  opera- 
tion is  not  difficult.  But  it .  is  not  the  healthy 
titerus  which  we  are  generally  called  upon  to  ex- 
plofe^^  If  the  organ  be  displaced,  the  difficulties 
and  dangers  attending  the  employment  of  the 
sound  are  considerable.  .  The  facts  which  may  be  ascer- 
tained, by  the  sound,  are  these :  j,  the  capacity  of  the 
iilenis;  2,  the  existence  of  growths  within  it;  3,  de- 
viation of  the  course  of  its  canal ;  4,  differentiation  of 
displacements  from  uterine  tumors;  5,  the  mobility  of 
the  uterus. **• 

.  The  great  impprtaoce  of  these  facts  with  reference 
to  diagnosis  is  evident,  and  one  would  suppose  that  an 
instrument  revealing  so  much  would  be  universally  em- 
ployed. Such,  however,  is  not  by  any  means  the  case. 
By  adepts  it  is  commonly  resorted  to,  but  in  general 
practice  will  be  found  many,  indeed  a  majority,  who  do 
not  employ  W  from  fear  of  its  results^  the  difficulty  of  its 
introduction,  and  uncertainty  as  to  its  revelations. 

*'  Some  remarkable  accidents  prove  the  necessity  of 
exerting  the  utmost  care  and  delicacy  of  touch  in  using 
the  sound.  The  point  of  the  instrument  has  actually 
perforated  the  fundus  of  the  uterus.  Two  such  cases 
were  observed  by  Schroeder.  In  both  the  sound  went 
without  force  sixteen  to  seventeen  centimetres  deep,  and 
its  knob  was  felt  through  the  thin  abdominal  walls.  The 
most  careful  and  judicious  use  of  the  sound  is  sometimes 
attended  and  followed  by  intense  pain.  Metritis  has  oc- 
curred, and  this  even  when  there  was  no  reason  to  infer 
that  the  wall  had  been  perforated.  That  fatal  accidents 
have  occurred  from  the  use  of  the  sound  can  hardly  be 
doubtful:'^ 

It  has  occurred  to  me  that  some  improvement  is  re- 
quired in  our  instruments  for  intra-uterine  injection,  and 
also  that  some  gentler  if  not  more  precise  method  might 
be  employed  in  measuring  the  uterus  than  that  of  the 
metal  sound.  The  accompanying  very  simple  contrivance 
has  been  devised,  which  may  be  found  useful  in  the 
operations  for  which  it  is  intended. 

'  Edis :  Diseases  of  Women,  p.  xx.  x88i. 

3  Thomas  :  Diseases  of  Women,  p.  loo.    Fifth  Edition^  z8£c. 

"  Barnes  :  Diseases  of  Women,  p.  142  et  seq. 


3o6 


THE  MEDICAL  RECORD. 


[September  13,  1884. 


This  uterine  injecting  and  measuring  tube  is  made  of 
j^iable  rubber  somewhat  sti£fer  than  the  rubber  catheter. 
It  conespoiids  in  diameter  to  the  No.  13  Tiemann  &  Go's 
American  Scale,  aldicmi^  it  can  be  used  larger  or  smaller 
in  diameter  if  desired.  It.  is  ten  inches  long,  and  fits  se- 
curely, when  needed  for  injecting  purposes^  over  the 
nozzle  of  the  common  hard  rubber  uterine  syringe.  For 
about  six  inches  it  is  marked  with  one-eighth,  one-fourth, 
one-half,  and  one  inch  divisions.  There  is  no  terminal 
orifice,  but  there  are  twelve  **  velvet-eyed  "  apertures  to 
permit  the  escape  of  the  fluid  for  injection  obliquely 
backward.  The  tube  can  be  easily  and  painlessly  in- 
troduced into  the  uterus,  and  by  slipping  the  black  hard 
rubber  ring  forward  against  the  os,  the  length  of  the 
uterine  canal  can  be  accurately  determined.  The  tube 
being  flexible,  and  the  orifices  "velvet-eyed,"  the  danger 
from  injury  to  the  uterus  is  reduced  to  the  minimum. 
The  wire  provided  for  use,  when  used  as  a  measurer^ 
will  be  found  sufliciently  stiff  to  make  the  instrument  a 
very  acceptable  sound.  If  this  measuring  tube  can 
sometimes  be  substituted  for  the  more  dangerous  metal- 
lic sound,  and  with  equal  accuracy,  the  object  of  its 
manufacture  will  have  been  accomplished. 

FoKT  Union,  New  Mbx. 


A  NEW  SPRAY  PRODUCER. 
By  CYRUS  EDSON,  M.D., 

MRW  YORK. 

The  instrument  represented  by  the  accompanying  il- 
~  lustration  is  a  modification  of  the 
ordinary  nasal  application,  and 
has  been  designed  for  making  me- 
dicinal applications  to  the  mucous 
surfaces  of  the  nares,  pharynx,  and 
larynx.  It  consists  of  a  hard  rub- 
ber tube,  about  five  inches  long, 
having  an  oblong  bulbous  extrem- 
ity, divided  near  its  proximal  end 
by  a  thread  and  screw  joint. 

To  use  the  instrument  the  bulb 
is  unscrewed  and  packed  with  ab- 
sorbent cotton  or  sponge,  which 
is  then  saturated  with  the  chosen 
solution.  The  bulb  having  been 
screwed  in  place,  the  instrument 
is  attached  to  a  compressed  air- 
receiver  and  used  like  a  Sass" 
tube. 

The  spray  is  somewhat  coarser 
than  that  produced  by  the  latter 
atomizer.  A  tip  is  provided  for 
delivering  it  in  any  direction. 

To  the  practitioner  who  is  not 
a  throat  specialist  it  commends 
itself  for  the  following  reasons  :  It 
is  practically  indestructible ;  it  is 
not  liable  to  become  clogged ;  it 
does  not  require  specially  con- 
structed bottles  for  the  medicinal 
solutions.     It  is  an  excellent  powder  blower. 


Glass  in  Pepsin  Packages. — Dr.  S.  E.  Campbell^  of 
South  Bay  City,  Mich.,  sends  us  a  note  of  warning  to 
physicians  who  dispense  their  own  pepsin.  A  medical 
student  suflering  from  gastric  insufficiency  (we  have  never 
met  with  that  trouble  in  medical  students,  by  the  way) 
purchased  a  pound  package  of  saccharated  pepsin  made 
by  a  New  York  firm.  In  taking  his  dose  he  noticed  oc^ 
casionally  something  hard  in  his  mouth.  Finally  he 
sifted  the  pepsin  and  found  a  number  of  bits  of  broken 
test-tube.  We  presume  that  the  mixture  is  not  a  common 
one,  but  a  word  of  warning  is  not  out  of  place. 


(S^ovKzspon&entz. 


INTERNATIONAL   MEDICAL   CONGRESS 
NOTES. 

(From  our  Own  Correspondent) 

Copenhagen,  Denmark,  Aupitt  23,  1884. 
THE  OPENING  ON  SUNDAY — THE  EXCURSION  IN  THE 
MIDDLE  09  THE  WEEK — PROFESSOR  LANGE,  THE  SEC- 
RETARY-GBNEEAL — HOW  HE  USED  HIS  OFFICIAL  PO- 
SITION IN  HINDERING  THE  PRESS  IN  OBTAINING 
LEGITIMATE  INFORIIATION  —  THE  SECRETARIES  OF 
SECTIONS  IN  THE  R6lE  OF  OBSTRUCTIONISTS — DIFFI- 
CULTIES IN  OBTAINING  INFORMATION  GENERALLY— 
THE  BANQUET  IN  THE  TENT  ANP  TSS  NOVEL  WAY 
OF  RESPONDING  TO  TOASTS— BRILLIANT  RECEPTIOHS 
AND   FREE   LUNCHES. 

In  my  previous  letter,  hastily  written  before  the  dosing 
of  the  mail,  I  endeavored  to  give  a  general  idea  of  the 
great  medical  meeting  here,  but  I  found  on  looking  over 
my  notes  that  there  are  many  things  which  I  might  have 
said  but  for  the  hurry. 

The  choosing  of  Sunday  as  the  day  for  the  opening 
ceremony  was  not  much  in  accordance  with  American 
or  British  notions,  but  I  suppose  it  did  not  seem  outri  to 
Continentals.  It  certainly  would  not  have  been  done  in 
America  or  England.  Tho  singing  of  a  cantata  after  the 
speeches  and  before  the  Congress  was  declared  open  had 
a  novel  but  very  pleasing  effect 

On  the  whole,  those  who  attended  the  recent  Congress 
have  no  reason  to  complain  of  the  Danes.  Judging  of 
them  by  the  Congress  week,  one  cannot  but  pronounce 
them  a  most  hospitable  nation.  Receptions,  banquets, 
excursions  followed  one  another  in  rapid  succession, 
alternating  with  the  more  serious  work  of  the  Congress. 
The  idea  of  giving  up  a  whole  day  to  excursions  in  the 
middle  of  the  week  was  certainly  somewhat  novel,  but 
the  result  was  most  enjoyable. 

Professor  Lange,  the  Secretary-General,  made  a 
speech  at  the  opening  ceremony.  He  was  very  nervous, 
and  spoke  so  low  that  no  one  more  than  a  few  yards 
from  him  could  hear  a  word  he  said,  and  altogether 
made  rather  a  poor  impression  as  an  orator.  Before 
leaving  Professor  Lange  I  desire  to  place  on  record  that, 
in  his  official  capacity  of  secretary,  instead  of  affording 
facilities  to  representatives  of  the  press  he  either  would 
not  or  could  not  give  them  any  assistance,  but  ap- 
parently endeavored  to  obstruct  them.  He  speaks 
English  fluently,  so  he  cannot  plead  as  an  excuse  that 
he  did  not  understand  the  English-speaking  journalists 
who  applied  to  him.  Several  of  the  secretaries  of  sec^ 
tions  also  were  very  loth  to  communicate  what  they 
knew  about  the  proceedings.  Some  of  them  excused 
themselves  by  saying  they  had  been  away  part  of  the 
time.  How  a  complete  set  of  the  transactions  will  be 
prepared  I  am  sure  I  know  not. 

One  of  your  London  contemporaries  sent  a  repre- 
sentative accompanied  by  a  short-hand  writer.  The 
former  found  such  insurmountable  difficulties  in  getting 
information  that,  finding  his  short-hand  writer  practically 
useless,  he  told  him  he  might  as  well  go  off  to  Norway, 
or  somewhere  else,  and  take  a  holiday. 

The  sections  unfortunately  did  not  meet  near  together, 
but  in  three  different  places,  any  one  of  whidi  was 
roughly  speaking  a  mile  from  either  of  the  others.  As 
the  fourteen  sections  all  met  simultaneously,  your  readers 
can  form  some  idea  of  the  difficulties  of  getring  infonna^ 
tion  from  each. 

Passing  to  more  pleasing  recollections  let  me  say  that 
the  trip  to  Elsinore,  in  which  nearly  all  the  members  of 
the  Congress  participated,  was  most  enjoyable.  The 
luncheon  in  the  Kronberg  Castle  was  laid  in  twenty-two 
rooms. 

Perhaps  of  all  the  scenes  in  connection  with  the  Con- 


September  13,  1884.] 


THE  MEDICAL  RECORD. 


307 


2res8  the  banquet  in  the  tent  on  the  Custom  House  Quay 
^  be  the  longest  remembered  by  those  who  were 
present.  This  was  on  Thursday  afternoon.  It  began  at 
^ve  o'clock  and  terminated  about  half-past  eight  To 
^cconmodatt  the  immense  nimiber  present — about  two 
thousand,  including  visitors — forty-two  tables  were  laid. 
To  wait  on  the  army  of  guests  one  hundred  and  sixty- 
eight  servants  were  provided,  who  served  the  successive 
courses  as  the  signal  was  given  by  ringing  a  large  bell. 
The  menu  was  sumptuous,  but  most  unlike  an  average 
London  or  Parisian  dinner.  The  speeches,  too,  were 
given  in  a  most  eccentric  manner.  The  guests  were  not 
aHoired  to  dine  in  peace  and  then  enjoy  the  '*  feast  of 
reason  "  and  "  flow  of  soul "  afterward,  but  they  were  in- 
terspersed between  the  courses,  sandwiched,  in  fact, 
between  the  viands  provided  for  mere  bodily  refreshment. 
Thej  began  directly  after  the  soup  had  been  served  and 
partaken  of,  and  from  thence  onward  to  the  conclusion 
of  the  meal  either  a  speech,  a  song,  or  music  diversified 
the  intervals  between  the  courses.  When  a  speech  was 
being  delivered  by  an  eminent  member  the  dinner  was 
forgotten  and  the  assembly  vacated  their  seats  en  masse 
and  nished  to  the  other  end  of  the  immense  tent  so  as 
not  to  lose  a  word.  Venerable  and  distinguished  mem- 
bers of  the  profession  were  seen  running  helter-skelter 
like  so  many  schoolboys..  I  saw  one  specimen  of  the 
latter  genus  present  by  the  way — apparently  a  son  of  one 
of  the  members  present.  Sir  James  Paget  spoke  to  him 
and  said,  "  I  am  very  glad  to  see  you,  my  boy.  We  shall 
all  of  us  remember  diis  occasion  to  the  end  of  our  lives, 
but  you,  being  the  youngest  of  us,  will  remember  it  longer 
than  any  of  us."     Virchow  also  spoke  to  him. 

Despite  the  successive  interruptions  the  vast  dinner 
came  to  an  end  at  last  All  then  embarked  on  board 
the  steamers  provided  and  went  by  way  of  the  canal  to 
the  Tivoli  Gardens.  The  banks  were  lined  with  specta- 
tors, who  cheered  loudly  as  the  Congress  passed.  Many 
boatmen  were  on  the  canal  and  cheered  and  saluted  with 
their  oars  as  they  passed  us.  Many  of  them  burnt  blue 
and  red  lights.  Rockets  and  other  fireworks  were  dis- 
diaiged,  illuminations  were  displayed,  and  the  electric 
Hght  shone  brightly  from  many  vessels  and  houses.  At 
Tivoli  about  forty  thousand  people  had  assembled.  The 
whole  formed  a  never-to-be-forgotten  sight.  The  closing 
festival  on  Saturday  was  also  brilliant. 

I  must  not  omit  to  mention  that  throughout  the  Con- 
gress firee  lunches  were  provided  for  such  as  chose  to 
partake  of  them.  Free  railway  passes  were  also  granted 
from  Copenhagen  to  the  frontier. 

Despite  a  few  drawbacks,  I  think  I  may  safely  say, 
in  conclusion,  that  all  who  took  part  in  the  Congress  of 
1884  will  remember  with  pleasure  the  courtesies  and 
hospitalities  shown  them  by  the  Danes  in  their  beautiful 
capital,  Copenhagen. 

Muriate  of  Ammonia. — It  increases  the  secretion  of 
mucus  from  the  alimentary  canal,  and  is  supposed  to  render 
the  blood  less  plastic  and  coagulable,  without  impairing 
the  structure  of  the  corpuscles.  Its  habitual  use  causes 
emaciation^  renders  all  the  secretions  freer  and  more 
abundant,  and  exerts  an  alterative  and  absorbent  action, 
especially  on  the  connective  tissues,  in  hyperplasia  and 
cirrhosis  of  many  organs.  It  has  even  exerted  some 
beneficial  influence  upon  fibrous  tumors  of  the  uterus, 
and  much  more  upon  chronic  engorgement  of  that  organ. 
Its  slow  but  steady  modification  of  the  nutrition  of  the 
connective  tissues  has  been  seen  in  chronic  enlargements 
of  the  liver,  spleen,  prostate,  thyroid,  and  other  enlarge- 
ments. It  cures  many  cases  of  gleet  and  if  any  internal 
remedy  will  relieve  strictures  of  the  urethra,  this  is  the 
one  most  apt  to  do  it  It  cures  some  cases  of  neuralgia 
depending  upon  thickening  of  the  neurilemma,  and  is  one 
of  the  best  remedies  in  fibrous  phthisis.  If  other  reme- 
dies fiiil,  it  should  be  tried  in  sclerosis  of  the  cord  and 
hnin  depending  upon  thickening  and  induration  of  the 
neuroglia. 


Official  List  cf  Changes  in  the  SiaHons  and  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army^ 
from  August  31  to  September  6,  1884. 

Byrne,  Charles  C,  Major  and  Surgeon.  Relieved 
from  duty  in  Department  of  California,  and  to  report  in 
person  to  the  Commanding  General,  Department  of  the 
Platte,  for  assignment  to  duty.  S.  O.  207,  A.  G.  O., 
September  3,  1884. 

Town,  F.  L.,  Major  and  Surgeon.  Relieved  firom  duty 
in  Department  of  the  Columbia,  and  to  report  in  person 
to  the  Commanding  General,  Department  of  Texas,  for 
assignment  to  duty.  S.  O.  207,  C.  S.,  A.  G.  O.  Granted 
leave  of  absence  for  twenty-five  days.  S.  O.  127,  De- 
partment of  the  Columbia,  August  25,  1884. 

Havard,  Valery,  Captain  and  Assistant  Surgeon. 
Relieved  from  duty  in  Department  of  Texas,  and  to  re- 
port in  person  to  the  Commanding  General,  Department 
of  the  East,  for  assignment  to  duty.  S.  O.  207,  C.  S., 
A.  G.  O. 

Hall,  William  R.,  Captain  and  Assistant  Surgeon. 
Relieved  from  duty  in  Department  of  Texas,  and  to  re- 
port in  person,  on  October  i,  1884,  to  the  Superintendent 
General  Recruiting  Service  in  New  York  City,  for  duty  at 
David's  Island,  N,  Y.,  relieving  Assistant  Surgeon  M.  E. 
Taylor  from  duty  at  that  station.  S.  O.  207,  C  S., 
A.  G.  O. 

Hopkins,  William  £.,  First  Lieutenant  and  Assistant 
Surgeon.  The  leave  of  absence  granted  him  in  S.  O.  67, 
August  7,  1884,  Department  of  Arizona,  is  extended  one 
month.     S.  O.  204,  A.  G.  O.,  August  30,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  5. 
Nuvy^  during  the  week  ending  September  6,'  1884. 

RixEY,  P.  M.,  Passed  Assistant  Surgeon.  From  special 
duty  at  Washington,  D.  C,  September  8  th,  tp  the  Lan- 
caster, European  Squadron. 

Oberly,  a.  S.,  Surgeon.  From  the  Richmond,  August 
30th,  and  wait  orders. 

Dickson,  S.  H.,  Passed  Assistant  Surgeon.  Frona 
Arctic  Squadron,  July  29th.    Sick  leave  August  30, 1884. 

pCjedijcal  Stems. 

Contagious  Dissasbs — ^Wkbkly  Statkusnt. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  September  6,  1884 : 


Week  Ending 


Outs, 
August  30,  1884 . . 
September  6, 1884 

August  30,  1884. . 
September  6,  1884 


4 

2 


I 


I 


Famous  Examples  of  Nervous  Exhaustion. — Much 
of  the  world's  best  work  has  been  done  by  neurasthenics, 
says  Beard.  George  Eliot,  Darwin,  Heine,  Spencer, 
Edwards,  Kant,  Bacon,  Montaigne,  Joubert,  Rousseau, 
Schiller,  illustrate  the  possibility  of  not  only  living,  but  of 
doing  original  work  on  a  small  capital  of  reser\'e  force. 


3o3 


THE  MEDICAL  RECORD. 


[September  13,  1884. 


The  American  Laryngological  Association  Viewed 
PROM  THE  Outside. — ^The  Burlington  Hawkey e^  in  no- 
ticing the  holding  of  the  sixth  annual  Congress  of  the 
American  Laryngological  Association,  takes  occasion  to 
thus  enlighten  the  lay  public  as  to  the  nature  of  that  body 
and  its  functions:  '*A  laryngological  association,  my 
dear,  is,  we  take  it,  an  association  of  larynxes.  And  a 
larynx  is — well,  it  is  the  active  principle  of  yoinr  'Adam's 
apple  ; '  the  lar3mx  lives  in  your  neck,  third  floor  front, 
between  the  tongue  and  the  trachea ;  it  has  nine  carti- 
lages, and  looks  like  an  old  garden  hose%gone  to  seed. 
And  its  uses  are — well,  you  know  when  a  little  mouse 
runs  across  the  floor  ?  Well,  your  larynx  is  what  you 
use  then.  '  Climb  on  the  table  with  it  ?  '  Great  Scot- 
land, no!  Who  ever  heard  of  climbing  up  on  a  table 
with  your  larynx  ?  No,  girl ;  you  *  holler '  with  it 
Thaf  s  what  you  do  with  it,  and  no  foolishness  about  it, 
either.  And  this  American  Laryngological  Congress,  we 
suppose,  is  organized  to  devise  some  means  whereby  to 
supply  a  new  India-rubber,  copper-lined  larynx  for  the 
star-eyed  goddess  of  reform,  she  having  shrieked  hers 
wide  open  and  split  it  down  the  back  when  Morrison 
fell." 

Chloroform  in  the  Treatment  of  Tape-worm. — 
Dr.  Henry  K.  Gardiner,  of  Providence,  R.  I.,  writes  : 
"  In  Vol.  26,  No.  4,  Medical  Record,  Dr.  J.  G.  Brooks 
reports  several  cases  of  tape -worm  treated  by  chloroform, 
and  claims  excellent  results.  Having  a  case  which  I  had 
previously  treated  unsuccessfully,  I  prescribed  the  fol- 
lowing: 9.  Chloroform,  3  j.;  muc.  acaciae,  5  iij.  M.  Sig, 
All  to  be  taken  at  once  after  twenty-four  hours'  fasting, 
to  be  followed  in  thirty  minutes  by  two  drops  of  croton 
oil  mixed  with  bread  crumbs.  It  produced  complete  an- 
aesthesia of  the  patient  in  two  or  three  minutes,  the 
efifects  lasting  ten  minutes;  and  for  some  hours  after 
headache  and  drunkenness  were  complained  of.  The  ol. 
tiglii  was  given  an  hour  after  taking  the  chloroform,  and 
tape-worm  expelled  entire  in  about  twenty  minutes.  I 
should  like  to  hear  of  other  cases  where  the  action  of 
chloroform  was  similar,'* 

Internal  Use  of  Nitrfte  of  AurvL. — Dr.  J.  F. 
Dixon  writes  to  ih^  British  Medical  Journal:  "There 
is  only  slight  mention  in  the  text-books,  and  scarcely 
any  reference  in  periodical  literature  to  the  internal  use 
of  nitrite  of  amyl.  Its  very  temporary  and  ephemeral 
action  when  inhaled  has  plainly  caused  therapeutists  to 
cast  about  for  an  agent  which  produces  more  continuous 
results.  I  believe  that  in  nitrite  of  amyl  given  internally 
we  have  a  drug  which  meets  all  the  requirements  of 
cases  in  which  it  is  important  to  lower  the  arterial  ten- 
sion ;  and  further,  that  it  is  free  from  the  uncertainty  of 
action  and  the  sometimes  dangerous  results  of  nitro- 
glycerine and  nitrite  of  sodium,  which  have  been  em- 
ployed apparently  as  substitutes  for  it.  I  have  employed 
it  thus  in  cases  of  anginous  attacks  of  a  very  severe 
character.  One,  complicated  with  very  loud  mitral 
systolic  murmur  and  nightly  angina  ;  the  second  with  an 
aortic  systolic  murmur,  and  the  third  with  irritable 
action,  but  no  apparent  organic  lesion.  I  may  say,  with- 
out going  into  particulars,  for  this  purports  to  be  the 
merest  sketch,  that  in  all  these  cases  the  relief  was  of  a 
marked  and  abiding  character.  The  dose  I  employed 
was  2^  minims  three  times  in  twenty-four  hours— of 
course,  seeing  the  case  twice  daily  until  the  action  of  the 
drug  was  established,  when  a  dose  each  night  was  suf- 
ficient 

Dissensions  in  the  Baltimore  Medical  Col- 
lege.— For  some  months  past,  says  the  Maryland  Medi- 
cal Journal^  rumors  have  been  afloat  of  inharmonious 
proceedings  in  the  Faculty  of  the  Baltimore  Medical 
College.  We  now  learn  that  these  have  gone  so  far  as 
to  result  in  a  division,  and  there  are  now  two  faculties, 
each  claiming  to  be  the  rightful  Baltimore  Medical  Col- 
lege. One  faction,  headed  by  Dr.  Bryd,  has  secured  a 
building  in  the  eastern  section  of  the  city,  while  the 


Munroe  party  is  entrenched  in  one  in  the  DGnrthem  part 
of  the  city.  Each  has  issued  a  catalogue,  and  matten 
are  rapidly  coming  to  a  crisis.  An  early  suit,  to  de- 
termine who  is  legally  entitled  to  the  rights  and  franchises 
conferred  by  the  charter,  is  foreshadowed. 

Cerebral  Congestion  during  Mental  Work.— Mr. 
Beecher  once  told  the  late  Dr.  Beard  that  after  preaching 
his  head  and  neck  are  sometimes  so  surcharged  with 
blood  that  a  large  seventeen-inch  collar  is  very  tight  for 
him,  but  in  an  hour  or  two  the  circulation  is  restored  and 
no  harm  results. 

Quinine  Diminishes  Sweating  after  work  upon  a  hot 
summer  day,  according  to  Liebermeister  and  Kemer. 

That  Florida  Climate. — Mens  conscia  recti  is  not 
much  disturbed  by  slander.  We  continue  to  receive 
earnest  protests  from  Gainesville  physicians  regarding  the 
views  on  the  climate  of  Florida  promulgated  by  Dr.  Boy- 
land.  We  had  every  reason  to  believe  that  the  views 
expressed  were  essentially  correct,  nor  do  we  think  that 
in  a  calm  discussion  it  would,  be  found  that  he  differed 
very  much  from  the  local  physicians.  Florida  is  an  ex- 
cellent place  for  many  cases  of  incipient  phthisis  ;  but  it 
does  not  benefit  all  cases.  On  the  other  hand,  the  cli- 
mate is  often  of  the  greatest  benefit  in  nervous,  catarrhal, 
and  rheumatic  troubles.  This  is  the  substance  of  the 
matter.  Per  contra^  Florida  is  not  always  Paradise.  It 
has  no  cataracts,  no  rushing  streams,  and  its  most  ad- 
nairing  residents  refer  to  mounds  of  earth  sixty  feet  high 
as  hills.  It  will  be  difficult  to  prove,  therefore,  that  its 
topography  is  admirably  adapted  for  drainage.  How- 
ever, we  have  not  the  slightest  desire  to  do  injustice  to 
the  State  or  any  part  of  it.  We  therefore  publish  a 
portion  of  an  account  by  Dr.  N.  D.  Phillips,  of  the  topog- 
raphy of  Gainesville,  and  with  this  we  must  close  the 
discussion.  Dr.  Phillips  says :  *'  There  is  a  never-failing 
stream  of  limpid  water  running  through  the  town  from 
north  to  south,  which  stream  separates  Gainesville  from 
East  Gainesville.  From  the  point  where  said  stream 
enters  the  northern  boundary,  to  where  it  crosses  the 
southern  boundary  of  the  town,  there  is  a  fall  of  forty- 
seven  feet  The  bed  of  this  stream,  due  east  of  the  pub- 
lic square,  is  thirty-five  feet  below  the  general  level  of 
the  town  on  either  side,  and  grows  deeper  as  it  mean- 
ders among  the  hills  on  its  way  to  Alachua  Lake,  eighty- 
six  feet  below  the  centre  of  Gainesville.  Due  west  of 
the  public  square  about  four  hundred  yards,  is  the  head 
of  a  deep  ravine,  also  running  south,  with  precipitous 
banks,  fed  by  never-failing  springs  of  pure  water.  The 
fall  in  the  bed  of  this  stream  is  greater  than  in  that  of 
the  stream  just  mentioned."  Another  stream  is  described 
arising  near  the  town  and  emptying  into  Canapaha  Lake. 
''  Alachua  and  Canapaha  Lakes  both  have  subterranean 
outlets,  which  outlets  are  sufficient,  although  the  lakes 
are  fed  by  numerous  springs  and  bold  streams,  to  pre- 
vent them  from  overflowing  their  banks,  even  in  the  wet- 
test seasons."  With  reference  to  the  "  stagnant  water  of 
which  the  doctor  speaks,  it  is  only  necessary  to  state  that 
tons  of  the  finest  fish  are  caught  from  Alachua  Lake  an- 
nually and  shipped  to  cities  north  of  this,  and  a  great 
deal  of  money  realized  from  the  business."  We  are  told 
that  since  the  leading  hotel  was  built,  in  1876,  only  eight 
deaths  have  occurred  within  its  walls.  Gainesville  is  213 
feet  above  the  St.  John's  River  at  Palatka,  and  Zd  feet 
above  Alachua  Lake. 

The  Forceps  in  Breech  Presentations. — Dr.  J.  H. 
Fruitnight,  of  this  city,  writes  :  '*  In  connection  with  the 
short  notice  of  *  The  Forceps  in  Breech  Presentations,' 
on  page  192  of  your  valuable  journal  of  the  issue  of 
August  1 6th,  let  me  direct  your  attention  to  a  paper 
written  by  me  on  that  subject  and  published  so  long  ago 
as  July,  1877,  in  the  Virginia  Medical  Monthly,  page 
246,  and  which,  so  far  as  I  know,  is  one  of  the  first 
articles  advocating  such  use  of  forceps." 


The   Medical   Record 

A   Weekly  Journal  of  Medicine  and  Surgery 


VoL  26,  No.  za 


New  York,  September  20,  1884 


Whole  No.  724 


Chriginal  l^trticljes. - 


THE  RECTUM  CONSIDERED  AS  A  RECEPTA- 
CLE FOR  THE  GRADUAL  ACCUMULATION 
AND  RETENTION  OF  THE  EXCREMENTAL 
MATTER. 

ByWILUAM  BODENHAMER,  A.M.»  M.D., 

NBW  YOBX. 

Owing  to  the  recent  attempts  of  some  authors  to  sus- 
tain with  new  arguments  the  theory  of  Mr.  O'Beirne, 
that  '*  the  rectum  is  not  a  receptacle  for  the  fecal  matter, 
neither  was  it  ever  so  designed,**  I  feel  disposed  to  offer 
some  arguments  in  favor  of  upholding  the  opposite 
theory.  The  late  talented  Dr.  Bushe,  many  years  ago, 
made  a  very  able  argument  against  the  theory  of  Mr. 
(yBeime.'  It  will  be  perceived,  however,  that  the  line 
of  my  argument  differs  materially  in  several  respects  from 
that  of  Dr.  Bushe. 

As  a  preliminary  to  the  investigation  of  this  subject, 
it  is  necessary  to  consider  briefly  the  form,  position,  di- 
rection, dimension,  and  structure  of  the  rectum,  as  well 
as  the  effect  of  that  structure  upon  the  accumulation  of 
fecal  matter  in  its  cavity. 

The  form  of  the  rectum  at  its  commencement,  like 
that  of  the  sigmoid  flexure  of  the  colon,  with  which  it  is 
continuous,  is  cylindrical,  and  it  maintains  this  form 
throughout  a  considerable  portion  of  its  extent;  but 
toward  its  inferior  extremity  it  becomes  large  and  sac- 
cated,  forming  a  terminal  pouch,  which  is  dilated  from 
before  backward  and  the  mouth  of  which  is  closed  by 
the  internal  sphincter  muscle,  like  a  purse.  This  dilata^ 
tion,  or  ampulla,  in  consequence  of  the  peculiar  organ- 
ization of  the  parts,  is  capable  of  acquiring  great  size, 
and  in  some  instances  of  long-continued  retention  of 
Heces  it  has  been  found  to  occupy  a  very  large  portion 
ot  the  cavity  of  the  pelvis. 

The  structure  of  the  rectum,  like  that  of  other  hollow 
viscera  of  the  abdomen,  is  composed  of  three  regular 
tanics — ^a  serous  or  peritoneal^  a  muscular ^  and  a  mucous 
—which  arc  intimately  blended  and  united  to  each  other 
by  cellular  tissue.  This  connective  tissue  has  been  dis- 
tinguished by  some  anatomists  as  an  additional  coat  of 
the  rectum,  thus  making  this  organ  to  consist  of  four 
tunics,  instead  of  three,  and  which  tissue  they  have 
severally  denominated  cellular^  submucous,  and  nervous. 
Be  this,  however,  as  it  may,  it  nevertheless  is  most  cer- 
tainly the  connective  tissue  between  the  peritoneal  and 
muscular,  and  between  this  last  and  the  mucous  coat, 
and  may  be  regarded  as  constituting  the  framework  of 
the  rectum. 

As  regards  the  structure  of  the  rectum,  its  several 
coats  are  gifted  with  peculiar  functions  in  health,  and 
when  under  the  influence  of  disease  each  is  subjected 
to  peculiar  affections.  The  muscular  coat  of  the  rectum 
especially  possesses  great  interest,  for  in  this  coat  resides 
Us  contractile  power,  and  to  this  coat  is  it  indebted  for 
its  properties,  both  as  a  retentive  and  as  an  expulsive 
organ.  The  muscular  coat  is  composed  of  longitudinal 
and  of  circular  flbres,  the  disposition  or  distribution  of 
which' merits  the  careful  study  of  the  physiologist.  The 
peculiar  arrangement  of  the  longitudinal  and  circular 

*  ATceatite  on  tbe  Malformadons,  Injuries,  and  Diseaaet  of  the  Rectum  and 
Abm,  p.  as  et  s«q.  8vo.   New  York,  1837. 


fibres  of  the  rectum,  which  differs  essentially  from  that 
of  any  other  portion  of  the  intestinal  canal,  has  furnished 
this  organ  with  the  power,  to  a  certain  extent,  of  retain- 
ing and  controlling  its  contents.  The  longitudinal  fibres 
are  much  larger  and  stronger  in  the  superior  portion  of 
the  rectum,  especially  anteriorly  and  posteriorly,  and 
they  become  smaller  and  weaker  as  they  approach  the 
internal  sphincter  ani.  By  this  change  or  alteration  in 
the  arrangement  of  these  fibres  the  rectum  is  enabled, 
in  its  inferior  portion  or  pouch,  to  retain  a  larger  quantity 
of  fecal  matter.  The  circular  fibres,  on  the  contrary, 
are  smaller,  fewer  in  number,  and  more  feeble  in  the 
superior  portion  of  the  rectum  where  they  are  less 
needed  and  where  the  action  of  the  abdominal  muscles 
is  alone  sufficient  to  propel  the  contents  of  this  intestine 
downward.  As  the  circular  fibres,  however,  approach 
the  inferior  portion  of  the  rectum,  they  are  more  numer- 
ous and  strong  where  they  are  most  needed,  and  are 
finally  blended  and  constitute  the  internal  sphincter  am. 
The  force  exerted  by  the  abdominal  muscles  in  the  act 
of  defecation  is  chiefly  expended  upon  the  superior  part 
of  the  rectum,  where  the  antagonists,  the  circular  fibres, 
are  weakest,  and  it  is  exactly  in  the  same  ratio  in  which 
this  force  diminishes  in  the  inferior  portion  of  the  rectum 
that  the  contractile  power  of  the  circular  fibres  in  this 
situation  increases.  These  are  facts  which  cannot  be 
controverted  and  must  not  be  ignored  in  the  considera- 
tion of  this  subject. 

The  mucous  coat  of  the  rectum,  from  its  peculiar 
structure,  is  well  adapted  for  the  passage  over  it  of  ex- 
traneous bodies.  It  is  studded  with  numerous  mucous 
glands  or  follicles,  from  which  are  derived  the  mucilagi- 
nous fluid  which  so  abundantly  lubricates  its  interior 
surface,  so  as  to  facilitate  the  passage  of  the  faeces  and 
at  the  same  time  to  protect  itself  firom  mechanical  vio- 
lence. Without  this  secretion  of  mucous,  or  sonoe  such 
lubricating  substance,  it  would  be  almost  impossible  for 
the  faeces  to  be  expelled. 

The  rectum,  therefore,  being  composed  of  membran- 
ous and  muscular  tissue,  is  by  the  first  well  fitted  both  to 
yield  and  to  expand  to  a  gradual  and  gentle  distending 
force,  so  as  to  form  a  perfect  recipient  reservoir  for  fecal 
matter ;  while  the  contractile  power  of  the  latter  is  well 
fitted  to  obliterate  the  cavity  of  the  organ  and  forcibly 
eject  its  contents.  This  musculo-membranous  viscus, 
then,  demands  attention,  not  only  as  to  its  structure,  but 
also  as  regards  its  situation,  form,  direction,  relations, 
and  connections.  The  form  and  direction  of  the  rectum, 
as  well  as  the  structure  of  its  several  coats,  and  its  pecu- 
liar muscular  equipment  as  a  receptive,  retentive,  and 
expulsive  organ,  display  a  most  admirable  provision  of 
nature  to  enable  it  to  perform  its  numerous  offices ;  in- 
deed, its  entire  anatomical  arrangement  evinces  a  design 
far  beyond  human  ingenuity. 

The  utility  of  the  direction  of  the  rectum  will  at  once 
appear  evident  when  we  take  into  consideration  that  had 
this  organ  been  straight,  as  its  name  implies,  we  should 
have  been  constantly  subjected  to  the  unpleasant  annoy- 
ance, especially  when  in  the  erect  posture,  of  a  dispo- 
sition to  empty  it ;  its  peculiar  direction  and  formation, 
however,  happily  protect  us  against  this ;  and,  further- 
more, the  pouch  located  at  its  inferior  extremity,  allow- 
ing a  large  accumulation  of  fecal  matter  to  collect, 
gives  sufficient  time  to  the  absorbents  of  the  part  to  take 
up  any  nutritive  particles  that  might  still  remain  in  the 
fecal  mass.     Precisely  the  same  kind  of  ampulla  or  en- 


3IO 


THE  MEDICAL  RECORD. 


[September  20,  18 


largement  obtains  in  all  canals  of  this  character,  at  such 
parts  of  them  as  have  normal  contractions  below  them. 
In  this  instance  the  anal  sphincters  are  the  contractors 
or  constrictors  and  form  the  impediment  to  the  further 
progress  of  the  fecal  matter  for  the  time  being. 

I  would  further  remark,  with  regard  to  the  pouch  of 
the  rectum,  that  Mr.  CoUes  says,  that  '^  it  is  much  more 
evident  in  adults  than  in  children  ;  however,  it  will  be 
found  in  children,  except  in  those  of  one  or  two  years."  * 
Some  years  ago  I  examined,  post  mortem^  the  rectum  in 
several  children,  their  ages  varying  from  six  to  eighteen 
months,  and  in  each  case  I  found  the  rectum  of  nearly  the 
same  diameter  throughout  its  entire  length.  No  dilata- 
tion could  be  observed  toward  its  inferior  extremity  in 
any  one  of  these  subjects.  This  pouch  evidently  does 
not  exist  in  early  infancy,  but  is  subsequently  gradually 
developed,  and  is  doubtless  the  result  of  distention, 
caused  finally  by  the  retention  and  accumulation  of  the 
faeces.  This  begins  to  take  place  as  the  act  of  defecation 
comes  under  the  influence  of  the  will ;  for  then  it  is  that 
the  dejections  become  much  less  frequent,  the  faeces  in- 
crease both  in  quantity  and  in  consistency,  and  are  suf- 
fered to  accumulate  for  a  length  of  time,  or  until  they 
provoke  by  their  presence,  perhaps,  the  expulsive  move- 
ment. In  early  life  defecation  is  chiefly  reflex,  but  it 
gradually  becomes  voluntary  by  habit.  In  children  the 
fecal  dejections  take  place  more  frequently  than  in 
adults,  being  usually  in  proportion  to  the  number  of 
meals.  This  frequency  is  doubtless  owing  to  the  diges- 
tion of  children  being  much  more  rapid,  the  intestinal 
secretions  more  profuse,  the  faeces  much  more  fluid,  and 
the  sensibility  of  the  alimentary  canal  much  greater. 
It  may  also  in  a  great  degree  depend  upon  the  fact  that 
in  childhood  the  rectum,  as  before  observed,  is  wholly 
uninfluenced  by  the  will. 

To  the  rectum,  then,  of  the  adult,  and  especially  to  its 
capacious  pouch,  belongs  the  office  of  reception,  accu- 
mulation, and  retention  of  the  fecal  matter ;  while  to  the 
anal  sphincters,  like  sentinels,  belongs  the  oflice  of  op- 
posing its  exit  for  the  time  being,  and  finally  of  giving 
permission  and  of  aiding  in  its  expulsion.  The  rec- 
tum, therefore,  may  with  great  propriety  be  denominated 
the  terminal  depdt  of  the  alimentary  canal.  Indeed,  it 
is  the  natural  dei>ository  of  the  excrementitious  matter 
just  previous  to  its  final  exit  from  the  body,  except  the 
parts  are  under  the  influence  of  certain  diseases,  such 
as  dysentery,  diarrhoea,  etc.,  when  the  faeces  will  not  be 
tolerated  in  the  organ  for  a  moment,  but  will  be  expelled 
as  soon  as  the  smallest  portion  presents  itself  in  it. 

It  must  now  be  observed,  however,  that  the  very  able 
and  distinguished  physiologist,  Mr.  O'Beirne,  of  Dublin, 
in  1833,  as  is  well  known,  positively  denied  that  the  rec- 
tum was  a  depdt  or  receptacle  for  the  temporary  lodg- 
ment of  the  faeces.  He  maintained  that  the  sigmoid 
flexure  of  the  colon  was  the  chief  receptacle  for  the  fecal 
matter  while  accumulating  in  quantity  suflicient  to  furnish 
a  proper  stool ;  that  in  health  the  pouch  of  the  rectum 
was  always  empty  of  faeces,  except  immediately  before  an 
evacuation  ;  and  that  the  upper  part  of  the  rectum  in- 
tervening between  the  colon  and  rectal  pouch  was  not 
only  always  empty  but  firmly  contracted  by  the  circular 
muscular  fibres.' 

Now,  according  to  Mr.  0*Beirne,  the  sigmoid  flexure 
of  the  colon  is  the  chief  dep6t  for  the  deposit  and 
retention  of  the  alvine  excretions,  while  the  rectum  is 
the  mere  avenue  for  the  transmission  of  such,  or  the  mere 
faucet  or  funnel  through  which  such  are  rapidly  passed 
out  of  the  body  when  called  into  requisition  by  the  sig- 
moid flexure.  Hence  there  is  no  necessity,  according  to 
Mr.  O'Beirne,  for  the  rectal  pouch,  nor  for  the  anal 
sphincters  below  it,  which  guard  it,  inasmuch  as  his 
colonic  pouch  or  receptacle  is  guarded  by  the  superior 
portion  of  the  rectum,  which  he  says  is  always  firmly  con- 
tracted and  acts  as  a  sphincter,  and  consequently  that 

^  A  Treatise  on  Surjcical  Anatomy^  p.  137.  8vo.    Philadelphia,  1831. 

-  New  Views  of  the  Process  of  Defecation,  p.  3  et  seq.    8vo.  1  DuUin,  1833. 


the  power  of  retaining  and  controlling  the  fecal  discharge 
does  not  depend  upon  the  anal  sphincters. 

I,  however,  hold  that  the  colon  and  rectum  are  one 
continuous  canal,  and  their  junction  is  not  provided  with 
a  sphincter  muscle,  such  as  are  the  anal  sphincters.  Iq. 
deed,  Mr.  O'Beirne,  feeling  the  absolute  necessity  of  a 
recto-colonic  sphincter  to  protect  his  theory  and  his 
colonic  pouch,  endeavors  to  prove  that  the  whole  of  the 
superior  portion  of  the  rectum  acts  in  the  capacity  of 
such  a  sphincter  muscle.  I,  on  the  contrary,  however, 
positively  maintain  that  the  superior  portion  of  the  rectum 
is  not  any  more  firmly  contracted  than  any  other  portion 
of  the  intestinal  canal  not  supplied  with  a  sphincter  or 
sphincters,  as  any  expert  can  at  once  verify  by  the  proper 
exploration.  It  is  true  the  faeces  are  retarded,  and  con- 
sequently  detained  longer  in  passing  through  the  coiled 
portion  of  the  colon,  but  this  detention  there  is  not 
owing  to  any  sphincter  or  sphincters,  but  is  obviously 
owing  to  the  peculiar  form,  direction,  and  position  of  the 
sigmoid  flexure.  It  may  be  admitted  that  the  faeces  in 
the  coiled  portion  of  the  colon,  as  in  the  caecum,  are  for 
obvious  reasons  detained  longer  in  passing  these  points 
than  they  are  in  passing  other  parts  of  the  colon,  but 
this  fact  alone  does  by  no  means  constitute  these  por- 
tions of  the  colon  reservoirs  for  the  accumulation  of  the 
faeces,  as  some  authors  claim,  to  the  exclusion  of  the  ] 
rectum  as  such. 

With  regard  to  the  very  plausible  and  ingenious  theory, 
so  ably  presented  by  Mr.  O'Beirne,  I  respectfully  beg 
leave  to  differ  from  it  in  several  respects  ;  for  instance, 
instead  of  the  healthy  rectum  being  always  empty  be- 
tween the  periods  of  defecation,  as  he  contends,  I  am  of 
opinion  that  it  is  never  entirely  so.  I  hold  that  even 
immediately  after  a  natural  evacuation  of  the  rectum 
there  is  still  more  or  less  consistent  excrement  left  in  the 
superior  portion  of  it ;  indeed,  it  is  more  in  the  character  1 
of  a  displacement  merely  of  the  fecal  matter  of  the  in- 
ferior portion  of  the  rectum,  in  the  ordinary  calls  of 
nature  in  healthy  persons,  than  by  a  complete  evacuation 
of  the  whole  contents  of  the  organ  ;  for  it  must  be  ob- 
served that  besides  the  contractile  power  of  this  part  of 
the  rectum  itself  the  vis  d  tergo  of  the  consistent  natural 
excrement  also  powerfully  aids  in  effecting  a  dislo<1g- 
ment  or  stool.  When  the  rectum  is  completely  emptied 
by  an  active  cathartic,  or  a  stimulating  enema,  or  as  in 
some  diseases,  such  as  dysentery,  diarrhoea,  the  vis  d 
tergo  is  for  a  time  absent,  and  in  a  person  of  good 
health  it  requires  from  two  to  three  days  to  re-establish 
it,  by  the  rectum  becoming  moderately  repleted  again 
and  so  making  provision  for  this  part  of  the  natural 
mechanism  by  which  the  consistent  fecal  matter  is  ordi- 
narily discharged.  The  rectum,  then,  which  was  designed  i 
by  nature  to  serve  the  place  of  a  reservoir,  is  never 
entirely  empty  when  in  its  normal  and  healthy  state,  but 
always  contains  some  fecal  matter  in  some  portion  of  it, 
and  it  is  the  inferior  portion  only  that  is  generally  evac- 
uated when  naturally  called  to  perform  this  act. 

In  the  exercise  of  my  profession,  during  a  practice  of 
many  years,  I  have  examined  the  rectum  in  numerous 
instances,  some  with  special  reference  to  this  very  ques- 
tion, and  I  have  scarcely  ever  failed  to  discover  more  or 
less  fecal  matter  in  some  part  of  the  organ.  If  the 
rectum  is  examined  twenty-four  hours  after  an  evacua- 
tion, the  fecal  accumulation  during  that  period  will 
generally  be  found  lodged  a  little  beyond  the  superior 
margin  of  the  internal  sphincter,  about  four  inches  above 
the  verge  of  the  anus.  With  this  intention  1  have  ex- 
amined the  rectum  in  the  same  individual  as  often  as  two 
or  three  times  in  the  twenty  hours  ;  and  for  thb  purpose 
I  use  a  bivalve  speculum  ani,  introduce  it  fairly  above  the 
internal  sphincter,  open  it  sufliciently,  and  then,  through 
the  open  blades  of  this  instrument,  pass  up  a  No.  2  or  3 
English  rectal  bougie  to  the  superior  end  of  the  rectum 
and  withdraw  it,  and  if  it  has  come  in  contact  with  fecal 
matter  some  of  it  will  adhere  to  the  bougie  and  can  be 
plainly  perceived.     In  some  instances  I  have  found  that 


September  20,  1884.  J 


THE  MEDICAL  RECORD. 


3" 


the  bougie  could  scarcely  be  pushed  up  through  the 
column  of  solid  excrement,  which  had  evidently  been 
lodged  in  the  rectum  for  many  hours.  This  condition  of 
the  solid  excrement  found  in  the  rectum  I  have  observed 
to  be  more  common  in  females  than  in  males.  This, 
however,  is  said  not  to  be  the  experience  of  gynecolo- 
gists generally,  who  now,  more  than  ever  before,  very 
properly  make  use  of  the  rectum  for  diagnostic  purposes. 
But  I  by  no  means  agree  with  the  author,  who  says  that 
<< gynecologists  by  their  daily  examinations  in  the  vagina 
are  quite  familiar  with  the  fact  that  the  rectums,  even  of 
women  of  torpid  habits,  are  comparatively  seldom  found 
loaded  with  faces,  but  empty  and  flattened  between  the 
^'agina  and  the  sacrum.''  I  have  found  that  if  the  exami- 
nation of  the  rectum  be  made  just  before  the  usual  daily 
evacuation  the  fecal  mass  may  often  be  detected,  even 
bj  the  finger,  in  ano. 

In  the  dead  body  I  have  never  found  the  rectum  to 
be  entirely  empty,  and  it  may  be  observed  that  in  ana- 
tomical examinations  healthy  excrement  is  just  as  often 
found  in  the  rectum  as  in  the  sigmoid  flexure  of  the 
colon;  indeed,  it  is  sometimes  found  collected  in  the 
caput  coli,  which  has  been  considered  by  some  as  a  fecal 
receptacle,  and  sometimes  found  at  an  intermediate  point. 
This,  it  appears  to  me,  must  be  the  experience  of  every 
one  who  has  had  frequent  opportunities  of  examining 
these  organs  ia  the  cadaver, 

Mr.  O'Beirne,  in  accordance  with  his  theory,  has  been 
compelled  to  assume  as  probable  phenomena  which 
do  not  admit  of  positive  or  demonstrative  proof ;  for  ex- 
ample, his  conception  of  the  manner  in  which  the  faeces 
are  unloaded  from  or  emptied  out  of  the  sigmoid  flexure 
into  the  rectum  is,  in  my  opinion,  purely  hypothetical.  I 
dierefore  believe  that  some  of  his  views  on  this  subject 
are  theoretically  wrong.  I  wish  particularly  to  mention 
here  that  the  healthy  faeces  do  not  pass  out  of  the  coiled 
portion  of  the  colon  into  the  rectum  continuously,  for 
they,  like  in  other  portions  of  the  intestines,  are  not  per- 
petually in  motion,  but  their  movement  is  intermittent. 
They  neither  pass  out  of  the  sigmoid  flexure  at  once  in 
bulk  suflicient  for  one  ordinary  stool,  the  result  of  one 
da/s  accumulation,  as  Mr.  O'Beirne  declares,  but  pass 
into  the  rectum  at  intervals  in  small  portions,  each  por- 
tion being  the  fecal  residue  of  but  one  meal  of  the  solid 
ingesta  of  the  stomach.  As  each  successive  portion  is 
received  in  the  superior  part  of  the  rectum,  the  former 
one  is  propelled  forward  by  the  impulse  given  it  from 
behind,  assisted  by  the  contractile  or  vermicular  power 
of  the  part  itself,  until  it  eventually  arrives  at  the  inferior 
part  of  the  rectum,  where  it  and  the  portions  that  follow 
in  the  same  manner  slowly  accumulate,  assume  shape 
and  figure,  and  gradually  and  gently  distend  the  organ. 
As  a  general  rule  the  excrementitial  residue  of  one  day's 
aliment  taken  into  the  stomach  and  amassed  in  the  rec- 
tam  is  considered  sufficient  to  provoke  the  expulsory 
movement. 

Mr.  O'Beirne  bein^  continually  confronted  by  the  fact 
that  between  the  periods  of  defecation  faeces  were  found 
in  the  rectum,  which  he  had  declared  to  be  always  empty, 
was  compelled  to  notice  this,  to  him,  singular  circum- 
stance, and  to  account  for  it.  This  he  does  by  attribut- 
ing it  entirely  to  morbid  phenomena,  and  admitting  that 
by  such  even  the  rectum  itself  may  become  the  final 
reservoir  of  the  faeces  in  place  of  the  sigmoid  flexure.  He 
says  this  result  is  brought  about  when  the  whole  of  the 
rectnm,  together  with  the  sphincters,  is  rendered  para- 
lytic. He  is  very  safe  in  making  this  admission,  for  it  is 
well  known  that  injuries  of  the  brain  and  spinal  marrow 
may  and  do  result  in  paralysis,  not  only  of  the  rectum 
but  sometimes  of  the  coiled  portion  of  the  colon,  as  well  as 
other  portions  of  the  intestinal  canal — thus  converting 
such  portions,  for  obvious  reasons,  into  reservoirs,  or  stop- 
ping-places for  the  faeces.  In  compression  of  the  brain  the 
external  sphiacter  is  almost  entirely  disabled,  and  in  com- 
pression cf  the  cord  the  power  of  the  internal  sphincter  is 
also  impaired.     A  morbid  condition  of  the  rectum,  how- 


ever, in  a  modified  degree,  may  be  produced  by  atony  of  its 
walls,  and  perhaps  this  is  what  Mr.  O'Beirne  means  by  the 
use  of  the  word  paralytic^  that  is,  merely  debility  or  want 
of  tone.  The  rectum,  like  all  other  hollow  viscera,  may  be 
subjected  to  paralysis  from  injuries  of  the  brain  and  spi- 
nal marrow,  as  has  already  been  observed,  or  to  atony 
from  undue  distention  of  its  parietes  by  fecal  matter,  by 
gas,  or  by  both,  as  well  as  from  other  causes.  But  the 
question  here,  however,  is  not  what  the  rectum  may  be- 
come by  disease,  such  as  paralysis,  spasmodic  or  organic 
stricture,  atony,  etc.,  but  is  the  rectum  naturally  and  in 
health  a  receptacle  for  faeces  ?  That  is  the  question,  for 
it  must  be  understood  in  this  affair  that  whatever  is  said 
concerning  the  rectum  and  its  fiinctions  or  actions,  both 
directly  and  indirectly,  must  have  reference  only  to  its 
healthy  or  normal,  and  not  to  its  morbid  or  abnormal 
condition. 

One  of  the  recent  and  ardent  advocates  of  the  theory 
of  Mr.  O'Beirne,  after  first  declaring  that  the  sigmoid  flex- 
ure of  the  colon  is  the  proper  receptacle  for  the  faeces,  and 
that  the  rectum  was  never  designed  for  such  a  purpose, 
proceeds  to  account  for  the  puzzling  phenomenon  of 
finding  fecal  accumulations  in  the  rectum  between  the 
periods  of  defecation.  He  declares  that  whenever  faeces 
are  thus  found  lodged  in  the  rectum  it  is  entirely  owing 
to  atony  of  the  walls  of  this  organ,  by  which  it  is  inca* 
pacitated  or  indisposed  to  forward  on  through  it  at 
once,  without  stoppage,  the  contents  of  the  sigmoid 
flexure,  hence  faeces  are  permitted  to  accumulate  in  it. 
The  atony  of  the  rectum  is  brought  about,  says  he,  by 
the  repeated  neglect  of  the  calls  of  nature,  by  which  the 
rectum  is  gradually  educated  to  tolerate  that  which  is 
really  irritating  to  it,  and  it  is  only  the  educated  or  atonied 
rectum  that  ever  contains  faeces  between  the  periods  of 
defecation.*  The  argument  of  this  author,  like  that  of 
Mr.  O'Beirne,  is  that  the  rectum  in  its  healthy  state  is 
always  empty  between  the  periods  of  defecation;  and 
that  this  being  its  normal  condition  it  cannot,  therefore, 
be  a  natural  reservoir  for  fecal  accumulation;  but  by 
pernicious  education,  however,  which  he  explains,  this 
very  susceptible  or^an  may  be  taught  to  tolerate  in  its 
natural  empty,  sensitive,  and  contnicted  cavity,  the  pres- 
ence and  the  lodgment  of  fecal  matter ;  and  thus  finally 
become  that  which  was  not  designed  by  nature,  namely, 
an  artificial  depository  for  excrement  The  whole  argu- 
ment of  this  author  is  to  prove  that  the  rectum  can  be 
converted  artificially  into  a  fecal  receptacle  by  education, 
as  if  that  was  the  question  at  issue,  but  not  a  single  ar- 
gument does  he  give  to  prove  that  the  uneducated  rec- 
tum is  not  normally  such  a  receptacle.  This  it  be- 
hooved him  to  do  first,  and  afterward  to  account  for  the 
fact  of  fecal  matter  being  found  in  the  cavity  of  the  rec- 
tum. 

I  maintain  that  the  rectum  is.  naturally  the  terminal 
dep6t,  or  last  resting-place  for  the  healthy  excremental 
matter  previous  to  its  final  evacuation  from  the  body, 
and  that  it  tolerates  such  there  for  a  certain  period  with- 
out being  specially  educated  to  do  so,  for  that  is  its  nor- 
mal function.  This  is  proved  by  its  anatomical  structure, 
its  peculiar  nervous  endowment,  and  by  the  fact  that, 
more  or  less  healthy  excrement  will  always  be  found  in 
some  part  of  the  cavity  of  a  normal  and  sound  rectum. 
This,  indeed,  is  the  rule ;  the  reverse  of  this  is  the  excep- 
tion. It  is  true  that,  by  repeated  neglect  to  respond  to 
the  daily  calls  of  nature  to  empty  the  sound  rectum,  con- 
stipation, or  a  morbid  condition  of  its  parietes  is  sooner 
or  later  induced,  by  which  its  sensibility  is  blunted 
and  its  contractile  power  more  or  less  diminished,  this 
morbid  condition  being  of  course  greatly  aggravated  by 
the  repletion,  irritation,  and  excessive  distention  which 
follow  ;  so  that  the  rectum  ultimately  becomes  capable 
of  containing  and  tolerating  a  much  larger  quantity  of 
excrement  at  any  one  time  than  normal,  and  also  of  re- 
taining it  much  longer,  too,  without  the  natural  admoni- 

1  Philadelphia  Medical  Times  p.  sS^i  November  x8,  1882. 


312 


THE  MEDICAL  RECORD. 


[September  20,  1884. 


tion  to  move  it.  But  this  morbid  state  of  the  rectum, 
by  whatever  cause  produced,  is  no  evidence  whatever 
that  it  is  not  a  natural  receptacle  for  excrement,  previous 
to  such  morbid  condition  consequent  upon  artificial 
training. 

The  nisus  defacans^  or  sensation  for  the  evacuation  of 
the  faeces,  takes  place  in  the  rectum,  where  it  should,  and 
not  in  the  sigmoid  flexure  of  the  colon,  as  Mr.  O'Beime 
and  his  advocates  claim.  The  coiled  portion  of  the 
colon  is  not  under  the  influence  of  the  will  in  its  move- 
ments, but  is  entirely  governed  by  the  automatic  operations 
of  the  other  portions  of  the  intestines,  and  which  termi- 
nate at  the  inferior  portion  of  the  rectum,  which  portion 
we  know  is  under  the  direction  and  control  of  a  separate 
and  entirely  different  set  of  nerves.  It  is  doubtless  in 
this  portion  of  the  rectum  that  the  nisus  defacans  origi- 
nates, and  it  is  through  these  nerves  that  the  sensation  is 
communicated.  The  association  which  exists  between  the 
functions  of  these  different  nerves  is  brought  into  action 
periodically,  when  in  health,  by  the  distention  of  the 
walls  of  the  rectum  arriving  at  a  certain  stage.  This 
united  action,  from  various  causes,  as  I  have  already 
shown,  may  be  disturbed,  or  it  may  not  be  in  equipoise, 
and  artificial  means,  such  as  cathartics,  enemata,  or  stim- 
ulating applications  to  the  lining  membrane  of  the  or- 
gan, may  be  required  to  reproduce  the  suspended  co- 
operation. 

While  some  physiologists  are  of  opinion  that  the  un- 
easy sensation  which  arrests  the  attention  of  the  will  to 
the  act  of  defecation  resides  in  the  rectum,  there  are 
others,  however,  who  believe  that  it  does  not  take  place 
solely  in  that  organ,  but  is  often  seated  in  the  stomach, 
more  frequently  in  the  small  intestines,  and  sometimes 
only  in  the  imagination.  Mr.  O'Beime,  as  before  re- 
marked, is  of  opinion  that  it  originates  in  the  sigmoid 
flexure  of  the  colon.*  My  opinion  is  that  this  admoni- 
tion originates  in  the  rectum  alone,  the  natural  reservoir, 
in  a  normal  and  healthy  condition  of  all  the  parts  con- 
cerned, because  no  portion  of  the  intestinal  canal  is 
supplied  as  this  is  with  the  prop3r  nerves  to  communi- 
cate it.  When  it  is  experienced  in  the  stomach,  in  the 
small  intestines,  or  anywhere  else,  except  in  the  rectum,  it 
must  be  in  consequence  of  disease  of  the  stomach,  or  of 
such  portion  of  the  intestines,  or  of  the  brain  or  nervous  sys- 
tem. As  to  the  cause  of  this  admonition  there  are  various 
opinions.  Some  allege  that  it  is  induced  by  the  mechan- 
ical distention  of  the  parietes  of  the  rectum,  the  result  of 
accumulated  fecal  matter,  gas,  or  both,  and  I  am  of  this 
opinion  ;  others,  that  it  is  produced  by  the  mere  contact 
of  the  fecal  matter,  the  natural  stimulus  of  the  intestines, 
with  the  interior  surface  of  the  rectum ;  others,  again, 
that  it  is  caused  by  the  acrimony  of  the  faeces,  acquired 
by  their  retention  in  the  rectum.  The  truth,  however,  is 
that  the  cause  of  this  sensation  is  not  positively  known, 
consequently  all  in  relation  to  it  is  more  or  less  conjec- 
tural. Analogy  shows  that  nature  employs  a  somewhat 
similar  agency  in  the  case  of  other  hollow  viscera  pro- 
vided with  muscular  fibres,  as  the  bladder  and  the  uterus. 

Mr.  O'Beirne's  peculiar  neurological  views  on  this  sub- 
ject, his  ideas  on  the  peristaltic  motion  or  intestinal  ac- 
tion, etc.,  will  be  fully  considered  hereafter  in  a  separate 
article,  on  the  '*  Anatomy  and  Physiology  of  the  Sigmoid 
Flexure  of  the  Colon." 

949  Madison  Avbmub,  Nbw  Yokk. 


Verges. — Old  Dogberry's  fellow  officer  derived  his 
name  from  the  corruption  of  verjuice  into  verges.  Ver- 
juice is  verdjus,  or  the  juice  of  any  green  fruit,  such  as 
the  acid  liquor  expressed  from  wild  apples,  sour  grapes, 
etc. 

Sickness  and  Morals. — ''Every  man  is  a  rascal  as 
soon  as  he  is  sick,"  said  Dr.  Johnson. 

»  Op.  dt.,  p.  t8. 


ON  THE  TOLERANCE  OF  CORROSIVE  SUBLI- 
MATE IN  SMALL  AND  FREQUENT  DOSES. 

By  ANDREW  H.  SMITH,  M.D., 

NEW  YOWC. 

As  preliminary  to  the  more  extended  use  of  corrosive 
sublimate  as  an  anti-zymotic  or  anti-ferment,  it  is  impor- 
tant to  settle  the  question  of  the  safety  or  danger  of  ad- 
ministering it  in  such  quantities  as  may  reasonably  be 
expected  to  act  upon  the  mass  of  the  blood  in  such  man- 
ner as  to  destroy  a  poison  floating  in  the  circulation. 

The  dangers  to  be  apprehended  are,  first,  local  irrita- 
tion ;  second,  mercurial  poisoning. 

The  following  observations  will  help  to  form  an  esti- 
mate of  each  of  these  dangers.  It  may  be  premised  that 
in  no- case  was  the  degree  of  dilution  less  than  one  in 
ten  thousand.  The  first  eight  observations  were  at  the 
Presbyterian  Hospital  during  my  service,  and  for  the 
notes  I  am  indebted  to  the  kindness  of  the  house  physi- 
cian. Dr.  Charles  G.  Wagner. 

Cass  L — Annie  C ;  Irish;  married;  forty  years  of 

age;  admitted  April  21,  1884.  Disease,  phthisis  pul- 
monalis,  third  stage.  Patient  had  been  under  observa- 
tion three  weeks  when  mercurial  treatment  was  begun. 
Temperature  had  ranged  from  100.5°  ^o  *o3-5**« 

May  loth. — She  was  given  hydrarg.  bichlor.,  gr.  j^ 
every  hour  for  seven  hours.  Temperature  did  not  nse 
within  a  degree  as  high  as  on  the  previous  evening. 

May  nth. — Bichloride  continued  (largely  diluted), 
gr.  ^  every  hour  for  eight  hours.  Temperature  niearly 
two  degrees  lower  than  on  previous  night. 

May  1 2th. — Bichloride  continued.  Temperature  in 
rooming  was  normal.   In  the  evening  it  rose  only  to  100^. 

Treatment  was  continued,  and  the  case  remained  un- 
changed durin|(  next  three  days.  On  the  fourth,  patient 
had  bloody  diarrhoea,  and  the  bichloride  was  stopped 
Diarrhoea  lasted  but  one  day.  Treatment  was  not  re- 
sumed. 

Case  II. — Gertrude  M ;  Irish ;  single ;  domestic ; 

twenty-six  years  of  age;  admitted  February  17,1884. 
Disease,  chronic  diffuse  nephritis  with  mitral  regurgita- 
tion. Patient  had  been  under  observation  three  months 
when  hydrarg.  bichloride  treatment  was  begun.  She  had 
for  several  weeks  been  passing  a  very  small  amount  of 
urine. 

May  17th. — Patient  was  given  hydrarg.  bichlor.,  gr.  ^ 
every  two  hours  during  the  day  (none  at  night).  The 
immediate  efifect  apparently  was  to  increase  the  quantity 
of  urine.  She  continued  to  take  the  drug  for  four  days, 
when  she  had  bloody  diarrhoea,  but  no  pain  in  the  gums 
nor  any  salivation,  the  bichloride  was  suspended  and  the 
diarrhoea  ceased  after  six  or  seven  passages.  Treatment 
not  resumed. 

Case  III. — Patrick  McK ;  Irish;  single;  driver; 

forty-seven  years  of  age;  admitted  May  2,  1884.  Dis- 
ease, tertiary  syphilis,  pachymeningitis  (cephalalgia). 
Patient  was  put  immediately  on  hydrarg.  bichlor.,  gr.  ^ 
three  times  a  day,  with  potassii  iodidi,  gr.  xv.  t.Ld. 

May  15th. — He  was  put  on  hydrarg.  bichloride,  gr.  ^ 
every  hour  during  the  day  (not  in  the  nightjf.  Treatment 
continued  daily  until  May  20th,  when  patient  had  pain 
in  the  jaws,  and  gums  felt  sore,  no  marked  salivation. 
Hydrarg.  bichloride  stopped  ;  ordered,  K,C10,. 

Case  IV. — ^Julius  J ;  American ;  single ;  twent}'- 

one  years  of  age ;  admitted  April  26,  1884.  Disease, 
chronic  diffuse  nephritis.  Patient  had  been  under  obser- 
vation in  the  hospital  about  three  weeks ;  was  passing 
fifty  to  sixty  ounces  urine  a  day,  which  contained  albu- 
men and  casts. 

May  i8th. — He  was  put  on  hydrarg.  bichloride,  gr.  ^ 
every  hour.  This  was  continued  eight  days,  during  day- 
time, with  no  apparent  effect  on  any  of  the  functions. 
The  amount  was  then  reduced  to  gr.  ^  every  two  hours, 
which  he  continued  to  tolerate  until  June  3d,  when  it  was 
discontinued. 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


313 


Case  V.-— John  O'N ;  Irish  ;  married  ;  aged  fifty- 
five.     Admitted    March   23,  1884.      Disease,   chronic 

diffuse  nephritis. 

May  15  th. — Patient  was  put  on  hydrarg.  bichlor.,  gr. 
^  every  four  hours. 

May  20th. — Bichloride  increased  to  gr.  ^  every  two 
hours. 
May  27th. — Bichloride  stopped.     No  effects  noticed. 
Case  VI. — Daniel  H ;  nurse;  widower;  aged  forty- 
six;  admitted  May  7,  1884.     Disease,  facial  erysipelas. 

May  7th. — Hydrarg.  bichlor.  was  begun  on  May  loth ; 
dose,  gr.  -^  every  hour  during  daytime. 

May  1 2th. — Patient  complained  of  pain  in  gums  and 
profuse  salivation.  Hydrarg.  bichlor.  stopped.  Treat- 
ment not  resumed. 

Case   VII. — Dora   V ;  German;  married;  aged 

thirty-one;  admitted  March  31,  1884.  Disease,  phthisis 
polmonalis,  chronic  diarrhoea. 

May  2ist — ^Patient  was  given  hydrarg.  bichlor.,  gr.  ^ 
every  hour.  This  was  continued  until  May  23d  with  no 
obvious  effect.     It  was  then  discontinued. 

The  following  observations  were  made  in  private 
practice : 

Case  VIII. — Mrs.  H ;  puerperal  peri-metritis  with 

malarial  complication.  Bowels  constipated ;  -^  gr.  bi- 
chloride given  every  hour  for  eleven  hours,  then  ^  gr. 
every  hour  for  seven  hours.  Griping  pain  was  then  felt 
in  the  abdomen  and  three  liquid  evacuations  occurred  in 
rapid  succession.  Bichloride  stopped,  after  which  the 
diarrhoea  ceased  spontaneously.    No  stomatitis  occurred. 

Case   IX. — J.    B ,    aged   six    years.      Malignant 

measles  with  excessive  temperature,  ^  gr.  bichloride 
every  two  hours  for  three  days.  No  irritation  of  stomach 
or  bowels,  no  soreness  of  the  mouth.  The  urine,  which 
at  first  was  very  scanty,  was  increased  to  double  the 
normal  quantity.     It  contained  no  albumen. 

Case  X. — M.  S ,  six  and  one-half  years  of  age  ; 

diphtheria  following  scarlet  fever.  Patient  took  ^  gr. 
bichloride  hourly,  with  very  few  omissions,  day  and  night 
for  a  week,  and  the  same  quantity  during  the  day  with 
two  or  three  doses  during  the  night  for  several  suc- 
ceeding days.  Chlorate  of  potash  and  tincture  of  the 
chloride  of  iron  were  given  at  the  same  time.  The 
mouth  was  not  affected  and  there  was  little  or  no  irrita- 
tion of  the  stomach  or  bowels.  The  urine  was  increased 
to  seventy  ounces,  but  fell  to  the  normal  amount  when 
the  drug  was  discontinued.  It  did  not  contain  albumen 
during  this  time,  though  a  very  slight  albuminuria  was 
afterward  developed. 

Case  XL — Miss  H.  G ,  fifty  years  of  age,  con- 
tracted kidney  anasarca  of  legs ;  urine  much  decreased 
in  quantity,  but  of  high  specific  gravity,  no  nausea  or 
other  uraemic  symptoms.  One-twentieth  of  a  grain  in 
four  ounces  of  water  immediately  produced  gastric  dis- 
tress followed  by  vomiting.  A  second  dose  three  hours 
later  resulted  similarly,  and  the  patient  declined  to  pur- 
sue the  treatment  further. 

From  an  examination  of  these  histories  it  will  be  seen 
that  in  five  of  the  eleven  cases,  the  bichloride  given  in 
quantities  of  from  ^  to  ^  of  a  grain,  and  at  intervals  of 
one  or  two  hours,  produced  no  ill  effect.  Of  the  other 
six  cases  diarrhoea  with  griping  occurred  in  one,  bloody 
diarrhoea  in  two,  and  ptyalism  in  two. 

The  bloody  diarrhoea  occurred  in  one  case  after  seven 
hourly  doses  of  ^  grain  the  first  day,  and  eight  hourly 
doses  on  each  of  the  four  succeeding  days.  In  the  other 
case  the  drug  was  given  in  the  same  dose  but  at  intervals 
of  two  hours  throughout  the  day,  and  the  bloody  dis- 
charges occurred  after  four  days.  In  both  instances  the 
diarrhoea  ceased  immediately  on  the  withdrawal  of  the 
medicine. 

Stomatitis  occurred  in  one  case  after  five  days'  use  of 
the  bichloride  in  hourly  doses  (during  the  day)  of  ^ 
grain,  and  in  the  other  case  after  two  days. 

In  one  case  an  idiosyncrasy  caused  gastric  distress 
and  vomiting  immediately  upon   taking  ^  grain,  and 


this  recurred  when  the  dose  was  repeated  some  hours 
afterward. 

In  one  case  of  phthisical  diarrhoea  ^  grain  every  hour 
for  two  days  neither  increased  nor  diminished  the  diar- 
rhoea, producing  in  fact  no  obvious  effect. 

In  two  cases  of  children  under  seven  years  of  age 
doses  nearly  equal  to  those  given  to  adults  were  remark- 
ably well  tolerated. 

In  three  cases,  one  of  chronic  diffuse  nephritis,  one  of 
scarlet  fever  and  diphtheria,  and  one  of  measles,  the  drug 
produced  a  marked  diuretic  effect. 

In  one  case  of  phthisical  hectic  the  temperature  was 
apparently  reduced  in  a  marked  degree  by  the  bichloride. 


ON  THE  PREPARATION  AND  USE  OF  OXY- 
GEN AND  ITS  CONGENERS  AS  REMEDIAL 
AGENTS. 

By  SAMUEL  S.  WALLIAN,  A.M.,  M.D., 

BLOOMINGDALK,  N.  Y. 

(Continued  firom  page  9S7.) 

Methods  and  appliances  for  clinical  exhibition, — As 
will  be  inferred,  the  use  of  these  agents,  although  not 
necessarily  restricted  to  these,  is  more  especially  adapted 
to  office  and  hospital  practice.  For  a  complete  office 
equipment  in  every  considerable  practice  there  should 
be  at  least  three  separate  reservoirs.  One  should  contain, 
at  all  times,  pure  oxygen,  ready  for  instant  use  in  cases 
of  emergency ;  a  second  may  contain  pure  nitrogen 
monoxide,  and  a  third  such  modified  admixture  as  is 
found  best  adapted  to  the  class  of  cases  under  treat- 
ment One  or  more  additional  reservoirs  will  at  all 
times  be  found  a  matter  of  convenience,  and  in 
undertaking  the  treatment  of  a  variety  of  cases  in  an 
extensive  hospital  or  general  office  practice,  quite  essen- 
tial. These  should  be  arranged  so  as  to  be  readily 
connected  when  desired.  They  may  be  placed  in  a  suit- 
able hall,  closet,  or  private  room  adjoining  the  office, 
and  connected  with  the  latter  either  by  ordinary  gas-pipe 
or  by  rubber  tubing.  The  latter  may  be  neatly  covered 
with  rep  or  other  suitable  material,  as  a  matter  of  taste. 

The  mouth-piece  or  inhaler  may  be  of  glass  or  hard 
rubber,  and  it  is  to  be  connected  with  the  reservoir 
through  covered  rubber  tubing  and  a  glass  bell,  or  a 
small-sized  wash-bottle  half  filled  (with  simple  water,  a 
solution  of  caustic  soda,  or  of  any  medicated  solution 
desired),  through  which  the  gas  is  drawn  in  brilliant 
bubbles.  A  number  of  these  bells  or  wash-bottles  being 
kept  on  hand,  each  patient,  or  at  least  each  class  of 
patients,  may  thus  be  provided  with  an  appropriate  and 
separate  solution. 

In  regard  to  proportions,  a  mixture  very  much  used 
by  me  is  composed  of  O  two  volumes,  N^O  two  volumes, 
and  common  air  (to  be  drawn  fi-om  a  pure  source)  fonr 
volumes.  In  cases  of  extreme  vascular  torpor  and  func- 
tional inactivity  a  stronger  mixture  will  be  indicated, 
as  O  two  volumes,  N,0  one  to  two  volumes,  and  com- 
mon air  one  volume.  Such  a  mixture  is  almost  as  effi- 
cacious, in  emergencies  and  extreme  cases,  as  pure 
oxygen  ;  it  is  far  better  for  ordinary  use,  and  will  answer 
every  purpose  in  case  of  a  sudden  demand  for  the  pure 
gas.  Delicate  patients  will  require  the  weaker  mixture 
from  the  start,  and  after  a  few  days  of  the  more  active 
treatment,  very  few  cases  will  require  any  stronger.  I 
would  again  most  emphatically  repeat  what  I  have 
already  several  times  asserted,  that  a  majority  of  experi- 
menters with  oxygen  and  congeners  have  failed  and  will 
continue  to  fail  of  good  results  on  account  of  using  the 
agents  in  too  concentrated  form. 

For  a  limited  practice,  in  which  one  quality  of  gas 
must  be  made  to  serve  a  variety  of  patients,  a  com- 
promise mixture  of  equal  volumes  of  O,  N,0,  and  common 
air  is  as  strong  as  should  be  used.  This  will  be  suffi- 
ciently potent  for  the  severer  cases,  and  must  be  cau- 


314 


THE  MEDICAL  RECORD. 


[September  20,  1884. 


tiously  administered  to  susceptible  patients  and  those 
in  anything  like  a  critical  condition. 

Time  and  frequency  of  administration. — Except  in 
emergencies,  the  treatment  should  not  be  given  either 
on  an  empty  stomach  or  after  a  prolonged  fast.  In  a 
majority  of  cases  the  mid-meal  hours  between  break- 
fast and  dinner  are  most  favorable.  It  is  well  to  avoid 
giving  any  active  treatment  within  an  hour  of  any  prin- 
cipal meal,  or  at  any  time  when  there  is  present  an 
unusual  degree  of  fatigue.  Mere  weakness  or  nervous 
prostration  do  not,  however,  contraindicate,  but  are 
usually  relieved  by  oxygen. 

In  cases  complicated  with  persistent  or  periodic  neu- 
ralgia, it  will  be  advisable  to  supplement  the  regular 
daily  sitting  with  a  few  inhalations  just  before  retiring ; 
and  in  these,  as  well  as  in  extremely  "  nervous  "  or  in 
hysterical  cases,  this  evening  exhibition  should  consist 
of  as  much  as  fifty  per  cent.  N,0. 

As  a  rule,  in  ordinary  chronic  cases  one  treatment 
per  diem  is  all  that  is  advisable  ;  in  many  cases  it  is  all 
that  is  allowable.  This  should  be  carefully  borne  in 
mind  by  the  inexperienced,  since  it  is  quite  easy,  and  I 
had  almost  said  natural,  to  overdo  in  the  matter  of 
dosage,  in  the  anxiety  of  both  physician  and  patient  to 
see  palpable  signs  of  immediate  improvement. 

Methods,  dosage,  and  intervals. — When  feasible,  let 
the  patient  stand  erect,  throwing  the  shoulders  well  back 
and  as  thoroughly  as  possible  expelling  the  residual  air 
from  the  lungs  before  inspiring  the  gas;  then  with  a 
steady  effort  slowly  inspire  from  the  mouth-piece  until 
the  lungs  are  as  full  as  they  can  be  readily  filled.  Let 
the  inspired  gas  be  retained  as  long  as  convenient  with- 
out discomfort,  then  slowly  and  deliberately  expired. 
There  should  be  an  interval  of  from  five  to  twenty 
minutes,  according  to  the  nature  of  the  case,  before  a 
second  inspiration  is  given,  and  during  this  interval  the 
patient  may  walk  about,  sit,  or  recline,  as  he  seems  most 
inclined. 

In  ordinary  non-critical  cases,  accompanied  with  ven- 
ous stasis  and  general  functional  torpidity,  from  four  to 
six  inspirations,  comprehending  two  to  four  gallons,  may 
be  given  at  each  daily  stance  ;  but  this  limit  should  sel- 
dom be  exceeded.  Many  cases  will  present  in  which  two 
full  inspirations  will  be  all  that  should  be  exhibited  during 
the  twenty-four  hours.  In  this  regard  the  practitioner 
must  be  constantly  on  the  alert,  and  must  use  the  most 
careful  discretion. 

A  systematic  record  should  be  kept  of  each  case 
treated,  beginning  with  a  summarized  history,  a  thorough 
physical  examination,  an  examination  of  the  urine,  noting 
pulse-  and  respiration-rates,  capacity  of  lungs,  etc.  The 
quantity  per  diem  and  specific  gravity  of  the  urine,  as 
observed  at  stated  intervals  daily  in  critical  or  important 
cases,  and  at  least  weekly  in  all,  during  treatment,  will 
furnish  suggestive  data  from  which  to  regulate  the  qual- 
ity and  quantity  of  gas  to  be  exhibited. 

If  there  be  a  tendency  to  haemoptysis,  oxygen  is  not 
necessarily  contra-indicated,  but  evidently  should  be  ad- 
ministered with  more  caution.  I  have  not  hesitated  to 
advise  the  treatment  in  these  cases,  if  not  otherwise 
contra-indicated,  and  have  never  witnessed  any  untoward 
results ;  but  the  lungs  should  never  be  forcibly  inflated, 
nor  should  the  inspired  gas  be  so  long  retained.  As  a 
further  precaution,  which,  however,  I  am  incUned  to  think 
is  superfluous,  it  should  be  nmcb  diluted  at  the  outset 
and  gradually  increased  in  strength  with  the  progress  of 
the  case.  I  have  even  thought  the  use  of  the  gas,  with 
due  precautions,  has  eventually  lessened  the  liability  to 
hemorrhage. 

In  acute  cases,  as  of  asphyxia  from  any  cause,  alarm- 
ing dyspnoea,  cyanosis,  suspended  animation,  narcosis, 
severe  paroxysms  of  asthma,  etc,  no  definite  rules  can 
be  formulated.  The  indications  must  be  gathered  in 
each  instance  from  the  nature  and  progress  of  the  case, 
and  the  judgment  of  the  practitioner  must  in  all  cases 
supersede  all  rules. 


In  cyanosis  and  asphyxia  there  is  little  danger  of  push- 
ing the  treatment  too  rapidly  or  too  far,  short  of  posi- 
tively relieving  the  patient.  The  immediate  demand  is 
for  oxygen,  and  it  may  be  given,  freely  and  constantly, 
until  the  imminent  crisis  has  been  passed  and  the  urgent 
symptoms  are  relieved. 

A  practical  suggestion. — In  its  incipiency  every  "new" 
treatment  is  called  on  to  perform  miracles,  since  at  first 
only  the  most  inveterate  and  apparently  incurable  cases 
will  seek  its  aid.  I  would  therefore  utter  this  warning, 
and  suggest  that  no  such  cases  be  received  except  with 
the  express  stipulation  that  the  treatment  shall  be  punctil- 
iously followed  for  a  definite  period  of,  say,  not  less  than 
two,  three,  or  four  months.  It  will  be  worse  than  throw- 
ing away  time  or  than  i)lacing  pearls  before  swine  to  per- 
mit the  grand  army  of  physical  vacillators  to  spasmodically 
attempt  the  treatment,  foolishly  expecting  that  it  will  ac- 
complish greater  wonders  than  the  touch  of  Midas'  wand, 
and  fully  believing  for  a  day  that  it  is  the  latest  "  wonderful 
discovery"  among  patent  nostrums.  These  will  follow  it 
for  a  few  days  or  weeks,  and  will  insist  upon  giving  it  up 
long  before  it  has  accomplished  any  definite  or  perma- 
nent good.  They  will  be  only  a  block  of  stumbling  to 
its  success  with  others,  and  will  give  you  no  end  of  annoy- 
ance by  their  irrational  and  short-sighted  criticisms. 
Better  decline  to  treat  not  only  hopeless  incurables,  but 
all  who  will  not  stipulate  to  give  the  treatment  a  fair  and 
thorough  opportunity  to  accomplish  tangible  and  perma- 
nent results.  I  would  insist  on  this,  even  though  it 
might  appear  to  savor  of  the  methods  of  the  advertising 
charlatan.  Thus,  it  would  be  a  stroke  of  business  pru- 
dence to  charge  each  patient  a  maximum  fee  by  the 
month  for  the  first  month,  and  minimum  or  perhaps  grad- 
uated fees  for  subsequent  months  of  treatment,  since  this 
will  encourage  perseverance  on  his  part,  and  since  the 
first  month  covers  the  period  requiring  most  watchful 
care  and  intelligent  adjustment  of  all  the  conditions. 

Adjuvants, — As  regards  concurrent  treatment  by  means 
of  drugs,  this  must  be  left  to  the  discretion  of  each  practi- 
tioner, guided  by  the  exigencies  of  each  particular  case. 
It  must  not  be  omitted  whenever  it  rationally  appears  to 
be  either  synergistic  or  complementary.  To  reject  any 
source  of  aid  in  treating  maladies  is  to  raise  (or  lower) 
any  method  of  treatment  to  the  questionable  rank  of  a 
hobby. 

Theoretically  iron  is  an  oxygen  carrier,  and  in  some 
instances  it  may  be  given  with  advantage  during  an 
oxygen  course;  but  if  the  patient's  diet  be  sufficiently 
varied  so  that  it  shall  contain  the  earthy  salts  in  due  pro- 
portion, there  will  be  little  need  for  increasing  the  chalyb- 
eate element. 

To  this  end,  even  though  it  may  seem  pedantic,  I 
would  distinctly  urge,  in  connection  with  an  oxygen 
course,  the  daily  use  of  those  cereal  and  other  preparap 
tions  known  to  be  rich  in  phosphates  and  other  needed 
elements,  as  oatmeal  (coarse),  white  wheat  (crushed  or 
cracked),  whole  wheat  flour,  some  of  the  principal  ele- 
ments of  which  are  wanting  in  a  majority  of  modem 
dietaries. 

In  connection  with  the  use  of  oxygen  the  question  of 
alimentation  is  of  far  more  than  usual  significance.  In 
all  cases  the  diet  should  be  thoroughly  sustaining,  and  in 
some  it  should  be  abundant,  even  to  the  extent  of  forced 
feeding.  Bearing  this  well  in  mind,  no  specific  rules 
need  be  suggested.  The  necessity  for  an  intelligently 
selected  variety  in  diet  suggests  itself  when  we  reflect 
that  the  subtle  and  powerful  agent  to  which  we  are  sub- 
jecting our  patients  rapidly  permeates  every  molecule  of 
matter  in  even  the  remotest  tissues  of  the  body.  It  ac^ 
celerates  at  once  the  process  of  liberating  worn  material 
with  retained  and  septic  excretions,  as  well  as  that  of 
rebuilding  or  repairing  weakened  structures.  For  all 
this  work — destruction  and  reconstruction — ^liberal  sup- 
plies of  fresh  material  are  in  constant  demand,  and  must 
be  supplied  with  the  food. 

In  ail  cases  complicated  by  chronic  gastric  catarrh  or 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


315 


torpid  states  of  any  of  the  viscera,  the  somewhat  over- 
done fashion  of  hot-water  drinking,  to  the  extent  of  two 
or  three  pints  per  day  an  hour  before  meals,  will  be 
found  a  valuable  adjunct.  If  simple  hot  water  be  voted 
flat,  hot  lemonade  or  hot  soda-water  may  be  substituted, 
as  indicated.  The  washing  away  of  morbid  products  set 
free  by  the  treatment  is  also  quite  an  essential  factor ; 
hence,  in  addition  to  the  hot- water  drinking,  the  warm 
full  bath,  or  a  course  of  systematic  bathing  with  massage, 
with  also  frequent  local  lavements,  hot  douches,  etc., 
should  not  be  omitted.  These  are  invaluable  adjuvants 
to  any  treatment 

The  regulation  of  the  general  sanitary  and  hygienic 
surroundings  of  each  patient  need  not  be  adverted  to. 
The  judgment  of  all  intelligent  practitioners  will  suggest 
this.  One  exception  may  be  remarked  in  connection 
with  this  treatment :  Deprivation  in  the  matter  of  out- 
door air  and  physical  exercise,  whether  from  negligence, 
necessity,  or  indifference,  will  not  be  so  serious  a  draw- 
back as  in  case  of  ordinary  treatment,  since  superoxygen- 
ation  to  some  extent  supplies  the  lack.  But  blind  faith 
in  the  treatment  should  not  be  allowed  to  exclude  such 
aids  as  may  be  derived  from  any  and  all  adjuvants. 

I  append  reports  of  a  few  additional  cases  treated, 
hoping  that  other  experimenters  in  this  promising  field 
may  be  prompted  to  give  to  the  general  profession  the 
results  of  their  efforts,  and  that  in  due  time  we  shall  not 
be,  as  now,  literally  without  a  literature  on  the  subject. 

Case    VI. — Miss    E.    A.   W ,   aged    thirty-one; 

superintendent  of  a  fur  manufactory,  the  confinement 
and  dust  of  which  is  very  irritating.  Strumous  habit,  but 
family  history  negative.  Is  anaemic,  despondent,  and 
complains  of  a  constant  cough  ;  areas  of  dulness  over 
right  lung,  with  persistent  bronchial  irritation  and  bron- 
diial  catarrh. 

April  20th. — Placed  this  patient  on  a  mixture  of  equal 
volumes  of  O,  N,0,  and  common  air.  Lung  capacity 
bat  130  cubic  inches,  although  a  woman  of  more  than 
average  stature  and  weight  Advised  daily  exercise  in 
the  open  air  and  nutritious  diet. 

April  30th. — No  apparent  improvement ;  cough  rather 
worse ;  expectoration  very  profuse,  and  sputa  containing 
fetid  cheesy  (tubercular  ?)  matter.    Treatment  continued. 

May  loth. — Appetite  rather  better,  and  sleeps  more 
regularly;  otherwise  no  visible  improvement.  Cannot 
secure  out-door  exercise  to  any  extent.  Treatment 
changed  to  O  two  volumes,  N,0  and  atmospheric  air, 
la  one  volume.     Lung  capacity  150  cubic  inches. 

May  2oth. — Lung  begins  to  clear  up,  but  no  outward 
signs  of  improvement.  Patient  much  discouraged,  and 
only  consents  to  continue  the  treatment  on  my  positive 
assurance  that  she  has  made  some  progress.  Lung 
capacity  160  cubic  inches. 

May  30th. — Now  reports  her  general  health  as  very 
decidedly  improved ;  cough  perceptibly  better ;  her 
former  sallow  ("bilious")  complexion  has  cleared  up, 
and  is  now  fairly  ruddy.  Eats  and  sleeps  well,  and  en- 
joys a  buoyancy  of  spirits  unknown  for  years. 

June  loth. — Reports  herself  "cured,'*  and  is  loud  in 
her  praise  of  the  treatment.  Says  she  had  no  faith  in 
it  in  the  start.  Her  cough  is  almost  entirely  gone  ; 
respiratory  murmur  audible  all  over  both  lungs,  and  /las 
gained  twenty  pounds  in  flesh.  Lung  capacity  195  cubic 
inches.  Treatment  discontinued,  patient  going  to  the 
country  for  a  vacation. 

August  8th. — She  returns  for  additional  treatment. 
Took  a  severe  "cold'*  en  route  from  the  country,  and 
her  bronchial  trouble  returned.  Severe  passive  conges- 
tion of  both  lungs,  annoying  cough  with  muco-purulent 
expectoration.  Pulse,  94.  At  the  first  sitting  she  in- 
hales two  full  inspirations  of  O  one  volume,  N^O  one 
vohinle,  and  common  air  two  volumes.  Within  five 
minutes  her  pulse  falls  to  84,  and  the  immediate  dyspnoea 
is  decidedly  relieved. 

August  20th. — Some  cough  yet,  but  great  general 
improvement  is  evident     Severe  bronchial  irritadon  per- 


sists, and,  continuing  the  oxygen  treatment,  a  local  spray 
is  added.  9.  Potas.  chlor.  3j.  ad  aqua  ^iv.;  alternat- 
ing every  other  day  with  IJ.  Fl.  ext.  hyosc.  3  ss.  ad 
aqua  §  viij.  per  steam  atomizer.  Complains  of  pectoral 
and  intercostal  myalgia,  for  which  ordered  a  stimulating 
lotion  and  tonic  regimen. 

August  29th.  —  Notable  improvement  is  evident 
Bronchial  difficulty  is  much  relieved ;  myalgia  gone,  and 
not  much  cough  left     Treatment  interrupted. 

September  20th. — Treatment  resumed  every  other 
day,  improvement  having  continued  since  last  record. 

October  loth. — This  patient  now  considers  herself 
well,  but  is  advised  to  leave  the  factory  and  live  more 
out  of  doors,  if  possible. 

Saw  this  patient  six  months  later,  and  although  she 
has  not  left  the  unwholesome  factory  she  continues  well 

Case  VII. — L.  P.  N ,  aged  twenty-five;  theo- 
logical student;  nervous  temperament;  family  history 
good,  but  is  a  confirmed  dyspeptic,  and  has  spermator- 
rhoea of  several  years'  standing,  nocturnal  emissions  occur- 
ring almost  every  night  Over  the  latter  he  is  despondent, 
even  to  desperation.  Fears  he  is  going  into  a  "  de- 
cline." Studies  hard  far  into  the  night,  preaches,  be- 
comes very  excitable ;  after  which  he  suflfers  from  pro- 
tracted insomnia.  Has  consulted  a  number  of  physicians 
here  and  elsewhere,  but  without  benefit.  Is  now  trying 
movement-cure,  but  thinks  it  weakens  rather  than 
strengthens  him. 

April  13th. — Begins  the  use  of  a  mixture  composed  of 

0  one  volume,  N,0  two  volumes,  and  common  air  two 
volumes.  Lung  capacity  160  cubic  inches ;  countenance 
expressing  haggardness  and  hopelessness ;  urine  loaded 
with  oxalates. 

April  20th. — Already  reports  a  marked  change  in  his 
appetite  and  digestion.  Says  his  food  no  longer  dis- 
tresses him. 

April  30th. — Nocturnal  emissions  have  entirely  ceased ! 
He  sleeps  and  eats  well,  and  does  not  give  way  to  ex- 
citement as  formerly.  Lung  capacity  increased  to  190 
cubic  inches.     Feels  greatly  encouraged. 

May  loth. — Improvement  has  been  constant  and 
rapid  since  last  report.  Appetite  and  digestion  excel- 
lent. Has  gained  in  flesh,  feels  fresh  and  buoyant,  and 
no  return  of  emissions.  In  short,  this  patient  is  quite 
himself,  and  attributes  the  change  wholly  to  the  oxygen 
treatment.  Lung  capacity  200  cubic  inches.  No  fur- 
ther treatment  deemed  necessary,  and  patient  passed 
from  observation. 

Case  VIII. — E.  W ,   aged  forty- nine;   insurance 

agent— one  of  the  toughest  of  his  kind !  Could  talk  a 
graven  image  into  taking  a  policy,  if  he  had  time.  Mixes 
his  family  history  so  much  with  Parr's  tables  and  the 
"  actuaries'  experience  "  that  I  cannot  make  much  of  it. 
Is  suffering  from  a  chronic  "  cold  on  his  lungs,"  which 

1  diagnose  as  bronchitis — sub-acute,  with  some  pulmo- 
nary congestion.  Has  a  very  harassing  cough,  is  quite 
dyspeptic,  constipated  bowels,  harsh,  dry  skin,  haggard 
appearance. 

April  8th. — Placed  him  on  the  use,  daily,  of  the  stand- 
ard admixture  of  equal  volumes  of  O,  N,0,  and  com- 
mon air.  Lung  capacity  150  cubic  inches.  Urine  heavy 
with  chlorides,  etc. 

April  1 6th. — Decidedly  relieved;  coughs  less,  raises 
more  easily,  sleeps  and  eats  better.  Treatment  contin- 
ued, increasing  the  proportion  of  O.  Lung  capacity  180 
cubic  inches. 

April  25th. — Patient  says  he  is  pretty  much  "cured," 
and  that  the  treatment  has  benefited  his  general  health 
more  than  all  the  tonics,  bitters,  and  "blood  renewers" 
he  has  ever  taken.  Has  a  more  natural  appetite  than 
for  twenty  years,  and  is  quite  relieved  of  his  habitual 
constipation. 

May  8th. — Reports  himself  "  well ; "  no  cough,  respi- 
ration  free  and  natural,  all  his  bodily  functions  well  per- 
formed. 

Saw  this  patient  six  months  later ;  no  relapse. 


;i6 


THE  MEDICAL  RECORD. 


[September  20,  1884, 


Case  IX. — Mrs.  L.  F.  L ,  aged  forty-seven,  mar- 
ried ;  one  child,  aged  twenty.  Family  history  shows 
rheumatism  in  her  mother  (arthritis,  both  subacute,  and 
deformans),  who  is  still  living.  Father  dead.  Brothers 
and  sisters  enjoy  very  fair  health.  Some  twelve  years 
ago  had  a  miscarriage  at  three  months,  from  which  she 
made  a  poor  recovery.  Her  account  would  indicate  that 
the  secundines  were  retained  for  several  weeks,  and 
finally  expelled,  with  a  spasmodic  effort,  and  in  a  very 
fetid  condition  ;  pelvic  cellulitis  supervening  and  event- 
uating in  chronic  abscess  (intra-pelvic),  which  four 
years  ago  found  exit  through  a  tortuous  sinus  and 
reached  the  surface  in  the  right  labia  majora.  Free  in- 
cision was  made,  and  the  immediate  or  superficial  ab- 
scess cavity  was  syringed  repeatedly  with  tincture  of  io- 
dine, carbolic  acid,  and  glycerine.  It  healed  but  soon 
filled  again,  and  a  careful  exploration  with  flexible  probe 
proved  its  origin  to  be  as  above  stated,  the  seat  of  the 
original  abscess  being,  apparently,  in  the  vicinity  of  the 
right  ovary. 

During  the  past  three  years  patient  has  suffered  from 
lumbo-sacral  neuralgia  and  wandering  arthritic  pains. 
Six  months  since  her  neuralgia  culminated  in  a  painful 
and  disabling  sciatica  of  the  left  side.  After  exhausting 
all  the  domestic  remedies  to  be  had  or  heard  of,  try- 
ing salicylates,  manaca,  lotions,  and  anodynes  without 
limit,  she  came  to  me  in  sheer  desperation.  I  found  her 
anaemic,  suffering  paroxysms  of  excruciating  pain,  which 
extended  from  the  hip  to  the  ankle  ;  bowels  constipated 
and  moved  only  by  enemas,  dysuria  a  frequent  symptom, 
appetite  wanting,  and  much  gastric  distress  accompany- 
ing the  process  of  digestion.  Tonics,  iron,  stimulants, 
counter-irritation,  the  deep  injection  of  chloroform,  and 
in  some  of  the  worst  paroxysms,  of  morphia  and  atropia, 
as  also  the  constant  current,  were  all  thoroughly  tried, 
and  afforded  some  temporary  relief.  However,  these 
remedies  severely  aggravated  her  stomach  troubles,  in- 
ducing intense  cephalalgia  and  almost  unendurable  nau- 
sea ;  and  on  omitting  them  the  paroxysms  returned  with 
even  greater  severity. 

As  a  last  resort  I  advised  a  persistent  trial  of  the 
oxygen  treatment ;  and  for  the  purpose  of  making  the 
test  a  thorough  one,  took  the  patient  into  my  own 
family.  Her  complexion  is  quite  sallow,  and  skin, 
especially  on  her  hands,  covered  with  patches  of  **  salt 
rheum,"  which  has  persisted  for  thirty  years.  She  suf- 
fers from  periodic  attacks  of  rheumatic  headache,  and 
her  countenance  is  a  petrified  epitome  of  seriousness  and 
distress. 

February  ist. — Prepared  a  mixture  of  O  two  volume.^ 
N,0  two  volumes,  and  diluted  this  with  twenty  per  cent, 
of^common  air.  Of  this,  two  full  inspirations  to  be  taken 
at  10  A.M.  and  the  same  on  retiring.  Lung  capacity  100 
cubic  inches.  The  first  few  doses  of  the  mixture  pro- 
duced such  complete  muscular  relaxation  and  semi- 
insensibility  that  she  sank  helplessly  to  the  floor  unless 
supported  ;  no  unpleasant  sensations  or  effects  superven- 
ing. 

February  loth. — Sciatica  still  recurs,  but  less  fre- 
quently and  with  less  severity. 

February  20th. — Appetite  improves ;  complexion  a 
little  clearer ;  no  dysuria  except  after  the  use  of  ano- 
dynes ;  discharge  from  the  abscess  less  profuse  and  less 
fetid. 

February  28th. — No  further  discharge  from  the  ab- 
scess ;  digestion  constantly  improving  ;  sciatica  decidedly 
modified.     Lung  capacity  140  cubic  inches. 

March  5th. — Headaches  less  frequent  and  less  severe  ; 
lameness  almost  wholly  overcome  ;  complexion  rapidly 
improving.  Patient  eats,  sleeps,  and  walks  better,  and 
shows  a  buoyancy  of  spirits  unknown  for  years.  Lung 
capacity  150  cubic  inches.  The  treatment  is  continued 
with  some  interruptions,  changing  the  proportions  by 
adding  twenty  per  cent,  of  common  air  and  increasing 
to  four  full  inspirations  at  each  sitting,  twice  per 
diem. 


March  12th. — Improvement  steadily  continues  in  all 
directions. 

March  20th. — Is  gaining  flesh  quite  perceptibly,  but  it 
is  as  much  a  gain  of  quality  as  quantity.  Paroxysms  of 
headache  rare  and  light ;  sciatica  persists,  but  is  mild. 
'*  Salt  rheum  "  gone  ;  skin  smooth  as  a  child's, 

April  ist — She  declares  she  is  ready  to  **  certify"  to 
any  kind  of  statement  I  may  ask  as  to  the  efficacy  of 
the  oxygen  treatment.  Avers  that  it  has  made  her  "a 
new  woman,"  etc.  Wants  to  go  home.  I  express  my 
conviction  that  the  treatment  should  be  continued  much 
longer  to  ensure  permanent  results.  She  goes  home, 
promising  to  return  soon,  especially  if  any  old  symptoms 
reappear. 

April  24th. — Has  worked  considerably  about  the  house 
and  garden  since  last  report.  General  health  continues 
good,  but  sciatica  returns  in  mild  form.  Again  place 
her  on  four  inspirations  daily  of  equal  volumes  of  0, 
N,0,  and  common  air.     Lung  capacity  200  cubic  inches. 

May  3d. — Steady  improvement  since  last  report.  Sings 
with  good  voice,  which  she  has  not  done  for  years; 
walks  and  rides  without  pain  or  extra  fatigue  ;  also  does 
considerable  light  work  about  the  house.  Her  complex- 
ion is  now  clear  and  fairly  ruddy  ;  headaches  slight  and 
infrequent.     No  sciatica,  no  eczema. 

May  1 8th. — ^Treatment  suspended.  This  patient  has 
astonished  her  friends — and  her  physician  I 

September  15th. — Continues  to  this  date  free  from 
all  her  former  complications,  with  the  exception  of  oc- 
casional disturbances  of  a  physiologically  weak  heart. 
These  are,  however,  chiefly  or  wholly  attributable  to  her 
own  indiscretion  in  the  matter  of  over-exertion.  She 
has  attended  to  active  household  duties  ever  since  treat- 
ment was  suspended. 


THE  USE  OF  THE  GREEN  LEAVES  OF  THE 
DATURA  STRAMONIUM  IN  THE  CURE  OF 
PAINFUL  JOINT  AFFECTIONS. 

By  HAL  C.  WYMAN,  M.D., 

PROPSSSOR  OP  PHYSIOLOGY  AND  HISTOLOGY,   MICHIGAN  COLLBGK  OF  MSDiaNt, 
DBTKOIT,  MICH. 

It  may  seem  unwise  to  speak  of  the  use  of  a  remedy  that 
can  be  had  only  at  one  season  of  the  year,  yet  such  a 
remedy  I  have  found  so  invaluable  and  wide  in  its  range 
of  usefulness  that  I  am  constrained  to  risk  criticism  by 
reporting  the  success  I  have  bad  in  the  treatment  of  vari- 
ous painful  joint  affections  with  the  green  leaves  of  the 
datura  stramonium.  I  have  now  under  my  care,  in  the 
wards  of  the  Michigan  College  of  Medicine  Hospital,  a 
young  woman,  aged  twenty-two,  who  is  recovering  from 
an  attack  of  acute  rheumatic  inflammation  of  the  right 
knee-joint,  that  illustrates  the  advantage  of  treatment 
with  the  fresh  stramonium  leaves.  She  was  attacked 
three  months  ago  with  rheumatism  of  wrist  and  ankle- 
joints  upon  opposite  sides.  Under  treatment  with  sali- 
cylates the  swelling  disappeared  from  these  joints  and  re- 
appeared in  the  right  knee,  where  it  remained  until  I 
began  the  use  of  the  leaves.  In  the  meantime,  blisters 
and  iodine  ointment  externally,  iodide  of  potash,  colchi- 
cum,  and  alkalies  internally  were  tried  without  avail 
Large  and  frequently  repeated  doses  of  morphine  were 
required  at  night  to  relieve  pain  and  produce  sleep.  She 
began  to  enjoy  freedom  from  pain,  and  to  sleep,  and  the 
joint  to  improve,  immediately  the  joints  and  parts  con- 
tiguous were  enveloped  in  layers  three  or  four  leaves  deep 
of  the  freshly  picked  leaves  of  the  datura  stramonium— 
thornapple  or  Jamestown  weed,  as  it  is  sometimes  called. 
This  application*  has  been  continued  for  two  weeks.  In- 
ternally she  has  taken  infusion  of  quassia  only.  She  has 
developed  good  appetite.  The  joint  has  become  ftiobile 
and  supple,  and  swelling  is  almost  entirely  gone. 

A  feeble,  nervous  boy,  aged  ten,  had  psoas  abscess 
caused  by  carious  dorsal  vertebrae.  He  slept  badly  and 
cried  and  worried  with  pain  in  the  hip  and  lumbar  region. 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


317 


Morphia  internally  interfered  with  digestion.  His  friends 
could  not  be  prevailed  upon  to  use  it  thoroughly  by  in- 
unctions. I  directed  that  a  sufficient  number  of  the 
fresh  leaves  of  the  stramonium  be  gathered  daily  from  a 
neighboring  vacant  lot  and  applied  to  the  hip  and  lumbar 
region,  and  held  in  place  by  a  bandage.  Freedom  from 
{MUD  was  an  almost  immediate  result. 

I  could  mention  numerous  cases  of  acute  inflammation 
of  the  large  joints  of  the  body  where  great  pain,  on  attempt- 
ing motion,  was  a  prominent  symptom  that  have  occurred 
in  my  practice  during  the  summer  season.  I  have  been  in 
the  habit  of  using  the  fresh  stramonium  leaves  in  these 
cases,  and  with  the  most  happy  results,  so  far  as  the  relief 
of  pain  is  concerned.  In  the  season  when  it  is  impossible 
to  obtain  the  fresh  leaves  I  have  tried,  but  without  success, 
to  obtain  the  same  results  by  inunctions  of  stramonium 
ointment. 

The  plant  from  which  the  leaf  is  obtained  is  now 
so  common  in  the  United  States  that  one  need  ex- 
perience little  difficulty  in  getting  a  sufficient  number  of 
the  leaves  fresh  every  day  for  use  in  any  case  of  inflamed 
joint,  where  it  is  desirable  to  check  pain  and  give  physi- 
ological rest.  It  is  my  custom  to  keep  the  inflamed  and 
painful  joint  enveloped  in  the  leaves  for  a  period  of 
twenty-four  hours,  when  fresh  leaves  are  to  be  applied. 
In  some  instances  I  have  used  the  bruised  leaves  in  the 
foroi  of  paste  or  cold  poultice,  but  do  not  think  any  par- 
ticular advantage  has  resulted  from  this  method  of  appli- 
cation. All  that  seems  to  be  necessary  to  relieve  the 
pain  in  an  inflamed  joint  is  to  invest  it  with  a  layer  of 
leaves  thick  enough  to  shut  out  the  air,  and  prevent  sur- 
face evaporation.  Profuse  perspiration  from  the  skin 
over  the  joint  follows,  and  pain  and  swelling  usually 
vanish. 

.An  experience  of  twelve  summers  with  this  remedy 
convinces  me  that  with  its  help  there  is  less  frequent 
occasion  to  resort  to  the  various  immobilizing  appar- 
atus in  the  management  of  joint  troubles  than  during 
the  winter,  when  it  is  impossible  to  procure  the  fresh 
leaves,  and  that  my  summer  cases  make  better  recoveries 
—more  useful  joints — because  of  the  greater  opportunity 
given  by  the  treatment  without  fixation  apparatus  for  the 
exercise  of  the  physiological  conditions  under  which 
joints  exist. 

Opium-smoking  as  a  Therapeutic  Measure. — Dr. 
Thudichum  regards  opium-smoking  as  a  valuable  remedy 
in  colds,  hay  fever,  chronic  neuralgia,  and  hypera&sthesia, 
when  these  affections  are  rebellious  to  the  action  of 
quraine  in  large  doses  (Schmidfs  Jahrbucher^  No.  4, 
1884).  It  is  also  useful  in  attacks  of  coughing  in  phthisi- 
cal patients.  The  author  thinks  there  is  no  danger  of 
the  patient  becoming  habituated  to  the  practice,  and 
says  that  those  only  who  suffer  from  incurable  affections 
are  unable  to  cure  themselves  of  the  habit.  The  aqueous 
extract  is  used  and  the  smoke  is  to  be  deeply  inhaled. 
Dr.  Thndichum  regards  the  stories  which  have  been  told 
of  the  victims  of  opium-smoking  as  highly  colored  fables, 
bat  this  is  probably  because  he  lacks  experience,  other- 
wise he  would  not  so  unhesitatingly  recommend  such  a 
dangerous  remedy. 

Experimental  Research  Relating  to  the  Etiology 
OF  Tuberculosis.-— Geo.  M.  Sternberg,  M.D.,  F.R.M.S., 
Major  and  Surgeon,  U.S.A.,  in  a  paper  read  before  the 
Section  of  Biology  of  the  American  Association  for  the 
Advancement  of  Science,  stated  that  he  had  repeated 
Koch's  inoculation  experiments,  and  was  able  to  confirm 
liiiu  as  to  the  infectious  nature  of  tuberculo3is.  Also  as  to 
the  presence  of  the  bacillus  discovered  by  him,  in  tubercle 
nodules  in  the  lungs  and  in  tuberculous  glands  of  inocu- 
lated rabbits  and  guinea-pigs  (inoculated  with  sputum, 
containing  the  bacUlus,  from  a  phthisical  patient).    The 


experiments  of  Formad  of  Philadelphia,  by  which  he 
claims  to  induce  tuberculosis  in  rabbits  by  the  introduc- 
tion into  the  cavity  of  the  abdomen  of  finely  powdered 
inorganic  material,  have  also  been  repeated  with  an 
entirely  negative  result,  so  far  as  the  production  of 
tuberculosis  is  concerned.  The  conclusion  is  therefore 
reached  that  the  bacillus  of  Koch  is  an  essential  factor 
in  the  etiology  of  the  infectious  disease,  tuberculosis. 

Intermittent  Fever  Excited  by  Intestinal 
Worms. — Dr.  Rousseau  relates  in  L  Union  MddicaU^ 
No.  30,  1884,  the  case  of  a  young  woman,  nineteen 
years  old,  who  was  attacked  with  an  intermittent  fever  of 
very  severe  type.  The  attacks  recurred  at  frequent  in* 
tervals  for  over  a  year,  during  which  time  the  patient 
became  emaciated  and  suffered  severely  in  her  general 
condition.  Quinine  and  other  antipyretics  were  tried 
repeatedly  without  effect.  Finally  several  ascarides 
were  passed,  and  an  anthelmintic  treatment  being  then 
ordered  two  hundred  and  twenty-nine  worms  were  passed 
in  four  months.  The  intermittent  attacks  at  once  ceased 
and  did  not  recur. 

Paraldehyde  as  a  Hypnotic. — Dr.  C.  Rank  for- 
mulates the  following  conclusions  based  upon  a  number 
of  experiments  with  this  remedy  :  i.  On  account  of  its 
unpleasant  odor  and  burning  taste,  paraldehyde  is  un- 
suited  for  general  use,  especially  in  private  practice  ;  2^ 
in  physical  diseases  it  exerts  no  hypnotic  effect,  at  noost 
its  action  is  only  sedative ;  3,  parsddehyde  is  efficacious 
in  nervous  insomnia,  in  mental  excitation,  and  especially 
in  delirium  tremens;  4,  this  drug  cannot  replace 
chloral  or  morphine,  at  least  in  the  treatment  of  physical 
disorders. — Deutsche  Medicinal-Zeitung^  Avif^st  11, 1884* 

Exanthem  following  the  Use  of  Antipyrin. — 
Dr.  Paul  Ernst  reports,  in  the  Ceniralblatt  fur  Klinische 
Medicin  of  August  16,  1884,  two  cases  of  an  eruption 
caused  by  the  internal  administration  of  antipyrin.  The 
two  patients  were  a  boy  and  a  woman,  aged  respectively 
ten  and  sixty-seven  years,  yet  the  eruption  was  so  nearly 
alike  in  both  cases  that  there  could  be  little  doubt  that 
the  same  cause  was  at  work.  The  exanthem  consisted 
of  little  irregularly  rounded  pimples  lying  close  together, 
and  in  some  places  confluent  so  as  to  form  patches  of 
greater  or  less  extent,  between  which  the  skin  was  nor- 
mal, thus  giving  a  marbled  appearance  to  the  surface. 
After  about  five  days  the  eruption  began  to  fade  and  to 
assume  the  character  of  a.brownish  pigmentation,  and  in 
the  old  woman  there  were  some  faint  evidences  of  des- 
quamation. Traces  of  the  eruption  were  still  visible  at 
the  end  of  two  weeks.  The  exanUiem  was  thickest  over 
the  body,  and  on  the  extremities  the  extensor  surfaces 
were  more  covered  than  the  flexor.  In  the  boy  there 
was  some  oedema  of  the  face,  but  in  neither  case  was 
there  any  eruption  on  the  head  or  neck,  although  the 
palms  of  the  hands  and  soles  of  the  feet  were  not  spared. 
There  was  some  itching  in  the  case  of  the  woman,  but 
the  boy  did  not  complam  of  this.  The  eruption  ran  its 
course  and  disappeared,  although  the  administration  of 
the  antipyrin  was  not  interrupted.  The  writer  explains 
this  by  supposing  that  the  system  acquired  a  tolerance 
for  the  drug.  On  this  account  he  advises  a  continuance 
of  the  remedy  where  its  use  is  indicated,  despite  the 
eruption.  In  a  postscript  Dr.  Ernst  states  that  he  has 
observed  three  other  cases  of  an  exactly  similar  nature. 

OsMic  Acid  in  Epilepsy. — Dr.  Wilderniuth  has 
given  osmic  acid  in  a  number  of  cases  of  epilepsy  oc-* 
curring  in  his  practice  during  the  past  two  years  (0»- 
tralblatt  fur  Klinische  Medicin,  August  16,  1884).  It 
was  given,  in  combination  with  potassium,  in  pills,  con- 
taining each  T^g^  grain  of  the  salt.  The  largest  amount 
given  in  one  day  was  \  grain.  He  used  it  in  ten  invet- 
erate cases,  and  saw  no  result  in  seven,  in  two  the  at- 
tacks were  less  frequent,  and  in  one  a  prompt  improve- 
ment and  final  cure  was  obtained.  The  drug  caused  no 
unpleasant  symptoms  of  any  kind. 


3i8 


THE   MEDICAL  RECORD. 


[September  20, 1884. 


The  Medical  Record-. 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  bv 
WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 

New  York,  September  20,  1884. 

THE  WAVE  THEORY  OF  MENSTRUATION. 

So  rapid  has  been  the  progress  of  scientific  investigation 
and  destructive  criticism  that  there  is  now  no  English  or 
American  text-book  which  presents  correctly  the  state  of 
scientific  opinion  regarding  the  physiology  of  menstrua- 
tion. It  is  still  generally  stated  that  menstruation  is  a 
miniature  pregnancy,  in  which  there  is  a  disintegration 
and  throwing  off  of  the  mucous  membrane.  It  is  known 
now,  however,  that  such  statements  do  not  express  the 
truth,  but  that  the  denudation  is  only  partial,  and  that 
the  blood  escapes  mainly  by  diapedesis  and  by  rupture 
of  engorged  vessels.  This  view,  that  the  uterine  mucous 
membrane  is  characterized  by  a  monthly  '*  deciduosity," 
has  been  laid  aside. 

In  the  same  way  the  old  theory  of  Pfltiger,  that  men- 
struation and  ovulation  were  almost,  if  not  quite  insep- 
arable phenomena,  the  irritation  of  a  ripened  follicle  ex- 
citing reflexly  uterine  congestion,  has  also  been  disproved. 
The  iaxX  that  after  removal  of  the  ovaries  menstruation 
may  continue,  furnished  a  sufficient  refutation  of  this 
previously  very  satisfactory  explanation  of  the  menstrual 
process. 

If,  however,  it  be  true  that  menstruation  invariably 
ceases  after  removal  of  the  Fallopian  tubes,  some  in- 
genious person  may  yet  be  able  to  rehabilitate  in  a 
measure  the  reflex  hypothesis  of  Pfliiger. 

At  the  meeting  of  the  German  Naturalists  and  Physi- 
cians in  Freiburg,  February,  1883,  Professor  Hegar  re- 
viewed and  showed  the  insufficiency  of  the  various 
theories  of  menstruation.  Since  that  time  Arthur  Farre 
and  I^opold  {Archivf,  Gynecologies  Bd.  xxi.)  have  con- 
tributed further  evidence  as  to  the  independence  of  ovu- 
lation and  menstruation. 

In  a  recent  issue  of  Volkmann's  Klinischer  Vortrdge 
(No.  243),  Dr.  Carl  Reinl,  a  pupil  of  Hegar,  discusses 
the  theories  of  menstruation,  and  contributes  the  results 
of  some  careful  experiments  relating  to  what  may  bt 
called  the  wave  theory  of  menstruation. 

Professor  Goodman,  of  Louisville,  some  six  years  ago, 
advanced  the  theory  that  the  vital  activity  of  woman 
ebbed  and  flowed  rhythmically,  the  length  of  the  wave 
being  the  duration  of  a  menstrual  epoch.  Various  inves- 
tigators (Putnam- Jacobi,  Stephenson,  Rabuteau,  Hen- 
nig,  and  Von  Ott)  have  contributed  some  facts  which 
apparently  show  that  just  before  menstruation  the  vital 
powers  of  woman  are  at  the  highest,  and  that  with  the 


appearance  of  the  menses  there  is  a  gradual  fall,  with,  in 
some  cases,  a  secondary  rise. 

The  measures  of  this  alleged  increased  vitality  have 
been  the  state  of  the  heart  circulation,  the  temperature, 
and  the  excretion  of  urea.  It  has  generally  been  found 
that  the  temperature  has  been  higher,  the  blood-pressure 
greater,  and  the  excretion  of  urea  larger  in  amount  be- 
fore menstruation  than  during  or  directly  after  it 

ReinVs  observations  cover  the  subject  of  the  relation 
of  the  heat  production  to  the  menstrual  epoch.  Records 
were  made  of  the  temperature  in  eighteen  cases.  Eight 
of  these  were  healthy  women ;  on  three  ovariotomy  or 
oophorectomy  had  been  performed,  while  the  remainder 
had  some  form  of  uterine  or  ovarian  trouble.  In  the 
healthy  patients  he  established  the  existence  of  a  tem- 
perature curve,  which  reaches  its  highest  point  just  previ- 
ous to  menstruation ;  it  then  gradually  falls  during  men- 
struation, and  for  some  days  thereafter.  In  a  certain 
proportion  of  cases  during  the  first  half  of  the  intermen- 
strual period  it  falls  below  the  normal. 

In  the  pathological  cases  Reinl  still  found  marked 
evidences  of  the  temperature  wave.  Even  when  men- 
struation occurred  every  two  or  three  weeks  the  appear- 
ances of  menstruation  corresponded  with  the  top  of  the 
curve.  Perhaps  the  most  significant  £act,  however,  was 
that  in  the  castrated  women,  when  no  menstruatbn 
occurred,  the  form  of  a  periodically  returning  temperature 
wave  could  still  be  made  out 

The  observations  which  have  thus  apparently  estab- 
lished the  fact  of  a  menstrual  wave  are  most  interesting 
and  not  without  practical  significance.  It  will  still  be 
questioned,  however,  whether  because  the  pulse  is  harder, 
the  skin  hotter,  and  the  urea  excreted  greater,  therefore 
the  vital  powers  are  above  their  average  of  activity. 


MALARIA  AS  A  DEFENCE  IN  A  SUIT  TO  RECOVER  RENT. 

The  defence  of  poor  plumbing  to  a  suit  to  collect  rent 
is  a  common  one,  and  it  often  seems  to  be  the  opmion 
that  defects  of  this  kind  causing  sickness  are  suflicient  in 
law  to  prevent  a  recovery  on  the  part  of  the  landlord. 

So  generally  is  this  defence  brought  forward,  that  it 
shows  there  is  a  deep-seated  idea  that  this  is  an  excep- 
tion to  the  ordinary  rule  of  contracts.  There  may  be 
defects  in  the  roof,  or  the  furniture  may  not  be  up  to  the 
standard  promised  by  the  landlord,  but  such  defences 
are  not  often  urged  in  a  suit  for  rent  It  is  only  when 
malaria  shows  itself  that  the  tehant  feels  himself  justified 
in  leaving  the  house  or  in  refusing  to  pay  his  rent 

There  seems  to  be  no  reason,  however,  for  this  gen- 
eral belief  in  the  power  of  malaria  to  change  the  settled 
rules  of  law.  When  a  man  hires  a  house  and  examines 
it,  he  cannot,  in  general,  refuse  to  pay  rent  because 
malaria  then  existed  or  is  afterward  produced  because  of 
poor  plumbing.  He  takes  the  house  as  it  is,  and  while 
he  may  be  unfortunate  in  his  selection,  he  will  not  be 
allowed  to  leave,  and  certainly  there  is  no  rule  of  law 
which  will  allow  him  to  continue  in  the  house  and  yet  re- 
fuse to  pay  rent. 

In  the  case  where  there  is  a  positive  guarantee  on  the 
part  of  the  landlord  that  the  plumbing  is  in  good  order 
and  no  malaria  exists,  there  seems  to  be  a  little  confu- 
sion in  the  decisions,  but  die  general  opinion  is,  that  i( 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


319 


notwithstanding  the  guarantee,  the  tenant  examines  the 
bouse  and  is  apparently  satisfied  by  accepting  the  lease, 
he  cannot  afterward  refuse  to  pay  rent.  In  case  the 
tenant  relies  on  the  landlord's  statements  and  makes  no 
examination  of  the  condition  of  the  house,  the  decisions 
are  in  favor  of  allowing  him  to  leave  the  house,  and  no 
rent  can  be  recovered. 

An  interesting  case  was  decided  not  long  since  in  this 
dty  which  seems  to  give  the  tenant  rights  under  the 
Health  laws  to  leave  his  house  and  refuse  to  pay  rent 
The  following  is  the  statement  of  the  case  :  ''  In  a  suit 
for  rent  claimed  to  be  due  from  a  tenant  of  a  suite  of 
rooms  in  an  apartment  house,  it  appeared  that  the  de- 
fendant's wife  and  servants  were  taken  sick  by  inhaling  a 
malarial  or  poisonous  gas  in  the  apartments  occupied  by 
them;  that  this  unhealthy  condition  of  the  apartments 
was  [owing  to  the  [defective  condition  of  the  general 
plumbing  work  of  the  house,  of  which  the  landlord  was 
notified  by  orders  received  from  the  Board  of  Health, 
requiring  him  to  have  changes  made  in  the  plumbing 
work,  and  which  unhealthy  condition  could  have  been 
removed  if  he  had  complied  with  those  orders  ;  that  the 
defendant  waited  for  two  weeks,  and  finding  that  nothing 
was  done  on  the  part  of  the  landlord,  left  under  the  ap- 
prehension that  he  was  imperilling  the  health  of  himself 
and  fiunily  by  remaining.''  Under  these  circumstances, 
the  judge  who  tried  the  case  decided  that  this  was  what 
is  called  in  law  a  constructive  eviction,  and  the  tenant 
could  not  be  forced  to  pay  rent  during  that  portion  of  his 
lease  subsequent  to  the  removal. 

The  decision  has  recently  been  affirmed  by  the  Gen- 
eral Term  of  the  Court  of  Common  Pleas,  and  unless  re- 
versed by  the  Court  of  Appeals,  which  is  unlikely,  will 
be  the  law  in  the  future.  It  may  be  said  in  general  that 
the  policy  of  the  law  is  becoming  more  favorable  to 
tenants  in  some  particulars,  but  the  main  principles  of 
contract  law  will  always  apply  to  leases. 


WHEN   SHOULD   POISON   LABELS  BE   USED? 

A  CASB  has  recently  occurred  in  Philadelphia  which 
raises  a  nice  question  as  to  what  prescriptions  should  be 
labelled  '*  Poison."  The  Pennsylvania  stotute,  and  that 
of  almost  every  other  State,  is  to  the  effect  that  <'  No 
apothecary,  druggist,  or  other  person,  shall  sell,  .  .  . 
by  retail,  any  morphia,  strychnia,  .  ,  ,  except  upon 
the  prescription  of  a  physician  or  on  the  personal  ap- 
plication, .  .  .  and  in  all  cases  of  such  sales  the 
word  '  Poison '  shall  be  carefully  and  legibly  marked  or 
placed  upon  the  label,"  etc. 

In  the  case  referred  to  a  physician  ordered  pills  con- 
taining one-twentieth  of  a  grain  of  strychnia  for  a  pa- 
tient ;  a  number  of  persons  (not  previously  adjudged 
lunatics)  believing  that  such  diminutive  pills  could  con- 
tain nothing  prejudicial  to  health,  undertook  to  see  who 
could  swallow  most  of  them  in  ar  given  time..  The 
youngest  of  the  party  took  fourteen,  representing  seven- 
tenths  of  a  grain,  and  died.  The  erudite  corotier,  after 
holding  an  inquest  of  great  length,  has  instructed  his 
jury  to  find  the  dispensing  clerk  responsible  for  the 
death  of  the  girl  in  not  labelling  the  pill-box  "  Poison."   , 

Aside  from  the  fact  that  from  the  manner  in  which 
tile  case  has  been  conducted,  it  looks  very  like  a  case  of 


libel,  the  question  arises,  Are  all  prescriptions  contain- 
ing a  poison  to  be  labelled  "  Poison  "  ?  or  shall  only 
those  prescriptions  containing  the  drugs  mentioned  in  the 
statute  be  labelled  as  poison  ?  The  statute  in  the  Penn- 
sylvania  books  is  clearly  deficient,  as  it  only  includes 
morphia,  strychnia,  arsenic,  prussic  acid,  and  corrosive 
sublimate.  Certainly  it  would  be  absurd  to  require  the 
apothecary  to  label  pills  containing  one-twentieth  of  a 
grain  of  strychnia  "  Poison,"  and  at  the  same  time  allow 
him  to  sell  an  ounce  of  tartar  emetic  or  one  grain  of 
atropine  to  any  person  without  the  cautionary  label. 
Yet  this  is  clearly  what  the  law  would  allow,  and  we  do 
not  see  how  he  could  be  prosecuted  for  it.  But  it  is 
equally  absurd  to  require  him  to  put  the  fpoison-label 
on  every  prescription  containing  a  poison ;  for  in  this 
case  it  would  be  the  exception  when  a  prescription 
would  not  be  labelled  as  poisonous.  Brown-S^quard's 
neuralgic  pills,  Dalby's  carminative,  Mitchell's  tonic  pills, 
Dover's  powder,  and  fully  one-half  of  the  prescrip- 
tions sent  out  by  physicians  would  be  illustrated  with 
the  skull  and  cross-bones.  Such  is  clearly  not  the  pur- 
pose of  the  law,  and  it  would  be  not  only  absurd  but 
puerile,  especially  when  pills  are  dispensed,  as  no  one 
could  take  two  pills  by  mistake  for  one ;  and  though  the 
law  has  a  good  deal  of  presumption,  it  has  no  right  to 
presume  that  the  physician  is  prescribing  for  a  patient 
whose  friends  are  without  proper  mental  balance.  Had 
the  prescription  in  question  called  for  gr.  v.  of  strychnia, 
and  f^xiiss^  of  water,  in  teaspoonfiil  doses,  the  drug* 
gist  would  very  properly,  as  he  says,  have  labelled  it  as 
poisonous,  because  a  careless  person  might  take  a  table- 
spoonfiil  of  it,  or  else,  as  many  people  do,  might  turn 
the  bottle  up  to  the  mouth  and  guess  that  the  proper 
amount  had  been  swallowed.  As  an  example  of  the 
absurdity  to  which  this  hair-splitting  construction  of  the 
law  would  be  reduced,  the  druggist  in  question  gives  the 
following,  taken  from  his  file  :  **  Eight  suppositories,  each 
containing  half  a  grain  of  aqueous  extract  of  opium.  Use 
one  "  (here  the  opium  contains  morphia,  and  the  label 
must  be  used)  ;  and  adds,  '^  If  some  lunatics  will  banter 
each  other  as  to  how  many  of  these  they  can  insert  into 
their  respective  rectums,  they  will  also  be  subjects  for 
inquest."  But  the  manifest  absurdity  of  the  coroner's 
construction  is  still  further  seen  when  it  is  remembered 
that  scores  of  patent  medicines  are  sold  without  the 
poison-label ;  in  fact,  we  do  not  remember  ever  to  have 
seen  such  a  label  on  a  patent-medicine  bottle.  Yet  we 
have  known  a  woman  to  die  within  two  minutes  after 
taking  a  triple  dose  of  a  patent  cough-mixture,  without 
previously  shaking  the  bottle.  Nor  have  paregoric  or 
any  of  the  many  soothing  syrups  cautionary  labels.  The 
Philadelphia  coroner  may  not  be  much  of  a  mathemati- 
cian, but  he  has  evidently  not  foi^otten  the  reductio  ad 
aksurdum.  

MULLEIN  LEAVES  IN  PHTHISIS. 
At  the  late  meeting  of  the  International  Medical  Con- 
gress at  Copenhagen,  Dr.  Quinlan,  of  Dublin,  read  a  paper 
in  which  he  advocated  the  employ  of  mullein  leaves  in 
phthisis,  claiming  extraordinary  success  in  the  treatitoent 
of  this  disease  by  the  free  use  of  a  decoction  in  milk  of 
this  plant,  or  rather  wtidy  for  it  is  one  of  the  most  com* 
mon  of  our  native  weeds,  growing  by  the  roadside  and  in 


320 


THE   MEDICAL   RECORD. 


[September  20,  1884. 


neglected  fields.  Mullein  is  known  to  botanists  as  the 
verbascum  thapsus,  and  has  honorable  mention  in  the 
Codex  of  France  under  the  name  of  Moline,  bouillon 
blanc  ;  entering  into  the  composition  of  the  quaire  fleurs 
pectorales.  The  mode  of  preparation  is  to  infuse  an 
ounce  of  the  dried  leaves,  or  the  equivalent  of  the  fresh, 
in  a  pint  of  milk,  to  boil  for  ten  minutes,  and  then  to 
strain.  This  infusion  is  administered  warm  to  the  patient, 
with  or  without  a  little  sugar.  The  whole  pint  is  given 
in  two  doses  during  the  twenty-four  hours.  The  hot  de- 
coction is  said  to  be  very  easing  to  consumptive  coughs, 
so  that  during  its  use  the  ordinary  cough  mixtures  may 
be  dispensed  with.  Its  power  of  checking  phthisical 
looseness  of  the  bowels  is  said  ^  to  be  very  marked.  In 
early  cases,  according  to  Dr.  Quinlan,  the  mullein  milk 
appears  to  act  very  much  in  the  same  manner  as  cod- 
liver  oil,  than  which  it  is  much  more  palatable.  A  large 
number  of  cases  of  pulmonary  consumption  have  been 
treated  in  St.  Vincent  Hospital,  Dublin,  exclusively  on 
mullein,  and  it  is  said  that  crowds  of  patients  have  been 
attracted  to  this  hospital  by  the  wonderful  results  which 
have  been  obtained  from  this  singularly^simple  treatment. 
In  phthisical  coughs  great  relief  is  said  to  follow  smoking 
dried  mullein  leaves  in  the  same  manner  as  tobacco.  Dr. 
Quinlan  showed  at  the  meeting  of  the  Congress  cigar- 
ettes made  of  mullein  leaves,  which  are  said  to  be  very 
pleasant  to  smoke.  It  is  asserted  that  in  pretubercular 
and  early  cases  of  pulmonary  consumption  mullein  ap- 
pears to  have  a  distinct  weight-increasing  power,  and  to 
be  an  excellent  palliative  to  the  cough  in  the  later  stages, 
besides  being  the  very  best  remedy  to  antagonize  loose- 
ness of  the  bowels. 

Wood,  in  the  U.  S.  Dispensatory,  speaks  of  mullein 
leaves  as  '^  demulcent  and  emollient,''  and  as  reputed  to 
possess  "  anodyne  properties  which  render  them  useful  in 
pectoral  complaints." 


THE  NEXT  MEETING  OF  THE    INTERNATIONAL  MED- 
ICAL CONGRESS. 

It  is  a  matter  of  gratification  and  pride  that  the  Inter- 
national Medical  Congress  has  decided  to  hold  its  next 
meeting  in  this  country.  The  American  profession,  how- 
ever, cannot  too  soon  be  made  to  feel  that  it  has  ac- 
cepted no  small  responsibility,  and  that  it  must  put  forth 
especial  effort  in  order  to  acquit  itself  well.  So  far  as 
American  hospitality  and  the  ability  generously  to  offer 
it  are  concerned  we  have  little  to  fear.  But  that  the 
literary  and  scientific  contributions  come  up  to  the  high 
standard  heretofore  observed  in  these  Congresses  is  a 
matter  of  more  concern.  Unquestionably  American 
physicians  can  respond  successfully  in  this  direction  if 
the  effort  is  made,  as  there  is  little  doubt  will  be  the  case. 
We  trust  that  our  readers  will  begin  at  once  to  consider 
whether  they  wish  to  take  part  in  the  Congress,  and  if  so, 
to  see  that  they  bring  to  it  something  worthy  of  the  occa- 
sion. Three  years  is  none  too  long  to  expend  in  such 
preparation. 

Naturally,  the  character  of  the  papers  read  at  the 
Congress  in  question  will  depend  greatly  upon  the  judi- 
cious work  of  the  organizing  committee.  There  should 
be  no  effort  spared  to  get  our  most  representative  men 
and  no  ill-timed  charity  in  selecting  the  wheat  from  the 
great  amount  of  chaff  that  will  surely  be  offered.     No 


papers  shoild  be  accepted  that  do  not  bear  the  stamp  of 
originality  and  merit. 

Some  practical  difficulties  will,  we  fear,  be  met  with  by 
reason  of  the  climate  of  Washington,  where  the  Congress 
is  to  be  held.  In  July  and  August  the  heat  is  liable  to 
be  intense,  and  to  unfit  even  the  most  enthusiastic  for 
scientific  work  or  social  enjoyment  It  would  be  im- 
possible probably  to  get  many  European  physicians  from 
their  work  so  early  as  May  or  June.  In  September  there 
might  perhaps  be  cooler  weather. 

Still  we  do  not  think  that  climatic  objections  will  be 
insuperable,  especially  since  the  hotel  accommodations  in 
Washington  are  so  ample,  and  the  Potomac  has  almost 
always  a  cool  breeze.  Three  years  from  now,  however, 
we  shall  advise  our  prospective  European  visitors  to 
bring  the  lightest  clothes  and  to  be  prepared  for  the 
most  liberal  diaphoretic  activity. 


THE  GROSS  MEMORIAL  AGAIN. 
The  sting  of  death  is  sometimes  in  the  imbecility  of 
posthumous  admirers.  The  Chicago  Medical  Journal  and 
Examiner  has  made  a  siurprising  display  of  unpleasant 
feeling  as  regards  the  position  of  The  Record  toward 
the  proposed  Gross  Memorial  Professorship.  We  have 
not  seen  so  near  an  approach  to  billingsgate  in  a  medical 
journal  for  a  long  time. 

We  confess  that  we  do  not  understand  the  cause  of  the 
JournaPs  outburst.  We  honor  the  memory  of  the  late 
Dr.  Gross  ;  we  urge  that  his  memory  have  a  fit  memorial 
His  is  the  greatest  name  in  American  surgery  ;  we  pro- 
test against  its  being  buried  in  a  ''memorial  professor- 
ship "  in*  a  private  (as  distinguished  from  a  State)  medi- 
cal school.  Medical  history  furnishes  no  such  project 
as  that  which  is  now  being  set  before  us.  We  advise 
against  it  because  the  plan  is  unwise  and  will  not  arouse 
the  sympathy  of  the  profession.  We  urge  in  its  place 
that  there  be  founded  a  memorial  laboratory  or  a  lecture- 
ship similar  to  those  by  which  celebrated  physicians  of 
London  have  been  honored.  Every  doctor  in  the  coun- 
try, with  a  spark  of  generosity  in  him,  will  gladly  forward 
such  a  plan,  and  it  will  succeed.  But  to  set  up  as  a 
memorial  to  a  great  man  a  didactic  professorship  for 
the  yearly  benefit,  not  of  doctors,  but  of  students,  a  com- 
monplace, utterly  local  and  never-to-be»foiigotten  invest- 
ment is  ridiculous  1 

The  Journal  is  mistaken  in  arguing  with  so  much  point 
and  courtesy  that  The  Record  is  "untruthful,"  '*  jealous," 
"  spiteful,''  and  "  sordid."  It  is  simply  a  question  of 
properly  and  successfully  rendering  homage  to  a  dis- 
tinguished name.  We  believe  thoroughly  that  Jefferson 
Medical  College  took  up  the  matter  in  good  £sdth  and  io 
perfect  unselfishness.  We  do  say,  however,  that  it  was 
not  only  unwise  but  in  bad  taste  for  it  to  organize  a 
scheme  which  will  help  itself  as  much  as  it  honors  Gross. 
We  have  the  "  efiroAtery  "  still  to  reiterate  that  the  above 
expresses  the  views  of  most  of  the  profession. 

Uatie  Journal  still  believes  that  our  interpretation  of 
the  general  feeling  is  not  correct,  we  refer  its  editor  to 
Gaillard's  Medical  Journal^  the  Medical  Age^  the  De- 
troit Lancet,  the  Cincinnati  Lancet  and  CHniCy  the  Indi- 
ana Medical  Monthly^  the  Peoria  Medical  Monthly y  widi 
other  journals  yet  to  come. 


September  20,  1884*  J 


THE  MEDICAL  RECORD. 


321 


It  is  said  that  Lord  North's  third  wife  was  of  so  in- 
flammable a  temperament  that  for  three  days  before  the 
wedding  she  had  to  be  kept  packed  in  ice.  We  would 
in  all  courtesy  suggest  that  a  similar  course  would  be 
advisable  for  the  editor  of  our  valued  contemporary  pre- 
vious to  his  ventures  in  polemics.  Being  cooled  to  below 
the  point  of  unmannerly  vituperation,  he  may  see  that 
possibly  all  is  not  guile  in  New  York,  and  that  we  may 
be  quite  sincere  in  urging  the  views  we  have  presented. 

We  certainly  trust  that  there  will  be  no  quarrel  over 
the  matter.  It  would  require  very  little  change  to  secure 
perfect  unanimity  in  working  for  the  honor  of  the  la- 
mented Gross. 

As  bearing  upon  the  general  question,  we  append  the 
following  from  a  well-known  Jefferson  Alumnus  in  the 
western  part  of  this  State.  The  writer  puts  the  case 
with  fairness,  and  is  responsible  for  his  facts : 

Your  views  on  the  subject  of  the  proposed  memo- 
rial to  the  late  Professor  Gross  meet  with  a  hearty  re- 
sponse from  many  of  the  alumni  of  Jefferson  Medical 
College.  As  a  member  of  the  Auxiliary  Committee,  ap- 
pointed to  solicit  contributions,  I  find  that  most  of  the 
old  "  Jeff."  men  whom  I  approach  are  unwilling  to  help 
in  any  movement  which  will,  at  the  expense  of  the  alumni, 
only  give  another  prize  to  be  electioneered  for  in 
the  Board  of  Trustees  of  the  College.  All  old  Jeffer- 
son men  know  what  a  close  corporation  said  Board  is, 
and  when  they  remember  that  neither  Professor  Pan- 
coast  nor  Professor  Gross,  out  of  their  large  estates,  left 
a  cent  to  the  school  which  so  long  honored  them,  it 
would  seem  that  these  great  men  saw  nothing  in  the 
spirit  which  animates  the  Trustees  to  warrant  giving 
them  the  disposal  of  any  endowed  chairs.  The  last 
three  appointments  to  professorships  in  Jefferson  were 
made  notoriously  for  the  following  objects — first  to  con- 
ciliate Philadelphia  society,  and,  second,  to  drains  students 
from  the  West  It  is  high  time  that  the  alumni  of  a 
college,  who  in  after  life  do  so  much  for  its  benefit, 
should  have  some  voice  in  the  management.  Let  the 
Alumni  Associatibn  have  the  election  of  one-half  the 
Board  of  Trustees,  or  a  confirmatory  vote  on  profes- 
sional appointments,  or  the  nomination  to  the  Trustees 
of  names  to  fill  vacancies  in  the  teaching  body,  if  they 
are  to  be  expected  to  aid  the  College  in  the  means  for 
higher  education.  I  am  as  fond  of  my  alma  mater  as  the 
next  man,  and  look  with  pride  at  the  signatures  on  my 
diploma,  but  I  cannot  avoid  the  chagrin  which  comes 
over  me  every  year  as  I  peruse  the  annual  announce- 
ment, and  see  the  miserable  subterfuges  which  are  in- 
serted therein  to  appease  the  clamor  for  higher  stand- 
ards and  yet  avoid  any  rock  which  will  lower  the  fees  of 
the  Faculty.  Such  an  instance  is  found  in  the  last  an- 
nouncement, in  which  the  preliminary  examination  re- 
quired by  the  laws  of  certain  States  is  offered  only  to 
those  who  intend  to  locate  in  those  States,  instead  of  be- 
ing required  of  all  students.  The  auri  sacra  fames  has 
its  seats  in  the  councils  of  all  our  educational  institu- 
tions, but  the  alumni  of  Jefferson  will  not,  as  a  body, 
respond  to  that  thirst  until  a  change  comes  over  the 
spirit  of  those  who  control  its  affairs. 

A  Jefferson  Man. 


The  Fort  Plain  Fasting  Girl. — Dr.  Darwin  Pot- 
ter, of  Fort  Plain,  N.  Y.,  has  examined  the  alleged  fast- 
ing girl  of  that  place.  He  finds  the  case  to  be  one  of 
very  much  the  kind  we  had  stated.  The  claim  to  having 
Casted  for  one  hundred  and  eighty-eight  days  is  made 
preposterous  by  the  girFs  well-nourished  state.  She  has 
chorea,  and  is,  as  we  suggested,  undoubtedly  hysteri- 
cal. 


%«mi&  0f  tiut  tSftejeli. 


The  Rhinelander  Case. — The  recent  investigation 
into  the  mental  condition  of  William  C.  Rhinelander  by  a 
commission  appointed  by  the  Court  of  General  Sessions 
has  attracted  a  great  deal  of  attention  on  the  part  of  the 
community  at  large.  It  was  begun  for  the  purpose  of 
enabling  Recorder  Smyth  to  decide  whether  Rhinelander 
should  be  called  upon  to  plead  to  an  indictment  for  as- 
sault upon  John  Drake,  a  lawyer  of  this  city.  It  was 
alleged  that  Rhinelander  was  insane  and  more  fit  for  an 
asylum  than  a  trial  in  a  court  of  law.  The  investigation 
continued  for  a  number  of  weeks  during  the  summer 
before  the  commission,  consisting  of  Drs.  Detmold  and 
Nolan  and  Edward  Patterson,  a  lawyer.  The  testimony 
was  conflicting  and  Rhinelander  vigorously  contested 
the  idea  that  he  was  insane,  claiming  that  he  desired  and 
ought  to  have  a  criminal  trial.  The  commission  have 
just  reported  to  the  Recorder,  Drs.  Detmold  and  Nolan 
holding  that  he  is  insane,  and  Mr.  Patterson  that  he  is 
not.  Under  the  law  the  Recorder  can  adopt  either  report 
he  chooses,  and  he  is  now  engaged  in  examining  the 
voluminous  testimony  produced,  in  order  to  arrive  at 
some  conclusion. 

The  Death  of  Dr.  Robert  J.  HEiNMttLLER. — ^At  a 
special  meeting  of  the  members  of  the  Fourth  Division 
of  the  Health  Department  of  the  City  of  New  York, 
held  September  2,  1884,  the  following  resolutions  were 
adopted : 

Whereas^  We  have  learned  withjdeep  sorrow  and  re- 
gret of  the  death  of  our  late  colleague.  Dr.  Robert  J. 
Heinmiiller ;  therefore,  be  it 

Resolved^  That  in  the  death  of  Dr.  Heinmtlller,  this 
Department  has  lost  one  of  its  most  faithful  and  efficient 
officers,  and  we,  his  associates,  a  friend  whose  many 
noble  qualities  of  mind  and  heart  had  endeared  him  to 
each  and  all  of  us  ;  and  the  orofession  has  lost  one  of  its 
most  promising  young  members. 

That  we  tender  to  the  family  of  the  deceased  our 
deepest  sympathy  in  their  great  bereavement. 

That  a  copy  of  the  proceedings  of  this  meeting  be  sent 
to  the  family,  and  to  the  medical  journals  for  publication. 
J.  B.  Taylor,  MfD., 
J.  B.  Lenehan,  M.D., 
George  S.  Conant,  M.D., 
J.  N.  McChesvey,  M.D., 
J.  C.  Conover,  M.D., 

Committee. 

The  Cholera. — On  September  14th,  the  cholera  at 
Naples  showed  evident  signs  of  abating.  On  the  i6th, 
there  were  only  470  new  cases  and  167  deaths.  The 
total  number  of  deaths  at  Naples,  up  to  the  day  men- 
tioned, is  estimated  to  be  about  3,700.  This  would 
represent  between  eight  and  nine  thousand  cases,  since 
the  mortality  has  been,  on  the  whole,  rather  below  its  aver- 
age. In  other  parts  of  Italy  the  cholera  continues  to  keep 
its  hold,  but  makes  no  alarming  progress.  Reports  are 
sent  in  from  thirteen  different  provinces,  but  the  total 
number  of  cases  ranges  between  one  and  two  hundred, 
with  a  mortality  considerably  less  than  fifty  per  cent. 

In  France  there  continues  to  be  occasional  sporadic 


322 


THE   MEDICAL  RECORD. 


[September  20, 1884. 


outbreaks.  Some  cases  are  still  reported  from  Toulon 
and  Marseilles,  In  the  Eastern  Pyrenees  there  are  forty- 
seven  places  where  the  disease  has  appeared.  In  all 
France  it  is  estimated  that  there  have  been  5,200  deaths 
in  207  cities  and  villages. 

Cholera  is  reported  from  half  a  dozen  Spanish  towns, 
but  in  none  of  them  has  the  disease  made  great  ravages, 
if  we  may  trust  reports.  At  date  of  writing,  indeed,  there 
have  not  been  200  deaths  from  cholera  ih  all  Spain. 
On  the  whole,  the  epidemic  appears  to  have  spent  its 
force.  We  may  estimate  that  it  will  leave  with  a  record 
of  10,000  deaths  and  two  or  three  times  as  many  cases 
of  sickness. 

The  Academie  de  Medicine,  of  Paris,  has  appointed 
a  cholera  commission,  consisting  of  MM.  Brouardel, 
Marey,  Rochard,  Proust,  de  Mussey,  Fauvel,  Legouest, 
and  Besnicr. 

Protesting  against  Compulsory  Vaccination. — A 
despatch  says  that  over  3,000  people  at  Leicester,  Eng- 
land, have  been  summoned  for  defying  the  vaccination 
law,  the  feeling  against  which  is  very  bitter  all  over 
England. 

Giving  Commissions  on  Dental  Patients. — We  are 
not  aware  that  there  is  an  Odontological  Code  of  Ethics, 
written  or  unwritten.  Bat  whether  there  is  or  not,  there 
ought  to  be  some  moral  prohibition  put  upon  the  prac- 
tice by  certain  dentists  of  offering  a  percentage  on  all 
patients  sent.  The  practice  seems  to  be  to  circulate 
cards  among  physicians  announcing  that  '*  we  allow  you 
twenty-five  per  cent,  of  all  money  received  from  patients 
whom  you  send  us." 

The  English  Army  Surgeons,  about  two  thousand 
in  number,  are  to  change  their  uniform  from  scarlet  to 
blue. 

A  Testimonial  to  Dr.  H.  D.  Schmidt. — We  learn 
from  the  New  Orleans  Medical  and  Surgical  Journal 
that  the  friends  of  the  eminent  pathologist,  Dr.  H.  D. 
Schmidt,  have»organized  for  the  purpose  of  procuring  and 
presenting  a  testimonial  portrait  of  him  to  Charity  Hos- 
pital. The  presentation  was  to  have  been  made  the  first 
Monday  in  September.  Dr.  Schmidt  xs  facile  princeps 
the  pathologist  of  the  South,  and  deserves  this  act  of  ap- 
preciation from  the  profession. 

The  Will  op  the  Late  Dr.  John  G.  Adams. — Dr. 
Adams,  by  his  will,  bequeaths  $5,000  to  the  Presbyterian 
Hospital  for  a  free  bed  for  the  sick  poor  of  the  Fifth 
Avenue  Brick  Church  ;  $2,500  to  the  Bridgeport  Protes- 
tant Orphan  Asylum  and  Hospital ;  $500  each  to  the 
Physicians*  Mutual  Aid  Association  and  the  New  York 
Training  School  for  Nurses.  His  medical  library  is  be- 
queathed to  the  New  York  Academy  of  Medicine.  Dr. 
Adams  revokes  in  a  codicil  a  bequest  of  $5,000  to  the 
New  York  Academy  of  Medicine. 

Cholera  and  Tobacco. — There  seems  to  be  a  belief, 
among  the  newspaper  section  of  the  city  at  least,  that 
tobacco  has  some  prophylactic  power  against  cholera. 
The  Times  correspondent  who  visited  Toulon  and  Mar- 
seilles kept  tobacco  in  his  mouth  while  in  the  infected 
districts  and  hospitals.  Mr.  George  Augustus  Sala  has 
asserted  that  in  past  epidemics  tobacco-smokers  have 
had  some  exemption  from  the  disease.     Now  experience 


has  shown  that  acid  solutions  prevent  the  development 
of  the  cholera  germ,  and  that  this  organism  cannot  easily 
pass  through  an  acid  stomach  into  the  intestine.  But 
the  use  of  tobacco  promotes  a  flow  of  alkaline  saliva 
which  is  swallowed,  thus  preparing  a  flowery  path  for  the 
bacillus  to  enter. 

Prof.  Mallet,  M.D.,  LL.D.,  Ph.D.,  has  been  ap- 
pointed to  the  chair  of  Chemistry  in  Jefferson  College,  as 
successor  to  the  late  Professor  Rogers.  The  school,  in 
selecting  Dr.  Mallet,  has  successfully  pursued  its  policy 
of  taking  the  best  men  obtainable  for  its  professorships. 

Trouble  among  the  Homoeopaths  at  Washing- 
ton, D.  C. — ^The  homoeopaths,  or  at  least  certain  persons 
practising  under  that  trade-mark  in  Washington,  D.  C, 
are  complaining  that  the  trustees  of  the  Garfield  Me- 
morial Hospital  give  them  no  share  in  its  management 
To  offset  this,  the  managers  of  the  "  National  Homoeo- 
pathic Hospital"  (that  is  to  be)  have  issued  an  appeal  to 
the  homoeopathic  societies  throughout  the  country  to 
assist  in  a  grand  national  fair  to  be  held  in  Washington 
in  December  next. 

A  Homoeopathic  Fraud  Exposed. — ^Wbile  on  the 
subject  of  homoeopathy,  it  may  be  of  interest  to  note  the 
following  case  of  poisoning  recently,  reported  in  the  Aus- 
tralasian Medical  Gazette :  *'  A  homoeopathic  practitioner 
named  Giinst  was  called  in  to  attend  a  young  woman 
suffering  fi-om  sleeplessness  and  neuralgia,  for  which  he 
prescribed  morphia  and  quinine.  His  explanation  is  that 
by  some  bungling  in  the  use  of  Hahnemannic  symbols,  the 
powder  ordered  actually  contained  ten  grains  of  hydro- 
chlorate  of  morphia  and  five  grains  of  quinine,  and  as  the 
directions  given  to  the  patient  had  been  to  take  the  pow- 
der  at  once,  the  unfortunate  woman  was  killed.  This 
accident  of  the  poisoning,  however,  is  not  the  main  point 
of  interest  now.  In  the  evidence  given  by  Dr.  Giinst  at 
the  inquest,  he  explained  that  what  he  intended  to  order 
was  half  a  grain  of  morphia,  and  this  admission  at  once 
puts  the  treatment  out  of  the  compass  of  homoeopathy." 

The  Code  of  the  Nebraska  Doctor. — ^The  Omaha 
doctors  are  being  greatly  slandered  or  they  are  in  a  bad 
way.  A  correspondent  from  that  city  asserts  that  the 
code  of  ethics  is  "  Every  man  for  himself  and  the  devil 
take  the  hindermost."  This  code  is  recommended,  how- 
ever, by  a  Western  exchange  as  being  devoid  of  all  possible 
hypocrisy  at  least. 

The  Missouri  State  Medical  Society  is  accused, 
like  the  New  York  Society,  of  being  overrun  with  special- 
ism. There  is  fault  on  both  sides.  Papers  are  wanted, 
and  specialists  generally  are  the  most  ready  to  write. 
Let  the  general  practitioner  assert  himself,  therefore,  but 
also  let  the  organizing  committees  help  him  a  little  more 
than  is  now  the  case. 

Pasteur  in  Wax. — A  foreign  exchange  states  that 
there  has  been  placed  in  the  Musie  Grivin  a  represen- 
tation in  wax  of  Pasteur,  with  his  assistants  engaged  in 
the  act  of  inoculating  a  dog  against  rabies.  Wax  works 
have  become  the  modern  barometers  of  fame. 

The  Important  Fact  is  being  circulated  that  Mr. 
Blaine  is  homoeopathic  in  his  medical  beliefs.  However 
this  may  be,  he  seems  a  big  pill  to  some  people. 


September  20,  1884.] 


THE   MEDICAL   RECORD. 


323 


£xcisiON  OP  THE  Pylorus  for  Malignant  Disease 
was  performed  by  Dr.  Randolph  Winslow,  of  Baltimore, 
recently  at  the  University  Hospital.  The  patient  was  a 
woman,  forty-two  years  of  age,  who  had  suflFered  for  over 
a  year  and  was  much  emaciated.  She  died  of  shock  a 
few  hours  after  the  operation.  So  far  as  we  can  learn, 
this  is  the  second  operation  of  the  kind  in  this  country. 
Both  have  been  unsuccessful 

Doctors  in  Denver. — The  Denver  Medical  Times 
says,  that  about  twenty  new  doctors  have  located  in 
Denver  v^ithin  the  past  three  months.  The  ratio  of 
doctor  to  inhabitant  now  is  one  to  two  hundred  and  fifty. 
Denver  has  also  one  medical  college,  twenty-five  to  thirty 
professors,  and  five  or  six  hospitals. 


%i^w:\s  xrf  ^ocijctiieB, 


MEDICAL  SOCIETY  OF  VIRGINIA. 

Fifteenth  Annual  Session,  held  at  Rawley  Springs,  Va., 
September  o,  10,  and  11,  1884. 

(Special  Report  for  Thb  Mkdical  Rbc»kd.) 

Tuesday,  September  9TH — First  Day. 

The  fifteentli  annual  session  of  the  Medical  Society  of 
Virginia  convened  in  the  main  room  of  the  hotel  at  Raw- 
ley  Springs,  Rockingham  County,  Va.,  at  eight  o'clock  on 
Tuesday  evening,  September  9th,  the  President,  Dr.  J. 
Edgar  Chancellor,  of  Charlottesville,  in  the  chair. 

The  meeting  was  opened  with  prayer  by  Rev.  Dr. 
Robert  C.  Mattlack,  of  Philadelphia. 

Dr.  M.  G.  Ellzey,  of  Washington,  D.  C,  in  behalf  of 
the  management  of  the  Springs,  delivered  an  address  of 
welcome,  in  the  course  of  which  he  warmly  greeted  the 
delegates,  and  referred  to  the  fact  that  the  doctors  of 
Virginia  could  better  recommend  to  their  patients  the 
mineral  waters  of  the  State  after  personal  inspection  of 
them  at  the  native  springs. 

Dr.  J.  E.  Chancellor,  President,  for  the  Society, 
made  a  few  appropriate  remarks  in  reply,  and  in  behalf 
of  the  members  present  thanked  the  Springs  manage- 
ment for  the  hospitable  welcome  they  had  already  re- 
ceived. 

Dr,  Robert  I.  Hicks,  of  Fauquier  County,  then  read 
the  address  to  the  public  and  the  profession,  entitled 

HYGIENE    IN   RELATION  TO  THE   PRIVATE   FAMILY. 

He  began  by  showing  the  important  relations  existing 
between  individual  sanitation  and  the  public  health.  He 
briefly  described  the  investigations  of  Pasteur,  Koch, 
and  Devaine,  in  connection  with  the  germ  theory,  ex- 
plaining the  microbes,  bacilli  vibrios,  and  spores  found 
by  these  observers  in  different  forms  of  disease,  and 
warned  his  hearers  not  to  be  too  ready  of  belief  as  to 
these  micro-organisms  producing  disease,  as  they  may  be 
simply  accompanying  the  disorders  in  question.  After 
this  question  is  fairly  settled,  there  yet  remains  the  most 
important  thing  to  be  done,  1.^.,  how  to  best  destroy 
them.  He  enumerated  the  different  hiding-places  of 
these  germs,  and  showed  that  by  destroying  the  condi- 
tions that  make  and  support  them  we  can  in  that  way  do 
best  in  practical  hygiene.  He  said  that  while  these 
agents  do  exist,  and  their  existence  is  as  yet  unavoid- 
able, it  is  a  further  fact  that  we  are  responsible  for 
them  to  a  much  greater  extent  than  we  are  willing  to  ad- 
mit. Many  are  chargeable  to  ignorance  and  reckless- 
ness. He  showed  how  some  of  the  preventable  diseases 
are  produced  simply  from  people  not  having  a  knowledge 
of  the  primitive  points  of  practical  hygiene.  Public  leg- 
islation, while  in  every  way  desirable,  can  do  little  else 
than  establish  general  quarantine  laws  against  the  great 
plagues,  but,  except  in  a  general  way,  it  cannot  enter 


into  the  private  house,  it  cannot  reform  the  domestic 
habits,  it  cannot  enforce  purity  in  a  private  well,  and  as 
these  things  involve  the  life  and  health  of  the  family, 
they  must  be  attended  to  from  within.  As  nations  are 
but  aggregations  of  individuals,  as  is  the  individual  so  is 
the  nation.  Toulon  and  Marseilles  are  now  paying  the 
terrible  penalty  of  individual  uncleanliness. 

The  happiness,  longevity,  and  often  the  success  itsell 
of  man,  is  largely  dependent  upon  an  intelligent  recogni- 
tion of  the  laws  of  health.  Misery,  disease,  and  failure 
in  life  are  the  penalties  paid  for  their  violation.  Penalties 
extending  beyond  one  generation  are  frequently  the  re- 
sult of  personal  neglect.  Our  present  knowledge  of 
pathology  shows  us  that  diseases  are  often  perverted  life 
processes,  and  are  therefore  more  easily  prevented  than 
stamped  out  when  once  begun. 

Dr.  Hicks  showed  a  firm  belief  in  the  preventability  of 
consumption,  and  did  not  think  it  hereditary  to  anything 
like  the  commonly  accepted  extent  Out  of  one  hundred 
cases  in  New  York  only  twenty-six  per  cent,  were  hered- 
itary, the  remainder  (seventy-four  per  cent.)  are  charged 
to  damp  air,  insufficient  food,  poverty,  and  filth.  He 
wished  to  impress  upon  his  hearers  the  fact  that  tubercle 
is  not  a  new  formation  dependent  upon  hereditary  taint^ 
but  is  merely  an  alteration  of  normal  nutrition,  a  de- 
graded tissue  resulting  from  neglect  of  trivial  complaints 
in  connection  with  a  disregard  of  ordinary  sanitation. 
He  illustrated  these  and  other  points  by  cases  drawn 
from  his  private  practice.  He  classed  Bright's  disease, 
dyspepsia,  gout,  etc.,  as  preventable  diseases,  due  fre- 
quently to  personal  habits.  No  organ  can  continue 
sound  and  be  the  constant  carrier  of  morbid  products. 
The  remedy  for  this  class  of  complaints  consists  in  change 
of  habits,  moderation,  etc.  The  subject  of  the  location 
of  the  family  house  and  its  bearing  upon  the  health  of 
its  inmates  was  taken  up  and  carefully  discussed,  the 
point  being  also  illustrated  by  cases  under  his  own  obser- 
vation. He  pronounced  pure  air  antiseptic,  showing,  by 
well-chosen  illustrations,  its  influence  on  animal  life.  He 
thought  that  from  1,200  to  2,000  cubic  feet  of  air  must 
pass  through  a  room  every  two  or  three  hours  to  make  it 
healthy  for  one  individual.  The  addition  of  one  other 
person  impairs  its  purity  and  renders  it  unfit  for  use.  It 
becomes  not  only  unhealthy  but  unclean.  He  took  up 
the  subject  of  ventilation,  and  gave  some  practical  hints 
regarding  it.  He  called  the  attention  of  his  hearers  to 
the  fact  that  dry  heat  was  the  only  perfect  disinfectant,  ex- 
treme cold  having  failed  in  that  direction  in  many  in- 
stances. The  importance  of  light,  both  to  the  well  and 
sick,  was  touched  upon,  and  practical  examples  were 
given  from  his  own  observation.  He  then  showed,  from 
cases  in  his  own  practice,  how  typhoid  fever,  diphtheria, 
and  some  other  diseases  were  often  caused  by  the  pres- 
ence of  old  rubbish,  bad  water,  and  filth.  He  believed 
that  certainly  in  decaying  animal  matter,  and  probably 
also  in  decaying  vegetable  matter,  are  found  the  germs 
that  produce  zymotic  diseases.  The  thorough  destruction 
of  these  matters  insures  the  destruction  of  the  germs.  As 
one  person,  by  bad  personal  habits,  may  not  only  pro- 
duce disease  in  himself  but  pass  it  on  to  others,  the  in- 
nocent suffering  with  the  guilty,  each  individual  should 
feel  the  great  responsibility  resting  upon  himself.  He 
concluded  by  showing  the  economical  side  of  the  sanitary 
question,  proving  how  much  could  be  saved  by  personal 
attention  to  the  first  principles  of  hygiene,  and  demanded 
a  higher  grade  of  education  for  the  children  of  to-day  in 
matters  pertaining  to  individual  and  home  sanitation. 

At  the  conclusion  of  Dr.  Hicks*  address  the  Secretary 
read  the  names  of  forty-four  physicians  who  applied  for 
admission  into  the  Society,  ^y  vote  the  list  was  referred 
to  the  proper  committee. 

THE    SERIOUS   ILLNESS   OF   HONORARY   FELLOW   DR.    R.    S, 
PAYNE, 

of    Lynchburg,    having   been  announced    by  a    mem- 
ber, the  Secretary  was  directed  to  telegraph  to  him  the 


324 


THE  MEDICAL  RECORD. 


[September  20, 1884. 


resolutions  of  sympathy  adopted  by  the  unanimous  vote 
of  the  Society. 

The  nomination  and  election  of  officers  of  the  Associa- 
tion were  then  taken  up. 

The  evening  session  was  devoted  to  a  consideration  of 

THS   PHYSICIANS  TO   BE   APPOINTED  UPON  THE  BOARD   OP 
MEDICAL   EXAMINERS. 

The  State  is  divided  into  ten  congressional  districts  and 
the  bill  provides  that  the  State  Medical  Society  shall 
nominate  three  men  from  each  district,  and  two  from  the 
State  at  large.  These  names  will  be  presented  to  the 
Governor,  and,  if  satisfactory  to  him,  the  physicians  named 
will  constitute  a  Board  for  the  examination  of  every 
doctor  who  desires  to  practise  medicine  in  Virginia  after 
January  i,  1885.  The  following  named  gentlemen  were 
selected  by  the  Society  as 

EXAMINERS. 

From  the  State  at  large — Drs.  William  C.  Dabney,  of 
Charlottesville,  and  F.  D.  Cunningham,  of  Richmond, 
were  unanimously  elected.  First  Congressional  district 
—Drs.  W.  W.  Douglas,  of  Richmond' County,  O.  B. 
Finney,  of  Accomac  County,  and  S.  W.  Carmichael,  of 
Spottsylvania  County.  Second  district — Drs.  Thomas  B. 
Ward,  of  Norfolk,  L,  Lankfold,  of  Southampton  County, 
and  Jesse  H.  Peek,  of  Hampton.  Third  district — Drs. 
R.  Lewis,  of  Richmond,  C.  R.  Cullen,  of  Hanover 
County,  and  O.  Crenshaw,  of  Richmond.  Fourth  dis- 
trict— Drs.  Hugh  Stockdell  and  J.  H.  Claiborne,  of 
Petersburg,  and  Dr.  William  J.  Harris,  of  Black's  and 
White's,  Nottaway  County.  Fifth  district—Drs.  Rawley 
Martin,  of  Pittsylvania  County,  William  L.  Robinson, 
of  Danville,  and  T.  B.  Greer,  of  Franklin  County.  Sixth 
district — Drs.  H.  Gray  Latham,  of  Lynchburg,  Harvey 
Black,  of  Blacksburg,  and  Oscar  Wiley,  of  Roanoke 
County.  Seventh  district—Drs.  William  P.  McGuire,  of 
Winchester,  J.  H.  NeflF,  of  Rockingham  County,  and 
Hugh  T.  Nelson,  of  Albemarle  County.  Eighth  district 
— Drs.  Alexander  Harris,  of  Jeffersonton,  C.  C.  Conway, 
of  Orange  County,  and  Bedford  Brown,  of  Alexandria. 
Ninth  district—Drs.  S.  W.  Dickinson  and  R-  D.  Huffard, 
of  Smyth  County,  and  Robert  J.  Preston,  of  Washington 
County.-  Tenth  district — Drs.  Merriwether,  of  Amherst 
County,  Z.  G.  Walker,  of  Rockbridge  County,  and  H. 
Patterson,  of  Highland  County. 


Wednesday,  September  ioth — Second  Day. 

Dr.  William  C.  Dabney,  of  Charlottesville,  as  chair- 
man, read  the 

report  of    the    COMMnTEB   ON   MEDICAL   LEGISLATION, 

in  the  course  of  which  he  referred  to  the  work  done 
during  the  meetings  of  the  Legislature  in  the  past  few 
years,  closing  with  showing  the  success  the  committee 
met  with  in  the  last  legislature,  an  act  providing  for  a 
Board  of  Medical  Examiners  having  been  then  passed. 
Although  the  bill  finally  passed  was  not  exactly  what  the 
profession  desired,  still  it  was  far  in  advance  of  no  act 
at  all  for  the  protection  of  the  people  of  the  State.  The 
committee  was  discharged  with  the  full  thanks  of  the 
Society. 

Dr.  L.  B.  £dwards,  of  Richmond,  then  read  for  Dr. 
H.  T.  Nelson,  of  Charlottesville,  the  report  on 

advances    in   anatomy    AND    PHYSIOLOGY, 

and  after  making  excellent  references  to  what  had  been 
done  in  this  line  in  the  past  few  years,  he  began  his  re- 
port by  showing  the  newer  discovered  morphological 
components  of  the  blood,  and  referred  to  the  late  exam- 
inations of  this  fluid  made  by  German  and  Italian  scien- 
tists, mentioning  their  beliefs  in  thrombosis,  etc. 

The  next  subject  taken  up  was  the  physiology  of  diges- 
I'on,  and  the  writer  spoke  of  the  newer  theories  concern- 


ing peptones.  All  the  tissues  of  the  body  contain  some 
digestive  power,  according  to  one  observer.  Albumen 
and  peptone  are  identical,  if  we  are  to  believe  some 
authorities.  According  to  Dr.  Frank,  of  New  York, 
animals  fed  on  peptones  were  nourished  in  the  same  man- 
ner as  if  fed  on  albumen.  The  favorable  views  of  Dr. 
Jacobi  on  peptone  feeding  were  quoted  with  great  praise. 
The  subject  of  the  intracranial  nerve-system  was  taken 
up,  and  the  writer  confined  his  remarks  mainly  to  the 
sensory  portion  of  the  encephalon,  taking  occasion  to 
remark  that  there  had  not  recently  appeared  any  addi- 
tions to  our  existing  knowledge  of  the  cerebral  motor 
centres  and  their  connections.  He  closed  by  expressing 
the  hope  that  his  paper  might  have  some  practical  bear- 
ing upon  alimentation  in  disease,  and  might  encourage 
more  general  study  of  cerebral  pathology,  a  more  per- 
feet  knowledge  of  which  must  ultimately  increase  the 
longevity  of  our  race. 

The  President,  Dr.  J.  E.  Chancellor,  then  delivered 
his  annual  address,  taking  as  his  subject 

A     BRIEF     REVIEW     OF     THE     ORIGIN     AND     HISTORY    OF 
MEDICINE. 

After  a  few  introductory  remarks  he  began  by  con- 
gratulating the  Society  upon  the  great  and  growing  inter- 
est so  evidently  manifested  in' the  yearly  meetings,  as 
evidenced  by  the  large  attendance  last  year,  and  the  sdll 
larger  attendance  of  members  this  year,  about  one  hun- 
dred and  twenty-five  being  |  present  The  character  of 
the  papers  presented  had  also  improved  of  late  years. 
He  mentioned  especially  the  great  work  done  by  the  So- 
ciety members,  in  securing,  since  the  last  session,  a  par- 
tial recognition  of  the  rights  of  the  profession,  by  Legis- 
lative enactment,  in  the  passage  of  the  Anatomy  Bill 
and  the  act  establishing  a  State  Board  of  Medical  Ex- 
aminers, but  also  said  that,  gratifying  as  this  fact  may  be, 
there  yet  remains  much  to  be  done  by  the  proper  authori- 
ties. With  his  words  of  greeting  he  said  was  mingled 
the  always  sad  duty  of  presenting  to  the  Society  the  tid- 
ings of  the  work  of  death  among  the  membership  during 
the  past  year.  It  had  seemed  to  have  been  a  year  of  tin- 
usual  mortality,  among  the  elder  members  espedallj. 
Six  or  eight  of  the  charter  members  have  died  since  the 
last  meeting,  and  several  of  the  younger  Fellows.  Three 
of  those  taken  from  the  Society's  work  were  ex-presidents, 
and  one  a  distinguished  professor  in  the  Medical  College 
of  Virginia.  The  speaker  paid  a  brief  tribute  to  the 
memories  of  the  departed  members,  and  referred  in 
touching  terms  to  the  memory  of  our  beloved  Honorazj 
Fellow,  Dr.  J.  Marion  Sims,  calling  him  the  Moses  of 
our  profession,  as  well  as  the  father  of  gynecology  in 
America. 

He   then  passed  to  the  consideration  of  his  subject 
proper,  saying  that  the  central  and  all-absorbing  thought 
of  the  world  of  medicine  was  progress — scientific  prog- 
ress^  the  development  of  a  more   advanced  medical 
education,  and  a  higher  standard  for  graduation.    The 
advance  in  medical  science  has  been  so  rapid,  and  the 
glamour  thrown  around  the  medical  study  of  to-day  was 
so  great,  that  there  was  danger  that  the  work  in  its  de- 
velopment done  by  the  earlier  fathers  of  medicine  would 
be  overlooked     He  would  like  to  call  a  halt  in  this,  and 
ask  the  members  present  to  review  with  him  briefly  the 
origin  and  history  of  ancient  medicine.     He  then  pro- 
ceeded from  his  standpoint  to  show  that  with  the  crea- 
tion of  our  first  ancestors  the  necessity  for  the  healing 
art  originated,  and  he  proceeded  to  unfold,  step  by  step 
with  the  progress  of  ages,  its  growth  into  a  science.    He 
first  took  up  the  medicine  of  the  patriarchs,  following  it 
up  through  centuries  to  the  sacerdotal  S3rstem  or  that  of 
the  priesthood,  and  in  what  manner  these  had  led  to  the 
present  distinctly  professional  system.    He  plainly  showed 
that  medicine  had  an  organized  existence  nine  hundred 
years  before  Hippocrates — the  generally  accepted  "Father 
of  Medicine'* — and  perhaps  even  beyond  tliis.     He 
quoted  Herodotus  to  show  the  expedients  commonly  re- 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


325 


sorted  to  in  the  earlier  days  of  science,  the  recording  of 
cases  treated,  and  remedies  used,  by  writing  on  the  walls 
of  ancient  temples,  etc  The  president  then  went  on  to 
describe  the  systems  of  medicine.  He  began  with  the 
Ayar  Veda,  or  sacred  revelations  of  the  Hindoo  system, 
and  then  spoke  of  the  Greek  system,  fully  elaborating 
the  subject.  The  Roman  and  Israelitish  systems  of 
medicine  were  fully  brought  into  review,  and  the  entire 
portion  of  the  paper  relating  to  these  systems  showed 
great  research  and  much  familiarity  with  the  matters  re- 
ferred to.  He  also  gave  an  interesting  account  of  the 
Ebus  papyrus,  found  at  ancient  Memphis  about  ten  years 
ago.  He  referred  to  this  "hermetic  book  of  medica- 
ment "  now  to  be  seen  at  Leipsic,  and  said  that  it  showed 
diagnoses  made,  remedies  suggested,  and  systematic 
treatment  of  diseases  about  1600  B.C.  He  then  traced 
the  origin  and  progress  of  medicine  in  Egypt,  and  how  in 
after  years  it  was  first  introduced  into  Rome,  bringing  it 
down  to  the  time  of  Hippocrates.  He  spoke  of  the 
origin  of  the  medical  school  at  Alexandria  and  those  of 
Cridnos,  which  gave  rise  to  the  Cridnerian  lectures,  etc. 
After  this  he  took  up  the  history  of  those  men  who  were 
roost  prominent  under  the  different  systems  of  the  practice 
of  medicine  in  the  olden  time. 

He  referred  to  the  importance  of  properly  organizing 
and  of  selecting  the  proper  men  who  should  be  placed 
apon  the  Board  of  Medical  Examiners  for  the  State,  to 
be  appointed  during  the  session,  urging  the  society  mem- 
bers to  make  it  a  thoroughly  independent  body.  He, 
although  praising  the  work  of  the  committee,  did  not  by 
any  means  look  upon  the  act  constituting  a  Board  of 
Examiners  as  it  now  stands,  to  be  exactly  what  the  pro- 
fession desired,  and  suggested  the  appointment  of  a 
committee  to  recommend  amendments  to  the  bill  as 
seemed  necessary.  He  took  up  the  subject  of  the  State 
Board  of  Health,  and  showed  how  ridiculous  such  a 
board  was  made  by  the  fact  that  no  money  is  given  it  by 
the  State  to  do  any  work  with,  it  consequently  being  with- 
out efficiency,  and  in  fact  a  nullity.  Lastly,  he  lu-ged  that 
steps  should  be  taken  to  secure,  as  soon  as  possible,  a  full 
history  of  the  deceased  medical  men  of  the  State  of  Vir- 
ginia, as  it  certainly  was  the  duty  of  the  present  genera- 
tion to  rescue  from  oblivion  the  galaxy  of  illustrious 
names  which  have  been  emblazoned  upon  the  honorable 
page  of  medicine  in  Virginia. 


Thursday,  September   iith — Third  Day. 

The  morning  session  opened  at  9.30  o'clock,  Thurs- 
day, and  the  regular  business  of  the  Society  was  pro- 
ceeded with.  After  the  reading  of  letters  from  non-resi- 
dent honorary  fellows,  etc.,  and  work  of  like  nature.  Dr. 
J.  M.  Toner,  of  Washington,  was  unanimously  elected  an 
honorary  fellow  of  the  Society. 

Dr.  S.  B.  Morrison,  of  Rockbridge  County,  presented 
resolutions  of 

RESPECT  TO  THE  MEMORY   OF   DR.  J.  MARION   SIMS, 

one  of  the  most  prominent  fellows,  which  were  unani- 
mously adopted  by  a  rising  vote. 
Dr.  S.  B.  M(^8on  then  read  his  report  on 

ADVANCES     IN    OBSTETRICS     AND     DISEASES     OF     WOMEN 
AND   CHILDREN. 

He  began  by  running  over  the  case  of  pregnant  women, 
and  not  only  referred  to  the  familiar  truths  of  obstetrics, 
but  from  his  own  practice  illustrated  many  of  his  points. 
He  protested  against  too  much  interference  with  the 
physiological  process  of  child-bearing,  and  thought  that, 
as  a  mle,  the  less  duty  the  accoucheur  felt  called  upon  to 
perform  the  better  for  the  patient  He  instanced  the 
ease  with  which  the  Indians  of  this  country  went  through 
this  most  natural  work.  He  referred  to  the  use  and 
abuse  of  ergot  and  chloroform,  and  fully  mentioned  the 
proper  method  of  employing  massage  and  expression. 
Forceps,  he  thought,  were  invaluable,  and  he  pronounced 


decidedly  in  favor  of  the  use  of  the  instrument.  He  be- 
lieved fully  in  Denman's  rule,  that  when  the  ear  of  the 
child  can  be  plainly  felt  in  the  lower  strait  the  forceps 
should  be  employed.  Uterine  haematocele  in  pregnant 
women  was  touched  upon,  and  the  reader  presented  a 
case  from  his  own  practice  illustrative  of  this  condition. 
He  referred  to  the  common  occurrence  of  gynecological 
disorders,  and  in  reporting  some  of  his  own  cases  illus- 
trated the  points  made  in  his  paper. 

He  particularly  made  reference  to  the  fact  that  an 
early  treatment  should  be  employed  in  instances  of  the 
kind,  and  laid  down  the  rules  he  was  in  the  habit  of 
adopting  in  like  cases.  Batte/s  operation  he  thought 
would  not  stand  the  test  of  time.  He  was  very  desirous 
that  a  school  for  nurses  should  be  established  in  Virginia. 
On  conclusion  of  the  paper,  several  members  made  a  few 
remarks  concerning  the  views  presented. 

Dr.  John  Clopton,  of  Williamsburg,  presented,  through 
another  member,  his  paper  upon 

ADVANCES   IN   PSYCHOLOGY.  AND    NEUROLOGY, 

which  was  simply  an  apology  for  not  preparing  a  full 
report. 

Dr.  George  D.  Harrison^  of  New  York,  by  invita- 
tion, read  a  paper  upOn 

the  modern  treatment  of  wounds. 

He  considered  the  subject  very  fully,  detailing  the  work 
of  micro-organisms  on  the  living  tissue.  He  made  a 
clear  statement  of  the  necessary  procedure  to  produce 
an  antiseptic  condition  of  wounds  which  had  taken  on 
suppurative  action.  His  method  in  operations  was,  first 
to  keep  the  wound  in  an  aseptic  condition  until  the  dress- 
pgs  were  applied,  and  second,  to  put  on  the  dressings  in 
such  a  manner  that  the  wound  will  remain  aseptic.  He 
detailed  all  the  processes  of  cleanliness  which  were  to  be 
employed  in  such  instances;  how  the  instruments, 
sponges,  operator's  hands,  drainage-tubes,  sutures,  etc., 
should  be  treated  to  render  them  aseptic.  Lister's  full 
dressing  was  described.  He  was  favorably  inclined  toward 
the  use  of  iodoform.  He  said  that,  according  to  Von 
Minewarter,  the  healing  process  after  the  use  of  the  Lis- 
ter method  was  decidedly  shorter  in  point  of  time,  and 
that  he  fully  believed  in  the  same  mode.  He  thought 
the  day  of  that  terrible  bugbear  of  surgery,  septicaemia, 
was  about  past,  and  that  if  operators  would  fully  adopt 
the  clean  method  of  treating  wounds  favorable  results 
would  be  more  frequent.  He  concluded  by  paying  an 
eloquent  tribute  to  those  men  of  great  scientific  renown, 
Pasteur  and  Lister. 

Dr.  Hunter  McGuire  made  some  practical  remarks 
upon  wounds  and  their  treatment,  and  gave  most  excel- 
lent advice  concerning  cleanliness  in  operations  in  private 
practice. 

Dr.  G.  S.  Stone,  of  Loudon  County,  Dr.  S.  B.  Mor- 
rison, of  Rockbridge  County,  Dr.  J.  H.  Neff,  of  Harrison- 
burg, Dr.  Wm.  L.  Robinson,  of  Danville,  Dr.  J.  E. 
Chancellor,  of  Charlottesville,  Dr.  I^.  Lankford,  of 
Southampton  County,  Dr.  Alban  S.  Payne,  of  Atlanta, 
Ga.,  Dr.  R.  Tatum,  of  Harrisonburg,  Dr.  Jessie  Ewell, 
Sr.,  of  Prince  William  County,  and  Dr.  H.  M.  Patterson, 
of  Highland  County,  discussed  the  subject. 

The  next  paper  read  was  presented  by  Dr.  Alexander 
Harris,  of  Jefferson  ton,  Va.,  on 

the  medicinal  properties  and  therapeutic  applica- 
tion OF  the  waters  of  FAUQUIER  WHITE  SULPHUR 
SPRINGS,  VA. 

The  reader  purposed  to  give  a  careful  and  rational 
explanation  of  the  medicinal  properties  and  therapeutic 
application  of  this  water  through  its  chemical  constitu- 
tion. The  springs  being  at  such  an  elevation — about 
seven  hundred  feet  above  sea  level — the  hygienic  sur- 
roundings of  the  hotel  and  grounds  are  unsurpassed,  this 
being  plainly  evidenced  by  the  fact  that  the  writer  has 
not  been  called  upon  to  treat  a  case  of  zymotic  disease 
which  had  its  origin  on  the  premises  during  his  thirty-five 


326 


THE   MEDICAL  RECORD. 


[September  20,  1884. 


years'  connection  with  the  springs.  The  water  is  remark- 
able for  its  lightness  and  possesses  a  very  strong  sul- 
phurous taste  and  smell.  The  quality  of  lightness  enables 
Che  patients  residing  at  the  springs  to  ingest  nearly  twice 
as  much  in  quantity  than  if  it  were  an  ordinary  freestone 
water.  The  experience  of  Dr.  Harris  and  others  has 
shown  the  water  to  be  primarily  diuretic,  diaphoretic,  or 
purgative,  and  secondarily  alterative  and  tonic.  It  gives, 
when  first  tasted,  a  perceptible  stimulant  eflfect,  in  some 
cases  causing  a  sense  of  fulness  of  the  head,  in  some  few 
cases  going  so  far  as  to  produce  headache.  The  reason 
for  the  remarkable  therapeutic  properties  possessed  by 
this  water  can  be  readily  seen  by  a  careful  examination 
of  an  analysis  of  it.  There  are  nearly  three  grains  of 
iron  phosphate,  lime,  and  magnesia  in  the  gallon,  and  it 
can  be  understood  how  the  tired  brain  is  rested  and  the 
overworked  nervous  system  is  built  up  by  the  use  of 
these  waters.  The  reader  then  compared  the  analysis  of 
this  water  with  the  analyses  of  1 78  of  the  most  important 
and  best  known  natural  mineral  waters  of  this  country 
and  Europe,  and  showed  how  rarely  the  ferric  phosphates 
were  to  be  found  in  those  waters — there  being  only  two 
of  this  number  which  have  an^  of  this  salt  in  solution, 
namely,  the  water  under  discussion  (containing  two 
grains  to  the  gallon),  and  the  Newbury  (two-fifths  of  a 
grain  per  gallon).  It  can  be  readily  understood  how 
broad  a  range  of  therapeutic  application  the  Fauquier 
White  Sulphur  waters  possess  in  those  cases  of  chronic 
diseased  action  dependent  upon  loss  of  nerve-power. 
Not  only  did  Dr.  Harris  draw  upon  his  own  record  of 
practice  for  illustrative  cases,  but  referred  to  Burke's 
work  on  the  Virginia  Springs  for  a  number  of  instances 
where  these  waters  had  done  so  much  good.  The  use  of 
this  water,  according  to  Dr.  Harris,  is  especially  valuable 
in  dyspepsias  of  neurotic  origin,  in  dropsies,  in  certain 
instances  of  neurasthenia,  etc. 

The  third  day's  afternoon  session  began  at  three  o'clock 
Thursday,  nth  inst.,  with  the  report  of  Dr.  H.  W.  Clark- 
son,  as  chairman  of  the  delegation  from  the  Society  to 
the  last  session  of  the  American  Medical  Association. 

The  committee  appointed  to  report  upon  the 

THERAPEUTIC  VALUE  OF  RAWLEY  SPRINGS  WATER, 

made  a  return  through  the  chairman.  Dr.  T.  M.  Miller, 
of  Frederick  County.  In  his  paper  he  entered  into  a 
full  analysis  of  the  water,  and  compared  it  with  that  of  the 
most  noted  and  best  visited  springs  of  this  and  other 
countries.  The  especial  point  in  Rawley  water  which 
renders  its  therapeutic  properties  so  valuable  is  the  large 
quantity  of  protoxide  of  iron  placed  in  complete  solution 
by  the  excess  of  carbonic  acid  contained  therein.  The 
iron  being  rapidly  appropriated  by  the  red  corpuscles  of 
the  blood,  the  anaemic  patient  who  uses  the  water  is 
soon  put  into  a  condition  where  proper  assimilation 
takes  place.  The  water  abounds  in  carbonates,  not  only 
of  iron,  but  also  of  all  the  common  alkalies  to  the  ex- 
clusion of  the  sulphate. 

Dr.  F.  M.  Robertson,  of  Charleston,  S.  C,  by  in- 
vitation of  the  Society,  also  read  a  paper  upon  the  same 
subject,  the  medicinal  virtues  of  Rawley  Springs  water, 
in  the  course  of  which  he  very  highly  extolled  its  eflFects. 

Drs.  George  \  \  arrison,  of  New  York  City,  and  F.  M. 
Robertson,  of  Charleston,  S.  C,  by  unanimous  vote  of 
the  Society,  were  made  non-resident  Honorary  Fellows. 

Dr.  Chancellor  then  yielded  the  chair  to  his  successor. 
Dr.  S.  K.  Jackson,  of  Norfolk,  and  was  unanimously 
elected  an  Honorary  Fellow  of  the  Society. 

The  following  summer  resorts  extended  invitations  to 
the  Society  to  hold  its  session  of  1885  at  their  hotels ; 
Rawley  Springs,  of  Rockingham  County ;  Alleghany 
Springs,  of  Montgomery  County. 

It  was  decided  by  vote  to  meet  at  Alleghany  Springs 
in  the  fall  of  1885. 

A  unanimous  vote  of  thanks  for  the  extreme  kindness 
and  hospitality  extended  this  year  to  the  Society  by  the 
Rawley  Springs  management  was  passed,  the  manage- 


ment entertaining  the  members  free  of  all  hotel  charge 
during  the  session. 

Dr.  Hunter  McGuire  then  presented  his  paper  upon 

intestinal  obstruction — its  differential  diagnosis. 

He  began  by  relating  some  illustrative  cases,  which 
showed  the  necessity  of  making,  as  far  as  possible,  an 
early  and  positive  diagnosis,  for  the  purpose  of  operating 
if  necessary.  Yet  he  had  seen  patients  recover  entirely 
with  but  little  or  no  treatment.  He  gave  the  different 
modes  of  production  of  this  condition,  and  showed  how 
operative  treatment  often  offered  great  prospect  of  re- 
covery. The  paper  was  mainly  confined  to  the  diag- 
nosis of  this  difhculty.  He  had  seen  a  patient  die  in 
thirty-six  hours,  and  had  also  seen  others  which  recovered 
thoroughly  after  a  complete  condition  of  obstruction. 
He  laid  down,  as  a  rule,  the  fact  that  no  purgative  should 
be  given  at  first.  This  he  considered  one  of  the  most 
important  points  to  be  remembered.  He  looked  upon 
opium  as  the  sheet-anchor  in  these  cases.  He  criticised 
most  unfavorably  several  of  the  older  methods  of  treat- 
ment. He  showed  when  he  thought  was  the  proper 
time  for  opening  the  abdomen,  namely  in  certain  cases, 
in  thirty-six  hours  after  the  proper  medicinal  treatment 
had  been  faithfully  tried. 

etherization  by  the  rectum. 

Dr.  William  H.  Coggeshall,  of  Richmond,  Va.,  then 
read  a  paper  upon  this  subject,  and  showed  that  the 
method  was  by  no  means  a  new  advance  in  therapeutics, 
but  simply  a  revival  of  the  process  of  Pirogoff,  who  em- 
ployed it  in  1848,  a  year  after  the  discovery  of  ether  an- 
aesthesia. The  writer  traced  the  employment  of  the 
rectal  process  down  to  about  thirty  years  ago  and  showed 
that  no  clinical  record  had  been  made  of  its  use  since 
then,  until  M.  Mollidre  wrote  his  first  paper  for  the 
Lyons  Mhdicale^  in  March  last,  explaining  that  Dr.  Axel 
Iversen,  of  Copenhagen,  had  called  his  attention  to  it, 
and  referred  to  six  successful  cases  by  this  method.  Dr. 
Coggeshall  presented  the  details  of  &fty  cases  where  rec- 
tal anaesthesia  had  been  employed,  this  number  being 
all  he  could  find  fully  detailed  in  the  American  medical 
journals  of  this  year,  one  or  two  occurring  in  his  own 
practice.  He  found  from  examination  of  the  cases  re- 
ported that  by  this  process  the  preliminary  stage  of  ex- 
citement in  anaesthesia  is  certainly  of  shorter  duration 
than  when  the  vapor  is  inhaled.  There  is  also  less  vom- 
iting, but  it  may  occur  at  an  unexpected  time  during  the 
operation.  The  question  as  to  whether  the  return  to 
sensibility  after  this  method  is  quicker  than  when  inhala- 
tion is  used  he  thought  to  be  doubtful.  The  great  ele- 
ment of  danger,  however,  and  the  reason  why  rectal  ether- 
ization will  never  come  into  general  use,  is  because  of 
the  liability  of  the  mucous  membrane  of  the  lower  bowel 
to  take  on  inflammatory  action  from  the  presence  of  the 
ether  vapor.  Two  fatal  cases  were  given  by  the  writer 
out  of  the  fifty  reported,  making  four  per  cent,  of  deaths. 
He  gave  the  fullest  instructions  for  the  employment 
of  this  method  when  it  was  required,  as  in  face  and 
mouth  operations,  and  described  his  own  form  of  home- 
made apparatus  for  rectal  anaesthesia,  which  could  easily 
be  improvised  by  any  doctor  even  away  from  the  city. 
The  several  important  points  insisted  upon  for  the  use 
of  ether  vapor  per  rectum  were  as  follows :  The  lower 
bowel  should  be  thoroughly  cleansed  by  enemata  before 
the  introduction  of  the  rectal  tube ;  the  connecting- 
jetnts  of  the  tube  and  tubing  must  be  perfect ;  the  tub- 
ing should  be  about  two  feet  long  ;  the  water-bath  should 
be  kept  as  nearly  as  possible  at  the  ?ame  temperature — 
120®  to  140°  F.  ;  the  rectal  tube  should  be  withdrawn 
when  insensibility  is  complete  ;  the  nates  should  be  held 
tightly  together  by  an  assistant ;  the  possibility  of  sud- 
den peristalsis  occurring  during  the  operation  should  be 
provided  for.  The  doctor  concluded  by  advising  only 
those  to  experiment  with  this  method  who  could  afibrd 
to  take  some  risk. 


September  20,  1884.  J 


THE  MEDICAL  RECORD. 


Z'il 


The  Society  by  vote  thanked  Dr.  Coggeshall  for  his 
painsuking  collection  of  cases  of  this  method. 

Dr.  Wiluam  G.  Rogbrs,  of  Charlottesville,  then,  as 
cbainnao,  read  the  report  of  the  committee  appointed 
last  session  to  secure  legislation  against  the  practice  of 
druggists  refilling  prescriptions  containing  narcotic  poi- 
sons without  the  renewal  order  by  a  physician.  Al- 
though the  Committee  worked  hard  for  it  the  bill  was 
not  passed  by  the  Legislature  last  winter. 

The  evening  session  opened  at  7.30  o'clock,  Dr.  Sam- 
USL  K.  Jackson,  President,  in  the  Chair,  with  the  read- 
ing of  an  excellent  paper  by  Dr.  M.  A.  Rust,  of  Rich- 
mond, on 

TYPHOID    FSVBR. 

The  reader  went  rapidly  over  the  pathology  of  the  dis- 
ease, showing  the  tissue  changes  he  believed  to  occur. 
He  spent  some  time  in  defining  this  particular  fever,  and 
made  a  strong  protest  against  calling  the  fever  which  is 
now,  and  has  been,  endemic  in  Richmond,  a  form  of 
'*tjpho-malarial  fever,"  as  he  thought  that  such  a  combi- 
nation did  not  exist.  He  looked  upon  it  as  a  special 
grade  of  enteric  fever,  which  might  be  called  a  by-name 
for  typhoid.  He  thought  the  special  germs  producing 
malarial  fever  and  typhoid  fever  never  became  blended 
in  any  one  case — ^in  fact  that  it  was  impossible  for  such 
blending  to  occur.  He  endeavored  to  show  that  typhoid 
fever  was  a  distinctly  defined  disease,  whether  severe  or 
light  in  character,  having  a  truly  personal  character  of 
itself  which  could  never  be  mingled  with  that  of  any 
other.  His  treatment  for  this  disorder  was  mainly  cold 
sponge  bathing,  sulphate  of  quinia,  bismuth,  beef-tea, 
and  wine,  and  he  had  great  faith  in  milk  as  the  main  ar- 
ticle of  diet.  He  recommended  that  the  milk  be  always 
boiled  for  use. 

Dr.  Alban  S.  Paynb,  of  Atlanta,  Ga.,  non-resident 
Honorary  Fellow,  next  read  a  paper  on 

CEREBRO-SPINAL  MENINGITIS. 

He  began  by  saying  that  as  he  had  so  often  met  with 
cases  of  cholera  morbus  and  cholera  infantum  which 
could  not  be  differentiated  from  cerebrospinal  meningitis, 
he  would  make  a  few  remarks  upon  the  disease  known 
as  cholera  infantum.  His  remarks  concerning  menin- 
gitis were  very  apt,  and  were  attentively  listened  to  by 
the  members.  He  had  found  the  monobromide  of  cam- 
phor to  be  very  valuable  in  treating  these  diseases.  He 
blisters  the  nape  of  the  neck  with  croton-oil,  and  usu- 
ally gives  a  hot  mustard  bath.  Quinine  should  be  given 
at  night  or  morning,  and  he  was  in  the  habit  of  giving 
chlor-anodyne  to  control  pain. 

Dr.  I.  S.  Stone,  of  Loudon  County,  then  read  a  paper 
upon  the  use  of 

MASSAGE    AND     ELECTRICITY    IN   HYSTERIA   AND  ALLIED 
DISORDERS, 

from  the  point  of  view  of  the  general  practitioner.  He  went 
over  some  of  the  forms  of  hysteria  and  neurasthenia,  and 
related  his  success  in  sevend  such  cases.  He  was  a  firm 
believer  in  the  theory  and  practice  of  Dr.  Weir  Mitchell, 
and  thought  he  had  in  several  instances  improved  in  some 
degree  the  methods  adopted  by  that  celebrated  specialist 
He  showed  how  the  ordinary  country  practitioner  could 
successfully  handle  this  class  of  cases,  and  illustrated  the 
points  mentioned  by  two  or  three  very  severe  cases  of 
nervous  disease.  Seclusion,  he  thought,  was  one  of  the 
best  helps  in  treatment,  especially  in  female  patients,  as 
the  constant  attendance  of  visitors  to  see  and  talk  with 
the  patient  that  "  has  such  strange  symptoms  and  so 
bodiers  the  doctors,''  certainly  does  an  enormous  amount 
of  injury.  He  beheved  in  the  vahie  of  a  skim -milk  diet 
in  these  cases,  and  he  also  used  quantities  of  raw  beef 
made  into  a  broth,  after  the  method  of  Weir  Mitchell. 

At  ia3o  o'clock  the  Society  was  invited  by  the  Raw- 
ley  Springs  management  to  a  very  handsome  complimen- 
tary banquet  'Hie  embossed  menus  were  engraved  and 
printed  for  this  special  occasion,  the  tables  were  deco- 
lated  with  flowers,  etc.,  and  the  wines  were  excellent    It 


was  a  remarkable  affiaiir  to  have  been  gotten  up,  off  in 
the  country^  eleven  miles  from  the  railroad. 

Friday,  September  i2TH — Fourth  Day. 
The  fourth  day's  session  convened  at  9.30,  Friday 
morning,  by  Dr.  J.  N.  Upshur  opening  the  discussion 
on 

MALARIAL   FEVER, 

by  reading  a  paper  prepared  on  the  subject  by  Dr.  R.  B. 
Storer,  of  Richmond.  The  writer  began  with  a  history 
of  miasma,  presenting,  up  to  the  present  year,  all  that  is 
known  on  this  branch  of  the  subject  He  then  went 
into  the  causation  of  this  condition,  and  referred  especi- 
ally to  the  fact  that  in  Richmond,  for  the  past  ten  years, 
whenever  the  streets  have  been  torn  up  for  the  purpose 
of  putting  in  new  culverts,  etc.,  fever  has  invariably  fol- 
lowed the  excavations.  He  also  mentioned  the  fact  that 
in  that  city  there  are  certain  portions  where  fever  has 
followed  the  introduction  of  water  from  a  certain  part  of 
the  water-supply  canal,  when  the  other  districts  of  the 
city  have  been  entirely  free  from  it.  He  showed  that 
this  was  the  case  even  where  chemical  analysis  and 
microscopical  examination  failed  utterly  to  show  any- 
thing wrong  with  the  water. 

Dr.  J.  N.  Upshur,  of  Richmond,  then  presented  a 
paper  on 

MALARIAL  FEVER  AS  IT  OCCURRED   IN  RICHMOND  IN  THE 
SPRING  AND  SUMMER  OF    1 884. 

He  called  special  attention  to  the  fact  that  fever  of 
this  type  occurred  generally  in  other  parts  of  Virginia  as 
well  as  in  Richmond.  The  type  of  fever  presented  some 
peculiarities  different  from  that  ordinarily  seen.  No 
doubt  the  cause  of  the  fever  was  entirely  atmospheric. 
It  will  be  remembered  by  the  local  profession  that  there 
was  a  great  deal  of  rain  during  the  spring  and  early  sum- 
mer. The  reader  had  noticed  on  several  occasions  at 
nighty  and  it  was  remarked  by  others,  that  there  was  a 
most  peculiar  odor  in  various  parts  of  the  city.  It  is 
manifest  that  the  water  could  have  been  no  element  in  the 
production  of  the  fever,  for  the  reason  that  if  it  had  con- 
tained the  germs  of  infection,  the  disease  would  have 
attacked  all  ages  and  all  parts  of  the  city  alike,  there  be- 
ing little  difference  in  the  constitution  of  the  water  whether 
it  comes  from  the  canal,  or  the  river,  or  from  the  old  or 
new  reservoir.  The  subjects  of  the  fever  were  mainly 
young  people.  Another  fact :  the  fever  prevailed  in  other 
parts  of  the  State  where  the  inhabitants,  it  may  be  in- 
ferred, drank  well-water,  and  not  James  River  water. 
The  march  of  influenza  and  epizootic  disease  is  an  an- 
alogous fact  The  disorder  prevailed  from  the  first  of 
May  to  the  middle  of  June.  The  malarial  influence 
during  the  present  summer  has  been  apparent  in  all  the 
prevalent  acute  diseases.  The  doctor  draws  strong  con- 
clusions from  the  analysis  of  the  drinking-water  by  Dr. 
Wm.  H.  Taylor,  State  analyst,  which  has  been  recently 
published  in  the  Richmond  newspapers.  Finally,  all  of 
the  conditions  of  the  weather  were  favorable  to  the  pro- 
duction of  a  malarial  disease.  An  interesting  feature  of 
the  fever  was  the  coolness  of  surface  when  the  thermom- 
eter indicated  a  high  range  of  temperature.  The  doctor 
reports  several  cases  as  illustrative  of  the  features  of  the 
fever,  one  of  which  is  of  special  interest  from  the  fact 
that,  neither  the  mouth  nor  bowel  being  available  at  the 
period  of  greatest  prostration,  the  patient  was  kept  up 
by  systematic  stimulation  by  means  of  the  subcutaneous 
injection  of  brandy.  This  patient  recovered.  Dr.  Upshur 
also  called  especisd  attention  to  the  presence  of  epigastric 
pain  as  a  symptom  diagnostic  of  malaria  in  children. 

Dr.  William  L.  Robinson,  of  Danville,  then  read  a 
paper  upon 

TVPHO-MALARIAL  FEVER 

as  it  has  occurred  in  his  section  of  the  State  during  the 
past  ten  or  twelve  years.  He  presented  the  symptoms 
of  the  fever,  and  showed  that  he  was  correct  in  describ- 
ing it  as  peculiar.     It  seemed  to  differ  from  the  same 


328 


THE   MEDICAL  RECORD. 


[September  20,  i884^ 


class  of  disorder  occurring  in  other  sections,  and  de- 
manded a  different  form  of  therapeutic  application  from 
that  commonly  employed.  The  writer  thought  that 
quinine  was  given  too  often  in  large  doses  in  this  condi- 
tion, and  remarked  that  he  had  never  had  an  abscess 
from  the  use  of  this  salt  when  employed  hypodermically, 
although  he  frequently  gave  it  in  this  manner. 

Dr.  Thomas  J.  Moore,  of  Richmond,  then  delivered  a 
short  and  practical  speech  on  the  general  points  involved 
in  the  causation,  diagnosis,  and  treatment  of 

MALARIAL   F]^VER. 

He  showed  that  no  spot  was  safe  from  the  attacks  of  this 
disease,  and  that  wherever  heat,  moisture,  and  decay- 
ing vegetation  existed  it  would  almost  invariably  be 
found.  He  spoke  of  the  value  of  drainage,  and  that 
malaria  could  be  driven  away  mile  by  mile  by  a  proper 
system  of  the  kind.  He  gave  his  personal  experience 
in  cases  of  malarial  haematuria  which  he  had  so  frequently 
met  with  in  North  Carolina.  He  rapidly  went  over  the 
different  conditions  under  which  this  disease  (malaria) 
was  usually  found,  showing  the  varying  types.  He  rec- 
ommended as  treatment  for  malarial  fever  what  had  been 
empirically  found  best  adapted  for  this  condition  in  each 
certain  section,  except  that,  early  and  always,  quinine 
should,  of  course,  be  employed.  He  decidedly  preferred 
to  administer  the  salt  hypodermically,  and  thought  that 
abscesses  would  be  less  frequently  met  with  if  the  needle 
was  boldly  pushed  into  the  cellular  tissue,  and  the  solu- 
tion not  thrown  into  the  skin.  He  gave  some  excellent 
advice  about  how  to  make  up  the  solution,  so  that  the 
quinia  should  not  only  be  perfectly  dissolved,  but  that 
the  liquid  should  not  have  an  acid  reaction.  He  was  also 
impressed  very  favorably  with  the  action  of  Warburg's 
tincture.  In  connection  with  the  hypodermic  injection 
of  quinia,  he  had  found  that  the  addition  of  a  small  dose 
of  morphia  to  each  injection  was  of  great  value  in  cer- 
tain conditions  of  malaria. 

The  speaker  spoke  directly  to  the  point  and  was  listened 
to  with  the  closest  attention. 

The  President,  Dr.  S.  K.  Jackson,  made  a  few  re- 
marks upon  some  of  the  points  raised,  and  especially 
recommended  the  milk  diet  in  typhoid  fever.  He  was 
absolutely  opposed  to  all  starchy  foods.  He  had  at 
times,  when  using  maltine,  been  able  to  allow  the  patient 
to  take  a  little  of  that  class  of  food.  He  made  great  use 
of  strong  beef- tea,  and  usually  kept  the  patient  on  nothing 
but  the  latter  liquid  and  milk  through  the  course  of  the 
illness. 

Drs.  Stone,  Moore,  Upshur,  and  Rust  discussed  the 
subject  of  malaria,  but  no  novel  views  were  presented. 
A  great  difference  of  opinion  was  manifest  regarding  the 
question  as  to  whether  typho-malarial  fever  was  a  distinct 
disease. 

A  paper  by  Dr.  E.  E.  Field,  of  Norfolk,  entitled 

yellow  chills, 
was  read  by  title. 

Dr.  William  Selden,  of  Norfolk,  was  elected  an 
Honorary  Fellow  of  the  Society,  and  a  considerable 
amount  of  routine  business  was  transacted. 

Dr.  Joseph  A.  White,  of  Richmond,  then  presented 
a  paper  entitled 

SOME     RSBIARKS   ABOUT  CATARACT,   WITH   A    REPORT    OF 
FIFTY-TWO  CASES. 

After  speaking  of  the  mistakes  often  made  in  confound- 
ing other  eye  troubles  with  cataract,  by  careless  pracri- 
tioners,  some  of  which  are  ludicrous  and  some  serious  in 
their  tragical  results,  he  gave  a  short  history  of  the  oper- 
ation of  "  extraction  "  with  the  various  modifications  it 
has  undergone.  He  advocated  strongly  the  performance 
of  iridectomy  as  increasing  the  chances  of  a  successful 
result,  in  opposition  to  the  recent  tendency  of  the  French 
school  to  return  to  Daniel's  method,  also  showing  its 
advantages  as  a  preliminary  operation  in  certain  cases, 
as  it  divides  and  diminishes  the  traumatism.     He  gave 


an  account  of  Foster's  operation  of  "  trituration  of  the 
lens"  for  ripening  cataract,  with  a  reference  to  some 
cases  of  his  own,  but  considered  that  it  has,  like  all  other 
surgical  operations,  its  attendant  risks,  and  is  as  yet  only 
on  probation.  After  some  remarks  on  the  opening  of 
the  capsule,  he  passed  to  a  consideration  of  the  cases 
operated  on  in  Richmond  during  the  past  four  and  a  half 
years — fifty-two  in  number.  There  were  no  failures  in 
cases  under  seventy  years  of  age,  and  only  two  over 
seventy  years,  as  a  result  of  the  traumatism.  Another 
patient  lost  his  eye  after  recovery,  from  septic  infection 
of  both  eyes,  by  a  sponge  used  by  a  hospital  attendant, 
setting  up  purulent  ophthalmia.  Anaesthesia  was  used  in 
eleven  cases  only,  and  the  most  serious  accidents  during 
the  operation,  which  occurred  in  nine  cases,  he  attributed 
to  the  vomiting  induced  by  the  anaesthetic  He  uses 
anaesthesia  only  in  very  timid  or  cowardly  patients,  be- 
cause there  is  very  little  pain  from  the  operation  if  he  can 
trust  to  the  statements  of  those  operated  upon.  In  regard 
to  antisepsis  in  cataract  operations,  he  thinks  that  it  is 
quite  suf^cient  to  see  that  the  most  scrupulous  cleanli- 
ness before  and  during  the  operation  is  observed,  especi- 
ally of  all  the  instruments  employed.  He  uses  instruments 
as  little  as  possible,  and  after  the  iridectomy  does  away 
with  the  blepharostat  and  uses  the  lids  and  his  fingers  to 
remove  the  lens.  In  regard  to  the  secondary  operation  of 
cutting  the  capsule  he  considered  it  of  great  importance  as 
increasing  the  visual  acuteness  and  lessening  the  chances 
of  subsequent  reaction  about  the  capsule  and  iris,  and 
instanced  a  case  in  point  where,  from  neglect  of  this  pre- 
caution, a  patient  with  good  vision  lost  the  eye  eighteen 
months  after,  the  trouble  starting  in  the  capsule,  which 
had  gradually  thickened  and  wrinkled,  ending  in  irido- 
capsulitis  and  cyclitis.  Dr.  White  concluded  his  paper 
with  a  full  report  of  a  case  of  some  physiological  interest 
as  exemplifying  the  accepted  theory  of  vision.     A  man 


named  Daniel  F- 


of  Weldon,  N.  C,  had  become 


blind  with  double  cataract  when  seven  years  of  age,  was 
educated  in  an  asylum  for  the  blind,  and  was  operated 
on  in  Richmond,  Va.,  when  thirty-two  years  old.  The 
result  was  perfect  vision  in  both  eyes.  He  could  judge 
nothing  of  the  shape  of  an  article  until  he  touched  it  He 
could  not  locate  objects  in  space,  and  invariably  miscal- 
culated the  distance  when  reaching  for  anything.  He 
was  afraid  to  walk  about  because  he  could  not  judge  of 
the  height  or  depth  of  anything  in  his  way — such  as  gut- 
ters or  curbstones.  In  fact  he  was  less  independent 
when  he  first  recovered  vision  than  before  he  was  oper- 
ated upon. 

It  was  decided  that  the  subject  of  **  Scarlet  Fever  *' 
should  be  the  one  for  general  discussion  at  next  year's 
meeting,  and  Dr.  Thomas  J.  Moore,  of  Richmond,  was 
appointed  to  read  the  first  paper  on  the  subject 

The  Society  then  adjourned  sine  die. 

Altogether  the  session  oi  1884  was  the  best  one  ever 
held  by  the  Society,  the  papers  read  were  in  the  main 
valuable  and  practical,  the  attendance  the  laigest  in  the 
history  of  the  Association,  there  being  between  125  and 
250  members  registered  as  present,  and  over  sixty  new 
members  were  elected. 

The  following  are 

THB   OFFICERS   ELECTED   FOR    1884-85  : 

/y^xiV/^/— Dr. Samuel  K.  Jackson,  of  Norfolk;  First 
Vice-President — Dr.  Jesse  Ewell,  Sr.,  of  Hickory  Grove, 
Prince  William  County ;  Second  Vice-President — Dr.  Ben- 
jamin Blackford,  of  Lynchburg ;  Third  Vice-President— 
Dr.  Robert  I.  Hicks,  of  Casanova,  Fauquier  County; 
Recording  Secretary — Dr.  Landon  B.  Edwards,  of  Rich- 
mond, Va,;  Corresponding  Secretary — Dr.  Hugh  Taylor, 
of  Richmond,  Va. ;  Trecuurer — Dr.  Richard  T.  Styll,  of 
Richmond,  Va, ;  Executive  Committee — Dr.  W.  W.  Par- 
ker, of  Richmond  (Chairman),  Drs.  Harvey  Black,  Fran- 
cis D.  Cunningham,  John  Herbert  Claiborne,  and  L. 
Ashton ;  Committee  on  Publication — Drs.  E.  T.  Robinson, 
C.  W.  P.  Brock,  and  George  Ross. 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


329 


EIGHTH   SESSION. 
Held  at  Copenhagen^  Denmark^  August  10-16,  1884. 

REPORTS   OF   SECTIONS. 
SECTION  OF  OBSTETRICS  AND  GYNECOLOGY. 
Prof.  KoEBERLfi,  of  Strasburg,  read  a  paper  on  the 

TREATMENT  OF  UTERINE  MYOMATA  BY  LAPAROTOMY. 

The  indications  for  the  operation  were  :  the  gravity  of 
the  state  of  the  patient  in  consequence  of  excessive  or 
prolonged  catamenial  hemorrhage,  or  from  the  rapid  or 
continued  increase  of  the  tumor,  and  from  the  age  of  the 
patient,  from  the  seat  of  the  tumor,  by  the  particular 
circumstances,  as  when  life  became  unsupportable  from 
the  troubles  caused  by  the  tumor.     Operation  was  contra- 
indicated  when  there  were  extensive  vascular  adhesions 
to  the  abdominal  walls,  or  when  the  too  extended  tumor 
had  too  extensive  connections  ;  when  it  was  enclosed  in 
the  pelvis  ;  when  there  was  ascitic  effusions  liable  to  in- 
crease, and  to  reproduce  them  quickly ;  or  when  there 
was  some    concomitant   incurable    affection,    or   some 
circumstances    which    might    exercise   an    unfavorable 
influence   in   recovery.     The   operative   method  varied 
according  to  tlie  seat  and  size  of  the  tumor.     Uterine 
fibro-myomata   should  be  operated   on  by  the  vaginal 
method  in  cases  where  they  formed  a  more  or  less  pro- 
nounced swelling  in  the  uterine  cavity  and  toward  the 
vagina,  when  the  size  of  the  canal  thus  allowed  extrac- 
tion in  this  way.     Fibro-myoma,  projecting  into  the  ex- 
treme cavity,  and  immovable  by  the  genital  canal,  as 
well  as  interstitial  and  sub-peritoneal  tumors  were  cap- 
able of  removal    by  laparotomy.     Professor  Koeberl6 
spoke  on  hysterotomy  and  hysterectomy,  and  gave  the 
general  rules  for  their  operation.     He  stated  the  result 
was  very  favorable  when  the  tumors  were  developed  in 
the  body  of  the  uterus.     The  operation  was  difficult  and 
grave  when  the  tumors  were  developed  in   the  broad 
ligaments,  and  deeply  imbedded  in  the  pelvic  cavity. 
The  reunion  of  the  abdominal  wound,  dressing,  and  anti- 
septic treatment    were    next    passed   in    review.     Dr. 
Koeberl6   concluded  his  paper  by   affirming  that  the 
treatment  of  uterine  fibro-myomata  by  laparotomy  con- 
stituted a  real  progress  in  contemporary  surgery,  and 
merited  in  every  way  serious  considerations. 

This  communication  was  well  received  and  discussed 
by  Sir  Spencer  Wells,,  of  London,  Dr.  Margary,  of  Turin, 
and  Dr.  Apostoli,  of  Paris. 

ELECTRIC  TREATMENT  OF  UTERINE  MYOMATA. 

Dr.  Apostoli,  of  Paris,  proposed  a  new  electrical  thera- 
peusis  for  uterine  fibromata,  distinguished  by  its  point  of 
application,  nature,  intensity,  and  its  manual  mode  of  ap- 
plication. To  the  old  procedure  'of  the  application  of 
continuous  currents  to  the  cure  of  fibrous  tumors — char- 
acterized :  (i)  by  very  feeble  electrical  intensity  ;  (2)  by 
the  vagina  bemg  oftenest  the  point  of  application  of  the 
positive  pole — he  opposed  a  treatment  always  more 
active,  since  it  reached  100  millimetres  of  intensity,  and 
was  always  intrauterine,  acting  along  the  whole  depth 
and  extent  of  the  uterine  mucous  membrane.  A  clinical 
experience,  extending  over  two  years,  upon  over  one 
hundred  cases,  had  shown  that  the  treatment  constantly 
reduced  the  size  of  the  uterus,  and  completely  restored 
the  patient. 

DESTRUCTION     OF    UTERINE     TUMORS     BY    ELECTROLYTIC 
PUNCTURE. 

Dr.  P.  Meniere,  of  Paris,  advocated  the  destruction 
of  uterine  tumors  by  electrolytic  puncture.  This,  he 
aid,  constituted  an  operation  which  was  effectual  and  of 
little  danger,  provided  that  it  were  practised,  not  by  the 
vagina,  but  across  the  abdominal  wall.     It  was  indicated 


— (i)  when  medical  treatment  had  failed  ;  (2)  where  the 
fibromas  were  very  large,  and  also  only  slightly  movable ; 
(3)  when  they  endangered  the  life  of  the  patient  by  con- 
tinuous metrorrhagias  or  grave  general  trouble  ;  (4)  it 
was  a  final  resource  in  cases  where  total  removal  wa^ 
impossible.  This  operation  had  already  been  practised 
by  Cutler  in  187 1,  Broure  in  1873,  Kimbal  in  1874,  Cini- 
salli  in  1875,  ^"^  Semeleder  in  1876.  But  their  opera- 
tive procedures  differed,  were  very  vaguely  described, 
and  little  known  in  Europe.  In  face  of  the  marvellous 
results  which  he  had  got  in  six  cases,  the  results  of  which 
were  indelibly  fixed  in  his  memory,  it  seemed  to  him  to 
be  of  interest  and  useful  to  call  the  attention  of  the  Con- 
gress to  this  point  of  gynecological  therapeutics,  and 
particularly  to  the  manual  method  of  procedure,  on 
which  he  had,  after  numerous  trials,  finally  settled.  The 
instruments  employed  were  :  (i)  a  battery  of  the  contin- 
uous current  of  Gaiffe,  with  twenty-four  pairs  of  zinc 
plates,  and  galvanometer  divided  in  milliamperes ;  (2 
gold  needles,  ten  centimetres  long  by  a  millimetre  and  a 
half  thick,  flattened  and  pointed  at  their  extremities  ^o 
lance-shape,  with  cutting  edges)  \  they  were  isolated  for 
a  length  of  seven  centimetres  by  means  of  resinous  var- 
nish, dried  and  calcined  in  the  flame  of  a  spirit-lamp 

(3)  a  needle  propeller,  with  a  graduated  stop-notch,  so 
as  to  insert  the  needles  to  a  depth  previously  fixed  upon  ; 

(4)  light  and  flexible  conducting  wires,  joined  to  the 
needles  by  means  of  a  serves  fines.  The  operation  was, 
he  said,  repeated  twice  a  week,  or  every  ten  days,  in  case 
of  inflammatory  accidents;  the  sittings  lasting  twenty 
minutes  from  the  insertion  of  the  positive  and  negative 
electrodes  the  depth  of  eight  centimetres ;  a  current  of 
from  forty  to  fifty  milliamperes ;  and,  after  the  extraction 
of  the  needles,  the  closing  of  the  cutaneous  orifice  with 
collodion. 

Dr.  Margary,  of  Turin,  advocated  supravaginal  am- 
putation of  the  uterus  from  the  vagina  as  a  treatment  for 
fibromata  in  the  posterior  uterine  wall. 

oophorectomy  as  a  remedy  against  uterine  TUMORS. 

Dr.  Wiedow,  of  Freiburg,  said  that  he  had  collected 
the  cases  in  which  removal  of  the  ovaries  had  been  per- 
formed for  uterine  tumors,  partly  from  published  records, 
partly  from  private  information.  Through  the  friendly 
co-operation  of  a  large  number  of  German,  Austrian,  and 
Swiss  practitioners,  he  was  able  to  arrive  at  conclusions 
as  to  the  lasting  influence  of  the  operations,  and  the  sub- 
sequent condition  of  the  patients  on  whom  it  was  per- 
formed. The  principal  point  was  to  show  the  influence 
of  the  operation  on  the  cessadon  of  hemorrhage,  and  on 
the  diminution  of  the  size  of  the  tumors.  He  also  en- 
deavored to  point  out  whether,  and  in  what  way,  the  re- 
sult of  the  operation  was  modified  by  the  situation  and 
size  of  the  tumor. 

Prof.  Hegar,  of  Freiburg,  and  Sir  Spencer  Wells  took 
part  in  the  discussion  which  followed. 

THE   CiESAREAN   SECTION   AND    ITS    MODIFICATIONS. 

Prof.  P.  Muller,  of  Berne,  read  a  paper  on  this  sub- 
ject. He  said  that  the  prognosis  in  Caesarean  sections 
had  been  hitherto  very  unfavorable,  the  death-rate  ex- 
ceeding eighty  per  cent  'The  recent  advances  in 
surgery,  especially  the  improvements  in  laparotomy,  had 
had  an  influence  on  the  operation,  which  was  shown  by 
the  endeavors  to  successfully  combat  the  loss  of  blood 
and  sepsis.  This  object  was  sought  to  be  attained  by 
two  essentially  different  ways ;  the  modifications  were 
either  radical  or  conservative.  In  the  radical  modifica- 
tions the  source  of  hemorrhage  and  of  septic  infection 
was  cut  off  by  the  uterus,  in  the  conservative  the  uterus 
was  retained  and  an  endeavor  was  made  to  ward  off 
these  dangers  by  careful  treatment  of  the  uterine  wound. 
Both  methods  had  doubtless  certain  advantages,  but 
theoretical  considerations  could  not  support  the  rsidical 
modification.  Yet,  in  tegard  to  this  matter,  the  result 
must  turn  the  scale ;  the  operation  which  was  attended 


330 


THE  MEDICAL  RECORD. 


[September  20,  1884. 


with  the  lowest  mortality  must  be  accepted  as  the  best 
The  death-rate  of  the  radical  operation  was  about  fifty 
per  cent. ;  but  trustworthy  statistics  were  wanting  with 
regard  to  the  conservative  method,  of  which  there  had 
been  as  yet  less  experience  than  of  the  former.  It 
therefore  remained  yet  to  be  decided  which  operation 
should  be  preferred.  If  the  conservative  method  should 
gain  recognition,  another  condition  would  have  to  be  ful- 
filled, namely,  to  protect  the  woman  against  rupture  of 
the  uterus  in  a  subsequent  pregnancy,  and  against  the 
danger  of  another  Caesarean  section  ;  and  this  would 
have  to  be  done  in  a  much  more  satisfactory  and  safe 
way  than  had  hitherto  been  the  case  in  the  Csesarean 
operation. 

INTERMITTENT    CONTRACTIONS    OF    THE    UTERUS    IN   THE 
DIAGNOSIS   OF   PREGNANCY   AND    ITS    COMPLICATIONS. 

Dr.  Braxton  Hicks,  of  London,  presented  a  paper 
on  this  subject,  illustrated  by  three  cases.  He  again 
called  attention  to  the  value  of  this  means  of  diagnosis, 
and  briefly  referred  to  the  discussion  on  his  paper  in  the 
last  Congress,  where  it  was  stated  that  soft  tumors  of  the 
uterus  also  contracted  at  intervals.  Presuming  this  was 
ultimately  found  to  be  correct  in  general,  the  cases  in 
which  this  would  interfere  with  the  diagnosis  were 
pointed  out,  namely,  those  in  which  the  foetus  could  not 
be  felt,  and  where  hemorrhage  was  urgent,  for  instance, 
where  the  uterus  remained  constantly  firm,  as  in  some 
cases  of  blighted  ovum,  apoplectic  ovum.  In  these 
there  was  almost  always  a  history  of  pregnancy,  and  of 
recent  hemorrhage ;  while  if  there  was  amenorrhoea  or 
only  normal  menses,  it  would  be  exceedingly  rare  if  it 
were  a  soft  tumor.  He  gave  three  cases,  two  of  preg- 
nancy complicated  with  uterine  fibromata.  In  the  third 
one,  of  extreme  obliquity  of  the  uterus,  it  was  difficult  to 
say  how  much  was  uterus.  In  all  the  cases,  the  exact 
relation  of  the  uterus  was  clearly  and  readily  made  out 
by  means  of  the  alteration  which  occurred  at  short 
intervals  in  the  density  of  the  uterus, 

antiseptics  in  laparotomy. 

Prof.  Mikulicz,  of  Cracow,  began  by  referring  to 
the  necessity  of  antiseptics  in  laparotomy  as  well  as  in  all 
other  operations  attended  with  loss  of  blood.  The  prin- 
ciples of  the  use  of  antiseptics  in  laparatomy  were  the 
same  as  in  other  great  operations ;  but  the  details  differed 
essentially  in  some  points.  This  depended  on  the  pecu- 
liarities of  the  peritoneum,  which  in  some  respects  favored, 
while  in  others  they  impeded  the  application  of  anti- 
sepsis. The  most  important  properties  of  the  peritoneum 
having  an  influence  in  antisepsis  were,  first,  the  great  ex- 
tent of  surface,  which  was  a  source  of  danger  of  cooling 
on  exposure,  of  rapidly  spreading  inflammatory  and  sep- 
tic processes,  etc. ;  seeing  its  great  power  of  absorption 
and  excitation,  the  first  leading,  in  septic  peritonitis,  to 
general  septic  infection,  while,  in  the  healthy  peritoneum, 
it  prevented  the  accumulation  of  large  masses  of  secre- 
tion ;  thirdly,  the  liability  to  pour  out  plastic  exudations, 
and  to  rapidly  form  firm  adhesions ;  in  this  way,  foci  of 
inflammation  might  be  localized,  and  ligatures  and  sepa- 
rated masses  of  tissue  encapsuled.  With  regard  to  anti- 
sepsis in  laparotomy,  attention  was  directed  to  the  follow- 
ing points :  i.  The  peritoneum  is  more  easily  affected  by 
septic  infective  matters  than  any  other  tissue.  Besides  this, 
it  was  not  possible  to  use,  as  with  wounds  of  other  parts, 
very  active  antiseptic  measures,  such  as  irrigation  with 
carbolic  acid  and  other  powerful  means,  as,  on  account 
of  the  rapid  absorption,  the  danger  of  poisoning  by  the 
antiseptic  was  very  great.  Again,  while  drainage  was  of 
great  use  in  wounds  of  other  parts,  it  was  useless  in  the 
peritoneal  cavity,  and  could  not  obviate  the  results  of  in- 
fection of  any  kind.  For  these  reasons,  the  chief  point 
to  be  attended  to  in  antisepsis  during  laparotomy  was  the 
absolute  withholding  of  septic  ifaaterials  from  the  peri- 
toneum ;  and  herein  lay  the  great  difference  between 


antisepsis  in  laparotomy  and  other  operations.  In  lapa* 
rotomy,  antisepsis  was  pre-eminently  prophylactic.  The 
cleansing  and  disinfecting  of  everything  which  was  to  be 
used  in  or  had  any  relation  to  the  operation  must  be  car- 
ried  out  much  more  thoroughly  than  in  other  operations. 
The  spray  was  superfluous  in  faultlessly  clean  rooms; 
but  in  hospitals  it  should  be  used  for  half  an  hour  to  an 
hour  before  the  operation,  for  the  mechanical  purification 
of  the  air.  During  the  operation  it  was  useless.  In 
operations  on  the  stomach  and  intestines,  the  absolme 
prevention  of  the  escape  of  the  gastric  or  intestinal  con- 
tents was  one  of  the  most  important  points  in  antisepsis. 
Drainage  of  the  peritoneum  was  nearly  always  quite 
superfluous  in  operations  performed  aseptically;  it  might 
even  be  dangerous  to  allow  infection  of  the  periosteum 
to  take  place  through  the  drainage  openings.  Complete 
drainage  of  the  peritoneum  by  the  methods  now  in 
use  was,  on  mechanical  grounds,  altogether  impossible. 
Hence  drainage  was  permissible  in  laparatomy  only 
in  rare  and  exceptional  cases.  2.  Besides  direct  infec- 
tion during  the  operation,  spontaneous  infection  might 
occur  in  the  peritoneum  in  certain  conditions.  It  oc- 
curred when  a  large  quantity  of  fresh,  especially  sero- 
sanguineous  fluid  collected  in  the  peritoneum  and  was 
not  rapidly  absorbed.  In  this  was  developed  bacteria, 
which  led  to  decomposition  of  the  secretion,  and  infec- 
tion of  the  peritoneum.  Hence  the  second  great  prin- 
ciple of  antisepsis  in  laparotomy  was  to  prevent  the  col- 
lection of  secretion  in  the  peritoneal  cavity.  Any  means 
which  limited  the  amount  of  secretion  in  the  peritoneum 
or  favored  its  absorption  was  a  part  of  antisepsis  in  lapa- 
rotomy. An  accurate  *'  toilet  of  peritoneum  "  was  of  the 
first  importance  ;  next  came  the  prevention  of  secreting 
wound-surfaces  in  the  peritoneum  by  various  means, 
such  as  ligature  en  masse^  cauterization  of  the  pedicle 
and  of  adhesions,  suture  of  the  wounded  surfaces,  e,g,^ 
of  the  ligamenta  lata  or  of  the  stump  of  the  uterus  (as 
in  Schroder's  myomotomy),  the  shelling  out  of  tumors 
having  a  wide  base  or  lying  behind  the  periosteum,  fol- 
lowed by  suture  of  the  peritoneal  covering  to  the  abdom- 
inal wound,  so  as  to  shut  off  the  entire  surface  of  die 
wound  from  the  peritoneum.  Everything  also  most  be 
avoided  which  might  too  powerfully  excite  the  perito- 
neum to  secretion  ;  e.g,^  irritation  by  strong  antiseptics. 
To  favor  absorption,  a  compressive  bandage  should  be 
applied  over  the  whole  abdomen ;  it  also  fulfils  the  ne- 
cessary object  of  keeping  the  abdomen  at  rest.  With  re- 
gard to  the  material  used  for  ligature,  catgut  and  care- 
fully disinfected  silk  were  equally  good  from  an  antiseptic 
point  of  view.  The  pedicle  might  be  treated  either  ex- 
traperitoneally  or  intraperitoneally,  so  long  as  the  ab- 
dominal cavity  was  perfectly  closed.  The  manner  in 
which  the  sutures  were  applied  to  the  abdomen  has  no 
influence,  provided  that  the  surfaces  of  peritoneum  were 
properly  united.  Any  special  method  of  dressing  the 
wound  was  of  very  little  importance,  provided  that  no 
drainage-tubes  were  introduced  into  the  abdominal  cav- 
ity. A  narrow  strip  of  material,  rendered  antiseptic,  was 
quite  suflSicient  for  the  dressing  of  the  wound ;  and  for 
this  purpose,  solution  of  carbolic  acid  was  the  best  and 
safest  means.  Large  quantities  of  iodoform  were  dan- 
gerous, on  account  of  the  liability  to  poisoning  ;  but  Dr. 
Mikulicz  had  with  advantage  applied  it  in  very  small 
quantities  to  the  pedicle  and  to  the  sutured  stump  of  the 
uterus. 

international  nomenclature  in  obstetrics. 

Prof.  Simpson,  of  Edinburgh,  submitted  a  report 
on  this  subject,  which  he  had  brought  before  the  Con- 
gress in  London  in  188 1.  At  that  Congress,  a  committee 
had  been  appointed  to  consider  the  matter  and  report  to 
this  Congress ;  but,  practically,  nothmg  had  been  done 
by  the  committee.  The  section  now  reconsidered  the 
matter,  reaflirmed  its  importance,  and  requested  the 
committee  to  go  into  it  sifresh  and  report  to  the  next 
Congress. 


September  20,  1884.] 


THE  MEDICAL  RECORD. 


33^^ 


THE  SIGNIFICANCE    OF    ALBUMINURIA    IN    PREGNANT 
WOMEN. 

Prof.  Halberstma,  of  Utrecht,  in  a  paper  on  this 
sobject,  said,  in  the  first  place,  that  the  facts  observed 
did  not  permit  his  recognizing,  as  the  cause  of  albumi- 
nuria in  pregnant  women,  a  reflex  contraction  of  the 
renal  arteries;  second,  albuminuria  in  pregnant  women 
was  specially  observed  when  there  was  a  want  of  propor- 
tion between  the  size  of  the  gravid  utenis  and  the  ab- 
dominal cavity ;  and,  third,  the  cause  of  albuminuria  in 
pregnant  women  was,  in  the  greater  number  of  the  cases, 
the  tension  and  compression  of  the  uterus. 

SOME  DIAGNOSTIC  DIFFICULTIES  CAUSED  BY  HYPERTROPHY 
OF  THE  CERVIX  UTERI. 

Prof.  Howitz,  of  Copenhagen,  pointed  out  that,  in 
cases  of  hypertrophy  of  the  neck  complicated  by  dila- 
tation of  the  body  and  fundus  of  the  uterus,  special 
symptoms  arose  in  consequence  of  change  of  the  anatom- 
ical relations.  In  cases  of  pregnancy,  especially  in  the 
first  months,  this  condition  gave  rise  to  diagnostic  diffi- 
culties. The  elevated  situation  of  the  uterine  enlarge- 
ment, its  strange  mobility,  its  elastricity  and  situation,  were 
characteristic  guides  in  such  cases.  The  foetal  l^ruif  could 
also  be  heard  sooner  than  ordinary.  A  careful  examination 
by  the  vagina  and  rectum  would  give  precise  information 
as  to  the  exact  condition  of  the  uterus. 

Dr.  Priestley,  of  London,  said  he  had  seen  cases 
yery  analogous  to  those  described  by  Professor  Howitz, 
which  produced,  not  difficulty  in  diagnosis,  but  difficulty 
in  accouchement.  It  was  a  question  well  deserving  of 
consideration,  whether,  in  certain  cases,  some  operative 
measure  might  not  be  adopted. 

THB  OPERATIVE    TREATMENT   OF    EXTRA-UTERINE    PREG- 
NANCY. 

Prof.  Werth,  of  Kiel,  said  that  operation  was  in- 
dicated in  the  early  months  of  pregnancy  when  the 
fcetns,  being  dead  and  lying  in  Douglas'  pouch,  produced 
severe  symptoms  of  incarceration.  On  the  other  hand, 
laparotomy  was  without  object  when  it  was  concluded 
that  rupture  of  the  sac  had  taken  place,  and  experience 
up  to  the  present  time  was  in  favor  of  expectant  treat- 
ment. When  pregnancy  was  more  advanced,  and  the 
embryo  was  alive,  operation  gave  little  prospect  of  sav- 
ing the  child,  and  was  of  unfavorable  prognosis  for  the 
mother,  except  in  cases  where  the  anatomical  conditions 
favored  the  removal  of  the  entire  ovum  with  its  mem- 
branes. Hence  it  was  a  principle  to  avoid  operation 
while  the  child  was  alive,  and  to  wait  for  its  death.  The 
expulsive  movements  following  the  death  of  the  embryo 
could,  as  a  rule,  be  held  in  check  by  appropriate  means. 
As  the  extra-uterine  position  of  a  foetus  which  had  died 
after  having  passed  beyond  the  first  stages  of  develop- 
ment was  a  source  of  danger  to  the  mother's  life,  re- 
moval by  operation  of  the  dead  foetus  was  necessary. 
The  prognosis  was  incomparably  better  than  that  of 
operation  during  the  life  of  the  foetus,  provided  that  a  suit- 
able time  was  chosen  for  the  operation.  This,  whenever 
possible,  should  not  be  performed  before  arrest  of  the 
circulation  in  the  maternal  placenta  might  be  supposed 
to  have  taken  place ;  namely,  from  the  tenth  to  the 
twelfth  week  after  the  death  of  the  foetus.  Speaking  of 
the  methods  of  operation,  Dr.  Werth  said  that,  in  the 
rare  cases  of  prolonged  pregnancy  in  the  outer  part  of 
the  Fallopian  tube  or  in  the  ovary,  with  simultaneous 
imfolding  of  the  broad  ligament,  extirpation  of  the  entire 
sac  was  indicated ;  the  operation  was  like  ovariotomy, 
and  the  prognosis  was  similar.  As  a  general  rule,  the 
sac  should  be  sutured  to  the  abdominal  wound.  The 
placenta  and  membranes  of  the  ovum  should  be  re- 
iQoved,  if  there  was  no  doubt  as  to  the  previous  occlusion 
of  the  placental  sinuses  by  thrombosis.  If  strict  anti- 
septic precautions  were  followed  during  the  operation, 
and  an  occlusive  dressing  applied,  then  neither  prevent- 
ive drainage  through  the  vagina  nor  permanent  irriga- 


tion of  the  sac  was  necessary,  provided  that  decompo- 
sition of  the  contents  of  the  sac  had  not  already  set  in. 
Both  these  were  to  be  avoided,  as  well  as  washing  out 
and  plugging  the  sac  when  the  operation  was  per- 
formed during  the  life  of  the  embryo  or  shortly  after  its 
death,  and  when  artificial  or  spontaneous  detachment  of 
the  placenta  threatened  fatal  hemorrhage.  On  the  other 
hand,  the  author  recommended  in  these  circumstances 
the  partial  filling  of  the  fcetal  sac  with  some  substance 
(tannin  and  salicylic  acid  in  equal  proportions,  accord- 
ing to  Freund),  which  might  enable  the  placenta  to  re- 
main aseptic  until  it  was  thrown  off  at  a  later  date.  Ely- 
trotomy  was  preferable  to  gastrostomy  only  in  some  rare 
and  peculiar  cases.  With  regard  to  the  proceeding  rec- 
ommended by  Martin,  of  partial  removal  of  the  foetal 
sac,  suture  of  the  remaining  part,  and  drainage  through 
the  vagina,  further  experience  was  required  before  a  de- 
cision could  be  arrived  at  as  to  its  general  applicability. 

THE    EARLY   PERFORMANCE   OF   OVARIOTOMY. 

Mr.  Knowsley  Thornton,  of  London,  read  a  paper 
on  this  subject.  He  first  considered  whether  it  was  ever 
right  to  interfere  with  an  ovarian  tumor  by  tapping  or 
by  aspiration.  Spencer  Wells,  Keith,  and  Thomas  were 
in  favor  of  tapping ;  and  many  other  leading  ovariotomists 
encouraged  it.  He  gave  quotations  from  Gross,  Em- 
met, and  Lawson  Tait  against  the  practice  ;  and  referred 
to  the  doubtful  advantages  claimed  for  this  proceeding 
compared  with  its  dangers  and  its  immediate  and  remote 
mortality.  He  said  that  exploratory  incision  was  far 
safer  and  better  in  doubtful  cases.  Tapping  should  be 
condemned,  except  in  some  very  rare  occasions.  He 
would  always  remove  an  ovarian  tumor  as  soon  as  it  was 
large  enough  to  be  abdominal  and  slightly  stretch  the 
parietes.  There  were  objections  to  operating  earlier,  ex- 
cept in  special  cases.  The  danger  was  in  delay.  Patho- 
logical changes  in  the  cysts  might  lead  to  the  escape  of 
their  contents,  and  to  the  formation  of  adhesions ;  or  the 
pedicle  might  become  twisted.  He  adduced  illustrations 
of  the  dangers  of  delay,  drawn  from  over  four  hundred 
ovariotomies  he  had  performed,  including  forty  cases  in 
which  ovarian  fluid  was  free  in  the  peritoneum,  and 
thirty-four  cases  of  twisted  pedicle.  He  then  summed 
up  by  considering  the  following  questions  :  i.  Is  tapping 
ovarian  or  parovarian  cysts,  or  cysts  of  the  broad  liga- 
ment, ever  justifiable  ;  and  if  so,  what  conditions  justify 
it  ?  2.  Can  any  fairly  general  and  defined  rule  be  laid 
down  as  to  the  proper  time  at  which  to  perform  ovari- 
otomy ;  and  if  so,  what  conditions  justify  an  earlier  or 
later  operation  ?  He  concluded  by  appealing  to  the 
profession  to  still  further  improve  the  brilliant  results  of 
ovariotomy  by  condemning  tapping  and  supporting 
early  operation. 

MANAGEMENT   OF  THE   THIRD    STAGE    OF   LABOR. 

Prof.  Stadfeldt,  of  Copenhagen,  read  a  paper  in 
which  he  gave  the  result  of  the  expectant  method  of 
treatment.  Credo's  method,  and  the  Dublin  method.  In 
the  expectant  method,  as  practised  in  Copenhagen,  the 
placenta  was  allowed  to  become  detached  spontaneously, 
and  to  escape  into  the  vagina,  unless  severe  hemorrhage 
indicated  earlier  removal  of  the  contents  of  the  uterus. 
As  a  rule,  the  detachment  of  the  placenta  took  place 
within  about  two  hours.  In  Credo's  method,  circular 
frictions  of  the  fundus  uteri  were  made  immediately  after 
the  birth  of  the  child,  and  during  a  strong  after- pain,  gen- 
erally the  third,  the  placenta  was  press^  out  by  a  com- 
bined concentric  and  pushing  down  pressure  on  the  fun« 
dus  and  body  of  the  uterus.  The  Dublin  method  was 
described  in  somewhat  different  terms  by  different  au- 
thors. As  a  rule,  the  chief  importance  was  attached  to 
pressure  on  the  fundus  uteri  immediately  after  the  birth 
of  the  child.  This,  he  thought,  tended  to  increase  ante- 
flexion, and  thereby  to  impede  the  escape  of  the  placenta* 
He  had,  therefore,  applied  friction  to  the  fundus  uteri,  as 
in  the  first  stage  of  Credo's  method,  and  when  the  placenta 


332 


THE   MEDICAL  RECORD. 


[September  20,  1884. 


had  escaped  into  the  vagina,  it  was  easily  removed 
by  the  help  of  two  fingers,  with  simultaneous  gentle  trac- 
tion on  the  umbilical  cord.  In  a  few  cases,  where  the 
placenta  was  not  expelled  at  the  end  of  half  an  hour,  he 
made  a  depressing  movement  through  the  fundus.  When 
these  methods  failed,  the  placenta  was  removed  by  the 
introduction  of  the  hand  into  the  uterus.  Dr.  Stadfeldt 
liad  treated  a  large  number  of  cases  by  each  of  the  three 
methods  above  named,  and  gave  results.  From  his  sta- 
tistics he  excluded  all  cases  of  abortion  and  of  placenta 
praevia,  cases  in  which  the  contents  of  the  uterus  were 
putrid,  and  some  cases  of  very  difficult  labor.  From 
April  I,  1873, 10  March  31,  1877,  he  followed  the  expec- 
tant method  in  1,780  cases;  from  September  i,  1877,  to 
February  i,  1881,  Cred6's  method  in  1,611  cases;  from 
May  12,  1882,  to  February  15,  1884,  the  Dublin  method 
in  971  cases  ;  and  from  February  16  to  May  30,  188 1,  the 
expectant  method  in  198  cases.  The  results  indicated 
that,  when  compared  with  the  expectant  method,  that  of 
Cred6  was  preferable.  Detachment  and  reunion  of  the 
membranes,  or  of  small  portions  of  placenta,  indeed,  oc- 
curred more  frequently,  but  the  preponderance  was  not 
great  (2,3  against  1.8  per  cent),  and  any  danger  riiight 
be  obviated  by  the  use  of  antiseptics.  On  the  whole,  it 
seemed  to  him  that  the  objectors  to  Credo's  method  were 
wrong  in  attaching  too  much  importance  to  its  disadvan- 
tages, and  overlooking  the  fact  that  it  removed  the  dangers 
attendant  on  the  expectant  method  during  the  time  of  wait- 
ing, especially  outside  lying-in  hospitals.  It  could  not, 
however,  be  denied  that  the  proper  and  safe  application 
of  Credo's  method  required  so  much  intelligence  and  ac- 
curacy that  it  might  be  attended  with  danger  in  the  hands 
of  unskilful  persons,  and,  therefore,  it  was  not  thought 
right  in  Copenhagen  to  teach  it  to  midwives.  On  the 
other  hand,  the  Dublin  method  was  easily  learnt,  and 
was  free  from  the  dangers  of  the  expectant  and  Credo's 
methods ;  on  the  one  hand,  it  diminished  the  danger  of 
flooding  and  of  retention  of  the  placenta ;  and,  on  the 
other,  removed  the  danger  of  separation  and  retention  of 
the  membranes.  It  had  been  said  that  Credo's  Method, 
by  favoring  retention  of  the  membranes  of  the  decidua, 
was  more  liable  than  the  expectant  method  to  give  rise 
to  puerperal  disease  and  mortality.  The  contrary  was 
the  result  in  Dr.  Stadfeldt's  experience ;  the  figures  given 
being,  with  the  expectant  method,  for  disease,  24  per 
cent.,  and  for  mortality,  1.9  per  cent.  ;  with  Credo's 
method,  disease,  18.3  per  cent.,  mortality,  0.6  per 
cent.  In  both  series  antiseptics  had  been  used  with 
equal  energy.  He  believed  that,  in  the  present  day,  re- 
tention of  the  membranes  had  little  influence  on  puer- 
peral disease  and  mortality,  provided  that  strict  antisep- 
tic precautions  were  carried  out  during  labor,  and  that 
the  accoucheur  abstained  from  unnecessary  meddling 
during  the  lying-in  period.  Large  portions  of  decidua 
might  even  be  left  in  the  uterus  without  becoming  septic, 
and  without  giving  rise  to  self-infection  of  the  patient. 

CONGENITAL    LATEROPOSITIONS   OF  THE    UTERUS,  ETC. 

Prof.  Lazarewitsch,  of  Kharkoff,  addressed  the  Sec- 
tion on  the  congenital  lateropositions  of  the  uterus  in 
their  relations  to  the  mechanism  of  labor  and  to  the 
peri-uterine  tumors.  These  congenital  lateropositions 
were,  he  said,  frequent,  especially  those  in  which  the 
uterus  was  completely  displaced  to  the  left.  Those  which 
depended  on  the  development  of  pathological  growths 
must  be  chanced  to  other  positions,  and  on  that  account 
must  be  called  accidental.  But  if  they  depended  on  a 
defect  in  the  development  of  the  broad  ligament,  or  of 
the  lateral  wall  of  thejvagina,  these  positions  were  invari- 
able, and  did  not  alter  during  the  growth  of  the  tumors, 
whatever  these  might  be,  which  were  formed  round  the 
uterus,  any  more  than  during  the  period  of  pregnancy. 
If  the  lateral  position  of  the  uterus  was  sufficiently  marked, 
the  anterior  position  of  the  rectouterine  pouch,  being  dis- 
placed by  the  uterus,  took  an  oblique  shape ;  and  the 
ovary,  which  corresponded  to  the  large  side  of  the  peri- 


uterine space,  being  pressed  upon,  often  lay  above  the 
peri-uterine  pouch,  and  fell  down  more  or  less.  The 
ovary  of  the  opposite  side,  not  finding  place  near  the 
uterus,  was  ordinarily  raised  up  and  passed  above  the  up- 
per entrance  to  the  cavity.  According  as  the  one  or  the 
other  ovary  became  cystic,  the  cyst  either  remained  for  a 
longer  or  shorter  lime  in  the  deep  cavity,  and  in  its  growth 
displaced  the  uterus  forward  and  upward,  or,  from  the  be- 
ginning of  the  growth,  was  found  above  the  deep  pelvis 
and  the  uterus,  leaving  it  free.  If  the  ovary  corresponding 
to  the  large  side  of  the  peri-uterine  space  became  cystic, 
the  pedicle  of  the  cyst  was  ordinarily  long  ;  and  on  the 
contrary,  it  was  short  if  the  cyst  belonged  to  the  ovary 
on  the  smaller  side  of  the  peri-uterine  space.  Thus,  so 
fai'  as  the  lateral  position  of  the  uterus  was  concerned, 
one  was  not  able  to  say  to  which  of  the  ovaries  the  cyst 
belonged  ;  but,  if  one  knew  to  which  ovary  the  cyst  be- 
longed, one  could  estimate  the  length  of  the  pedicle.  Be- 
ing turned  to  one  side,  the  uterus  left  free  entrance  to  the 
recto-uterine  pouch  ;  and,  for  this  reason,  the  blood  of 
the  pouch  could  spread  in  all  directions.  If  the  uterus 
was  turned  to  one  side,  it  was  difficult  to  say  that  it  was 
completely  inclined,  or  bent  forward  or  backward  ;  it  was 
in  this  event  that  the  cases  of  lateroversion  and  latero- 
flexion  were  met  with.  In  the  case  where  the  uterus  was 
turned  to  one  side,  pessaries  could  not  maintain  it,  owing 
to  the  difference  in  the  length  of  the  lateral  walls,  and 
the  different  heights  or  ;  lateral  arches  of  the  vagina. 
One  was  often  deceived  as  to  the  origin  of  the  pain  felt 
sometimes  on  one  side  in  the  lower  part  of  the  abdomen, 
particularly  during  menstruation,  in  attributing  this  to 
the  ovary.  This  pain  most  often  proceeds  from  the  lat- 
erally displaced  womb.  The  congenital  lateropositions, 
as  well  as  the  lateroversions  of  the  womb,  had  an  evident 
influence  on  the  mechanism  of  labor,  but  this  influence 
was  not  proportional.  In  the  lateroversion  the  womb, 
increasing  during  pregnancy,  preserved  its  regular  form, 
changing  only  the  direction  of  its  axis ;  whereas,  when 
displaced,  in  the  lateroposition,  it  preserved  the  direction 
of  its  axis  but  changed  its  shape,  because,  on  the  side  on 
which  it  approaches  one  of  the  lateral  walls  of  the  pelvis, 
its  lower  segment  did  not  expand,  or  expanded  very  little, 
while  the  segment  on  the  opposite  side  underwent  the 
sacciform  expansion.  During  labor  one  could  easily  do 
away  with  the  lateroversion  of  the  womb  by  making  the 
woman  assume  a  suitable  position,  or  by  keeping  up,  by 
means  of  the  hands,  the  corresponding  side  of  the  womb. 
But  these  measures'  became  useless  if  the  womb  was  in 
the  state  of  lateroposition.  In  this  case,  it  was  enough 
to  introduce  the  finger  into  the  neck  of  the  uterus,  and 
to  draw  it  toward  the  middle  of  the  pelvis. 

STATISTICS   OF   PUERPERAL    FEVER   IN    DENMARK. 

Dr.  £.  Ingerslev,  of  Copenhagen,  read  a  paper  in 
which  he  gave  a  brief  summary  of  a  research  into  puer- 
peral mortality  in  the  towns  of  the  Danish  provinces  and 
in  Copenhagen  for  the  •last  seventeen  years.  The  prin- 
cipal aim  of  the  paper  was  to  explain  how  the  difference 
between  the  mortality  in  the  maternities  and  outside 
of  them,  elsewhere  brought  into  such  strong  relief,  had 
lost  its  raison  (Pitrey  since  it  was  proved  that  the  antisep- 
tic measures  to  be  taken  in  labor  were  still  less  per- 
formed outside  of  maternities.  He  also  stated  his  opinion 
that  matters  were,  up  to  this  time,  nearly  as  successfully 
managed  in  the  towns  as  in  the  country  districts  of  Den- 
mark. Dr.  Ingerslev  went  on  to  show  the  ravages  of 
puerperal  fever  were  most  manifest  when  one  looked  at 
the  proportion  between  the  puerperal  mortality  and  the 
total  mortality  in  women  from  fifteen  to  forty-five  years 
of  age,  that  was  to  say,  of  the  age  at  which  labor  gener- 
ally took  place.  In  this  regard,  a  great  resemblance 
was  found  between  this  and  like  researches  made  a  short 
time  back  in  Prussia.  The  great  difficulties  in  the  way 
of  finding  a  fairly  exact  expression  for  the  puerperal  mor- 
tality would  be,  perhaps,  best  overcome  in  a  small 
country,  where  one  could  most  easily  obtain  a  general 


September  20,  1884.] 


THE   MEDICAL   RECORD. 


333 


view  of  things,  and  make  requisite  corrections  by  address- 
ing oneself  to  medical  men  for  the  necessary  explana- 
tions. He  had  made  the  attempt  for  a  period  of  some 
years,  and  in  this  way  had  made  a  calculation  of  the  mor- 
tality as  near  as  possible,  and  showing,  at  the  same  time, 
a  minimum  of  errors.  The  calculation,  so  checked, 
showed  an  evident  decrease  in  the  puerperal  mortality, 
which  undoubtedly  was  due  to  a  more  strictly  antiseptic 
conduct  of  labors  even  outside  the  maternities. 

THE    UTERINE   ADENOLVMPHANGITIS. 

Dr.  Martineau,  of  Paris,  read  a  paper  on  the  above 
condition  "  as  a  cause  of  the  so-called  peri-uterine  troubles 
and  its  importance  for  the  treatment  of  the  inflammation 
of  the  uterus/'  He  took  the  view  that  the  uterine  and 
pcri-uterine  adenolymphangilis  was  closely  connected 
with  uterine  inflammation.  Acute  or  chronic  metritis 
could  not  exist  without  the  uterine  and  peri-uterine  lym- 
phatic system  sharing  in  the  inflammation  of  the  uterine 
tissue.  Peri-uterine  adenolymphangitis  was  the  origin 
of  the  inflammatory  accidents  called  peri-uterine,  such 
as  phlegmon  of  the  broad  ligament,  peri-uterine  phleg- 
mon, perimetritis,  and  pelvic  peritonitis.  The  designa- 
tion of  these  conditions  by  the  names  adenophlegmon  of 
ihe  broad  ligament,  peri-uterine  adenophlegmon,  adeno- 
pclvic  peritonitis,  was  that  which  suited  them,  because  it 
recalled  their  origin  and  pathology.  The  peri- uterine 
adenolymphangitis  being  equivalent  to  uterine  inflamma- 
tion, every  cause  which  would  have  as  a  result  the  in- 
creasing of  this  inflammation  would  at  the  same  time 
increase  the  peri-uterine  adenolymphangitis,  and  bring 
about  the  accidents  of  which  itVas  the  origin.  Adeno- 
lymphangitis, when  there  was  a  question  of  instituting 
local  treatment,  the  treatment  of  the  lesions  of  the  me- 
tritis, gave  the  indication  and  contra-indication  for  the 
treatment,  as  pathogenic  and  nosological  treatment  could 
produce  an  excitation  of  the  uterine  inflammation. 

A  NEW  ELECTRIC  TREATMENT  OF   PERIMETRITIS. 

Dr.  Apostoli  proposed  "  a  new  electric  treatment  of 
perimetritis  by  double  faradization  of  the  uterus."  He 
described,  in  the  first  place,  the  modification  which  he 
had  introduced  in  the  manual  application  of  uterine 
&radization  (A.  Trifner's  method)  ;  and  he  enumerated 
its  general  advantages  in  the  treatment  of  simple  metritis. 
He  applied  his  method  also  advantageously  in  peri- 
metritis,  and  described  the  manual  method,  the  dose, 
duration,  and  intensity  of  the  application.  Summing  up, 
he  had  always  found  the  faradic  currents,  of  high  tension, 
feeble  dose,  and  long  duration,  relieve  every  perimetritis, 
even  acute,  and'  bring  about  its  rapid  resolution. 

TREATMENT   OF   PUERPERAL   FEVER    BY   COLD    BATHS. 

Prof.  Vincent,  of  Lyons,  said :  i.  That  the  ad- 
ministration of  cold  baths  was  practicable  with  the  re- 
cently delivered  attacked  with  puerperal  fever.  2.  That 
cold  baths  were  free  from  danger  in  the*  puerperal  state. 
3.  They  had  a  certain  and  quick  antifebrile  effect  in  the 
sequela  of  delivery.  4.  Recovery  from  puerperal  fever  was 
the  rule  with  treatment  by  baths  of  proper  temperature 
and  methodically  administered.  5.  Cold  baths  were  in- 
dicated in  all  high  temperature  forms  of  after-complica- 
tions of  childbirth,  the  very  acute  peritonitis  excepted. 
The  indication  for  cold  baths  did  not  arise  except  where 
the  fever  was  kept  up,  without  notable  morning  remission, 
to  about  40^  Cent,  when  the  powerlessness  of  quinine 
and  diffusible  stimulants  in  full  doses  had  been  shown, 
and  when,  in  flne,  the  lochias  were  fetid,  and  intra- 
uterine  injections  had  been  carefully  tried  without  bring- 
ing a  fall  in  the  febrile  condition.  6.  Cold  baths  should 
be  administered  at  a  temperature  varying  from  28°  to  18° 
Cent;  according  to  the  fall  secured  by  the  first  bath, 
given  at  28°  or  30°,  the  temperature  of  the  subsequent 
baths  should  be  reduced  (The  rule  was,  to  get  with  a 
coW  or  tepid  bath  a  fall  of  from  one  to  two  degrees  of 
the  patient's  temperature.)  The  method  used  in  typhoid 
fever,  treated  by  cold  baths  after  the  system  of  Dr.  Brand, 


should  be  followed,  with  modifications.  7.  The  cold 
baths  were  repeated  every  three  hours  until  the  tem- 
perature had  fallen  to  38  ,  and  stayed  there,  with  only 
ascending  oscillations  of  some  tenths  in  the  evening. 

8.  When  baths  of  18°  or  20°  repeated  every  three  hours, 
night  and  day,  did  not  bring  about  a  notable  reduction 
of  temperature,  a  large  ice-bag  should  be  placed  in  the 
intervals  of  the  baths,  on  the  abdomen  of  the  patient 

9.  Along  with  the  cold  baths  and  the  ice-bags,  spirits 
and  tonics  should  be  freely  administered  ;  the  patients 
should  be  fed  with  liquid  or  semi-liquid  foods,  having 
much  nutriment  in  a  small  bulk — soups,  beef- tea,  Ameri- 
can broth,  milk,  etc. 

Dr.  Marcy,  of  Boston,  advocated  the  restoration  of 
the  perineum  by  a  new  method ;  and  Dr.  Zambaco,  of 
Constantinople,  submitted  to  the  Section  some  "  Physio- 
logical and  Pathological  Remarks  upon  the  Women  of 
the  East " 


(S^aw&span&enct. 


OUR  LONDON   LEITER. 

(From  our  Special  Correspondent.) 

ALCOHOL  AND  THE  HEALTH  EXHIBITION — DR.  MOXON  ON 
LORD  TENNYSON — ONSLAUGHTS  ON  DOCTORS — SMALL- 
POX AND  VACCINATION — DECREASE  OF  THE  EPIDEMIC. 

London,  August  30,  1884. 

The  Health  Exhibition  continues  to  attract  shoals  of 
visitors.  I  must  confess  that  my  own  experience  of  it 
has  been  very  disappointing.  A  good  many  of  the  ex- 
hibits are  very  interesting  and  some  of  them  instructive, 
but  what  possible  relation  many  of  them  can  be  said  to 
bear  to  the  subject  of  health  I  cannot  say.  Lace-making, 
glove-making,  candle-making,  and  so  on,  are  all  inter- 
esting in  a  way,  but  what  place  have  they  in  a  health  ex- 
hibition ?  The  same  remark  applies  to  the  Chinese  and 
Japanese  Courts— entertaining  as  the  latter  are.  The 
number  of  alcoholic  exhibits  and  the  space  occupied  by 
some  of  them  would  certainly  lead  a  superficial  observer 
to  imagine  that,  in  England,  alcohol  is  a  sine  qua  non  of 
health.  The  "  intelligent  foreigner  "  who  visits  the  Ex- 
hibition, would  perhaps  be  surprised  to  learn  that  there 
are  now  nearly  a  million  of  total  abstainers  in  Great 
Britain,  including  some  hundreds  of  medical  men.  Al- 
though not  an  abstainer  myself,  I  cannot  but  think  that 
the  wholesale  admission  of  alcoholic  exhibits  is  calcu- 
lated to  do  harm.  Their  presence  in  such  an  exhibi- 
tion gives  them  a  position,  so  to  say,  and  people  will  be 
tempted  to  imbibe  alcoholic  drinks  more  freely  than 
heretofore,  because  '*  they  have  been  shown  at  the 
'Health.'"  The  gratuitous  distribution  of  glasses  of 
wine  and  beer  (as  samples)  by  the  exhibitors,  does  not 
look  at  all  well  The  Council  have  at  last  forbidden  it 
as  regards  the  beer,  but  it  still  goes  on  as  regards  the 
wine. 

The  poet-laureate  has  received  the  hardest  blow  I 
should  think  he  ever  had  administered  to  him.  In  the 
current  number  of  The  Lancet^  in  a  most  striking  and 
suggestive  paper  on  the  late  Dr.  Hilton  Fagge,  Dr. 
Moxon  takes  Tennyson  to  task  for  his  foul  libel  on  the 
medical  profession  in  his  volume  of  ballads  published  at 
Christmas,  1880.     I  cannot  resist  quoting  a  piece  : 

**'  Eagge's  greatness  as  a  physician  appeared  in  his  al- 
ways kind  and  sympathetic  and  Christian  treatment  of 
the  sick  poor.  It  is  easy  for  poets  to  put  their  own  de- 
nials of  Christ  into  other  people's  mouths,  and  then  as 
fashionable  authors  to  spread  them  about  on  drawing- 
room  tables.  It  is  convenient  to  be  able  to  work  off 
your  baser  sentiments  in  a  false  character ;  you  yourself 
then  appear  pure  by  contrast  with  your  own  creations. 
But  if  one's  solemn  everyday  duty  is  spent  face  to  face  and 
eye  to  eye  with  the  sorrowing  and  suffering  poor,  one  won- 
ders how  even  a  poet-laureate  could  be  capable  of  think- 


334 


THE  MEDICAL  RECORD. 


[September  20,  1884 


ing  the  matter  of  those  loathsome  lines  of  this  new  peer. 
I  wonder  is  he  yet  ashamed  of  them  ?  What  footing  has 
this  poet  aristocrat  on  any  grounds  of  charity  that  justi- 
fies him  in  putting  his  blasphemous  sentences  into  the 
mouth  of  the  child  he  supposes  ?  Let  him  go  into  a 
children's  hospital,  and  see  how  far  the  poor  sick  little 
ones  think  as  vilely  as  'he  of  the  kind-hearted  doctor, 
whose  only  sorrow  is  that  his  best  help  to  his  little  pa- 
tients too  often  proves  ineffectual.  Fagge  was  physician 
Co  the  Evelina  Hospital  for  Sick  Children.  His  sympa- 
thies were  not  with  grandeur  and  the  House  of  Lords." 

This  is  harsh  but  not  undeserved,  as  those  who  have 
read  through  the  poem  referred  to  will  admit.  Many  of 
our  prolession  are  doubtless  reading  Dr.  Moxon's  denun- 
ciation of  the  laureate  with  keen  appreciation.  The 
whole  of  the  paper  is  well  worth  reading — a  remark  that 
applies  to  all  Dr.  Moxon's  writings. 

The  poet-laureate  is  not  alone  in  attacking  the  pro- 
fession. On  taking  up  a  religious  newspaper  yesterday, 
I  found  a  long  letter  inserted  in  which  a  furious  on- 
slaught was  made  on  doctors  generally,  and  their  treat- 
ment of  hospital  patients  in  particular.  The  same  jour- 
nal stated  some  time  back,  in  an  editorial  on  sanitation, 
that  the  doctors  were  anxious  to  bring  every  one  under 
their  **  tyranny."  Such  thanks  do  we  get  for  trying  to 
check  the  spread  of  disease — a  step  which  directly  tends 
to  impoverish  us. 

I  saw  a  little  time  since  in  a  radical  weekly  journal,  in 
the  course  of  a  controversy  then  raging  in  its  pages  on 
the  subject  of  vaccination,  a  letter  in  which  the  writer 
said  that  doctors  supported  vaccination  because  it  was 
profitable  !  I  was  greatly  tempted  to  write  and  give  the 
obvious  answer,  that  we  certainly  did  not  advocate  vac- 
cination on  that  ground,  as  even  if  it  did  pay,  it  did  not 
pay  a  fractional  part  of  what  small-pox  used  to.  Thirty 
years  ago  it  formed  a  very  important  part  of  a  doctor's 
practice.  Now  many  never  see  a  case.  The  recent 
epidemic,  which  began  to  excite  some  alarm  ^  has  almost 
subsided. 

The  anti-vaccinationists  are  very  active.  At  Leicester 
— one  of  their  strongholds — twelve  hundred  persons  are 
shortly  to  be  tried  for  non-compliance  with  the  Vacci- 
nation Acts. 

OUR  PARIS  LETTER. 

(From  our  Own  Correspondent) 

DR.  BURQ  AND  METALLOTHERAPY — PROFESSOR  BOUCHAR* 
DAT  DOES  NOT  BELIEVE  UNHEALTHY  LODGINGS  SO 
IMPORTANT  A  FACTOR  IN  THE  PATHOGENY  OF  DIS- 
EASE AS  IS  GENERALLY  REPRESENTED — ^A  BLOW  TO 
SANITARIANS — THRIVING  IN  SPITE  OF  DIRT  AND  BAD  AIR 
— HOW  PROFESSOR  BOUCHARDAT  LIVES — PARIS  DRINK- 
ING-WATER UNJUSTLY  ABUSED  —  THE  CHOLERA  IN 
FRANCE. 

Paris,  August  99,  1884. 

Dr.  Burq,  the  founder  of  modern  metallotherapy,  which 
is  also  called  Burqism,  as  you  are  aware,  died  on  the 
1 7  th  inst.  at  Bi^vres,  where  he  had  gone  for  a  holiday. 
He  was  sixty-two  years  of  age.  It  is  not  necessary  for 
me  to  enter  into  the  peculiar  notions  he  held  respecting 
the  action  of  metals  in  the  economy,  particularly  those 
connected  with  the  efficacy  of  copper  as  a  iireventive 
and  curative  agent  for  cholera,  as  th-^y  are  well  known. 
The  theories  which  Dr.  Burq  had  promulgated,  for  the 
first  time  as  far  back  as  1853,  were  brought  to  the 
notice  of  the  Paris  Academy  of  Medicine,  and  although 
his  communication  was  supported  by  Trousseau  and 
Bouchut,  it  was  received  with  little  or  no  favor.  He 
then  retired  almost  into  obscurity,  and  no  more  was 
heard  of  him  till  1877,  when  he  published  a  series  of 
papers  to  the  effect  that  the  application  of  certain  metals 
on  the  skin  determined,  in  anaesthetic  patients,  and  some- 
times in  those  organically  affected,  certain  important 
modifications,  the  principal  being  the  return  of  general 
and  special  sensibility.     Moreover,  he  added,  all  patients 


were  not  sensible  to  the  same  metal,  and  that  gold,  iron, 
and  copper  produced  positive  or  negative  results  accord- 
ing to  the  subjects.  The  experiments  of  Dr.  Burq  were 
verified  by  Professor  Charcot,  at  the  Salpetri^re  Asylum, 
where  this  system  is  frequently  resorted  to ;  but  I  cannot 
say  that  it  has  been  generally  adopted  in  France  or  else- 
where. Like  most  inventors.  Dr.  Burq  did  not  derive 
much  personal  advantage  from  his  discovery,  and  he 
died  almost  penniless. 

Professor  Bouchardat  does  not  consider  unhealthy 
lodgings  so  important  a  factor  in  the  pathogeny  of  dis- 
ease as  is  generally  represented  in  the  profession.  He 
believes  that  this  idea  has  been  greatly  exaggerated,  and 
while  admitting  that,  all  things  being  equal,  people  badly 
lodged  contribute  greatly  to  the  general  mortality,  but 
it  is  only  when  they  are  at  the  same  time  subjected  to 
the  pangs  of  misery — which  are  much  more  terrible — in- 
sufficient and  irregular  alimentation,  excessive  work,  and 
then  alcoholic  and  other  excesses.  In  a  recent  lecture 
at  the  School  of  Medicine,  Professor  Bouchardat  de- 
veloped  the  subject  in  the  following  terms :  "  It  is  cer- 
tain that,  during  the  night,  the  respiratory  organs,  like 
the  other  organs  of  the  body,  perform  their  functions  less 
actively,  and  that  if,  outside  the  hours  of  sleep,  one 
works  moderately  in  the  open  air,  the  health  will  not 
sensibly  suffer  from  the  insalubrity  of  lodgings.  The 
peasants  are  not  better  lodged  than  citizens,  their  food 
is  not  so  good,  and  yet  their  health  is  more  robust. 
Even  among  citizens,  those  who  work  hard,  but  in  the 
open  air,  are  less  susceptible  to  disease  than  the  others." 
M.  Bouchardat  cites  the  example  of  the  chiflfonniers  who 
live  crowded  togetiier  in  huts,  as  less  affected  by  disease 
than  the  average  of  the  working  classes.  The  necessity 
for  pulling  down  unhealthy  lodgings  to  replace  them  by 
palaces  is  not  so  much  felt  as  is  represented,  and  even 
when  all  the  lodgings  are  improved,  the  public  health 
will  not  be  much  influenced  by  it,  so  long  as  the  other 
causes  of  disease  are  in  existence.  The  learned  pro- 
fessor adds  that  it  is  imagined  that  the  privies  and  night- 
soil  are  powerful  causes  of  the  propagation  of  contagious 
diseases  in  large  cities,  an  assertion  offered  gratuitously 
and  without  any  scientific  proof,  and  he  brings  forward 
the  sewer-men  (dgou tiers),  the  night«nien,  and  others  who 
work  in  the  general  deposits  of  night-soil  (d^potoirs),  the 
inhabitants  of ,  Gennevilliers  (just  outside  Paris),  who 
water  their  cultures  with  the  waters  from  the  drains  of 
this  city,  which  are  rich  in  night-soil,  as  not  offering  a 
greater  contingent  of  victims  to  contagious  diseases  than 
those  who  live  more  comfortably.  In  fact,  Professor 
Bouchardat  may  present  himself  as  an  example  of  his 
thesis  in  point,  as  he  lives  in  one  of  the  filthiest  quarters 
of  Parish  in  a  house  he  has  occupied  for  nearly  half  a 
century,  and  yet  he  has  long  passed  his  threescore  and 
ten  without  having  a  day's  illness,  and  he  does  not  recol- 
lect that  the  inhabitants  of  the  little  street  he  is  living  in, 
which  is  a  d^k  dirty  lane  in  the  old  city,  near  the  Ndtre 
Dame  Cathedral,  have  been  more  stricken  with  disease 
than  those  of  til)e  modem  palaces  in  the  Boulevards. 

With  reference  to  the  mortality  of  Paris  being  greater 
than  that  ot  the  other  cities  of  France,  Professor  Bou- 
chardat attributes  this  to  another  cause  :  misery  and  the 
conglomeration  of  unacdimatized  individuals,  who  for 
various  reasons  are  attracted  to  this  city,  and  who  in  the 
case  of  an  outbreak  of  any  epidemic  disease,  are  the  first 
to  be  affected.  The  hospitals  become  crowded  with 
them,  and  it  is  by  them  that  the  mortuary  list  is  swelled. 
It  is  thus  he  explains  the  great  mortality  fix>m  typhoid 
fever  in  Paris,  yet  it  is  not  the  less  true  that  the  causes 
are  local. 

In  the  debate  that  is  being  drawn  out  at  the  Academy 
of  Medicine  anent  the  cholera,  M.  Bouchardat  observed 
that  the  drinking-water  in  Paris  has  been  greatly  and  un- 
justly abused,  particularly  by  foreigners.  He  declared 
that  the  potable  water  distributed  in  Paris,  even  that  fur- 
nished firom  the  Seine  and  canals,  is  excellent,  and  may 
be  drunk  with  impunity,  provided  it  is  properly  filtered. 


September  20,  1884.] 


THfe  MEDICAL  RECORD. 


335 


M.  Bouchardat,  who  seems  rather  inclined  to  be  persona), 
again  puts  himself  forward  as  an  example  of  the  innocu- 
ous influence  of  the  Paris  water,  which  he  has  been  drink- 
ing for  so  many  years,  and  he  holds  up  also  M.  Chevreul 
as  another  example,  this  eminent  chemist  being  on  the 
eve  of  entering  his  ninety-ninth  year. 

The  cholera  is  still  lurking  about  the  south  of  France, 
but  the  epidemic  is  localized  in  the  departments  in  the  lit- 
toral of  the  Mediterranean.  There  has  been  rather  an 
increase  lately  in  the  mortality  at  Toulon  and  Marseilles, 
which  has  been  attributed  to  the  return  of  the  fugitives 
and  to  the  continued  insanitary  condition  of  these  places. 


PERIOD    OF    GREATEST    RISK    FROM    CON- 
SUMPTION. 

To  THB  Editor  op  Thb  Medical  Rxcord. 

Sir:  The  communication  of  Dr.  Marsh  in  your  issue 
of  August  1 6th  has  come  to  my  notice  on  return  from 
vacation. 

The  facts  and  figures  were  not  supposed  to  be  new, 
nor  the  conclusion  previously  unknown,  but  they  cer* 
tainly  have  never  been  accepted  as  established. 

Over  and  over  again  the  subject  has  been .  presented 
in  various  journals,  and  your  own  issue  of  August  30, 
1884,  calls  attention  to  tlie  publication  of  an  article  by 
Dr.  Baker,  of  Michigan,  issued  in  1872. 

The  material  in  my  possession  on  the  subject  renders 
amusing  the  possibility  of  my  ignorance  of  the  views  of 
the  authors  to  whom  your  correspondent  alludes ;  but 
drawing  from  this  material,  and  using  only  such  as  con- 
siderable labor  warranted  me  in  believing  reliable,  I  was 
strack  with  the  aggregate  force  of  the  information,  and 
sought  to  call  this,  and  this  only,  to  the  attention  of  the 
profession 

The  work  alluded  to  by  Dr.  Marsh,  and  for  which  the 
compiler  is  entitled  to  great  credit,  is  not  a  private  or 
unknown  document,  but  an  open  book,  issued  by  the 
Mutual  Life  Insurance  Company  for  its  own  purposes, 
and  for  several  years  well  known  to  the  public,  as  well  as 
to  medical  men,  and  I  certainly  have  no  desire  to  gain 
credit  for  what  is  already  public  property. 

The  reliability  of  figures  published  by  Life  Insurance 
Companies  would  seem  to  render  superfluous  the  con- 
siderable labor  sarcastically  alluded  to  by  your  corre- 
spondent. Nevertheless,  sdl  the  material  drawn  upon, 
and  much  not  used,  was  carefully  gone  over,  as  Car  as  the 
original  facts  were  attainable,  and  the  experience  of  the 
Mutual  Benefit  subjected  to  a  like  investigation  ;  but  as 
I  did  not  suppose  it  necessalry  to  say  that  the  experience 
of  the  Mutual  Life  was  compiled  by  other  hands,  so  I 
did  not  suppose  I  was  claiming  credit  for  any  others 
that  I  might  choose  to  select  as  equally  reliable. 

Had  your  correspondent  taken  the  very  slight  trouble 
to  notify  me  by  letter,  or  otherwise,  of  failure  to  give 
credit  to  himself  or  the  company  he  represented,  it 
would  have  been  promptly  accorded. 

Dr.  Baker,  with  becoming  modesty,  claims  even  the 
diagram,  or  a  similar  one,  and  to  this  originality  he  is 
welcome,  if  only  the  views  presented,  old  to  a  few^  new 
(0  the  many^  receive  attention. 

Edgar  Holden,  Ph.D. 

NiwiUK,  N.  J. 

HIPPOCAMPUS    KS.    HYPOCAMPA. 

To  TfUt  Editor  op  Thb  Mboical  Rxcoro. 

Su :  Among  the  changes  from  the  nomenclature  now  in 
use,  suggested  by  Wilder,  is  the  adoption  of ''  hypocampa  " 
for  "  hippocampus."  His  chief  reasons  are  the  occurrence 
of  this  term  in  Vicq  d'Azyr's  work,  and  a  morphological 
one  to  be  refeired  to.  It  is  difficult  to  see  what  is  to  be 
gauned  by  this  adoption  of  what  may  be  the  product  of  a 
typographical  error  in  Vicq  d'Azyr's  work,  who,  quoting 
Aiantius  and  Varolius  as  the  discoverers  of  the  hippo- 
^^^pus,  gives  ''  hippocampus  '*  as  the  name  in  his  glos- 
sary of  anatomical  terms,  and  hypocampe,  with  the  Latin 


forms  hypocamfus  and  hypocampi  in  several  figure  refer- 
ences. The  transformation  of  a  hastily  written  *'  ip  "  to 
a  *'y  "  is  a  common  one  with  printers,  and  may  have 
been  indulged  in  by  the  old  copyists.  The  use  of  the 
term  by  the  discoverer  is,  we  think,  the  determining  factor 
here.  Although  Arantius  is  not  accessible  to  us,  yet 
there  is  a  very  full  citation  of  his  description  in  that  mag* 
nificent  work,  Burdach's  '*  Vom  Bau  und  Leben  des  Ge* 
hirns."  He  cites  Arantius  (page  45,  chapter  iii.,  of  the 
latter's  observations)  as  the  discoverer  of  the  hippocam- 
pus^ and  as  he  is  exceedingly  accurate  in  citation,  his 
work  being  the  most  complete  and  painstaking  bibli- 
ograpy  of  the  subject  of  cerebral  anatomy  up  to  the  year 
18 19  extant,  it  is  to  be  assumed  that  he  saw  the  original 
lines  when  he  says  "Arantius  discovered  it,  and  de- 
scribed it  as  a  white  prominence  resembling  a  hippocam" 
pus  or  a  vermis  bombycinus^^  which  having  its  head  in  the 
third  cavity,  extends  through  the  inferior  cornu,  circum- 
scribes the  crus,  and  ends  anteriorly  with  a  bent  round 
tail."  That  some  obscure  resemblance  of  the  head  to 
the  fish  known  as  the  sea-horse,  or  hippocampus,  was  be- 
fore Arantius  in  penning  this  description,  I  think  there 
can  be  little  doubt. 

Wilder  has  possibly  been  misled  by  the  accepted  use 
of  the  terms  pes  hippocampi  major  and  pes  hippocampi 
minor,  which  are  both  manifestly  improper.  On  this 
head  Burdach  is  again  very  explicit  and  satisfactory. 
He  says  that  of  the  term  hippocamp,  by  a  curious  niis« 
understanding,  the  authors — instancing  Mayer — made 
pes  hippocampi.  Inasmuch  as  the  sea-horse  has  no  foot, 
either  large  or  small,  Mayer  and  Reil  endeavored  to 
elude  the  quandary,  by  using  the  term  pes  hippopotami. 
The  question  is  disposed  of  by  the  adoption  of  *'  calcar  '* 
for  the  eminence  in  the  occipital  horn,  and  '*  digitati- 
ones "  for  the  series  of  eminences  in  the  temporal  horn 
of  the  ventricles,  so  that  hippocampus  may  be  retained 
for  the  gross  prominence  of  the  involuted  cerebral  wall, 
as  ''cornu  ammonis"  indicates  its  appearance  in  sec- 
tion. 

Burdach  has  a  dozen  references  in  his  foot-notes  to 
Vicq  d'Azyr's  figures,  which  indicate  a  detailed  and  at- 
tentive study  both  of  these  and  of  the  text  of  that  work. 
His  silence  on  the  subject  of  hypocampe — since  he  was 
at  one  and  the  same  time  an  excellent  classical  scholar, 
a  painstaking  reader,  and  acquainted,  as  is  evident,  with 
the  older  literature  beyond  even  Vicq  d'Azyr — seems  to 
indicate  that  he  regarded  it  as  a  printer's  or  clerical  error, 
and  relied  on  the  list  of  anatomical  terms  furnished  by 
Vicq  d'Azyr  as  the  proper  interpretation  of  the  latter's 
nomenclatural  views. 

It  is  singular  that  Burdach,  who  in  the  two  hundred 
and  seventieth  annotation  of  his  second  volume  cites  the 
entire  literature  regarding  the  hippocampus,  and  who  was 
so  thoroughly  acquainted  with  Vicq  d'Azyr's  work, 
should  fail  to  note  Varolius  as  sharing  in  the  discovery 
of  the  hippocamp,  which  Vicq  d*Azyr  maintains.  Aran- 
tius and  Varolius  were  contemporaries,  both  made  thetr 
discoveries  at  Bologna,  and  published  their  treatises  at 
nearly  the  same  time.  Of  the  two  the  great  Vatx)liu8 
was  undoubtedly  the  one  most  deserving  of  the  title 
Genius,  and  as  much  in  advance  of  his  day  as  Willis  was 
of  his,  but  it  must  not  be  forgotten  that  Arantitis  was  a 
close  observer,  and  devoted  special  attention  to  the  tem- 
poral comua,  which  he  erroneously  elevated  to  the  posi- 
tion of  independent  cavities,  capable,  as  the  primitive 
anatomy  of  that  time  permitted  him  to  say,  of  taking  up 
air  1  The  omission  of  Burdach* s — if  it  be  such — is  the 
more  remarkable,  as  in  his  historical  chapter,  when  he 
arrives  at  what  he  calls  the  "  sixth  period "  of  cerebral 
anatomy  (15  73-1641),  he  designates  it  the  period  of  Va- 
rolius, and  opens  its  consideration  with  these  lines :  '<  With 
deepest  veneration  I  mention  Varolius  (1573)  one  of  the 
greatest  names  which  the  history  of  our  science  reveals." 
The  close  of  the  paragraph  seems  to  indicate  that  there 

^Caterpillar  of  the  silk-^ 


336 


THE   MEDICAL  RECOTlD. 


[September  20,  1884, 


were  at  that  time  in  Bologna,  as  to-day  in  New  York, 
men  whose  work  was  done  on  the  same  plan  as  that 
shown  in  a  recent  much-criticized  "Anatomy  of  the 
Nervous  System."  But  nowhere  does  Burdach,  although 
he  gives  a  summary  of  Varolius'  contributions,  assign  to 
him  any  connection  with  the  earlier  descriptions  of  the 
hippocamp.  Aside  from  Arantius,  he  gives  the  names 
of  the  following  as  having  variously  described  and  inter- 
preted this  body :  Marchetti,  Molinetti,  Duvemoi,  Mo- 
rand,  Aubert,  Winslow,  Bergen,  Bonhomme,  Wrede,  Hal- 
ler,  Mayer,  and  Malacame.  The  connection  of  the 
hippocamp  and  the  fornix  was  known  to  Aran  tins,  who 
undoubtedly  had  a  clear  idea  of  the  gross  relations  of 
these  two  bodies.  As  Burdach  states,  all  knowledge  of 
the  hippocamp  was  lost  after  the  days  of  Arantius,  Mar- 
chetti,  and  Molinetti,  neither  Willis  nor  Vieussens  ap- 
pearing to  have  known  of  it  or  paid  any  attention  to  it. 
The  discovery  of  Arantius  was  not  resuscitated  till  the 
days  of  Morand,  being  buried  in  oblivion  for  ni^h  a  century. 

Let  the  observer  look  at  Plate  XX.  of  Vicq  d'Azyr,* 
which  represents  the  temporal  cornua  of  the  lateral  ven- 
tricles as  opened  from  below,  and  he  will  appreciate  how 
the  older  anatomists  interpreted  the  hippocampus.  One 
is  almost  inclined  to  suspect  that  the  artist — the  general 
correctness  of  whose  representations  is  remarkable — has 
been  biassed  by  the  name,  for  the  denticulations  of  the 
fasciola  (fascia)  dentata  and  the  sweep  of  the  bodv  of 
the  hippocamp  are  made  to  resemble  the  characteristic 
position  and  the  jointed  scales  of  the  sea-horse/  while 
the  digitations  are  represented  as  much  as  possible  like 
the  head  of  a  traditional  dolphin,  with  a  distinct  eye  and 
snout,  inverting  Arantius'  "  tail." 

Had  it  been  Vicq  d'Azyr's  intention  to  introduce  "hy- 
pocampe  "  into  nomenclature  it  would  be  certainly  re- 
markable that,  having  used  it  in  the  references  to  Plates 
VII.  and  VIII.  in  a  few  places,  he  should  resume  hippo- 
campe  and  hippocampus  in  the  last  or  fourth  part  of  the 
volume.  He  also  uses  hypocampi  as  a  genitive  form. 
This  strikes  me  as  signal  evidence  that  the  ''y"is  a 
printer's  error,  as  the  correct  form  (as  Wilder  has  it) 
would  be  hypocampae.  Vicq  d'Azyr's  last  reference  to 
these  bodies  reads  '*  hippocampe,"  and  on  one  page,  that 
relating  to  Plate  XX.,  this  form  occurs  just  ten  times, 
besides  once  on  the  following  page,  in  the  heading,  as 
well  as  in  the  full-page  title.  There  seems  to  be — taking 
the  inconsistency  of  ''  hypocampi "  grammatically,  the 
numerical  preponderance  of  hippocampe  and  hippocampus 
over  hypocampe^  and  the  way  hippocampus  is  spelled  in 
the  glossary — no  doubt  that  Vicq  d*  Azyr  recognized  only 
hippocampe  as  correct,  and  that  the  other  form,  as  I 
have  stated,  is  a  misprint. 

Of  course,  the  attributing  to  the  hippocamp  of  a  **foot " 
was,  as  Burdach  and  Reil  recognized,  improper.  The 
''pes  hippocampi,"  resembles  nothing  so  much  as  the 
foot  of  a  cat  with  retracted  claws,  and  I  have  a  faint 
recollection  of  reading  the  synonym  pes  leonis  applied 
to  it,  though  I  may  be  wrong.  Seeing  this  resemblance, 
and  finding  that  the  "pes  "  was  a  part  of  the  hippocamp, 
the  ox  and  the  ass  were  yoked  together — not  the  first 
time  in  the  history  of  medical  and  zoological  nomencla- 
ture— ^and  a  fish  became  endowed  with  a  cat's  paw. 

The  discoverer  of  the  hippocampus  can  have  had  only 
an  animal  resemblance  in  mind,  or  he  would  not  have 
used  as  a  second  simile  a  caterpillar.  The  ''  ribbing  "  of 
the  fasciola,  suggested  to  his  mind  the  jointed  structure 
of  the  fish  known  as  the  sea-horse  as  well  as  that  of  in- 
sectean  larva. 

Wilder  asks  the  question,'  whether  the  denticulations 
of  the  fasciola  are  found  in  other  animals  than  man,  and 
whether  they  are  recent  appearances  in  all  cases,  and 

^Tnit^  d'Anatomie  et  de  Physiologic,  tome  premier,  Paris,  1786.  It  may 
mterest  the  student  of  history  and  particularly  hun  who  delights  in  detecting  the 
sarcasm  of  events,  to  learn  that  this  magnificent  work  is  dedicated  "  to  Louis  XVI., 
to  whom  thirteen  Sutes  of  the  New  World  owe  their  liberty,  the  sea  its  indepen- 
dence, Europe  peace,  France  monuments  of  justice,"  ete.,  all  of  which  culmi- 
nated a  little  later  on  the  guillotine. 

'  Hippocampus  Hudsonius. 

*  In  ha  Cartwright  Lectures. 


have  been  accounted  for.  The  finest  denticulations  I 
have  seen  were  in  the  hippopotamus  and  the  common 
horse ;  they  seem  to  be  better  marked  in  children  than 
in  adults.  Meynert  offers  a  reason  for  their  existence, 
based  on  the  alternate  distribution  of  fibres.  That  they 
are  a  very  widely  spread  character  of  the  fasciola  is 
shown  by  the  following  list  of -animals  in  which  their 
presence  has  been  distinctly  noted  by  me  :  Man,  orang- 
outang, chimpanzee,  semnopithecus^  cercopithecus^  maca^ 
cusy  cynocephalus^  aUleSy  hippopotamus,  horse,  goat,  calf, 
sheep,  and  in  others  of  which  the  notes  are  difficult  of 
access  at  this  moment. 

Respectfully,  E.  C.  Spitzka,  M.D. 


|i.mxs  atxd  g^ws  g^cuxB. 


Official  List  of  Changes  in  the  StaO&HS  astd  Duties  of  Qficm 
tertdue  in  the  MeaiceU  Departnunt^  United  Stata  Army, 
from  September  7  to  September  13,  1884* 

Greenleaf,  Charles  R.,  Major  and  Surgeon.  To 
conduct  a  detachment  of  recruits  to  the  Department  of 
the  Columbia,  and  upon  completion  of  this  duty  rejoin 
his  station,  Columbus  Barracks,  Ohio.  S.  O.  210,  A.  CO., 
September  6,  1884. 

GoKGAS,  W.  C,  First  Lieutenant  and  Assistant  Sur- 
geon.    Assigned  to  duty  at  Fort  Randall,  D.  T.     S.  0. 

98,  Department  of  Dakota,  September  5,  1884. 
Egan,  p.  R.,  First  Lieutenant  and  Assistant  Surgeon. 

When  relieved  by  Assistant  Surgeon  Fisher,  to  report  at 
Fort  Lowell,  A.  T.,  for  duty  as  Post  Surgeon.  S.  0. 82, 
Department  of  Arizona,  September  2,  1884. 

Macauley,  C.  N.'  B.,  First  Lieutenant  and  Assistant 
Surgeon.  Assigned  to  duty  at  Fort  Sisseton,  D.  T.    S.  0. 

99,  Department  of  Dakota,  September  6,  1884. 
Fisher,  W.  W.  R.,  First  Lieutenant  and  Assistant 

Surgeon.  Assigned  to  duty  at  Fort  Apache,  A.  T.,  re- 
lieving Assistant  Surgeon  Egan.  S.  O.  82,  C.  S.,  Depart- 
ment of  Arizona. 

EwiNG,  Charles  B.,  First  Lieutenant  and  Assistant 
Surgeon.  Assigned  to  duty  as  Post  Surgeon  at  Fort 
Stanton,  N.  M.  S.  O.  177,  Department  of  the  Missouri, 
September  6,  1884. 

McCaw,  W.  D.,  First  Lieutenant  and  Assistant  Sur- 
geon (recently  appointed).  To  report  in  person  to  the 
Commanding  General  Department  of  the  Missouri,  for 
assignment  to  duty.  S.  O.  209,  A.  G.  O.,  September  5, 
1884.  

Official  List  of  Changes  in  the  Medical  Corps  of  the  U,  5. 
Navy^  during  the  week  ending  September  13,  1884. 

Hevl,  T.  C,  Surgeon.  From  the  Adams  to  the  Re- 
ceiving Ship  Independence,  Mare  Island,  CaL  Septem- 
ber 8,  1884. 


pmcdical  Stems. 


CoMTACHOus  Diseases — ^Weekly  Statememt.— Re- 
port of  cases  and  deaths  from  contagioas  diseases  re- 
ported to  the  Sanitary  Bureaa»  Health  Department,  for 
the  week  ending  September  13,  1884 : 


WeekEndiBf 


September  6,  1884 
September  13,  1884 

D^tUks, 
September  6,  1884. 
September  13,  1884 


900 

II    0    0 


The   Medical   Re 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  13 


New  York,  September  27,  1884 


Whole  No.  72s 


©rieitml  %xXxtXz&. 


A  SUCCESSFUL  CASE   OF  ARREST  OF  TUBAL 
PREGNANCY  BY  GALVANISM. 


By  PAUL  F.  MUNDfi,  M.D., 


mnr  yosk. 


Instances  of  extrauterine  pregnancy  observed  at  so  early 
a  period  as  to  admit  not  only  of  a  certain  diagnosis,  but  of 
their  successful  treatment,  are  not  so  common,  but  that, 
as  yet,  each  additional  case  presents  features  of  interest 
sufficient  to  warrant  placing  it  on  record.  Of  late,  two 
cases  have  been  reported  by  Veith,  of  Berlin,  of  success- 
ful removal  by  laparotomy  of  the  whole  sac  in  tubal 
pregnancy,  in  the  first  case  the  diagnosis  being  obscure, 
in  the  second  case  clearly  made  before  the  operation 
was  decided  upon.  It  is  possible  that  at  some  future 
time  the  details  of  laparotomy  may  be  so  simplified  that 
a  fatal  termination  is  a  rare  exception  ;  but  at  the  present 
day,  in  spite  of  Tail's  wonderful  results,  the  fact  remains 
andisputed  that  every  patient  whose  abdominal  cavity  is 
opened  incurs  the  nsk  of  losing  her  life.  So  long  as 
that  is  the  case,  the  majority  of  operators  will  hesitate 
before  performing  a  dangerous  operation,  when  the  same 
result  can  be  obtained,  at  least  so  far  as  a  continuance 
of  the  gestation  is  concerned,  by  an  entirely  harmless 
and  simple  process.  Whether  now  this  process,  the  pas- 
sage of  an  electric  current  through  the  gestation-sac,  is 
so  entirely  harmless,  and  whether  it  can  be  relied  upon 
always  to  arrest  the  growth  of  the  ovum  and  its  en- 
velopes, and  finally  whether  the  ovum  so  arrested  is  a 
safe  thing  to  have  in  the  abdominal  cavity  ad  indejinitum^ 
these  are  points  which  only  additional  observations  will 
decide.  As  a  contribution  to  the  settlement  of  these 
questions  the  following  case  is  reported  : 

Mrs.  P.  A ^  thirty-eight  years  of  age,  mother  of  one 

child  eight  years  of  age,  one  miscarriage  six  years  pre- 
viously, consulted  me  February  6,  1884,  in  order  to 
ascertain  whether  she  was  pregnant.  She  stated  that 
she  had  last  menstruated  during  the  last  week  of 
November,  1883,  that  she  had  had  connection  imme- 
diately after  the  cessation  of  the  flow,  December  ist, 
and  not  since,  as  she  soon  began  to  feel  nauseated,  and 
being  afraid  of  becoming  pregnant  had  avoided  inter- 
course. Her  next  menstrual  period,  due  about  Christ- 
mas, passed  without  a  show,  but  early  in  January  there 
was  some  bloody  discharge,  although  much  less  than 
usual.  She  also  began  to  feel  colicky  pains  in  the  lower 
part  of  the  abdomen,  which,  together  with  the  nausea, 
persisted  until  I  saw  her,  and  were  gradually  growing 
worse.  She  said  that  her  appetite  was  good,  but  that  she 
invariably  vomited  soon  after  eating.  Morning-sickness 
was  not  specially  marked.  When  she  came  to  me  she 
had  just  had  a  second  scanty  show  of  blood.  For  several 
days  the  abdominal  pain  had  produced  some  faintness, 
and  her  weakness  had  increased  considerably.  She  was 
a  tall,  graceful  woman,  rather  thin  and  pale,  and  bore 
traces  of  suffering  in  her  face.  A  vaginal  examination 
showed  the  uterus  pushed  somewhat  to  the  left  side,  but 
slightly,  if  any,  enlarged,  and  in  the  right  half  of  the 
pelvic  cavity  an  oblong,  irregular,  deeply  fluctuating 
mass  of  the  size  of  a  goose's  egg,  which  could  be  slightly 
moved  about,  causing  the  uterus  to  move  with  it.  Bi- 
manual palpation  of  this  mass  caused  intense  pain,  and 
brought  on  faintness  and  the  colicky,  cramp-like  pains 


of  which  the  patient  had  complained.  Large  vessels 
could  be  felt  pulsating  through  the  right  vaginal  pouch. 
Feeling  confident  that  the  uterus  was  empty,  for  it  cer- 
tainly was  not  enlarged  to  the  size  of  a  two  months' 
pregnancy,  I  introduced  the  sound,  and  it  entered 
toward  the  left  to  a  depth  of  three  inches.  My  already 
formed  diagnosis  of  tubal  pregnancy  was  confirmed  by 
the  appearance  of  the  areolae,  and  the  oozing  of  colos- 
trum from  the  nipples  on  pressure,  certainly  unusual  ex- 
cept  as  a  sign  of  pregnancy  in  a  woman  who  had  not 
been  pregnant  for  six  years.  The  breasts  were  not  en- 
larged, however,  although  the  lady  said  that  they  felt 
rather  fuller  than  usual. 

I  explained  to  the  patient  and  her  husband  what  I 
thought  to  be  the  trouble,  and  the  danger  of  allowing  the 
pregnancy  to  proceed,  and  the  hope  I  had  of  checking 
its  growth  by  the  electric  current.  But  in  order  to  share 
the  responsibility,  and  as  a  guarantee  of  the  corrtctness 
of  the  diagnosis,  I  proposed  a  consultation  with  Dr. 
Thomas  Addis  Emmet,  which  was  readily  agreed  to. 
He  saw  the  patient  at  his  office  the  next  day  in  my  ])res- 
ence,  and  without  giving  him  my  diagnosis,  which  I  told 
him  I  had  formed  the  day  before,  he  at  once  pronounced 
it  to  be  a  pregnancy  in  the  right  tube,  and  advised  the 
galvanic  current. 

The  patient  had  already  felt  considerably  prostrated 
before  going  to  Dr.  Emmet,  where  she  was  obliged  to  ride 
in  a  carriage,  although  perfectly  able  to  come  to  me  the 
day  before  in  the  horse-cars,  and  after  his  examination 
she  had  so  much  pain  that  I  prescribed  a  morphine  sup- 
pository, to  be  taken  as  soon  as  she  reached  home.  Fear- 
ing that  delay  might  result  in  a  rupture  of  the  sac,  I  ar- 
ranged to  go  to  her  residence  that  afternoon  with  my^ 
battery  and  pass  a  current  through  the  mass.  Accord- 
ingly  I  went  there  at  4  p.m.,  and  found  the  lady  so  much 
prostrated,  that  her  husband  met  me  at  the  door  with 
the  words,  "  I  fear,  doctor,  you  cannot  do  anything  to- 
day." But  the  danger  of  rupture  was  so  vivid  before  my 
mind,  that  I  preferred  to  run  the  risk  of  producing  that 
rupture  by  the  electricity,  rather  than  what  seemed  to 
me  the  greater  risk  of  allowing  the  sac  to  grow  even 
twenty-four  hours  longer.  Placing  a  leather-covered 
button  electrode  in  the  rectum,  and  the  other  pole  by  a 
flat  sponge  on  the  abdomen  over  the  mass,  I  passed  the 
current  of  my  newly  filled  galvanic  battery  through  the 
sac,  gradually  increasing  its  strength  to  twenty-four  cells, 
and  rapidly  breaking  the  current  a  dozen  times  or  more. 
The  sitting  lasted  about  ten  minutes,  and  the  shocks 
were  quite  painful.  I  did.  not  think  this  current  too 
strong,  for  I  remembered  that  in  one  of  the  successful  cases 
reported,  McBurney's  thirty-six  cells  had  been  used.  I 
left  the  patient  fairly  comfortable,  no  more  prostrated 
than  before  the  application. 

Early  the  next  morning  I  was  called,  and  when  I  ar- 
rived I  learned  that  the  lady,  whose  nausea  and  retching 
had  continued  all  night,  had  sat  up  in  bed  toward  morn- 
ing to  vomit,  had  been  seized  by  a  violent  pain  in  the 
abdomen,  and  had  fallen  back  in  a  faint.  I  found  her 
perfectly  conscious,  but  white  as  a  sheet,  with  pinched, 
clammy  features,  absolutely  pulseless  at  either  wrist,  skin 
cool,  extremities  cold.  I  naturally  thought  that  the  sac 
had  ruptured  ;  the  history  and  present  condition  clearly 
pointed  to  that  conclusion.  One  thing  only  led  me  to 
doubt  a  rupture,  and  that  was  the  strength  with  which  the 
patient  could  turn  about  in  bed  and  answer  questions.  It 
was  evidently  a  state  of  collapse,  but  it  did  not  seem  to 


338 


THE  MEDICAL  RECORD. 

t 


[September  27,  1884* 


nie  exactly  like  prostration  from  hemorrhage.  I  could 
not  but  hope  that  it  might  be  merely  shock  from  the  re- 
peated examinations  and  the  galvanic  current  through  so 
sensitive  an  organ  as  an  overdistended  tube.  I  made  a 
gentle  va^nal  examination  and  found  the  outline  of  the 
mass  as  distinct  as  the  day  before.  In  any  case,  the  only 
^active  measure,  laparotomy,  could  not  be  carried  out  on 
a.  patient  in  so  profound  a  state  of  collapse  as  to  be 
pulseless  at  the  wrists ;  she  must  simply  have  died  on 
the  table.  Hence,  if  there  was  a  rupture,  all  I  could  do 
was  to  stimulate  her  until  she  rallied  sufficiently  to  justify 
laparotomy;  and  if  there  was  no  rupture,  then  that 
operation  was  not  indicated.  I  therefore  ordered  hypo- 
dermics of  brandy,  each  containing  five  minims  of  arom. 
spir.  ammonia,  one  to  be  given  every  fifteen  minutes  in 
diflferent  parts  of  the  body  <the  patient's  stomach  would 
retain  absolutely  nothing),  sent  for  a  nurse,  and  went 
home  for  my  laparotomy  instruments,  in  case  at  any  mo- 
ment they  should  be  required.  The  physician  who  was 
hurriedly  called  in,  and  whom  I  found  at  the  bedside  when 
I  arrived.  Dr.  Black,  of  the  United  States  Army,  on 
leave  of  absence  and  temporarily  residing  in  the  neigh- 
borhood, kindly  stayed  with  the  patient,  and  was  relieved 
later  by  my  assistant.  Dr.  E.  H.  Grandin.  On  my  re- 
turn several  hours  later,  I  found  the  condition  unchanged. 
The  hypodermics  were  continued  during  the  day,  some 
fifty  in  all  being  given. 

During  the  afternoon,  while  on  my  way  to  Mount 
Sinai  Hospital,  where  I  was  to  operate,  1  met  Dr. 
Charles  K.  Briddon  in  the  car,  and  remembering  his 
recently  reported  case  of  laparotomy  after  rupture  of  a 
tubal  gestation-sac,  related  my  case  to  him,  and  the  doubt 
I  was  m  as  to  whether  rupture  had  occurred,  and  whether 
I  should  operate  or  await  developments.  He  strongly 
advised  me  to  operate  at  once  in  spite  of  the  collapse, 
saying  that  his  patient  also  was  pulseless,  but  that  after 
the  operation  her  pulse  rose.  I  decided  to  wait,  however, 
still  feeling  that,  after  all,  it  might  be  nothing  but  shock. 

The  next  morning  there  was  a  faint  trace  of  pulsation 
at  the  wrist ;  gradually  it  increased,  and  we  began  to 
hope ;  the  retching  diminished  and  the  patient  could  re- 
tain cracked  ice.  Her  abdomen  was  very  sore,  and  she 
complained  a  great  deal  of  colicky  pains  on  the  right  side. 
To  make  a  long  story  short,  she  gradually  rallied,  began 
to  retain  nourishment,  and  in  a  week  was  able  to  sit  up 
in  bed,  and  in  two  weeks  lie  on  a  lounge.  The  sac  had 
become  somewhat  harder,  fluctuation  was  less  distinct, 
pulsation  had  disappeared,  but  the  mass  was  not  per- 
ceptibly smaller.  The  breasts  had  become  flabby,  but 
they  still  secreted  colostrum.  Although  there  could  not 
be  any  reasonable  doubt  of  the  death  of  the  foetus  after 
such  a  series  of  galvanic  shocks,  still,  to  make  sure,  1 
thought  it  best  to  pass  the  faradic  current  through  the 
sac  a  number  of  times,  and  beginning  on  the  sixteenth 
day  after  the  galvanic  sitting,  I  made  six  faradic  applica- 
tions  to  the  sac,  one  pole  in  the  vagina,  the  other  over 
the  mass  on  the  abdomen,  using  the  full  strength  of  a 
Kidder  tip-battery  and  frequently  breaking  the  current. 
One  sitting  per  day  was  given,  lasting  about  fifteen 
minutes.  This  treatment  caused  no  pain  or  shock  what- 
ever. From  this  time  on  the  patient  improved  rapidly, 
regained  her  flesh  and  color,  and  by  the  end  of  the  fourth 
week  was  able  to  go  out.  The  colostrum  gradually  dis- 
appeared from  the  breasts,  but  the  sac  diminished  very 
slowly,  so  that  when  I  last  saw  her  at  my  office  on  May 
19th,  three  months  and  a  half  after  the  galvanic  shock,  it 
was  certainly  still  two-thirds  as  large  as  at  first,  although 
perfectly  solid.  All  pain  in  it  had  ceased  before  she  was 
allowed  to  go  out.  Menstruation  reappeared  on  April 
1 2  th,  and  again  on  May  7th,  lasting  seven  days.  The 
uterus  was  measured  and  found  to  be  two  and  three- 
fourths  inches  deep.  The  lady  left  for  Europe  on  May 
2 1  St  in  perfect  health,  and  without  a  complaint  of  any 
kind,  and  is  still  abroad. 

The  special  points  of  interest  in  this  case  are :  first, 
the  occurrence  and  recognition  of  the  nature  of  the  col- 


lapse after  the  galvanic  sitting  ;  and  second,  the  kind  of 
current  which  should  be  used,  the  galvanic  or  the  faradic 
I.  As  regards  the  collapse.  I  have  no  doubt  that  it 
was  due  to  the  violent  galvanic  shocks  passed  through  a 
highly  sensitive  organ,  at  that  time  even  more  closely 
connected  than  usual  with  the  sympathetic  system,  and 
that  the  previous  examinations  had  sdready  paved  the  way 
for  such  an  occurrence. 

The  recognition  of  the  cause  of  the  collapse  was  not 
easy,  and  I  confess  that  I  expected  all  during  that  7th 
of  February  to  be  called  upon  at  any  moment  to  do 
laparotomy  as  a  last  resort.  But  I  wish  again  to  call  at- 
tention to  the  one  sjrraptom  which  led  me  to  defer  operat- 
ing, and  which,  givmg  it  its  correct  interpretation,  as  1 
chanced  to  do,  saved  the  patient's  life,  namely,  her 
singular  physical  strength,  while  pulseless  at  either  wrist 
and  evidently  collapsed  in  the  highest  degree.  Had  I 
not  considered  this  persistence  of  voluntary  muscular 
power  incompatible  with  the  loss  of  so  great  an  amount 
of  blood  (intra-abdominal,  of  course)  as  would  produce 
so  severe  a  collapse,  I  should  probably  have  done  what 
was  the  only  other  thing  to  do  but  wait,  that  is  laparotomy, 
which  I  do  not  think  the  patient  would  have  survived. 

2.  My  experience  with  the  |;alvanic  current  in  this  case 
leads  me  to  prefer  the  faradic,  which  has  been  success- 
fully used  by  Landis,  Allen,  Garrigues,  and  others,  with- 
out any  of  the  shock  or  pain  experienced  in  my  case.  1 
do  not  attribute  the  shock  entirely  to  the  character  or 
strength  of  the  current,  for  there  was  undoubtedly  some 
present  before  it  was  used,  and  I  am  disposed  to  believe 
that  rupture  was  impending  or  had  already  begun ;  but  I 
doubt  2r  the  shock  would  have  become  so  severe  if  I  had 
used  the  faradic  current.  But  the  faradic  will  need  to 
be  repeated  frequently  and  at  short  intervals  to  insure 
success. 

Whether  the  encysted  ovum  ever  gives  rise  to  subse- 
quent trouble  by  suppuration  or  septic  infection  I  do  not 
know.  As  no  such  result  has  been  mentioned  in  the  re- 
ported  cases,  I  suppose  it  is  fair  to  assume  that  its  growth 
once  arrested  it  simply  shrivels,  mummifies,  and  is  no 
longer  recognizable  except  as  a  small  hard  lump,  causing 
no  inconvenience  whatever. 

Although  I  have  heard  incidentally  of  one  or  two  other 
unpublished  cases  of  extra-uterine  pregnancy  checked  by 
electricity,  I  believe  this  is  the  twelfth  case  on  record, 
the  eleven  others  having  been  reported  by  Garrigues  in 
vol.  vii.  of  the  American  G3mecological  Society's  Trans- 
actions. 

ao  WcsT  FoBTY-nrra  Stkbbt. 


The  newspapers  state  that  two  persons,  one  of  whom 
was  a  physician,  have  surrendered  themselves  to  the  au- 
thorities of  Norristown,  Pa.,  and  have  admitted  the  steal- 
ing of  the  body  of  John  May,  a  murderer  and  suicide,  from 
the  cemetery  at  that  place.  The  purpose  for  which  the 
body  was  taken  is  not  mentioned,  but  it  was  doubtless  for 
dissection.  An  act  of  this  sort  is  certainly  criminal,  but 
it  is  interesting  to  note  the  trouble  the  old  law-writers 
have  had  in  detemiining  exactly  what  kind  of  a  crime  it 
was.  They  early  came  to  the  conclusion  that  it  was  not 
theft,  because  a  dead  body  could  not  be  property,  and  no 
one  could  be  said  to  have  ownership  in  a  corpse.  In 
one  case,  however,  it  was  held  to  be  robbery,  because 
the  grave  clothes  were  taken  as  well  as  the  corpse.  In 
more  recent  times,  the  act  has  been  regarded  as  one 
against  the  public  instead  of  an  individual,  and  heavy 
penalties  have  been  prescribed  against  those  who  wan- 
tonly open  a  grave.  At  the  same  time  most  States  and 
communities  have  laws  by  which  the  bodies  of  unknown 
and  friendless  persons  are  given  to  hospitals  and  medical 
schools  for  dissecting  purposes.  Such  laws  will  not,  how- 
ever, permit  the  removal  of  the  unknown  dead  from  ceme- 
teries where  they  have  been  interred  in  the  usual  way. 
Removal  secretly  of  the  bodies  of  such  persons  is  as  much 
an  offence  as  that  of  persons  who  are  well  known  and 
have  died  surrounded  by  their  friends. 


September  27,  i884,] 


THE  MEDICAL  RECORD. 


339 


TYPHUS  FEVER,  AS  IT  OCCURRED  IN  AN 
EPIDEMIC  AT  THE  PHILADELPHIA  HOS- 
PITAL, WITH  A  CONDENSED  REPORT  OF 
NINETEEN  CASES. 

By  LLOYD  NORRIS  HORWITZ,   M.D., 

LATB  BBSIDBMT  PHYSICIAN  TO  THB  PHILAIMILPHIA  HOSPITAL, 
PHUJLDBLPHIA,  PA. 

Although  this  report  embraces  but  the  record  of  nine- 
teen cases,  yet  the  writer's  conclusions  and  remarks  are 
founded  on  the  close  observation  and  postmortem  ex- 
ainination  of  over  forty  cases  which  occurred  in  the  wards 
of  his  colleagues  Drs.  Elder  and  Gotwald. 

This  epidemic  of  typhus  fever  began  about  March  i, 
18S3,  and  lasted  with  more  or  less  severity  until  June  of 
the  same  ^ear,  and  was  then  only  checked  by  the  strict 
prophylaxis  employed  by  the  physicians  at  the  hospital, 
assisted  by  the  hearty  co-operation  of  the  Board  of  Health, 
as  the  contagious,  infectious,  and  epidemic  character  of 
the  malady,  in  the  writer's  opinion,  was  clearly  proven  by 
the  cases  which  fell  under  his  direct  observation. 

Case  L — F.  W ,  white,  aged  thirty-four,  admitted 

to  the  hospital  March  2,  1883,  was  the  second  case  of 
typhus  fever  of  the  epidemic.  Precisely  like  four-fifths 
of  all  the  cases  admitted,  he  came  from  a  locality  in  this 
city  noted  for  its  filth,  its  unhealthy  and  unhygienic  sur- 
roundings, and  for  the  squalor  and  poverty  of  its  inhab- 
itants, namely  Alaska  and  St.  Mary's  Streets  and  the 
numerous  courts  and  alleys  immediately  adjacent 

Although  no  satisfactory  history  of  this  case  could  be 
obtained,  owing  to  the  patient's  semi-delirious  condition, 
still,  judging  from  his  symptoms,  he  must  have  been 
suffering  between  five  and  six  days  before  he  was  brought 
to  the  institution. 

The  patient  was  decidedly  emaciated;  his  tongue  was 
of  a  brown  dusky  hue,  but  red  at  its  tip ;  the  teeth  were 
covered  with  sordes,  and  the  breath  was  peculiarly  offen- 
sive. The  chest  and  lateral  aspect  of  the  body  as  well  as 
the  lower  portions  of  the  thighs  were  quite  thickly  cov- 
ered with  the  characteristic  eruption  of  typhus.  The 
urine  was  scanty  and  high  colored,  and  voided  with  much 
difficulty;  the  bowels  were  loose,  and  of  a  fetid  character, 
a  condition  in  the  writer's  experience  almost  as  common 
as  that  of  constipation.  The  temperature,  as  in  all  cases 
of  this  epidemic,  was  exceedingly  high,  it  being  at  the 
time  of  his  admission  105^^.  The  delirium  was  of  a  low, 
muttering  type,  and  contmued  so  until  the  beginning  of 
the  third  week,  and  indeed  it  may  here  be  remarked  that 
this  is  the  characteristic  delirium  •f  the  disease,  the  busy, 
violent  delirium  being  rarely  seen. 

The  writer  has  left  to  the  last  what,  in  his  opinion,  was 
one  of  the  most,  if  not  the  most  valuable  diagnostic 
symptom  of  the  disease,  namely,  muscular  and  osseous 
hypersesthesia  and  tenderness  on  pressure;  fer  no  matter 
in  what  condition  of  comatose  insensibility  was  the  pa* 
tient,  cries  of  pain  could  readily  be  elicited  by  even  slight 
pressure  over  the  tibia,  ulna,  humerus,  or  any  of  the  sub- 
cutaneous bones. 

The  peculiar  typhus  odor  from  the  skin  and  breath, 
referred  to  by  some  authors  as  so  characteristic  of  the 
disease,  is,  in  the  writer's  opinion,  of  but  little  value,  it 
often  being  entirely  absent,  as  was  the  case  with  this  pa- 
tient, and  when  present  was  in  no  way  distinguishable 
from  the  ordinary  smell  of  the  sick  ward,  and  the  writer 
may  also  add  in  this  connection  that  the  characteristic 
emption  of  the  disease  lends  but  little  diagnostic  aid  to 
the  practitioner,  both  on  account  of  its  frequent  absence, 
and  from  the  protracted  delay  in  making  its  appearance, 
and  as  proof  of  this  would  cite  the  nineteen  cases  of  his 
own,  in  which  but  ten  showed  any  eruption  whatever, 
and  in  two  of  these  the  eruption  did  not  make  its  appear- 
ance until  the  eighth  day  of  the  disease.  In  the  cases 
treated  by  my  colleagues,  above  referred  to,  the  eruption 
was  as  frequently  absent  or  protracted  in  its  appearance 
as  in  those  here  recorded. 

The  patient  remained  in  the  condition  described  until 


the  fifteenth  day  of  the  disease,  or  nine  days  after  his  ad« 
mission,  when  convalescence  commenced,  the  fever  and 
delirium  lessening,  diarrhoea  becoming  checked,  the  tongue 
cleaning  up,  and  strength  returning. 

It  may  be  here  remarked  that  the  overwheUnmg  mus- 
cular prostration  attending  the  cases  constitutes  one  of 
the  most  important  factors  of  the  disease,  and  is  even 
greater  than  that  which  attends  typhoid,  although  con- 
valescence takes  place  with  much  greater  rapidit}'  in 
typhus. 

At  the  beginning  of  the  fourth  week  the  man  was  able 
to  move  about  the  ward,  still  quite  weak.  A  few  days 
later  he  was  sent  to  the  convalescent  ward,  cured. 

Case  IL — J.  J ,  colored,  aged  sixty,  admitted  to 

the  hospital  March  7,  1883.  This  case  is  of  interest 
principally  on  account  of  its  rapidily  fatal  termination ; 
the  patient  having  died  thirty-six  hours  after  his  admission. 

The  history  of  this  case,  like  the  former,  was  very  un- 
satisfactory;  the  ambulance  doctor  being  unable  to  learn 
anything  from  the  sick  man's  drunken  and  bestial  com- 
panions. (It  may  be  remarked,  en  passant^  that  there 
were  no  less  than  twenty-eight  human  beings  living  in  a 
three-story  wooden  boarding-house  in  Alaska  Street,  from 
whence  he  was  brought).  However,  in  the  opinion  of  Dr. 
Bruen  and  the  writer,  it  was  one  of  those  fulminating  cases 
of  typhus  fever,  which  afterward  proved  by  no  means  of 
rare  occurrence  during  this  epidemic. 

The  man  was  in  a  completely  comatose  condition,  and 
could  only  be  aroused  for  a  moment  by  pressure  on  the 
extremities ;  the  tongue  and  teeth  were  in  the  usual  con- 
dition found  in  these  cases;  the  pulse  hard  and  very 
rapid,  showing  135  beats  per  minute  ;  the  temperature 
the  highest  of  any  case  that  came  under  my  observation, 
the  thermometer  io6f°;  and  finally,  on  examination  of 
the  bladder,  it  was  found  to  be  greatly  distended  with 
urine,  which  necessitated  the  use  of  the  catheter;  the 
operation  having  to  be  repeated  when  necessary  up  to 
the  time  of  the  patient's  death.  This  retention  of  urine 
was  found  to  be  generally  diagnostic  of  a  very  severe 
case,  it  having  occurred  in  every  fatal  instance. 

On  post-mortem  examination  the  viscera  were  found  to 
be  congested,  but  otherwise  in  a  normal  condition ;  this 
condition  was  particularly  noticeable  with  the  kidneys. 
The  intestines  were  carefully  examined,  and  no  point  of 
ulceration  could  anywhere  be  detected,  but  the  peculiar 
and  characteristic  "shaven  beard"  appearance  of  the 
mucous  membrane  was  noticed  in  spots  throughout  the 
whole  length  of  the  ilium.  The  precise  nature  and  micro- 
scopical anatomy  of  this  morbid  condition  has  not  to  my 
knowledge  been  definitely  described  by  pathologists,  but 
the  practical  fact  remains  that  it  was  noticed  in  every 
instance  in  which  a  post-mortem  examination  was  held. 

Case  HI. — J.  M ,  white,  aged  fifty-five,  admitted 

to  the  typhus  ward  March  24,  1883.  This  patient  was 
recently  convalescent  from  a  severe  attack  of  facial  ery- 
sipelas in  one  of  the  wards  of  the  hospital  when  stricken 
with  typhus  fever. 

His  condition  from  the  onset  was  grave,  the  fever  be- 
ing ushered  in  with  a  series  of  severe  chills,  and  intense 
nausea ;  the  latter  symptom  continuing  for  the  first  thirty- 
six  hours  of  the  disease.  All  the  symptoms  of  typhus 
were  well  developed  in  this  case ;  the  eruption  appearing 
quite  copiously  on  the  fifth  day. 

Nothing  beyond  the  persistent  nausea  was  noticed 
which  would  invest  this  case  with  any  particular  interest. 
Death  ensued  on  the  eighth  day.  The  autopsy  revealed 
precisely  the  same  pathological  conditions  as  seen  in 
Case  IL 

Cases  IV.  and  V.— John  J ,  thirty-eight  years  of 

age,  and  Wni.  J ,  thirty  years  of  age,  both  white. 

They  were  admitted  to  the  hospital  on  the  same  day,  and 
were  brought  from  the  same  house  on  Alaska  Street. 

They  both  gave  as  a  history  of  their  cases  a  feeling  of 
great  lassitude,  weariness,  and  a  condition  of  general 
malaise  for  several  days  prior  to  the  attack,  and  the  man 
J.  J had  a  severe  chill  while  being  conveyed  to  the 


340 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


hospital  in  the  ambulance.  The  eruption  did  not  appear 
in  the  first  case  until  the  seventh  day,  and  was  then  so 
slight  as  to  be  recognized  with  much  difficulty,  while  in 
the  second  patient  there  was  no  perceptible  eruption 
whatever. 

It  is  a  curious  fact,  but  one  well  borne  out  by  the 
writer*s  experience  in  this  epidemic,  that  in  these  cases 
in  which  the  eruption  was  slight  or  altogether  absent  the 
temperature  and  all  other  symptoms  were  increased  in 
severity.  This  fact  was  well  illustrated  in  these  two  cases, 
in  which  all  symptoms  were  of  the  gravest  character.  Con- 
stipation was  marked  in  the  first  case,  but  the  bowels 
were  rather  loose  than  otherwise  in  the  second. 

The  second  case  died  on  the  ninth  day  in  a  state  of 
complete  coma;  the  first,  however,  recovered  after  a 
protracted  illness  and  a  tedious  and  slow  convalescence. 

The  autopsy  held  on  the  second  case  revealed  pre- 
cisely the  same  morbid  conditions  as  in  Cases  II.  and 
III. 

Case  VI. — ^John  L ,  sixty-five  years  of  aj;e,  white, 

admitted  to  the  hospital  March  30,  1883,  This  patient 
was  also  brought  from  the  same  infected  locality  as  the 
preceding  ones.  There  was  at  the  time  of  his  admission 
a  slight  typhus  eruption  scattered  over  the  trunk,  which 
increased  greatly  in  the  next  twenty  fom:  hours,  and 
turned  to  a  dark  black  color  a  few  hours  before  his  death. 
The  thermometer  showed  a  temperature  of  104^°,  the 
significant  brown  tongue  and  an  unusual  degree  of  hyper- 
aesthesia  of  the  muscles  and  bones  were  present,  with  ex- 
treme prostration  and  low  delirium.  He  lingered  in  this 
condition  for  two  days,  when  he  died. 

On  post-mortem  examination  the  viscera  were  found 
to  be  more  than  usually  congested,  especially  the  lungs. 
The  same  pathological  changes  were  found  in  the  intes- 
tines as  in  the  preceding  cases. 

Case   VII. — Thomas   R ,  twenty-eight    years  of 

age,  white,  admitted  April  2d.  The  diagnosis  of  this 
case  was  for  a  time  involved  in  some  doubt,  as  in  its 
early  course  it  closely  resembled  typhoid  fever,  but  the 
appearance  of  the  eruption  on  the  fifth  day,  the  peculiar 
brown  tongue  before  described,  and  the  muscular  hyper- 
aesthesia,  made  the  diagnosis  at  that  time  positive.  The 
attack  was  comparatively  light,  the  temperature  never 
reaching  over  102^°;  the  muscular  hy perse sthesia  being 
not  so  well  marked  as  in  graver  cases,  and  the  patient 
being  able  to  be  aroused  from  his  stupor  from  time  to 
time. 

Convalescence  set  in  toward  the  end  of  the  third 
week,  and  complete  recovery  quickly  ensued.  The  re- 
turn to  health  and  strength,  as  in  most  cases  of  this  dis- 
ease, was  quite  rapid. 

Casks  VIII.  and  IX. — Charles  A ,  thirty-two  years 

of  age,  and  Joseph  P ,  thirty-six  years  of  age,  both 

colored,  the  former  admitted  March  30th,  the  latter 
March  31st.  They  were  brought  from  the  same  shanty, 
situated  in  a  small  alley  running  off  Alaska  Street,  and 
according  to  their  own  statements  they  were  both  taken 
sick  about  the  same  time.  The  first  case  was  of  that 
fulminating  character  described  in  a  former  patient,  and 
he  died  in  a  state  of  complete  coma  on  the  fifth  day  after 
his  admission.  The  retention  of  urine  and  his  profound 
comatose  insensibility  almost  from  the  onset  of  the  at- 
tack formed  the  two  most  prominent  symptoms  of  the 
case ;  constipation,  muscular,  and  osseous  hypersesthesia 
were  present  in  a  marked  degree.  The  autopsy  revealed 
the  usual  congestion  of  the  viscera  and  the  '*  shaven- 
beard"  appearance  of  the  raucous  membrane  of  the 
ilium.  The  brain  was  found  in  a  normal  condition,  ex- 
cept a  slight  increase  in  the  '*  puncta  vasculosa." 

The  second  case  was  of  a  light  character,  and  was 
analogous  to  Case  VII.  The  individual  was  completely 
convalescent  by  the  fourth  week,  and  his  subsequent  re- 
covery was  rapid. 

Case  X. — ^Joseph  D ,  thirty-six  years  of  age,  white, 

admitted  April  2,  1883.     The  patient  gave  a  history  of 
prostration  and  fever  for  three  days  prior  to  his  entrance 


into  the  hospital.  When  first  seen  no  eruption  could  be 
detected  on  any  portion  of  the  body,  but  on  the  fifth  day 
of  the  disease,  or  two  days  after  his  admission,  a  few 
spots  were  noticed  on  the  lower  extremities;  all  the 
other  symptoms  of  typhus  fever  were  wfell  marked,  except, 
instead  of  constipation  being  present,  the  bowels  were 
loose,  the  patient  having  from  three  to  four  passages 
daily,  and  the  faeces  being  of  a  fetid  character  and  of  a 
spinach-green  color ;  precisely  similar  in  looks  to  that  of 
Case  II.  There  was  also  present  from  the  very  onset  of 
the  disease  a  peculiar  symptom,  and  one  not  very  fre- 
quently seen,  namely,  intense  nausea  and  vomiting,  the 
ejecta  varying  in  color  from  a  dirty  brown  to  a  pea-green. 
This  symptom  lasted  without  any  abatement  up  to  the 
time  of  the  patient's  death,  which  occurred  forty-eight 
hours  after  his  admission.  The  temperature  was  very 
high  from  the  beginning,  the  maximum  point  reached  by 
the  thermometer  being  io5f°;  the  muscular  hyperaes- 
thesia  was  well  marked,  but  the  delirium  and  coma  were 
not  as  great  as  we  should  have  been  led^  to  expect  from 
the  gravity  of  the  other  symptoms.  Retention  of  urine 
was  also  present. 

On  post-mortem  the  viscera  were  found  to  be  all 
deeply  congested.  The  stomach  showed  decided  evi- 
dences of  chronic  gastritis,  superinduced  no  doubt  by 
the  patient's  intemperate  habits.  The  liver  was  in  a  far 
advanced  stage  of  '*  interstitial  hepatitis."  The  ileum 
showed  in  many  places  the  "  shaven-beard "  appearance 
of  the  mucous  membrane. 

Case  XI. — John  W ,  twenty-six  years  of  age,  col- 
ored ;  admitted  to  the  hospital  April  7, 1883.  The  patient 
was  a  pauper  inmate  of  the  institution  when  attacked  by 
the  disease,  and  as  an  assistant  attendant  in  the  typhus 
wards,  was  directly  exposed  to  contagion.  The  writer 
would  here  mention  that  this  was  by  no  means  the  only 
case  of  typhus  fever  which  arose  from  contact  with  the 
sick,  for  the  two  men  whose  duty  it  was  to  carry  the 
patients  from  the  ambulance  to  the  wards,  and  the  dead 
to  the  dead-house,  both  contracted  typhus  fever,  and  one 
died.  This  patient  was  first  seized  with  a  well-marked 
chill,  followed  by  some  nausea,  the  temperature  quickly 
rose,  until  at  the  beginning  of  the  third  day  it  reached 
103^*'.  The  delirium,  which  was  at  first  but  slight,  increased 
in  severity  up  to  the  fifth  day ;  it  was  not  of  the  usual 
low  character,  but  was  of  the  active,  busy  type  some- 
times seen  in  typhoid  fever.  The  bowels  were  exceed- 
ingly constipated,  and  the  urine  scanty,  and  of  a  high 
color,  containing  a  small  amount  of  albumen  ;  a  condi- 
tion of  rare  occurrence  in  this  epidemic,  not  even  a  trace 
having  before  been  detected  in  the  twenty-seven  cases 
whose  urine  the  writer  examined. 

It  is  proper  to  state  that  this  condition  of  slight  albu- 
minuria was  not  a  constant  feature  even  in  this  case ;  it 
disappeared  on  the  eleventh  day,  and  did  not  again  re- 
turn. 

The  hyperaesthesia  was  well  marked  and  persistent, 
the  pulse  hard  and  rapid,  and  the  tongue  cracked  and 
fissured  in  numerous  places,  of  a  dark  brown  hue  with  a 
red  and  angry-looking  tip. 

These  symptoms  continued  with  more  or  less  severity 
until  the  thirteenth  day,  with  exception  of  the  tempera- 
ture alone,  which  was  reduced  to  ioi|°  by  the  sixth  day, 
above  which  point  it  never  again  rose.  Immediately  a  de- 
cided amelioration  in  the  symptoms  occurred,  and  by  the 
end  of  the  third  week  convalescence  was  fully  established. 
Some  ten  days  later  the  patient  was  discharged  cured. 

Case  XII. — George    H ,   aged  nineteen,  white, 

admitted  April  15,  1883.  This  was  the  only  patient  of 
the  nineteen  which  fell  to  the  writer's  care  (exclusive  of 
the  two  which  originated  in  the  institution)  which  did 
not  come  from  the  infected  locality  of  the  city  so  often 
referred  to  in  the  preceding  pages. 

The  patient  was  of  respectable  parentage,  and  as  far 
as  could  be  determined  was  under  good  sanitary  and  hy- 
gienic surroundings  prior  to  his  attack.  His  illness  dated 
about  four  days  prior  to  his  admission  to  the  hospital, 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


341 


and  was  attended  by  a  physician  in  the  northern  section 
of  the  city,  who  recognized  the  nature  of  the  case  and 
by  whose  advice  he  was  sent  to  the  hospital.  When  first 
seen  he  was  in  a  state  of  profound  coma  ;  the  eruption, 
although  not  abundant,  was  still  quite  noticeable  on  the 
abdomen  and  lower  extremities;  the  hyperaeslhesia  of 
the  muscles  quite  distinct ;  the  pulse  rapid,  but  weak 
and  feeble,  and  the  temperature  registered  io4f°.  The 
breath  was  very  fetid,  the  teeth  covered  with  sordes,  the 
tongue  dry,  cracked,  and  of  the  usual  dark  brown  hue 
almost  to  the  tip.  The  bowels  were  costive,  and  the 
urine  had  to  be  drawn  oflf  by  the  catheter. 

The  patient  rapidly  and  progressively  grew  worse,  the 
coma  deepened,  the  respiration  became  more  and  more 
shallow,  the  heart's  action  more  feeble,  and  death 
finally  occurred  some  thirty  hours  after  his  admission. 

The  autopsy  revealed  deep  congestion  of  all  the  vis- 
cera, particularly  of  the  lungs  and  kidneys,  and  the  char- 
acteristic pathological  appearances  were  noticed  in  the 
ilium.  The  coqdition  of  the  brain  was  normal,  except  a 
slight  increase  of  the  "  puncta  vasculosa.'*  The  cerebro- 
spinal fluid  was  about  normal  in  quantity. 

Case   XIII. — George  A ,  aged  forty,  white,  ad-' 

niitted  April  26th.  A  pauper  inmate  of  the  out- wards  of 
the  Almshouse,  who,  as  far  as  could  be  learned,  had  not 
been  directly  exposed  to  contagion.  His  case  proved  to 
be  of  a  lighter  type  than  usually  seen  during  this  epi- 
demic, and  although  all  the  symptoms  of  typhus  fever 
were  present,  still  they  were  all  of  a  mild  degree.  The 
eruption  occurred  late,  and  was  very  light.  He  became 
convalescent  about  the  fourth  week  and  soon  after  was 
discharged  cured. 

Case  XIV. — ^Thomas  McG ,  aged  fifty-one,  white, 

admitted  May  3d.  No  history  of  this  case  could  be  ob- 
tained from  the  patient,  owing  to  his  condition,  but  his 
friends  living  in  the  locality  from  which  he  was  brought 
(Seventh  and  St.  Mar/s  Streets)  told  the  ambulance 
doctor  that  he  had  been  in  the  condition  in  which  he 
then  was  nearly  three  days.  This  case  differed  in  no 
respect  from  other  severe  ones  of  the  epidemic,  except 
that  the  fever  was  protracted  to  the  end  of  the  fourth 
week,  and  convalescence  was  extremely  slow,  it  being 
nearly  two  months  before  he  was  able  to  walk  even  a 
short  distance  unassisted.  Diarrhoea  was  i)resent  up  to 
the  end  of  the  third  week. 

Case    XV.— Charles  S ,  aged  forty-three,  white, 

admitted  May  21st.  The  disease  as  in  many  others  cases 
during  this  epidemic  was  ushered  in  with  a  severe  chill. 
The  temperature  arose  on  the  third  day  to  I03J^  and 
remained  at  that  point  until  the  fifth  day,  when  tor  one 
day  it  slightly  declined.  The  pulse  was  hard  and  rapid, 
registering  with  but  little  variation  about  138  beats  per 
minute.  The  delirium  was  of  a  more  violent  type  than 
usual,  and  continued  so  up  to  the  time  of  his  death.  The 
urine  was  scanty  and  high  colored,  rich  in  urea  and  the 
urates,  a  few  tube  casts  being  also  noticed.  The  bowels 
were  rather  loose,  and  the  faeces  of  a  dark  green  color 
and  very  fetid.  The  eruption,  which  was  quite  copi- 
ous, made  its  appearance  on  the  fifth  day.  The  exhaus- 
tion and  debility  of  the  patient  was  very  marked,  and  the 
emaciation  was  undoubtedly  greater  than  presented  by 
any  other  case  of  the  epidemic ;  this  might  be  accounted 
for  by  the  exhausted  constitution  of  the  patient  prior  to 
the  inception  of  the  disease. 

After  the  fifth  day  the  man  began  rapidly  to  grow 
weaker  and  weaker,  the  stomach  rejected  both  food  and 
medicine,  except  in  the  minutest  quantities,  and  the 
temperature,  despite  all  remedies,  remained  at  105°.  He 
died  on  the  ninth  day  in  a  state  of  complete  coma. 

On  post-mortem  examination  the  viscera,  as  in  the 
other  cases,  showed  evidences  of  deep  congestion ;  the 
intestines  revealed  the  characteristic  "shaved  beard" 
appearance  of  the  mucous  membrane ;  the  kidneys  were 
far  advanced  in  parenchymatous  nephritis,  and  the  brain, 
beyond  a  slight  superficial  congestion,  showed  no  abnor- 
mality. 


Cases  XVI.  and  XVII.— Patrick  S and  Michael 

McG ,  aged  respectively  thirty-nine  and  twenty- 
eight,  white,  both  admitted  May  26,  1883.  ^^^  cases, 
as  far  as  could  be  ascertained,  were  taken  ill  about  the 
same  day,  and  were 'brought  from  the  vicinity  of  Sixth 
and  Lombard  Streets.  The  eruption  appeared  in  both 
men  on  the  seventh  day,  quite  plent^ully  in  the  first 
patient,  but  rather  scanty  in  the  second ;  the  temperature 
was  never  very  high  in  either — the  maximum  being  io2.f  ^; 
the  delirium  was  not  marked,  and  by  the  twelfth  day 
their  intellects  were  perfectly  clear.  The  bowels  in  each 
were  inclined  to  constipation.  At  the  end  of  the  fourth 
week  convalescence  was  fully  established,  and  soon  after 
they  were  discharged  cured. 

Cases  XVIII.  and  XIX. — Nothing  of  particular  in- 
terest was  noticed  in  either  case,  all  the  symptoms  being 
well  developed,  but  of  a  light  type.  Recovery  occurred 
in  both  cases  toward  the  end  of  the  fourth  week. 

The  writer  has  postponed  a  recapitulation  of  the  treat 
ment  of  the  cases  presented  in  this  epidemic  until  the 
symptoms  and  pathological  conditions  of  each  could  be 
given  in  detail ;  for  the  treatment  pursued,  with  but  few 
exceptions  to  meet  certain  emergencies,  being  well-nigh 
similar,  it  would  be  a  work  of  supererogation  to  state  it  in 
extenso  in  each  case. 

From  the  very  commencement  it  was  found  necessary  to 
stimulate  and  support  the  patient,  attention  at  the  same 
time  being  given  to  the  secretions,  and  means  taken  to 
arrest  hyperpyrexia  and  hold  in  check  excessive  delirium. 
Free  stimulation  with  whiskey  or  brandy,  preferably  the 
former  was  necessary  from  the  onset,  and  the  amount  re- 
quired was  found  to  be  about  one  ounce  every  three 
hours  for  the  first  three  days,  and  subsequently  increased 
by  giving  the  same  quantity  every  two  hours,  and  as 
convalescence  became  assured  the  interval  was  again 
lengthened.  There  can  be  no  doubt  that  our  chief  reme- 
dial agent  in  this  epidemic  was  alcohol,''and  without  its 
use  the  mortality  would  have  been  greatly  increased. 

Much  attention  was  paid  to  the  administration  of  easily 
digested  and  nourishing  food.  A  strict  adherence  to  a 
liquid  dietary  is  not  necessaxy,  indeed  occasional  indul- 
gence in  easily  assimilated  solid  food  is  not  only  beneficial 
but  strongly  indicated.  Milk,  eggs,  strong  animal  broths, 
arrowroot,  rice,  etc.,  were  administered  with  regularity, 
the  patient  taking  nourishment  in  some  form  every  two 
hours  by  day,  and  three  hours  by  night,  even  arousing 
him  from  sleep  for  the  purpose.  Small  amounts  of  solid 
food,  as  finely  chopped  sweetbread,  rare  tender  beef,  or 
chicken,  were  occasionally  given,  but  care  was  exercised 
that  nourishment,  whether  liquid  or  solid,  was  taken  only 
in  small  quantities  at  one  time. 

Aconite  and  veratrum  viride  have  been  recommended 
by  some  authorities  as  the  most  useful  and  potent  reme- 
dies we  possess  for  the  excessive  hyperpyrexia,  and 
although  the  writer  does  not  for  a  moment  deny  the 
wonderful  power  of  these  two  agents  in  controlling  car- 
diac action  and  reducing  the  temperature  of  the  body, 
nevertheless  in  his  ^experience  they  have  both  proven 
entirely  too  depressing  in  their  action  for  a  disease  of 
this  character.  The  use  of  quinine  in  ten-grain  doses 
four  times  daily,  along  with  the  following  prescription,  is 
attended  with  much  more  beneficial  results : 

$.  Tincturse  digitalis f  3  ij. 

Spts.  aether,  nit f  3  jss. 

Liq.  potass,  cit., 

Liq.  ammon.  acetat &a  f  |  ji. 

Aquae q.  s.  ad  f|vj. 

M.    Fiat  mistura.     Sig. — Tablespoonful  every  three 
hours. 

These  remedies  along  with  frequent  sponging  with  cool 
water,  a  small  amount  of  vinegar  or  bay  rum  being  added, 
seldom  failed  in  the  experience  of  the  writer  to  reduce 
the  highest  temperatures. 

Some  authors  have  recommended  in  cases  of  great  and 
persistent  hyperpyrexia  the  immersion  of  the  patient  in  a 


342 


THE  MEDICAL  RECORD. 


[September  27,  1884, 


cold  bath  ;  but  this  is,  to  say  the  least,  a  practice  attended 
with  the  greatest  danger,  and  should  only  be  resorted  to 
in  the  most  desperate  cases,  and  then  only  when  all 
other  means  have  been  tried  and  failed.  The  writer  cm- 
ployed  the  cold  bath  treatment  but  -in  one  case,  and  then 
only  used  it  after  having  tried  all  other  remedies  without 
avail.  The  beneficial  effects  of  the  bath  were  very  tran- 
sient ;  a  reduction  of  2^°  having  occurred  immediately 
after  the  immersion,  but  scarcely  had  a  half  hour  elapsed 
before  the  thermometer  registered  \°  higher  than  before 
the  bath.  The  operation  was,  however,  repeated,  but 
with  the  same  unsatisfactory  results. 

Chlorine  water  was  extensively  employed  by  Dr.  Lud- 
low in  his  cases,  but  with  no  very  encouraging  results, 
although  in  a  few  instances  it  was  claimed  that  consider- 
able benefit  was  derived  from  its  use.  It  is  an  old  remedy 
for  the  disease,  and  was  originally  brought  forward  on 
account  of  its  supposed  specific  effects ;  but  the  history  of 
this  epidemic,  as  well  as  those  which  have  preceded  it, 
conclusively  prove  that  there  is  no  specific  for  typhus ; 
or  in  other  words,  therapeutists  have  not  yet  discovered 
any  article  that  may  be  considered  directly  antagonistic 
to  the  disease.  The  sulphites  have  also  been  employed 
as  supposed  specifics,  but  with  the  same  results.  Chloral 
and  bromide  of  potassium,  in  a  mixture  containing  ten 
grains  of  the  former  to  twenty  grains  of  the  latter,  proved 
very  efficacious  in  abating  the  delirium  when  active  and 
exhaustive  to  the  patient.  The  writer  exclusively  used 
a  combination  of  the  oleoresin  of  lupulina,  VI  xv.,  and  the 
tincture  of  cannabis  indica,  VI  xx. ,  for  such  cases,  and  can 
testify  to  its  great  utility.  Belladonna  is  also  strongly 
recommended  by  some  authors,  and  is  particularly  ad- 
vantageous in  those  cases  characterized  by  low  muttering 
delirium.  Opium  should,  as  far  as  possible,  be  avoided 
in  all  cases.  If  constipation  is  persistent,  an  occasional 
laxative  should  be  employed,  and  the  writer  knows  of 
none  which  so  well  answers  the  purpose  as  the  ordinary 
sulphate  of  magnesia,  or  Epsom  salts.  The  use  of  the 
mineral  acids,  especially  nitro -muriatic,  in  ten-minim  doses 
is  possibly  of  some  utility,  and  may  be  combined  with  the 
quinine  treatment  referred  to  above.  If,  as  sometimes 
occurs,  the  kidneys  cease  to  excrete  the  proper  amount  of 
urea,  and  as  a  consequence  ursemic  coma  is  threatened, 
sinapisms  over  the  renal  region,  and  vesication  of  the 
nucha  are  called  for. 

Bed-sores,  which  frequently  occur  during  the  course  of 
the  disease,  are  beneficially  treated  at  first  by  a  lotion  of 
alcohol  and  alum,  but  when  fully  developed  carbolized 
oil  is  best  used  instead 

In  view  of  the  contagious  character  of  the  disease, 
typhus  cases  should  not  be  treated  in  hospital  wards  with 
other  patients.  If  overcrowding;  be  prevented  and  free 
ventilation  secured,  the  fever  miasm  is  not  as  easily  gen- 
erated, nor  is  the  disease  as  likely  to  be  communicated. 
Extreme  cleanliness,  both  of  the  patient  and  the  wards, 
along  with  the  free  use  of  disinfectants,  such  as  carbolic 
acid  and  chlorinated  lime,  are  hygienic  measures  of  great 
importance. 

Mortality, — Although  the  average  mortality  is  gener- 
ally placed  at  from  eighteen  per  cent,  to  twenty-five  per 
cent,  in  this  epidemic  it  reached  at  least  thirty-three  per 
cent.,  but  as  age  greatly  modifies  both  the  prognosis  and 
mortality  (the  disease  not  being  a  very  fatal  one  before 
the  twentieth  year),  and  as  seventy-five  per  cent,  of  all 
our  cases  were  between  thirty  and  thirty- five  years  old, 
and  many  ranged  between  forty-five  and  fifty-five,  a  very 
important  factor  in  increasing  the  mortality  of  this  epi- 
demic was  thus  produced.  It  is  also  but  just  to  say  that 
at  least  nine-tenths  of  all  our  patients  were  persons  de- 
bilitated and  exhausted  by  every  vice,  and  most  of  them 
exposed  from  childhood  to  most  unhygienic  surroundings. 

Chemical  Euphemism. — Few  people  are  aware,  01 
seriously  consider  that  when  they  take  a  cup  of  tea  it 
is  essentially  an  aqueous  solution  of  trimethybcanthine 
(CgHj^N^OJ  which  they  are  drinking. 


CEREBRAL    LOCALIZATION— THE    CENTRES 
FOR  VISION. 

BV  PHILIP  ZENNER,  A.M.,  M.D., 

cmaNNATi,  o. 

(Coadnued  from  p.  335.) 

Pathological  data.—Our  investigations  in  this  third  line 
of  research  will  not  lead  us  to  as  exact  results  as  either 
our  anatomical  or  physiological  studies.  But  they  are, 
nevertheless,  the  most  valuable  in  promoting  the  main 
object  we  have  in  view,  cerebral  localization  in  man,  and 
are  quite  sufficient  to  arrive  at  definite  results. 

Impainnent  of  vision  may  be  caused  by  lesions  of  any 
part  of  the  intracranial  visual  apparatus,  or  by  lesions  of 
indifferent  portions  of  the  brain,  as  optic  neuritis  so  fre- 
quently attends  any  coarse  cerebral  disease.  But  as  we 
are  seeking  for  the  centre  of  vision  in  the  cerebral  hemi- 
spheres, visual  disturbances  will  only  interest  us  where 
they  appear  to  be  directly  produced  by  lesions  of  limited 
portions  of  the  hemispheres.  To  obtain  such  cases  we 
must  be  able  to  eliminate  general  causes,  as,  for  instance, 
optic  neuritis,  dependent  upon  increased  intracranial 
pressure,  and  the  visual  symptoms  produced  by  involve- 
ment of  the  more  peripheral  parts  of  the  visual  appara- 
tus, the  optic  nerves,  chiasma,  and  tracts,  and  the  basal 
ganglia,  optic  thalami,  corpora  quadrigemina,  and  genicu- 
kte  bodies. 

A  number  of  such  cases  have  been  reported.  In  all 
of  them  there  was  disease  of  the  occipital  lobes,  the  part 
which  we  have  already  been  taught  to  consider  the 
chief,  if  not  the  only  seat  of  the  centre  for  vision.*  In 
all  of  these  cases  the  same  kind  of  disturbance  of  vision 
was  found,  loss  or  impairment  of  vision  on  one  side, 
homonymous  lateral  hemianopia.* 

As  this  symptom  is  so  important  for  us  in  this  connec- 
tion, we  will  dwell  briefly  upon  it.  There  is  an  obscura- 
tion or  entire  defect  of  one-half,  or  approaching  one-half, 
of  the  field  of  vision,  due  to  a  loss  of  sensibility  on  the 
corresponding  sides  of  both  retinae.  Lesions  of  one 
hemisphere  cause  loss  of  sensibility  of  the  retinae  on  the 
same  side,  and  blindness  in  the  field  of  vision  of  the  op- 
posite side.  Thus  a  lesion  in  the  left  occipital  lobe  is 
attended  by  paralysis  of  the  left  half  of  each  retina,  and 
blindness  of  the  right  half  of  the  field  of  vision,  or  right 
hemianopia.  It  is  to  be  remembered  then,  when  we  say 
right  or  left  hemianopia,  we  are  describing  the  side  on 
which  the  patient  does  not  see,  and  that  it  betokens  dis- 
ease of  the  opposite  side  of  the  brain.' 

Of  the  cases  of  disease  of  a  cerebral  hemisphere  with 
accompanying  hemianopia  some  cannot  be  utilized  for 
our  present  purposes  for  reasons  already  mentioned,  be- 
cause the  disease  is  very  extensive,  and  especially  because 
it  involves  the  basal  ganglia,"  or  because  there  were  at 
the  same  time  changes  m  the  optic  nerves ;  *  others, 
because  the  lesion  was  of  too  recent  date,'  or  because 
the  examination  was  not  made  with  sufficient  exactness, 
or,  at  least,  was  not  sufficiently  detailed  in  the  report* 

We  will  proceed  to  the  mention  of  the  individual  cases 
which  can  be  utilized  in  the  present  investigation.  Each 
one  will  be  given  as  briefly  as  is  consistent  with  our 
present  object. 

In  a  case  of  Baumgartner '  a  complete  left  hemianopia 
appeared  suddenly  and  remained  until  death.  The  post- 
mortem examination  revealed  "  an  old  apoplectic  cyst, 

>  There  is,  to  far  at  I  know,  but  one  apparent  exception  to  this  statement,  a  esse 
of  Hufenin  (Ziemssen,  xi.,  p.  816).  where  a  lesion  was  found  only  in  the  animar 
part  of  the  (lanetal  lobe.  But  as  the  disease  extended  into  the  subcortical  medul- 
larv  matter  it  probabljr  reached  to  the  optic  radiations. 

*  The  terms  hemiopi^  hemianopia,  and  hemianopsia  are  all  used  to  express  dw 
same  condition.  The  oldest  one,  nemiopia,  is  becoming  less  and  less  used.  Tne 
term  hemianopia  will  be  alone  used  in  this  paper. 

»  Cases  of  Pooley  (Archives  of  Ophth..  v.,  o.  148)  ;  Vetter  (DeuU  Archiv.  £  kL 
Med.,  xxxii.,  p.  507) ;  Hosch  (Zehnder's  Monatsblatt,  1878,  p.  285) ;  Wonida 
(Gehim  Krankheiten,  iu,  p.  70J  ;  Prevost,  Fritach,  Chaallou,  and  Chvosldc  (ated 
by  Wilbrand.  Ueber  Hemianopsie). 

*  Cases  of  Jany  (Archives  of  Ophth.,  xii.,  p.  9j»)  ;  Haab(Zehndet's  MooatsWatt, 
1882,  p.  141)  :  Gnesinger  (>yilbrand,  p.  154)* 

•  Case  of  Dmitrowsky  (Wilbrand,  p.  139). 

•  Cases  of  Lewick  (American  Journal  of  the  Medical  Sdenccs,  1866.  p.  413K 
Nothnagel  (Topische  Diagnosak,  p.  4");  Frilsch,  Traube,and  Putschcr  (wi- 
brand). 

'  Centralblatt  f.  d.  Med.  Wissenschaften,  1878,  p.  369. 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


343 


the  size  of  a  walnut,  in  the  right  occipital  lobe.  Its  inferior 
wall  was  separated  from  the  cavity  of  the  right  posterior 
cornua  by  a  layer  of  healthy  tissue  several  millimetres  in 
thickness.  The  superior  wall  was  formed  by  the  three 
occipital  convolutions,  which  were  altogether  softened. 
There  was  also  a  focus  of  softening,  the  size  of  a  pea,  in 
the  roof  of  the  left  anterior  cornua,  and  an  apoplectic  cica- 
trix, scarcely  half  the  size  of  a  lentil  seed,  in  the  centre 
of  the  right  thalamus.  Optic  nerves,  tracts,  and  chiasraa, 
and  geniculate  bodies  and  corpora  quadrigemina  were 
normal"  The  lesions  in  the  thalamus  and  anterior 
cornua  may  be  ignored,  as  we  know  they  could  not  have 
produced  the  symptoms.  We  need  not,  therefore,  hesi- 
tate to  conclude  that  the  hemianopia  was  here  due  to  the 
disease  in  the  occipital  lobe. 

A  case  of  Westphal  ^  had  occasional  attacks  of  uni- 
lateral convulsions  for  a  number  of  years  before  death. 
He  had  also  a  complete  left  hemianopia.  The  post- 
mortem  examination  revealed  a  focus  of  softening  in  the 
right  occipital  lobe,  which  extended  into  the  parietal  lobe 
and  the  bordering  temporal  convolution.  The  softening 
was  in  the  medullary  substance,  the  cortex  being  unaf- 
fected. The  motor  regions  of  the  hemispheres,  the  in- 
ternal capsules,  large  ganglia,  and  optic  tracts  were  nor- 
mal 

In  a  man  of  seventy- two,  reported  by  Marchand,'  with 
complete  left  hemianopia  and  hemiplegia  there  were 
found  destructive  changes  in  the  occipital  lobe,  and  also 
a  degree  of  softening  of  the  cortex  in  parts  between  the 
occipital  lobe  and  the  fissure  of  Rolando. 

In  Curschman's  *  case  there  was  complete  left  hemia- 
nopia without  other  cerebral  symptoms.  Post-mortem 
examination  revealed  "  a  large  focus  of  softening  in  the 
right  occipital  lobe,  which  reached  to  the  surface,  chiefly 
in  the  superior  surface  and  apex  of  this  lobe.'*  Rest  of 
brain  normal. 

In  a  case  of  Haab  *  a  woman  of  sixty-one,  had  com- 
plete left  hemianopia,  with  scarcely  any  other  cerebral 
symptom,  for  one  year  before  her  death.  On  post-mor- 
tem examination  there  was  found  softening  of  the  right 
occipital  lobe,  especially  its  median  surface.  The  cortex 
was  chiefly  affected,  but  the  softening  extended  deeply 
into  the  medullary  substance,  though  it  did  not  reach  as 
far  as  the  posterior  cornua. 

The  foregoing  cases  prove  that  hemianopia  may  be 
produced  by  disease  of  tiie  hemispheres  which  does  not 
involve  the  primar}'  visual  centres  (optic  thalami,  genicu- 
late bodies,  and  corpora  quadrigemina)  or  the  more 
peripheral  visual  apparatus.  They  prove  also  that  this 
symptom  is  caused  by  disease  of  the  cerebral  cortex.  For, 
though  in  all  of  these  instances  the  subcortical  medullary 
substance  was  affected,  we  know  that  nerve-fibres  are  not 
centres  for  functions,  that  they  merely  serve  to  convey  im- 
pressions and  impulses  ;  and  that,  therefore,  in  the  above 
instances  their  involvement  could  only  have  produced 
symptoms  through  cutting  off  the  communication  with  the 
cortex* 

The  cortex,  then,  is  the  centre  for  sight.  But  to  what 
part  of  the  cortex  this  function  belongs  is  not  so  defi- 
nitely answered  by  these  instances,  for  we  cannot  say 
to  just  what  extent  the  symptom  was  here  due  to  destruc- 
tion of  the  white  subcortical  substance,  nor  do  we  know 
in  exactly  what  area  of  the  cortex  the  destroyed  fibres 
found  their  final  distribution.  But  as  in  these  instances 
the  disease  was  chiefly  or  entirely  in  the  posterior  parts 
of  the  hemispheres,  it  is  rendered  probable  from  them  that 
the  cortical  visual  centre  is  in  the  posterior  part  of  the 
brain.  This  conclusion  is  further  corroborated  by  other 
and  more  striking  instances.  But  before  considering  the 
latter  we  will  briefly  mention  a  few  reported  cases  which, 
though  less  convincing  than  those  just  given,  still  have 
some  weight  in  the  above  conclusion. 

*  Cbarit^  Annaleii,  w.  i  cited  by  Wernicke*  Gchirnkrankheiten,  ii.,  p.  195. 

*  Axx:hiv.  f.  Ophthal.,  xxviii.,  a. 

'  Centnlbtati  Auffenheilkunde.  1879,  p.  x8i.     i 

*  Zchnder's  Monatsblatt,  1882,  p.  149. 


In  a  case  of  Stenger,'  with  occasional  left-sided  convul- 
sions, temporary  left  hemiplegia,  and  left  hemianopia, 
which  remained  permanently  during  the  last  six  months 
of  life,  there  was  found,  in  addition  to  an  internal  hydro- 
cephalus and  slight  general  charges  in  the  brain,  decided 
lesions  in  the  right  occipital  and  parietal  lobes. 

In  a  second  case  of  Stenger '  there  were  occasional 
unilateral  convulsions,  right  hemianopia,  first  observed 
four  months  before  death  and  remaining  permanently, 
and  about  one  month  before  death  also  a  left  hemiano- 
pia, so  that  the  patient  was  now  completely  blind.  The 
post-mortem  examination  revealed  slight  general  changes 
both  in  the  meninges  and  in  the  brain,  and  decided 
atrophy  of  both  occipital  lobes,  that  in  the  left  being 
apparently  of  older  date. 

In  both  of  these  instances  the  general  changes  in  the 
brain,  as  well  as  the  clinical  histories,  were  like  those  of 
general  paralysis.  But  inasmuch  as  in  general  paraly- 
sis the  pathological  changes  are  usually  slight,  and  the 
localizing  symptoms  slight  and  transitory,  and  in  the 
above  instances  the  visual  defect  was  both  complete 
and  lasting,  and  the  only  decided  lesions  those  in  the 
parts  mentioned,  it  is  highly  probable  that  these  lesions 
and  symptoms  were  in  direct  relation  with  each  other. 

In  a  case  of  Wernicke,*  there  was,  in  addition  to  cer- 
tain disturbances  of  speech,  a  right  hemianopia,  which 
existed  for  twenty  months  before  death.  There  was 
found  extensive  disease  of  the  left  hemisphere.  The 
rest  of  the  brain  appeared  to  be  normal  excepting  that  a 
part  of  the  left  corpus  striatum  was  softened,  and  the 
optic  thalamus  seemed  a  little  reduced  in  size. 

The  lesion  in  the  corpus  striatum  could  not  have 
produced  hemianopia,  and  the  changes  in  the  thalamus 
were  apparently  too  trivial  to  account  for  the  visual  dis- 
turbance. 

In  Nothnagel's  *  case  .there  was  right  hemianopia  and 
extensive  destruction  of  the  cortex  of  the  left  occipital 
lobe.  But  there  were  also  motor  symptoms  and  lesions 
in  the  anterior  parts  of  the  brain,  so  that  the  observation 
has  only  a  problematic  value. 

In  a  case  of  Jastrowitz,*  with  right  hemianopia  (fundi 
oculi  normal),  a  large  part  of  the  posterior  part  of  the 
left  hemisphere  was  destroyed  by  a  tumor,  which  reached 
to  the  level  of,  but  did  not  implicate,  the  optic  thalamus. 
The  rest  of  the  brain,  ganglia  at  base,  optic  tracts,  etc., 
was  normal. 

There  might  be  some  hesitancy  in  admitting  this  case 
as  evidence,  because  of  a  tumor  which  usually  produces 
general  symptoms,  symptoms  due  to  increased  intracra- 
nial pressure.  But  hemianopia  is  a  symptom  of  such 
local  significance,  and  there  is  nothing  to  explain  it  in 
this  case  but  the  local  lesion,  so  that  this  case  has  prob- 
ably as  much  value  as  those  just  preceding  it. 

The  five  cases  just  given,  notwithstanding  the  impos- 
sibility of  definite  conclusions  where  each  one  is  criti- 
cally examined  by  itself,  have  still,  when  taken  together, 
a  certain  value  in  the  solution  of  our  problem. 

Of  far  more  value,  perhaps  the  most  valuable  of  those 
yet  recorded,  is  the  case  to  be  now  mentioned,  the 
second  one  of  Westphal,  reported  in  the  Chariti  Annalen, 
1882.*  In  this  case  there  was,  in  addition  to  occasional 
right  unilateral  convulsions  and  disturbances  of  speech, 
an  impairment  of  the  muscular  sense  in  the  right  arm  and 
hand,  and  a  right  hemianopia,  which  existed  from  the 
time  of  the  first  observation,  October,  1879,  to  the  time 
of  death,  December,  1881.  There  was  found,  post 
mortem,  disease  of  the  cortex  over  the  greater  part  of 
the  occipital  lobe,  the  parietal  lobe,  including  the  pos- 
terior central  convolution,  and  a  small  part  of  the  tem- 
poral lobe.  The  disease  did  not  extend  into  the  sub- 
cortical medullary  substance. 

>  Achiv.  f.  Psychiatric,  xiii.,  p.  046. 

3  Ibid.,  p.  a49* 

*  Gehirn  Krankheitoi,  iL,  p.  190. 

4  Topische  Diagnostik,  p.  389. 

•  Centralblatt  Augenheilkunde,  1877,  p.  254. 
«  Brain,  1889,  p.  281. 


344 


THE  MEDICAL  RECORD. 


[September  27,  i884. 


This  case  proves,  what  we  had  already  concluded  from 
previous  cases,  that  there  is  a  visual  centre  in  the  cor- 
tex. As  regards  its  exact  localization  it  does  not  lead  us 
beyond  our  former  conclusions,  that  the  visual  centre  is 
in  the  posterior  part  of  the  hemispheres. 

I  will  next  mention  two  cases  in  which  hemianopia 
followed  traumatic  injury  of  the  brain. 

The  first  case  was  a  man,  aged  twenty-three,  wounded 
at  the  battle  of  Antietam.  According  to  the  account  of 
Surgeon  McCall,'  the  ball  passed  from  about  one  inch 
above  the  occipital  protuberance  into  the  cavity  of  the 
cranium  and  emerged  at  a  point  to  the  left  of  the  median 
line  about  an  inch  and  three-quarters  from  the  point 
of  entry.  There  was  temporary  paralysis  of  right  arm 
and  leg.  Keen  and  Thompson'  made  a  careful  ex- 
amination eight  years  after  the  injury.  Fundi  oculi  were 
normal.  Central  vision,  and  vision  in  left  half  of  field 
were  normal,  while  in  the  right  of  the  field  of  vision 
there  was  complete  blindness.  The  blind  field  reached 
to  a  vertical  line  passing  through  the  point  of  fixation. 
Only  at  the  latter  point  there  appeared  to  be  a  very 
slight  bending  of  the  line  toward  the  affected  side. 

Nieden  *  reported  the  following  interesting  case,  which, 
at  the  time  of  his  last  report,  in  the  latter  part  of  1883, 
was  still  under  observation.  A  young  woman  of  twenty- 
two  sustained  a  severe  injury  in  the  occipital  region  from 
a  fall.  Notwithstanding  the  continuance  of  headache 
and  slight  paralytic  symptoms,  she  attended  to  her  ordi- 
nary household  duties  until  about  seven  months  after 
the  injury,  when,  on  account  of  the  supervention  of 
serious  symptoms,  mental  disturbance,  convulsions,  etc  , 
operative  interference  was  resorted  to.  There  was  at 
this  time  slight  paralysis  of  the  right  arm  and  leg,  but 
vision,  which  had  been  repeatedly  and  carefully  ex- 
amined, was  altogether  normal.  TTie  trephine  was  ap- 
plied, and  a  button  of  bone  removed,  just  to  the  left  of 
the  sagittal  suture,  and  one-half  centimetre  above  the 
external  occipital  protuberance. 

This,  according  to  the  calculation  of  Nieden,  was  just 
over  the  apex  of  the  occipital  lobe.  During  the  operation 
the  dura  mater  was  injured  and  subsequently  brain-sub- 
stance protruded  through  the  opening  in  the  bone. 

The  second  day  after  the  operation  it  was  noted  that 
the  paralysis  and  anaesthesia  of  the  arm  were  diminished, 
but  that  the  patient  spoke  of  a  cloud  before  the  eves,  es- 
pecially on  the  right  side.  Subsequently  the  patient  en- 
tirely recovered  from  the  paralysis,  headache,  etc.,  but 
the  disturbance  of  vision  remamed  permanently.  As 
soon  as  a  careful  examination  could  be  made  it  was  noted 
that  in  the  right  eye  the  whole  of  the  temporal  field  of 
vision  and  a  part  of  the  upper  median  field  were  missing, 
and  that  central  vision  was  impaired.  In  the  left  eye 
central  vision  was  perfect,  but  there  was  a  slight  con- 
centric contraction  of  the  field.  A  year  subsequent  to 
the  time  of  injury  central  vision  in  the  left  eye  was  still 
perfect,  but  one-third  of  its  median  field  was  missing. 
This  was  attributed  to  the  cicatrization  of  the  wound  m 
the  occipital  lobe  causing  further  destructive  changes  in 
a  part  of  that  lobe  which  had  hitherto  functioned  for  the 
inner  part  of  tlie  left  retina. 

Though  no  post-mortem  examination  was  made  there 
could  scarcely  be  better  evidence  of  cerebral  localization 
than  this  case.  The  impairment  of  vision  wa«  the  im- 
mediate result  of  an  injury  of  the  surface  of  the  brain,  in 
just  that  locality  where  such  a  result  might  be  expected, 
but,  besides  that,  the  visual  disturbance  followed  the  in- 
jury inunediately,  no  other  cerebral  symptoms  appeared, 
in  fact,  those  previously  existing  began  immediately  to 
<iisappear,  so  that  the  visual  symptoms  cannot  be  at- 
tributed to  any  general  injury  or  involvement  of  distant 
l>arts,  but  is  a  direct  expression  of  local  changes. 

The  last  three  cases  are  almost  positive  proof  of  the 
general  conclusion  above  drawn,  that  there  is  a  cortical 

>  Medical  and  Surgical  History  of  the  War,  Part  I.,  vol.  ii.,  p.  ao6. 
*  Trans,  of  the  Am.  Ophth.  Soc.,  X871,  p.  xa2. 
Z*  Archiv.  C  Ophthal.,  judx.,  3. 


centre  for  vision  which  is  situated  in  the  post  part  of  the 
hemispheres.  When  these  observations  in  man  are  com- 
pared  with  experimental  results  in  animals,  we  may  state 
that  the  visual  centre  is  mainly  in  the  occipital  lobes. 

I  shall  add  but  one  case  to  the  foregoing,  which,  on  ac- 
count of  the  theoretical  and  practical  value,  will  be  given 
somewhat  in  detail.*  A  man  of  forty-five  suffered  in 
March,  1881,  with  severe  headache  in  the  left  occipital  re* 
gion,  and  observed  also  that  he  did  not  see  objects  on  the 
right  of  the  field  of  vision.  A  careful  examination,  in  July^ 
revealed  a  right  hemianopia  nearly  to  the  median  line, 
and  normal  fundi  oculL  At  this  time  there  was  no  other 
cerebral  symptom  of  local  significance,  but  shortly  after- 
ward an  awkwardness  in  the  use  of  the  right  extremities 
was  observed.  There  was  also  observed  impairment  of 
the  cutaneous  sensibility,  muscular  sense  and  muscular 
power  of  the  right  extremities.  At  first  these  were  more 
marked  in  the  leg,  but  they  gradually  increased  in  both 
arm  and  leg,  until  these  functions  became  entirely 
abolished.  August  ist,  slight  paralysis  of  the  muscles 
supplied  by  the  lower  branch  of  the  right  seventh  nerve 
was  observed. 

From  the  above  symptoms  and  the  presence  of  fever, 
emaciation,  etc.,  a  brain  abscess  was  diagnosed,  and, 
August  3d,  the  abscess  was  opened.  The  trephine  was 
applied  at  a  locality  supposed  to  correspond  to  the 
posterior  superior  angle  of  the  left  parietal  bone.  About 
an  ounce  and  a  half  of  pus  escaped  after  an  incision  into 
the  brain.  For  some  days  there  was  improvement,  dim- 
inution of  paralysis,  etc.,  but  patient  died  August  16th. 

Post-mortem  examination  revealed  what  Wernicke  de- 
scribed as  a  tubercular  abscess  of  the  brain.  The  abscess 
was  of  the  size  of  a  large  hen's  egg,  and  occupied  the 
left  occipital  and  parietal  lobes,  occupying  rather  the 
median  than  external  portion  of  the  parietal  lobe. 

The  lesion  here  found  in  itself  might  be  of  no  more  | 
localizing  value  for  the  symptom  hemianopia  than  sev- 
eral of  those  already  mentioned,  merely  indicating  that 
hemianopia  was  dependent  upon  disease  of  a  hemisphere. 
But  taken  in  consideration  with  the  development  of  the 
symptoms  and  other  facts  in  cerebral  localization  the 
case  is  more  significant.  There  was  a  gradual  develop- 
ment of  the  symptoms,  first  hemianopia  and  then  gradual 
involvement  of  the  leg,  arm,  and  face.  Now  the  centres 
for  the  nmscles  of  the  leg,  arm,  and  face  lie  respectively 
more  and  more  distant  from  what  we  have  taken  to  be 
the  centre  for  vision.  So  the  development  of  the  symp- 
toms seem  to  demand  the  following  explanation :  the 
abscess  began  in  the  occipital  lobe,  causing  only  disturb- 
ance of  vision,  and  as  it  extended  forward  it  gradually  1 
involved  the  centres  for  the  leg,  arm,  and  face. 

It  may  be  permitted  to  add  a  word  of  admiration  for 
the  boldness  of  applying  to  practice  the  principles  gained 
from  scientific  study.  Although  operative  interference 
was  without  avail  in  this  case,  it  may,  nevertheless  lead 
to  its  more  successful  issue  in  the  future. 

This  closes  the  pathological  material  at  our  command 
for  the  establishment  of  a  cerebral  centre  of  vision  in 
man.  The  cases  are  few  in  number,  partly  because  those 
instances  are  rare  where  such  circumscribed  lesions  oc- 
cur, partly  because  careful  examinations  during  life  are 
usually  not  made,  have  scarcely  been  made  at  all  until 
recent  years.  More  than  one-half  of  the  above  cases 
were  reported  within  the  last  three  years. 

A  proper  examination  for  the  symptoms  is  more  im- 
portant than  is  usually  believed.  Patients  'very  fre- 
quently do  not  observe  visual  disturbances  when  they 
are  only  partial,  or  they  falsely  interpret  them,  for  in- 
stance, say  that  they  do  not  see  with  the  left  eye,  when 
there  is  left  hemianopia.  Physicians  also  frequently  over- 
look these  symptoms,  and  blunders  have  been  made  by 
skilled  specialists  which  were  only  rectified  by  careful  peri- 
scopic  examinations. 

We  have  now  done  with  the  evidence,  gained  from  the 

>  Wernicke  aod  Hahn  (Virchow*s  Archiv.,  i88a,  xxxvii.,  a). 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


345 


study  of  anatomical,  physiological,  and  pathological  data, 
trhich  bears  on  the  question  of  the  cerebral  centres  of 
vision.  We  have  seen  that  all  points  alike  to  the  pres- 
ence of  such  a  centre  in  the  cortex  of  the  posterior  por- 
tion of  the  hemispheres.  It  may  be  that  other  parts  of 
the  brain  are  in  some  manner  connected  with  the  sense 
of  vision,  for  the  subject  is  not  entirely  cleared  up.  But 
it  mast  be  accepted  as  an  acquired  fact  in  anthropological 
science  that  the  sense  of  vision  is  intimately  connected 
with  a  limited  portion  of  the  cerebral  cortex. 


A  CASEJOF   POISONING   BY  PODOPHYLLUM 
PELTATUM. 

By  WALTER  B.  REYNOLDS,  M.D., 

WASHINGTON,  D.  C,  * 

The  following  case  is  presented  to  the  profession  with 
the  belief  that  it  is  of  sufficiently  rare  occurrence  to 
make  it  of  some  interest  to  them,  as, well  as  being  worthy 
of  record. 

About  I  P.M.,  on  the  9th  of  June  last,  I  was  summoned 

to  come  at  once  to  see  Mrs.  C ,  who  was  said  to 

have  been  taken  suddenly  and  critically  ill.  On  reach- 
ing the  patient  I  found  her  with  the  following  symptoms, 
to  wit :  incessant  retching ;  scant,  but  very  frequent 
bloody  stools ;  violent  colic  and  tenesmus ;  eyes  sensi- 
tive to  light,  and  pupils  slightly  contracted ;  skin  and 
extremities  cold  ;  slight  indications  of  respiratory  paral- 
ysis ;  pulse  rapid  and  weak,  and  other  usual  symptoms  of 
collapse.  She  was  considerably  excited,  but  perfectly  con- 
scious, and  stated  that  she  had  been  feeling  badly  for 
several  weeks  on  account  of  chilly  sensations  and  the 
irregularity  of  her  bowels.  To  remedy  these  troubles 
she  had  taken,  the  evening  before,  three  of  Dr.  Jayne's 
liver  pills,  to  which  she  attributed  her  illness.  She  de- 
nied  having  taken  anything  else,  but  mentioned,  in  reply 
to  a  question,  that  she  had  not  had  her  sickness  for  six 
weeks.  Nor  had  she  suffered  from  any  of  the  early 
symptoms  of  gestation.  Brandy  and  fomentations  were 
the  domestic  remedies  that  had  been  used. 

I  had  her  head  lowered,  applied  external  warmth,  with 
a  large  sinapism  over  her  abdomen,  and  gave  a  hot 
brandy  punch  (which  was  repeated  every  half  hour)  just 
as  soon  as  she  ceased  retching,  which  had  returned 
shortly  after  my  arrival.  The  matter  vomited  consisted 
of  bile  and  glairy  mucus,  each  in  a  small  quantity.  The 
punch  was  retained,  and  together  with  the  external 
warmth  caused,  in  a  short  time,  her  skin  to  become 
somewhat  warmer,  and  she  expressed  herself  as  feeling 
more  comfortable  ;  but  she  still  had  frequent  paroxysms 
of  great  pain.  To  relieve  this  I  endeavored  to  adminis- 
ter a  hypodermic  injection  of  sulphate  of  morphia,  and 
also  brandy,  but  my  syringe  could  not  be  made  to  work. 
As  the  patient  had  been  almost  constantly  vomiting  and 
purging  since  2  a.m.,  neither  an  emetic  nor  cathartic 
were  considered  necessary.  A  messenger  having  re- 
turned from  the  drug  store,  I  placed  on  her  tongue  one 
powder  of  the  following  formula  : 

5.  Bismuth,  subnit 6.00  grm. 

Pulv.  ipecac,  comp 2.00  grm. 

M,  Ft.  chts.  no.  vj. 

Sig. — One  every  half  hour  until  two  have  been  taken, 
and  then  repeat  hourly. 

I  A  warm  starch  enema  was  also  given,  and  repeated 
I  after  an  interval  of  two  hours.  The  patient  was  to  use 
I      a  bed-pan,  and  to  be  kept  as  quiet  as  possible.     After 

remaining  awhile  I  left,  giving  instructions  that  I  should 

be  sent  for  in  case  any  change  occurred,  and  that  I  would 

return  later. 
At  6  P.M.    Mrs,  C was   somewhat   easier.     Her 

bowels  continued  to  move  frequently,  and  were  still  mel- 


aenatic  in  character,  but  did  not  occasion  as  much  pain. 
Her  pulse  was  90,  a  little  stronger,  but  irregular.  Retch- 
ing had  ceased.  She  considered  herself  stronger,  but 
complained  of  difficulty  in  breathing,  and  had  suppression 
of  urine.  The  punch  was  made  stronger  (32  grm.  instead 
of  16  grm.  of  brandy  to  a  tumbler  of  milk),  and  ordered 
to  be  given,  in  the  form  of  milk  punch,  a  tablespoonful 
every  fifteen  or  twenty  minutes  until  the  distress  in 
breathing  had  improved,  as  I  noticed  it  was  not  so  great 
for  awhile  after  tlie  stimulant  had  been  taken.  The 
powders  were  continued  every  two  hours.  Warm  cloths 
were  applied  over  the  hypogastric  region,  and  renewed 
every  two  hours,  with  a  wineglassful  of  flax-seed  tea 
every  three  or  four  hours.  Her  diet  to  consist  of  milk, 
weak  tea,  and  two  soft  boiled  eggs  in  case  she  desired 
anything  to  eat. 

Her  husband  was  present  at  this  visit,  and  I  elicited 
the  following  facts,  which  confirmed  my  suspicion  that 
his  wife  had  taken  an  excessive  dose  of  one  of  the  drastic 
cathartics.  At  the  suggestion  of  a  lady  neighbor  she 
purchased  the  previous  day  two  May-apples  (weighing 
16  grm.),  one  of  which  she  steeped  for  an  hour  in  half  a 
pint  of  boiling  water ;  all  of  which  she  drank  warm,  after 

straining  it,  on  retiring  at  10  p.m.,  the  8th.     Mrs.  C 

is  a  healthy,  tall,  well-developed  German  woman,  about 
twenty-five  years  of  age,  and  the  mother  of  three  living 
children. 

On  the  morning  of  the  loth  she  was  very  much  im- 
proved. However,  she  slept  very  little  during  the  night, 
owing  to  continued  hypercatharsis,  which  had  occurred 
about  every  three  hours  since  my  last  visit.  Her  pulse 
was  85,  and  stronger,  but  still  irreisrular.  She  suffered 
with  comparatively  little  pain,  and  while  it  continued  to 
return  periodically,  yet  the  intervals  were  gradually  being 
lengthened.  Complained  of  general  weakness  and  sore- 
ness, with  a  feeling  throughout  the  digestive  tract  as  if 
she  "  had  swallowed  boiling  water."  She  had  to  discon- 
tinue the  milk  punch,  as  it  produced  retching,  but  took 
instead  brandy  and  water  at  the  hours  ordered.  The 
powders  were  continued  every  three  hours;  also  flax- 
seed tea  every  two  hours.  Warm  applications  were  con- 
stantly kept  over  the  abdomen,  for  their  soothing  effect, 
her  urine  being  passed  in  the  normal  quantity.  The  other 
treatment  was  coi3 tinned,  with  the  exception  of  the 
brandy,  which  was  allowed  only  three  times  daily,  as  no 
difficulty  of  breathing  was  experienced. 

The  following  morning  I  found  that  the  patient  had 
had  a  good  night's  rest,  and  no  movement  of  the  bowels 
nor  pain  since  5  p.m.,  the  previous  day.  Said  she  rel- 
ished her  breakfast,  and  felt  well  enough  to  be  up  if  she 
were  not  so  sore  and  weak.  There  was  no  symptom  of 
salivation  at  any  stage  of  her  case,  as  has  generally  oc- 
curred in  experiments  with  this  medicine,  especially  on 
the  lower  animals.  I  gave  directions  for  her  to  remain 
quietly  in  bed  for  a  few  days ;  to  take  beef-tea  in  addi- 
tion to  her  other  diet,  with  one  powder  twice,  and  brandy 
(16  grm.)  three  times  daily.  Flax-seed  tea  every  three 
or  four  hours. 

Three  days  later  I  called,  and  found  Mrs.  C at- 
tending to  her  household  duties.  She  had  steadily  im- 
proved, and  I  did  not  detect  any  irregularity  in  her  pulse, 
though  it  was  still  weaker  and  faster  than  normal.  She 
looked  pale,  and  said  she  felt  weak,  but  in  all  other 
respects  thought  herself  better  than  she  was  before  tak- 
mg  the  May-apple.  I  cautioned  her  in  regard  to  diet ; 
stopped  the  powders,  but  continued  the  brandy  twice 
daily.     I  ordered  the  following  : 

3.  Tinct.  ferri  chlor 24.00  c.c. 

Quiniae  sulph 4.00  grm. 

Strichniae  sulph 0.03  grm. 

Syr.  aurantii  flor 48.00  c.c. 

Aquae q.  s.  ad.  128.00  c.c. 

M.  Ft.  sol.     Sig. — A  teaspoonful  in  a  tablespoonful 
of  water  morning  and  night,  through  a  quill.  ^ 

No.  152a  Connecticut  Avenub.' 


346 


THE   MEDICAL  RECORD. 


[September  27,  1884. 


HYSTERIA  IN  THE   MALE. 
By  spencer  M.  FREE,  A.M.,  M.D., 

iPmrStCtAN  TO  NOBTHWBSTKRN  MINING  AND  BXCHANGB  COMPANY. 

Having  read  in  several  recent  journals  reports  of  hysteria 
in  the  male  subject,  I  present  my  experience,  hoping  it 
may  be  of  value  in  helping  others  to  avoid  the  errors 
which  I  made. 

My  practice  is  in  a  mining  town  of  about  three  thou- 
sand inhabitants  (including  children),  and  nearly  all  of 
them  are  under  my  care  as  the  company's  physician.  I 
have  hence  seen  many  ca^es  of  this  disease,  but  only  four 
in  the  male  in  my  own  practice,  and  one  in  consultation. 
This  makes  my  proportion  of  cases  one  male  to  about 
fifty  female,  instead  of  one  to  twenty  as  recorded  by 
Briquet. 

I  shall  relate  one  case  in  /«//,  as  it  illustrates  clearly 
the  disease  as  well  as  the  mistakes  of  diagnosis. 

Case   I. — June   20,   1882,  I   was  called   to   see   L. 

T ,  adult,  single,  laborer,  generally  in  the  woods  or 

on  the  farm ;  weight,  one  hundred  and  sixty-five  pounds. 
He  had  always  been  well.  Had  been  suddenly  attacked 
with  diarrhoea  and  slight  vomiting.  Diagnosed,  "summer 
diarrhoea.'*  Treatment  caused  improvement  for  a  few 
days,  when  a  second  attack  occurred.  He  again  improved 
until  June  29th,  when  he  was  **  taken  with  "  headache. 
The  pain  gradually  extended  downward  along  the  spine, 
until  at  the  end  of  five  days  the  whole  vertebral  column 
was  involved.  Pains  were  paroxysmal,  and  at  times  so 
severe  as  to  be  alarmmg.  There  was  much  tenderness 
on  pressure.  The  system  in  general  showed  symptoms 
of  disease,  except  the  temperature,  which  remained  below 
99.2**.  Treatment  availed  very  little.  Occasionally  he 
improved  for  a  few  hours.  Diagnosis  now  made  of  spinal 
irritation  or  meningitis.  This  state  of  things  continued 
until  July  6th,  when  he  was  attacked  with  pains  in  the 
abdomen,  resembling  colic.  He  and  the  family  said  he 
had  high  fever  each  afternoon,  and  that  at  these  times  the 
pains  were  much  worse.  I  took  occasion  to  see  him  at 
such  times^  but  the  thermometer  showed  only  slight  in- 
crease of  temperature.  When  the  abdominal  pains  de- 
veloped those  along  the  spine  subsided  to  a  great  extent, 
though  they  did  not  disappear.  I  became  worried.  I 
had  twice  made  a  wrong  diagnosis.  While  thinking  over 
the  case  it  flashed  into  my  mind,  "Could  it  be  hysteria  ?  " 
I  traced  the  family  history  for  two  generations,  but  noth- 
ing of  value  was  found,  except  that  some  of  his  mother's 
family  were  "nervous"  (^to  use  her  words).  On  the  night 
of  July  8th  I  was  called  m  haste,  as  he  was  **  dying."  I 
found  him  apparently  with  severe  colic.  I  applied  hot 
fomentations,  gave  hypodermic  injections  of  morphia, 
and  carefully  watched  for  hysteric  symptoms.  I  gave 
him  two  and  one-third  grains  of  morphia  in  this  way  and 
a  small  amount  of  chloroform  by  inhalation  ere  he  slept. 
(I  have  noted  several  times  the  large  amount  of  morphia 
that  hysterical  patients  will  tolerate  without  producing 
sleep.)  I  noticed  that  he  inquired  for  a  young  lady  of 
the  house,  and  was  restless  when  she  was  out  of  the 
room ;  that  he  would  not  allow  me  to  leave  the  bedside ; 
and  that  he  manifested  a  few  other  symptoms  of  an 
hysterical  nature.  I  learned  that  he  had  proposed  mar- 
riage to  this  young  lady  and  had  been  refused.  I  de- 
termined, in  view  of  all  this,  to  treat  for  hysteria,  and  the 
next  morning  I  gave  him  a  remedy  which  is  a  favorite 
with  me  in  this  feigning  (sham)  variety,  namely,  a  "  blow- 
ing up."  I  began  severely  by  telling  him  that  nothing 
was  the  matter,  that  he  should  be  ashamed  of  himself, 
that  he  should  get  up  and  go  to  work  and  relieve  the 
family  of  this  annoyance  and  expense,  etc. 

Of  course  he  pleaded  and  tried  to  arouse  my  sympathy. 
I  gaare  none  ;  he  then  tried  abusing  me  and  berating  my 
knowledge,  I  did  not  become  angry,  but  continued  my 
severity.  Finally  he  began  to  swear,  he  sprang  up  in 
bed,  clenched  his  fists,  and  prepared  to  "  lick  "  me  and 
put  me  out  of  the  house.  I  did  not  flinch  but  looked 
him  steadily  and  firmly  in  the  eye.    Suddenly  he  dropped 


"  in  a  heap "  upon  the  bed,  was  powerless,  and  cried 
and  sobbed.  I  had  conquered.  After  giving  a  few  in- 
structions as  to  his  management  I  left 

He  got  out  of  his  bed  in  a  few  hours  (a  thing  which 
he  had  not  done  before  for  nearly  three  weeks).  In  two 
days  he  went  to  work,  and  has  lost  no  time  on  account  of 
sickness  up  to  this  date.  I  consider  this  a  pure,  un- 
adulterated case  of  hysteria,  and  the  only  discoverable 
cause  disappointment  in  love. 

The  plan  of  treatment  here  used  would  not  be  ap- 
propriate were  the  physician  dependent  upon  patronage 
for  his  practice  and  living,  as  he  would  not  be  called 
upon  again  by  the  patient,  and  possibly  not  by  the  fam- 
ily. The  ant  et  potass,  tartrate  would  probably  be  as 
effective,  and  not  productive  of  harm  to  the  one  pre- 
scribing it. 

Case   II. — E.    L ,   adult,  laborer.     While  intox- 

icated  he  fell  into  a  chaldron  of  boiling  oil.  After  ano- 
dynes had  been  dispensed  with  he  became  wakeful,  and 
soporifics  had  little  effect.  I  noticed  that  he  fancied  the 
thermometer,  and  following  the  suggestion  I  impressed 
him  with  its  wonderful  power.  He  said  he  could  feel  its 
influence  through  the  entire  body.  In  from  two  to  three 
minutes  after  placing  it  in  the  mouth,  he  would  be  asleep 
and  remain  so  for  several  hours.  I  used  it  in  this  way 
twice  a  day  until  his  death,  twelve  days  after  the  acci- 
dent, from  perforation  of  the  duodenum. 

Case  III. — Consultation.  Adult,  woodsman.  He  had 
bronchitis,  but  was  nearlv  well,  when  he  suddenly  "  lost 
his  voice."  This  condition  had  lasted  five  days  when  I 
saw  him.  I  told  him  the  doctor  would  get  him  an  in« 
strument,  explained  its  effect,  etc.  He  returned  at  the 
appointed  time  still  speechless.  The  doctor  placed  the 
thermometer  under  his  tongue,  and  had  the  pleasure  of 
seeing  him  perfectly  cured  by  one  application.  The  dis- 
ease had  not  returned  when  I  heard  from  him  more  than 
two  years  afterward. 

Cases  IV.  and  V.  are  miners,  adults,  unmarried. 
In  Case  IV.  the  hysteria  took  the  form  of  "  irritable  blad- 
der." Case  V.  "felt  funny  all  over,"  nor  could  we  evei 
obtain  a  better  description  of  his  ailments.  Both  were 
cured  (not  perfectly,  but  satisfactorily)  with  placebo 
treathient.  These  cases  are  interesting,  chiefly  as  illus- 
trating the  cause.  The  patients  both  masturbated  to  a 
small  extent,  and  will  probably  be  permanently  cured  by 
marriage. 

After  carefully  studying  the  cause  in  all  my  cases, 
male  and  female,  I  find  that  in  the  great  majority  of 
them  it  is  some  disturbance  of  the  sexual  system  or  or- 
gans. This  is  nearly  always  true  in  the  feigned  variety 
of  cases. 

Dagus  Minbi,  Elk  County,  Pa.  ; 


Rectal  Etherization. — Dr.  W.  H.  Taylor,  of  New 
Bedford,  Mass.,  sends  us  the  following :  "  Apropos  of  rectal 
etherization,  I  beg  leave  to  submit  the  following  case : 
On  July  30,  1884,  at  10  A.M.,  I  made  an  attempt  to  close 
a  wound  of  the  larynx  which  had  been  produced  with 
suicidal  intent  on  May  15,  1884.  Anaesthesia  was  at 
first  induced  by  ether  applied  on  a  sponge  over  the 
wound.  When  full  insensibility  occurred,  ether  vapor 
was  conducted  into  the  previously  washed  rectum  from  a 
bottle  in  a  water-bath  at  140**  F.,  supplied  with  a  rubber 
tube  eight  feet  in  length.  About  four  ounces  pf  Squibb's 
stronger  ether  were  given  by  rectum,  and  all  entered  ex- 
cept a  few  drops  which  had  condensed  in  the  rubber  tube' 
The  apparatus  was  in  charge  of  my  friend;  G.  De  N. 
Hough,  M.D.,  one  of  the  internes  of  Bellevue  Hospital 
Notwithstanding  the  free  entrance  of  the  vapor,  the  pa- 
tient manifested  evidences  of  pain  during  the  operation, 
and  stated  subsequently  that  he  was  conscious  during  a 
large  part  of  the  time.  He  sat  up  on  the  afternoon  of 
the  same  day,  and  partook  of  the  evening  meal  as  usual. 
No  trouble  was  experienced  at  any  time  from  the  ether, 
except  the  failure  to  induce  anaesthesia,  "j 


September  27,  i884,] 


THE  MEDICAL  RECORD. 


347 


Cardiopathy  of  the  Menopause. — Under  this  title 
Dr.  £.  Client  writes,  in  the  Zyon  Midical  of  August 
3  and  10,  1884,  concerning  a  peculiar  functional  dis- 
order of  which  he  has  had  occasion  to  observe  several 
examples.  The  patients  presented  all  the  symptoms  of  a 
profound  disturbance  of  the  cardiac  functions  without 
any  physicial  signs  of  valvular  lesion.  The  age  at  which 
the  first  symptoms  appeared  was  from  forty-six  to  fifty 
years.  The  patients  presented  nothing  striking  in  their 
personal  or  hereditary  history.  They  were  all  well  built, 
healthy  women,  accustomed  to  manual  or  household 
labor,  but  never  exposed  to  excessive  fatigue  such  as 
might  occasion  cardiac  hypertrophy.  Some  had  borne 
children,  others  had  never  been  pregnant.  There  was 
no  hysterical  element  in  the  cases,  nor  had  any  of  them 
suffered  from  rheumatism.  The  first  symptoms  appeared 
before  the  menses  had  ceased  entirely,  but  when  they 
bad  become  irregular  either  in  their  time  of  recurrence 
or  in  the  amount  of  the  flow.  The  onset  was  gradual. 
During  an  indeterminate  period,  for  perhaps  two  or  three 
months,  the  women  suffered  from  an  indefinite  feeling  of 
malaise,  their  strength  diminished  and  they  were  less 
able  to  resist  fatigue,  and  finally  they  began  to  suffer 
from  palpitation.  The  evolution  of  the  £sease,  while 
progressive,  is  yet  interrupted  by  intervals,  more  or  less 
extended,  of  apparent  health,  but  each  recurring  attack 
is  more  severe  than  the  preceding  one.  The  palpitations 
are  soon  followed  by  dyspnoea  on  exertion,  although 
there  is  not  the  slightest  difficulty  of  breathing  when  at 
rest  Sleep,  however,  is  often  broken  by  distress  in  the 
region  of  the  heart.  After  a  time  all  these  symptoms 
become  very  niarked  upon  the  slightest  movement,  and 
are  only  alleviated  somewhat  when  the  patient  sits  per- 
fectly still  in  the  chair.  Another  phenomenon  is  a  feel- 
ing of  faintness,  which  goes  on  sometimes  to  actual 
syncope.  The  examination  of  the  heart  gives  a  negative 
result.  The  cardiac  impulse  is  a  little  exaggerated,  the 
rhythm  may  be  irregular,  but  the  valvular  sounds  are 
distinct  and  without  the  faintest  murmur,  the  first  sound 
being  somewhat  the  weaker.  There  is,  however,  an  ex- 
treme rapidity  of  the  heart's  action,  the  pulse-rate  being 
often  150  to  160  to  the  minute.  At  first  there  is  no 
cedema,  but  after  three  or  four  attacks  there  may  be  a 
slight  swelling  about  the  malleoli  or  in  the  integument 
over  the  hypogastric  region.  Whatever  may  be  the  in- 
tensity of  the  cardiac  symptoms,  there  are  no  bronchial 
nor  pulmonary  disturbances.  The  dyspnoea  is  entirely 
of  cardiac  origin.  There  is  never  any  venous  stasis,  but 
there  is  an  evident  spasm  of  the  arterioles.  There  is  a 
remarkable  pallor  of  the  face,  which  is  due,  the  author 
believes,  to  this  vascular  spasm  rather  than  to  anaemia. 
The  urine  is  in  general  abundant  enough,  except  at  the 
height  of  an  attack,  when  its  excretion  may  be  nearly 
suppressed  ;  it  never  contains  any  albumen.  The  course 
of  the  affection  is  peculiar,  occurring  as  it  does  in  par- 
oxysms separated  by  intervals  of  varying  duration.  As 
the  disease  advances  the  intervals  of  remission  grow 
shorter.  The  attacks  last  usually  about  a  week,  but 
might  be  of  longer  duration  were  *  it  not  for  medical  in- 
tervention. The  affection  continues  for  an  indefinite 
period,  but  the  prognosis  is  favorable  despite  the  ap- 
parently grave  symptoms  of  dyspnoea,  oedema,  weak- 
ness, etc.  The  -disease  subsides  as  it  began,  the  inter- 
vals of  health  growing  longer  and  the  paroxysms  shorter 
and  of  less  intensity.  The  cause,  the  author  thinks,  is  to 
be  found  in  a  modification  of  innervation  by  the  great 
sympathetic,  and  especially  in  excitation  of  the  cardiac 
nerves.  The  treatment  is  by  means  of  large  doses  of 
infiision  of  digitalis,  beginning  with  an  infusion  of  eight 
gndns  of  the  powdered  leaves,  and  reducing  gradually  to 
five  grains.  Sometimes  the  patients  acquire  a  disgust 
for  this  drug,  and  then  Dr.  Clement  substitutes  the  alco- 
holic extract  of  convallaria  maialis  in  the  dose  of  fifteen 


to  twenty  grains.  But  the  results  are  much  less  satis- 
factory than  when  digitalis  is  employed.  The  paroxysms 
of  dyspnoea  are  best  relieved  by  the  preparations  of  opium, 
more  especially  morphine.  At  the  same  time,  of  course, 
the  patients  should  remain  as  quiet  as  possible  and  avoid 
anything  that  may  cause  mental  or  physical  disturbance. 

Malarial  Orchitis. — Dr.  Angelo  Zacco  relates  in 
the  Gazetta  degli  Ospiiali,  Nos.  16  and  18,  1884,  the 
case  of  a  man  who  applied  for  relief  on  account  of  or- 
chitis. The  right  testicle  was  swollen  to  three  times  its 
normal  size  and  was  painful  to  the  touch.  There  was 
also  a  slight  amount  of  epididymitis.  The  patient  had 
received  no  injury  and  had  never  had  syphilis,  gonor- 
rhoea, nor  mumps.  All  the  ordinary  remedies  were  tried 
without  effect,  and  as  the  patient  was  suffering  from  a 
mild  form  of  intermittent  fever  he  was  given  quinine. 
Under  this  treatment  the  swelling  of  the  testicle  rapidly 
subsided.  The  author  believed  that  the  orchitis  was 
caused  by  direct  action  of  the  njalarial  microbe  carried 
to  the  testicle  in  the  blood  stream. 

Treatment  of  Sciatica  by  Congelation. — Actirg 
upon  the  theory  that  blisters  and  other  revulsive  meas- 
ures exert  their  therapeutic  effects  in  sciatica  through 
the  nerve  terminations,  M.  Debore  thought  to  act  upon 
a  greater  extent  of  surface  and  obtain  a  correspondingly 
greater  benefit  by  congealing  the  integument.  This  he 
did  in  a  number  of  cases  by  a  spray  of  chloride  of  methyl, 
and  says  that  the  effect  was  marvellous.  The  relief  to 
the  pain  was  instantaneous,  though  there  were  some- 
times slight  relapses,  which  yielded  at  once,  however,  to 
a  repetition  of  the  congelation.  The  spray  was  directed 
wherever  the  patient  experienced  any  pain,  sometimes 
over  quite  an  extensive  surface.  The  skin  was  blanched 
temporarily  and  occasionally  vesication  was  produced, 
but  ho  other  accidents  occurred.  The  patients  were  all 
men  and  free  from  any  suspicion  of  hysteria. — Revue 
MidicaUy  August  16,  1884. 

Myasis. — Under  this  title  Dr.  Posada-Arango  de- 
scribes, in  the  Journal  de  Medecine  de  Paris  of  Augjust 
16,  1884,  an  affection  caused  by  the  deposition  of  fiies' 
eggs  in  the  nasal  fossae.  He  relates  a  case  occurring  in 
a  farmer*s  boy  fifteen  years  of  age.  The  patient  was  an- 
noyed one  morning  by  a  fiy  getting  into  his  nostril,  but 
it  soon  emerged  and  no  more  was  thought  of  it.  Forty- 
eight  hours  later  he  began  to  have  pain  in  the  nose,  ac- 
companied by  a  slight  bloody  discharge,  and  soon  he 
noticed  a  worm  coming  from  the  nostril.  He  com- 
plained of  severe  headache  and  a  noise  within  the  head 
like  the  rumbling  of  carts  over  a  stony  road.  Dr.  Aran- 
go  removed  as  many  of  the  worms  as  he  could  by 
means  of  a  curette,  and  then  injected  a  decoction  of  an 
aromatic  plant  called  cordoncillo  (a  sort  of  pepper  plant), 
and  blew  tobacco  fumes  into  the  nostril.  By  means  of 
these  applications,  frequently  repeated,  the  nostrils  were 
finally  cleared  of  about  one  hundred  and  twenty  worms. 
Of  the  fourteen  cases  of  this  affection  hitherto  reported, 
nine  ended  fatally.  The  fly  which  deposits  the  eggs  is 
a  little  larger  than  the  ordinary  house-fly,  and  is  of  a 
general  bluish  color,  though  presenting  a  green  or  violet 
metallic  hue  when  seen  in  certain  lights.  The  worms 
are  white,  pointed  at  the  buccal  and  truncated  at  the 
caudal  extremity. 

Acute  Mania  at  the  Menstrual  Period. — Dr. 
Cabad6  relates  the  case  of  a  woman  who,  while  menstru- 
ating, lost  her  husband  under  very  terrifying  circum- 
stances. Menstruation  ceased  at  once  and  did  not  return 
for  eight  months,  during  which  time  the  patient  was  ex- 
ceedingly nervous  and  suffered  from  slight  convulsive 
attacks.  Later  she  had  acute  maniacal  attacks  at  each 
menstrual  period,  being  perfectly  sane  in  the  intervals. 
The  mania  recurred  at  each  monthly  period,  and  was 
only  controlled  by  large  continued  doses  of  bromide  of 
potassium. —  Wiener  Medizinische  Wochenschrift,  No- 
vember 29,  1884. 


348 


THEu<MEDICAL  RECORD. 


[September  27,  1881 


The  Medical  Record 


A  Weekly  yournal  of  Medicine  and  Surgery, 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Ufayette  Place. 

New  York,  September  27,  1884. 

MEDICAL  MANNERS— ANCIENT  AND  MOD- 
ERN. 
A  WRITER  in  an  English  exchange  laments  the  decadence 
of  polite  learning  and  punctilious  manners  among  the 
medical  men  of  to-day.  Once  they  were  y^xy  proficient 
classical  scholars.  Now,  alas,  a  little  dog  Latin,  quantum 
sufficit  for  prescription  writing,  is  all  that  most  of  our 
modern  luminaries  possess.  ♦*  Then,"  he  continues,  **  if 
you  meet  some  of  our  very  old  practitioners  and  contrast 
their  manners  with  the  shining  lights  of  to  day  the  differ- 
ence will  be  perceived.  The  gracious  demeanor,  the 
courtly  address,  the  punctilious  observance  of  courtesy, 
the  accuracy  of  phraseology,  the  general  tone  expressed 
in  the  word  gentleman,  are  remarkable  for  their  absence 
in  the  leading  medical  men  of  to-day.  Brusqueness, 
dogmatism,  self-sufficiency,  brevity  have  taken  their 
place.  Science  is  accountable  for  this.  Only  half  edu- 
cation could  produce  such  men.  Science  contracts — 
limits  the  range  of  reading.  It  confines  the  imagination 
by  which  the  soul  grows.  The  old  classical  education 
enlarged  the  bounds  of  reading  and  of  interest.  In  the 
old  classical  writers  we  find  the  almost  perfection  of 
language,  and  I  might  even  say  of  morality." 

It  may  be  admitted  that  there  is  some  truth  in  the 
criticism  thus  quoted.  Nevertheless  we  are  quite  sure 
that  so  far  as  the  "minor  morals  and  manners  "  are  con- 
cerned, a  comparison  of  those  of  to-day  with  those  of  the 
last  century  will  show  a  vast  advantage  to  the  former. 
In  all  ages  there  have  been  charges  that  virtue  was  de- 
clining. Said  some  one  to  Dr.  Akenside :  **  Doctor,  after 
all  you  have  said,  my  opinion  of  the  profession  is  this :  The 
ancients  endeavored  to  make  it  a  science,  and  failed ;  the 
moderns,  to  make  it  a  trade,  and  succeeded."  This  was 
in  1759,  and  at  the  present  day  we  hear  the  same  melan- 
choly accusation. 

It  may  be  admitted  that  a  hundred  years  ago  there 
was  more  ceremonious  politeness  and  a  greater  stress 
laid  upon  conventional  forms  in  social  and  professional 
intercourse.  But  he  who  reads  the  history  of  those  days 
will  be  convinced  that  beneath  the  polished  exterior  there 
was  far  more  dislike,  envy,  and  bad  feeling  than  exist 
to-day. 

John  Hunter  died  from  a  quarrel  with  his  hospital  col- 
leagues. In  the  eighteenth  century  all  medical  Europe 
rang  with  the  quarrels  between  CuUen  and  Brown  and 
their  respective  adherents.  In  the  time  of  Garth  a  furi- 
ous war  raged  between  the  supporters  and  opposers  of 


the  dispensary  system.    That  was  the  age  of  scribblers, 
and  prominent  physicians  were  constantly  being  lam. 
pooned  by  their  less  known  enemies. 
Says  Dr.  Wynter  to  Dr.  Cheyne  : 

"  Eat  grass,  reduce  thyself  and  die, 
Thy  patients  then  may  live." 

And  some  punctilious  friend  wrote  of  Sir  Richard 
Blackmore,  schoolmaster  and  physician  : 

"  In  vain  his  drugs,  as  well  as  birch  he  tried, 
His  boys  grew  blockheads,  and  his  patients  died." 

Dr.  Armstrong,  author  of  the  "  Art  of  Health,"  con- 
fessed that  he  never  attained  a  large  practice  because 
**  I  could  not  tell  a  heap  of  lies  in  my  own  praise,  nor 
intrigue  with  nurses,  nor  associate,  much  less  assimilate, 
with  the  various  kinds  of  pert,  insipid,  lively,  stupid, 
well-bred,  impertinent,  good-humored,  malicious,  oblig- 
ing,  deceitful,  drivelling  gossips ;  nor  enter  into  juntot 
with  people  I  did  not  like." 

A  great  part  of  the  courtly,  not  to  say  obsequions, 
manners  of  the  last-century  physician  was  assumed  as  a 
feature  in  his  business. 

"If  you  would  be  esteemed  very  wise,  sober,  and 
grave,"  writes  Mead  to  a  young  physician,  "  you  should 
then  learn  most  obsequiously  to  fawn  and  soothe  man, 
woman,  and  child,  since  few  else  will  thrive  well." 

It  would  be  quite  easy  to  cite  many  more  illustrations 
in  evidence  that  there  is  now  more  mutual  good  feeling 
and  kindness,  and  less  coarseness  and  vulgarity  among 
physicians  than  there  ever  has  been.  The  tendency  to 
excessive  specialism,  at  the  expense  of  general  knowl- 
edge and  culture,  must  be  admitted,  and  scientific  study 
does  not  tend  emollire  mores. 

It  would  be  an  interesting  task  to  trace  this  gradual 
decline  of  learning,  in  its  broadest  sense,  among  eminent 
physicians  of  the  past.  Of  the  Elizabethan  physicians 
Lord  Bacon  says  :  "  For  you  shall  have  of  them  anti- 
quaries, poets,  statesmen,  humorists,  merchants,  divines  '^ 
— everything  in  fact  except  skilful  practitioners. 

Later  Sir  William  Temple  paid  a  similar  tribute  to  the 
Faculty,  which  Dr.  Johnson  still  later  accepts  with  some 
hesitation,  **  Whether  what  Temple  says  be  true,  that 
physicians  have  had  more  learning  than  the  other  facul- 
ties I  will  not  stay  to  inquire ;  but  I  believe  every  man 
has  found  in  physicians  great  liberality  and  dignity  of 
sentiment,  very  prompt  eflfusion  of  benevolence,  and 
willingness  to  exert  a  lucrative  art  where  there  is  no 
hope  of  lucre." 

Of  the  modern  physician  it  cannot  be  said  that  he  is 
a  man  of  wide  learning.  He  seeks  rather  to  accumulate 
scientific  knowledge  and  technical  skill.  Whether  a  re- 
action toward  a  more  general  culture,  at  least  as  a  basis 
for  his  education,  might  not  be  a  greater  help  in  the 
practice  of  his  art,  is  a  burning  question  just  now. 


THE   IMPORTANCE    OF    HOLIDAY    SEASONS    FOR  PHY- 
SICIANS. 

When  Addison  tells  us  in  the  "  Spectator  "  that  "  the  pre- 
servation of  life  should  be  only  a  secondary  concern,  and 
the  direction  of  it  the  principal,"  *  he  says  what  is  very 
true,  for  a  well-directed  life  insures  a  healthful  life.  While, 
therefore,  the  higher  aim  is  to  be  approved,  and  undue 

1  Spectator^  No.  35. 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


349 


solidtude  about  the  health  should  be  condemned,  it  is 
onderstood  that  when  to  every  man  in  the  performance 
of  his  daily  duties  work  becomes  irksome  and  painful, 
respite  is  imperatively  demanded,  he  cannot  longer  per- 
sist in  his  tasks  without  physical  detriment 

It  cannot  be  too  much  kept  in  mind  that  labor  is 
physiological  only  when  it  is  agreeable,  and  that  every 
hour  spent  in  goading  a  tired  organism  to  toil,  may 
have  a  pathological  outcome.  When  study  is  attended 
with  that  sense  of  bien  itrt  which  indicates  that  the  brain 
is  abreast  of  its  tasks,  then  and  only  then  is  it  profitable ; 
all  experience  will  attest  this.  When  the  physician  can 
go  through  his  regular  routine  of  daily  calls  with  interest, 
even  with  zest,  and  a  flow  of  spirits,  he  is  working  to  ad- 
vantage ;  when  interest  flags  and  the  spirits  droop,  and 
there  is  organic  discomfort,  it  is  time  for  him  to  have  a  sea- 
son of  rest ;  all  this  is  so  plain  as  to  need  only  to  be  stated. 

Now  that  the  holiday  season  is  well-nigh  over,  and 
business  men  are  returning  to  their  offices  and  clergymen 
to  their  pulpits,  it  is  well  that  that  model  of  perseverance 
and  devotion  to  a  good  calling,  the  city  physician,  who 
has  been  sweltering  at  home  during  the  hot  season,  should 
ask  himself  whether  he  can  afford  not  to  take  suitable 
holiday  enjoyments  ? 

The  question  hardly  deserves  discussion,  for  every 
medical  man  will  be  ready  to  give  the  proper  answer  in 
its  application  to  everybody  but  himself.  He  knows 
that  it  is  a  law  of  nature  that  physicians,  as  well  as  other 
men,  should  have  periodical  seasons  of  rest,  relaxation, 
and  recreation.  He  is  ready  to  urge  upon  his  patients 
the  importance  of  their  availing  themselves  of  the  hy- 
gienic benefits  of  frequent  change  of  scene.  He  tells  the 
active  man  of  business,  the  public  officer,  the  banker,  the 
merchant  whose  liver  and  whose  kidneys  are  becoming 
sluggish,  whose  brain  will  not  work  well,  to  get  out  of 
the  old  ruts,  and  he  orders  the  dyspeptic  clergyman  from 
his  pulpit  to  the  prairies,  the  forest,  or  ocean.  As  for 
himself,  however,  while  others  go  to  the  seaside  he  stays  at 
home ;  the  peculiar  nature  of  his  profession  forbids  that 
he  should  absent  himself  from  his  office  longer  than  a  day 
or  two.  The  clergyman's  salary  goes  on  as  usual  while 
he  is  away,  and  the  manufacturer  may  direct  his  business 
by  telegraph  or  by  letter,  but  the  physician  sees  the  per- 
spective of  his  vacation  pleasures  marred  by  a  dark  back- 
ground of  lost  fees  and  estranged  patrons;  in  short, 
pecuniarily  he  cannot  afford  the  recreation  he  needs. 
We  are  speaking,  of  course,  of  the  great  body  of  strug- 
gling practitioners,  who  have  every  interest  in  keeping 
what  practice  they  have  and  in  adding  thereto— not  of 
those  fortunate  ones  who  were  born  with  silver  spoons  in 
their  mouths.  There  is,  moreover,  an  important  distinc- 
tion to  be  made  in  this  respect  between  city  and  country 
practitioners.  The  city  physician  is  subjected  to  causes 
of  ill-health  from  which  his  country  confrere  is  compara- 
tively exempt.  The  latter  habitually  breathes  purer  air ; 
has  invigorating  rides  over  hill  and  plain  where  nature  in 
her  grandeur  and  loveliness  breaks  in  on  the  monotony 
of  his  toil ;  if  he  has  but  a  few  patients,  these  scattered 
over  a  wide  area  occupy  the  larger  part  of  his  time,  giv- 
ing him  his  fees  and  mileage ;  he  has  some  gardening, 
and  perhaps  some  farming,  which  distract  his  mind  from 
the  cares  of  his  profession,  if  they  do  not  add  much  to 
his  income ;   his  taxes  are  less  than  those  of  his  city 


brother,  and  it  costs  him  in  every  way  less  to  live.  He 
has  fewer  eager  competitors,  and  has  far  less  reason  for 
harassing  anxiety  than  his  metropolitan  friend.  If  the 
latter  has  social  and  aesthetic  and  professional  advan- 
tages of  a  higher  order,  and  more  leisure  for  study  and 
research,  his  manner  of  life  is  more  sedentary  and  conse- 
quently less  invigorating,  and  he  labors  under  the  disad- 
vantage of  not  being  able  to  live  easily  on  a  thousand  a 
year ;  he  has  a  multiplicity  of  cares  and  wants  that  are  pe- 
culiar to  his  condition ;  he  feels  constantly  the  pressure  of 
fierce  competition,  and  unless  possessed  of  rare  equipoise 
of  temper  and  a  philosophic  mind  he  will  be  given  to 
worry,  and  this,  whether  his  practice  be  considerable,  or 
whether  it  be  little.  Statistics  have  shown  that  out  of 
equal  numbers  of  city  and  country  practitioners  the  bal- 
ance of  longevity  is  in  favor  of  the  latter,  who  seem,  as 
we  have  indicated,  to  be  especially  favored  in  the  benev- 
olent economy  of  nature.  It  is  apparent  then,  that  reg- 
ular holiday  seasons  must  be  of  great  hygenic  benefit  to 
every  hard-worked  medical  man,  and  especially  to  the 
harassed  practitioner  of  the  town,  to  whom  it  is,  indeed, 
a  physiological  necessity. 

Some  time  since  we  had  a  brief  conversation  with  a 
medical  gentleman  of  repute  in  a  neighboring  city,  who 
acknowledged  that  he  had  not  for  ten  years  had  a  vaca- 
tion of  even  one  week !  The  experiment,  he  affirmed, 
would  have  been  too  perilous !  He  felt  that  he  must  be 
at  his  post  day  and  night.  He  had  a  large  family  to 
support,  and  he  had  no  practice  to  lose.  He  never 
needed  money  more,  and  cessation  from  work  would  be 
ruin  I  On  questioning  this  individual  we  ascertained 
that  life  was  to  him  a  constant  worry,  and  work  was 
pain.  Appetite  and  digestion  were  failing,  and  he  no 
longer  slept  well  He  had  become  *'  disgusted  with  his 
practice  and  with  his  patients,''  and  it  was  with  difficulty 
"  that  he  could  treat  them  with  any  sympathy  and  pa- 
tience.*' '*  I  hate  those  old  cases,  and  those  old  faces/' 
he  said,  "collecting  has  become  irksome,  and  the  sight 
of  an  unpaid  bill  makes  me  desperate."  Some  vehement 
expostulation  on  our  part,  and  urging  of  our  friend  to 
break  away  from  his  work  at  whatever  risk  and  cost  finan- 
cially, was  certainly  of  no  avail ;  and  we  have  within  a 
few  days  seen  in  a  local  paper  the  notice  of  his  death, 
"from  mental  alienation  and  softening  of  the  brain." 

We  do  not  doubt  that  there  are  many  in  the  profession 
to-day  who  are  the  subjects  of  experiences  similar  to 
those  above  depicted,  and  who  have  the  same  appeals 
from  the  depths  of  the  unconscious  life;  appeals  and 
warnings  which  cannot  safely  be  disregarded.  It  will 
not  do  to  trifle  with  these  imperious  feelings  of  the  or- 
ganic nature,  indicative  of  discomfort,  maladjustment, 
and  uncompensated  waste  in  the  highest  centres  of  in- 
nervation. The  part  of  true  economy,  as  well  as  the 
part  of  duty,  is  always  to  seek  suitable  relaxation  and  rest. 


THE  PROGRESS  OF  THE  COLLECTIVE  INVESTIGATION 
MOVEMENT. 

As  the  result  of  considerable  previous  work  on  the  part  of 
GuU,  Paget,  Clark,  Lister,  and  other  English  physicians, 
an  International  Committee  on  Collective  Investigation 
was  organized  at  the  meeting  of  the  Medical  Congress 
in  Copenhagen.  This  Committee,  after  two  meetings, 
arranged  for  the  nomination  of  the  following  Working 


350 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


Committee  at  the  close  of  Sir  William  GulVs  address : 
For  England,  Gull,  Humphry,  and  Mahomed;  for  India, 
Fayrer ;  for  Denmark,  Trier  and  Lange ;  for  Scandinavia, 
Bull ;  for  Russia,  Rauchfuss ;  for  Switzerland,  Despine  ; 
for  Germany,  Ewald  and  Bernhardt ;  for  Austria,  Schnitz- 
ler  and  Pribram  ;  for  France,  Bouchard  and  Lupine ;  for 
the  United  States  of  America,  Jacobi  and  Davies ;  for 
South  America,  Gutierrez  Ponce.  Professor  Koranyi 
was  subsequently  added  as  representative  of  the  kingdom 
of  Hungary. 

The  above  Committee  immediately  met  and  organized. 
Its  first  work  was  to  appoint  an  Executive  or  Sub-Com- 
mittee, which  was  done  in  the  following  resolutions  : 

1.  That  the  Secretary  be  instructed  to  prepare  a  state- 
ment as  to  the  objects  of  the  Committee,  for  translation 
and  publication  in  the  journals  of  the  various  countries 
represented. 

2.  That  a  Sub-Committee  be  appointed. 

3.  That  for  the  present  it  consist  of  not  more  than 
three  members. 

4.  That  the  three  members  be  Professor  Humphry, 
Dr.  Mahomed,  and  Dr.  Isambard  Owen. 

5.  That  the  Sub-Committee  be  directed  in  the  first 
instance  to  prepare  a  list  of  subjects  suitable  for  investi- 
gation by  the  Committee,  and  to  submit  the  list  to  the 
members  of  the  Committee  for  choice ;  further,  upon  such 
choice  being  made,  to  prepare  memoranda  and  questions 
upon  the  subjects  chosen,  and  submit  them  to  the  mem- 
bers of  the  Committee  in  like  manner ;  and  that,  upon 
the  acceptance  of  the  memoranda  and  questions  by  the 
members  of  the  Committee,  the  representatives  of  each 
nation  be  left  to  obtain  the  information  required,  inde- 
pendently, in  such  manner  as  they  may  prefer. 

6.  That  each  member  of  the  Committee  be  requested? 
on  returning  home,  to  write  his  views  on  the  subject  of 
the  proposed  investigation  to  the  Sub-Committee,  who 
will  communicate  again  with  the  members. 

Thus  the  work  stands  for  the  present. 

It  is  getting  to  be  more  and  more  felt  by  the  medical 
world  that  collective  investigation  is  to  be  a  power- 
ful agent  in  medical  progress.  But  it  is  still  more  surely 
seen  that  it  is  an  agent  which  has  to  be  managed  very 
carefully.  There  are  only  certain  lines  of  medical  inquiry 
along  which  it  will  as  yet  serve  any  good  purpose.  And 
eventually  it  will  be  found  that  to  get  trustworthy  results 
collective  investigation  must  be  confined  to  professional 
men  of  known  character  and  capacity,  in  other  words, 
collective  investigation  must  be  limited  to  experts. 


FURTHER  CONTRIBUTIONS  TO  THE  CHOLERA  GERM 
QUESTION. 

Dr.  H.  Van  Dyke  Carter,  of  Bombay,  in  The  Lancet  iox 
-September  6th,  describes  the  results  of  his  investigations 
of  cholera  stools.  He  has  discovered  an  organism  which 
he  figures,  and  which  certainly  resembles  very  much  the 
comma-bacillus  of  Koch.  As  Dr.  Carter  represents  it, 
however,  it  is  longer  and  has  more  of  the  spiral  curves, 
being  unmistakably,  if  the  drawings  are  correct,  a  spiril- 
lum. This  organism  was  not  found  in  every  case  of 
cholera  examined,  while  it  was  found,  though  rarely,  in 
the  stools  in  dysenteric  and  diarrhoeal  cases.  Its  real 
character  was  not  tested  by  cultivation,  however,  so  that 


Dr.  Carter's  observations  have  in  themselves  but  little 
value. 

From  Marseilles  come  reports  of  a  different  nature 
regarding  the  cholera  organism.  Drs.  S.  Maurin  and 
Lange,  who  have  been  working  in  that  city  since  the 
departure  of  Koch,  announce  that  they  have  found  a 
mucor  which  they  believe  to  be  the  actual  agent  in  the 
propagation  of  cholera.  This  mucor  is  really  only  the 
mature  form  of  the  comma-bacillus,  out  of  which  it  de- 
velops. 

It  appears,  according  to  an  account  given  in  the  Brit" 
ish  Medical  Journal^  on  the  fourth  or  fifth  day,  on  the 
putrefying  stools  of  cholera,  and  on  these  only.  It  has 
the  form  of  a  mycelium,  the  tapering  ends  of  which  are 
surmounted  by  cup-shaped  sporangia,  which  burst  on  the 
slightest  agitation,  discharging  vast  numbers  of  spores. 
These  spores  require,  for  their  germination,  to  be  de- 
posited on,  or  to  come  into  contact  with,  some  putrid 
organic  matter,  when  they  develop  into  a  mucor  of 
another  form,  an  anaSrobium,  which  they  believe  to  be 
the  immediate  cause  of  the  phenomena  of  the  disease, 
and  which  again,  in  its  turn  sporifying,  gives  birth  to  the 
bacilli  of  Koch. 

The  bacilli  in  themselves  are  innocuous,  but,  deposited 
on  a  putrid  medium,  and  in  contact  with  the  air,  they 
develop  the  first-mentioned  mucor,  and  the  cycle  is  re- 
newed. 

The  first  mucor,  unlike  the  bacillus,  possesses  in  a 
high  degree  the  power  of  resisting  the  action  of  so-called 
disinfectants  ;  it  is  not  killed  by  ten-per-cent.  solutions     , 
of  nitric  or  of  hydrochloric  acid ;  it  vegetates  freely  in  a     ] 
solution  of  carbolic  acid  in  like  proportions,  and  can  sus-     j 
tain  any  temperature  up  to  150°  Cent  (302®  Fahr.),  but 
above  this  it  breaks  up,  as  it  does  also  in  a  ten-per-cent 
solution  of  tincture  of  iodine ;  and  a  specimen  mounted 
in  oil  of  turpentine  went  through  its  whole  development 
up  to  the  discharge  of  its  spores. 

The  British  Medical  Journal  is  inclined  to  give  some 
credence  to  the  above-described  account.  It  appears  to 
us,  however,  to  be  beyond  the  bounds  of  probability  that 
the  cholera  bacillus  should  have  any  such  life-history 
as  the  Marseilles  investigators  assert.  Dr.  Koch  culti- 
vated it  in  gelatine,  in  broths,  and  on  potato,  yet  never 
found  any  such  mucor  as  MM.  Maurin  and  Lange  de- 
scribe. 


EXAMINATION  FOR  ALBUMINOSE  OR  PEPTONE  IN  ^ 
THE  URINE. 

In  1872  Tanret  proposed,  as  a  reagent  for  the  quan- 
titative determination  of  the  albumen,  the  acetic  solu- 
tion of  the  iodide  of  mercury  and  potash,  of  which  the 
formula  is  iodide  of  potassium,  3.32  grms. ;  bichloride  of 
mercury,  1.35  grm. ;  acetic  acid,  20  c.c. ;  and  distilled 
water,  64  cc.  As  an  agent  for  the  precipitation  of  al- 
bumen, says  Mehn,  this  reagent  is  valuable  ;  it  does  not 
precipitate  urea  or  mineral  salts  ;  it  is  very  sensitive  and 
much  superior  to  nitric  acid,  needs  no  heat  and  keeps 
well. 

Three  years  ago  Mehn  discovered  that  this  solution 
precipitates  the  proteid  material  known  as  albuminose 
or  peptone.  In  examining  a  very  limpid  acid  urine, 
shaken  until  quite  frothy,  he  has  found  that  afler  separ- 
ating the  albumen  coagulable  by  heat,  a  certain  degree 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


351 


of  agitation  still  caused  considerable  frothiness.  The 
urine  contained  neither  pus,  sugar,  nor  blood,  yet  the 
solution  caused,  in  this  urine  deprived  of  albumen,  an 
abundant  precipitate,  which  water  acidulated  with  acetic 
acid  and  alcohol  did  not  dissolve.  Furthermore,  he  has 
several  times  examined  urines  which  contained  no  albu- 
men, but  only  albuminose  or  peptone  coagulable  by  this 
reagent,  and  also  a  mixture  of  coagulable  and  non-co- 
agulable  albumen.  In  some  specimens  of  urine  he  has 
found  coagulable  albumen ;  this  being  removed  the  urine 
was  still  feebly  clouded  by  nitric  acid.  This  second 
cloud  being  removed,  he  obtained  an  abundant  precipi- 
tate, due  to  peptone,  by  the  acetic  solution  of  the  iodide 
of  mercury  and  potassium. 

Various  attempts  have  been  made  to  extract  the 
whole  of  the  coagulable  or  non-coagulable  albuminous 
material  with  five  volumes  of  alcohol,  after  acidulating 
with  acetic  acid,  and  also  to  obtain  the  albuminose  of  a 
liquid  deprived  by  heat  and  filtration  of  coagulable  albu- 
men. It  has  been  found  that  the  results  are  of  no  value, 
since  the  peptone  is  not  altogether  insoluble  in  the  alco- 
hol The  addition  of  ether  to  the  filtrate  still  gives  an 
albuminous  precipitate.  Nor  have  any  very  satisfactory 
results  been  obtained  by  emplo3ring  neutral  solvents, 
such  as  absolute  alcohol  and  sulphide  of  carbon.  The 
solution  under  consideration  seems  to  give  the  best  re- 
sults. Specimens  of  urine  containing  peptone  seem  to 
be  rare,  although  some  observers  seem  to  think  that  the 
cloudiness  caused  by  the  mercury  reagent  in  boiled  urine 
is  entirely  due  to  that  body. 

At  present  we  do  not  possess  any  means  of  isolating 
albuminose  or  peptone,  other  than  those  which  com- 
bine with  the  materials  from  which  it  seems  impossible  to 
separate  it  without  altering  it ;  and  the  rules  which  ap- 
ply to  ordinary  or  artificial  peptones  do  not  apply  to 
urine  peptones,  and  cannot  until  the  identity  of  the  two 
has  been  demonstrated,  which  has  not  as  yet  been  done. 
While  it  is  theoretically  admitted  that  all  albuminous 
materials  subjected  to  the  action  of  pepsin,  at  a  suffi- 
ciently elevated  temperature,  finally  gave  a  peptone 
whose  centesimal  composition  is  constant,  it  is  not  the 
less  true  that  under  the  name  peptones  are  embraced 
products  distinguished  by  their  different  reactions  with 
the  same  reagents.  Peptones  obtained  by  the  action  of 
pepsin  are  precipitated  by  the  iodide  of  mercury  and 
potassium  solution,  whilst  those  obtained  by  the  action 
of  pancreatine  are  not. 

This  solution  is  also  quite  sensitive  to  the  presence  of 
semen  in  urine,  giving  a  precipitate  which  is  more  or 
less  abundant.  While,  therefore,  a  valuable  reagent  for 
the  detection  of  peptone,  it  should  be  used  with  great 
care,  as  errors  may  result  fi-om  the  formation  of  other 
precipitates. 

PUERPERAL  EPILEPSY. 
Thb  older  writers,  says  M.  Ch.  F6r6,  believed  eclampsia, 
whether  infantile  or  puerperal,  to  be  a  neurosis  analo- 
gous to  epilepsy  or  hysteria.  But  since  it  has  been  dis- 
covered that  in  scarlatina  and  pregnancy  there  is  often 
albuminuria,  it  has  been  the  custom  to  explain  all  cases 
of  eclampsia  in  these  conditions  by  the  action  of  the 
poisoned  blood  upon  the  nerve-centres.  M.  F6r6  has 
brought  forward  in  the  Archives  de  Neurologie  of  July, 


1884,  some  observations  and  reasons  in  support  of  the 
view  that  puerperal  eclampsia,  for  example,  is  the  expres- 
sion of  a  neuropathic  state  in  which  the  conditions  in 
pregnancy  are  only  the  exciting  cause.  Puerperal 
eclampsia,  he  thinks,  may  be  regarded  as  an  acute  epi- 
lepsy or  an  *'  eclamptic  epilepsy." 

If  the  antecedents  be  carefiilly  inquired  into,  in  cases 
of  puerperal  eclampsia,  there  will  generally  be  found, 
says  F^r6,  a  hereditary  or  acquired  neuropathic  history. 
A  number  of  cases  are  cited  also  in  which  the  puerperal 
eclampsia,  so-called,  was  only  the  beginning  of  a  chronic 
idiopathic  epilepsy. 

The  influence  of  pregnancy  upon  the  course  of  epilepsy 
has  been  investigated  by  several  observers  with  some- 
what contradictory  results.  On  the  whole,  however,  it 
appears  that  during  pregnancy  the  number  of  epileptic 
attacks  is  diminished.  It  is  also  well  known  that  epilep- 
tics, and  "  neuropathies "  generally,  often  pass  through 
pregnancy  and  even  scarlatina  without  any  convulsion. 
In  explanation  of  these  facts,  however,  Ykxk  puts  for- 
ward the  view  that  in  those  disposed  to  epileptic  attacks 
there  exist  various  epileptogenic  zones,  €,g,^  gastric, 
uterine,  peripheral,  etc  In  some  cases  the  irritation 
must  be  gastric  or  peripheric,  in  other  cases  uterine,  in 
order  to  excite  the  paroxysm  and  call  forth  the  disease. 
It  is  known  that  in  puerperal  eclampsia,  albuminuria 
does  not  always  exist  Thus  Charpentier  alone  dtes  one 
hundred  and  forty-one  cases  of  this  kind  (*'  Traits  pra- 
tique des  accouchements,"  1883).  And  Nothnagel  admits 
that  puerperal  eclampsia  b  sometimes  the  result  of  an 
irritation  of  the  uterine  or  sacral  nerves  acting  upon  an 
unstable  nervous  system. 

Finally,  many  persons  suffer  from  albuminuria  and 
some  degree  of  uraemia  without  having  convulsions. 

M.  F6r6  has  made  out  a  case,  therefore,  which  deserves 
some  attention.  Physicians  should  not  be  too  ready  to 
ascribe  puerperal  eclampsia  entirely  to  blood-poisoning. 
They  ought  to  be  especially  watchful  when  patients  who 
are  pregnant  have  a  well-marked  neuropathic  history. 
At  the  same  time,  practical  experience  shows  that  the 
large  majority  of  nervous  and  hysterical  women  go 
through  pregnancy  safely,  showing  that  the  pregnant 
uterus  does  not  often  become  an  epileptogenic  zone. 


INFANT    FEEDING. 


Upon  nothing  does  there  seem  just  now  to  be  more 
disagreement  than  the  subject  of  infant  diet  The 
points  in  dispute  are :  the  mode  of  diluting  cows'  milk 
and  the  best  diluent ;  the  use  of  mixed  milk  or  of  the 
milk  from  a  single  cow ;  the  value  of  condensed  milk ; 
the  value  of  infant  foods ;  the  question  of  a  wet-nurse 
or  artificial  feeding.  These  points  are  by  no  means  sat- 
isfieictorily  settled.  One  evidence  of  this  is  seen  in  the 
letters  which  appear  in  the  present  issue  of  The  Record. 
We  observe,  also,  in  a  current  issue  of  The  Lancet  and 
Clinic^  a  carefully  written  article  by  Dr.  C.  W.  Earle,  in 
which  he  says,  among  other  things,  that  <'  condensed 
milk  seems  to  agree  with  a  considerable  number  of  chil- 
dren, but  in  many  cases  a  sufficient  quantity  is  not  given 
to  nourish  a  child.  Used  in  sufficient  quantities,  and 
diluted  with  rice-  or  barley-water,  it  is  without  doubt  one 
of  the  best  of  artificial  foods."     On  the  other  hand,  the 


352 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


editor  of  The  Kansas  City  Medical  Record,  in  an  exceU 
lent  article  upon  the  subject  of  infant  diet,  states  that 
condensed  milk  has  always  proved  hurtful  in  his  hands. 
Some  contributions  from  our  readers  to  this  subject  of 
infant  feeding  would  be  timely.  Writers  should,  how- 
ever, be  careful  not  to  go  over  old  ground  more  than 
possible. 


PATIENTS   FROM  THE   COUNTRY    OBTAINING   ADVICE 
FREE  IN  THE  CITY. 

The  thricetold  tale,  yet  always  of  painful  interest  to 
the  stmggling  rural  practitioner,  concerning  the  abuse  of 
medical  charity,  comes  to  us  from  Connecticut  in  a 
communication  from  Dr.  Donaldson  to  the  Medical  So- 
ciety of  the  County  of  New  York.  We  are  glad  to  refer 
to  the  practice,  that  we  may  condemn  it. 

It  appears  useless  to  say  that  rich  patients  from  the 
country  have  no  right  to  gratuitous  services.  They  come, 
nevertheless,  and  the  college  clinics  and  hospital  wards 
welcome  them  with  an  eager  cordiality  not  to  be  mis- 
taken. It  is  safe  to  say  that  it  is  impossible  to  find  out 
the  pecuniary  liability  of  every  stranger,  but,  with  a  little 
care  on  the  part  of  clinical  lecturers  and  hospital  men, 
the  evil  can  be  very  much  lessened.  It  is  perfectly  com- 
petent for  such  gentlemen  to  refuse  to  prescribe  for 
Any  but  the  really  needy;  but,  we  regret  to  say,  the 
thirst  for  clinical  material  overcomes  many  other  con- 
siderations, and  we  oftentimes  find  ourselves  preaching 
in  vain,  and  are  as  far  from  a  remedy  as  ever. 


i:ewB  tit  Wit  ^aetjeeii. 


The  Management  of  the  New  York  Polyclinic, 
have  during  the  past  summer  made  some  improvements 
which  have  added  greatly  to  the  capacity  of  the  school 
and  the  comfort  of  the  physicians  who  study  there.  The 
library,  waiting-  and  reading-  rooms  have  been  enlarged 
and  newly  and  neatly  furnished.  The  clinic-room  for 
diseases  of  the  throat,  nose,  eye,  and  ear  has  been  made 
iwice  the  former  size,  and  has  now  thirty-one  stalls  and 
Mackenzie  condensers,  which  as  many  students  can  em- 
ploy at  once.  On  the  second  floor  are  three  large,  iwell- 
lighted  and  ventilated  lecture-  and  clinicrooms,  capable 
■of  seating  in  all  three  hundred  persons,  a  laboratory 
with  twenty  stands,  two  waiting-rooms  for  patients,  and  a 
private  examining-room.  The  school  has  been  furnished 
with  stationary  and  portable  batteries,  electric  bells  and 
-clocks,  which  are  sounded  at  the  hours.  In  one  amphi- 
theatre the  clinics  in  gynecology,  surgery,  and  skin 
<iiseases  are  held.  The  second  lecture-room  is  devoted 
to  clinics  in  diseases  of  children,  diseases  of  the  mind 
And  nervous  system,  and  orthopedic  surgery.  A  third 
room  is  used  for  diseases  of  the  chest,  physical  diagnosis, 
general  medicine,  and  practice  in  surgical  dressings, 
bandaging,  etc.  During  last  session,  as  shown  by  the 
catalogue,  one  hundred  and  eighty-two  practitioners 
studied  at  the  Polyclinic.  The  purchase  of  the  large 
property  heretofore  in  part  occupied  by  the  Polyclinic, 
means  that  the  management  believe  in  the  future  of  this 
institution.  During  the  coming  year  the  following 
clinics  will  be  given  weekly :  gynecology,  surgery,  dis- 
eases of  children,  diseases  of  the   skin,  diseases  of  the 


mind  and  nervous  S3r8tem,  eye,  throat,  nose,  and  ear, 
clinical  chemistry,  obstetrics,  chest,  diagnosis,  and  medi- 
cine. 

Mr.  Lawson  Tait,  who  has  been  on  a  brief  visit  to 
this  country,  sailed  for  his  home  on  Saturday  last.  On.  the 
Friday  evening  preceding  he  and  Mrs.  Tait  were  enter, 
tained  at  a  dinner  given  in  their  honor  by  Dr.  and  Mrs, 
Fordyce  Barker.  Among  the  other  guests  present  were 
Dr.  and  Mrs.  T.  A.  Emmet,  Drs.  T.  G.  Thomas,  Isaac 
E.  Taylor,  W.  T.  Lusk,  W.  M.  Polk,  A.  A.  Smith,  and 
George  F.  Shrady.  It  is  needless  to  say  that  the  occasion 
was  an  enjoyable  one  to  all  concerned. 

Ramsey  County  Medical  Society  and  the  Death 
OF  Dr.  Stewart. — At  a  special  meeting  of  the  Ramsey 
County  (Minnesota)  Medical  Society,  held  at  Dr.  Stone's 
office,  the  following  resolutions  were  unanimously  adopted : 

WHiereas^  In  the  sad  and  sudden  death  of  Dr.  J.  H. 
Stewart  this  Society  recognizes  its  loss  of  an  esteemed 
and  respected  member ; 

Resolved^  That  we,  his  former  associates,  desire  to  re- 
cord our  sorrow  and  testify  our  warm  appreciation  of  his 
professional  and  manly  qualities.  He  was  learned  and 
more  than  ordinarily  skilful  in  the  practice  of  his  profes- 
sion, endearing  his  patients  to  himself  by  a  most  happy 
faculty.  By  his  death  we  have  lost  a  professional  as- 
sociate, conscientious  and  considerate,  whose  wise  and 
superior  counsel  we  shall  deeply  miss. 

Resolved,  That  we  deplore  the  loss  to  the  community 
of  which  he  was  so  eminent  and  respected  a  member, 
and  whose  trusts  so  frequently  confided  to  him  were  so 
conscientiously  and  honorably  guarded. 

Resolved^  That  we  tender  to  his  greatly  bereaved 
family  our  deepest  sympathy. 

Resolved,  That  a  copy  of  these  resolutions  be  forwarded 
to  the  family,  and  that  they  be  printed  in  the  daily  papers, 
the  Northwestern  Lancet,  and  the  New  York  Medical 
Record. 

An  Office  Fraud  and  Confidence  Man  Abroad. 
— A  young,  short,  thick-set  mulatto  (a  graduate  of  the 
College  of  Physicians  and  Surgeons,  New  York)  is  going 
about  town  obtaining  money  from  physicians  and  others 
on  one  of  many  pretexts  which  appeal  to  one's  sympathy. 
Numbers  have  been  victimized  by  the  scamp.  We  learn 
that  the  fellow  has  been  carrying  on  this  peculiar  business 
for  some  years,  and  that  he  has  served  a  term  in  Sing 
Sing  Prison  for  forging  the  name  of  the  Rev.  Dr.  Deems, 
of  this  city,  on  a  check. 

A  Complimentary  Dinner  was  tendered  to  Dr.  J.  V. 
Shoemaker,  of  Philadelphia,  by  his  friends,  on  his  return 
from  Europe,  at  the  St.  George  Hotel,  on  Saturday  even- 
ing, September  20,  1884. 

American  Gynecological  Society. — The  Ninth  An- 
nual Meeting  of  this  Society  will  be  held  at  the  Palmer 
House,  Chicago,  Tuesday,  Wednesday,  and  Thursday, 
September  30  and  October  i  and  2,  1884. 

Assistant  Physicians  Wanted  in  the  Hudson 
RrvER  State  Hospftau — ^To  fill  a  vacancy  in  the  office 
of  First  Assistant  Physician  at  the  Hudson  River  State 
Hospital,  and  for  the  appointment  of  a  Third  Assistant 
Physician  and  Sanitarian  at  the  said  hospital,  open 
competitive    examinations    of   applicants    for    the  ap> 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


353 


pointments  will  be  held  under  the  rules  of  the  New  York 
Civil  Service  Commission,  Candidates  for  the  positions 
will  be  examined  in  general  medicine  and  surgery ;  in 
psychiatric  medicine ;  in  the  anatomy,  physiology,  and 
pathology  of  the  brain  and  nervous  system  ;  in  the  use 
of  the  microscope  and  instruments  of  precision  ;  in  sani- 
tary science  and  hygiene;  in  foreign  languages;  and 
also  in  regard  to  special  qualifications  for  the  respective 
appointments. 

It  is  required  that  candidates  be  graduates  of  a  repu- 
table medical  college,  and  have  completed  the  term  of 
service  required  by  a  regular  appointment  in  the  resident 
medical  stafif  of  a  general  hospital,  and  that  they  be 
familiar  with  the  practice  of  home  and  foreign  institutions 
for  the  insane. 

There  are  no  restrictions  imposed  as  to  the  residence 
or  citizenship  of  candidates. 

The  examinations  will  be  held  at  such  times  and  places 
as  the  Civil  Service  Commission  may  designate.  Ten 
days'  notice  of  each^examination  will  be  mailed  to  all 
eligible  applicants  of  record,  and  will  be  published  in  the 
State  paper,  and  in  one  other  journal  published  in  Albany. 

Applicants  will  be  admitted  to  examination  upon  the 
production  of  the  official  notification  to  appear  for  that 
purpose. 

The  First  Assistant  Physician  will  receive  $3,000 
salary  per  annum  and  bis  board ;  the  Third  Assistant 
Physician  will  receive  $1,000  salary  per  annum  and  his 
board 

Printed  application  papers  for  admission  to  the  com- 
petitive examinations  will  be  mailed  to  candidates  on 
application  to  Dr.  Joseph  M.  Cleaveland,  Superintendent 
Hudson  River  State  Hospital,  Poughkeepsie,  Dutchess 
County,  N.  Y.  Applications  must  be  forwarded  on  or 
before  October  i,  1884. 

Mississippi  Medical  Society. — The  Tenth  Annual 
Meeting  of  the  Mississippi  Valley  Medical  Society  (**^The 
Tri-State  Medical  Society  ")  will  be  held  at  Springfield, 
III,  September  23-26,  1884. 

American  Public  Health  Association. — ^The  open- 
ing session  of  the  Twelfth  Annual  Meeting  of  the 
American  Public  Health  Association  will  be  held  on 
Tuesday,  October  14th,  in  the  main  hall  of  the  Lieder- 
kranz  Building,  St.  Louis. 

The  National  Conference  of  the  State  Boards  of 
Health,  postponed  from  August  7th,  at  Washington,  will 
also  be  held  here  during  the  same  week. 

Open  to  Universal  Competition. — The  Cartwright 
prize  of  the  Alumni  Association  of  the  College  of  Phy- 
sicians and  Surgeons  of  New  York  is  open  to  the  com- 
petition of  the  alumni  of  any  medical  college. 

It  consists  of  a  prize  of  $500,  to  be  awarded  to 
the  best  medical  essay  submitted  upon  any  subject  the 
writer  may  select.  The  award  will  be  paid  as  soon  as 
the  successful  article  shall  have  appeared  in  print. 

If  no  one  of  the  competing  essays  be  deemed  suffi- 
ciently meritorious  the  prize  will  not  be  awarded.  An 
essay  in  order  to  be  held  worthy  of  the  prize  must  con- 
tain results  of  original  investigation  made  by  the  writer. 
An  award  of  this  prize  will  be  made  at  the  commencement 
of  1885.  Essays  must  be  sent  to  a  member  of  the  Prize 
Committee  before  April    i,    1885.     Competing  essays 


must  each  be  marked  with  a  device  or  motto  and  ac- 
companied by  a  sealed  envelope  similarly  marked  con« 
taining  the  name  and  address  of  the  author. 

IL  W.  Amidon,  M.D.,  18  W.  Twenty-first  Street, 
Chairman;  Robert  Abbe,  M.D.,  32  E.  Twenty-fifth 
Street;  Waiter  Mendelson,  M.D.,  209  W.  Forty-sixth 
Street,  Committee  on  Prize  Essay. 

Victor  Hugo  and  the  Ambulance  Service. — ^The 
establishment  of  an  ambulance  service  like  that  in  New 
York  is  very  nearly  an  accomplished  fact  irf  Paris.  Dr. 
Henri  Nachtel  has  published  a  pamphlet  upon  the  sub- 
ject. It  is  prefaced  by  the  following  characteristic  let- 
ter from  Victor  Hugo  : 

31  JuiUet,  Z884. 

New  York  has  begun,  Paris  will  continue.  That 
which  you  advise.  Monsieur,  is  sustained  by  reason  and  by 
evidence.  Success  will  confirm  your  confidence.  The 
plan  is  clear,  it  is  appropriate,  it  is  humane.  I  com- 
mend you  and  I  congratulate  you.         Victor  Hugo. 

The  Singular  Persistence  with  which  the  Midland 
Medical  Miscellany  continues  to  appropriate  editorials 
and  other  matter  from  The  Medical  Record  without 
acknowledgment  interests  us  very  much.  It  is  fur- 
nishing us  an  exciting  psycho-journalistic  study.  It  is, 
we  think,  an  exquisite  case  of  moral  SchwcUhezusiand^  or 
perhaps  of  imperative  conceptions  (combined  with  pre- 
hensions), there  being  in  its  midland  mind  no  solution  in 
the  general  continuity  of  the  tneum  and  iuum. 

An  Anthropological  Congress  was  held  recently  in 
Breslau.  Among  the  interesting  contributions  made  at 
that  time  was  one  by  Professor  Schaffhausen,  of  Bonn,  who 
has  found,  as  the  result  of  a  series  of  cranial  measurements, 
that  the  antero-posterior  or  longitudinal  growth  of  the 
skull  ceases  before  the  lateral  growth,  and  that  the  lon- 
gitudinal growth  bears  a  distinct  relation  to  that  of  the 
body,  while  the  lateral  growth  stands  in  relation  to  the  in- 
telligence. Here  is  then  a  physical  basis  for  the  school- 
master to  work  upon  in  assigning  his  tasks  and  making 
his  prophecies. 

Prizes  for  Essays  on  the  Prevention  of  Blind- 
ness.— At  the  Hygienic  Congress  held  at  the  Hague, 
August  27th,  a  prize  of  2,000  francs  was  awarded  to  Dr. 
Fuchs,  of  LUttich,  for  an  essay  on  the  **  Causes  and  Pre- 
vention of  Blindness."  The  prize  of  1,000  francs  offered 
for  an  essay  on  a  similar  subject  was  awarded  to  a  Ger- 
man author,  whose  name,  strange  to  say,  could  not  be 
discovered. 

Works  of  the  Late  Dr.  Farr. — A  movement  is  on 
foot  to  collect  and  publish  the  statistical  papers  of  the 
late  Dr.  Farr.     The  editor  will  be  Mr.  Noel  Humphreys. 

The  Hygienic  Congress  at  the  Hague  has  unan- 
imously adopted  the  propositions  of  Professor  Proust 
expressing  the  desirability  of  the  meeting  of  a  new  Inter- 
national Sanitary  Conference  and  the  creation  of  a  per- 
manent international  scientific  committee  to  act  against 
epidemics.  It  has  also  passed  a  resolution  in  favor  of 
an  international  sanitary  code.  Holland  will  be  asked 
to  be  the  interpreter  of  the  views  of  the  Congress  to  the 
other  Governments.  In  the  Second  Section,  on  the  27th 
ult.,  a  long  debate  took  place  upon  cremation.  In  the 
general  meeting  of  the  Congress,  Mr.  Corfield,  of  Lon- 
don, defended  the  axiom  that  science  is  the  enemy  of 


354 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


disease.  M.  Trelat,  of  Paris,  spoke  upon  the  tempera- 
ture which  should  be  maintained  in  dwelling-houses. 
Mrs.  Bovell-Sturge,  of  London,  condemned  the  system 
by  which  at  present  the  State  provides  for  the  education 
of  children  who  have  been  abandoned  by  their  parents, 
and  advocated  their  being  educated  in  private  houses. 

A  New  Hospital  at  Romb. — ^The  Pope  has  given 
$200,000  for  the  erection  of  a  new  hospital  at  Rome 

near  the  Vatican. 

• 

More  Yellow -Fever  Cases  in  New  York  and 
Brooklyn. — Two  sailors  died  of  yellow  fever  at  the 
Long  Island  College  Hospital  last  week.  They  came 
from  the  West  Indies  on  the  British  steamer  African, 
and  landed  at  Perth  Amboy,  N.  J. 

A  steerage  passenger  on  the  Newport,  from  Havana, 
which  arrived  at  this  port  recently,  was  found  at  a  hotel 
on  West  Fourteenth  Street  apparently  suffering  from 
yellow  fever.     He  was  at  once  put  in  quarantine. 

At  this  time  of  year  there  is  no  possible  danger  of 
yellow  fever  extending  through  the  city. 

The  Sanitary  Council  of  Maryland  held  a  suc- 
cessful meeting  at  the  Blue  Mountain  House,  September 
1 7th,  1 8th,  and  1 9th.  Among  the  subjects  discussed  were  : 
"The  Adulterations  of  Food  and  Medicines;"  "The 
Pollution  of  the  Water-courses  in  Maryland;"  "The 
Relation  of  the  Diseases  of  Animals  to  the  Human  Race ;" 
"  The  Sanitary  Problems  of  the  Cities  and  Towns  of 
Maryland ;""  The  Relation  of  the  Press  to  Sanitary 
Work  ;*'  "  The  Relation  of  Teachers  to  Sanitary  Work ;" 
"The  Physical  Dangers  of  Alcoholic  Beverages;"  "The 
Relation  of  the  Clergy  to  Sanitary  Work ;"  "  The  Duty 
of  State  and  Municipal  Governments  in  Connection  with 
the  Public  Health ;"  <*  The  Disposal  of  the  Dead." 

A  Reception  to  Dr.  Playfair,  of  Lopdon,  was 
tendered  by  Dr..  T.  Addis  Emmet  at  his  residence  in  this 
city,  on  September  26th. 

Medicine  at  Winnipeg,  Manitoba. — A  correspondent 
of  the  Canadian  Practitioner  writes  :  "  Manitoba  has 
been  making  the  same  rapid  strides  in  medical  matters 
as  in  all  other  departments.  With  the  rapid  influx  of 
people  came  an  equally  rapid  increase  of  doctors,  until 
we  can  boast  of  the  largest  proportion  of  medical  men  to 
the  total  population  of  any  province  in  the  Dominion. 
Indeed,  at  present,  the  field  is  too  well  occupied,  espe- 
cially in  our  cities  and  towns.  Without  doubt,  however, 
there  are  many  points  in  rural  districts  where  a  doctor's 
presence  would  be  hailed  with  pleasure,  and  where  he 
could  make  a  present  living  and  be  reasonably  sure  of  a 
future  reward  commensurate  with  the  arduous  nature  of 
his  early  work."  Winnipeg  having  got  a  medical  school 
started,  is  soon  to  have  a  hospital. 

Doctors  in  Canada  and  the  United  States. — 
There  are,  says  Dr.  Sullivah,  three  thousand  five  hundred 
and  seven  physicians  in  Canada,  or  one  to  about  fifteen 
hundred  inhabitants.  Indiana  with  about  the  same  popu- 
lation as  Ontario,  has  three  thousand  two  hundred  and 
seventy-five  more  doctors.  Canada  has  about  nine  hun- 
dred medical  students  distributed  among  eight  medical 
schools. 


The  Philadelphia  Maternity  Hospital.— The  ob- 
stetrical staff  of  this  hospital  has  filed  a  petition  with  the 
managers  asking  for  the  appointment  of  a  female  resident 
physician. 

The  MosQurro  as  a  Yellow  Fever  Vaccinator.— 
The  editor  of  the  St,  Louis  Courier  of  Medicine  gives  an 
account  of  the  studies  of  Dr.  Carlos  Finlay  {Cronica 
Medico  quirurgica  de  la  Habana\  with  reference  to  mos- 
quitoes and  yellow  fever.  Dr.  Finlay  believes  that  he 
has  demonstrated  that  yellow  fever  is  inoculable  by  the 
sting  of  the  Cuban  day-mosquito  during  the  third,  fourth, 
fifth  and  sixth  days  of  its  evolution,  but  not  during  the 
first  two  days  nor  after  the  sixth,  no  matter  what  be  the 
severity  of  the  symptoms  at  those  periods.  The  dura- 
tion of  incubation  ofifers  the  same  variations  in  the  inocu- 
lated as  in  the  natural  disease,  in  either  case  varying 
from  five  to  twenty-four  days.  The  duration  and  inten- 
sity of  the  fever  produced  by  inoculation  by  the  mosquito 
appears  to  be  in  proportion  to  the  number  of  punctures 
and  the  quantity  of  inoculable  matter  retained  by  the  in- 
sect's sting.  The  inoculation  by  one  or  two  punctures 
in  no  case  produced  any  other  morbid  phenomena  than 
those  of  benign  natural  yellow  fever.  Dr.  Finlay  thinks 
that  the  results  already  obtained  warrant  the  assertion 
that  the  inoculation  of  yellow  fever  by  one  or  two  mos- 
quito bites  is  a  plausible  means  of  imparting,  without 
peril,  immunity  against  the  severe  forms  of  the  disease  to 
which  those  are  exposed  who  dwell  in  an  infected  dis- 
trict. 

Through  Quarantine. — Our  India  medical  exchanges 
smell  so  strongly  of  smoke  and  carbolic  acid  as  to  give  a 
realistic  sensation  of  the  existence  of  an  epidemic. 

A  School  of  Dentistry  is  to  be  opened  at  the  be- 
ginning of  the  winter  term  at  the  University  of  Leipzig, 
under  the  direction  of  Professor  Dr.  Fr.  Hesse. 

The  Medical  Department  of  the  Prussian  War 
Ministry,  assisted  by  the  Medical  Department  of  the 
Bavarian  and  Wurtemberg  War  Ministries,  and  the  Saxon 
Sanitary  Board,  are  now  bringing  out  a  sanitary  report  of 
the  German  armies  in  the  Franco-German  war  of  1870- 
71.    The  first  and  fourth  volumes  have  just  appeared,    r 

Mr.  Tait's  Tribute  to  the  Medical  Colleges.— 
Mr.  Lawson  Tait  has  heralded  his  entrance  to  this  coun- 
try by  some  very  flattering  remarks.  He  wishes  now 
that  he  had  come  to  America  instead  of  Germany  to 
finish  his  medical  education;  and  he  prophesies  that 
"  ere  long  it  will  be  to  the  medical  schools  of  America 
rather  than  of  Europe  that  English  students  will  travel, "* 
before  settling  in  practice.  This  is  very'complimentary, 
and  it  has  already  been  appropriated  by  some  of  our 
contemporaries  as  a  truthful  tribute  to  the  medical  col- 
leges of  the  United  States,  although  Mr.  Tait  had  not 
left  the  Dominion  when  he  made  the  remark.  Let  us 
not  be  too  easily  caught  by  a  somewhat  overloaded  com- 
pliment. 

Dermatology  in  Paris  and  Vienna. — For  a  long 
time  it  has  been  noticeable  that  whoever  writes  letters 
from  medical  Vienna  is  sure  to  say  a  great  deal  about  the 
dermatological  teaching.  Vienna  has  certainly  won  pre- 
eminence through  the*world  in  this  department  of  raedi- 


September  27,  1884.] 


THE  MEDICAL  RECORD. 


355 


cine.  In  a  recent  issue  of  Le  Progrls  Medical  thejjd- 
itor  devotes  a  long  article  to  the  subject  of  the  decadence 
of  dennatology  in  Paris,  and  its  flourishing  condition  in 
^enna.  In  Paris  dennatology  is  at  a  low  ebb  because 
the  clinics  are  not  well  organized  and  the  material  at  dis- 
posal not  utilized.  There  seems  to  be  a  good  deal  of 
official  dulness  and  obstruction  at  the  bottom  of  it  all. 
In  Vienna  the  clinics  are  well  organized,  the  material  is 
centralized,  and  all  can  be  made  use  of.  Perhaps  the 
large  excess  of  ignorance,  filth,  and  syphilis  has  some- 
thing to  do  with  tbe  brilliancy  of  the  skin  clinics.  Vienna, 
though  a  great  medical  centre,  has  one  of  the  highest 
mortality  rates  in  Europe.  Le  JProgrh  Medical  advises 
the  reorganization  of  the  H6pital  St.  Louis,  which  con- 
tains a  wealth  of  dermatological  material. 

Instruction  in  the  Methods  of  Examining  Micro- 
organisms.— It  is  well  known  that  the  ordinary  examina- 
tion of  fluids  and  tissues  for  micro-organisms  does  not 
involve,  generally,  any  very  delicate,  or  complex  pro- 
cedures. No  doubt  in  time  a  practical  acquaintance 
with  these  details  will  be  thought  as  necessary  to  the 
student  as  dissection.  Educational  institutions  already 
3ee  the  need  of  teaching  '*  bacteriology.''  Recently  the 
Berlin  Government  has  taken  a  new  step.  Herr  von 
Gossler,  Minister  of  Public  Worship,  Education,  and 
Medical  Affairs,  has  ordered  that  a  certain  number  of 
medical  men  are  to  be  summoned  to  Berlin  every  year, 
to  go  through  a  course  of  study,  lasting  from  a  fortnight 
to  three  weeks,  in  order  to  learn  the  new  methods  of  in- 
vestigation connected  with  bacteria  and  micro-organisms, 
but  chiefly  to  become  acquainted  with  everything  con- 
nected with  the  comma-bacillus  and  the  methods  of 
cultivating  it  according  to  Koch's  method.  The  several 
Federal  Governments  have  been  already  requested  to 
select  a  number  of  medical  men  for  this  course,  and  to 
inform  them  to  hold  themselves  in  readiness  to  come  to 
Berlin.  The  day  for  the  commencement  of  the  first 
course,  says  the  British  Medical  Journal^  has  not  yet 
been  fixed,  but  will  be  very  shortly. 

The  CHOLERA.-^The  epidemic  continues  to  decline. 
The  number  of  cases  reported  in  Italy,  September  17th, 
was  581  ;  a  week  later  the  number  was  435.  During 
the  same  time  the  daily  number  of  new  cases  in  Naples 
has  fallen  from  463  to  251.  The  total  number  of  deaths 
from  cholera  in  Italy  up  to  September  24th  was  7,212. 
This  represents  fully  twice  that  number  of  cases.  The 
mortality  in  the  past  weeks,  if  correctly  given,  has  aver- 
aged over  fifty  per  cent.,  showing  that  the  disease  is  very 
malignant  or  treatment  is  very  ineflectual.  It  is  prob- 
able, however,  that  the  number  of  cases  reported  is  much 
below  the  truth. 

In  the  south  of  France  the  cholera  continues  to  at- 
tack small  towns,  but  with  no  great  severity.  There  have 
as  yet  been  only  about  300  cases  in  Spain,  and  these 
chiefly  in  the  Eastern  Pyrenees. 

CuiciDE  OF  A  Medical  Student. — Mr.  John  F.  Keat- 
ing, a  medical  student  in  the  Medical  Department  of  New 
York  University,  committed  suicide  last  week  by  shoot- 
ing himself  with  a  pistol.  The  cause  given  by  him  was 
the  sickness  and  approaching  death  of  his  mother.  It 
seems  probable  that  he  was  not  sane  at  the  time. 


THE  SIMS  MEMORIAL  FUND. 

To  the  Medical  Profession  and  Others  throughout  tht 
World: 

The  great  achievements  of  Dr.  J.  Marion  Sims  call 
for  some  more  lasting  testimonial  than  obituaries  and 
eulogies.  To  him  medical  science  is  indebted  for  much 
brilliant  and  original  work,  especially  in  gynecological 
surgery.  Those  who  have  been  benefited  by  his  teach- 
ings and  new  operations,  and  such  as  have  had  the  direct 
advantage  of  his  personal  skill  are  among  the  first  to 
recognize  and  acknowledge  this  debt 

To  him  is  due  the  honor  of  giving  the  first  strong  im- 
pulse to  the  study  of  gynecological  surgery  in  America. 

It  is  believed  that  the  medical  profession  everywhere, 
the  vast  number  of  women  who  owe  their  relief  firom 
suffering  directly  to  him,  and  those  who  realize  the 
benefits  he  first  made  possible,  will  gladly  unite  thus  to 
honor  the  man  through  whose  originsd  and  inventive  ge- 
nius such  blessings  have  been  conferred  upon  humanity. 

At  the  suggestion  of  many  fiiends,  therefore,  the  sub- 
joined committee  has  been  organized,  and  it  is  proposed 
that  a  suitable  monument  be  erected  to  his  memory  in 
the  city  of  New  York. 

To  this  end  the  active  co-operation  of  the  medical 
profession  and  the  many  other  friends  of  Dr.  Sims 
throughout  the  world  is  respectfiiUy  solicited.  Contribu- 
tions of  one  dollar  and  upward  may  be  forwarded  to  the 
journal  which  has  been  constituted  the  treasury  of  this 
fund — ^The  Medical  Record,  New  York. 

FORDYCE  BARKER,  M.D.,  Chairman. 
GEORGE  F.  SHRADY,  M.D.,  Secretary. 

Thomas  Addis  Emmet,  M.D.,  New  York. 
T.  Gaillard  Thomas,  M.D.,  " 

William  T.  Lusk,  M.D.,  " 

William  M.  Polk,  M.D.,  " 

Paul  F.  MundA,  M.D.,  " 

S.  O.  Vander  Poel,  M.D.,  " 

Frank  P.  Foster,  M.D.,  « 

E.  S.  Gaillard,  M.D.,  " 

Alex.  J.  C.  Skene,  M.D.,  Brooklyn,  N.  Y, 
Samuel  D.  Gross,  M.D.,  Philadelphia,  Pa. 
William  Goodell,  M.D.,  " 

James  R.  Chadwick,  M.D.,  Boston,  Mass. 
William  H.  Byford,  M.D.,  Chicago^  III 
A.  Reeves  Jackson,  M.  D.,       " 
Thad.  a.  Reamy,  M.D.,  Cincinnati,  O. 

C.  D.  Palmer,  M.D.,  " 

George  J.  Engelmann,  M.D.,  St.  Louis,  Mo. 
R.  Beverley  Cole,  M.D.,  San  Francisco,  Cal. 
H.  F.  Campbell,  M.D.,  Augusta,  Ga. 
R.  B.  Maury,  M.D.,  Memphis,  Tenn. 
E.  S.  Lewis,  M.D.,  New  Orleans,  La. 
J.  T.  Searcy,  M.D.,  Tuskaloosa,  Ala. 
R.  A.  Kinloch,  M.D.,  Charleston,  S.  C. 
Hunter  Maguire,  M.D.,  Richmond,  Va« 
S.  C.  Busey,  M.D.,  Washington,  D.  C. 
Harvey  L.  Byrd,  M.D.,  Baltimore,  Md. 
W.  T.  Howard,  M.D.,  " 

D.  ^W.  Yandell,  M.D,,  Louisville,  Ky. 
Seth  C.  Gordon,  M.D.,  Portland,  Me. 
Frank  E.  Beckwith,  M.D.,  New  Haven,  Conn, 
A.  W.  Knox,  M.D.,  Raleigh,  N.C. 

L.  W.  Oakley,  M.D.,  Elizabeth,  N.  J. 
A.  T.  Woodward,*  M.D.,  Brandon,  Vt. 
Albert  H.  Crosby,  M.D.,  Concord,  N.  H. 

E.  S.  DuNSTER,  M.D.,  Ann  Arbor,  Mich. 
Alex.  J.  Stone,  St.  Paul,  Minn. 

Additional  List  of  Subscribers. 

A.  R.  Carman,  M.D.,  New  York $5  00 

A.  R.  Mott,  Sr.,  M.D.,  Leesburg,  Va 1  00 

Nelson  G.  West,  M.D.,  "  i  00 

Hubert  Haywood,  M.D.,  Raleigh,  N.  C 5  00 

Henry  Griswold,  M.D.,  New  York 25  00 

R.  C.  McCorkhiil,  M.D.,  West  Famham,  Canada.     1  50 


356 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


^exriewrs  and  g^otices* 


Osteotomy  and  Osteoclasis  for  Deformities  of  the 
Lower  Extremities.  By  Charles  T.  Poore,  Sur- 
geon to  St.  Mary's  Free  Hospital  for  Children,  New 
York.  8vo,  pp.  187.  New  York  :  D.  Appleton  &  Co. 
1884. 

Dr.  Poore,  who  has  already  become  so  well  known  by 
journal  articles  on  bone  surgery,  has  condensed  his  ex- 
perience in  the  work  before  us.  He  has  succeeded  in 
doing  this  in  a  very  satisfactory  way.  He  has  gone  over 
the  subject  in  a  very  thorough  manner,  thus  giving  a 
concise  treatise  on  osteotomy.  This  has  been  very  much 
needed,  considering  the  rapid  progress  which  has  been 
made  in  this  department  of  surgery  within  the  last  few 
years,  and  the  number  of  articles  of  rare  value  which 
have  been  scattered  through  the  journals.  Dr.  Poore 
has  not  only  described  in  a  very  intelligent  and  concise 
manner  all  the  different  methods  of  osteotomy  advocated 
by  the  leading  surgeons  abroad,  but  has  studied  the  same 
from  the  light  of  a  personal  experience  which  has  been 
sufficiently  large  for  purposes  of  deduction  and  analysis. 
He  is  not  backward  in  stating  his  preferences  regarding 
procedures,  but  he  does  so  with  becoming  respect  for  the 
opinions  of  others,  and  with  a  modest  candor  which  is 
quite  convincing.  There  is  manifested  throughout  a  dis- 
position to  give  the  facts  to  the  reader  with  such  conclu- 
sions as  can  be  legitimately  drawn  from  them. 

Dr.  Poore  speaks  strongly  in  favor  of  the  chisel  as 
against  the  saw,  for  the  performance  of  osteotomy.  The 
obvious  reason  for  this  is  that  he  has  never  used  any 
variety  of  saw,  and  is  particularly  skilful  with  a  chisel  of 
his  own  device,  which,  by  the  way,  is  a  perfect  instru- 
ment of  its  kind.  It  is  a  matter  of  personal  preference 
for  the  chisel,  which  he  has,  under  the  circumstances,  a 
perfect  right  to  maintain.  It  is  needless  to  follow  the 
author  through  the  various  stages  of  his  work  ;  suffice  it 
to  say,  however,  that  he  puts  his  points  fairly,  and  draws 
his  conclusions  logically  as  to  methods  of  treatment  re- 
commended. His  advocacy  of  MacEwen's  supra-con- 
dyloid  operation  is  what  might  be  expected,  and  is  in 
full  accord  with  the  verdict  of  the  surgical  section  of  the 
late  meeting  of  the  International  Medical  Congress.  We 
cannot  too  strongly  commend  the  clear  and  succinct 
manner  in  which  the  author  weighs  the  indications  for 
treatment  in  particular  cases.  In  so  doing  he  shows  a 
knowledge  of  his  subject  which  is  as  extensive  as  it  is 
profound,  and  no  one  at  all  interested  in  orthopedy  can 
read  his  conclusions  without  profit.  His  own  cases,  which 
are  carefully  reported,  are  valuable  additions  to  the  liter- 
ature of  the  subject.  These,  together  with  others,  which 
are  only  summarized,  contain  so  much  practical  informa- 
tion and  sound  surgery  that  they  give  a  special  value  to 
the  work,  altogether  independent  of  its  other  excellences. 
It  is  a  good  book  in  every  way,  and  we  congratulate  the 
author  accordingly. 

Atlas   of  Female   Pelvic  Anatomy.    By  D.  Berry 
Hart,  M.  D.,  Lecturer  on  Midwifery  and  Diseases  of 
Women,  School  of  Medicine,  Edinburgh,  etc.     With 
Preface  by  Alexander  J.  C.  Skene,  M.D.,  Professor 
Medical  and  Surgical  Diseases  of  Women,  Long  Island 
College  Hospital,  Brooklyn,  N.  Y.    4to,  pp.  89.    New 
York  :  D.  Appleton  &  Co.     1BS4. 
^*  In  this  Atlas,"  says  the  author  in  his  preface,  "  I  have 
tried  to  give  a  faithful  account  of  the  anatomy  of  the 
female  pelvic  organs."     How  he  has  succeeded  can  only 
be  appreciated  by  a  careful  study  of  the  numerous  mag- 
nificently executed  and  accurately  delineated  plates  to 
be  found  in  this  superbly  printed  volume.     It  is  hardly 
possible  to  give  any  idea  of  their  excellence  by  any  de- 
scription. They  are  simply  magnificent,  and  so  completely 
meet  every  desideratum  of  the  anatomist  and  practical 
surgeon  that  nothing  is  left  to  be  desired.     Very  many 
of  the  drawings  are  original  in  design  and  novel  in  exe- 


cution, illustrating  in  outline  and  detail  many  points  in 
relative  anatomy  not  generally  referred  to  by  leading 
authorities,  and  in  every  particular,  so  far  as  we  know  to 
the  contrary,  bringing  our  knowledge  up  to  the  level  of 
the  latest  investigations  of  the  anatomy  of  the  parts,  de- 
scriptive and  topographical.  Take,  for  instance,  the  study 
of  the  female  perineum,  the  reflections  of  the  pelvic 
fascia  and  natural  relations  of  the  healthy  uterus.  Many 
of  the  plates  are  beautifully  colored,  with  the  principd 
organs  indicated  by  abbreviated  names  upon  them,  after 
the  manner  of  Gray.  This  lettering  does  not  in  any  way 
interfere  with  the  strikingly  artistic  efifect  of  the  plates  as 
a  whole,  while  they  greatly  aid,  as  will  be  obvious  to 
every  student,  the  proper  study  of  relations  of  diflferenl 
parts  to  each  other  without  constant  reference  to  the 
text.  The  outline  drawings  are  also  models  of  their 
kind  and  do  not  aim  at  giving  too  much  in  one  figure. 
One  point  is  illustrated  al  a  time,  and  the  collection 
makes  a  consistent  whole  with  the  more  elaborately  and 
accurately  detailed  chromo-lithographic  illustrations.  The 
micro-photographic  representations  of  tissue  formation 
are  well  executed,  but  are  rather  disappointing  in  their 
small  number,  and  in  some  instances  sharpness  of  detail. 
This  is,  however,  only  speaking  comparatively  in  regard 
to  the  other  plates  throu|;hout  the  work. 

The  descriptive  text  is  not  voluminous.  This  would 
hardly  be  considered  necessary  in  a  work  of  this  kind, 
the  main  objects  of  which  are  to  teach  by  the  pencil 
rather  than  by  the  pen.  In  the  higher  walks  of  anatomy, 
where  this  remarkable  atlas  finds  a  leading  place,  there 
is  no  need  for  much  detail  description.  The  student  is 
expected  to  have  mastered  the  elements  and  to  have 
gone  on.  Hence,  evidently  following  out  this  idea,  the 
author  contents  himself  mostly  with  straightforward  de- 
monstrations, giving  only  such  word  descriptions  as  shall 
enable  him  to  make  his  subject  sufficiently  understood 
in  consistent  outline. 

•As  a  new  work  by  a  well-known  author  there  is  a 
natural  prejudice  in  its  favor,  but  this  becomes  the  more 
deeply  rooted  as  we  constantly  get  new  views  of  old  fields, 
new  landmarks  for  better  outlooks,  new  light  upon  here- 
tofore obscure  points.  To  particularize  would  be  to  re- 
view all  the  recent  advances  made  by  leading  anatomists 
in  the  study  of  female  pelvic  anatomy — a  detail  which 
would  be  for  the  purpose  of  this  notice  plainly  unneces- 
sary. In  a  word,  we  can,  after  the  most  critical  study  of 
its  contents,  say  with  the  distinguished  editor,  Professor 
Skene,  that  'Mt  is  far  in  advance  of  any  work  of  its  kind 
yet  produced."  As  such  it  becomes  a  necessity  for  the 
progressive  gynecologist,  for  the  operating  surgeon,  and 
for  the  leading  general  practitioner.  We  congratulate  the 
publishers  on  the  reproduction  of  this  grand  work  and 
bespeak  for  it  a  becoming  appreciation  by  the  profession 
of  this  country. 

Lessons  in  Longevity  :  Paragraphs  on  Home  Hygiene 
and  the  Art  of  Prolonging  Life.  By  John  B.  Hamil- 
ton, M.D.  Washington:  William  H.  Morrison.  1884. 
This  modest  little  pamphlet  contains  much  sound  sense 
as  well  as  sanitary  wisdom.  The  author  possesses  a 
graceful  style  and  knows  how  to  adorn  his  texts,  mingling 
du/ce  et  utile. 


Origin  of  Eating  Goose  on  Michaelmas  Day.— 
Queen  Elizabeth  on  her  way  to  Tilbury  Fort  on  Septem- 
ber 29,  1589,  dined  on  roast  goose  and  Burgundy  wine. 
She  fed  so  heartily  that  she  required  an  extra  half  pint 
of  Burgundy,  with  which  she  drank  "  Destruction  to  the 
Spanish  Armada."  She  had  scarcely  set  her  glass  down 
when  news  came  of  the  destruction  of  the  Spanish  fleet 
by  a  storm.  She  immediately  took  another  bumper  to 
digest  the  good  news  as  well  as  the  goose,  and  ordered 
that  roast  goose  should  be  served  up  to  her  every  year 
on  that  day.  The  court  followed  the  custom,  and  the 
people  generally  soon  adopted  it.  Burgundy  wine  could 
be  taken  at  all  times. 


September  27,  1884. J 


THE  MEDICAL  RECORD. 


357 


%ntevrmtiotml  ptjejflijcal  d^ongxtsB. 

EIGHTH   SESSION. 
Ife/dat  Copenhagen^  Denmark^ August  10-16,  1884. 

REPORTS  OF  SECTIONS. 

SECTION  ON  DISEASES  OF  CHILDREN. 

Monday,  August  iith — First  Day. 

The  Section  was  called  to  order  by  the  President,  Pro- 
fessor Hirschsprung,  of  Copenhagen,  who  welcomed 
the  members,  outlined  briefly  the  work  that  was  to  be 
done,  and  expressed  the  hope  that  the  science  of  pediat- 
rics would  receive  a  new  impetus  from  the  labors  of  the 
eminent  men  who  had  given  their  adherence  to  this  im- 
portant section. 

He  then  announced  the  election  of  the  following  of- 
ficers: 

PRESIDENTS. 

Professors  A.  Jacobi,  of  New  York,  and  Rauchfiiss,  of 
St  Petersburg. 

SECRETARIES. 

Drs.  Israel  and  Wichmann,  both  of  Copenhagen. 
The  Chair  was  then  taken  by  Dr.  Jacobi. 
Dr.  Rauchfuss  read  a  paper  on 

THE   EDUCATIONAL  VALUE   OF  POLICLINICS 

for  the  treatment  of  dieases  of  children.  He  main- 
tained that  not  the  least  of  the  benefits  that  resulted  from 
policlinics  was  the  diffusion  throughout  the  community, 
and  especially  among  the  poor  and  the  ignorant,  of  a 
knowledge  of  hygiene.  If  ignorant  motliers  could  only 
be  impressed  with  the  importance  of  observing  at  least 
the  elementary  rules  of  hygiene,  a  vast  amount  of  good 
would  be  accomplished.  Prevention  was  better  than 
cure. 

Dr.  a.  Baginsky,  of  Berlin,  then  read  a  communica- 
tion entitled 

THE  PATHOLOGY  AND  TREATMENT  OF  CHOLERA  INFANTUM. 

This  disease,  the  author  said,  is  to  be  reckoned,  in  Ber- 
lin at  least,  as  the  chief  cause  of  death  in  infants.  ITie 
number  of  cases  of  the  disease  in  any  given  summer  is  in 
direct  proportion  to  the  height  of  the  temperature  of 
the  air,  but  seems  to  be  only  indirectly  dependent  upon 
the  height  of  the  temperature  of  the  ground,  the  lower- 
ing of  the  level  of  the  ground  water,  or  the  degree  of 
moisture  of  the  atmosphere.  The  quality  of  the  nour- 
ishment and  the  de^ee  of  care  which  the  child  receives, 
as  well  as  the  situation  of  the  dwelling,  are  very  impor- 
tant factors  in  the  etiology.  Teething  has  no  direct  in- 
fluence on  the  disease. 

As  regards  pathology,  the  different  forms  of  summer 
diarrhoea  of  infants  may  be  divided  into  :  1,  primary 
d3rspeptic  catarrh  ;  2,  genuine  cholera  infantum  (chol- 
era nostras) ;  2,  follicular  disease  of  the  intestinal  tract ; 
4,  secondary  dyspeptic  catarrh ;  and  5,  intestinal  atro- 
phy. All  these  processes  are  as  links  in  a  chain,  and 
inay  pass  one  into  the  other.  Post-mortem  examina- 
tions prove  the  correctness  of  this  statement.  Micro- 
organisms are  found  in  the  walls  of  the  intestines,  and 
are  perhaps  not  unconcerned  in  the  causation  of  the  dis- 
ease. The  therapeutic  management  varies  according  to 
the  fomi  of  the  disease  with  which  we  have  to  deal. 

Professor  Hirschsprung,  of  Copenhagen,  then  read 
a  paper  summing  up  the  results  of 

OBSERVATIONS   ON   HiGMOGLOBINURIA 

during  the  first  year  of  life,  and  gave  a  demonstration  of 
this  condition. 

Dr.  H.  Rehn,  of  Frankfort-on-rhe-Main,  followed  with 
a  paper  on 

SO-CALLED  ACUTE   RICKETS, 

in  which  he  attempted  to  answer  the  question  whether 
the  ext>eriences  of  later  years  have  enabled  us  to  deter 


mine  the   position  of   the   affection   known    as   acute 
rachitis. 

Most  of  the  papers  elicited  more  or  less  discussion 
from  those  present. 


No  session  was  held  on  Tuesday,  August  12th,  but 
the  members  of  the  Section,  together  with  those  of  the 
Section  on  Hygiene  and  State  Medicine,  made  an  ex- 
cursion to  the 


ASYLUM    FOR   YOUNG   GIRLS 


at  the  Chateau  Jaegerspris  near  Copenhagen. 


On  Wednesday,  August  13th,  no  meetings  of  Sections 
were  held,  as  all  the  members  of  the  Congress  joined  in 
the  excursions  to  Elsinore  and  other  places. 


Thursday,  August  14TH — Fourth  Day. 

In  the  morning  the  Section  held  a  joint  meeting  with 
that  on  Hygiene  and  State  Medicine. 

Dr.  Schkpelern,  of  Refsnaes,  read  a  paper  on 

the   treatment  of  CHRONIC   DISEASES   OF   CHILDREN  AT 
SEA-COAST   HOSPITALS. 

The  speaker  advanced  the  proposition  that  sea- side 
sanitaria  ought  to  be  kept  open  the  entire  year,  winter 
as  well  as  summer.  He  then  spoke  of  the  good  results 
following  a  winter  course  of  treatment,  dwelling  more 
especially  upon  the  value  of  hydrotherapy  in  this  con- 
nection. Among  the  diseases  of  childhood  in  which 
great  benefit  may  be  derived  by  a  course  of  treatment  at 
sea-side  sanitaria,  the  author  spoke  more  particularly  of 
the  scrofulous  affections.  One  point  upon  which  he 
dwelt  at  some  length  was  the  value  of  an  increase  in 
weight  as  evidence  of  the  favorable  progress  toward  re- 
covery in  scrofula. 

Dr.  Engelsted,  of  Copenhagen,  read  a  second  paper 
on  the  same  subject.  His  views  did  not  differ  substan- 
tially from  those  of  the  preceding  speaker. 

At  the  afternoon  session  Dr.  Rauchfuss,  of  St.  Peters- 
burg, read  a  paper  on 

CROUP, 

in  which  he  argued  the  question  as  to  how  far  this  condi- 
tion can  be  considered,  from  a  clinical  point  of  view,  as 
a  well-defined  morbid  entity. 

A  discussion  followed,  which  was  participated  in  by 
Professor  Virchow,  of  Berlin,  and  others. 


Friday,  August  15TH — ^Fifth  Day. 

Professor  Rauchfuss,  of  St.  Petersburg,  occupied 
the  chair. 

Dr.  Rupprecht,  of  Dresden,  read  a  paper  on  the 

antiseptic  treatment  of  wounds  in  childhood. 

The  author  thought  the  best  disinfectant  was  a  one-third 
per  cent,  solution  of  salicylic  acid,  or  for  very  septic 
wounds,  a  four  to  eight  per  cent,  solution  of  chloride  of 
zinc.  One  of  the  poorest  materials  for  use  in  operations 
on  children  was  carbolic  acid.  The  general  admissibility 
of  corrosive  sublimate  solution  (i  to  1,000)  in  childhood 
was,  he  thought,  questionable.  For  certain  wounds 
iodoform  in  small  quantities  is  indispensable. 

The  best  material  for  dressings  was  gauze  impregnated 
with  salicylic  acid  (five  to  ten  per  cent.)  or  corrosive 
sublimate  (i  part  per  1,000),  while  carbolized  gauze  was 
objectionable.  Wood-wool  cushions  are  of  advantage 
for  certain  wounds.  Dry  dressings  are  best  for  fresh,  as 
well  as  for  large  suppurating  wounds,  but  for  small  sup- 
purating wounds  moist  dressings  are  more  suitable.  In 
these,  however,  neither  carbolic  acid  nor  corrosive  subli- 
mate should  ever  be  used. 

In  order  to  prevent  soiling  of  the  dressings  with  urine 
he  favored  covering  them  with  a  waterproof  cloth,  the 


358 


THE  MEDICAL  RECORD. 


[September  27, 1884. 


edges  of  the  dressings  bein^  smeared  with  grease.  Other 
methods  of  avoiding  irritation  from  the  urine  were  verti- 
cal suspension  of  the  child,  frequent  changing  of  the 
dressings^  or  the  permanent  bath. 

In  concluding,  the  author  pointed  out  the  special  indi- 
cations for  the  employment  of  one  or  the  other  mode  of 
treatment  of  wounds  occurring  in  children. 

Professor  Jacobi,  of  New  York,  then  presented  a 
communication  on 

PRIMARY   SARCOMA   OF  THE    KIDNEY 

in  the  new-bom  and  in  the  young. 

This  was  followed  by  a  paper  of  Dr.  Sophus  Meyer, 
of  Copenhagen,  upon  the 

PROPHYLACTIC      TREATMENT     OF     OPHTHALMO-BLENNOR- 
RHCEA   NEONATORUM. 

Ophthalmia  neonatorum  is  an  essentially  dangerous 
affection,  and  measures  of  prophylaxis  are  therefore  of 
especial  importance.  We  do  not  yet  know  with  cer- 
tainty the  cause  of  the  disease,  and  we  ought  to  encour- 
age all  investigations  tending  to  elucidate  this  matter. 
Among  the  measures  employed  of  late  years,  that  of 
Cred6  may  be  considered  the  best.  It  is  certainly  a  very 
satisfactory  one,  as,  since  its  introduction  into  lying-in 
institutions  the  malady  has  almost  disappeared.  Credo's 
method  is  not  dangerous,  and  can  be  employed  by  mid- 
wives  just  as  well  as  by  physicians.  The  speaker  con- 
cluded by  urj'jng  upon  his  hearers  the  necessity  of  in- 
ducing midwives  generally  to  make  a  constant  use  of  the 
method  in  every  case. 

A  paper  was  then  read  by  Professors  Hirsch- 
sprung, of  Copenhagen,  and  Ribbing,  of  Lund,  on 

INTESTINAL   INVAGINATION. 

This  condition  was  treated  of  as  it  occurs  in  children, 
and  some  remarks  were  made  upon  its  comparative  fre- 
quence in  different  countries.  The  authors  endeavored 
to  show  that  the  great  difference  in  this  respect,  as  shown 
by  the  statistics  of  the  several  countries  mentioned,  was 
rather  apparent  than  real. 

Professor  Faye,  of  Stockholm,  followed  with  some 
remarks  on 

THE   TREATMENT   OF   SCOLIOSIS. 

At  the  conclusion  of  this  paper  the  session  adjourned. 


Saturday,  August  i6th — Sixth  Day. 

In  the  morning  a  joint  session  of  the  Sections  on 
Pediatrics  and  on  Hygiene  and  State  Medicine  was 
held. 

Two  highly  interesting  papers  were  read  by  Mr.  Mal- 
ling-Hansen,  of  Copenhagen,  and  Dr.  Vahl,  of  Jaegers- 
pris,  on  the 

normal  increase  of  WEIGHT  IN  ADVANCED  CHILDHOOD. 

The  observations  were  made  upon  girls,  from  four  to 
fifteen  years  of  age,  inmates  of  the  Jaegerspris  Asylum.' 
The  children  were  weighed  in  April  and  October  of  each 
year,  from  1874  to  1883.  It  was  found  that  the  normal 
weight  of  girls  at  this  age  increases  in  regular  progres- 
sion from  thirty-two  and  a  half  to  ninety-eight  and  a 
half  pounds  ^16.25  to  49.25  kilos).  Up  to  the  end  of 
the  fourteenth  year  the  annual  increment  is  eleven  per 
cent,  of  the  weight  of  the  previous  year,  but  after  this 
time  the  rate  of  increase  falls  off  somewhat.  The  in- 
crease during  the  six  warmer  months  is  greater  than  in 
the  six  colder  months,  in  the  proportion  of  four  to  three. 

At  the  afternoon  session  Professor  Medin,  of  Stock* 
holm,  read  a  paper  on  the 

TUBERCULAR  MENINGITIS   OF   EARLY   INFANCY. 

Tuberculosis,  the  speaker  maintained,  is  frequent  in  the 
new-born,  occurring  sometimes  in  very  severe  epidemics, 
but  tubercular  meningitis  is  rare.  Even  epidemic  cerebro- 
spinal meningitis  is  of  more  common  occurrence  in  young 


infants.  The  author  then  spoke  of  the  influence  of  age 
and  sex  and  of  the  seasons,  and  pointed  out  the  differ- 
ences in  the  symptoms  and  course  of  the  disease  as  it 
occurs  in  young  infants  and  in  children  of  a  more  ad- 
vanced age.  Tuberculosis  of  the  meninges  may  occur, 
he  said,  without  producing  meningitis,  and  in  such  cases 
there  are  no  symptoms  by  which  the  condition  can  be 
recognized.  The  paper  was  illustrated  with  a  number 
of  charts. 

Professor  Pr&vost  then  read  a  communication  from 
Professor  d'Espinb,  of  Geneva,  who  was  absent,  on 

A    RAPIDLY    CURABLE    FORM    OF    INFANTILE    SPINAL   PA- 
RALYSIS. 

At  the  conclusion  of  this  paper 

ADDRESSES 

were  made  to  the  Section  by  the  presidents,  Professor 
Rauchfuss,  of  St.  Petersburg,  in  French ;  Professor  Ja- 
cobi, of  New  York,  in  Enj;lish  ;  and  Professor  Hirsch- 
sprung, of  Copenhngen,  m  German. 

According  to  the   announcement  of  the  last-named 
speaker,  the  labors  of  the  Section  were  now  concluded. 


COMBINED    SECTIONS    OF    ANATOMY    AND  PHYSI- 
OLOGY. 

Tuesday,  August  i2TH — Second  Day. 
Professor  v.  Ebner  presented  a  communication  on 
behalf  of  Professor  Rollet,  on  the 

HISTOLOGY  OF  STRIATED   MUSCLE. 

The  author  of  the  paper  believed  that  the  primary  cle- 
ment in  the  muscular  fibre  is  the  fibrilla,  the  Cohnheini 
fields  being  a  section  of  a  number  of  these  fibrilla  with  an 
intermediate  substance.  This  intermediate  substance  not 
only  surrounds  the  fibrilla,  but  in  some  species  there  is  a 
layer  of  it  between  the  sarcolemma  and  the  fibrillar 
There  is  a  network  of  minute  fibres  which  embraces  the 
elements  of  which  Cohnheim's  fields  are  a  section.  The 
transverse  disks  are  produced  by  this  transverse  network 
under  the  influence  of  the  various  reagents.  The  varied 
appearances  observed  in  a  muscular  fibre  are  caused  by 
the  varying  relations  of  the  unformed  substance,  the 
fibrilla  and  this  network. 

In  the  discussion  which  followed  the  reading  of  this 
paper  Professors  Engelmann  and  Retzeus  stated  that 
they  agreed  with  the  author  on  the  main  points  in  the 
paper. 

Dr.  Thin  remarked  that  in  all  essential  points  the 
structure  of  striped  muscular  fibre,  as  described  by  the 
author  of  the  paper,  was  that  first  expounded  by  himself 
in  1874,  in  two  papers  published  respectively  in  the 
"  Proceedings  of  the  Royal  Society  "  and  the  Edinburgh 
Medical  Journal.  The  network  described  by  Rollet  in 
the  paper  just  read,  and  also  by  Retzius  in  his  mono- 
graph published  last  year,  is  the  same  as  that  described 
and  figured  by  himself  in  the  Edinburgh  Medical  Journal, 

Professor  Kronecker,  of  Berlin,  then  read  a  paper  on 

THE  CENTRE  OF  COORDINATION  FOR  THE   MOVEMENTS  OF 
THE  VENTRICLES   OF  THE   HEART. 

The  approximate  position  of  this  centre  in  the  dog  was, 
the  speaker  said,  about  one  centimetre  behind  the  de- 
scending branch  of  the  left  coronary  artery.  Injury  to 
this  centre  stopped  pulsation  at  once,  irregular  vibrations 
and  twitchings  silone  remaining.  By  a  series  of  experi- 
ments. Professor  Kronecker  has  ascertained  that  this 
centre  is  neither  inhibitory  nor  motor,  but  distinctly  co- 
ordinating. 

Dr.  Gaskell,  of  Cambridge,  read  a  paper  on 

INHIBITORY  ACTIONS   AND  THE   INHIBITORY   NERVES  IK 
GENERAL. 

After  referring  in  detail  to  the  present  views  on  inhib- 
itory and  excitor  impulses  in  single  nerve-trunks,  and  to 
Foster's  experiments  on  direct  inhibition  of  the  cardiac 


September  27,  1884.] 


THE  MEDICAL  RECORD, 


359 


muscle  of  the  snail,  Dr.  Gaskell  described  experiments  on 
portions  of  the  cardiac  muscle  of  the  tortoise,  upon  croc- 
odiles in  which  the  vagi  had  been  mutilated,  so  as  to  in- 
sure complete  degeneration  of  their  cardiac  periphery, 
and  upon  the  cardiac  nerves  of  frogs  in  which  the  vagus 
and  sympathetic  rami  were  completely  isolated.  Some 
recent  experiments  in  the  Cambridge  laboratory  were 
also  quoted  as  entirely  disposing  of  Foster's  experiment 
upon  the  snail's  heart.  Dr.  Gaskell's  experiments,  the 
record  of  which  in  the  shape  of  most  complete  polygraphic 
I  tracings  was  shown,  led  him  conclusively  to  state  that 
muscle  functions  are  not  inhibited  except  through  nerve 
stimuli.  As  to  the  condition  of  inhibited  tissues  or  or- 
gans, whether  the  state  is  one  of  death  or  of  increased 
potential  energy,  he  emphatically  expressed  his  opinion 
that  the  latter  was  the  actual  condition.  He  showed 
tracings  of  the  cardiac  contractions  during  stimulation  of 
the  sympathetic,  after  or  during  stimulation  of  the  vagus, 
which  supported  him  in  this  view. 


SECTION  ON  DERMATOLOGY  AND  SYPHILIS. 
THE   ETIOLOGY   OF   LUPUS. 

Professor  Doutrelkpont,  of  Bonn,  opened  the  discus- 
sion by  reading  a  paper  in  which  he  stated  his  belief  that 
lupus  is  really  a  tuberculosis  of  the  skin.  Not  only  are 
the  histological  characters  of  the  lupus  nodules  and  the 
miliary  tubercle  very  similar,  but  the  specific  bacillus  of 
tuberculosis  is  found  in  both.  The  clinical  course  of  the 
t^o  diseases  also  presents,  as  he  thought,  some  very 
marked  points  of  resemblance — the  slow  course,  for  ex- 
ample, of  some  cases  of  phthisis,  accompanied  with  many 
relapses.  But  the  most  important  and  most  direct  proof 
has  been  found  in  the  inoculation  of  small  pieces  of  lupus 
tissue  into  the  cornea  of  rabbits,  and  the  growth  of  dis- 
tinct tubercle  at  the  point  of  inoculation. 

Dr.  Lbloir,  of  Paris,  also  read  a  paper  dealing  with 
the  same  points,  and  quoted  a  case  of  undoubted  lupus 
of  the  bones,  in  which  the  disease  resembled  tuberculosis. 
He,  too,  had  inoculated  animals  with  lupus,  and  thereby 
produced  tuberculosis. 

Professor  Kaposi,  of  Vienna,  said  that  before  the 
bacteria  time  it  used  to  be  remarked  how  unusually  free 
from  tuberculosis  lupus  patients  were.  He  had  seen 
1,200  cases  of  lupus  in  twenty  years,  and  had  never  seen 
any  connection  between  the  two  diseases,  although  some 
patients  had  been  covered  with  the  lupus  for  many  years. 
Real  tuberculosis  of  the  skin,  of  which  he  had  seen  fifteen 
cases,  was  a  rare  and  entirely  different  disease,  in  which 
the  actual  miliary  tubercles  were  seen  plainly  on  the  most 
superficial  layers  of  the  skin,  and  it  was  always  rapidly 
&taL  Now,  however,  lupus,  which  is  a  perfectly  clear 
and  distinct  clinical  entity,  has  been  confused  with  tuber- 
culosis. 

Professor  Pick,  of  Prague,  had  long  been  led  to  sus- 
pect a  close  relationship  between  lupus  and  tuberculosis, 
but  could  not  establish  a  satisfactory  clinical  identity. 
The  discovery  of  giant  cells  at  first  promised  to  establish 
tiis  connection,  but  the  theory  of  their  specificity  was 
afterward  disproved.  The  discovery  of  the  bacillus  tuber- 
culosis had  had  a  more  satisfactory  result.  It  had  been 
jound  that  the  bacillus  was  always  present  in  abundance 
in  certain  stages  of  the  disease,  and  that  this  was  the 
case  even  where  no  tubercular  condition  of  other  organs 
was  present.  Observers  are,  however,  divided  as  to 
▼hether  the  bacillus  is  causal.  Professor  Pick  considers 
that  it  is,  and  thinks  that  tuberculosis  of  the  skin  may 
exist  as  lupus  vulgaris,  as  tuberculosis  cutis  of  Kaposi,  or 
in  many  other  possibly  not  yet  discovered  forms,  which 
may  differ  exceedingly,  just  as  syphilides  and  gummata 
differ  exceedingly,  and  which  it  may  take  a  long  time  to 
distinguish  and  classify,  as  was  the  case  with  lupus  and 
the  serpiginous  eruptions  of  syphilis.  Although  tuber- 
culosis cutis  is  not  lupus,  lupus  might  still  be,  and  proba 
bly  is,  a  tuberculosis. 

Professor  Neisser,  of  Breslau,  vigorously  opposed 


Kaposi,  the  value  of  whose  statistics  he  disputed,  since 
the  case  had  not  been  examined  with  a  view  to  settling 
this  question.  There  was  a  slow  and  a  galloping  syphilis, 
and  there  might  be  similar  conditions  in  tuberculosis  of 
the  skin.  He  considered  that  the  slow  course  and  fre- 
quent recurrences  in  lupus  were  very  like  the  course  and 
relapses  of  tuberculosis,  and  this  latter,  too,  like  lupus^ 
might  last  for  years.  Kaposi  seemed  to  simply  disbelieve 
in  the  bacillus  tuberculosis,  but  with  the  present  weight 
of  scientific  evidence  on  its  side,  Kaposi  certainly  would 
have  to  undertake  the  proof  that  lupus  was  not  a  tuber- 
culosis in  order  to  support  his  position. 

Dr.  Unna,  of  Hamburg,  agreed  with  Doutrelepont 
and  thinks  with  Pick  that  there  are  a  series  of  bacilloses 
of  the  skin,  all  containing  the  bacillus  tuberculosis.  He 
knows  of  four  such  affections  at  the  present  time,  viz., 
lupus  vulgaris,  tuberculosis  cutis  Kaposi,  lupus  papillaris 
Aubert,  and  scrofulous  eczema,  followed  by  caseous 
glands.  He  finds  the  bacilli  are  obtainable  in  quantity 
by  partially  digesting  hardened  specimens  and  examining 
the  precipitate  of  what  Has  fallen. 

Professor  Edward  Lange,  of  Innsbruck,  said  that  the 
murderous  disease  described  by  Kaposi  did  not  corre- 
spond to  ordinary  mild,  often  curable,  cases  of  tuber- 
culosis. There  was  probably  some  form  of  skin  tuber- 
culosis which  did  so  correspond,  just  as  there  were  cases 
of  carcinoma  which  were  rapidly  fatal,  and  cases  which 
dragged  on  for  decades. 

Dr.  Goldscheidbn  gave  an  interesting  address  on  the 

specific  sensibility  of  the  skin. 

He  strongly  supported  Helmholtz's  theory  that  every 
nerve,  however  excited,  gave  rise  to  only  one  specific 
perception  in  the  cerebral  ganglion  cell  with  which  it  was 
connected.  His  investigations  had  shown  him'  that  there 
were  only  certain  points  which  were  capable  of  feeling 
heat,  while  a  completely  different  and  complementary ^set 
perceived  only  cold.  It  was  immaterial  how  these  points 
were  excited,  whether  mechanically  or  by  temperature 
change  or  electrically,  the  effect  was  the  same ;  this  fact, 
of  course,  refuted  the  old  theory* of  perception  of  heat 
and  cold  by  simple  increase  or  decrease  of  the  amount 
of  heat  in  the  nerve.  These  temperature  nerves  when 
excited  give  rise  to  no  pain,  nor  do  they  possess  any 
sensibility.  Only  certain  "pressure  points"  possess 
acute  specific  sensibility,  and  outside  these  there  exists 
only  a  diffuse  indefinite  perception.  The  points  at  which 
pain  is  appreciated  are  sdso  quite  distinct  and  very  sen- 
sitive to  various  irritations.  These  pressure  and  pain 
points  are  always  complementary  to  the  points  at  which 
heat  and  cold  are  perceived*  The  touch  nerves,  like 
them,  are  always  arranged  in  areolae,  and  hence  the  ne- 
cessity of  passing  the  finger  over  any  body  which  we  are 
feeling,  until  an  areola  is  met  with  capable  of  appreciat- 
ing the  shape  and  surface  of  the  particular  body.  All 
these  functions  improve  notably  with  education,  as  seen 
especially  in  the  case  of  blind  people.  But  there  are 
many  areas  normally  destitute  of  all  appreciation  of  one 
or  more  of  these  different  modes  of  sensibility. 

Dr.  Armauer  Hansen,  of  Bergen,  spoke  at  length  on 
the  etiology  and  pathology  of  lepra.  He  exhibited  pa- 
tients to  show  the  difference  between  the  tubercular 
form  and  the  macular.  The  former  was  almost  always 
fatal  in  nine  or  ten  years,  and  the  latter  was  often  cured. 
The  anaesthesia  and  atrophy  which  follow  are  effects  of 
the  healing  process,  not  of  the  leprosy,  and  necrosis  of 
the  affected  parts  is  always  secondary  to  injury.  The 
paralyses,  too,  are  local ;  there  are  never  any  traces  of 
spinal  lesions  to  be  found  clinically  or  microscopically. 
He  insisted  that  lepra  was  not  an  hereditary,  but  a 
specific  contagious  disease ;  the  recurring  crops  of  nod- 
ules showed  its  anti-inoculability,  and  since  the  growths 
tend  to  heal,  it  must  be  specific.  There  is,  moreover, 
no  anatomical  correlation  between  the  parts  affected  as 
in  the  metastasis  of  neoplasms.  The  cause  of  the  dis- 
ease had  long  been  obscure.     Years  ago  he  had  noticed 


36o 


THE   MEDICAL   RECORD. 


[September  27,  1884. 


peculiar  brown  cells,  which  were  always  present  in  mi- 
croscopic sections  of  lepra.  In  1871  he  described  mi- 
nute moving  rods  in  the  contents  of  a  breaking  down 
tubercle,  and  immediately  after  Koch's  discovery  he 
found  the  bacillus  leprae  by  applying  the  same  methods. 
He  had  never  found  them  in  anaesthetic  patches,  but 
Ahning  has  found  them  in  anaesthetic  nerves.  The 
speaker  and  Professor  Neisser  have  both  cultivated  them. 
Inoculation  on  rabbits  and  cats  (Hansen),  and  on  fish 
(Kobner  and  Hansen)  had  been  unsuccessful,  but  Neis- 
ser had  produced  a  new  growth  by  inoculating  a  dog. 
No  animal  has,  however,  been  lepraized  as  yet.  He 
does  not  believe  in  the  heredity  of  a  contagious  disease  ; 
a  disease  may  be  congenital  without  being  hereditary, 
for  example,  small-pox.  Heredity  and  the  transmission 
of  such  a  disease  as  syphilis  are  entii^ly  different  mat- 
ters ;  the  latter  may  develop  late,  and  is  incapable  of 
atavism,  etc.  Relationship,  even,  with  leprous  people, 
is  by  no  means  always  present.  The  inhabitants  of  a 
valley  become  in  time  all  more  or  less  related,  and  the 
members  of  one  family  naturalfy  come  into  closer  con- 
tact with  each  other  than  with  outsiders,  hence  the 
apparent  frequency  of  the  spread  among  relations.  Isola- 
tion is  necessary,  for  although  the  disease  is  spontane- 
ously curable,  we  cannot  cure  it ;  but  the  effect  of  isola- 
ting the  cases  in  Norway  has  been  effective  in  reducing 
the  number  of  lepers  by  nearly  one-half  in  twenty 
years. 

Professor  Neisser  agreed  in  Hansen's  views  as  to 
contagiousness  and  heredity  in  lepra.  The  spores  which 
Dr.  Hansen  had  spoken  of  were  probably  vacuoles. 

Professor  Pick  read  a  paper  on 

EXCISION   OF  THE   INITIAL   SCLEROSIS    IN    SYPHILIS. 

He  confined  his  remarks  to  hard  chancres,  and  dis- 
tinguished carefully  between  those  cases  in  which  the 
glands  were  indurated  and  those  in  which  they  were  not. 
Where  the  glands  are  affected  they  must  also  be  excised, 
but  in  such  cases,  almost  without  exception,  whether  ex- 
cision is  practised  or  not,  general  symptoms  make  their 
appearance.  The  conditions  under  which  the  operation 
may  be  performed  are  only  partially  known.  Simple 
excision  of  the  sclerosis  where  the  glands  are  affected 
will  never  give  success,  and  no  excision  avails  when 
the  deep  glands  are  swollen.  Pick  considers  the  ef- 
fect on  the  therapeutics  is  but  slight,  mostly  only  a 
delay  in  the  appearance  of  the  general  symptoms. 
The  operation  has,  however,  served  to  show  that  the 
indurated  sclerosis  is  not  the  expression  of  general 
syphilis.  The  lymphatics  have  recently  been  found  to 
be  much  enlarged  in  these  cases,  and  Pick  believes 
that  the  syphilitic  poison  passes  into  the  organism 
through  these,  and  not  as  Auspitz  believes,  entirely 
through  the  blood. 

Dr.  Unna,  of  Hamburg,  believes  that  syphilis  spreads 
not  by  any  one  path,  but  by  botn  the  blood-vessels, 
lymph-vessels,  and  by  simple  contiguity  of  tissue. 

Professor  Neisser,  of  Breslau,  observed  that  al- 
though it  was  not  yet  certain  by  what  path  the  syphilitic 
virus  entered  the  system,  still  since  it  was  a  bacterial 
virus,  there  was  no  theoretical  reason  why  it  should  not 
be  prevented  from  entering  by  timely  destruction  of  the 
bacteria. 

Professor  Bergh,  of  Copenhagen,  gave  accurate 
statistics  extending  over  some  years,  and  showing  the 
comparative  worthlessness  of  the  operation  as  a  protec- 
tive measure. 

Drs.  Leloir  and  Barthelemy,  of  Paris,  quoted  most 
favorable  cases  in  which  excision,  a  few  hours  after  the 
first  appearance  of  the  chancre,  failed  to  prevent  infec- 
tion, and  the  latter  stated  that  French  opinion  was  now 
decidedly  opposed  to  the  procedure. 

Dr.  Martineau,  of  Paris,  in  opposition  to  the  Ger- 
man speakers,  regarded  the  chancre  as  a  manifestation 
of  general  infection,  and  considered  it,  therefore,  to  be 
manifestly  u.»eless  to  excise  it. 


Professor  Liebrsich,  of  Berlin,  in  a  paper  on 

THE   TREATMENT  OF  SYPHILIS  BY  MERCURIAL  INJECTIONS, 

said  he  found  that  certain  conditions  were  requisite  in 
any  mercurial  compound  which  was  to  be  subcutaneously 
injected,  viz.,  it  must  not  precipitate  albumen,  must  be 
indifferent  to  the  connective  tissue  of  the  skin,  must  not 
be  decomposed  by  an  alkaline  solution,  must  be  easily 
broken  up,  so  that  with  sulphur  sulphide  of  mercury  is 
precipitated.  Corrosive  sublimate  forms  insoluble  com- 
pounds with  albumen,  and  wnich  is  only  absorbed  when 
these  are  broken  up ;  it,  moreover,  breaks  all  the  other 
conditions  except  the  last.  Tannates  and  citrates  of 
mercury  also  unite  with  albumen  and  reach  the  blood  in 
complicated  combinations.  A  body  which  fulfils  all  these 
conditions  is  found  in  the  formamide  of  mercury,  which 
is  easily  prepared  by  precipitating  the  oxide  by  carbon- 
afe  of  ammonia  and  dissolving  it  in  formamide.  Amides 
of  a  number  of  other  fatty  acids  also  work  well.  If  in- 
jected in  quantity  they  form  sloughs  in  the  bowels  during 
elimination  (as  does  the  sublimate)  showing  that  they 
can  work  efficiently,  the  mercury  in  the  compound  being 
simply  masked  by  the  amide.  They  cause  neither  pain 
nor  irritation  of  the  tissues,  and  the  dose  is  somewhat 
less  than  that  of  sublimate.  It  is,  above  all,  ini|>ortant 
that  the  course  of  injections  nmst  be  several  times  re- 
peated ;  it  is  impossible  to  be  sure  of  curing  by  one 
course  alone.  In  the  midst  of  the  injections  the 
case  sometimes  ceases  to  improve  ;  the  original  vigor, 
however,  can  be  rapidly  restored  by  giving  a  good 
diet,  with  plenty  of  chloride  of  sodium,  this  salt  and 
chloride  of  ammonium  both  assisting  powerfully  as 
"help  cures." 

Dr.  Martineau  said  he  had  used  injections  exclu- 
sively in  the  treatment  of  syphilis  for  the  last  few  years, 
and  believed  that  it  was  the  only  reliable  method,  assur- 
ing  a  cure  and  causing  no  stomatitis  or  other  alimentary 
troubles.  In  no  case  was  the  disease  itself  cured,  but 
merely  the  manifestations,  and  in  doing  this,  mercury  in- 
jected subcutaneously  occupied  less  than  half  the  time 
required  by  the  other  methods. 

There  was  a  general  consensus  of  opinion  among  the 
after  speakers  that  the  injection  of  mercurials  was  a  valu- 
able method  of  treating  syphilis,  but  by  no  means  the 
only  one.  No  one  method  suited  all  cases.  Mcisser 
thought  that  the  injections  should  be  smaller  and  more 
frequent,  and  considered  that  the  formamides  eliminated 
too  quickly. 

Professor  Doutrelepont  said  he  does  not  believe 
formamide  to  be  absolutely  the  best  form  for  injection. 
All  salts  when  injected  in  a  sufficient  therapeutic  dose, 
may  cause  stomatitis. 

Dr.  Shoemaker,  of  Philadelphia,  after  prolonged  ex- 
periments on  the  various  methods  of  injecting  mercury, 
had  come  back  to  the  simple  solution  of  sublimate  in 
water,  as  the  most  effectual  and  least  irritating. 

Dr.  Wulff,  of  Strasburg,  had  made  and  injected  the 
formamides  five  years  ago.  He  always  used  them  per- 
fectly freshly  made  from  triturated  solutions  ;  they  then 
work  quickly  and  well. 

Dr.  Unna  advocated  the  use  of  keratinized  mercurial 
pills,  which  dissolve  in  the  alkaline  juices  of  the  small 
intestine,  leaving  the  stomach  untouched  ;  in  this  way 
the  irritation  caused  by  injection  may  be  avoided. 

Dr.  Barthelemy  always  used  the  peptones  for  injec- 
tion and  found  that  they  acted  quickly,  but  believed  that 
pills  were  by  far  the  best  and  simplest  method  for  con- 
tinued treatment. 

Professor  Kaposi  found  injections  useful,  but  con- 
sidered that  inunction  was  by  far  the  quickest  and  most 
vigorous  method  of  cure. 

Most  of  the  speakers  considered  that  although  statis- 
tics were  a  valuable  help  in  deciding  the  relative  merits 
of  the  different  methods  of  cure,  especially  the  statistics 
of  venereal  hospitals  for  prostitutes,  yet  the  judgment  of 
the  relative  merits  of  different  methods  depended  mostly 


September  27,  1884.] 


THE  MEDICAL  RECORD, 


361 


on  the  good  clinical  observation  of  the  individual  experi- 
menter. 

INOCULATION   OF  SYPHILIS   IN   ANIMALS. 

Dr.  Martineau  had  successfully  inoculated  a  monkey 
with  syphilis  and  produced  a  distinct  chanae,  erosive  and 
ulcerative  syphilides  of  the  skin  and  pharynx,  and  hyper- 
trophic papular  syphilides  of  the  scrotum  and  thigh. 

Professor  Pick  had  seen  the  monkey  which  Klebs 
claimed  to  have  syphilized.  He  was  only  acquainted 
wiJh  syphilis  in  the  human  subject,  but  the  eruption 
which  broke  out  in  the  monkey  looked  to  him  more  like 
a  varicella  accidentally  inoculated,  than  like  any  syphi- 
litic eruption  m  man. 


PRACriTlONERS'  SOCIETY   OF   NEW  YORK. 

Stated  Meetings  June  6,   1884. 

Samlel  Sexton,  M.D.,  President, /r^  tern. 

Dr.  VVm.  T.   Lusk  read  the  paper  of  the  evening,  en- 
titled: 

sudden  death   in  childbirth. 

The  case  illustrating  such  had  the  following  history: 
The  patient  was  a  pritnipara,  healthy,  and  twenty-three 
years  of  age.  I  first  saw  her  January  ist  of  present  year 
at  7  A.M.  Patient  said  pains  had  begun  on  previous  af- 
ternoon, and  she  had  paced  the  floor  all  night  She  said 
that  when  in  mo  lion  she  found  it  easier  to  bear  her  pains. 
Examination  :  Extreme  tenderness  of  vagina  and  cervix ; 
cervical  canal  dilated  by  head,  os  extended,  size  of  half 
dollar  \  head  covered  tightly  by  membranes,  no  pouch« 
At  II  o'clock  little  progress.  Gave  chloroform  and 
pushed  up  head  so  as  to  allow  bag  of  waters  to  form. 
This  manoeuvre  was  followed  by  rapid  dilatation.  Head 
in  twenty  minutes  on  perineal  floor.  1  then  urged 
forceps.  Patient  wished  •*  glory  of  having  her  baby  her- 
self." Waited  at  her  instance  until  between  i  and  2 
0  clock.  Patient  suddenly  lost  color  and  seemed  dazed 
when  spoken  to.  Applied  forceps  to  head  at  vulva. 
Easy  extraction  followed  by  some  hemorrhage,  but  the 
latter  was  quickly  controlled.  Patient's  face  showed 
signs  of  complete  collapse.  Stimulants,  warm  hypoder- 
mics of  brandy,  and  hot  tea  were  given  at  short  intervals. 
Apparent  rally.  At  7  p.m.  went  to  dinner,  thinking 
period  of  safety  reached.  Patient  suddenly  turned  in 
bed,  and  pulse  became  very  feeble.  There  was  a  slight 
rally,  and  then  came  death.  Absence  of  respiratory 
troubles  excluded  pulmonary  embolism  either  from  ve- 
nous thrombi  or  from  air.  The  associated  symptoms  were 
those  of  surgical  shock,  to  which  the  patient  was  prob- 
ably predisposed  by  the  ante-partum  exhaustion.  The 
writer  argued  against  the  rejection  of  surgical  shock 
among  the  causes  of  sudden  death  in  childbed,  holding 
that  the  entry  of  air  into  veins,  embolism,  and  pulmonary 
thrombosis  are  insufficient  to  account  for  all  cases. 

Dr.  G.  F.  Shrady  mentioned  two  cases  which  had 
just  been  published  in  The  Medical  Record,  and  in 
which  death,  as  he  thought  Dr.  Lusk  would  agree,  was 
due  probably  to  shock.  He  had  seen  in  journals  the 
reports  of  two  other  cases  within  the  last  six  months. 

Dr.  Lusic  remarked  that  text-books  on  obstetrics  as- 
sumed that  it  was  not  possible  for  a  woman  to  die  of 
shock  in  parturition,  but  from  what  he  had  observed,  he 
was  inclined  to  believe  that  death  in  lying-in  women  was 
not  infre(^uently  produced  by  that  cause. 

Dr.  Shrady  thought  that  death  in  Dr.  Lusk's  case 
was  best  explained  on  the  supposition  that  it  was  pro- 
duced by  shock ;  for  the  phenomena  were  exactly  what 
occurred  in  surgical  practice  from  sudden  loss  of  blood 
in  a  nervous  patient. 
Dr.  Dana  asked  if  the  patient's  heart  was  examined. 
Dr.  Lusk  said  he  examined  the  heart  and  did  not  find 
any  sounds  to  indicate  the  presence  of  cardiac  disease, 
and  the  patient  was  so  young  and  had  enjoyed  such 


perfect  health  that  he  thought  any  change  afifecting  the 
muscular  structure  of  the  heart  could  be  reasonably  ex- 
cluded. 

Dr.  Dana  asked  if  any  pathological  evidence  had 
been  obtained  to  sustain  the  view  that  shock  was  due  to 
paralysis  of  the  splanchnic  nerves. 

Dr.  Lusk  replied  that  the  view  was  the  result  of  ex- 
periments on  animals. 

Dr.  Dana  thought  that  experiments  on  animals  proved 
just  the  opposite,  because  when  these  nerves  were  com- 
pletely divided,  causing  paralysis  of  the  blood-vessels 
supplying  these  viscera,  the  animals  do  not  die. 

Dr.  Lusk  said  the  experiments  were  performed  by 
striking  upon  the  abdominal  walls,  producing  paralysis  of 
the  blood-vessels  and  withdrawal  of  blood  from  the  heart. 

Dr.  Dana  remarked  that  striking  the  abdomen,  espe- 
cially when  the  peritoneum  was  inflamed,  might  stop  the 
heart,  but  it  did  so  by  affecting  certain  sensory  nerves. 

Dr.  Ball  asked  if  the  eflect  was  not  too  sudden  to 
account  for  it  upon  the  supposition  of  withdrawal  of 
blood  from  the  heart. 

Dr.  Lusk  remarked  that  he  did  not  feel  called  upon  to 
defend  the  theory  of  the  production  of  shock,  but  in  the 
most  recent  articles  on  shock  the  theory  of  Fisher  was 
that  which  had  been  adopted,  and  to  him  shock  as  a 
cause  of  death  in  the  cases  under  consideration  seemed 
to  be  the  most  reasonable  explanation  which  had  been 
offered. 

Dr.  Dana  asked  further  if  it  was  not  a  clinical  fact 
that  death  had  occurred  with  chloroform  some  time  after 
the  anaesthetic  had  been  removed. 

Dr  Lusk  said  that  such  cases  had  been  reported,  but 
he  was  not  aware  that  any  had  been  reported  in  which 
death  occurred  after  the  patient  had  regained  com- 
plete consciousness,  and  during  the  administration 
showed  no  undue  sensitiveness  to*tlthe  anaesthetic.  It 
had  been  suggested  by  Dr.  Delafleld  that  this  was  the 
explanation  of  sudden  death  in  these  cases,  but  on  look- 
ing over  the  literature  of  the  subject.  Dr.  Lusk  had  found 
that  the  cases  occurred  so  much  more  frequently  before 
chloroform  was  introduced  into  obstetric  practice  than 
they  had  since  that  the  fact  seemed  to  disprove  the  sup- 
position that  death  was  due  to  chloroform. 

In  Dr.  Lusk*s  case  there  was  an  interval  of  two  hours 
between  the  first  and  second  administration,  and  during 
this  interval  the  woman  was  perfectly  conscious  and  gave 
no  evidence  that  she  had  been  unduly  afifected  by  the 
chloroform  ;  at  tlie  first  it  was  administered  in  moderate 
quantities  for  half  an  hour,  and  at  the  second  adminis- 
tration it  was  given  for  fifteen  minutes. 

Dr.  E.  L.  Partridge  alluded  to  two  cases  of  sudden 
death  following  labor.  One  was  a  case  in  which  the 
woman  died  suddenly  on  the  twelfth  day  after  confine- 
ment without  any  unfavorable  symptoms  during  the  pu- 
erperal period,  except  a  moderate  cellulitis,  from  which 
she  recovered  promptly,  all  the  symptoms  disappearing, 
and  the  pulse  and  temperature  becoming  normal.  One 
morning,  while  the  nurse  and  physician  were  standing 
at  the  bedside,  just  after  the  pulse  had  been  noted  at  88 
and  the  temperature  99^  F.,  the  patient  asked  for  a 
drink  of  water  in  the  usual  way,  and  within  ten  minutes 
was  dead,  without  a  symptom  or  movement.  The  pulse 
continued  to  beat  two  or  three  moments  after  respiration 
ceased. 

The  autopsy  revealed  an  abscess  of  the  cerebellum. 
The  patient  had  had  ear  trouble,  without  discharge  or 
anything  to  direct  attention  to  it  during  her  stay  in  the 
hospital  (Nursery  and  Child's).  It  was  not  supposed  that 
parturition  had  anything  to  do  with  the  abscess  m  the 
cerebellum.  But  the  case  was  interesting  as  an  illus- 
tration of  the  fact  that  parturient  women  can  die  from 
causes  other  than  those  connected  with  the  process  of 
labor. 

In  the  other  case,  the  woman  died  of  shock  and  ner- 
vous prostration  following  tedious  labor.  The  forceps 
were  applied  early ;  there  was  no  hemorrhage,  but  the 


362 


THE  MEDICAL  RECORD. 


[September  27,  1884. 


woman  died  within  twenty-four  hours.  At  the  autopsy 
nothing  was  found  to  explain  the  sudden  death. 

In  absence  of  post-mortem  examination  he  would 
not  be  willing  to  say  that  death  in  Dr.  Lusk's  case  was 
due  to  shock ;  and  at  the  same  time  he  did  not  feel  will- 
ing to  say  that  she  did  not  die  of  shock. 

Dr.  Lusk  said  he  assumed  that  a  woman  who  took  no 
rest  for  the  length  of  time  his  patient  abstained  from  it 
must  necessarily  place  herself  in  an  unfavorable  condi- 
tion, and  he  had  believed  that  such  symptoms  were  due 
to  exhaustion. 

Dr.  a.  a.  Smith  narrated  a  case  as  follows :  In  the 
year  1873  he  was  asked  to  attend  a  young  woman  in 
confinement.  He  promised  to  visit  her  on  a  Tuesday. 
The  mother  sent  for  him  on  Monday  afternoon,  and 
when  he  arrived  he  heard  the  following  history :  On 
Saturday  afternoon  the  patient  reached  up  to  pull  the 
window  down,  and,  'as  she  did  so,  she  felt  something 
give  way,  and  was  seized  at  once  with  sharp  pain  in  the 
lower  part  of  the  abdomen.  She  sat  down  in  a  chair  for 
a  short  time,  but,  not  feeling  very  well,  went  to  bed.  On 
the  following  day  she  felt  tolerably  well,  but  on  Monday 
Dr.  Smith  was  sent  for  on  account  of  sharp  pain  and 
quite  free  hemorrhage.  Vaginal  examination  revealed 
the  fact  that  labor  had  begun,  and  the  case  progressed 
very  well  up  to  three  hours  afterward,  when  the  woman 
be^an  to  complain  of  feeling  weak,  and,  although  the 
child's  head  was  quite  well  down  in  the  pelvis,  there 
seemed  to  be  a  tumor  of  considerable  size  above.  He 
was  unable  to  obtain  sufficient  evidence  to  make  it  cer- 
tain that  there  was  internal  hemorrhage,  but  delivered 
the  woman  at  once  of  a  child  weighing  six  and  a-half 
pounds,  and  with  the  delivery  there  was  rise  of  pulse 
and  evidence  of  hemorrhage,  as  shown  by  one  great 
gush  of  blood  with  the  delivery  of  the  child.  No  further 
hemorrhage  occurred,  but  the  woman  died  within  an 
hour  after  the  birth  of  the  child,  as  the  result  of  ex- 
haustion and  shock  caused  by  antepartum  loss  of  blood. 
Dr.  Smith  believed  that  if  he  could  have  diagnosticated 
ante-partum  hemorrhage  he  could  have  saved  the  pa- 
tient's life  by  the  h)(podermic  injections  of  ergot  and 
atropia,  etc. 

SUCCESSFUL  OPERATION    FOR    EXSTROVERSIGN   OF  THE 
BLADDER. 

Dr.  George  F.  Shrady  presented  a  cMagram  which 
illustrated  the  successive  steps  in  an  operation  he  had 
performed  at  the  Presbyterian  Hospital,  in  a  case  of  ex- 
stroversion  of  the  bladder. 

The  patient  was  a  male,  five  months  old.  A  triangu- 
lar skin-flap  with  its  apex  just  below  the  umbilicus  was 
dissected  downward  to  the  upper  surface  of  the  exposed 
posterior  wall  of  the  bladder  and  turned  downward  like 
the  leaf  of  a  book,  the  base  of  the  flap  being  left  attached. 
By  this  means  the  exstroversion  was  completely  covered, 
leaving  two  raw  triangular  surfaces  exposed  with  a  com- 
mon base.  One  of  these  surfaces  was  the  bed  of  the  flap, 
and  the  other  the  posterior  surface  of  reversed  flap  it- 
self. To  cover  the  raw  ^surface  of  the  reversed  flap  a 
quadrilateral  flap,  looking  downward  and  inward,  includ- 
ing skin  from  the  lower  portion  of  abdomen,  groin,  and 
sides  of  the  scrotum,  was  made  on  either  side  and  turned 
inward  so  that  the  lower  and  free  extremities  of  each 
could  be  joined  in  the  median  line.  The  triangular  raw 
surface  of  the  bed  of  the  reversed  flap  above  was  con- 
verted into  an  inverted  T-shaped  wound  by  loosening 
the  basal  angles  of  the  raw  surface  and  joining  them  in 
the  median  line.  The  beds  of  the  quadrilateral  flaps 
in  the  groin,  which  were  triangular  in  shape,  were  also 
converted  into  T-shaped  wounds  by  carefully  sliding  the 
opposing  edges  toward  each  other. 

The  reversed  flap  was  first  sewed  in  position,  com- 
pletely covering  in  the  bladder,  one  thread  of  each  suture 
being  left  long  so  as  to  be  brought  out  externally  from 
between  the  edges  of  the  superimposed  flaps.  The 
quadrilateral  flaps  were  then  sewed  in  place,  and  then 


the  upper  raw  surfaces  and  the  beds  of  the  quadrilateral 
flaps  were  closed  as  indicated. 

The  wounds  healed  by  first  intention,  except  at  one 
unimportant  point,  which  subsequently  closed  by  granu- 
lation, and  the  child  made  a  perfect  recovery,  tiiie  urine 
escaping  only  by  a  small  opening  over  the  pubes. 

A  condition  of  epispadias  existed,  which  Dr.  Shrady 
intended  to  remedy  by  subsequent  operations  when  the 
child  was  old  enough  to  warrant  them.' 

EXTRA-UTERINE   PREGNANCY. 

Dr.  Charles  S.  Ward  presented  the  child  and  pla- 
centa  removed  by  operation  in  a  case  of  extra-uterine 

pregnancy,  with    the    following    history.     Mrs.  B -, 

twenty-three  years  of  age,  the  mother  of  one  child,  and 
no  miscarriages.  Her  child  was  bom  four  years  ago, 
and  the  labor  was  normal.  Her  menstrual  history  was 
normal  until  last  July,  when  a  slight  show  became  con- 
stant until  lately.  She  first  noticed  enlargement  of  her 
abdomen  in  August  last.  The  abdomen  gradually  in- 
creased in  size,  and  movements  were  tfirst  noticed  in 
September,  and  ceased  in  March  last.  The  woman 
thought  she  was  at  full  term  in  March.  During  the  last 
three  months  she  had  had  aching  in  the  pelvis.  The 
mammary  signs  were  normal  until  last  March.  During 
the  last  three  weeks  she  has  lost  flesh.  Dr.  Thomas 
diagnosticated  abdominal  pregnancy  when  he  saw  the 
woman  in  March.  He  performed  laparotomy  June  5th, 
and  removed  the  foetus  with  a  part  of  the  placenta. 
The  abdomen  presented  the  appearance  of  that  of  a 
woman  in  the  seventh  month  of  pregnancy.  On  palpa- 
tion, an  elastic  tumor  could  be  felt,  and  per  vaginam  the 
uterus  could  be  recognized  as  anteverted,  somewhat 
enlarged,  with  a  cervix  normal  to  the  touch,  and  ballotte- 
ment  was  absent.  Neither  was  there  any  body  to  be 
detected,  except  by  the  fact  that  something  filled  the 
superior  strait  of  the  pelvis.  Up  to  three  months  ago 
the  woman  believed  that  she  was  pregnant.  Except  for 
the  extreme  degree  of  pigmentation  of  the  abdommal 
walls,  Dr.  Ward  would  have  felt  sure  that  extra-uterine 
pregnancy  did  not  exist. 

On  making  an  incision  through  the  abdominal  walls  in 
the  median  hne,  he  reached'  first  a  brownish-black  look- 
ing body,  which  presented  very  much  the  appearance  of 
the  liver.  After  opening  the  membrane  about  a  quart  of 
fluid,  resembling  molasses  and  water  poured  out,  and  in 
passing  his  hand  in  Dr.  Thomas  was  able  to  seize  a  leg 
and  delivered  a  child  weighing  nine  pounds.  It  was  the 
sixth  case  which  Dr.  Ward  had  seen  operated  on,  and 
the  next  step  of  special  interest  pertained  to  the  manage- 
ment of  the  placenta,  which  presented  the  appearance  of 
a  cup  covering  the  entire  anterior  surface  of  the  growth, 
and  looking  very  much  like  the  liver,  both  in  color  and 
contour,  and  giving  very  much  the  feel  of  the  liver.  It 
was  attached  to  the  ileo-pectineal  line  on  the  right  side, 
extended  upward  under  the  diaphragm,  und  dipped  down 
into  the  pelvis  on  the  left  side.  The  placenta  was  par- 
tially removed  by  tying  it  off  in  sections  from  its  attach- 
ment to  the  pelvic  rim,  omentum,  and  intestines,  and 
this  was  accomplished  with  comparatively  a  small  amount 
of  hemorrhage. 

The  question  concerning  the  advisability  of  leaving  the 
after-birth  was  raised.  In  some  of  the  cases  it  had  been 
allowed  to  remain  and  to  discharge  from  the  opening  in 
the  abdominal  wall ;  but  it  was  probable  that  such  a  mass, 
weighing  several  pounds,  could  not  be  discharge^,  and  it 
was  determined  to  remove  a  portion  of  it  at  least,  if  it 
could  be  detached  from  the  intestines  and  omentum  so 
as.to  avoid  hemorrhage,  as  the  |^art  attached  to  the  pelvic 
brim  could  be  secured  so  as  to  avoid  special  danger 
from  that  source.  The  remaining  portion  of  the  pla- 
centa was  sewed  to  the  abdominal  wound,  and  an  open- 


>  The  child  continued  to  do  well  for  two  months  after  the  operation,  and  was 
altogether  in  a  very  satisfactorjr  condition,  when  during  the  heated  term  of  die 
present  summer  it  was  seized  with  cholera  infantum,  dying  of  the  disease  to  one 
week.    No.auiopsy  was  obtainable. 


September  27,  1884.] 


XHE  MEDICAL  RECORD. 


363 


ing  left  for  drainage.     Thus  far  the  patient  was  doing 

well.  .  .        ,. 

Dr.  Lusk  had  a  case,  a  short  tune  ago,  m  which 
diagnosis  was  very  puzzling.  The  patient  came  to  him 
with  a  note  from  her  physician,  who  said  that  she  was 
uDinistakably  pregnant,  but  that  all  the  symptoms  had 
disappeared.  Dr.  Lusk  found  that  there  were  no  special 
symptoms  of  pregnancy,  and  the  patient  soon  afterward 
left  the  hospital.  She  returned  two  months  ago,  when  it 
was  found  that  the  tumor  had  increased  in  size.  Dr. 
Lusk  then  introduced  a  needle  and  withdrew  considera- 
ble pus.  He  then  regarded  the  case  as  one  of  pyo- 
salpinx,  and  proceeded  to  operate.  After  exposing  the 
mass  and  tying  ofif  the  omentum,  he  endeavored  to  de- 
tach the  tumor,  which  was  embedded  in  the  pelvis  and 
extended  between  the  bladder  and  the  rectum,  and  on 
lifting  it  up  and  working  his  fingers  down  by  its  side  they 
passed  directly  into  the  rectum.  He  soon  found  that  it 
would  be  impossible  to  enucleate  the  mass,  and  there- 
fore cut  into  it,  when  he  found  a  very  marked  thicken- 
ing of  the  decidua,  and  inferred  that  it  was  a  case  of 
tubo-ovarian  pregnancy,  although  he  was  unable  to  find 
any  trace  of  the  embryo.  He  then  emptied  the  sac, 
stitched  its  walls  and  the  peritoneal  growth  to  the  edges 
of  the  abdominal  wound,  and  the  patient  did  very  well. 
The  sac  gradually  closed,  the  wound  had  been  reduced 
to  small  size,  and  the  patient  was  sitting  up  in  the  ward. 

The  Society  then  adjourned. 


MEDICAL    SOCIETY    OF    THE    COUNTY    OF 
iNEW  YORK.  . 

^Stated  Meetings  September  22,  1884. 

David  Webster,  M.D.,  President  pro  tern, 

CANDIDATES    FOR   MEMBERSHIP. 

The  Comitia  Minora  recommended  for  membership 
Dis.  A.  K.  Hills  and  A.  T.  Hills,  graduates  of  Homoeo- 
pathic Medical  Colleges.  On  motion  the  recommenda- 
tion was  referred  back  to  the  Comitia  for  further  investi- 
gation. 

NOMINATION   OF   OFFICERS. 

The  following  nominations  were  made  for  officers  for 
the  ensuing  year  : 

For  President — Drs.  Daniel  Lewis,  Henry  B.  Sands, 
D.  B.  St.  John  Roosa,  and  Andrew  H.  Smith. 

For  Vice-President — Drs.  Frank  P.  Foster  and  Lau- 
rence Johnson. 

For  Secretary — Dr.  Wesley  M.  Carpenter; 

For  Assistant  Secretary — Dr.  Charles  H.  Avery. 

For  Treasurer — Dr.  Orlando  B.  Douglas. 

For  Censors— Drs.  J.  W.  Howe,  F.  R.  S.  Drake,  W. 
0.  Moore,  ¥.  M.  Weld,  A.  S.  Hunter,  H.  E.  Crampton, 
a  T.  Peirce,  J.  H.  Ripley,  and  W.  R.  Gillette. 

Dr.  a.  Jacobi  then  read  a  paper  on 

LXFECnOUS    DISEASES    IN    THE    CHILDREN'S     SERVICE    OF 
BELLEVUE    HOSPITAL, 

and  directed  special  attention  to  typhoid  fever  and  diph- 
theria. It  will  appear  in  a  subsequent  number  of  The 
Record. 

The  paper  was  discussed  by  Drs.  G.  B.  Fowler,  C.  H. 
Knight,  M.  B.  Feeney,  E.  H.  M.  Sell,  A.  Seibert ,  and 
the  discussion  was  closed  by  Dr.  Jacobi. 

Dr.  R.  Van  Santvoord,  Secretary,  read  a  report 
from  the  Committee  on  Hygiene  on 

THE  free  baths  OF  THE  CITY  OF  NEW  YORK, 

in  which  attention  was  directed  to  their  usefulness  and 
the  urgent  necessity  for  a  greater  number  was  pointed 
oat 

The  report  was  accepted  and  its  recommendations 
adopted. 


PROPOSED   AMENDMENTS   TO   THE   BY-LAWS. 

Any  member  neglecting  to  pay  dues  and  assessments 
for  two  years,  shall  forfeit  his  or  her  membership,  pro- 
vided he  or  she  shall  have  received  from  the  Treasurer 
one  month's  notice  of  his  or  her  delinquency.  Such 
member  may  be  reinstated  upon  the  recommendation  of 
the  Comitia  Minora  after  the  payment  of  his  or  her 
arrears. 

Stated  meetings  shall  be  held  on  the  fourth  Monday  of 
every  month,  except  in  the  months  of  June,  July,  Au- 
gust, and  October  (annual  meeting). 

Dr.  John  L.  Vandevoort  was  nominated  for  honor- 
ary membership. 

abuse  OF  medical  charity. 

The  Secretary  read  a  communication  received  from 
Dr.  W.  H.  Donaldson,  Secretary  of  the  Bridgeport 
Medical  Society  and  of  the  Fairfield  County  Medical 
Society,  Connecticut,  directing  attention  to  the  fact  that 
many  persons  who  were  abundantly  able  to  pay  phy- 
sicians' fees  came  from  that  locality  to  New  York  and 
obtained  gratuitous  medical  advice  at  hospitals  and  dis- 
pensaries in  the  city  of  New  York. 

The  communication  was  received  and  referred  to  a 
committe  of  three,  Dr.  A.  Jacobi,  Chairman,  to  be  re- 
ported on  at  some  future  meeting. 

The  Society  then  adjourned. 

©orrjeBpottdjenjce. 

SOME  OBJECTIONS  TO  THE  USE  OF  PEPTON- 
IZED  MILK  IN  THE  FEEDING  OF  INFANTS. 

To  THs  Editob  op  Thb  Mjuxoo.  Rbookd. 

Sir  :  The  importance  of  the  subject  of  the  artificial  feed- 
ing of  infants,  and  the  difficulty  of  finding  an  efficient 
substitute  for  mother's  milk  may,  I  trust,  prove  sufficient 
excuse  for  mjr  transgression  on  your  valuable  space. 
Since  the  pubhcation  of  your  editorial  and  the  communi- 
cation of  Professor  J.  Lewis  Smith  in  regard  to  the  above 
subject,  I  have  adopted  the  plan  therein  recommended 
for  peptonizing  milk,  and  I  would  ask  correction  on  the 
following  points :  Casein,  being  an  albuminoid,  is  largely 
acted  upon  in  the  stomach  and  absorbed  directly  from 
that  viscus,  and  only  those  portions  which  may  escape 
into  the  intestine  are  acted  upon  by  the  pancreatic  secre- 
tion. It  seems  rational  that  the  immediate  coagulation 
of  the  casein  in  the  stomach  is  to  prevent  its  passage 
through  the  pylorus  until  acted  upon  by  the  pepsin  of  the 
gastric  secretions  in  presence  of  an  acid.  By  introduc- 
ing an  excess  of  ajkali  with  the  milk  the  gastric  secretion 
is  rendered  in6rt  (for  the  time  being)  and  the  milk  does 
not  coagulate,  but  passes  on  into  contact  with  the  secre- 
tions of  the  pancreas,  small  intestine,  etc.,  where  it  is  only 
farticUly^  converted  into  albuminose.  Stomach  digestion 
IS,  by  this  plan  of  management,  practically  "  eliminated." 
The  milk,  instead  of  being  retained  for  several  hours,  as  it 
is  in  the  stomach  (normally),  in  direct  contact  with  the 
gastric  ferment,  passes  ftoo  rapidly  ?)  on  through  the  in- 
testine. In  patients  with  "intestinal  catarrh,"  fed  on 
peptonized  milk,  some  of  the  dejections  consisted  of  two 
nearly  distinct  portions :  a  greater  or  less  amount  of  mu- 
cus and  a  perfectly  homogeneous  mass  of  putty-like,  par- 
tially digested  casein.  The  quantity  of  food  allowed  was 
one  fluid  ounce  every  four  hours ;  Fairchild's  pancreatin 
was  used,  with  Squibb' s  sodium  bicarbonate,  five  grains 
of  the  former  to  fiifteen  grains  of  the  latter,  the  details  of 
the  process  as  published  having  been  carefully  carried 
out.  In  cases  in  which  vomiting  is  not  troublesome, 
would  it  not  be  rational  to  confine  digestion  to  the  stom- 
ach, as  far  as  possible,  with  the  object  of  relieving  the 
inflamed  intestine  ?  I  am  induced  to  make  these  crude 
suggestions  in  the  hope  that  a  **  weighty  word  "  may  be 
elicited  in  reply.     Very  respectfully, 

N.  E.  Oliver,  M.D. 


364 


THE  MEDICAL  RECORD. 


[September  27, 1884. 


THE    USE    OF    PEPTONIZED    MILK    FOR 
INFANTS. 

To  THB  Editor  or  Thb  Mbdical  Rbcdsd. 

Sir  :  There  is  a  practical  objection  to  the  use  of  pepton- 
ized milk  for  infants  in  the'  manner  that  has  been  sug- 
gested by  Dr.  Smith  and  others.  It  consists  in  the  fact 
that  young  infants  have  to  be  fed  in  the  middle  of  the 
night.  Now  a  sleepy  mother,  however  affectionate,  will 
not  be  disposed  to  get  up  at  2  a.m.,  prepareithe  milk, 
warm  the  water,  and  wait  twenty  minutes  for  the  mixture 
to  digest,  while  the  infant  ad  interim  howls,  wakes  up 
the  male  parent,  and  disturbs  the  household  generally. 

I  would  inquire  whether  a  little  pepsin  containing  the 
curdling  ferment  or  a  little  gelatine  will  not  do  just  as 
well.  Also,  whether  the  casein  m  condensed  milk  does  not 
coagulate  in  fine  flakes.  Certainly  I  have  found  con- 
densed milk  to  nourish  children  admirably,  despite  its 
sweetness.     Yours,  vcr}'  truly,  M.  S. 

Philadblphia,  Sq[>tember  3,  1884. 


THE  J^ORTH  CAROLINA  CLIMATE  FOR  CON- 
SUMPTIVES. 

To  THB  Editor  op  Thb  Mbdical  Rbcord. 

Sir  :  Physicians  are  sending  consumptives  from  the 
Northern  and  New  England  States  to  California,  Colo- 
rado, Texas,  and  Florida,  when  there  is  a  more  accessible 
and  equally  eiiicacious  region  much  nearer.  I  refer  to 
Western  North  Carolina,  of  which  region  Asheville,  Bun- 
combe County,  is  the  metropolis,  railroad  centre,  and 
great  health  resort  for  winter  and  summer.  Fifteen  years 
ago  my  father,  Dr.  H.  P.  GatchelJ,  Sr.,  wrote  a  pam- 
phlet on  this  region,  from  which  I  get  my  facts  regarding 
the  climate.  Asheville  is  2,250  feet  above  tide-water; 
it  is  a  place  of  five  or  six  thousand  inhabitants.  It  has 
six  hotels  and  boarding-houses,  capable  of  caring  for 
twenty-five  hundred  guests.  There  is  a  club-house,  a 
public  library  with  free  reading-room,  and  there  are  the 
usual  churches  and  schools  found  in  a  place  of  this  size. 
The  climate  of  Asheville  compares  favorably  with  that 
of  Geneva  in  Switzerland,  Turin  and  Milan  in  Italy,  and 
Vienne  in  the  valley  of  the  Rhone,  East  France. 

spring.  Summer.       Autumn.  Winter.  Year. 

Temp.  deg.    Temp.  deg.    Temp.  deg.    Temp.  deg.    Temp.  deg. 

Geneva. .     52.2  70.3         54.2  34.0  52.7 

Turin....     53.7  71.5         53.8  33.5  53.1 

Asheville.     54.3  71.3         55.3  37.8  55.3 

Vienne..     56.2  71.8         54.6  38.7  55-3 

Milan  . . .     54.9  72.8        55.9  36.1  54.9 

From  the  above  table  it  may  be  seen  that  the  winter 
climate  of  Asheville  is  milder  than  any  of  the  places 
with  which  it  is  compared  except  Vienne.  This  place  is 
enjoying  a  wide  reputation  as  a  resort  for  the  cure  of  in- 
cipient phthisis.  The  writer  has  known  of  not  a  few 
complete  recoveries,  and  many  desperate  cases  which 
greatly  improved.  To  show  the  immunity  of  this  region 
from  pulmonary  disease,  I  append  the  following  table. 
Out  of  every  1,000  deaths  .there  are  from  consumption 

In  Northern  New  England  (nearly) 250 

In  Minnesota  and  California 150 

In  Kentucky  and  Tennessee  (nearly). ,.      100 

In  Louisiana  and  Florida 50 

In  Western  North  Carolina 30 

Dr.  Cain,  formerly  of  Charleston,  S.  C,  says  that  not 
one  of  the  many  consumptives,  in  different  stages  of  the 
disease,  that  he  has  sent  to  Asheville,  has  failed  to  im- 
prove ;  and  he  regards  it  as  the  most  healthful  country 
in  the  world. 

The  distinguished  Professor  Dickson,  of  Jeflferson 
Medical  College,  stated  that  he  and  his  family  nowhere 
improved  so  much  as  in  Asheville.  He  is  "  not  aware 
of  any  spot,  in  Europe  or  America,  so  full  of  all  that  is 
desirable." 

Dr.  S.  E.  Chaill6,  of  New  Orleans,  who  spent  from 
three  to  five  months  in  this  region  annually  for  four 
years,  wrote  that  he  had  seen  but  one  case  of  consump- 
tion,  a  mulattress,  and  not  a  native  of  this  section      The 


above  is  taken  from  an  article  by  Dr.  Chaill^  which 
may  be  found  in  the  Medical  and  Surgical  Reporter  for 
April,  1878,  p.  269;  and  in  which  he  gives  the  results 
obtained  at  this  place  by  Dr.  W.  Gleitzman  in  his  Sanu 
tarium  ;  he  stated  that  every  incipient  case  of  consump. 
tion  was  cured,  or  the  disease  arrested  and  the  patient 
so  much  improved  that  it  was  safe  to  say  that  the  im- 
provement  would  go  on  to  complete  cure  under  the 
same  conditions. 

The  scenery  is  grand  and  picturesque.  On  the  West- 
em  North  Carolina  Railroad  there  are  feats  of  engineer- 
ing, and  bits  of  scenery  surpassing  anything  in  the 
mountains  of  Pennsylvania,  and  equalled,  perhaps,  no- 
where in  the  country. 

The  people  are  kind  and  hospitable,  and  life  and  prop. 
erty  are  as  safe  as  in  any  section  of  the  United  States. 
Edwin  A.  Gatchell,  M.D. 

Asheville,  N.  C. 


Official  List  ^  Changes  in  the  Stations  and  Dutus  ef  Oj/Uefs 

serving  in  the  Afeaical  DefiartwutU^  United  Statu  Army^ 
from  September  14  to  September  20,  1884* 

Caldwell,  D.  G.,  Major  and  Surgeon.  Granted  leave 
of  absence  for  one  month  and  twenty  days,  to  commence 
about  October  15,  1884.  S.  O.  95,  Headquarters,  Di- 
vision of  the  Missouri,  August  16,  1884. 

Cronkhite,  Henry  M.,  Captain  and  Assistant  Sur- 
geon.  From  Department  of  the  Platte  to  Department 
of  the  Missouri.  S.  O.  215,  par.  i,  A.  G.  O.,  September 
13,  1884. 

Taylor,  Arthur  W.,  First  Lieutenant  and  Assistant 
Surgeon.  From  Department  of  the  Missouri  to  Depart- 
ment of  the  Platte.  S.  O.  215,  par.  i,  A.  G.  O.,  Septem- 
ber 13,  1884. 

Wilson,  William  J.,  Captain  and  Assistant  Surgeon. 
From  Department  of  Dakota  to  Department  of  the  East. 
S.  O.  220,  par.  I,  A.  G.  O.,  September  19,  1884. 

Gardiner,  J.  ds  B.  W.,  Captain  and  Assistant  Sur- 
geon. From  Department  of  Arizona  to  Department  of 
the  East.  S.  O.  220,  par.  i,  A.  G.  O.,  September  19, 
1884. 

CoRBUSiER,  William  H.,  Captain  and  Assistant  Sur- 
geon. From  Department  of  the  East  to  Department  of 
Arizona.   S.  0. 220,  par.  i,  A.  G.  O.,  September  19, 1884. 

La  Garde,  L.  A.,  Captain  and  Assistant  Surgeon. 
From  Department  of  Missouri  to  Department  of  Dakota. 
S.  O.  220,  par.  1,  A.  G.  O.,  September  19,  1884. 

Barrows,  C.  C.,  First  Lieutenant  and  Assistant  Sur- 
geon. Granted  one  month's  leave  of  absence,  with  per- 
mission to  apply  to  the  proper  authority  for  an  extension 
of  one  month.  S.  O.  86,  par.  4,  Headquarters  Depart- 
ment of  Arizona,  September  13,  1884. 


lltXcdical  Items. 


Contagious  Diseases — Weekly  Statement.— Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  September.  20,  1884 : 


Week  Ending 


Casts. 

September  13,  1884 
September  20, 1884 

Dtaiks, 
September  13,  1884 
September  20,  1884 


6 

4 


II     o 

19    o 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  a6,  No.  14 


New  York,  October  4,  1884 


Whole  No«  736 


®ri0itml  %x\Xt\t^. 


THE  THREE  TONSILS —  SOME  PRACTICAL 
SUGGESTIONS  IN  REGARD  TO  THEIR 
STRUCTURE,  FUNCTION,  AND  DISEASES/ 

By  F.  H.  BOSWORTH,  M.D., 
raonssoK  of  disbasbs  op  thb  throat  in  bbllbvub  hospital  mxdical  col- 

LKGB.  NEW  YORK. 

I  INVITE  your  attention  this  evening  to  a  consideration 
of  the  three  tonsils,  in  order  that  I  may  bring  forward 
certain  views  in  regard  to  them  which  I  have  for  some 
time  entertained,  and  which,  while  contrary,  I  think,  to 
the  generally  accepted  opinion,  will,  if  true,  serve  to  clear 
up  much  that  is  vague  in  the  prevailing  views  as  to  the 
functions  of  these  glands,  and  also  to  give  a  more  prac- 
tical direction  to  our  therapeutical  measures  in  the  man- 
agement of  many  of  the  commoner  forms  of  disease  in 
the  fauces. 

By  the  three  tonsils  it  is  to  be  understood  that  I  refer 
to  the  two  glandular  masses  found  between  the  pillars  of 
the  fauces,  and  to  which  the  name  tonsil  is  usually  ap- 
plied, and  to  that  mass  of  glands  which  is  found  in  the 
vault  of  the  phaiynx,  and  which  was  first  recognized  and 
described  by  William  Hunter,"  and  subsequently,  and  to  a 
fuller  extent,  by  Luschka,'  and  to  which  the  name  of 
Luschka's  tonsil  has  been  given,  and  also  that  of  the 
pharyngeal  tonsil.  These  three  masses  being  so  nearly 
identical  in  their  structure,  function,  and  diseases,  I  think 
that  they  may  be  properly  designated  as  the  three  tonsils. 
The  masses  between  the  pillars  of  the  fauces  will  be 
spoken  of  as  the  faucial  tonsils,  while  that  structure  at 
the  vault  of  the  pharynx  will  be  designated  as  the  pharyn- 
geal tonsil. 

It  has  been  the  custom  to  describe  the  faucial  tonsils 
as  **  two  almond-shaped  organs  lying  between  the  pillars 
of  the  fauces,  and  covered  by  a  fibrous  investing  mem- 
brane or  sheath,  in  which  are  from  seven  to  twelve  open- 
ings, which  mark  the  orifices  of  a  number  of  mucous 
glands,  of  which  the  organs  are  composed."  There  are, 
I  think,  several  sources  of  error  in  this  description.  The 
fatida]  tonsil  is  not  covered  by  a  fibrous  sheath.  Under- 
lying it  there  is  a  more  or  less  dense  connective-tissue 
layer,  which  is  continuous  with  the  submucous  layer  which 
underlies  all  mucous  membranes.  Beneath  the  mass 
this  is  thickened  by  the  same  morbid  process  which  has 
developed  the  tonsil.  Further  than  this  there  is  no  sheath 
to  the  gland.  It  is  not  an  almond-shaped  organ  as  a 
rule,  but  is  of  whatever  shape  the  morbid  process  which 
has  caused  its  growth  may  give  it.  The  number  of 
openings  on  its  surface  is  entirely  dependent  upon  the 
number  of  the  glands  which  are  involved  in  the  hyper- 
trophic processes  which  have  produced  it.  It  is  not  an 
organ  of  the  body  in  the  sense  that  the  liver  and  spleen 
are  organs,  and  which  I  think  is  a  commonly  accepted 
view,  and  therefore,  in  this  sense,  has  no  especial  func- 
tion to  jperform  in  the  economy.  In  my  work  on  "  Dis- 
eases of  the  Throat,"  published  three  years  ago,  I  sub- 
jected myself  to  criticism  by  the  assertion  that  in  the 
healthy  throat  there  are  virtually  no  tonsils.  This  opin- 
ion I  still  entertain.  The  "  almond-shaped  organ,"  etc, 
described  by  anatomists  does  not  exist  in  a  healthy  throat, 

*  Read  before  the  New  York  Academy  of  Medidue,  October  a,  1884. 

*  Cohen  :  Diseases  of  the  Throat,  second  editioo,  p.  253. 

*  Der  Schlundkopf  der  Menschen. 


but  is  the  result  of  a  morbid  process.  This  morbid  pro- 
cess may  have  been  of  such  limited  extent  as  to  have  de- 
veloped but  a  small  tonsil,  and  one  not  sufficient  to  give  rise 
to  any  other  than  trivial  symptoms  ;  or  it  may  have  goti^e 
CO  the  extent  of  developing  a  mass  of  svillicient  extent  to 
cause  serious  disturbances.  All  mucous  membranes  are 
richly  endowed  with  glands,  in  order  thut  they  may  be 
kept  in  that  soft  and  pliable  condition  which  the  proper 
performance  of  their  functions  demands.  Perhaps  no 
portion  of  the  mucous  tract  demands  a  greater  supply  of 
mucus  in  the  performance  of  its  functions  than  the  up- 
per air-tract.  In  this  region,  therefore^  we  find  these 
muciparous  glands  not  only  richly  distributed  throughout 
the  membrane,  but  also  aggregated  in  masses.  This  ten- 
dency to  aggregation  is  especially  noticeable  in  the  pharyn- 
geal vault,  and  between  the  pillars  of  the  faucei^.  In  a 
condition  of  health  these  aggregations  of  glands  do  not 
project  prominently  from  the  membrane,  and  hence,  in  a 
perfectly  healthy  state,  their  existence  is  not  easily  demon- 
strated by  gross  inspection. 

The  mucous  membrane  of  the  upper  air  passages, 
however,  perhaps  more  than  any  other  portion  of  the  ' 
body,  is  liable  to  be  the  seat  of  morbid  action.  It  is  a 
very  noticeable  clinical  fact,  also,  that  while  in  adults  it  is 
the  mucous  membrane  proper  which  is  most  liable  to  be 
the  seat  of  disease,  in  children  it  is  the  glandular  structures 
which  are  especially  susceptible  ;  hence  we  -  find  that 
morbid  conditions  of  these  glands,  both  in  the  fauces 
and  in  the  pharyngeal  vault,  are  of  exceedingly  frequent 
occurrence,  especially  in  children. 

The  tendency  of  chronic  inflammatory  processes  is  to 
develop  in  hypertrophy.  Hence  wc  find  a  moderate 
hypertrophy  of  these  glandular  masses  of  exceedingly 
frequent  occurrence  in  young  people,  constituting  in  thft 
one  case  so-called  enlarged  faucial  tonsils,  and  in  the 
other  an  enlarged  pharyngeal  tonsil. 

In  order  to.  msike  clearer  my  meaning*  I  will  very 
briefly  allude  to  the  anatomy  and  functions  of  the  upper 
air-tra^t.  The  nasal  cavity  proper  extends  from  the 
nostrils  in  front  to  the  posterior  nares  behind.  They  are 
lined  by  mucous  membrane  covered  with  columnai-  cili- 
ated  epithelia,  whose  ciliae  move  in  a  direction  from  be- 
hind forward.  These  cavities  fulfil  a  double  function  \ 
they  contain  the  distribution  of  the  olfactory  nerve  and 
preside  over  the  function  of  olfaction.  With  this  wc 
have  nothing  to  do  in  the  present  consideration.  The 
other  function  consists  in  guarding  the  entrance  to  the 
lungs,  warming,  moistening,  and  cleansing  the  inspired  air* 
For  the  latter  purpose  the  nasal  mucoijs  membrane  is 
very  richly  supplied  with  glands  which  pour  out  an  abun- 
dant sero-mucus,  by  which  the  inspired  air  becomes 
charged  with  moisture.  The  nasal  cavities,  then,  belong 
purely  to  the  air-tract.  Behind  the  nasal  chamber  lies 
the  pharynx.  This  is  usually  described  as  one  cavity, 
extending  from  the  basilar  process  of  the  occipital  bone 
to  the  oesophagus.  There  is,  I  think,  a  source  of  error  in 
this.  That  portion  of  the  pharynx  which  lit^s  above  the 
border  of  the  soft  palate  is  lined  with  a  mucous  mem- 
brane covered  with  columnar  ciliated  epitlielia,  and  very 
richly  endowed  with  muciparous  glands, '  those  in  the 
vault  constituting  the  pharyngeal  tonsiL  Below  the  border 
of  the  soft  palate  the  pharynx  is  lined  with  a  mucous 
membrane,  which  is  covered  with  pavement  epilhelia  and 
very  scantily  supplied  with  glands.  The  characteristic 
anatomical  feature  of  the  air-passages  is  that  they  are 
lined  with  a  mucous  membrane  covered  by  columnar 


I 


366 


THE   MEDICAL  RECORD. 


[October  4,  1884. 


ciliated  epithelia,  and  richly  endowed  with  mucous 
glands ;  a  form  of  mucous  membrane  which,  while  ex- 
ceedingly delicate  and  sensitive,  is  eminently  adapted  to 
its  function.  It  tolerates  the  passage  of  air,  corrects  its 
temperature,  regulates  its  humidity,  and  prepares  it  for 
the  lungs.  At  the  same  time  it  resents  the  impact  of 
any  foreign  body,  harsh  substance,  or  the^entrance  of  any 
irritating  gas  or  vapor.  It  is  also  endowed  with  glands 
which  secrete  a  more  fluid  mucus,  more  of  the  character 
of  a  sero-mucus. 

On  the  other  hand,  the  food-passage  is  lined  with  a 
inucdus  membrane  which  is  covered  with  squamous  epi- 
thelia. Its  function  is  to  allow  the  passage  of  masses  of 
food  of  oftentimes  firm  consistence,  but  whose  impact 
upon  the  membrane  of  the  air-passage  would  not  be  toler- 
aited.  For  this  purpose  the  niembrane  is  so  constructed 
that  it  is  hard,  dense,  and  resisting,  and  not  especially 
sensitive.  It  is  richly  endowed  with  glands  which  pour 
out  a  viscid  mucus,  whose  function  is  as  a  lubricant 
mainly. 

The  pharynx,  then,  as  it  is  usually  described  by 
anatomists,  is  really  composed  of  two  cavities  differing 
materially  in  structure  and  function.  The  upper  pharynx 
belongs  to  the  air-tract,  while  the  I6wer  pharynx  belongs 
to  the  food-tract.  This  view  is  still  further  sustained  by 
the  fact  that  an  inflammatory  process  in  the  one  region 
does  not  involve  the  other  as  a  rule.  A  pharyngitis  in- 
volving the  lower  pharynx  is,  I  thiqk,  a  very  rare  disease, 
and  when  met  with,  is  not  connected  with  any  morbid 
condition  of  the  upper  pharynx,  but  rather  with  some  dis- 
turbance of  the  food-tract,  such  as  a  gastritis,  etc. 

The  lower  pharynx,  as  before  remarked,  is  very  scantily 
supplied  with  glands,  and  yet  in  the  peiformance  of  its 
functions  it  demands  an  abundant  supply  of  mucus,  in 
order  that  it  may  be  kept  sufficiently  lubricated  to  allow 
of  the  easy  passage  of  food  in  deglutition.  Gland  struc- 
tures are  exceedmgly  delicate,  and  liable  to  injury  on 
exposure.  The  lower  pharynx  is  perhaps  the  most  ex- 
posed region  of  the  mucus  tract ;  it  is  tfierefore  a  hard, 
dense  membrane  with  but  few  glands.  In  order  to  com- 
pensate for  this  deficiency  it  is  surrounded  on  three 
sides  with  large  aggregations  of  glands,  one  on  either 
side  between  the  pillars  of  the  fauces,  another  inime- 
diately  above  in  the  vault  of  the  pharynx,  constituting 
in  the  one  case  the  faucial  tonsils,  in  the  other  the 
pharyngeal  tonsil  The  sole  and  only  function  of  these 
masses  of  glands  which  constitute  the  three  tonsils  is,  I 
believe,  to  supply  mucus  to  moisten  and  lubricate  the 
lower  pharynx,  and  the  design  of  Nature  in  so  locating 
them  has  been  most  wise,  for  had  the  lower  phar3nix  been 
endowed  with  glands  sufficient  for  its  demands,  disease 
occurring  in  them  would  be  attended  with  far  graver  con- 
sequences than  attend  morbid  conditions  of  the  gland 
arranged  as  we  find  them. 

The  minute  anatomical  structure  of  the  faucial  and 
pharyngeal  tonsils  have  been  so  often  described  that 
further  allusion  to  them  need  not  be  made.  Their  resem- 
blance is  so  clear  that  the  only  difference  in  structure  is 
easily  accounted  for  by  the  fact  that  the  pharyngeal  tonsil 
is  protected  from  any  impact  of  foreign  substances,  and 
i^  therefore  of  a  soft  and  spongy  consistence,  and  con- 
tains connective  tissue,  less  in  amount  and  less  firmly 
organized  than  the  faucial  tonsils,  which  are  subjected  to 
much  harsher  usage  in  the  act  of  deglutition. 

From  a  patholpgical  point  of  view  we  find  stijl  further 
grounds  for  grouping  the  three  tonsils  together,  for  the 
same  morbid  processes  which  occur  in  the  faucial  tonsils 
are  met  with  in  the  pharyngeal  tonsil.  These  are:  acute 
inflammation ;  chronic  inflammation,  resulting  in  hyper- 
trophy ;  acute  follicular  inflammation ;  croupous  inflam- 
mation, and  diphtheritic  inflammation. 

Acute  tonsillitis  is  a  name  generally  given  to  quinsy. 
I  shall  endeavor  to  show  later  that  quinsy  is  not  a  dis- 
ease of  the  tonsil,  but  is  an  inflammation  of  the  cellular 
tissue  of  the  soft  palate  or  neighboring  parts,  and  that 
phlegmonous  inflammation  does  not  occur  in  the  tonsil. 


As  a  matter  of  fact,  therefore,  the  only  form  of  acute  in- 
flammation met  with  in  the  tonsil  is  a  catanhal  inflam- 
mation, viz.,  one  attended  with  hyperaemia,  swelling,  and 
hypersecretion.  This  is  usually  described  under  the 
term  subacute  inflammation.  In  deference  to  common 
usage,  therefore,  I  use  the  usual  nomenclature. 

Subacute  tonsillitis, — This  in  the  faucial  tonsil  consists 
of  a  mild  form  of  inflammatory  action  characterized  by 
swelling  and  hyperaemia  of  the  glands,  and  is  the  result, 
generally,  of  exposure  to  cold.  The  constitutional  dis- 
turbance is  not  great,  there  being,  as  a  rule,  a  mere  feel* 
ing  of  general  malaise  with  chilly  sensations.  The  ton- 
sils are  swollen  to  twice  or  three  times  their  size  in  the 
quiescent  state,  and  project  into  and  encroach  upon  the 
isthmus  of  the  fauces,  two  red,  angry^looking  masses. 
The  palate  may  be  involved  in  the  hyperaemia,  but 
there  is  no  notable  swelling  beyond  the  tonsil  proper. 
The  attack  is  not  of  any  serious  import,  and  runs  its 
course  in  from  four  to  seven  days.  The  predisposmg 
cause  is  enlarged  tonsils,  and  it  occurs  in  children  more 
frequently  than  in  adults,  simply  for  the  reason  that  in 
children  enlarged  tonsils  are  most  frequently  met  with. 
Subacute  tonsillitis  occurs  in  the  pharyngeal  tonsil  with 
the  same  frequency  as  in  the  fauci^  tonsil ;  it  is  attended 
by  the  same  constitutional  symptoms,  a  mild  febrile  dis- 
turbance, and  no  more ;  and  it  is  caused,  as  a  rule,  by  ex- 
posure to  cold.  The  main  predisposing  cause  is  an  en- 
larged pharyngeal  tonsil.  It  occurs  most  frequently  in 
children,  runs  its  course  and  subsides  in  the  same  way  as 
the  faucial  disease.  The  only  difference  in  the  two  affec- 
tions is  in  the  symptoms,  which  differ  merely  from  the 
location  of  the  morbid  process.  As  far  as  I  know,  the 
afifection  has  never  been  described  under  the  above 
heading,  although  Me^er,  in  his  original  article  on 
"Adenoid  Vegetation  m  the  Naso-pharyngeal  Cavity,"* 
described  their  tendency  to  sudden  attacks  of  turgescence, 
by  which  their  size  varied  greatly  at  different  examina- 
tions. 

Lowenberg "  and  other  writers  allude  also  to  the  same 
symptom.  It  will  be  easily  understood  how,  in  tlie  case 
of  a  mild  inflammatory  process  occurring  in  the  pharyn- 
geal tonsil,  the  symptoms  will  be  mainly  nasal.  There  is 
apparently  a  cold  in  the  head.  The  nasal  passages  are 
obstructed,  the  voice  becomes  affected,  changing  to 
what  Meyer  calls  the  dead  voice,  its  nasal  resonance  is 
destroyed,  and  there  is  more  or  less  discharge  of  mucus 
or  muco-pus  into  the  fauces.  The  attack  is  what  is 
usually  regarded  as  a  cold  in  the  head,  and  is  often  called 
an  acute  coryza.  This,  I  think,  is  a  frequent  error.  An 
acute  inflammation  of  the  nasal  mucous  membrane  in 
children  is  very  rare.  As  before  remarked,  the  glandu- 
lar structures  are  the  parts  generally  attacked  in  children 
and  not  the  mucous  membrane  proper,  and  their  colds, 
if  in  the  throat,  are  in  the  faucial  tonsils,  and  if  in  the 
nasal  passages,  are  in  the  pharyngeal  tonsil  rather  than 
in  the  nasal  membrane.  The  attack  subsides  in  a  few 
days,  as  in  the  faucial  disorder,  its  frequent  recurrence, 
however,  should  call  attention  to  the  probable  existence 
of  the  chronic  disorder  which  is  in  most  cases  the  predis- 
posing cause  of  the  attack. 

Acute  follicular  tonsillitis. — The  epidemic  of  this 
disease,  which  prevailed  to  such  a  great  extent  last 
spring,  and  indeed  which  has  prevailed  so  extensively 
in  the  past  three  or  four  years,  has  served  to  bring  it 
prominently  to  the  attention  of  all  of  us.  It  consists  of 
an  inflammatory  process,  involving  one  or  both  tonsils, 
which  is  characterized  by  the  exudation  into  the  crypts 
of  the  glands  of  a  fibrinous  material  which  fills  and  dis- 
tends their  cavities.  The  onset  of  the  attack  is  marked 
by  a  chill,  .followed  by  general  febrile  disturbance  of  a 
marked  character.  The  skin  becomes  hot  and  flushed, 
there  are  headache,  pains  in  the  bones,  loss  of  appetite, 
and  all  the  evidences  of  a  febrile  movement  far  greater 


'  Medioo-Chinu:pcaI  Transactions,  vol.  lifi.    London,  187a 
f^'  Les  Tumeurs  Ad^noldes  du  phaiynx  xaaaX. 


October  4.  1884.] 


THE  MEDICAL  RECORD. 


367 


than  can  be  accounted  for  by  the  amount  of  local  inflam- 
matory action.  !.    ,  ■  . 

In  a  paper,  read  at  the  meetmg  of  the  Arnencan 
I^aryngological  Association  in  May  last,  on  "  The  Clinical 
Stfoificance  of  Fibrinous  Exudations,**  *  I  took  the 
groond  that  this  disease  is  an  essential  fever  with  a  local 
manifestation  in  the  throat,  something  in  the  nature  of 
one  of  the  exanthemata,  I  think  there  is  much  ground 
for  regarding  this  as  the  correct  view.  In  the  same  paper 
I  called  attention  to  the  fact  that  the  same  disease  oc- 
curred frequently  in  the  pharyngeal  tonsil.  In  each  case 
the  onset  and  progress  of  the  disease  is  characterized  by 
the  same  symptoms,  the  only  difference  being  in  the 
locality  of  the  eruption,  and  in  the  subjective  symptoms 
with  reference  to  pain  in  deglutition,  etc. 

Croupous  tonsillitis. — During  the  prevalence  of  follic- 
ular tonsillitis  we  meet  frequently  with  cases  in  which 
the  attack  is  marked  by  the  same  group  of  local  and 
constitutional  s)anptoms,  with  the  exception  that  an  in- 
spection of  the  fauces  reveals,  in  place  of  the  small 
pearly  white  spots  on  the  tonsil,  a  broad  membrane 
covering  more  or  less  the  whole  face  of  the  gland. 
This  I  regard  as  the  same  disease  as  the  former,  with  an 
eruption  which  is  more  marked  or  efflorescent.  The 
exudation  which  in  the  former  case  confines  itself  to  the 
crypts  of  the  glands,  in  the  latter  fills  and  overflows  them, 
forming  a  continuous  membrane.  If  this  be  detached 
from  the  surface,  there  will  be  found  beneath  it  the 
appearances  of  the  follicular  disease. 

The  same  membrane  I  have  frequently  observed  on 
the  pharyngeal  tonsil,  and  its  appearance  is  attended 
with  the  same  general  symptoms  as  in  the  faucial  disease. 
Diphtheritic  totisillitis, — A  diphtheritic  membrane  on 
the  faucial  or  phar3mgeal  tonsil  occurs  in  connection 
with  the  blood-poison  of  diphtheria.  Wherever  it  may 
be  developed,  its  clinical  significance  is  the  same. 

Hypertrophied  tonsils. — Hypertrophy  of  the  faucial 
tonsUs  gives  rise  to  a  train  of  symptoms  which  are  mainly 
due  to  the  mechanical  presence  of  these  glandular 
masses  in  the  fauces.  They  occur  mostly  in  young 
people.  Their  development  is  attended  by  the  occur- 
lence  of  repeated  attacks  of  subacute  inflammation  or 
ordinaiy  catarrhal  sore  throat,  and  they  show  a  tendency 
to  subside  at  puberty.  Their  development  also  is  the 
f^t  of  a  purely  local  morbid  process,  and  is  not,  as  a 
rale,  the  outcropping  of  any  of  the  constitutional  dys- 
mast.  If  there  is  any  impairment  of  health,  it  is  to  be 
accounted  for  by  the  mechanical  action  of  the  growths, 
ID  obstructing  respiration,  disturbing  sleep,  or  otherwise 
interfering  with  the  natural  functions. 

Hypertrophy  of  the  pharyngeal  tonsil  has  been  de- 
scribed by  many  writers  under  the  heading  usually  of 
adenoid  tumors,  or  vegetations  at  the  vault  of  the 
pharynx.  It  seems  to  me  that  a  clearer  coniprehen- 
Ron  of  this  affection  would  be  reached  by  showing  its  re- 
lation with  enlarged  faucial  tonsils.  This  form  of  hyper- 
trophy, like  that  in  the  faucial  tonsil,  occurs  mostly  in 
young  people  ;  it  gives  rise  to  a  train  of  symptoms  which 
»e  largely  mechanical ;  its  deV^elopment  is  attended  by 
lepeated  attacks  of  subacute  inflammation  ;  it  is  a  purely 
kcal  trouble ;  it  shows  a  tendency  to  subside  with  the 
Attainment  of  puberty,  and  in  fact  in  all  its  aspects  is 
identical  with  the  faucial  disorder,  except  in  its  location. 
In  this  view,  then,  enlarged  tonsils  in  either  region  are 
simply  masses  of  diseased  glands,  whose  function  has  in 
Ibe  main  been  abolished  or  perverted  by  the  morbid  pro- 
cess which  has  fixed  itself  upon  them.  If  the  hypertro- 
Pjiic  process  is  limited  and  the  tonsils  are  of  small  size, 
giring  rise  to  no  untoward  symptoms,  either  by  their 
mechanical  interference  with  function,  or  by  exciting  an 
formal  discharge  from  the  parts,  they  require  no  treat- 
laent.  I^  on  the  other  hand,  the  hypertrophy  has  gone 
{0  the  extent  of  developing  a  glandular  mass,  which  by 
tts  presence  interferes  with  the  function  of  the  parts,  'or 


1  :New  Yerk  Medical  Jouraal,  May  12,  1884. 


which  in  any  way  gives  rise  to  serious  symptoms,  it  seems 
to  me  that  there  should  be  no  question  as  to  the  proper 
remedy.  They  are  diseased  structures  and  should  be  ex- 
tirpated. This  rule,  I  think,  should  apply  whether  we 
have  to  deal  with  an  exceptionally  large  mass,  or  with  a 
single  follicle  not  larger  than  a  split  pea.  As  regards 
any  local  medication  I  believe  it  to  be  absolutely  inert 
in  redticing  genuinely  hypertrophied  glands.  It  is  some- 
times said  that  Nature  placed  these  tonsils  in  the  throat, 
and  that  they  should  not  be  removed.  Nature  certaiiily 
never  put  them  there. 

Perhaps  one  of  the  most  remarkable  suggestions  ever 
made  in  regard  to  the  tonsils  was  that  of  Penrose,  that 
their  removal  might  result  in  a  loss  of  virile  power.  This 
strange  suggestion  has  been  so  completely  answered  by 
Daly,*  that  I  only  allude  to  it  as  a  curiosity.  It  is  some- 
times suggested  that  a  portion  of  the  tonsil  might  be  re- 
moved, but  not  all.  I  see  no  more  reason  for  this  than 
for  the  removal  of  only  a  portion  of  any  other  morbid 
growth,  a  fibroid  for  instance.  The  danger  of  hemor- 
rhage after  tonsillotomy  has  often  been  urged  as  an  ob- 
jection to  the  procedure.  This  danger  is,  I  believe, 
overestimated.  Literature  records  no  fatal  case,  as  far 
as  I  know,  with  the  exception  of  those  cases  in  which  the 
carotid  artery  was  cut.  I  cannot  conceive  of  an  intelli- 
gent operator  making  this  blunder.  Furthermore,  it 
should  be  stated,  hemorrhage  never  occurs  in  the  opera- 
tion upon  children.  The  nutrient  artery  of  the  tonsil  in 
young  people  is  small  and  its  walls  collapse  easily.  In 
adults,  on  the  other  hand,  hemorrhage  afler  tonsillotomy 
is  almost  the  rule.  This  is  often  exceedingly  trouble- 
some. I  have  never  seen  a  case,  however,  in  which  the 
bleeding  was  not  promptly  arrested  by  the  application  of 
a  wire  heated  to  a  dull,  red  heat  This  is  a  simple  pro- 
cedure and  should  be  resorted  to  always  in  preference  to 
the  ordinary  styptics,  which  are  useless  in  controlling  arte- 
rial hemorrhage,  and  the  only  troublesome  bleeding 
which  occm's  in  these  cases  is  from  the  nutrient  artery. 

As  regards  the  removal  of  the  pharyngeal  tonsil  I  have 
nothing  to  say  in  addition  to  what  I  have  already  given 
before  the  Academy  *  two  years  ago. . 

Quinsy. — I  have  already  alluded  to  €[uinsy  as  a  disease 
of  the  cellular  tissue  of  the  fauces  rather  than  of  the  ton- 
sil. Phlegmonous  or  suppurative  disease  does  not  occur 
in  glandular  structures,  but  belongs  rather  to  areolar  ris- 
sue.  It  is  true  that  we  occasionally  meet  with  small  ab- 
scesses in  the  glands  of  the  tonsils  or  in  other  portions 
of  the  mucous  membranes  of  the  air-passages,  but  they 
are  small  abscesses,  as  a  rule,  which  result  from  the  oc- 
clusion of  a  gland,  and  are  not  phlegmonous  in  character. 
For  three  years  I  have  entertained  the  view  that  quinsy 
was  not  a  disease  of  the  tonsil,  and  in  that  time  have 
carefully  watched  and  examined  the  cases  which  have, 
come  under  my  observation,  and  I  do  not  recall  a  single 
instance  in  which  I  have  not  been  able  to  demonstrate 
conclusively  to  my  students,  or  others  who  have  been 
present  at  my  clinic,  that  the  tonsil  was  not  involved  di- 
rectly in  the  inflammatory  process.  The  tonsil  oftentimes 
presents  a  red  and  angry  appearance,  but  this  is  always 
secondary,  and  due  to  the  fact  of  its  nearness  to  the 
phlegmon.  Again,  the  tonsil  is  occasionally  very  promi- 
nent, being  lifted  from  its  bed,  and  at  times  projecting 
far  toward  the  opposite  side  of  the  fauces.  This  is  due 
to  the  phlegmon  occurring  behind  it.  The  disease  I  be- 
lieve to  be  an  acute  cellulitis  of  the  areolar  tissue  of  the 
fauces.  In  the  very  large  majority  of  cases  it  occurs  in 
the  soft  palate ;  in  others  it  occurs  in  one  or  the  other 
of  the  pillars  of  the  fauces ;  and  in  still  rarer  instances, 
in  the  pharyngeal  wall.  Furthermore,  the  cause  of  quinsy 
I  believe  to  be  in  very  many  cases  the  rheumatic  habit. 
This  view  is  an  old  one,  and  has  been  maintained  by 
many  writers  on  the  subject.  I  had  not  paid  any  close 
attention  to  this  view  until  Dr.  Fowler '  called  renewed 

>  Medical  and  Sureical  Reporter,  December  15,  1883. 

'  Growths  in  the  Nasal  Passages,  Medical  Record,  January  13, 1883. 

'  London  Lancet,  December  xi,  z88o. 


368 


THE   MEDICAL  RECORD. 


[October  4, 1884, 


attention  to  the  connection  between  rheumatism  and 
quinsy^  and  reported  a  number  of  cases  which  supported 
the  view.  Dr.  Fowler  also  suggested  the  value  of  the 
salicylates  in  the  treatment  of  the  disease. 

For  three  years  I  have  treated  all  my  cases  of  quinsy 
as  cases  of  phlegmonous  inflammation  of  the  submucous 
cellular  tissues,  and  as  probably  due  to  the  rheumatic 
habit.  The  following  summary  is  offered  as  affording 
some  points  of  interest :  The  whole  number  of  cases  seen 
has  been  133.  Males,  88  ;  females,  45.  Under  ten  years, 
3 ;  ten  to  twenty  years,  30  ;  twenty  to  thirty  years,  61  ; 
thirty  to  forty  years,  11 ;  over  forty  years,  12.  The  old- 
est case  was  sixty-nine  years,  the  youngest  nine  months. 
This  latter  case  was  a  female  diild  which  I  saw  the 
fourth  day  of  the  attack.  The  case  had  gone  to  suppura^ 
tion  and  I  opened  the  abscess  in  the  soft  palate. 

In  the  133  cases  the  phlegmon  was  in  the  soft  palate 
in  115  cases;  in  one  or  the  other  of  the  posterior 
pillars  of  the  fauces  in  1 1  cases  ;  beneath  the  tonsil  in  2 
cases,  and  in  the  wall  of  the  pharynx  in  2  cases.  These 
latter  two  cases  would  have  been  called  perhaps  retro- 
pharyngeal abscesses.  They  were  unquestionably  quinsy. 
In  many  cases  there  was  the  clinical  history  of  attacks  of 
rheumatism,  either  arthritic  or  muscular.  Unfortunately 
my  notes  give  no  accurate  information  as  to  the  propor- 
tion of  these  cases,  but  I  think  it  was  fully  sixty  per  cent 

If  the  effect  of  remedies  is  to  be  regarded  as  any  evi- 
dence, the  connection  between  the  two  diseases  is  still 
further  evidenced  by  the  fact  that  so  large  a  number  of 
cases  of  quinsy  were  aborted  by  the  early  administration  of 
the  salicylates.  These  cases  were  mostly  seen  at  my 
clinic  at  the  out-door  department  of  Bellevue  Hospital 
Many  of  them  came  several  days  after  the  onset  of  the 
attack.  Of  those  whom  I  saw  within  the  first  thirty-six 
hours,  the  attack  was  aborted  by  the  administration  of  the 
salicylates  in  a  majority  of  cases.  In  those  cases  in 
which  the  attack  was  not  aborted,  suppuration  seemed 
to  be  very  much  hastened.  The  form  in  which  the 
remedy  was  administered  was  as  follows : 

5.  Sodae  salicylatis 3  iij. 

Aquse 5  vj. 

M.     Sig. — One  tablespoonful  every  two  hours. 

Last  spring  Dr.  Barker  suggested  to  me  the  value  of 
bicarbonate  of  soda  locally  applied.  The  soda  is  to  be 
taken  up  on  the  moistened  finger  and  plastered  over  the 
inflamed  surface  every  ten  or  fifteen  minutes.  I  have 
since  then  made  use  of  this  remedy  in  connection  with 
the  salicylates,  and  in  one  or  two  cases  its  action  has 
been  most  gratifying.  I  am  not  prepared,  however,  to 
abandon  the  use  of  salicylates  in  favor  of  the  soda.  In 
several  cases  also  in  which  the  quinsy  habit  has  existed 
I  have  given  the  above  prescription,  with  directions  to 
commence  its  use  immediately  upon  experiencing  any 
symptoms  of  these  attacks.  These  were  cases  in  private 
practice.  In  no  one  of  these  cases  has  there  been  an 
attack  of  the  disease.  If  the  attack  is  not  aborted  by 
medication,  it  seems  to  me  that  it  is  of  importance  to  us 
to  recognize  and  treat  the  disease,  as  far  as  the  local  pro- 
cess is  concerned,  as  an  abscess  in  any  other  portion  of 
the  body.  In  other  words,  to  treat  it  on  general  surgi- 
cal principles.  I  think  that  the  importance  of  introduc- 
ing the  finger  into  the  fauces  is  not  sufficiently  recog- 
nized. No  case — no  case  of  quinsy,  certainly — should 
ever  be  treated  without  it.  By  introducing  the  finger  into 
the  fauces,  the  condition  and  location  of  the  phlegnion 
can  be  determined,  and  the  occurrence  of  suppuration 
and  the  proper  point  at  which  to  introduce  a  bistoury 
recognized.  In  this  manner  the  treatment  of  a  quinsy 
becomes  a  very  simple  matter,  and  does  away  with  the 
use  of  gargles,  inhalations,  sprays,  fomentations,  etc., 
which  oftentimes  add  to  the  discomfort  of  the  patient 
rather  than  to  his  relief. 

In  conclusion,  I  have  only  to  say  that  if  I  have 
brought  forward  any  suggestions  whidi  are  at  variance 
with  old   established   teaching,  they  are  offered  very 


modestly,  but  still  as  convictions  which  have  been  the 
result  of  a  somewhat  large  experience.  In  acting  upon 
them  I  am  confident  that  I  have  obtained  better  results 
in  the  treatment  of  throat  diseases  than  in  following  the 
older  doctors. 

TWO  CASES  OF  NEURECTOMY  FOR  THE  RE. 
LIEF  OF  FACIAL  NEURALGIA. 

By  GEORGE  R.  FOWLER,  M.D., 

8UKGBON  TO  ST.  UAXY's  CBNKSAL  HOSPITAL,  BSOOKLYM,  K.  Y. 

The  two  following  cases  arc  deemed  by  me  of  sufficient 
importance  to  warrant  their  publication,  inasmuch  as 
they  illustrate  the  two  most  common  forms  of  nenralgia 
of  the  face  and  the  complete  relief  afforded,  in  otherwise 
most  intractable  cases,  by  the  resources  of  operative  sur- 
gical  art. 

Case  I. — Mrs.  M.  L applied  to  me  in  Januaiy, 

1883,  for  the  relief  of  a  most  violent  and  prolonged  neu- 
ralgia,  referred  to  the  area  of  distribution  of  the  frontal 
division  of  the  ophthalmic  or  first  portion  of  the  fifth 
ner\'e.  She  had  suflfered  more  or  less  for  several  yean 
with  milder  attacks  in  the  same  region,  but  the  present 
attack  had  proven  so  severe  and  persistent,  despite 
every  therapeutical  measure,  that  in  sheer  desperation 
she  consented  to  submit  to  any  plan  of  treatment  which 
held  out  the  slightest  hope  of  relief.  When  she  came 
under  my  care  she  had  not  had  the  slightest  remissbn 
of  the  pain  for  full  three  weeks.  Even  opiates,  unless 
pushed  to  the  point  of  dangerous  narcosis,  failed  to 
mitigate  the  pain.  The  conjunctiva  upon  the  affected 
side  was  injected,  ptosis  was  marked,  and  the  lachrymal 
secretion  flowed  copiously  upon  attempts  being  made  to 
raise  the  eyelid.  There  was  intense  tenderness  over  the 
point  of  emergence  of  the  supra-orbital  nerve  from  the 
foramen. 

On  February  4,  1884, 1  operated  by  Lienhart's  method 
as  follows :  An  incision  was  made  along  the  upper  mar- 
gin of  the  left  orbit,  and  in  a  direction  parallel  to  the 
same  directly  down  to  the  bone.  The  tarsal  cartilage 
was  separated  upon  a  director.  The  supra-orbital  nerve 
now  came  into  sight,  and  by  keeping  the  levator  pal- 
pebrar,  as  well  as  the  other  contents  of  the  orbit  waft, 
depressed  by  a  spatula,  was  traced  back  to  the  point 
where  both  it  and  the  supra-trochlear  branch  are  given 
oflf  from  the  frontal  nerve ;  beyond  which  point,  after 
separating  the  trunk  from  its  accompanying  artery,  it 
was  severed  By  means  of  a  pair  of  stout  scissors  the 
fibrous  bridge  which  binds  down  the  nerve  as  it  ap- 
proaches the  foramen  was  broken  down,  the  nerve  drawn 
out,  and  by  retracting  the  upper  lip  of  the  horizontal 
incision,  branches  of  the  nerve  distributed  to  the  fore- 
head were  traced  and  dissected  out.  The  supra-trochlear 
branch  was  divided  at  the  point  where  it  comes  upward 
toward  the  pulley  of  the  superior  oblique  muscle.  The 
wound  was  irrigated  with  Koch's  solution  (mercuric  bi- 
chloride, I  to  1,000),  its  edges  approximated  by  horse-hair 
sutures,  and  a  naphthalinated  cotton  dressing  applied. 

The  after-history  of  this  case  is  entirely  uneventfiiL 
The  wound  pursued  an  aseptic  course,  occupying  lesS: 
than  a  week  in  healing,  and  the  neuralgia  disappeared  at 
once.  Up  to  the  present  time,  six  months  after  the 
operation,  there  has  been  no  return  of  the  trouble,  and  a 
cure  may  confidently  be  asserted  as  having  been  accom- 
plished. 

Case  IL— A.  V ,  aged  fifty-three,  German.    This 

patient  applied  to  me  in  March,  1884,  for  relief  His 
neuralgia  was  of  the  variety  known  as  tic  douloureux,  and 
was  of  three  months'  standing;  for  the  last  six  weeks  of 
this  time  he  had  been  deprived  almost  entirely  of  sleeps 
suffering  all  the  while  the  most  intense  and  agonizing 
torture.  He  had  been  treated  by  a  number  of  physiciaiis, 
and  all  the  usual  remedies  had  been  prescribed  for  him,* 
without,  however,  affording  him  any  relief.  The  pain 
extended  through  the  branches  of  the  second  division  of 
the  fifth  nerve,  upon  the  left  side ;  hyperaesthesia  of  the 


October  4,  1834.} 


THE  MEDICAL  RECORD. 


369 


whole  surface  of  afifected  aresl  existed,  as  well  as  a  most 
exquisite  sensitiveness  of  the  gum  and  teeth  of  the  upper 
jaw  of  that  side.  The  slightest  touch  of  the  integument 
or  an  attempt  at  taking  food  brought  on  a  paroxysm  of 
JDcreased  pain,  with  twitching  of  die  left  facial  muscles. 
The  pain  was  more  or  less  constant  during  the  intervals 
of  freedom  from  twitching,  but  when  the  pain  and  "  tic  " 
were  conjoined  the  agony  was  painful  to  witness. 

On  March  20,  1884,  I  performed  the  following  modifi- 
cation of  the  operation  first  devised  and  practised  by 
Camochan,  of  New  York :  Ether  having  been  administered, 
a  curvilinear  incision  was  made  parallel  to  and  slightly 
below  the  inferior  orbital  margin,  from  the  inner  to  the 
outer  angle  of  the  eye.  This  was^  carried  directly  down 
to  the  bone  and  the  flap  dissected  upward  until  the  edge  of 
the  infra-orbital  ridge  was  reached.  The  leash  of  nerves 
constituting  the  branches  of  the  infra-orbital  after  it 
leaves  the  foramen  was  now  dissected  from  the  under 
surface  of  this  flap.  The  tissues  covering  the  anterior  sur- 
face of  the  superior  maxillary  bone  were  next  detached 
and  drawn  downward  by  a  retractor  and  there  held  by  an 
assistant.  A  trephine  flve-eighths  of  an  inch  in  diameter 
was  now  applied  in  such  a  way  that  its  point  punctured 
the  antrum  of  Highmore  upon  a  vertical  line  running 
directly  downward  from  the  infra-orbital  foramen,  while 
its  rim  or  cutting  edge  -slightly  overlapped  the  foramen 
itself.  By  following  this  rule  in  the  application  of  the 
trephine,  it  was  found  that  all  of  the  available  space 
possible  was  gained  for  operating.  The  removal  of  a 
button  of  bone  from  the  anterior  wall  of  the  antrum  hav- 
ing been  accomplished,  the  patient  was  lifted  from  the 
operating  table  to  a  chair  and  placed  in  a  sitting  position 
with  his  back  to  a  window  ;  a  reflecting  mirror  upon  my 
forehead  furnished  the  necessary  light  for  the  performance 
of  the  rest  of  the  operation.  The  posterior  wall  of  the 
antrum  was  now  perforated  by  a  trephine  half  an  inch 
in  diameter.  In  using  this  latter  the  centre- pin  was  with- 
drawn prior  to  its  application,  the  converging  surfaces  of 
the  cavity  being  found  sufficient  to  support  the  instru- 
ment, and  the  danger  of  unwittingly  thnisting  the  pin 
into  the  spheno-manllary  fossa  avoided. 

Upon  perforating  the  postenor  wall  of  the  antrum,  the 
spheno-maxillary  fossa,  together  with  its  contents,  was 
brought  into  view.  With  a  small  chisel  the  infra-orbital 
canal  was  opened  and  broken  down  so  as  to  release  the 
netye  and  its  accompan)dng  arter>',  and  tracing  the  nerve 
rapidly  back  to  the  point  where  it  enters  the  orbit,  with 
a  pair  of  small  double-curved  scissors  section  of  the 
trunk  of  the  superior  maxillary  nerve  was  made  beyond 
the  point  where  it  joins  the  ganglion  of  Meckel.  The  or- 
bital, spheno-palatine,  and  inferior  dental  branches  being 
divided,  the  ganglion  and  nerve-tnink  were  together 
drawn  out.  A  smart  hemorrhage  from  that  portion  of 
the  internal  maxillary  artery  contained  in  the  spheno-max- 
illary fossa  now  occurred,  but  it  was  readily  controlled 
by  a  small  piece  of  compressed  sponge  attached  to  a 
stout  thread  and  crowded  into  the  fossa.  This  latter  was 
left  in  position  in  order  to  guard  against  the  bleeding. 
The  parts  were  irrigated  with  Koch's  solution,  the  exter- 
nal wound  drawn  together  by  a  few  horse-hair  sutures, 
an  opening  being  led  at  the  most  dependent  angle  for 
drainage,  as  well  as  to  facilitate  the  withdrawal  of  the 
compressed  sponge,  and  a  dressing  of  naphthalinated 
cotton  applied. 

The  next  day  the  sponge  was  removed.  Daily  irriga- 
tions with  Koch's  solution  and  dressing  with  naphthalin- 
ated cotton  were  practised.  The  wound  healed  slowly, 
owing  to  the  impracticability  of  keeping  it  in  an  aseptic  con- 
dition, and  a  month  elapsed  before  it  had  entirely  closed. 
For  the  first  few  hours  after  the  operation  the  patient 
complained  of  wandering  pains  over  the  whole  left  side 
of  the  face,  but  the  "  tic  "  had  disappeared  entirely,  and 
m  twenty-four  hours  he  expressed  himself  as  being  per- 
fectly free  from  pain  ;  this  improvement  continued,  and 
no  recurrence  of  the  pain  took  place.  A  slight  depres- 
sion exists  at  the  site  of  removal  of  the  button  of  bone. 


Remarks, — Fortunately,  as  a  matter  of  clinical  expe- 
rience, intractable  and  persistent  facial  neuralgia  requir- 
ing operative  measures  for  its  relief  is  comparatively 
rare.  It  is  a  matter  of  congratulation,  likevnise,  that  it 
occurs,  in  the  vast  majority  of  cases,  in  nerves  purely 
sensory,  admitting  of  neurotomy  or  neurectomy  with- 
out destruction  of  important  functions.  There  can  be  no 
question  as  to  the  propriety  of  operating  in  these  desper- 
ate cases,  for  a  sufficiently  large  number  are  on  record 
in  which  relief  has  been  afforded  to  attest  the  value  of 
the  proceeding.  In  the  choice  of  operation  preference 
should  always  be  given  to  neurectomy  rather  than  to 
neurotomy,  for  the  reason  that  ex]>erience  proves  that 
almost  invariably  the  pain  returns  after  the  latter  pro- 
cedure, and  even  in  some  instances  has  been  at^gravated 
after  a  lapse  of  time,  owing  probably  to  the  nerve  be- 
coming involved  in  the  cicatrix  at  the  site  of  operation. 
On  the  other  hand,  neurectomy  gives  a  relief  more  or 
less  decided  and  lasting. 

As  to  the  origin  of  these  severe  fomis  of  neiualgia  of 
the  facial  nerves,  I  can  offer  but  little  \  nor  can  it  be 
said  that  a  positive  opinion  can  be  advanced  in  a  given 
case  as  to  whether  the  neuralgia  is  of  central  or  per- 
ipheral origin.  Fortunately,  however,  either  variety  is 
benefited,  though  not  equally  so,  by  neurectomy*  In 
the  central  variety,  there  can  be  no  doubt  that  the 
paroxysms  of  severe  pain  are  induced  by  the  application 
of  stimuli  to  the  periphery,  and  that  a  removal  of  the 
nerve- trunk  and  its  branches  as  far  as  practicable  de- 
stroys  the  medium  by  means  of  which  these  stimuli  are 
conducted  centripetally.  The  suspension  of  the  excit- 
ability of  the  nerve-centre,  even  though  temporarily,  is 
of  benefit  by  fulfilling  the  first  indication  in  the  treatment, 
namely,  rest  and  freedom  from  irritation.  Further,  the 
reflected  or  irradiated  pains,  of  themselves  sources  of 
much  siiflfering,  are  relieved  by  quieting  the  central  ex- 
citability. 

Where  the  neuralgia  is  indubitably  of  peripheral  origin, 
as  for  instance  in  those  cases  where  a  portion  of  a  nerve- 
trunk  or  its  branches  are  involved  in  a  cicatrix,  or  a 
neuroma  has  developed  upon  the  same,  a  cure  may  be 
confidently  promised  if  neurectomy  be  resorted  to.  Here 
removal  of  the  nerve-trunk  as  far  away  from  the  original 
point  of  irritation  as  is  practicable  is  advised.  Every 
effort  should  be  made  to  promote  rapid  healing  after 
operation,  for  the  reason  that  the  greater  the  amount  of 
connective-tissue  proliferation  and  formation  of  cicatri- 
cial tissue  about  the  nerve-stump,  the  greater  the  chance 
of  the  developing  therein  of  nerve-fibres,  these  communis 
eating  with  or  springing  from  the  nerve-stump,  and  sub- 
sequently dragging  upon  the  latter  and  becoming  a  re- 
newed source  of  irritation.  The  antiseptic  method  of 
operating  is,  therefore,  to  be  commended  as  being  most 
likely  to  accomplish  the  best  possible  results. 


Physio-Medicalism. — ^A  correspondent  asks  for  infor- 
mation regarding  "physio-medical"  colleges  and  practi- 
tioners. So  far  as  we  can  learn,  physio- medicalism  is  an 
"  ism  "  which  flourishes  only  in  Ohio  and  Indiana,  There 
have  been  in  Cincinnati  a  Physio-Medical  College  and  a 
Physio-Eclectic  Medical  College,  both  of  which  institu- 
tions, like  the  good,  died  youn^.  There  is  now  in  Cin- 
cinnati The  Physio-Medical  Institute^  which  has  been  in 
existence  since  1877,  and  which  graduates  a  dozen  stu- 
dents every  year.  Its  catalogue  requirements  are  as  high 
as  those  of  most  regular  colleges,  but  it  graduates  a  higher 
per  cent,  of  students  upon  matriculants  than  the  average. 
There  is  also  a  Physio-Medical  College  in  Indianapolis, 
Ind.,  which  was  also  founded  in  1877,  and  which  also  grad- 
uates a  very  high  per  cent,  of  students.  What  the  peculiar 
tenets  of  physio-medicalism  are  we  do  not  know.  There 
cannot  be  many  over  a  hundred  legitimate  graduates  in 
this  specialty,  and  its  existence  is  of  small  importance. 
The  extinct  institutions  were  probably  merely  advertising 
dodges  for  a  few  quacks» 


37^ 


THE  MEDICAL  RECORD. 


H^ 


[October  4, 1884, 


LAPAROMYOMOTOMY. 

Rei»ort  of  Two  Cases  Successfully  Treated  in  a 

General  Hospital. 

By  lewis  ^.  STIMSON,  M.D., 

PROFBS8OR  OP  CLINICAL  SUXGEKY  IN  THK    MEDICAL    DBPARTMKNT    OP   TUB    UNI- 
VBKSITY  OP  TBB  QTY  OP  NBW  YOKK. 

I  OFFER  the  following  brief  history  of  two  cases  of  suc- 
cessful removal  of  the  uterus  and  ovaries  by  abdominal 
section  as  a  contribution  to  a  subject  which  is  now  re- 
ceiving much  attention.  A  point  of  special  interest  is 
the  fact  that  both  were  treated  in  the  common  ward  of  a 
general  hospital.  Each  was  a  case  of  multiple  fibromata 
of  the  uterus. 

The  antiseptic  precautions  consisted  in  thorough  disin- 
fection by  the  bichloride  of  mercury  of  the  hands  of  the 
surgeons,  of  all  sponges  and  cloths,  and  of  the  wound  oi 
the  abdominal  parieties  by  irrigation.  The  instruments 
were  kept  in  a  strong  solution  of  carbolic  acid,  and 
the  sponges  that  were  introduced  into  the  abdominal 
cavity  were  first  purified  by  immersion  in  the  [bichloride 
solution  and  kept  during  the  operation  in  a  hot  solu- 
tion of  carbolic  acid.  The  pedicle  was  secured  by  trans- 
fixion and  ligation  with  india-rubber  coed,  and  treated 
by  the  extra-peritoneal  method.  The  ligatures  came 
away  on  the  tenth  and  seventeenth  days  respectively. 
The  external  wound  was  kept  covered  with  iodoform  and 
dressings  of  borated  cotton  and  iodoform  or  carbolized 
gauze.  In  each  case  the  final  cicatrization  of  the  wound 
was  slow. 

In  the  first  case,  the  stump  of  the  uterus  promptly 
sank  back  to  its  original  position ;  in  the  second,  it  re- 
mained for. several  weeks  drawn  high  up  and  firmly  ad- 
herent to  the  anterior  abdominal  wall.  At  no  time  did 
the  symptoms  in  either  case  cause  more  anxiety  than  that 
which  would  be  naturally  associated  with  the  operation. 
In  both  cases  I  was  greatly  aided  by  the  advice  and  as- 
sistance of  my  friend  and  colleague  Professor  Wm.  M, 
Polk. 

Case  I. — Effie  V ,  colored,  about  thirty  years  of 

age,  was  sent  to  me  for  treatment  from  Bedminster,  N. 
J.  I  admitted  her  to  the  Presbyterian  Hospital  early  in 
May,  1884. 

She  bore  a  child  ten  years  ago.  For  the  eighteen 
months  preceding  her  admission  to  the  hospital  she  had 
been  troubled  by  an  abdominal  tumor,  which  caused  much 
pain,  entirely  prevented  her  from  working,  and  was  ac- 
companied by  profuse  menorrhagia.  Her  courses  were 
very  profuse. 

There  was  a  hard,  irregular  tumor  within  the  abdominal 
cavity,  extending  from  a  little  to  the  right  of  the  median 
line  in  the  hypogastrium  upward  and  to  the  left  to  a 
point  above  the  level  of  the  umbilicus,  and  protruding 
into  the  vagina  so  as  to  force  the  uterus  upward  and 
backward  almost  beyond  the  reach  of  the  finger.  The 
tumor  Was  slightly  movable  at  first,  and  changed  its  po- 
sition downward  and  to  the  right  and  became  more 
movable  while  the  patient  was  under  observation.  The 
cavity  of  the  uterus  was  four  and  one-half  inches  long. 
The  diagnosis  was  "  pedunculated  fibroid  of  the  anterior 
wall  of  the  uterus,  with  enlargement  of  the  uterus  by 
intra-mural  fibroids." 

May  24th. — Operation.  The  surface  of  the  abdomen 
was  washed  with  soap  and  water  and  then  with  the  bi- 
chloride solution,  the  limbs  and  upper  portion  of  the 
trunk  wrapped  in  blankets,  and  the  lower  portion  of  the 
trunk  wrapped  in  a  rubber  sheet  in  which  an  oval  hole 
had  been  cut  at  the  part  corresponding  to  the  field  of 
operation.  Over  this  sheet  were  placed  cloths  wet  with 
the  bichloride  solution.  An  incision  was  made  in  the 
median  line  from  a  point  a  little  below  the  umbilicus  to 
the  pubes,  and  all  bleeding  arrested  before  the  peritoneum 
was  divided.  After  division  of  the  peritoneum  the  hand 
was  introduced  into  the  cavity,  and  with  some  difficulty 
the  pedunculated  tumor,  which  had  a  long  pedicle,  was 
turned  out.  The  left  ovary  was  found  to  lie  at  some  dis- 
tance from  the  uterus,  and  a  double  silk  ligature  was 


passed  through  the  broad  ligament  below  the  pampim. 
form  plexus  by  means  of  an  ivory  pin,  and  tied  on  each  side 
of  the  ovary;  the  latter  was  then  cut  ofL  The  right 
ovary  lay  close  against  the  uterus,  and  as  it  was  thoi^ght 
it  could  not  be  separately  removed  without  risk  of 
hemorrhage,  and  as  the  uterus  was  found  to  be  studded 
with  tumors,  the  latter  was  drawn  forcibly  upward,  and 
its  neck,  which  was  long  and  free,  was  transfixed  from 
before  backward  with  the  ivory  pin,  and  a  double  india- 
rubber  cord  four  millimetres  in  diameter  drawn  through 
and  tied  around  each  half.  On  the  left  side  the  rubber 
ligature  passed  just  below  the  ligature  that  had  been 
placed  under  the  ovary  ;  on  the  right  side  it  passed  out- 
side the  ovary  and  embraced  the  entire  thickness  of  the 
broad  ligament.  Each  ligature  was  drawn  very  tight  and 
secured  by  tying  it  in  a  single  knot  and  fastening  the  ends 
together  close  to  the  knot  by  a  loop  of  silk.  The  uterus 
was  then  cut  off  and  the  stump  brought  to  the  lower  angle 
of  the  abdominal  wound  and  transfixed  with  two  long  pins 
close  to  the  ligatures  in  the  distal  side.  Very  liitie  bleed- 
ing took  place  from  the  punctures  made  in  transfixion, 
and  a  sponge  passed  into  Douglas'  cul-de-sac  brou^t 
out  only  a  small  clot  of  blood. 

The  peritoneum,  the  aponeurotic-muscular  layer,  and 
the  skin  were  each  united  with  a  continuous  catgut  suture, 
and  three  silver  wire  and  button  sutures,  not  including  the 
entire  thickness  of  the  wall,  applied  to  bear  the  strain.  A 
decalcified  bone  drain  was  placed  in  the  parietal  wound 
between  the  skin  and  peritoneum,  extending  from  the 
upper  angle  of  the  wound  to  the  stump.  Iodoform, 
gauze,  body-bandage. 

The  pedunculated  tumor  was  flattened,  and  its  pedicle 
ran  from  the  centre  of  the  flattened  surface  ;  it  measured 
four  by  six  inches  across  the  top,  and  three  inches  from 
the  pedicle  to  the  upper  surface ;  the  pedicle  was  two 
inches  long,  one  and  a  half  inch  wide,  and  one-fourth 
inch  thick  when  compressed  between  the  fingers.  The 
uterus  was  irregular  in  form,  with  one  small  (one  inch) 
pedunculated  fibroid  and  many  intra-mural  ones;  it 
measured  four  inches  across  the  fundus,  and  the  length 
of  the  portion  removed  was  the  same. 

May  25th. — Temperature,  loo^^  Slight  abdominal 
pain.  Ordered  morphine,  and  an  ice-water  coil  on  each 
side  of  the  abdomen.  The  wound  had  oozed  freely,  but 
was  then  dry.  In  order  to  make  the  application  of  the 
ice-water  coil  more  efficient,  the  gauze  dressings  were 
removed,  and  a  compress  kept  wet  with  the  bichloride 
solurion  substituted. 

May  26th. — Temperature,  looj^. 

May  27th. — Removed  drainage-tube  and  button  su- 
tures. 

May  29th. — Temperature,  984^°.     Discontinued  coD. 

June  2d. — Removed  the  rubber  ligatures,  which  were 
lying  loose,  and  the  slough  of  the  stump.  This  left  a 
good-sized  suppurating  cavity,  at  the  bottom  of  which 
was  an  opening  into  which  a  probe  passed  easily  to  the 
depth  of  two  iriches  below  the  surface  of  the  skin.  It 
was  apparently  formed  by  the  sinking  of  the  stump  after 
it  had  become  adherent  to  the  peritoneum  lining  of  the 
anterior  abdominal  wall.  Dressed  the  wound  with  iodo- 
form and  dry  absorbent  cotton,  the  latter  to  be  fre- 
quently changed. 

June  9th. — ^The  cavity  is  slowly  filling,  but  the  pouch 
at  the  bottom  remains  unchanged,  except  that  its  orifice 
is  smaller ;  it  is  about  one  inch  deep  and  one-third  inch 
in  diameter. 

June  1 6th, — ^Wound  is  slowly  contracting;  pouch  still 
one  inch  deep. 

June  23d. — Pouch  no  longer  recognizable;  wound 
nearly  flat. 

July  ist. — Patient  sits  up ;  the  neck  of  the  uterus  can 
be  readily  felt  high  in  the  vagina. 

July  1 2th. — Wound  entirely  healed.     Discharged. 

Case  II. — Mrs.  F ,  forty  years  of  age,  entered  the 

Presbyterian  Hospital  June  17,   1884.    She  had  been 
suffering  for  eight  and  a  half  months  with  a  tumor  in  the 


w 


October  4,  1884.] 


THE  MEDICAL  RECORD. 


37^ 


lower  part  of  the  abdomen,  profuse  menorrhagia,  and 
pain.  For  four  months  of  this  time  she  had  continuous 
pain  and  fever,  and  she  still  sufifers  so  much  that,  al- 
though fully  aware  of  the  risks  of  an  operation,  she  de- 
sires to  undergo  it  in  the  hope  of  relief.  The  tumor 
occupies  the  lower  portion  of  the  abdominal  cavity,  ex- 
tending up  to  the  umbilicus,  is  hard,  irregular,  and  mov- 
able, and  projects  into  the  vagina,  crowding  the  uterus 
so  far  back  and  upward  that  the  os  can  barely  be  reached 
with  the  finger. 

Diagnosis. — Intra-mural  fibroids,  probably  with  exten- 
sive adhesions. 

July  8th. — Operation.  This  was  conducted  as  in  the 
preceding  case.  The  uterus  was  found  studded  with  in- 
tra-mural and  sub-peritoneal  fibroids,  and  the  peritoneum 
covering  it  doubled  by  a  soft,  very  vascular  layer  adher- 
ent to  the  rectum  in  bands.  The  right  ovary  was  free 
and  quite  distant  from  the  uterus ;  the  left  ovary  was  quite 
closely  attached  to  the  sigmoid  flexure,  and  its  tube  was 
adherent  to  the  rectum  and  sacral  wall  and  dilated  to 
one  inch  in  diameter.  The  adhesions  to  the  rectum 
were  divided  between  double  catgut  ligatures,  and  the 
ovaries  freed  by  transfixing  and  cutting  between  double 
silk  ligatures.  In  the  anterior  wall  of  the  uterus,  low 
down,  was  a  large  globular  fibroid,  over  the  lower  por- 
tion of  which  the  bladder  was  broadly  spread  out.  I 
made  a  transverse  cut  through  the  peritoneum  above  the 
reflection  of  the  bladder,  stripped  the  latter  away  firom 
the  uterus  with  the  finger,  passed  a  double  rubber  cord 
through  the  cervix  and  included  fibroid  tissue,  and  tied  it. 
As  it  seemed  inadequate  properly  to  constrict  the  tissues 
embraced  in  its  loop,  I  passed  a  second  larger  cord 
through  the  same  puncture  and  tied  with  both,  then  cut 
away  the  bulk  of  the  mass  and  enucleated  from  the 
stomp  the  remaining  fibroids  and  portions  of  fibroids. 
The  parietal  ligature  beyond  the  left  ovary  meanwhile 
had  dipped  and  some  bleeding  followed,  which  was  ar- 
rested by  passing  an  armed  needle  through  the  mass  of 
divided  vessels  close  to  the  sigmoid  flexure  and  tying  on 
both  sidqs.  The  oozing  in  the  pouch  made  by  stripping 
up  the  bladder  was  quite  free,  and  was  finally  arrested 
by  the  actual  cautery  ;  this  pouch  was  drained  by  a  rub- 
ber tube,  its  surface  dusted  with  iodoform,  and  its  mouth 
closed  in  great  part  by  stitching  the  peritoneum  to- 
gether. The  stump  was  brought  to  the  lower  porrion  of 
the  wound  and  transfixed  with  four  long  pins.  The  peri- 
toneal portion  of  the  abdominal  wound  was  closed  by  a 
continuous  catgut  suture,  the  musculo-aponeurotic  layer 
hy  interrupted  catgut  sutures,  and  the  skin  by  interrupted 
cat^t  and  two  silver  sutures.  A  long  decalcified  bone 
drainage-tube  was  passed  into  Douglas'  cul-de-sac,  and 
the  incision  and  stump  dusted  with  iodoform  and  dressed 
with  iodoform  gauze,  borated  cotton,  and  a  body-band- 
age.    Morphine  ordered. 

July  9th. — ^Temperature  rose  gradually  to  102°  in 
the  morning,  and  sank  to  ioof°  in  the  afternoon. 
Changed  dressing  and  removed  the  bone  drainage-tube. 
The  deeper  layers  of  the  dressing  were  saturated  with  a 
dark,  thin  discharge.  Irrigation  coil  applied  on  each  side. 
July  loth. — ^Temperature,  .loof**.  Occasional  pain, 
otherwise  comfortable. 

July  nth. — Much  nausea;  removed  one  inch  of  the 
nibber  drainage-tube ;  dressing  dry  except  for  a  small 
stain  over  the  tube ;  temperature,  99°  to  101° ;  morphine 
discontinued. 

July  1 2th. — ^Temperature  has  remained  below  100**; 
the  only  complaint  is  of  the  nausea  and  of  pain  caused 
by  vomiting. 

July  15th. — Changed  dressing  and  removed  the  tube  ; 
temperature  still  below  100® ;  some  little  nausea. 

July  1 6th. — Pressure  caused  about  two  ounces  of  pus 
to  flow  out  beside  the  stump  and  from  the  upper  angle 
of  the  wound. 

July  24th. — Stump  came  away  this  morning  ;  the  liga- 
Ctirss  had  not  cut  through,  but  remained  fast  on  the 
porion  that  sloughed  off,  the  slough  extending  about  a 


quarter  of  an  inch  beyond  them.  The  cavity  is  an  inch 
deep  and  its  bottom  flat  and  solid  ;  the  adjoining  skin 
has  turned  inward,  especially  on  the  left  side,  and  united 
with  the  surface  of  the  wound, 

July  ^6th. — After  a  severe  fit  of  vomiting  this  morning 
free  bleeding  took  place  from  the  deeper  part  of  the 
wound ;  it  was  arrested  by  lightly  touching  the  bleeding 
point  with  the  cautery, 

August  14th. — ^The  patient  has  been  doing  Ytry  w^Il, 
except  for  occasional  nausea*  The  wound  is  deeply 
retracted;  the  skin  on  the  left  side  extends  to  the  bottom; 
on  the  other  side  is  a  flat  granulating  surface  about  one 
and  a  half  inch  long  and  a  quarter  of  an  inch  wide. 

I  failed  to  touch  the  cervix  in  vaginal  examination* 
The  abdominal  wall  at  the  wound  is  not  movable  upon 
the  underlying  parts  ;  some  tenderness  on  pressure  on 
each  side  above  the  wound ;  told  to  sit  up. 

August  29th. — ^The  wound  has  become  level  with  the 
surface  of  the  abdomen  by  the  rising  of  the  retracted 
skin,  and  is  cicatrized  at  its  centre.  The  cervix  is  lower 
and  can  now  be  readily  felt  in  the  vagina. 

At  intervals  of  about  a  week  the  patient  has  had 
attacks  of  nausea  and  pain  in  the  lower  |?art  of  the 
abdomen,  which  have  always  ceased  after  a  free  evacua- 
tion of  the  bowels  has  been  obtained  by  enema. 

September  nth. — Patient  left  hospital  well  and  **  feel- 
ing better  than  in  years,"  There  has  been  no  recurrence 
of  the  nausea  and  pain  in  the  abdomen  since  the  latter 
part  of  August. 

I  chose  the  extra-peritoneal  method  of  treating  the 
pedicle  because  I  deemed  the  consequent  delay  In  the 
final  healing  of  the  external  wound  of  no  importance 
when  compared  with  the  security  which  the  method 
gives  against  complications  arising  from  retention  of 
pus  or  decomposition  of  the  portion  of  the  pedicle  em- 
braced in  the  ligature.  It  may  be  that  the  first  of  these 
two  cases  would  have  done  as  well  if  the  pedicle  had 
been  allowed  to  drop  back  into  the  abdominal  cavity, 
but  it  could  hardly  have  done  any  better.  By  the  ninth 
day  the  ligatures  had  fallen,  the  abdominal  cavity  was 
closed,  and  there  remained  only  the  granulating  wound 
of  the  anterior  abdominal  wall,  and  this  soon  cicatrized. 
With  intra-peritoneal  treatment  of  the  pedicle  the  healing 
of  the  external  wound  may  be  equally  delayed,  and  even 
when  this  healing  takes  place  most  promptly  the  patient 
gains  but  little  in  time  or  in  security,  for  the  risks  or 
discomforts  arising  from  the  small  unhealed  surface  are 
trifling,  and  a  due  regard  for  the  safety  of  the  internal 
cicatrices  would  compel  an  equally  prolonged  confine- 
ment to  the  bed  even  if  the  external  wound  were  healed. 

In  the  second  case  I  am  convinced  that  the  intra 
peritoneal  method  would  have  placed  the  patient's  life  in 
extreme  peril.  The  cervix  was  itself  occupied  by  tumors, 
and  through  two  of  these  the  ligature  had  to  be  passed. 
Separation  took  place,  not  in  the  plane  constricted  by 
the  ligature,  but  at  a  little  distance  on  its  proximal  side, 
apparently  at  the  limit  of  the  transfixed  tumors,  and 
when  the  ligatures  came  away  (on  the  seventeenth  day) 
they  still  firmly  held  the  slough.  It  is  extremely  Im- 
probable that  such  an  occurrence  could  have  taken  place 
within  the  abdominal  cavity  without  provoking  suppura- 
tion, and  for  the  pus  so  formed  there  would  have  been 
no  outlet  except  such  as  might  have  spontaneously 
formed.  The  formation  and  retention  of  that  pus  and 
the  possible  decomposition  of  the  slough  would  have 
been  most  dangerous  complications. 

The  only  serious  objection  to  the  extra-peritoneal 
method  which  I  foresaw  was  the  possible  interference  of 
the  pedicle  with  the  subsequent  distention  of  the  bladder. 
I  expected  that  the  cervix  would  remain  attached  to  the 
anterior  abdominal  wall  closely  enough  to  compress  the 
bladder  against  the  pubes  and  allow  of  its  dilatation 
only  on  each  side.  This  anticipation  was  not  realized. 
In  neither  case  did  the  patient  find  it  difficult  to  retain 
her  urine  for  the  usual  length  of  time,  and  in  each  the 


372 


THE  MEDICAL  RECORD. 


[October  4,  1884^ 


cervix  sank  back  (promptly  in  the  first  case,  much  later 
in  the  second)  to'  its  former  place  in  the  pelvis.  Ap- 
parently this  was  accomplished  by  the  stretching  or  slid- 
ing of  the  peritoneum  after  adhesion  had  taken  place 
between  its  confronted  surfaces ;  and  in  the  first  case,  in 
.which  it  was  found  to  have  occurred  when  the  ligatures 
fell,  a  deep  pouch  like  a  glove-finger  was  formed  and 
easily  demonstrated  at  the  bottom  of  the  wound.  The 
^effect  of  this  occurrence  is  to  place  the  parts  in  what  is 
practically  the  same  condition  as  that  in  which  they  are 
left  by  the  intra-peritoneal  method  of  treating  the  stump, 
and  thus  to  restrict  the  differences  between-  the  two 
methods  to  those  existing  during  the  process  of  repair  of 
the  wound.  Those  differences  appear  to  make  the  extra- 
peritoneal method  much  the  saier,  for  in  it  there  is  no 
possibility  of  the  inclusion  of  a  decomposing  slough  or  of 
the  retention  of  pus  that  has  formed  about  the  ligature, 
and  if  hemorrhage  occurs  through  the  slipping  of  the  liga- 
ture, as  has  occasionally  happened  and  with  fatal  results, 
it  is  at  once  detected  and  is  accessible  to  treatment. 


ANTISEPTIC  MIDWIFERY. 
By  a.  C.  page,  M.D., 

TSUKO,   N.  S. 

Mr.  President  :  The  object  of  this  writing  is  to  intro- 
duce the  question  of  **  Antiseptic  Midwifery,"  hoping  in 
this  way  to  obtain  the  experiences  of  wiser  and  abler  men, 
so  that  while  I  am  being  taught,  our  younger  brethren 
may  catch  some  useful  hints  to  help  them  over  hard 
places.  At  the  February  meeting  of  the  Colchester 
County  Medical  Association,  Dr.  I.  W.  McDonald,  of 
Londonderry  Iron  Mines,  was  kind  enough  to  give  an  ob- 
ject-lesson; illustrating  the  materials  used  and  the  manner 
of, applying  antiseptic  dressings  in  surgery. 

In  the  discussion  that  followed.  Dr.  Neil  Sutherland,  of 
Spring  Hill  Mines,  called  attention  to  the  importance  of 
antiseptics  in  midwifery  practice,  and  Dr.  McLeod,  of 
Economy,  related  a  case  where,  for  want  of  such  atten- 
tion, he  was  caused  great  inconvenience  and  anxiety, 
he  having,  as  he  supposed,  carried  septic  germs  to  his 
patient  from  a  suppurating  wound  he  had  just  previously 
been  dressing,  with  nearly  fatal  consequences.  I  have 
been  in  the  habit,  from  the  beginning  of  my  practice, 
twenty-eight  years  ago,  of  washing  out  the  vagina  with 
Labarraque*s  solution  in  all  cases  where  the  discharges 
after  confinement  were  offensive,  and  my  attention  was 
called  to  it ;  but  in  many  of  my  cases  I  never  saw  my  pa- 
tient more  than  once  after  delivery,  and  many  not  even 
once.  Of  late,  however,  the  journals  are  teeming  with 
articles  on  this  subject,  and  the  indolent  or  ignorant  are 
being  faithfully  warned  of  the  dangers  by  which  our  pa- 
tients are  surrounded  constantly,  and  in  a  feeble  way 
means  are  pointed  out  having  for  their  end  the  avoid- 
ance of  those  dangers.  Antiseptic  midwifery,  as  well  as 
surgery,  is  based  upon  the  theory  that  the  air  we  breathe, 
by  which  we  are  constantly  encompassed,  and  which  we 
cannot  very  well  get  away  from,  as  well  as  the  water  we 
drink — that  is,  the  few  of  us  who  drink  water — in  fact, 
our  whole  environment,  is  loaded  with  disease -germs, 
ready  at  all  times — but  sometimes  with  more  malignancy 
than  others — to  pounce  upon  the  unwary  or  unsulphur- 
ized,  and  enter  by  any  or  all  avenues,  particularly  by  raw 
or  abraded  surfaces,  into  the  blood,  and  poison  that  pre- 
cious fluid  to  destruction  and  death.  The  puerperal 
woman  seems  to  have  a  peculiar  attraction  for  these 
germs,  and  if  one  of  them  comes  at  all  within  her  reach, 
it  fastens  itself  with  a  death-grip  upon  the  spot  most  fav- 
orable to  the  development  of  its  destructive  power,  not 
only  destroying  her  life,  but  multiplying  itself  till  all  per- 
sons and  all  things  that  have  been  near  her  are  filled 
with  the  same  deadly  influence,  which  they  may  and  do 
distribute,  right  and  left,  killing  as  they  go.  This  is  truly 
a  fearful  fact  to  contemplate,  in  the  face  of  the  other  fact, 
that  the  only  way  known  for  obeying  the  scripture  in- 

1  Read  before  the  Nova  Scotia  Medical  Society. 


junction,  "  Multiply  and  replenish  the  earth,**  is  by  woman 
assuming  the  risk  of  mateniity. 

One  of  the  most  talented  and  successful  practitioners 
and  teachers  of  female  diseases,  whose  reputation  is 
world-wide,  and  whom  all  who  know  honor  and  respect, 
recently  published  in  one  of  the  journals  some  "  prophy- 
lactic measures  which  should  be  adopted  in  all  midwifery 
cases,  whether  they  occur  in  hospital  or  in  private  prac- 
tice."    Listen  to  them : 

"  I.  The  room  in  which  the  confinement  is  to  take 
place  should  have  the  floor,  walls,  and  furniture  thor- 
oughly washed  with  a  ten-per-cent.  solution  of  carbolic 
acid  or  mercuric  bichloride,  i  to  1,000,  and  the  bedstead 
and  mattresses  should  be  sponged  with  the  same  solu- 
tion ;  carpets,  curtains,  and  upholstered  furniture  should 
be  dispensed  with  as  far  as  possible. 

**  2.  The  nurse  and  physician  should  take  care  that  all 
their  clothing,  both  upper  and  under,  be  clean  and  free 
from  exposure  to  the  effluvia  of  any  septic  aflection. 
Should  either  of  them  have  been  exposed  within  a  fort- 
night to  the  effluvia  of  such  affections  as  scarlet  fever, 
typhus,  er}'sipelas,  septicaemia,  or  the  like,  they  should 
change  every  article  of  clothing,  and  bathe  the  entire 
body,  especially  the  hair  and  beard,  with  a  reliable  anti- 
septic solution  ;  that  which  I  prefer  for  this  purpose  is  a 
saturated  solution  of  boracic  acid. 

''3.  As  labor  sets  in,  the  nurse,  having  thoroughly 
washed  her  hands,  cleaned  her  nails  with  a  stifi*  nail- 
brush, and  soaked  them  in  antiseptic  fluid,  should  admin- 
ister to  the  patient  a  warm  vaginsil  injection  of  antiseptic 
character ;  bathe  the  vulva  and  surrounding  parts  freely 
with  the  sartie  ;  repeat  this  every  four  hours  during  labor, 
and  keep  a  napkin  wrung  out  of  the  warm  antiseptic 
fluid  over  the  genital  organs  until  the  birth  of  the  child. 

"4.  Before  the  moment  of  labor  both  doctor  and 
nurse  should  wash  the  hands  thoroughly  with  soap  and 
water,  scrub  the  nails  with  a  stiff"  nail-brush,  and  soak  the 
hands  for  several  minutes  in  a  bichloride  solution,  i  to 
1,000. 

"  5.  The  third  stage  should  be  efficiently  produced ; 
all  portions  of  placenta  and  membranes  removed,  and 
ergot  administered  in  moderate  doses  three  times  a  day, 
and  kept  up  for  at  least  a  week,  for  a  complete  closure  of 
the  uterine  cavity,  expulsion  of  clots,  and  occlusion  of 
the  utero-placental  vessels. 

"6.  The  doctor,  taking  nothing  for  granted,  should,  at 
the  conclusion  of  the  labor,  carefully  examine  the  vulva 
of  the  patient.  If  the  perineum  be  lacerated,  it  should 
be  closed  at  once  by  suture,  and  should  slight  solutions 
of  continuity  be  found  in  the  labia  or  the  vulvar  extrem- 
ity of  the  vagina,  these  should  be  dried  by  pressure  of  a 
linen  cloth  touched  with  equal  parts  of  sol.  fern  per- 
sulph.  and  carbolic  acid,  again  dried  thoroughly  by 
pressure  with  the  cloth,  and  then  painted  over  with  gutta- 
percha collodion.  If  this  be  thoroughly  done  absorption 
will  be  prevented  at  these  points  for  at  least  three  or 
four  days,  when  the  application  may  be  repeated. 

"  7.  After  the  labor,  when  the  patient  has  rested,  the 
vagina  should  be  syringed  out  with  an  antiseptic  solu- 
tion, and  a  suppository  of,  cocoa  butter,  containing  from 
three  to  five  grains  of  iodoform,  should  be  placed  within 
it  under  the  os  uteri.  A  syringe  with  intermittent  jets 
should  be  used,  which  will  wash  away  with  gentle  force 
all  blood-clots. 

"  8.  These  vaginal  injections  and  suppositories  should, 
in  cases  of  normal  labor,  be  repeated  every  eight  hours ; 
in  cases  of  difficult  or  instrumental  labor  twice  as  often, 
and  these  should  be  kept  up  for  at  least  ten  days,  the 
nurse  observing  to  the  last  the  precaution  already  men- 
tioned of  washing  her  hands  before  every  approach  to 
the  genital  tract  of  the  patient. 

"9.  When  catheterization  becomes  necessary,  it  is 
safest  to  employ  a  new  gum-elastic  catheter,  which  be- 
fore use  should  be  thoroughly  immersed  in  antiseptic 
fluid,  and  which  should  be  destroyed  at  the  conclusion  of 
the  case. 


October  4,  1884.] 


THE  MEDICAL  RECORD. 


373 


•'•'  10.  Last,  Dut  by  no  means  least,  let  the  physician  in- 
form himself  b>  personal  observation  as  to  the  competency 
of  the  nurse  to  syringe  out  the  vagina,  thoroughly  to  place 
the  antiseptic  suppositories  just  where  they  should  be, 
and  to  use  the  catheter  without  injury  to  the  patient." 

These  instructions  were  no  doubt  dictated  by  a  kind 
heart,  and  are  very  well  as  far  as  they  go ;  but  it  seems 
to  nie  that  in  view  of  the  prevalence  of  the  cause  of  sep- 
ticaemia, and  the  great  necessity  of  protecting  the  lives 
of  women,  if  it  is  only  for  the  purpose  of  child-bearing, 
they  fall  far  short  of  perfect  protection.  Perfect  protec- 
tion is,  humanly  speaking,  impossible,  I  presiune.  No 
matter  how  clean  the  doctor  and  nurse  may  be  when 
they  start  for  their  case,  who  knows  what  they  may  en- 
counter and  imbibe  on  the  way  ?  Sponging  a  bedstead 
and  mattress  is  scarcely  a  practical  suggestion  for  private 
practice,  especially  in  the  country.  It  appears  plain 
enough  that  in  this  country  especially,  where  there  is 
such  a  feverish  thirst  for  rapid  increase  of  population, 
and  in  fact  a  political  necessity  for  it,  that  the  Govern- 
ment roust  take  this  matter  in  hand.  The  country  should 
be  divided  into  districts,  and  in  each  district  should  be 
built  a  large  l3ring-in  hospital,  in  a  location  approved^  by 
the  Government  sanitary  engineer  or  commission.  The 
buildings  should  be  of  iron  and  glass,  with  glass  floors  ; 
the  bedsteads  of  iron,  japanned  ;  the  beds  of  rubber  and 
air;  carpets,  curtains,  and  upholstered  furniture  should 
have  no  abiding-place  in  the  buildings.  The  furniture 
of  the  lying-in  room  should  consist  of  a  bed  and  one  or 
two  white  glazed  earthenware  basins  only.  All  the  rooms, 
when  not  in  use,  should  be  kept  filled  with  the  vapor  of 
burning  sulphur.  There  should  be  a  sufficient  number 
of  suites  of  rooms,  numbering  from  i  to  i6  in  each  suite, 
so  that  the  patient  could  be  promoted  from  No.  i,  where 
she  was  delivered,  to  No.  i6,  advancing  a  room  daily, 
by  which  time  she  might,  under  ordinary  circumstances, 
be  considered  out  of  danger  of  septicaemia,  and  occupy 
the  nursery  parlors  until  she  was  fit  to  be  returned  to 
her  feraily  and  friends. 

Such  a  staff  of  doctors  and  nurses  should  be  kept 
constantly  ready  that  there  would  be  no  need  of  rushing 
from  one  case  to  another  without  sufficient  time  for  anti- 
septic ablutions  and  thorough  cleansing  and  rest.  Every 
pregnant  woman  in  the  district  should  be  compelled  by 
law  to  report  herself  at  the  hospital  at  least  two  weeks 
before  her  expected  confinement,  for  admission.  She 
should  be  immediately  scrubbed  with  some  antiseptic 
fluid,  and  thoroughly  new,  clean,  pure  clothing  provided 
for  her.  When  her  hour  came  she  should  be  again 
thoroughly  disinftcted  and  conducted  to  the  lying-in 
room  No.  i,  under  spray.  The  doctor  and  nurse  ap- 
pointed to  attend  her  should  be  thoroughly  washed — 
not  necessarily  together — disinfected,  and  having  been 
clothed  in  antiseptic  gauze — not  too  thin — placed  in  a 
disinfected  glass  case  and  rolled  into  the  room  No.  i, 
with  the  patient,  under  spray,  there  to  remain  till  the 
patient  is  delivered,  washed,  placed  in  a  glass  trough 
filled  with  warm  disinfecting  fluid,  and  passed  under  spray 
into  No.  2,  where  another  nurse  takes  charge  of  her  and 
places  her  comfortably  in  bed.  The  doctor  and  nurse 
now  retire  from  No.  i  as  they  entered,  under  spray,  to 
their  respecrive  bath-rooms,  and  after  being  thoroughly 
scrubbed  and  clothed  anew,  they  can  await  their  next 
patient.  In  the  meantime  everything  movable  is  taken 
out  of  No.  I,  and  the  room  thoroughly  disinfected  with 
burning  sulphur,  and  made  ready  for  patient  No.  2.  On 
the  following  morning  patient  No.  i,  now  in  room  No.  2, 
is  gently  and  kindly  washed,  placed  without  clothing  in 
the  trough  with  antiseptic  fluid,  and  rolled  under  spray 
into  room  No.  3,  and  put  into  a  warm,  clean  bed.  Room 
No,  2  is  now  cleaned,  disinfected,  and  made  ready  for 
patient  No.  2.  The  only  persons  having  access  to  these 
rooms  ordinarily  are  the  doctors  and  nurses,  and  they 
invariably  enter  and  retire  under  spray,  as  does  any  ad- 
ditional help  required  in  cases  of  emergency. 
All  the  details  of  nursing,  feeding,  and  medical  attend-  \ 


ance  are  to  be  carried  out  with  this  single  end  in  view, 
of  avoiding  the  possibility  of  septic-poisoning,  and  under 
the  strictest  scrutiny  of  the  Government  sanitary  engineer. 

These  details  would  be  quite  incomplete  without  tak- 
ing proper  precautions  against  the  possibility,  of  the 
mother  being  poisoned  through  fissures  in  her  nipples 
from  the  infants  mouth.  Millions  of  women  probably 
die  from  poison  absorbed  in  that  way.  Keep  the  child's 
mouth  faithfully  disinfected  ;  but  if  a  solution  of  bichlo- 
ride of  mercury  is  used  for  that  purpose,  it  will  be  prudent 
not  to  make  it  too  strong,  for  a  strong  solution  of  cor- 
rosive sublimate  might  prove  prejudicial  to  the  health  of 
any  but  the  very  strongest  of  infants. 

The  deaths  from  puerperal  fever  amount  to  about  one 
or  two  in  a  hundred  in  hospitals.  The  greatest  mortality 
is  in  hospitals.  In  private  practice,  especially  country 
practice,  the  mortality  is  less.  In  my  own  practice  of 
twenty-eight  years,  and  an  experience  of  about  a  thou- 
sand cases,  the  mortality  from  septicaemia  or  puerperal 
fever  has  not  been  greater  than  one  or  two  in  a  thousand, 
and  it  is  a  question  whether,  with  such  a  record  without 
any  antiseptic  precautions,  it  will  be  worth  while  to  build 
such  hospitals  as  I  propose  right  away,  or,  furthermore, 
whether  it  would  be  prudent  to  surround  the  parturient 
woman  with  such  meddlesome,  wearisome  watchfulness  as 
will  keep  her  constantly  on  the  ragged  edge  of  despair, 
and  most  certainly  produce  the  very  conditions  we  are 
most  anxious  to  avoid.  Death  from  puerperal  fever  is 
no  worse,  and  scarcely  more  certain,  than  death  from 
fear. 

Don't  allow  anything  I  have  written  to  lead  you  to 
suppose  that  I  have  anything  but  the  most  profound 
respect  for  science  ;  but  while  I  adore  the  teachings  of 
science,  I  object  to  exciting  unnecessary  fears  among  a 
class  of  patients  who  at  all  times  and  under  the  most 
favorable  circumstances  have  their  nervous  system 
severely  taxed.  More  than  half  the  lying-in  women  in 
Colchester  County  are  attended  by  mid  wives,  and  among 
them  puerperal  fever  is  more  rare  than  triplets.  Take 
courage,  therefore,  my  brothers,  especially  my  younger 
brothers,  and  fearlessly,  faithfully,  and  prayerfully  if  you 
like,  do  your  duty  to  your  puerperal  patients,  and  I 
doubt  not  that  He  who  hears  the  cry  of  the  young  ravens 
and  tempers  the  winds  to  the  shorn  lamb  will  throw  His 
strong  arm  and  His  disinfecting  breath  about  the  mothers 
of  the  future,  as  He  so  mercifully  and  consistently  has  in 
the  past. 

The  Right  of  Parents  to  Refuse  Surgical  Aid 
FOR  THEIR  Children. — In  a  communication  addressed 
to  the  RaccoglUore  Medico  Dr.  Turazza,  of  Venice,  raises 
the  question  as  to  how  far  parents  should  be  allowed  to 
interfere  with  the  medical  authorities  in  the  treatment  of 
their  children.  He  cites  some  instances  occurring  in  his 
hospital  practice  in  which  the  lives  of  children  were 
sacrificed  because  the  parents  would  not  consent  to  cer- 
tain necessary  surgical  operations.  And  he  asks  whether, 
in  the  case  of  a  sick  or  wounded  child  whose  only  hope 
of  recovery  rests  upon  the  performance  of  some  surgical 
measure,  the  parents  should  not  be  held  guilty  of  homi- 
cide when  they  obstinately  refuse  to  permit  of  the  opera^ 
tion.  And  he  also  asks  whether  the  surgeon,  in  such  a 
case  ought  not,  in  hospital  practice,  at  least  where  such 
a  thing  is  possible,  to  undertake  the  necessary  operation 
even  in  opposition  to  the  will  of  the  parents.  These  are 
certainly  important  questions,  but  at  the  same  time  ques- 
tions upon  which  there  is  room  for  wide  differences  of 
opinion.  Cases  of  this  sort  are  not  rare  in  which  a  life 
is  seemingly  sacrificed  to  the  ignorant  prejudices  ot 
parents,  who  cannot  perhaps  be  blamed  for  refusing  so 
sad  an  alternative.  And  yet  the  question  of  personal 
liberty  is  also  involved,  and  it  must  be  considered  how 
far  the  State  shall  be  allowed  to  encroach  upon  the 
family.  Dr.  Tarazzo  did  not  himself  attempt  to  answer 
the  points  raised  but  hoped  to  elicit  a  discussion  and* 
thereby  to  obtain  the  opinions  of  others. 


374 


THE  MEDICAL  RECORD. 


[October  4, 1884, 


^epavta  at  ^oapitala. 


NEW  YORK   EYE  AND   EAR  INFIRMARY. 
Aural  Service  of  SAMUEL  SEXTON,  M.D. 

(Reported  by  Wiluam  A.  Bartlbtt,  M.D.,  Assiitant  Surgeon* )1 
PAIN    IN   THE   EARS   DUE    TO     IRRITATION   IN    THE   JAWS. 

Some  of  the  following  cases  of  otalgia  and  inflammation 
of  the  ear  were  presented  by  Dr.  Sexton  to  the  physicians 
attending  the  aural  clinical  instruction  given  by  the 
School  of  Ophthalmology,  Otology,  and  Laryngology  of  the 
New  York  Eye  and  Ear  Infirmary ;  others  were  taken  from 
the  clinical  records.  The  experience  of  the  clinic  shows 
that  among  the  poor  earache  is,  in  many  instances,  due 
to  simple  otalgia  arising  from  dental  caries.  Sometimes 
it  is  found  that  even  when  otalgia  is  very  severe  indeed, 
no  signs  of  hyperasmia  or  of  inflammation  are  to  be 
found  in  any  part  of  the  ear.  Again>  in  certain  chronic 
or  acute  inflammatory  processes  present  in  the  ear,  very 
great  exasperation  of  the  case  is  manifestly  produced  by 
the  reflex  agencies  already  alluded  to. 

These  cases,  divested  of  other  details  than  those  more 
particularly  relating  to  the  subject,  are  taken  from  the 
record-book  in  the  order  in  which  they  presented  them- 
selves, and  may  be  said  to  be  fairly  illustrative  of  the 
troubles  under  consideration.  They  do  not,  however, 
represent  the  entire  number  of  cases  of  this  kind  seen 
during  the  period  of  time  embraced  between  the  first  and 
last  cases  noted.  Very  often,  it  may  be  premised,  a 
cure  is  effected  in  these  cases  by  the  extraction  of  dis- 
eased teeth. 

Case  1. — Bertha  S— ,  aged  six  (vol.  vii.,  p,  2). 
Otalgia, — Came  to  the  Infirmary  June  15, 1883.  For  the 
past  year  has  at  times  had  pains  in  ears,  and  two  years  ago 
one  of  them  discharged.  Several  days  ago  pain  began 
again  in  both  ears,  and  she  cannot  sleep  at  night  Ex- 
aminaiian  showed  the  left  canal  to  contain  a  mass  of 
cerumen;  the  right  membrana  tympani  lustreless  and 
hyperemic.  Tel^:  Lower  first  and  second  molars  on 
both  sides  mere  shells.  Treatment:  She  was  recom- 
mended to  have  the  shells  extracted  from  the  jaws,  and 
was  given  small  doses  of  the  tincture  of  aconite  root  for 
the  pains.  Remarks :  In  this  case  the  irritation  from  the 
carious  teeth  had  doubtlessly  been  the  cause  of  the  col- 
lection of  wax  ,in  the  left  canal  and  the  otalgia  in  the 
right  ear. 

Case  II. — Mary  B ,  aged  twenty-one  (vol.  vii.,  p. 

12).  Otalgia  ;  Cerumen. — Came  to  the  Infirmary  June 
22,  1883.  Complains  of  severe  pains  felt  in  left  ear 
for  two  weeks,  which  seem  to  constantly  get  worse. 
Worse  in  open  air,  and  at  night  so  intense  as  to  keep  her 
awake.  No  tinnitus  or  discharge.  Examination  :  Both 
canals  filled  with  cerumen.  Teeth :  Both  upper  wisdom- 
teeth  in  a  carious  state.  Both  lower  wisdom-teeth  just 
cut.  Owing  to  loss  of  some  of  the  upper  teeth,  a  vulcan- 
ite  plate  has  been  worn  for  four  years  past.  Remarks : 
The  irritation  caused  by  dental  caries  and  the  cutting  of 
the  lower  wisdom-teeth  in  the  above  case  was  increased, 
no  doubt,  by  the  vulcanite  plate  worn. 

Cask    III. — Nora    H ,  aged  forty   (vol.  vii.,  p. 

44).  Otitis  med.dif.  Externa  ;  Otalgia.^-^-Q.dxat  to  the 
Infirmary  August  7,  1883.  Has  had  headache  for  one 
year  and  a  half,  but  never  had  aural  trouble  before. 
Has^had  pains  in  the  right  ear  for  the  past  two  days  with- 
out discharge.  Examination  :  The  teeth  are  exceedingly 
bad,  and  the  right  external  auditory  canal  is  the  seat  of 
diffuse  inflammation.  Treatment :  Calc.  sulphide  in  one- 
half-grain  doses  every  three  or  four  hours;  tincture  of 
aconite  root  in  small  doses. 

August  loth. — Swelling  less  ;  feels  a  little  better.  The 
patient  probably  became  more  free  of  pain,  for  she  did 
uot  return. 


Case  IV. — Henrietta  G ,  aged   seven  (voL  vii^ 

p.  54).  Otalgia;  Odontalgia. — Came  to  the  Infirmary 
August  14,  1883,  with  her  own  diagnosis — that  her  ear- 
ache  was  due  to  toothache.  Examination :  The  right 
membrana  tympani  is  hyperaemic.  Teeth :  Both  of  the 
lower  six-year  molars  are  carious. 

Case   V. — N.   M ,  aged  ten   (vol.   vii,  p.   71). 

Otalgia. — Has  had  more  or  less  deafness  for  five  or  six 
years  past  and  teachers  have  occasionally  discovered  the 
defect  in  hearing.  Was  obliged  to  leave  school  on  ac- 
count of  otalgia.  Examination :  The  right  membrana 
tympani  lustreless,  with  prominent  folds  due  to  defective 
development.  The  left  canal  contains  considerable  soft 
wax,  obscuring  view  of  membcana  tympani.  Teeth:  All 
of  the  six-year  molars  are  carious  as  well  as  many  of  the 
other  teeth.  Hears  a  loud  voice  only  in  both  ears.  Treat- 
ment:  Small  doses  of  aconite  were  ordered  and  the 
teeth  were  to  be  attended  to. 

Case  VI. — ^Amelia  P ,  aged  twenty-two  (vol.  vii.,  p. 

84).  Otalgia, — Came  to  the  Infirmary  on  September  18, 
1883.  Heretofore  has  never  had  any  ear  trouble,  but  for 
past  two  weeks  has  had  a  pain  in  left  ear,  intermittent  in 
character,  and  worse  at  night  when  Ipng  down.  Had 
both  upper  canine  teeth  extracted  and  the  upper  right 
second  molar,  but  this  had  no  perceptible  influence  on  flie 
otalgia.  The  ear  pain  shoots  over  the  brow  and  down  the 
lower  jaw.  Has  some  laryngeal  discomfort  on  account  of 
pharyngitis  with  tendency  to  ozena.  Menstruation  if 
nornaal.  Examination  :  Right  canal '  small  and  mem- 
brana tympani  hyperasmic.  Canal  contains  small  quantity 
of  cerumen.  The  left  ear  in  same  condition  as  the  right 
Teeth:  Had  both  upper  second  bicuspids  removed  pre- 
vious to  coming.  In  the  lower  jaw  there  remain  in  a 
carious  state  the  two  right  inferior  bicuspids  and  the  first 
left  bicuspid.     Removal  of  the  dead  teeth  recommended 

Case  VII. — Lizzie  C ,  aged  twenty,  Irish,  seam- 
stress. Otalgia. — Came  to  the  clinic  October  1,  1883, 
giving  the  following  history :  No  specific,  malarial,  or 
rheumatic  taint.  Has  slight  pharyngitis  and  has  never 
suffered  from  dentalgia  to  any  great  extent.  During  the 
past  four  years  has  had  repeated  attacks  of  e»rache  on  left 
side  lasting  for  a  day  or  a  day  and  a  half,  unaccompanied 
by  tinnitus  or  deafness.  The  present  attack,  for  which 
she  came  for  relief,  began  four  weeks  ago  and  has  con- 
tinued constantly  and  quite  severe  to  date.  Examination : 
Teeth  covered  with  tartar,  several  being  carious  in  both 
the  upper  and  the  lower  jaw.  The  auditory  canals  and 
tympanic  membranes  normal  in  appearance.  Treat- 
ment: To  have  the  dead  teeth  extracted  and  tartar  re- 
moved. October  4th,  removal  was  followed  by  almost 
complete  relief.  October  7th,  has  been  entirely  free 
from  pains  since  last  note  was  made. 

Case  VIII. — Mary  L ,  aged  twenty-four  (vol  riL, 

p.  119).  Otalgia;  Otitis  externa  circ.  Acuta;  Disease  tf 
Teeth.^CsLme  to  the  Infirmary  October  30,  1883.  Takes 
cold  easily.  For  a  week  so  much  pain  in  right  ear  that 
rest  has  been  difficult,  and  in  consequence  she  is  very 
nervous.  The  right  ear  discharges  a  little  ;  tinnitus  is 
not  complained  of,  and  hearing  is  unaffected.  Two  years 
ago  the  ear  pained  without  discharging.  The  teeth  have 
ached  a  good  deal.  Examination  of  right  ear  showed 
that  the  meatus  was  closed  by  swollen  tissues;  hears 
a  low  voice  in  both  ears.  Teeth :  Upper  right  first  and 
second  molars  absent.  Lower  first  right  molar  carious, 
and  the  third  molar  just  cut.  Treatment:  Calc  suL, 
grs.  -^  every  two  hours  ;  hot  poultices. 

November  3d. — No  redness;  pains  ceased  on  ni^ht 
of  the  I  St  inst.,  when  a  discharge  began ;  canal  contains 
some  pus.  Treatment  continued.  Advised  to  have  dead 
teeth  removed  and  fillings  put  into  such  as  had  suffi- 
ciently healthy  pulps. 

It  is  noteworthy  in  the  above  case,  that  besides  dental 
caries  there  was  the  additional  irritation  caused  by  the 
rather  late,  and  probably  somewhat  difficult,  eruption  of 
a  wisdom-tooth  on  the  same  side  with  the  affected  ear, 
and  it  is  not  improbable  that  the  previous  otalgia  experi- 


October  4,  1884.] 


THE   MEDICAL   RECORD. 


375 


enced  was  dae  to  this  cause.  That  the  furuncle  was 
due  to  the  irritation  in  the  nerves  of  the  inferior  maxil- 
lary branch  seems  most  probable. 

In  commenting  on  this  subject,  Dr.  Sexton  drew  atten- 
tion to  the  frequent  attendance  of  females  suffering  from 
aural  trouble  through  sympathy  of  the  nerves,  and  the 
comparative  infrequency  of  the  complaint  among  men ; 
even  in  children,  he  thought  the  greater  number  of  otal- 
gias occurred  among  females.  In  reference  to  the  treat- 
ment of  these  cases,  it  was  believed  that  since  dentistry 
had  become  such  a  popular  business,  and  dead  and  dis- 
eased teeth  had  been  so  carefully  retained  in  the  jaws 
through  their  influence,  especially  among  the  better-to- 
do,  nervous  diseases  about  the  head  were  becoming 
alarmingly  common.'  The  very  general  custom  of  wear- 
ing false  teeth  in  the  mouth  attached  to  vulcanite  rubber, 
celluloid,  and  other  plates  was  also  an  evil  of  vast  pro- 
portions. Indeed,  he  sometimes  thought  that  the  evil 
done  through  ill-advised  dentistry  was  greater  than  the 
possible  good  arising  from  the  work  of  the  more  capable 
dentists. 

gt:00KjeBa  of  pCjedijcal  ^tietucje* 

The  Dangers  of  Removal  of  the  Thyroid  Gland. 
— Dr.  G.  Zesas  comes  to  the  conclusion,  based  upon  the 
results  of  a  number  of  experiments  on  animals,  that  the 
thyroid  gland  is  a  supplementary  organ  to  the  spleen, 
and  that  its  extirpation  is  followed  by  an  increase  in  the 
number  of  the  white  blood-corpuscles.  Death  invariably 
ensued  upon  the  removal  of  both  organs.  There  is  an- 
other much  more  important  function  of  the  thyroid  gland, 
however,  and  this  is  its  office  of  regulating  the  circula- 
tion within  the  cranium.  As  shown  by  Schiflf,  the  removal 
of  this  gland  is  followed  by  nervous  disturbances,  such  as 
stupor,  sluggish  movements  without  actual  paralysis, 
fibrillary  muscular  contractions,  and  tremor,  and  even  in 
some  cases  well-marked  tetanus.  Zesas  concludes  on 
this  account  that  removal  of  the  thyroid  gland  is  a  physio- 
logically unjustifiable  operation. —  Wiener  Medizinische 
Wochenschrift,  August  16,  1884. 

Masiced  SEPTiCiBMiA. — Dr.  E.  Moritz  relates  three 
cases  of  septicaemia  in  which  the  symptoms  were  of  an 
unusual  character,  leading  at  first  to  the  diagnosis  of  some 
other  condition.  In  the  first  case  the  patient  complained 
chiefly  of  headache  and  pains  in  the  limbs.  The  body 
was  covered  with  numerous  petechial  spots.  It  was 
supposed  at  first,  owing  to  the  peculiar  temperature 
curve,  that  the  case  was  one  of  relapsing  fever,  but  a 
daily  examination  of  the  blood  failed  to  show  the  pres- 
ence of  spirilli.  The  diagnosis  of  septicaemia  was  then 
made  and  this  was  confirmed  by  the  autopsy.  The  sec- 
ond case  was  supposed  to  be  one  of  diphtheria,  though 
the  probability  of  septicaemia  was  recognized  before 
death.  In  the  third  case  the  symptoms  seemed  to  point 
to  a  commencing  small-pox.  In  all  these  instances  the 
autopsy  f  revealed  small  sub-pleural  ecchymoses,  septic 
endocarditis,  a  large  softened  spleen,  and  parenchymatous 
degeneration  of  various  organs.  The  points  of  infection 
seemed  to  have  been  :  in  the  first  case  a  large  clavus  on 
the  sole  of  the  foot ;  in  the  second  a  diphtheritic  inflam- 
mation of  the  pharynx  ;  and  in  the  third  case  exten- 
sive submucous  extravasations  in  the  small  intestine.— 
Schmidfs  Jahrbucher^  July  23,  1884. 

Treatment  of  Strumous  Adenitis  by  Nitrate  of 
Silver. — Professor  Ferraris  recommends  daily  inunctions 
of  strumous  glands  with  an  ointment  containing  one 
drachm  of  nitrate  of  silver  to  ten  drachms  of  vaseline. 
Four  applications  usually  suffice  to  obtain  diminution  of 
pain,  or  even  complete  resolution  of  the  enlarged  glands. 
It  is  claimed  that  by  this  means  the  inflammation  is  lim- 
ited to  the  gland  tissue,  and  the  formation  of  fistulae  with 
subsequent  cicatrices  is  averted.^— ybi/rwa/  de  Midecine 
de  Paris  J  August  16,  1884. 


Hydatid  Cyst  of  the  Liver — Spontaneous  Cure. 
— Dr.  Conti  relates  the  case  of  a  man,  sixty  years  of  age, 
of  a  robust  physique,  who  had  always  enjoyed  excellent 
health  up  to  the  time  of  his  present  trouble.  He  began 
to  suffer  from  gastritis  with  violent  pains  over  the  hepat- 
ic region,  like  those  caused  by  the  passage  of  a  biliary 
calculus.  In  a  short  time  symptoms  of  hepatitis  ap- 
peared, fever,  jaundice,  and  enlargement  of  the  liver 
without  any  signs  of  a  distinct  tumor.  Finally  the  pa- 
tient fell  into  a  state  of  collapse,  with  constant  vomiting 
and  obstinate  constipation.  Some  days  later  he  had  a 
number  of  diarrhcetic  stools  mixed  with  pus.  On  exam- 
ination of  the  discharges  an  echinococcus  cyst  the  size 
of  an  orange  was  discovered.  The  vomiting  ceased, 
though  the  fever  and  diarrhoea  persisted  for  some  time, 
with  symptoms  of  pyaemic  infection.  Dr.  Conti  believes 
the  cyst  was  situated  on  the  under  surface  of  the  liver 
and  was  discharged  by  ulceration  through  the  wall  of 
the  coXon,— Journal  de  Midecine  de  Paris y  August  16, 
1884. 

ExsEci'iON  OF  the  Fascia  in  Dupuytren^s  Contrac- 
tion.— In  an  article  in  the  Wiener  Medizinische  Wochen- 
schrift  of  August  9,  1884,  Dr.  R.  Gersuny  describes  a 
new  operative  measure  used  by  him  in  the  treatment  of 
contraction  of  the  palmar  fascia.  He  makes  a  longi- 
tudinal incision  of  the  integument  over  the  prominent 
aponeurotic  bands,  and  then,  through  the  opening  caused 
by  the  retraction  of  the  skin,  excises  this  part  of  the 
palmar  fascia.  The  wound  is  then  easily  closed  by  a  few 
sutures  and  dressed  antiseptically.  The  advantages  of 
this  method,  he  claims,  are  that  there  are  no  thickened 
and  knotty  cords  left  in  the  aponeurosis,  and  further,  that 
owing  to  the  direction  of  the  line  of  incision  in  the  skin 
there  is  but  little  retraction  of  the  tissues  and  the  wound 
heals  readily. 

Urinary  Disturbances  in  Diseases  of  the  Nervous 
System. — ^The  urinary  organs  are  often  the  seat  of  vari- 
ous troubles  during  the  course  of  nervous  diseases.  In 
an  article  on  this  subject  {Revue  Mddicale^  August  23, 
1884)  Dr.  Charles  F6r6  groups  these  phenomena  under 
disturbances  of  secretion,  excretion,  and  sensibility.  A 
diminution  in  the  quantity  of  urine,  he  says,  is  observed, 
especially  in  severe  forms  of  hysteria,  when  the  ischuria 
may  persist  for  several  days.  In  such  cases  the  vomited 
matters  contain  urea,  a  point  of  some  value  in  the  de- 
tection of  malingerers.  Under  the  influence  of  strong 
emotions  there  may  be  a  decrease  in  the  amount  of  urine 
passed,  as  well  as  a  relatively  smaller  proportion  of  urea 
and  chlorides.  Polyuria  may  be  caused  by  undue  sexual 
excitement,  severe  neural^a,  and  especially  the  milder 
forms  of  hysteria.  Polyuna  may  also  follow  the  renal  or 
vesical  crises  of  locomotor  ataxia,  and  may  exist  as  a 
permanent  condition  in  aflections  of  the  mesocephalon. 
Albuminuria  and  glycosuria  may  accompany  this  con- 
dition, not  only  following  lesions  in  the  floor  of  tlie 
fourth  ventricle  but  also  occurring  in  diseases  of  the 
mesocephalon.  A  slight  degree  of  albuminuria  is  met 
with  also  in  several  convulsive  neuroses,  and  more  par- 
ticularly in  epilepsy.  The  author  explains  this  occurrence 
by  supposing  submucous  extravasations  into  the  walls  of 
the  bladder,  similar  to  the  facial  ecchymoses  sometimes 
occasioned  by  an  epileptic  attack.  If  the  urine  contains 
a  large  quantity  of  albumen,  it  is  merely  coincidental  and 
due  to  some  other  pathological  condition.  A  transitory 
neuropathic  glycosuria  may  follow  physical  or  mental 
fatigue,  sexual  excesses,  or  depressing  emotions.  The 
increase  of  urea  and  the  urates  may  be  encountered  in 
any  of  the  aflections  with  clonic  or  tonic  convulsions. 
Retention  may  be  due  to  spasm  of  the  sphincter  or  pa- 
ralyses of  the  walls  of  the  bladder.  Paralytic  retention 
is  common  in  apoplectic  coma,  traumatic  aflections  of 
the  cord.  Pott's  disease,  acute  or  subacute  myelitis.  In 
certain  cases  of  this  kind  the  urine  becomes  rapidly  alka- 
line, a  fact  explainable  only  on  the  theory  of  some 
'  trophic   trouble.  _^  True    incontinence    occurs  only  in 


376 


THE  MEDICAL  RECORD. 


[October  4,  1884, 


acute  myelitis  or  in  traumatic  aflfections  of  the  cord. 
Unconscious  micturition  is  common  in  tabes  dorsalis, 
general  paralysis  of  the  insane,  and  cerebral  tumors  lo- 
cated in  the  mesocephalon.  The  neurotic  incontinence 
of  childhood  is  often,  the  author  asserts,  a  forerunner  of 
epilepsy  or  ataxia.  The  various  forms  of  irritable  blad- 
der may  be  met  with  in  acute  or  chronic  nervous  con- 
ditions, in  neurasthenia,  spinal  meningitis,  or  locomotor 
ataxia.  The  author  does  not  agreie  with  M.  Geffier,  who 
asserts  that  ataxia  may  be  recognized  by  its  urinary 
symptoms  apart  from  any  pthers,  but  he  thinks  that  these 
troubles  may  often  be  of  purely  nervous  origin,  and  are 
most  probably  of  this  nature  in  the  absence  of  any  well- 
defined  lesions  of  the  urinary  tract. 

Scrofula  and  Tuberculosis. — The  history  of  the 
teachings  upon  tuberculosis  and  scrofula  is  a  somewhat 
curious  one.  In  the  sixteenth  century  scrofula  was  the 
only  condition  recognized,  but  little  by  little  tuberculosis 
began  to  assume  an  independent  position  in  the  minds 
of  pathologists,  and  up  to  within  a  comparatively  recent 
time  they  were  supposed  to  be  two  separate  and  distinct 
diatheses  or  morbid  conditions.  But  now  tuberculosis 
began  to  get  the  upper  hand,  and  one  after  another  of 
the  so-called  scrofulous  affections  were  recognized  to  be 
tubercular  in  character.  Koch's  discovery  of  the  tubercle 
bacillus  has  lent  additional  weight  to  these  views,  and  at 
the  present  day  there  are  very  few  writers  who  would 
deny  the  tubercular  nature  of  fungus  arthritis,  lupus, 
caseous  cervical  adenitis,  and  cold  abscess.  While  some 
deny  the  very  existence  of  scrofula  as  opposed  to  tuber- 
culosis, others  retain  the  name,  using  it  merely  to  desig- 
nate a  diathesis  or  morbid  predisposition.  The  exterior 
manifestations  of  this  condition  have  been  reduced  to 
certain  forms  of  eczema,  impetigo,  sluggish  inflamma- 
tion of  the  mucous  membranes,  and  possbily  superficial 
adenitis.  But  it  is  not  certain  that  even  these  local 
manifestations  of  the  scrofulous  diathesis  may  not  event- 
ually be  found  to  be  caused  by  a  mild  form  of  tuber- 
culosis. Dr.  J.  Grancher  has  recently  inoculated  guinea- 
pigs  with  pus  and  crusts  of  impetigo,  and  publishes  the 
results  obtained  by  him  in  L  Union  Medicate  of  August 
21,  1884.  The  experiments  were  all  conducted  with 
great  care,  every  precaution  being  taken  to  protect  the 
animals  from  contagion  from  without.  Several  inocula- 
tions were  first  made  with  pus  taken  from  suppurating 
glands  of  the  neck  and  from  spina  ventosa  of  the  thumb, 
and  in  every  instance  the  animals  acquired  tuberculosis. 
In  the  second  series  the  pus  was  taJcen  from  impetigo 
crusts,  strumous  conjunctivitis,  etc.  The  results  were 
negative  in  all  but  two  out  of  twenty  three  cases.  In 
the  two  successful  inoculations  ^the  pus  was  not  taken 
from  the  impetigo  crusts,  but  in  one  case  from  a  neigh- 
boring papule,  and  in  the  other  from  a  small  abscess  of 
the  skin.  Dr.  Grancher  concludes  that  his  experiments, 
as  far  as  they  go,  would  seem  to  show  that  the  superficial 
scrofulous  inflammations  are  not  in  themselves  tuber- 
culous, but  that  they  may  be  the  door  through  which 
the  specinc  microbe  gains  admittance  into  the  human 
organism. 

Treatment  of  Suppurating  Buboes. — This  affection 
may  be  cured,  according  to  Delahousse,  in  from  six  to 
twelvedaysbyadopting  the  following  procedure  i^V  Union 
MedicaUy  August  5,  1884):  The  skin  is  washed  with  soap 
and  warm  water,  shaved,  and  then  washed  again  with  a 
one  per  cent,  solution  of  carbolic  acid.  These  precautions 
having  been  taken,  the  abscess  is  punctured  and  a  solu- 
tion of  chloride  of  zinc  (one  part  to  six  of  distilled  water) 
is  injected  into  the  cavity.  After  being  retained  for  a 
short  time  in  contact  with  the  walls  of  the  abscess,  it  is 
let  out  and  replaced  by  a  full  injection  of  carbolized 
water.  The  wound  is  then  covered  with  eight  or  ten 
folds  of  gauze  saturated  with  carbolized  water  and  gly- 
cerine (four  per  cent.).  The  dressing  is  retained  for 
forty-eight  hours,  when  the  former  procedure  is  repeated, 
the  same  precautions  being  observed. 


Treatment  of  Dandruff. — M.  Vidal  uses  the  fol- 
lowing pomade  in  the  treatment  of  dry  seborrhcea  of 
the  scalp  {Revue  Midicale^  August  23,  1884) '  Pre- 
cipitated sulphur,  one-half  ounce  ;  balsam  of  Peru,  one- 
half  drachm;  cocoa  butter,  three  drachms;  castor-oil, 
one  and  one-half  ounce.  The  proportions  of  the  cocoa 
butter  and  castor-oil  should  be  varied  according  to  the 
season  to  obtain  a  pomade  of  the  desired  consistency. 

Acute  Nicotinism. — In  experiments  upon  dogs  and 
rabbits  Dr.Tomassio  found  that  a  subcutaneous  injection 
of  pure  nicotine  caused  a  reduction  of  temperature  of 
from  1.5°  to  2°.  Immediately  following  the  injection 
there  was  a  slight  muscular  trembling,  and  a  diminution 
in  the  number  and  force  of  the  pulsations  and  respiratory 
movements.  Collapse  followed  in  from  forty  to  fifty 
minutes.  At  the  autopsy  the  author  found  congestion 
and  hemorrhage  into  the  lungs,  the  brain,  and  the  ab- 
dominal organs.  There  was  an  intense  odor  of  tobacco 
in  all  the  tissues. — Lyon  Medical^  August  24,  1884. 

Traumatism  and  Tuberculosis. — At  a  recent  meet- 
ing of  the  Surgical  Society  of  Paris  (Z*  Union  Medicale^ 
August  5, 1884),  M.  Kirmisson  related  the  case  of  a  child, 
five  and  one-half  years  old,  suffering  from  hemiplegia  with 
contractures,  coming  on  a  week  after  a  fall  on  the  head. 
The  appearance  of  the  cerebral  symptoms,  severe  pain 
in  the  temple  on  the  side  of  the  injury,  the  plaintive  cries, 
vomiting,  etc.,  led  to  the  supposition  of  a  purulent  collect 
tion  following  probably  a  fracture  of  the  cranium.  Yet  the 
slow  progress  of  the  symptoms,  following  at  some  interval 
the  traumatism,  caused  M.  Kirmisson  to  think  that  there 
might  be  a  mere  coincidence  between  the  injury  and  the 
appearance  of  a  tuberculous  or  cancerous  neoplasm.  The 
skull  was  nevertheless  trephined,  but  with  negative  re- 
sults, and  the  child  died  within  twenty-four  hours.  At 
the  autopsy  the  bones,  membranes,  and  surface  of  the 
brain  were  found  to  be  healthy.  But  in  the  centre  of  the 
right  hemisphere  there  was  a  tuberculous  mass  which  had 
destroyed  the  optic  thalamus  and  corpus  striatum.  Histo- 
logical  examination  established  the  tuberculous  nature 
of  the  tumor.  The  speaker  related  several  other  cases, 
collected  from  the  literature,  showing  a  simple  coincidence 
between  traumatism  and  the  development  of  tuberculosis. 

Gastric  Secretion  in  the  Fcetus. — When  iodide  of 
potassium  is  given  to  pregnant  rabbits  it  quickly  appears 
in  the  amniotic  fluid.  It  is  often  found  also  in  the 
stomach  of  the  fcetus,  but  this  was  supposed  to  be  due  to 
swallowing  of  the  fluid,  and,  indeed,  the  fact  was  cited 
by  Zuntz  as  a  proof  that  the  foetus  possessed  the  power 
of  deglutition.  Krukenberg,  however,  has  found  this 
substance  in  the  stomach  of  the  fcetus  of  the  guinearpig, 
after  its  subcutaneous  injection  into  the  mother,  before 
it  was  present  in  the  amniotic  fluid.  This  would  show 
that  the  iodide  of  potassium  passed  through  the  placenta 
into  the  foetal  circulation  and  was  thence  excreted  (?)  into 
the  stomach. —  Wiener  Medizinische  Wochenschrtft^  Au- 
gust 23,  1884. 

Iodoform  in  the  Treatment  of  Gonorrhceal  Oph- 
thalmia.— Dr.  L.  Guaita  has  treated  successfully  a  se- 
vere case  of  blennorrhagic  conjunctivitis  on  the  follow- 
ing plan  :  Every  morning,  after  having  thoroughly  bathed 
the  eye  with  a  solution  of  boracic  acid,  he  filled  the  con- 
junctival cul-de-sacs  with  a  quantity  of  finely  pulverized 
iodoform.  In  addition,  the  eye  was  covered  with  iodo- 
form gauze  and  a  layer  of  gutta-percha  cloth.  This 
operation  causes  only  a  slight  smarting,  which  disappears 
in  a  few  minutes.  If  the  iodoform  gives  rise  to  any  severe 
pain  it  is  because  it  is  not  finely  enough  pulverized.— 
Journal  de  Medecine  de  Paris^  August  23,  1884. 

Pelvic  HiEMATOCELE. — In  a  thesis  on  this  subject  Dr. 
Jousset  has  collected  the  statistics  of  upward  of  thirty 
cases  of  pelvic  haematocele,  more  than  twenty  of  which 
ended  fatally  and  were  examined  post-mortem.  As  a 
result  of  his  studies  Hi  arrived  at  the  following  con- 
elusions  :  i.  This  affection  is  not  a  disease  sui  generis^ 


October  4,  1884.] 


THE  MEDICAL  RECORD. 


377 


but  is  a  symptom  of  several  very  different  conditions.  2. 
The  tumor  itself  is  so  characteristic  that  the  diagnosis 
may  be  made  without  an  exploratory  puncture,  provided 
only  that  the  patient  be  seen  early.  3.  The  symptoms 
of  haematocele  are  for  the  most  part  those  of  the  disease 
which  has  occasioned  the  extravasation.  4.  One  variety 
of  haematocele  arises  in  consequence  of  extra-uterine 
pregnancy  or  from  rupture  of  the  non-gravid  condition. 
In  this  case  the  affection  occurs  suddenly  with  signs  of 
internal  hemorrhage,  either  after  some  vague  symptoms 
of  pregnancy  or  in  the  midst  of  perfect  health.  This 
manner  of  onset  is  rare  and  is  of  ominous  significance.  5. 
Another  form  of  haematocele,  also  rare  and  of  evil  prog- 
nosis, occurs  in  connection  with  uterine  hemorrhage.  It 
comes  on  rapidly  after  metrorrhagia,  or  more  slowly  after 
dysmenorrhoea.  6.  The  most  common  variety  is  that 
which  arises  in  the  course  of  pelvic  peritonitis  from  rup- 
ture of  the  vessels  in  the  pseudo-membrane.  The  prog- 
nosis in  this  form  is  of  less  gravity.  7.  Surgical  measures 
arc  only  permissible  when  rupture  into  the  abdominal 
cavity  is  threatened. — Centralblatt  fUr  Gyndkologie,  Au- 
gust 23,  1884. 

Hygiene  of  the  Mouth  in  the  Nbw-Born. — In  an 
article  on  the  diseases  of  the  mouth  in  infants  (erythema, 
Bednar's  aphthse,  stomatitis  catarrhalis,  thrush,  etc.).  Dr. 
Epstein  states  it  as  his  belief  that  the  most  frequent  cause 
of  these  affections  is  to  be  found  in  the  manner  of  wash- 
ing the  mouth  of  the  new-bom  child.  The  cleansing  of 
the  mouth,  as  usually  performed  by  nurses  and  midwives, 
is  done  roughly  and  unskilfully,  and  not  only  causes  in- 
jury to  the  mucous  membrane,  but  is  also  frequently  the 
means  of  introducing  infection  from  without.  He  advises 
that  the  buccal  cavity  be  washed  only  once  a  day  after 
the  morning  bath,  and  protests  especially  against  cleans- 
ing the  mouth  immediately  after  birth  without  previous 
disinfection  of  the  nurse's  hands.  In  the  treatment  of 
aphthae  no  attempt  should  be  made  to  remove  any  patches 
except  those  that  lie  within  sight  and  easy  reach,  and 
any  undue  force  should  be  most  carefully  avoided. — 
CeniralbkUt  fur  GyndkologUj  August  23,  1884. 

Symmetrical  Brachydactylus. — Dr.  K.  L&bker  re- 
lates the  case  of  an  otherwise  normally  developed  wo- 
man who  had  a  congenital  shortening  of  four  fingers 
due  to  absence  of  the  middle  phalanx.  The  thumb  was, 
however,  normal.  The  author  argues  that,  in  this  case 
of  symmetrical  absence  of  the  middle  phalanx  of  all  four 
fingers,  if  the  first  phalanx  of  the  thumb  were  really  the 
middle  phalanx,  it  would  also  have  been  wanting.  Hence 
the  metacarpus  poUicis  cannot  be  regarded  as  a  phalanx. 
—Centralblatt  fur  Chirurgie^  August  23,  1884. 

The  Weight  of  Drops. — M.  Bo^mond  has  ascertained 
by  a  number  of  trials  that  the  weight  of  a  drop  depends 
upon  the  external  diameter  of  the  tube,  and  not,  as  is 
usually  supposed,  upon  its  internal  diameter.  The  size 
of  the  latter  affects  only  the  rapidity  of  the  flow.  The 
nature  of  the  liquid  (water,  alcohol,  ether,  etc.)  also  de- 
termines the  weight  of  the  drop  independently  of  any 
substances  which  it  may  hold  in  solution.  In  order  to 
obtain  drops  of  distilled  water  (of  a  temperature  of 
58.5®  F.)  weighing  five  centigrammes — or  80  drops  to  a 
drachm — the  external  diameter  of  the  tube  should  be 
exactly  -A-  inch.  The  author  gives  a  table  showing  the 
comparative  weights  of  drops  of  different  medicinal  prep- 
arations falling  from  a  tube  of  the  given  size.  One 
gramme  (15  minims)  of  distilled  water  is  equivalent  to  20 
^ops ;  of  alcohol  at  90**,  61  drops  ;  at  60®,  52  drops ;  of 
an  essential  oil,  48  drops  ;  of  a  volatile  oil,  50  drops ;  of 
laudanum,  from  33  to  35  drops,  varying  according  to  its 
strength.  The  tinctures  give  a  varying  number  of  drops 
according  to  the  proportion  of  alcohol.  An  aqueous 
solution,  no  matter  what  its  strength,  gives  the  same 
number  of  drops  as  distilled  water.  Thus  two  solutions 
of  muriate  of  morphia  of  ^  and  -^^  respectively  give 
each  20  drops  to  the  gramme. — Journal  di  MMfcine  de 
Paris,  August  23,  1884, 


Periproctitis  Simulating  Typhoid  Fever. — Profes- 
sor Llicke  relates  the  case  of  a  strong  and  healthy  man  who 
was  struck  on  the  abdomen  with  a  pole,  but  without  receiv- 
ing any  apparent  injury.  Two  weeks  later  he  was  seized 
with  typhoid  symptoms,  high  fever,  and  diarrhoea.  These 
were  followed  by  tenesmus,  bloody,  and  then  purulent 
discharges,  a  gangrenous  piece  of  the  rectum  was  passed, 
and  soon  the  man  died.  At  the  autopsy  there  was  found 
a  perforation  in  the  posterior  wall  of  the  rectum  and  a 
large  fecal  abscess  extending  to  the  sacrum.  There 
were  no  typhoid  lesions  in  the  intestinal  canal,  no  caries 
of  the  sacrum  or  coccyx,  and  no  actinomycosis.  The 
author  believed  that  the  affection  was  caused  by  a  lodg- 
ment of  the  actinomycosis  fungus  in  the  folds  of  the 
rectum,  giving  rise  to  ulceration  and  abscess.  The  original 
fungus  of  actinomycosis  can  often  not  be  found  in  abscesses 
of  which  it  is  the  cause. — Deutsche  Medicinal-Zeitung, 
August  21,  1884. 

An  Instrument  for  Pencilling  Children's 
Throats. — Dr.  H.  Guttmann  has  devised  an  instrument 
to  facilitate  the  making  of  local  applications  to  the 
throat  in  dealing  with  refractory  children.  It  consists 
simply  of  a  wedge  of  hard  rubber,  with  rounded  edges, 
to  the  broad  end  of  which  is  attached  a  handle.  The 
wedge  is  perforated  to  permit  the  passage  of  the  brush.  By 
the  use  of  this  instrument  it  is  claimed  that  the  possibility 
of  injury  to  the  soft  parts  is  done  away  with,  the  diph- 
theritic throat  may  be  pencilled  with  great  ease,  and  lastly 
the  danger  of  infection  from  coughed-up  matters  is 
avoided. — Deutsche  Medicinal-Zeitungy  August  18, 1884 

Acute  Painful  Paraplegia. — Dr.  Dumolard  de- 
scribes under  this  name  a  special  form  of  paraplegia,  not 
mentioned  in  the  books,  of  which  he  has  had  occasion 
recently  to  observe  several  instances.  The  affection 
commences  with  lumbar  pain  and  a  sensation  of  uneasi- 
ness and  stiffness  in  the  back.  This  pain,  variable  in  its 
intensity  and  duration,  begins  in  the  lumbar  region  and 
extends  up  the  back,  passing  sometimes  into  the  neck. 
There  may  also  be  pains  in  the  thighs  and  legs,  not  fol- 
lowing, however,  the  course  of  the  sciatic  nerve  nor  local- 
ized in  the  joints,  but  extending  over  the  entire  surface 
of  the  limbs.  When  the  patient  attempts  to  walk,  his 
gait  is  like  that  of  a  person  suffering  from  rheumatism. 
In  severe  cases  the  pains  begin  with  great  intensity  and 
are  accompanied  with  a  slight  febrile  movement.  After 
some  days  of  suffering  the  patient  finds  himself  paralyzed 
in  his  lower  limbs  and  is  uuable  to  rise  from  the  bed. 
The  reflexes  are  so  exaggerated  that  the  least  touch  on 
the  feet  excites  tetanic  contractions.  The  general  con- 
dition of  the  patient  is  never  serious,  the  pulse  does  not 
exceed  80,  and  the  skin  is  moist.  The  bladder  is  usually 
somewhat  weakened,  but  neither  the  paralysis  of  the 
bladder  nor  of  the  limbs  is  ever  total  The  pains  are 
usually  confined  to  the  region  of  the  kidneys  and  to 
the  lower  limbs  during  the  whole  course  of  the  affection, 
but  sometimes  they  leave  these  parts  suddenly  and  attack 
the  arms,  which  then  also  become  paretic.  The  acute 
stage  of  the  disease  usually  lasts  from  ten  to  fifteen  days, 
the  pain  then  rapidly  subsides,  and  the  paresis  of  the 
bladder  and  extremities  begins  to  disappear.  In  all  the 
cases  observed  by  Dr.  Dumolard  complete  recovery  took 
place  after  from  thirty  to  forty  days.  The  cause  of  this 
affection  is  not  determined,  though  cold  and  damp  seem 
to  have  some  share  in  its  production.  The  persons  at- 
tacked had  arrived  at  the  middle  age.  Counter-irritation 
along  the  vertebral  column,  purgatives,  bromide  of  po- 
tassium, chloral,  and  morphine  are  the  measures  which 
seemed  to  do  the  most  good  in  Dr.  Dumolard' s  hands. 
The  author  does  not  regard  the  disease  as  belonging  to 
any  form  of  meningitis,  but  thinks  it  may  be  identical 
with  an  epidemic  affection  recently  observed  in  Spain. 
This  was  characterized  by  pain  and  weakness  in  the  lower 
extremities,  and  having  once  appeared  in  the  village  of 
Azannon  recurred  nearly  every  year  under  an  epidemic 
form. — LAheille  M^dicale^  August  25,  t884. 


378 


THE  MEDICAL  RECORD.r. 


[October  4,  1884. 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &.  Co.,  Nos.  56  and  58  Ufayette  Place. 

New  Yorky  October  4,  1884. 

THE  ALCOHOL  QUESTION. 

When  that  goody  young  man  Telemachus  and  his 
celestial  guide  Mentor,  both  models  of  excellent  pro- 
priety for  the  times  in  which  they  lived,  were  on  their 
memorable  travels,  they  became  acquainted  with  a  race 
of  people  who  probably  had  been  educated  from  science 
text-books  similar  to  those  which  are  largely  in  use  at 
the  present  day.  "  Do  they  drink  wine  ?"  Telemachus 
asks  of  Adoam.  "  Oh,  no  ! ''  replies  Adoam  ;  "  they  would 
never  <io  that !  It  is  not  because  they  want  grapes — no 
country  grows  such  delicious  ones ;  but  they  content 
themselves  with  eating  them  before  they  are  spoiled  by 
fermentation,  and  they  fear  wine  as  the  comiptor  of  man. 
It  is  a  species  of  poison,  they  say,  which  maddens  peo- 
ple ;  it  does  not  kill  a  man  outright,  but  it  renders  him  a 
brute.  Men  can  preserve  their  health  and  strength  with- 
out wine  ;  with  wine  they  run  the  risk  of  ruining  their 
health  and  losing  their  good  manners."  ' 

In  discussing  the  alcohol  question  from  a  medical 
standpoint  we  have  no  occasion  for  den3nng  that  the 
ideal  society  which  Fdn^lon  describes  was  right  in  its 
judgment  and  in  its  practice,  and  that  the  Utopia  of  our 
civilization  will  be  distinguished  by  temperance  and 
sobriety.  It  is,  however,  notoriously  a  fact  that  society 
is  not  now,  and  will  not  for  many  years  to  come  be,  in 
that  ideal  condition;  that  debilitating  diseases  abound 
from  whose  results  the  remedial  use  of  alcohol  often 
offers  the  best  means  of  defence ;  that  multitudes  of  per- 
sons have  weakly  neurasthenic  constitutions  which  seem 
to  be  benefited  by  the  vinous  stimulus  indulged  in 
moderation ;  that,  in  fact,  alcoholic  medication  con- 
stitutes an  important  part  of  the  physician's  armamen- 
tarium :  all  this  must  be  conceded,  besides  the  uses  of 
alcohol  in  the  arts. 

The  two  aspects  of  the  subject  must  be  kept  in  mind 
in  any  attempt  to  treat  it  fairly ;  the  dark  side  with  its 
horrors,  which  are  undisputed  (representing  the  abuses)  \ 
the  counterpart,  or  the  strictly  medical  side,  with  which 
chiefly  physicians  are  concerned  and  which  has  to  do 
with  the  benefits  obtainable  from  a  physiological  and 
therapeutical  use  of  alcohol,  which  is  properly  a  medica- 
ment, and  as  such  of  so  great  value  that  Raymond  Lully 
styles  it  "the  supreme  cordial  of  the  human  body."' 
The   discussion  of  the  question  is  further  complicated 

>  F6i61on*i  T^l^maque,  Lhr.  viii. 

>  StiU^  :  Therapeutics  and  Materia  Medica ;  artide.  Alcohol. 


by  the  fact  that  the  effects  of  alcoholic  stimulants  vary 
according  to  the  quality  of  the  spirit  used  and  the  quantity 
taken,  and  according  as  the  individual  is  sick  or  well. 

1.  With  regard  to  quality,  this  would  have  to  be  con- 
sidered under  several  heads,  such  as  the  kind  of  alcoholic 
liquor  used,  whether  fermented  or  distilled,  and  from  what 
source,  and  whether  modified  by  age  and  by  the  natural 
or  artificial  mixture  of  other  substances,  such,  especially, 
as  the  higher  atomic  (amyl,  butyl,  propyl)  alcohols.  It 
is  known  that  age  has  an  improving  effect  on  both  fer- 
mented and  distilled  liquors,  by  some  process  as  yet  un- 
known. Eliminating  such  noxious  impurities  as  fusel 
oil  and  aldehyde,  in  any  case,  whether  used  as  a  bever- 
age or  as  medicine,  the  action  of  the  intoxicant  would  be 
different  on  the  economy  according  as  the  product  in- 
gested were  fresh  from  the  fermenting  vat  or  still,  or  had 
become  mellow  from  age. 

That  the  natural  or  artificial  contaminations  of  spiritu- 
ous liquors,  of  which  the  most  common  and  the  most 
baneful  is  undoubtedly  amyl  alcohol,  or  fusel  oil,  mate* 
rially  modify  the  stimulant  or  narcotic  effect  of  the 
alcoholic  preparation  is  well  known  to  physiologists  at 
the  present  day.  Of  this  we  have  lately  had  a  decisive 
demonstration  in  the  instructive  experiments  performed 
on  animals  (dogs  and  swine)  by  Drs.  Dujardin-Beau- 
metz  and  Audig^,  of  Paris.*  These  experiments  proved 
the  exceeding  noxiousness  of  all  the  higher  atomic 
alcohols  as  compared  with  ethyl  alcohol,  as  also  the 
powerfully  toxic  nature  of  the  alcoholic  derivatives,  acetic 
aldehyde,  acetic  ether,  and  acetone.  This  was  shown 
by  the  results  of  acute  poisoning  with  all  these  substances 
in  the  state  of  purity,  and  the  state  of  dilution,  and  by 
the  results  of  chronic  poisoning  which  demonstrate  the 
relative  innocuousness  of  rectified  wine,  grain,  beet,  or 
potato  spirits  as  contrasted  with  crude  spirits  that  have 
not  undergone  rectification.  A  wide  experience,  more- 
over, has  proved  that  the  least  noxious  of  the  intoxicating 
beverages  are  those  which  approach  the  nearest  to  the 
ntatured  products  of  vinous  fermentation. 

Organic  chemistry  has  taught  us  that  the  alcohol  which 
distinguishes  vinous  fermentation  and  vinous  distillation 
is  the  ethylic — C,H,0.  It  has  been  again  and  again 
made  clear  that  while  a  certain  moderate  quantity  of 
diluted  ethyl  spirits  may  be  borne  by  the  human  organ- 
ism not  only  with  impunity,  but  often  with  the  happiest 
physiological  results,  the  ingestion  of  even  inconsiderable 
quantities  of  the  other  alcohols — unfortunately  too  gen- 
erally  components  in  notable  proportion  of  the  crude 
liquors  of  commerce — is  attended  with  results  which  are 
always  pathological  and  which  are  often  most  deplorable. 

2.  Under  the  head  quantity  we  should  have  to  consider 
acute  and  chronic  poisoning  by,  and  the  stimulant  and 
narcotic  action  of  the  alcohols.  Here  there  is  no  dearth 
of  facts  from  which  to  form  judgments,  and  we  now  knovr 
the  fixed  toxic  dose  for  every  member  of  the  alcohol 
series.  It  has  been,  for  instance,  shown  that  the  medium 
quantity  of  ethyl  alcohol  sure  to  cause  death  within 
twenty-four  hours  is  eight  grammes  per  kilogramme  of 
weight  of  the  person  or  animal  ingesting  the  spirit,  and  that 
the  quantity  of  the  other  alcohols  is  much  less ;  it  has 
also  been  shown  that  when  the  daily  dose  of  pure  ethyl 

1  See  iheie  experiments  detailed  at  length  in  the  Therapeutic  Gaiette  for  July 
and  August,  1884,  with  comments  by  Dr.  Hurd,  of  Newburyport,  Mas«. 


October  4,  1884.] 


THE   MEDICAL  RECORD. 


379 


spirits  does  not  exceed  one  gramme  for  each  kilogramme 
of  weight,  it  may  be  borne  without  inconvenience  for  a 
rery  long  time,  no  perceptible  lesions  on  the  part  of  the 
digestive,  hepatic,  or  nervous  systems  being  produced.' 

3.  With  regard  to  the  action  of  alcohol  on  the  human 
system,  every  physician  is  well  aware  of  the  difference  of 
effect,  whether  the  individual  be  in  robust  health  or 
whether  he  be  suffering  from  the  debility  of  disease,  quan- 
tities being  toxic  in  the  one  case  which  are  therapeutical 
and  restorative  in  the  other.  There  is  no  doubt  that  in 
sickness  we  often  obtain  a  healthful  stimulant  action  from 
doses  which  to  a  well  man  would  be  narcotic  and  detri- 
mental ;  nor  should  there  be  any  confusion  between  these 
terms  stimulant  and  narcotic.  The  author  of  the  best  work 
in  the  English^  if  not  in  any  language  on  stimulants  and 
narcotics  (Anstie),  defines  a  stimulant  as  "  any  substance 
which,  brought  to  bear  in  proper  quantities  upon  the 
nervous  system,  facilitates  nutrition."  At  the  head  of 
all  stimulants  he  would  place  oxygen.  Anstie's  investi- 
gations show  that  alcohol  is  a  food,  medicine,  or  poison, 
according  to  the  circumstances  under  which  it  is  taken 
and  according  to  the  quantity  taken.  The  effect  of  a  small 
quantity  he  calls  true  stimulation,  and  urges  that  this  is 
often  beneficial,  and  comparable  to  the  effect  of  food ;  a 
large  dose  produces  narcotism,  and  is  always  injurious. 
A  small  stimulant  dose  is  physiological,  a  large  narcotic 
dose  is  pathological,  and  between  the  two  there  is  a 
definite  poison  line,  varying  with  each  individual  case. 
He  denies  that  true  stimulation  is  ever  followed  by  re- 
active depression.  True  stimulation,  whether  produced 
by  the  oxygen  we  breathe  or  by  the  wine  we  drink,  facili- 
tates nutrition  and  hence  supports  life.    Such,  in  brief,  is 

j    Anstie's  doctrine. 

A  careful  consideration  of  the  alcohol  question  firom 

'  this  standpoint  and  in  the  manner  we  have  above  indi- 
cated (which  is  the  only  fair  way)  shows  how  difficult 
and  how  complex  is  the  problem  with  which  legislators, 

I  sociologists^  and  educators  are  dealing  ;  moreover,  it  will 
be  seen  how  great  are  the  difficulties  in  the  way  of  a  proper 
and  comprehensive  presentation  of  the  subject  in  text- 
books on  physiology  designed  to  instruct  youthful  minds 
in  the  truths  concerning  the  actions  of  alcohol  on  the 

'  human  system.  Better  that  the  children  attending  our 
public  schools  should  grow  up  without  this  technical 
knowledge,    but    with    the    examples    duly    impressed 

,  upon  them  of  the  evils  of  intemperance  on  individuals, 
their  families,  'and  on  society,  all  of  which  come  under 
their  daily  observation  and  may  be  made  by  parent  or 
teacher  the  theme  of  many  an  effective  moral  lesson, 
than  that  such  loose'and  superficial  teachings  and  half- 
tmths  as  characterize  the  treatment  of  the  subject  by 
some  of  our  physiological  books  should  be  instilled  into 
their  minds,  much  of  it  to  be  unlearned  in  after  years. 


DEAD  TEETH  IN  THE  JAWS. 

The  columns  of  The  Record  some  months  since  con- 
tained several  interesting  communications  to  the  effect 
that  the  retention  of  these  defective  members  was  not 
always  unattended  with  danger  to  the  patient.  The 
'*  clinical  notes  on  aural  disease  "  in  another  part  of  The 
RicoRD  furnish  additional  evidence  of  the  perils  of  tooth- 

^  See  die  Recherdies  sur  la  pultaaiice  toxiques  des  Alcools,  by  Dujardin- 


saving.  It  is  stated  by  the  careful  observer  that  not  only 
a  large  number  of  aural  diseases,  including  otalgia  pure 
and  simple,  may  arise  from  the  irritation  of  diseased 
teeth,  but  that  doubtlessly  a  great  deal  of  the  nervous- 
ness with  which  some  people  are  affected  at  the  present 
day  is  attributable  to  the  ill-advised  retention  of  dead 
teeth  and  the  unskilfol  stopping  of  teeth  where  the  pulp 
is  sensitive,  though  not  as  yet  irreparably  impaired  by 
caries.  It  would  seem,  from  the  accumulated  evidence 
on  this  point,  that  perhaps  the  time  is  nigh  at  hand 
when  medical  men  should  be  themselves  better  informed 
concerning  diseases  of  the  jaws  and  mouth,  rather  than 
refer  the  ailments  of  this  region  to  individuals  whose 
limited  knowledge  of  medicine  does  not  prevent  them 
from  "  treating  "  dead  teeth  long  after  their  presence  in 
the  jaws  has  given  rise  to  alveolar  abscesses  and  neuralgias 
more  or  less  painful. 

One  recalls  in  this  connection  the  rather  amusing  emular 
tion  shown  by  the  numerous  correspondents  of  a  London 
medical  journal  some  years  ago  concerning  the  possibility 
of  replacing  teeth  that  had  recently  been  lost,  as  though 
such  a  proceeding  were  one  to  be  commended.  It 
would  not  be  strange  if,  in  the  course  of  events,  the 
day  would  soon  come  when  just  the  contrary  practice 
would  prevail — when  all  teeth  without  pulps,  and  hence 
in  process  of  more  or  less  rapid  decay,  as  well  as  those 
which  the  deposit  of  tartar,  or  other  cause,  had  entirely 
divested  of  periosteal  nourishment,  would  be  promptly 
condemned  as  unfit  to  remain  in  the  jaws — ^regarded,  in 
fact,  as  foreign  bodies  liable  to  give  rise  not  only  to  cere- 
bral irritation  and  disease  in  the  organs  of  special  sense, 
through  the  propagation  of  local  disturbances  in  the 
mouth  to  the  regions  mentioned,  but  to  endanger  like- 
wise the  general  health  through  purulent  matter  discharged 
into  the  mouth  from  alveolar  abscesses,  to  be  continuously 
swallowed  for  a  long  time,  or,  indeed,  in  some  instances, 
to  be  absorbed  and  thus  produce  septicaemic  poisoning. 

It  is  certainly  gratifying  to  note  the  establishment  of 
instruction  in  oral  surgery  in  some  of  the  medical  schools, 
and  it  is  to  be  hoped  that  this  subject  will  receive  the  at- 
tention its  importance  demands.  It  must  not  be  sup- 
posed, however,  that  ''  dentistry "  should  be  taught,  for 
surely  this  in  its  broadest  sense  by  no  means  constitutes 
oral  surgery  ;  nor  does  the  latter  embrace  the  former. 
The  stopping  of  teeth  and  the  fitting  of  plates  m  the 
mouth,  requiring  skill  and  experience  for  their  successful 
performance,  need  no  more  be  taught  the  medical  student 
than  the  manufacture  of  surgical  instruments  and  ap- 
pliances. On  the  other  hand,  there  has  always  been  a 
desire  to  combine  the  medical  art  with  the  mechanics  of 
dentistry,  but  the  medical  training  usually  given  the 
dental  apprentice  is  entirely  too  superficial  to  qualify 
him  to  treat  disease, -whether  arising  from  the  state  of  the 
teeth  or  not ;  in  point  of  fact,  his  training  does  not  al- 
ways prevent  harm  being  done  to  persons  who  are  will- 
ing to  have  placed  in  the  mouth  some  one  or  more  of  the 
numerous  harmful  dental  appliances  of  the  present  day. 


SOME  THERAPEUTICAL  DELUSIONS. 
We  have  received  from  an  esteemed  correspondent  an 
extremely  pungent  criticism  of  the  therapeutical  fashions 
of  the  day.     The  writer  eamesdy  urges  the  necessity  of 
a  more  critical  and  careful  analysis  of  therapeutical  ex- 


38o 


THE  MEDICAL  RECORD. 


[October  4,  1884. 


perience,  and  prays  for  a  cyclone  to  strike  some  three- 
fourths  of  the  therapeutical  recommendations  now  in 
vogue.  He  concludes  by  enumerating  a  series  of  thera- 
peutical delusions  which  he  finds  to  be  more  or  less  cuirent. 

While  we  greatly  deprecate  nihilism  in  therapeutics,  be- 
lieving that  that  phase  of  medical  feeling  has  had  its  day, 
we  earnestly  desire  to  encourage  a  more  critical  study  of 
the  action  of  remedies  and  of  alleged  therapeutic  results. 

We  have  carefully  examined  the  **  delusions  "  set  forth 
by  our  correspondent,  and  find  that  in  the  main  they 
agree  with  results  of  the  more  conservative  clinicians  and 
of  pharmacological  experiment. 

They  are  as  follows  : 

"  It  is  a  delusion  that  veratrum  viride  or  aconite  will 
abort  croupous  pneumonia  or  essentially  modify  its  course ; 
that  potas.  chlorate  is  of  any  use  in  catarrhal  angina ; 
that  potassium  nitrate  is  an  antipyretic,  anti-rheumatic, 
or  (to  any  appreciable  extent)  diuretic ;  that  lime-water 
will,  in  practice,  dissolve  a  diphtheritic  or  croupous  mem- 
brane ;  that  nitrate  of  silver  is  of  any  value  in  epilepsy  ; 
that  the  excessive  and  continued  use  of  iron  induces 
plethora  with  dizziness,  flushings,  and  palpitations ;  that 
iron  should  be  given  in  phthisis ;  that  mercury  is  anti- 
plastic  and  antiphlogistic  ;  that  arsenic  has  any  value  in 
diabetes  mellitus ;  that  potassium  iodide  promotes  ab- 
sorption of  serous  exudations  and  non-specific  connec- 
tive tissue  in  hyperplasias ;  that  sulphur  and  sulphur  in 
baths  is  of  any  value  in  rheumatism ;  that  charcoal,  when 
moist  in  the  stomach  and  intestines,  has  any  absorptive 
power,  or  is  of  any  use  in  flatulence  by  virtue  of  that 
power;  that  dilute  acids  are  < cooling,' 1.^.,  lower  tem- 
perature and  lessen  heart- action  in  the  non-febrile  ;  that 
colchicum  is  of  benefit  in  rheumatism ;  that  drinking 
sulphuric  acid  prevents  chronic  lead-poisoning;  that 
iodoform  given  internally  is  anything  but  a  poor  substi- 
tute for  potassium  iodide ;  that  croton-chloral  has  a 
specific  efiect  on  the  fifth  cranial  nerve ;  that  tannic 
acid  (or  the  plants  containing  it)  is  of  any  value  given 
internally  for  hemorrhages,  except  perhaps  those  of  the 
stomach  and  bowels,  or  that  it  is  of  any  value  as  a 
gargle  in  chronic  pharyngitis,  or  that  it  is  an  astringent 
to  mucous  surfaces  and  blood-vessels  ;  that  turpentine  is 
a  stimulant  to  the  heart  and  nervous  system  ;  that  musk 
is  a  nerve  or  heart  stimulant  (it  belongs,  with  turpen- 
tine, to  nerve  depressants)  ;  that  ox-gall  is  of  the  slightest 
therapeutical  utility  at  either  end  of  the  digestive  tract ; 
that  hydrocyanic  acid  in  ordinary  medicinal  doses  is 
either  a  local  or  general  sedative  (it  is  rather  an  irri- 
tant) ;  that  quinine  in  either  small  or  large  doses  is  a 
stomachic  tonic,  except  in  convalescence  from  malarial 
attacks  ;  that  hydriodic  acid  has  any  specific  effects  other 
than  those  possessed  by  the  iodides." 


PALATO-GRAPHY. 
Dr.  Harrison  Allen,  of  Philadelphia,  has  described  * 
a  method  of  recording  the  movements  of  the  soft  palate, 
which  is  likely  to  prove  of  much  scientific  and  perhaps 
practical  importance.     He  says  : 

"  When  a  straight  rod  is  passed  through  the  nose  from 
before  backward  in  the  living  subject,  as  far  as  is  possi- 


ble, it  will  be  found  to  impinge  against  the  roof  of  the 
naso-pharynx.  In  this  position  the  rod  is  not  influenced 
by  any  motions  of  the  soft  palate ;  but  if  the  end  of  the 
rod  which  remains  without  the  nostril  be  raised  so  that 
the  rod  be  brought  in  contact  with  the  anterior  border  of 
the  nostril,  the  pharyngeal  end  of  the  rod  will  lie  in  a 
position  which  will  cause  a  decided  motion  to  be  trans- 
mitted to  it  when  the  soft  palate  is  raised" 

By  the  use  of  a  flexible  copper  wire  attached  to  the 
rod,  and  then  to  a  head-band,  the  rod  is  kept  in  place  on 
the  palate,  and  the  free  end  is  allowed  to  rest  upon  a  re- 
volving drum  or  kymographion,  where  it  registers  its 
movements.  It  is  then  found  that  the  rod  produces  dif- 
ferent curves  with  every  motion  of  the  palate  in  speak- 
ing, coughing,  hawking,  breathing,  etc. 

Dr.  Allen  has  studied  these  curves  and  found  them  to 
vary  for  each  of  the  dififerent  vowels  and  consonants,  as 
well  as  for  different  words. 

The  tracings  obtained  are  tolerably  alike  for  the  same 
words,  although  dififerent  individuals  sometimes  produce 
different  tracings. 

Dr.  Allen  gives  illustrations  of  the  tracings  obtained 
with  vowels,  consonants,  syllables,  words,  phrases,  etc. 

He  believes  that  palato-graphy  may  be  of  use  in  study- 
ing the  mechanism  of  the  soft  palate  in  disease,  as  well 
as  in  health.  It  may  probably  prove  of  use  in  studying 
stammering,  and  in  determining  the  degree  of  degenera- 
tion of  the  levator-palati  muscles  in  progressive  dry 
aural  catarrh. 

It  may  also  be  employed  in  studying  phonetics,  and 
the  suggestion  is  made  that  the  instrument  may  be  avail- 
able for  the  comparative  study  of  language,  for  the  in- 
struction of  the  deaf,  and  for  the  formation  of  a  new 
system  of  short-hand  writing. 

While  one  can  see  many  practical  objections  to  such 
a  rose-colored  view  of  the  future  of  the  palate-myograph, 
it  is  evident  that  Dr.  Allen  has  made  an  addition  to  our 
instruments  of  precision  which  will  be  of  considerable 
value. 


Icvaa  of  tlije  WHtiik. 


r.  1 A  New  Method  of  Recording'^the  (Motions  of  the  SoftJPalatcT  By^Harriion 
Allen,  M.D.  ^PhiUddphia  :iP.tBlakistonJ&»Son.Mx884.  j 


The  Dosage  of  Phosphorus. — Dr.  Rutgers,  of  Rot- 
terdam, directs  attention  to  a  typographical  error  occnr- 
ring  in  The  Record  of  April  5, 1884,  p.  376.  It  is  there 
stated  that  Dr.  Kassowitz  recommends  teaspoonful  doses 
of  a  solution  of  phosphorus  in  cod-liver  oil,  x  part  to 
1,000,  in  the  treatment  of  rickets.  The  proportion  should 
have  been  given  as  i  to  10,000,  the  former  dose  being 
that  suitable  for  an  adult,  and  of  course  much  too  large  for 
a  young  child.  We  always  endeavor  to  be  scrupulously 
exact  in  transcribing  directions  for  the  treatment  of  dis- 
ease, especially  when  the  question  of  the  dosage  of  power- 
ful drugs  is  involved,  but  errors  will  occasionally  creep 
in,  despite  the  greatest  vigilance.  It  is  always  a  good 
plan  before  accepting  any  formula,  no  matter  by  whom 
recommended  nor  where  found,  to  make  a  simple  calcu- 
lation in  order  to  determine  the  exact  amount  of  the 
active  ingredient  contained  in  the  prescribed  dose.  If 
this  be  done  in  every  instance,  errors  of  transcription  or 
of  printing  can  readily  be  detected,  and  the  possibly  un- 
oward  consequences  averted. 


October  4.  1884.] 


THE  MEDICAL  RECORD. 


381 


HOMffiOPATHY  AND  THE    GaRFIELD  MEMORIAL  HOSPI- 

^^_In  order  to  satisfy  the  demands  of  certain  homoeo- 
paths at  Washington,  the  Trustees  of  the  Garfield  Me- 
morial Hospital  have  adopted  the  following  by-law : 
"The  executive  committee  shall  provide  that  homoeo- 
pathic treatment  shall  be  furnished  to  those  patients  who 
desire  iU  provided  the  physician  selected  for  such  purpose 
shall  render  his  services  upon  the  same  terms  as  the 
medical  staff  of  the  hospital." 

Death  of  a  Noted  Epidemiologist. — The  death  is 
announced  of  Mr.  John  N.  Radcliflfe,  M.R.C.S.,  one  of 
the  best  of  modem  epidemiologists.  He  was  the  author 
of  a  number  of  painstaking  reports  upon  epidemics, 
being  especially  skilful  as  a  historian  in  that  line.  He 
vas  for  some  years  one  of  the  two  public  health  inspec- 
tors of  London. 

The  Cholera. — Up  to  September  30th,  the  total  num- 
ber of  deaths  from  cholera  in  Europe  was  not  far  from 
15,000.  Of  these  Italy  has  over  8,000  ;  France,  about 
6^000 ;  Spain,  400. 

In  France  there  are  now  23  Departments  where  cases 
have  been  reported,  and  19  that  have  had  deaths.  The 
stricken  communities  number  237.  Marseilles  has  had 
1,733  deaths  ;  Toulon,  982  ;  Aries,  383 ;  Perpignan, 
186 ;  Aix,  162  ;  and  Carcassonne,  106.  The  disease 
has  nearly  disappeared  from  France  and  Spain,  and  it 
continues  to  abate  in  Italy. 

The  total  number  of  fresh  cases  in  Italy,  September 
29tb,  was  355,  with  212  deaths.  This  includes  171 
cases  and  100  deaths  at  Naples. 

A  cablegram  from  Paris,  September  30th,  states : 
"The  cholera  commission  appointed  to  investigate  the 
epidemic  here  have  submitted  their  report.  They  state 
that  they  followed  the  progress  of  the  disease  by  hourly 
examining  the  blood  of  persons  stricken  with  it.  They 
found  that  in  each  case  at  first  a  few  of  the  globules  pre- 
sented an  unhealthy  appearance,  then  one-third  were 
affected,  then  one-half,  then  two-thirds,  and  finally  death 
resulted.  The  important  fact  was  developed  that  all  the 
globules  were  not  simultaneously  affected." 

The  American  Academy  of  Medicine. — The  Ninth 
Annual  Meeting  of  the  Academy  will  be  held  at  the  Johns 
Hopkins  University,  Baltimore,  Md.,  on  Tuesday  and 
Wednesday,  October  28th  and  29th,  beginning  on  Tues- 
day, at  three  o'clock  p.m.     The  address  of  the  President, 
Dr.  Benjamin  Lee,  of  Philadelphia,  will  be  delivered  at 
eight  o'clock  p.m.     Papers  will  be  read  by  Dr.  N.  Allen, 
of  Lowell,   Mass.,  on  "Physiology  in  its  more  Public 
Relations  (public  health,  physical  culture,  family  institu- 
tions, true  civilization)";  Dr.  H.  O.  Marcy,  of  Boston, 
Mass.,  on  **The  R61e  of  Bacteria  in  Infectious  Diseases"; 
Dr.  R.  Stansbury  Sutton,  of  Pittsburg,  on  "The  Teach- 
ings  Derived  from  Observations  in  One  Hundred  and 
Thirty-seven  Abdominal  Sections";  Dr.  H.  Knapp,  of 
New  York,    on   "Statistics  of  Glaucoma'';   Dr.  A.  L. 
Gihon,  U.  S.  Navy,  on  "The  Trade  Aspect  of  Medicine"; 
Dr.  E.  Jackson,  of  Philadelphia,  on  "The  Examination 
of  Applicants  for  Licence  to  Practice,  a  Means  of  Rais- 
ing the    Standard  of  Medical  Education";    Dr.  A.  C. 
Kemper,   of  Cincinnati,  O.,  on  "Medical  Fees";  Dr. 
V.  P.  Gibney,  of  New  York,  on  "Some  Comparative 
Results  of  Treatment  of  Chronic  Articular  Osteitis  of 


the  Hip";  Dr.  C.  C.  Bombaugh,  of  Baltimore,  Md.,  on 
"  The  Place  of  the  Physician  in  Literature  ";  Dr.  Peter 
D.  Keyser,  of  Philadelphia,  on  "The  Relation  of  the 
Medical  Colleges  to  Preliminary  Education";  Dr.  A.  D. 
Rockwell,  of  New  York,  on  "The  Induction  Coil,  its 
Varieties  and  the  Diflferential  Indications  for  their  Use"; 
Drs.  Dunglison  and  Marcy,  '*  Report  on  Laws  Regulating 
the  Practice  of  Medicine  in  the  United  States  and  Canada." 

The  Comma-Bacillus  found  in  the  Mouth  and 
Fauces  of  Healthy  Persons. — Dr.  T.  R.  Lewis,  of 
the  British  Army,  has  been  studying  the  microscopical 
appearances  in  cholera  at  Marseilles.  He  states  that  he 
finds  the  comma^bacillus  in  all  cases,  but  that  he  has 
also  found  this  bacillus  in  the  mouth  and  fauces  of 
healthy  individuals.  Although  Dr.  Lewis  regards  this 
fact  as  one  of  great  significance,  it  cannot  be  so  re- 
garded as  yet,  since  he  did  not  test  the  oral  micro- 
organisms by  cultivation. 

Collective  Investigation  in  Connecticut. — We 
have  received  a  circular  from  the  "  Committee  on  Matters 
of  Professional  Interest  in  the  State,"  in  which  is  pre- 
sented a  plan  for  collective  investigation  among  the  mem- 
bers of  the  State  Society.  The  subjects  chosen  for  in- 
vestigation are :  convallaria  maialis,  piscidia  erythrina, 
cascara  sagrada,  and  the  oleates.  A  list  of  questions 
under  each  head  is  furnished,  and  the  members  are  each 
urged  to  do  whatever  is  possible  to  promote  the  success 
of  the  investigation. 

Dr.  Alexander  H.  Stephens  and  Sir  James  Paget. 
— In  an  address  delivered  before  the  New  York  State 
Medical  Society  at  Albany,  in  1850,  we  believe,  Dr.  Al- 
exander H.  Stephens,  President,  gave  a  very  similar  series 
of  facts  and  line  of  reasoning  regarding  the  cost  of  sick- 
ness and  disease  that  Sir  James  Paget  did  in  his  much- 
quoted  address  at  the  Healtheries.  Dr.  Stephens'  ad- 
dress was  not  "  much-quoted  "  however.  Times  were 
not  then  ripe. 

The  New  York  Post-Graduate  Medical  School 
AND  Hospital  opened  its  Session  of  1884-85  on  Octo- 
ber I  St,  in  its  new  and  spacious  building,  where,  during 
the  summer,  many  changes  have  been  made  to  add  to 
the  comfort  of  the  physicians  who  attend  the  clinics.  The 
building  is  four  stories  high,  has  a  frontage  of  ninety  ' 
feet,  and  has  a  large  yard,  in  which  is  the  well-ventilated 
building  for  the  teaching  of  operative  surgery,  regional 
anatomy,  and  the  like.     In  the  basement  is  found  the 
pharmacy  and  patients'  waiting-room  ;  on  the  first  floor 
the  amphitheatre,  comfortable  and  light,  for  surgical,  gy- 
necological, ophthahnic,  and  other  operations,  and  for 
the  various  clinics ;  also  a  second  lecture-room  for  ortho- 
pedic surgery,  and  instruction  in  naval,  military,  and 
State  hygiene ;  together  with  eight  other  rooms  for  the 
treatment  of  patients,  and  the  reading-room,  well  sup- 
plied  with  medical  journals.     On  the  second  floor  is  the 
large  room  for  laryngoscopy,  ophthalmoscopy,  and  oto- 
scopy, with  facilities  for  teaching  thirty  at  once,  if  neces- 
sary.    The  new  histological  and  pathological  laboratory 
is  also  most  thoroughly  equipped,  and  contains  one  of 
the  largest  collections  of  specimens  in  this  country.     A 
photographic  gallery  for  taking  pictures  of  important 
cases  is  a  new  feature.    The  two  upper  floors  are  devoted 
to  hospital  purposes,  where  private  patientsjjare  treated. 


382 


THE   MEDICAL  RECORD. 


[October  4,  1884. 


either  in  separate  rooms  or  in  a  general  ward,  recently 
opened.  Some  of  the  private  rooms  are  marvels  of 
beauty.  During  the  last  session  one  hundred  and  eigh- 
teen physicians  studied  at  the  School,  and  the  present 
demand  for  post-graduate  instruction  is  on  the  increase. 
During  the  winter  clinics  will  be  given  on  the  following 
topics  :  Surgery,  Clinical  and  Operative  ;  Gynecology  ; 
Venereal  Diseases ;  Diseases  of  the  Eye  and  Ear ;  Phy- 
sical Diagnosis ;  General  Medicine ;  Diseases  of  Chil- 
dren ;  Urinary  Analysis  ;  Surgical  Dressings ;  Obstet- 
rics ;  Applied  Anatomy  ;  Diseases  of  the  Nervous  Sys- 
tem ;  Orthopedic  Surgery ;  Diseases  of  the  Nose  and 
Throat ;  Skin  Diseases ;  Pathology  and  Histology ; 
Hygiene  ;  Pharmacy  ;  Anatomy  and  Physiology  of  the 
Nervous  System  ;  and  Genito-urinary  Diseases. 


^vmvi  and  Hatr^  ^exus. 


Official  List  cf  Changes  in  the  Staiums  and  Duties  of  Officers 
serving  in  the  Medical  Department,  United  States  Army, 
from  September  21  to  September  27,  1884. 

MiDDLETON,  Passmore,  Major  and  Surgeon.  Having 
reported  from  sick  leave  of  absence,  assigned  to  duty  at 
Fort  Leavenworth,  Kan.  S.  O.  188,  par.  2,  Headquar- 
ters Department  of  Missouri,  September  19,  1884. 

White,  R.  H.,  Captain  and  Assistant  Surgeon.  As- 
signed to  duty  as  Post  Surgeon  at  Fort  Winfield  Scott, 
Cal.,  relieving  Assistant  Surgeon  A.  S.  Polhemus,  who, 
upon  being  relieved  will  report  to  commanding  officer 
Alcatraz  Island,  Cal.,  for  duty.  S.  O.  113,  par.  i. 
Headquarters  Department  of  California,  September  19, 
1884. 

Hall,  John  D.,  Captain  and  Assistant  Surgeon.  As- 
signed to  duty  at  Fort  Townsend,  Wash.  Ten,  to  relieve 
Surgeon  R.  S.  Vickery.  Surgeon  Vickery  on  being  re- 
lieved directed  to  report  to  commanding  officer  Van- 
couver Barracks,  Wash.  Ten,  for  duty.  S.  O.  140,  par. 
3,  Headquarters  Department  of  Colorado,  September  15, 
1884. 

Tesson,  L.  S.,  Captain  and  Assistant  Surgeon.  Di- 
rected to  report  to  commanding  officer  Fort  Stockton, 
Texas,  for  temporary  duty.  S.  O.  127,  par.  3,  Head- 
quarters Department  of  Texas,  September  22,  1884. 

Birmingham,  H.  P.,  First  Lieutenant  and  Assistant 
Surgeon.  Leave  of  absence  extended  twenty  days.  S. 
O.  116,  par.  2,  Headquarters  Division  of  the  Missouri, 
September  22,  1884. 

Maddox,  T.  J.  C,  First  Lieutenant  and  Assistant 
Surgeon.  Directed  to  report  to  commanding  officer  post 
of  San  Antonio,  Texas,  for  duty.  S.  O.  127,  par.  5, 
Headquarters  Department  of  Texas,  September  22,  1884. 

Barrows,  C.  C,  First  Lieutenant  and  Assistant  Sur- 
geon. Leave  of  absence  extended  one  month.  S.  O. 
97,  par.  6,  Headquarters  Division  of  the  Pacific,  Septem- 
ber 19,  1884. 

DiETZ,  W.  D. ,  First  I^ieutenant  and  Assistant  Surgeon. 
Assigned  to  duty  at  Fort  Selden,  N.  M.  (Post  Surgeon), 
S.  O.  187,  par.  4,  Headquarters  Department  of  Missouri, 
September  18,  1884. 

McCaw,  W.  D.,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  as  Post  Surgeon,  Fort  Craig, 
N.  M.  S.  O.  187,  par.  5,  Headquarters  Department  of 
Missouri,  September  18,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U,  5. 
Navy,  during  the  week  ending  September  27,  1884. 

Bloodgood,  D.,  Medical  Inspector.  To  Washington 
for  examination  preliminary  to  promotion,  and  as  to 
qualifications  for  sea  duty,  October  i,  1884. 


HoRD,  W.  T.,  Medical  Director.  As  member  of  Naval 
Examining  Board,  October  i,  1884. 

Turner,  T.  J.,  Medical  Director.  As  member  of 
Naval  Examining  Board,  October  i,  1884. 

Boyd,  J.  C,  Passed  Assistant  Surgeon.  Placed  on 
waiting  orders,  September  25,  1884. 

Oberly,  a.  S.,  Surgeon.  To  Washington  for  exam- 
ination  preliminary  to  promotion,  and  as  to  qualifications 
for  sea  duty,  October  i,  1884. 


§ljepr0rtB  at  ^atxzlizs. 


AMERICAN  GYNECOLOGICAL  SOCIETY. 

Ninth  Annual  Meeting,  held  in  Chicago,  September  30, 
October  i  and  2,  1884. 

(By  Telegnph  to  Thb  Mbdicax.  Rbcokd.) 

Tuesday,    September    30TH — First    Day — Morning 
Session. 

The  Society  was  called  to  order  by  the  President,  Dr. 
Albert  H.  Smith,  of  Philadelphia. 

Dr.  W.  H.  Byford,  of  Chicago,  gave  the  address  of  wel- 
come. 

Dr.  John  C.  Reeve,  of  Dayton,  O.,  read  a  paper  on 

INVERSION   OF  THE    UTERUS. 

The  following  points  were  among  those  upon  which 
opinions  were  divided  : 

First. — Could  inversion  of  the  uterus  occur  entirely 
independent  of  pregnancy  or  polypus,  or  even  in  a  nul- 
liparous  organ  ?  There  was  a  fair  argument  in  favor  of 
the  proposition  that  it  might  so  occur,  and  some  cases 
seemed  to  prove  it. 

Second. — Did  inversion  of  the  uterus  always  begin  at 
the  fundus  uteri  ?  There  seemed  sufficient  data  to  es- 
tablish the  proposition  that  inversion  could  begin  at  the 
cervix. 

Third. — Did  puerperal  inversion  of  the  uterus  ever 
occur  except  at  or  immediately  after  delivery  ?  Testi- 
mony rendered  argument  in  its  support  unnecessary ; 
several  cases  were  mentioned  which  sustained  the  propo- 
sition. 

Fourth. — Might  inversions  of  the  uterus  take  place 
•  without  sufficient  symptoms  to  attract  attention  or  to  in- 
dicate that  anything  had  gone  wrong  ?  Cases  were  cited 
which  sustained  the  affirmative  of  the  proposition. 

The  paper  was  discussed  by  Drs,  John  Scott,  of  San 
Francisco  ;  W.  H.  Byford,  of  Chicago  ;  B.  B.  Browne,  of 
Baltimore  ;  A.  Dunlap,  of  Sprinfigeld,  O. ;  E.  W.  Sawyer, 
of  Chicago ;  and  W.  T.  Howard,  of  Baltimore. 

Dr.  H.  p.  C.  Wilson,  of  Baltimore,  read  a  paper  on 

FOREIGN   BODIES    IN   THE   ABDOMEN   AFTER  LAPAROTOMY. 

He  had  been  unsuccessful  in  gathering  statistics  but  had 
succeeded  in  collecting  twenty-one  cases.  Of  these  only 
five  had  been  published.  Six  occurred  in  this  country, 
fifteen  in  Europe.  In  six  American  cases  sponges  were 
left  in  five,  and  forceps  in  the  remaining  one.  Dr.  Wil- 
son gave  a  history  of  his  case,  that  of  a  woman  five 
months  in  pregnancy,  upon  whom  he  performed  ovari- 
otomy. Abortion  occurred  eighteen  days  after  the  opera- 
tion. A  sponge  remained  in  the  abdominal  cavity  five 
months  ;  it  was  then  discharged  piecemeal  through  the 
abdominal  walls,  and  the  patient  recovered  completely. 

The  paper  was  discussed  by  Dr.  Thoacas,  of  New 
York.  He  said  he  was  in  the  habit  of  attaching  long 
pieces  of  tape  to  each  sponge  to  prevent  its  loss  in  the 
abdomen.  He  had  never  had  an  accident  occur  to  him- 
self except  once  in  four  or  five  hundred  laparotomies, 
and  then  a  piece  of  sponge  was  found  post-mortem,  only 
a  few  hours  after  operation. 

Dr.  a.  Reeves  Jackson,  of  Chicago,  knew  of  three 
unpublished  cases,  two  in  which  sponge,  and  one  in 
which  forceps  had  been  left  in  the  abdomen.    To  pre- 


October  4,  1884.] 


THE  MEDICAL  RECORD. 


383 


vent  accident  he  used  a  list  of  instruments  and  sponges, 
and  compared  the  count  after  operations. 

Dr.  John  C.  Reevk,  of  Dayton,  O.,  mentioned  that 
Wilson  used  antiseptic  sponges. 

Dr.  Dunlap,  of  Springfield,  O.,  used  few  instruments 
and  sponges,  and  allowed  no  one  to  put  the  hand  in  the 
abdomen  except  himself.  He  made  the  incision  large 
so  as  to  allow  inspection,  and  used  large  sponges. 

The  discussion  was  continued  by  Drs.  Howard,  of 
Baltimore  ;  Engelmann,  of  St.  Louis  ;  Mund6,  of  New 
York;  Baker,  of  Boston  ;  and  was  closed  by  Dr.  Wilson, 
who  stated  that,  from  discussion  and  from  one  case  learned 
otherwise,  he  could  add  seven  to  those  reported  in  his 
paper ;  making  a  total  of  twenty-eight. 


Tuesday,  September  2oth — First  Day — ^Afternoon 
Session. 

The  Society  was  called  to  order  at  three  o'clock  by 
the  President.^ 

Dr.  C.  D.  Palmer,  of  Cincinnati,  O.,  read  a  paper  on 

ABDOMINAL    SECTION — ITS    VALUE   AND   RANGE  OF   APPLI- 
CATION AS    A   MEANS   OF   DIAGNOSIS   AND   TREATMENT. 

In  no  class  of  diseases  were  there  greater  difficulties 
in  diagnosis  to  be  encountered  than  in  certain  pelvic  and 
abdominal  affections  of  women.  Great  stress  had  been 
laid  upon  the  value  of  tapping  as  a  diagnostic  means. 
Probably  the  middle  ground  of  favor  occupied  by  most 
gynecologists  was  the  correct  one.  But  had  not  the  im- 
portance of  tapping  as  a  means  of  diagnosis  been  exag- 
gerated? The  advantages  offered  by  the  plan  were  men- 
tioned, and  then  reference  was  made  to  the  immense 
damage  that  indiscriminate  tapping  had  done.  Tapping 
should  be  omitted  if  a  diagnosis  could  be  established 
without  it,  or  some  other  equally  risky  procedure.  The 
author  of  the  paper  would  not  assume  the  extreme  posi- 
tion against  i^  but  from  experience  we  were  justified  in 
contending  that  tapping,  in  a  large  proportion  of  cases, 
in  which  it  had  usually  been  practised,  was  unnecessary 
and  superfluous ;  for  diagnosis,  exploratory  section  was 
the  only  means  in  our  possession  to  accurately  determine 
certain  diseases  and  conditions  of  the  pelvis  and  abdo- 
men. After  referring  to  the  views  of  Tait,  Bird,  Atlee, 
Kceberle,  Spencer  Wells,  C.  C.  Lee,  and  his  own  expe- 
rience. Dr.  Palmer  gave  the  general  proposition  that  ab- 
dominal section  was  not  dangerous  in  most  cases,  in 
which  it  appears  justifiable.     That 

THE  RISK  OF  PURE  ABDOMINAL  SECTION  FOR  DIAGNOSIS, 
EXCEPT  IN  MALIGNANT  DISEASES,  IS  LESS  THAN  MIGHT 
BE   EXPECTED. 

In  a  group  of  cases  the  mortality  would  be  heavier 
than  in  completed  operations.  Tait  well  remarked  that 
the  surgeon  should  most  carefully  consider  what  he  was 
about  to  do  before  he  turned  an  exploratory  incision  into 
an  incomplete  operation.  Generally  speaking,  in  all 
seriously  doubtful  and  obscure  cases  of  abdominal  and 
pelvic  disease,  after  other  methods  of  exploration  had 
failed,  and  when  there  were  severe  and  threatening 
symptoms  with  urgent  indications  for  relief,  the  abdomen 
might,  or  should  be,  opened.  The  diseases  in  which  it 
might  be  resorted  to  were  :  First,  ovarian  tumors ;  sec- 
ond, certain  interstitial  and  extrauterine  fibroids  ;  third, 
certain  cases  of  acute  and  chronic  peritonitis  ;  fourth,  in- 
testinal obstruction  ;  fifth,  chronic  pelvic  abscess  ;  sixth, 
extra-uterine  pregnancy.  These  explorative  incisions 
should  be  performed  antiseptically. 

Dr.  Engelmann,  of  St.  Louis,  thought  that  explora- 
tory section  had  been  practised  too  little  in  this  country 
as  a  means  of  diagnosis.  He  regarded  it  as  far  more  safe, 
and  certainly  more  satisfactory,  than  tapping. 

Dr.  MuNDi,  of  New  York,  regarded  exploratory  in- 
cision, in  the  majority  of  cases,  as  rather  a  safe  procedure. 
In  pelvic  abscess  he  would  first  aspirate,  and,  finding  pus, 
make  a  fi-ee  incision. 

Dr.  Wilson,  of  Baltimore,  regarded  every  ovariotomy 


as  an  exploratory  incision,  because  it  was  very  rare  that 
the  operator  knew  when  he  cut  into  the  abdomen  exactly 
what  he  would  find. 

The  discussion  was  continued  by  Drs.  Maury,  of  Mem- 
phis ;  Jackson,  of  Chicago ;  Scott,  of  San  Francisco ;  and 
closed  by  Dr.  Palmer. 

Dr.  p.  F.  MuNDi,  of  New  York,  read  a  paper  entitled 

CERVICAL  FIBROIDS  AS  A  CAUSE  OF  DYSTOCIA,  AND  THEIR 
REMOVAL  BY  VAGINAL   ENUCLEATION. 

The  paper  was  accompanied  by  specimens.  It  con- 
tained comments  concerning  the  frequency  of  the  occur- 
rence of  cervical  fibroids,  being  much  less  frequent  than 
tumors  situated  in  the  body  of  the  uterus.  A  rSsum^  of 
the  literature  of  the  subject,  and  a  history  of  the  case  under 
his  own  care  was  related,  in  which  a  tumor  weighing  three 
pounds  was  removed  by  enucleation  from  the  anterior  lip 
and  a  portion  of  the  body  of  the  uterus  of  a  woman  thirty- 
eight  years  old,  the  mother  of  seven  children.  The  patient 
recovered,  and  when  discharged  from  the  hospital  nothing 
but  thickening  of  the  anterior  lip  of  the  cervix  remained. 

The  meeting  then  adjourned  to  Wednesday  morning. 

The  following  were  the  members  present :  Drs.  Baker, 
of  Boston  \  Browne,  of  Baltimore ;  Byford,  of  Chicago  ; 
Dunlap,  of  Springfield,  O. ;  Engelmann,  of  St.  Louis ; 
Foster,  of  New  York ;  Howard,  of  Baltimore ;  Jackson, 
of  Chicago;  Jenks,  of  Detroit;  Maury,  of  Memphis; 
Reeves,  of  Dayton,  O. ;  Sawyer,  of  Chicago ;  Scott,  of 
San  Francisco ;  Smith,  of  Philadelphia  ;  Vandewarker,  of 
Syracuse ;  Wilson,  of  Baltimore ;  Johnson,  of  Washing- 
ton;  Mund6,  of  New  York;  Richardson,  of  Boston; 
Thomas,  of  New  York. 

Invited  guests :  Drs.  E.  C.  Dudley,  W.  E.  Clark,  F. 
P.  Seeley,  N.  S.  Davis,  of  Chicago ;  P.  McClure,  of  Du- 
buque ;  H.  G.  Dearborn,  of  Nashua,  N.  H. ;  J.  H.  Cars- 
tens,  of  Detroit ;  T.  B.  Harvey,  of  Indianapolis ;  Fritz 
Netzler,  of  Stockholm  ;  F.  Woodbury,  of  Philadelphia ; 
and  Wesley  M.  Carpenter,  of  New  York. 

A  banquet  was  given  by  the  Chicago  Gynecological 
Societ}*  on  Tuesday  evening  at  the  Palmer  House. 

Wednesday,  October   ist — Second   Day — Morning 
Session. 

The  Society  was  called  to  order  by  Dr.  W.  H.  Byford, 
of  Chicago. 

The  following  gentlemen  were  made  members  by  in- 
vitation :  Drs.  W.  H.  Meyers,  Fort  Wa3me ;  J.  H.  Ranch, 
Springfield,  O.;  J.  K.  Bartlett,  Milwaukee;  Liston  H. 
Montgomery,  Chicago ;  T.  A.  Roger,  Montreal ;  William 
Fox,  Milwaukee. 

discussion  on  dr.  mund^'s  paper. 

Dr.  Jenks,  of  Detroit,  reported  a  case  in  which  a 
small  cervical  fibroid  was  present  at  labor,  and  which  he 
enucleated  without  difficulty,  and  labor  proceeded  with- 
out interruption.  He  favored  enucleation,  although  he 
was  a  believer  in  Csesarean  section  if  performed  before 
the  woman  becomes  exhausted. 

Dr.  Byford,  of  Chicago,  said  his  practice  had  been, 
whatever  was  the  size  of  the  tumor,  whether  sessile  or 
pedunculated,  to  wait  until  labor  began,  believing  that 
these  tumors  can  be  removed  as  easily  at  that  time  as  at 
any  other.  Thus  the  danger  of  producing  miscarriage, 
and  consequently  sacrificing  the  child,  was  avoided ;  be- 
sides, in  many  of  these  cases  the  tumor  was  pushed  before 
the  head  and  delivery  completed  without  injury  to  the 
child. 

The  discussion  was  continued  by  Drs.  Wilson,  of 
Baltimore ;  Dunlap,  of  Springfield,  O. ;  Van  De  Warker, 
of  Syracuse ;  Reamy,  of  Cincinnati ;  and  closed  by  Dr. 
Mund^. 

Dr.  T.  Gaillard  Thomas,  of  New  York,  read  a  paper 
on 

EXTRA-tJTERINE  PREGNANCY,  WITH  REPORT  OF  SIX  CASES. 

It  was  sup))lementary  to  a  report  made  two  years  ago. 
Notwithstanding   the  great  advance  made   concerning 


384 


THE  MEDICAL  RECORD. 


[October  4,  igg^. 


early  and  certain  diagnosis,  it  was  far  from  easy.  The 
dictum  of  Depaul,  however,  that  diagnosis  at  third  or 
fourth  month  was  impossible,  must  be  disregarded.  Refer- 
ence was  made  to  experiments  performed  on  rabbits  by 
Leopold,  who  introduced  foetal  rabbits  after  performing 
laparotomy  and  studied  the  changes  which  followed. 
They  had  a  direct  and  favorable  bearing  on  destruction 
of  the  foetus  by  means  of  the  galvanic  current  Leopold 
also  believed  that  recovery  of  patients  after  rupture  of 
the  Fallopian  tube  was  much  more  common  than  gener- 
ally supposed,  a  position  which  Dr.  Thomas  fully  en- 
dorsed. Dr.  Stephen  Rogers,  of  New  York,  twenty 
years  ago  advocated  laparotomy  and  application  of  liga- 
tures for  control  of  hemorrhage  from  rupture  of  blood- 
vessels with  extra-uterine  pregnancy,  but  had  no  experi- 
ence in  the  plan  of  treatment.  Lawson  Tait,  in  January, 
1883,  operated  under  these  circumstances,  and  in  1884 
in  four  additional  cases,  with  four  recoveries  in  all.  Dr. 
Charles  K.  Briddon,  of  New  York,  followed  Tait,  in 
October,  1883,  and  the  history  of  the  case  was  incorpo- 
rated in  his  paper.  Dr.  Thomas'  conclusion  upon  this 
point  was  that  neglect  to  perform  laparotomy  under  such 
circumstances  would  be  criminal.  The  author  of  the 
paper  then  gave  detailed  histories  of  six  additional  cases 
of  extra-uterine  pregnancy  treated  with  the  galvanic  cur- 
rent. 

The  paper  was  discussed  by  Drs.  Mund6,  of  New  York ; 
Harvey,  of  Indianapolis ;  Palmer,  of  Cincinnati ;  Wilson, 
of  Baltimore  ;  Howard,  of  Baltimore ;  Baker,  of  Boston ; 
and  Reamy,  of  Cincinnati 

Dr.  R.  B.  Maury,  of  Memphis,  read  a  paper  entitled 

CASE  OF  TUBAL  PREGNANCY  WITH  RUPTURE  OF  THE  SAC 
AND  REMARKS  CONCERNING  THE  PROPRIETY  OF  LAPA- 
ROTOMY. 

The  case  was  one  of  ruptured  perineum  with  rectocele 
cured  by  the  usual  operations,  and  followed  by  pregnancy 
in  which  there  developed  suddenly  evidence  of  rupture 
of  the  sac  of  extrauterine  pregnancy,  diagnosticated  to 
be  of  the  tubal  variety.  The  patient  recovered..  After 
referring  to  the  views  of  Tait,  Thomas,  and  others,  Dr. 
Maury  submitted  that  even  under  perfect  surgical 
methods,  we  may  never  hope,  as  a  rule,  to  obtain  satis- 
factory results  from  immediate  laparotomy,  and  at  this 
time  it  would  seem  to  be  more  in  accordance  with  sound 
surgical  principles  to  postpone  all  consideration  of  lapa^ 
rotomy  until  the  period  of  shock  had  passed  away. 


Wednesday,  October  ist — Second  Day — Afternoon 
Session. 

The  Society  was  called  to  order  by  Dr.  Jackson,  of 
Chicago. 

Dr.  Christian  Fenger,  of  Chicago,  was  made  a  mem- 
ber by  invitation. 

Dr.  p.  F.  MuNDi  read  a  paper  entitled 

LIMITS   OF   vaginal   HYSTERECTOMY   FOR   CANCER. 

It  was  essentially  a  rejoinder  to  a  paper  by  Dr.  Jackson, 
of  Chicago,  read  at  the  meeting  last  year,  in  which  the 
conclusions  were  reached,  first^  that  a  diagnosis  of  uterine 
cancer  could  not  be  made  sufficiently  early  to  insure  its 
complete  removal  by  extirpation  of  the  uterus  ;  second 
that  when  a  diagnosis  could  be  made  there  was  no  rea- 
sonable hope  for  a  radical  cure,  and  other  methods  of 
treatment  for  ameliorating  sufifering  or  retarding  the  prog- 
ress of  the  disease,  and  prolonging  life,  were  equally 
eflfectual ;  thirds  that  extirpation  of  a  cancerous  uterus 
was  a  dangerous  operation.  The  author  reported  two 
cases  and  exhibited  specimens.  He  then  discussed  the 
propositions  made  by  Jackson  from  a  clinical  and  statis- 
tical point  of  view,  and  reached  substantially  the  following 
conclusions  concerning  the  precise  conditions  in  which 
alone  operation  seems  justifiable :  firsts  absolute  limita- 
tion of  the  cancerous  disease  to  the  uterus ;  second^  the 
probability  of  a  complete  removal  of  the  disease  by  high 


supravaginal  amputation  and  cautery,  questionable* 
third,  cancer  or  sarcoma  of  the  body  of  the  utenis- 
fourth^  perfect  freedom  of  motion  of  the  uterus ;  fifth 
capacious  vagina;  sixths  sufficiently  vigorous  condition 
of  the  general  system.  What  he  wished  to  accomplish  by 
the  paper  was  to  protest  against  wholesale  condemnation 
of  a  perfectly  radical  surgical  measure  on  the  more  or 
less  theoretical  ground  that  it  is  too  dangerous  and  not 
sufficiently  beneficial,  when  facts,  as  shown  by  statistics, 
prove  to  the  contrary,  and  to  claim  for  the  operation  cer- 
tain justification. 

Dr.  Jackson,  of  Chicago,  maintained  that  surgical 
procedure,  to  be  justifiable,  should  alleviate  sufifering  and 
prolong  life.  The  operation  under  consideration  did 
neither  of  these,  and  therefore  was  unjustifiable  without 
regard  to  special  cases. 

Dr.  Van  De  Warker,  of  Syracuse,  said  the  question 
was  not  how  many  died  and  how  many  recovered  after 
operation,  but  was  there  any  better  way  to  reach  the 
same  result?  He  believed  there  were  other  methods 
which  were  safer  and  equally  as  competent  as  the  use  of 
the  knife. 

Dr.  Engelmann,  of  St.  Louis,  argued  in  favor  of 
operation,  and  claimed  that  the  success  already  obtained 
warranted  its  continuation  until  more  fully  tested. 

Dr.  Palmer,  of  Cincinnati,  thought  that  vagnial 
hysterectomy  was  not  applicable  in  cases  in  which  cancer 
had  its  starting-point  in  the  cervix. 

Dr.  Baker,  of  Boston,  sustained  the  operation  as 
justifiable. 

Dr.  Scott,  of  San  Francisco,  thought  young  fellows 
were  arranged  upon  one  side  and  old  fellows  upon  the 
other. 

Dr.  Reamy,  of  Cincinnati,  thought  statistics  did  not 
prove,  nor  did  the  paper  prove,  that  operation  prolonged 
life  or  cured  the  disease,  or  from  a  clinical  standard  that 
it  was  justifiable. 

The  discussion  was  continued  by  Dr.  Ferger,  of  Chi- 
cago, and  closed  by  Dr.  Mund6. 

The  Society  then  adjourned  to  Thursday  morning. 

Thursday,  October  2D — Third  Day — Morning 
Session. 

The  delivery  of  the  President's  address  on  the  present 
aspect  of  the  puerperal  diseases  was  postponed  on  ac* 
count  of  the  sickness  of  the  President. 

Dr.  Edward  Sawyer,  of  Chicago,  read  a  paper  on 
"  Occipito-posterior  Position  in  Vertex  Labors."  A 
paper  was  also  read  on  *'  Rare  and  Fatal  Form  of  Sepsis 
without  Symptoms,"  by  Dr.  G.  J.  Engelmann,  of  St 
Louis. 

PAPERS  READ  BY  TITLE  : 

"Hygiene  of  Pregnancy,'*  by  Dr.  S.  C.  Busey,  of 
Washington ;  "  Rapid  Dilation  of  Cervical  Canal,"  by 
Dr.  William  Goodell,  of  Philadelphia  ;  **  Physiognomy 
of  Vulva  a  Sequence  of  Anal  Disease,"  by  Dr.  Isaac  E. 
Taylor,  of  New  York  ;  "  Early  History  of  the  Treatment 
of  Vesico-Vaginal  Fistula  in  the  United  States,"  by  Dr. 
Nathan  Bozeman,  of  New  York  ;  **  Periodical  S)rmptoms 
in  Uterine  Disease,"  by  Dr.  G.  J.  Engelmann,  of  St, 
Louis ;  "  Topography  and  Sectional  Anatomy  of  the  Fe- 
male Pelvis,"  by  D.  B.  Hart,  of  Edinburgh;  "  Fibro- 
Myomata  of  the  Uterus,"  by  Dr.  R.  S.  Sutton,  of  Pitts- 
burg. 

The  following  officers  were  elected :  President — Will- 
iam T.  Howard,  Baltimore,  Md. ;  Vice-Presidents — W. 
L.  Richardson,  Boston,  Mass.,  and  Paul  F.  Mund6,  New 
York  ;  Secretary — Frank  P.  Foster,  New  York ;  Treas- 
urer— Matthew  D.  Mann,  Buffalo,  N.  Y. ;  Members  of 
Council — A.  Reeves  Jackson,  Chicago,  111.  ;  H.  P. 
C.  Wilson,  Baltimore,  Md.;  Joseph  Tabor  Johnson, 
Washington,  D.  C;  Ely  Van  De  Warker,  Syracuse,  N.  Y. 

The  next  meeting  will  take  place  at  Washington,]  D. 
C,  on  the  third  Tuesday  in  September,  1885. 


October  4i  1884.] 


THE  MEDICAL  RECORD. 


385 


THE  HOSPITALS   MEDICAL   SOCIETY   OF 
PARIS. 

Stated  Meeting,  July  25,  1884. 

M.  BucQUOY,  President,  in  the  Chair. 

(Special  Report  for  Thb  Mbxmcal  Rbcokd.) 

The  Society  having  been  called  to  order  by  the  Presi- 
dent, M.  Martineau  rose  to  state  his  views  upon  the 
relations  of 

syphilis  and  Choi^era, 
and  the  influence  exerted  upon  the  latter  by  the  former 
affection.  It  had  been  asserted  that  the  mercury  given 
in  the  treatment  of  syphilis,  especially  the  biniodide  of 
mercury,  acted  also  as  one  of  the  best  prophylactics 
against  cholera.  The  speaker  opposed  this  view,  and 
stated  that  of  nine  fatal  cases  of  cholera  occurring  during 
the  epidemic  of  1849  ^^  ^^  H6pital  de  Lourcine,  eight 
o{  the  patients  were  under  treatment  for  syphilis.  A 
similar  experience  obtained  in  1866.  At  that  time  two 
wards  were  devoted  to  the  reception  of  cholera  patients, 
but  the  disease  spread  throughout  the  hospital  and  at- 
tacked by  preference  the  syphilitics. 

M.  Dujardin-Beaumetz  had  observed  the  same  un- 
toward results  in  the  case  of 

syphilis  and  typhoid  fever. 

It  had  become  a  common  saying  in  the  H6pital  Co- 
chin  that  a  patient  in  the  early  stage  of  syphilis,  if 
attacked  by  typhoid,  fever,  was  a  doomed  man.  Thus 
the  mercury  was  seen  to  fail  likewise  in  this  disease.  It 
was  true,  as  stated  by  Miquel,  that  the  biniodide  of  mer- 
cury was  a  most  powerful  disinfectant.  But  it  was  very 
unsafe  to  reason  that,  because  a  certain  dnig  acted  as  a 
microbicide  in  the  test-tube,  it  would  act  similarly  in  the 
human  organism. 

M.  BucQUOY  agreed  with  the  last  speaker  as  to  the 
gravity  of  typhoid  fever  when  it  attacked  a  patient  al- 
ready suffering  from  syphilis. 

M.  Damaschino  recalled  several  fatal  cases  of  cholera 
occurring  in  syphilitic  patients  during  the  epidemic  of 
1866. 

M.  F£r£ol  regarded  syphilis  and  cholera  as  a  com- 
bmation  of  great  gravity,  but  could  not  entirely  agree 
r  with  the  last  speakers  as  regards  the  evil  influence  of 
syphilis  upon  the  course  of  typhoid  fever.  He  had  seen 
a  number  of  cases  of  this  kind  in  which  recovery  took 
place. 

M.  Vallin  exhibited  a 

^  chamberland's  water  filter 
made  after  the  model  of  that  used  by  Pasteur  in  his  la- 
boratory. Two  cylinders  are  placed  one  within  the  other, 
the  inner  one  being  made  of  porcelain  and  being  the 
filter  proper.  A  pressure  of  one  atmosphere  and  a  half 
was  necessary  to  force  the  water  through  the  sides  of  the 
cylinder.  The  water  was  cleared  absolutely  of  all  sus- 
pended matters.  The  filter  could  be  readily  taken  apart 
and  purified  by  passing  the  inner  cylinder  through  a 
flame. 

M.  GiRiN-RozE  thought  the  objection  to  such  a  filter 
was  that  it  removed  the  suspended  particles,  but  not  the 
matters  held  in  solution.  He  preferred  a  charcoal  filter, 
even  though  it  might  be  a  little  more  complicated  and 
difficult  to  cleanse. 

M.  Dujardin-Beaumetz  presented  a  young  man  in 
whom  there  was  a 

transposition  of  the  viscera. 

The  patient  had  had  a  pleurisy  with  efliision,  and  the 
heart-sounds  were  heard  on  the  right  side.  But  after 
the  pleurisy  was  cured  the  heart  still  remained  on  this 
side,  and  it  was  then  that  the  fact  of  the  transposition  of 
the  viscera  was  noted. 

M.  BuCQUOY  had  observed  a  similar  state  of  affairs  in 
a  woman.  In  this  case  the  patient  herself  called  atten- 
tion to  the  fact  that  her  liver  was  on  the  left  side. 


M.  Damaschino  presented  a  co mm imi cation  on  the 

distoma  h^matobium 

offered  by  a  physician  of  Alexandria.    The  microscopical 

preparations  which  accompanied  the  paper   were  from 

cases  of  distoma  of  the  liver  and  of  the  kidneys. 

M.  Dujardin-Beaumetz  then  read  a  paper  on  the 

diagnosis  of  cancer  of  the  stomach. 

His  object  was  to  call  attention  especially  to  the  diffi* 
culties  of  a  correct  diagnosis.  There  was  indeed  no  cer- 
tain pathognomonic  symptom  of  carcinoma  of  the  stomach. 
In  the  first  place,  we  are  usually  unable  to  determine  the 
exact  nature  of  any  internal  tumor.  Histology  has  given 
us  a  very  complete  list  of  the  various  forms  of  cancer, 
but  clinically  we  can  make  no  such  fine  distinctions. 

It  has  been  asserted  that  the  duration  of  carcinoma  is 
shorter  than  is  that  of  other  chronic  affections  of  the 
stomach,  three  years  being  given  as  the  maximum.  But 
while  this  might  be  true  of  some  varieties  of  cancer,  it 
was  not  so  of  all.  The  author  recalled  one  case  of  un- 
doubted carcinoma,  as  proved  by  autopsyj  in  which  the 
earliest  symptoms  preceded  death  by  twelve  years.  It 
might  be  objected  that  the  case  was  one  of  cancer  fol- 
lowing ulcer  of  the  stomachy  and  that  the  earlier  synip- 
toms  were  those  of  the  latter  affection.  Such  an  assump- 
tion was,  however,  gratuitous,  and,  besides,  the  author 
had  seen  other  cases  in  which  the  duration,  though 
shorter  than  in  the  instance  just  cited,  yet  exceeded 
greatly  that  usually  set  down  for  carcinoma. 

The  diagnosis  between  cancer  and  dilatation  of  the 
stomach  was  a  matter  of  considerable  difficulty.  As  re- 
gards sex,  men  are  more  subject  to  cancer,  and  so  they 
are  to  dilatation.  Both  affections  are  met  with  usually  at 
about  the  age  of  forty  years.  Qiiesnel's  assertion,  that 
every  cachectic  person  suffering  froju  a  chronic  affection 
of  the  stomach  has  carcinoma,  cannot  be  maintained. 
And  even  painful  oedema  of  the  legs,  regarded  by  Trous- 
seau as  characteristic  of  cancer,  may  occur  with  simple 
dilatation.  Pain  is  not  a  symptom  of  any  great  value, 
for  although  it  usually  exists  it  may  also  be  absent.  The 
vomiting  of  coffee-ground  matters,  formerly  regarded  as 
pathognomonic  of  cancer,  may  occur  in  dilatation,  and  is 
therefore  a  sign  of  no  exceeding  value.  Even  the  exist- 
ence of  a  tumor  may  be  misleading,  for  a  thickening  of 
the  stomach  walls  may  occur  in  dilatation  and  may  be 
mistaken  for  cancer.  If,  however,  the  tumor  be  well 
defined  stnd  lobulated,  the  diagnosis  of  cancer  is  rendered 
fairly  certain.  The  German  method  of  setting  free  a 
large  quantity  of  gas  in  the  stomach,  the  author  con- 
sidered to  be  practically  of  no  value  in  diagnosis.  It 
has  been  asserted  that  in  the  case  of  cancer  the  hydro- 
chloric acid  is  wanting  in  the  gastric  juice,  but  this  is 
equally  inapplicable  and  valueless  in  practice. 

M.  Romelare,  of  Brussels,  had  noted  a  fact  which  M, 
Dujardin-Beaumetz  thought  might  prove  useful  in  this 
connection.  He  had  found  that  in  cancerous  affections 
of  the  stomach  and  liver  the  amount  of  urea  excreted 
was  reduced  to  an  average  of  1 30  grains,  and  never  ex- 
ceeded 150  grains  in  the  twenty-four  hours.  In  the  case 
of  ulcer  of  the  stomach,  on  the  other  hand,  the  amount 
of  urea  ranged  from  250  to  500  grains,  and  never  fell 
below  225  grains  per  diem.  The  author  had  verified 
these  conclusions  in  a  general  way,  yet  they  were  not 
entirely  reliable  as  a  means  of  diagnosis.  He  had  had  a 
patient  in  whom  the  daily  amount  of  urea  excreted  was 
but  45  grains,  and  had  therefore  concluded  chat  the 
disease  was  cancer,  but  found  at  the  autopsy  that  the 
tumor  was  an  h)'datid  cyst.  There  was  stiLl  another 
procedure  which  might  be  of  assistance  in  establishing  a 
diagnosis.  He  had  procured  an  amelioration,  and  even 
a  temporary  lull,  in  the  symptoms  by  regular  and  methodi- 
cal washing  out  of  the  stomach  in  the  case  of  carcinoma. 
In  the  case  of  dilatation,  however,  no  improvement  was 
obtained  by  this  practice. 

Upon  the  conclusion  of  this  paper  the  Society  ad* 
journed. 


586 


THE   MEDICAL   RECORD. 


THE  THERAPEUTICAL    SOCIETY    OF   PARIS, 

Siaied  Meeting,  Juiy  2  ^y  1S84. 
M»  Delpech,  President,  in  the  Chair. 

ISpecA]  Rcpcui  for  The  Mkimcal  Recoup.) 

When  the  Society  had  been  called  to  order  there  arose 
a  short 

DISCtJSEION  ON   ANTISEPTICS. 

M,  Di;jaroin-Beaumetz  thought  that  the  toxic  nature 
of  any  substance  should  be  considered  as  well  as  its 
antiseptic  powers,  A  drug  might  be  a  perfect  micro- 
bicide^  but  might  also  be  practically  useless  because  of 
Us  strongly  poisonous  quaUties.  The  best  antiseptic 
was  undoubtedly  that  which  was  the  least  harmful  to 
man  in  the  dose  required  for  asepsis.  He  regarded 
boracic  acid  and  borax  as  the  best  microbicides  for  in- 
ternal use  that  we  possessed,  as  they  combined  at  the 
same  time  a  high  degree  of  antiseptic  power  with  an 
almost  complete  absence  of  injurious  properties  to  the 
human  subject. 

M,  BRf  MOND  spoke  in  glowing  terms  of 

OZONE 

as  the  best  disinfectant  of  the  air  in  sleeping  apartments 
and  other  enclosed  spaces.  A  sufficient  quantity  of  this 
substance  may  be  produced  with  great  ease  by  using  a 
spray  of  spirits  of  tuq>entine, 

M,  Limousin  stated  that  by  making  a  mixture  of  per- 
manganate of  potash  and  bisulphate  of  potash  and  ex- 
posing it  to  the  action  of  damp  air  we  could  obtain  a  con- 
stant formation  of  oione.  The  making  of  ozone  by  pouring 
sulphuric  acid  upon  the  permanganate  of  potash  was  liable 
to  cause  an  explosion,  especially  if  a  closed  flask  were 
used.  The  mixture  recommended  by  him  was  firee  from 
danger  of  this  kind-  When  ozone  was  prepared  by 
means  of  the  electric  spark,  an  odor  was  noticeable 
which  was  absent  when  the  permanganate  and  the  bisul- 
phate of  potash  were  usedj  yet  the  substance  was  un- 
doubtedly obtained  equally  well  by  the  latter  method. 

M,  Djjardin-Beaumetz  gave  the  substance  of  a  com- 
municadon  which  he  had  presented  to  the  Bureau  of 
Hygiene  on  the  best  method  of  preparing 

A     drink:     for     school-children     DURING     THE     HOT 
WEATHER. 

A  beverage  of  this  kind  should  be  healthful,  cheap,  and 
at  the  same  time  not  very  pleasant  to  the  taste,  as  it 
might  then  be  consumed  in  too  large  quantities.  These 
qualities  were  possessed  by  a  liquid  containing  gentian 
or  quassia,  licorice,  mint,  sugar,  and  citric  acid.  Its 
preparation  cost  about  a  cent  a  quart. 

M»  Campardon  said  that  thirst  might  be  easily  as- 
suaged  by  chewing  shavings  of  quassia  wood  occasionally. 

M.  Blonde AU  made  a  statement  concerning  the 
value  of 

SULPHURIC  ACID   IN    CHOLERA* 

He  said  that  during  the  last  epidemic  in  England  very 
general  use  was  made  in  some  places  of  sulphuric  acid 
lemonade  flavored  with  tincture  of  orange  peel,  and  not 
one  of  those  who  took  this  regularly  was  attacked  by 
cholera, 

M^  Limousin  said  that  there  were  several  chemically 
incompatible  formula  published  by  the  Bureau  of  Hy- 
giene.  Sweet  and  bitter  substances  were  added  to  acids 
and  alkalies  in  a  hap-hazard  sort  of  way.  It  would  seem 
as  though  such  mixtures  ought  to  be  useless.  Vet  if,  in 
practice,  the  desired  result  is  obtained,  we  ought  to  be 
satisfied. 

M.  BucQUOY  regretted  to  hear  the  use  of  boiled  water 
recommended.  This  was  not  healthful  and  was  hable  to 
cause  digestive  troubles. 

M.  JJujardin-Beaumetz  said  that  the  boiled  water 
could  be  recharged  with  air  by  shaking  it,  but  it  was 
evident  that  jn  this  process  it  would  also  become  charged 
with  the  germs  tloating  in  the  atmosphere. 


This  was  the  last  meeting  Fof  the  Society  before  tiie 
summer  vacation,  but  the  President  announced  that 
special  meetings  would  be  called  from  time  to. time,  if 
events  of  importance  requiring  discussion  should  arise. 
The  Society  then  adjourned  subject  to  the  call  of  the 
President. 

THE  SURGICAL  SOCIETY  OF  PARIS. 

Stated  Meeting,  July  23,  1884. 
M.  Marc  Si:E,  President,  in  the  Chair. 

(Specul  Ropcirt  fbr  TttK  Medical  Rkcosd.) 

The  Society  having  been  called  to  order  by  the  Presi- 
dent, M.  MoNOD  recalled  a  paper,  read  at  the  last  meet- 
ing, on  exostoses  of  the  frontal  sinus,  and  related  an 
instance  in  which  an 

OSSEOUS   CVST  OF  THE    FRONTAL   SINUS 

had  been  taken  for  an  exostosis.  Dr.  Rouge,  thinking 
that  such  was  the  case^  cut  down  upon  it  and  was  sur- 
prised to  find  himself  in  a  cavity  with  very  thick  bony 
walls,  at  the  bottom  of  which  was  a  little  tumor  about 
the  size  of  a  cherry.  The  tumor  was  not  disturbed,  and 
had  not  increased  any  in  size  in  the  fourteen  years  whid 
had  since  elapsed. 

M.  Tr^lat  requested  that  further  details  of  this  case 
be  obtained,  so  that  a  certain  diagnosis  might  be  estab- 
lished 

M.  CHAtJVEL  then  read  a  report  upon  a  monograph  of 
Dr.  Poulet  on  the  subject  of 

TUBERCULAR  AND   SYPHILITIC   OSTEITES    OF  THE  SKULU 

The  author  passed  briefly  in  review  the  subject  of  simple 
traumatic  osteitis,  the  characters  of  which  it  is  easy  to 
reproduce  experimentally  in  animals,  and  then  took  up 
the  question  of  the  specific  forms  of  osteitis,  especially 
the  tubercular  and  the  syphilitic.  Although  osseous 
tuberculosis  is  a  common  enough  affection,  tubercle  of 
the  cranial  bones  is,  if  one  may  judge  from  the  number 
of  reported  cases,  a  very  rare  condition.  M.  Poulet, 
however,  claimed  to  have  found  two  instances  of  this 
disease  among  the  specimens  in  the  museum  of  Val-de- 
Grace,  but  the  reporter  took  the  liberty  of  doubting  this 
until  further  proof  should  be  forthcoming.  The  author 
endeavored  to  show  that  this  affection  was  most  truly 
specific,  as  well  in  its  symptoms  as  in  its  pathological 
characteristic's.  The  specific  nature  of  the  second 
variety  of  osteitis,  the  syphilitic,  was  incontestable.  M, 
Poulet  was  able  to  show  from  a  careful  examination  of 
numerous  pathological  specimens  that  the  course  of  the 
disease  was  always  the  same.  Starting  from  the  peri- 
cranium, the  gummy  process  invades  the  bone  in  the 
form  of  a  spiral  the  turns  of  which  become  constantly 
larger.  In  tiie  skull  this  spiral  increases  laterally  like  a 
watch-spring,  while  in  the  long  bones  of  the  extremities 
it  increases  in  depth  like  a  corkscrew.  The  border  of 
this  spiral  is  formed  of  very  dense,  eburnated  bone.  The 
monograph  was  accompanied  wiA  a  number  of  well-exe- 
cuted designs  showing  the  lesions  referred  to. 
M.  BouiLLY  then  read  the  history  of  a  case  of 

PAROVARIAN   CYST  OF  THE   RIGHT   SIDE 

reported  by  Dr.  Jeaunel.  The  patient,  thirty-five  years 
of  age,  in  a  good  state  of  health,  presented  the  signs  of 
a  monolocular  cyst  of  the  ovary.  The  aspirator  was 
introduced  and  nearly  sixty  ounces  of  a  perfectly  clear 
fluid  were  withdrawn.  Three  months  later  a  second  op- 
eration was  necessitated  by  reason  of  a  reaccumulation 
of  fluid.  After  aspiration  of  about  seventy  ounces  of 
fluid,  the  sac  was  washed  out  with  thirty  ounces  of  a  one 
per  cent,  carbolic  acid  solution.  Then  an  injection  of  a 
warm  solution  of  tincture  of  iodine  and  water,  equal 
parts,  was  thrown  into  the  cavity £of  the  cysL  When 
nearly  nineteen  ounces  of  this  mixture  had  been  injected, 
the  action  of  the  aspirator  was  reversed  in  order  to  draw 


October  4,  1884.] 


THE  MEDICAL  RECORD. 


387 


the  fluid  back ;  but  not  a  drop  returned.  At  the  same 
time  the  patient  became  unconscious,  though  very  rest- 
less; the  face  was  blue,  the  pulse  at  the  wrist  was  almost 
imperceptible,  and  the  body  was  covered  with  a  sticky 
perspiration.  The  respirations  were  slow,  irregular,  and 
noisy.    The  woman  was  suffering  most  evidently  from 

ACUTE   IODINE-POISONING. 

The  aspirator  needle  was  withdrawn  and  reintroduced 
several  times  but  no  fluid  could  be  drawn  off.  Numerous 
hypodermic  injections  of  ether  were  made,  mustard 
plasters  were  applied  to  the  chest,  and  an  electric  bat- 
tery of  forty  cells  was  employed.  But  the  patient  did 
not  recover  cpnsciousness  and  the  power  of  speech  until 
thirty-five  hours  had  elapsed.  She  then  suflfered  from 
very  marked  symptoms  of  iodism  in  all  the  mucous 
membranes,  the  symptoms  persbting  for  two  weeks  or 
more. 

The  author  emphasized  the  fact,  as  shown  by  this  case, 
that  very  grave  accidents  may  follow  an  operation  appar- 
ently so  simple  as  this.  He  thought  it  would  have  been 
better  for  the  patient  had  ovariotomy  been  performed  in 
the  first  place.  M.  Bouilly  agreed  with  him  in  this  last 
conclusion,  and  remarked  that  this  case  proved  that,  con- 
trary to  the  generally  received  opinion,  parovarian  cysts 
were  not  always  cured  by  a  single  puncture. 

M.  TiLLAUX  could  not  understand  why  the  aspirator 
should  be  used  in  cases  of  this  kind,  for  it  only  favored 
an  arrest  of  the  stream,  as  happened  in  this  instance,  by 
sucking  the  wall  of  the  cyst  against  the  point  of  the 
needle.  He  thought  the  amount  of  tincture  of  iodine 
injected  (over  nine  ounces)  was  enormous.  The  formula 
that  had  been  recommended  for  use  in  such  injections 
was  one  part  tincture  of  iodine  to  two  parts  of  water. 

M.  Lucas  ChampioniIsre  favored  operation  in  the 
treatment  of  parovarian  cysts.  In  the  case  cited  by  M. 
Jeaunel,  the  patient  had  undergone  a  number  of  opera- 
tions more  serious  in  the  aggregate  than  ovariotomy,  and 
yet  she  was  not  radically  cured. 

M.  BouiLLY  thought  that  the  amount  of  iodine  used 
was  certainly  too  great,  but  he  thought  the  symptoms 
were  not  those  of  poisoning,  but  were  caused  rather  by 
the  traumatism  of  the  operative  measures  employed.  He 
did  not  agree  with  the  last  speaker  in  his  preference  for 
ovariotomy.  He  thought  it  better  to  make  one  or  two 
ponctures  at  least  before  resorting  to  operation. 

He  then  read  another  report  on  a  paper  by  Dr.  Leriche, 
entitled 

THREE   SUCCESSFUL  OVARIOTOMIES. 

In  two  of  the  cases  the  pedicle  was  fastened  externally, 
instead  of  being  abandoned  in  the  abdominal  cavities,  as 
is  usually  done.  He  did  not  favor  catgut  for  ligatures,  as 
it  could  not  be  drawn  tightly  enough. 

M.  TiLLAUX  had  formerly  used  catgut,  but  had  aban- 
doned it  for  silk  after  having  lost  a  patient  from  hemor- 
rhage caused  by  the  slipping  of  the  ligature. 

After  some  further  discussion  on  the  relative  merits  of 
catgut  and  carbolized  silk,  M.  Verneuil  related  a  case  of 

naso-pharyngeal  polypus. 

The  patient  had  been  exhibited  at  a  meeting  of  the 
Society  four  months  ago.  He  was  then  suffering  from 
an  enormous  recurrent  tumor,  the  first  operation  (removal 
of  the  upper  jaw)  having  been  performed  one  year  before. 
The  tumor  was  exceedingly  vascular,  and  a  bruit  was 
distinctly  audible.  The  attempt  was  first  made  to  treat 
it  by  means  of  irritant  injections,  but  these  were  without 
result  It  was  then  decided  to  tie  the  common  carotid. 
This  was  easily  done  and  was  followed  by  reduction  in 
aze  of  the  tumor,  subsidence  of  inflammation,  and  relief 
from  pain.  A  small  abscess  formed,  however,  at  the  point 
of  incision,  and  was  opened  by  M.  Kirmisson,  and  a 
drainage-tube  was  inserted.  The  opening  did  not  cica- 
trize, and  six  weeks  after  the  ligation  of  the  artery  the 
pat  cnt  had  an  attack  of  erysipelas.  This  was  recovered 
froii,  but  the  wound  began  to  slough,  and  a  number  of 


hemorrhages  occurred  from  which  the  patient  finally  suc- 
cumbed. 

At  the  autopsy  there  was  found  to  be  perforation  at  the 
bottom  of  the  sphenoidal  fossa,  through  which  a  lobe  of 
the  tumor  had  passed  into  the  cranial  cavity.  There 
had,  however,  never  been  any  cerebral  symptoms.  The 
peripheral  extremity  of  the  carotid  artery  was  completely 
occluded,  but  it  required  a  long  search  before  the  string- 
like remains  of  the  cardiac  extremity  could  be  found. 

M.  TRiLAT  thought  that  palliative  operations  might  lead 
to  a  perfect  cure  of  naso-pharyngeal  polypi,  as  many  of 
these  tumors  underwent  spontaneous  disappearance  m 
the  course  of  time. 

M.  Lucas  Championi^re  said  that,  accordmg  to  Lis- 
ter, arteries  should  never  be  tied  with  silk,  but  with  ^me 
substance  which  is  capable  of  being  absorbed  m  the 
tissues.  The  case  just  related  emphasized  the  wisdom  of 
this  procedure,  for  no  wound  in  which  a  silk  ligature 
remains  can  be  with  absolute  certainty  aseptic. 

M.  TiLLAUX  presented  a  patient  upon  whom  he  had 
performed 

RESECTION  OF  THE    SUPERIOR   MAXILLA 

on  account  of  a  sarcomatous  tumor,  the  size  of  a  small 
ostrich  egg,  filling  the  entire  zygomatic  fossa.  The  pa- 
tient made  an  excellent  recovery,  and,  by  means  of  an 
apparatus  made  by  M.  Beauregard,  could  masticate  with 
great  ease. 

The  meeting  then  adjourned. 


%nt0vxmtianva  |PejflicaX  (S^ugkzss. 

EIGHTH   SESSION. 
Held  at  Copenhagen,  Denmark,  August  10-16,  1884. 

REPORTS   OF   SECTIONS. 
(Special  Report  for  Thb  Mbdical  Rbcord.) 
SECTION    ON    OPHTHALMOLOGY. 
Dr.  Samelsohn,  of  Cologne,  read  a  paper  on  the 

PRACTICAL  VALUE   OF    LIGHT  SENSE    IN   OPHTHALMOLOGY. 

If  the  examination  of  the  light  sense  in  practical 
ophthalmology  has  not  hitherto  met  with  the  attention 
it  undoubtedly  deserves,  it  is  from  the  want  of  an  effi- 
cient mode  of  testing  it  The  methods  hitherto  in  use 
depend  on  testing  the  vision  either  with  diminishing  or 
with  constant  illumination.  The  first  method  was  much 
used  by  Forster,  who  formulated  the  law  that  the  light 
sense  is  only  impaired  in  affections  of  the  percipient 
elements,  while  affections  of  the  conducting  elements 
are  indicated  rather  by  an  increased  sensibility  for  ob- 
jective light.  A  large  number  of  examinations  made 
during  the  last  two  years  have  convinced  the  autfior 
that  the  law  of  Forster  has  only  a  very  limited  applica- 
tion. 

Although  disease  of  the  percipient  elements  of  the 
retina  very  often  results  in  a  considerable  impairment  of 
the  light  sense,  yet  the  converse  is  not  so  often  true 
that  one  can,  from  the  fact  of  the  light  sense  being  im- 
paired, diagnose  a  disease  of  the  percipient  elements. 
Indeed,  inflammatory  affections  of  the  optic  nerve  cause 
so  great  a  diminution  of  the  light  sense  that  m  certam 
aflfections  it  amounts  almost  to  torpor  of  the  retina. 

DESCRIPTION   OF  THE   CONDITION   IN   CERTAIN   FORMS   OF 
DISEASE. 

From  this  it  is  seen  that  the  li^ht  sense  is  very  much 
more  aflfected  than  the  quantitative  color  sense ;  the 
latter,  on  the  conti-ary  fas  shown  elsewhere),  stands  in 
the  clearest  numerical  relation  with  the  light  sense.  The 
testing  of  the  light  sense  is  useful  for  differential  diag- 
nosis under  the  following  circumstances  :  (i)  In  certain 
forms  of  opacities  of  vitreous,  which  may  be  mistaken 
for  detachment  of  the  retina ;  (2)  in  differential  diag- 


m 


THE  MEDICAL  RECORD. 


[October  4,  1884. 


nbsis  between  simple  glaucoma  and  optic  atrophy;  (3) 
as  giving  indication  for  diagnosis  and  prognosis  in  cer- 
tain forms  of  cataract. 

Prof.  Schmidt-Rimpler,  of  Marburg,  read  a  paper  on 

A  NEW  METHOD  OF  DETERMINING  REFRACTION  BY  MEANS 
OP  THE   OPHTHALMOSCOPE. 

In  this  method  he  did  not  make  use  of  the  image  of  the 
retina  itself,  but  observed  the  image  of  the  source  of  light 
(lamp)  thrown  upon  the  fundus,  the  same  image  that 
forms  the  object  of  investigation  in  so-called  retinoscopy, 
except  that  in  the  latter  no  convex  lens  intervenes.  The 
apparatus  used  in  Professor  Schmidt-Rimpler's  method 
consists  of  a  convex  lens,  from  which  an  ^m  projects  to 
keep  it  at  such  a  distance  from  the  observed  eye  that  its 
focus  and  the  first  principal  point  of  the  eye  coincide. 
A  tape  measure  on  the  opposite  side  of  the  lens  deter- 
mines the  distance  of  this  lens  from  the  concave  ophthal- 
lyioscopic  mirrors,  from  which  data  the  distance  between 
the  principal  focus  of  the  lens  and  the  inverted  image  of 
the  source  of  light  reflected  from  the  concave  mirrors  is 
known.  This  distance,  expressed  in  centimetres,  gives 
the  amount  of  ametropia  in  terras  of  a  dioptric,  myopia 
to  the  one  side  of  the  focus  of  the  lens,  and  hypermetropia 
to  the  other.  It  was  plain  that  if  the  eye  examined  were 
emmetropic,  and  its  accommodation  at  rest,  the  best  de- 
fined image  of  the  source  of  light  would  be  obtained  when 
the  focus  of  the  concave  mirror  coincided  with  that  of  the 
contex  lens,  as  it  was  at  that  point  that  the  inverted 
atrial  image  of  the  fundus  was  situated.  In  myopia  the 
focus  of  the  concave  mirror  must  lie  nearer  to  the  lens 
'  than  the  focal  length  of  the  lens,  in  order  to  obtain  the 
best  definition,  and  in  hypermetropia  it  must  lie  further 
from  the  lens  than  the  focus  of  the  latter.  When  the 
lens  was  so  placed  that  its  focus  coincided  with  the  prin- 
cipal point  of  the  eye,  equal  movements  of  the  external 
source  of  light  along  the  optic  axis  corresponded  to  equal 
differences  of  refraction  in  the  observed  eye.  The  strength 
of  lens  used  was  10  D,  and  in  that  case  every  alteration 
in  the  refraction  amounting  to  i  D  altered  the  position  of 
the  aerial  image  of  the  fundus  i  centimetre. 

Dr.  Noyes,  of  New  York,  did  not  rely  entirely  upon 
the  ophthalmoscope ;  he  always  tried  the  use  of  glasses  in 
confirming  his  diagnosis.  He  had  a  clip  upon  his  own 
ophthalmoscope  in  which  he  could  easily  place  a  cylindri- 
cal lens  for  examining  the  fundus. 

Mr.  Berry,  of  Edinburgh,  approved  of  Professor 
Schmidt-Rimpler's  method  because  of  the  difficulty  of 
testing  by  the  direct  method  in  Aigh  degrees  of  ametropia. 
He  had  found  that  the  refraction  of  the  eye  was  different 
at  the  yellow-spot  and  the  optic  disk  regions. 

Mr.  Yuler,  of  London,  said  that  he  should  be  glad  to 
become  practically  acquainted  with  Professor  Schmidt- 
Rimpler's  new  method.  With  regard  to  the  estimation 
of  refraction  by  the  direct  method  of  ophthalmoscopic 
examination,  he  was  of  the  same  opinion  as  Mr.  Berry 
and  Dr.  Noyes,  viz.,  that  in  simple  hypermetropia  and 
myopia  of  low  degree  we  were  able  to  see  the  yellow- 
spot  region,  and  so  to  estimate  the  refraction  on  the 
visual  axis ;  but  when  astigmatism  existed,  the  direct 
method  failed  because  of  the  paucity  of  vessels  in  the 
yellow-spot  region.  He  considered  the  shadow-test  (re- 
tinoscopy) to  be  the  best  and  most  exact  means  of  esti- 
mating the  refraction  in  astigmatism,  but  this  must  be 
done  only  when  the  eye  is  fully  atropised  and  the  patient 
is  looking  straight  at  the  observer's  forehead.  By  this 
means  the  refraction  of  the  visual  axis  could  be  accu- 
rately estimated. 

Dr.  Hansen  Grut,  Prof.  Sattler,  and  Prof.  Liebrecht 
also  joined  in  the  discussion,  and  Prof.  Schmidt-Rimpler 
replied. 

Dr.  Edm.  Hansen  Grut,  of  Copenhagen,  read  a 
paper  on 

TWO    FORMS   OF   KERATITIS. 

I.  The  first  form  was  bullous  keratitis  following  trau- 
matic abrasions  of  the  corneal  epithelium.     The  painful 


and  transient  attacks  which  come  on  sooner  or  later  after 
an  abrasion  are  well  known.     They  have  been  wrongly 
called  nervous.     They  are  always  occasioned  by  a  me- , 
chanical  cause,  generally  at   the  moment  the  patient 
awakes.     This  mechanical  cause  is  die  friction  of  the 
eyelid  against  the  eye,  owing  to  the  moisture  which  comes 
during  sleep,  and  the  rubbing  with  the  fingers  by  the  pa- 
tient, who  fancies  that  there  is  a  foreign  body  in  his  eye. 
The  nerves  of  the  epithelium  remain  in  an  unhealty  con- 
dition— ^perhaps  the  regeneration  of  the  epithelium  is  de- 
fective—-despite  the  apparently  normal  appearance  of 
the  eye.     A  slight  traumatism  would  suffice,  then,  to 
provoke  a  bad  attack.     Sometimes,  and  oftener  than 
one  thinks,  it  is  real  keratitis  which  takes  place.    This 
keratitis  always  returns  to  the  bullous  form.     Most  fre- 
quently the  bulla  is  difficult  to  see  directly,  but  can 
always  be  seen  by  withdrawing  the  anterior  surface  of  the 
epithelium  by  means  of  iris  forceps.    The  bulla  is  always 
extensive,  in  some  cases  occupying  more  than  half  the 
corneal  surface.    Bullous  keratitis  is  not  always  allied  to 
a  glaucomatous  condition,  or  to  other  serious  affections 
of  the  eye. 

In  some  cases  there  is  a  symmetrical  eruption  in  the 
other  eye,  even,  although  there  is  absolute  certainty  that 
this  eye  has  not  been  previously  injured. 

2.  The  second  form  was  one  of  slow  progress  accom- 
panied by  very  slight  subjective  symptoms,  and  having 
hardly  any  vascular  injection.  There  is  a  slight  grayish 
infiltration,  difficult  to  see,  having  a  tendency  toward 
serpiginous  increase.  It  spreads  by  slight  projectmg 
nodules,  which  are  more  densely  infiltrated  than  the  rest. 
The  affection  always  remains  superficial.  Neither  the 
deep  layers  of  the  cornea  nor  the  iris  are  ever  invaded. 
The  affection  is  undoubtedly  of  mycotic  origin. 

On  the  1 2th,  Prof.  Meyer  presiding,  Dr.  Eadard,  of 
Paris,  read  an  interesting  paper  on 

THE   TESTING   OF  VISION   OF   RAILWAY    EMPLOYEES. 

Dr.  Liebrecht  read  a  paper  on  the  same  subject,  and 
a  third  was  read  by  Dr.  Fox,  of  Philadelphia,  for  Prof. 
William  Thompson. 

Prof.  Sattler,  of  Erlangen,  read  a  paper  on  our  ac- 
tual standpoint  with  regard  to  the  conception  of  diseases 
of  the  conjunctiva  and  of 

THE   NATURE  AND  THERAPEUTICAL  ACTION  OF  JEQUIRrTY. 

With  regard  to  jequirity,  Professor  Battler's  experience 
was  that  the  infusion  of  this  drug  was  very  beneficial  in 
granular  affections  of  the  conjunctiva.  In  all  cases  he 
found  the  characteristic  bacillus  in  the  infusion  used.  In 
some  cases  lesions  of  the  cornea  were  produced,  espe- 
cially by  frequent  repetitions  of  the  process  in  rapid  suc- 
cession. For  this  reason  he  thought  it  not  safe  to  use 
the  drug  in  cases  where  the  cornea  was  unaffected. 

Dr.  Benson,  of  Dublin,  had  used  jequirity  infusion  in 
upward  of  fifty  cases,  and  had  found  it  very  beneficial  in 
granular  conjunctivitis  and  pannus.  In  some  cases  he 
could  find  no  trace  of  the  bacillus  in  the  infusion  used. 

Dr.  E.  Meyer,  of  Paris,  read  a  paper  on 

THE   ARTIFICIAL   MATURATION   OF   CATARACT. 

The  chief  points  of  his  paper  were  as  follows  :  The 
opacification  of  the  whole  of  the  lens  substance,  which 
alone  admits  of  its  complete  expulsion,  is  a  desideratum 
in  the  normal  extraction  of  cataract.  In  cases  where 
extraction  of  incomplete  senile  cataract  is  compulsory, 
this  artificial  maturation  is  indicated.  The  best  known 
method  of  maturation  is  that  of  massage  of  the  crystal- 
line lens  through  the  cornea  (Fttrster)  after  the  evacua- 
tion of  the  aqueous  humor  from  the  anterior  chamber. 

Iridectomy,  he  said,  was  of  great  importance.  The 
pressure  should  be  made  with  an  instrument  (shown) 
which  made  it  general  all  over  the  cornea,  and  not  local- 
ized. He  showed  a  rabbit  (living)  in  which  he  had  pro- 
duced cataract  by  this  massage  two  days  before,  in  the 
presence  of  several  members  of  the  section.    The  lens 


•       October  4,  1884.] 


THE  MEDICAL  RECORD. 


389 


of  the  rabbit  was  now  quite  opaque  in  the  upper  part, 
and  partially  so  all  ovei;.  There  was  no  marked  inflam- 
mation of  the  rabbit's  eye.  Prqfessor  Meyer  was  not 
prepared  to  state  the  exact  pathological  process  by 
which  this  opacity  was  brought  about. 

Dr.  Mooren,  of  Diisseldorf,  criticized  the  operation  ; 
he  had  lost  one  eye  by  this  method,  and  was  less  san- 
guine of  its  success  than  Dr.  Meyer  appeared  to  be. 

Dr.  Samelsohn,  of  Cologne,  had  tried  it  in  a  number 
of  cases  in  some  of  which  there  were  only  cortical  opaci- 
ties.   Some  of  his  cases  had  succeeded,  some  not. 

Dr.  Abadie,  of  Paris,  objected  to  the  operation  be- 
cause of  the  difficulty  of  inducing  patients  to  submit  to 
so  tedious  a  process. 

Prof.  Gayet,  of  Lyon,  read  a  paper  on  the 

RESULT  OF  great  LOSSES  OF  SUBSTANCE  OF  THE  CORNEA. 

The  opening  of  large  abscesses  and  the  constant  wash- 
ing of  them  constitute  a  mode  of  treatment  more  advan- 
tageous, and  for  which  one  cannot  be  too  grateful  to 
those  who  have  laid  down  the  principle  of  it.  Unfortu- 
nately, if  the  eye  is  permanently  saved,  it  is  not  pro- 
tected from  progressive  staphyloma,  large  adherent  leu- 
comas,  synechia  of  the  iris,  and  cataracts.  Surgery  has 
certainly  preserved  the  organ,  but  for  the  most  part  it 
has  preserved  a  useless  organ,  when  it  is  not  injurious, 
either  through  the  pain  it  causes  or  from  sympathy  which 
it  engenders.  I  think,  with  the  help  of  certain  facts, 
that  it  would  perhaps  be  possible  to  substitute  for  the 
simple  opening  of  the  abscess  a  peripheral  of  the  cornea 
with  a  large  iridectomy. 

Dr.  Boucheron,  of  Paris,  read  a  paper  on 

THE  USE  OF  ATROPINE    AT  THE  COMMENCEMENT  OF   CON- 
VERGENT  SQUINT. 

The  chief  points  of  this  paper  were  as  follows:  At 
the  commencement  of  convergent  strabismus  the  pro- 
longed use  of  atropine  in  both  eyes  appeared  to  be  the 
.  best  means  of  treatment,  because  it  counteracted  the  in- 
stinctive and  excessive  efforts  at  accommodation  in  a 
young  ametropic  child,  in  its  flrst  attempts  at  near  vision. 
The  amount  of  atropine  used  must  be  sufficient  to  cause 
paralysis  of  the  accommodation  and  extreme  dilatation 
of  the  pupil.  Atropine  was  only  efficacious  during  the 
period  in  which  the  strabismus  was  intermittent,  that  is 
to  say,  during  the  time  when  secondaiy  retraction  of  the 
internal  rectus  was  absent.  This  period  was  very  short 
A  favorable  condition  to  the  cure  by  atropine  is  found 
in  the  rapid  growth  of  the  infant,  especially  in  the  devel- 
opment of  the  face^  and  more  particularly  the  enlarge- 
ment of  the  ethmoid  bone,  because  such  development 
brings  about  a  separation  of  the  orbital  axis  and  a 
diminution  in  the  strength  of  the  convergent  muscles. 

The  advantageous  result  of  the  atropine  cure  being 
applied  from  the  commencement  of  convergent  strabis- 
mus is  caused  by  the  [rapid  restoration  of  the  eye  from 
deviation,  thus  often  saving  it  from  becoming  amblyopic. 
When  it  is,  as  we  think,  the  consequence  of  an  arrest  in 
development  of  the  macula  after  birth  and  consecutive 
to  deviation  of  one  of  the  eyes,  electricity  is  often  very 
useful.  The  correcting  glasses  for  ametropia  may  be 
used  at  the  same  time,  or  after  the  atropine  cure,  to 
guard  against  any  relapse.  If  "amblyopic  exanopsia" 
has  been  avoided  by  using  atropine  and  electricity,  the 
bandage  or  the  glasses  are  less  frequently  used.  Tenot- 
omy is  always  the  best  treatment  for  permanent  squint. 

Inconveniences  from  atropine — special  intolerance^ 
conjunctivitis — are  very  rare  with  young  children ;  they 
are  avoided  by  the  use  of  the  first  remedies,  and  by 
<^|^^uiging  the  mydriatics  when  ill-supported.  The  myo- 
tics which  contract  the  muscles  of  accommodation, 
in  suppressing  also  the  instinctive  and  exaggerated  ef- 
forts of  the  accommodation  equally  produced,  as  he  had 
abready  pointed  out,  very  favorable  results  in  the  early 
squint,  but  the  myotics  appeared  to  him  less  active  than 
the  mydriatics. 


Mr.  Yuler,  of  London,  thought  there  was  niuch  in  the 
paper  demanding  the  consideration  of  ophthalmic  sur*- 
geons.  With  regard  to  the  second  point  in  Dr.  Bou- 
cheron*s  paper,  he  had  tried  atropine  in  many  cases  of 
convergence,  and  while  it  had  often  succeeded  in  curing 
the  intermitted  cases,  he  had  never  once  found  it  sufficient 
to  remove  a  squint  which  had  become  permanent.  He 
always  corrected  the  ametropia  at  the  time  and  before 
discontinuing  the  use  of  the  atropine. 

Dr.  E.  Hansen  Grut  read  a  paper  on 

LATENT   STRABISMUS,    KSPfiClALLY    LATENT    DIVERGENCE, 

Latent  divergence  is  not  far^sis^  neither  is  it  muscular 
weakness.  With  just  as  littk  reason  can  it  be  attributed 
to  increased  power  in  the  external  recti.  It  depends  on 
a  defective  impulse  to  convergence.  The  expression 
"  loss  of  muscular  power  of  internal  recti "  is  erroneous, 
and  does  not  express  the  true  stite  of  the  case.  It  is  the 
relation  between  convergence  and  accommodation  which 
chiefly  determines  the  latent  condition  of  the  covered  eye. 
In  order  to  estimate  the  latent  position  two  things  are 
absolutely  necessary:  i,  Accurate  accommodation  for 
the  point  of  fixation ;  2,  an  absolute  condition  of  rest  of 
the  eye  in  looking  at  the  distance. 

Fusion  is  possible  in  spite  of  latent  divergence.  Usu- 
ally correct  fixation  can  be  maintained,  so  that  generally, 
even  with  very  pronounced  latent  divergence,  there  is 
no  convergence  asthenopia  if  the  power  of  fusion  is  good. 
A  defective  power  of  fusion  renders  difficult  or  prevents 
maintenance  of  exact  position.  In  this  case  there  is  no 
efifort  which  would  lead  to  muscular  fatigue,  but  diplopia. 
If  there  is  good  power  of  fusion,  but  great  divergence 
in  condition  of  absolute  rest,  an  effort  to  converge  is 
made,  but  by  no  means  so  often  as  is  usually  thoughts 
Clinical  experience  alone  can  determine  how  often  and 
when  muscular  asthenopia  is  present.  The  frequency  of 
muscular  asthenopia  has  become  very  great,  and  our 
means  of  diagnosing  its  presence  are  somewhat  defective. 
In  the  first  place  the  symptoms  of  muscular  asthenopia 
are  extremely  variable,  and  not  nearly  as  easy  to  classify 
as  those  of  accommodative  asthenopia.  Numberless 
cases  of  nervous  asthenopia  are  erroneously  diagnosed  as 
muscular.  The  relation  between  the  available  power  of 
adduction  and  the  degree  of  latent  divergence  is  not  suffi- 
cient to  indicate  whether  muscular  asthenopia  is  present  or 
not.  The  same  is  true  of  exclusion  of  one  eye  during  work 
and  of  the  employment  of  prisms.  The  slight  degrees  of 
latent  divergence  (under  16'')  cause  muscular  asthenopia, 
almost  without  exception.  The  most  delicate  tests  for 
measuring  accurately  the  degrte  of  the  latent  divergence 
are  uncertain,  and  are  moreover  superfluous. 

An  operation  is  only  justifiable  when  there  is  more 
latent  divergence  in  condition  of  absolute  rest  The 
operation  is,  therefore,  performed  rather  on  account  of 
latent  absolute  squint  than  for  insufficiency.  It  is  in- 
jurious to  produce  by  this  operation  an  absolute  condition 
of  convergence  in  the  condition  of  rest,  even  though 
the  power  of  abduction  may  still  be  sufficient  to  over- 
come the  homonymous  diplopia  at  the  time, 

Mr.  Yuler,  of  London^  gave  demons tration^  in  the 
Section  of  Ophthalmology  of 

(l)    frost's   ARTIFICIAL   EYE^ 

This  is  an  excellent  'instrument  for  teachmg  purposes* 
It  is  provided  with  two  movable  retina^^  one  of  glass  and 
the  other  painted  so  as  to  represent  the  normal  fundus. 
By  means  of  a  delicate  screw  the  eye  can  be  shortened  and 
lengthened  so  as  to  represttnt  hypermeiropia,  emmetropia, 
and  myopia,  respectively,  and  by  then  adding  a  cylindri- 
cal glass  to  the  front  of  this  it  becomes  astigmatic.  All 
the  characterisdc  signs  of  einmetropia  and  ametropia  can 
be  clearly  taught  by  this  instrument. 

(2)    M*HARDV'S    PERIMETER.! 

This  is  a  self-registering  instrument  of  excellent  work- 
manship.    It  is  self-regisiering  and  combines  the  proper- 


1 


r 


390 


THE  ^MEDICAL  RECORD. 


[October  4,  1884, 


ties  of  Forster^s  instniment  It  is  a  decided  improvement 
upoQ  the  perimeter  shown  at  the  London  Congress  by 
Stevens, 

Both  Mc Hardy's  perimeter  and  Frost's  artificial  eye 
can  be  obtained  o(  Picard  &  Curry,  London. 

Dr.  Noyes,  of  New  York,  read  a  paper  on 


ASTHENOPIA     FROM 


INSUFFICIENCY    OF  ^THE 
RECTI   MUSCLES. 


EXTERNAL 


He  Spoke  of  the  small  degree  of  attention  which  had 
been  given  to  this  topic  in  text-books  and  in  journals. 
While  the  varying  degrees  of  accommodation  appropriate 
to  given  amounts  of  convergence  had  been  carefully 
studied  by  Donders  and  others,  and  that  too  in  various 
states  of  refraction,  there  had  been  very  little  study  of 
the  degrees  of  muscular  effort  which  belong  to  spe.cial 
amounts  of  accommodation.  The  latest  and  best  con- 
tribution IS  by  Bissinger  under  the  auspices  of  Nagel, 
but  this  is  brief  and  he  confessedly  leaves  much  to  be 
done.  In  the  study  of  asthenopia  Dr.  Noyes  attempts 
to  find  the  real  conditions  of  muscular  power,  both  with 
and  without  accommodation.  He  tests  the  adduction 
and  abduction  bath  for  the  working  distance  and  for  six 
metres.  He  does  this  in  both  regions  with  the  glasses  which 
the  patient  may  require.  He  employs  Graefe's  equi- 
librium test  in  both  regions,  but  he  finds  it  of  very  un- 
certain value.  Inasmuch  as  all  the  cases  which  he 
studied  were  asthenopic  and  therefore  were  in  a  patho- 
logical condition,  he  found  that  the  relations  between 
Accommodation  and  convergence  had  been  in  many  in- 
stances entirely  disrupted.  So  frequently  was  this  the  case 
that  he  adopied  the  plan  of  resorting  to  atropine  in  very 
many  cases,  and  in  all  those  which  were  attended  with  se- 
vere pain.  He  found  it  necessary  to  do  this  to  bring  to 
view  the  real  ability  of  the  muscles  in  adduction  and  in  ab- 
duction, and  he  was  also  obliged  to  wait  in  many  instances 
for  the  mydriasis  to  subside  before  the  ultimate  and  true 
status  could  be  ascertained.  It  is  rare  that  one  exam- 
ination will  suffice.  By  a  process  both  of  analysis  and 
of  synthesis,  that  is  of  examining  the  functions  separately 
and  in  combination  with  each  other,  he  found  that  he 
could  With  greater  certainty  arrive  at  the  truth.  The 
mydriatic  not  only  aided  in  making  a  diagnosis  but  was 
also  a  therapeutic  measure. 

Dr,  Noyes  had  brought  together  83  cases  of  asthen- 
opia from  insufficiency  of  the  external  recti.  The  largest 
number  (viz. ,  30)  were  among  hypermetropes,  while  em- 
metropes  {viz.,  20)  came  next  in  frequency,  then  cases  of 
astigmatism  {viz.,  i8),  and  lastly,  15  were  myopes.  A 
number  of  cases  included  in  the  report  were  found  to 
consist  essentially  of  spasm  of  accommodation,  but  this 
was  associated  with  and  in  reality  caused  by  debility  of 
the  externi.  In  all  asthenopic  cases  Dr.  Noyes  looks 
for  spasm  of  accommodation,  and  if  it  exist  in  notable 
degree  this  becomes  an  absolute  indication  for  atropia 
to  full  paralysis  of  A. 

What  degree  of  deficient  abduction,  or  what  dispro- 
portion between  abduction  and  adduction  shall  be  ac- 
counted abnormal  cannot  be  dogmatically  asserted. 
The  existence  of  pain  in  use  of  the  eyes,  not  relieved 
by  suitable  glasses  or  by  atropia,  or  by  attending  to  other 
well-known  concomitant  conditions,  was  sufficient  reason 
to  resort  to  the  local  treatment  which  had  been  most  of- 
ten successful,  viz.,  the  employment  of  prisms  with  the 
bases  outward,  amounting  as  a  total  to  three  or  six  de- 
grees, to  be  worn  in  most  cases  all  the  time,  both  for 
die  distance  ami  for  the  near. 

Dr,  Noyes  clearly  discriminated  between  the  asthen- 
opic cases  in  which  the  muscular  trouble  was  entirely  re- 
flex and  the  product  of  remote  disease,  as  of  the  uterus, 
lungb,  etc.,  and  those  in  which  there  was  an  idiopathic 
weakness  of  the  tnuscles.  In  the  former  cases  local 
measures  were  of  minor  value,  while  in  the  latter  they 
were  of  notable  advantage.  There  are  also  mixed  cases 
which  are  both  retiex  and  idiopathic.     In  only  five  cases 


Was  tenotomy  performed — in  four  with  entire  success,  in 
one  without  success. 

A  point  to  which  Dr.  Noyes  called  attention  was  the 
latent  character  of  insufficiency  of  the  extemi,  and  espe- 
cially to  the  fact  that  in  some  of  the  cases  which  proved 
by  experience  to  be  insufficiency  of  the  extemi,  the  evi- 
dence furnished  by  Graefe's  equilibrium  test  pointed  to 
insufficiency  of  the  interni.  He  did  not  refer  to  myopic 
cases,  but  to  other  forms  of  ametropia  and  to  emme- 
tropia.  In  these  relief  was  secured  by  wearing  con- 
stantly, and  both  for  near  and  far  vision,  adductive 
prisms,  while  in  a  very  few  cases  abductive  prisms  were 
used  for  the  near  vision  and  adductive  prisms  for  dis* 
tance.  These  cases  were  noticed  by  Graefe  and  by 
many  others  since  his  time.  They  have  divergence  for  the 
working  distance,  and  convergence  or  perhaps  equilib- 
rium for  the  distance  of  six  metres  when  examined  by  the 
equilibrium  test.  Some  of  them  are  truly  cases  of  latent 
or  manifest  insufficiency  of  the  extemi,  and  if  treated  as 
such  they  recover.  Dr.  Noyes  desired  to  call  attention 
to  this  mode  of  regarding  them,  which  had  proved  of 
great  importance  in  his  own  experience,  and  which  he 
believed  would  be  found  to  be  the  solution  of  some  dif- 
ficult and  not  infrequent  cases. 

Of  the  83  cases  the  results  of  treatment  were  known 
in  65. 


Patients  having — 

Cured. 

Relieved. 

1 
Not  relieved.  |      Totals. 

Hypermetropia,  a8  cases . . . 
Enunetropia,       14     *'     ... 
Astigmaitsin,       15     *'     ... 
Myopia,                 8     "     ... 

percent 
"    =  39 
3   =  a«  5 
5   =  33-3 
3   =  37-5 

percent. 

9   ==  60 
5   =  6a.5 

percent. 
5   =B  >8 
2    =  18   • 
1    =     6.6 
0    =s     0 

percent 
38  =  100 

14  =  100 

15  =  100 

8  =  100 

Total,    65  cases... 

aa    =  34 

35   =  54 

8   =  la         6s  =  100 

(SiOVXtSTpfm&sviCt, 


OUR  LONDON   LETTER. 

(From  our  Special  Correspondent.) 
THE  MEDICAL  ACT  AND  THE  LICENSING   BODIES — LONDON 
AND    EDINBURGH  UNIVERSITY  EXAMINATIONS — ^THE  SO- 
CIETIES— HOSPITAL    SATURDAY — DECREASE    OF    SMALL- 
POX— THE  INVENTOR  OF  CHLORODYNE. 

London,  September  13,  1884. 

The  Medical  act  having  been  withdrawn  by  the  Govern- 
ment,  all  the  examining  bodies  are  free  to  pursue  their 
career  unchecked  for  at  least  another  year — probably 
for  several  years.  These  comprise  (within  the  United 
Kingdom)  eleven  universities  and  nine  corporations,  but 
as  for  many  years  past  one  university  (St.  Andrews)  has 
almost  ceased  to  give  degrees  except  to  those  already 
qualified  and  on  the  register,  and  the  Edinburgh  Colleges 
of  Physicians  and  Surgeons  have  lately  agreed  to  only 
give  their  diplomas  jointly  in  future,  the  portals  by  which 
^he  profession  may  be  entered  now  only  number  eighteen. 
These  are  more  than  enough  for  a  profession  of  only 
twenty-five  thousand  members.  The  mischief  consists 
more  in  the  inequality  of  the  tests  imposed  by  these 
various  bodies.  Even  the  universities  vary  greatly.  An 
M.D.  Edin.  is  very  different  from  an  M.D.  Lond.  At 
Edinburgh,  at  all  except  the  final  examination  for  the 
M.B.  degree,  if  a  candidate  fail  only  in  one  subject  he 
is  allowed  to  go  up  again  in  that  subject  alone  in  a  few 
months'  time.  One  or  two  failures  in  single  subjects  do 
not,  therefore,  necessarily  prolong  his  curriculum.  I  am 
informed  that  even  at  the  final  examination,  should  a 
candidate  do  badly  at  his  clinical  he  is  allowed  to  have 
a  second  chance  before  being  finally  rejected.  If  then 
unsuccessful  he  has  to  wait  twelve  months  before  going 
up  again. 

At  the  examinations  for  the  London  University  M.B. 
degree,  failure  in  only  one  subject  is  fatal  The  whole 
examination  has  to  be  passed  over  again,  including  those 
subjects  in  which  the  candidate  was  previously  success- 
ful.    With  the  exception  of  that  for  matriculation,  the 


October  4,  1884.] 


THE   MEDICAL  RECORD. 


391 


examinations  are  only  held  once  a  year,  so  each  failure 
involves  a  year's  delay. 

Without  discussing  the  question  of  whether  the  London 
University  examinations  are  harder  in  themselves  than 
the  Edinburgh  ones,  these  differences  obviously  render 
the  Edinburgh  degree  easier  of  acquirement.  Some 
choice  also  is  allowed  at  the  earlier  examinations  there 
as  to  what  subjects  to  be  examined  in  at  once.  At  the 
London  the  only  option  now  allowed  is  in  physiology, 
that  lately  offered  at  the  preliminary  scientific  examina- 
tion being  now  rescinded.  I  think,  though,  on  the  whole 
there  cannot  be  much  doubt  that  the  "  London  "  is  more 
exacting  than  its  Northern  sister.  With  all  the  advantages 
offered  in  our  London  schools,  the  proportion  of  London 
students  who  graduate  at  it  is  very  small. 

The  medical  societies  will  soon  begin  their  meetings 
again.  A  practitioner  who  attends  several  societies  regu- 
larly finds  a  distinct  gap  made  in  his  winter  evenings. 
Four  of  them,  viz.,  the  Medico-Chirurgical,  Clinical, 
Pathological,  and  Obstetrical,  meet  in  the  same  rooms  on 
different  evenings.  It  has  been  proposed  to  amalgamate 
these,  and  perhaps  the  Medical  Society  also,  under  the  title 
of  the  "  Academy  of  Medicine,"  with  of  course  different 
sections.  This  arrangement  wDuId  have  many  conven- 
iences, but  although  it  has  several  times  been  proposed 
nothing  has  come  of  it  as  yet.  One  practical  difficulty 
consists  in  the  varying  rates  of  subscription  of  the  vari- 
ous societies.  Another  would  be  found  in  arranging  the 
division  of  the  property  held  by  them.  The  Medico- 
Chirurgical  possesses  what  is  considered  to  be  the  best 
medical  library  in  London,  and  its  Fellows  are  allowed  to 
take  the  books  home  to  read.  The  Obstetrical  Society 
also  owns  a  very  good  library.  The  Dublin  societies 
have,  however,  united  to  form  the  "  Academy  of  Medi- 
cine in  Ireland,"  with  four  sections  and  two  sub-sections, 
so  perhaps  the  London  societies  may  yet  see  their  way 
to  follow  suit. 

Hospital  Saturday  has  been  so  unsuccessful  this  year 
that  it  is  proposed  to  have  a  second  one  this  day  fortnight. 
At  its  best  it  has  never  been  as  successful  as  the  Hos- 
pital Sunday  Fund.  Last  year  the  "  Sunday  "  brought  in 
more  than  three  times  the  amount  of  the  "Saturday"  fund. 
Small-pox  is  rapidly  decreasing.  Last  week  only  twelve 
deaths  from  it  occurred  in  London. 

Dr.  Collis  Browne,  the  so-called  inventor  of  chloro- 
djTie,  has  just  died.  Chlorodyne  is  perhaps  the  only 
patent  medicine  and  secret  remedy  which  has  been 
kgely  employed  by  medical  men.  The  makers  con- 
tended that  it  contained  a  certain  alkaloid  which  gave  it 
valuable  properties.  They  declared  that  this  could  not 
ie  discovered  by  analysis.  This  proved  to  be  so  far 
correct  that  many  people  were  inclined  to  regard  the 
"alkaloid  "  as  a  myth.  Several  lawsuits  have  been  waged 
over  chlorodyne.  The  final  result  was  to  leave  the 
iriginal  inventor.  Dr.  Browne,  in  undisturbed  possession 
bf  his  rights.  He  derived  a  large  income  from  the  sale 
of  the  preparation. 

CENTRAL  EUROPE  IN  A  CHOLERA  SUMMER 
-THE  CLEANLINESS  OF  PARIS  AND  LON- 
DON— THIRD  INTERNATIONAL  CONGRESS 
OF  OTOLOGY,  IN  BASEL. 

To  THB  EdITOK  or  THB  MBDICAL  RBC30KD. 

Sir:  I  would  not  advise  even  a  medical  man,  who 
desires  a  vacation  in  Europe,' unless  he  is  specially  in- 
terested in  the  germ  theory,  to  choose  a  summer  in  which 
Asiatic  cholera  is  epidemic  in  a  few  places,  and  is  about 
to  become  epidemic  in  a  great  many  more.  But,  to  the 
passengers  landing  at  Southampton  on  June  26th,  the 
announcement  that  cholera  had  broken  out  in  Toulon, 
and  that  it  would  undoubtedly  spread  over  France  and 
throughout  Europe,  was  like  thunder  from  a  clear  sky. 
^tany  a  prophet  has  lost  what  reputation  he  may  have 
«ad  by  predictions  as  to  how  and  where  the  cholera  would 
extend.  The  July  ftte  was  to  bring  it  to  Paris.  The  fftte 
,  was  held,  but  no  cholera  came.     Refugees  from  Toulon 


and  Marseilles  came  to  Paris  by  the  hundred  ;  some  of 
them  to  the  very  hotel  from  which  this  letter  is  written. 
No  quarantine  was  established.  People  were  not  even 
disinfected,  but  Paris  has  been  kepi  strictly  clean,  and  if 
the  cholera  has  reached  it  at  all,  it  has  only  been  in  a  few 
sporadic  cases,  as  yet  scarcely  worthy  of  specific  atten- 
tion. On  the  other  hand,  poor  Italy  has  rigidly  main- 
tained a  quarantine  extending  even  to  the  peaks  of 
almost  inaccessible  frontier  moun  tain  tops,  and  maintained 
it  actually  at  the  point  of  the  bayonet.  She  neglected, 
however,  to  clean  Spezzia  and  Naples,  and,  as  we  all 
know,  she  is  suffering  from  an  epidemic  as  ruthless  as 
that  which  depopulated  and  impoverished  the  cities  and 
villages  of  Southern  France.  The  condition  of  Naples, 
at  the  time  of  the  late  outbreak,  was  the  same  as  that 
which  has  given  it  a  pre-eminence  among  filthy  cities. 
There,  was  not  enough  water  for  personal  or  ptiblic 
cleanliness.  Cesspools  existed  in  nearly  all  the  houses 
in  the  poorer  parts  of  the  city.  Their  solid  contents 
were  kept  for  months,  whDe  the  fluid  oozed  away  in 
rather  small  channels.  Their  zeal  in  this  direction  was 
occasioned  by  a  desire  to  enrich  their  vine  and  olive 
yards.  A  great  storm,  occurring  just  before  the  outbreak, 
caused  many  of  the  outlets  of  these  cesspools  to  over- 
flow, with  effects  that  it  does  not  require  a  medical  rnind 
to  imagine.  To  return  to  the  prophets  for  a  moment. 
It  is  said  that  an  English  physician  got  a  guinea  early  in 
the  season  for  advising  an  American  lady,  who  had  come 
to  Europe  for  a  prolonged  stay,  to  sail  for  home  in  the 
first  steamer,  because,  as  he  believed,  the  cholera  would 
soon  be  in  England,  and  then  the  steamers  to  America 
would  cease  running.  As  a  matter  of  fact,  traveling  in 
Central  Europe  this  summer,  barring  the  very  hot 
weather,  has  been  pleasanter  than  usual. 

It  is  true  those  who  trust  to  the  opinions  and  fears 
of  the  average  public  must  have  had  many  misgivings* 
We  were  warned  not  to  go  to  Vienna,  because  the  chol- 
era was  just  about  to  break  out  there.  As  you  know, 
there  has  not  been  a  single  case  in  that  city.  Then, 
again,  we  were  told  that  Switzerland  would  be  packed 
frill  of  people  and  very  unhealthy,  but  Switzerland  was 
not  full,  and  was  never  healthier.  Poor  Cweneva  was  al- 
most bereft  of  American  and  English  visitors  on  account 
of  the  repeated  statements  that  the  cholera  had  actually 
broken  out  there.  I  think  Americans,  as  a  rule — those 
who  did  not  turn  back  to  enjoy  the  earthquake — went  to 
Scandinavia,  Ireland,  Scotland,  and  England.  Occa- 
sionally one,  not  able  to  resist  the  blandishments  of  Paris, 
stole  over  from  dirty  London  to  that  most  cleanly  city. 
We,  in  Central  Europe,  have  had  exceedingly  good 
rooms,  attendance,  and  very  civil  landlords,  but  a  very 
hot  summer.  A  few  travellers  have  been  disinfected  at 
Geneva,  but  it  seems  to  have  been  rather  a  source  of 
amusement  than  of  actual  annoyance.  I  think  it  re- 
mains to  be  proven  that  quarantine  or  disinfection  are 
of  the  slightest  service.  If  cholera  be  a  contagious  dis- 
ease, then  it  is  very  singular  that  the  most  of  France,  all 
of  Germany,  Austria,  and  Switzerland  have  thus  far  es- 
caped the  epidemic,  while  fugitives  from  Toulon  and 
Marseilles  have  been  running  with  tlieir  bag  and  baggage 
all  over  these  countries  without  let  or  hindrance,  I 
suppose  the  ravages  of  the  disease  at  Naples  can  hardly 
be  exaggerated,  but  if  our  newspapers  would  cease 
to  put  panic-striking  head-lines  over  the  paragraphs  in 
regard  to  the  spread  of  the  cholera,  and  reserve  their 
rhetoric  for  appeals  for  personal  and  public  cleanliness, 
much  could  be  done  to  arrest  the  progress  of  an  epi- 
demic, the  cause  of  which  we  know  to  be  chiefly  founded 
in  dirt.  It  is  possible  that,  despite  the  Berlin  confer* 
ence  and  its  opinions,  we  shall  all  yet  believe  that  cholera 
Asiatica,  cholera  nostras,  and  cholera  morbus  are  one 
and  the  same. 

The  man  in  Tennessee  about  whom  I  read  in  a  New 
York  paper,  and  the  one  in  Ireland,  may  actually  have  had 
cholera  like  that  of  Naples.  The  results  of  British  cleanli- 
ness in  India  seem  to  indicate  that  cholera  may  often  be 


392 


THE  MEDICAL  RECORD. 


[October  4,  1884, 


expected  where  great  heat,  public  and  personal  filth  exist 
in  the  proper  combinations.  As  has  been  already  inti- 
mated, this  letter  is  written  from  Paris.  I  have  never 
had  a  proper  idea  of  how  a  great  city  may  be  kept  clean 
until  I  saw  Paris  as  it  is  this  summer.  Clear  water  ac- 
tually flows  through  the  gutters  and  over  the  streets  two 
or  three  times  a  day.  The  poor  quarters  are  as  clean  as 
those  in  which  the  rich  live.  London  bears  no  compar- 
ison to  the  French  capital  in  point  of  cleanliness.  In 
fact  London  seems  to  me,  in  this  latter  part  of  September, 
by  no  means  a  clean  city.  Cleaner  than  New  York  it 
certainly  is,  and  I  read  in  the  English  papers  that  they 
are  cleaning  up  everywhere.  One  of  her  eminent  sani- 
tary authorities  states  that  cholera  in  England  always 
saves  more  lives  than  it  takes,  since  it  lessens  the  mor- 
tality from  typhoid  fever  for  a  year  ;  the  cleaning  being 
too  late  for  one  purpose,  but  in  time  for  the  oth^r.  I 
hear  great  things  of  the  cleansing  which  has  been  under- 
taken in  New  York  this  summer.  It  is  to  be  devoutly 
hoped  that  it  is  all  true.  With  the  standard  of  cleanli- 
ness that  has  hitherto  existed  among  our  rulers,  and  with 
our  bad  pavements  and  our  scarcity  of  water,  I  doubt 
very  much  if  New  York  is  yet  clean.  Our  passengers 
will  be  convinced  if,  when  landing  from  the  ocean  steamer, 
we  are  not  regaled  with  the  usual  sights  and  smells  of  Canal 
and  Christopher  Streets,  and  Seventh  Avenue.  Perhaps 
the  medical  profession  of  New  York  could  not  do  a  better 
work  this  winter  than  in  preparing  for  the  cholera  of  next 
summer  by  organizing  a  street  repairing  and  cleansing  so- 
ciety. Whatever  other  lessons  this  season  of  cholera  has 
conveyed,  this  one  stands  out  pre-eminently,  that  in  clean- 
liness, >  personal,  household,  and  municipal,  are  to  be 
found  the  only  preventive  means,  while  quarantines  and 
disinfections  are  but  delusions  and  snares. 

Many  of  the  readers  of  The  Record  may  have  for- 
gotten that  the  first  International  Congress  of  Otology 
was  held  in  New  York  in  1876.  It  was  very  sparsely  at- 
tended by  Europeans.  Indeed,  I  believe  but  one  paper 
was  read  for  a  foreigner.  The  Congress  was  held  in  the 
same  year  with  the  International  Medical  Congress  in 
Philadelphia  and  the  International  Congress  of  Oph- 
thalmology in  New  York.  There  was  a  volume  of  Trans- 
actions published,  however,  and  a  second  Congress  was 
held  in  Milan  in  1880.  The  third  has  just  taken  place 
in  Basel,  from  the  ist  to  the  4th  of  September.  Basel  has 
a  small  university,  but  one  of  renown.  Vesalius  taught 
anatomy  there,  and  it  has  furnished  several  great  teachers 
to  other  universities.  Through  the  efforts  of  Professor 
Burckardt-Merian  and  Professor  Politzer,  Drs.  Lowen- 
berg,  M6ni6re,  and  others  of  the  Committee  of  Arrange- 
ments, the  Congress  was  a  success  in  numbers  and  in 
the  character  of  the  papers  read.  More  than  eighty 
names  were  inscribed  on  the  roll,  among  which  were 
Moos,  Bezold,  Pritchard,  Politzer,  Delatouche,  M€ni6re, 
Gelle,  Lowenberg,  Guye,  CoUadon,  Hartmann,  Kuhn, 
Sapolini,  and  Valentin. 

The  Governments  of  Switzerland  and  of  Basel  were  very 
courteous  and  hospitable.  The  social  entertainments — 
public  breakfasts  and  dinners — were  of  a  charming  kind. 
The  speeches  of  the  representatives  of  the  municipal  and 
State  authorities  were  even  eloquent.  In  fact,  it  seemed 
to  me  that  the  manner  of  speaking  of  our  Continental 
brethren,  both  in  the  Congress  and  at  the  social  enter- 
tainments, was  singularly  happy.  Some  of  the  speakers 
read  their  papers  while  sitting,  after  the  manner  of  Ger- 
man professors  in  the  lecture-room.  This  seemed  to  me 
to  contribute  materially  to  the  ease  of  the  delegate  read- 
ing a  paper.  The  discussions  were  lively  in  the  extreme, 
as  well  as  polyglot.  French  was  the  leading  language, 
since  no  Frenchman  ever  appears  to  understand  or  speak 
any  language  but  his  own.  Burckardt-Merian,  Politzer, 
and  Moos  gave  some  very  fine  anatomical  and  patho- 
logical demonstrations.  The  papers  read  in  French 
were  epitomized  in  English  and  German  by  Guye  and 
Lowenberg,  who  were  the  volunteer  interpreters  for  the 
Congress.     At  some  points  the  bounds  at  the  dispersion 


from  the  tower  of  Babel  were  possibly  reproduced.  1 
am  sure  many  of  the  readers  of  The  Record  will  be  in- 
terested  in  the  volume  of  Transactions. 

The  next  session  of  the  Congress  is  to  be  held  in  1888 
in  Brussels.  A  telegram  was  read  from  the  mayor  of 
that  city  welcoming  the  meeting  in  advance.  A  propo. 
sition  to  meet  in  Washington,  as  a  part  of  the  Interna^ 
tional  Medical  Congress,  fpund  no  favor,  otology  being 
considered  to  be  a  plant  which  requires  a  whole  garden, 
and  not  a  mere  plot,  to  itself.    * 

Paris,  September  xa,  1884.  ^'  B-  St.  JoHN  RoOSA. 

«'  ON  THE   ARREST   OF   TUBAL   PREGNANCY 
BY  GALVANISM." 

To  THB  Editor  of  Thb  Mbdical  Rscoxd. 

Sir  :  In  reading  Dr.  Mund^'s  interesting  case,  in  the  last 
issue  of  The  Record,  entitled  "  A  Successful  Case  of 
Arrest  of  Tubal  Pregnancy  by  Galvanism,"  I  noted  both 
a  point  for  discussion  and  a  mistake  to  correct.  I  ani 
all  the  more  ready  to  avail  myself  of  any  opportunity  to 
extend  the  consideration  of  this  subject  because  it  is  an 
accident  so  comparatively  infrequent  that  it  is  only  occa- 
sionally that  the  immense  value  of  electricity  in  saving  life 
in  this  condition  is  brought  to  the  attention  of  the  profession. 

Considering  the  number  of  successful  cases  that  have 
been  reported,  it  is  indeed  surprising  that  one  meets  with 
so  many  physicians  who  have  either  never  heard,  or  who 
have  forgotten  the  fact,  that  electricity  offers  a  safe  and 
speedy  relief  from  this  dreaded  abnormality  of  pregnane}'. 

Dr.  Mund6  raises  the  question  as  to  the  form  of  cur- 
rent most  suitable  in  these  cases,  preferring  faradism, 
and  basing  his  preference  on  the  satisfactory  use  of  it  in 
several  cases  by  others,  and  on  the  fact  that  in  his  own 
case  prolonged  and  alarming  prostration  followed  the  use 
of  galvanism. 

If  these  cases  were  recurring  with  great  frequency,  ex- 
perience would  soon  decide  whidi  was  the  surer  and 
safer  method,  but  as  they  are  relatively  so  infrequent, 
physical  and  physiological  laws  must  partially  guide  us. 
We  know  that  galvanism  is  a  far  more  potent  agent  than 
faradism  in  its  relation  to  living  tissue,  and  more  de- 
structive to  life,  and  so  has  an  advantage  over  the  far- 
adic  current.  As  to  the  effects  of  the  application  on 
the  mother,  I  am  persuaded  that  they  never  need  be 
harmful,  or  especially  painful,  no  matter  which  forai  of 
current  is  used. 

In  his  own  case,  Dr.  Mund6  made  use  of  twenty-four 
cells,  giving  shocks  that  were  "quite  painful,"  through  a 
stance  of  ten  minutes.  He  says  :  ''  I  did  not  think  the 
current  too  strong,  for  I  remembered  that  in  one  of  the 
successful  cases  reported  (McBumey's),  thirty-six  cells 
had  been  used."  The  correction  that  I  wish  to  make  is 
that,  in  the  case  to  which  reference  is  made,  but  twenty- 
three  cells  were  used. 

In  six  other  cases  where  I  successfully  used  electricity 
(all  of  which  were  reported  in  this  journal),  and  whidi  ^ 
went  to  make  up  the  eleven  cases  collected  by  Gar- 
rigues,  to  which  Dr.  Mund6  refers,  the  current  strength 
was  much  less.     In  two  cases  onl^  twelve  cells  were 
used,  and  in  none  of  them  did  the  slightest  ill  effects  en-  [ 
sue  ;  all  of  which  goes  to  show  that  a  much  weaker  cur-  ; 
rent  of  galvanism  will,  in  all  probability,  prove  effective 
than  was  at  hrst  supposed. 

My  experience  leads  me  to  believe  that  one-half  the   ' 
number  of  cells  used  by  Dr.  Mund6,  and  with  an  appli-  I 
cation  one-half  as  long,  would  have  been  sufficient.    His 
statement  that  thirty-six  cells  were  used  in  McBumc/s 
case  was  due,  I  suppose,  to  the  fact  that  in  the  report  it 
was  stated  that  my  thirty-six-cell  battery  was  brought 

It  is  readily  seen  that  it  must  be  of  vital  importance  to 
use  the  minimum  of  current  strength  necessary  to  destroy 
the  life  of  the  foetus,  not  so  much  perhaps  on  account  of 
the  possibility,  in  rare  instances,  of  its  prostrating  the 
patient,  but  because  the  stronger  the  current  the  greater 
the  possibility  of  rupturing  the  already  distended  tube. 

Scptaabcr27,.i884.  A.  D.  RoCKWKLL,  M.D. 


The   Medical   Record 

A   Weekly  yournal-  of  Medicine  and  Surgery 


Vol.  26,  No.  15 


New  York,  October  ii,  1884 


Whole  No.  727 


dhrifliiml  %xXit\ts. 


CONTRIBUTIONS  TO 
THE  ANATOMY   OF  THE   LEMNISCUS. 

W^iTH  Remarks  on  Centripetal  Conducting  Tracts 
IN  THE  Brain. 
By  E.  C.  SPITZKA,  M.D., 

rtOraSSOR  of  NSURO-ANATOMY  AHD  physiology  IH  the  MBW  YORK  POST-GKAD- 
UATB  MBDICAL  SCHOOL, 


I. — Introduction. 
The  attention  of  those  who  are  interested  in  determin- 
ing the  location  of  special  functional  nerve-tracts  in  the 
brain  and  spinal  cord  has  been  more  particularly  directed 
to  the  one  which  mediates  the  conveyance  of  voluntary 
impulses  from  the  supreme  centres  in  the  cerebral  cortex 
to  the  deputy  centres  or  outposts  in  the  anterior  cornua 
of  the  spinal  cord,  and  their  analogues  the  nuclei  of  cer- 
tain cranial  nerves.  Aside  from  this,  only  the  internal 
capsule,  empirically  discovered  to  contain  a  sensorial 
tract  in  the  posterior  part  of  its  posterior  division,'  and 
the  diflfcrentiated  tracts  in  the  spinal  cord  have  received 
much  attention.  Among  the  reasons  which  account  for 
this  favoring,  thfe  greater  frequency  of  disease  of  these 
parts  as  compared  with  others,  their  easy  topographical 
demarcation,  and  systemic  clearness,  are  the  chief. 

It  is  evident,  however,  to  those  who  look  beyond  the 
popular  aspect  of  cerebral  localization,  that  what  was 
until  quite  recently  a  terra  incognita  to  most  cerebral 
pathologists — the  brain  axis — contains  within  its  labyrin- 
thine maze  the  solution  of  much  that  is  enigmatical  in 
the  cerebral  mechanism.  Here  are  found,  besides  the 
important  cranial  nerve  nuclei,  and  the  tracts  which  bind 
these  into  co-ordinated  reflex  or  automatic  associate 
action,  the  great  projecting  fibre  masses,  which  Meynert 
first  attempted  to  systematize.  Here  are  the  channels 
for  the  transniission  of  special  qualities  of  sensation,  and 
of  those  obscure  influences  which  determine  co-ordination. 
The  tracts  which  are  more  or  less  fused  into  the  bifid 
cylinder  of  the  cord  attain  greater  distinctness,  and  sep- 
arate more  widely,  as  they  pass  through  the  oblongata 
and  pons,  in  order  to  reach  their  mutually  remote  destina- 
tions. Many  of  them  are  inaccessible  to  the  experi- 
menter, and  so  rarely  the  site  of  limited  (focal)  disease, 
that  it  is  improbable  that  their  function  will  ever  become 


.  y  **  »urpn»me  to  find  how  uncertain,  not  general  medical  writers,  but  spe- 
tthsts,  who  have  furnished  accounts  of  the  cerebral  architecture,  appear  to  be  on 
ma  important  head.  The  tractt  for  the  control  of  the  motor  cranial  nerves  (with 
we  probable  exception  of  the  oculo-motor  series),  and  the  pyramid  tract,  which 
cwveys  voluntary  impulses  to  the  extremities  of  the  opposite  side,  as  ascertained 
by  Flechsig,  are  situated  in  and  behind  the  e^tmu  of  the  internal  capsule,  that  is 
m  ite  anterior  part  of  the  posterior  or  thatamo-UHiicMlar  division,  not  in  the 
anterior  half  or  two-thuxls  of  the  capsule"  as  Seguin  (Lectures  on  Localization, 
JUDICAL  Rbcord,  vols.  xiiL  and  xxv.)  and  a  few  others  represent  it.  Where 
nose  who  are  familiar  with  cerebral  topography,  who  have  actually  manipulated 
■ains,  besides  being  active  as  original  and  laborious  contributors  to  the  subject  of 
orebral  patholoey,  err,  it  is  not  to  be  wondered  at  that  compilers  should  foUow. 
^umey  (Applied  Anatomy  of  the  Nervous  System,  pages  44,  48,  and  91)  repeat- 
edly makes  the  same  erroneous  statement  Perhaps  the  loose  ideas  on  this  sub- 
IKt  we  m  part  due  to  the  &ulty  conceptions  of  the  situation  and  course  of  the  in- 
tenal  capmile  which  such  dugrauns  as  that  of  Daleon,  copied  on  page  aa  of 
Ramiey's  book,  are  calculated  to  foster.  Here  die  pyramid  fibres  of  the  capsule  are 
actuatty  made  to  decussate  m  the  pons !  It  is  best,  in  order  to  avoid  confusion,  to 
speak  of  the  anterior  of  the  two  great  divisions  of  the  capsule  which  lies  between  the 
KtoHaadad  slope  of  ^^caudatvs  and  the  meso-cephalic  slope  of  the /*w//Vji<Atrir, 
a  Ite  caudo-leaticular  capsule  "  and  of  the  posterior,  which  ties  between  the  meso- 
ondad  slope  of  the  Unticnlaru  and  the  ccto-cephalic  slope  of  the  tAalamtu.  as 
ae  'dMUamo-lcnticubur  capsule."  It  is  in  the  latter  alone  that  the  "anterior" 
Mr  dsvision  and  the  /'posterior'*  sensory  division  are  located  (Flechsig, 
Womcke,  StrOmpeU,  etc).  The  sonalled  external  capsule,  which  lies  between  the 
«alfaceofthe/wi/*f«i/jri*and  ±a  ciautiruim^  might  be  distinguished  by  the 
Knn  "daustio-lenticular'*  capsule. 


known  by  the  empirical  but  crucial  tests  of  the  physiolo- 
gist and  pathologist  Anatomical  methods  must  supply 
the  deficiency,  at  least  for  the  present,  and  a  small  army 
of  anatomists,  following  the  lead  of  Gall,  Meynert,  Foville, 
and  Gratiolet,  and  working  with  the  improved  methods 
of  Stilling,  Gudden,  and  Flechsig,  are  rapidly  completing 
the  survey  of  the  course  taken  by  the  great  nerve-tracts, 
discovering  their  ganglionic  and  peripheral  terminations, 
and  enabling  the  physiologist  to  infer  the  r6le  they  play 
in  the  machinery  of  thought  and  action. 

In  the  course  of  these  researches  it  has  become  noted 
as  one  of  the  most  significant  facts,  that  there  is  a  re- 
markable difference  in  kind  between  the  course  of  the 
tracts  of  voluntary  motion  and  those  which  convey  sen- 
sorial impressions — a  discrepancy  which  may  yet  lead 
to  a  complete  revolution  in  the  views  generally  enter- 
tained of  the  central  nervous  functions.  I  refer  to  no 
less  startling  an  innovation  on  the  current  views  than 
the  possible  one,  that  certain  of  the  tracts  which  are  or- 
dinarily regarded  as  sensory,  and  hence — almost  self-evi- 
dently — as  centripetal,  are  really  the  seat  at  the  same 
time  of  centrifugal  functions. 

While  the  tract  of  voluntary  motility  directed  to  the 
extremities  runs  clear  of  all  ganglionic  interruption  from 
the  supreme  centre,  the  cortex,  to  the  gray  matter  of  the 
cord,  not  one  of  the  sensory  tracts  has  been  traced  to  a 
cerebral  termination,  without  encountering  a  ganglionic 
interruption.  The  columns  of  Burdach  and  Goll,  for  ex- 
ample, terminate  in  the  nuclei  of  those  columns,  the 
direct  myelo-cerebellar  tract  runs  into  the  cerebellum,  and 
other  less  individualized  fibre*systems,  which  may  possibly 
have  a  relation  to  sensory  functions,  are  connected  with 
and  provisionally  at  least  terminate  in  some  one  or  other 
ganglionic  way-station  or  terminus. 

If  on  comparing  the  relative  development  in  various 
animals  of  the  internodial  ganglia  connected  with  these 
tracts,  it  were  found  that  they  are  less  developed  in  higher 
than  in  lower  animals,  it  might  be  inferred,  as  I  urged 
with  regard  to  certain  other  ganglia  and  tracts,  that  they 
represented  necessary  steps  in  phyllogenetic  development, 
destined  like  the  human  tail,  and  the  notochordal  relic 
in  the  ligamentum  suspensorium  dentis  epistrophei^  to  be- 
come obsolete.  For  nerve-tracts  subservient  to  higher 
functions  do  exhibit  a  tendency  to  emancipate  themselves 
from  ganglionic  interruptions,  probably  because  a  direct 
telegraphic  connection — cceteris  paribus — is  a  more  per- 
fect mechanism  than  one  which  has  to  pass  many  inter- 
rupting stations. 

But  this  is  not  the  case  with  regard  to  the  ganglia  under 
consideration.  Their  interrupting  stations,  such  as  the 
nuclei  of  the  columns  of  Goll  and  Burdach,  and  the 
dentated  nucleus  of  the  olive,  attain  their  highest  develop- 
ment in  man  and  the  anthropoid  apes.  There  is  as  much 
of  higher  individuality  in  the  varying  contours  of  the  last- 
named  body,  as  there  is  in  the  cerebral  hemispheres  them- 
selves ;  just  as  the  monkeys  alone  resemble  man  in  the 
type  of  cerebral  convolution,  so  they  alone  of  all  animals 
present  anything  like  the  same  character,  relations,  and 
degree  of  olivary  corrugation.*  If  there  is  any  inference 
to  be  drawn  as  to  the  physiological  importance  from  rela- 

*  And  this  not  as  an  expression  of  generally  high  cerebral  development  in  the 
anthropomorphse,  but  of  affinity  in  codlogical  position,  and,  what  is  practically 
equivalent,  of  peripheral  disposition,  for  the  elephant  and  porpoise,  with  far  more 
complexly  convoluted  hemispheres  than  man  even,  have  simpler  olivary  bodies, 
resembling  those  of  their  humbler  congeners,  the  hog  and  rhe  sea-lion.  Meynert 
is  utterly  at  sea  where  he  refers  to  ttie  remarkable  development  of  the  olive  in 
marine  mammals,  for  the  same  elevation  passes  as  the  pyramids  in  Huguenin'^ 


394 


THE  MEDICAL  RECORD. 


[October  ii,  igg^^ 


tive  development,  these  interrupting  stations   must  be 
regarded  as  important  factors  in  the  central  laboratory. 
This  is  almost  the  same  tale  as  that  which  might  be  told 
of  the  cerebellum  ;  a  ganglion,  which  may  be  regarded  as 
a  gigantic  way-station,  in  which  auditory  and  spinal  tracts 
meet,  and  are  continued  brainward,  through  cerebello- 
cerebral  fasciculi.     It  was  not  so  very  long  ago  supposed 
that  the  cerebellum  as  a  "  lower  centre  "  was  crowded  out 
-by  the  higher  cerebrum  in  the  ascending  animal  series, 
whereas  the  fact  is  that  this  ganglion  is  vastly  larger  and 
more  intricate  in  higher  animals  than  in  lower  ones,  and 
«hows  an  individuality  in  the  type  of  its  foliated  arrange- 
ment, comparable  to  that  adverted  to  in  the  case  of  the 
olivary  nuclei. 

It  being  thus  evident  on  structural  grounds  that  the  gan- 
glionic enlargements  in  which  certain  spinal  tracts  appear 
to  terminate  have  an  object,  which  could  not  be  fulfilled 
if  those  tracts  ran  directly  to  the  cortex,  we  must  look  to 
the  other  connections  of  such  ganglionic  masses  for  an 
explanation  of  that  object.  To  take  a  hypothetical  case. 
Suppose  the  cerebellum  received  fibres  from  the  skin 
through  the  "  sensory  tracts  "  in  the  cord,  and  from  the 
semicircular  canals  through  the  auditory  nerve,  and  de- 
spatched another  tract  to  the  cerebrum ;  assuming  that  the 
>f  direction  of  functional  transmission  were  in  all  these 
tracts  toward  the  cerebrum,  there  could  be  but  one 
conclusion  :  that  the  cerebellum  served  to  co-ordinate  and 
fuse  space  sense  perceptions  from  the  skin,  and  such 
from  the  semicircular  canals,  and  acted  as  an  informing 
depot  for  the  cerebrum  ;  the  latter  is  through  its  inform- 
ant, which  spares  the  cerebrum  the  task  of  co-ordinating 
these  impressions  into  a  united  general  space  sense, 
enabled  to  guide  motion  in  accordance  with  the  latter.* 

The  probable  object  of  the  intemodial  or  interrupting 
ganglia  is  the  mediation  of  some  functional  combination. 
The  manifold  interruption  of  the  tracts  of  sensation,  as 
contrasted  with  the  direct  course  of  the  tract  of  voluntary 
motion,  hence  appears  as  the  anatomical  expression  of 
the  fact  that  the  motor  impulse  is  a  comparatively  simple 
step,  but  that  the  building  up  of  the  contact  and  space 
senses  which  guide  such  motion  to  a  skilful  purpose  is  a 
far  more  intricate  and  laborious  task,  which  is  thrown  on 
the  centripetal  tracts,  and  hence  requires  a  greater  ana- 
tomical complication. 

I  need  but  cite  briefly  a  few  facts  recently  observed  by 
me  in  an  interesting  case*  which  justify  the  surmise  above 
expressed,  that  certain  tracts  physiologically  and  ana- 
tomically regarded  as  centripetal  really  may  convey  func- 
tions centrifugally  in  a  part  of  their  course.  An  elderly 
gentleman,  after  a  small  hemorrhage  in  the  pons,  which 
caused  unilateral  ataxia  of  the  opposite  extremities,  lived 
six  years,  during  which  time  an  intense  secondary  degen- 
eration developed  in  the  descending  direction,  and  termi- 
nated after  decussating  in  the  opposite  nuclei  of  the  col- 
umns of  GoU  and  Burdach,  which  were  likewise  atrophic. 
Now  as  far  as  secondary  degenerations  follow  any  law,* 
it  is  supposed  that  if  a  ganglion  degenerates  together  with 
an  appended  tract,  that  both  must  belong  to  the  same 
physiological  system.  The  columns  of  GoU  and  the 
upper  part  of  the  columns  of  Burdach  degenerate  centrip- 
etally,  that  is,  upward,  or  toward  their  nuclei.  The  dis- 
eased tract  in  my  patient  had  degenerated  centrifugally, 
that  is,  cordward,  and  hence  from  an  opposite  direction, 
also  toward  these  nuclei.  Here  is  an  unquestionable  in- 
stance  in  which  two  segments  of  the  same  tract — for  the 
upper  segment  must  be  regarded  as  in  part  the  cephalic 
continuation  of  the  lower — degenerate  toward  an  inter. 


>  The  (acts  happen  to  justify  this  hypothesis,  to  some  extent.  As  bearing  on 
what  the  wntcr  said  about  the  possibihty  of  tracts  customarily  regarded  as  centrip- 
etal conveying  centrifugal  funclions»  it  may  be  well  to  refer  to  the  fact  that  if 
Flechsig  s  suspicion,  that  the  direct  myclo-cerebellar  tract  is  centrifugal,  turn 
out  to  be  well  founded,  that  the  cerebellum  may  exert  a  direct  influence  on  a  cer- 
tain class  of  movements,  without  the  intervention  of  the  cerebrum  at  all.  This 
would  but  increase  the  force  of  the  remarks  made  in  the  text,  as  to  the  importance 
of  the  interrupting"  and  "co-ordinating"  stations.  The  above  idea  has  been 
borroweil,  with  others,  by  Ranney. 

a  This  case  has  been  reported  elsewhere,  to  be  hereinafter  referred  to,  when  the 
questions  involved  will  be  more  fully  discussed. 

3  I  question  whether  they  do  follow  such  law  as  invariably  as  some  assume. 


polated  ganglion  when  diseased,  justifying  the  assamption 
that  functional  impressions  converge  toward  it,  though 
not  excluding  the  possibility  of  a  continuous  transmission 
brainward  of  sensory  impressions  *  at  the  same  time. 

I  have  considered  it  necessary  to  make  these  introduc- 
tory remarks,  because  to  me  the  impression  seems  to  pre- 
vail  that  all  that  is  necessary  to  understand  the  anatomical 
part  of  the  cerebral  mechanism  is  the  tracing  of  the  cen- 
tripetal tracts  to  the  muscles  in  which  they  terminate,  and 
the  centrifugal  ones  to  the  cortical  fields,  from  the  periph- 
eries,  whose  impressions  they  convey  to  them.  This 
is  important  and  essential,  but  it  does  not  exhaust  the 
duties  of  the  anatomical  psychologist,  and  is  not  even 
feasible  in  the  case  of  many  fasciculi.  What  I  said  some 
years  ago  *  with  regard  to  the  functions  of  nerve-centres 
generally,  "  That  day  is  past  when  it  could  be  considered 
legitimate  to  refer  every  phenomenon  provoked  by  an 
intracranial  experiment  to  an  altered  activity  of  any  single 
centre  ! "  naturally  applies  also  to  the  nerve-tracts  whose 
connection  with  the  nerve-centres  is  a  factor  in  the  func- 
tion of  the  latter. 

With  these  preliminary  remarks,  I  have  intended  to 
pave  the  way  for  the  understanding  of  the  lemniscus :  a 
nerve-tract  of  at  least  equal  importance  with  that  of  the 
pyramids,  an  importance  which  is  just  being  recognized, 
and  which  from  its  manifold,  systemic,  and  topographical 
relations  offers  an  opportunity  for  the  discussion  of  many 
new  or  imperfectly  understood  features  of  isthmus 
anatomy. 

II. — External  and  Gross  Anatomy  of  the  Lemnis- 
cus. 

On  the  outer  (lateral)  face  of  the  mesencephalon,  that 
isy  on  the  slope  which  intervenes  between  the  corpora 
quadrigemina  and  the  bulging /^j  of  the  cerebral  pedun- 
cle of  each  side,  there  is  a  distinctly  marked  triangular 
field,  known  as  the  lemniscus  or  laqueus. 

This  is  not  merely  a  surface  feature  of  the  brain- 
isthmus  (or  axis),  but  the  exposure  of  a  great  brain- 
tract,  which  in  this  particular  area  is  uncovered  by  other 
nerve  tissues,  and  elsewhere  is  deeply  imbedded  in  the 
substance  of  the  thalamus  region,  Hait  pons^  and  passing 
through  the  oblongata^  becomes  intimately  related  with 
the  ganglionic  elements  of  the  great  centripetal  columns 
of  the  cord,  namely,  the  nuclei  of  the  columns  of  GoU  and 
Burdach,  as  well  as  the  dentated  body  of  the  olive.  Just 
as  the  columnar  elevations  of  the  oblongata,  known  as 
the  pyramids,  represent  only  a  small  segment  of  that 
great  system,  the  will-tract,  to  which  they  have  given 
the  anatomical  name  of  *'  pyramid-tract,*'  so  the  surface 
area  of  the  lemniscus  indicates  but  an  insignificant  por- 
tion of  the  great  tract  which  bears  the  same  designation. 

Haller '  discovered  the  lemniscus,  describing  its  situa- 
tion and  shape,  but  to  Reil  *  is  owing  the  credit  of  having 
recognized  that  the  triangular  field  discovered  by  Haller 
is  only  the  surface  denudation  of  an  important  system  of 
fibres.  He  found  that  it  was  not  in  connection  with  the 
pyramids,  though  some  admixture  of  the  fibres  of  the  fillet 
and  the  pyramid  was  alleged  by  him,  and  traced  it  to  the 
situation  to-day  known  as  the  stratum  of  the  fillet 
(Schleifenschicht).  He  later  claimed  that  it  passed  be- 
tween the  olivary  nuclei  and  the  pyramids  in  the  ob- 
longata, and  became  indistinguishably  fused  with  both  of 
these  bodies.  Rosenthal  undertook  to  correct  this  latter 
statement,  which,  as  far  as  the  pyramids  are  concerned, 
is  partly  true,  for  my  own  case  demonstrated  the  existence 


*  Or  of  hitherto  unsuspected  centrifugal  transmission  cordward.  The  oc^umns  of 
GoU  may  occasionaUy  d^enetate  downward  or  simultaneously  with  their  nuclei :  at 
least  this  seems  to  have  been  so  in  Sioli's  case  (Archiv  f.  Psychiatrie,  xi.,  3,  p.  693.' 
This  surmise  would  offer  the  explanation  of  possible  physiological  transitioB  lor  the 
case  of  some  rodents,  like  the  rat,  in  whom,  according  to  Fleoiiaj^,  ^e  fibres  of  the 
'ivc  (: )  pyramidal  decussation  enter  the  posterior  columns. 

>  llie  Architecture  of  the  Oblongata,  N.  Y.  Medical  journal,  September,  1881. 
It  is  refreshing  to  find  this  identical  conception  emanatmg  from  another  writer  in 
the  same  journal  several  years  after.  Unfortunately  the  context  of  his  coodusion 
furnishes  no  hint  as  to  the  method  by  which  he  arrived  at  an  opinion  so  similar  in 
its  phraseology  to  the  writer's.  It  is  in  fact  a  disconnected  plagiarized  sentence, 
like  another  previously  referred  to  as  appropriated  from  the  same  source. 

'  Elementa  IV.,  p.  175.    According  to  Burdach.) 

*  Reil*s  Archiv,  ix.,  p.  149. 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


395 


of  degenerated  fasciculi  in  the  otherwise  healthy  pyramid, 
and  these  were  connected  with  the  degenerated  inter- 
ohVary  field. 

The  discovery  of  Hallei  was  ignored  by  the  anatomists 
Hrho  described  the  mesencephalon  after  his  time,  and 
before  that  of  Reil.  Vicq  d*Azyr,*  whose  plates  are 
usually  singularly  true  to  nature,  represents  the  lateral 
field  of  the  mesencephalon  as  a  uniform  rounded  surface, 
and  neither  designates  nor  describes  the  lemniscus,  while 
Gall  *  gives  an  excellent  illustration,  particularly  accurate 
as  regards  the  deeply  depressed  acute  apex,  but  does 
not  refer  to  it  (Plate  XIII.,  under  "  30  "). 

Burdach,  who  mainly  follows  Reil's  description,  gives 
an  accurate  account  in  his  text,  but  his  artist  erroneously 
represents  the  fourth  pair  as  aris- 
ing from  each  lemniscus,  instead 
of  from  the  valvula  (Plate  IV.). 
The  lateral  aspect  is  very  well 
represented  in  the  fifth  plate  of 
the  same  work. 

Reil  recognized  comparatively 
clearly  that  the  lemniscus,  in 
passing  through  the  pons,  is  dis- 
tinctly separated  from  the  trans- 
verse fibres  of  the  cerebellar  M 
system,  and  in  many  of  the  writ- 
ings and  illustrations  of  his  day, 
it  may  be  seen  that  the  so-called 
"  bundle  from  the  pes  to  the  teg- 
mentum," described  by  Henle,' 
was  considered,  at  least  in  its 
posterior  division,  a  part  of  the 
lemniscus. 

One  of  the  sharpest  lines  of 
separation  of  nerve-tracts  is  the 
one  which  in  the  pons  region 
separates  the  lemniscus  and  the 
transverse  pons  fibres.  This  line 
of  separation  was  misinterpreted 
by  the  older  anatomists.  Vicq 
d'Azyr*s  artist,  one  of  the  most 
conscientious  draughtsmen,  has 
permitted  his  artistic  interpreta- 
tion to  encroach  on  anatomical 
truth,  more  in  this  than  in  any 
other  detail  of  encephalic  anat- 
omy. On  Plate  XXV.  he  makes 
a  round  nugget  of  the  pons, 
completely  encasing  it  in  a 
whitish  shell,  of  which  the  dor- 
sal half  is  the  bundle  from  the 
pes  to  the  tegmentum,  while  the 
ventral  portion  represents  the 
superficial  transverse  fibres  of 
the  pons.     The  joining  portions 

are  altogether  imaginary.  He  apparently  recognized  the 
continuous  tract  of  the  above-mentioned  bundle,  but  en- 
graved it  from  memory,  notes,  or  hasty  sketches — he  cer- 
tainly had  not  the  specimen  before  him — and  confounded 
the  posterior  longitudinal  fasciculus,  the  stratum  inter- 
medium, and  the  tracts  from  the  mamillary  body,  dupli- 
cating them  in  one  place  so  as  to  be  entirely  incompre- 
hensible. 

The  bundle  overlying  the  line  of  separation  is  very  dis- 
tinctly and  correctly  represented  on  Plate  XII.  of  Gall's 
atlas. 

The  figure  reference  (85)  reads  :  '*  Ligne  de  separation 
entre  les  parties  ant^rieures  (ventral)  et  post^rieures 
(dorsal)  de  la  masse  c6r6brale  ascendante,"  and  evidently 
relates  to  the  sharp  line  of  demarcation  which  separates 
this  fibre  mass  from  the  transverse  pons  fibres.  The 
course  of  the  tract  as  visible  in  sagittal  sections  is  cor- 

»  Tratid  d'Anatomie  et  de  Physiolos;ie,  1786,  tSmc  icrc,  Plates  XXVI  I.  and 

*  Anatomic  et  Pbysiologie  du  Syst^me  Nerveux  et  du  Cerveau  en  particulier. 
Paris,  x8z8. 
'  Aiiatomie  des  Mcnschen,  iti.,  Z87X. 


rectly  represented  as  being  between  the  substantia  nigra 
{Ganglion  Soemmeringii,  E.C.S.),  and  the  olivary  region.' 
I  have  sections  in  my  collection  which  are  exact  reproduc- 
tions of  this  plate,  a  signal  confirmation  of  the  accuracy 
of  Gall's  delineations. 

In  order  that  the  general  reader  may  not  become  lost 
in  the  obscurity  of  the  brain-axis  terminology,  I  may 
be  pardoned  for  digressing  here  to  explain  the  meaning 
of  some  of  the  terms  already  used,  and  the  topography  of 
the  parts  with  which  we  are  about  to  deal. 

The  brain  axis  or  isthmus  is  the  continuation  upward 
of  the  spinal  cord.  It  is  the  common  trunk  (hence  the 
German  term  "Hirnstamm"  or  brain  trunk)  from  which 
the  two  cerebral  hemispheres  crop  out  like  swollen  ter- 


FiG.  z. — Brain  Axis  or  Isthmus,  with  the  Obbngata  nearly  entirely  removed,  bv  a  sweep  of  the  knife  through  the 
Acusdc  Stria:.  M  represents  this  cut  surface,  on  which  the  contours  of  the  raph^,  olivary  nuclei,  pyramids,  and 
resttform  columns  are  laintly  mdicated.  The  isthmus  is  tilted  in  such  a  way  that  the  lateral  and  superior  (dorsal) 
i-. •„   f 1      ?.L.-..- ,. j_  _•/•.!_    _i .. 1_ X.  both  (ideal)  retinal  planes  of  the  observer 

lus  deviates  from  this  plane  forward  45", 


(aces  are  simultaneously  visible ;  in  other  words,  if  the  plane  passing  through  t 

_  vertical  and  corresponding  to  the  page,  the  axis  of  the  isthmus  deviates  trom  this  pU 

and  upward  in  the  plane  a/*.    The  following  indicate  the  principal  parts.    A,  of  the  oblongata  :  Af,  cut  surface 


be  regarded  as  ' 


auditoiv  nerve  root'  B,  of  the  pons  :  pB^  cut  surface  ^pontU  brachium  (middle  cerebellar  peduncle) ;  mB^  ditto  of 
myeloSrachium  (posterior  cerebellar  peduncle)  :  tB,  tB,  ditto  of  tegm*Hta4>rachium  (anterior  cerebellar  peduncle)  ; 
those  of  both  sides  are  connected  by  die  divided  vaivuia^  of  which  /r  indicates  the  Jreuulum.  Between  the  cut 
edge  of  the  oblongata  section  and  the  semicircular  combined  section  of  the  cerebellar  peduncles,  the  anterior  half 
of  the  founh  ventnde  is  set  like  a  picture  in  a  frame  ;  xv  indicates  the  median  sulcus^  which  anteriorly  deepens 
into  the  aqueduct  under^,  while^  indicates  the  fovea,  from  which  a  groove  runs  demarcating  part  of  the  auditory 
triangle.  The  other  references  are  :  6,  abducens  (sixth)  nerve  roots  ;  7,  ditto  facial ;  5,  ditto  trigeminus  ;  *,  the 
iractus  iuterradicularis  pontis,  named  and  described  by  the  author  in  the  Am.  Jour,  of  Neur.,  May,  1884  :  rf 
the  recesstu  facialis^  named  and  described  jn  the  same  number.  C,  of  the  mesencephalon  :  fr^  frenulum  valvula  ; 
ba^  anti-brachium  ;  3/,  3/^,  post  brachium :  Gi^  ganglion  geniculatutn  internum  ;  Tpt^  tracius  transversus 
peduncularis  (crossing  the  pes).  The  corpora  quadrigemina  are  so  characteristic  that  they  require  no  designation. 
JD,  of  the  thalamus  segment :  Tpv^  pulvinar;  A,  habenula  ;  /,  cut  surfaces  of  tf/f^A/xif  (pineal  gland) ;  Ge^  pin^lion 
grnicttlatum  externum,  which  is  really  only  a  thalamic  nucleus  ;  TV,  optic  tract :  2,  optic  nerve ;  ♦♦,  reflection  of 
endy  ma  of  lateral  ventricle  :  t,  insinuation  ox  branch  of  optic  tract  between  Gi  and  thalamus  to  pass  to  ba :  tt,  sin- 
gular tract-like  elevation  of  thalamus  sHrflUx,  hitherto  undescribed.  and  not  equally  well  devek^>ed  in  all  brains. 

minal  branches,  while  the  cerebellum  is  an  excrescence 
of  the  trunk  itself. 

In  its  general  shape,  excluding  the  inflections,  it  may  be 
compared  to  an  inverted  truncated  cone,  for  as  we  follow 
it  up  toward  the  cerebral  hemispheres,  it  becomes  wider 
and  deeper,  enlarging  progressively  in  all  directions.  The 
lower  small  end  is  the  spinal  termination,  the  upper  wide 
end  is  the  cerebral  or  thalamo-crural  end.  The  entire 
axis  may  be  considered  under  the  following  four  heads : 
I.  Thalamic  division.  2.  Mesencephalon  (region  of  the 
corpora  quadrigemina).  3.  Pons.  4.  Oblongata.  In  the 
main  the  thalamic  division  consists  dorsally  of  two  great 
flaring-out  masses,  separated  by  the  third  ventricle.  Ven- 
trally  it  includes  the  subthalamic  region  and  that  part  of 
the  crus  which  prepares  to  merge  into  the  internal  cap- 
sule. 

'  The  mesencephalon  is  marked  dorsad  by  the  four 
beautiful  eminences  of  the  corpora  quadrigemina,  ventrad 
by  the  symmetrical  and  cylindrical  prominences  of  the 

^  Respectively  references  30  and  a  of  the  same  plate. 


396 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


crura  (pes  portion).  The  transverse  section  in  adult 
man  exhibits  a  black  crescentic  line  on  each  side  which 
sharply  separates  the  crus  proper  (pes)  from  the  dorsal 
part,  which  merges  into  the  corpora  quadrigemina  and  is 
known  as  the  tegmentum.  This  black  crescentic  line  is 
the  substantia  nigra  of  Soemmering.  It  constitutes  the 
most  important  boundary  line  in  the  deep  anatomy  of  the 
brain  axis. 


Fig.  3. — Section  flat-wise,  that  is,  parallel  to  the  base  of  the  brain  axis,  through  the  Thalamic  MeseHce^katcn^ 
P0Hty  and  Oblongata,  extending  to  the  Spinal  Cord.  It  dips  a  little  lower  on  the  right  than  on  the  left  side,  and 
to  this  the  slif^ht  asymmetry  of  the  ligure  is  due.  The  following  tigure  references  relate  to  the  thalamic  and  sub- 
thalamic r^ions  :  H,  habenular  tract :  7V.  m.^  **,  m.  ('.  z,  and  m,  i,  a,  medullary  lamina;  of  thalamus  ;  C 
>m/.,  commusuia  posterior ;  ///.,  third  ventricle.  The  following  relate  to  the  mesencephalon :  Aq.  Gr.^  aque- 
duct gray  matter ;  pl/.^  posterior  longitudinal  fasciculus  of  the  t^mentum ;  <.,  part  of  the  descending  trigemmus 
root^  G.  certbli.f  the  du«ct  tract  from  the  cerebellum  to  the  posterior  part  of  the  cerebrum,  discovered  by 
Gratiolet^  confirmed  by  Flechsigj  and  which  courses  through  the  outer  part  of  the //x  ptdunculi  ;  Tepnt.  Br.X., 
decussation  of  tegmenta  brachium  or  brachium  conjunctivum,  also  known  as  Wemekinck^s  commissure.  The 
following  refer  to  the  pons  :  rad.  and  rad.  2,  auditory  and  facial  nerve  roots  cut  across  :  hh,  nuclei  of  pons 
gray  ;  *,  cerebellar  origmof  G.certblL;  Pont,  Br.^  pontis  brachium^  or  middle  peduncle  of  cerebellum  divided 
across.  The  following  relate  to  the  oblongata  :  Pyr.  X.,  decussation  of  true  pyramids  ;  OL  dent.^  dentated  or 
main  port  of  olivary  nucleus  ;  01.  int.,  intenud  auxiliary  part  of  same.  *  The  other  references  relate  to  the  lem- 


niscus tracts,  and  are  explained  in  the  text. 

from  the  brain  axis  of  a  Swede,  whose  brain  I  secured  through  the  courtesy  of  ProfessOT  James  iJ.  Little. 


llie  specimen  was  stained  by  carmine,  being  cut  in  my  microtome 
'  '"    '  -  .     - .   .       j^ 


was  hardened  m  bichromate  of  potash. 

The  pons  exhibits  dorsad  the  upper  half  of  the  floor  of 
the  fourth  ventricle.  Ventrad  a  bridge  of  nerve-substance 
apparently  jointing  the  cerebellar  hemispheres. 

If  the  beginner  will  conceive  a  conical  piece  of  wood, 
whose  base  is  turned  upward,  split  by  an  axe,  while  a  band 
is  thrown  around  the  middle  of  its  length  to  prevent  the 
split  from  extending  through  to  the  apex  of  the  cone,  he 
will  have  a  crude  idea  of  the  relations  of  the  pons  as  seen 
at  the  base  of  the  brain.  The  two  parts  on  each  side  of 
the  split  are  the  pedal  crura;  the  split  is  the  interpedun- 


cular or  intercrural  depression  ;  the  belt  is  constituted 
by  the  bridging  portion  of  the  pons,  below  which  the  un- 
split  part  represents  the  oblongata. 

The  pes  and  tegmentum  are  separated  in  the  pons  by 
the  sharp  line  of  separation  alluded  to  in  the  historical 
introduction. 

In  the  oblongata,  it  is  impossible  to  make  as  clear  a 
division  of  the  tegmental  and  pedal  part  of  the  brain  axis 
as  in  the  pons  and  mesencep'ialon. 
The  pyramids  are  the   true  repre- 
sentatives of  the  pes. 

The  exterior  of  the  brain  axis  is 
sculptured  into  numerous  eminences 
— some  of  them  in  very  high  relief 
— and  depressions.  Of  the  emi- 
nences, some,  like  the  tudfr  cine- 
reum  of  Rolando,  the  olives,  and 
the  clavas,  are  due  to  the  accumula- 
tion of  gray  matter  beneath  the  sur- 
face at  that  point ;  others,  like  the 
pyramids,  the  restiform  columns, 
the  crura,  are  due  to  the  prominence 
at  certain  points  of  the  surface  of 
the  great  nerve-tracts.  It  is  to  this 
class  that  the  eminence,  known  as 
2«iif^J5>V'  the  lemniscus,  belongs. 
^  As  represented    in   the  figure  L 

the  elevation  of  the  lemniscus  is  a 
flat  triangular  field,  with  one  trun- 
cated and  two  sharp  angles.  Of  the 
latter,  one,  the  superior  (dorsal), 
comes  in  contact  with  the  super- 
ficial origin  of  the  fourth  pair  of 
cranial  nerves.  The  anterior  corre- 
sponds to  the  (apparent)  junction 
of  the  crusta  znd  J^ost-^rachium.' 

The  posterior  truncated  angle  is 
overlapped  by  the  redundant  growth 
of  the  pons.  While  the  anterior  side 
of  the  triangle — that  is,  the  one  con- 
necting the  superior  and  anterior 
angles — sinks  below  the  post-brach- 
ium,  the  inferior  side  is  in  contact 
with  the  dorso-lateral  edge  of  the 
crus,  and  the  ixjsterior  (on  which  the 
light  in  the  figure  falls)  rises  in  bold 
relief,  cropping  out  over  the  tegmenta 
brachium. 

These  surface  appearances  indi- 
cate the  actual  relations  of  the  lem- 
niscus tract  to  some  extent  It  may 
be  regarded  as  a  flat  band,  which  is 
dragged  out  of  the  substance  of  the 
pons  to  overlap  the  tegmenta  brach- 
ium^ to  be  overlapped  itself  by  the 
crus  and  the  post-brachium  ;  in  its 
known  course  it  extends  from  the 
thalamus  region  to  the  lowest  levels 
of  the  oblongata.  Unlike  the  pyra- 
mid tract,  which  is  a  single  united 
system  of  uniform  physiological  rela- 
tions, the  lemniscus  tract  includes  a 
number  of  nerve-bundles  having  dif- 
ferent destinations  and  dififerent  gan- 
glionic connections.  Indeed,  with 
our  increasing  knowledge  of  this  part 
of  the  cerebral  projection  system,  it  will,  I  think,  become 
recognized  that  the  includmg  of  all  these  bundles  under 
one  generic  term  is  improper  and  misleading.  One  feature 
is  found  with  all  of  them,  that  they  are  (in  part,  at  least) 
related  to  functions  regarded  as  centripetal  and  sensorial, 
as  far  as  we  may  draw  surmises  from  structure.    The  part 


^  Arm  of  the  posterior  pair  of  the  corpora  (]uadrigemina.  In  the  figure  an  in- 
teresting variation  is  shown  ;  this  arm  exhibits  iu  two  characteriscic  divisions  [h 
and  bj/)y  and  at  the  end  of  the  pointer,  bp',  the  intumescence  known  as  the 
gangiwi  geniculatum  mediaU.    j 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


397 


of  the  brain  axis,  in  which  the  lemniscus  tracts  are  seen 
in  their  clearest  relation,  and  where  the  various  designa- 
tions of  authorities  are  most  in  accord,  is  exposed  by  a 
transverse  section  through  the  posterior  pair  of  the  cor- 
pora quadrigeniina  or  a  little  behind  this,  through  the 
valvular  Typically  each  lemniscus  stratum  consists  of 
an  L-shaped  area,  so  situated  that  the  area  of  each  lem- 
niscus  stratum  touches  the  median  (line)  raph6  with  the 
free  end  of  the  horizontal  branch,  thus  L  -I  Even  in 
sections  which  are  inclined  to  the  axis  more  or  less,  as  in 
Figure  2,  a  similar  appearance  is  noted.  Here  a  on  the 
right  side  represents  the  horizontal  branch,  and  2  on 
both  sides,  3  and  4  on  the  right  side,  represent  the  verti- 
cal portion. 

This  figure  indicates  at  the  same  time  as  much  of  the 
entire  course  of  the  lemniscus  tracts  as  any  one  section 
can.  It  is  seen  to  extend  from  above  the  pyramidal  de- 
cussation at  e  between  the  olives  at  //,  then  spreading 
over  an  immense  area,  along  6,  5,  4,  3,  2,  i,  to  the  thai- 
ami,  gradually  becoming  more  and  more  remote  from  the 
median  raphe,  while  another  detachment  remains  near  to 
it,  at  r,  ^,  and  a.  As  in  all  sections  of  this  character,  the 
apparent  contimuity  of-  the  fibres  is  accidental,  the  vari- 
ous parts  are  intermingled  somewhat ;  but  as  other  sec- 
tions and  other  methods  of  study  show,  all  of  them  ap- 
pertain to  the  lemniscus  tract.  Let  us  proceed  to  dis- 
cuss these  in  detail. 

(To  be  continued.) 


SOME  POINTS  ON   THE  USE  OF   HEAT  AND 

COLD  IN  THERAPEUTICS.* 

By  JAMES  B.  HUNTER,  M.D., 

SURGEON  TO  THB  W01&AN*S  HOSPITAL,  NEW  YOKIC. 

I  AM  well  aware  that  the  subject  of  the  application  of 
heat  and  cold  in  therapeutics  is  a  very  large  and  com- 
prehensive one,  and  I  shall  attempt  no  more  than  to 
present  a  few  points  which  have  been  suggested  by  my 
own  experience. 

The  use  of  heat  and  cold,  in  some  form,  for  the  relief 
of  disease  is  almost  universal.  There  is  hardly  a  disease 
known  in  which,  at  some  sta^e,  it  is  not  deemed  neces- 
sary to  interfere  with  or  modify  the  existing  thermal  con- 
ditions, the  interference  varying  between  the  use  of  the 
actual  cautery  on  the  one  hand  and  of  ice  or  freezing  mix- 
tures on  the  other.  Between  these  extremes  the  ways 
and  means  of  modifying  temperature  are  very  numer- 
ous. The  necessity  for  some  interference  is  taken  for 
granted.  Some  of  the  most  advanced  professional  minds 
have  for  centuries  past  grappled  with  the  problem  of 
temperature  as  modified  in  disease — while  every  house- 
hold has  its  favorite  theories  and  maxims  concerning  the 
treatment  of  diseases  and  injuries  by  means  involving  a 
change  of  temperature. 

Yet,  notwithstanding  the  antiquity  of  what  may  be 
called  the  thermal  method  of  treating  disease,  and  its 
almost  universal  application  in  some  form,  there  exists  a 
surprising  difference  of  opinion  concerning  the  use  of 
heat  and  cold,  especially  as  to  which  of  these  powerful 
agents  should  be  employed  in  any  given  case. 

Professional  opinion  is  assuming  greater  uniformity  on 
this  point  with  the  advance  of  physiological  science ; 
but  popular  opinion,  which  often  reflects  the  professional 
opinion  of  a  former  generation,  differs  very  widely.  But 
whether  heat  or  cold  is  preferred,  public  opinion  is  al- 
ways in  favor  of  the  generous  use  of  one  or  the  other. 
A  gentleman  of  my  acquaintance  who  was  spending 
some  weeks  in  a  country  region,  chanced  to  sprain  his 
ankle.  He  was  carried  helpless  to  the  nearest  farm- 
house, where  he  was  prescribed  for  by  two  experienced 
matrons.  One  insisted  on  placing  the  limb  under  a 
stream  of  cold  water  from  the  pump,  and  keeping  it 
there  for  half  an  hour,  assuring  him  that  he  would  be 
able  to  walk  the  next  day  if  her  advice  were?  followed. 
The  other  advised  placing  the  injured  limb  in  a  pail  of 

>VaheofVieu8«en'«. 

*  Read  before  the  Practitioners'  Society  of  New  York,  October  3, 1884. 


water  nearlv  boiling  hot,  and  keeping  it  there  for  half  an 
hour,  promising  the  same  result  on  the  morrow.  Mean- 
while a  boy  was  despatched  to  the  nearest  village  for  medi- 
cal aid.  The  doctor  sent  for  was  not  at  home,  but  his 
assistant  visited  the  patient  promptly,  and  endorsed  the 
prescription  of  cold  water,  which  was  thoroughly  carried 
out.  On  his  return  in  the  evening,  the  senior  physician, 
thinking  the  patient  a  gentleman  of  some  consequence, 
hastened  to  see  him,  examined  the  ankle  carefully,  and 
advised  that  very  hoi  water  should  be  applied  during  the 
whole  night. 

A  similar  difference  of  opinion  is  common  both  in  the 
profession  and  out  of  it  Whether  it  be  a  sprained  ankle, 
an  inflamed  knee-joint,  a  bruise,  a  wound,  a  bum,  a 
fever,  there  is  often  a  radical  difference  of  opinion  as  to 
whether  heat  or  cold  will  give  the  greatest  relief  or  ac- 
complish the  most  good.  The  explanation  of  this  dif- 
ference of  opinion  is  probably  to  be  found  in  the  fact 
that  many  diseases  and  injuries  require  at  different  stages 
the  use  of  both  heat  and  cold,  and  that  the  indications 
for  the  use  of  either  one  are  not  always  clear.  In  the 
earliest  stages  of  inflammation  the  prompt  abstraction  of 
heat  often  suffices  to  abort  or  control  the  inflammatory 
process.  After  inflammatory  changes  have  taken  place, 
the  application  of  heat  to  the  same  part  may,  by  stimu- 
lating capillary  and  lymphatic  action,  hasten  absorption 
and  be  eminently  proper.  In  some  cases  this  explana^ 
tion  does  not  apply,  as  in  the  use  of  both  hot  and  cold 
water  for  the  arrest  of  hemorrhage,  or  of  hot  and  cold 
applications  for  the  relief  of  neuralgia,  regarding  which 
there  still  exists  some  difference  of  opinion.  It  is  safe 
to  say  that  in  no  given  case  is  it  a  matter  of  indifference 
whether  heat  is  added  or  subtracted.  The  same  differ- 
ence of  opinion  exists,  however,  as  to  the  use  of  some 
medicinal  agents  quite  opposite  in  their  effects. 

But  I  must  necessarily  pass  over  or  allude  very  briefly 
to  manv  points  which  suggest  themselves  in  connection 
with  this  subject. 

I.  I  will  first  consider  briefly  some  of  the  diseases  in 
which  the  abstraction  of  heat,  generally  or  locally,  is  de- 
manded. 

Typhoid  fever,  perhaps  better  than  any  other  disease, 
illustrates  the  good  effect  of  antipyretic  treatment.  Dr. 
G.  L.  Peabody,  in  a  valuable  statistical  paper  read  be- 
fore the  County  Medical  Association,  March  17,  1884, 
on  the  treatment  of  typhoid  fever,  says :  **The  effect  of 
high  temperature  is  very  deleterious  upon  normal  tissues, 
and  its  influence  is  distinctly  evil  in  reference  to  the 
possible  healing  of  intestinal  ulcers."  As  the  result  of 
his  own  experience,  and  a  careful  examination  of  the 
records  of  the  treatment  of  typhoid  fever  in  seventeen 
large  hospitals,  in  this  city  and  in  Europe,  those  of  the 
British  army  and  navy,  and  of  our  own  army.  Dr. 
Peabody  emphatically  endorses  the  use  of  cold  water  in 
the  treatment  of  that  disease.  He  shows  the  mortality 
to  be  only  seven  and  one-fourth  per  cent,  in  a  series  of 
over  eight  thousand  cases ;  and  a  series  of  two  hundred 
and  eleven  cases  in  Dr.'  Brand's  private  practice  all  re- 
covered under  the  antipyretic  treatment.  Dr.  Peabody 
laments  the  difficulty  of  introducing  the  practice  gener- 
ally, the  necessary  appliances  being  cumbersome  and 
expensive.  The  affusion  of  cold  water  he  has  not  found 
satisfactory ;  the  cold  coil  he  considers  unsuitable  ;  and 
the  cold  bath  the  only  really  efficient  method.  Now,  a 
cold  bath  in  the  immediate  proximity  of  a  patient  sick 
with  typhoid  fever  is  not  often  obtainable.  The  patient 
may  be  sick  in  a  country  house,  where  bath-tubs  are 
unknown ;  in  a  hotel,  where  they  are  fixed  and  re-, 
mote  from  the  patient's  room.  Even  in  a  private  bouse 
with  all  modern  appliances  it  is  not  an  easy  matter  to 
transfer  a  patient  from  a  sick-bed  to  a  bath-tub  and 
back  several  times  a  day  without  a  good  deal  of  dis- 
turbance to  the  patient,  and  an  abundance  of  physical 
help.  I  would  therefore  suggest  as  equally  efficient  and 
far  more  practicable  the  use  of  the  well-known,  but 
somewhat  neglected    Kibbee    fever-cot,  or  something 


398 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


equivalent  to  it.  This  cot,  which  was  first  devised  and 
used  by  Dr.  Kibbee  for  the  treatment  of  scarlet  fever, 
during  a  severe  epidemic  of  that  disease,  consists  essen- 
tially of  a  common  cot  or  frame  on  which  is  stretched 
strong  canvas  or  other  material  sufficiently  coarse  or 
open  to  permit  water  to  pass  through  it.  Under  this  is 
placed  a  rubber  sheet,  to  catch  and  convey  the  water  to 
a  pail  placed  at  the  foot  of  the  bed.  The  patient  lies 
comfortably  on  this  bed,  on  a  blanket  and  sheet,  but  of 
course  without  mattress.  Such  a  bed  can  be  improvised 
almost  anywhere  at  a  very  small  expense.  I  once  made 
a  very  efficient  one,  in  the  country,  with  an  old  coffee 
bag ;  and  I  once  used  an  ordinary  wire  mattress.  Any 
cot  covered  with  canvas  may  be  made  available  as  a 
water-cot  by  cutting  a  sufficient  number  of  holes  in  the 
canvas.  When  it  is  necessary  to  apply  the  cold  water, 
the  covering  of  the  patient  is  removed  from  the  body  (not 
from  the  extremities),  which  is  enveloped  in  or  covered 
by  a  sheet ;  upon  this  sheet  warm  or  tepid  water  is 
poured  gently  from  a  pitcher  or  watering-pot ;  the  tem- 
perature of  the  water  is  then  gradually  reduced  until  it  is 
sufficiently  cold.  The  stream  is  kept  up  for  ten  or  fifteen 
minutes,  a  dry  blanket  is  then  thrown  over  the  patient, 
and  sleep  generally  follows. 

Having  had  considerable  experience  in  the  use  of  this 
method  of  reducing  the  temperature  in  cases  of  peritonitis 
and  septicaemia  following  operations,  and  some  expe- 
rience with  it  in  typhoid  fever,  I  know  it  to  be  very 
easily  managed,  to  come  within  the  skill  of  any  intelligent 
nurse  or  attendant ;  and  that  by  its  means  the  temperature 
can  be  reduced  to  any  desired  point  and  maintained 
there.  The  apparatus  is  simple,  it  requires  but  a  small 
quantity  of  water,  it  involves  no  movement  of  the  pa- 
tient, and  occasions  no  shock  whatever.  I  therefore  be- 
lieve it  to  be  the  best  means  available  in  all  cases  of 
fever  where  artificial  reduction  of  the  temperature  is  de- 
sirable. This  method  was  adopted  very  successfully  by 
Dr.  Thomas,  for  peritonitis  following  ovariotomy,  in 
1876. 

Next  in  point  of  efficiency,  for  the  same  purpose,  I  would 
class  the  wet  pack,  by  which  I  mean  a  folded  sheet, 
wrung  out  of  tepid  or  cool  water,  and  wrapped  quickly 
around  the  patient's  body.  In  this  case  cooling  takes 
place  partly  as  a  result  of  evaporation.  If  the. attend- 
ants are  industrious  much  may  be  accomplished  by  the 
use  of  towels  wrung  out  of  cold  water  placed  upon  the 
body  and  limbs,  and  frequently  changed.  Least  useful 
of  all,  though  very  grateful  to  the  patient,  is  sponging 
with  cold  water.  If  done  often  enough  some  heat  is 
abstracted,  and  if  alcohol  is  used  with  the  water  evapora- 
tion aids  in  cooling. 

Where  it  is  necessary  to  effect  a  local  reduction  of 
temperature,  there  are  better  means  than  the  fever-cot. 
In  threatening  peritonitis  after  laparotomy,  for  instance, 
the  use  of  a  coil  of  lead  or  rubber  tubing,  through  which 
water  of  any  temperature  may  be  contmuously  passed, 
affords  a  perfectly  simple  and  efficient  means  of  accom- 
plishing the  purpose  desired. 

M.  Galante,  of  Paris,  in  1852,  devised  a  rubber  ap- 
paratus for  continuous  irrigation  of  the  eye.  Dr.  Petit- 
gand,  of  Paris,  had  manufactured  for  him  an  apparatus 
of  rubber  tubing  for  this  purpose  in  1859  >  *"^  ^^  ^^^^ 
he  published  a  description  of  a  head-cap  made  of  rubber 
tubing  for  the  use  of  cold  water,  and  a  sachet^  a  flat  coil 
of  rubber  tubing  precisely  similar  to  the  abdominal  coil 
now  in  use.  In  1879  ^'*'  Dumontpallier  published  a  de- 
scription of  a  series  of  tubular  covers  and  mattresses,  by 
the  use  of  which,  according  to  experiment,  he  claimed  to 
be  able  to  accomplish  much  iwore  rapid  and  uniform  re- 
frigeration in  typhoid,  varioloid,  and  other  fevers,  than 
could  be  accomplished  by  the  cold  baths  of  Brand. 

The  use  of  the  head  coil  of  lead  or  rubber  is  now  very 
general ;  and  the  abdominal  coil  is  likewise  becoming 
popular.  Nothing  can  be  simpler  or  less  disturbing  to 
the  patient  than  the  use  of  the  abdominal  coil,  and  in 
incipient  peritonitis  nothing  that  I  am  aware  of  is  so 


efficient.  The  application  of  the  rubber  coil  to  this 
particular  class  of  cases  was  suggested  by  Dr.  A.  B. 
Townsend,  in  the  Woman's  Hospital,  in  i88t.  The  coil 
is  applied  directly  to  the  skin,  or  a  thin  towel  is  inter- 
posed.  A  bandage  is  then  placed  around  the  body  to 
keep  the  coil  in  place ;  a  pail  of  water,  containing  a 
lump  of  ice,  stands  on  a  table  near  the  head  of  the  bed, 
and  a  pail  under  the  bed  receives  the  water  as  it  passes 
through.  At  the  latter  extremity,  where  the  water  es- 
capes, there  is  a  stop-cock  by  which  the  flow  may  be 
nicely  regulated  or  entirely  stopped,  as  may  be  rendered 
necessary  by  the  temperature  of  the  patient,  as  shown  by 
a  thermometer  placed  in  the  axilla  from  time  to  time. 
Unless  the  apparatus  should  be  irksome  to  the  patient, 
which  is  seldom  the  case,  it  is  not  necessary  to  remove  it 
as  long  as  there  is  any  likelihood  that  it  may  be  required. 
By  simply  opening  the  stop-cock  the  flow  of  water  begins, 
and  the  cooling  process  may  be  stopped  or  resumed  with- 
out waking  a  sleeping  patient. 

I  have  used  in  the  manner  just  described  both  the 
rubber  coil  and  the  coil  of  fine  leaden  tube  known  as 
Leiter's  coil.  The  latter  have  not  been  generally  in  the 
market,  or  I  think  they  would  have  taken  the  place  of 
the  rubber  in  many  cases.  They  are  not  so  heavy,  when 
full  of  water,  as  the  rubber  coil ;  they  are  not  liable  to 
become  dirty,  and  have  not  the  unpleasant  odor  of  rub- 
ber. They  are  more  durable  and  less  expensive.  They 
are  not  more  liable  to  become  clogged  with  dirt,  if  the 
precaution  is  taken  to  envelope  the  receiving  end  of  the 
tube  in  a  piece  of  gauze  or  coarse  muslin,  which  should 
be  done  in  all  cases.  With  this  precaution,  and  one 
nurse  of  ordinary  intelligence,  I  have  sometimes  kept 
the  leaden  apparatus  in  use  for  three  days  and  nights 
without  a  moment's  interruption.  One  advantage  of  the 
metal  coil  is  that  it  requires  less  water,  and  that  it  is  sel- 
dom necessary  to  use  ice.  Being  a  much  better  con- 
ductor than  the  rubber,  the  use  of  water  at  a  temperature 
of  45®  or  50°  is  quite  sufficient.  I  consider  these  appli- 
ances of  the  greatest  possible  value  where  inflammation  is 
threatened,  and  most  important  means  of  limiting  in- 
flammation when  it  has  developed.  In  case  of  bad 
operations,  where  there  is  every  reason  to  expect  peri- 
tonitis, I  have  the  coil  placed  upon  the  patient  im- 
mediately after  she  is  put  to  bed,  so  that  it  may  be  readjr 
for  use  at  any  moment.  In  ordinary  cases  I  wait  until 
the  temperature  rises  above  100°  in  the  axilla. 

In  the  method  spoken  of  the  object  of  course  is  to 
reduce  bodily  temperature  ;  but  cold  is  sometimes  used 
as  a  means  of  impressing  the  nervous  system.  Chap- 
man's ice-bags  act  on  this  principle,  and  have  been  found 
useful  in  many  nervous  disorders.  My  own  experience 
with  these  ice-bags  has  been  limited  chiefly  to  their  ap- 
plication in  cases  of  painful  and  scanty  menstruation. 
In  a  certain  class  of  cases  the  application,  for  half  an 
hour  at  a  time,  of  a  bag  of  crushed  ice  to  the  region  of 
the  lumbar  vertebrae  and  sacrum,  has  the  effect  of  pro- 
moting the  menstrual  flow.  Applied  to  the  dorsal  ver- 
tebrae, in  an  anaemic  patient  with  cold  extremities,  the 
tendency  of  the  ice-bag  is  to  equalize  the  circulation  and 
promote  warmth  throughout  the  whole  body. 

Friction  with  ice  is  employed  in  frost-bite.  The 
late  Dr.  Peace,  of  Philadelphia,  claimed  to  have  had  ex- 
cellent results,  in  a  cholera  epidemic  through  which  he 
passed  in  Europe,  from  vigorous  friction  of  the  limbs 
and  body  with  lumps  of  ice.  Where  it  is  necessary  to 
stimulate  the  nervous  system,  the  alternate  application 
to  the  spine  of  a  flat  brick  of  ice,  and  a  very  hot  iron, 
protected  by  flannel,  is  sometimes  very  eflfectual. 

I  shall  merely  allude  to  the  popular  and  time-honored 
belief  in  the  styptic  effects  of  cold ;  to  the  undoubted 
value  of  cold  for  the  relief  of  pain  in  bums ;  and  to  the 
efficacy  of  ice-cold  applications  in  the  causalgia  conse- 
quent on  injuries  of  the  nerves  from  gunshot  wounds. 

II.  Of  the  manifold  forms  in  which  heat  is  employed 
as  a  remedy  for  pain  and  disease,  I  shall  dwell  on  a  few 
only  of  the  most  striking,  at  the  risk,  as  in  what  I  have 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


399 


said  of  cold,  of  telling  a  thrice-told  tale.     For  the  arrest 
of  hemorrhage  a  high  degree  of  heat  has  been  long  in 
vogue.    The  hot  iron  has  held  its  place  as  a  styptic  prob- 
ably for  many  ce^ituries  ;  and  the  cautery  in  some  form 
is  still  constantly  employed  for  the  same  purpose.     The 
use  of  a  moderate  degree  of  heat  for  the  arrest  of  a  more 
general  hemorrhage  is  of  recent  origin.     To  Dr.  Em- 
met we  are  indebted  for  having  demonstrated  the  haemo- 
static properties  of  hot  water.     Where  ice  and    cold 
irater  were  formerly  used,  hot  water  is  now  found  to 
answer  a  better    purpose.      In   hemorrhage  from   the 
uterus  after  miscarriage,  or  after  removal  of  a  fibroid,  or 
from  any  other  cause,  injections  of  very  hot  water  at  the 
same  time  arrest  the  hemoithage  and  promote  contrac- 
tion of  that  organ.     This  is  one  of  the  many  applications 
of  heat  where  experience  has  placed  its  value  beyond  a 
doubt.    For  the  arrest  of  hemorrhage  from  an  exposed 
surface,  towels  dipped  in  very  hot  water  and  pressed 
firmly  on  the  bleeding  part  for  a  few  minutes  will  gener- 
ally act  much  more  promptly  and  permanently  than  cold 
water  used  in  the  same  way.  A  stream  of  very  hot  water 
thrown  with  a  syringe  into  any  bleeding  cavity,  if  there 
are  no  vessels  of  large  size,  will  generally  prevent  further 
flow  of  blood.     The  remarkably  good  e^ect  of  hot  water 
for  this  parpose,  during  and  after  operations,  may  be 
witnessed  every  day  in  many  of  our  hospitals.  One  great 
advantage,  if  there  were  no  other,  in  favor  of  the  use  of 
hot  water  for  exposed  surfaces,  or  for  the  uterine  cavity, 
is  that  the  process  of  boiling  is  purifying,  and  one  of  the 
most  reliable  means  of  destroying  organic  matter,  bacteria, 
or  other  minute  or^nisms  which  are  believed  to  play  so 
destructive  a  part  in  the  human  body.     A  higher  tem- 
perature than  that  of  boiling  water  has  been  proven  to 
destroy  some  germs  which  escape  simple  boiling.     For 
that  reason  I  always,  if  practicable,  employ  for  anti- 
septic solutions  and  for  surgical  purposes  water  from 
the  boiler  of  a  steam-engine,  which  has  usually  been 
heated  to  about  250^ 

The  beneficial  effects  of  vaginal  injections  of  hot  water 
are  now  generally  appreciated,  and  form  an  important 
part  of  every-day  gynecological  treatment  So  much  de- 
pends upon  the  manner  in  which  these  injections  are 
given,  that  I  will  venture  to  describe  the  method  I  con- 
sider the  best  The  patient  should  lie  flat  upon  a  bed 
or  sofa,  with  the  hips  raised  upon  a  broad  bed-pan,  ca- 
pable of  holding  four  or  five  quarts  of  water.  With  a 
Davidson's  syringe,  having  a  hard-rubber  nozzle  not  per- 
forated at  the  extremity,  a  stream  of  water  as  hot  as  can 
be  borne,  fi-om  100°  to  110*',  should  be  gently  thrown 
into  the  vagina  for  ten  or  fifteen  minutes,  or  until  three 
or  four  quarts  of  water  have  been  used.  The  David- 
son's syringe  is  better  than  the  fountain ;  a  bed-pan  with- 
out pipes  or  openings  or  stop-cocks  is  better  than  a  more 
complicated  apparatus.  It  is  difficult  to  keep  the  sim- 
plest vessel  of  the  kind  clean,  and  almost  impossible 
some  of  the  more  complicated  ones. 

The  effect  of  injections  given  thus  night  and  morning 
is  often  quite  surprising.  The  hot,  swollen,  congested 
mucous  membrane  or  the  vagina  assumes  a  normal  ap- 
pearance, the  offensive  discharge  ceases,  the  extreme 
tenderness  disappears,  the  engorged  cervix  softens  and 
diminishes  in  size,  there  is  a  marked  general  improve- 
ment without  any  medication  whatever,  and  the  patient 
has  made  a  great  step  toward  getting  well.  I  make  a 
rule  of  questioning  a  patient  in  detail  as  to  whether  she 
has  taken  her  injection  thoroughly.  A  pint  or  two  of 
lukewarm  water  feebly  thrown  into  the  vagina,  while  the 
patient  is  sitting  over  a  basin  or  other  vessel,  is  often  con- 
sidered sufficient  and  expected  to  yield  good  results  ;  but 
such  a  use  of  hot  water  for  this  purpose  resembles  the 
proper  injection  only  "  as  the  mist  resembles  the  rain," 
and  leads  only  to  disappointment.  In  pelvic  cellulitis  the 
persistent  use  of  hot  water  hastens  the  absorption  of  the 
plastic  exudation  and  shortens  the  duration  of  the  disease. 
One  of  the  applications  of  heat  that  may  appear  para- 
doxical, in  view  of  what  has  been  said  of  refrigeration  in 


peritonitis,  is  the  very  common  custom  of  covering  the 
abdomen  with  hot  poultices  for  the  relief  of  the  same  dis- 
ease. There  is  really  nothing  antagonistic  in  this.  The 
object  of  the  hot  application  is  not  to  augment  the  heat 
of  the  parts,  for  there  is  already  too  much  heat  and  con- 
gestion, but  what  the  poultices  and  hot  fomentations  do 
is  to  stimulate  the-  capillary  circulation  and  that  of  the 
underlying  lymphatics,  and  thus  relieve  the  engorgement 
of  organs  more  remote.  Such  applications  are  grateful 
to  the  patient,  and  that  they  often  do  much  good  there 
can  be  no  doubt.  I  think  that  warm  applications  are 
useful,  chiefly  in  the  forms  of  peritonitis  that  develop 
rather  insidiously,  with  pain  over  a  large  area.  Where 
the  disease  is  local,  and  especially  of  traumatic  origin,  I 
should  prefer  cooling  measures  from  the  beginning.  There 
is  nothing  at  all  inconsistent  in  the  use  of  both  hot  and 
cold  applications  at  different  stages  of  the  same^disease, 
and  in  the  same  case. 

It  would  carry  me  beyond  my  limits  even  to  enumer- 
ate all  the  familiar  applications  of  heat  in  therapeutics. 
The  value  as  a  counter-irritant  of  Paquelin's  cautery, 
used  at  a  white  heat  and  brushed  lightly  over  the  sur- 
face, is  generally  acknowledged.  The  application  of 
heat  over  the  region  of  the  heart  as  a  stimulant  in 
threatening  collapse,  is  often  found  of  value,  and 
I  have  utilized  the  rubber  coil  for  that  purpose;  the 
medicinal  use  of  hot  water  as  a  beverage  reminds  us 
that  there  is  fashion  in  everything.  More  than  one  hun- 
dred and  fifty  years  ago  Le  Sage,  in  his  immortal  "  Dr. 
Sagrado,"  ridiculed  the  routine  use  of  hot  water  and 
bleeding.  The  hot  water  has  come  back  to  us ;  the  bleed- 
ing, as  its  adjunct,  may  follow. 

In  conclusion,  I  would  suggest  that  as  we  have  in  heat 
and  cold  agents  powerful  enough  to  destroy  life,  and  un- 
c^er  proper  control  capable  of  modifying  all  its  functions, 
they  should  always  be  prescribed  with  a  definite  object 
and  used  in  a  definite  manner.  As  their  use  is  often 
intrusted  to  those  who  know  nothing  of  the  principles 
on  which  they  act,  and  who  are  influenced  by  custom  or 
prejudice,  the  physician  should  take  suitable  opportuni- 
ties of  imparting  some  general  information  to  his  patients 
as  to  the  most  rational  means  of  employing  remedies 
that,  however  or  by  whomsoever  prescribed,  will  always 
be  considered  the  property  of  the  household,  and  within 
the  province  of  domestic  practice. 


A  RARE  FORM  OF  LOBAR  PNEUMONIA- 
TUBERCULOUS  CROUPOUS  LOBAR  PNEU- 
MONIA. 

By  FRANCIS  P.  KINNICUTT,  M.D., 

PHYSICIAN  TO  ST   LUKB^S  HOSPITAL,   NEW  YORK. 

F.  H ,  male,  aged  thirty-three,  single,  native  of  Eng- 
land, was  admitted  to  my  service  in  St.  Luke's  Hospital 
March  6,  1884.  Family  history  not  obtainable.  The  pa- 
tient states  that  he  has  never  suffered  from  any  ])ulmonary 
affection.  Eighteen  months  ago  he  was  injured  in  a  rail- 
way accident,  and  has  been  troubled  since  that  time  with 
a  continuous  •*  to  and-fro  movement  of  his  head,"  which 
he  has  been  told  ceases  during  sleep.  During  this  period 
he  has  lost  flesh.  He  has  had  no  cough  or  hemorrhage, 
and  was  apparently  in  good  health  until  three  days  before 
admission  to  the  hospital,  when  he  had  several  sharp  chills, 
followed  by  cough  and  a  thickish  expectoration  and  ap- 
parently fever.  On  admission  to  hospital  patient  was 
fairly  well  nourished;  temperature,  104°;  pulse,  100; 
respirations,  38.  There  was  cough ;  the  sputa  were  viscid, 
but  not  rusty.  There  was  a  constant  rhythmical  to-and- 
fro  movement  of  the  head,  which  ceased  during  sleep. 
Examination  of  the  chest  showed  dulness,  with  feeble 
respiratory  murmur  and  abundant  fine  inspiratory  crepita- 
tion over  the  infra-clavicular  region  and  upper  portion  of 
the  mammary  of  the  right  side.  The  urine  was  acid, 
specific  gravity  1.028,  and  was  free  from  albumen  and 
suffar.  The  chest  was  very  carefully  examined  by  me 
daily.     The  physical  signs  of  consolidation  of  the  entire 


400 


THE  MEDICAL  RECORD. 


[October  ii,  1884, 


upper  lobe  of  the  right  lung  (marked  dulness,  bronchial 
respiration,  and  bronchophony)  rapidly  supervened ;  there 
was  continuous  pyrexia ;  the  pulse-respiration  ratio  of 
one  to  a  little  less  than  three  was  maintained.  Until  the 
eighth  or  ninth  day  of  the  patient's  illness  the  clinical 
course  of  the  disease  in  all  respects  corresponded  with  an 
ordinary  attack  of  croupous  lobar  pfieumonia,  and  was 
so  regarded  by  me.  Resolution,  however,  did  not  occur 
at  the  customary  period  ;  there  was,  on  the  contrary,  from 
the  ninth  day  after  admission  to  hospital  until  death,  a 
gradually  increasing  pyrexia,  pulse,  and  respiratory  rate. 
Examination  of  the  chest,  moreover,  revealed  a  very 
rapidly  developing  disintegration  of  lung  tissue  at  differ- 
ent points  in  the  affected  area.  On  the  thirteenth  day 
there  were  the  physical  signs  of  a  small  cavity  in  the 
upper  portion  of  the  consolidated  lobe,  corresponding  to 
the  site  at  which  the  largest  excavation  was  found  after 
death 

During  the  last  days  of  life  slight  haemoptyses  occurred, 
and  there  was  effusion  into  the  right  pleural  cavity.  A 
similar  case  had  never  before  been  observed  by  me,  but 
from  the  clinical  cpurse  of  the  disease  I  finally  was  led 
to  believe,  and  expressed  the  opinion,  that  the  morbid 
process  might  well  be  expressed  by  the  term  tuberculous 
croupous  lobai*  pneumonia.  The  patient  died  on  the 
sixteenth  day  after  admission  to  hospital,  on  the  nine- 
teenth from  the  first  symptoms  of  acute  illness,  with  the 
signs  of  general  pulmonary  oedema  and  heart-failure.* 

The  autopsy  was  made  by  Dr.  Ferguson  in  my  pres- 
ence. The  morbid  changes  were  confined  to  the  brain, 
the  spleen,  and  the  lungs.  There  was  marked  atrophy 
of  the  convolutions  over  the  vertex.  The  spleen  was 
large  and  soft.  The  right  pleural  cavity  contained  about 
forty  ounces  of  semi-purulent  fluid  ;  the  pulmonary  pleura 
was  covered  with  recent  fibrin.  The  left  lung  was  in- 
tensely congested  and  oedematous  ;  the  entire  upper  lobe 
of  the  right  lung  was  hepatized.  On  section  the  solidified 
portion  appeared  dry,  smooth,  and  grayish  in  color  and 
homogeneous  in  consistency  throughout.  The  cut  sur- 
face did  not  present  the  granular  appearance  of  gray 
hepatization,  and  the  edge  of  the  knife  carried  over  it 
did  not  remove  the  alveolar  contents.  Numerous  miliary 
tubercles  could  be  distinguished  at  the  periphery  of  the 
consolidation.  The  middle  lobe  and  the  upper  portion 
of  the  lower  lobe  contained  numerous  miliary  tubercles. 
There  were  several  small  cavities  in  the  consolidated 
portion,  varying  in  size  from  that  of  a  pea  to  a  walnut, 
partially  filled  with  material  not  completely  disintegrated. 
In  sections,  the  alveolar  walls  were  seen  to  be  slightly 
thickened  and  the  alveoli  to  be  distended  with  pus,  a 
small  amount  of  fibrin,  granular  material  and  epithelial 
cells  similar  in  appearance  to  those  lining  the  alveolar 
walls  in  the  normal  state.  The  alveolar  contents  in  places 
had  undergone  cheesy  degeneration.  These  areas  of 
cheesy  degeneration,  which  were  numerous  through- 
out the  consolidated  portion  of  the  lung,  were  limited  by 
zones  of  small  round  cells  of  inflammatory  origin.  In 
some  of  the  caseous  areas  the  alveolar  septa  were  still 
preserved,  but  very  generally  they  had  disappeared  in 
these  areas,  a  fusion  of  many  alveoli  having  occurred. 
In  the  neighborhood  of  the  solidified  portion  there  were 
numerous  miliary  tubercles  and  tuberculous  masses  with 
broken-down  centres  ;  in  both,  giant  cells  were  well  de- 
veloped and  abundant.  In  the  interstitial  tissue  of  the 
lung  surrounding  the  tuberculous  masses  numerous  small 
cells,  both  round  and  fusiform,  were  seen.  Tubercles 
were  not  found  in  the  other  organs. 

The  pathological  changes  above  described  would  seem 
to  justify  the  application  of  the  term  tuberculous  croup- 
ous lobar  pneumonia  to  the  morbid  process.  An  ap- 
parently similar  morbid  process  has  been  described  by 
pathologists,  but  I  have  been  unable  to  find  any  clinical 
record  of  such  cases,  with  the  exception  of  a  general 

'  The  sputa  were  not  examined  until  the  fourteenth  day  ;  two  specimens  were 
then  examined,  but  tubercle  bacilli  were  not  found.  On  the  fifteenth  and  sixteenth 
^ays  the  spuu  were  m  scanty  that  specimens  could  not  be  obtained  for  examina- 
tion. 


reference  to  them  by  Rindfleisch  and  a  very  brief  report 
of  two  cases  communicated  to  the  French  Academy  of 
Medicine,  December  4,  1883,  by  Professor  Sde,  under 
the  title  of  "  Phthisis  in  the  Form  of  Lobar  Pneumonia." 
I  give  the  latter  as  reported  in  Le  Progris  MidiccUoi 
December  8,  1883 : 

Case  I. — A  young  man,  nineteen  years  of  age,  a  hos- 
pital patient,  was  seized  on  September  13th  wifii  a  well- 
marked  attack  of  simple  pneumonia,  which  involved  the 
upper  two-thirds  of  the  right  lung.  At  the  end  of  the 
ninth  day,  defervescence  not  having  taken  place,  the  sputa 
were  examined  and  bacilli  in  great  numbers  discovered. 
Early  in  October  all  the  signs  of  an  exca^vation  became 
apparent* 

Case  II. — A  patient  in  the  same  hospital  ward  pre- 
sented all  the  signs  of  a  simple  pneumonia,  which,  how- 
ever, did  not  undergo  resolution.  The  sputa  were  twice 
examined,  revealing  only  ordinary  microbes  in  great  num- 
bers. A  third  examination  established  the  presence  of  a 
small  number  of  tubercle  bacilli.  Shortly  afterward  the 
local  signs  confirmed  the  diagnosis. 

Rindfleisch,'  under  the  head  of  ''Cheesy  Lobar  Pneu- 
monia," describes  a  form  of  desquamative  pneumonia 
(Buhl)  which  occurs  as  a  diffuse  inflammation  of  an  en- 
tire lobe  aflfected  by  tuberculosis.  "  Usually  the  earlier 
stages  of  the  disease  have  already  passed  by  at  the  apex 
of  the  lung  and  cavities  have  formed,  when  a  sudden  at- 
tack of  cheesy  pneumonia  occurs  and  involves  at  once 
the  rest  of  the  upper  lobe.  This  usually  happens  with 
an  acute  exacerbation  of  all  the  clinical  syniptoms,  the 
fever,  dyspnoea,  and  rapid  pulse,  so  that  the  impression  is 
given  of  an  intercurrent  croupous  lobar  pneumonia, 
and  the  first  glance  at  the  lungs  might  seem  to  confirm 
this  opinion,  for,  as  Virchow  luis  shown,  there  are  veiy 
often  in  the  alveoli  plugs  of  real  fibrinous  exudation,  so 
that  the  section  of  the  lung  looks  granular.  But  the  dis- 
tinction lies  in  the  infiltration  of  the  alveolar  walls,  a  con- 
dition very  slightly  developed  in  croupous  pneumonia," 

I  prefer  to  regard  the  morbid  process  observed  in  my 
own  case,  and  which  has  been  carefiilly  described,  as  an  ex- 
ample of  an  intercurrent  croupous  pneumonia^  from  the 
presence  in  the  alveoli  of  the  usual  products  of  such  an 
inflammation — /.^.,  pus  and  fibrin — which  Buhl "  insists 
are  never  present  in  the  desquamative  pneumonia  first 
described  by  him.  The  implication  of  the  alveolar  walls 
and  the  presence  of  only  a  small  amount  of  fibrin  among 
the  alveolar  contents  I  shall  again  refer  to. 

The  question  of  the  probable  period  of  the  develop- 
ment of  tubercles  in  the  above  case  is  certainly  an  open 
one.  Personally,  I  am  inclined  to  believe  that  a  slight 
deposition  of  tubercles  occurred  at  some  time  previous  to 
the  beginning  of  the  patient's  acute  illness,  but  that  little 
or  no  constitutional  disturbance  was  produced  thereby. 
The  history  of  the  patient,  the  clinical  course  of  the 
acute  disease  as  observed  by  me,  and  finally  the  post- 
mortem appearances,  would  seem  to  justify  the  opinion 
that  on  the  date  of  the  recorded  chills  a  true  croupous 
pneumonia  was  developed  in  the  tuberculous  lobe  of  the 
lung  ;  that  the  pneumonic  process  furnished  suitable  soil 
for  a  very  rapid  and  abundant  development  of  the  bacilh 
tuberculosis  ;  that  there  was  a  consequent  equally  rapid 
degeneration  of  the  tubercles  of  older  date,  and  also  of 
the  pneumonic  products.  The  objection  to  considering 
the  pneumonic  process  a  croupous  one  on  account  of  the 
serious  involvement  of  the  alveolar  walls,  may  be  met 
by  the  argument  that  such  an  implication  is  believed  by 
many  pathologists  to  occur  in  cases  of  croupous  pneu- 
monia where  resolution  is  delayed.  The  presence  of 
only  a  small  amount  of  fibrin  among  the  alveolar  con- 
tents may  be  explained  in  a  similar  manner ;  degener- 
ative changes  are  to  be  expected  where  life  is  prolonged 
to  the  nineteenth  day  firom  the  beginning  of  the 
attack. 

^  Cyclopaedia  of  Medicine^  von  Zienuien,  voL  v.,  p>  673. 
■  Buhl :  Lungen  Rntzflndung,  Tuberkulose  und  Schwindfilchdj;,  p.  so-    M"°" 
chen,  187a 


October  II,  1884.] 


THE  MEDICAL  RECORD. 


401 


MORPHIA  IN  CARDIAC  DISEASE. 
By  BENJAMIN  EDSON,  M.D., 

BSOOKLYH,  N.  Y. 

The  following  case  seems  to  have  some  bearing  upon  the 
Qse  of  morphia  in  one  form  of  disease  of  the  heart. 

C,  R ,  fifty-six  years  of  age,  Scotchman,  merchant, 

called  at  my  office  early  in  November,  1883,  complain- 
ing of  a  troublesome  cough  and  shortness  of  breath  on 
exertion.  He  attributed  his  trouble  to  "  catching  cold  " 
^m  exposure.  As  he  was  in  great  haste  I  prescribed  a 
cough  mixture  without  making  thorough  investigation. 

A  few  days  later  he  called  again.  His  cough  was  no 
better,  and  his  respiration  so  much  more  difficult  that  he 
could  not  lie  down  to  sleep.  When  I  proposed  an  exami- 
nation, he  slapped  his  hand  upon  his  chest,  saying : 
*< There  is  nothing  the  matter  with  me  here,  sir  :  I'm  as 
sound  as  a  dollar."  I  found,  however,  that  he  had  mi- 
tral regurgitation  with  marked  dilatation  of  the  heart. 
The  cause  of  the  cough  and  dyspnoea  was  but  too  appar- 
ent The  kidneys  were  not  affected,  and  as  yet  there 
was  no  oedema.  A  few  days  later  the  legs  began  to 
swell.  I  advised  him  to  keep  strictly  quiet,  and  at  the 
same  time  put  him  upon  such  treatment  as  seemed  best 
calcolated  to  give  relief.  I  found  it  difficult  to  convince 
him  of  the  grave  nature  of  his  disease,  and  being  of  a 
nervous^  active  temperament,  he  considered  it  a  great 
hardship  not  to  be  permitted  to  attend  to  his  daily  busi- 
ness in  New  York.  Finally  I  persuaded  him  to  consult 
Dr.  Armor,  who  confirmed  my  diagnosis  and  approved 
the  treatment,  which  ''must  be  palliative  and  on  general 
pfindplea." 

For  the  next  two  or  three  weeks  he  continued  fairly 
comfortable,  the  oedema  moderate,  but  he  was  able  to  sleep 
only  as  he  reclined  in  his  chair.  He  was  very  irritable,  and 
urgently  called  for  something  that  would  enable  him  to 
sleep  in  bed,  I  did  not  feel  warranted  in  granting  this 
request,  but  still  he  insisted  that  he  must  have  some  good 
sleep.  Finally,  through  the  persuasion  of  a  relative,  he 
was  induced  to  call  in  a  distinguished  homoeopathic 
physician,  who  acceded  to  his  request  and  gave  him 
sufficient  morphia  to  enable  him  to  sleep  several  hours 
in  bed.  But  on  waking  and  attempting  to  rise  he  was 
seized  with  dyspnoea  that  nearly  terminated  his  life. 
By  vigorous  efforts  on  the  part  of  his  attendants  he 
erentnally  rallied  somewhat,  but  soon  after  he  suddenly 
fell  back  and  expired. 

I  have  considered  that  death  in  this  case  was  due  to 
the  morphia  used.  It  may  have  been  only  indirectly  the 
cause,  by  permitting  the  patient  to  assume  the  recumbent 
position,  rising  from  which  produced  over-distention  or 
overwhelming  of  the  weakened  heart-structure.  Morphia 
may  have  contributed  to  the  paralysis.  Bartholow  (''  Ma- 
teria* Medica,"  5th  ed.,  p.  524)  says  of  lethal  doses  of 
morphia,  that  "  in  some  instances  very  sudden  death  en- 
sues from  paralysis  of  the  heart"  How  large  the  dose 
required  to  produce  this  untoward  result  obviously  de- 
pends much  upon  the  condition  of  the  heart  What  in 
health  might  be  but  a  medicinal  dose  of  morphia,  in  case 
of  dilatation,  with  muscular  walls  greatly  weakened  and 
nerve-distribution  disturbed,  might  readily  prove  to  be  a 
lethal  or  paralyzing  dose.  Thus  in  this  case  it  is  not 
improbable  that  both  these  factors  conduced  to  the  sud- 
den death  of  the  patient 

This  man  had  never  had  rheumatism,  and  previous  to 
this  illness  there  had  never  been  any  suspicion  of  cardiac 
trouble. 

In  looking  back  over  this  case  there  arises  a  question 
which  leads  to  speculation,  and  which  may  not  be  wholly 
devoid  of  interest.  In  the  summer  of  1880,  through 
some  business  complications,  this  man  had  a  period  of 
very  great  mental  depression.  It  took  the  form  of 
marked  pathophobia.  He  was  fearful  that  he  would 
drop  down  dead,  and  that  his  body  would  be  unrecog- 
nized and  sent  to  the  morgue,  so  he  was  very  particular 
to  keep  in  every  pocket  papers  bearing  his  name  and 


address,  with  minute  directions  as  to  what  should  be 
done  in  case  of  the  event  he  so  much  feared.  Scores  of 
times  daily  he  took  out  these  papers  and  examined  them 
to  reassure  himself  that,  if  he  did  drop  dead,  his  body 
could  be  properly  identified.  On  one  occasion,  being 
up-town  in  New  York,  the  "  feeling "  came  over  him 
that  he  never  could  get  back  to  his  store  alive.  His  evil 
genius  told  hhn  that  he  must  not  ride,  and  he  had  not  the 
power  to  walk.  In  this  dilemma  it  was  finally  revealed 
to  him  that  he  could  perchance  run  back.  This  he  did, 
by  short  runs  between  lamp-posts  and  awning-posts,  to 
each  of  which  he  would  cling  while  screwing  up  courage 
to  make  a  bold  run  for  the  next  goal.  In  this  way  he 
finally  reached  his  store,  out  of  breath  and  reeking  with 
perspiration. 

While  narrating  these  and  many  other  freaks  of  his- 
malady  equally  ridiculous,  he  remarked,  **  You  may  laugh 
at  them  ;  I  do  now ;  but  when  the  incubus  is  upon  me- 
I  am  a  coward,  a  victim  of  my  fancies."  After  a  few 
weeks  his  business  troubles  passed  away,  and  with  them 
his  morbid  fear  of  death. 

There  is  a  possibility — indeed,  is  there  not  a  strong 
probability? — that  at  this  time  there  was  actual  heart- 
trouble.  If  so,  whether  it  stood  in  the  relation  of  cause  or 
of  consequence  is  of  course  mere  speculation.  Is  patho- 
phobia, with  the  kindred  affections,  agoraphobia,  etc., 
simply  a  functional  derangement — a  neurosis—or  may  it 
not  be  associated  with  and  possibly  dependent  upon 
actual  pathological  conditions  ? 

§lje}j0rts  of  ^ospitalB. 


COOK    COUNTY    HOSPITAL,    CHICAGO,    ILL. 

Case  of  Congenital  Diaphragmatic  Hernia. 

Reported  by  M.  L.  HARRIS,  M.D.,  House  Physician. 

E.  C ,  male,  aged  thirty-four,  laborer,  was  received 

into  the  hospital  November  15,  1883,  under  the  care  of 
Dr.  F.  Henrotin,  attending  physician. 

On  admission  the  patient  was  much  prostrated  and 
suffered  from  intense  dyspnoea ;  hence  no  accurate  ac- 
count of  his  history  was  elicited.  He  said  that  he  had 
usually  enjoyed  good  health,  and  that  this  was  his  first 
acute  illness.  The  case  was  found  to  be  one  of  acute 
croupous  pneumonia  affecting  the  lower  lobe  of  the  right 
lung  and  complicated  with  an  acute  pleurisy  of  the  same 
side.  November  17th  the  patient  died  suddenly  and  un- 
expectedly. 

The  autopsy  was  held  forty-eight  hours  after  death  by 
Dr.  W.  T.  Belfield,  pathologist  to  the  hospital. 

Body  of  spare  build,  the  abdomen  markedly  depressed. 
After  the  usual  incision  from  chin  to  pubes  and  removal 
of  the  sternum,  the  appearance  represented  in  Fig.  ^ 
was  exhibited.  The  heart  was  in  about  the  usual  posi- 
tion, the  apex  a  trifle  nearer  the  sternum  than  normal. 
The  right  pleural  cavity  contained  some  recently  coagu- 
lated lymph.  The  inferior  and  middle  lobes  of  the  right 
lung  exhibited  gray  hepatization ;  the  lower  portion  of 
the  upper  lobe  showed  red  hepatization  ;  the  upper  por- 
tion of  this  lobe  was  quite  oedematous. 

The  left  pleural  cavity  contained,  besides  the  left  lung, 
the  stomach,  nearly  all  of  the  small  intestine,  part  of  the 
colon,  and  half  of  the  pancreas.  The  lung,  eight  inches 
in  length,  one  to  two  inches  in  thickness,  and  two  to 
three  inches  in  breadth,  was  crowded  into  the  anterior 
and  upper  portion  of  the  left  chest,  resting  against  the 
mediastinum.  It  appeared  to  consist  chiefly  of  the  upper 
lobe,  which,  with  the  exception  of  a  few  cheesy  nodules 
in  the  apex  and  some  slight  oedema,  was  fairly  normal, 
crepitating  well  and  floatmg  upon  water.  The  inferior 
lobe  was  crowded  into  a  small  firm  mass  which  contained 
no  air  and  sank  in  water. 

The  abdominal  cavity   vas  shallow,  containing  only 


402 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


the  liver,  kidneys,  spleen,  a  small  portion  of  the  ileum 
and  ascending  colon,  and  the  descending  colon.  The 
liver  was  slightly  enlarged  and  fatty;  the  anterior  border 
of  the  right  lobe  extended  downward  four  fingers'- 
breadth  below  the  margin  of  the  ribs,  its  deep  position 
being  due  not  to  an  increase  in  size  but  to  a  tipping  for- 
ward and  downward  of  the  organ.  The  kidneys  and 
spleen  occupied  their  normal  positions  respectively  and 
appeared  healthy. 


Fig.  1.— I,  Left  lun^  ;  2,  convolution  of  small  intestine ;  3,  heart  in  sac ;  4.  Iber : 
«,  q>leen ;  6,  descending  colon ;  ?»  lower  end  of  ileum ;  8,  ooecum ;  9,  siinnoid 
flexure ;  10.  bladder 

-  The  diaphragm  presented  a  single  large  opening  occu- 
pying its  central  and  posterior  portion,  through  which 
the  various  organs — inferior  vena  cava,  aorta,  thoracic 
ducty  portal  vein,  small  and  large  intestine,  pancreas, 
superior  mesenteric  artery,  etc. — passed  to  or  from  the 
thorax.     This  foramen  was  large  enough  to  permit  the 


FiC  a.— 1,  CEsophagus;  %,   stomach;  3,  pylorus;  4,  cardia;  s, 

(dotted  line) ;  6,  pancreas  (dotted  line) ;  7,  spleen;  8,  arch  of  aorta;  9,  pulmonary 
artery ;  10^  heart  (drawn  to  right) ;  ix,  descending  aorta ;  za,  diaphragm ;  13,  cut 
end  of  portal  vein ;  14,  kidney ;  15.  descending  colon ;  x6,  ileum ;  17,  ooecum : 
18,  sigmoid  flexure  ;  19,  bladder. 

passage  of  the  closed  fist.  The  left  border  of  the  right 
cms  arched  to  the  left,  forming  the  free  margin  of  the 
foramen  ;  this  was  round  and  smooth  and  attached  to 
the  head  of  the  twelfth  rib  and  to  the  base  of  the  trans- 
verse process  of  the  twelfth  dorsal  vertebra.  There  was 
no  left  cms.  The  course  and  relations  of  the  alimentary 
canal  are  shown  in  Fig.  2.     Here  the  lungs  and  liver  I 


have  been  removed,  the  heart  drawn  to  the  right  and  the 
small  intestine  to  the  left,  the  ribs  represented  by  the 
dotted  lines. 

The  oesophagus  passed  behind  the  arch  of  the  aorta, 
along  the  anterior  and  right  side  of  the  descending  aorta, 
until  it  reached  the  eighth  dorsal  vertebra,  ¥^ere  it 
passed  in  front  of  the  aorta,  suddenly  turned  vertically 
upward,  and  sSter  a  course  of  about  two  inches  entered 
the  cardiac  extremity  of  the  stomach.  The  stomach  it- 
self extended  from  this  point  upward  to  the  apex  of  the 
thoracic  cavity,  then  curved  forward  and  downward,  so 
that  the  greater  curvature  looked  backward  and  upward, 
the  lesser  forward  and  downward.  The  duodenum  com- 
menced opposite  the  third  intercostal  space  in  front, 
passed  down  through  the  opening  in  the  diaphragm  into 
the  abdomen,  making  a  loop  about  eight  inches  in  the 
abdominal  cavity,  in  which  lay  the  head  of  the  pancreas ; 
thence  it  passed  back  through  the  opening  into  the 
thorax.  The  remainder  of  the  small  intestine  lay  within 
the  thoracic  cavity,  with  the  exception  of  about  twelve 
inches  of  the  inferior  extremity  of  the  ileum,  which 
passed  through  the  opening  in  the  diaphragm  into  the 
abdomen  toward  the  right  iliac  region,  where  it  joined 
the  coecum,  the  latter  occupying  nearly  its  normal 
position. 

The  ascending  colon  passed  directly  into  the  thorax  in 
front  of  the  duodenum ;  the  transverse  extended  along 
the  left  side  of  the  stomach  and  entered  the  abdomen 
again  ;  the  descending  colon  occupied  nearly  its  normal 
position.  The  rectum  descended  along  the  centre  of  the 
sacrum. 

The  pancreas  lay  directly  in  the  opening,  half  within 
the  abdomen  and  half  within  the  thorax.  The  coeliac 
axis  and  mesenteric  arteries  were  given  off  at  their  usual 
site.  The  gastric  branch  of  the  former  and  the  superior 
mesenteric  passed  upward  into  the  thorax,  the  splenic 
and  hepatic  branches  directly  to  their  respective  organs. 
The  portal  vein  descended  through  the  opening  to  the 
liver.    The  genito-urinary  tract  was  normaL 


ST.  CATHERINE'S  HOSPITAL,  BROOKLYN,  N.  Y. 

Case  of  Rupture  of  the  Diaphragm. 

Reported  by  JAMES  L.  KORTRIGHT,  M.D.,  Cuxator. 

Simon  S ,  fifty-eight  years  of  age;  German.    Patient 

fell  or  sprang  from  the  top  of  a  three-story  building.  He 
alighted  upon  his  feet  and  immediately  fell  prone  with 
great  force.  He  died  three  minutes  after  admission,  and 
half  an  hour  after  the  receipt  of  the  injury.  At  the  au- 
topsy there  was  found  a  contusion  in  the  frontal  region 
without  fracture  of  the  skull  or  injury  to  the  brain ;  a 
compound  Colles'  fracture  at  left  wrist ;  a  simple  fracture 
at  lower  third  of  right  femur ;  a  simple  fracture  of  the 
neck  of  the  left  femur ;  fractures  of  the  costal  cartilages 
of  third  and  fourth  ribs  on  the  right  side,  and  of  the  fourth, 
fifth,  and  sixth  ribs  on  the  left  side.  There  was  a  large 
rent  three  inches  in  length  across  the  muscular  fibres  of 
the  left  side  of  the  diaphragm  half  an  inch  from  their 
insertion  into  the  central  tendon.  Through  this  rent 
there  was  a  hernia  of  the  entire  stomach  and  transverse 
colon  with  the  greater  omentum.  The  stomach  was  dis- 
tended with  food  and  contused  on  its  anterior  wall.  The 
heart  was  displaced  to  the  median  line,  and  stood  verti- 
cally. Has  any  one  ever  seen  a  similar  injury  or  knomi 
of  a  case  where  the  abdominal  viscera  were  driven  through 
the  diaphragm  ? 

A  Successful  Woman  I'hysician. — L' Union  Midi- 
cale  gives  an  account  of  the  career  of  a  Parisian  doctress 
who,  after  her  school  and  hospital  experience,  went  to 
Turkey,  and  after  many  adventures  was  made  physician 
to  a  prince's  harem,  on  a  salary  of  100,000  to  150,000 
francs  a  year.  This  was  "  the  bouquet  of  her  adventur- 
ous existence."  She  subsequently  lost  this  position  but 
made  amends  by  making  a  marriage  de  haute  convenanct. 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


403 


Removal  of  a  Foreign  Body  from  the  Knee. — M. 
Boadet  relates  the  case  of  a  child  who  inserted  a  threaded 
needle  into  the  knee  at  the  internal  border  of  the  patella. 
An  attempt  to  extract  the  needle  by  pulling  on  the  thread 
resulted  only  in  breaking  the  latter.  An  incision  was 
then  made,  and  although  the  needle  could  be  easily  felt 
in  the  tissues  it  could  not  be  removed.  It  was  finally 
proposed  to  place  the  child  in  the  same  position  it  oc- 
cupied when  the  object  was  introduced.  This  was  done 
and  the  needle  was  extracted  with  ease.  Ambroise  Par6 
practised  a  similar  manoeuvre  when  the  King  of  Navarre 
was  wounded  by  a  ball  in  the  shoulder  at  the  siege  of 
Rouen.  The  other  surgeons  having  failed  in  their  efforts 
to  extract  the  bullet,  Par6  advised  the  illustrious  patient 
to  assume  the  same  position  in  which  he  was  at  the  time 
of  receiving  the  wound.  He  did  so,  and  the  removal  of 
the  foreign  body  was  accomplished  with  facility. — Revue 
Midicale,  No.  32,  1884. 

Treatment  of  Ozcena. — The  following  is  the  formula 
employed  by  M.  Vidal  at  the  Hdpital  St.  Louis,  in  the 
treatment  of  ozoena  {Journal  de  Medecine  et  de  Chi- 
rurgie  PratiqueSy  August,  1884)  :  Solution  of  chloride  of 
zinc  (5  per  cent),  1  ounce;  boracic  acid,  15  grains; 
water,  28  ounces  ;  ammonia,  q.  s.  to  neutralize  the  fluid. 
A  little  of  this  solution  is  snuffed  up  into  the  nostrils 
several  times  a  day.  M.  Gorecki  employs  for  the  same 
purpose,  and  in  the  same  way,  a  warm  saturated  solution 
of  boracic  acid.  By  means  of  one  or  other  of  these  prep- 
arations the  fetid  odor  may  be  destroyed,  in  most  cases, 
within  a  few  days. 

Encephalic  Bellows  Murmur  in  Children. — ^This 
sound,  when  it  exists,  is  intermittent  and  isodironous  with 
the  cerebral  pulsations.  It  is  often  perceptible  over  the 
interior  fontanelle  only.  According  to  Dr.  Jurasq,  this 
phenomenon  is  of  no  diagnostic  value,  but  occurs  at  any 
time  between  the  third  month  and  the  sixth  year  of  life. 
The  sound  seems  to  be  produced  in  the  carotid  canal  or 
in  the  foramen  spinale.  These  foramina  vary  greatly  in 
diameter  in  children,  and  the  bruit  results  from  a  dispro- 
portion between  the  calibre  of  the  osseous  openings  and 
diat  of  the  internal  carotid  or  middle  meningeal  arteries 
which  traverse  them. — Revue  Afidicale^  August  30,  1884. 

CuTROPHOBiA. — By  this  terra  is  understood  a  disturb- 
ance of  the  cerebral  functions,  somewhat  similar  to 
agoraphobia.  The  subjects  of  this  affection  have  a  horror 
of  being  in  any  enclosed  place.  When  shut  up  in  a  room 
they  experience  a  sensation  of  heat  in  the  head,  the 
arteries  of  the  temples  beat  forcibly,  they  become  furious 
and  make  frantic  attempts  to  open  the  door  or  to  leap 
from  the  window.  Clitrophobia  may  exist  as  a  pure 
mononiania  unaccompanied  by  any  other  delirious  mani- 
festations, or  it  may  occur  in  connection  with  other 
psychological  disturbances.  It  is  a  rare  condition,  and 
the  prognosis  should,  in  every  case,  be  a  reserved  one. 
—Revue  Medicale^  No.  35,  1884. 

Inhalation  of  the  Vapor  of  Glycerine  for  Cough. 
—Professor  Trastor  employs  with  great  benefit  the  vapor 
of  glycerine  for  the  alleviation  of  a  fatiguing  or  painful 
cough.  A  couple  of  ounces  of  glycerine  are  put  in  a 
porcelain  dish  and  evaporated  over  an  alcohol  lamp.  A 
Urge  quantity  of  vapor  is  thus  given  off  which  is  inhaled 
with  great,  relief  by  patients,  especially  consumptives 
who  are  troubled  with  a  harassing  cough. — Revue  Midi- 
eale,  August  30,  1884. 

EccHVMOSis  OF  Nervous  Origin. — In  an  interesting 
paper  published  in  the  Revue  de  Mtdecine  of  August  10, 
1&84,  Dr.  Keller  relates  a  number  of  cases  observed  by 
him  of  ecchymosis  occurring,  without  the  intervention  of 
traumatism,  in  nervous  subjects.  He  came  to  the  con- 
clusion that,  as  in  similar  cases  stated  by  Straus  to  occur 
in  locomotor  ataxia,  the  ecchymoses  were  directly  depen- 


dent upon  the  abnormal  condition  of  the  nervous  system 
in  these  patients,  and  this  view  was  strengthened  by  the 
fact  that  the  spots  appeared  less  frequently  in  proportion 
as  improvement  occurred  in  the  nervous  condition.  The 
patients  were  all  women,  and  their  condition  varied  from 
simple  nervousness  to  hysteria  and  melancholia.  Some 
were  also  of  a  rheumatic  diathesis.  Dr.  Billod  inforn*d 
the  author  that  he  had  observed  spots  of  ecchymosis  on 
the  dead  bodies  of  persons  who  had  suffered  from  melan- 
cholia. This  phenomenon  of  the  spontaneous  occurrence 
of  ecchymosis  in  nervous  women  is  a  fact  possibly  of 
some  importance  in  a  medico-legal  point  of  view. 

Gummy  Tumor  of  the  Tongue  occurring  Forty- 
three  Years  after  Infection. — Dr.  Pellizzari  relates 
the  case  of  a  man,  sixty -five  years  of  age,  who  in  1840 
had  a  chancre,  followed  by  pains  in  the  head  and  bones, 
an  eruption  of  the  skin,  and  mucous  patches  in  the  mouth. 
He  was  treated  with  iodides  and  mercury,  and  was  appar- 
ently cured.  He  married  in  1855,  had  four  healthy  chil- 
dren,  and  enjoyed  excellent  health  up  to  November,  1883. 
At  that  time  a  hard  nodule  appeared  on  the  left  side  of  the 
tongue  anteriorly.  This  was  followed  by  others,  which 
soon  became  confluent  and  formed  an  elongated  tumor. 
These  neoplasms  were  at  first  hard,  then  became  softened 
and  finally  ulcerated.  When  the  patient  presented  him- 
self for  treatment,  the  tip  of  the  tongue  was  indurated  and 
showed  three  points  of  ulceration.  There  was  no  glan- 
dular engorgement.  Under  mercury  and  iodide  of  sodium 
the  ulcers  healed  and  the  induration  diminished  very 
markedly. — Journal  de  Mkdecine  de  Paris,  August  30, 
1884. 

The  Reduction  of  Paraphimosis. — The  following  is 
the  method  successfully  pursued  by  Dr.  Zakharevich  in 
the  reduction  of  a  number  of  cases  of  paraphimosis 
(LAbeille  Midicale^  No.  32,  1884).  After  carefully 
anointing  the  strangulated  parts  with  oil  or  vaseline,  he 
places  the  tips  of  the  thumb  and  fingers  on  the  glans  so 
as  to  completely  surround  it,  and  then  makes  firm  and 
gradual  pressure.  After  three  or  four  minutes  of  this 
steady  pressure,  as  a  rule,  the  glans  is  reduced  to  its  nor- 
mal size.  Then,  the  pressure  being  maintained  by  the 
thumb,  the  ring,  and  little  fingers,  the  constricting  ring  is 
grasped  by  the  index  and  middle  fingers  and  the  prepuce 
in  this  manner  drawn  down.  Reduction  is  thus  accom- 
plished easily  and  quickly,  the  most  difficult  case  having 
required  but  fifteen  minutes  for  its  cure.  In  the  cases 
treated  by  him  the  ages  of  the  patients  varied  from  three 
to  fifty-seven  years,  and  the  duration  of  the  condition 
from  twelve  hours  to  thirty  days. 

Naphthol  in  the  Treatment  of  Scabies. — Dr. 
Samuel  Rona  has  treated  a  number  of  cases  of  itch  by  a 
ten  to  twenty  per  cent,  solution  of  naphthol  in  oil.  If 
chronic  eczema  coexist  the  solution  should  not  be 
stronger  than  two  or  three  per  cent.  In  upward  of  a  hun- 
dred cases  in  which  the  remedy  was  tried  the  author 
never  saw  any  symptoms  of  poisoning,  the  only  eflfect 
of  using  too  concentrated  solutions  being  the  pro- 
duction of  eczema.  The  application  should  be  made 
in  the  evening,  all  the  parts  affected  with  scabies  being 
thoroughly  rubbed  with  the  preparation.  The  next  morn- 
ing the  patient  takes  a  bath,  and  all  the  surface  reddened 
by  irritation  of  the  naphthol  is  dusted  with  rice  powder. 
Usually  one  application  is  sufficient  for  a  cure.  Some- 
times an  intense  itching  persists  for  some  days,  but  this 
was  attributed  to  the  coexisting  eczema. — La  France 
Midicale,  September  2,  1884. 

The  Relation  between  the  Ankle  Clonus  and 
THE  Patellar  Reflex. — In  cases  i^^  which  the  ankle 
clonus  is  very  marked,  as  in  old  hemiplegia  or  in  tabes, 
it  coexists  ordinarily  with  an  exaggerated  patellar  tendon 
reflex.  Certain  authors,  struck  with  this  coincidence, 
have  referred  both  phenomena  to  the  same  cause  and 
look  upon  them  as  of  identical  semeiological  value.  This 
view  is  opposed  by  M.  de  Fleury  {Revue  de  Midecine^ 
August,   1884),  who  asserts  that  in  a  large  number  of 


404 


THE   MEDICAL  RECORD 


[October  ii,  1884. 


cases  the  foot  phenomenon  is  met  with  when  the  patellar 
reflex  is  normal  or  even  abolished.  He  relates  a  number 
of  instances  in  proof  of  this  assertion.  He  also  made 
some  experiments  showing  that,  in  cases  in  which  the 
ankle  clonus  and  exaggerated  patellar  reflex  coexisted, 
t^e  former  could  be  made  to  disappear  while  the  foot  and 
knee  tendon  reflexes  persisted.  This  was  done  by  making 
the  affected  member  anaemic  by  means  of  an  Esmarch's 
bandage.  He  concludes,  therefore,  that  those  who  main- 
tain an  identity  of  causation  of  these  two  phenomena  are 
in  error,  and  that  the  ankle  clonus  is  to  be  explained  in 
some  other  way. 

The  Treatment  of  Snake-Bites. — Mr.  J.  Mildred 
Creed,  in  a  paper  read  before  the  New  South  Wales 
Branch  of  the  British  Medical  Association  {Australasian 
Medical  Gazette^  No.  10,  1884),  states  as  his  belief  that 
many  of  the  alarming  symptoms  following  a  snake-bite 
are  due  rather  to  fright,  pure  and  simple,  than  to  the 
poison  received  from  the  fangs  of  the  snake.  He  relates 
a  number  of  cases  in  support  of  this  assertion.  The  bite 
had  been  promptly  excised  in  every  case,  and  only  two 
of  the  patients  presented  any  alarming  symptoms.  In 
one  of  these  cases  the  patient  recovered  speedily  on  be- 
ing assured  that  there  was  no  cause  for  fear,  although 
she  had  a  short  time  before  been  apparently  at  death's 
door.  The  other  case  was  simply  one  of  profound  intoxi- 
cation resulting  from  the  large  amount  of  brandy  which 
had  been  given  as  an  antidote.  The  author  also  relates 
several  other  cases  of  people  who  had  died  of  fright  after 
being  bitten  by  non-venomous  reptiles.  He  does  not 
believe  that  there  is  any  physiological  antidote  to  snake 
poison,  and  thinks  that  the  only  effectual  means  of 
averting  serious  consequences  is  by  the  prevention  of 
the  absorption  of  the  poison.  This  is  best  done  by  the 
early  stoppage  of  the  circulation  in  the  wounded  limb  by 
the  application  of  a  strong  ligature,  and  the  excision  of 
the  bite.  The  reckless  administration  of  alcohol  the 
author  condemns  as  not  only  useless  but  harmful.  He 
recommends  the  administration  of  ether  by  inhalation 
as  answering  a  double  indication,  that  of  slight  stimula- 
tion and  of  removing  the  feeling  of  dread  by  inducing 
unconsciousness.  The  ether  should  be  administered  for 
one  or  two  hours,  when  the  patient  may  be  allowed  to 
recover  sensibility  to  such  an  extent,  as  to  enable  the 
surgeon  to  judge  of  his  condition.  After  this,  should  it 
be  necessary,  he  might  be  again  brought  under  the  influ- 
ence of  the  anaesthetic  and  kept  there  as  long  as  desired. 
Any  other  symptoms  which  may  arise  are  to  be  treated 
according  to  general  principles. 

The  Micrococci  of  Dysentery. — At  a  recent  meet- 
ing of  the  Medical  Society  of  the  Caucasus,  Dr.  Gaudelin, 
of  Tiflis,  exhibited  micro-organisms  found  by  him  in  the 
intestine  and  liver  of  patients  dead  of  dysentery.  The 
micrococci  were  found  in  great  numbers  in  the  digestive 
tube,  covering  the  surface  and  penetrating  all  the  tunics 
of  the  intestine.  They  were  especially  numerous  within 
and  about  the  veins  of  the  sub-mucous  layer  and  in  the 
muscular  coat.  In  the  liver  they  filled  the  capillaries 
and  the  branches  of  the  portal  vein.  The  author  also 
found  bacilli  in  the  mucous  and  submucous  layers  of  the 
large  intestine,  but  not  elsewhere.— y^»r«tf/  de  Mhdecine 
de  FariSy  August  30,  1884. 

Mild  Forms  of  Typhoid  Fever. — Laflbni  thus  classi- 
fies the  milder  forms  of  typhoid  fever :  Forms  slight  by  their 
duration.,  forms  slight  by  their  intensity,  and  a  third  class 
slight  by  duration  and  intensity.  Of  forms  slight  as  to 
their  duration,  constant  symptoms  are  :  splenic  tumefac- 
tion, bronchial  cfttarrh,  and  fever.  The  course  of  this 
last  characterizes  the  different  varieties.  The  temperature 
either,  as  in  ordinary  attacks  of  typhoid  fever,  has  three 
well-marked  stages — period  of  ascending  oscillations,  sta- 
tionary period,  and  period  of  decline — or  is  limited  to 
one  or  two  of  these  stages  only.  In  some  rare  cases  the 
fever  assumes  the  course  of  a  quotidian  intermittent,  with- 
out repeated  rigors  or  sweats.     Of  the  forms  slight  by 


intensity,  the  duration  may  be  long.  These  either  ap- 
proach the  classical  type,  or  are  irregular  when  the  fever 
is  subcontinuous  or  intermittent,  or  is  partly  continued, 
partly  intermittent.  Splenic  tumor  is  a  constant  symp. 
tom.  These  slight  forms  must  be  considered  due  cither 
to  a  small  dose  of  the  poison  or  to  its  exhausted  activity, 
or  possibly  to  the  mode  by  which  it  gained  access  to  the 
organism,  as  well  as  to  the  conditions  of  receptivity  or 
organic  resistance  of  the  patient.  The  anatomical  altenu 
tions  are  identical  with  those  of  ordinary  typhoid  fever. 
There  is  no  constant  relation  between  their  extension 
and  the  intensity  or  gravity  of  the  clinical  form.  The 
diagnosis  is  very  important,  especially  as  regards  prophy- 
laxis. It  is  often  very  difficult.  The  splenic  tumor, 
rash,  pain  in  the  ileocaecal  fossa,  evening  headache, 
apathy  of  the  patient,  bronchial  catarrh,  often  good 
appetite,  notwithstanding  the  fever,  pulse  small,  and  very 
often  dicrotic,  are  the  chief  elements  of  a  sure  diagnosis. 
The  prognosis  in  children  is  good;  in  adults  it  is  sub- 
ordinated to  the  docility  of  the  patients  and  to  the  possibil- 
ity of  complication ;  in  old  people,  it  is  always  more  doubt- 
ful. As  to  treatment,  the  author  recommends  calomel  for 
the  first  three  or  four  days,  then  mineral  acids  or  benzoic 
acid.  Except  the  general  or  partial  cold  bath,  antipy- 
retics, especially  in  cases  of  long  duration,  are  harmful  or 
useless. 

Abscess  of  the  Cerebellum  Consbcutive  to  Otitis 
Media. — In  a  communication  addressed  to  the  Society 
of  Anatomy  and  Physiology  of  Bordeaux  (Journal  de 
Medicine  de  Bordeaux^  August  24,  1884),  Dr.  E.  Cap- 
deville  relates  the  case  of  a  woman,  twenty-tour  years  of 
age,  admitted  to  hospital  suffering  from  obscure  cerebral 
symptoms.  She  lay,  always  on  the  left  side,  in  a  state  of 
semi  stupor,  vomiting  occasionally,  and  complaining  of 
an  intense  general  cephalalgia.  She  had  a  discharge  from 
the  right  ear  dating  back  seven  months,  and  recently  an 
abscess  had  formed  and  opened  spontaneously  over  the 
tip  of  the  right  mastoid  process.  At  the  autopsy  the  le- 
sions of  otitis  media  with  condensing  osteitis  of  the  mas- 
toid process  were  found.  The  meninges,  cerebrum,  and 
sinuses  of  the  brain  were  all  normal,  but  in  the  right 
lobe  of  the  cerebellum  was  an  abscess  containing  over 
three  ounces  of  pus.  The  mode  of  propagation  of  the 
inflammation  from  the  ear  to  the  cerebellum  could  not 
be  discovered,  and  possibly  the  latter  may  have  been 
merely  coincidental  and  independent  of  the  otitis. 

Iodine  Injections  in  Hydrarthrosis  of  the  Knee- 
JoiNT. — Dr.  Douglas  Morton,  in  The  Americdn  Prac- 
titioner^ July,  1884,  speaks  very  highly  of  iodine  injec- 
tions into  the  knee-joint  for  the  cure  of  hydrarthrosis. 
He  bases  his  favorable  opinion  on  the  excellent  results 
obtained  in  four  recent  cases  of  this  kind.  The  views  of 
most  surgical  authorities  are  against  all  such  procedures, 
as  may  be  seen  from  the  following  extracts :  *'*  I  have 
not  been  so  bold  as  to  use  injections  for  the  permanent 
cure  of  this  affection,  convinced  that  the  practice  must 
be  fraught  with  danger  "  (Gross).  "  Tapping,  iodine 
injections,  etc.,  notwithstanding  considerable  testimony 
in  their  favor,  are  remedies  of  doubtful  propriety" 
(Hamilton).  "  This  mode  of  treatment  has  been  used 
with  great  success  by  several  European  surgeons;  as, 
however,  the  plan  is  necessarily  attended  by  some  risk, 
it  should  not  be  employed  except  in  very  chronic  cases 
which  have  resisted  other  modes  of  treatment  .  .  • 
Even  the  simple  use  of  the  aspirator  in  these  cases  is  at- 
tended with  some  danger,  as  shown  by  fatal  results 
which  have  occurred  in  the  hands  of  Dubreuil,  and  of 
McDonnell,  of  Dublin"  (Ashhurst).  '*  In  very  chronic 
and  obstinate  cases  paracentesis  of  the  joint  by  means  of 
the  aspirator  has  been  employed  with  marvellous  success. 
Sir  J.  Fayrer  was  one  of  the  strongest  advocates  "  (Bry- 
ant). "  But  when  these  (the  usual  remedies)  have  failed 
.  .  .  the  joint  must  be  injected  with  iodine.  Care 
must  be  taken  to  exclude  air.  .  .  .  The  case  may 
be  converted  into  one  of  acute  abscess.     But  generally 


October  1 1,  1884.] 


THE  MEDICAL  RECORD. 


405 


it  does  well,  and  the  patient  recovers  with  more  or  less 
rtiffening"  (Holmes),  "The  results  of  this  operation 
Hnjecting  iodine)  may  be  divided  into  four  classes  :  (i) 
Complete  cure  with  preservation  of  mobility;  (2)  cure 
with  certain  amount  of  stiffness  ;  (3)  complete  failure ; 
(4)  suppuration  and  injury  to  joint.  The  first  and  fourth 
classes  are  uncommon,  l^e  operation  should  not  be 
done  except  after  trial  and  failure  of  other  remedies'* 
(Panas,  quoted  in  Holmes*  "  Surgery  **).  "  Dangerous 
both  to  life  and  limb,  and  can  very  rarely  be  justifiable  ** 
(Keedey).  "  If  these  means  fail,  and  the  absence  of  false 
bodies  and  osteophytes  has  been  verified,  the  joint  may 
be  mjected  with  iodine  "  (Barwell).  "  If  these  means 
fail,  we  have  a  very  powerful  method  of  cure  at  our  com- 
mand in  the  injection  of  the  joint  with  tincture  of  iodine. 
This  plan,  a  sufficiently  bold  one,  has  been  much  em- 
ployed by  Jobert,  Velpeau,  and  Bonnet.  .  .  .  Ac- 
cording to  the  statement  of  the  French  surgeons,  it  has 
in  no  case  been  followed  by  any  serious  consequences, 
but  in  several  instances  by  a  complete  cure  without  an- 
kylosis. ...  In  one  case  of  hydrarthrosis  of  the 
knee  in  an  old  man,  in  which  I  employed  it,  about  six 
ounces  of  thin  synovia  were  drawn  off  and  a  drachm  of 
strong  tincture  of  iodine  was  injected.  Slight  inflamma- 
tion ensued,  and  the  disease,  which  was  of  two  years' 
standing,  was  completely  cured.  The  chief  points  that 
appear  to  require  attention  are  that  no  inflammation  be 
going  on  at  the  time,  there  being  no  tenderness  or  pain 
in  moving  the  joint,  the  effusion  being  quite  passive  and 
of  a  very  chronic  character,  and  above  all  that  no  air  be 
allowed  to  enter  with  the  injected  fluid"  (Erichsen). 
"  Iodine  injections  in  hydrarthrus  are  made  by  few  sur- 
geons. I  have  seen  them  made  three  times  and  have 
made  two,  always  with  good  results.  .  .  .  Cases 
have  also  occurred  where  severe  inflammations  of  the 
joint  have  resulted  after  these  iodine  injections,  which 
have  been  inost  used  in  France  because  they  are  a 
French  invention  (of  Bonnet  and  Velpeau)  ;  as  so  often 
happens  in  traumatic  articular  inflammations,  the  acute 
serous  s3movitis  often  becomes  purulent.  .  .  .  It  is 
always  dangerous  to  joint  and  to  life,  and  hence  should 
be  done  as  rarely  as  possible  *'  (Billroth). 

Dr.  Morton  believes  that  the  prejudice  against  the 
operation  prevailing  in  the  minds  of  most  surgeons  con- 
sists of  the  too  lingering  remains  of  a  belief  long  domi- 
nant in  the  professional  mind,  that  the  joints,  and  particu- 
larly the  knee-joint,  could  not  be  surgically  interfered 
with  except  at  great  risk.  Now  that  we  have  learned, 
especially  from  McEwen  and  Ogston,  how  very  tolerant 
are  the  joints  of  the  knife  and  the  saw ;  and  since  we 
hold  it  to  be  so  light  a  matter  to  throw  iodine  into  the 
tunica  vaginalis,  it  does  appear  anomalous  that  any  one, 
on  any  supposed  general  principles,  should  consider  it 
highly  dangerous  to  inject  iodine  into  the  synovial  sac 
of  the  knee-joint. 

Stress  has  been  put  upon  the  danger  of  admitting  air. 
The  author  can  understand  how  importance  should  have 
been  attached  to  such  an  accident  before  the  days  of 
antiseptic  surgery.  But  now  he  cannot,  and  in  his  own 
operations  air  was  admitted  freely — so  much  so,  that 
when  the  injected  iodine  was  forced  out  by  pressure  a 
multitude  of  air-bubbles  would  come  with  it.  He  took 
pains  to  bring  the  iodine  in  contact  with  as  much  of  the 
membrane  as  had  been  touched  by  air,  and  by  this,  he 
believes  its  admission  was  rendered  perfectly  harmless, 
and  therefore  made  no  special  effort  to  prevent  it.  With- 
out the  use  of  iodine  or  some  other  powerful  disinfect- 
ant, he  should  regard  admission  of  air  into  the  joint 
dangerous,  and  believe  it  very  probable  that  the  fatality 
occurring  in  the  practice  of  McDonnell  and  Dubreuil, 
mentioned  by  Ashhurst,  was  due  to  this  cause.  It  was 
sjud  by  Volkmann,  in  his  address  on  antiseptic  surgery 
before  the  International  Congress  in  London,  that  results 
m  sargei^  were  no  longer  involved  in  the  uncertainty  of 
former  times.  Then  the  work  of  the  surgeon  was  like 
that  of  the  agriculturist,  dependent  in  its  issue  upon  con- 


ditions which  he  could  neither  anticipate  nor  control ; 
bnt  now,  it  is  rather  like  that  of  the  skilled  mechanic, 
the  conditions  of  whose  work  are  largely  subject  to  his 
control  and  from  whom  we  may  confidently  expect  re- 
sults. Dr.  Morton  does  not  know  that  this  is  true  to 
the  full  extent  of  the  analogy,  but  this  is  certain, 
that  the  striking  statement  places  surgery  downrightly 
upon  the  basis  of  the  inductive  method,  upon  which 
alone  substantial  progress  is  possible.  In  making  a 
practical  application  of  this  method  of  reasoning  to  the 
question  before  us,  he  thinks  we  may  safely  conclude 
that  two  points  are  definitely  and  finally  settled :  first, 
air  may  be  freely  admitted  into  a  synovial  sac  and  no 
harm  result ;  and,  second,  undiluted  officinal  compoimd 
tincture  of  iodine  may  be  safely  injected.  Any  doubt  as 
to  these  particular  points  may  be  regarded  as  forever 
eliminated  from  the  question,  which  is  now  narrowed 
down  to  conditions  belonging  to  the  patient's  state  of 
health  and  to  his  surroundings.  Diseased  kidneys  or 
bad  hygienic  conditions  rendering  the  result  of  any  sur- 
gical operation  doubtful  may  lead  to  disaster  here.  But 
these  conditions  may  be  ascertained  by  reasonably  care- 
ful investigation  ;  and,  after  failing  to  find  any  unfavor- 
able condition,  we  may  operate  with  the  expectation  of 
a  good  result. 

The  Detection  of  Mercury  in  the  Urine. — Ac- 
cording to  Dr.  Schuster  the  ordinary  tests  are  of  no  value 
in  the  detection  of  very  minute  quantities  of  mercury  in 
the  urine.  He  recommends  the  treatment  of  the  fluid  to 
be  examined  according  to  the  plan  proposed^by  the 
chemist  Herr  Schridde.  The  urine  is  acidulated  by  mu- 
riatic acid  and  submitted  to  a  current  of  sulphuretted 
hydrogen  and  then  set  aside  to  stand  for  twenty-four 
hours.  The  sediment  which  forms  contains  sulphide  of 
mercury,  uric  acid,  mucus,  etc  This  is  separated  by 
filtration,  and  both  the  filter  and  the  sediment  which  it 
retains  are  treated  by  nitro-muriatic  acid,  and  then  dried 
until  no  more  nitric  vapors  arc  given  off.  The  residue 
is  then  dissolved  in  a  small  amount  of  water  and  the 
solution,  slightly  acidulated,  is  treated  by  the  ordinary 
method  of  Furbringer.  By  this  procedure  it  is  possible, 
Dr.  Schuster  says,  to  detect  ^  ^]f^  ^  grain  of  mercury. 
Archives  M^dicales  Beiges ^  July,  1884. 

Typhoid  Ulcerations  of  the  Throat. — ^The  follow- 
ing are  the  conclusions  of  a  memoir  read  by  Dr.  £.  Rapin 
before  the  Medical  Society  of  Geneva:  i,  the  frequency 
of  the  occurrence  of  typhoid  lesions  in  the  fauces  is  greater 
than  most  authors  admit ;  2,  typhoid  fever  may  begin  with 
a  sore  throat  accompanied  by  indolent  ulcerations ;  3,  the 
ulcers  are  superficial,  rounded  or  oval,  with  slightly  ele- 
vated borders,  and  indolent,  their  seat  of  predilection  is 
on  the  anterior  surface  of  the  uvula  and  the  anterior 
pillars  of  the  fauces ;  4,  the  diagnosis  is  usually  difficult, 
and  can  only  be  determined  with  certainty  by  observing 
the  general  symptoms  and  the  course  of  the  disease ;  5, 
the  lesions  which  characterize  them  are  referable  to  the 
lymphatic  system  ;  6,  these  lesions  are  identical  with  those 
observed  in  other  organs  in  this  disease,  and  they  indicate 
an  identical  pathogenesis ;  7,  they  are  due  to  the  direct 
penetration  of  the  micro-organisms  of  typhoid  fever  into 
the  follicles  of  this  region. — Rei/isia  de  Medicina  y  Ci- 
rurgia  Prdticas^  August  7,  1884. 

Fracture  of  Inferior  Maxilla  Treated  with  Sil- 
ver-wire Suture. — Dr.  J.  Craig  Miller,  of  Lake  City, 

writes :  "  John  R ,  a  miner  at  the  U16  mine,  was 

thrown  from  the  bucket  and  fell  about  fifteen  feet.  His 
inferior  maxillary  bone  was  fractured  at  the  symphysis. 
I  was  sent  for  (four  miles)  and  arrived  about  two  hours 
after  the  accident ;  found  the  left  half  displaced  down- 
ward about  half  an  inch.  It  was  replaced  without  diffi- 
culty and  the  teeth  firmly  fastened  together  with  silver 
wire,  and  lead-water  and  laudanum  applied.  No  other 
treatment.  I  thought  the  wire  would  be  sufficient,  as  the 
seat  of  the  fracture  was  directly  in  the  centre,  and  it 
has  proved  so.     The  man  is  over  forty  years  of  age." 


4o6 


THE   MEDICAL  RECORD. 


[October  ii,  1884. 


The  Medical  Record: 


A  Weekly  journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 

Published  by 
WM.  WOOD  &  Co..   Nos.  56  and  58  Ufayette  Place. 

New  York,  October  ii,  1884. 

THE  AMERICAN  PUBLIC  HEALTH  ASSOCIA- 
TION. 
This  body  is  to  meet  in  its  twelfth  Annual  Session  at  St. 
LouiSy  Mo.,  on  October  14th  inst.  The  session  promises  to 
be  one  of  unusual  interest,  both  on  account  of  the  locality 
where  the  meeting  is  held,  and  the  importance  of  the  sub- 
jects which  will  be  discussed.  It  is  the  first  time  that  the 
Association  has  held  a  meeting  in  what  may  properly  be 
called  '*  the  West,"  If  we  may  judge  by  the  busy  note  of 
preparation  for  the  meeting  which  reaches  us,  and  the 
past  reputation  of  the  great  metropolis  of  the  West  for 
munificent  hospitality,  the  forthcoming  session  of  the 
Association,  at  St.  Louis,  will  be  on  a  scale  of  grandeur 
hitherto  quite  unknown  to  that  hard-working  body. 

All  experience  proves  that  however  royally  any  city 
entertains  this  Association,  it  reaps  one  hundred-fold 
benefit  from  the  influence  which  the  latter  exerts  upon 
the  State  and  the  municipal  governments.  Public 
opinion  is  also  enlightened,  and  rendered  more  favorable 
to  the  establishment  of  a  well-organized  sanitary  adminis- 
tration, and  the  enforcement  of  health  laws  and  ordi- 
nances. 

'  The  Association  meets  this  year  at  a  very  important 
juncture  of  sanitary  affairs,  and  standing  as  our  great 
National  Congress  of  Public  Hygiene,  the  results  of  its 
deliberations  will  be  of  wide  import.  It  is  the  only  or- 
ganization which,  by  its  national  character,  its  age,  its 
reputation  for  honest  and  useful  work,  and  the  high 
official  and  scientific  positions  of  its  members,  can  at  once 
grasp  the  great  municipal  State,  national,  and  inter- 
national sanitary  questions  of  the  day,  and  formulate 
principles  which  must  guide  the  action  of  legislatures. 
We  look  forward,  therefore,  to  this  meeting  of  the  Asso- 
ciation, with  the  expectation  that,  in  addition  to  its  in- 
teresting daily  work,  some  questions  of  pressing  im- 
portance which  must  occupy  public  attention  during  the 
coming  year  will  be  duly  considered  and  suitable  action 
taken  thereon. 

Perhaps  the  most  important  subject  which  can  engage 
the  attention  of  the  Association  will  be  our  protection 
against  an  invasion  of  cholera  during  the  next  year.  It 
is  a  fortunate  circumstance  for  us  that  this  Oriental 
plague,  in  its  progress  westward,  has  dallied  so  long 
beneath  the  sunny  skies  of  Italy.  It  has  thereby  given 
us  ample  warning  of  its  intended  invasion,  and  enabled 
the  Association  to  consider,  in  the  most  deliberate  man- 
ner, the  defensive  measures  which  should  be  adopted. 


This  is  the  first  time  in  the  history  of  cholera  epidemic 
in  this  country,  that  there  has  been  an  organized  body  of 
sanitarians  and  health  authorities  prepared,  not  only  to 
bring  to  the  discussions  of  the  questions  of  prevention 
the  latest  investigations  of  science  and  the  experiences 
of  sanitarians,  but  the  large  majority  of  them  are  them- 
selves  the  official  guardians  of  the  public  health  of  their 
respective  communities,  and  the  appointed  agents  to 
enforce  preventive  measures.  The  country  may  there- 
fore reasonably  expect  that,  before  the  Association  closes 
its  session,  cholera-prevention  in  all  its  phases  will  be 
discussed  by  experts,  definite  lines  of  action  will  be  de- 
termined upon,  and  such  combinations  of  authorities  be 
organized  as  will  give  concert  of  action  in  the  enforce- 
ment of  defensive  measures  throughout  the  length  and 
breadth  of  the  land. 

A  second  subject  demanding  the  attention  of  the  Asso- 
ciation is  the  condition  of  our  system  of  quarantine.  The 
simple  truth  is  that  our  so-called  quarantines  are  a  dis- 
grace to  the  country.  They  are  little  else  than  gigantic 
political  schemes  of  plundering  commerce  and  travel  under 
the  sanction  of  law.  At  home  and  abroad  they  are  the 
laughing-stock  of  all  advanced  students  of  preventive 
medicine.  Thus  far  in  the  history  of  the  Association 
this  great  defect  in  our  system  of  health  organization  has 
been  allowed  to  exist  without  even  a  protest.  Numerous 
papers  have  been  presented  to  that  body,  discussing  the 
general  subject  of  quarantines,  but  they  have  led  to  no 
practical  results.  We  believe  the  time  is  now  opportune 
for  the  Association  to  take  decisive  measures  toward  re- 
forming our  system  of  coast  defences  against  foreign 
pestilences,  and  the  country  will  be  disappointed  if,  in 
this  emergency,  the  subject  is  again  passed  over  in  si 
lence. 

Again,  the  relations  of  the  general  Government  to  the 
measures  of  preventing  the  introduction  of  foreign  epi- 
demics into  this  country,  and  their  spread  from  one  Slate 
to  another,  demands  the  most  serious  consideration  of 
the  Association. 

Through  the  efforts  of  the  Association  a  plan  was 
perfected  in  1879  of  associating  the  general  Govern- 
ment with  State  and  local  health  authorities  in  well- 
devised  and  concerted  methods  of  action  to  prevent  the 
invasion  and  spread  of  epidemics.  For  three  years  that 
plan  worked  admirably  and  effectually,  and  the  country 
was  protected,  as  never  before,  from  the  most  dreaded 
of  exotic  plagues.  The  system  of  co-operation  then 
established,  with  so  much  prudence  and  wisdom,  has 
finally  been  destroyed  by  the  reckless  ambition  of  men 
intent  only  on  wielding  that  power  which  comes  of  ex- 
pending the  public  funds.  The  National  Board  of 
Health,  selected  with  so  much  care  by  the  President  and 
Senate,  as  the  agent  of  the  Government  in  its  fiiture  san* 
itary  work,  has  been  superseded  by  an  officer  of  the 
Treasury  Department  without  law  or  appointment  The 
laws,  so  carefully  drawn  to  guard  against  the  encroach* 
ment  of  National  upon  State  and  Municipal  authority, 
and  secure  the  judicious  and  economical  use  of  the  pub- 
lic money,  have  been  purposely  allowed  to  lapse,  that 
there  might  be  no  restrictions  upon  the  self-constituted 
agent  who  usurped  the  office  and  functions  of  the  Board 
of  Health.  To-day,  therefore,  the  field  of  National  san- 
itary legislation  is  a  blank,  and  it  is  for  the  Association 


October  ii,  1884*] 


THE  MEDICAL  RECORD. 


407 


to  detcnninc  whether  the  interests  of  the  public  health 
will  be  best  subserved  by  a  well-organized  Health  De- 
partment at  the  capital,  acting  under  the  restrictions  of 
suitable  laws,  or  by  an  irresponsible  bureau  oflScer  with- 
out sanitary  knowledge  or  experience,  and  governed  by 
DO  other  law  than  his  own. 

Bearing  upon  the  same  subject  is  a  question  of  far 
wider  application,  which  the  Association  ought  to  con- 
sider. We  refer  to  international  co-operation  in  the  fre-^ 
veniion  of  contagious  and  infectious  diseases.  There  can 
never  be  any  radical  measures  adopted  and  enforced 
which  will  strike  at  the  very  source  of  the  propagation 
and  spread  of  epidemic  diseases  until  the  great  commer- 
cial nations  of  the  world  combine  in  good  faith,  and  each 
in  its  respective  sphere  of  operations  fulfil  its  whole  duty, 
whatever  that  may  be.  And  this  co-operation  can  never 
be  established  without  an  International  Conference  to 
which  these  commercial  powers  shall  send  delegates. 
The  National  Board  of  Health  succeeded  in  securing  one 
International  Conference,  by  act  of  Congress,  and  so 
popular  was  the  project  that  twenty-eight  nationalities 
I  sent  delegates.  The  informal  discussions  in  this  body  of 
the  measures  of  international  co-operation  proved  that 
another  conference,  the  delegates  to  which  were  em- 
powered to  agree  definitely  upon  propositions  to  be  sub- 
mitted to  their  respective  Governments,  could  effect  an 
international  sanitary  league,  offensive  and  defensive, 
which  would  eventually  suppress  such  pestilences  as 
I       cholera. 

The  Public  Health  Association  is  capable  of  influen- 
1  dng  Congress  to  take  the  initial  step  in  calling  another 
I  conference  of  commercial  nations,  and  the  result  could 
i  scarcely  fail  to  be  an  agreement  upon  the  terms  of  a 
treaty  which  would  bind  these  nations  to  the  rigid  en- 
;  forcement  of  adequate  regulations  to  prevent  the  trans- 
[  portation  of  infectious  and  contagious  matters  or  dis- 
I       eases. 

During  the  present  session  of  the  Association  the  State 
Boards  of  Health  are  to  meet  in  conference.  The 
tendency  of  this  meeting  will  be  to  review  the  project  of 
a  separate  Association  of  State  Boards  of  Health.  The 
result  of  such  a  step  would  prove  eminently  disastrous  to 
public  health  reform  in  this  country.  The  Public  Health 
•  Association  stands  to-day  the  foremost  of  our  great  na- 
tional bodies,  and  is  the  recognized  embodiment  of  scien- 
tific and  practical  sanitary  knowledge  and  experience  in 
this  country.  During  the  twelve  years  of  its  existence  it 
has  published  a  series  of  annual  volumes  Which  are  un- 
surpassed by  any  other  Association  for  real  merit.  Its 
influence  on  public  thought  and  opinion,  and  on  legisla- 
tion, both  State  and  national,  is  powerfiil,  and  when  con- 
centrated on  practical  reforms,  is  decisive.  Any  such 
dismemberment  of  the  Association  as  this  movement 
of  the  State  Boards  of  Health  seems  to  contemplate 
would  be  a  most  inglorious  suicide.  Far  better  will  it 
be  for  the  future  of  sanitary  reform  and  administration 
in  the  United  States  to  enlarge  the  scope  and  plan  of 
the  original  organization,  so  that,  while  there  may  be  the 
greatest  diversity  of  discussion,  there  shall  be  unity  of 
action,  and  the  voice  that  shall  pronounce  the  judgment 
and  conclusions  of  the  assembled  congress  of  health 
authorities  shall  continue  to  be  that  of  the  American 
Public  Health  Association. 


THE  FIFTH  VOLUME  OF  THE  INDEX  CATALOGUE.* 
Th£  appearance  of  the  fifth  volume  of  the  Index  Cata- 
logue of  the  Library  of  the  Surgeon- General's  office  will  be 
hailed  with  the  greatest  satisfaction  by  the  writers  and 
workers  of  the  profession,  as  adding  another  volume  to  the 
admirably  exhaustive  series  which  have  opened  such  won- 
derful treasures  of  information  and  reference.  Under  no 
other  auspices  and  under  no  other  management  could  such 
work  be  accomplished,  than  those  which  centre  in  the  Sur- 
geon-General's office  under  the  direction  of  the  talented 
librarian,  Dr.  John  S.  Billings.  In  fact  in  no  other 
country  has  such  a  thing  been  attempted,  and  it  is  safe  to 
say,  backed  by  the  testimony  of  those  who  ought  to  know, 
that  in  no  other  place  has  the  foundation  for  such  work 
been  laid.  The  present  volume  embraces  an  equal  scope 
with  the  others,  is  of  equal  size,  and  comprises,  as  might 
be  anticipated,  an  almost  fabulous  amount  of  references 
within  its  limits,  viz.,  from  Flaccus  to  Hearth.  In  brief 
it  includes  15,555  author-titles,  5,755  volumes,  and 
13,596  pamphlets,  also  8^069  subject-titles  of  separate 
books  and  pamphlets,  and  341 127  titles  of  articles  in 
periodicals. 

The  utility  of  the  series  proves  itself  more  and  more 
with  each  volume,  and  correspondingly  indicates  the 
hearty  professional  endorsement  of  governmental  patron- 
age. The  best  that  can  be  said  is  that  the  good  work  is 
likely  to  go  on,  and  every  scholar  in  the  profession  will 
wish  it  Godspeed 

THE   NEW   CIVIL   SERVICE    REGULATIONS    AND    THE 
MEDICAL  PROFESSION. 

An  advertisement  appears  in  the  daily  papers  to  the 
effect  that  "an  open  competitive  examination,  under 
the  New  York  State  Civil  Service  rules,  will  be  held  Oc- 
tober 2 2d,  at  the  New  York  Academy  of  Medicine,  to 
fill  vacancies  in  the  regular  medical  staff  of  the  Hudson 
River  State  Hospital  for  the  Insane,  at  Poughkeepsie, 
N.  Y."  It  is  further  stated,  that  the  examination  is  open 
to  all  graduates  of  reputable  medical  colleges. 

This  announcement,  already  indicated  in  a  previous 
issue  of  The  Medical  Record,  is,  we  believe,  the 
first  application  to  medical,  positions  of  the  New  York 
Civil  Service  regulations,  which  went  into  effect  last 
August. 

The  regulations  that  have  been  adopted  by  this  city 
show  the  general  scope  of  those  for  the  whole  State,  and 
as  a  knowledge  of  them  may  prove  of  some  value  to 
physicians  who  intend  to  become  connected  with  the 
public  service  we  venture  to  give  some  of  the  details 
here. 

The  positions  which  are  obtainable  now  only  after 
competitive  examination  are  those  of  physician,  surgeon, 
chief  of  staff  of  hospital,  medical  ofiicer,  medical  super- 
intendent and  assistant  medical  superintendent,  inspector 
of  vaccination,  or  sanitary  inspector,  and  those  posi- 
tions in  the  Health  Department  requiring  a  medical  edu- 
cation and  experience. 

The  rules  also  require  an  examination  of  all  applicants 
for  the  positions  of  principal  matron,  head  of  training- 
school  for  nurses,  orderly,  nurse,  and  hospital  attendant 

These  positions  are  included  mainly  under  "  Schedule 

>  Index  Catalogue  of  the  Library  of  tlie  Suiyeon-General's  Office,  U.  S.  Anny. 
Attthon  and  Subjects.    Vol.  t.,  Flaocu»-Hearth.    Washington,  1884. 


4o8 


THE  MEDICAL  RECORD. 


[October  ii,  i 


D,"  which  includes  all  persons  for  whose  duty  special 
expert  knowledge  is  required ;  and  "  Schedule  E,"  which 
includes  physicians,  chemists,  nurses,  orderlies,  and 
other  hospital  and  asylum  attendants. 

Applicants  for  medical  positions  must  address  a  letter 
to  the  Secretary  of  the  Municipal  Service  Boards,  New 
York  city,  stating  their  age,  residence,  nativity,  etc  ; 
they  must  furnish  a  certificate  of  good  character,  and 
must  give  evidence  that  they  have  been  duly  authorized 
to  practise  njedicine  and  surgery.  The  examination 
takes  place  before  one  of  the  three  Examining  Boards 
appointed  by  the  mayor,  and  composed  of  three  citizens. 
The  examination,  besides  requiring  evidence  of  physical 
and  moral  qualifications,  includes  the  following,  with  the 
relative  weight  given  to  each :  medical  knowledge,  50 ; 
experience,  20;  efficiency  and  accuracy  in  work,  15; 
character  for  maintaining  discipline,  15.  Naturally,  cer- 
tain variations  from  this  are  made  in  accordance  with 
the  character  of  the  position. 

It  is  in  the  power  of  the  Advisory  Board  to  institute 
non-competitive  examinations  for  positions  in  the  De- 
partment of  Charities  and  Correction. 

In  regulation  30  it  is  stated  that  competitors  for  **  the 
superior  positions  in  Schedule  D  "  are  not  obliged  to 
produce  a  diploma,  but  a  certificate  from  some  reputable 
institution  of  having  studied  two  years,  or  a  certificate 
from  a  professional  man  of  having  studied  for  three  years 
will  suffice. 

This  provision,  as  will  be  seen,  furnishes  a  possible 
opening  for  politicians  to  get  in  their  friends  who  have 
not  been  regularly  qualified  as  physicians. ' 

The  Civil  Service  regulations,  if  carried  out  thoroughly, 
will  no  doubt  assist  to  raise  the  character  of  the  medical 
service.  Yet  it  must  be  admitted  that  the  character  of 
this  service  was  on  the  whole  very  good  under  the  old 
system.  Rumors  of  late,  however,  that  politics  has  too 
much  influence  in  the  Health  and  Police  Departments, 
lead  us  to  look  forward  with  pleasure  to  anything  that 
promises  to  remedy  these  existing  or  impending  evils. 


RECOGNITION   OF  HARD  PREPARATORY  WORK. 

One  of  the  earliest  observations  which  a  young  physician 
learns  to  make  is  that  of  the  enormous  disparity  which 
exists  in  the  education,  skill,  manners,  and  general  char- 
acter  of  physicians.  A  young  man  has  graduated  from  a 
classical  or  scientific  college,  has  spent  three  or  four 
years  at  a  leading  medical  school,  has  walked  the  hospitals, 
has  perhaps  subsequently  taken  special  courses  or  stud- 
ied in  £urope.  He  then  settles  in  practice  and  finds  that 
he  must  meet  as  a  brother,  and  must  be  estimated  by  the 
public  in  the  same  rank  with  a  person  who,  without  pre- 
liminary training,  graduated  at  some  provincial  institu- 
tion, after  a  course  of  study  lasting  practically  about  two 
years.  He  hears  derisive  comments  on  this  brother's  ig- 
norance or  on  that  colleague's  offensive  ways,  he  hears 
the  profession  ridiculed  for  its  incapacity  and  various 
standard  weaknesses,  and  has  to  take  his  share  of  the 
obloquy,  although  he  can  feel  without  vanity  that  he  is 
working  intelligently  and  with  some  success  in  his  chosen 
art.     There  seems  to  him  to  be  something  wrong. 

There  are  some  evidences  that  the  profession  every- 
where feels  that  these  differences  between  doctors  and 


doctors  are  very  great,  and  diat  the  ill*repute  which 
should  fall  on  the  careless  and  half-educated,  should  not 
have  to  be  shared  so  completely  by  those  who  have 
trained  themselves  thoroughly,  and  who  are  working  with 
an  honest  ambition. 

Some  time  ago  it  was  proposed  in  France  that  a  spe- 
cial class  of  physicians  should  be  established,  composed 
only  of  those  who  had  shown  some  evidence  of  unasaal 
capacity. 

In  England  and  this  country  there  is  a  tendency  to 
indicate,  in  giving  the  medical  title,  the  college  which 
bestowed  it,  provided  that  institution  was  one  whose 
character  deserved  such  special  designation.  Certainly 
the  degree  of  M.D.,  in  this  country,  has  a  very  unequal 
signification,  perhaps  to  a  greater  extent  even  than  that 
of  A.M. 

The  establishment  and  success  of  the  American  Acad- 
emy of  Medicine  helps'also,  in  a  measure,  to  give  credit 
to  those  who  have  taken  more  than  the  usual  pains  to 
prepare  themselves  for  a  learned  calling. 

We  are  inclined  to  favor  these  plans  which  aim  to  give 
recognition  to  hard  preparatory  work.  It  may  be  said 
that  such  ideas  are  not  *'  democratic,''  and  that  the  hum- 
ble graduate  of  an  obscure  school  may  become  a  better 
physician  than  he  who  is  trained  by  the  most  elaborate 
methods.  While  this  may  be  true  in  some  cases,  certain 
exceptions  do  not  invalidate  the  general  principle  laid 
down.  Hard  preliminary  work  deserves  a  little  recognir 
tion  other  than  the  slow  and  uncertain  recompense  fiir- 
nished  by  the  public. 


THE  PATHOLOGY  OF  SERPENT-POISONING. 

A  TRULY  scientific  account  of  the  lesions  produced  bj 
snake-poison  is  so  rarely  met  with  that  the  contribution  to 
this  subject  by  Dr.  Romiti,  of  Sienne,  in  the  Archives 
lialiennes  de  Biologic  (tom.  v.,  fasc.  i.),  is  of  great  interest. 

The  victim  was  a  man  forty  years  of  age.  Within  a  few 
moment  after  receiving  the  bite,  from  the  viper  cupis^  he 
fell  into  a  syncopal  condition,  the  heart  became  ex- 
tremely slow,  and  death  took  place  by  asphyxia  in  four 
hours  after  the  injury.  'At  the  autopsy,  twenty-three 
hours  post  mortem,  the  body  was  still  in  a  state  of  cada- 
veric rigidity  ;  but  it  was  noticeable  that  the  injured  arm 
was  less  rigid  than  the  other.  The  abdomen  was  enor- 
mously distended;  and  the  pupils  dilated.  The  cellu- 
lar tissue  around  the  wounded  surface  was  infiltrated 
with  a  sanguinolent  serous  fluid,  which  also  invaded  the 
muscular  tissue.  The  neighboring  veins  were  filled  widi 
black  fluid  blood,  though  the  wounds  had  not  entered 
any  vein.  The  superficial  cerebral  veins  were  filled  with 
blood  of  the  same  nature,  and  the  pons,  cerebellum,  and 
medulla  were  very  much  congested.  The  puknonarj 
vessels  were  full  of  blackish  blood,  as  were  those  of  the 
abdominal  organs ;  and  the  intestines  were  enormously 
distended  with  gas.  The  spinal  meninges  were  con- 
gested, and  the  vessels  of  the  cord  engorged. 

The  most  interesting  phenomena,  however,  were  those 
found  on  histological  examination  of  the  blood.  Two 
series  of  preparations  were  made  of  venous  blood  taken 
from  the  vessels  of  the  injured  arm.  The  first,  of  a  single 
drop  of  the  blood,  without  any  reagent ;  the  second,  of 
blood  treated  by  Bizzozero's  method,  that  of  mixing  the 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


409 


blood  with  a  seventy-five  per  cent,  solution  of  common 
salt,  slightly  coloring  with  methylene  violet,  and  pro- 
tecting with  paraffine.  Preparations  were  also  made  of 
blood  taken  from  other  parts  of  the  body.  The  best  re- 
sults were  obtained  from  the  examination  of  unmixed 
blood,  and  simply  colored  with  methylene  violet.  The 
red  blood-globules  were  normal  as  to  form,  but  were 
pale,  and  the  coloring-matter  was  diffused  in  the  plasma ; 
they  had,  moreover,  no  tendency  to  form  rolls,  as  in  the 
normal  condition.  Here  and  there  were  groups  of  leu- 
cocytes, and  in  their  midst  a  granular  substance.  Under 
a  1,500-power,  it  was  seen  that  the  granular  masses  were 
formed  of  piastrine  (Bizzozero),  or  haematoblasts(Hayem). 
The  red  disks  were  rapidly  dissociated  on  the  addition  of 
dfstilled  water. 

In  examining  blood  which  had  been  preserved  the 
same  results  were  obtained  as  with  fresh  blood.  The 
blood  which  had  been  kept  in  vessels  remained  fluid,  of  a 
syrupy  aspect,  dense,  and  wine-colored.  Three  months 
afler  death  it  had  the  same  characteristics,  never  emitting 
the  peculiar  odor  of  putrefaction,  but  only  a  strong  em- 
pyreumatic  odor,  very  like  Liebig's  meat  extract. 

The  liver,  spleen,  and  pancreas  were  examined  histo- 
logically. The  kidneys  were  in  a  state  of  commencing 
interstitial  nephritis.  In  the  liver,  the  capillaries  near 
the  interlobular  vein  were  markedly  engorged.  The 
pancreas  was  extremely  soft,  and  of  a  pale  yellow  color  ; 
there  was  complete  fatty  infiltration  of  the  granular 
cells,  which  accounted  for  the  macroscopic  appearance 
of  the  organ,  but  this  condition  may  have  existed  before 
the  injury  which  caused  death. 

It  is  interesting  to  note  here  the  experiments  of  Bufa- 
lini,  in  which  he  injected  30  c.c.  of  blood  from  the  inferior 
vena  cava  of  this  man  into  the  peritoneal  cavity  of  a 
guinea-pig ;  it  had  no  noxious  effect  whatever.  This  con- 
firais  the  results  obtained  by  Albertoni,  from  which  he 
concluded  that  the  active  and  poisonous  substance  of  a 
serpent  may  be  considered  as  a  true  poison,  and  its  ac^ 
tion  may  be  compared  to  that  of  an  alkaloid. 


BATHS  FOR  THE  POOR  IN  WINTER. 
Th«  communication  by  Dr.  Tauszky  in  the  present  issue 
is  one  of  much  interest  to  all  who  may  have  at  heart  the 
improvement  of  the  sanitary  condition  of  the  poorer 
classes.  The  proposition  to  provide  bathing  facilities 
at  all  times,  for  the  great  unwashed,  is  one  which  needs 
only  to  be  mentioned  to  be  commended.  It  is  impos- 
-sible  to  estimate  the  amount  of  sickness  which  may  be 
prevented  thereby,  aside  from  the  individual  comfort  which 
is  sure  to  result  to  such  as  may  be  brought  to  enjoy  this 
very  necessary  measure.  We  do  not  care  at  present  to 
speak  of  the  details  of  the  plan  ;  these  are  calculated  to 
take  care  of  themselves  when  once  the  soundness  of  the 
principles  are  fully  appreciated  by  the  authorities.  It  is 
pre-eminently  a  subject  which  deserves  the  attention  of 
the  civic  authorities,  and  it  is  to  be  hoped  that  his 
Honor  the  Mayor  and  the  Board  of  Aldermen  will  give 
some  direct  and  practical  turn  to  the  suggestion.  The 
medical  profession  can  be  counted  as  a  unit  in  favor  of 
it  In  fact,  we  fail  to  see  how  any  argument  can  be 
used  against  it,  except  the  comparatively  trivial  one  of 
the  expenditure  of  a  small  amount  of  money  with  a  little 


trouble  in  the  necessary  organization.  It  is,  however, 
one  thing  to  say  what  the  poor  should  do,  but  another 
thing  to  help  them  in  doing  it  The  end  to  be  attained 
by  keeping  them  clean  justifies  itself  beyond  argument, 
and,  fortunately,  the  means  are  easy  of  adoption  and 
comparatively  inexpensive. 

^ettTB  of  tlie  WSi6zk. 

American  Gynecological  Society, — By  the  omis- 
sion of  two  words  in  the  transmission  of  our  telegraphic 
report,  it  was  made  to  appear  that  the  President's  ad- 
dress was  not  delivered.  It  should  have  read,  was  post- 
poned un/il  tO'day  (Thursday)  on  account  of  sickness. 

On  Thursday  morning  Dr.  Albert  H.  Smith,  of  Phila- 
delphia, delivered  the  President's  address,  entitled,  '*The 
Present  Aspect  of  the  Puerperal  Diseases,*'  in  which  he 
reviewed  the  literature,  the  theoretical,  and  the  clinical 
aspects  of  the  subject,  and  then  devoted  considerable 
space  to  criticisms  on  the  germ  theory  of  the  diseases  as 
set  forth  by  Pasteur. 

Malarial  HiEMATURiA  and  Pernicious  Intermit- 
tent Fever. — Dr.  Thomas  J.  Moore,  of  Richmond,  Va., 
desires  us  to  make  some  slight  changes  in  the  report  of  his 
remarks  on  malarial  fever  before  the  Medical  Society  of 
Virginia,  at  its  late  session  (see  The  Medical  Record, 
September  20, 1884,  p.  328).  He  did  not  say  that  he  had 
frequently  met  with  cases  of  malarial  haematuria  in  North 
Carolina,  where  he  had  practised,  but  in  the  practice  of 
his  brother  practitioners  in  the  northern  part  of  Ala- 
bama.  He  is  made,  in  the  report,  to  say  that  he  uses 
quinine  hypodermically  in  ordinary  malarial  fever,  where- 
as he  said  that  he  was  in  the  habit  of  using  the  salt  in 
that  manner  in  cases  oi  pernicious  intermittent  fever. 

The  Examination  to  Fill  the  Position  on  the 
House  Staff  of  the  Presbyterian  Hospital  will  be 
held  at  the  Hospital  on  November  3d,  at  2.30  p.m.  For 
particulars  address  Rev.  Thomas  G.  Wall,  Superinten- 
dent 

Remedies  for  Cholera. — M.  Vulpian  has  made  a 
report  to  the  Academie  des  Sciences  upon  two  hundred 
and  fifty  remedies  for  cholera,  which  have  been  sent  by 
persons  desiring  to  obtain  the  Bryant  prize  of  100,000 
francs.  Some  of  the  discoveries  modestly  ask  that  they 
may  be  sent  to  Marseilles  in  order  to  test  their  remedies. 

The  Washington  International  Medical  Con- 
GRESS.^-The  Committee  on  Organization  of  this  Congress 
has  been  constituted  as  follows :  Drs.  Austin  Flint,  of 
New  York  ;  I.  Minis  Hayes,  of  Philadelphia ;  Lewis  A. 
Sayre,  of  New  York ;  Christopher  Johnston,  of  Baltimore ; 
George  J.  Engelmann,  of  St.  Louis ;  J.  S.  Brown,  U.  S. 
Navy,  and  J.  S.  Billings,  U.  S.  Army. 

Significant. — ^The  British  Journal  of  Hotnceopaihyy 
one  of  the  oldest  journals  of  its  class,  will  cease  to  be 
published  after  this  year. 

An  Investigation  by  the  New  York  State  Board 
of  Health. — The  New  York  State  Board  of  Health  is 
said  to  be  about  to  undertake  a  collective  investigation 
upon  the  question  as  to  when  a  patient  convalescent 
from  an  infectious  disease  ceases  to  be  capable  of  con- 
veying the  infection. 


4IO 


THE   MEDICAL  RECORD. 


[October  ii,  1884, 


The  Vermont  State  Medical  Society  holds  its 
seventy-first  annual  meeting  at  Montpelier  on  October 
15  and  16,  1884,  The  presiding  officer  is  Dr.  S,  S. 
Clark,  of  St  Albans,  Papers  are  to  be  read  upon  "  Diph- 
theria," "Rupture  of  the  Uterus,"  "Laceration  of  the  Cer- 
vix,"  and  other  subjects.  Dr.  J.  S.  Richmond,  of  Wood- 
stock, Vt,  is  Secretary. 

Responsibility  for  Payment  of  a  Consulting 
Physician. — A  test  case,  says  the  Canada  Lancet^  was 
recently  tried  in  Belleville,  Ontario,  to  determine  whether 
or  not  a  patient  is  liable  for  the  fees  of  a  medical  man 
who  is  called  by  a  friend  or  relative.  In  this  case  the 
brother  of  the  patient  summoned  the  consulting  physician, 
who  assisted  in  the  amputation  of  a  finger.  The  patient 
refused  to  pay  the  consulting  physician,  on  the  ground 
that  he  had  not  engaged  him,  and  told  him  to  look  to  the 
attending  physician  for  his  fee.  The  judge  who  tried  the 
case  ordered  a  non-suit,  holding  that  the  patient  was 
responsible  only  to  the  physician  he  engaged. 

Mr.  Lawson  Tait,  while  at  Hamilton,  Ontario,  opened 
the  abdomen  for  supposed  gall-stones  and  found  car- 
cinoma instead. 

Infectious  Disease  may  Render  a  Lease  Void. 
— A  decision  was  recently  rendered  in  England  by  Mr. 
Justice  Field  in  a  case  where  a  claim  was  made  for  rent 
for  furnished  apartments  for  the  term  of  the  lease,  the  les- 
sor refusing  to  occupy  the  house  because,  after  the  lease 
was  made  and  before  the  lessee  vacated  the  apartments, 
a  case  of  an  infectious  disease  appeared  in  [the  rooms. 
The  defendant  claimed  that  the  existence  of  a  contagious 
disease  in  a  house  rendered  it  uninhabitable,  and  the 
justice  rendered  a  decision  favorable  to  the  defendant 

The  New  York  Neurological  Society  held  its  first 
regular  meeting  for  the  season,  on  October  6th.  A  paper 
on  " Gastric  Neurasthenia"  was  read  by  Dr.  L.  Weber, and 
one  on  "  Pseudo-bulbar  Paralysis "  by  Dr,  W.  Browning. 

The  Medical  Section  of  the  French  Congress 
FOR  THE  Advancement  of  Science. — Among  papers  of 
interest  read  before  this  section,  was  one  by  M.  Chaumier 
on  "  The  Epidemic  and  Contagious  Nature  of  Acute  Pneu- 
monia." The  author  thought  that  pneumonia  was  a  con- 
stitutional infectious  endemic  disease,  sometimes,  though 
rarely,  propagated  by  direct  contagion.  It  had  a  germ 
which  could  retain  vitality  more  or  less  long  in  dwelling- 
houses.  M.  Chaumier  thought  it  wrong  to  poison  with 
drugs  persons  already  poisoned  with  disease,  and  advo- 
cated the  treatment  of  pneumonia  by  baths  alone. 

M.  August  Ollivier  read  a  paper  upon  the  "  Pathogeny 
of  Herpetic  Angina,"  in  which  he  sought  to  establish  the 
view  that  it  was  a  neurosis  generally  of  the  middle  branch 
of  the  trigeminus. 

M.  Bessette  urged  the  use  of  the  thermocautery  to 
the  entire  exclusion  of  the  scalpel  in  the  treatment  of 
spontaneous  gangrene. 

The  Cholera. — It  is  seventeen  weeks  since  the  chol- 
era first  appeared  in  France  and  over  eleven  weeks  since 
it  appeared  in  Italy.  The  deaths  from  the  disease  in 
France  have  averaged  about  375  per  week,  while  in  Italy 
the  average  has  been  1,000  a  week.  A  Roman  paper 
estimates  the  total  number  of  deaths  up  to  October  ist 
at  10,800.     There  is  every  indication  that  the  force  of 


the  epidemic  is  now  spent,  in  Italy  as  well  as  in  France 
and  Spain.     The  total  number  of  deaths  from  cholera  in 
Italy  on  October  7th  was  only  44,  in  France  8,  in  Spain 
I.     A  correspondent  of  the  New  York  Times  writes  that 
the  mastery  of  the  plague  in  Genoa  is  really  the  first  fine 
medical  feature  of  the  whole  siege.     Immediately  after 
the  pest  broke  out  with  virulence  in  that  city,  a  fortnighl 
ago,  the  authorities  had  the  water  supply  analyzed,  and 
they  discovered  that  of  the  three  sources  of  supply,  that 
of  the   Nicolai   Company  was  awful.     The  municipal 
works'  supply  was  pretty  bad,  and  that  of  the  Gerzenti 
Company  was  pure.     Immense  and  costly  efforts  were 
promptly  made  to  shut  off  the  first  two  sources  and  to  turn 
the  latter  water  into  all  the  pipes.     An  immediate  im- 
provement  was  noticed,  and  the  mortality  declined  after 
eight  days,  instead  of  advancing  for  weeks,  as  has  usually 
been  the  case.     We  learn  by  cable  also  that  the  commis- 
sion sent  to  Marseilles  has  made  an  elaborate  report  of 
many  experiments  with  microbes,  all  of  which  were  failures, 
and  that  Dr.  Klein  has  shown  contempt  for  the  microbe 
theory  by  swallowing  a  quantity  of  bacilli  without  harm- 
ful result.    The  Marseilles  commission  found  it  could 
mathematically  trace  a  cholera  patient's  condition  by  an 
hourly  examination  of  the  blood,  the  healthy  globules  re- 
maining stationary  and  the  unhealthy  ones  flomng  be- 
tween columns  formed  by  others  and  taking  them  gradu- 
ally off  until  the  column  is  ruptured.     The  commission 
affirms  that  cholera  is  not  contagious,  and  it  concludes 
that  while  we  know  better  than  our  predecessors  what 
the  cholera  is  not,  we  do  not  know  what  it  is. 

The  Acad^mie  de  MtoECiNE  met  September  9th. 
M.  Morel  read  a  paper  upon  the  ''  Cause  of  the  Normal 
Evening  Rise  of  Temperature."  This  was  due  to  three 
things  :  food,  light,  and  exercise,  of  which  food  was  the 
chief  factor.  Animals  fed  during  the  night  had  the  nor- 
mal rise  of  temperature  in  the  morning.  M.  Dujardin- 
Beaumetz  reported  the  results  of  his  study  of  disinfect- 
ants.  He  had  reached  the  conclusion  that  sulphurous 
acid  is  the  most  efficient  and  convenient  germicide.  To 
obviate  the  objection  that  it  attacks  metals  he  had  re- 
course to  sulphurous  acid  made  from  liquid  sulphurous 
acid  by  the  method  of  Raoul  Pictet 

Medicine  Takes  Curious  Freaks  in  some  of  the 
States  beyond  the  Father  of  Waters.  In  Nebraska,  for 
example,  there  is  a  State  University  with  a  Medical  De- 
partment. Said  Medical  Department  has  been  taken 
possession  of  by  certain  eclectics,  who  naturally  have 
started  a  medical  organ,  the  Nebraska  Medical  JoumdL 
The  State  evidently  supports  the  Department,  for  we  are 
told  that  tuition  is  free  and  expenses  light.  We  are 
pleased  to  observe  also  that  this  free  Medical  Depart- 
ment has  joined  the  cause  of  higher  education,  and  will 
hereafter  require  attendance  upon  three  courses  instead 
of  two.  Meanwhile  the  organ  is  publishing  various  dis- 
cussions as  to  whether  electricity  is  the  cause  of  the 
heart's  movements. 

Mistakes  in  Words. — A  Philadelphia  contemporary 
publishes  a  newspaper  clipping  concerning  the  word 
"^microbe."  This  word,  it  states,  was  coined  by  M, 
Charles  S^dillot,  of  Strasbourg,  in  1878.  The  truth  is, 
however,  that  Professor  Pacini  used  the  word  "  micro- 
bio  "in  1854,  applying  it  to  a  micro-organism  of  cholera. 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


411 


Valuable  Articles  Stolen  from  Physicians'  Of- 
fiCKS.— At  the  Tenth  Police  Precinct  Station-house, 
Brooklyn,  N.  Y.,  there  are  several  valuable  articles  re- 
cently stolen  by  an  office-thief,  whose  operations  were 
very  extensive  in  New  York.  These  articles  consist  of 
microscopes,  instruments,  umbrellas,  clothing,  etc,  still 
unclaimed,  and  which  evidently  belong  to  New  York 
physicians.  The  captain  is  anxious  that  they  be  identi- 
fied and  taken  away.  The  station-house  is  at  the  comer 
of  Flatbush  and  Sixth  Avenues,  Brooklyn. 

Subscriptions  Asked  for  a  Statue  to  Dr.  Joseph 
GuiSLAiN. — We  publish  with  pleasure  the  following  notice 
sent  to  us  by  Dr.  Lewis  D.  Mason,  of  Brooklyn  :  "  An 
effort  is  being  made  to  secure  subscriptions  for  the  erec- 
tion of  a  statue  to  Dr.  Joseph  Guislain.  The  members 
of  the  Society  of  Mental  Medicine,  of  Belgium,  are  ac- 
tively interested  in  promoting  this  object,  and  desire  that 
all  specialists  in  this  department  of  medicine  have  an 
opportunity  to  subscribe,  and  that  the  statue  represent 
the  combined  subscriptions  of  the  specialists  in  mental 
diseases  of  the  world,  rather  than  of  any  given  district. 
To  this  end,  subscriptions  have  been  received  from  Eng- 
land, France,  Russia,  Germany,  Italy,  Holland,  and 
Sweden,  in  sums  varying  from  five,  to  twenty-five  ^ancs. 
The  United  States,  as  yet,  is  not  represented.  We  hope 
the  subscriptions  from  America  toward  the  erection  of 
this  statue  will  compare  favorably  with  those  of  other 
countries.  Subscriptions  may  be  sent  to  Dr.  B.  C.  Ingels, 
MMicin  de  THospice-Guislain  i  Gaud,  Belgium.  List 
of  acknowledgments  will  be  sent  to  subscribers." 

The  Limits  of  Legitimate  Advertising. — We  com- 
mend  to  our  readers'  attention  the  following  from  the 
Iowa  Afedual  Monthly,  The  limitations  which  are  here 
suggested  contrast  strongly  with  the  sordid  and  commer- 
cial view  which  allows  the  unlimited  distribution  of  pro- 
fessional cards  with  the'  specialty  obliquely  indicated 
thereon.  Says  the  Monthly :  "  Is  there  such  a  thing  as 
legitimate  advertising,  that  the  physician  may  u^e  with- 
out violating  the  spirit  of  the  Code  ?  We  would  answer 
unqualifiedly,  yes,  and  that  its  dimensions  begin  with  a 
good  education,  gentlemanly  conduct,  social  qualities,  in- 
dustry,  and  end  with  the  moral  eflfect  in  the  community 
of  his  good  deeds,  distributed  by  word  of  mouth,  from 
his  friends.  This  mode  of  advertising,  together  with  that 
invaluable  quality,  tact  or  good  judgment,  will  always 
bring  success." 

Objects  and  Membership  of  the  American  Acad- 
emy OF  Medicine. — We  have  been  requested  by  Dr. 
Richard  J.  Dunglison,  Secretary,  to  announce  the  objects 
aimed  at  by  the  American  Academy  of  Medicine,  and 
also  the  qualifications  necessary  for  membership.  The 
Academy  is  growing  yearly  in  members  and  influence, 
but  it  is  desired  that  it  embrace  in  its  membership  all  the 
physicians  in  the  country  qualified  therefor.  The  Con- 
stitution  says  that  the  objects  of  the  Academy  shall  be  : 
I.  To  bring  those  who  are  Alumni  of  Classical,  Scien- 
tific, and  Medical  Schools  into  closer  relations  with  each 
other.  2.  To  encourage  young  men  to  pursue  regular 
courses  of  study  in  classical  and  scientific  institutions 
before  entering  upon  the  study  of  medicine.  3.  To  ex- 
tend the  bounds  of  medical  science,  to  elevate  the  pro- 
fession, to  relieve  human  suffering,  and  to  prevent  dis- 


ease. The  Membership  of  the  Academy  shall  consist  of 
Fellows  and  Honorary  Members.  The  Fellows  shall  be 
Alumni  of  respectable  institutions  of  learning,  having 
received  therefrom  :  i.  The  degree  of  Bachelor  of  Arts, 
or  Master  of  Arts,  after  a  systematic  course  of  study, 
preparatory  and  collegiate.  2.  The  degree  of  Doctor  of 
Medicine,  after  a  regular  course  of  study,  not  less  than 
three  years,  under  the  direction  and  instruction  of  pre- 
ceptors and  professors.  3.  When  a  candidate  is  an 
alumnus  of  a  foreign  institution  not  granting  the  degree 
of  Bachelor  of  Arts  or  Master  of  Arts,  a  certificate  or 
certificates,  which  shall  be  considered  as  equivalent  by 
the  Council  an4  Academy,  may  be  accepted  in  lieu 
thereof,  provided  he  shall  have  subsequently  received  the 
degree  of  Doctor  of  Medicine.  4.  The  Fellows  shall 
also  have  had  an  experience  of  three  years  in  the  Prac- 
tice of  Medicine,  in  one  or  more  of  its  recognized  depart- 
ments, and  shall  have  a  good  moral  and  professional 
character. 

The  French  Association  for  the  Advancement 
OF  Science. — This  association,  which  now  numbers  four 
thousand  members,  held  its  annual  meeting  at  Blois,  be- 
ginning September  4th.  It  has  a  Medical  Section  which 
is,  we  believe,  the  nearest  approach  to  a  National  Medi- 
cal Society  that  France  possesses.  The  meetings  of  this 
Section  have  not  heretofore  been  productive  of  any  very 
valuable  work,  and  have  not  attracted  many  of  the  leading 
members  of  the  profession.  The  last  meeting  at  BloiS| 
however,  seems  to  have  been  rather  more  notable.  It 
was  presided  over  by  M.  Nicaise,  and  among  those  pres- 
ent were  MM.  OUivier,  Bouchard,  and  Vemeuil. 

The  New  York  City  Board  of  Health. — ^The 
Sanitary  Engineer  censures  our  city  Board  of  Health  on 
account  of  its  inefficient  action  in  cleaning  out  the 
"  slums."  The  practice  of  dealing  with  these  places  by 
turning  the  wretched  inhabitants  temporarily  into  the 
streets  and  then  ''squirting  copperas-water  over  the 
filth,"  is  denounced  as  a  weak  and  useless  measure. 
The  Sanitary  Engineer  believes  that  all  these  rookeries 
should  be  torn  down,  if  we  do  not  wish  the  cholera  here. 

The  Nebraska  State  Medical  Society  and  Pre- 
liminary Education. — We  learn  from  The  J^rnal  of 
the  American  Medical  Association  that  the  Nebraska 
State  Medical  Society  has  made  arrangements  for  secur- 
ing a  preliminary  education  to  all  persons  intending  to 
study  medicine  with  physicians  of  the  State.  No  member 
of  the  Society  will  accept  a  student  of  medicine  unless 
he  has  given  evidence  of  having  a  certain  amount  of 
preliminary  education.  This  is  a  step  that  has  abready 
been  taken  by  some  smaller  societies  and  we  trust  the 
example  will  continue  to  be  imitated,  and  the  practice 
honestly  carried  out.  Dr.  Davis  says  :  **  We  have  seen 
parties,  who  in  medical  society  meetings  and  addresses 
would  advocate  the  most  rigid  exaction  of  a  fair  standard 
of  general  education,  take  students  into  their  own  offices 
who  had  not  even  a  respectable  common  or  district 
school  education,  and  then  advise  them  to  attend  medical 
colleges  where  not  only  no  standard  of  general  educa- 
tion was  required,  but  where  a  diploma  could  be  obtained 
for  an  expenditure  of  the  smallest  amount  of  [time  and 
money." 


412 


THE  MEDICAL  RECORD. 


[October  ii.  1884. 


The  International  Otological  Congress. — ^The 
Third  International  Otological  Congress  was  held  at  Basel, 
Switzerland,  from  the  ist  to  the  5th  of  September,  under 
the  presidency  of  Dr.  A.  Burckhardt-Merian,  of  Basel.  We 
learn  from  The  British  Medical  Journal  that  the  pro- 
ceedings were  opened  on  Monday  at  the  hall  of  the 
University,  by  addresses  from  Dr.  Sapolini,  of  Milan,  the 
retiring  president,  and  Dr.  Burckhardt-Merian,  the  presi- 
dent-elect. Addresses  of  welcome  to  the  town  of  Basel 
were  delivered  by  Counsellor  Schenck,  on  the  part  of  the 
Swiss  Federation,  and  by  a  delegate  from  the  Canton  of 
Basel.  A  breakfast,  given  by  the  Swiss  surgeons  to  the 
members  of  the  Congress,  followed.  \Oxi  Wednesday 
the  members  of  the  Congress  were  entertained  at  a 
banquet.  During  the  three  following  days  about  forty 
papers  were  read,  and  demonstrations  were  given  on  sub- 
jects bearing  on  otological  science,  all  of  a  most  in- 
teresting, instructive,  and  original  nature.  The  principal 
contributors  were  Politzer,  of  Vienna ;  Moos,  of  Heidel- 
berg ;  Guye,  of  Amsterdam  ;  Sapolini,  of  Milan  ;  Gelle, 
of  Paris  ;  His,  of  Leipzig ;  Hartmann,  of  Vienna ;  Lowen- 
berg,  of  Paris ;  Kuhn,  of  Strasburg ;  Albrecht  and  Del- 
stanche,  of  Brussels  ;  and  Pritchard,  of  London.  It  has 
been  arranged  that  the  next  Otological  Congress  be  held 
in  Brussels  in  1888  ;  and  an  organizing  committee  has 
been  nominated,  Dr.  Urban  Pritchard  representing  Eng* 
land. 

Dr.  Thaddeus  Johnson  has  resigned  the  Chair  of 
Surgery  in  the  Southern  Medical  College,  on  account  of 
his  health.  He  is  succeeded  by  Dr.  J.  McF.  Gaston, 
formerly  of  Columbia,  S.  C. 

A  Text  Book  of  Practical  Medicine  :  Designed  for 
the  Use  of  Students  and  Practitioners  of  Medicine.  By 
Alfred  I*  Loomis,  M.D.,  LL.D.,  Professor  of  Pathol- 
ogy and  Practical  Medicine  in  the  Medical  Depart- 
ment of  the  University  of  the  City  of  New  York,  Visit- 
ing Physician  to  Bellevue  Hospital,  etc.  With  two 
hundred  and  eleven  illustrations.  8vo,  pp.  1,102. 
New  York :  William  Wood  &  Co.     1884. 

The  popularity  of  Professor  Loomis  as  a  medical  teacher 
will  of  itsi^lf  do  a  great  deal  toward  making  this  book  a 
success.  But  it  need  not  rely  on  this.  Independent  of 
the  author^s  reputation  the  volume  can  speak  for  itself, 
as  a  comprehensive  and  practical  treatise  on  general 
medicine.  The  first  thing  which  impresses  the  reader  is 
the  systematic  arrangement  of  the  various  diseases  dis- 
cussed. In  so  far,  the  author  stamps  his  work  with  the 
results  of  his  experience  as  a  clinician.  His  aim  appar- 
ently is  to  draw  the  outline  of  general  principles  with  a 
rigidity  and  distinctness  which  admits  of  no  question. 
This  is,  however,  rather  a  virtue  than  a  fault,  considering 
the  aim  of  the  book.  It  brings  out  the  strong  individu- 
ality of  the  author.  It  is  a  positive  book  from  bepn- 
ning  to  end,  bringing  out  the  strong  views  of  a  practical 
man.  The  style  is  terse  and  perspicuous,  the  descrip- 
tions of  diseases  and  the  indications  for  treatment  are 
direct,  practical,  and  force  upon  the  reader  the  convic- 
tion that  the  author  not  only  understands  his  subject 
in  all  its  bearings,  but  has  the  faculty  of  taking  others  with 
him. 

While  it  may  be  difficult  to  conceive  ^he  possibility  of 
originality  in  a  work  like  this,  there  is  enough  of  such  an 
element  about  it,  in  arrangement  and  general  treatment, 
to  make  it  different  from  any  of  its  kind,  and  propor- 


tionately valuable.  Dr.  Loomis  is  particularly  happy  in 
making  clear  the  indications  for  treatment  of  the  different 
diseases  as  based  upon  pathological  conditions.  He  is 
seen  at  his  best  in  his  discussion  of  fevers  and  chest  and 
kidney  diseases.  It  is  safe  to  say  that  the  chapters  on 
these  subjects  have  no  equal  for  practical  worth  in 
any  language.  His  divisions  are  natural,  scientifically 
systematic,  and  thoroughly  practical,  really  leaving 
nothing  to  be  desired  on  the  part  of  the  learner  who 
wishes  for  a  broad  and  solid  foundation,  upon  which  he 
can  base  his  facts  of  past  and  future  experiences.  The 
difficult  subject  of  auscultation  is  made  strikingly  simple 
not  only  by  word  description,  but  by  means  of  diagrammatic 
representations.  The  latter  are  of  the  greatest  value  to 
the  student  in  making  out  the  relation  of  the  auscultatory 
signs  to  the  different  pathological  changes  in  the  lungs 
and  heart.  It  is  difficult  to  conceive  how  they  could  be 
indicated  more  satisfactorily. 

The  chapters  on  fevers  are,  as  already  intimated,  of 
great  value.  Typhoid  fever  receives  the  attention  which 
its  great  frequency  of  occurrence  demands.  There  is 
scarcely  any  acute  disease  the  treatment  of  which  gives  the 
practitioner  more  anxiety  than  this.  There  are  so  many 
circumstances  to  be  taken  into  account,  and  so  many 
conditions  to  be  fulfilled,  that  he  cannot  study  them  too 
thoroughly,  or  cannot  be  too  well  prepared  for  emergen- 
cies. Professor  Loomis  treats  this  disease  as  he  does  all 
others,  from  a  clinical  standpoint,  and  the  rules  which  he 
lays  (k>wn  are  eminently  safe,  and  will  commend  them- 
selves accordingly  to  the  good  sense  and  experience  of 
every  one  who  has  seen  much  practice  in  that  line. 
These  remarks  will  be  found  to  apply  specially  to 
reduction  of  temperature  by  cold  baths  and  by  quinine. 
The  latter  in  large  doses  is  a  favorite  with  the  author, 
and  his  reasons  for  the  practice  are  very  intelligibly 
given. 

The  division  of  fevers  is  the  same  as  that  adopted  by 
most  authors,  with  the  exception  that  the  typho-malarial 
type  is  treated  under  the  head  of  continued  malarial 
fever.  The  author  believes  that  the  latter  is  caused  by 
the  combined  influence  of  a  malarial  and  a  septic  ele- 
ment. His  treatment,  however,  does  not  differ  essen- 
tially from  that  advocated  by  observers  who  first  studied 
the  disease  during  the  late  war.  We  are  inclined  to  be- 
lieve that  the  new  name  is  a  good  one,  and  will  be  gen- 
erally adopted  as  best  expressing  the  general  features  of 
the  disease. 

Bright's  diseases  are  treated  of  under  three  leading 
heads  :  First,  the  form  in  which  the  morbid*  changes 
commence  in  the  uriniferous  tubules,  designated  par- 
enchymatous nephritis ;  second,  the  form  in  which  the 
change  commences  in  the  intertubular  tissue,  the  cir- 
rhotic kidney  ;  and  third,  the  variety  in  which  the  blood- 
vessels are  first  diseased,  viz.,  the  amyloid  kidney.  This 
division  is  simple  and  founded  on  advanced  pathology. 
While  speaking  of  this  disease  we  wish  to  refer  to  die 
admirable  rules  laid  down  for  treatment,  and  congratu- 
late the  author  on  the  masterly  manner  in  which  he  has 
simplified  the  whole  subject. 

The  figures  showing  microscopical  changes  of  organs 
are  admirably  drawn,  and  were  specially  prepared  for  the 
work  by  Dr.  M.  N.  Miller,  of  the  University  Laboratory. 
Of  these  there  is  a  large  number,  giving  all  the  leading 
pathological  changes  in  the  tissues  of  the  different  in- 
ternal organs. 

In  summing  up  our  conclusions  in  regard  to  the  book 
as  a  whole,  we  repeat  that  it  is  the  best  of  its  kind  and  is 
destined  to  be  the  most  popular  work  on  practical  medi- 
cine yet  published  It  is  a  matter  for  great  congratulation 
that  by  means  of  his  admirable  book  the  distinguished 
author  can  now  reach  thousands  who,  unfortunately  for 
them,  have  not  had  the  opportunity  of  enjoying  his 
teaching  in  the  class-room  or  hospital  ward,  and  learn- 
ing those  methods  of  diagnosis  and  treatment  which  have 
tended  to  make  him  a  successful  practitioner  in  every 
sense  of  ♦^^^e  term. 


October  ii,  1884,] 


THE  MEDICAL  RECORD. 


413 


^epovts  ot  S^acUtUs. 


PRACTITIONERS'  SOCIETY  OF   NEW  YORK. 

Stated  Meeting,  October  3,  1884. 

Dr.  a.  Brayton  Ball,  President,  in  the  Chair. 

Dr.  James  B.  Hunter  read  a  paper  (see  page  397)  en- 
titled 

SOME  POINTS  IN  THE  THERAPEUTIC  APPLICATION  OF  HEAT 
AND    COLD. 

Dr.  George  F.  Shrady  was  ready  to  endorse  Dr. 
Hunter  in  his  remarks  on  the  relative  value  of  hot  and 
cold  applications  in  the  treatment  of  surgical  cases. 
There  was  no  question  in  his  mind  as  to  the  value  of  the 
cold  coil,  as  recommended  by  the  author  of  the  paper,  in 
the  treatment  of  traumatic  peritonitis.  In  such  cases 
cold  was  used  as  a  preventive  or  arrester  of  a  formidable 
and  rapidly  spreading  inflammation.  In  general,  how- 
ever, in  the  treatment  of  surgical  injuries,  when  an  at- 
tempt was  made  to  fulfil  these  indications,  there  was  often 
a  failure,  for  the  reason  that  the  cases  were  not  seen  suf- 
ficiently early.  This  was  certainly  so  in  hospital  practice. 
And  from  other  contra-indications  these  applications 
were  frequently  painful  to  the  patients,  especially  those 
who  were  suffering  from  synovitis  and  sprains.  Conse- 
quently he  was  getting  into  the  habit  of  using  hot  appli- 
cations in  preference,  particularly  for  joint  sprains,  ac- 
companying such  treatment  with  rest  and  following  it 
with  a  firmly  supporting  bandage.  In  many  cases  of 
recent  sprain  he  used  nothing  but  the  bandage  and  rest. 
When  inflammation  was  fairly  under  way  and  incapable 
of  arrest,  hot  applications  were  indicated;  even  in  trau- 
matic peritonitis,  especially  if  these  were  combined  with 
the  internal  administration  of  opium  in  full  doses. 

In  regard  to  the  application  of  cloths  soaked  in  hot 
water  to  oozing  wounds  there  could  be  no  doubt  of  its 
value,  nor  of  that  of  the  injection  of  hot  water  into 
stumps  in  a  like  condition.  Rubber  bags  filled  with  hot 
water  formed  a  very  useful  means  of  marking  hot  applicar 
tions  to  limited  inflammatorv  troubles. 

Dr.  Samuel  Sexton  saia  that  the  paper  called  to  his 
mind  an  early  experience  in  the  use  of  hot  water,  which 
had  started  him  to  using  it  a  great  deal.  In  1870  he  met 
a  gentleman  in  the  wash-room  of  the  Union  League  who 
was  unsuccessfully  trying  to  stop  a  severe  nose-bleed  by 
the  use  of  cold  water.  Dr.  Sexton  recommended  him  to 
snuff  hot  water  up  the  nose.  This  was  done  and  the  at- 
tack stopped  almost  instantly.  Since  then  the  speaker 
had  used  hot  water  as  a  haemostatic  in  all  cases,  after  re- 
moving polypi ;  also  as  a  gargle  after  tonsillotomy. 

With  regard  to  the  use  of  cold,  in  the  early  years  of 
his  practice  he  had  used  freezing  applications  in  the  am- 
putation of  fingers,  as  a  local  anaesthetic.  They  had 
prevented  suflfering  and  acted  very  well. 

Dr.  a.  a.  Smith  had  used  both  rubber  and 

lead  coils  in  pyrexia. 

In  some  cases  of  typhoid  fever,  with  a  temperature  of 
105°  to  105^®  F.,  a  single  application  of  the  lead  coil 
had  reduced  the  temperature  to  below  100°  F.  The 
coil  used  had  been  considerably  smaller  than  those  shown 
hy  Dr.  Hunter.  It  would  not  only  reduce  the  tempera- 
ture but  keep  it  down.  In  one  case  of  typhoid  fever  the 
coil  had  been  kept  on  continuously  for  nine  days,  the 
temperature  being  kept  below  100". 

Dr.  Smith  had  noticed  that  the  pulse  was  not  always 
reduced  in  rapidity  correspondingly  with  the  temperature, 
and  he  thought  that,  as  a  rule,  when  the  temperature  is 
reduced  rapidly  the  pulse  is  reduced  in  a  much  less  de- 
gree. 

He  had  been  for  a  long  time  a  very  strong  believer  in 
the  reduction  of  temperature  by  cold  as  a  therapeutic 
measure  in  the  pyrexiae ;  but  he  also  believed  that  it  was 


capable  of  doing  much  harm.  He  did  not  believe  in  the 
heroic  application  of  cold  in  typhoid  fever  after  the  tenth 
or  fourteenth  day,  or  when  there  was  a  tendency  to  heart 
failure,  for  it  might  then  cause  nervous  shock.  tHe  believed 
that  the  applications  of  cold  acted  in  much  the  same  way 
as  the  various  antipyretics,  referring  especially  to 

KAIRIN  and   ANTIPYRIN. 

These  will  reduce  temperature,  but  they  also  reduce  the 
force  of  the  pulse.  The  new  agent,  antipyrin,  reduces 
temperature  very  powerfully,  but  it  weakens  the  heart 
also.  The  speaker  doubted  if  Americans  had  the  con- 
stitutions which  would  stand  the  powerful  antipyretic 
measures  to  which  the  more  stolid  Germans  are  sub- 
jected. He  felt,  therefore,  that  the  safest  means  of  ap- 
plying cold  was  the 

kibbee's  cot. 

He  had  been  much  pleased,  however,  with  the  action  of 
the  coils,  and  they  seemed  to  furnish  a  safe  way  of  apply- 
ing cold.  The  speaker  recalled  the  introduction  of  cold 
applications  in  fever  at  Bellevue  Hospital,  in  1870-71. 
The  impression  received  then  was  that  the  application  of 
cold  locally  in  the  form  of  ice-bags,  in  pneumonia,  seemed 
to  increase  the  tendency  to  involve  new  lung  tissue. 

Dr.  Kinnicutt  had  found  that  the  most  satisfactory  way 
of  applying  cold  in  typhoid  fever  was  by  means  of  the 
Kibbee  cot.  He  had  given  it  a  very  thorough  trial  in  St. 
Luke's  Hospital.  He  had  succeeded  in  obtaining  all  the 
good  results  of  the  full-length  bath  without  the  discom- 
fort to  the  patient  of  the  latter  and  the  increased  labor 
entailed  upon  the  attendants.  A  large  receptacle  for  the 
water  was  placed  upon  a  stand  above  the  patient's  head ; 
a  rubber  tube  was  attached,  ending  in  a  numerously 
perforated  nozzle.  The  patient,  uncovered  or  covered 
simply  with  a  sheet,  was  then  continuously  sprinkled 
from  head  to  foot,  for  a  time  corresponding  to  that 
usually  employed  in  giving  the  full-length  bath. 

Dr.  Kinnicutt*s  experience  differed  from  Dr.  Smith's 
in  that,  as  a  rule,  he  had  found,  by  either  the  full-length 
bath  or  by  the  application  of  cold  by  means  of  Kibbee'scot, 
with  a  reduction  of  temperature  there  had  been  a  corre- 
sponding reduction  in  the  frequency  of  the  heart's  action. 
Was  it  not  possible  that  the  coil  acted  in  a  somewhat 
diflerent  way  in  lowering  temperature  from  cold  water 
bathing  ? 

Dr.  a.  Brayton  Ball  said,  that  when  he  went  upon 
his  service  at  Bellevue  Hospital,  he  had  been  told  that 
the  cold  coils  had  been  tried  in  typhoid  fever,  and  that 
they  had  failed.  He,  therefore,  had  not  tried  to  use  them. 
Dr.  Fordyce  Barker  said  that  he  had  been  studying 
clinically  the  subject  of  the  antipyretic  use  of  cold  ever 
since  Dr.  Wilson  Fox's  paper  appeared  on  the  "  Use  of 
Heat  and  Cold  in  Hyperpyrexia."  By  hyperpyrexia 
he  meant  a  condition  in  which  the  temperature  rose  to 
107°  or  112°  F.  This  was  an  essential  fever  and  a  rare 
one.     He  had  seen  but  very  few  cases. 

He  had  thought  that  in  the  use  of  cold  as  an  antipy- 
retic one  point  had  been  overlooked  in  practice,  and 
that  was  the  looking  at  the  pyrexia  as  the  essential  dis- 
ease, instead  of  regarding  it  as  one  of  the,  perhaps,  inci- 
dental symptoms,  which  might  or  might  not  demand 
treatment. 

Two  or  three  years  ago  there  beean  to  be  a  great  deal 
of  interest  in  regard  to  the  use  of  cold  in  arresting  or 
preventing  and  even  curing  peritonitis.  That  treatment 
was  most  enthusiastically  advocated  by  several  surgeons, 
notably  by  Dr.  Thomas.  The  speaker,  however,  was 
obb'ged  to  say  that  he  had  reached  conclusions  in  some 
respects  quite  different  from  what  he  had  expected. 

He  was  not  certain  but  that  there  was  a  very  essential 
difference  between  surgical  peritonitis  and  idiopathic,  or 
what  he  would  call,  for  want  of  a  better  term, 

OBSTETRICAL  PERITONITIS. 

He  saw  quite  a  number  of  these  cases  treated  by  cold 
applications.     He  had  studied  them  with  a  perfectly  im- 


414 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


partial  mind,  and  he  had  been  disappointed  in  the  re- 
sults. In  many  cases  he  found  no  such  results  as  Dr. 
Thomas  and  others  had  claimed.  There  were  two  cases 
in  particular,  which  he  had  in  mind,  where  the  coil  had 
been  used  most  thoroughly.  At  first  its  influence  had 
been  to  reduce  the  temperature  and  pulse,  but  after  a 
time  the  temperature  ran  up  to  104°  or  105°  F.,  and  the 
pulse  became  quick,  while  associated  with  it  was  a  very 
bad  general  condition.  He  had  found  symptoms  of 
general  depression  and  impending  pneumonia  or  bron- 
chitis. The  whole  abdomen  was  pale,  the  capillary  cir- 
culation almost  arrested,  with  doubtless,  in  consequence, 
a  hypera^niia  of  the  deeper-seated  organs.  After  remov- 
ing the  coil  and  the  administration  of  stimulants,  and  ap- 
plication of  turpentine  to  the  abdomen,  the  most  marked 
improvement  occurred.  The  temperature  fell,  and  the 
pulse  became  slower  and  stronger. 

These  experiences  surprised  him,  because  he  had  pre- 
viously seen  a  remarkable  result  from  cold,  and  one 
which  led  him  to  expect  a  great  deal  from  its  use. 

Two  years  ago,  on  one  of  the  worst  nights  of  the 
winter,  he  was  summoned  to  see  a  lady  who  had  been 
taken  suddenly  very  ill.  She  had  been  to  the  opera  that 
evening,  and  after  it  was  over  had  been  obliged  to  stand 
in  the  doorway,  exposed  to  the  air,  while  waiting  for  her 
carriage.  She  was  menstruating  at  the  time.  The 
menses  stopped,  and  when  she  got  home  she  was  seized 
with  a  most  violent  and  prolonged  chill.  This  was 
followed  by  intense  pain  throughout  the  abdomen. 
Ginger  tea  was  given,  and  hot  applications  made,  but 
the  pain  went  on  increasing  until,  when  the  speaker  ar- 
rived, she  was  nearly  frantic.  The  patient  was  of  a 
self-possessed  and  calm  temperament,  but  suffering  such 
agony  that  she  could  hardly  bear  a  sheet  upon  her.  The 
abdomen  was  puffed  up  and  very  sensitive.  Dr.  Barker 
gave  a  hypodermic  of  fifteen  minims  of  Magendie's  solu- 
tion. After  waiting  half  an  hour,  there  being  no  abate- 
ment in  the  pain,  he  sent  for  an  ether-spray  apparatus,  and 
at  the  same  time  gave  her  another  hypodennic  injection 
of  fifteen  minims.  He  thought  that  there  was  an  in- 
cipient peritonitis,  and  that  the  cold  might  act  favorably 
upon  that  as  well  as  have  a  direct  anaesthetic  action. 
The  patient  meanwhile  had  commenced  vomiting.  He 
then 

SPRAYED  THE  WHOLE  ABDOMINAL  SURFACE 

until  it  was  very  cold,  as  if  it  had  been  covered  with  ice. 
The  relief  was  remarkable;  the  pain  disappeared,  the 
hand  could  be  pressed  firmly  upon  the  abdomen  without 
causing  pain,  and  the  patient  went  to  sleep.  The  pulse 
became  quite  natural  also. 

Next  day  the  menstruation  came  on  again,  and  the 
patient  seemed  very  welL  Dr.  Barker  thought  that  he 
had  very  possibly  aborted  an  attack  of  peritonitis  by  the 
use  of  the  cold. 

This  case  had  naturally  prepared  him  to  expect  much 
from  the  treatment  of  obstetrical  peritonitis  by  cold. 
But  the  question  was  whether,  as  he  had  said,  the  condi- 
tions were  the  same  here  as  in  surgical  peritonitis.  In 
puerperal  peritonitis  we  have  a  natural  and  necessary 
wasting  of  tissue.  This  is  not  the  fact  in  traumatic  peri- 
tonitis. The  prolonged  application  of  cold  has  a  paral- 
yzing and  depressing  effect.  It  reduces  temperature,  but 
does  it  relieve  the  disease  ? 

The  speaker  thought  that  the  use  of  cold  in  puerperal 
peritonitis  was  a  measure  of  doubtful  utility,  especially 
its  prolonged  use.  In  incipient  cases  it  is  extremely 
useful,  but  in  advanced  cases  it  has  a  merely  temporary 
effect. 

Dr.  Barker  was  led  by  a  recent  experience  to  speak 
of  another  point,  viz. : 

THE   SAFETY   OF   HOT  INJECTIONS   IN   ABORTION. 

A  lady  who  had  been  confined  last  spring,  had  made  a 
good  recovery,  and  had  spent  the  summer  at  a  watering- 
place,  came  to  the  city  a  few  days  before  in  order  to 


make  some  purchases  for  a  new  house  which  her  husband, 
a  wealthy  man,  was  building.     She  had  only  menstruated 
once  since  her  confinement,  and  was  at  the  present  time 
eight  weeks  advanced  in  her  second  pregnancy.    She 
had  finished  her  work  and  was  expecting  to  start  on  the 
next  morning  for  Chicago.     In  the  night  (October  2d) 
she  was  taken  with  flooding  and  pain.     Dr.  Katzenbach 
was  called  in  to  see  her.     There  was  not  much  hemor- 
rhage,  but  the    pains   were    severe.      An  examination 
showed  that  there  was  no  protrusion  of  membranes.  To- 
ward morning,  therefore.  Dr.  Katzenbach  began  to  use 
vaginal  injections  of  not  very  hot  water.     He  used  a 
Davidson  syringe  with  a  nozzle  having  only  lateral  open- 
ings.    While  ^ving   the   second  injection,  the  patient 
suddenly  went  into  a  state  of  collapse  and  appeared  as 
if  she  were  going  to  die  at  once.    Stimulants  were  given, 
and  Dr.  Barker  was  summoned.    They  had  been  fighting 
all  day  to  keep  her  alive.    Toward  night  she  had  become 
better  and  seemed  to  be  reacting  from  the  collapse. 

The  patient  was  of  a  fine,  sensitive  temperament ;  and 
the  speaker  believed  that  she  had  suffered  from  nervous 
shock.  There  was  no  evidence  at  all  that  air  had  pa^ed 
into  the  uterus  or  Fallopian  tubes,  and  the  wami  injec- 
tions had  been  given  very  carefully.  During  the  day  the 
membranes  and  foetus  came  away  and  there  was  no  more 
hemorrhage,  nor  had  she  lost  enough  blood  to  account 
for  her  collapse. 

Dr.  Barker  had  never  had  an  experience  like  this  be- 
fore. In  response  to  a  question  he  said  that  he  did  not 
think  that  this  case  showed  that  it  was  dangerous  to  use 
hot  vaginal  injections  in  abortion.  He  admitted  that  the 
relation  between  the  injections  and  the  shock  might  have 
been  one  of  coincidence. 

Dr.  William  M.  Polk  said  that  there  were  three 
points  in  the  therapeutic  use  of  heat  and  cold  of  especial 
interest,  viz.,  the  use  of  cold  in  high  temperatures,  the 
use  of  heat  in  post-partum  hemorrhage,  and  the  use  of 
heat  as  a  vaginal  application  in  cases  of  pelvic  inflam- 
mation. 

With  regard  to  the  use  of 

COLD   IN  HYPERPYREXIA, 

it  was  capable  of  doing  a  great  deal  of  harm.  In  other 
words,  the  mere  fact  of  a  high  temperature  does  not  it- 
self indicate  the  use  of  cold.  Several  years  ago,  while 
visiting  the  general  medical  service  at  Bellevue  Hospital, 
he  had  used  cold  applications  a  great  deal.  Upon  the 
class  of  cases  which  we  come  in  contact  with  in  the  hos- 
pital it  did  not  act  very  well.  It  reduced  the  temperature, 
but  at  the  expense  of  the  vitality  of  the  patient.  He  had 
found,  too,  that  it  was  a  matter  of  great  importance  to 
look  into  the  condition  of  the  kidneys,  because  in  cases 
where  there  is  much  degeneration,  cold  is  liable  to  act 
badly.  Such  a  contingency  is  to  be  looked  for  in  typhoid 
fever  and  post-partum  peritonitis  more  than  after  ovan- 
otomy. 
As  to 

POST-PARTUM   HEMORRHAGE, 

he  was  much  more  disposed  to  rely  upon  the  use  of  heat 
than  of  cold  in  its  treatment.  It  had  seemed  to  him  that 
when  he  had  used  cold  there  had  been  such  an  amount  of 
after-depression  as  to  add  very  much  to  the  danger  of  the 
patient.  He  had  found  hot-water  injections  quite  as 
efficacious  in  checking  post-partum  hemorrhage  as  cold.' 

As  to  the  use  of  hot  injections  in  pelvic  inflammations, 
he  had  found  them  very  valuable.  The  infianiroatory 
exudation  differs,  however,  in  its  absorbability  in  differ- 
ent persons.  There  is  a  class  of  cases  belonging  to 
what  we  used  to  call  the  strumous  diathesis,  and  with 
these  the  exudations  about  the  uterus  are  very  slow  m 
being  absorbed,  while  the  long-continued  use  of  hot  water 
seems  to  retard  rather  than  help.  . 

Dr.  Hunter  said  that  he  entirely  agreed  with  Dr. 
Barker  in  his  opinion  as  to  the  use  of  cold  after  cwxin^ 
ment.  He  did  not  think  that  the  cold  coil  was  so  good 
{n  obstetrical  as  in  surgical  peritonitis. 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


415 


With  regard  to  the  fall  of  the  temperature  and  not  of 
the  pulse,  Dr.  Hunter  said  that  while  this  might  accom- 
pany attempts  to  reduce  fever  rapidly,  he  had  generally 
advised  a  slow  reduction. 

Dr.  Polk  referred  to  a  case  of  scarlet  fever  where  the 

HIGH  TEMPERATURE  WAS  REDUCED  BY  HOT  APPLICATIONS. 

It  was  that  of  a  boy  who  had  been  showing  most  un- 
fevorable  symptoms.  His  temperature  ran  up  to  106°, 
and  there  seemed  little  hope  of  effecting  any  relief.  Dr. 
Metcalfe  advised  that  cloths  be  wrung  out  in  hot  mustard 
and  water  and  placed  about  the  patient  In  half  an 
hour  the  temperature  began  to  fall  and  favorable  symp- 
toms set  in.  It  was  the  only  measure  that  seemed  to  do 
any  good  whatever. 

Dr.  Smffh  referred  to  a  case  in  his  own  experience 
almost  identical,  where  a  child  suffering  from  scarlet  fever 
received  no  benefit  from  cold  applications.  Hot  cloths 
wrong  out  in  mustard-water  produced  a  fall  in  the  tem- 
perature and  the  development  of  favorable  symptoms. 

Dr.  C.  L.  Dana  asked  if  there  were  yet  any  trust- 
worthy statistics  from  American  practice  showing  the 
efficacy  of 

COLD   APPLICATIONS    IN   TYPHOID    FEVER. 

Since  the  beginning  of  his  practice  he  had  been  greatly 
interested  in  this  subject,  having,  while  an  interne  at 
Bellcvue  Hospital,  seen  it  extensively  tried,  and  with 
doubtful  results.  Shortly  after  leaving  Bellevue  he  had 
collected  statistics  of  the  cold-water  treatment  of  typhoid 
fever  in  that  hospital,  and  they  had  not  made  a  favorable 
showing.  The  statistics  quoted  from  Dr.  Peabody  by 
Dr.  Hunter,  as  to  the  results  of  cold  applications  in 
typhoid,  were  of  hospital  cases  and  contained  many 
sources  of  error.  The  statistics  compiled  by  Brand  had 
in  particular  been  shown  to  be  most  fallacious.  The 
speaker  said  that  the  result  of  the  long  debates  on  ty- 
phoid fever  at  the  Acad^mie  de  M^decine  of  Paris  had 
been  unfavorable  to  the  use  of  cold  applications.  In 
England,  too,  the  sentiment  and  evidence  against  it  were 
very  strong.  In  Germany,  recently,  an  opposition  to  the 
once  popular  use  of  cold  was  apparently  developing. 
The  speaker  only  contended  that  experience  had  not  yet 
jnstificd  the  routine  use  of  antipyretics. 

Dr.  Kinnicutt  thought  that  the  statistics  of  the  cold- 
water  treatment  of  t)rphoid  fever  in  this  country  were 
not  sufficiently  large  to  judge  from  them  of*its  efficacy. 
In  Gemiany  the  belief  in  its  efficiency  was  still  fully  main- 
tained, he  thought.  A  careful  study  of  the  last  debate 
on  this  subject  by  London  hospital  physicians  and  the 
statistics  furnished  by  them,  led  to  different  conclusions, 
it  seemed  to  him,  from  those  obtained  by  Dr.  Dana.  In 
France,  the  opinion  of  at  least  the  Lyons  physicians, 
was  all  in  favor  of  the  cold-water  treatment. 


Wound  of  Abdomen— Protrusion  of  Intestine — 
Rapid  Recovery  without  Peritonitis. — The  following 
case,  reported  to  us  by  Dr.  E.  B.  Ward,  of  Greensborough, 
Ala.,  illustrates  the  immunity  against  inflammation  which 
the  peritoneum  sometimes  shows.  In  a  "rough  and 
tumble "  fight  a  man  received  a  wound  in  the  left  in- 
guinal region  just  above  Poupart's  ligament.  After  re- 
ceiving the  wound  he  mounted  a  horse,  rode  one  mile, 
put  up  his  horse,  and  then  walked  another  mile  to  a 
friend's  house.  "  When  I  saw  him,"  writes  Dr.  Ward, 
"he  was  very  much  exhausted.  I  found  the  outer  open- 
ing about  two  inches  in  length,  and  the  inner,  penetrating 
the  abdominal  walls  to  the  cavity,  about  one  inch.  Sev- 
eral folds  of  intestine  with  omentum  protruded,  and  they 
were  only  returned  after  anaesthetizing  the  patient.  I 
first  closed  the  inner  opening  with  interrupted  sutures, 
including  ^^ peritoneum  in  the  sutures.  I  then  closed  the 
outer  integumental  wound  in  the  same  way,  dressing  the 
woand  with  carbolized  dressing,  and  awaited  the  result. 
The  patient  progressed  splendidly  without  a  rise  of  tem- 
perature above  100®,  and  in  less  than  a  week  from  the 
date  of  injury  he  was  up  and  about  his  work." 


THE  NEW  YORK  ACADEMY  OF  MEDICINE. 

Stated  Meetings  October  2,  1884. 

Fordyce  Barker,   M.D.,  LL.D.,  President,  in  the 
Chair. 

Dr.  F.  H.  Bosworth  read  a  paper  (see  page  365)  on 

the  three  tonsils — SOME  PRACTICAL  SUGGESTIOl^S  IN 
REGARD  TO  THEIR  STRUCTURE,  FUNCTION,  AND  DIS- 
EASES. 

The  President  called  upon  several  gentlemen,  not 
specialists  in  diseases  of  the  throat,  to  discuss  the  paper, 
because  of  their  experience  with  certain  points  contained 
in  it.  He  first  said,  with  regard  to  his  use  of  the  bicar- 
bonate of  soda  in  quinsy,  mentioned  by  the  author,  that 
he  had  been  in  the  habit  of  seeing  a  few  cases  of  this  dis- 
ease each  year,  and  until  some  years  ago  they  almost  in- 
variably ended  in  suppuration  ;  but  since  he  had  begun 
the  local  application  of  bicarbonate  of  soda  in  not  a  few 
of  the  cases  the  disease  was  aborted.  A  marked  instance 
of  the  kind  occurred  in  a  patient  seen  with  Dr.  Bosworth, 
a  gentleman  of  eminence  in  literature,  who  was  suffering 
greatly  from  threatening  abscess.  The  next  morning 
after  the  use  of  the  remedy  he  was  found  at  the  breakfast- 
table. 

Dr.  Douglas  would  agree  with  the  author  on  most 
points,  but  there  were  a  few  to  which  he  must  take  ex- 
ception. He  would  agree  with  him,  for  example,  that 
quinsy  was  a  manifestation  of  rheumatism,  or,  especially, 
of  gout,  and  the  treatment  which  he  had  employed  for 
this  affection  was  largely  that  used  by  the  President, 
namely,  bicarbonate  of  soda.  At  the  same  time  he  gave 
the  ordinary  remedies  against  gout.  He  had  found  the 
gargle  and  spray  of  bicarbonate  of  soda  also  useful  in 
cases  of  enlarged  tonsil,  but  one  of  the  most  beneficial 
remedies  for  this  class  of  cases  was  a  powder  composed 
of  one  part  of  menthol  to  a  hundred  parts  of  sugar  of 
milk.  He  would  not  always  resort  to  the  knife  for  the 
removal  of  the  enlarged  tonsil ;  it  could  be  slowly,  but 
surely  reduced  in  size  by  the  persistent  use  of  a  powder 
composed  of  salt,  camphor,  ammonia,  and  sugar  of  milk. 

Dr.  F.  H.  Hamilton  was  inclined  to  agree  with  Dr. 
Bosworth  that  the  enlarged  tonsil  should  be  removed  by 
the  knife ;  yet  he  had  often  observed  that  the  enlarged 
tonsil  of  childhood  disappeared  before  the  twentieth 
year.  He  supposed  the  author,  when  he  said  there  was 
no  danger  connected  with  the  operation,  meant  not  in 
the  acute  or  engorged  stage,  and  not  in  those  of  the 
hemorrhagic  diathesis.  The  question  had  been  raised 
whether  aill  or  only  a  part  of  the  tonsil  should  be  removed  : 
he  should  say  all  that  the  knife  would  include. 

Dr.  Jacobi  believed  that  the  only  efficient  treatment 
for  the  enlarged  tonsil  was  removal ;  applications  would 
not  reduce  its  size,  and  where  they  had  apparently  done 
so  the  reduction  was  due  to  some  other  cause.  The  en- 
larged tonsil  might  remain  stationary  and  appear  smaller 
after  the  lapse  of  years,  because  of  the  growth  of  the 
fauces.  As  to  the  danger  of  hemorrhage,  there  usually 
was  but  little  loss  of  blood,  but  it  might  be  profuse  from 
cutting  into  the  soft  palate — an  accident  which  could 
not  always  be  avoided.  The  most  efficient  means  for 
stopping  hemorrhage  when  it  occurred  was  digital  com- 
pression, applied,  perhaps,  for  an  hour  or  more.  He 
could  not  agree  with  the  author*s  view  that  follicular  ton- 
sillitis was  an  essential  fever ;  he  looked  upon  it  as  a 
local  disease.  What  Dr.  Bosworth  took  to  be  an  essen- 
tial fever  was  probably  diphtheria,  for  cases  of  diphtheria 
were  often  overlooked  or  mistaken  for  some  other  affec- 
tion. It  was  a  great  mistake  to  suppose  that  every  pa- 
tient sick  with  diphtheria  must  necessarily  die ;  there 
were  many  mild  cases  which  went  unrecognized,  and 
which  were  all  the  more  dangerous  for  that  reason,  as 
they  were  the  more  likely  to  spread  the  disease.  Dr. 
Jacobi  laid  particular  stress  upon  this  point  because  of 
its  importance  to  the  public  health. 

Dr.  Weber  had  not  yet  seen  a  case  which  went  to 


4i6 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


substantiate  the  view  that  a  phlegmonous  inflammation 
around  the  tonsils  was  due  to  the  gouty  habit.  He  had 
found  it  most  frequently  in  patients  of  poor  general 
health. 

The  President  remarked  that  guaiacum  had  once 
been  strongly  recommended  in  the  treatment  of  quinsy, 
on  account  of  the  supposed  gouty  origin  of  the  affection ; 
but  he  had  not  obtained  the  results  with  it  which  he  had 
been  led  to  anticipate  from  reading  certain  articles  in  the 
medical  journals. 

Dr.  Post  thought  the  best  treatment  for  the  enlarged 
tonsil  was  extirpation. 

Dr.  Hamilton  had  found  the  external  application  of 
ice  or  snow  the  best  means  for  checking  hemorrhage 
after  removal  of  the  tonsil. 

Dr.  Fruitnight  had  aborted  some  cases  of  quinsy  by 
the  administration  of  the  tincture  of  aconite. 

Dr.  Jarvis  again  called  attention  to  a  distinction 
which  he  had  made  between  the  soft  and  hard,  or  in- 
durated enlarged  tonsil,  the  latter  being  found  in  the 
syphilitic.  If  the  scirrhous  tonsil  were  cut  it  would  surely 
give  rise  to  hemorrhage,  and  might  result  fatally.  He 
employed  the  knife  in  the  removal  of  the  sofl  enlarged 
tonsil,  and  the  cautery  or  snare  in  the  removal  of  the  in- 
durated tonsil.  He  did  not  think  any  more  of  the  tonsil 
should  be  removed  than  was  necessary,  for  it  doubtless 
served  some  physiological  purpose,  as  the  lubricating  of 
the  fauces  and  protecting  the  carotid  artery. 

Dr.  Brandeis  said  he  believed  in  the  Darwinian 
theory  of  the  survival  of  the  fittest :  the  tonsils  had  sur- 
vived some  thousand  years,  had  fulfilled  some  physio- 
logical purpose,  and  he  doubted  not  that  they  performed 
their  function  well,  whatever  it  might  be.  But  the  ton- 
sils, like  other  structures,  were  liable  to  disease,  and 
diseased  tonsils  might  be  worse  than  no  tonsils  at  all, 
and  therefore  he  believed  they  should  in  proper  cases  be 
extirpated.  He  then  pointed  out  the  advantages  of  the 
tonsillilome  over  the  knife  in  certain  cases.  Contrary  to 
the  experience  of  Dr.  Bosworth,  he  had  found  hemorrhage 
in  young  subjects  rather  than  in  the  adult,  although  not 
extreme.  To  prevent  hemorrhage,  he  allowed  the  pa- 
tient to  sip  a  solution  of  tannic  acid,  and  if  necessary,  he 
applied  pressure.  Dr.  Bosworth's  description  of  quinsy 
corresponded  with  that  in  Ziemssen's  *'  Encyclopsedia," 
there  called  peritonsillitis,  but  Dr.  Brandeis  could  not  ac- 
cept the  view  that  it  was  always  an  inflammation  of  the 
peritonsular  sheath.  He  recommended  aconite  and  the 
ammoniated  tincture  of  guaiacum  in  its  treatment  until  an 
abscess  should  have  formed. 

Dr.  Corning  had  arrested  a  severe  hemorrhage  after 
tonsillotomy  in  one  case  by  the  use  of  his  carotid  com- 
pressor. 

Dr.  Bosworth,  in  closing  the  discussion,  said,  with 
regard  to  the  possibility  of  reducing  the  size  of  the  ton- 
sils by  astringents,  that  he  believed  it  could  not  be  donei 
Their  size,  however,  might  be  reduced  in  the  young,  in 
whom  they  were  in  a  state  of  chronic  inflammation,  by 
the  new  tissue  undergoing  contracture.  This  would  ac- 
count for  the  diminished  size  of  the  tonsils  on  reaching 
adult  life.  As  to  hemorrhage  in  the  young,  it  was  only 
an  oozing  ;  considerable  hemorrhage  only  occurred  in 
the  adult.  That  tonsillotomy  was  not  dangerous  was 
apparent  from  the  fact  that  in  all  medical  literature  not 
a  single  fatal  case  was  recorded.  The  cases  in  which 
the  carotid  artery  had  been  wounded  were  excepted ; 
this  accident  could  never  occur  in  the  hands  of  a  surgeon. 
In  arresting  hemorrhage  with  the  actual  cautery,  the  iron 
should  be  applied  from  above  downward,  that  it  might 
not  be  cooled  by  the  flow  of  blood  before  coming  in  con- 
tact with  the  bleeding  vessel.  He  regarded  periton- 
sillitis a  very  good  name  for  quinsy,  but  he  did  not 
believe  there  was  a  peritonsular  capsule  proper.  As  to 
the  tonsils  performing  their  function,  he  did  not  think 
they  existed  in  the  normal  state,  but  that  they  were  the 
result  of  disease. 

The  Academy  then  adjourned. 


®0rr«5V0ttdeti«. 


OUR  LONDON   LETTER. 

(From  our  Special  Correspondent.) 

THE  CHOLERA — DR.  LEWIS  ON  THE  COMMA  BACILLUS  AND 
ITS  NON-SPECIFICITY — CANNIBALISM  AMONG  AN  ING- 
LISH  SHIPWRECKED  CREW — HOSPITAL  SATURDAY— THK 
HEALTH  EXHIBITION  AND  THE  HOSPITALS — DEATH  OP 
MR.  NETTEN  RADCLIFFE. 

London,  September  ao,  1884.*. 

Despite  the  prophets  of  evil,  the  dreaded  cholera  has 
not  yet  visited  us.  All  possible  precautions  have  been 
taken  to  prevent  the  introduction  of  a  case  into  the 
kingdom.  Steps  have  been  taken  to  prevent  cargoes  of 
rags  from  Marseilles  and  other  places  from  being  landed 
at  British  ports  in  cases  where  there  is  any  possibility  of 
their  bringing  infection. 

With  regard  to  the  pathology  of  cholera,  an  interesting 
memorandum  has  just  been  issued  on  the  subject  by  Dr. 
T.  R.  Lewis,  Assistant  Professor  of  Pathology  at  the 
Army  Medical  School,  Netley.  Dr.  Lewis  has  lately 
visited  Marseilles  for  the  purpose  of  studying  the  subject 
practically.  He  criticises  Koch's  published  reports  rather 
closely,  but  the  most  startling  point  in  his  paper  is  the 
statement  that  comma-shaped  bacilli  have  been  found  by 
him  frequently  in  the  salivary  secretions  from  the  mouths 
of  healthy  persons.  This  is  evidently  a  very  importanl 
observation,  and  should  it  be  confirmed  by  further  in- 
vestigations, will  ^o  far  to  wholly  discredit  Koch's  views 
on  the  bacillar  origin  of  cholera.  Dr.  Lewis  is  a  skilled 
microscopist  and  a  laborious  and  patient  worker  in  the 
field  of  pathology.  Dr.  Lewis  has  also  studied  cholera 
practically  in  India,  where  he  served  many  years  as  an 
army  surgeon.  His  former  studies  on  the  filaria  son- 
guinis  hominis  did  much  to  elucidate  the  pathology  of 
those  organisms,  and  are  probably  known  to  many  of 
your  readers. 

While  the  story  of  the  Greely  Arctic  expedition  is  sliD 
fresh  in  our  memories,  another  horrible  tale  of  cannibal- 
ism has  just  come  to  light.  Three  men  and  a  boy  going 
from  England  to  Australia  in  charge  of  a  yacht,  were 
shipwrecked  and  drifted  about  in  an  open  boat  for  nearly 
four  weeks.  As  a  last  resort  they  killed  the  boy,  and 
after  drinking  his  blood  ate  his  flesh.  His  heart  and  liver 
were  devoured  while  still  warm.  It  is  right  to  state  that 
the  boy  was  apparently  dying.  They  continued  to  eat 
his  flesh  for  several  days,  when  they  were  picked  up  by 
a  passing  vessel.  There  is  no  doubt  whatever  as  to  the 
facts,  as  the  men  confess  what  they  have  done,  and  have 
been  arraigned  for  murder.  None  of  the  injurious  eflfects 
alleged  to  occur  from  cannibalism  appear  to  have  fol- 
lowed in  this  case,  as,  despite  their  prolonged  suflferings, 
the  men  seem  now  to  have  recovered  a  large  measure  of 
health.  Much  sympathy  is  expressed  for  them  in  their 
present  position. 

Hospital  Saturday  has  realized  more  than  was  at  first 
thought,  and  the  total  will  be  more  than  last  year.  The 
workshop  contribution  is  still  very  small. 

The  council  of  the  Health  Exhibition  have  handed 
^4,000  to  the  Lord  Mayor  for  distribution  among  the 
London  hospitals. 

Mr.  Netten  Radcliffe  has  just  died  after  a  long  illness. 
He  was  well  known  as  a  sanitary  worker,  and  was  for 
some  time  assistant  medical  officer  to  the  local  govern- 
ment board. 


Menthol  Pencils. — These  pencils  or  cones,  whose 
therapeutic  value  is  very  limited  at  best,  have  become  so 
popular  that  great  adulterations  or  substitutions  are  ikow 
practised.  The  ordinary  oil  of  peppermint  is  probabl/ 
substituted  for  the  menthol,  in  large  part  at  least. 


October  ii,  1884.] 


THE  MEDICAL  RECORD. 


417 


THE  OPHTHALMOLOGIC AL     CONGRESS    IN 
^  HEIDELBERG. 

(From  our  Special  CoRcspondenL) 
MURIATE  OF  COCAINE  AS  A  LOCAL  ANiBSTHETlC  TO  THE 
CORNEA— NO  RADIATING  MUSCULAR  FIBRES  IN  THE 
IRIS— ACTUAL  CAUTERY  IN  SUPERFICIAL  CORNEAL  UL- 
CERATIONS— OPTICO-CILIARY  NEURECTOMY — IS  CATA- 
RACT THE  RESULT  OF  CHRONIC  BRIGHT'S  DISEASE  ? — 
PROFESSOR  ARLT  AND  HIS  RECENT  WORK  IN  GLAU- 
COMA. 

Kbbuzmach,  Gebaiany,  September  19^  1884. 

Sir  :  The  usual  Ophthalmological  Congress  in  Heidelberg 
has  just  closed  its  session,  and  a  few  cursory  notes  at 
this  early  date  may  interest  some  readers.     At  this  meet- 
ing elaborate  papers  are  not  read,  but  condensed  state- 
Dients  are  presented  of  the  subjects  introduced.     The 
notable  feature  of  this  Society  is  that  only  new  things 
or  new  phases  of  old  topics  are  presented.      This  is 
not  from  any  expressed  rule,  but  is  from  the  tacit  under- 
standing which  controls  men  who  are  so  diligently  inves- 
tigating the  unknown  in   science  as  are  these   eager 
workers.    These  men  havie  no  patience  with  mere  reiter- 
ations.   Perhaps  the  most  notable  thing  which  was  pre- 
sented was  the  exhibition  to  the  Congress  upon  one  of 
the  patients  of  the  Heidelberg  Eye  Clinic,  of  the  extra- 
ordinary anaesthetic  power  which  a  two  per  cent,  solution 
of  muriate  of  cocaine  has  upon  the  cornea  and  conjunc- 
tiva when  it  is  dropped  into  the  eye.     Two  drops  of  the 
solution  were  dropped  into  the  eye  of  the  patient  at  the 
first  experiment,  and  after  an  interval  of  ten  minutes  it 
was  evident  that  the  sensitiveness  of  the  surface  was  be- 
bw  the  normal,  then  two  drops  more  were  instilled  and 
after  waiting  ten  minutes  longer  there  was  entire  absence 
of  sensibility,  a  probe  was  pressed  upon  the  cornea  until 
its  surface  was  indented,  it  was  rubbed  lightly  over  the 
sarface  of  the  cornea,  it  was  rubbed  over  the  surface  of 
the  conjunctiva  bulbi,and  of  the  conjunctiva  palpebrarum ; 
a  speculum  was  introduced  to  separate  the  lids  and  they 
were  stretched  apart  to  the  uttermost ;  the  conjunctiva 
bulbi  was  seized  by  fixation  forceps  and  the  globe  moved 
in  various  directions.    In  all  this  handling  the  patient  de- 
dared  (hat  he  felt  no  unpleasant  sensation,  except  that 
the  speculum  stretched  the  lids  so  widely  asunder  as  to 
give  a  little  discomfort  at  the  outer  canthus.     Before  the 
experiment  his  eye  was  shown  to  possess  the  normal 
sensitiveness,  and  the  other  eye,  which  was  not  exi>eri- 
mented  on,  was  in  this  respect  perfectly  normal.     The 
solution  caused  no  irritation  of  any  kind,  nor  did  it  at 
all  influence  the  pupil.     The  anaesthetic  influence  seemed 
to  be  complete  on  the  surface  of  the  eye,  and  it  lasted  for 
about  fift^n  minutes  and  the  parts  then  resumed  their 
usual  condition.     This  first  experiment  was  done  in  the 
presence  of  Professor  Arlt,  of  Professor  Becker,  of  the 
clinical  siaffi  of  Dr.  Ferrer  of  San  Francisco,  of  some 
other  physicians,  and  of  the  writer.     The  next  day  the 
same  experiment  was  performed  on  the  same  patient  in 
the  presence  of  the  Congress  and  with  the  same  results. 
This  application  of  the  muriate  of  cocaine  is  a  discovery 
by  a  very  young  physician,  or  he  is  ])erhaps  not  yet  a 
physician,  but  is  pursuing  his  studies  in  Vienna,  where  he 
also  lives.     His  name  is  Dr.  KoUer,  and  he  gave  to  Dr. 
Brettauer,  of  Trieste,  a  vial  of  the  solution,  to  be  used  in 
the  presence   of  the  Congress  by  Dr.  Brettauer.      Dr. 
K.oller  had  but  very  recently  become  aware  of  this  nota- 
ble effect  of  cocaine,  and  had  made  but  very  few  trials 
with  it.     These  he  had  been  led  to  make  from  his  knowl 
edge  of  the  entirely  similar  effect  which  it  has  for  some 
year  or  more  been  shown  to  have  over  the  sensibility  of 
the  vocal  cords,  and  because  of  which  laryngologists  pen- 
cil it  upon  their  surface  to  facilitate  examinations. 

The  future  which  this  discovery  opens  up  in  ophthalmic 
surgery  and  in  ophthalmic  medication  is  obvious.  The 
momentous  value  of  the  discovery  seems  likely  to  prove 
to  be  in  eye  practice  of  more  significance  than  has  been 
the  discovery  of  anaesthesia  by  chloroform  and  ether  in 
general  surgery  and  medicine,  because  it  will  have  thera- 


peutic uses  as  well  as  surgical  uses.  It  remains,  how- 
ever, to  investigate  all  the  characteristics  of  this  sub- 
stance, and  we  may  yet  find  that  there  is  a  shadow  side 
as  well  as  a  brilliant  side  in  the  discovery.  Professor 
Kiihne,  who  in  the  Heidelberg  Physiological  Laboratory 
worked  out  the  details  of  Boll's  discovery  of  the  visual 
purple  of  the  retina,  received  the  news  of  this  new  dis- 
covery with  the  liveliest  interest  We  may,  i>erhaps,  get 
from  him  a  further  investigation  into  its  properties.  The 
substance  makes  a  clear  solution,  and  is  found  in  Merck's 
catalogue. 

Another  notable  statement  came  from  Dr.  Eversburch, 
of  Munich,  as  the  result  of  very  exact  and  elaborate 
studies,  to  the  effect  that  there  are  no  radiating  muscular 
fibres  in  the  iris ;  in  other  words,  that  the  dUator  iridis 
has  no  existence  in  man.  It  is  found,  he  says,  in  some 
animals,  and  especially  in  those  which  have  oblong  pupils, 
whether  vertical  or  horizontal,  and  in  the  form  of  fasciculi 
at  the  extremities  of  the  slit.  He  absolutely  denies  the 
existence  of  such  fibres  in  the  human  eye,  and  asserts 
that  the  fibres  hitherto  described  under  this  name  are 
nerve-fibres.  These  revolutionary  assertions  were  re- 
ceived with  respect  and  attention,  because  the  investi- 
gator was  known  to  be  a  careful  and  competent  anato- 
mist. If  his  ded:larations  should  be  confirmed,  and  they 
will  not  be  lightly  accepted,  we  must  find  out  a  new 
theory  for  the  active  dilatation  of  the  pupil.  A  good  deal 
of  physiology  will  have  to  be  cast  into  a  new  form.  It 
is  true  that  the  anatomical  discussion  has  not  been  closed 
on  this  point,  but  in  favor  of  the  existence  of  the  dilator 
stand  the  names  of  Merkel,  Henle,  and  Iwanoff  among  re- 
cent investigators.  Eversburch  has  in  his  possession  the 
preparations  of  Iwanoff,  who  died  a  few  years  ago,  and 
he  knows  the  nature  of  the  contest  into  which  he  en- 
ters. 

The  uses  of  the  actual  cautery  in  superficial  forms  of 
corneal  ulceration  and  in  some  other  superficial  pro- 
cesses, especially  in  those  of  micrococcic  origin,  were  dis- 
cussed both  here  and  in  Copenhagen.  There  seems  to 
be  a  general  consensus  as  to  the  usefulness  of  this  treat- 
ment in  selected  cases  of  superficial  corneal  disease,  viz., 
in  ulcus  rodens,  in  superficial  suppurative  processes,  in 
atonic  ulcers,  and  by  Nieden  in  xerophthalmus.  Nieden 
will  shortly  announce  his  views  in  full  in  an  article  in  the 
Archives  for  Ophthalmology,  He  presented  a  most 
delicate  and  elegant  form  of  galvano-cautery  which  he 
had  devised,  and  to  which  he  had  applied  a  very  delicate 
and  promptly  acting  key  invented  by  Professor  Sattler. 
Another  form  of  cautery  is  in  use  in  the  Heidelberg  Eye 
Clinic,  which  has  been  devised  by  Professor  Becker,  and 
is  a  very  small  and  utilizable  Paquelin  cautery.  Both 
these  instruments  can  be  handled  with  nicety  and  deli- 
cacy, and  without  frightening  the  patient,  and  also  in 
most  cases  without  giving  him  any  pain.  This  treatment, 
as  well  as  the  scraping  of  such  ulcers  by  a  sharp  spoon, 
as  does  Meyer,  of  Paris,  is  founded  on  tlie  micrococcic 
theory  of  the  pathology  of  these  processes,  and  marks 
another  forward  step  in  ophthalmic  therapeutics. 

Optico-ciliary  neurectomy  as  a  preventive  of  sympa- 
thetic ophthalmia  has  not  passed  out  of  practice,  as  to  a 
considerable  degree  has  become  the  case  among  us.  So 
able  an  observer  and  logical  a  reasoner  as  Professor 
Schweigger,  of  Berlin,  recommends  its  performance  and 
holds  it  in  higher  esteem  than  enucleation.  He  divides 
the  internal  rectus  muscle  to  gain  easy  approach  to  the 
nerve,  and  he  lifts  it  from  its  bed  by  a  sharp  double 
hook  and  excises  lo  mm.  of  it.  He  is  said  to  be  ex- 
tremely skilful  in  this  proceeding,  and  the  very  small  dis- 
turbance which  he  causes  in  the  structures  of  the  orbit 
may  perhaps  explain  the  success  which  he  has  had  and 
the  confidence  which  he  expresses  in  its  prophylactic 
virtue.  Among  over  a  hundred  cases  which  furnished 
the  material  for  his  conclusions,  in  two  cases  he  saw  occur 
in  the  opposite  eye  an  acute  neuro-retinitis,  with  opalescent 
infiltration,  etc.  There  was  no  reduction  of  vision  either 
central  or  peripheral.      In  two  weeks  the  appearance 


4i8 


THE   MEDICAL  RECORD. 


[October  ii, 


had  entirely  passed  away  without  treatment.  He  regards 
this  inflammation  as  coming  to  pass,  because  neurectomy 
had  beep  attended  by  unusual  effusion  of  blood  into  the 
sheath  of  the  divided  nerve — that  this  had  obstructed  the 
lymph  channels,  and  a  process  had  thus  been  set  up 
which  travelled  around  by  the  chiasma  to  the  opposite 
eye,  and  there  expressed  itself  in  a  lymphatic  neuro- 
retinitis  such  as  is  well  known  to  occur.  The  explanation 
is  very  plausible.  Another  most  peculiar  observation 
among  his  cases  was,  that  in  one  of  them  the  anterior 
part  of  the  eye  was  normal,  and  when  the  nerve  was 
excised  the  pupil  at  once  expanded  to  an  extreme 
degree,  more  widely  than  it  is  possible  for  atropine  to 
produce.  He  put  eserine  into  the  eye  and  found  that 
by  it  the  pupil  at  once  became  contracted,  as  is  usual 
with  this  drug.  To  this  Professor  Laqueur  justly  re- 
marked that  absolute  proof  was  thus  afforded  that,  as  has 
been  before  claimed,  the  action  of  eserine  is  not  upon 
the  nerves  of  the  iris,  but  is  directly  upon  the  muscular 
fibres.  A  beautiful  experiment  in  physiology  was  thus 
made  with  conclusive  result. 

A  most  laborious  statistical  paper  was  presented  by 
Professor  Becker  to  elucidate  the  question  whether  it  is 
true,  as  has  lately  been  averred  by  Deutschmann,  that 
cataract  is  the  result  in  many  cases  of  chronic  Brighf  s 
disease.  To  arrive  at  a  trustworthy  conclusion,  Professor 
Becker  summed  up  the  results  of  a  most  exhaustive  and 
exacting  series  of  studies,  first  of  patients  with  cataract, 
whether  they  liad  albuminuria;  then  of  persons  within 
the  limits  of  age  when  both  cataract  and  albuminuria 
chronica  may  occur,  who  were  not  aware  of  an^  trouble 
of  sight  or  of  the  kidneys,  as  to  whether  they  might  have 
incipient  cataract  with  or  without  kidney  trouble,  and 
these  persons  he  found  in  insane  asylums,  in  poor-houses, 
in  retreats,  and  among  the  patients  in  his  clinic  and  else- 
where ;  thirdly,  he  went  through  the  records  of  250,000 
autopsies  which  had  been  made  in  Vienna  of  cases  of 
Bright' s  disease,  to  see  how  often  cataract  had  been  noted 
to  exist.  The  hnal  sum  of  this  vast  amount  of  labor  was 
treated  according  to  the  principles  of  the  mathematics 
of  the  doctrine  of  probabilities,  and  the  outcome  of  it  all 
was  found  in  the  conclusion  that  Deutschmann  was  not 
justified  in  his  assertions,  and  that  cataract  cannot  with 
reasonable  and  just  probability  be  declared  to  be  an  ef- 
fect of,  although  it  may  occur  with,  degeneration  of  the 
kidneys. 

It  was  a  delightful  feature  of  this  meeting,  the  presence 
of  the  simple-minded  and  clear- thinking  Professor  Arlt, 
who,  because  he  had  passed  the  statutory  line  of  seventy 
^ears,  had  been  retired  from  the  chair  of  ophthalmology 
in  Vienna  two  years  ago.  The  loving  and  pious  respect 
in  which  he  was  held  was  delightful  to  observe.  He  rose 
to  his  feet  several  times  when  clinical  themes  were  being 
discussed,  and  the  range  of  his  memory  of  facts  and 
cases,  and  his  clear  utterances,  showed  that  the  edge  of  his 
intellect  had  not  been  blunted.  As  a  proof  of  his  mental 
activity,  he  brought  with  him  a  treatise  on  **  Glaucoma," 
which  had  just  come  through  the  press  and  in  which,  in 
[42  pages,  he  sets  forth  with  characteristic  clearness  and 
acumen,  and  with  great  wealth  of  knowledge  both  of 
books  and  of  cases,  his  views  on  this  disputed  theme. 
Certain  I  am,  from  what  I  have  read  of  it,  and  from  con- 
fidential and  candid  conversation  with  him,  that  we  shall 
owe  to  him  much  valuable  instruction  on  this  subject. 
His  views  are  sure  to  make  a  deep  impression  and  to 
gain  wide  acceptance.  I  hope  the  book  may  be  elabo- 
rately reviewed  in  some  American  journal,  so  as  to  get 
the  marrow  of  it  in  English. 

It  were  hardly  modest  to  speak  of  the  kindly  way  in 
which  American  visitors  are  treated  in  these  meetings ;  a 
man  afflicted  with  less  than  the  average  modicum,  of  van- 
ity runs  great  risk  of  an  acute  exacerbation  of  his  frailty, 
while  the  average  man  with  average  self-esteem  simply 
loses  his  head. 

With  much  regard,  very  sincerely, 

Henry  D.  Noves,  M.D. 


A  SUGGESTION  TO  ESTABLISH  FREE  BATHS 
AND  WASHING-HOUSES  FOR  USE  DURING 
THE  YEAR. 

To  THE  Editor  op  The  Medical  Rccoro. 

Sir  :  In  my  reports  to  the  New  York  Board  of  Health,  dur- 
ing  the  years  1868, 1869,  and  1870,  when  I  made  a  survey 
of  the  Twentieth  Sanitary  Inspection  District,  in  my  ca- 
pacity  of  Assistant  Sanitary  Inspector,  I  already  advo. 
cated  the  establishment  of  free  baths  as  a  sanitary  measuie 
for  the  improvement  of  the  condition  of  the  poor.  Since 
then  free  baths  have  been  supplied  by  the  authorities  in 
this  city  during  the  summer  months,  but  no  provision  has 
been  made  for  this  luxury  during  eight  months  of  the 
year,  viz.  :  from.October  ist,  to  about  June  ist.  To  sup- 
ply  this  deficiency,  I  have  recently  again  laid  this  mat- 
ter before  the  Board  of  Health  and  the  Mayor  of  this 
city,  who  kindly  approved  and  indorsed  my  views  re- 
garding the  establishment  of  free  baths  and  washing- 
houses,  and  promised  to  co-operate  with  me  to  carry  out 
my  suggestions,  as  far  as  lay  in  their  power. 

Regarding  the  usefulness  of  such  institutions,  for  ob- 
vious reasons,  hardly  anything  needs  to  be  said.  But, 
being  a  measure  of  general  utility,  as  a  preventive 
against  so-called  zymotic  diseases — which  I  would  term 
filth-diseases — I  herewith  make  some  suggestions  as  to 
how  the  means  could  be  supplied  wherewith  to  provide 
these  establishments. 

T.  Part  of  the  excise  moneys  could  be  used  for  this 
purpose,  besides  private  contributions,  if  the  attention  of 
the  public  were  called  to  the  necessity  of  such  buildings, 
wherein  the  poor  could  bathe  and  wash  their  linen  free 
of  charge.  I  am  already  assured  by  Mayor  Edson,  as 
stated  above,  that  as  the  head  of  the  Board  of  Apportion- 
ment  and  of  all  the  city  departments  he  would  use  his 
influence  for  securing  from  the  city  the  necessary  build- 
ing lots,  whereupon  these  proposed  establishments  could 
be  erected. 

2.  The  Legislature  should  pass  a  law — ^additional  10 
the  Tenement-House  Law — whereby  every  owner  of  a 
house  should  be  taxed,  say,  one  dollar  annually,  addi* 
tional  to  the  present  taxes,  for  every  tenant  occupying 
his  house. 

3.  I  would  suggest  that  every  emigrant  coming  to  this 
country  should  be  advised,  if  deemed  necessary  by  the 
examining  physician  at  the  place  of  landing,  to  make  use 
of  these  cleansing  establishments  on  entering  the  terri- 
tory of  the  United  States. 

4.  Every  prison  and  police  station  and  other  public 
institution  should  have  a  bath  attached  for  the  use  of 
the  inmates. 

5.  The  lower  classes,  employed  by  the  city,  county, 
or  State,  should  be  requested  by  their  superiors  to  avail 
themselves  of  the  use  of  the  free  baths  and  washing- 
houses.  Proprietors  of  large  establishments,  factories, 
stores,  stables,  etc.,  would  follow  the  example  of  the  au- 
thorities by  employing  by  preference,  all  other  conditions 
being  equal,  clean  and,  therefore,  healthier  people.  Con- 
sequently a  moral  pressure  could  be  exercised  over  ser- 
vants and  employes  generally  for  their  own  good. 

6.  While  I  was  stationed  on  the  fi-ontier,  and  at  other 
military  posts,  as  Post  Surgeon  in  the  United  States  Army, 
I  have  often  regretted  the  absence  of  baths,  for  the  use  of 
the  soldiers,  connected  with  their  barracks  or  quarters. 
The  United  States  Government  would  no  doubt  greatly 
ameliorate  the  sanitary  condition  of  our  soldiers  and 
sailors  by  erecting  free  baths  for  them  wherever  prac- 
ticable. 

If  means  were  provided  by  the  public  authorities  or 
philanthropists  for  facilitating  the  constant  washing  and 
cleansing  of  persons  and  dwellings,  I  think  we  would 
have  less  of  cholera,  yellow  fever,  and  other  epidemics  of 
filth- diseases,  and  the  germs  of  many  diseases  would  be, 
in  part  at  least  if  not  effectually,  eradicated. 

In  closing  these  remarks  and  suggestions,  written  for 
the  consideration  and  with  a  view  of  enlisting  the  co- 


October  n,  1884.] 


THE  MEDICAL  RECORD. 


419 


operation  of  some  of  the  readers  of  The  Record,  and 
m  bono  publico^  I  will  only  add  that  the  plan  of  estab- 
Usbiog  cheap,  though  not  free,  baths  and  washing-houses 
has  been  tried  in  London,  £ng.,  within  the  past  four  or 
five  years  I  believe.  These  are  situated  in  the  following 
parishes :  (i)  Paddington,  (2)  Marylebone,  (3)  St.  Pan- 
eras,  (4)  St.  Giles,  (5)  Lambeth,  etc.  The  general  ar- 
raogemenl  there  is  :  A  private  bath  costs  twopence 
(about  four  cents)  a  head,  including  towels ;  a  higher- 
class  bath,  twelve  cents  ;  swimming  bath,  the  same  price  ; 
privilege  of  use  of  large  room  for  washing,  drying,  iron- 
ing, etc.,  at  nominal  rates.  The  baths  are  generally 
self-sapporting  and  very  extensive.  Some  houses  have 
several  swimming  baths,  each  swimmer  having  a  separate 
hox  to  dress  in,  etc.  Rupolph  Tauszky,  M.D. 

6<0  LSXIMGTON  AVBNUB,  NbW  YoRK. 


NO  MEDICAL  HISTORIES  OBTAINABLE  FROM 
ST.  LUKE'S   HOSPITAL,  NEW  YORK. 

To  THK  Editor  op  Thb  Medical  Record. 

Sir  :  Will  you  be  so  kind  as  to  publish  the  enclosed 
correspondence,  which  speaks  for  itself. 

1  was  called  to  see  a  gentleman  under  the  circum- 
stances as  stated  in  my  letter,  and  believing  that  some 
inforaiation  in  regard  to  his  former  sickness  would  ma- 
terially aid  me  in  his  case,  I  addressed  a  communication 
to  Rev.  George  S.  Baker,  making  inquiries  to  that  end. 
The  enclosed  letters  are  the  one  I  received  from  him 
and  my  answer.  I  think  it  should  be  known,  to  the  medi- 
cal community  at  least,  that  no  physician  can  gain  any 
information  in  relation  to  a  party  who  has  been  a  patient 
in  St.  Luke's  Hospital. 

Jos.  P.  FESSENDENy  M.D., 

Member  Medical  Staffs  Salem  Hospital. 

Salxm,  Mass.,  October  4^  1884. 

P.S. — I  thought  it  best  upon  the  whole  to  ask  you  to 
give  place  to  the  correspondence,  instead  of  the  public 

journals. 


St.  Luke's  Hospital,  New  Yokk,  September  ao,  2884. 

Dr.  J.  P.  Fessenden,  Salem,  Mass. : 

Dear  Sir  :  It  is  positively  against  the  rules  of  tliis  hos- 
pital to  communicate  what  we  learn  with  regard  to  the 
diseases  of  our  patients  to  any  one,  save  to  the  patients 
themselves,  if  they  request  it,  or  to  the  District  Attorney, 
if  he  demands  it  for  purposes  of  justice.  We  shall  not 
deviate  from  this  nile  in  the  case  of  Mr.  B .  Prob- 
ably you  are  not  aware  that  your  own  is  the  third  letter 
which  has  been  written  me  on  the  same  subject. 

Yours  truly,  Geo.  S.  Baker, 

Pastor  and  Superintendent, 

Dear  Sir  :  I  was  exceedingly  surprised  to  learn  from 
your  communication,  received  this  morning,  that  no  in- 
formation relating  to  ihe  sickness  of  a  patient  who  had 
been  in  your  hospital  could  be  imparted  to  the  attending 
physician  of  the  patient  after  he  left  your  hands.  We 
have  an  idea  in  this  vicinity  that  we  have  some  pretty 
good  hospitals,  such  as  the 
Massachusetts  General  and 
Boston  City,  both  of  which 
are  ready  to  extend  such 
courtesies  to  the  family  physician  and  both  of  which 
would  receive  the  condemnation  of  the  public  if  they  re- 
fused so  to  do.  The  patient,  after  an  absence  of  six 
jears,  without  any  knowledge  of  him  coming  to  his  sister 
during  that  time,  suddenly  appeared  at  her  home  (she  is 
a  widow  and  in  straitened  circumstances),  penniless, 
poorly  clothed,  much  emaciated,  and  mentally  unsound. 
I  was  called  to  see  him  and  had  and  now  have  no  doubt 
bat  that  some  information  in  regard  to  his  sickness  in  St. 
Luke's  Hospital  would  aid  me  in  the  treatment  of  the 
case.  You  are  probably  aware  that  any  information  con- 
veyed by  patient,  family,  or  friends,  is  held  sacred  by  the 
attending  physician,  and  you  refuse  positively  to  com- 


municate such  information  for  the  benefit  of  the  patient 
whose  welfare  is  entrusted  to  me.  It  seems  to  me  to  be 
an  unheard-of  procedure.  I  do  not  know  that  the  fact 
that  you  have  been  written  to,  asking  for  information 
three  times,  concerns  me  in  the  least,  even  did  I  know  it, 
which  I  do  not. 

If  I  can  elicit  ho  facts  from  you,  I  shall  publish  your 
letter  in  the  New  York  papers,  with  an  explanation  in 
regard  to  it.     I  think  the  public  should  be  made  ac- 
quainted with  such  a  rule  of  the  hospital  for  its  guidance. 
Very  respectfully  yours, 

J.  P.  Fessenden,  M.D., 
Member  Medical  Staffs  Salem  Hospital. 

Salem,  Mass.,  September,  1884. 

[It  is  difficult  to  understand  upon  what  grounds  any 
public  hospital  can  refuse  to  give  to  a  medical  gentleman 
in  charge  of  a  patient  such  information  as  was  solicited  by 
our  correspondent.  We  should  like  to  have  some  explana- 
tion on  this  point  from  the  hospital  authorities. — Ed.] 


^ew  Ittstrumetxts* 


A  NEW    NEEDLE    FOR  CONTINUOUS    OR   IN- 
TERRUPTED SUTURE. 

By  G.  WACKERHAGEN,  M.D., 

BROOKLYN,  N.  Y.] 

The  under  surface  of  this  needle  is  grooved  to  within 
three-eighths  of  an  inch  from  the  point,  when  the  channel 
is  crossed  by  a  narrow  depressed  bridge ;  under  this  the 
thread  is  passed,  and  returning  over  the  bridge  again  falls 
into  the  groove  of  the  needle,  thereby  preventing  ob- 
struction to  its  passage  through  the  tissues.     There  is 


%:iX»KNMi  liC^. 


also  an  eye  near  the  blunt  end  so  that  it  may  be  used  for 
continuous  suture. 

The  special  advantage  claimed  for  this  needle  is  that 
it  is  not  necessary  to  remove  *the  needle-holder  while 
operating  by  interrupted  suture.  The  needle  having 
passed  through  the  flaps,  the  thread  is  caught  by  dressing- 
forceps  and  the  needle  withdrawn. 


A  NEW  BULLET  FORCEPS. 
By  WILLIAM  R.  LEONARD,  M.D., 

NEW  YORK. 

The  accompanying  cut  represents  a  new  and  improved 
bullet  forceps.  For  the  last  twenty  years  nothing  has 
been  done  to  improve  the  method  of  extracting  bullets.  All 


instruments  in  use  for  this  purpose  up  to  the  present 
time  are  deficient  in  many  respects,  and  are  apt  to  slip 
after  they  have  engaged  the  bullet.  The  instrument  here 
presented  consists  of  a  steel  cylinder  inclosing  a  steel  sty- 
let riveted  to  two  jaws,  which  are  hinged  and  terminate 
in  short  steel  teeth,  which  take  a  firm  hold  upon  any  part 
of  the  bullet  by  burying  themselves  in  its  substance. 
The  instrument  is  introduced  closed.  When  the  bullet 
is  reached  the  jaws  are  opened  by  turning  the  screw  at 
the  proximal  end,  and  the  instrument  is  then  pushed  up 
so  that  the  jaws  grasp  the  bullet ;  a  few  tiums  of  the  screw 
bury  the  teeth  in  the  bullet  firmly  and  make  it  part  and 
parcel  of  the  instrument. 


420 


THE  MEDICAL  RECORD. 


[October  ii,  1884. 


Official  List  of  Changfs  in  the  Stations  and  Duties  cf  Officers 
serving  in  the  Medical  Department ^  United  Slates  Army^ 

from  September  28  to  October  4,  1884. 

Bentley,  Edwin,  Major  and  Surgeon.  Granted  two 
months*  leave  of  absence,  with  permission  to  apply  for 
two  months'  extension — to  take  eflfect  upon  assignment 
to  duty  in  the  Department  of  Texas  of  .Surgeon  F.  L. 
Town.  S.  O.  121,  Headquarters  Division  of  the  Mis- 
souri, September  30,  1884, 

Bartholf,  John  H.,  Captain  and  Assistant  Surgeon. 
Assigned  to  duty  at  Fort  Ringgold,  Texas,  as  Post  Sur- 
geon. S.  O.  129,  par.  5,  Headquarters  Department  of 
Texas,  September  25,  1884. 

Crampton,  L.  W.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month  and  ten  days. 
S.  O.  60,  Headquarters  Division  of  the  Atlantic,  Oc- 
tober 2,  1884. 

Gibson,  R.  J.,  First  Lieutenant  and  Assistant  Surgeon. 
Assigned  to  duty  as  Post  Surgeon,  Fort  Winfield  Scott, 
California,  relieving  Assistant  Surgeon  A.  S.  Polhemus. 
S.  O.  115,  par.  I,  Headquarters  Department  of  Cali- 
fornia, September  23,  1884. 

Polhemus,  A.  S.,  First  I^ieutenant  and  Assistant  Sur- 
geon. Upon  being  relieved,  to  report  to  commanding 
officer  Fort  McDermit,  Nevada,  for  duty  as  Post  Sur- 
geon. S.  O.  1 1 5,  par.  i.  Headquarters  Department  of 
California,  September  23,  1884. 

White,  R.  H.,  Captain  and  Assistant  Surgeon.  To 
report  to  commanding  officer  Angel  Island,  California, 
as  Post  Surgeon,  relieving  Assistant  Surgeon  C.  K.  Winne. 
S.  O.  115,  par.  I,  Headquarters  Department  of  Cali- 
fornia, September  23,  1884. 

Winne,  C.  K.,  Captain  and  Assistant  Surgeon.  Upon 
being  relieved,  to  report  to  commanding  officer  Benicia 
Barracks,  California,  for  duty  as  Post  Surgeon,  relieving 
Surgeon  C.  C.  Byrne.  S.  O.  115,  par.  i.  Headquarters 
Department  of  California,  September  23,  1884. 

Everts,  Edward,  First  Lieutenant  and  Assistant  Sur- 
geon. Granted  leave  of  absence  for  one  month,  with 
permission  to  leave  the  limits  of  the  Department.  S.  O. 
145,  Headquarters  Department  of  Colorado,  Septem- 
ber 24,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  October  4,  1884* 

Stewart,  Henry,  Surgeon.  Granted  leave  of  absence 
for  one  year,  with  permission  to  leave  the  United  States. 
October  15,  1884. 

Edgar,  John  M.,  Passed  Assistant  Surgeon.  De- 
tached from  the  Nantucket  and  placed  on  waiting  orders. 
September  29,  1884. 

Harmon,  G.  E.  H,,  Passed  Assistant  Surgeon.  To 
the  Ifaval  Academy.     September  30,  1884. 

Bertolette,  D.  N.,  Passed  Assistant  Surgeon.  From 
the  Naval  Academy  to  the  Dolphin.     October  4,  1884. 

Rogers,  Benjamin  F.,  Passed  Assistant  Surgeon.  To 
the  Naval  Academy.     September  30,  1884. 

CooKE,  George  H.,  Surgeon.  From  the  Naval 
Academy,  and  placed  on  waiting  orders.  October  2, 
1884. 

Whiting,  Robert,  Passed  Assistant  Surgeon.  From 
the  Naval  Academy  and  placed  on  waiting  orders.  Octo- 
ber 4,  1884. 


Breakfast. — In  the  time  of  Henry  VIII.,  the  Queen's 
Maids  of  Honor  had  each  a  chet  loaf,  a  manchet,  a 
gallon  of  ale,  and  a  chine  of  beef  for  their  breakfasts. 
What  did  they  have  for  dinner  ? 


^edicaX  |tmuB. 


C0MTA010U8  Diseases — Weekly  STATBMENT.->Re- 
port  of  cases  and  deaths  from  contagions  diseaies  re. 
ported  to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  October  4,  1884 : 


Week  Ending 


Cas4s, 

September  27, 1884. 
October  4,  1884 


Deaths, 

September  27,  1884. 
October  4,  1884 


13  I  3 
13     o 


I 


O      0 
O      0 


LovAGE. — The  levisticum  of  botany  has,  on  Dr.  John- 
son's authority,  a  virtue  in  the  relief  of  rheumatism.  He 
says:  ''Take  equal  quantites  of  flour  of  sulphur  and 
flour  of  mustard  seed,  make  them  into  an  electuary  with 
honey  or  treacle,  and  take  a  bolus  as  big  as  a  nutmeg 
several  times  a  day,  drinking  after  it  a  quarter  of  a  pint 
of  the  infusion  of  the  root  of  lovage.  The  relief  is  speedy 
and  lasting."  But  perhaps  sulphur  will  answer  alone. 
Lovage,  like  sassafras,  belongs  to  a  large  class  of  plants 
contaming  an  essential  oil,  which  have  always  been  em- 
ployed as  carminatives,  diuretics,  emmenagogues,  and 
digestive  stimulants,  in  flatulent  dyspepsia,  amenorrhoea, 
dropsy,  and  rheumatism. 

For  Hvperhidrosis  of  the  Feet  Dr.  Duhring  has 
used  the  following  with  good  results  : 

15.    Zinci  oleati 3  ij. 

Amyli, 

Talci aa  3  Hj. 

M.  Sig. — Dusting  powder. 
This  was  applied  to  the  feet  after  they  had  been  washed 
with  a  lotion  of  tincture  of  belladonna. 

Thincs  to  Try. — Dr.  Robert  A.  Reid,  of  Boston,  in 
his  Eclectic  Journal^  suggests  the  following  "  things  to 
try'*  when  ordinary  measures  fail:  Try  pop-corn  for 
nausea  and  vomiting  of  pregnancy ;  try  sun-bath  for 
rheumatism;  try  cranberry  poultice  for  erysipelas;  try 
lager  beer  as  a  gargle  for  sore  throat ;  try  eating  fresh 
radishes  and  yellow  turnips  for  gravel ;  ti^  eating  onions 
and  horse-radish  to  relieve  dropsical  sweUmgs  ;  try  taking 
cod-liver  oil  in  tomato  cat.sup  if  you  want  to  make  it 
palatable  ;  try  snuffing  powdered  borax  up  the  nose  for 
"  cold  in  the  head  ;**  try  hard  cider— one  glassful  three 
times  a  day — ^for  ague  or  rheumatism  ;  try  breathing  the 
fumes  of  turpentine  or  carbolic  acid  to  relieve  whooping 
cough  ;  try  a  cloth  wrung  out  of  'cold  water  put  about 
the  neck  at  night,  for  sore  throat ;  try  planting  sun- 
flowers in  your  garden  if  you  live  in  a  malarial  region 
and  the  travelling  is  bad. 

A  Case  of  Rose  Cold. — Dr.  F.  B  Streeter  sends  a 
history  of  a  case  of  "rose  cold,"  as  suggested  by  Dr. 

Mackenzie  :  "  Mrs.  William  B ,  aged  thirty-five  years, 

native  of  this  State,  of  Dutch  descent,  married,  and  bar- 
ren. With  the  exception  of  an  uterine  disease,  which  is 
the  probable  cause  of  her  sterility,  she  is  in  a  fair  state 
of  health.  I  first  saw  her  some  three  years  since.  She 
was  suffering  from  an  intense  coryza,  and  attributed  it 
to  the  fact  that  while  walking  in  the  dark  she  had  acci- 
dentally brushed  against  a  bush  laden  with  full-blown 
roses.  She  explained  that  she  had  been  aflected  thus 
by  roses  since  her  childhood,  and  as  she  is  a  lady  oi  in- 
telligence her  case  seems  to  be  clearly  one  of  ^  rose  cold' 
She  has  no  catarrh  or  any  other  disease  of  the  respir- 
atory system,  nor  is  she  similarly  affected  by  the  pollen 
of  any  other  flower  or  plant." 


The   Medical   Rec 


A   Weekly  yournal  of  Medicine  and  Surgery 


C#iCAL  [% 


rrr.- 


CITY  IIO^'^ 


Vol.  a6,  No.  x6 


New  York,  October  i8,  1884 


Whole  No.  798 


^trigiimX  li^rttcleB. 


CONTRIBUTIONS  TO 
THE  ANATOMY   OF  THE  LEMNISCUS. 

^ITH  RkM ARKS   ON  CeNTRIPKTAL  CONDUCTING  TRACTS 

IN  THE  Brain. 
By  E.  C.  SPITZKA.  M.D., 
nranasoK  op  nkuko-anatomy  and  physiology  in  ths  new  york  post-cxad- 

UATB  UBDICAL  ilCHOOL. 

(Continued  from  page  3S^>) 
II. 

III. — ^The    Component   of    the    Lemniscus    which 

PASSES   THROUGH  THE   InTEROLIVARY  LAYER. 

In  the  sequel  it  is  my  intention  to  discuss  only  a  por- 
tion of  the  axial  fibre-systems  which  have  been  by  vari- 
ous authors  '  designated  as  lemniscus,  under  that  name, 
leaving  the  critique  of  this  designation  to  the  concluding 
remarks.  In  the  lower  (caudal)  part  of  the  oblongata 
these  tracts  are  found  in  such  relations  as  to  enable  us 
most  readily  to  understand  their  connections  with  the 
important  spinal  tracts,  and  the  older  authorities  and 
some  of  the  more  recent  ones  include  the  olivary  fascicu- 
lus, which  is  larger  than  the  mterolivary  layer. 

A  section  made  at  the  level  indicated  in  the  accom^ 
panying    figure  reveals  the  following  prominent  gray 


stance  surrounding  the  central  canal,  in  whose  distal  por- 
tions the  hypoglossal  and  vagus  (yago-accessorius?)  nuclei 
begin  to  appear ;  fourth,  the  reticular  gray  substance  in 


»C 


Fig.  3. 

(ganglionic)  substances  :  First,  the  nuclei  of  the  columns 
of  Burdach  and  Goll ;  second,  the  ganglionic  substance  of 
the  column  of  Rolando ;  •  third,  the  gelatinous  gray  sub- 

*5»«IJt  liie  one  in  which  the  term  is  employed  by  Meynert  in  hi»  last  work, 
rsychiame,  Part  I.,  which  is  over-amok,  and  evidently  intended  to  just^  cer- 
**?•?[•      older  and  untenable  views,  whidi  he  seems  disinclined  to  abandon. 

"This  contains  three  categories  of  ganglionic  substance,  viz.,  the  convoluted 
amnia  corresponding  to  the  gelatinous  head  of  the  posterior  horn  of  the  spinal 
Sny,  the  subjacent  paler  staining  spongy  gray  substance,  and  the  intercabted 
py  istaads  m  the  root  itseli;  conuinmg  cells  like  those  of  the  nuclei  of  Goll  and 
Bwdacfa.  The  absence  of  the  gelatinous  head  in  reptiles  would  seem  to  indicate 
a  rdaoon  to  one  of  the  specialized  forms  of  sensation,  whether  of  conuct  or  tem- 
perature, more  likely  the  latter. 


Fig  4- 

the  field  intermediate  to  the  bridge  of  gray  matter  (which 
unites  those  nuclei  which,  for  brevity's  sake,  I  shall  term 
the  nuclei  of  Goll,  Burdach,  and  Rolando^,  the  central 
gelatinous  substance,  ana  the  lemnis- 
cus ;  fifth,  the  olivary  nucleus,  which  in 
this  level  is  represented  only  by  that 
portion  which  is  known  as  the  inter- 
nal accessory  olive  {p) ;  sixth,  the  small 
nuclei  interpolated  in  the  external  ar- 
ciform  fibres  (na\  Of  these  various 
gray  substances  the  nuclei  of  Burdach 
and  Goll  and  the  olive  have  relations 
Ikttf  to  the  lemniscus,  thus  indicating  what 
an  extensive  territory  this  fibre  agglom- 
eration occupies. 

Surrounding  on  its  medial  and  dorsal 
confines  the  nucleus  of  Goll,  and  cap- 
ping dorsad  the  nucleus  of  Burdach, 
are  the  fibre-tracts  of  the  columns  of 
the  same  name.  As  we  proceed  ceph- 
alad  we  find  that  the  mass  of  these  col- 
umns undergoes  a  gradual  reduction. 
In  the  main  this  reduction  appears  to 
be  effected  by  the  entry  of  the  fibres 
into  the  nuclei.  These  are  fielded  off 
by  intersecting  delicate  fasciculi  into  nu- 
merous subnuclei.  The  nearer  the  spi- 
nal cord,  the  more  compact  (and  smsdl) 
is  the  nucleus  of  Goll  {nucleus  funiculus 
gracilis) ;  the  nearer  the  middle  of  the 
middle  olivary  altitude,  the  more  scat- 
tered and  subdivided  are  its  cell-groups, 
and  the  more  distinctly  does  it  appear  as  if  the  whole 
mass  of  the  column  of  Goll  broke  through  the  nucleus  to 
separate  into  the  strands  of  the  internal  arciform  fibres 
(Fig.  4).  Much  as  the  anatomical  appearances  suggest 
the  existence  of  a  direct  connection  between  the  column 
of  Goll  and  the  internal  arcuate  fibres  mentioned,  a 
study  of  the  phenomena  of  secondary  degeneration  does 
not  sustain  the  existence  of  such  a  connection  as  a 
direct  one. 

In  the  case  of  secondary  degeneration  to  which  I  have 


422 


THE  MEDICAL  RECORD. 


[October  i8,  1884. 


aUndedf  I  found  ^'that  'the  fasciculi  interpolated  in  the 
nuclei  of  GoU  and  Burdach  showed  a  reduction  in  size 
on  the  side  opposite  to  the  degenerated  lemniscus  field. 
The  third  and  fourth  figures  accompanying  this  paper  il- 
lustrate this  relation.  In  Fig.  3,  the  dark  field  Da^  Z>x*, 
Z>y  which  represents  the  descending  defeneration,  con- 
nects by  diagonal  raphe  strands  {Dr)  with  degenerated 
arciform  bundles  {Darc)^  which  pass  into  the  degener- 
ated fields  Zyi,  Zyi*,  and  -Q/j,  and  these  in  turn  con- 
nect with  the  degenerated  intemuclear  fasciculi  in  the 
nuclei  of  GoU  and  Burdach. 

The  part  of  the  lemniscus  degenerated  in  the  above 
case  corresponds  to  Flechsig's  interolivary  stratum.* 
In  a  section  of  the  level,  shown  in  Fig.  4,  this  stratum  is 
L-shaped  (the  dark  area  D,  Dsy  Da\  consisting  of  a 
vertical  field  (Z>)  which  fills  up  the  interval  between  the 
raphe  (r),  the  internal  accessory  olive,  and  the  pyramid 
tract,  and  a  nearly  horizontal  field  {Ds)  which  lies  be- 
tween the  halo  of  the  denticulate  (main)  olivary  nucleus 
and  the  pyramid ;  it  extends  with  an  angular  swelling  to 
the  point  of  emergence  of  the  hypoglossal  nerve-roots 
Da  (see  corresponding  designations  of  Fig.  3).  Inas- 
much as  the  degeneration  can  not  be  traced  into  the 
tracts  included  in  Burdach's  and  GoU's  columns,  but  only 
4nto  the  nuclei  of  these  columns,  it  is  to  be  inferred  that 
the  latter  are  interpolated  between  two  divisions  of  one 
and  the  same  tract.  In  other  words,  that  the  spinal  col- 
umns of  GoU  and  Burdach  terminate,  anatomically 
speaking,  in  their  nuclei,  and  that  from  these  '*  inter- 
rupting "  nuclei  a  physiologically  continuous  tract  arises 
which  passes  through  the  fields /i,/2  (Fig.  3)  into  the 
arcuate  fasciculi  (arc^  Figs.  3  and  ^),  decussating  in  the 
piniform  decussation,'  and  after  crossing  the  median  line 
continuing  brainward,  in  the  interolivary  stratum  of  the 
oblongata  and  pons  (/,  Fig.  3). 

As  m  cases  of  prolonged  typical  locomotor  ataxia  the 
columns  of  GoU  undergo  secondary  degeneration,  it  is 
to  be  assumed  that  the  essential  primary  lesion  of  that 
disease  affects  the  nutrition  of  those  columns  secondarily 
either  by  the  involvement  of  the  posterior  rootlets  or  of 
the  gray  substance  in  which  they  terminate  or  through 
which  they  pass.'  The  connection  of  the  column  of 
GoU  with  the  sensory  nerves  of  the  inferior  extremity  has 
been  positively  established.  It  is  evident,  then,  that  the 
column  of  GoU  conveys  brainward  certain  impressions 
which  occur  in  the  posterior  (inferior)  half  of  the  body. 
It  is  exceedingly  probable  that  those  impressions  which 
are  most  regularly  affected  in  locomotor  ataxia,  namely, 
diose  informing  the  subject  of  the  position  of  his  lower 
limbs  in  space,  which  enable  him  to  regulate  their  mus- 
cular movements  in  conformity  with  the  resistance  to  be 
overcome,  and  which  are  ordinarily  classed  under  the 
head  "muscular  sense,"  are  the  ones  conducted  by  these 
columns.  In  order  to  become  appreciated,  however, 
these  columns  must  be  connected  with  higher  centres 
than  the  nuclei  of  GoU  and  Burdach ;  the  regulation  of 
these  movements  which  are  most  constantly  affected  in 
locomotor  ataxia,  while  not  altogether  removed  from 
cerebellar  control,*  is  a  function  of  the  cerebral  hemi- 
spheres. It  is  evident,  therefore,  that  after  interruption — 
for  some  thus  far  inscrutable  purpose — in  the  nuclei  of 
Burdach  and  GoU,  another  tract  must  leave  these  sta- 
tions to  reach  the  cerebrum.  This  tract  is  the  one  just 
described  and  visible  in  its  decussation  in  Figs.  3  and  4, 
that  is,  the  interolivary  layer  of  Flechsig. 

Meynert  long  ago  recognized  the  necessity  of  estab- 
Ushing  a  connection  between  the  posterior  columns  of 


>  From  the  supposed  connection  with  Meynert*s  stratum  tHtermedium  I  ap- 
plied that  nsune  to  the  interolivary  extension.  I  have  resolved  for  the  present  to 
discontinue  its  emplojnnent,  as  the  same  designation  has  been  employed  in 
such  different  ways  by  Wernicke  and  Meynert  hunself. 


sup- 


■  Upper  fine-bundled  or  sensory  decussation  of  the  pyramids  of  Meynert 
*  It  has  been  lately  shown  that  the  columns  of  Clarke,  which  are  by  F  lechsie  __^ 
posed  to  have  a  reUiion  to  the  posterior  rootlets,  are  similarly  involved  m  ad< 
vanced  cases  of  this  disease. 

^  On  oomparinc  a  number  of  types  of  this  disease  it  will  be  found  that  in  some 
the  ataxia  has  an  actual  cerebellar  character,  hut  in  others  noL  In  the  latter  the 
same  complaint  found  in  cortical  ataxia^  that  distance  is  misjudged  or  the  length 
«f  the  limb  or  a  segment  of  it  seems  increased  or  decreased,  is  made. 


the  spinal  cord  and  the  cerebrum.  The  method  he  foU 
lowed  in  delineating  his  projection  system  was  to  take 
physiological  and  pathological  facts  as  so  many  guides  in 
the  labyrinth  of  cerebral  fibre-tracts,  and  then  to  fit  the 
demonstrable  nerve-strands  that  happened  to  corre- 
spond, as  he  supposed,  to  the  required  physiological 
paths  into  the  maps  thus  constructed.  Knowing  that  the 
posterior  part  of  the  internal  capsule  conveyed  sensory 
functions,  and  that  the  posterior  columns  of  the  cord  did 
likewise,  he  traced  the  required  connection  between  them 
through  his  so-called  upper  or  sensory  pyramidal  decus- 
sation  into  the  lateral  part  of  the  pyramids,  along  these 
into  the  lateral  part  of  the  pes  pedunculij  and  thence  by 
an  easy  transition  into  the  posterior  division  of  the  in- 
ternal capsule.  A  diagram  representing  this  supposed 
tract  is  extant  in  Huguenin,  whose  work  is  in  the  mam  a 
popularization  of  Meynert's  system,  and  in  many  places 
evidently  inspired  l)y  the  black-board  diagrams  which 
this  great  master  of  modern  cerebral  anatomy  iUustrated 
his  lectures  with. 

Grossly  erroneous  as  Meynert's  representation  just 
detailed  is  now  known  to  be,  in  many  features  it  is  cor- 
rect ;  and  this  has  been  (intentionally  or  uninteiitionally) 
overlooked  by  those  who  have  condemned  his  views. 

It  is  a  fact  that  the  continuation  of  certain  portions  o( 
the  sensory  tract  from  the  cord  to  the  brain  decussates, 
in  the  upper  fine-bundled  decussation  called  by  Meynert 
the  "upper  decussation  of  the  pyramids."  The  view 
held  to-day  differs  from  Meynert's  chiefly  in  regard  to 
topographical  nomenclature*:  i.  As  the  decussation  m 
question  is  not  connected  with  the  pyramid  tract  proper, 
it  is  no  longer  called  che  upper  "  pyramidal "  decussa- 
tion. Flechsig's  followers  might  perhaps  term  it  the 
**  decussation  of  the  interolivary  stratum."  In  want  of 
any  other  brief  designation,  and  recognizing  that  it  could 
no  longer  be  considered  a  part  of  the  pyramidal  decussa- 
tion, I  termed  it  the  piniform  decussation.'  Certainly  it 
resembles  in  section  nothing  so  much  as  a  fir-cone  (Fig. 
4,  near  r  \  Fig.  3,  near  Dr).  2.  Meynert  was  partly 
correct  in  tracing  the  fibres  of  this  decussation  to  the 
lateral  part  of  the  pyramids,  as  these  bodies  were  consid- 
ered at  the  time  he  wrote  his  treatise.  The  pyramid 
tract  of  to-day  covers  a  much  more  limited  area  than  the 
one  assigned  to  it  by  anatomists  of  the  last  decade. 
Even  Henle,  who  wrote  after  Meynert,  represents  them 
as  extending  dorsad,  between  the  raphe  and  the  roots  of 
the  twelfth  pair,  nearly  to  the  floor  of  the  fourth  ventri- 
cle, making  them  include  the  strata  interolivaria  and  the 
inner  division  of  the  reticular  field  of  Mc3mert.*  3.  Even 
as  the  pyramids  are  demarcated  to-day  there  is  some 
little  justification  for  Meynert'^s  theorem.  Fibres  frm 
the  nuclei  of  GoU  and  Burdach  do  pass  into  a  field  con- 
nected with  the  true  pyramid  tract  I  expressed  a  sur- 
mise to  this  effect  in  the  description  of  the  case  of  sec- 
ondary degeneration  repeatedly  referred  to  in  the  course 
of  this  paper.  It  was  doubtful  to  me  then  whether  the 
fibres  thus  traced  by  their  degeneration  {Ds*^  Fig.  3)  rep- 
resented a  communication  of  the  interolivary  and  the 
pyramidal  tracts,  or  whether  they  were  the  fibres  which, 
leaving  the  pyramids,  pass  to  the  hypoglossal  nuclei,  and 
(subjected  to  the  pressure  of  the  shrinking  field  of  the 
interolivary  layer  through  which  they  passed?)  under- 
went a  slight  retrograde  degeneration.'  Opposed  as  this 
latter  alternative  appeared  to  be  by  the  general  rule  sup- 
posed to  govern  secondary  degenerations,  it  became  defi- 
nitely disposed  of  to  my  mind  after  a  complementary 
study  of  secondary  degeneration  of  the  pyramidal  tracts. 
Not  only  is  it  impossible  to  trace  degenerated  fibres  io 
the  hypoglossal  nuclei  in  any  such  situation  as  that  indi- 
cated by  Ds*,  but  the  very  fasciculi  within  the  pyramid 

»  Architecture  and  Mechanism  of  the  Brain,  Chicago  Toornal  of  Nenwos  sad 
Mental  Diseases,  1879,  1880, j- 

«  It  is  only  on  this  assumption  that  his  desipation  of  the  mesal  aocessonrow* 
as  a  "  nucleus  pyramidalis  ^'  is  comprehensible.  ^^, 

•  A  Coniribution  to  the  Morbid  Anatomy  of  Pons  Lesions  :  being  No^  ?«» 
III.,  of  Contributions  to  Neuropathology,  based  on  researches  cooduettj"  "J 
author's  laboratory.  Reprinted  from  the  American  Journal  of  NeoromT  ■» 
Psychiatry  for  November,  x883.»! 


October  i8,  1884.] 


THE  MEDICAL  RECORD.'^ 


•423 


field  which  are  affected  in  degeneration  of  the  interolivary 
stratum  were  found  comparatively  normal  in  a  case  of 
intense  double  descending  -,  degeneration  of  the  pyramid 
tracts.^  Whether  these  fibres,  after  leaving  the  inter- 
olivary layer,  re-enter  it,  abandoning  their  intra-pyramidal 
course,  I  am  at  present  unable  to  determine.  But  the 
fact  here  stated  shows  that  -there  was  much  more  basis 
for  Meynert's  view  than  .  Flechsig  seem  to  have  been 
aware  of. 

Flechsig  assumes,  for  the  sake  of  simplifpng  matters, 
that  the  fibres  of  the  posterior  columns  which  represent 
the  cephalic  continuation  of  the  posterior  roots  of  the 
spinal  nerves  abut  in  the  nuclei  of  the  columns  of  Goll 
and  Burdach,  without  committing  himself  directly  to  the 
view  that  all  of  them  do  so.  If  we  believe  that  the  laws 
of'secondary  degeneration  are  invariable,  that  the  course  of 
such  degeneration  is  always  in  the  direction  of  functional 
transmission,*  then,  undoubtedly,  the  columns  of  Goll  and 
Burdach  must  terminate  in  the  nuclei  named  after  them, 
with  that  portion  of  their  fibres  which,  in  my  opinion, 
represent  Flechsig's  interolivary  layer  continued  down 
Rafter  nuclei  interruption) ;  for  in  my  case  of  a  secondary 
degeneration  of  six  years'  duration  not  a  degenerated 
6bre  could  be  traced  beyond  the  nuclei,  though  these 
themselves  were  atrophic. 

In  speaking  of  these  fibres,  Flechsig  battles  with  an 
imaginary  opponent.  He  says,*  "  The  view  that  the  pos- 
terior columns  pass  to  the  cerebrum  chiefly  through  the 
mediation  of  the  interolivary  layer  (and  the  longitudinal 
fibres  of  the  reticular  formation  ?)  has  much  more  in  its 
favor  than  the  view  that  the  posterior  columns  are  exclu- 
sively connected  with  the  cerebellum."  He  does  not 
inform  us  who  announces  such  a  view.  The  one  gener- 
ally held  up  to  the  time  of  Flechsig's  writings,  was  that 
of  Meynert,  who  traced  a  part  of  the  posterior  columns 
(correctly)  to  the  cerebellum,  and  another  portion  to  the 
cerebrum,  through  his  so-called  '*  tipper  fine-bundled  de- 
cussation of  the  pyramids."  Flechsig  was  destined  to 
confirm  this  view  of  Meynert's,  with  some  toponomical 
corrections  above  referred  to,  to  demonstrate  much  more 
satisfactorily  than  Meynert  ever  dreamed  of  doing  that 
this  decussation  embodied  the  continuation  of  posterior 
column  fibres,  and  to  correct  some  erroneous  details  in 
Meynert's  scheme.  All  this  does  not  justify  his  repeated 
innuendoes  against  the  latter  on  the  one  hand,  and  the 
suppression  of  its  meritorious  features  on  the  other.  In- 
deed, it  would  not  be  difficult  'to  show  that  if  Flechsig 
does  not  owe  to  Meynert  the  hint  which  led  to  his  follow- 
ing the  embryological  method  with  such  signal  and  ac- 
knowledged success,  he  would  be  compelled  to  confess 
to  having  had  but  an  imperfect  knowledge  of  the  cerebral 
anatomical  literature  extant  when  he  undertook  his  great 
work.* 

The  ** atrophy  method,"  and  the  "development 
method  "  of  Flechsig  have  undoubtedly  cleared  up  much 
in  the  cerebral  labyrinth  which  other  methods  were  in- 
adequate to  imravel ;  and  if  it  be  true,  as  I  have  repeat- 
edly stated  to  my  class,  that  the  progress  made  in  cere- 
bral anatomy  during  the  last  ten  years,  quantitatively 
speaking,  exceeds  that  made  during  the  previous  one 
hundred  and  fifty  years,  it  is  to  these  two  methods  that 
the  credit  is  chiefly  due.  But  while  recognizing  the  ser- 
vice which  Gudden,  Flechsig,  and  their  pupils  have 
done  and  are  doing,  it  is  not  yet  demonstrated  that  their 

^  This  I  found  to  b«  as  described  in  sfwcimens  of  another's  unpublished  case  of 
descending  degeneration  of  both  pyramid  tracts,  and  in  a  unilateral  case  of  my 
#wn. 

•  Which  is  not  the  case.  »  Plan  of  the  Human  Brain,  p.  aa. 

^  For  in  the  following  lines  is  contained  the  suggestion  and  essential  feature  of 
Fkcfasig's  method,  and  one  of  his  conclusions  unperfcctly  expressed ;  indeed, 
Flechsig  knew  of  them,  referring  to  them  in  his  book  ;  recognizing  that  Meynert 
IS  the  first  to  suggest  that  the  development  of  myelin  m  the  nerve-tracts  was  des- 
tined to  reveal  important  features  of  the  development  and  structure  of  the  central 
nervous  sjrstenu  "The  absence  of  the  striae  acusttci  in  all  animals  does  not 
mdicate  an  absence  of  its  nervous  bundles,  but  only  the  invisibility  of  these  due  to 
thdr  axis  cylinders  being  unprovided  with  the  myelin  sheath.  The  development 
of  myeUn  corresponds  to  the  acme  of  cerebral  evolution,  hence  their  absence  in  the 
new-born  and  their  greater  frequency,  according  to  J.  Engels,  in  the  bodies  of 
adults.  For  the  same  reason  the  pes  pedunculi  of  the  new-bom  is  gray  instead 
•fwkiU.  The  Mnsimultanetms  development  of  the  medullary  white  in  dijffer- 
■**'  Pnrts  0/  the  brain  is  indeed  a  mast  important  subject  ^or  searching' 
study  "  (Stridcer's  Collection,  vol.  ii.,  pp.  770-71). 


methods  are  as  exact  as  their  advocates  allege.  To 
show  the  justice  of  this  doubt  it  would  suffice  for  me  to 
refer  to  the  various  controversies  which  Mayser  and  Forel, 
on  the  part  of  the  Gudden  school,  and  Flechsig  have  in- 
dulged in.  The  results  derived  by  both  methods  ought 
to  be  identical,  if  both  were  absolutely  correct.  They 
differ,  however,  in  some  respects  and  several  details ; 
and  notwithstanding  that  it  has  been  implied — and  par- 
ticularly by  one  who  has  undertaken  to  interpret  and  re- 
port the  results  of  industrious  continental  laborers,  after 
a  hurried  visit  to  their  laboratories — that  the  day  of  mi- 
croscopic sections  is  past,  I  believe  that  neither  the  re- 
sults of  the  atrophy  method  nor  those  of  the  embryonic 
method  should  be  accepted  unless  they  are  gauged  by  a 
study  of  sections  and  made  to  harmonize  with  their  rev- 
elations.* 

In  order  to  show  that  those  who  have  most  severely 
criticised  Meynert,  and  at  the  same  time  most  sedulously 
belittled  the  extent  of  our  indebtedness  to  him,  are  not 
themselves  free  from  errors,  often  far  more  serious  than 
those  committed  by  that  authority,  I  will  refer  for  a 
moment  to  the  latest  proclamations  made  by  Flechsig 
regarding  the  cerebellum. 

Flechsig  is  undoubtedly  justified  in  attaching  great  im- 
portance to  the  peculiarities  of  tract  development,  ob- 
served in  a  child  born  without  a  cerebellum.  It  is  diffi- 
cult to  understand,  however,  how  he  can  state :  "  This 
brain  united  the  advantages  of  developmental  and  degen- 
erative differentiation  of  the  central  white  masses,  inas- 
much as  all  fibre-tracts  connected  with  the  cerebellum 
were  absent  or  atrophic,  while  all  others  were  developed 
to  an  extent  corresponding  to  the  end  of  the  period  of 
foetal  life,  being  partly  myelinic  and  in  part  amyelinic." 
The  cerebellum  is  too  important  an  ingredient  of  the 
central  mechanism  to  be  eliminated  without  producing 
far-reaching  defects  in  development -elsewhere.  It  is  not 
probable  that  the  remote  centres  connected  with  the 
cerebellum  were,  as  such,  normally  developed  ;  the  men- 
tal disturbance  noted  with  defective  development  of  the 
cerebellum  is  probably  to  be  explained  on  the  ground 
that  its  absence  is  associated  with  other  defects,  indeed, 
that  it  is  only  an  intensified  expression  of  a  general  defect 
in  cerebral  development.  This  is  the  proper  explana- 
tion of  the  intellectual  deficiency  noted  with  cerebellar 
atrophy,  and  not  the  wild  and  startling  tentative  sugges- 
tion of  Flechsig,*  who  asks  whether  the  existence  of  the 
commisural  cortical  gray  of  the  cerebellum  does  not  ex- 
plain (by  vicariation)  the  absence  of  mental  disturbance 
noted  in  cases  where  the  corpus  callosum  is  absent ! 
This  suggestion  exceeds  in  fancifulness,  and  in  lack  of 
foundation,  anything  ventured  by  Meynert,  who  is  harshly 
criticised  by  Flechsig,  but  who  rarely  abandoned  the 
channels  of  logi  il  reasoning  based  on  the  facts  as 
known,  or  supposed  to  be  known,  in  his  day,  to  such  a 
grievous  extent,  at  least  not  before  Flechsig  wrote. 

It  is  an  interesting  and  important  question,  one  requir- 
ing great  care  and  a  comparison  of  numerous  anatomical 
and  experimental  facts  to  determine,  what  qualities  of  sen- 
sation are  transferred  to  the  brain  by  the  piniform,  or 
upper  (sensory)  decussation  of  the  interolivary  stratum. 
Wernicke "  first  formally  considered  the  inconsistency  be- 
tween the  well-known  phenomenon^  of  crossed  hemi- 
anaesthesia  in  spinal  hemisection  and  the  assumption  of 
a  redecussation  in  the  oblongata.  Many  who  have  neve  r 
published  their  doubts  probably  raised  the  above  questio  i 
in  their  minds.  More  recently  Starr  *  has  reviewed  th  • 
entire  question  and  collected  a  number  of  valuable  an  I 
not  generally  accessible  cases,  which  justify  his  arriving  rt 

^  I  refer  here  only  to  studies  made  on  the  human  subject,  when  speaking  of  a*.  - 
tual  discrepancies. 

*  Plan  of  the  Human  Brain,  page  4a,  foot-ndte.  It  may  serve  to  show  that  the 
day  of  speculation  as  to  this  terra  incognita  of  hnin  anatomy  is  far  firom  waning, 
that  while  Flechsig  suggests  a  possible  vicariation  of  the  cerebellum  for  deficiency 
of  the  intellectual  of^an  par  ejccellence,  Starr*  with  all  the  well-established  facts 
elucidated  by  Flrchsig  at  his  disposal,  concludes  that  it  is  in  part  a  centre  con- 
nected with  vegetative  life  (The  Sensory  Tract  in  the  Central  Nervous  System, 
Alumni  Prize  Essay,  College  of  Physicians  and  Surgeons,  by  M.  Allen  Starr). 

*  Lehrbuch  der  Gehimkrankheiten,  ed.|I.,  x88i.  Not  in  American  hands  till 
1883.  *  Ix)c.  cit.,  p.  52. 


424 


THE  MEDICAL  RECORD. 


[October  i8, 1884. 


conclusions,  as  he  supposes,  very  dififerent  from  those  of 
Wernicke  and  my  own ;  *  my  own  position  having  been  to 
some  extent  misapprehended  by  Starr,  as  he  has  since 
recognized  in  a  note  to  the  Journal  of  Nervous  and  Men- 
tal Diseases^  in  which  his  article  appeared.  With  regard 
to  Wernicke,  I  think  he  has  fallen  into  a  similar  misun- 
derstanding. He  8a3rs  that  his  results  of  a  study  ot  cases 
is  opposed  to  the  course  of  the  sensory  tracts  as  described 
by  Wernicke,  for  several  reasons,  among  them,  because 
« these  tracts  are  supposed  to  leave  the  medulla  and  to 
pass  by  way  of  the  cerebellum  to  the  pons."  The  further 
text  of  his  article  shows  that  Starr  attributes  to  Wernicke 
the  view  that  all  sensory  tracts  pass  by  way  of  the  cere- 
bellum, and  none  by  way  of  the  pons.  In  reality  Wernicke's 
position  is  very  conservative,  he  discusses  the  entire 
question,  and  concludes  that  there  are  several  possible 
channels  by  which  sensory  paths  may  reach  the  cerebrum, 
which  he  details  under  the  headings  I.  and  II.,  A.  (a  and 
b)y  B.  {a^  b,  c).  Of  these,  all  but  the  first  are  enumerated 
by  Statr,  who  implies  that  Wernicke  rejects  the  alterna- 
tive under  I.,  namely:  a  path  of  single  decussation  (running 
through)  the  most  lateral  portion  of  fibres  of  the  lateral 
"motor"  field  of  the  tegmental  part  (of  the  oblongata  and 
pons),  then  above  the  exit-level  of  the  trigeminus  in  the 
neighborhood  of  the  ascending  trigeminus  root,  (situated) 
in  the  spinal  cord,  in  the  **  lateral  layer  bounding  the  gray 
substance,"  (then) "decussation  in  the  gray  substance  im- 
mediately above  the  respective  posterior  roots.* 

I  do  not  think  that  the  language  of  Wernicke  on  page 
262,  where  he  discusses  his  own  and  Kahler's  case, 
necessarily  implies  the  interpretation  Starr  has  given  to 
it.  If  so,  it  is  difficult  to  see  why  Wernicke  should  enu- 
merate the  above  tract  in  his  conclusions.  He  simply 
discusses  a  number  of  "  important  considerations  and 
doubts,"  ■  which  are  encountered  by  him  in  his  attempt 
to  consider  the  tract  mentioned  as  the  one.  In  the  very 
paragraph  where  he  expresses  these  doubts  he  says  that 
'*  there  must  be  separate  (distinct)  sensory  paths  in  the 
oblongata,"  a  conclusion  at  which  I  arrived  some  years 
ago,*  and  which  seems  to  me  to-day  to  be  the  only  one 
that  can  be  harmonized  with  those  facts  stated  in  the  in- 
roductory  remarks  of  the  present  paper.  Starr's  con- 
clusion as  to  the  course  of  the  tracts  for  tactile  perception 
repeats  the  hypothetical  tract  deduced  by  Wernicke  in 
very  many  particulars.  The  doubts  which  troubled  Wer- 
nicke are  based  on  facts  which  have  not  been  disputed 
to  this  day.  They  are  as  much  a  subject  for  considera- 
tion now  as  then. 

The  collection  of  cases  made  by  Starr  is  accompanied 
by  the  following  conclusions  (p.  61)  :  "Those  sensory 
impulses  which  have  not  decussated  in  the  spinal  cord 
cross  the  median  line  in  the  sensory  decussation  of  the 
medulla,  and  pass  upward  through  the  interolivary  tract 
to  the  lemniscus,  in  which  they  ascend  to  the  internal 
capsule.  These  are  the  sensations  included  under  the 
term  muscular  sense."  This  proposition  would  seem  to 
be  as  well  based  as  the  dictum  that  lesion  of  the  motor 
tract  in  the  internal  capsule  produces  contralateral  pa- 
ralysis. The  cases  of  K  abler  and  Pick,  Meyer,  Senator, 
and  my  own,  cited,  prove  that  lesion  of  one  interolivary 
layer  produces  contralateral  ataxia ;  indeed,  in  my  case 
the  anatomical  proof  of  the  decussation — the  degenera- 
tion crossing  in  the  direction  of  functional  involvement — 
was  as  complete  as  the  clinical  evidence.  This  fact  is 
furthermore  in  harmony  with  a  statement  of  Brown  S6- 
quard,  that  in  his  puzzling  symptoms  of  spinal  hemisection 
the  muscular  sense  does  not  follow  the  rule  of  spinal  de- 
cussation, but  suffers  on  the  same  side  with  the  motor 
function.     If  Ferrier's  recent  contradiction  *  of  Brown- 

>  The  Sensory  Tract  to  the  Fore-brain,  note  in  the  Chicago  Medical  Review, 
July  13,  z88z  ;  and  Morpholos^ical  Relations  of  the  Cerebellum,  ibid.,  July  5th. 

•  Wernicke :  Loc.  dt,  vol.  1.,  p.  265,  lines  ia-17. 

•  **  Wichtige  Bedenken/*  *'Bedenken''  is  best  rendered  as  a  mixture  of  **  reflec- 
tion" and  '*aouDt,*'  for  which  there  is  no  accurate  equivalent  in  English  ;  it  implies 


«  Architecture  of  the  Oblongata,  New  York  Medical  Journal,  September.  i88z. 
The  view  of  separate  tracts  tor  muscular  and  -tactile  sense  is  expressed  m  this 
articl«^  but  has  been  much  modified  in  detail  since. 

*  He  claims  that  the  muscular  sense  path  decussates  in  the  cord. 


S^uard's  theorem  stands,  then  we  are  in  the  same  qoan. 
dary  as  before  with  regard  to  the  alternative  stated  by 
Wernicke,  that  if  the  sensory  paths  all  decussate  in  the 
oblongata,  they  must  redecussate  twice  in  the  cord,  if  the 
facts  of  capsular  and  spinal  hemianaesthesia  are  to  be 
harmonized. 


Fig.  5. 


As  far  as  the  tract  we  are  now  considering  is  traced 
from  the  nuclei  of  Burdach  and  Goll  to  the  anterior 
(cephalic)  end  of  the  pons  is  concerned,  our  knowledge 
is  very  satisfactory.  Above  this  point  it  is  involved  in 
some  obscurity.      Flechsig  believes  that  a  part  of  the 


men ' 


%IS@»  7        He 


IFiG.  7. 


Fig.  6. 

lemniscus,  as  far  as  I  can  glean,  the  one  he  believes  to 

correspond  to  our  tract,  passes  directly  into  the  interoal 

capsule.     This  would  appear  to  be  the  simplest  solution. 

Elsewhere  he  states  that  fibres  derived  from  the  puta- 

and  the  nucleus  caudatus,  after  coursing  through 

_  _         the    internal    capsule,   pass 

j^^Bfew^  ^rf-f^ff^  through  the  dorsal  part  of  the 

g-  ■        ^^^^-m^^-  ^'\  p^g  pedunculi,  being  crowd- 

against  and  pressed  be- 
tween the  ventro-lateral  pro- 
cesses of  the  substantia  nigra. 
He  considers  it  possible  that 
this  fasciculus  is  connected 
with  the  substantia  nigra, 
for  a  large  portion  of  it  be- 
comes lost  here.  The  remainder  he  traces  cordward 
as  a  ventro-medial  accompaniment  of  the  lemniscus 
layer,  and  supposes  that  it  is  ultimately  united  with  the 
gray  matter  of  the  pons.  This  tract  degenerates  in  the 
descending  direction  when  diseased  in 
the  adult.  Elsewhere  *  he  speaks  of 
the  same  fibres  as  intruding  themselves 
between  the  lemniscus  layer  and  the 
raphe  "lower  down,"  and  as  leaving 
the  pes  to  enter  the  tegmentum.  Cer- 
tainly his  first  declaration,  as  to  a  prob- 
able connection  with  the  nucleos 
pontis,  is  contradicted,  not  alone  by 
the  second  statement,  viz.,  that  it  passes  into  the  teg- 
mentum, but  also  by  the  course  of  the  tract  as  indicate 
in  his  diagram,  which  is  made  to  run  quite  parallel  with 
his  "  interolivary  layer,"  and  into  it. 

The  interolivary  layer  of  Flechsig  is,  according  to  him, 
the  continuation  of  the  interolivary 
layer  upward.  Two-thirds  of  this  fibre 
system  is  represented  in  that  part  of 
the  interolivary  layer  which  is  in  im- 
mediate contact  with  the  olives.  He 
adds,  with  a  query  of  his  own,  "aiid 
Fig.  9.  has  no  (?)  connection  with  the  upper 

pyramidal  decussation."    This  query  was  certainly  a  sav- 
ing afterthought     The  secondary  degeneration  described 

» The  outer  of  the  three  (or  four,  and  in  some  subjects  five)  "  artknli "  of  the  !«■• 
tkular  nucleus.  ^  Plan  of  the  Human  Brain,  p.  so> 


Fig.  8. 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


425 


in  a  case  of  pons  lesion  by  myself  appears  to  dispose  of 
this  question.  In  it  the  degeneration  was  limited  to  that 
very  portion  of  the  interolivary  layer,  and  the  corre- 
sponding half  of  the  upper  pyramidal  decussation  was  al* 
most  entirely  eliminated. 

Another  statement  of  Flechsig's  demonstrates  that  he 
has  confounded  the  relations  of  the  two  divisions  he 
has  made.  He  says  the  smaller  division — that  is,  the 
part  remaining  of  the  lemniscus  after 
the  larger  portion  adjacent  to  the  olive 
is  subtracted — is  connected  with  the 
upper  p)rramidal  decussation,  and  that 
its  fibres  do  not  degenerate  for  any 
distance  downward."  Now,  it  is  the 
very  part  which  does  connect  with  the 
pyramids,  but  which  lies  adjacent  to 
the  olives,  which  degenerates  down- 
ward (cordward)  for  its  entire  ana- 
tomical extent,  as  shown  in  the  dia- 
grams and  fac-similes  on  the  opposite 
page.  Flechsig  is  also  wrong  in  as- 
serting that  the  greater  part  of  the 
lemniscus  (two-thirds)  degenerates 
downward,*  giving,  as  he  does,  the  im- 
pression that  this  is  an  invariable  rule. 
In  my  case  the  ascending  degenera- 
tion monopolized  by  far  the  larger  lem- 
niscus field,  all  of  it,  in  fact,  with  the 
exception  of  that  innermost  portion 
which  some  authors  fail  to  include  in 
the  lemniscus  proper,  and  an  outer  part 
whose  position  is  not  well  set « led. 

Monakow  produced  descending  de- 
generation of  apparently  the  same 
field  which  Flechsig  terms  inter-olivary 
layer,  in  the  cat.  As  in  my  human 
case,  this  degeneration  underwent  a 
decussation,  chiefly  in  the  lower  oli- 
vary' plane  and  passed  into  the  nuclei 
of  the  columns  of  Goll,  which,  as  in  my  case  also,  were 
atrophic.  Monakow's  description  ■  of  this  tract,  which  de- 
generated after  destruction  of  the  parietal  lobe,*  following  a 
course  through  the  external  and  posteriornucleiof  thethal* 
amus  into  the  dorsal  part  of  the  subthalatiiic  region,  cor- 
responds more  closely  to  the  appearances  found  in  my 
case  than  do  any  of  Flechsig's  delineations  and  declara* 
tions.  The  correspondence  between  the  results  obtained 
by  the  atrophy  method  in  the  cat,  and  previously  by  my 
self  in  a  case  of  secondary  degeneration,  herein  repeatedly 
referred  to,  are  so  close  that  I  may  be  permitted  to  de- 
tail some  anatomical  facts  observed  in  the  lion,  the  dog, 
and  the  cat,  in  sections  prepared  by  means  of  the  bi- 
chromate of  potash  hardening,  microtome  cutting,  and 
carmine  staining  methods,  as  bearing  on  the  presumable 
course  of  this  part  of  the  lemniscus  tract  in  man.  The 
advantage  of  a  study  of  these  animals  is  that  the  pyramid, 
pons,  and  pes  are  small,  and  particularly  that  the  pons 
fibres  do  not,  as  in  man,  crowd  the  tegmentum  dorsad, 
compelling  certain  of  its  tracts  to  follow  as  arched  a 
course  as  in  man  ;  this  is  a  source  of  much  confusion  to 
the  topographical  anatomist. 

In  a  section  made  flat-wise  through  the  brain  axis,  that 
is,  parallel  to  the  basi-cranial  ideal  plane,  in  the  dog,  the 
intricate  relations  indicated  in  Fig.  lo  are  exposed,'  In 
the  latitude  of  the  trapezium  (23)  a  faint  sagittal  streak 

»Loc  dt^p.  a6. 

'  In  speakinif  of  the  olive,  I  refer  to  the  olive  par  exc^U^nct^  the  one  in  the  oh- 
wnKMa  ;  tfie  so-called  *•  upi>er  olive,"  I  term  the  nucleus  of  the  trapeduto. 

'  Kxperimental  Contributions  to  Our  Knowledge  of  the  ryramid  and  LemisiE- 
ai«  Tractm  by  v.  Monakow,  Correspondenzblatt  f.  Sdiweiier  Aente,  1884,  Nos*  6 
and  7,  per  Mendel's  Centralblatt,  May  i,.  1884. 

^  Hot  necessarily  homologous  with  Uie  same  lobe  in  man. 

•There  is  a  comical  resemUanoe  between  the  figure  wnen  Inverted^  and  <he 
bead  of  a  bull  or  bear,  and  when  upri[|^ht  that  of  an  elephant.  The  former  may 
v^itate  a  topographical  understandmg.  The  snout  of  the  hull  is  ihe  oiivt?- 
pyramidal  region,  toe  nostrils  being  represented  by  the  m^iln  or  d  tula  re  niicleua 
«f  the  olive  (a8),  the  eyes  with  the  lids  are  represented  by  the  nuclei  of  the  tx^ 
PCBum  or  superior  olives  (aj,  aa),  the  ears  by  the  p0HUi  brackiunt  or  middle 
jwebdlar  peduncle  (aO,  and  for  horns,  lovers  of  the  fanciful  may  tate  their  choice 
Mtveen  17  and  iq.  The  bulk  of  the  head  comprises  the  Erapcjium  and  pt>n&»  tht^ 
nedc  IS  equivalent  to  the  mesencephalo-crural  region. 


on  either  side  indicates  the  interolivary  layer  fax),  the 
oblongata  portion  of  which  is  seen  (27)  mesad  of  the 
dentoliva  (28).  There  appears  to  be  a  ganglionic  inter- 
polation between  it  and  the  major  part  of  the  lemniscus 
(26).  Now,  instead  of  sweeping  to  the  side  in  the  pons, 
lo  pass  into  the  L  shaped  lemniscus  field  of  the  mesen- 
cephalon ^  the  interohvary  layer  is  seen  to  occupy  a  dis- 
tinct field,  buried  in  the  nuclear  substance  of  the  pons 


(15),  and  clearly  traceable  into  a  field  which,  containing 
the  roots  of  the  oculo-moCor  nerve  (7),  must  lie  ventrad 
of  the  ocLilo-motor  nuclei,  indeed,  very  near  the  basis 
cruris.  This  fit;ld  {5,  6,  7,  8,  9,  on  the  left  side)  is  one 
that  has  yet  to  be  studied.  It  would  appear  to  pass,  in 
part  directly,  in  part  indirectly,  into  the  internal  capsule 
(so,  r,  15,  indicating  the  course  of  the  outer  part  of  the 
crus  toward  it).  A  direct  fasciculus  is  seen  at  11*  Be- 
sides the  direct  tract  from  the  interolivary  layer  (15,  9) 
it  receives  fibres  from  the  inverted  forceps-shaped  field 
(14),  Whether  all  the  fibres  continue  uninterruptedly 
through  the  entire  extent  of  the  large  area  covered  by 
this  section  cannot,  of  course,  be  determined.  But  the 
appearances  are  very  much  that  way.  The  intimate 
connection  between  the  pyramid  tract  and  the  inter- 
olivary layer,  which  I  indicated,  finds  its  repetition  in 
an  apparent  anastomosis  of  pedal  fibres  with  the  inter- 
olivary continuation  upward  (the  unnamed  pale  field 
crossed  by  pointer  14  on  the  right  side,  symmetrical  to 
end  of  pointer  8)*  The  relations  of  this  part  to  the  sub- 
stantia nigra  is  interesting,  but  the  main  part  certainly 
passes  through  without  interruption. 

In  the  human  brain,  owin^  to  the  causes  mentioned, 
the  relations  arc  not  so  sim]>le.  The  appearances  are, 
however,  against  the  view  that  the  interolivary  layer 
passes  exclusively  into  the  field  known  as  the  lemniscus ; 
the  bundle  from  the  pes  to  the  tegmentum  appears  lo  be, 
in  part  at  least,  connected  with  it.  In  Fig.  11,  which 
represents  a  section  taken  in  a  plane,  slightly  raised  dor- 
sally  in  front,  as  compared  with  Fig,  10,  the  interolivary 
layer  is  shown  in  as  complete  a  continuity  as  it  can  be, 
without  preliminary  distortion  of  the  brain  axis.  It  is 
here  seen  that  the  interolivary  lay er,  beginning  just  above 
the  pyramid  decussation  at  e^  passes  on  either  side  of  the 
raphe  «  r,  b^  a)  detaching  (apparently)  fibres  (at  7  and  6), 
which,  moving  out  more  and  more  laterad  (5),  reach  the 
lemniscus  field  of  the  mesencephalon  (4).    But  the  fibres 


426 


THE  MEDICAL  RECORD. 


[October  i8,  1884, 


hugging  the  middle  line  do  not  pass  into  this  field  at  a^ 
they  dip  ventrad  apparently  ;  this  is  the  locality  where 
so  much  confusion  prevails,  which  can  be  cleared  up  by 
filling  in  the  required  gap  with  the  tracts  9  and  14  of 
Fig.  10. 


Fig.  zi.—Section  in  Basilar  Plane  of  the  Brain  Axis  of  a  Sj'philidc  Subject.  (Autopsy  and  case  by  Prof.  James 
L.  Little.)  The  numerals  i  to  7  relate  to  the  lemniscus  tracts  in  ffeneral :  the  letters  a  to  /,  to  the  mesal  contin- 
uation of  the  interolivary  layer,  bundle  from  pts  to  tegmentum  of  Henle  (see  Part  ID:  ///,  posterior  part  of 
third  rentricle:  C.post,^  posterior  commissure ;  Aq,  Gr,^  gray  matter  surrounding  the  aqueduct :  //,  habenu* 
lar  bundle  :  mi  t  and  a,  tnalamic  laminse  ;  **,  unnamed  tract,  firom  analogy  with  a  and  4  of  Ki^.  10,  possiU^ 
the  capsule  seeking  j»art  of  the  interolivary  (muscular  sense)  tract ;  pl/.^  fKMterior  longitudinal  fasciculus :  C 
cerebu,^  Gratiole^s  direct  &sciculus  firom  the  cerebellum  to  the  cerebrum  :  *•  iu  cerebellar  origin  (nearly)  ;  Tegntt. 


_      .         ,.  .   Tegmtt. 
Br.  X.^  Wemekinck's  commissure  (?)  decussation  of  tfgmenta   brackium  {brackium  c^mt'tmcthmm) ;  Pant. 

'the  seventh  and  eighth  cranial 
r  nucleus  ;  />r.  A'.,  decussation  of  trua 


cranial  nerves ; 


,.,     „  ,  C#IK/«I 

Br.^  pientis  brackium^  middle  cerebellar  peduncle ;  rad.,  roots  of  the  seventh  and  eighth 
Oi.  int,,  internal  accessory  olive;  OL  dent.^  dentate  or  main  olivary  nucleus  ;  Fyr,  JC.,  Ate 
pyramids ;  pointer  5  is  in  Uie  direction  of  the  transverse  pons  fibres,  a  thin  veneer  of  which  has  been  cut. 


The  almost  direct  passage  of  the  main  part  of  the  lem- 
niscus toward  the  internal  capsule  is  well  seen  at  2  and  i. 

If  my  surmise  as  to  the  equivalence  of  the  unnamed 
tracty  indicated  by  the  double  asterisk,  with  those  indi- 
cated by  the  numerals  2  and  4  in  Fig.  10  be  correct,  it 
becomes  comparatively  easy  to  complete  the  channel  of 
the  muscular  sense.  In  the  accompanying  section  from 
a  monkey  (Fig.  12  ')  the  numerals  9  and  8  indicate  this 
tract  exposed  lengthwise ;  its  direction  is  clearly  to  the 
parietal  lobe.  It  becomes  apparent  how  Meynert  could 
erroneously  trace  this  bundle  to  the  occipital  lobes,  in 
less  fortunate  sections,  inasmuch  as  it  closely  skirts  the 
optic  radiation  of  Gratiolet.  The  direction  of  the  main 
(lateral  and  middle)  part  of  the  lemniscus  is  indicated  by 

1  For  this  animal  as  well  as  the  lion,  I  aai  indebltd  to  Dr.  Cooklin  of  the  General 
Park  Zoobgical  Department. 


the  numerals  25,  27,  and  28.     If,  as  is  surmised,  the  tract 
for  muscular  sense  (9,  6)  separate  from  the  cutaneous 
tract  (25,  27)  in  its  course  through  the  medulla  and  pons, 
becomes  united  to  or  intermingled  with  it  in  the  thalamo- 
lenticular division  of  the  capsule,  we  can  readily  under- 
stand  why  all  qualities  of  sensation 
would  be  affected  in  capsular  be- 
mianassthesia,   while  they   may  be 
separately  involved  in  the  pons  and 
oblongata.     The  close  proximity  of 
the  former  and  the  motor  tract  10 
would  be  consistent  with  the  fre- 
quently overlooked  disturbance  of 
the   muscular  sense  in  hemiplegia. 
The  tract-course  here  supposed  is 
I        consistent  with  v.   Monakow's   ex- 
frf  wr  periments,  and  justifies  the  designa- 
^       tion  of  Rinden-Schleife  (cortex  lem- 
nisais),  which  he  has  given  the  in- 
terolivary  tract 

As  satisfactory  as  the  picture  of 
the  interolivary  layer  is  in  sagittal 
jft/w/lfiVji^  sections  taken  through  its  pontine 
course,  as  difficult  is  it  to  identify 
every  corresponding  area  of  that 
course  in  transverse  sections.  In 
sagittal  section,  the  stratum  inter- 
medium (interolivare)  is  a  beautiful 
arched  fasciculus,  covering  Gall's 
ligne  de  separation  already  referred 
to  (Part  II.).  At  one  point  it  does 
not  appear  to  adhere  to  that  line, 
but  to  be  broken  up,  and  where  not 
broken  up  to  take  a  more  dorsal 
course.  This  portion,  however,  re- 
sumes the  characteristic  relations  in 
the  caudal  half  of  the  pons.  The 
deviation  corresponds  to  a  gangli- 
onic intercalation  described  by  Rol« 
ler,  which  is  reticular,  like  a  trellis- 
work.  It  is  found  at  the  point 
where  the  tegmentum  is  most  re* 
duced  in  its  dorso-ventral  diameter 
(owing  to  the  exclusion  of  the  teg- 
menta  brachium  and  the  inferior 
cerebellar  peduncles  from  this  field).* 
In  transverse  sections  at  this  level 
a  distinct  field  is  seen,  dorsad  of 
and  encroaching  on  the  trellis-work ; 
it  extends  to  the  raphe  and  overlaps 
the  mesal  end  of  the  horizontal 
lemniscus  field  ;  this  is  probably  the 
(diverted)  dorsal  part  of  the  inter- 
mediate tract. 

Every  specimen  in  my  possession 
indicates  that  a  large  part  of  this 
fasciculus  becomes  lost  in  the  sub- 
stantia nigra.  At  the  same  time  a 
portion  continues  directly  forward 
as  in  the  dog.  This  part  has  been 
regarded  by  Wernicke  *  as  a  bundle  from  the  pes  to  the 
lemniscus.  It  is  accurately  represented  in  Figs.  XIII.,  50,. 
52,  and  53  (pip')j  but  there  is  a  curious  inconsistency.. 
In  Fig.  48  he  represents  this  fasciculus  as  giving  oflf  the 
most  anterior  transverse  pons  fibres,  as  if  it  exhausted 
itself  in  their  formation,  while  in  the  level  above  and  be- 
low this  one  he  has  the  fasciculus  divided  transversely 
and  occupying  identical  situations.  He  has  undoubtedly 
confounded  it  with  another  bundle  in  this  section.  This 
bundle,  correctly  named  by  Wernicke,  lies  on  the  latero- 
dorsal  aspect  of  the  prepontine  fossa,  where  the  pes  is 
free  of  the  pons,  it  occupies  the  slope  on  each  side  of 
the  interpeduncular  depression.     As  Wernicke  in  Fig. 


>  The  projectioii'system  of  the  brain  axis  is  reduced  here,  through  the 
to  the  cerebellum  of  certain  tracts  from  above  and  bdow. 
•Lehrbucfa. 


r    . 

hi 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


427 


XII*  (ix  39)  terms  a  bundle  occupying  a  correspondini^ 
situation  the  ansa  lenticularis  (Linsenkernschlinge),  it  is 
possible  that  through  the  intervention  of  this  fasciculus 


Fig.  la.— Section  Diagonal  to  the  Sagittal  Plane,  Deviating  Laterad  above,  through  a  Monkey's  Brain. 
(X  »X')  '»  post-coniu ;  a.  4,  optic  radiations  of  Gratiolet  (hemianopsia  tract) :  3,  comu  ammonis ;  5,  tail 
of  caudate  nucleus  {cauiiex  corj^ris  stria  ti)  ;  d,  9,  muscular  sense  tract  (?)  :  8,  to,  posterior  part  of 
volunnry  motor  tract  (the  reader  must  not  be  misled  by  its  apparent  relation  to  the  posterior  part  of  the 
lenticular  nucleus,  which  is  not  touched  in  this  section  and  extends,  avoiding  this  plane,  mudi  farther 
bock)*:  iz,  la,  lenticular  nucleus  (putamenand  middle  articulus) :  14,  optic  chiasm  :  18,  ao,  as,  lemniscus, 
Sdds :  aa,  direct  myelo-cerebellar  tract :  a^  dentate  nucleus  of  cerebeUum  ;  a6,  geniculatum  mtemum  : 
7,  geniculatum  externum  ;  ay,  radiations  of  lemniscus  into  thalamic  laminx. 

it  reaches  the  higher  destination.  The  optical  appeax- 
ance  of  the  two  bundles  in  their  designable  course  is  dif- 
ferent 

(To  be  continued.) 


CORYZA    VASOMOTORIA    PERIODICA   ("HAY 
ASTHMA  ")  IN  THE  NEGRO. 

Wrra  SOME  Remarks  on  the  Etiology  of  the  Disease.* 

By  JOHN  N.  MACKENZIE,  M.D., 

SUBCBON  TO  THE   I'ALTIMORK  SVB,   BAK,  AND  THROAT  CHARITY  HOSPITAL. 

The  absence  of  so-called  '^  hay  asthma  "  in  the  negro  has 
been  brought  into  prominence  by  recent  writers  on  the 
subject,  and  notably  by  Beard,  as  an  argument  in  favor 
of  the  important  rdle  which  race  is  supposed  to  play  in 
the  etiology  of  the  disease.  The  following  case  derives 
its  peculiar  interest  from  the  fact  that,  so  far  as  I  am 
aware,  it  is  the  first  recorded  instance  of  the  afiection  in 
a  race  in  which  the  possibility  of  its  occurrence  has  been 
denied. 

J.  M ,  aged  thirty-five,  unmarried,  a  tall,  well- 
proportioned,  respectable  colored  man,  came,  September 
6,  1884,  to  my  clinic  at  the  hospital  to  be  treated  for 
"hay  asthma."  His  history  may  be  briefly  summed  up 
as  follows  :  He  has  always  been  remarkably  healthy,  with 
the  exception  of  a  tendency  to  catch  cold  upon  exposure 
to  the  most  trivial  exciting  causes.  Ever  since  his  ear- 
liest recollection,  the  emanations  from  hay  have  invari- 
ably excited  a  coryza  of  great  severity,  lasting  from  three 
to  seven  days  and  then  subsiding.  Handling  hay  at  any 
season  of  the  year,  or  even  unpacking  articles  enveloped 
in  straw,  always  bring  on  sneezing,  lachrymation,  flushing 
of  the  conjunctivae,  and  obstruction  of  the  nostrils.  For 
the  past  four  years  has  had  an  almost  constant  sensation 
of  "  stufl^ness  "  in  the  nostrils,  with  dyspnoea  on  exertion 
accompanied  by  a  slight  posf-nasal  discharge,  and  the 
attacks  of  coryza  have  become  much  more  frequent  and 
have  been  associated  with  distressing  asthma. 

The  attack  is  ushered  in  sometimes  by  a  tickling  or 
itching  sensation  in  the  upper  and  back  portion  of  the 
throat  and  nose,  sometimes  by  violent  sternutation.    The 

>  Read  before  the  Clinical  Society  of  Maryland,  October  3,  1884. 


nostrils  become  suddenly  obstructed,  a*  profuse  watery 
discharge  is  excited,  the  eyes  become  red,  swollen,  and 
painful,  and  the  lids  slightly  puffed.  There  is  always  in- 
creased lachrymation.  Cough  is  some- 
times present,  but  forms  an  unimpor- 
tant feature  of  the  paroxysm.  In  a  short 
while,  generally  in  the  course  of  an  hour, 
the  asthmatic  symptoms  supervene.  The 
extreme  dyspnoea  thereby  produced  ren- 
ders him  perfectly  helpless.  The  asthma 
is  worse  at  night,  so  that  during  the  pe- 
riod of  his  attack  he  gets  very  little  sleep, 
the  dyspnoea  often  amounting  to  or- 
thopnoea.  The  latter  is  relieved  after 
an  hour  or  more  by  violent  sneezing,  fol- 
^i  lowed  by  a  copious  watery  discharge  from 
the  nose.  After  this  he  falls  asleep,  to 
be  awakened  in  a  short  while  by  another 
attack  of  asthma,  which  is  in  turn  re- 
lieved by  sternutation.  He  sleeps  ha- 
bitually on  his  right  side,  with  the  head 
elevated.  This  state  of  affairs  lasts 
from  the  second  week  in  August  to  late 
in  September,  when  the  coryza  and  asth- 
ma disappear,  leaving  him  m  a  state  of 
nervous  prostration  and  with  a  slight 
nasal  discharge.  During  the  period  of 
"  cold  "  the  apex  and  sides  of  the  nose 
frequently  become  excessively  vascular, 
and  the  skin  is  cast  off  as  die  disease 
subsides.  During  the  past  four  years, 
the  paroxysms  have  been  increasing  in 
severity,  the  present  attack  having  com- 
pelled him  to  give  up  his  position  as  a  waiter  in  one  of  the 
hotels  of  the  city.  The  disease  may  come  on  at  any  season 
of  the  year,  if  he  is  exposed  to  its  exciting  causes,  but  he 
rarely  suffers  between  April  ist  and  the  second  week  in 
August.  At  the  latter  period  he  never  escapes.  Among 
the  exciting  causes  in  his  case,  apart  from  the  emanations 
from  hay,  are  exposure  to  sudden  atmospheric  changes, 
coal  dust,  the  use  of  tobacco,  the  inhalation  of  tobacco 
smoke,  and  the  greasy  smell  of  the  kitchen.  The  dust 
from  cleaning  various  articles,  dusting  carpets,  door-mats, 
etc.,  invariably  provokes  coryza.  The  odor  or  presence 
of  flowers,  light,  and  diet  have  no  effect  at  any  season  of 
the  year.  He  has  never  had  any  symptoms  referable  to 
a  disordered  nervous  system  before  the  appearance  of  the 
asthmatic  feature  of  his  disease.  Since  then  has  become 
restless  and  irritable  and  is  subject  to  attacks  of  nervous 
debility. 

The  only  relief  he  has  ever  gotten,  apart  from  the 
natural  termination  of  the  paroxysm  by  sternutation,  has 
been  from  the  inhalation  through  the  nostrils  of  the 
fumes  of  some  proprietary  pastils. 

Physical  examination, — No  disease  of  lower  respiratory 
apparatus.  Simple  congestion  of  nasal  and  lower  phar- 
ynx. Posterior  extremities  of  the  lower  turbinated 
bones  engorged,  swollen,  bright  red,  and  covered  with  a 
translucent  film  of  mucus.  Posterior  nares  symmetrical. 
Hypertrophic  enlargement  of  the  erectile  tissue  of  the 
posterior  part  of  septum  on  right  side.  Anterior  extremi- 
ties of  inferior  turbinated  bodies  slightly  swollen,  bright 
red,  and  present  the  appearance  of  two  little  rounded 
prominences  jutting  out  from  the  outer  half  of  the  nasal 
floor.  The  interval  between  them  and  the  middle  is 
considerable,  and  the  latter  are  remarkably  prominent, 
running  in  an  oblique  direction  from  behind,  upward 
and  forward.  Septum  straight,  face  S3rmmetrical.  The 
mucous  membrane  covering  the  anterior  end  of  the 
middle  turbinated  body  especially  swollen,  but  the  swell- 
ing can  be  readily  reduced  with  the  probe,  the  action 
awakening  no  reflex. 

Systematic  exploration  of  all  accessible  portions  of 
the  nasal  chambers  with  the  probe  gave  rise  to  no  re- 
flex except  at  one  spot.  Along  the  inner  edge  of  the 
left  inferior  turbinated  body,  about  one  and  one-fourth 


428 


THE  MEDICAL  RECORD. 


[October  i8,  1884. 


inch  by  measurement  within  the  nostril,  the  most  ex- 
quisite paroxysm  of  ctsthma  followed  the  simple  contact 
of  the  exploring  probe.  The  sonorous  and  sibilant  rilles 
were  loud  enough  to  be  heard  in  the  adjoining  room. 
The  conjunctivae  became  flushed,  painful,  and  covered 
with  tears,  and  a  thin  watery  discharge  accumulated  in 
the  nostrils.  These  symptoms  lasted  for  a  few  moments 
and  passed  away,  leaving  the  condition  as  described 
above.* 

My  views  in  regard  to  the  predisposing  and  exciting 
causes  of  the  disease  popularly  known  as  *'  hay  asthma," 
have  been  given  in  a  condensed  form  elsewhere,'  and 
the  design  of  the  present  article  is  to  supplement  these 
by  calling  attention  to  some  additional  facts  derived 
from  personal  study  of  the  affection. 

While  the  majority  of  cases  that  apply  for  treatment 
come  from  the  educated  classes,  and  from  those  of  fair 
intellectual  development,  it  must  not  be  forgotten  that  it 
is  precisely  this  class  that  seek  intelligent  medical  ad- 
vice, or  are  likely  to  come  within  the  range  of  circulars 
distributed  by  those  investigating  the  complaint.  Look- 
ing upon  the  disease  as,  to  all  intents  and  purposes,  a 
coryza,  generally  dependent  upon  abnormal  excitabilitv 
of  the  vaso-motor  centres,  it  does  not  seem  to  me  justi- 
fiable to  confine  the  operation  of  its  causes  within  the 
limits  of  a  particular  century,  or  to  explain  its  phenomena 
on  the  hypothesis  of  national  or  race  peculiarities.  I 
meet  with  it  at  all  ages  and  in  every  condition  of  life,  in 
private  and  in  hospital  practice.  I  find  it  more  com- 
mon among  women  than  is  generally  supposed,  and  am 
inclined  to  think  that  the  question  of  sex  is  one  of  un- 
important etiological  significance.  1  have  twice  observed 
the  disease  in  several  members  of  the  same  family,  and  it 
is  possible  that  a  peculiar  excitability  or  deranged  condi- 
tion of  the  vaso-motor  system  may  descend  from  father 
to  son,  and  detennine  the  appearance  of  the  affection  in 
the  latter ;  bu:  it  is  difficult  to  say  how  far  the  influence 
of  inheritance,  as  originally  suggested  by  Wyman,  enters 
as  a  factor  into  its  causation. 

In  the  majority  of  cases  that  have  come  directly  or  in- 
directly under  my  observation,  the  paroxysms  are  induced 
by  a  variety  of  agencies  differing  entirely  in  their  character 
and  mode  of  operation.  In  others  there  is  apparently 
only  one  exciting  cause.  The  latter  may  be  in  operation 
only  during  certain  periods  of  the  year,  or  may  provoke 
an  attack,  without  regard  to  season,  whenever  applied. 

It  may  be  said,  in  general,  that  the  exciting  cause  may 
produce  its  effect,  (i)  by  direct  or  indirect  (reflex)  irrita- 
tion of  the  sensitive  nerves  of  the  nasal  mucous  mem- 
brane; (2)  through  olfactory  impression  (so-called 
•* idiosyncrasy "  of  olfaction);  or  (3)  through  simple 
association  of  ideas  ;  or  the  same  result  may  be  brought 
about  (4)  by  ph3fsical  or  mental  overexertion,  or  (5) 
emotional  excitement. 

Typical  paroxysms  occur  in  some  persons  at  any  sea- 
son of  the  year,  from  sudden  changes  in  the  temperature 
or  from  electrical  disturbance  of  the  atmosphere,  and  so 
far  as  my  observation  goes,  a  prominent  position  should 
be  accorded  to  meteorological  conditions  among  the  ex- 
citing causes. 

Pollen  is  only  one  of  a  host  of  exciting  causes,  and 
there  is  reason  to  believe  that  in  some  cases  in  which  it 
is  supposed  to  be  the  excitant,  it  has  little  or  no  influence 
at  all.  The  paroxysm  may  be  produced  as  a  reflex 
phenomenon  from  irritation  of  a  distant  organ,'  and  a  case 
has  been  brought  to  my  notice  by  a  distinguished  medical 
friend,  in  which  the  ingestion  of  a  few  grains  of  quinia  is 
sufficient  to  produce  a  group  of  symptoms  which,  if  they 
were  excited  by  smelling  a  rose,  would  be  called  "  rose 

>  The  Mnsitive  tpot  was  destroyed  by  a  stellate  incision  with  the  small  knife  of 
the  galrano^autery.  On  the  night  of  the  operatiOD  the  patient  had  a  slight  attadc 
of  asthma,  which  passed  off,  however*  in  the  course  of  an  hour.  For  the  next  five 
days  he  enjoyed  perfect  immunity  from  the  disease.  He  then  went  on  a  fiiiting 
expeditioa  with  a  oarty  of  gentlemen,  and  the  first  night  out  contracted  a  violent 
cold  in  the  head  trom  sleeping  on  the  damp  ji^und,  and  with  the  corysa  the  at- 
tacks of  asthma  returned.  At  the  present  writing  treatment  has  been  suspended 
until  the  attack  of  cor>'a  subsides. 
.   *  This  journal,  July  19,  1884.  *  See  paper  referred  to  above. 


cold."  More  accurate  observations  are  necessary  to  the 
formulation  of  definite  conclusions  concerning  the  oc- 
currence of  this  disease  in  the  inferior  races.  While  it  is 
doubtless  true,  that  the  physical  and  moral  forces  of 
civilization  encourage  its  development  in  the  higher 
walks  of  life,  they  probably  do  so  only  in  so  far  as  they 
predispose  to  abnormal  excitability  of  the  nervous  system 
in  general,  or  to  catarrhal  and  asthmatic  afiections. 

In  the  black  race,  the  exquisite  delicacy  of  the  sense 
of  smell,  the  prominent  development  of  the  turbinated 
bones,  and  the  consequent  increased  amount  of  surface 
exposed,  would  seem  to  invite  the  paroxysm  in  those 
surrounded  by  the  conditions  that  provoke  it.  I  have 
several  times  met  with  reflected  phenomena  in  the  negro 
referable  to  disease  of  the  nose,  and  belonging  to  the 
same  category  of  reflex  affections ;  and  it  is  possible  that 
a  fair  proportion  of  cases  of  the  convulsive  asthma  which 
occur  in  that  race  may  have  a  similar  origin. 

While  the  above  case  is  the  only  instance  of  the  oc- 
currence of  the  disease  in  the  negro  that  has  come  under 
my  personal  observation,  it  is  quite  possible  that,  if  looked 
for,  it  may  be  more  frequently  found. 


DANGER  FROM  PLASTER-OF-PARIS  JACKETS. 

Wfth  a  Description  of  the  Woven-wire  Jacket. 

By  SAMUEL  W.  SMITH.  M.D., 

NBW  YORK  CITY. 

In  the  science  of  medicine,  as  in  other  sciences,  there  is 
a  tendency  to  follow  certain  recognized  plans  or  systems 
of  procedure,  to  the  ignoring;  of  original  methods,  and  a 
tendency  to  forget  that  while  all  may  have  advantages, 
and  promise  good,  all  must  have  in  some  case  disadvan- 
tages that  tend  to  evil.  This  fact  has  been  forcibly  iin- 
pressed  upon  my  mind  in  the  use  of  the  plaster-of-Paris 
jacket  in  cases  of  Potf  s  disease  of  the  spine. 
The  following  cases  will  illustrate  my  meaning : 

Case  I. — Daisie  D ,  aged  seven.    Born  of  healthy 

parents,  her  own  health  was  good  until  she  reached  her 
fifth  year,  when  it  was  observed  that  she  constantly  rested 
her  head  upon  her  hands  when  not  at  play.  She  soon 
became  very  irritable,  and  refused  to  play  with  other 
children.  At  this  time  she  was  taken  to  the  family  phy- 
sician who  discovered  an  angular  curvature  of  the  spine, 
including  the  last  cervical  and  first  and  second  dorsal 
vertebrae.  In  the  course  of  time  a  Tiemann  &  Co.'s  splint 
with  jury-mast  was  put  on.  The  child  did  well  and  re- 
turned to  its  amusements  as  usual.  Within  about  a  year 
the  child  had  grown  so  much  that  the  splint  could  not  be 
worn  without  a  slight  change  being  made  in  it.  At  this 
time  the  patient  came  under  my  care  for  a  bronchial  af- 
fection, which  disappeared  after  appropriate  treatment  of 
two  or  three  weeks'  duration.  In  accordance  with  the 
advice  of  friends  she  was  taken  by  the  parents  to  a  sur- 
geon of  this  city,  by  whom  a  plaster-of-Paris  jacket  was 
substituted  for  the  Tiemann  &  Co.'s  splint.  For  a  day  or 
two  the  child  appeared  to  be  quite  as  comfortable  as  with 
the  former  apparatus,  but  within  a  week  I  was  again 
called  to  see  her.  I  found  her  suffering  from  capillary 
bronchitis.  The  attendance  of  the  surgeon  who  had  pot 
on  the  plaster  jacket  was  requested  by  me,  and  he  at 
once  removed  it  On  the  third  day  the  little  patient  died 
of  capillary  bronchitis.  My  own  opinion  is,  that  the  pri- 
mary cause  of  death  in  this  case  was  due  to  the  sudden 
cooling  of  the  body  of  the  child  which  was  effected  by  the 
hardening  and  drying  process  of  the  plaster  composing 
the  jacket. 

Case  II. — Nellie  R ,  fourteen  years  of  age,  fifom 

Connecticut  Came  to  the  Demilt  Dispensary  in  the 
spring  of  1 88 1,  suffering  from  lateral  curvature  of  the 
spine.  Bom  of  healthy  parents ;  her  own  general  bealdi 
good  ;  no  bronchial  disease.  I  put  on  a  plaster-of-Paris 
jacket  and  ordered  daily  exercise  with  the  pulley  and 
chin  support.     In  three  weeks  she  returned  to  my  office 


October  i8,  1884.] 


THE   MEDICAL  RECORD. 


429 


suffering  from  a  severe  bronchitis,  loss  of  appetite,  and 
irritable  cough.  I  removed  the  jacket,  and  in  a  few 
weeks  the  patient  returned  entirely  recovered  from  the 
bronchial  difficulty.  I  then  applied  a  second  jacket,  do- 
ing so  at  my  office,  where  die  room  was  properly  warmed 
to  prevent  the  likelihood  of  "  catching  cold."  In  two 
months  she  returned  and  informed  me  that  during  all 
this  time  she  had  suffered  from  a  troublesome  cough ; 
but  so  anxious  was  she  to  get  rid  of  her  deformity,  that 
she  had  preferred  to  endure  the  cough  rather  than  have 
the  jacket  removed !  However,  I  removed  it,  and  or- 
dered a  corset,  made  over  a  slight  untempered  steel 
frame,  and  covered  with  firm  material,  something  after 
the  plan  of  Professor  L.  A.  Sayre's  spinal  wire  cor- 
set. The  corset  was  easily  made  by  taking  the  removed 
plaster  jacket  and  filling  it  with  plaster  prepared  for  the 
purpose.  This  gave  me  a  complete  cast  of  the  deform- 
ity. The  suspension  treatment 
was  still  continued,  and  with  the 
greater  ease  and  comfort  of  the 
corset,  my  patient  steadily  im- 
proved. The  bronchitis  and 
cough  disappeared  in  a  short 
time. 

During  my  service  at  the  De- 
milt  Dispensary  several  other  pa- 
tients to  whom  I  had  applied  the 
plaster  jacket  gave  me  the  same 
kind  of  trouble  ;  so  that  about 
two  years  ago  I  abandoned  the 
use  of  it,  excepting  in  such  cases 
of  Dispensary  patients  as  were 
unable,  through  poverty,  to  pay 
for  the  corset  In  all  cases  in 
which  I  was  thus  obliged  to  use 
the  plaster  jacket,  I  opened  the 
front  and  so  arranged  it  that  re- 
moval at  bedtime  could  be  easily 
accomplished,  as  also  the  replac- 
ing of  it  before  arising. 

The  corset  which  I.have  used 
instead  of  the  plaster-of-Paris 
jacket  can  be  made  of  any  strong,  pliable  material,  over 
the  untempered  steel  frame  ;  but  that  which  I  have 
more  recently  had  made  is  of  light  tinned  wire,  interwo- 
ven in  the  iron  frame,  and  shaped  over  the  plaster  cast 
of  the  deformed  patient.  Professor  F.  H.  Hamilton's 
"  Wire  Gauze,Hip  Splint  "  suggested  to  me  the  use  of  the 
same  material  -for  my  corset.  It  is  easily  arranged  for 
the  use  of  the  jury-mast  when  needed,  by  means  of  screw 
loops  on  the  two  steel  rods  which  give  support  to  the 
back.  The  legs  of  the  jurj-mast  having  slits  in  them  can 
easily  be  made  fast  by  a  screw. 

In  addition  to  the  disadvantages  of  wearing  a  plaster- 
of-Paris  jacket  for  consecutive  months,  alluded  to  above, 
it  seems  but  reasonable  to  suppose  that  by  this  long-con- 
tinued pressure  of  the  chest  walls,  their  natural  growth 
should  be  stunted,  their  capacity  for  lung  expansion  much 
lessened,  and  a  road  laid  out  which  may  lead  on  to 
phthisis. 

40  Wbst  Twenty-fii-tii  Strkkt, 


Back  View"of  Corset. ; 


Treating  Tape-Worm  with  Chloroform. — Dr.  I.. 
E.  Borcheim,  of  Atlanta,  Ga.,  writes  that  he  has  treated 
two  patients  suffering  from  taenia  solium,  with  chloro- 
form, etc.,  according  to  the  method  of  Dr.  J.  G.  Brooks 
(Medical  Record,  Vol.  26,  Nos.  4  and  11).  In  both 
cases  he  was  unsuccessful.  The  patients  complained  of 
feelings  of  intoxication,  the  pulse  rose,  purging  was  brisk, 
but  no  tape-worm.  On  the  other  hand.  Dr.  N.  S.  Dar- 
ling, of  La  Forte,  Ind.,  states  that  he  administerec^  after 
a  Oast  of  twenty-four  hours,  chloroform  3  j.,  with  castor- 
oil  5  iJ->  to  an  adult  male,  with  the  result  of  expelling  a 
tape-worm  thirty-seven  feet  in  length.  The  head,  it  is 
believed,  was  brought  away  with  the  mass. 


A  CURIOUS  INJURY  FROM  A  PITCHFORK. 
By  a.  A.  ELLIOTT,  M.D., 

STEUBBNVILLB,   O. 

On  August  19th  I  saw,  in  consultation  with  Drs.  G.  A. 
Shane  and  J.  F.  Whittaker,  the  following  case  : 

William  P ,  a  farmer,  thirty  years  of  age,  weighing 

about  one  hundred  and  fifty  pounds,  muscular  develop- 
ment good,  while  sliding  from  a  hay- mow  came  in  con- 
tact with  a  pitchfork  which  was  standing  tines  upward 
against  the  contents  of  the  mow.  One  of  the  prongs 
penetrated  the  right  hip,  at  a  point  behind  and  on  a  level 
with  the  greater  trochanter,  and  broke  off  close  to  tjie 
socket. 

Found  him  lying  on  the  porch  of  the  house,  to  which 
he  had  been  taken,  complaining  of  severe  pain  in  his  hip, 
abdomen,  and  back,  and  greatly  frightened.  On  exami- 
nation we  found  a  penetrating  wound  in  the  right  hip, 
and  just  beneath  the  surface  a  metallic  substance  was 
detected  and  removed,  being  the  lower  portion  of  the 
fork-tine,  one  and  three-quarter  inch  in  length,  and  fit- 
ting accurately  at  its  larger  end,  the  stump  remaining  on 
the  handle.  Measurement  of  the  remaining  tine  showed 
it  to  be  thirteen  inches  in  length,  leaving  about  eleven 
inches  yet  to  be  accounted  for. 

The  patient  complained  greatly  of  his  back,  and  a  view 
of  it  disclosed  an  enlargement  on  the  right  side  of  the 
spinal  column  in  the  lumbar  region,  which  was  exquisitely 
sensitive.  This  apparent  swelling  showed  no  bruising  or 
evidence  of  recent  contusion,  and  inquiry  elicited  no 
history  of  its  existence  previous  to  this  time. 

We  proceeded,  under  an  anaesthetic,  to  further  explore 
for  the  missing  steel,  and  found  the  direction  of  the  wound 
to  be  upward,  inward,  and  forward,  and  succeeded  in  fol- 
lowing its  track  for  about  five  inches  with  a  probe,  but 
without  detecting  any  foreign  body,  nor  could  we  by  en- 
larging the  wound  and  making  deep  pressure  determine  , 
its  presence. 

He  was  allowed  to  come  out  from  under  the  influence 
of  the  ether  in  order  to  get  the  benefit  of  his  sensations 
under  our  manipulations,  and  his  thigh  was  flexed  on  his 
abdomen,  deep  pressure  again  made,  together  with  ab- 
duction and  adduction  of  the  thigh,  producing  no  increase 
of  pain  in  any  region. 

After  several  hours  he  was  again  etherized,  and  the 
most  critical  examination  made  in  the  wound  and  by  the 
rectum,  and  the  swelling  on  the  back  laid  open  and 
thoroughly  explored  ;  all  to  no  purpose,  and  the  wounds 
were  left  unclosed  and  dressed  with  water  dressing. 

The  case  resolved  itself  into  the  following  conditions  : 
I.  Head  of  the  fork-tine  penetrated  and  lodged  in  the 
body  of  the  man ;  if  so,  could  it  be  removed  ?  2.  If  in 
his  body,  had  it  penetrated  the  pelvic  cavity  or  was  it 
buried  in  the  dense  muscular  structure  of  the  hip  ?  3. 
Could  it  be  possible  that  the  first  portion  of  the  tine  had, 
by  the  force  of  the  falling  body,  broken  off  and  by  its 
elasticity  flew  away,  and,  the  fall  being  unbroken,  the 
fork  again  came  in  contact  with  the  body  and  penetrated 
with  the  remainder?  These  questions  were  taken  up 
and  concluded  upon :  i.  There  was  no  positive  evidence 
furnished  by  the  examination  that  the  tine  was  lodged  in 
his  body,  and,  were  it  positive,  an  operation  for  its  re- 
moval would  involve  a  dissection  of  the  muscular  struct- 
ure of  the  hip,  and  perhaps  an  opening  of  the  abdominal 
cavity,  both  under  the  circumstances  unjustifiable  opera- 
tions. 2.  The  abdominal  pain  was  taken  as  suspicious 
at  least,  and  the  bladder  and  rectum  had  not  as  yet  acted, 
leaving  their  injury  in  doubt.  3.  The  possibility  of  this 
condition  was  acted  upon,  and  the  bam  most  thoroughly 
searched  for  the  missing  tine,  but  it  was  not  found. 

We  now  concluded  to  leave  the  case  to  nature,  and 
the  patient  went  on  doing  well,  his  bowels  and  bladder 
performing  their  functions  normally.  After  a  few  days, 
when  his  fright  had  subsided,  he  remembered  that  the  in- 
jury to  his  back  was  of  lon^  ago,  and  always  gave  him 
trouble,  and  that  his  abdommal  pain  had  preceded  the 


430 


THE   MEDICAL   RECORD. 


'  [October  18^  1848. 


injory  several  days  and  had  been  accompanied  with  diar- 
rhoea, which  continued.  The  wound  in  the  back  healed 
kindly,  but  the  one  in  the  hip  continued  to  discharge 
profusely,  and  in  the  fourth  week  the  whole  limb  became 
swollen,  and  later  fluctuation  was  detected  below  the 
sore,  which  increased  in  size  and  extended  down  the  pos- 
terior aspect  of  the  thi^h^  and  on  October  ist,  forty- 
three  days  after  the  accident,  it  (the  tine)  was  removed, 
large  end  first,  from  the  upper  portion  of  the  popliteal 
,  space.     It  was  eleven  inches  in  length. 

The  tine  was  evidently  lodged  either  in  the  hip  or  had 
penetrated  the  pelvis,  the  heavy  end  being  depend- 
ent, and  the  muscular  action  produced  by  the  patient's 
walking  across  the  floor  daily  caused  it  to  descend  and 
appear  as  described. 

Since  its  removal  he  is  doing  well,  and  the  indications 
are  that  he  will  make  a  good  recovery. 

SOME  REMARKS   ON  THE   ASSOCIATION   OF 
i.  TUBERCULOSIS  AND  ACUTE  PNEUMONIA. 
By  EDMUND  C.    WENDT,  M.D., 

CURATOR  TO  ST.   FRANCIS   HOSPITAL,    NEW  YORK. 

The  highly  interesting  case  of  tuberculous  pneumonia, 
reported  by  Dr.  Kinnicutt  in  the  last  issue  of  The  Rec- 
6rd^  prompts  the  writer  to  offer  a  few  remarks  on  the 
sjmchronous  occurrence  of  tuberculosis  and  pneumonia, 
particularly  so  as  a  case  came  under  his  observation  four 
years  ago,  which  was,  in  some  respects  at  least,  similar 
to  the  one  observed  by  Dr.  Kinnicutt.  The  writer  con- 
sidered it  at  the  time  a  rather  puzzling  instance  of  rapidly 
fatal  croupous  pneumonia,  of  an  atypical  kind.  Having 
occurred  before  the  era  of  the  bacillus  tuberculosis  and 
the  pneumonia-micrococcus,  it  will  scarcely  seem,  in  the 
light  of  our  present  knowledge,  or  at  least  widespread 
belief,  a  case  observed  with  sufficient  scientific  accuracy 
to  warrant  any  concise  deductions.  But  it  should  not  be 
foiFgotten  that,  despite  the  rapidly  progressive  researches 
of  positive  experimental  pathology,  the  entire  subject  of 
pneumonia,  and  for  that  matter  of  tuberculosis  as  well,  is 
still  a  debatable  one. 

The  writer's  case,  then,  is  to  be  regarded  merely  as  a 
casuistical  contribution  to  a  subject  of  universal  interest 
to  the  profession  in  the  past,  the  present,  and,  it  is  to  be 
hoped,  the  future. 

Quite  briefly  stated  the  case  was  as  follows  :  A.  M , 

male,  aged  tliirty-six,  married,  the  father  of  healthy 
children,  himself  the  chDd  of  healthy  parents,  was  seized 
with  a  rigor  on  a  Monday,  in  March,  1880.  He  posi- 
tively denied  any  previous  serious  illness,  but  admitted  a 
tendency  to  "  take  cold "  easily  during  changeable 
weather.  He  also  stated  that  he  had  lost  one  sister 
from  phthisis,  at  the  age  of  twenty-two.  Soon  after  the 
chill  the  patient  developed  the  signs  of  croupous  pneu- 
monia on  the  right  side,  which  soon  spread  throughout 
the  entire  middle  and  lower  lobes.  It  was  thought  to 
be  even  encroaching  on  the  upper  lobe,  when,  on  the 
third  day,  after  the  rigor  had  marked  the  incipience  of 
severe  illness,  he  suddenly  died.  Clinically  the  unusual 
signs  had  been  an  excessively  high  temperature  (io6f° 
to  107°  F.,  in  the  rectum),  associated  with  a  pronounced 
typhoid  condition.  On  the  last  day  of  his  illness  the 
patient  also  became  intensely  jaundiced. 

At  the  autopsy  the  right  lung  was  found  hepatized  in 
the  middle  and  lower  lobes.  The  hepatization,  however, 
was  grayish  only  in  a  few  places,  the  prevailing  color 
being  a  dark  maroon.  In  the  upper  lobe,  there  was 
merely  moderate  congestion,  some  firm  old  pleuritic  ad- 
hesions, a  few  slate-colored  nodules  with  chalky  centres, 
and  a  rather  abundant  crop  of  miliary  tubercles.  Besides 
this  there  were  in  both  lungs  quite  a  number  of  purulent  foci, 
resembling  the  well-known  multiple  abscesses  of  pyaemia. 

The  left  lung  was  congested,  oedematous,  and  showed 
in  its  upper  lobe  a  condition  quite  similar  to  what  ob- 
tained on  the  right  side,  ^except  that  there  were  relatively 
fewer  miliary  tubercles  and  purulent  collections.  The 
latter  in  no  instance  exceeded  in  size  that  of  a  cherry-pit. 


The  abdominal  organs  were  in  general  much  cbngested, 
especially  the  spleen,  which  was  soft,  large,  and  pulpy. 
The  liver  was  found  in  the  first  stage  of  icteric  hepatitis. 
The  intestines  were  only  moderately  hyperamic,  other- 
wise noritoal.  The  common  bile-duct  was  easily  per- 
vious. The  brain  was  not  examined.  There  were  no 
miliary  tubercles  in  any  other  organs,  save  those  already 
mentioned,  viz.,  the  upper  lobes  of  both  lungs. 

The  questions  that  suggest  themselves  in  this  case,  as 
well  as  in  the  one  reported  by  Dr.  Kinnicutt,  are  these : 
Was  there  a  latent  unrecognized  tuberculosis  upon  which, 
as  a  suitable  soil,  a  fatal  croupous  pneumonia  became 
engrafted?  or  was  there  rather  a  primary  lobar  pneu- 
monia, that  afforded  a  fertile  soil  for  the  rapid  develop- 
ment of  acute  tuberculosis  ?  Without  stopping  to  weigh 
arguments  pro  and  contra,  the  writer  would  simply  stale 
his  belief  that  in  his  own  case  the  tuberculosis  preceded, 
for  weeks  or  months,  the  pneumonia ;  but  that  the  latter 
would  not  have  proved  so  rapidly  fatal  without  the  coexist- 
ence of  the  former.  In  Dr.  Kinnicutt's  case  the  se- 
quence of  events  seems  less  clear.  And  it  is  much  to  be 
regretted  that  the  microscopical  examination  of  the  spu- 
tum failed  to  make  matters  any  clearer. 

One  thing  may  be  learned  from  these  cases.  If  croup- 
ous pneumonia  is  an  infectious  disease,  caused  by  the  in- 
vasion of  a  specific  micro-organism,  and  if  pulmonary 
tuberculosis  similarly  depends  upon  the  entrance  into  the 
lungs  of  peculiar  bacilli,  then  it  follows  that  the  growth 
and  multiplication  of  these  two  typical  and  vastly  dis- 
similar varieties  of  germs  within  the  same  organ,  so  far 
from  being  mutually  antagonistic,  may  be  reciprocally 
stimulating,  and  thus  prove  doubly  dangerous  to  the  host 
carrying  the  parasites. 

In  conclusion,  the  writer  may  be  permitted  to  suc< 
cinctly  refer  to  a  case  of  so-called  *' mixed  infection 
through  tubercular  bacilli  and  pneumonia-micrococci," 
which  was  recently  reported  by  Dr.  Samter  (Berliner 
Klin,  Wochenschrift,  June  23,  1884),  and  which  seems 
to  have  escaped  Dr.  Kinnicutt's  notice. 

A  weak  and  marantic-looking  old  man,  aged  sixty-five, 
was  admitted  to  the  Posen  hospit^  on  March  13,  1884. 
The  patient  had  a  slight,  innocent-seeming  cough,  and 
a  physical  examination  led  only  to  the  diagnosis  of  senile 
bronchitis.  The  patient  improved  visibly  at  first  But 
on  April  19th  he  began  to  complain  of  great  weakness, 
and  showed  an  increased  tendency  to  cough.  His  tem- 
perature, however,  was  below  the  normal.  The  scanty 
viscid  sputum  resembled  somewhat  that  of  ordinary  lobar 
pneumonia.  Microscopical  examination,  however,  elic- 
ited the  interesting  fact  that,  in  addition  to  the  abundant 
presence  of  tubercle  bacilli,  the  sputum  contained  a  few 
of  the  characteristic  micrococci  of  pneumonia.  The 
physical  signs  of  the  latter  affection  subsequently  became 
more  marked,  and  the  patient  died  in  a  few  days  from 
heart-failure.  From  the  record  of  the  post-mortem  ex- 
amination the  following  points,  having  a  direct  bearing 
on  the  subject  under  discussion,  may  be  cited :  In  the 
apex  of  the  left  lung  there  were  some  old  cheesy  de- 
posits, the  entire  right  lung  was  intensely  congested  and 
in  the  first  stage  of^neumonia. 

Scattered  throughout  all  the  lobes  of  this  lung  there 
was  found  an  abundant  crop  of  recent  miliary  tubercles, 
but  not  a  single  cheesy  or  purulent  mass  was  discover- 
able in  that  lung.  In  the  small  intestine  numerous  ul- 
cers existed,  but  there  was  no  evidence  there  of  miliaiy 
tuberculosis.  It  would  seem,  therefore,  that  this  case 
resembled  my  own  in  several  important  respects.  Dr. 
Samter  is  inclined  to  believe  that  his  patient  had  latent 
tuberculosis ;  and  further,  that  a  sudden  invasion  of  the 
specific  germs  of  pneumonia  wrought  such  changes  in  al- 
ready damaged  lungs  that,  an  acute  miliary  tuberculosis 
was  lit  up  where  before  there  had  only  existed  the  slowly 
smouldering  process  of  chronic  tuberculosis. 

In  the  light  of  the  experience  of  his  own  case,  the 
writer  would  fully  concur  in  the  above  opinion. 

10a  East  Fifty-skventh  Stkbbt,  October  14,  1884. 


<v:;:»r :  • /•  •  i-'; ' 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


431 


fr00r«B«  at  P^jetf ijcal  ^jcience. 

Adynamic  Dilatation  of  the  Stomach. — Dr.  Enrique 
de  Argaez  has  lately  published  a  niODOgraph  on  the  above 
subject  (Paris:  Asselin  &  Co.,  1884),  which  embodies  a 
few  novel  points  touching  the  pathogenesis  and  treat- 
ment of  this  interesting  disease.  In  typical  cases  the 
author  has  usually  found,  on  inspection,  abnormal  prom- 
inence of  the  epigastrium,  and,  more  rarely,  visible 
peristaltic  movements  of  the  stomach.  The  varying 
quality  of  resonance  obtained  by  percussion  over  the 
colon,  the  small  intestine,  and  the  stomach,  enables  the 
observer  to  define  the  boundaries  of  the  dilated  organ. 
Succussion  yields  a  characteristic  sound,  due  to  the  simul- 
taneous presence  of  g;as  and  liquid  in  the  stomach,  and 
sometimes  a  metallic  tinkling.  M.  G^main  S^e,  in  whose 
service,  at  the  H6telDieu,  most  of  the  cases  observed 
by  Dr.  de  Argaez  were  observed,  finds  proof  of  the  ex- 
istence of  adynamic  dilatation  in  the  presence  of  gastric 
resonance  at  a  distance  greater  than  twelve  or  fifteen 
centimetres  beyond  the  left  mamillary  line,  or  the  pres- 
ence of  the  gastric  succussion  sound  six  hours  after  eat- 
ing. Under  the  head  of  symptomatology  the  familiar 
phenomena  of  epigastric  pain,  flatulence,  emesis,  and 
constipation  are  described.  The  principal  causes  of  the 
dilatation  are  general  weakness,  disturbed  local  innerva- 
tion, and  excessive  ingestion  of  aliment.  The  differential 
diagnosis  involves  the  exclusion  of  gastralgia  in  ataxic 
patients,  whose  stomachs  are  not,  however,  found  dilated, 
and  of  gastric  ulcer.  In  the  latter  disease,  blood,  either 
pure  or  partially  digested,  and  presenting  the  familiar 
coffee-ground  aspect,  is  often  present.  This  feature  is  al- 
ways absent  in  atonic  gastric  dilatation.  Other  diseases 
to  be  excluded  are  alcoholic  gastritis,  fibrous  stenosis  of 
the  pylorus,  and  carcinoma.  In  pyloric  stenosis,  whether 
of  a  benign  or  of  a  malignant  character,  the  entire  con- 
tents of  the  stomach  are  rejected  by  vomiting,  which  is 
not  the  case  in  adynamic  dilatation.  Under  the  head  of 
treatment  the  author  suggests  a  diet  calculated  to  leave 
no  undigested  residue  in  the  stomach,  such  as  eggs,  and 
tender  meats,  moderate  exercise,  gentle  laxatives,  and 
the  use  of  Kussmaul's  pump  and  Fancher's  siphon- tube, 
to  evacuate  the  distended  stomach.  The  gastric  pain  is 
best  relieved  by  chloroform,  administered  in  small  doses 
by  the  mouth,  and  by  the  continuous  galvanic  current. 
The  author  is  in  the  habit  of  placing  the  positive  pole  at 
the  centre  of  the  epigastrium,  and  the  negative  over  the 
sternum.  The  current  is  allowed  to  pass  ten  or  twelve 
minutes  at  each  sitting. 

Why  Negroes  are  Black. — Surgeon-Major  Alcock 
has  contributed  to  Nature  a  communication  on  the  reason 
why  tropical  man  is  black,  in  which  he  suggests  that,  as 
in  the  lowest  animals  pigment-cells  placed  behind  a  trans- 
parent nerve-termination  exalt  its  vibration  to  the  highest 
pitch,  the  reverse  takes  place  when,  as  in  the  negro,  the 
pigment-cells  are  placed  in  front  of  the  nerve-termina- 
tions, and  that  the  black  pigment  in  the  skin  serves  to 
lessen  the  intensity  of  the  nerve-vibrations  that  would  be 
caused  in  a  naked  human  body  by  exposure  to  a  tropical 
sun.  In  fact,  he  thinks  that  the  pigment  plays  about  the 
same  part  as  a  piece  of  smoked  glass  held  between  the  sun 
and  the  eye. 

The  Treatment  of  Psoriasis. — In  the  treatment  of 
psoriasis,  Professor  Neumann,  of  Vienna,  recommends 
arsenic  in  the  form  of  the  so-called  *' Asiatic  pills,"  which 
are  composed  thus  :  Arsenious  acid,  gramme  i.o  ;  black 
pepper,  grammes  5.0;  acacia  gum,  gramme  1.5;  with  a 
sufficiency  of  distilled  water.  The  ingredients  must  be 
thoroughly  pulverized  and  mixed,  then  enough  gum  arabic 
must  be  added  to  make  two  hundred  pills.  Each  pill  con- 
tains 0.005  gramme  of  arsenic.  These  are  to  be  taken 
each  day  at  first,  and  gradually  increased  till  ten  or  twelve 
are  taken.  The  soft-soap  course,  as  an  external  remedy, 
in  the  form  of  the  **  Pfeuffer'schen  Cyclus,"  is  strongly 
recommended  in  cases^of  universal  psoriasis,  and  is  thus 


carried  out :  The  patient,  undressed,  is  )aid  between 
blankets  and  is  rubbed  twice  a  day  for  six  days,  and  once  ^ 
a  day  for  three  more  days,  with  the  ordinary  soft  soap^  one 
hundred  grammes  being  used  each  time.  The  rubbing  is 
conducted  in  such  a  manner  that  the  whole  of  the  affected 
skin  is  well  rubbed  each  time,  and,  at  each  application,  a 
fresh  portion  is  rubbed  in  with  a  hard  brush  in  such  a  man*- 
ner  that  the  surface  commences  to  bleed.  The  patient 
remains  in  woollen  cloths  night  and  day,  and  on  no  ac- 
count is  bathing  allowed  till  the  fourteenth  day,  and  the 
longer  this  is  delayed  the  more  easily  will  the  dried  skin 
and  soap  be  separated,  and  the  less  pain  and  sense  of. 
stretching  will  be  experienced.  In  case  the  bath  is  taken 
too  early,  the  skin  will  feel  too  short  and  tight,  movement 
will  be  difficult  or  impossible,  and  rhagades  are  very 
likely  to  occur. 

Essential  ANiEMiA. — Dr.  Rosenbach,  of  .  Breslan 
{Deutsche  Med,  Wochenschrift),  points  out  three  charac- 
teristics of  this  disease,  i.  It  recurs  at  certain  seasons 
of  the  year,  so  that  we  can  distinguish  a  spring,  a  summer, 
and  an  autumn  form.  Cases  occurring  in  winter  are  ex- 
tremely rare,  and  those  belonging  to  the  height  of  sum- 
mer seem  to  be  the  most  severe.  2.  A  peculiar  craving 
for  acids  is  displayed  by  the  patients,  which  must  not  be  , 
supposed  to  indicate  merely  a  deficiency  of  hydrochloric 
acid. in  digestion,  as  any  other  acid,  and  even  fresh  fruit, 
may  supply  the  want.  The  desire  for  acids  ought  to  be 
gratified,  as  it  is  the  assimilation  of  the  patient  that  is  at 
fault,  and  the  organism  instinctively  demands  what  is 
needed.  3.  Instead  of  feeling  strongest  in  the  mornings 
the  patients  are  at  their  best  in  the  late  afternoon  and 
evening,  or  sometimes  even  far  into  the  night  Their 
desire  for  food  follows  the  same  rule,  and  it  is  best  to  let 
them  eat  at  the  times  when  they  feel  most  appetite,  irre- 
spectively of  ordinary  meal  times.  It  is  also  of  no  use  to 
try  to  ensure  brightness  and  freshness  in  the  morning 
by  making  them  go  early  to  bed,  as  they  do  not  sleep 
until  their  time  of  feeUng  strong  has  passed  oS.  They 
ought  to  be  as  much  in  the  sun  and  fresh  air  as  possible, 
but  ought  not  to  fatigue  themselves  with  walking.  The 
anaemia  of  puberty  is  not  included  in  these  remarks.  Dr. 
Rosenbach  has  found  that  the  prognosis  of  the  cases  of 
essential  anaemia  is  more  favorable  when  the  weakness 
and  want  of  appetite  are  periodical,  than  when  the 
patients  are  always  tired,  and  refuse  all  kinds  of  food' 
alike. 

Medicinal  Treatment  of  Habitual  Constipation 
— Dr.  Mortimer  Granville,  in -the  British  Medical  Jour- . 
nal^  gives  three  prescriptions  for  habitual  constipation. 
Where  there  is  a  lax  and  torpid  condition  of  the  muscular 
coat  of  the  intestine,  the  following  is  recommended : 
3.  Sodas  valerianatis,  gr.  xxxvj.;  tinct.  nuc.  vpm.,  3j. ; 
tinct.  capsici,  TTlxlviij.;  syrupi  aurantii,  Sjss.  ;  aq.  ad 
3  vj.,  I  ss. ;  water  half  an  hour  before  meals.  Where 
there  is  a  deficiency  of  glandular  secretion  throughout 
the  intestine  the  following  is  useful :  ft.  Aluminis,  3  iij. ; 
tinct.  quassiae,  |j.;  infusi  quassias,  ad  |viij.  ;  f  j.  after 
meals.  A  third  form  of  ^constipation,  which  depends 
chiefly  on  interruption  of  the  natural  habit  of  periodic 
discharge,  is  benefited  by  directing  a  regular  attempt  to 
go  to  stool,  and  to  take  the  following  draught  the  first 
thing  after  rising  from  bed  :  Ammon.  carb.,  3  j. ;  tinct. 
Valerianae,  5J-;  aq.  camph.  ad  5  vj.  ;  take  a  sixth  part 
as  directed 

Generalized  Sarcoma  of  the  Skin  Cured  by  Sub- 
cutaneous Injections  of  Arsenic. — Generalized  sar- 
coma of  the  skin  occurs  very  rarely.  Professor  Kobner's 
patient  {Berliner  Klinische  lVochenschrift\  was  a  girl 
eight  ana  a  half  years  of  age.  The  tumors,  which  were 
exceedingly  numerous,  existed  over  the  whole  surface  of 
the  body,  except  the  nose  and  abdomen.  They  were 
bluish-red  in  color,  and  mostly  of  the  size  of  a  lentil  to  a 
split  pea.  They  were  hard  and  almost  painless  on 
pressure.  The  larger  ones  were  of  the  size  of  a  haricot 
bean.     The  lymphatic  glands  were  swollen,  and  the  liver 


432 


THE   MEDICAL   RECORD. 


[October  .18, 1884. 


and  spleen  were  slightly  enlarged.  There  was  no  fever^ 
but  a  feeble  appetite  and  generally  defective  nutrition. 
The  diagnosis  was  confirmed  by  an  examination  of  two 
tumors  which  were  e^tciscd  for  that  purpose.  The  treat- 
ment adopted  was  subcutaneous  injection  of  Fowler's 
solution  of  arsenic,  diluted  with  two  parts  of  disnlled 
water  to  one  of  the  solution.  A  dose  equivalent  to  two 
and  a  half  to  four  drops  of  Fowler's  solution  was  injected 
daily  ;  and  between  September  12  th  and  December  9thj 
eight  grammes  of  Fowler's  solution  had  been  injected*  It 
had  been  necessary  to  occasionally  suspend  the  injections, 
so  that  in  three  months  only  fifty  injections  had  been 
made.  From  December  i  oth  the  dose  of  Fowler's  solu- 
tion  was  raised  gradually  to  nine  drops  (diluted  always  in 
proportion).  The  result  of  the  arsenical  treatment  was 
ihe  gradual  dispersion  of  the  tumors^  and  the  diminution 
of  the  enlarged  lymphatic  glands.  Pigmented  spots  ex- 
isted for  some  time  over  the  seat  of  the  tumors,  and  in 
November  (1882)  the  skin  had  become  pliant  and 
smooth.  Only  on  the  legs  were  there  some  small  papules 
of  lichen  pilaris,  and  a  very  few  similar  papules  on  the 
arms.  All  the  cicatrices  had  become  pale,  and  on  the 
limbs  in  particular  a  great  number  had  entirely  disap- 
peared. 

Warts.— In  a  course  of  lectures  on  dermatology,  re- 
ported in  the  Medical  Ntws^  Dr.  Uuhring  says  that  ver- 
niers, or  warts,  either  hard  or  soft,  consist  of  variously 
sized  and  shaped  papillary  formations.  Verruca  vulgaris^ 
or  common  wart,  occurs  about  the  hands,  especially  on 
the  fingers.  Verruca  plana^  or  flat  wart,  is  found  on  the 
back  and  about  the  shoulders.  Verruca  filiformis^  con- 
sisting of  a  thin  thread  like  formation,  is  encountered  on 
the  eyelids  and  neck.  Verruca  digiiaia^  a  broad  excres- 
cence with  finger-like  processes  springing  from  the  bor- 
ders, is  found  upon  the  scalp.  Verruca  acuminafa^  also 
called  cauliflower  excrescence  and  venereal  wart,  is  a 
pinkish,  violaceous,  or  bright-red  fleshy  vegetation  occur- 
ing  usuallj'  about  the  genitalia  of  either  sex,  and  often 
accompanies  venereal  disease,  being  caused  by  purulent 
secretion  or  excessive  heat  and  moisture*  It  may  also 
occar  independent  of  any  venereal  disease.  It  takes  on 
various  forms,  and,  as  a  rule,  appears  like  the  head  of  a 
cauliflower  or  a  cock's  comb.  It  consists  of  a  proJifera- 
lion  of  the  epidermis,  the  development  being  rapid  ;  the 
papilla?  of  the  corium  and  the  corium  itself  are  also  greatly 
hypertrophied,  and  the  blood-vessels  dilated,  rendering 
the  growth  exceedingly  vascular.  The  most  satisfactory 
treatment  of  these  growths  is  excision,  and  cauterii^ing 
their  bases.  The  galvano-caustic  ligature,  chromic  or 
nitric  acid,  or  acid  nitrate  of  mercury  may  be  used.  The 
oleate  of  arsenic  is  also  said  to  act  very-  well.  In  the 
treatment  of  venereal  warts  astringent  lotions  together  with 
some  dusting  powder  are  highly  useful.  The  writer  has 
ein ployed  with  satisfaction  the  method  of  touching  these 
warts  with  nitrate  of  silver  and  covering  with  absorbent 
cotton, 

Chronu:  Intestinal  Catarrh.— Professor  Noth- 
nagel,  at  a  recent  meeting  of  the  Royal  and  Imperial 
Society  of  Physicians  at  Vienna  {Wiener  Med.  B/dUer), 
spoke  on  the  subject  of  chronic  intestinal  catarrh^which  he 
said  had  been  but  little  mentioned  in  text-books.  There 
is  also  no  explanation  given,  in  physiological  manuals, 
of  the  fact  that  healthy  individuals  have  generally  only 
one  stool  in  the  twenty-four  hours,  Nothnagel  thinks 
that  no  explanation  can  be  given,  but  that  it  is  one  of 
those  arrangements,  depending  partly  on  the  anatomical 
relations  of  the  parts,  and  partly  on  innervation,  for  which 
we  cannot  account.  Chronic  intestinal  catarrh  may  be 
considered  to  be  present  when  uuicus  appears  in  the 
motions,  although  the  absence  of  mucus  must  not  be  re- 
garded as  conclusive  evidence  against  the  existence  of 
catarrh,  Nothnagel  divides  the  cases  of  chronic  intes- 
tinal catarrh  into  four  classes  i  i.  Those  patients  who 
have  a  stool  every  second  or  third  day,  often  produced 
artificially  ;  this  is  the  type  of  primary  chronic  catarrh  of 


the  large  intestine,  and  depends,  accordiDg  to  Nothnagel, 
on  diminished  anatomical  activity  of  the  ganglion-cells. 
2.  Cases  where  a  stool  is  passed  daily,  but  each  time  thin, 
pulpy,  and  mixed  with  mucus.  3.  Cases  with  irregularity 
in  the  state  of  the  bowels,  sometimes  constipation,  some- 
times diarrhcea,  and  sometimes  an  alternation  between  the 
two  ;  the  diminished  activity  of  the  nerve-cells  explains 
the  constipation,  and  the  irritation  of  the  faeces  causes 
eventually  the  diarrhoea^  which  may  also  be  excited  by  a 
very  small  error  in  diet-  4,  Cases  with  continued  diar- 
rhcea. Here,  however^  chronic  ulceration  of  the  bowels 
must  be  distinguished  from  catarrh.  Where  diarrhoea  is 
present  without  ulceration  of  the  large  intestine,  Noth- 
nagel has  always  found  an  afi'ection  of  the  small  intestine 
as  well.  When  the  food  does  not  undergo  its  normal 
changes  in  the  small  intestine,  it  acts  as  an  irritant  on  the 
mucous  menibrane  of  the  colon,  and  causes  the  diarrhoea. 
Some  patients  have  a  stool  after  each  meal,  some  after  a 
mid-day  meal  only,  and  some  after  an  evening  meal  only. 
Nothnagel  would  explain  this  by  referring  it  to  nervous 
influence* 

Freckles, — Freckles,  or  lentigo,  may  sometimes  be 
made  to  disapt>ear  by  an  application  of  citrid  acid  night 
and  morning.  The  method  employed  by  dermatologists, 
and  attended  with  considerable  success,  is  to  apply  a 
solution  of  corrosive  sublimate,  one  to  three  grains  to 
the  ounce  of  water,  or  emulsion  of  almonds  night  and 
morning.  Dr.  Duhring  reports. the  latter  as  the  most 
satisfactory^  and  advises  its  application  until  a  slight 
^nount  of  desquamation  takes  place. 

Loosen iNG  of  the  Teeth. — Dr.  Sewill,  British  Med- 
ical Journal^  alludes  to  a  disease  which  appears  to  be 
on  the  increase  at  the  present  time,  and  is  characterized 
by  a  chronic  wasting  of  the  alveoli.  The  symptoms  com- 
nvence  with  inflammation  of  the  free  edge  of  the  gums 
and  the  alveolar  periosteum.  The  gums  and  alveoli 
slowly  waste  until  the  teeth  are  lost.  The  teeth  are 
commonly  of  good  structure  and  free  from  caries. 
There  is  in  many  cases  deposits  of  tartar  on  the  denuded 
surface  of  the  root,  and  beneath  the  swollen  and  loos- 
ened margin  of  the  gums.  As  a  rule,  several  teeth  are 
affected  at  the  same  time.  The  disease  commonly 
shows  itself  about  middle  life.  It  sometimes  accom- 
panies diabetes,  and  also  gout,  and  cases  of  debility  and 
an.^nua.  The  treatment  consists  in  periodically  removing 
the  tartar,  and  swabbing  the  necks  of  the  teeth  beneath 
the  loosened  gums  twice  a  week  with  pure  carbolic  acid. 

Foreign  Bodies  in  the  Bladder. — In  the  "Mittheil- 
ungen  aus  der  Chirurgischen  Klinik  zu  Tiibingen  "  is  con- 
tained a  paper  on  foreign  bodies  in  the  bladder,  based  on 
thirteen  cases  that  have  been  treated  in  the  Tubingen 
clinic  in  the  course  of  the  last  thirty  years.  The  term 
foreign  body  is  used  in  a  restricted  sense,  so  as  to  ex- 
clude stone  and  such  bodies  as  are  formed  within  the 
organism.  In  by  far  the  most  cases  the  foreign  body 
enters  the  bladder  by  the  urethra.  According  to  the  sta- 
tistics on  this  subject  published  in  1856  by  Denuc6,  of 
Bordeaux,  males  and  females  constitute  the  subjects  of 
this  injury  in  almost  equal  numbers.  In  males,  the  for- 
eign bodies  are  most  frequently  pieces  of  stalk  or  straw, 
wire,  lead-pencil,  and  in  females  any  of  the  different 
forms  of  needle  and  needle-case.  The  female  patients 
are  for  the  most  part  young,  while  most  of  the  men  are 
advanced  in  years.  In  six  of  the  thirteen  cases  recorded 
by  the  author  of  this  iiaiier,  the  foreign  body  had  passed 
into  the  bladder  by  the  urethra.  The  patients  in  three 
cases  were  males,  and  aged  resi)cctively,  forty-five,  forty- 
nine,  and  fifty-four.  Of  the  three  females  one  was  aged 
sixteen,  one  twenty-four,  and  the  last  twenty-five.  A 
much  smaller  group  is  that  of  cases  in  which  the  foreign 
body  consists  of  a  broken  and  detached  piece  of  some 
surgical  instrument,  as,  for  instance,  a  catheter,  bougie, 
or  sound,  a  lit  hot  rite,  caustic-holder,  etc  Catheters  of 
German-silver  become  very  fragile  after  having  been 
kept  long,  and  ought  not  then  to  be  used.     Of  elasdc 


October  i8,  i884,] 


THE   MEDICAL   RECORD. 


433 


catheters  and  boiijB^es,  Nilaton's  catheter  of  vulcanized 
caoutchouc,  after  it  has  been  kept  long  unused,  becomes 
extremely  fragile,  while  the  ordinary  elastic  bougies  be- 
come dan|;erous  only  after  frequent  use  and  prolonged 
retention  m  the  bladder.  Gutta-percha  catheter s^  it  is 
pointed  out,  are  particularly  dangerous.  In  niu^t  of  the 
cases  of  this  group  the  accident  is  owing  to  a  fault  rather 
of  the  patient  than  of  the  surgeon,  and  is  the  result  of 
loo  frequent  and  prolonged  use  m  catheterization  of  a 
worn-out  instrument.  The  author's  list  includes  five  of 
such  cases.  In  two  instances  the  foreign  body  was  the 
end  of  a  metal  catheter,  and  in  the  other  three  the  end 
of  an  elastic  catheter.  The  second  way  in  which  foreign 
bodies  may  reach  the  bladder  is  through  a  wound  in  the 
wall  of  this  organ.  The  injury  in  such  cases  is  either  a 
penetrating  or  a  gunshot  wound  The  penetrating 
wound  through  which  the  foreign  body  is  passed  ts  usu- 
ally caused  by  some  blunt  instrument  driven  into  the 
bladder  from  the  perineum  or  anus.  The  retention  of 
foreign  bodies  in  the  bladder  occurs  much  n)ore  fre- 
quently after  gunshot  wounds.  Of  zS^  cases  of  gunshot 
wound  of  the  bladder  collected  by  Bartels,  St  were 
complicated  by  retention  of  foreign  bodies,  consisting 
of  portions  of  the  fire-ami,  or  a  fragment  of  bone,  or  a 
small  portion  of  the  clothing.  Associated  with  the 
above  injuries  are  those  rare  instances  of  ruptured  blad- 
der complicated  by  fracture  of  the  pelvis,  in  which  one 
or  more  loose  fragments  of  bone  are  driven  into  the  vesi- 
cal cavity. 

The  third  and  least  frequent  way  in  which  a  foreign 
body  ckn  reach  the  bladder  is  through  a  pathological 
communication  between  the  bladder  and  neighboring 
organs.  The  foreign  body  in  such  cases  is  usually  some- 
thing that  has  been  swallowed,  and  has  ultimately  passed 
into  the  bladder  from  the  ileum  or  rectum  after  adhesion 
and  ulceration  of  their  walls.  By  perforating  ulceration, 
also,  foetal  remains  of  extra-uterine  pregnancy,  sequestra 
from  necrosis  of  the  pelvis,  and  the  contents  (teeth,  hair) 
of  dermoid  cysts  of  the  ovary,  have  penetrated  into  the 
bladder.  The  foreign  body  is  seldom  expelled  sponta- 
neously by  the  urethra.  Of  391  cases  of  foreign  body  in 
the  bladder  collected  by  Denuc6,  13  only  terminated  in 
this  way.  In  2  of  the  13  Tubingen  cases  there  was  a 
spontaneous  discharge.  The  foreign  body  in  one  case 
was  a  long  piece  of  metal  catheter  which  had  been  four 
weeks  in  the  bladder,  in  the  other  a  straw.  The  foreign 
body,  after  prolonged  detention  in  the  bladder,  becomes 
invariably  incrusted  with  linie<salts,  and  may  form  the 
nucleus  of  a  vesical  calculus.  Small  and  round  bodies 
are  soon  completely  incrusted,  while  long  Lhin  bodies 
are  incrusted  only  in  the  middle,  and  are  quite  free  at 
their  ends.  If  a  fragile  body,  a  straw  for  instance,  be 
broken  up  in  the  bladder,  each  of  the  fragmenis  may 
form  the  nucleus  of  a  distinct  stone.  The  rapidity  of 
the  incnistation  and  the  si^e  of  any  calculus  that  may  be 
formed  depends  on  the  nature  of  the  substance  forming 
the  nucleus.  Vegetable  material  becomes  rapidly  in- 
crusted, and  of  hard  materials  silver  and  gold  and  glass 
are  less  readily  incrusted  than  iron.  Beyond  this  in- 
crustation and  formation  of  stone,  the  presence  of  a 
foreign  body  in  the  bladder  very  seldom  gives  rise  to  any 
special  complication.  In  six  only  of  the  many  cases  col- 
lected by  Denuc6  was  death  due  to  the  direct  action  of 
the  foreign  body  on  the  wall  of  the  bladder.  Some  few 
instances  have  been  recorded  of  the  foreign  body  in  the 
bladder  of  the  female  having  penetrated  into  the  vagina. 
The  surgeon  having  assured  himself  of  the  presence  of 
a  foreign  body  in  the  bladder,  it  becomes  very  necessary 
for  him,  before  deciding  as  to  the  means  of  removing  it, 
to  make  out  its  size,  form,  consistence,  position,  and 
mobility.  This  may  be  done  by  digital  exploration  from 
the  rectum,  by  bimanual  examination  by  the  rectum  and 
anterior  wall  of  the  abdomen,  and  by  the  use  of  lit  ho* 
triptic  instruments.  The  endoscope,  Ur.  KnoUer  thinks, 
is  not  likely  to  prove  of  much  service  in  these  cases. 
The  last  and  most  difficult  problem  is  the  removal  of  the 


foreign  body  iy  the  readiest  and  least  dangerous  way. 

If  the  body  be  of  small  size,  and  have  not  been  long  in 
the  bladder,  the  surgeon  may  await  for  some  rime  the 
chance  of  its  being  passed  spontaneously  with  the  urine. 
To  favor  this,  a  large  thick  bougie  may  be  passed  into  a 
distended  bladder,  and  then  withdrawn  so  as  to  allow  the 
urine  to  rush  out  in  a  full  stream.  Extraction  by  the 
natural  passage  is  indicated  when  the  circumference  of 
the  foreign  body  does  not  exceed  the  cahbre  of  the 
urethra,  and  when  it  can  be  broken  up  within  the  blad- 
der. Since  the  introduction  of  UthotritVj  and  with  the 
progressive  improvement  in  the  instruments  used  in  this 
operation,  the  extraction  of  the  foreign  body  by  lithotomy 
has  been  less  frequently  performed.  The  statistics  of 
Denuc^  show  that,  while  before  1S30  extraction  was  per- 
formed in  aj^and  lithotomy  in  100,  out  of  127  cases; 
since  this  year,  out  of  122  cases,  extraction  was  practised 
in  TO  I  and  lithotomy  in  21.  In  dealing  with  a  foreign 
body  in  the  bladder  of  a  female,  Dr.  Kndller  vt^ouM 
advocate  forcible  dilatation  of  the  urethra,  introduction 
of  the  finger,  and  extraction  by  means  of  *ilender  forceps- 
— London  Medical  Rec&nf,  August  15,  18S4. 

Treatment  of  Acute  Inflammation  of  the  Knek- 
Jot  NT. — Dr.  Barwell  draws  attention  to  a  method  of 
treating  severe  inflammations  of  joints,  and  more  espe- 
cially those  of  the  knee.  In  a  sprain  or  wrench  of  a 
previously  healthy  joint,  a  severe  attack  of  synovitis  fol- 
lows, with  pain  and  swelling,  but  if  dislocation  takes 
place,  no  such  symptoms  follow,  for  the  torn  and  syno- 
vial membrane  permits  the  hypersecretion  of  the  in- 
flamed membrane  to  drain  away,  and  thus  relieve  the 
tension.  Acting  on  this  doctrine,  the  method  adopted 
by  the  author  is  as  follows  :  Suppose  the  knee  to  be  the 
injured  joint,  it  is  to  be  enveloped  in  a  broad  bandage 
of  elastic  webbing  \  or,  if  that  be  at  the  time  unattaiD* 
able,  an  ordinary  calico  bandage  will  answer  the  purpose, 
care  being  taken  to  leave  between  two  of  the  turns  a 
little  interval  on  ihe  inner  side  on  a  level  with  the  upper 
margin  of  the  |jatella.  At  this  point  there  is  passed  into 
the  joint  a  tubular  needle,  thoroughly  cleansed  and  asep- 
ticised.  The  fluid  runs  away  as  a  rule  easily^  and  when 
the  flow  has  ceased  the  needle  is  withdrawn,  the  puncture 
covered  with  strapping-plaster,  made  adherent  by  spread- 
ing on  it  turpentine  (a  potent  aseptic),  and  this  is  to  be 
painted  over  with  collodion.  Pressure  by  means  of 
strapping-plaster  must  then  be  applied  and  the  limb 
placed  at  rest  on  a  splint  for  a  few  days.  Dr.  Barwell 
strongly  urges  that,  in  all  cases,  joints  which  show  evi- 
dent marks  of  tension  should  be  evacuated  in  the  above 
manner.  Four  cases  are  cited  in  which  puncture  was 
performed,  the  results  being  that  in  a  few  days  the  pa- 
tients were  convalescent. — London  LanccL 


•   , 


HOMIEOPATHV   AND  THE  TREATMENT  OF  DVSENTERV. 

— ^Dr.  D,  A,  Baldwin,  of  Englewood^  N,  J,,  writes  us  con- 
cerning the  methodof  treating  dysentery  with  small  doses 
of  corrosive  sublimate,  as  recommended  again  recently 
by  Dr.  S,  B,  Childs,  Medical  Recokd,  August  23d. 
He  says  :  **  '  Hull's  Jahr,'  for  thirty  years  a  leading  man- 
ual of  homoeopathic  practicej  gives^  under  treatment  of 
dysentery,  mercurius  bichlo.  for  painful  bloody  stools, 
and  colocynth  for  the  griping  pains  and  tenesmus-  The 
editor  says  :  ^  A  successful  procedure  in  our  practice  is 
the  alternate  administration  of  colocynth  and  mercury 
for  many  forms  of  dysentery.  Coldcynth  first,  trit.,  alter- 
nate with  the  mercury^  when  the  griping  pains  and  tenes- 
mus are  intense,*  Every  work  of  homoeopathic  practice 
published  since  recommends  the  same/'  Dr.  Baldwin 
makes  the  extraordinary  charge  of  *^ gross  plagiarism,'^ 
based  upon  the  above.  The  charge,  however,  will  fit 
better  against  Jahr.  At  any  rate,  mercury  in  small  doses 
was  recommended  in  Trousseau's  *'  Treatise  on  Thera- 
peutics/^ and  was  used  more  than  thirty  years  ago  by 
Leclerc, 


m^^K:: 


'4m' 


THE  MEDICAL  RECORD. 


[October  i8,  1884. 


i  ■' 


The  Medical  Record: 

u4  Weekly  Journal  of  Medicine  and  Surgery. 
GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


PUBLISHRD  BY 

WM.'WOOD  &  Co..   Nos.  56  and  58  Ufayette  Place. 
^  ^    . ..     .  ...  ,    s 

New  York,  October  x8,  1884. 

V  THE  FINAL  REPORT  OF  THE  COLLECTIVE 
INVESTIGATION  COMMITTEE  ON  ACUTE 
LOBAR  PNEUMONIA. 

We  have  received  the  second  volume  of  the  "  Collective 
Investigation  Record,"  edited  by  the  Collective  Investi- 
gation Committee  of  the  British  Medical  Association.  It 
is  larger  than  the  first  volume,  and  distinctly  superior  to 
It  in  the  value  of  its  contents.  These  relate  to  the  sub- 
jects of  acute  pneumonia  and  puerperal  pyrexia.  The 
report  on  pneumonia  supplements  the  preliminary  report 
upon  this  subject  made  in  the  previous  volume.  At  that 
time  the  Committee  had  received  only  350  returns,  while 
the  present  volume  contains  the  analyses  of  715  more, 
making  1,065  cases  in  all.  Of  this  large  number  it  was 
found  that  the  returns  in  fourteen  cases  only  were  de- 
*fective.  There  was  left,  then,  an  unprecedentedly  large 
mass  of  data  upon  which  to  base  conclusions.  Never- 
theless, the  committee  in  their  final  summing  up  of  results 
•  is  wisely  cautious  in  estimating  the  value  of  the  infer- 
ences drawn.  A  good  deal  of  the  report  has,  as  is  ad- 
mitted, only  a  negative  value  ;  while  many  of  the  points 
elicited  were  already  known.  It  could  hardly  be  ex- 
pected, indeed^  that  any  extraordinary  facts  should  be 
brought  out  regarding  a  disease  which  has  for  centuries 
been  tirelessly  watched  by  so  many  competent  investiga- 
tors. 

There  are,  however,  some  facts  of  fundamental  impor- 
tance presented,  as  well  as  many  minor  details  of  con- 
siderable practical  interest. 

The  value  of  the  Committee's  report  is  much  enhanced 
'  by  several  original  communications  upon  the  subject  of 
the  alleged  zymotic  and  infectious  nature  of  pneumonia. 
Dr.  Octavius  Sturges  presents  a  concise  and  lucid  histor- 
ical paper  upon  epidemics  of  pneumonia  in  Great  Britain. 
Dr.  Sidney  Coupland  contributes  a  still  more  elaborate 
article  upon  foreign  epidemics.  A  report  of  two  epi- 
demics of  pneumonia  in  the  Punjab  is  made  by  Surgeon- 
Major  S.  R  Maunsell,  and  an  original  contribution  to 
the  subject  of  the  micro-organism  of  pneumonia  is  fur- 
nished by  Mr.  George  M.  Giles. 

Taken  altogether,  the  material  given  in  this  volume  of 
the  *'  Investigation  Record  "  marks  a  decided  advance  in 
our  knowledge  of  pneumonia,  and  future  clinical  writers 
or  lecturers  must  levy  tribute  upon  its  pages. 

We  present  some  of  the  main  facts  of  the  report,  fur- 
nished by  the  Committee  and  its  individual  members. 

It  is  evident  that  there  is  an  inclination  to  adopt  the 


conclusion  that  acute  lobar  pneumonia  is  not  the  simple 
and  single  entity  which  it  was  once  believed  to  be.  Thus 
Dr.  Sturges  refers  to  the  various  forms  of  epidemic  and 
contagious  pneumonia  under  three  heads,  viz. : 

1.  Epidemic  pneumonia,  occurring  in  districts  or 
houses  after  the  manner  of  epidemic  catarrh. 

2.  Pythogenic  pneumonia,  occasioned  by  sewer  gas, 
fecal  accumulation,  and  over-crowding. 

3.  Infectious  pneumonia,  imported  into  a  house  or 
district,  and  spreading  from  person  to  person.  Dr.  Stur- 
ges gives  a  brief  review  of  the  cases  which  have  been  re- 
ported in  Great  Britain,  favoring  the  view  that  pneumonia 
appears  under  the  forms  above  enumerated.  These  cases 
alone  are  not  numerous  enough  to  be  of  any  great  value, 
nor  is  it  pretended  that  they  form  more  than  a  link  in 
the  chain  of  evidence.  Dr.  Coupland  reviews  the  for- 
eign literature  covering  this  same  subject,  and  furnishes  a 
great  deal  that  is  more  positive.  In  the  same  line  with 
these  papers  are  tlie  reports  of  epidemic  pneumonia  in 
the  Punjab,  and  the  article  by  Dr.  Giles  on  the  miGro- 
organisms  of  pneumonia.  This  latter  gentleman  has 
made  microscopical  examinations  and  inoculation  experi- 
ments, which,  while  not  perfectly  in  harmony  with  those 
of  Friedlander,  do  on  the  whole,  he  believes,  corrobo- 
rate that  observer. 

The  evidence  as  to  the  infectious,  and  occasionally 
contagious  character  of  pneumonia,  furnished  by  the  re- 
turns, supports,  though  only  in  a  measure,  the  views  dis- 
cussed by  the  individual  contributors.  Out  of  the  1,065 
cases,  five  observers  only  speak  of  epidemics  of  pneumo- 
nia attributable  to  atmospheric  or  meteorological  condi- 
tions similar  in  character  to  influenza  epidemics.  Only 
three  observers  speak  of  '*  pathogenic  cases.'*  Nine  in- 
dependent observers  express  the  opinion  that  pneumonia 
is,  under  certain  circumstances,  capable  of  transference 
from  one  person  to  another.  Yet  these  gentlemen  make 
the  reservation  that,  possibly,  in  their  cases  it  was  only  a 
similarity  of  conditions  which  caused  the  apparendy  con- 
tagious attacks.  Despite  this,  as  it  appears  to  us,  some- 
what meagre  evidence,  the  Committee  feel  warranted  in 
believing  that  the  infectious  character  of  pneumonia  in 
some  cases  is  established,  and  that  it,  in  very  rare  in- 
stances, is  contagious.  We  reach  the  conclusion,  from  a 
survey  of  the  whole  evidence  here  furnished,  that  pneu- 
monia may  be,  and  generally  is,  simply  a  local  inflam- 
mation ;  that  in  other  cases  it  is  a  true  infectious  disease, 
a  pneumonic  fever ;  and  that,  Anally,  in  rare  cases  this 
infectious  fever  is  transmissible  from  person  to  person. 
It  is  shown  further  that  the  local  disease,  pneumonia, 
may  be  primarily  excited  by  exposure  to  cold,  etc. ;  or 
it  may  develop  secondarily  in  the  course  of  infectious 
fevers,  or  as  the  result  of  some  poison  or  other  de- 
pressing condition  acting  upon  the  vascular  or  nervous 
system. 

Such  are  the  more  striking  points  suggested  in  the  In- 
vestigation Record.  But  in  addition  a  good  many  other 
things  were  brought  out  by  the  analysis  of  the  returns. 
Thus  it  was  found  that  pneumonia  frequently  attacks 
more  than  one  member  of  a  household  at  the  same  time  ; 
that  when  unusually  prevalent  the  mortality  is  exception- 
ally low ;  and  that  defective  house  drainage  and  sewer- 
gas  poisoning  may  both  cause  and  favor  the  spread  of 
the  disease.   It  was  also  shown  that  alcoholic  excess  not 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


435 


only  favors  the  .development  of  pneumonia,  but  may 
actually  directly  cause  it;  and  that  fatigue. and  mental 
depression  rank  next  to  alcohol  in  making  the  prognosis 
unfavorable. 

The  total  mortality  among  the  i«o65  cases  was  192,  or 
I  in  5^.  Subtracting  from  these  the  105  alcoholic  cases^ 
the  14  cases  produced  by  mental  and  physical  depression, 
and  the  22  infectious  cases,  and  the  mortality  among  the 
remainder  was  108,  or  i  in  8. 

Aboat  one  patient  out  of  every  ten  had  suffered  from 
previous  attacks  of  pneumonia,  and  it  seems  to  the  Com- 
mittee safe  to  conclude  that  one  attack  predisposes  to 
another.  The  mortality  from  second  attacks  is  not 
greater  tha:n  from  first,  but  the  same  cannot  be  said  of 
third  attacks. 

As  regards  heredity,  there  is  no  evidence  that  the  dis- 
ease runs  in  families,  or  that  any  other  form  of  lung  dis- 
eases is  met  with  in  excess  in  the  families  of  those  who 
have  suffered  from  pneumonia. 

In  double  pneumonia  the  disease  runs  a  longer  course, 
and  is  more  liable  to  have  a  gradual  termination. 

Apex  pneumonias  were  found  to  be  as  favorable  in 
duration  and  mortality  as  other  forms ;  when  occurring 
in  phthisical  families  they  show  no  tendency  to  degen- 
erate into  phthisis,  and  phthisical  families  show  no  ten- 
dency to  have  apex  pneumonias.  These  conclusions 
ran  somewhat  counter  to  the  received  views  on  this 
point. 

In  another  respect,  also,  the  returns  are  at  variance 
with  the  usual  views,  and  that  is  as  to  the  mode  of  ter* 
luination  of  the  attacks.  Sudden  remission  is  not  the 
nile  in  pneumonia,  and  the  only  law  which  obtains  in 
this  regard  is  that,  when  the  pneumonic  pyrexia  has 
lasted  over  eight  days,  its  sudden  subsidence  is  improb- 
able. We  are  inclined  to  think  that  many  physicians,  in 
recalling  their  past  experiences,  will  not  be  surprised  at 
this  conclusion  of  the  returns. 

As  regards  treatment,  one  cannot  but  feel  some  disap- 
pointmeut  at  the  indefiniteness  and  valuelessness  of  the 
data  given. 

At  the  most  we  only  learn  what  are  the  most  popular 
measures  among  British  physicians,  without  in  the  least 
being  able  to  say  which  are  the  most  effective,  or  whether 
any  of  them  do  any  good.  As  regards  local  treatment, 
among  1,037  there  were  287  who  used  poultices  to  the 
chest;  1 1 7,  counter-irritants  ;  18,  leeches;  2,  wet-cup- 
ping; 9,  cold  sponging;  4,  wet-pack;  3,  warm  baths, 
and  2  vapor  baths. 

As  to  internal  or  general  treatment,  134  report  having 
used  the  ''  expectant"  plan — a,  rather  small  percentage 
for  so  excellent  a  method.  Ninety-four  used  the  ^<  support* 
ing  "  and  roborant  measures,  carbonate  of  ammonia  being 
one  of  the  drugs  most  relied  upon.  Indeed,  carbonate  of 
ammonia  w&s  used  by  250,  and  appears  to  be  more  uni- 
formly given  by  British  physicians  than  any  other  single 
remedy,  excluding  alcohol.  In  94  cases  antimonials  were 
prescribed^  Various  expectorants  were  used  in  2 14  cases, 
opium  in  60,  and  bromides  in  14  cases.  Antipyretic 
drugs  are  rather  in  favor.  Quinine  was  found  in  143  re- 
turns, aconite  in  125,  digitalis  in  65,  salicylic  acid  in 
4 1)  vcratria  in  4.  Ergot  was  given  in  9  cases,  bella- 
donna b  3,  phosphorus  in  2,  pilocarpin  in  i,  and  colchi- 
cumin  i. 


Alcohol  was  used  in  424  cases,  while  in  104  it  is  ex- 
pressly stated  that  no  stimulants  were  used. 

It  must  be  confessed  that  an  examination  of  the  re- 
turns of  treatment  leaves  one  with  a  poor  opinion  of  the 
value  of  British  skill  in  treating  pneumonia.  Either  they 
are  much  misrepresented,  or  the  professional  practice  is 
to  a  large  extent  hap-hazard,  and  dependent  on  the  pe- 
culiar education '  or  bias  of  the  practitioner.  It  is  cer- 
tainly strange  that  at  this  day  it  is  found  necessary  to 
use  from  twenty-five  to  thirty  drugs  in  pneumonia,  be- 
sides ** antiphlogistic"  or  "antipyretic"  measures. 


THE  NEW  LOCAL  ANAESTHETIC. 
When  we  have  heard  and  seen  what  the  local  appli- 
cation of  cocaine  hydrochlorate  has  done  in  abolishing 
pain,  we  are  in  danger  of  over-reaching  the  bounds 
of  reasonable  enthusiasm  regarding  its  merits  as  an 
anaesthetic  Such  of,  the  ophthalmologists  as  have 
tried  the  salt  cannot  speak  too  highly  of  its  wonderful 
power.  Since  the  letter  of  Dr.  Noyes  appeared  in  our 
last  issue,  the  ophthalmic  surgeons  have  been  vieing  with 
each  other  to  put  the  new  anaesthetic  to  the  severest 
test.  As  to  what  can  actually  be  accomplished  through 
its  agency  by  the  mere  instillation  of  a  few  drops  upon 
the  most  sensitive  conjunctiva,  is  perhaps  best  appre- 
ciated by  the  perusal  of  the  cases  reported  in  the  pres- 
ent issue  by  Drs,  Agnew,  Moore,  and  Minor. 

So  far  as  used  it  has  been  a  great  success,  and  there  is 
possibly  a  future  for  its  more  extended  application,  not 
only  in  ophthalmic  operations,  but  in  general  surgery.  But 
this  can  only  be  determined  by  actual  experience.  The 
test  for  its  still  wider'range  of  usefulness  is  yet  ta  be  made 
in  ophthalmic  practice.  If  its  power  to  control  pain  in  the 
operation  of  iridectomy  can  be  established,  the  impor- 
tance of  the  discovery  of  this  anaesthetic  will,  in  eye  sur- 
gery at  least,  rank  second  only  to  that  of  ether  itself.  On 
general  principles,  it  is  fair  to  assume  that,  by  increasing 
the  strength  of  the  salt  and  allowing  more  time  for  the 
manifestation  of  its  effects,  operations  of  the  class  men- 
tioned may  be  performed  without  pain  to  the  patient. 
At  least  it  appears  to  us  that  a  fair  trial  is  warrantable 
on  the  rational  presumptions  offered. 

It  is  not  reasonable  to  suppose  that,  even  from  the 
present  aspect  of  the  question,  we  shall  stop  here.  It  is 
quite  certain  that  in  those  numerous  cases  in  which  local 
anaesthesia  is  necessary  for  minor  operations  in  surgery, 
gynecology,  laryngology,  otology,  and  even  dentistry, 
this  anaesthetic  will  be  tested.  Especially  would  it  seem 
to  be  indicated  in  those  parts  of  the  body  which  are 
covered  by  mucous  membranes  and  plentifully  supplied 
with  sensitive  nerves. 

As  yet  we  know  little  or  nothing  of  its  possibly  poi- 
sonous effects  in  large  doses,  and  it  is  to  be  hoped  that 
no  rashness  in  experimentation  will  demonstrate  them. 
With  this  introduction,  cocaine  takes  its  place  in  the  Une 
of  new  remedies,  and  awaits  the  verdict  of  aft  impartial 
trial.  

THE  ORIGIN  OF  YELLOW  FEVER. 
The  unique,  mysterious,  and  at  the  same  time  deadly, 
character  of  yellow  fever,  by  which  it  is  separated  sa 
markedly  from  all  other  fevers,  has  led  to  the  most  zealous 
investigations  of  its  pathology.     Hardly  any  disease  has 


»#  ■-.••^rv 


436 


THE  MEDICAL  RECORD. 


[October 


18,    1884. 


called  forth  so  many  robustly  defended  and  statistically 
fortified  theories ;  in  fact,  yellow  fever  seems,  like  spir- 
itualism, to  have  a  tendency  to  unsettle  the  mind  of  the 
inquirer  and  turn  him  into  a  fanatic  over  his  own  spe- 
cial pathogenesis.  Yellow  fever,  unlike  other  infectious 
fevers,  lives  only  in  certain  regions  where  salt  water, 
vegetable  and  animal  decay,  and  tropical  warmth  exist ; 
even  these  do  not  furnish  all  the  elements  for  its  suste- 
nance. It  exists  only  in  the  sea-ports  of  the  tropical 
Atlantic  and  Western  Mediterranean,  from  which  places 
it  stalks  forth  in  the  summer  to  attack  other  regions. 
Since  1647  outbreaks  of  the  disease  have  occurred,  and 
it  has  been  a  terror  to  all  ships  trading  in  the  West  In- 
dies and  Gulf  of  Mexico.  In  many  of  these  West  In- 
dian ports  it  has  become  practically  endemic. 

Some  modern  sanitarians  have  been  disposed  to  treat 
the  subject  of  the  origin  of  this  disease  lightly,  and  to  deny 
the  possibility  or  need  of  ever  knowing  how  yellow  fever 
came  into  being.  Dr.  Chaille,  of  New  Orleans,  once  com- 
pared this  inquiry  to  that  of  "  the  origin  of  a  cat,"  which 
after  all  is  a  very  respectable  and  not  entirely  hopeless 
object  of  research.  Most  of  our  more  recent  writers  of 
text-books  evade  the  question  of  pathogenesis  altogether, 
or  give  the  vaguest  information  about  it. 
.  If  it  were  entirely  accepted  now  that  yellow  fever  does 
not  rise  i/e  novoy  the  question  of  its  origin  would  indeed 
have  little  mo]:e  than  an  historical  or  scientific  interest. 
Thus  those  who,  like  Dr.  Hargis  and  Mr.  Gamgee  in  late 
years,  have  claimed  that  the  disease  arises  in  ships,  can- 
not deny  that  the  conditions  for  producing  it  arise  anew 
each  year.  The  general  tendency  of  opinion,  however, 
is  certainly  against  the  ship  origin  or  the  de  novo  origin 
of  yellow  fever. 

In  the  October  number  of  the  North  American  Review, 
^T.  C.  Creighton  gives  a  very  interesting  and  vigorous 
exposition  of  another  hypothesis,  first  put  forward  by 
Audouard.  This  hypothesis  is  that  yellow  fever  arose 
from  the  slave-ships  which  carried  on  their  traffic  in  the 
last  and  the  early  part  of  the  present  century. 

The  arguments  put  forth  are  briefly  these  :  Yellow 
fever  is  a  disease  of  tropical  sea-ports,  but  limited  only 
to  a  few  of  them.  These  ports  of  yellow  fever  are  mostly 
the  old  ports  of  debarkation  in  the  slave  trade,  its  first 
appearance  being  at  Bridgetown,  twenty  years  after  slaves 
began  to  be  imported.  The  exacerbations  of  the  fever 
have,  as  a  rule,  corresponded  with  the  most  lawless  per- 
iods of  the  traffic. 

These  slave-ships  contained  hundreds  of  negroes  crowd- 
ed together  in  the  hold,  where  they  lived  in  filth  and  de- 
veloped unspeakable  stenches  from  the  accumulated 
excretions  of  their  bodies.  Cases  are  related,  showing 
that  under  these  conditions  a  form  of  cjiarrhoea  broke  out 
among  the  negroes,  and  that  then  yellow  fever  broke  out 
among  the  crew,  the  negro  himself  being  rarely  affected. 
These  slavers  having  arrived  at  port  with  their  crew  and 
cargo,  discharged  the  latter  and  then  cleaned  out  their 
ships,  pumping  the  bilge-water  and  the  accumulated  filth 
of  the  voyage  into  the  harbor.  This  being  done  for  years 
in  the  almost  tideless  harbor  of  Havana,  for  example,  the 
bed  and  shores  have  become  infected  with  the  specific 
germs,  by  which  the  disease  is  kept  endemic  and  the 
port  a  distributing  centre.  This  fatal  nmd,  says  Dr. 
Creighton,  has  long  been  washed  away  from  the  Dela- 


ware, from  Charleston,  and  all  other  Atlantic  ports.  It 
would  have  disappeared  from  the  Gulf  ports  but  for  the 
sluggishness  of  the  waters.  It  may  long  stay  in  the  West 
Indies  as  a  kind  of  Nemesis  for  the  horrors  and  cruelties 
of  the  "  middle  passage." 

Audouard's  theory,  thus  revived  and  eloquently  de- 
fended by  Dr.  Creighton,  contains  much  that  is  plausible. 

Certain  it  is  that  if  the  filth,  heat,  and  effluvia  gen- 
erated by  human  crowding  could  ever  originate  a  new 
disease,  a  specific  fever,  the  old  slavers  furnished  the 
conditions. 

The  objections  which  will  be  raised  are  that  the  theory 
is  too  narrow.'  A  single  case  well  substantiated  might 
upset  it.  The  old  slavers  might  well  have  originated 
yellow  fever,  but  can  we  say  that  they  were  its  only 
source  ? 

THi::  COMMA-BACILLUS  OF  CHOLERA  NOSTRAS. 

At  the  meeting  of  German  Naturalists  and  Physicians 
at  Magdeburg,  September  18  to  23,  Professor  Finkler,of 
Bonn,  made  a  most  important  communication  regarding 
the  cholera  bacillus.  He  announced  that  as  the  result 
of  a  series  of  experiments  made  by  Professor  Prior  and 
himself,  they  had  discovered  a  comma-bacillus  in  the 
stools  of  cholera  nostras.  They  had  cultivated  this  or- 
ganism on  gelatine  and  other  substances,  and  had  studied 
carefully  its  life-history.  Microscopically  it  was  identical, 
or  nearly  so,  with  Koch's  comma-bacillus.  In  its  growth, 
however,  it  finally  develops  spores,  and  after  a  time  only 
micrococci  are  to  be  seen  in  place  of  the  bacilli.  It  is 
claimed  that  these  spores  are  the  "  resting-state  "  of  the 
bacillus.  Cholera  stools  two  weeks  old  were  taken.  No 
bacilli,  but  only  micrococci  and  other  forms  were  found 
in  them.  Cultivations  were  made,  and  the  comma- 
bacilli  developed. 

Specimens  of  the  bacillus  of  cholera-nostras  have  been 
taken  to  Berlin  and  shown  to  Dr.  Koch,  who  acknowl- 
edges the  similarity  of  their  appearance  to  the  bacilli  of 
Asiatic  cholera. 

Inoculations  of  the  cultivated  bacilli,  made  by  Prior 
and  Finkler  in  dogs  and  rabbits,  have  as  yet  given  no 
decided  results. 

Prior  is  positive  that  the  disease  from  which  he  ob- 
tained the  organisms  was  cholera  nostras. 

The  significance  of  the  discovery  is  certainly  very 
great,  but  we  abstain  from  comment  until  further  partic- 
ulars reach  us. 

Dr.  Samuel  Morgan  Valentine,  born  in  New  York 
City,  and  a  resident  thereof,  died  in  Lucerne,  Switzer- 
land, August  7,  1884,  after  a  short  illness,  resulting  from 
disease  of  the  heart  He  was  graduated  from  the  College 
of  Physicians  and  Surgeons  in  1838,  and  after  a  thorough 
course  of  study  in  Europe  for  two  years,  returned  to  this 
country,  and  engaged  actively  in  practice,  till  other  mat- 
ters requiring  his  attention  he  was  obliged  to  relinquish 
his  professional  duties.  Though  long  living  a  retired 
life,  Dr.  Valentine  always  retained  his  interest  in  medi- 
cine, was  well  known  to  the  prominent  physicians  of  the 
city,  and  was  respected  for  his  sound  judgment  and  his 
many  kindly  qualities  of  character.  At  the  time  of  his 
death  he  was  still  a  member  of  the  New  York  County 
Medical  Society. 


October  i8,  1884.] 


THE  MEDICAL   RECORD. 


437 


lw)s  of  the  IMeck. 


The  Mississippi  Valley  Medical  Association,  at 
its  annual  meeting,  September  23-2 5th,  at  Springfield, 
111.,  elected  the  following  officers  :  President — Dr.  F. 
W.  Beard,  of  Indiana.  Vice-Presidents— Dr.  A.  B.  Mil- 
ler, of  Missouri ;  Dr.  J.  A.  Sutcliffe,  of  Indiana ;  Dr.  E. 
H.  Luckett,  of  Kentucky.  Secretary^Dv.  G.  W.  Bur- 
ton, of  Indiana.  Assistant  Secretary — Dr.  H.  J.  B. 
Wright,  of  Illinois.  Treasurer — Dr.  A.  M.  Owen,  of 
Indiana.  It  was  decided  to  hold  the  next  meeting  at 
Evans^alle,  Ind.,  on  the  second  Tuesday  of  June,  to  con- 
tinue three  days. 

The  Successor  to  the  Late  Professor  Cohnheim. 
—The  candidates  for  the  vacant  position  of  Professor  of 
Pathological  Anatomy  at  Leipsic  are  Rindfleisch,  Klebs, 
Ziegler,  and  Weigert.  Dr.  Koch's  name  has  also  been 
mentioned,  but  we  learn  by  cable  that  he  has  declined 
the  proffered  chair. 

Dr.  Alexander  H,  Stevens. — Dr.  A.  C.  Post  writes : 
"  Allow  me  to  correct  an  error  in  The  Record  of  October 
4th.  Alexander  H.  Stephens  was  a  distinguished  politi- 
cian of  Georgia.  Alexander  H.  Stevens  was  the  eminent 
New  York  surgeon.'* 

t  Cremation  of  Paupers. — It  is  proposed  as  a  measure 
of  economy  to  burn  the  dead  paupers  of  Brooklyn,  in- 
1  stead  of,  as  is  at  present  the  practice,  burying  them  in 
'  two-dollar  soap-boxes.  However  admirable  this  scheme 
might  be,  practical  men  will  see  the  futility  of  trying  to 
'  carry  it  out,  since  it  would  prevent  the  Brooklyn  politi- 
I      cians  from  making  their  usual  percentage  on  each  coffin. 

f  A  Field  for  Ophthalmology. — Professor  Mosely 
has  discovered  an  animal — a  mollusc — which  has  11,000 
eyes.     "  If  only  men  and  women  were  thus  poly-ocularly 

;      endowed,"  sighs  the  young  ophthalmologist. 

A  Case  of  Scarlet  Fever  in  a  Canary  is  reported 
by  Dr.  Frank  Ogston,  of  Aberdeen,  in  the  British  Medi- 
cal Journal.    The  bird  was  ip  a  room  where  two  children 

^  lay  sick  with  the  same  disease.  The  animal's  skin  was 
bright  scarlet,  its  throat  apparently  sore,  and  it  finally 
died. 

"  Vienna  '*  Surgery. — This  is  the  term  popularly  ap- 
plied in  this  city  to  "bold"  surgery,  1.^.,  such  as  is  done 
for  the  benefit  of  the  surgeon  rather  than  the  patient. 
We  are  glad  to  say  that  there  is  not  much  of  it  just  now. 

A  Proposed  Electro-therapeutical  Association. 
—It  is  proposed  to  hold  a  convention  of  physicians  at 
Waco,  Texas,  on  October  30th,  for  the  purpose  of  form- 
ing an  Electro-therapeutical  Association. 

Berlin  News. — The  Berlin  correspondent  of  the 
Allgemeiner  Wiener  Medizinische  Zeitung  writes  that 
Prince  Bismarck  recently  asserted  in  the  Reichstag  that 
medicine  had  made  no  progress  in  two  thousand  years ! 
The  same  correspondent  writes  that  the  week  in  Berlin 
has  been  a  very  quiet  one  ;  Professor  Schweninger  had 
received  no  new  decoration. 

A  Medical  President. — Dr.  Don  Rafael  Zaldivar, 
President  of  the  Republic  of  San  Salvador,  is  said  to  be 
a  very  accomplished  physician.  He  has  just  been  chosen 
for  a  third  term,  and  is  now  travelling  in  Europe. 


The  Harveian  Oration  was  delivered  this  year  on 
October  i8th,  by  Dr.  Russell  Reynolds. 

The  Acad6mie  de  MAdecine,  of  Paris,  held  a  meeting 
on  September  i6th.  M.  Hervieux  made  a  report  upon  re- 
vaccination.  He  gave  the  experiences  of  Surgeon-Major 
Burlureau,  who  in  210  cases  had  obtained  successful 
vaccinations  in  61.43  Ppr  cent.  M,  Hervieux,  among 
312  cases,  had  had  66.33  per  cent,  of  success.  The 
Academy  then  passed  to  the  subject  of  the  treatment  of 
cholera. 

Ten  Thousand  Dollars  for  Prizes. — The  sum  of 
40.000  francs  has  been  left  to  the  Faculty  de  M^decine, 
Paris,  to  found  a  biennial  prize  in  hygiene.  The  sum  of 
10,000  francs  has  been  left  for  a  prize  in  histology. 

The  Change  of  View. — **  Nearly  forty  years  ago," 
says  Dr.  R.  W.  Matthewson  in  the  Proceedings  of  the 
Connecticut  Medical  Society,  "I  had  the  honor  to  re- 
port the  name  of  Fordyce  Barker,  a  member  of  this 
Society,  for  Dissertator.  His  subject  was  *  Local  Treat- 
ment of  Uterine  Diseases  by  the  Speculum.*  This  was 
considered  such  an  innovation  on  old  customs  that  many 
of  his  friends  feared  it  would  injure  his  professional 
character.  When  Dr.  Bedfprd,  of  New  York,  .  first 
opened  his  clinics,  his  exposure  of  females  was  severely 
denounced  by  some  of  the  medical  journals." 

MiDwivES  in  Detroit. — Says  the  Detroit  Lancet: 
"  Since  the  training  school  for  nurses  has  opened  with  a 
liberal  endowment,  at  Harper  Hospital,  in  Detroit,  the 
nurses,  including  some  of  the  best  of  the  midwives,  have 
organized  themselves  into  a  society,  by  which  they  pro- 
pose to  emulate  the  attainments  of  the  graduates  of  the 
nursing  school.  They  have  procured  regular  instruction 
from  members  of  the  medical  profession  proficient  in  the 
art  and  science  of  midwifery.  They  are  said  to  be  quite 
particular  as  to  those  whom  they  admit  to  membership." 

The  Autopsy  upon  Cohnheim. — There  is  a  certain 
grim  satire  in  the  careful  accounts  of  the  post-mortem 
appearances  of  the  great  pathologist  Cohnheim.  Dr. 
Huber,  who  made  the  autopsy,  reports :  Contracted  gouty 
kidneys,  the  right  being  the  smaller  and  both  containing 
calculi,  arterio-sclerosis ;  extreme  excentric  hypertrophy 
of  both  ventricles ;  brown  induration  of  both  lungs,  on 
the  left  side  hydrothorax,  on  the  right  plenritis ;  infarction 
necrosis  in  the  left  kidney. 

The  Minnesota  College  Hospital  has  had  its  mort- 
gage foreclosed  and  it  is  financially  defunct.  The  city 
of  Minneapolis  is  not  large  enough  to  support  the  insti- 
tution. The  college  connected  with  it,  however,  con- 
tinues its  work. 

Another  Free  Medical  College. — The  Medical 
Department  of  the  University  of  Colorado,  at  Boulder, 
has  begun  its  sessions.  Tuition  is  free,  and  $6,200  have 
been  appropriated  to  build  a.  hospital. 

Another  Tri-State  Society. — A  movement  was  set 
on  foot  at  the  recent  meeting  of  the  Medical  Society  of 
Virginia  to  organize  a  Tri-State  Medical  Society,  repre- 
senting the  States  of  Virginia,  West  Virginia,  and  North 
Carolina. 

The  Chicago  Medical  Society  announces  that  there 
is  now  a  collection  of  twelve  hundred  standard  medical 
works  in  the  Public  Library, 


\'^ 


438 


THE  MEDICAL  RECORD. 


[October  i8,  1884. 


"1 


A  Slander  on  the  Texans. — Our  esteemed  but  fiery 
contemporsiry,  TAe  Texas  Courier- Record^  devotes  two 
or  more  pages  of  editorial  incandescence  to  the  wilting 
and  extinguishment  of  a  Philadelphia  professor  who  as- 
serted that  it  was  **  a  common  practice  in  Texas  for  the 
mothers  to  chew  the  food  for  the  children,  regurgitate  and 
spit  it  out,  and  then  feed  it  to  them."  The  editor  of  the 
Courier-Record  affirms  this  to  be  a  disgusting  and  in- 
famous slander.  He  further  expresses  a  deep  desire  to 
get  hold  of  the  author  of  the  slander  and  apply  a  coat  ot 
tar  and  feathers  in  a  manner  that  would  strain  the  most 
liberal  interpretation  that  could  be  put  upon  the  Code  of 
Ethics*  The  real  facts  seem  to  be  that  there  is  a  practice 
existing  in  several  Southern  Slates  on  the  part  of  mothers 
of  softening  a  bit  of  cracker  or  biscuit  in  the  mouth,  then 
giving  it  to  the  baby.  The  starch  in  the  cracker  is  turned 
to  sugar  by  the  saliva  and  the  infant's  food  partly  digested. 
This  procedure  is,  therefore,  claimed  to  be  physiological 
and  rational. 


COCAINE    HYDROCHLORATE  THE 
LOCAL  AN^:STHETIC. 


NEW 


{The  reports  of  the  following  cases,  illustrating  the 
surprising  effects  of  cocaine  hydrochlorate  as  a  local  an« 
aesthetic  in  ophthalmic  operations,  come  to  us  just  as  we 
go  to  press.  The  results  are  certainly  very  encouraging, 
apd  will  doubtless  command  the  attention  they  deserve. 
^Ed.] 

By  PkOFESSOR  C.  R.  AGNEW,  M.D., 


NBW    YOBK. 


In  your  last  issue  is  a  letter  from  our  distinguished 
colleague,  Dr.  H.  D.  Noyes,  in  which  there  is  an  allusion 
to  the  new  local  anzesthetic,  hydrochlorate  of  cocaine,  as 
recently  discovered  and  applied  in  Germany.  We  have 
to-day  (October  14,  1884)  used  the  agent  in  our  clinic 
at  the  College  of  Physicians  and  Surgeons,  with 
most  astonishing  and  satisfactory  results.  If  its  further 
use  should  prove  to  be  equally  satisfactory,  we  will  be  in 
possession  of  an  agent  for  the  prevention  of  suffering  in 
ophthalmic  operations  of  inestimable  value. 

^  It  is  difficult  to  avoid  expressions  of  extreme  enthusi- 
asm in  view  of  what  we  have  to-day  seen  and  in  view  of 
what  we  may  rationally  expect  from  the  further  applica- 
tions of  the  agent.  The  following  cases,  however,  will 
be  of  more  value  than  any  abstract  disquisition. 

Case  J. — A.  E ,  aged  five  ;  a  case  of  convergent 

squint  A  two  per  cent,  solution  of  the  hydrochlorate  of 
cocaine  was  dropped  upon  the  surface  of  each  eye  three 
times  at  intervals  jduring  a  period  of  fefteen  minutes, 
without  any  more  irritation  of  the  eyes  than  would  have 
been  caused  by  drops  of  common  water.  At  the  end 
of  twenty-five  minutes  he  walked  into  the  operating- 
theatre,  laid  down  upon  the  operating- chair,  and  allowed 
the  spring  speculum  to  be  inserted  between  his  eyelids, 
the  scleral  conjunctiva  to  be  seized  with  fixation  forceps 
and  cut  with  scissors,  and  the  rectus  internus  of  the  left 
eye  to  be  divided  without  complaining  or  showing  any 
signs  of  suffering.  When  we  had  the  internus  tendon 
upon  the  strabismus  hook,  he  said  we  were  pulling  some- 
thmg. 

Case   II. — L.  H.   B ,  aged    eleven  ;    convergent 

squint.  Solution  applied  as  above,  three  times  in  fifteen 
minutes,  at  the  end  of  which  time  he  sat  erect  in  a  chair, 
resting  his  head  upon  the  breast  of  an  assistant,  had  the 
speculum  inserted,  scleral  conjunctiva  seized  with  fixation 
forcep?,  and  the  internal  rectus  divided  in  the  usual 
manner,  and  when  asked  said  the  operation  had  given  no 
pain. 

Case  III. — Joseph  McC ,  aged  six;  convergent 

squint.    Solution  applied  as  above.    In  the  delays  of  the 


clinic  somewhat  more  than  half  an  hour  elapsed  between 
the  last  instiUation  of  the  agent  and  the  attempt  to  oper- 
ate«  The  youngster  seemed  to  be  much  frightened  by 
the  presence  of  the  surgeon  and  students ;  would  not  sub- 
mit to  the  proposed  strabotomy,  and  ether  had  to  be  ad- 
ministered before  it  could  be  done.  As  his  scleral  con- 
junctiva  was  insensible  to  the  contact  of  the  fixation 
forceps  fifteen  minutes  after  the  iirst  instillation  of  the 
solution,  it  is  a  fair  inference  that  the  anaesthetic  be- 
numbing had  passed  away  before  he  entered  the  operat- 
ing-theatre. His  nervous  apprehension  was  so  great 
that  he  would  not  have  endured  an  operation  even  though 
there  might  have  been  no  real  pain  inflicted. 

Case  IV. — James  McG ,  aged  fifty-two,  was  sent 

to  the  clinic  with  the  statement  that  he  had  a  lacerated 
wound  of  his  left  eyeball  involving  the  sclerotic.  His 
dread  of  handling  and  of  light  was  so  great  that  we  could 
get  no  view  of  the  injured  organ,  as  every  attempt  to 
inspect  it  was  instantly  followed  by  blepharo-spasni.  A 
few  drops  of  the  solution  were  instilled,  and  in  a  few  mo- 
ments the  patient  walked  into  the  operating-theatre  with 
the  injured  eye  open  and  so  free  from  irritability  as  to 
make  an  examination  of  it  before  the  students  quite 
easy. 

Case  V. — J ,  a  physician,  aged  seventy-one,  with 

double  cataract,  corfsulted  us  on  October  15th.  His 
eyes  were  extremely  sensitive  to  touch.  A  drop  of  the 
two  per  cent,  solution  was  dropped  upon  the  scleral 
conjunctiva,  and  in  two  minutes  and  a  half  the  patient 
permitted  me  to  apply  the  end  of  a  forefinger  to  the 
scleral  conjunctiva  without  wincing. 

The  solution  used  in  all  these  cases  was  a  two  per 
cent,  one,  made  with  distilled  water  and  with  Merk's 
crystals  of  the  hydrochlorate  of  cocaine. 

It  is  only  by  extensive  gathering  of  the  clinical  facts  in 
regard  to  this  new  agent  that  we  can  reach  just  conclu- 
sions as  to  its  value,  and  it  is  important  that  all  observers 
should  give  the  profession  the  benefit  of  their  experience 
The  operations  at  the  clinic  alluded  to  above  were  done 
with  the  assistance  of  Dr.  David  Webster,  Dr.  W.  Oliver 
Moore,  Dr.  Neil  J.  Hepburn,  and  Dr.  W.  A.  Pierrepont, 
and  in  the  presence  of  the  class. 


By  WILLIAM  OLIVER  MOORE,  M.D., 

PROFESSOR    OF    BYB    AND    BAR     DISEASES,    NRW    YORK    POST-GRADUATE    MEDICAL 
SCHOOL  AND  HOSPITAL. 

Cocaine  has  been  known  since  1855,  and  is  the  active 
principle  of  the  leaves  of  the  Erythroxylon  coca,  a 
South  American  plant,  the  leaves  of  which  resemble  very 
much  those  of  the  tea  plant.  Many  of  the  natives  dur- 
ing hard  work  use  these  leaves,  chewing  them  with  some 
alkaline  substance,  going  without  food  the  entire  day, 
but  taking  their  food  at  night.  It  has  long  been  known 
as  a  powerful  stimulant.  Cocaine  hydrochlorate  is  of 
more  recent  origin,  and  the  anaesthetic  effect  of  it  when 
brushed  or  dropped  upon  mucous  surfaces  has  been 
only  known  about  a  year,  it  having  been  used  in 
Germany  first  by  the  laryngologists,  to  produce  anaes- 
thesia of  the  vocal  cords  and  surrounding  parts  to  fa- 
cilitate manipulation.  "^  In  this  journal,  page  417,  in  a 
letter  from  Dr.  H.  D.  Noyes,  of  New  York,  an  accoimt 
is  given  of  an  experiment  made  with  this  drug  before  the 
Ophthalmological  Congress  at  Heidelberg,  where  a  so- 
lution of  the  cocaine  hydrochforate  was  dropped  into 
the  eye,  the  result  being  complete  anaesthesia  of  the 
conjunctiva  and  cornea.  Dr.  Noyes  is  justly  enthusiastic 
on  the  subject,  and  his  letter  caused  me  to  obtain  some 
of  the  drug  for  experimentation,  the  results  being  an- 
nexed. 

A  two  per  cent,  aqueous  solution  of  the  cocaine  hy- 
drochlorate (Merk*s)  is  procured  and  dropped  into  the 
eye,  two  drops  being  sufficient  at  first ;  the  eye  is  then 
closed,  and  in  five  minutes  two  more  are  instilled ;  after 
five  minutes  more  have  elapsed,  as  a  rule,  anaesthesia  is 
complete  ;  if  not,  two  more  drops  may  be  used.  There 
is  no  pain  attending  the  application.  ^ 


October  i8,  1884.] 


THE  MEDICAL  RECOka 


439 


The  following  experiments  were  made  with  very  satis- 
factory results : 

Case  I. — Chinaman,  with  keratitis.  Two  drops  of  a 
two  per  cent,  solution  of  the  cocaine  hydrochlorate  were 
(Jropped  into  the  left  eye,  then  closed ;  after  five  minutes 
two  more  drops  were  used  ;  at  the  end  of  fifteen  minutes 
from  the  first  instillation  I  was  able  to  grab  the  ocular 
conjunctiva  with  fixation  forceps  and  move  the  eye  in 
any  direction  without  pain  or  any  disagreeable  sensation. 
The  ulcer  of  the  cornea  was  also  touched  and  gently 
saaped  without  sensation.  In  the  right  eye,  where  none 
of  the  drug  had  been  used,  the  patient  made  loud  demon- 
strations of  complaint  on  my  attempt  to  use  the  fixation 
forceps,  as  in  the  first  instance ;  in  short,  there  was  a 
marked  difference  in  the  eyes.  The  anaesthetic  effect 
in  the  right  eye  had  entirely  disappeared  in  thirty-two 
minutes  from  the  beginning  of  the  experiment. 

Case  II. — Man,  aged  thirty-seven,  with  double  ptery- 
gium. In  one  eye,  the  left,  1  put  in  two  drops  of  the  so- 
lution, and  after  waiting  five  minutes  introduced  between 
the  lids  two  drops  more ;  after  another  interval  of  five 
minutes  two  more  were  used. 

Five  minutes  after  the  last  drops  were  used  the  opera- 
tion was  begun,  the  pterygium  being  excised  by  scissors, 
the  conjunctiva  being  freely  cut,  and  the  cut  surfaces 
brought  together  by  three  sutures.  This  usually  painful 
operation  was  done  with  the  utmost  ease,  and  without 
any  painful  sensation,  the  patient  being  surprised  at  its 
completion. 

In  the  other  eye  the  cocaine  was  not  used,  and  the 
pain  and  suffering  of  the  patient  was,  as  usual,  when  ether 
is  not  used.  The  effect  was  very  marked,  and  really  very 
surprising.     The  anaesthesia  lasted  twenty-five  minutes. 

Case  III. — Child,  seven  years  old,  having  squint  (stra- 
bismus convergens^.  Two  drops  of  the  solution  were 
put  into  the  squintmg  eye,  and  repeated  as  in  the  other 
cases  till  six  drops  in  all  had  been  used  during  the  space 
of  fifteen  minutes ;  at  the  end  of  which  time  the  con- 
junctiva was  sufficiently  quiet  to  allow  of  the  tenotomy 
of  the  internal  rectus  muscle,  the  usual  operation  being 
performed,  the  spring  speculum  being  used.  The  little 
boy  made  no  complaint  of  pain,  and  simply  said  the 
speculum  stretched  the  lids,  but  was  painless.  That  it 
is  unusual  for  a  child  of  this  age  to  allow  an  operation  of 
this  sort  to  be  done  without  ether  is  at  least  a  marvel, 
and  to  show  that  the  patient,  though  young,  had  not 
"  pure  grit  "  the  other  eye  (the  ope  in  which  no  cocaine 
had  been  used)  was  tried,  and  found  to  have  the  normal 
sensations. 

I  have  tried  it  in  other  cases,  yet  this  will  suffice  to 
bring  it  before  the  notice  of  the  profession  at  once.  Sev- 
eral of  my  confreres  at  the  New  York  Eye  and  Ear  In- 
firmary and  elsewhere  have  used  the  same  solution  with 
good  effect.  Much  more  will  be  written  on  this  subject, 
as  it  has  a  wide  application,  and  we  have  yet  to  learn 
much  of  the  properties  of  the  alkaloid.  The  introducer 
of  this  new  and  truly  magical  preparation  is  a  student  in 
Vieima,  Dr.  KoUer,  vide  Dr.  Noyes'  letter  above  referred 
to.  I  hope  to  say  more  of  its  practical  value  at  another 
time,  i 


By  JAMES   L.   MINOR,    M.D., 

ASSISTANT  SURCBON,  MBW  YORK  EYB  AND  BAR  INFIRMARY. 

The  last  number  of  The  Record  contained  a  short 
account  of  the  proceedings  of  the  Heidelberg  Ophthalmo- 
logical  Congress,  by  Dr.  H.  D.  Noyes.  He  speaks  of 
the  anaesthetic  effects  of  the  muriate  of  cocaine,  and  of 
its  probable  future  in  ophthalmology. 

I  have  had  an  opportunity  of  using  the  drug  on  several 
cases,  and  with  such  beneficial  effect,  that  I  deem  it  im- 
portant enough  to  lay  before  the  readers  of  The  Rec- 
ord. 

I  used  a  two  per  cent,  solution,  kindly  furnished  me  by 
Dr.  Moore,  after  the  manner  described  by  Dr.  Noyes — 
viz.  :  two  drops  were  dropped  into  the  conjunctivad  sac. 


and  in  ten  minutes  this  was  repeated,  and  the  operation 
was  performed  ten  minutes  later. 

Case  I. — A  nervous  boy,  aged  ten,  upon  whom  I  had 
operated  for  squint  in  the  left  eye  three  days  before, 
presented  himself  on  October  13th)  with  the  conjuncti- 
val stitches  still  in  situ.  The  solution  of  cocaine  was 
instilled  as  above  described.  The  cornea  and  the  con- 
junctiva could  be  brushed  with  the  end  of  the  finger, 
without  causing  any  uncomfortable  sensation.  The 
speculum  was  introduced,  the  stitches  removed,  the  con- 
junctiva was  grasped  with  fixation  forceps,  and  the  globe 
was  pulled  around  by  them.  The  child  complained  of 
no  pain,  and  when  asked  after  it  was  over  if  he  had  been 
hurt,  he  replied  in  the  negative.  The  other  eye  retained 
ils  sensibility,  and  it  could  not  be  handled  in  the  least. 

Case  II. — A  woman,  aged  fifty,  upon  whom  I  had  per- 
formed a  preliminary  iridectomy  a  few  weeks  before, 
came  for  the  extraction  of  the  cataract  on  October  13th. 
She  was  nervous  and  very  resentful  of  anything  disagree^ 
able  or  painful.  When  the  iridectomy  was  performed,  I 
attempted  to  do  it  without  an  anaesthetic,  but  found  it 
utterly  impossible  to  even  retain  the  speculum  between 
the  lidS;  and  resorted  to  ether.  I  decided  to  use  the 
cocaine,  and  dropped  it  in  the  eye,  on  which  she  shrank 
back  and  closed  the  eye  as  tight  as  possible — resenting 
even  this  much  handling  of  the  eye — for  the  solution  is 
non-irritating  to  the  conjunctiva.  The  second  applicatron 
was  made  without  difficulty,  and  I  could  rub  my  finger 
over  the  conjunctiva  and  cornea  without  causing  discom- 
fort. The  speculum  was  introduced,  the  conjunctiva  was 
grasped  with  fixation  forceps,  and  the  globe  thus  pulled 
in  position.  A  large  section  of  the  cornea  was  made, 
and  cystotomy  and  delivery  of  the  lens  were  easily  ac- 
complished. The  patient  complained  of  no  pain,  and 
after  the  operation,  and  on  the  following  day,  declared  that 
she  had  not  been  hurt  in  the  least  She  was  even  sur- 
prised when  told  that  the  operation  had  been  performed. 
Immediately  after  the  operation  I  tested  the  sensibility 
of  the  conjunctiva  of  the  other  eye,  by  lightly  touching 
it  with  my  finger.  She  shrank  and  closed  the  eye  so 
quickly  and  violently  that  I  feared  the  other  eye  would 
suffer  from  the  violent  contraction  of  the  lids.  The  case 
has  progressed,  so  far,  as  satisfactorily  as  could  be  de- 
sired. 

Should  cocaine  in  the  hands  of  others  meet  with  the 
same  success  that  I  have  attained,  it  will  mark  an  era  in 
ophthalmology  unsurpassed  by  any  in  modem  times.  Its 
use  in  other  branches  of  medicine  and  surgery  may  be 
almost  as  important  as  in  ophthalmology. 

233  Madison  Avbmub,  Nbw  York,  October  15, 1884. 


AMERICAN   PUBLIC   HEALTH   ASSOCIATION. 

Twelfth  Annual  Session,  held  at  St.  Zouisy  Mo.^ 
October  14,  15,  16,  and  17,  1884. 

(By  Telegraph  to  The  Mboicai.  Rbcoro.) 

Tuesday,  October  14TH — First  Day. 

The  session  was  called  to  order  at  10  a.m.  Dr.  Albert 
C.  Ghion,  presiding.  About  one  hundred  and  fifty  mem- 
bers were  present. 

Dr.  J.  Spiegelhalter,  of  the  Local  Committee,  wel- 
comed the  members  and  announced  the  programme  for 
the  session. 

An  appointed  committee  recommended  that  members 
residing  in  the  District  of  Columbia  form  into  a  body 
and  secure  incorporation  of  the  Association.     Adopted. 

Dr.  J.  Zerrien  Lindsley,  the  Treasurer,  reported  a 
balance  on  hand  with  an  admission  of  one  hundred  and 
twenty-five  new  members. 

The  Committee  on  Necrology  reported,  showing  four- 
teen deaths. 

The  Conference  of  Charities  and  Corrections  at  present 
in  session  was  invited  to  attend  the  meetings  of  the  Asso- 
ciation. 


44C 


THE   MEDICAL  RECORD 


[October  i8,  1884. 


Dr^  Charles  W.  Chancellor,  of  Maryland,  read  a 
paper  on 

TENEMENT   REFORM, 

dealing  with  the  squalid  dwellings  of  the  poor,  their  un- 
sanitary condition,  and  vice  resulting  therefrom. 

Major  Samuel  I.  Robinson,  of  the  District  of  Colum- 
bia, read  a  paper  on 

THE   HYGIENE   OF  THE   HABITATION'S   OF   THE   POOR, 

abounding  with  practical  suggestions  regarding  drainage, 
ventilation,  etc. 

Dr.  William  K.  Newton,  of  New  Jersey,  read  a 
paper  on 

THE    SANITARY   SURVEY   OF   A    HOUSE, 

urging  that  a  sanitary  history  of  all  houses  should  be 
kept  by  municipalities. 

The  above  papers  were  discussed  by  Dr.  Hunt,  of 
New  Jersey  ;  Erastus  Brooks,  of  New  York  ;  Dr.  Reade, 
of  Ohio ;  Dr.  Fee,  of  Kansas  City  ;  Dr.  A.  N.  Bell,  of 
New  York ;  Dr.  Raymond,  of  Brooklyn  ;  Dr.  Briggs,  of 
St.  Louis  ;  Dr.  Devron,  of  New  Orleans ;  Dr.  Bryce, 
of  Toronto  ;  Dr.  Cook,  of  Nashville. 

Mr.  Brooks  introduced  the  question  of 

LICENSING    PLUMBERS, 

instancing  the  good  results  following  in  New  York. 
Dr.  George  H.  Ronfi  read  a  paper  on 

THE    hygiene    of   OCCUPATIONS, 

giving  statistics  of  average  life  expectation  of  the  various 
trades  and  professions. 

Dr.  Adolph  Alt,  of  Missouri,  read  a  paper  on 

protective  spectacles  for  workingmen, 

recommending  that  employers  be  made  to  force  men  in 
their  employ  to  wear  protective  spectacles  wherever 
there  is  danger  from  flying  chips. 

Prof.  Charles  O.  Curtman,  of  St.  Louis,  read  a 
paper  on 

heating  and  ventilation. 

/  The  hot  air  principle  is  considered  the  best  for  public 
buildings. 

Dr.  VV.  Thornton  Parker,  of  the  U.  S.  Army,  read  a 
paper  on 

SANITARY  management  OF  RAILWAY  CARS  AND  STATIONS. 

He  dealt  with  the  danger  of  moving  sick  and  convales- 
cents in  ordinary  cars,  and  urged  sanitary  inspection  of 
all  trains  and  adoption  of  hospital  cars. 
The  Association  then  adjourned. 


Evening  Session. 

At  8  p.m.  the  hall  was  crowded  with  visitors,  many 
ladies  being  present. 

ADDRESSES   OF  WELCOME 

were  made  by  the  Mayor  of  the  city,  Governor  of  the 
State,  President  of  the  State  Board  of  Health,  and  others. 
A  band  of  music  enlivened  the  occasion. 

The  feature  of  the  evening  was  the  address  by  the 
President,  Dr.  A,  L.  Gihon,  which  was  listened  to 
closely,  and  frequently  applauded. 


October  15TH — Second  Day. 
Papers  were  read  on 

school  hygiene 
as  follows :  "  Report  of  Committee  on  Compulsory  Vac- 
cination," by  Dr.  Geo.  H.  Homan,  of  St.  Louis ;  "  Hygiene 
of  Eyesight  of  School  Children,"  by  Dr.  Stephen  O. 
Richey,  of  Washington,  D.  C. ;  "Sanitary  Survey  of  the 
School-houses  of  Indiana,"  by  Dr.  E.  S.  Elder,  of  India- 
napolis ;  "  School  Hygiene,"  by  Dr.  Felix  Formento,  of 
New  Orleans,  La. 


THE   food   question 

was  discussed  under  the  following  heads :  "  Cotton-Seed 
Oil  as  Food,"  by  Prof.  C.  E.  Munroe,  of  Annapolis,  Md.- 
"  Poisonous  Cheese,  Canned  Beef,  Sausage,  etc.,"  by 
Prof.  V.  C.  Vaughn,  of  Michigan  ;  "  Milk  Supply  of  Large 
Cities,"  by  Dr.  Chcston  Morris,  of  Philadelphia,  Pa, 

Afternoon  Session. 
On  invitation,  Dr.  J.  V.  McCormack,  of  Kentucky, 
read  a  report  adopted  by  the  Conference  of  States  Board 
of  Health  relating  to 

THE   BEST   MEANS   OF   PREVENTING  THE   APPEARANCE  OF 
CHOLERA   IN  THIS   COUNTRY. 

The  report  of  the  Conference  stated  that  there  were  three 
essential  factors  to  the  prevalence  of  cholera  :  i,  The  im- 
portation of  the  disease  by  means  of  ships  ;  2,  local  un- 
sanitary conditions ;  3,  persons  sick  with  the  disease,  or 
things  infected  by  such  sick  persons.  In  view  of  the 
threatened  introduction  of  cholera  into  this  country  dur- 
ing the  coming  year,  it  was  the  sense  of  the  committee 
that  the  Government  should  maintain  a  national  health 
service,  which  should  establish  an  effective  system  of 
quarantine  bv  the  appointment  of  medical  ofllicers  at  for- 
eign infectea  ports ;  that  emigrants  shall  be  prevented 
from  landing  until  the  danger  of  the  introduction  of 
chplera  has  been  ascertained.  The  inspection  and  quar- 
antine service  inaugurated  by  the  National  Board  of 
Health  met  with  the  approval  of  the  committee,  which 
recommended  that  Congress  be  urged  to  appropriate 
$500,000  to  be  used  for  the  purpose  of  stamping  out  the 
disease  should  it  become  epidemic. 

The  committee  was  of  the  opinion  that  State  Sanitary 
Inspectors  should  be  appointed  to  visit  all  towns  and 
cities  especially  liable  to  the  disease  to  consult  with  the 
local  authorities  as  to  the  best  methods  of  prevention. 
This  work  should  be  vigorously  prosecuted  before  the 
disease  reached  the  American  shores.  The  report  also 
recommended  the  isolation  of  victims  of  the  disease,  and 
the  destruction  of  their  clothing  and  the  discharges  from 
their  bodies. 

The  Association  unanimously  endorsed  the  report  of 
the  States  Board  of  Health  Conference,  and  a  motion 
was  adopted  that  said  report  be  printed  and  copies  of  it 
sent  to  the  United  States  Cabinet  officers,  Members 
of  Congress,  and  all  State  and  local  Boards  of  Health  of 
this  county  and  Canada. 

A  motion  by  Dr.  Hibberd,  of  Indiana,  to  appoint  a 
committee  to  report  on  antiseptics  and  germicides,  was 
referred  to  the  Executive  Committee.  The  rest  of  the 
session  was  devoted  to  reports  from  the  various  States 
on  the  progress  of  sanitation  during  the  past  year. 

THE   PAPERS    READ   AT  THE   EVENING    SESSION. 

An  audience  of  one  hundred  and  fifty  was  present,  in- 
cluding quite  a  number  of  ladies.  Papers  were  read  as 
follows  :  "  The  Food  we  Eat  and  the  Adulterations  to 
which  we  Submit,"  by  Hon.  Erastus  Brooks,  of  New 
York ;  "  The  Hygiene  of  Sailors  engaged  in  the  Coast- 
ing Trade,"  by  Dr.  Walter  Wyman,  U.  S.  Marine  Hos- 
pital Service  ;  ''  Cremation  as  a  Safeguard  against  Epi- 
demics," by  Rev.  John  D.  Bengles,  Chaplain  U.  S. 
Navy;  **The  Ultimate  Sanitation  by  Fire,"  by  Hoa  J. 
M.  Keating,  of  Memphis,  Tenn.  These  papers  were 
discussed  and  the  Society  adjourned  at  1 1  p.m. 

HOW  THE   MEETING   IS   ATTENDED. 

The  attendance  of  members  is  quite  large,  but  little  local 
interest  is  manifested  in  the  proceedings.  Toward  the  end 
of  the  afternoon  session  there,  were  not  more  than  twentj 
members  left  in  the  hall,  and  these  would  have  been  left 
in  the  dark  if  a  non-member  had  not  taken  upon  himself 
the  duty  neglected  by  the  local  Committee  of  Arrange- 
ments. The  papers,  as  a  rule,  are  carefully  prepared 
and  of  practical  value,  but  the  discussions  are  spiritless. 
The  usual  social  entertainments  and  courtesies  are  not 
neglected. 


October  i8,  i884,] 


THE   MEDICAL  RECORD, 


441 


Reports  ot  SiocUtUs. 

NEW  YORK  PATHOLOGICAL  SOCIETY. 

SiUfd  Meetings  September  24,  1884. 

George  F.  Shrady,  M.D.,  President,  in  the  Chair. 

SARCOMA  OF  THE   MEDIASTINUM   AND   LUNG. 

Dk.  Van  Gieson  presented  a  specimen  accompanied 
by  the  following  history,  and  for  both  he  was  indebted  to 
Dr.  W.  F.  French,  House  Physician  at  St  Catharine's 

Hospital,  Brooklyn,  N.  Y. :  D.  N ,  forty-one  years 

of  age,  married,  German,  was  admitted  September  1 1, 
1884.    On  examination  the  chest  revealed  the  following 
physical  signs :  over  the  upper  lobe  of  the  right  lung 
there  was  entire  absence  of  respiratory  movement,  ab- 
sence of  vocal  fremitus,  complete  dulness,  and  absence 
of  respiratory  sounds,  unaltered  by  change  of  position. 
The  patient  was  emaciated,  and  had  oedema  of  the  left 
apper  eyelid  and  orbital  region.     There  was  no  oedema 
of  the  extremities.     There  was  tympanites,  dyspnoea, 
cough  without  expectoration,  nausea  without  vomiting. 
The  left  side  of  the  thorax  was  normal.     There  was  no 
family  history  of  cancer.     There  were  no  symptoms  re- 
ferable to  the  uterus.     The  patient  died  September  16, 
1884.    The  autopsy  was  made  on  the  17th.     Body  ema- 
ciated, and  rigor  mortis  only  slight.     Head  and  uterus 
not  examined.     The  heart  was  normal ;  the  pericardium 
contained  eight  ounces  of  clear  senim.     Lungs :  Out- 
side of  the  pericardium,  in  the  anterior  mediastinum, 
there  was  a  mass  of  infiltrated  glands,  about  the  size 
of  the  fist.     In  the  anterior  portion  of  the  upper  lobe 
of  the  right  lung  was  a  dense  infiltration  in  the  form  of 
filbert-shaped  nodules  of  a  white  color,  and  bound  to- 
gether with  a  fibrous  stroma.     The  growth  was  regarded 
as  cancerous.     The  remaining  portion  of  the  right  lung, 
with  the  exception  of  a  few  adhesions  at  the  base,  was 
apparently  healthy.     The  left  lung  was  apparently  nor- 
mal.   The  bronchial  glands  were  involved.     The  right 
bronchus  was  constricted  to  the  size  of  a  No.  8  English 
nrethral  sound.     The  spleen  and  kidneys  were  normal, 
and  the  liver  was  slightly  fatty. 

Dr.  Van  Gieson  remarked  that  the  fact  that  the  uterus 
was  not  examined  might  give  rise  to  doubt  as  to  whether 
or  not  the  patient  might  not  have  had  cancer  of  that  or- 
gan ;  there  was  nothing  in  the  clinical  history,  however, 
which  turned  the  attention  of  the  house  staff  in  that 
direction. 

Microscopical  examination,  so  far  as  it  had  been 
made,  determined  the  growth  in  the  thorax  to  be  sar- 
coma rather  than  cancer. 

The  absence  of  vocal  fremitus  was  a  feature  of  interest 
in  the  clinical  history,  and  it  could  be  accounted  for  by 
the  constriction  of  the  bronchus.  In  another  case  seen 
with  him  by  Dr.  Jane  way  in  consultation,  the  same  con- 
dition of  absence  of  vocal  fremitus  was  noticed,  and  that 
fact  aided  somewhat  in  the  diagnosis. 

The  President  remarked  that  the  new  growth  prob- 
ably began  in  the  mediastinum. 

Dr.  Van  Gieson  said  that  was  the  opinion  of  the  gen- 
tlemen who  made  the  microscopical  examination. 
The  President  asked  if  the  bones  were  examined. 
Dr.  Van  Gieson  thought  they  were  not.    There  was 
no  evidence,  however,  of  disease  of  either  the  sternum 
or  the  ribs. 

The  President  regarded  sarcoma  of  either  the  lungs 
or  the  mediastinum  as  quite  rare,  independent  of  the  pre- 
vious existence  of  the  disease  in  some  other  part  of  the 
body,  especially  the  bones. 

Dr.  Van  Gieson  remarked  that  in  a  somewhat  similar 
case  oedema  of  the  eye  without  protrusion  was  noticeable, 
and  there  was  no  evidence  of  new  growth  in  the  cellular 
tissue  of  the  orbit.  In  that  case  the  oedema  was  ac- 
counted for  on  the  ground  of  pressure  upon  the  blood- 
vessels of  the  neck. 


acute  phagedenic  pustular  syphilidb. 
Dr.  John  A.  Wyeth  presented  a  patient  with  the  fol- 
lowing history :    Samuel  J ,   bookkeeper,  German, 

thirty*five  years  of  age.  Was  admitted  to  Mt.  Sinai  Hos- 
pital July  1 1 , 1 884.  Previous  to  the  present  attack  he  had 
had  illicit  intercourse  fi-equently,  had  had  gonorrhoea  many 
times,  the  last  attack  being  nine  months  ago.  He  had 
had  no  urinary  trouble  at  any  time.  Five  weeks  and  a 
half  ago  the  patient  had  sexual  intercourse  with  a  pros- 
titute, and  about  one  week  later  he  saw  a  small  blister 
one-fourth  of  an  inch  in  diameter  at  the  base  of  his 
penis.  This  blister  remained  of  apparently  the  same 
size  for  the  next  ten  days,  when  he  again  had  sexual  in- 
tercourse, and  a  few  days  after  the  last  exposure,  the 
sore  upon  the  base  of  the  penis  began  to  enlarge  and 
became  painful,  and  it  had  been  steadily  extending  up 
to  the  time  of  admission  to  the  hospital.  The  sore  has 
been  painful,  and  during  the  week  prior  to  admission 
prevented  sleep.  He  had  had  a  bubo  on  the  right  side, 
that  had  been  painted  with  iodine  which  reduced  its  size 
somewhat,  and  rendered  it  less  painful  than  it  was  at  first. 
The  sore  upon  the  penis  had  been  treated  with  iodoform 
and  charcoal  poultices. 

The  patient's  general  health  has  been  good,  no  cough, 
feet  never  swollen,  no  rheumatism.  On  admission, 
there  was  found  a  large  non-suppurating  bubo  in  the 
right  groin,  and  a  sore  with  indurated  edges  at  the  base 
of  the  penis  on  the  right  side.  The  sore  was  triangular 
in  shape  with  the  apex  extending  up  the  penis,  one  angle 
at  the  base  running  into  the  scrotum,  and  the  other  into 
the  groin.  The  sore  measured  about  one  inch  on  each 
side,  and  was  deeply  excavated,  measuring  more  than  an 
inch  in  depth,  and  it  had  a  sloughy  base. 

A  papular  and  pustular  eruption  was  scattered  thickly 
over  the  face,  trunk,  and  extremities.  The  inguinal, 
epitrochlear,  and  cervical  glands  were  enlarged.  There 
had  been  a  small  ulceration  upon  the  dorsum  of  the 
tongue,  which  lasted  about  two  days. 

The  patient's  general  condition  was  good  ;  his  bowels 
were  regular ;  there  was  no  urinary  trouble  ;  his  tongue 
was  coated ;  his  mouth  dark  red ;  and  his  temperature 
102.2"*  F. 

July  15th. — The  cavity  of  the  sore  was  swabbed  out 
with  deliquesced  chloride  of  zinc,  and  packed  with  iodo- 
form gauze. 

July  23d. — There  was  still  some  phagedena  at  the 
angles  of  the  sore,  which  was  touched  with  chloride  of 
zinc  I  to  4,  and  dressed  with  iodoform. 

July  31st. — The  eruption  had  gradually  increased  in 
size,  and  now  many  of  the  pustules  measure  three-fourths 
of  an  inch  in  diameter,  and  are  covered  with  scabs  raised 
half  an  inch  in  circumference,  domed  and  black,  and  sur- 
rounded by  a  reddish  areola. 

August  7  th. — Ulcer  now  level  with  the  surface  and 
looks  well.  The  patient  takes  protiodide  oi  mercury 
gr.  j.  t.Ld. 

August  8th. — Ordered  inunctions,  ung.  hydrarg.,  3ss. 
every  night. 

September  4th. — Scabs  have  nearly  all  fallen,  leaving 
ulcers  which  are  rapidly  healing. 

Dr.  Wyeth  remarked  that  the  case  had  shown  pha- 
gedena to  a  degree  he  had  not  seen  before  with  an  acute 
syphilide.  There  was  no  evidence  of  tertiary  lesion. 
He  regarded  the  case  as  one  of  acute  phagedenic  pus- 
tular syphilide,  and  maintained  that  it  illustrated  the 
statement  of  Bumstead  and  Taylor  that  a  pustular  syphi- 
litic eruption  is  apt  to  follow  a  phagedenic  syphilitic 
ulcer  on  the  penis,  and  the  violence  is  frequently  propor- 
tionate to  the  violence  of  the  initial  lesion. 

A  point  of  interest  in  the  treatment  was  the  fact  that 
very  large  doses  protiodide  of  mercury  were  given  daily 
for  three  or  four  weeks  before  the  sores  began  to  hea^ 
and  no  unpleasant  constitutional  effects  belonging  to  the 
drug  were  produced. 

Dr.  Van  Gieson  asked  if  self-inoculation  was  ruled 
out  entirely. 


442 


THE   MEDICAL  RECORD. 


[October  i8,  1884, 


Dr.  Wyeth  replied  that  it  was  not  absolutely,  although 
he  was  unable  from  the  clinical  history  to  ascertain  its 
existence. 

Dr.  Van  Gieson  had  seen  a  similar  case,  in  which 
there  was  a  mixed  sore,  because  there  was  a  history  of 
two  intercourses.  He  regarded  it  as  extremely  difficult 
to  draw  the  border  line  in  cases  of  that  kind. 

Dr.  Wybth  had  recognized  the  difficulties  attending  a 
complete  diagnosis,  and  had  also  been  convinced,  the 
more  he  studied  the  disease,  of  the  great  variety  of  the 
manifestations  of  syphilis. 

Dr.  Levi  referred  to  what  Mr.  Jonathan  Hutchinson 
had  called  syphilitic  lupus,  and  had  seen  three  cases,  of 
which  he  had  been  reminded  by  the  case  presented  by 
Dr.  Wyeth.  He  further  remarked  that  in  Vienna  syphilis 
was  diagnosticated  by  the  disease  attacking  the  root  of 
the  nose,  while  lupus  attacks  the  apex  of  the  nose. 

Dr«  Wyeth  remarked  that  in  his  case  the  disease  at- 
tacked not  only  the  nose  at  the  apex,  but  other  portions 
of  the  body,  and  was  seen  upon  the  forehead,  etc.  He 
regarded  the  lesion  upon  the  apex  of  the  nose  as  due  to 
strangulation  of  the  vessels. 

Dr.  Levi  remarked  that  he  did  not  doubt  the  correct- 
ness of  the  diagnosis  in  Dr.  Wyeth's  case,  and  merelv 
mentioned  the  point  made  by  Mr.  Hutchinson  that  syphi- 
lis was  one  of  the  causes  of  lupus,  of  which  he  had  seen 
cases  which  had  a  striking  resemblance  to  the  one  pre- 
sented. 

Dr.  Van  Gieson  asked  if,  when  the  initial  lesion  was 
pure  chancre,  extensive  destruction  of  tissues  at  the  seat 
of  the  lesion  was  to  be  expected  in  ordinary  cases  ? 

Dr.  Wyeth  said  no :  that  true  chancre  was  not  apt  to 
be  ulcerative,  but  there  are  forms  which  are  chancroid  in 
type. 

Dr.  Van  Gieson  referred  to  one  case  of  syphilis  under 
his  care,  which  resisted  all  forms  of  treatment.  The  case 
was  also  treated  by  Dr.  Bumstead,  but  without  effect,  and 
he  (Dr.  Bumstead)  regarded  it  as  one  of  the  cases  in 
which  the  poisoning  is  so  profound  that  it  could  not  be 
reached  by  ordinary  remedies.  The  beginning  of  the 
case  was  very  much  like  that  of  the  one  presented  by 
Dr.  Wyeth.  The  initial  lesion  was  upon  one  labium, 
which  sloughed  away  entirely  and  very  rapidly,  and  be- 
fore the  disease  could  be  arrested  the  opposite  labium 
was  involved  and  also  completely  destroyed.  The  sec- 
ondary symptoms  were  of  the  most  obstinate  character, 
were  followed  by  iritis  and  the  later  eruptions,  despite 
the  most  active  mercurial  treatment.  The  rodent  variety, 
therefore,  might  be  seen  early  in  the  history  of  a  case. 

Dr.  Wyeth  thought  that  such  cases  were  not  so  rare 
as  they  might  appear  to  be.  Some  cases  of  syphilis  re- 
sist all  forms  of  treatment  and  go  on  to  a  fatal  termina- 
tion without  abatement  of  the  disease.  In  other  cases 
the  patients  live  for  years  without  the  recurrence  of 
symptoms,  after  having  been  under  treatment.  He  re- 
garded syphilis  as  a  curable  disease  and  not  a  difficult 
disease  (o  cure.  At  all  events  he  preferred  to  take  his 
risks  with  syphilis  rather  than  typhoid  fever  or  pneu* 
monia.  He  also  believed  that  thousands  of  cases  of 
syphilis  had  recovered  without  medicine  which  produced 
any  direct  effect  upon  the  poison  of  the  disease. 

Dr.  Van  Gieson  remarked  that  the  point  to  which  he 
wished  to  make  special  reference  was  the  early  appear- 
ance of  the  phagedena.  He  had  had  a  patient  under 
observation  who  was  treated  for  syphilis  ten  years  ago, 
and  it  was  supposed  that  he  was  cured,  but  at  present  he 
was  suffering  from  paralysis  of  the  abducens  believed  to 
be  of  syphilitic  origin,  without  having  contracted  the  dis- 
ecue  a  second  time. 

Dr.  Seguin  remarked  that  nerve  phenomena  of  a 
syphilitic  character  might  develop  as  long  as  twenty-five 
years  after  the  disappearance  of  all  symptoms  of  the  first 
attack,  and  this  also  in  cases  in  which  the  primary  syphil- 
itic attack  was  mild. 

The  President  referred  to  cases  in  which  syphilitic 
lesions  developed  twenty  years  after  the  primary  attack, 


and  the  patients  had  been  reasonably  well  treated  at  first. 

Dr.  Wyeth  remarked  that  in  many  cases  syphilis  re- 
mained dormant  in  the  system  for  twenty  or  thirty  years, 
and  then  tertiary  symptoms  developed, 

Dr.  Levi  remarked  that  the  fact  that  the  initial  lesion 
in  Dr.  Wyeth*8  case  was  pustular  made  him  believe  that 
the  general  system  of  the  patient  was  affected  by  some^ 
thing  besides  syphilis.  With  regard  to  treatment,  when- 
ever mercury  had  failed  to  control  the  disease,  it  had 
frequently  occurred  that  to  stop  all  specific  remedies  and 
resort  to  hygienic  measures  with  cod-liver  oil  and  iron 
was  the  very  best  method  of  treatment  which  could  be 
adopted. 

The  President  had  often  adopted  this  plan,  and  had 
even  be^n  the  use  of  cod-liver  oil,  iron,  eta,  before  ad- 
ministering mercurials. 

The  Society  then  went  into  executive  session. 


OUR  PARIS  LETTER. 

(From  our  Own  Cotropondcnt) 

THE    PROPOSED    AMBULANCE    SYSTEM    IN    PARIS    AND  DR. 
NACHTEL — ^THE    REPORT  OF  THE   CHOLERA   EPIDEMIC 

Pakis,  September  tfi,  1884. 

The  readers  of  The  Record  may  recollect  that  so  far 
back  as  the  year  1880  Dr.  Nachtel  submitted  a  proposal 
to  the  Academy  of  Medicine  and  to  the  Municipal 
Council  of  Paris  for  the  introduction  of  ambulance  car- 
riages to  meet  the  requirements  of  this  populous  city  in 
case  of  street  accidents,  as  at  present  nothing  of  the  kind 
exists.  He  even  offered  his  services  gratuitously  to  assist 
in  the  organization  of  a  system  similar  to  what  has  been 
so  long  m  o])eration  in  New  York,  and  which  has  ren- 
dered such  signal  service.  Dr.  NachteFs  plans  were 
highly  approved  of  and  accepted  in  principle,  but,  how- 
ever incredible  it  may  seem,  nothing^  has  as  yet  been 
decided  upon.  There  has  been  no  lack  of  perseverance 
on  the  part  of  Dr.  Nachtel,  for  he  has  been  unremitting 
in  his  endeavors,  and  he  has  not  left  a  stone  unturned  to 
have  his  scheme  carried  out.  He  has  paid  personal 
visits  to  officials  whom  he  thought  in  a  position  to  help 
him  in  the  matter,  from  the  Prefect  of  Police  to  the 
President  of  the  Republic,  by  whom  he  was  received  with 
the  usual  French  politeness,  but  the  affair  is  not  a  whit 
more  advanced  than  it  was  four  years  ago.  Finding  little 
hope  from  official  quarters,  Dr.  Nachtel  has,  from  time 
to  time,  appealed  to  the  public  through  the  medical  and 
lay  press,  but  without  any  better  result.  He  has  now 
published  a  pamphlet  in  which  he  has  taken  the  pains  to 
recall  the  different  phases  through  which  the  subject  has 
passed  since  1880,  and  to  reproduce  the  various  docu- 
ments he  has  officially  submitted  to  the  Academy  OC 
Medicine,  to  the  Council  of  Hygiene,  and  to  the  Muni- 
cipal Council  of  Paris,  and  once  more  makes  an  appeal 
to  all  whom  it  may  concern  (and  surely  it  concerns 
everybody  residing  in  this  city  or  only  passing  through) 
to  have  Dr.  NachteVs  scheme  realized  without  further 
delay,  as  street  accidents  are  as  rife  as  ever  and  the  ex- 
isting arrangements  are  quite  inadequate  to  meet  them. 
The  following  statistical  report  just  published  by  the 
Prefect  of  Police  will  show  the  necessity  for  having  am- 
bulance carriages  at  the  disposal  of  the  population.  The 
report  relates  to  accidents  in  Paris  and  in  the  suburbs 
during  the  year  1883.  The  total  number  of  accidents 
during  the  year  was  759.  Of  this  number  there  were  20S 
cases  of  wounds  of  the  head  and  192  cases  of  drowning; 
there  were  212  cases  of  wounds  produced  by  various 
causes,  59  cases  of  illness  of  various  kinds,  and  31  cases  of 
epilepsy ;  182  persons  received  medical  aid  in  the  eight 
pavilions  established  along  the  banks  of  the  Seine  and  of 
the  canals  in  Paris  for  succoring  the  drowned. 
To  giv^  strength  to  his  cause,  Dr.  Nachtel  has  even 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


443 


secured  the  support  of  Victor  Hugo,  whose  voice  he 
thought,  from  his  high  standing  in  the  favor  of  the  nation, 
irbuld  attract  some  notice.  The  idea  was  as  far-fetched 
as  it  was  a  happy  one,  as  Victor  Hugo  is  not  only  a  great 
poet  but  he  is  also  a  great  philanthrophist,  and  in  the 
latter  capacity  he  expressed  himself  as  follows  :  **  New 
York  has  commenced,  Paris  will  continue  that  which  you 
propose,  and  which  is  suggested  by  reason  and  by  evi- 
dence. The  success  of  the  scheme  will  confirm  your  af- 
firmations ;  it  is  clear,  it  is  definite,  it  is  humane.  I  ap- 
prove of  it  and  congratulate  you."  The  above  is  a  trans- 
lation of  Victor  Hugo's  autograph  letter  to  Dr.  Nachtel, 
which  has  been  reproduced  in  the  pamphlet  above  re- 
ferred to,  but  I  am  afraid  the  French  will  pay  no  more 
heed  to  it  than  they  would  to  any  of  the  great  poet's 
poetical  effusions. 

The  French  are  a  peculiar  people,  they  are  quick  in 
some  things  and  deplorably  slow  in  others.  And  one  of 
the  things  they  are  slow  in  is  the  adoption  of  any  innova- 
tion coming  from  a  foreigner.  Moreover,  they  are  so 
tied  down  by  red-tapeism  that,  even  in  the  management 
of  their  internal  affairs,  when  a  proposition  is  made  by 
one  of  their  own  for  the  public  good,  the  course  it  has  to 
go  through  before  it  is  sanctioned  or  pronounced  upon  is 
so  interminable  and  attended  with  such  vexatious  pro- 
cesses that  in  many  cases  the  proposition  is  either  for- 
gotten or  hopelessly  abandoned.  In  this  assertion  I  am 
Supported  by  an  editorial  in  a  recent  number  of  the  Pro- 
gris  Medical^  in  which  the  writer,  with  reference  to  this 
very  question  of  ambulance  carriages  as  proposed  by  Dr. 
Nachtel,  states  :  "  Unfortunately  everything  is  done  very 
slowly  in  France,  and  practical  questions  are  long  since 
resolved  by  our  friends,  the  Anglo-Saxons,  before  they  are 
even  broached  by  us.  In  spite  of  our  superficial  love  for 
novelty,  we  are,  at  the  bottom,  great  followers  of  routine, 
and  we  bear  with  astonishing  patience  all  the  defects 
of  ao  administration  for  which  Europe  has  never  envied 
OS."  I  have  translated  the  original  paragraph  as  literally 
as  possible,  in  order  that  I  may  not  be  accused  of  undue 
exaggeration,  although  it  is  hardly  necessary  to  offer 
any  apology,  as  what  is  stated  above  is  a  proverbial  fact. 
I  consider  it  highly  discreditable  to  the  country,  the  in- 
habitants of  which  assume  to  be  in  the  van  of  progress 
and  civilization,  to  be  so  exclusive  and  so  adverse  to 
foreign  intervention,  even  when  it  affects  their  nearest 
interests,  for  while  the  scheme  above  referred  to  is  long 
since  in  operation  in  London  and  in  many  other  manu- 
facturing towns  in  England  and  Scotland,  Paris  is  still 
without  its  anabulance  service. 

I  may  here  recall  another  instance  of  French  repug- 
nance to  foreign  innovations.  It  so  happens  that  Dr. 
Nachtel  is  here  again  the  instigator.  I  refer  to  the 
necessity  of  adopting  some  system  to  prevent  people  be- 
ing run  over  by  cabs  and  other  vehicles  moving  about 
\^  the  city  of  Paris.  More  than  a  year  ago  the  subject  was 
brought  to  the  notice  of  the  Prefect  of  Police  and  a  plan 
was  submitted  to  that  functionary  for  carrying  out  this 
veiy  desirable  and  philanthropic  object,  but  nothing  has 
been  heard  of  it  since.  The  consequence^ is  people  are 
still  being  run  over  and  the  victims  are  left  to  the  tender 
mercies  of  the  public,  as  no  particular  arrangements  are 
made  for  attending  to  them.  It  is  true  that  refuges  in 
the  streets  have  been  multiplied,  but  they  are  few  and 
far  between  and  are  often  not  to  be  found  where  they  are 
most  required.  The  plan  suggested  was  that  adopted  in 
London  and  New  York,  but  I  have  it  on  good  authority 
that  the  Paris  policemen  have  received  no  particular 
orders  to  interfere  with  the  vehicles  going  to  and  fro,  or 
to  render  assistance  to  pedestrians  in  the  streets  unless 
they  were  moved  to  do  so  by  their  own  sense  of  courtesy 
or  humanity. 

Dr.  Proust,  Inspector-General  of  the  Sanitary  Services 
in  France,  has  just  sent  in  his  official  report  to  the  Min- 
ister of  Commerce  on  the  state  of  the  cholera  epidemic. 
The  report  was  published  in  the  Journal  Officiel  in  which 
he  states  that  the  epidemic  is  evidently  on  the  decline, 


thanks  to  the  energetic  measures  that  have  been  taken 
to  ensure  salubrity  in  the  dwellings,  as  wdl  as  in  the 
streets.  The  progress  of  the  present  epidemic  in  France 
and  Italy  demonstrates  once  more  the  futility  and  even 
the  danger  of  "cordons  sanitaires"  and  the  necessity  for 
the  rigorous  application  of  hygienic  measures. 


OUR  LONDON  LETTER. 

(From  our  Special  ConrespondenL) 

BUYING  PRACTICES — MEDICAL  AGENTS  —  BACILLI  AND 
THEIR  DISCOVERIES — ^THE  ADVANCE  IN  ANTISEPTICS — 
THE   ANn-VACCINATION   CRAZE. 

London,  September  29,  1884. 

The  holiday  season  is  now  fairly  over,  and  so  is  the  fine 
weather.  Most  practitioners  are  now  reassuming  harness 
for  the  winter.  Among  general  practitioners  many  are 
now  departing  to  fresh  localities,  having  sold  their  prac- 
tices and  either  purchased  new  ones  or  gone  elsewhere 
to  start.  Practices  are  changing  hands  at  all  seasons  of 
the  year,  but  the  summer  and  autumn  perhaps  witness 
more  changes  than  the  other  seasons  do.  The  most 
usual  mode  of  commencing  general  practice  is — among 
those  possessed  of  sufficient  capital  to  do  so — to  pur- 
chase one.  The  prices  given  vary  a  good  deal  with 
the  class  of  practice  acquired,  but  many  fairly  good- 
class  general  practices  can  be  bought  for  a  sum  equal  to 
the  total  receipts  for  twelve  or  eighteen  months.  The 
incomer  has,  of  course,  to  support  himself  during  the  first 
year  until  his  first  bills  have  been  paid.  In  good-class 
practices  little  ready  money  is  taken.  Medical  agents 
are  accustomed  to  gauge  the  character  of  a  practice  by 
the  amount  of  ready  money  taken,  ue.y  the  more  ready 
money  taken  the  lower  is  usually  the  class  of  practice. 
Christmas  bills,  too,  are  often  not  paid  until  February  or 
March.  The  purchaser  of  a  practice  has  usually  to  take 
the  lease  of  the  house  where  the  latter  is  lesisehold, 
and  is  often  required  to  purchase  the  furniture  at  a  valu- 
ation. During  the  period  of  introduction  he  has  to  divide 
the  returns  with  his  predecessor.  Bearing  all  this  in  mind 
it  will  be  seen  that  to  purchase  a  practice  of  eight  hun- 
dred pounds  a  year  requires  a  capital  of  nearly  two  thou- 
sand pounds. 

Partnerships  are  much  more  expensive  than  ordinary 
practices,  as  the  income  is  more  certain  and  is  sometimes 
guaranteed.  Two  years'  purchase  is  a  minimuna  price, 
and  often  much  more  is  asked.  Practices  in  fashionable 
resorts  fetch  more  than  ordinary  practices.  Consulting 
practices  are  rarely  to  be  purchased,  but  occasionally  such 
is  the  case.  I  have  known  several  instances  of  special 
practices  changing  hands,  and  for  very  large  sums.  The 
practice  of  a  general  physician  or  surgeon  is  very  rarely 
to  be  obtained  thus  though,  and  still  more  rarely  kept  if 
purchased,  being  so  largely  personal. 

Most  transfers  of  practices  take  place  through  medical 
agents,  who  charge  a  commission  to  venders,  but  none  to 
purchasers  or  those  seeking  information.  Many  medical 
agents  are  either  medical  men  themselves  or  related  to 
medical  men.  From  the  number  of  them  in  London  it 
would  appear  to  be  a  good  business.  I  have  often  been 
surprised  to  see  so  few  practices  advertised  for  sale  in 
American  medical  journals.  The  agents'  advertisements 
often  occupy  six  or  eight  pages  of  our  medical  weekly 
journals.  The  Lancet^  perhaps,  has  the  largest  number 
of  this  class  of  advertisements,  being  the  oldest  medical 
paper,  but  the  other  journals  now  have  a  fair  share. 

The  bacillar  origin  of  cholera  still  attracts  a  large 
share  of  attention.  I  do  not  think  the  profession  here 
though  are  yet  at  all  inclined  to  accept  unquestioningly 
Koch's  views  on  the  comma-bacillus  and  its  significance^ 
Bacilli  have  been  rather  overdone  of  late  years,  and  so 
many  paragraphs  have  appeared  in  the  journals  attribut- 
ing this  disease  and  the  other  disease  to  bacilli,  that 
sound  physicians  are  getting  rather  incredulous  as  to 
some  of  the  discoveries  made  by  means  of  immersion  ob- 


444 


THE   MEDICAL  RECORD. 


[October  i8,  1884. 


jectives.  It  is  not  many  years  since  Professor  Klein  had 
to  recant  some  apparent  discoveries  he  had  made,  and 
acknovrledge  that  the  appearances  he  had  described 
were  in  reality  due  to  the  method  of  preparation  and  the 
reagents  employed.  I  must  give  him  credit  for  honestly 
acknowledging  his  error. 

There  can  be  no  doubt  that  recent  studies  on  micro- 
organisms and  their  relation  to  disease  have  immensely 
stimulated  the  use  of  antiseptics,  and  this,  too,  among 
many  who  by  no  means  give  in  their  allegiance  to  the 
germ  theories.  Carbolized  vaseline  has  to  a  large  ex* 
tent  replaced  the  time-honored  lard  in  obstetric  practice, 
and  carbolic  lotion  is  largely  used  in  out-patient  prac- 
tice, even  by  surgeons  who  would  never  think  of  using 
the  spray,  and  many  of  whom  never  performed  opera- 
tions antiseptically. 

The  anti-vaccination  movement  at  Leicester  is  assum- 
ing serious  proportions.  Leicester  has  long  been  a  cen- 
tre of  the  agitation  against  vaccination,  and  for  many 
years  returned  to  Parliament  a  gentleman  of  very  pro- 
nounced anti-vaccination  views — Mr.  Peter  Taylor. 
Leicester  is  by  no  means  an  average  town  in  this  respect. 
In  most  parts  of  Great  Britain  there  is  practically  no 
great  difficulty  in  getting  the  vaccination  acts  carried  out 
It  is  very  common  for  the  mothers  of  infants  about  to  be 
vaccinated  to  express  an  objection  to  it,  on  the  score  of 
the  pain  inflicted,  and  even  to  say  they  should  not  have 
their  children  done  if  they  were  not  obliged  to  by  law, 
but  most  of  them  are  quite  ready  to  acknowledge  the  de- 
sirability of  having  it  done,  even  while  expressing  a  sen- 
timental objection  to  it.  The  rigid  opposition  of  the 
fervid  anti- vaccinationist  is  of  a  very  different  type.  For- 
tunately such  are  not  very  numerous  in  ordinary  English 
towns.  They  form  a  very  small  minority  of  the  popula- 
tion, and  a  decreasing  one.  Most  Englishmen  have  a 
good  deal  of  reverence  for  law,  and  I  believe  the  anti- 
vaccination  movement  would  long  since  have  died  out 
but  for  a  few  fanatics  who  fanned  the  flame  of  discontent 
I  must  say  that  when  a  batch  of  anti-vaccinationists  are 
committed  to  prison  for  obstinate  refusal  to  comply  with 
the  law,  their  voluntary  martyrdom  excites  a  good  deal 
of  sympathy  even  among  those  who  differ  from  them  in 
opinion,  and  probably  does  more  than  any  amount  of 
agitation  to  advance  their  cause  among  the  populace  at 
large.  There  is  also  an  increasing  feeling  against  fining 
the  same  parents  over  and  over  again.  «•  Liberty  of  the 
subject "  has  always  been  a  popular  cry  in  England. 


"DEAD  TEETH    IN  THE  JAWS." 

To  THB  Editok  or  The  Medical  Recobix 

Sir:  In  the  editorial  of  this  date,  entitled  "Dead 
Teeth  in  the  Jaws,"  your  suggestions  as  to  the  desirabil- 
ity of  medical  men  being  "  better  informed  concerning 
diseases  of  the  jaws  and  mouth,"  strike  a  dentist  as 
quiie  d  propos ;  for  the  public  good,  physicians  should 
be  better  able  to  discriminate  between  "  numerous  harm- 
ful dental  appliances"  and  modes  of  practice  and  the 
legitimate  conservative  treatment  of  diseased  teeth, 
which  is  based  on  accurate  knowledge  of  the  anatomy 
and  physiology  of  the  maxillary  tissues  and  their  ap- 
pendages. You  do  not  overestimate  the  importance  of 
instruction  in  oral  surgery  in  the  medical  schools.  But 
while  the  medical  profession  is  happily  beginning  to 
realize  the  importance  of  teeth,  as  factors  m  nervous 
and  nutritional  disturbances,  they  should  not  lose  sight 
of  the  value  of  teeth,  nor  of  the  possibilities  of  treat- 
ment 

'*  Dead  teeth,*'  so  called,  are  not  in  an  appreciable 
degree  deprived  of  periosteal  nourishment  by  the  death 
of  the  pulp,  which  occupies  the  central  canal  of  the 
root,  and  maintains  the  vitality  of  the  dentine  ;  the  pe- 
ripheral tissue  of  the  root — cementum,  histological! v 
analogous  to  bone — may  still  be  nourished  in  a  practi- 
cally normal  condition  by  the  periosteum  through  a  life- 


time, provided  the  latter  tissue  is  not  permitted  to  suffer 
from  irritation,  which  is  liable  to  be  produced  by  the 
mephitic  products  of  putrefaction  of  the  dead  pulp  tis- 
fue,  escaping  through  the  apical  foramen  of  the  root 
Inflammation  and  abscess  as  well  as  the  more  obscure 
reflex  phenomena,  when  associated  with  pulpless  teeth, 
almost  invariably  have  the  apical  foramen  and  the  peri- 
osteum about  it  for  a  starting-point ;  to  render  this  point 
and  the  root-canal  aseptic  and  preserve  them  in  that 
condition  by  thoroughly  filling  the  canal  with  impervious 
material,  which  shall  prevent  the  entrance  through  the 
foramen  of  tissue  fluids  which  would  in  turn  become  an 
irritant,  is  the  aim  of  all  intelligent  treatment ;  and  when 
performed  with  the  skill  and  thoroughness  demanded, 
these  operations  rarely  fail  to  place  the  root  in  a  per- 
fectly  benign  condition.  Want  of  knowledge,  skill,  or 
conscience  on  the  part  of  dentists,  unfortunately,  causes 
too  many  of  these  operations  to  be  harmful  and  often 
disastrous ;  but  when  the  medical  profession  have  given 
the  attention  to  this  subject  that  its  importance  de- 
mands, it  will  be  able  to  do  much  more  toward  correct- 
ing the  evil.  Dr.  Sexton  has  rendered  a  notable  service 
to  the  profession,  and  to  humanity,  in  making  known 
the  results  of  his  careful  observations  of  diseased  teeth 
which,  through  neglect  or  **  ill-advised  dentistry,"  have 
become  the  cause  of  serious  aural  disturbances.  ^ 

It  is  to  be  hoped  that  his  valuable  contribution  and 
the  editorial  on  the  subject  will  further  stimulate  interest 
in  this  subject.  J.  Morgan  Howe,  M.D.S.,  M.D. 

New  York,  October  4,  1884. 


To  THE  Editor  or  Tkb  Mbdical  Rbcoko. 

Sir  :  Lately  Dr.  Sexton  has  given  to  the  profession  a 
number  of  articles  describing  the  relation  between  den- 
tal and  aural  troubles.  These  articles  were  interesting 
and  conclusive  ;  but  the  last  article,  in  The  Record  of 
October  4th,  includes  a  series  of  cases,  the  results  of 
which,  in  several  instances,  are  not  at  all  conclusive. 
Although  Dr.  Sexton  is  to  be  congratulated  in  bringing 
forward  this  new  line  of  thought,  it  must  not  be  forgotten 
that  this  conjunction  of  neuralgias  is  exceedingly  rare. 

That  poor  people  have  bad  teeth  and  much  wax  in 
the  ears  is  the  rule  and  not  the  exception ;  the  teeth  are 
allowed  to  decay  from  inability  to  pay  a  dentist ;  and 
the  ears  are  not  cleaned  through  inadvertency.  This 
conjuncture  of  circumstances  may  frequently  obtain  with- 
out there  being  a  connected  correlation  of  symptoms  in 
the  two  organs. 

Dr.  Sexton  did  not  state,  for  the  benefit  of  his  read- 
ers, that  it  is  only  the  middle,  constricted,  portion  of  the 
auditory  canal  that  secretes  cerumen  nominally;  the 
third,  innermost,  portion  of  the  tube  secretes  cerumen 
only  under  pathological  conditions ;  this  might  aid  in 
the  diagnosis. 

Regarding  Dr.  Sexton's  remarks  on  the  prevailing 
practice  of  treating  teeth,  instead  of  extraction,  we  think 
these  remarks  are  too  sweeping,  and  thereby  calculated 
to  mislead  a  great  many  medical  practitioners  who  have 
paid  no  attention  to  dentistry,  or  have  even  endeavored 
to  acquire  a  theoretical  knowledge  of  the  dental  organs. 
There  is  a  good  deal  of  imperfect  work  turned  out  by 
both  classes  of  dentists,  the  cheaper  and  the  more  ex- 
pensive ones  ;  even  extraction  is  often  clumsily  and  im- 
perfectly done  ;  but  all  this,  which  is  to  be  deplored, 
does  not  negative  the  fact  that,  with  the  exception  of 
certain  conditions  (well  known  and  rapidly  diagnosed  by 
the  practised  hand),  it  is  far  preferable  to  leave  the  teeth 
in  the  jaw,  having  the  carious  portion  removed,  than  to 
cap,  fill,  build,  or  crown.  There  are  several  objections 
to  extraction  ;  the  chief  one,  not  generally  appreciated, 
is  that  the  corresponding  tooth  in  the  other  jaw  has  now 
no  opposing  tooth  for  the  purpose  of  mastication. 

Dr.  Sexton's  remark  on  wearing  dental  plates  is  9^ 
posile ;  besides  the  danger  of  swallowing  the  teeth,  or 
plate  even  (in  some  instances  having  caused  instant 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


445 


death),  the  pressure  of  the  plate  causes  absorption  of  the 
palatal  membrane  and  exfoliation  of  the  palatine  process 
of  the  superior  maxillajy  bone  in  some  cases ;  where  mer- 
cury is  used  in  preparing  the  cheap,  rubber  plates,  there 
is  danger  of  salivation,  with  possibly  detrimentail  local 
results. 

Dr.  Sexton's  remarks,  that  dentists  leave  dead  teeth  in, 
which  should  be  extracted,  are  apt  to  lead  the  inexpe- 
rienced practitioner  to  recommend  a  wholesale  extraction 
of  carious  teeth,  to  the  great  detriment  of  the  individual. 
It  is  an  undoubted  fact  that  dentistry  has  made  great 
strides,  thereby  greatly  benefiting  the  public.  It  is  now 
no  longer  necessary  to  kill  a  nerve  before  filling,  neither 
is  it  necessary  to  retain  the  nerve,  as  life  and  nutrition 
can  be  carried  on  through  the  peridental  membrane,  mi- 
croscopy demonstrating  the  continuity  of  vessels  through 
that  membrane  into  the  superfices  of  the  fangs  ;  lastly, 
bridging  and  crowning  do  away  with  plates. 
Respectfully, 

C.  E.  Nelson,  M.D. 


Nbw  Youc. 


To  THK  Editor  or  The  Mbdical  Recoko/ 

Sir  :  In  The  Medical  Record  of  October  4,  1884,  ap- 
peared an  editorial  upon  "Dead  Teeth  in  the  Jaws,"  in 
which  the  practice  of  retaining  dead  or  diseased  teeth  in 
the  mouth  is  condemned.  Reference  is  also  made  to 
the  <*  Clinical  Notes  on  Aural  Diseases,"  to  be  found  in 
another  part  of  the  same  number  of  The  Record,  and 
in  which  Dr.  Sexton  is  reported  as  also  condemning  the 
practice  *and  charging  dentists  with  doing  more  harm 
than  good  by  their  methods  of  treatment.  He  says: 
"  Since  dentistry  has  become  such  a  popular  business, 
and  dead  and  diseased  teeth  have  been  so  carefully  re- 
tained in  the  jaws  through  their  influence,  especially 
among  the  better-to-do,  nervous  diseases  about  the  head 
are  becoming  alarmingly  common.  The  very  general 
custom  of  wearing  false  teeth  in  the  mouth  attached  to 
vulcanite,  rubber,  celluloid,  and  other  plates  is  also  an 
evil  of  vast  proportions.  Indeed,  I  sometimes  think 
that  the  evil  done  through  ill-advised  dentistry  is  greater 
than  the  possible  good  arising  from  the  work  of  the  more 
capable  dendsts." 

These  are  very  sweeping  statements,  and  I  am  sure 
that  upon  a  more  careful  investigation  they  cannot  be  sub- 
stantiated by  facts.  The  question  to  determine  is,  What 
is  iU-advised  dentistry  ?  In  the  minds  of  some  medical 
men,  it  would  seem  to  be  the  attempt  at  restoring  dead 
(pulseless)  or  diseased  teeth  to  a  healthy  condition,  and 
that  extraction  of  such  teeth  was  the  only  safe  practice. 
Now,  against  such  teaching  I  raise  an  earnest  protest 
The  cases  in  which  trouble  arises  from  the  retention  of 
dead  and  diseased  teeth  which  have  been  treated  by  the 
average  dentist,  or  from  the  wearing  of  artificial  teeth, 
most  be  very  small  indeed  in  proportion  to  the  number 
treated  or  wearing  such  appliances.  The  cause  lies 
more  in  the  neglect  of  dental  treatment  than  in  the  re- 
sult of  it,  as  evidenced  by  Dr.  Sexton's  own  cases.  That 
much  harm  is  done  by  ignorant  dentists — and  they  are  not 
a  few — there  is  abundant  proof;  but  that  this  harm  out- 
weighs the  good  done  by  the  better  class  of  dentists — 
who  are  also  not  a  few— certainly  cannot  be. possible. 
Few  specialists  succeed  better  in  the  treatment  of  dis- 
ease  than  the  better  class  of  dentists,  and  it  is  their 
duty  to  remove  an  offending  tooth  when  necessary ;  but 
their  highest  duty  is  to  save  it  if  possible. 

The  extraction  of  a  tooth  simply  because  it  is  pulp- 
less,  the  cause  of  an  abscess,  badly  decayed,  encrusted 
with  tartar,  the  seat  of  pericemental  inflammation,  or 
pyorrhoea  alveolaris,  etc,  would  be  a  sin  against  good 
practice;  for  all  such  conditions  are  in  a  majority  of 
cases  amenable  to  treatment,  and  should  no  more  be 
sacrificed  on  account  of  their  condidon  than  that  an  eye 
should  be  enucleated  because  it  was  affected  with  con- 
junctivitis or  ulceration  of  the  cornea,  or  that  a  bone 


should  be  resected  because  at  one  point  it  was  affected 
with  caries  or  necrosis,  or  a  leg  or  arm  amputated  be- 
cause it  was  the  seat  of  some  disease  which  had  occa^ 
sionally  resisted  intelligent  treatment  The  duty  of  the 
ophthalmologist,  of  the  surgeon,  and  of  the  dentist  alike 
is  to  save  the  organs  upon  which  they  operate,  and  not 
to  sacrifice  them.  The  latter  procedure  would  be  many 
times  less  troublesome  to  the  operator  and  the  shortest 
way  out  of  the  difficulty  for  the  patient ;  but  it  would  not 
be  based  upon  sound  surgical  principles,  it  would  not 
be  common  sense,  nor  would  it  be  right 

To  the  minds  of  many  people^the  teeth  are  of  but 
little  consequence,  and  I  am  sorry  to  say  their  value  is 
not  properly  appreciated  by  many  physicians,  if  one  may 
judge  from  the  advice  often  given  to  their  patients,  viz., 
"  It  a  tooth  troubles  you,  have  it  extracted  ; "  and  with 
equal  propriety  they  might  say,  if  your  eye  troubles  you, 
have  it  taken  out — but  no  surgeon  would  be  justified  in 
doing  it,  save  as  the  last  resort. 

That  there  is  great  need  of  a  higher  educational  stand- 
ard among  dentists  is  freely  admitted.  In  fact,  it  has  been 
the  firm  conviction  for  years  of  many  in  the  profession 
that  the  dental  surgeon  should  be  regularly  educated  in 
medicine  before  taking  up  the  study  of  his  specialty ; 
that  he  should  go  through  the  same  course  of  prelimi- 
nary training  insisted  upon  by  the  specialist  in  other 
branches  of  medicine ;  and  that  the  purely  mechanical 
part  of  dentistry  (the  making  of  artificial  teeth)  as  now 
practised  should  be  divorced  from  it  and  relegated  to  the 
artisan,  thus  giving  the  dentist  opportunity  to  devote  his  en- 
tire time  to  die  study  and  practice  of  the  scientific  depart- 
ment of  his  calling.  It  is  also  a  fact  that  there  is  great 
need  that  medical  men  should  be  better  educated  in  the 
pathology  and  treatment  of  dental  and  oral  diseases,  for 
the  great  majority  are  lamentably  deficient  in  knowledge 
upon  these  subjects. 

To  this  lack  of  knowledge  may  be  attributed  the  un- 
sound advice  often  given  in  relation  to  the  diseases  of 
the  teeth  and  oral  cavity,  as  well  as  very  many  of  the  fail- 
ures to  diagnose  the  cause  of  certain  apparently  obscure 
disease's  of  the  eye  and  ear  and  neuralgias  of  the  face 
and  head,  while,  had  the  dental  surgeon  received  the 
proper  training  in  this  direction,  he  would  have  been 
able  many  times  to  determine  whether  or  not  it  was 
located  in  an  offending  tooth  or  caused  by  some  other 
oral  disease. 

The  formation  in  the  American  Medical  Association 
of  a  Section  on  Dental  and  Oral  Surgery  four  years  ago, 
and  the  more  recent  establishment  of  instruction  in  oral 
surgery  in  some  of  the  medical  colleges,  are  expressions 
by  the  representative  medical  men  of  our  country  of  the 
value  and  need  of  better  instruction  upon  these  topics, 
and  an  effort  to  supply  it 

It  is  to  be  hoped  that  the  movement  will  receive  the 
encourafirement  it  deserves. 

I  am  very  truly  yours, 

John  S.  Marshall,  M.D* 

342  Wabash  Avbnub,  Chicago,  III. 


TUBAL  PREGNANCY. 

To  THK  Editor  or  Thb  Medical  Rbcoks. 

Sir  :  Dr.  Mund6  finishes  his  article  on  his  case  of  extra- 
uterine pregnancy,  in  the  issue  for  September  27  of  this 
journal,  with  some  considerations  as  to  what  becomes 
of  the  incysted  ovum  after  the  foetus  has  been  killed  by 
electricity.  As  a  contribution  to  the  answer  to  this  ques- 
tion I  would  state  that  I  had  the  opportunity  to  examine 
the  patient  upon  whom  1  had  performed  this  operation 
in  1882  (see  "Transactions  of  the  American  Gyneco- 
logical Society,"  voL  vii.,  p,  185)  two  years  later.  She 
had  grown  considerably  stouter,  and  had  never  become 
pregnant  She  enjoyed  perfect  health,  and  the  only 
thing  she  complained  of  was  that  she  had  no  venereal 
orgasm  during  intercourse,  although  her  husband  is  a 
healthy  young  man  and  nothing  abnormal  with  regard  to 


446 


THE  MEDICAL  RECORD. 


[October  18, 1884, 


the  act  could  be  discovered  in  him.  In  spite  of  the  in- 
creased amount  of  fat  in  the  abdominal  wall,  the  pelvic 
organs  could  be  distinctly  felt  by  bimanual  palpation. 
The  uterus  was  found  anteflexed  as  at  the  time  of  the 
operation,  but  placed  in  the  median  line,  and  there  was 
no  trace  left  of  the  tumor  in  the  right  Fallopian  tube. 
Yours  truly, 

H.  J.  Garriguss,  M.D. 

168  Wbst  Twenty-thi«d  Stkbtt,  Nbw  Yokk. 


THE  REASON  WHY  ST.  LUKE'S  HOSPITAL 
DOES  NOT  FURNISH  MEDICAL  HISTO- 
RIES  TO    OUTSIDE  APPLICANTS. 

To  THE  Editos  op  Thb  Medical  Record. 

• 

Sir  :  My  attention  has  been  called  to  a  communication 
in  your  is^ue  of  this  date,  from  Dr.  Joseph  P.  Fessenden, 
of  Salem,  Mass.  It  contains  my  correspondence  with 
that  gentleman,  in  which,  on  behalf  of  this  hospital,  I 
declined  to  give  information  concerning  the  disease  with 
which  a  recent  patient  suffered  while  under  our  care. 

In  your  editorial  note  on  the  same,  you  say  that  **  it  is 
difficult  to  understand  upon  what  grounds  any  public 
hospital  can  refuse  to  give  to  a  medical  gentleman  such 
information  as  was  solicited,"  and  you  courteously  re- 
quest some  explanation  on  this  point  from  the  hospital 
authorities. 

The  answer  to  your  question  involves  the  important 
>  point  as  to  the  rights  of  patients  who  enter  our  hospitals 
for  treatment. 

Dr.  Fessenden' s  position,  as  I  understand  it,  is  that  the 
confidential  communications  which  our  patients  make  to 
our  doctors  concerning  their  own  diseases  and  the  causes 
which  led  to  them,  and  our  physicians'  diagnosis  and 
method  of  treatment  (which  are  all  matters  of  record 
in  the  Medical  History  Books  of  the  hospital),  should  in 
all  cases  be  at  the  disposal  of  any  physician  who  asks  for 
them,  as  a  guide  to  his  own  subsequent  treatment.  This 
position,  I  hold,  cannot  be  maintained. 

In  case's  of  litigation,  the  attempt  has  not  infrequently 
been  made  to  obtain  from  this  hospital  voluntary  in- 
formation concerning  the  private  character  and  diseases 
of  either  present  or  former  patients,  for  the  purpose  of 
aiding  some  prosecuting  attorney.  Such  information 
has  uniformly  been  denied,  on  the  ground  that  the  com- 
munications of  our  patients  to  our  doctors  are  confi- 
dential, are  made  for  purposes  of  intelligent  treatment 
by  our  doctors  of  their  individual  case,  and  are  not  pub- 
lic property.  So  frequently  were  such  requests  made 
that  in  1881  I  requested  the  Counsellor  of  the  Corpo- 
ration to  define  clearly  my  duty  in  the  premises,  and 
received  from  him  the  following :  **  In  a  litigation  where 
a  patient  of  the  hospital  is  a  party,  I  do  not  think  it 
would  be  right  for  the  hospital  to  disclose  to  the  opposite 
party,  from  its  books,  or  through  its  physicians,  facts  re- 
laxing to  such  patient  learned  through  the  connection  of 
such  patient  with  the  hospital,  unless  such  disclosure  be 
required  by  process  of  court  under  the  ordinary  rules  of 
evidence  relating  to  such  matters.  There  might,  how- 
ever,  be  an  exception  to  this  rule  in  a  criminal  matter, 
when  the  information  was  requested  officially  by  the 
District  Attorney." 

This  has  established  the  following  rule  for  the  ad- 
ministration of  this  hospital :  that  when  there  is  any  rea- 
sonable ground  to  question  whether  the  information 
sought  would  or  could  in  any  way  be  used  to  the  disad- 
vantage of  the  patient,  it  is  to  be  studiously  withheld,  un- 
less our  hospital  records  are  called  regularly  into  court 
as  evidence,  when  we  are  obliged  to  testify  to  "the 
truth,  the  whole  truth,  and  nothing  but  the  truth." 

The  facts  in  regard  to  the  case  referred  to  by  Dr.  Fes- 
senden are  that  on  September  9th  I  received  a  letter 
from  a  stranger  in   Salem,  Mass.,  asking,  among  other 

things,  *'  the  cause  of  Mr.  B *s  being  in  the  hospital." 

I  replied,  stating  the  fact  that  Mr.  B had  been  a  pa- 


tient here,  and  giving  the  date  of  his  entry  (March  4th) and 
his  discharge  (April  14th)  as  "cured,"  but  declining  to 
disclose  the  disease  from  which  he  suffered,  and  giving  the 
reasons  why  such  communications  could  not  be  made. 
On  September  i6th  I  received  a  letter  from  Mr.  B — -'s 
brother  in  Boston,  making  similar  inquiries,  and  asking  if  I 
thought  his  brother's  ^*  brains  were  all  right,"  that  <<he 
talked  and  acted  very  strangely."  A  similar  reply  was 
sent.  Again,  on  September  20th,  I  received  a  letter 
from  a  Dr.  Fessenden,  who  was  unknown  to  me,  in  which 

he  says :  "  Mr.  B is  now  with  his  sister  in  Salem, 

having  suddenly  appeared  after  an  absence  of  six  )ears, 
physically  much  emaciated,  almost  in  rags,  and  mentally 
unsound  besides.  I  would  like  to  know  what  was  the 
matter  with  him  while  at  St.  Luke's,  and  whether  he  was 
in  sound  condition  when  he  left." 

Judging  from  all  the  circumstances  of  the  case,  I  could 

not  doubt  that  Mr.  B had  proven  an  unwelcome  guest 

on  his  return  to  Salem,  that  it  was  the  desire  of  his  family 
to  send  him  to  a  lunatic  asylum,  and  that  the  physician 
who  had  already  concluded  that  his  patient  was  *^  men- 
tally unsound  *'  sought  corroborative  evidence  from  this 
hospital.  This,  in  justice  to  our  former  patient,  I  felt  I 
must  decline  to  give.  My  conclusion  as  to  the  reasons 
which  prompted  the  inquiry  are  reinforced  by  my  pub- 
lished letter  to  Dr.  Fessenden,  in  which  is  stated,  at  least 
inferentially,  my  willingness  to  communicate  the  facts  to 

Mr.  B himself,  or  at  his  request  to  his  physician. 

Yours  respectfully, 

George  S.  Baker, 
Pas/or  and  SuferiniendenL 

St.  Lukk's  HospiTALflNswr  Yokk,  October  ii,  1884. 


Iirmij  and  H^w^  ^etwa. 


Official List^  Changis  in  the  StoHotis  and Duiiis  cf  Offiun 
serving  in  tJu  Medical  Department^  United  States  Armif^ 
from  October  5  to  October  11,  1884. 

Clements,  B.  A.,  Major  and  Surgeon.  In  addition 
to  present  duties,  to  take  charge  of  the  office  of  the  Med- 
ical Director  of  the  Department  during  the  temporary 
absence  of  that  officer.  S.  O.  195,  par.  i.  Department 
of  the  Missouri,  September  29,  1884. 

Happersett,  John  C.  G.,  Major  and  Surgeon.  Will 
be  relieved  from  duty  in  Department  of  the  East  and  or- 
dered for  duty  at  Willef  s  Point,  N.  Y.  S.  O.  235,  A.  G. 
O.,  October  7,  1884. 

Woodruff,  Ezra,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  four  months.  S.  O.  235,  A. 
G.  O.,  October  7,  1884. 

Cronkhite,  Henry  M.,  Captain  and  Assistant  Sur- 
geon. Assigned  to  duty  as  Post  Surgeon,  Fort  Reno, 
Indian  Territory.  S.  0. 1 97,  Department  of  the  Missouri, 
October  2,  1884. 

Loring,  Leonard  Y.,  Captain  and  Assistant  Surgeon. 
From  Department  of  the  East  to  Department  of  Califor- 
nia.    S.  O.  237,  A.  G.  0.,  October  9,  1884. 

Harvey,  Philip  F.,  Captain  and  Assistant  Surgeon. 
From  Department  of  Dakota  to  duty  in  Attending  Sur- 
geon's Office,  Washington,  D.  C,  relieving  Robert  W. 
Shufeldt,  Captain  and  Assistant  Surgeon,  who,  on  being 
relieved,  will  report  to  Commanding  Greneral  Depart- 
ment of  the  Missouri  for  duty.  S.  O.  237,  A.  G.  O.,  Octo- 
ber 9,  1884. 

Powell,  J.  L.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month  on  surgeon's 
certificate  of  disability.  S.  O.  204,  Headquarters  De- 
partment of  the  East,  October  8,  1884. 

Spencer,  Wm.  G.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month.  S.  O.  204, 
Headquarters  Department  of  the  East,  October  8,  1884. 


October  i8,  1884.] 


THE  MEDICAL  RECORD. 


447 


McCrmry,  Gbo.,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  at  Fort  Meade,  D.  T.  S.  O. 
n5,  Headquarters  Department  of  Dakota,  October  6, 

1884. 

Taylor,  A.  W.,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  at  Fort  Omaha,  Neb.  S.  O. 
87,  par.  3,  Headquarters  Department  of  the  Platte,  Oc- 
tober 3,  1884. 

Black,  C.  S.,  First  Lieutenant  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  fifteen  days,  to  take  effect 
this  date.  S.  O.  131,  par.  3,  Department  of  Texas,  Sep- 
tember 29,  1884. 

Official  JJst  of  Changes  of  Stations  and  Duties  of  Medical 
Officers  of  the  U.  S.  Marine  Hospital  Service^  July  i 
to  September  30^  1884. 

Bailhache,  p.  H.,  Surgeon.  To  proceed  to  Dela- 
ware Breakwater  Quarantine  Station  as  inspector,  Sep- 
tember 10,  1884,  to  investigate  reported  poUution  of 
Potomac  River  water-supply,  September  20,  1884. 

Miller  T.  W.,  Surgeon.  Granted  leave  of  absence 
for  fourteen  days,  July  10,  1884.  Detailed  as  President 
Board  of  Examiners,  September  2,  1884. 

Wyman,  Walter,  Surgeon.  Detailed  as  Member  Board 
Of  Examiners,  September  2,  1884. 

Long,  W.  H.,  Surgeon.  Granted  leave  of  absence  for 
twenty  days,  July  30,  1884. 

PuRRiANCE,  George,  Surgeon.  Detailed  as  Recorder 
Board  of  £xaminers,  September  2,  1884. 

Stoner,  G.  W.,  Passed  Assistant  Surgeon.  To  pro- 
treed  to  Lewes,  Del.  (Delaware  Breakwater),  as  inspector, 
July  25,  1884.  To  act  as  Quarantine  Officer  at  Dela- 
ware Breakwater,  July  31,  1884* 

Fisher,  J.  C,  Passed  Assistant  Surgeon.  Granted 
leave  of  absence  for  thirty  days,  August  21,  1884. 

GoLDSBOROUGH,  C.  B.,  Passed  Assistant  Surgeon. 
Granted  leave  of  absence  for  thirty  days,  July  12,  1884. 
Leave  of  absence  extended  thirty  days  on  surgeon's  cer- 
tificate of  disability,  August  11,  1884.  Leave  of  ab- 
sence extended  thirtydaySj^without  pay,  September  11, 

Heath,  W.  H.,  Passed  Assistant  Surgeon.  Granted 
leave  of  absence  for  thirty  days,  September  8,  1884. 

Gurr^RAS,  John,  Passed  Assistant  Surgeon.  Granted 
leave  of  absence  for  thirty  days,  September  24,  1884. 

Banks,  C.  £.,  Passed  Assistant  Surgeon.  Granted 
leave  of  absence  for  thirty  days,  August  27,  1884. 

Bennett,  P.  H.,  Assistant  Surgeon.  To  proceed  to 
Buffalo,  N.  Y.,  for  temporary  duty,  September  19,  1884. 

Glen  NAN  A.  H.,  Assistant  Surgeon.  To  proceed  to 
Mobile,  Ala.,  for  temporary  duty,  July  7,  1884. 

Fisher,  J.  C.,  Passed  Assistant  Surgeon.  Resigna- 
tion accepted,  by  the  Secretary  of  the  Treasury,  to  take 
effect  September  30,  1884.     August  21,  1884. 


ptjedical  Stjema. 


Contagious  Diseases — ^Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  October  11,  1884 : 


Week  Ending 


Cas*s, 
October  4, 1884 . 
October  11, 1884 

Deaths. 
October  4,  1884. 
October  11,  1884 


I 


The  Pay  of  the  Medical  Department  during  the 
Revolution  is  given  by  a  writer  in  the  Magazine  of 
American  History  as  follows  :  "  To  the  office  of  Direc- 
tor of  the  Military  Hospitals  was  attached  the  pay  of 
$150  per  month,  two  rations,  one  for  servant,  and  two  of 
forage ;  to  that  of  the  chief  physician  and  surgeon  of  the 
army,  $140  per  month,  two  horses  and  wagon,  and  two 
rations  of  forage ;  to  each  of  the  three  chief  physicians 
and  sorgeons  of  the  hospitals,  $140  per  month  and  two 
rations;  to  the  purveyor,  $130,  and  his  assistant,  $75 
per  month;  to  the  apothecary,  $130  per  month,  and  his 
two  assistants,  $50  per  month  each ;  to  the  fifteen  hos- 
pital physicians  and  surgeons,  $120  per  month  each,  and 
to  each  of  the  twenty«six  mates,  $50  per  month." 


Influence  of  Syphilis  and  Mercury  on  Cholera. 
— M.  Martineau  has  investigated  the  influence  of  syphilis 
and  mercurial  preparations  on  cholera.  His  inquiries 
lead  him  to  believe  that  syphilitic  patients  under  mer- 
curial treatment  are  not  exempt  from  cholera.  In  1849 
and  1865  the  wards  of  the  Lourcine  Hospital  were  full, 
and  the  mortality  from  cholera  was  excessive  there.  M. 
Dujardin-Beaumetz  says  that  syphilis  has  a  fatal  influence 
on  typhoid  fever.  The  patients  from  the  Lourcine  and 
Midi  Hospitals  seized  with  typhoid  fever  are  sent  to  the 
Cochin  Hospital,  where  it  is  the  prevalent  opinion  that 
syphilitic  patients  attacked  with  typhoid  fever  have  re- 
ceived their  death-warrant 

Peptonized  Milk. — In  reply  to  the  questions  raised 
by  Dr.  N.  E.  Oliver  in  a  previous  issue  of  The  Medi- 
cal Record  concerning  peptonized  milk,  a  correspondent 
writes  that  there  is  no  necessity  for  the  use  of  the  soda 
in  peptonizing  milk.     If  two  portions  of  milk  be  prepared 
—one  with  soda  and  the  other  without — no  difference 
can  be  seen  in  the  action  of  the  pancreatic  ferments,  and 
they  will  both  be  digested  in  the  same  time.     The  pan- 
creatic ferments  act  upon  all  food  substances  without  the 
need  or  use  of  ^'  alkali.''     In  digesting  milk  it  is  neces- 
sary to  check  the  action  at  the  desired  stage.     It  was 
originally  proposed  by  Dr.  Roberts  to  do  this  by  bring- 
ing the  heat  to  the  boiling  point,  thus  killing  the  ferment 
But  if  peptonized  milk  is  boiled  at  any  period  short 
of  the  complete  conversion  of  the  caseine  into  peptone, 
it  is  coagulated.     This  coagulation  is  due  to  the  pecu- 
liar substance  into  which  caseine  is  changed  in  the  pro- 
cess of  its  conversion  into  peptone.     The  addition  of 
soda  bicarbonate  was  found  to  prevent  this  reaction,  so 
that  digestion  may  be  checked  by  boiling  at  any  stage  of 
the  digestion,  when  soda  is  used.     The  writer  proposes 
the  chilling  of  the  milk  by  ice  to  check  the  digestion  and 
maintain  at  any  desired  point,  still  preserving,  however,  the 
vitality  of  the  digestive  agent.  Is  the  soda  objectionable  ? 
is  it  in  "  excess  ?"    The  milk-curdling  ferment  acts  upon 
alkaline  milk  (up  to  15  grains  of  soda  to  the  pint)  just  the 
same  as  upon  pure  milk,  but  not  so  quickly.     Woman's 
milk  is  alkaline.     The  stomach  has  two  resources  for  the 
coagulation  of  milk — the  acid  and  the  milk-curdling  fer- 
ment    Therefore  the  soda  as  used  can  hardly  be  con- 
sidered excessive.     There  is  no  doubt  but  that  the  coag- 
ulation of  the  milk  in  the  stomach  places  the  digestion  of 
the  albuminoids  of  milk  upon  the  same  footing  as  other 
albuminoids.     So  it  would  seem  a  self-evident  proposition 
that  in  order  to  render  cow's  milk  a  fair  daily  food  for  the 
average  infant,  as  a  substitute  for  its  mother's  milk,  it  should 
first  be  made  to  quantitatively  approximate  thereto,  and 
then  the  caseine  adequately  altered.     When  this  is  done 
the  milk  does  curd  in  the  stomach,  or  by  the  addition  of 
acid,  precisely  as  does  human  milk — namely,  in  minute 
flocculi.      In   cases   of  disease   of  the  digestive   tract. 


448 


THE   MEDICAL  RECORD. 


[October  i8,  1884. 


how  far  it  is  proper  to  pre-digest  the  caseine,  and  how 
long  to  continue  the  exhibition  of  thoroughly  pre-di- 
gested  milk,  is  a  question  not  within  the  province  of  the 
writer.  In  order  to  use  the  milk  at  night,  the  peptonizing 
agent  can  be  put  into  a  bottle  with  half  a  pint  of  cold 
water,  half  a  pint  of  cold  milk,  and  four  tablespoonfuls 
of  market  cream.  Shake,  and  place  on  ice  at  once. 
There  will  be  no  digestive  action  in  this  situation.  When 
needed,  pour  out  just  enough  for  a  feeding  into  a  tin  cup 
and  hold  over  a  brisk  flame  for  six  minutes,  stirring  con- 
stantly with  a  spoon  and  tasting  often  so  that  it  does  not 
become  too  hot  tp  be  sipped.  Now  pour  into  a  nursing- 
bottle  and  it  is  ready  for  the  child.  When  ice  cannot  be 
conveniently  had,  put  four  tablespoonAls  of  cold  water 
into  a  tin  cup  and  the  proper  proportion  of  peptonizing 
powder.  Mix  well  and  add  four  tablespoonfuls  of  cold 
milk  and  one' of  cream,  and  hold  over  a  flame  for  six  min- 
utes, stirring  constantly  and  tasting  so  that  it  does  not  be- 
come too  hot  to  be  sipped. 

What  Quacks  Can  Do.— Dr.  D.  B.  Smiley,  of  Mid- 
dletown,  N.  Y.,  writes  that  two  "  eclectic"  physicians  in 
that  town  recently  undertook  to  deliver  a  parturient 
woman,  and  did  the  work  in  fifteen  minutes.  The  head 
was  seized  with  the  forceps,  a  towel  wound  round  the 
neck,  and  both  the  quacks  gave  a  long  pull  together. 
Result:  the  head  was  pulled  off"!  The  body  was  then 
turned  and  delivered.  The  result  was  that  the  vagina 
and  perineum  were  torn  to  shreds,  and  the  patient  died 
next  day.  An  inquest  was  called,  and  the  two  quacks 
testified  that,  though  the  urine  had  not  been  passed  for 
twenty-four  hours,  they  had  not  thought  it  advisable  to 
draw  the  water.  One  of  them  stated  that  the  woman's 
temperature,  as  taken  with  his  finger,  was  93°  or  94**. 
This  one  stated  that  the  normal  healthy  temperature  was 
76**  or  80°,  but  might  be  140°.  He  stated  that  he  meant 
blood-heat,  not  the  pulse.  The  other  was  not  altogether 
clear,  but  believed  70°  to  80°  to  be  about  fair,  and  that 
it  was  higher  in  our  Southern  States.  He  used  instru- 
ments ;  an  instrument  for  the  purpose  was  called  a 
barometer.  The  cause  of  death  was  given  in  the  death 
certificate  as  "uterine  paralysis."  The  coroner's  jury 
returned  a  verdict  that  the  death  was  caused  "  from  child- 
birth, superinduced  by  over-protracted  labor  and  a  want 
of  proper  care  anterior  thereto,  and  that,  in  some  respects, 
there  was  had  unskilful  practice  upon  the  part  of  the  at- 
tendant physicians  in  the  case.-'  The  physician  who  gets 
such  surprising  results  with  a  barometer  registers  as  hav- 
ing a  diploma  from  the  Eclectic  Medical  Society  of  New 
York,  October  17,  1877.  It  would  be  interesting  to 
learn  on  what  kind  of  an  examination  that  Society  grants 
its  diplomas,  and  whether  the  barometer  is  in  general  use 
among  eclectics,  and  under  what  circumstances  they  de- 
cide that  a  patient  has  fever;  also,  whether  they  are 
proud  of  their  graduates. 

Gastric  Hysteria. — Dr.  G.  Frank  Lydston,  of  Chi- 
cago, III.,  sends  an  account  of  a  curious  case.  We  fear 
that  his  diagnosis  will  be  disputed,  especially  in  view  of  the 
death  of  the  patient  Hysterical  vomiting  or  gastric  hys- 
teria would  more  likely  cover  the  case. 

"Annie  K ,  sixteen  years  of  age,  living  at  home 

with  her  relatives,  who  were  in  rather  moderate  circum- 
stances. The  young  lady  had  always  been  perfectly 
healthy  up  to  the  age  of  thirteen,  when  she  began  to 
have  periodical  attacks  of  epistaxis,  attended  by  severe 
pain  in  the  lower  part  of  the  pelvis  and  back.  These 
attacks  occurred  at  intervals  of  about  three  weeks. 
Eight  weeks  before  I  first  saw  the  case,  she  had  one  of 
her  usual  attacks,  but  in  addition  was  affected  by  severe 
and  uncontrollable  vomiting.  She  was  seen  by  several 
physicians,  most  of  them,  I  believe,  being  of  the  homoeo- 
pathic persuasion.  A  number  of  diagnoses  had  been 
made,  the  most  prominent  being  gastric  ulcer,  cancer  of 
the  womb,  and  ulceration  of  the  womb.  It  appeared 
upon  inquiry  that  an  elder  sister  of  the  patient  had  died 
from  a  similar  sickness,  the  nature  of  which  had  never 


been  determined.  On  examination  I  found  the  patient 
considerably  emaciated  (no  aliment  had  been  retained 
by  the  stomach  for  eight  weeks,  and  rectal  alimentation 
evidently  had  not  been  thought  of)  and  very  restless  from 
nervous  exhaustion.  On  examining  the  ejecta,  I  found 
them  to  contain  a  considerable  quantity  of  bile,  but  no 
blood.  There  was  no  pain  in  the  epigastric  or  intnu 
scapular  regions,  but  a  great  deal  of  pain  in  the 
limbs  and  head  was  complained  of  The  temperature 
was  normal.  Very  slight  tenderness  over  the  lower  part 
of  the  abdomen,  which  was  probably  exaggerated  by  the 
extremely  nervous  condition  of  the  patient.  On  examin- 
ing the  uterus,  I  found  it  to  be  very  small,  particularly 
as  regards  the  body  of  the  organ.  There  was  no  neo- 
plasm or  other  morbid  condition.  The  ovaries  could  be 
felt  very  indistinctly.  I  accordingly  made  the  diagnosis 
of  reflex  uterine  vomiting,  dependent  upon  non-develop- 
ment of  the  uterus  and  ovaries.  On  the  third  day  after 
my  first  visit,  I  succeeded  in  checking  the  vomiting,  I 
having  meanwhile  attempted  to  support  the  patient  by 
nutrient  enemata.  After  the  vomiting  stopped,  koumiss 
and  small  quantities  of  brandy  were  retained  by  the  stom- 
ach. At  my  last  visit  on  the  evening  of  the  third  day, 
restlessness  and  nervous  irritability  seemed  to  be  increas- 
ing, although  the  pulse  was  stronger  and  less  frequent 
Shortly  after  I  left  the  house,  however,  the  patient  re- 
quested  her  friends  to  leave  the  room  for  a  while  as  she 
wished  to  sleep.  Accordingly  she  was  left  alone  for 
about  five  minutes,  and  when  her  friends  returned  they 
found  her  dead.  At  the  autopsy,  which  was  readily  ob- 
tained, the  stomach  and  other  abdominal  viscera  were 
found  to  be  perfectly  normal.  The  uterus  and  ovaries 
were  rudimentary,  the  former  measuring  about  one  and 
a  half  inch  in  length,  and  the  latter  being  about  the  dimen- 
sions of  good-sized  beans.  The  sexual  organs  were  other- 
wise normal,  with  the  exception  of  a  peculiar  ring  of 
dilated  capillaries  surrounding  the  os  uteri  externum. 
This  was  of  a  bright  red  color,  which  persisted  in  the 
specimen  until  placed  in  preservative  fluid." 

The  Hemorrhoid  Quack. — Dr.  B.  N.  Stevens,  of 
Chillicothe,  Mo.,  writes :  "  We  have  a  class  of  'quacks' 
in  this  part  of  the  country  that  advertise  to  cure  hemor- 
rhoids without  pain,  and  that  they  meet  with  more  or  less 
success  is  proved  by  their  patronage.  You  cannot  get 
a  patient  here  to  submit  to  the  knife  or  ligature.  They 
say  they  will  go  to  the  man  who  can  cure  them  without 
pain,  and  whose  treatment  does  not  require  them  to  be 
laid  up.  Now,  of  course,  they  use  injections.  Will  you 
give  your  experience  with  them,  the  modus  operandi^ 
etc.  ?  "  We  can  only  say  to  this  that  Dr.  Stevens  will 
find  fiill  descriptions  of  the  carbolic  acid  treatment  of 
piles  in  recent  works  on  surgery  or  diseases  of  the  rec- 
tum. The  treatment  is  often  efficient,  but  not  entirely 
firee  from  danger. 

Not  Extra-Uterine  Pregnancy  but  a  Dermoid 
Cyst. — Dr.  Leonard  D.  White,  of  Uxbridge,  Mass., 
writes:  "  In  your  paper  of  August  23,  1884,  1  noticed  a 
short  article  from  the  pen  of  G.  C.  Park,  o'f  Murraysville, 
Pa.,  and  headed  *  Extra-Uterine  Pregnancy,'  etc.  Judg- 
ing from  the  description  alone,  I  wish  to  ask  if  the  tumor 
under  consideration  might  not  more  properly  be  classed 
under  the  head  of  'Dermoid  Cyst.'"  Dr.  Park  in  a 
subsequent  note  admits  that  the  diagnosis  of  dermoid 
cyst  is  probably  the  correct  one. 

The  Florida  Climate. — Dr.  H.  A.  Canfield,  of  Gill- 
more,  Pa.,  writes  that  his  experience  regarding  the  value 
of  the  Florida  climate  has  been  more  in  accord  with  that 
of  Florida  physicians  than  that  of  Dr.  Boyland.  Dr. 
Canfield  and  Dr.  Boyland,  fi-om  the  latter  of  whom  we 
have  received  a  letter  dated  September  1 7th,  agree  in 
urging  the  plan  suggested  by  Dr.  Lancaster,  of  securing 
an  investigation  of  the  Florida  climate  by  a  committee 
of  the  American  Medical  Association. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  a6,  No.  17 


New  York,  October  25,  1884 


Whole  No.  739 


t^xi^xvsCi  l^rtijcljes. 


CONTRIBUTIONS   TO 
THE  ANATOMY   OF  THE   LEMNISCUS. 

With  Remarks  on  Centripetal  Conducting  Tracts 
IN  THE  Brain. 

By  E.'C  SPITZKA,  M.D., 

PKOPBSSOK  or  KSUKO-ANATOMY  AND  PHYSIOLOGY  IN  THE  NBW  YORK  POST-GKAD- 
UATB  MBDICAL  ACHOOU 

(Continued  from  page  497.) 
III. 

In  the  carnivora  the  relations  of  the  pes  and  the  lem- 
niscus are  much  more  intimate,  owing  to  the  lesser 
development  of  the  ganglion  of  Soemmering  and  the 
non-intervention  of  transverse  pons  fibres.  In  a  set  of 
transverse  sections  from  the  brain  of  a  lioness,  it  can 


Fig.  13.— Transverse  Section  through  Posterior  Pair  of  Corpora  Quadrigemina 
and  Anterior  Part  of  Pons  of  a  Lion.  A,  aqueduct ;  Pa,  ganglion  post-optici ; 
A  lemniscus  portion  to  same ;  L|  main  part  of  lemniscus ;  >,  pes  fibres ;  M 
pomtu^PracAimm. 

be  clearly  seen  how  the  middle  lemniscus  area'(L,  Fig. 
13),  which  is  all  along  separated  by  a  molecular  mterval 
from  the  lateral  division  (/)  that  goes  to  the  post-optic  lobes 
(P2),  constitutes  a  united  bundle  with  the  pes.  They 
are  not  separated  even  by  a  connective-tissue  septum, 
and  while  confirmatory  sagittal  sections  have  not  been 
made,  it  seems  from  the  comparative  area,  that  the  lem- 
niscus portion  enters  into  some  union  with  the  substantia 
ni^a  and  with  the  subjacent  part  of  the  pes.  Aside  from 
this  connection,  the  bundle  from  the  pes  to  the  lemniscus 
(pedal  part  of  the  (intermediate)  interolivary  stratum), 
represented  by  the  0-like  areas  on  both  sides  of  the 
raphe,  is  a  well-marked  feature  of  the  lion's  brain. 

In  the  cat  there  is  a  connective-tissue  intercalation 
between  the  pes  and  the  lemniscus,  and  it  is  difficult  to 
decide  from  tranyerse  sections  whether  the  main  division 
of  the  lemniscus  is  in  part  absorbed  by  the  ganglion  of 
Soemmering,  or  lies  dorsad  of  it  or  in  the  pes.  Certainly 
there  is  no  correspondingly  well-marked  field  as  that  rep- 


resented in  L,  of  Fig.  14  (a  section  from  the  .human 
mesencephalon) ;  although  in  lower  levels  the  lemniscus 
is  quite  as  distinct,  though  not  as  large  as  in  man  and 
the  apes. 


Fig.  Z4* 

In  the  lion  there  is  a  slight  separation  between  the 
horizontal  main  lemniscus  and  the  bundle  from  the  pes 
to  the  lemniscus  of  Wernicke  (pedal  part  of  stratum  inter- 
medium) ;  in  the  cat  the  two  approach  more  closely,  and 
the  latter  constitutes  an  angle  (open  dorsad  and  laterad) 
with  the  horizontal  expanse  of  the  former.  A  fortunate 
set  of  sagittal  sections  from  a  cat  reveals  a  remarkable 
confirmation  of  the  course  of  this  fasciculus  in  the  dog, 
as  well  as  an  interesting  relation  to  the  trapezium.  The 
main  part  of  the  stratum  interolivare  breaks  up  into  nu- 
merous bundles,  ramifying  and  meandering  amon^  the 
transverse  bundles  of  the  trapezium,  thus  producmg  a 
beautiful  wickerwork  pattern,*  at  the  cephalic  end  of  the 
trapezium  field  they  re-collect  and  run  exactly  in  the 
situation  of  the  bundle  from  the  pes  to  the  lemniscus  (to 
the  "  tegmentum  "  of  Henle).  The  following  differences 
are  noted  firom  the  case  of  the  human  subject :  i.  The 
bundle  does  not  connect  as  abundantly  with  the  ganglion 
of  Soemmering  ;  perhaps  this  indicates  that  the  apparent 
relation  with  it,  in  man,  is  a  spurious  appearance.  2. 
But  a  small  part  joins  the  pes  permanently ;  the  main 
part  is  in  juxtaposition  for  a  part  of  its  course  only,  it 
leaves  it  to  radiate  under  and  mesad  of  the  nucleus  teg- 
menti  (perhaps  in  part  entering  it)  to  take  a  course 
which  only  basi-parallel  sections  can  expose  (see  dog). 

In  his  latest  work  *  Meynert  says  :  "  Where  these  bun- 
dles of  the  internal  capsule  (certain  intertwined  fasciculi 
from  the  cortex — in  the  diagram  to  be  referred  to  he 
changes  about  and  derives  them  from  the  lenticular  nu- 
cleus) run  in  the  same  height  as  the  opposite  pes  fedun- 
cu/i(he  means  the  proximal  internal  part),  they  admit  pro- 
cesses of  the  substantia  nigra  Soemmeringii^  with  which 
they  are  soldered  into  a  compact  layer  behind  the  super- 
ficial layers.  Where  this  fibre  layer  of  Soemmering* s 
substance,  which  I  term  stratum  intermedium  peduncuiiy 
covers  the  tegmentum  of  the  crus,  it  is  bulged  forward 
by  the  subjacent  red  nucleus  of  the  tegmentum.  In  its 
further  course  the  stratum  intermedium  exhibits  a  con- 
cavity applied  to  the  biconvex  deep  mass  of  transverse 

» This  is  one  of  the  prettiest  pictures  in  cerebral  histo-anatomy  ;  the  stratum  in- 
termediMtn  fibres  bear  an  analogous  relation  to  the  transverse  lemniscus,  as  the 
sagittal  fibres  of  the  pons  bear  to  the  transverse  ones  in  man.  There  are  not  the 
same  mediating  nuclear  intercalations.  Near  the  main  height  of  the  trapezium 
there  is  a  beautiful  set  of  cells,  not  hitherto  described,  these  are  scattered  in  the 
meandering  fibres  in  the  more  dorsal  division,  and  of  considerable  extent.  Not  all 
the  meandering  fibres  appertain  to  this  stratum,  the  dorsal  third  or  more,  are  de« 
rived  from  the  reticular  field  of  the  oblongata. 

*  Psychiatrie,  p.  48. 


4SO 


THE   MEDICAL   RECORD. 


[October  25,  1884. 


fibres  of  the  pons,  and  in  the  oblongata  appears  to  lie 
behind  the  pyramids  as  the  most  anterior  layer  of  the  an- 
terior column,  and  internally  to  the  olive."  *  He  discon- 
nects the  lemniscus  from  the  stratum  intermedium,  with 
which  I  agree  in  thinking  that  it  should  not  be  confounded. 
This  description  corresponds  in  many  features  with  the 
one  I  have  attempted  to  give.  It  is  singular  that  in  the 
most  obscure  part  of  this  tract  Meynert  should  agree 
with  the  most  modern  authorities  so  nearly,  and  yet  differ 
in  regard  to  the  simplest  and  earliest  known  part  of  its 
course  in  a  territory  with  which  he  showed  himself  in  his 
earlier  work  to  be  thoroughly  familiar.  His  plate  of  the 
spinal  cord  (page  124,  loc.  cit.)  only  the  eminence  of  its 
author  saves  fron>  the  epithet  **  puerile."  He  allows  the 
interolivary  stratum  intermedium  to  pass  without  any  de- 
cussation into  the  anterior  column  of  the  cord,  occupying 
the  field  correctly  assigned  by  Flechsig  to  the  undecus- 
sated  part  of  the  true  pyramids.  He  emphatically  de- 
clares that  the  pyramids  decussate  in  toto,  so  that  there 
is  no  other  explanation  for  his  mistake  than  to  suppose 
that  he  sticks  the  (interolivary)  stratum  intermedium 
where  he  loses  it,  to  the  undecussated  part  of  the  pyra- 
mid tract,  where  he  picks  the  latter  up ;  its  upper  origin 
he  either  ignores  or  is  unacquainted  with.  The  latter 
alternative  is  contradicted  by  a  clause  in  his  older  (and 
for  its  day  superior)  treatise  in  Strieker's  collection. 
The  true  course  of  the  stratum  intermedium  (proven 
beyond  question  by  the  secondary  degeneration  of  my 
case)  in  the  piniform  decussation  still  passes  as  a  decus- 
sation of  external  pyramid  fibres,  with  a  slight  doubt. 
This  adhesion  to  the  old  error,  worse  confounded  by  the 
attempt  to  implant  it  on  more  modern  views,  is  utterly 
incomprehensible.'  It  is  true  that  some  fibres  take  the 
course  claimed  by  Lockhart  Clarke,  and  after  him  by 
Meynert,  but  if  the  development  and  atrophy  methods 
(of  which  the  secondary  degeneration  is  one)  are  en- 
titled to  a  moment's  consideration,  they  prove  that  the 
great  mass  of  the  stratum  intermedium  passes  to  the 
nuclei  of  GoU  and  Burdach,  and  that  the  admixture  of 
pyramid  fibres  is  slight.  I  have,  in  an  earlier  part  of  this 
article,  referred  to  the  topographical  misunderstanding  on 
this  head. 

There  is  no  warrant  for  the  designation  of  the  direct 
myelo-cerebellar  tract  by  Meynert  as  'lemniscus  in- 
ferior" (from  the  cerebellum).  Meynerfs  description 
had  been  superseded  by  Flechsig,  who  is  entitled  to  the 
credit  of  its  discovery  (with  Foville).  His  refusal  to  ac- 
cept Flechsig's  name  may  be  a  protest  against  the 
animus  of  Flechsig's  warfare  ;  if  so,  it  is  a  singular  one. 
If  we  include  Meynert's  stratum  intermedium,  the 
alleged  pyramid  tract  in  GoU's  columns,  the  direct 
myelo-cerebellar  tract,  and  the  outer  part  of  the  an- 
terior lateral  column  under  the  term  lemniscus,  we  cover 
pretty  much  the  entire  periphery  of  the  cord  from  the 
bottom  of  the  anterior  fissure  round  to  the  correspond- 
ing part  of  the  posterior." 

The  only  tract  which  is  correctly  entitled  lemniscus  in 
Meynerfs  plate  is  the  '*  lemniscus  superior."  It  is 
greatly  exaggerated,  however,  and  he  who  is  familiar 
with  the  results  of  Flechsig,  which  are  accepted  by  nearly 
all  neurologists,  must  be  puzzled  *  on  seeine  this  superior 

}  The  above  is  a  specimen  of  Meynert's  language,  and  may  serve  to  indicaie  the 
difficulties  under  which  the  translators  of  his  anatomy  labored.  In  plain  English 
a  free  and  logical  rendition,  embodying  a  consistent  use  of  topographical  terms, 
would  be :  "From  the  cortex,  a  flat  layer  of  fibres  converges  toward  the  substan- 
tia nigra^  being  interpolated  between  it  and  the  tegmentum  as  an  tnttrmediate 
stratum.  The  nucleus  tegmenti,  dorsad  of  it,  causes  a  ventrally  convex  depres- 
sion. After  an  admixture  with  the  processes  of  the  substantia  nigra^  this  tract 
courses  over  the  dorsal  pons  fibres,  being  concave  in  correspondence  with  the  con- 
vex contour  of  the  latter.  Below  (caudad  oO  the  pons,  it  seems  to  lie  immediately 
over  (dorsad)  the  pyramid  in  the  triangular  field,  between  the  latter,  the  olive,  and 
the  raphe. 

^  There  is  not  the  slightest  reference  to  the  results  yielded  by  a  study  of  sec- 
ondary degeneration,  though  Mayer's,  Hom^n*s,  and  my  cases  were  published 
between  one  and  two  years  prior  to  the  appearance  of  Meynert's  last  work. 

'  To  characterixe  the  diagram  in  question  further,  it  may  be  stated  that  it  is-- 
where  not  absolutely  erroneous — imperfect  and  theoretiod.  It  does  not  corre- 
spond to  the  present  state  of  science,  and  must  prove  a  serious  disappointment  to 
the  numerous  students  and  admirers  of  Meynert. 

^  If  the  abnormally  diminutive  pyramid  oe  erased,  and  the  designations  of  the 
lemnisd  reversed^  Meynert's  diagram  may  be  turned  up-side  down,  and  will  gain 
by  the  inversion,  masmuch  as  the  uncrossed  part  of  the  pyramid,  and  the  stratum 
intermedium  will  then  come  out  right,  while  the  deeper  fissure  will  occupy  the  cor- 
rect dorsal  (posterior)  position. 


lemniscus  made  to  cover  a  good  half  of  the  periphery  of 
the  cord,  while  the  direct  myelo-cerebellar  tract  covers 
just  one-tenth  as  great  an  area.  In  truth,  the  relation  is 
nearer  the  reverse.  In  Mayer's  case  there  was  second- 
ary degeneration  of  the  (true)  lemniscus.  As  the  case 
was  of  but  a  year's  standing,  it  may  not  have  covered  all 
the  area  it  might  have  ultimately  extended  over;  it 
was  situated  in  a  line  of  prolongation  interniediate  to  the 
lateral  and  anterior  cornua,  and  at  the  periphery.  The 
myelo-cerebellar  tract,  on  the  other  hand,  covers  a  large 
segment  of  the  cord. 

IV. — ^The  Trinbural  Fasciculus. 

Several  years  ago'  I  maintained  that  the  so-called 
round  bundle  of  Clark  and  solitarv  bundle  of  Stilling  was 
not,  as  Krause  claimed,  directly  derived  from  the  spinal 
fibres  of  the  same  side.     I  derived  it  in  the  main  from 
the  piniform  decussation,  which,  as  direct  anatomical  ob- 
servation and  other  n^ethods  referred  to  in  the  foregoing 
show,  is  a  direct  continuation  of  the  .stratum  intermedium 
(interolivare).  At  that  time,  following  Meynert,  I  regarded 
a  larger  part  of  the  lemniscus  as  derived  from  the  ganglia 
of  the  posterior  pair  of  the  corpora  quadrigemina  than  is 
now  done,  and  consequently  supposed  that  these  ganglia 
through  the  discovered  connection,  exerted  their  influence 
on  vegetative  life.     The  trineural  fasciculus  comprises  a 
system  of  fibres  imbedded  in  ganglionic  substance,  into 
which  numerous  of  the  internal  arciform  fibres  can  be 
traced.     In  the  major  part  of  its  course  it  is  constantly 
in  receipt  of  new  fibres  through  this  ganglionic  medium, 
and  expends  others  which  become  roots  of  origin  of  the 
nervus  intermedius  (an  aberrant  branch  of  the  glosso- 
pharyngeal, see  Bigelow's  and  my  own  communications  to 
Thr  Medical  Record  of  1880),  the  n.glosso-pharyngeus 
and  the  n,  vagus.   Most  authors  add  the  spinal  accessor 
to  the  list.     In  my  earlier  communications  I  held  a  re- 
served position  on  this  head,  but  not  venturing  to  con- 
tradict what  was  then  the  unanimous  opinion,  allowed 
but  a  minimum  of  its  fibres  to  that  nerve.      Mendel,  in 
a  discussion  with  Wernicke,  held  in  Berlin,  denied  such  a 
connection  in  toto,  not  only  for  the  accessory  but  also 
the  vagus  nerve;  this  I  think  is  going  too  fiaur.    The 
vagus  does  receive  rootlets  firom  this  fasciculus.     On  the 
other  hand,  I  endorse  his  view,  as  against  Wernicke,  that 
the  accessory  is  not  so  connected.     I  am  not  able  to  de- 
clare as  positively  as  Mendel  does,  and  as  I  did  in  the 
communications  referred  to,  that  the  trineural  fasciculus 
ends  at  the  level  of  the  gustatory  nerves.     It  is  not  im- 
possible that  a  slender  prolongation  continues  on  to  the 
substantia  femiginea  (locus  caeruleus),  though  this  is  a 
mere  suspicion  with  me  at  present. 

As  I  maintained  that  the  trineural  fasciculus  is  a  recur- 
rent branch  of  the  lemniscus  tracts,  its  description  is 
germane  to  our  subject  My  reasons  for  opposing  Krause's 
view  that  it  is  exclusively  a  respiratory  fasciculus  (Respi- 
rations-Btindel)  are  the  following  : 

1.  It  extends  with  undiminished  diameter  beyond  the 
level  of  the  pneumogastric  nerve  and  distinctly  connects 
with  the  glosso-pharyngeal  and  intermediate  nerves." 

2.  If  the  trineural  fasciculus  came  from  the  cord,  its 
origin  would  (Fig.  14)  be  very  near  the  median  line,  in 
districts  which  we  know  have  other  destinations. 

3.  The  fasciculi  of  both  sides  approach  each  other  very 
closely,  suggesting  a  decussation. 

4.  They  or  rather  their  ganglionic  "sheaths**  continu- 
ally receive  arciform  fibres.  These  arciform  fibres  cross 
the  raphe,  and  while  many  running  in  this  direction  are 
from  the  reticular  formation,  the  majority  come  from  the 
olive  and  the  stratum  interolivare. 

5.  While  it  is  not  impossible  that,  the  decussation 
being  established,  such  decussation  may  be  from  below— 

1  Chicago  Journal  of  Nervous  and  Mental  Diseases,  187$^ 
*  Duval  discovered  the  connection  of  the  M^rtms  intermedius  widi  the  aodetf 
of  the  glosso-pharvniseal,  and  I  deaionstrated  an  additional  ori|;m  from  the  tripw 
ral  fasciculus.  Unfortunately  the  chief  specimen  was  ruined  u  dass  deaMosn- 
tion,  so  that  I  am  unable  to  test  some  new  questions  diat  have  aris^,  as  tov^ 
continuatioa  of  the  fasciculus  &rtfaer.  or  as  I  then  tauchc,  its  cesMrinn  at  nil 
level. 


October  25,  1884.] 


THE  MEDICAL  RECORD 


451 


that  isjrom^the  cord,  upward,  and  not,  as  1  maintain,  from 
above  (cephalic),  across  the  median  line  and  reflected 
back  upward  (cephalad)  again — the  direction  of  the  arcu- 
ate fibres  is  against  that  view. 


Fig.  15. — Section  Parallel  to  the  Floor  of  the  Fourth  Ventricle  of  Man.  (Autopsy 
through  Professor  Little.)  sv.,  sulcus  ventriculi  guarti ;  Ic^  locus  caeruleus  cells  ; 
|r,  the  enormous  raphe  root  of  the  sensory  division  of  the  trigeminus  ;  ^g.  gtnu 
fiulialis  :  PI/9  posterior  longitudinal  fasciculus  (oculo-nuchal  co-ordinator|  ;  7a, 
ascending  fibres  to  join  raphe  root ;  /,  cerebellar  myelobracliium,  or  posterior  pe- 
duncle :  //,  fibres  of  redcular  formation  ascending  in  t^mentum  ;  8r,  stria  root 
of  auditory,  imbedded  m  its  (?)  nuclear  subsUnce;  iwm,  nuclear  mass  of  mixed 
system ;  X2w.  nucleus  of  hypoglossal  nerve  ;  /r,  trineural  fasciculi ;  .r/,  ganglionic 
processes,  including  fibres  firom  the  piniform  (sensory)  decussation  ;  ///,  biuidles 
of  latter  divided  across  in  their  ascension. 

6.  Direct  observation  shows  that  the  lowest  demon- 
strable fibres  come  directly  from  the  processes  of  the 
piniform  decussation.  Occasionally  a  process  is  seen 
running  outward,  but  it  cannot  be  traced  far,  and  trans- 
verse sections  show  that  many  rootlets  passing  from 
without  inward  and  over  the  fasciculus,  are  only  curved 
around,  taking  an  arched  course  from  the  same  decussa- 
tional  origin.  All  clear  appearances  demonstrate  a  con- 
nection with  the  decussation. 

The  fibres,  although  regarded  of  similar  optic  appear- 
ance in  transverse  sections,  show  two  well-characterized 
varieties  in  lengthwise  sections.  The  axis  of  the  bundle 
is  composed  of  thicker  fibres  with  broad  myelin  sheaths 
which  have  a  pale  tint  in  the  aggregate,  absorbing  little 
carmine  ;  the  surrounding  fibres  are  finer,  and  in  bulk 
fairly  well  stained,  resembling  the  bundle  which  passes 
from  the  habenula  to  the  outer  peduncular  ganglion  *  in 
this  histological  respect.  In  sections  of  the  same  direc- 
tion as  the  one  represented  in  the  figure,  the  core  bun- 
dle is  not  smoothly  continuous,  but  interrupted,  as  if  it 
consisted  of  slightly  arched  fasciculi,  which  may  emerge 
at  various  points  in  the  course  of  the  fasciculus.  The 
difference  in  the  character  of  the  fibres  would  indicate 
that  the  trineural  fasciculus  acts  as  a  conductor  for  sev- 
eral functions. 

In  the  case  of  secondary  degeneration  of  the  stratum 
intermedium,  the  functions  of  the  mixed  nerves,  as  far  as 
deglutition  was  concerned  was  impaired.  This  fasciculus 
was  healthy,  but  many  of  the  arched  fibres  going  to  it 
were  not — they  had  undergone  degeneration.  One  fascic- 
ulus crossing  out  from  the  raphe,  four  or  five  "branches  " 

1  In  an  earlijer  day  of  cerebral  anatomy,  the  fact  that  the  stratum  interolivare 
becomes  loit  in  about  the  same  region  where  a  part  of  Meynert's  bundle  runs 
Would  have  been  regarded  as  suggesting  a  connection. 


distant  from  the  hypoglossal  nucleus  (that  is,  very  near 
the  dorsal  end  of  the  raphe)  was  entirely  healthy  (Fig. 
3,  /;  also  Fig.  4).  From  the  course  of  its  bundles  in  the 
raphe,  and  its  freedom  from  degeneration,  it  cannot  come 
from  the  interolivary,  but  from  the  true  olivary  and  retic- 
ular field  portion  of  the  lemniscus.  The  fact  that  this 
fasciculus  is  larger  in  the  level  of  Fig.  4  than  that  of 
^ig-  3  proves  conclusively  that  if  there  is  a  spinal  origin 
for  this  bundle  it  must  be  a  very  subsidiary  element. 

Internal  to  the  trineural  fasciculus  there  are  a  num- 
ber of  separate  fasciculi,  continuous  for  as  great  a  length 
and  apparently  originating  in  a  similar  manner.  They 
are  very  clear  in  flat-wise  sections  and  apt  to  be  altogether 
overlooked  in  transverse  ones.  They  cannot  in  higher 
levels  be  confounded  with  the  longitudinal  bundles  run- 
ning in  the  hypoglossal  and  vagus  nuclei  in  lower  levels, 
referred  to  by  Mendel,  though  I  am  not  prepared  to  deny 
a  connection  between  them  in  the  said  lower  levels. 

(To  be  continued.) 


DISEASE  . GERMS. ^ 
By  GEORGE  M.  STERNBERG,  M.D.,  F.R.M.S., 

MAJOR   AND  SURGEON   U.  S.  A. 

It  is  but  a  few  years  since  ''disease  germs"  were  hypo- 
thetical things,  in  regard  to  the  origin,  nature,  form,  and 
modus  Ciperandi  of  which  we  fpossessed  only  vague  and 
uncertain  notions. 

In  this  pre-scientific  peroid  of  etiological  inquiry,  a 
favorite  idea  with  those  who  assumed  the  existence  of 
disease  germs  on  theoretical  grounds  was  that  they  are 
living  particles  detached  from  the  diseased  organism,  ca- 
pable, perhaps,  in  some  instances,  of  self-multiplication 
external  to  the  body,  and  having  the  power,  when  intro- 
duced into  the  body  of  a  susceptible  individual,  of  induc- 
ing morbid  phenomena  identical  with  those  which,  in  a 
preceding  case,  were  the  cause  of  their  origin.  In  other 
words,  that  they  are  both  the  cause  and  the  result  of  the 
morbid  phenomena  which  characterize  the  specific  infec- 
tious diseases. 

No  experimental  evidence  has  thus  far  been  adduced 
in  favor  of  this  conception  of  disease  germs,  which  is  evi- 
dently unphilosophical,  and  is  unsupported  by  observa- 
tion or  analogy.  The  only  detached  living  particles 
known  to  science  which  are  thrown  oflf  from  the  bodies 
of  plants  and  animals,  and  which  are  capable  of  subse- 
quent development,  are  the  reproductive  elements,  the 
function  of  which  is  to  preserve  the  species  and  not  to 
destroy  it ;  and  observation  teaches  that  as  a  general  law 
disease  is  due  to  agents  introduced  from  without,  whereas 
the  view  above  referred  to  would  necessitate  a  belief  in 
the  intrinsic  origin  of  the  specific  infectious  diseases. 
For  there  could  be  no  disease  germs  detached  if  there 
were  no  diseased  organism  to  throw  them  oflf. 

But  the  progress  of  science  has  made  us  acquainted 
with  disease  germs  of  another  kind,  which  being  vegetable 
parasites  must  in  the  first  instance  have  been  of  extrinsic 
origin,  even  if  at  present  they  have,  in  certain  cases,  no 
other  habitat  than  within  the  body  of  the  animal  in  which 
they  produce  specific  morbid  symptoms. 

Thus,  if  it  be  demonstrated — a  very  diflicult  matter, 
by  the  way — that  the  tubercle  bacillus  is  found  only  in 
the  tubercular  products  which  result  from  its  invasion  of 
the  bodies  of  man  and  the  susceptible  lower  animals,  it 
will  be  none  the  less  improbable  that  this  has  always  been 
the  case.  We  must  admit  that  this  bacillus  existed  in 
nature  before  there  was  any  tuberculosis,  or  we  are  forced 
to  one  of  two  conclusions :  either  the  disease  tubercu- 
losis at  one  time  occurred  independently  of  the  bacillus, 
or  the  parasite  was  created  as  it  now  is  and  implanted 
in  the  bodies  of  animals  especially  to  produce  this  dis- 
ease. The  second  alternative  involves  the  acceptance 
of  a  theoretical  conception  which  cannot  be  discussed 
from  a  scientific  standpoint.     It  is  evidently  opposed  to 

»  Read  at  the  meeting  of  the  American|Public  Health  Association  in  St  Louis 
October  17,  Z884. 


452 


THE   MEDICAL  RECORD. 


[October  25,  1884. 


the  scientific  conception  which  has  forced  itself  upon 
careful  students  of  nature  in  all  parts  of  the  world,  and 
which  is  expressed  in  the  word  evolution. 

If  at  any  time  in  the  past  the  disease  tuberculosis  ex- 
isted independently  of  the  tubercle  bacillus,  or  of  any 
other  micro-organism,  then  we  must  deny  that  this  para- 
site has  any  etiological  import,  or  must  at  least  assign  it 
a  secondary  r6le,  viz.,  that  of  carrying  a  non-living  tu- 
bercle virus  from  a  diseased  organism  and  implanting  it 
in  a  new  soil.  In  this  case  the  infectious  character  of 
the  disease  would  depend  upon  the  living  parasite ;  but 
inasmuch  as  the  disease  must  at  some  time  have  orig- 
inated independently  of  the  parasite,  we  could  scarcely 
deny  the  possibility  of  its  intrinsic  origin  at  the  present 
day.  There  is  much  to  be  said  in  favor  of  this  view  of 
the  etiology  of  the  infectious  diseases  ;  but  it  is  opposed 
by  the  experimental  evidence,  which  shows  that  "  pure 
cultures  "  of  known  disease  germs  are  as  potent  in  pro- 
ducing the  specific  morbid  phenomena  as  is  material  de- 
rived directly  from  the  diseased  organism. 

In  the  case  of  anthrax  there  can  be  no  doubt  that  this 
is  true,  and  that  living  anthrax  spores  may  produce  the 
most  virulent  form  of  the  disease  independently  of  any 
non-living  material  derived  from  a  preceding  case.  The 
experiments  of  Koch  seem  to  have  established  the  same 
as  regards  the  tubercle  bacillus,  pure  cultures  of  which 
are  said  to  produce  tuberculosis  in  rabbits  and  in  guinea- 
pigs  as  certainly  and  as  promptly  as  do  inoculations  with 
sputum  or  other  material  derived  directly  from  the  dis- 
eased organism.  These  experiments  have  been  repeated 
by  Watson  Cheyne,  of  London,  with  the  same  result. 

I  cannot  doubt  that  these  gentlemen  have  obtained 
the  results  reported  by  them  from  inoculations  with  pure 
cultures  in  the  sense  that  no  other  micro-organism  was 
present  in  these  cultures.  The  only  possible  question  is 
whether  these  cultures  were  pure  in  the  sense  that  they 
did  not  contain  any  remnant  of  a  non-living  tubercle  vi- 
rus. How  many  successive  cultures  must  be  made  in 
order  to  insure  this  result  we  cannot  definitely  determine, 
but  evidently  more  are  required  when  cultivation  is  con- 
ducted upon  the  surface  of  a  solid  culture  medium,  than  in 
fluid  cultures  in  which  a  considerable  amount  of  fluid  serves 
to  dilute  the  non-living  material  which  in  the  diseased 
organism  is  associated  with  the  living  microbe.  There 
can  be  no  question,  however,  that  a  non-living  poison 
which  originated  in  the  diseased  organism  independently 
of  the  parasite  would,  in  the  end,  be  excluded  by  the 
method  of  successive  cultures,  whether  these  are  made 
in  a  fluid  or  upon  a  solid  substratum.  On  the  other 
hand,  a  virus  produced  by  the  parasite  as  a  result  of  its 
normal  physiological  processes  would  be  present  with  it 
in  each  successive  culture. 

It  may  well  be  that  all  of  the  different  pathogenic  bac- 
teria produce  special  poisons  to  which  their  specific 
action  is  due.  But  a  poison  produced  by  the  parasite 
itself,  whether  grown  in  an  animal  body  or  in  a  culture 
fluid,  is  evidently  secondary  as  an  etiological  agent, 
although  it  may  be  an  essential  factor  in  giving  the  par- 
asite pathogenic  power.  We  may  suppose  that  such  a 
poison  secreted  by  the  invading  micro-organism  prepares 
the  soil  for  its  future  growth  ;  just  as  the  abnormal 
growths  upon  various  plants  known  as  galls  are  supposed 
to  be  produced  by  the  irritant  action  of  some  poisonous 
liquid  introduced  by  the  sting  of  an  insect,  which  at  the 
same  time  deposits  an  ^gg,  A  virus,  on  the  other  hand, 
which  was  produced  in  the  diseased  organism  independ- 
ently of  any  parasite,  but  which  furnished  the  soil  suit- 
able for  the  development  of  a  particular  microbe,  would 
be  the  essential  etiological  agent  in  the  production  of  the 
morbid  phenomena,  and  the  parasite,  if  not  a  mere  epi- 
phenomenon  without  etiological  import,  would  at  least  be 
only  a  secondary  factor,  capable,  perhaps,  of  doing  harm 
by  inducing  changes  in  morbid  products,  as,  for  example, 
the  cheesy  degeneration  of  tubercle  nodules,  and  of 
transporting  the  virus  to  new  localities  and  thus  giving 
the  disease  an  infectious  character. 


As  heretofore  remarked,  this  hypothesis  must  give  way 
before  the  evidence  furnished  by  pure  cultures.  And  it 
must  be  admitted  that  the  experiments  of  Koch  leave 
very  little  ground  for  believing  that  it  is  true  as  regards 
tuberculosis.  It  is  not  safe  yet  to  generalize,  however, 
and  it  does  not  follow  that  it  is  not  true  for  small-pox 
and  other  diseases  in  which  pure  cultures  of  the  parasite 
present  in  diseased  tissues  have  not  been  proved  to  be 
potent  in  the  perpetuation  of  the  morbid  phenomena  in 
other  individuals. 

We  need  a  non-living  poison  or  virus  in  order  to  ex- 
plain the  action  of  the  tubercle  bacillus ;  for  I  do  not 
feel  prepared  to  admit  that  the  effects  which  follow  in- 
oculations  with  pure  cultures  of  this  microbe  are  due  to 
mechanical  irritation  alone.  I  have  recently  repeated 
the  experiments  of  Formad,  of  Philadelphia,  in  which  he 
claims  to  produce  tuberculosis  by  inoculations  with  finely 
powdered  inorganic  material  suspended  in  water.  My 
experiments  have  satisfied  me  that,  when  the  material  is 
thoroughly  sterilized,  and  no  tubercle  bacilli  are  intro- 
duced at  the  same  time,  tuberculosis  does  not  result 
from  such  inoculations.  We  know  that  the  lungs  of  man 
are  very  commonly  loaded  with  particles  of  carbon,  and 
that  these  angular  particles,  which  are  much  larger 
than  the  tubercle  bacillus,  do  not  give  rise  to  the  devel- 
opment of  miliary  nodules.  Therefore,  I  say,  we  need 
something  more  than  the  bacillus  to  account  for  the  for- 
mation of  these  nodules,  in  which  the  parasite  finds  a 
suitable  soil  for  its  development^ 

If  tuberculosis  was  originally  of  extrinsic  origin  and  is 
to-day  produced  by  "pure  cultures"  of  the  bacillus, 
there  can  be  no  question  that  this  something  else  is  ex- 
creted by  the  parasite,  and  is  consequently  ever  present 
with  it  ready  to  produce  its  specific  effect  when  in  con- 
tact with  susceptible  animal  tissues.  Not  all  vegetable 
tissues  react  in  the  same  way  to  the  sting  of  the  various 
species  of  gall-insects,  and  in  like  manner  we  have  differ- 
ences in  susceptibility  to  disease  poisons  among  animals 
of  different  species,  and  among  different  individuals  of 
the  same  species.  The  supposition  that  the  different 
pathogenic  organisms  give  off  different  kinds  of  poisonous 
products  as  a  result  of  their  normal  but  severally  distinct 
physiological  processes,  is  sustained  by  what  is  known  of 
the  action  of  non-pathogenic  organisms  of  the  same  class 
in  various  processes  of  fermentation  and  putrefaction, 
and  by  the  facts  which  relate  to  the  influence  of  protec- 
tive inoculations  and  the  non-recurrence  of  the  specific 
infectious  diseases  in  the  same  individual.  I  have  else- 
where discussed  this  subject  (see  my  work  on  "  Bacteria," 
p.  246),  and  cannot  at  present  give  my  reasons  for  believ- 
ing that  insusceptibility  results  from  acquired  tolerance 
to  the  poisonous  products  evolved  by  pathogenic  organ- 
isms, rather  than  to  a  change  in  the  system  which  has 
rendered  the  soil  unsuited  to  their  development. 

The  question  whether  pathogenic  bacteria  are  distinct 
species  having  permanent  physiological  characters  upon 
which  their  pathogenic  power  depends,  or  whether  they 
are  varieties  of  common  and  usually  harmless  species 
which  acquire  this  power  temporarily  as  a  result  of  special 
conditions  relating  to  their  environment,  is  one  of  the 
greatest  importance,  and  one  which  is  at  present  prom- 
inent in  the  minds  of  the  leading  investigators  in  this 
field. 

Buchner's  claim'  that  the  anthrax  bacillus  is  simply  a 
variety  of  the  common  hay  bacillus,  and  that  one  may  be 
transformed  into  the  other  by  special  methods  of  cultiva- 
tion, has,  upon  fuller  investigation  by  Koch,  Klein,  and 
others,  been  shown  to  be  without  foundation.  We  now 
recognize  not  only  that  these  species  have  distinct  physi- 
ological characters  of  a  permanent  kind,  but  also  that 
during  certain  stages  of  their  development  they  differ 
morphologically.  Indeed,  the  specific  distinction  is  suffi- 
ciently well  marked  by  morphological  characters  alone. 
But  it  does  not  follow  that  there  is  nowhere  in  nature  a 
non-pathogenic  variety  of  the  anthrax  bacillus  from  which 
the  pathogenic  variety  known  to  us  has  been  derived. 


October  25,  1884,] 


THE  MEDICAL  RECORD. 


453 


So,  too,  in  the  case  of  the  tubercle  bacillus  we  are  not 
acquainted  with  any  harmless  bacillus  having  exactly  the 
same  form  and  color  reactions,  and  amon^  known  species 
the  bacillus  of  leprosy  is  the  only  one  which  very  closely 
resembles  it  But  it  must  be  remembered  that  we  have 
only  just  commenced  the  study  of  this  extensive  class  of 
micro-organisms,  and  that  thus  far  it  is  the  pathogenic 
species  which  have  received  the  greatest  attention.  When 
we  come  to  know  more  of  the  bacterial  flora  of  the  ex- 
terior world,  we  may  find  that  all  of  the  species  which 
invade  the  bodies  of  animals  as  harmful  parasites  are 
represented  by  harmless  species  which  cannot  be  distin- 
guished from  them  except  by  the  test  of  inoculating  sus- 
ceptible animals. 

.  In  the  case  of  an  organism  like  the  anthrax  bacillus, 
which  grows  readily  in  a  variety  of  culture  fluids,  and 
within  comparatively  wide  temperature  limits,  it  seems 
altogether  probable  that  the  conditions  necessary  for  its 
growth  may  be  found  external  to  the  bodies  of  animals 
and  outside  of  our  laboratories.  But  it  would  be  an  un- 
warranted assumption  to  suppose  that  its  continuous  de- 
velopment in  this  way  must  necessarily  modify  its  patho- 
genic power.  For  this  is  retained  in  full  force  through 
any  number  of  successive  generations  in  laboratory  ex- 
periments, except  when  the  cultures  are  subjected  to  the 
special  conditions  which  have  been  shown  to  modify  this 
power,  and  which,  following  Pasteur,  we  speak  of  as  ef- 
fecting an  "  attenuation  of  virulence."  The  question  is 
whether  a  similar  attenuation  may^not  be  effected  by  nat- 
ural conditions,  and  whether  the  attenuation  may  not  be 
carried  to  the  vanishing  point.  This  is  possible,  but  we 
have  at  present  no  evidence  that  it  is  true. 

In  the  case  of  the  tubercle  bacillus,  it  has  been  shown 
that  the  conditions  of  development  are  so  restricted  as  to 
soil  and  temperature  required  that  it  may  be  doubted 
whether  these  conditions  are  ever  found  in  nature.  It 
grows  slowly  upon  blood-serum  prepared  by  Koch's 
method,  and  not  at  all  unless  the  temperature  is  very 
carefully  regulated  to  about  38°  C.  Evidently  if  in  a 
tropical  country  the  temperature  were  sufficiently  ele- 
vated and  uniform  to  insure  its  development,  the  proper 
pabulum  mi^ht  be  wanting ;  or  if  this  were  present  other 
bacteria  which  multiply  more  rapidly  would  most  cer- 
tainly take  possession  of  it,  in  the  absence  of  artificial  pre- 
cautions for  their  exclusion,  before  the  tubercle  bacillus 
had  fairly  commenced  to  grow.  It  seems  probable,  there- 
fore, that  this  bacillus,  as  we  know  it,  has  no  external 
habitat,  and  that  it  depends  for  its  existence  upon  the 
conditions  which  it  finds  within  the  bodies  of  animals  sub- 
ject to  the  disease  tuberculosis. 

But,  for  reasons  already  given,  we  are  forced  to  the 
conclusion  that  at  some  time  in  the  past  this  bacillus  had 
an  external  habitat ;  else  we  must  concede  that  the  dis- 
ease tuberculosis  was  originally  of  intrinsic  origin  and 
must  relegate  Koch's  bacillus  to  a  secondary  place  in  its 
etiology.  We  have  among  the  higher  animal  parasites  a 
certain  number  which  have  the  power  to  shift  for  them- 
selves and  to  bring  up  a  family  independently  of  the 
host  upon  which  they  habitually  depend  for  their  susten- 
ance. Others  depend  entirely  upon  their  host,  and 
students  of  biology  are  familiar  with  the  singular  mbdifi- 
cations  which  many  of  these  have  undergone  to  fit  them 
for  their  parasitic  existence,  and  which  make  it  impossi- 
ble for  them  to  exist  independently  of  the  animal  which 
they  infest.  No  doubt  is  any  longer  entertained  with  re- 
gard to  the  fact  that  the  structural  anomalies  exhibited 
by  these  parasites  are  due  to  modifications  which  have 
been  effected  gradually,  and  that  useless  organs  have  dis- 
appeared and  useful  ones  have  attained  a  special  de- 
velopment under  the  influence  of  conditions  relating  to 
the  environment  of  the  parasite  and  in  accordance  with 
the  laws  of  natural  selection. 

It  is  probable  that  the  minute  vegetable  parasites 
which  we  know  as  '<  disease  germs  "  have  in  like  manner 
ttndef|^ne  various  modifications,  if  not  in  form  at  least 
in  their  physiological  characters  ;  and  it  may  be  that  some 


of  them  have  thus  lost  the  power  of  independent  exist- 
ence under  natural  conditions.  Others  may  find  the 
conditions  essential  to  their  development  both  within  and 
without  the  bodies  of  animals.  Indeed,  we  know  that 
such  is  the  fact  as  regards  several  species  which  have 
been  shown  by  laboratory  experiments  to  have  the  power 
of  inducing  infectious  and  fatal  forms  of  disease  in  cer- 
tain animals,  and  which,  nevertheless,  exist  widely  dis- 
tributed in  nature.  Koch's  bacillus  of  induced  septicae- 
mia in  the  mouse,  the  bacillus  of  malignant  oedema,  which 
is  much  larger  and  closely  resembles  the  anthrax  bacillus, 
and  the  micrococcus  of  induced  septicaemia  in  rabbits, 
which  I  have  especially  studied,  are  all  disease  germs  of 
this  kind.  Their  pathogenic  power  is  not  a  temporary 
character,  but  is  limited  to  certain  species  of  animals  in 
the  bodies  of  which  they  find  conditions  favorable  for  their 
development ;  and,  so  far  as  we  know,  the  infectious  dis- 
eases which  they  induce  do  not  arise  spontaneously  in 
these  animals. 

Other  disease  germs,  such  as  the  micrococcus  of  fowl 
cholera  and  that  of  swine  plague,  are  only  known  to  us 
because  they  induce  these  forms  of  disease,  and  the  ques- 
tion whether  they  exist  in  nature,  independently  of  the 
animals  which  they  infest,  has  not  been  definitely  settled. 
If  they  do,  we  should  expect  to  hear  of  the  development 
of  these  diseases  independently  of  infection  directly  trace- 
able to  a  similarly  diseased  animal.  I  am  not  sufficiently 
familiar  with  the  evidence  to  say  whether  it  supports  this 
view  of  the  case  or  not  But  as  regards  the  ^erm  of 
typhoid  fever,  which  we  can  scarcely  fail  to  believe  in, 
although  there  has  been  no  satisfactory  scientific  demon- 
stration of  its  existence,  and  as  regards  th^  cholera  bacillus 
— or  spirillum — of  Koch,  which,  there  is  good  reason  to 
believe,  bears  an  essential  etiological  relation  to  the  Asi- 
atic pestilence,  there  seems  to  be  ample  evidence  of  power 
of  multiplication  external  to  and  independently  of  the 
human  organism.  We  have  known  for  some  time  that 
the  germs  of  these  diseases  are  sown  in  the  discharges  of 
those  suffering  from  them  ;  that  certain  conditions  as  to 
organic  pabulum  and  temperature  are  necessary  for  the 
germination  and  rapid  multiplication  of  this  kind  of  seed ; 
and  that  the  evidence  of  such  germination  and  multiplica- 
tion is  found  in  an  abundant  harvest  of  fresh  victims. 

But  do  these  germs  in  their  external  development 
undergo  modifications  which  cause  them  to  lose  or  to 
gain  in  pathogenic  power,  and  are  they  ever  harmless 
organisms  which  may  be  introduced  into  the  human 
intestine  with  impunity?  The  wide  difference  in  the 
malignancy  of  different  epidemics  and  the  fact  that  dur- 
'ing  the  same  epidemic  the  disease  may  at  first  assume 
a  mild  form  and  subsequently  develop  a  most  malignant 
character,  indicates  that  the  germ,  if  it  be  in  truth  the 
essential  factor  in  the  production  of  the  disease,  must 
undergo  modincations  of  its  pathogenic  power.  And 
once  having  admitted  the  possibility  of  such  modifications, 
it  is  hard  to  place  a  limit  upon  them. 

There  are  two  infectious  diseases  of  man,  one  of  which 
has  been  lately  proved  to  be  due  to  an  invasion  of  the 
affected  tissues  by  micro-organisms,  and  the  other  of 
which  I  can  scarcely  doubt  has  a  similar  etiology,  which 
seem  to  me  strongly  to  support  the  view  that  bacteria 
which  are  ordinarily  harmless  may,  as  a  result  of  special 
conditions  relating  to  their  environment,  acquire  patho- 
genic power.  These  diseases  are  erysipelas  and  hospital 
gangrene.  It  seems  to  me  beyond  question  that  these 
diseases  may,  under  certain  circumstances,  originate  de 
novo,  that  is,  without  direct  or  indirect  infection  from  a 
preceding  case.  And  hospital  gangrene  especially  is  so 
rare  a  disease  that  we  can  hardly  suppose  that  the  out- 
breaks which  occasionally  occur  at  widely  remote  locali- 
ties are  necessarily  connected  with  preceding  cases,  al- 
though these  diseases  are  known  to  be  highly  infectious 
and  to  cling  to  infected  hospital  wards  with  great  tena^ 
city. 

I  have  in  mind  an  outbreak  of  hospital  gangrene  which 
occurred  under  such  circumstances  as  seem  to  me  to 


454 


THE  MEDICAL   RECORD. 


[October  25,  1884. 


justify  the  belief  that  the  epidepiic  was  of  local  origin.  In 
the  summer  of  1862  a  large  number  of  sick  and  wounded 
men  from  the  army  of  the  Potomac  were  placed  upon  a 
transport  vessel  at  Harrison's  Landing,  Va.,  and  brought 
directly  to  Portsmouth  Grove,  R.  I.  This  location  pos- 
sessed great  natural  advantages  both  from  a  sanitary  and 
from  an  aesthetic  point  of  view,  and,  before  the  arrival  ' 
of  this  ship-load  of  sick  and  wounded  soldiers  enjoyed  a 
high  reputation  for  salubrity.  A  quiet  summer  hotel, 
looking  out  upon  the  waters  of  Narraganset  Bay,  formed 
the  nucleus  of  the  general  hospital  which  was  quickly 
built.  Until  this  was  completed  the  patients  were  cared 
for  in  hospital  tents.  Soon  after  the  completion  of  the 
hospital  building  I  was  ordered  to  Portsmouth  Grove,  and 
upon  my  arrival  there  was  placed  in  charge  of  the  sur- 
gical wards.  These  were  detached  frame  buildings, 
made  of  new  lumber  and  constructed  upon  the  plan 
which  had  been  adopted  for  our  barrack  hospitals,  and 
which  is  generally  conceded  to  have  been  excellent.  My 
wards  were  full  of  cases  of  suppurating  gunshot  wounds. 
This  was  before  the  days  of  carbolic  acid,  at  a  time  when 
we  had  no  positive  knowledge  of  disease  germs,  and  be- 
fore we  had  learned  to  look  upon  a  sponge  as  an  abomina- 
tion not  to  be  admitted  to  a  surgical  ward.  My  patients 
were  treated  in  the  usual  manner  with  cold-water  dress- 
ings to  recent  wounds,  and  frequently  renewed  absorbent 
dressings  and  ablutions  with  warm  water  when  suppura- 
tion was  fairly  established  and  there  was  no  inflammation. 
I  dare  say  the  saucers  for  giving  off  chlorine  gas,  which 
were  in  those  days  supposed  to  be  an  important  element 
in  maintaining  the  purity  of  the  atmosphere  in  the  wards 
of  our  military  hospitals,  were  duly  arranged  beneath  the 
several  beds.  Whether  they  were  or  were  not,  a  matter 
in  which  my  memory  does  not  now  serve  me,  is  of  small 
importance;  for  we  now  know  that  it  is  impossible  to 
disinfect  the  air  of  an  occupied  apartment,  and  that  the 
presence  of  chlorine  gas  or  of  carbolic  acid  in  respirable 
amounts  has  no  terrors  for  disease  germs. 

Up  to  a  certain  point  my  patients  continued  to  do 
well,  but  after  a  time  1  recognized  the  presence  of  some 
malign  influence  in  the  wards  which  was  counteracting 
the  vis  medicatrix  natura  upon  which  I  relied  for  the 
cure  of  these  gunshot  wounds,  and  which  caused 
wounds  that  had  previously  been  healing  kindly  to  as- 
sume an  angry  look  and  Co  discharge  an  undue  amount 
of  unhealthy  pus.  Very  soon  the  condition  of  some 
of  these  suppurating  wounds  became  still  more  alarm- 
ing. Instead  of  a  simple  arrest  of  the  healing  process 
and  an  unhealthy  discharge,  I  had  to  deal  with  a  rapidly 
extending  necrosis  of  the  tissues.  The  most  trifling 
wounds  in  robust  young  men  which  were  cicatrizing 
in  a  most  satisfactory  manner,  as  well  as  those  more 
serious  injuries  which  had  necessarily  given  rise  to  pro- 
tracted suppuration  and  depression  of  the  vital  powers, 
would  suddenly  commence  to  extend  by  sloughing, 
and  a  superficial  wound  the  size  of  a  twenty-five-cent 
piece  was  liable  within  two  or  three  days  to  become  an 
ugly  and  deep  sloughing  ulcer  the  size  of  my  hand  or 
larger.  In  a  word,  I  had  to  deal  with  that  dread  disease 
hospital  gangrene.  I  can  hardly  doubt  that  this  rapidly 
developed  necrosis  of  tissue,  extending  from  the  wound 
as  a  centre,  was  due  to  invasion  by  some  micro-organism, 
and  I  infer  that  the  pathogenic  power  exhibited  by  this 
h3rpothetical  organism  was  developed  in  my  wards  as  a 
result  of  exceptional  conditions  of  environment  by  some 
omnipresent  and  usually  harmless  microbe.  Otherwise, 
how  is  it  that  solitary  cases  of  suppurating  wounds  scat- 
tered far  and  wide  over  the  country  never  become  affected 
with  this  disease,  which  only  occurs  where  numbers  of 
wounded  men  are  massed  in  hospitals  ?  That  the  disease 
was  a  local  one,  due  to  some  noxious  agent  which  in- 
vaded the  wound,  and  which  was  transmissible  from 
one  to  another,  and  was  not  due  simply  to  a  depressed 
condition  of  the  general  health  of  those  attacked,  was 
evident.  This  was  especially  shown  by  the  results  at- 
tained by  vigorous  local  treatment  in  connection  with  the 


segregation  of  patients  and  general  measures  of  disinfec- 
tion, when  by  the  thorough  use  of  the  actual  cautery  or  of 
fuming  nitric  acid  the  entire  wound  was  thoroughly  and 
deeply  cauterized,  the  infectious  agent  was  destroyed,  and 
the  vis  medicatrix  natura  proved  sufficient  to  efiect  a 
speedy  cicatrization  of  the  deep  and  broad  ulcers  which 
resulted  from  the  rapid  sloughing  and  the  heroic  treat- 
ment required  to  arrest  it.  Facts  of  this  kind,  taken  in 
connection  with  circumstances  relating  to  the  gradual 
development  of  malignancy  in  local  epidemics  of  other 
infectious  diseases,  such  as  diphtheria  and  scarlet  fever^ 
and  the  evidence  relating  to  attenuation  of  pathogenic 
power  in  known  disease  germs,  cause  me  to  give  more 
weight  to  the  supposition  that  this  pathogenic  power  may 
in  certain  cases  be  an  acquired  physiological  character, 
rather  than  an  inherent  and  specific  one,  than  is  ac- 
corded to  it  by  Koch  and  some  other  leading  investigators 
in  this  field.  I  believe,  however,  that  Koch  admits  the 
possibility  that  his  cholera  bacillus  may  be  a  pathogenic 
variety  of  a  harmless  organism.  At  least  he  has  submitted 
the  question  for  discussion. 

Klein,  of  London,  also  favors  the  idea  that  pathogenic 
power  is  a  specific  and  constant  character  belonging  to 
the  micro-organisms  which  exhibit  it  We  must  admit 
that  this  is  true  in  the  case  of  such  diseases  as  small-poz 
and  measles,  if  they  are  in  truth  germ  diseases,  for  we 
have  no  evidence  that  these  diseases  ever  originate  in- 
dependently of  preceding  cases,  or  that  the  infectious 
principle  is  capable  of  multiplication  external  to  the 
human  body.  But  I  am  very  much  inclined  to  believe, 
for  reasons  already  given,  that  it  is  not  true  as  regards 
the  various  septic  organisms  which  are  known  to  us  by 
laboratory  experiments.  I  am  convinced,  however,  that 
there  are  among  these  lowly  plants  a  large  number  of 
distinct  species,  each  having  its  own  independent  life- 
history,  and  each  subject  to  modifications  of  function, 
and  possibly  of  form,  as  a  result  of  gradual  changes  in  its 
environment. 

Billroth  and  some  of  the  earlier  observers  maintained 
that  the  various  forms  of  bacteria  which  are  found  in 
organic  infusions  belong  to  a  single  species  of  plants — 
the  coccobacteria  septica  of  the  author  named.  But  this 
view  is  no  longer  tenable.  Nor  can  I  agree  with  Nageli 
that  there  exist  but  a  small  number  of  species,  each  of 
which  may  assume  a  variety  of  forms.  This  author  has 
said :  *'  Each  of  the  veritable  species  of  schizomycetes  is 
not  limited  to  presenting  itself  under  the  different  forms 
of  micrococcus^  bacterium^  vibrio^  and  spirillum^  but  can 
also  show  itself  as  the  agent  of  the  acidification  of  milk, 
of  putrefaction,  and  as  the  agent  producing  several  mala- 
dies.'' My  own  observations  have  convinced  me  that  there 
are,  for  example,  numerous  species  of  micrococci,  and 
that  micrococci  never  under  any  circumstances  develop 
into  elongated  or  spiral  bacteria,  and  do  not  form  en- 
dogenous spores,  their  life-history  consisting  in  multi- 
plication by  binary  division.  I  have  had  in  cultivation 
at  different  times  several  different  species  of  these  minute 
plants,  and  have  found  that  by  proper  precautions  pure 
cultures  may  be  maintained  through  successive  genera- 
tions. In  other  words,  that  the  several  species  "  breed 
true."  Thus  the  yellow  micrococcus — M.  luteus — ^pro- 
duces successive  generations  of  yellow  micrococci ;  and 
although  the  individual  cocci  cannot  be  distinguished  by 
their  form  alone  from  other  micrococci  having  a  different 
color,  yet  this  character  being  constant  is  a  sufficient 
specific  distinction.  The  known  species  of  bacilli  which 
may  be  distinguished  from  each  other  by  form,  dimen- 
sions, or  physiological  reactions,  are  already  sufficiently 
numerous,  and  I  cannot  doubt  that  the  number  of  un- 
known species  is  far  greater.  Our  knowledge  of  this 
extensive  microscopic  flora  is  still  very  incomplete,  and 
is  obscured  by  erroneous  observations  and  the  confusion 
which  has  arisen  from  the  minute  size  of  these  micro- 
scopic plants  and  the  intermingling  of  numerous  species 
in  the  same  organic  infusions.  Methods  of  isolating  and 
maintaining  pure  cultures  of  the  several  species  which 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


455 


have  been  devised,  and  especially  Koch's  method  of 
sur£Eu:e  cultivation,  together  with  improvements  in  tech- 
nique and  in  optical  appliances  which  have  been  made 
within  the  past  few  years,  have,  however,  opened  the  way 
for  rapid  progress  in  the  future,  and  we  may  hope  that 
before  many  years  we  will  know  much  more  abput  disease 
germs  than  we  know  to-day,  and  that  the  important 
questions  to  which  I  have  briefly  referred  relating  to 
their  origin,  relationships,  and  modus  operandi  will  finally 
be  settled  by  the  experimental  method. 

Unless,  however,  the  few  individuals  in  this  country 
who  have  endeavored  to  take  part  in  these  researches 
receive  more  encouragement  and  substantial  assistance 
from  some  source  in  the  future  than  they  have  received 
in  the  past,  we  shall  have  the  humiliation  of  still  receiv- 
ing our  knowledge  of  disease  germs  at  second  hand,  and 
of  knowing  that  this  great  nation,  which  has  taken  the 
lead  in  so  many  branches  of  scientific  research,  has  con- 
tributed little  or  nothing  to  this  important  subject. 

I  ^shall  now  endeavor  to  make  you  familiar  with  the 
morphology  of  a  few  disease  germs,  and  with  that  of  some, 
harmless  organisms  of  the  same  class,  by  projecting  upon 
the  screen  some  of  my  photographs  from  nature — photo- 
micrographs. Should  any  gentlemen  of  the  press  be 
present,!  beg  that  they  will  not  refer  to  the  objects  which 
they  are  about  to  see  upon  the  screen  as  "  bugs,"  as  did 
an  intelligent  reporter  in  New  Orleans  in  giving  an  ac- 
count of  a  lecture  illustrated  'in  the  same  way  which  I 
delivered  in  that  city  some  years  since.  By  the  way,  the 
popular  idea  of  a  disease  germ  in  the  city  referred  to  at 
the  time  mentioned  seems  to  have  been  that  it  is  a  bug 
of  some  kind ;  for  in  the  Mardi  Gras  procession  of  the 
same  year,  an  honored  member  and  vice-president  of 
this  association,  whose  death  we  were  soon  after  called 
upon  to  mourn,  made  his  appearance  in  papier-macht 
upon  one  of  the  flats,  as  engaged  in  fishing  for  germs.  In 
his  hands  was  a  slender  fishing-rod  furnished  with  a  hook 
and  line,  and  from  the  hook  dangled  a  nondescript 
creature  which  represented  a  recently  captured  germ, 
and  which  resembled  a  Louisiana  mosquito  more  than 
anything  else;  perhaps  this  was  the  most  pestiferous 
creature  with  which  the  inventor  of  this  tableau  was  ac- 
quainted. At  that  time  a  '^  germ-hunter "  was  thought 
by  many  good  citizens,  and  by  not  a  few  of  our  own  pro- 
fession, to  be  a  crank  who  deserved  no  encouragement, 
and  was  a  fair  subject  for  the  shafts  of  ridicule  and  scorn* 
But  the  world  moves,  and  many  of  these  honest  citizens, 
including  some  of  the  then  scornful  members  of  our  own 
profession,  are  now  prepared  to  swallow  germs  served  up 
in  any  style,  so  long  as  they  are  imported.  And,  indeed, 
they  may,  in  my  opinion,  swallow  with  impunity  some  of 
these  imported  germs,  as  for  example  the  bacillus  malaria 
of  Klebs  and  Tomassi-Crudeli,  or  the  yellow  fever  germ  of 
Domingos  Freir6,  of  Brazil. 

Although  I  object  to  my  disease  germs  being  called 
bugs,  I  cannot  find  fault  with  another  gentleman  of  the 
press,  who,  on  a  different  occasion,  gave  his  impressions 
of  the  morphology  of  the  objects  which  he  had  seen  upon 
Ac  screen  by  telling  the  readers  of  the  journal  which  he 
represented  that  some  of  these  objects  looked  like 
Bologna  sausages  and  some  like  oysters  on  the  half 
shell.  You  will  at  once  recognize  the  Bologna  sausages 
when  the  photo-micrograph  of  a  chain  consisting  of  four 
bacilli  is  projected  upon  the  screen,  but  I  am  still  in 
doubt  which  of  my  photographs  from  nature  suggested 
oysters  on  the  half  shell. 


NASO  -  PHARYNGEAL  FIBRO  -  SARCOMA  RE- 
MOVED WITH  GALVANO-CAUTERY  feCRA- 
SEUR.' 

By  R.  p.  LINCOLN,  M.D., 


NBW  YORK. 


State  Medical  Examiners  in  Pennsylvania.— At 
a  stated  meeting  of  the  Philadelphia  County  Medical 
Society,  held  October  ist,  resolutions  approving  of  the 
appointment  of  a  State  Board  of  Examiners,  and  direct- 
ing the  appointment  of  a  committee  to  draft  a  law  for  the 
creation  of  such  a  Board,  were  unanimously  adopted. 

M.  Charcot  has  been  elected  a  member  of  the  French 
Academy  of  Sciences,  in  place  of  the  late  Baron  Cloquet. 


The  specimen  I  present  to  the  Society  to-night,  I  removed, 
July  22d,  from  a  boy  sixteen  years  of  age.  The  history 
of  the  case  is  in  brief  as  follows :  The  patient  is  of  Irish 
parentage,  never  very  strong  and  always  a  suflferer  from 
nasal  catarrh.  He  first  noticed  obstruction  to  nasal  res- 
piration in  the  autumn  of  1881.  At  that  time,  and  ever 
since,  he  has  had  frequent  hemorrhages,  the  blood  flowing 
first  from  the  right  nostril,  but  soon  from  both  nostrils 
and  the  mouth.  The  quantity  must  have  been  consider- 
able, for  he  described  it  as  at  times  amounting  to  bowl- 
fuls. 

It  was  usually  excited  by  active  exercise,  as  running  ; 
latterly  stooping  would  start  it.  Sometimes  he  would  be 
awakened  at  night  by  a  hemorrhage. 

In  the  spring  of  1882  the  right  nostril  was  stopped  up, 
and  within  a  year  of  this  time  both  were  occluded.  About 
a  year  ago  the  tumor  appeared  to  view  at  the  margin  of 
the  right  nostril,  and  at  about  the  same  time  it  could  be. 
seen  in  the  pharynx  when  the  mouth  was  opened. 

In  November,  1882,  an  attempt  was  made  to  remove 
the  tumor  by  means  of  ordinary  polypus-forceps,  but  was 
abandoned  without  accomplishing  the  desired  result  I 
first  saw  saw  the  patient  July  12,  when  he  was  referred  to 
me  by  Dr.  Satterthwaite.  At  that  time  there  was  a  slight 
but  noticeable  fulness  of  the  right  side  of  the  nose.  The 
right  nostril  was  filled  to  its  margin  with  a  growth 
covered  with  mucous  membrane  of  a  pink  color.  The 
septum  nasi  was  crowded  well  over  to  the  left.  On  ex- 
amining through  the  mouth,  the  soft  palate  was  seen 
deflected  to  a  perpendicular,  extending  a  little  below  its 
border,  and  filling  the  post-nasal  space  and  pharynx  was 
a  tumor  of  the  same  appearance  as  that  in  the  nostril,  but 
with  its  inferior  pear-shaped  base  rough  and  ulcerated  in 
spots. 

A  further  examination  proved  that  the  two  presenting 
masses  were  parts  of  the  same  tumor,  and  attached  to  the 
vault  of  the  pharynx  and  roof  of  the  right  nostril  with  a 
large  pedicle  and  extensive  attachment.  As  the  growth  was 
very  large,  exceedingly  vascular,  and  evidently  growing 
rapidly,  I  advised  an  immediate  operation  with  the  gal- 
vano-cautery  6craseur,  without  the  preliminary  treatment 
by  electrolysis,  which  I  have  heretofore  practised  in 
similar  cases  treated  and  reported  by  me.  I  also  insisted 
that  subsequently  the  stump  should  be  thoroughly  de- 
stroyed by  means  of  the  galvano-cautery.  Other  reasons 
that  influenced  me  in  deciding  to  operate  at  once  was, 
that  I  had  prepared  to  leave  the  city  till  September,  and 
I  feared  that  a  delay  till  my  return  would  find  the  patient 
still  more  reduced  physically  than  at  this  time.  More- 
over, a  fatal  termination  was  liable  to  happen. 

July  2 2d. — With  the  kind  assistance  of  Drs.  Satter* 
thwaite,  Goodwillie,  and  McCarroll,  I  proceeded  to  oper- 
ate, at  the  hospital  of  the  New  York  Post-Graduate  Medi- 
cal School,  in  the  following  manner  :  The  patient  having 
been  anaesthetized  I  passed  along  the  floor  of  the  right 
nostril  a  looped  platinum  wire,  protected  by  a  double 
canula,  the  two  parts  of  which  could  be  disengaged  fron» 
each  other  without  removal,  for  the  greater  facility  of 
carrying  the  wire  around  the  base  of  the  tumor.  The 
loop  being  brought  to  the  margin  of  the  palate,  was  drawn 
backward,  opened,  and  carried  below  and  behind  the 
pendulous  portion  of  the  tumor  up  to  its  attachment  at 
the  base  of  the  skull.  This  was  accomplished  by  the 
conjoined  manipulation  of  the  fingers  of  one  hand,  while 
the  two  parts  of  the  canula,  now  separated,  were  operated 
by  the  other  hand,  and  at  the  same  time  withdrawn,  leav- 
ing the  wire  surrounding  the  pedicle  at  its  base.  The 
terminals  of  the  wire   were  next   passed   through   the 


1  Presented  at  the  New  York  Patholopcal  Society,  October  8,  1884. 


456 


THE  MEDICAL  RECORD. 


[October  25,  1884, 


leader  of  the  galvano-cautery  handle,  and  having  been 
tightened  and  connected  to  the  battery,  the  pedicle  was 
slowly  cut  through  without  hemorrhage.  The  tumor  was 
then  withdrawn  through  the  mouth.  It  measured  in  its 
greatest  length  four  inches,  and  two  and  a  half  in  thick- 
ness, the  latter  being  the  portion  that  extended  into  the 
pharynx,  while  the  form^f  was  the  part  that  protruded 
into  the  nostril.  The  cauterized  surface  measured  two 
inches  by  one  and  three-fourths.  Its  weight,  five  days 
after  the  operation,  was  two  ounces  and  three-fourths. 
Its  freshly  cut  surface  presented  a  bluish-white  fibrous 
appearance,  mottled  here  and  there  with  a  purple  color 
marking  the  seat  of  interstitial  hemorrhages. 

Dr.  George  R.  Elliott  kindly  made  a  microscopic  ex- 
amination of  the  tumor  and  pronounced  it  a  fibro- 
sarcoma. 

On  account  of  the  interest  attached  to  this  case,  I  will 
quote  in  full  Dr.  Elliott's  report. 

"  There  are  round  and  spindle  cells,  having  large  gran- 
ular nuclei;  there  are  also  branching  cells  distributed 
throughout  the  entire  mass,  and  in  places  these  cells  are 
^gregated  together.  In  many  portions  of  the  tumor 
true  fibrillated  tissue  is  present.  The  above  tissue  ele- 
ments are  present  in  the  following  order  as  regards  bulk  : 
First,  fibrous  tissue ;  second,  sarcomatous  tissue  (round 
and  spindle  cells) ;  third,  myxomatous  tissue  (round  and 
spindle  cells).  The  tumor  is  quite  vascular,  and  numerous 
sites  of  hemorrhage,  old  and  recent,  exist.  In  the  fibrous 
portions  the  walls  of  the  blood-vessels  are  greatly  thick- 
ened. In  the  truly  cellular  portions  of  the  growth  the 
vessels  have  no  distinct  walls,  and  appear  to  be  mere 
vascular  channels  running  throughout  the  cellular  sub- 
stance." 

A  week  after  the  operation  I  examined  the  patient  at 
my  office,  and  found  the  cut  surface  well  cleared  off  and 
presenting  an  apparently  healthy  wound,  and  appointed 
the  I  St  of  September  to  apply  the  galvano-cautery  to  the 
seat  of  the  growth,  so  as  to  completely  destroy  all  abnor- 
mal tissue.  This  practice  I  believe  is  essential  to  pre- 
vent a  recurrence  of  the  growth.  The  patient  neglected 
to  keep  the  appointment  and  I  did  not  see  him  till  Sep- 
tember 17th,  when  I  found  the  wound  entirely  healed 
and  presenting  a  healthy  appearance,  except  a  small  por- 
tion of  the  cicatrix  near  the  posterior  entrance  to  the 
right  nostril,  where  there  appeared  to  be  more  vascu- 
larity and  a  little  more  prominence  than  the  surface  in 
general  exhibited.  I  was  anxious  to  carry  out  my  plan 
of  treatment  without  delay,  and  appointed  the  following 
day  for  that  purpose,  but  I  have  not  yet  been  able  to  se- 
cure the  co-operation  of  the  patient. 


To     FACILrTATE     THE     PASSAGE     OF     THE    CATHETER 

WHEN  THE  Deeper  Portion  of  the  Urethra  is  Espe- 
cially Sensitive. — Dr.  Andrew  H.  Smith,  of  New  York, 
sends  us  the  following  practical  hint :  '*  In  the  absence 
of  actual  stricture  an  undue  sensitiveness  of  the  mem- 
branous portion  of  the  urethra  often  causes  pain  and 
spasm  the  moment  the  catheter  reaches  that  portion  of 
the  canal.  As  the  operation  is  usually  performed,  the 
difficulty  is  increased  by  the  fact  that  the  back  of  the  in- 
strument reaches  the  sensitive  portion  of  the  canal  in  a 
dry  condition,  that  b  to  say,  the  oil  or  other  lubricating 
substance  with  which  it  was  smeared,  has  been  wiped  off 
by  contact  with  the  walls  of  the  urethra  before  the  point 
is  reached  at  which  a  lubricant  is  most  needed.  This 
difficulty  can  easily  be  overcome  in  the  following  man- 
ner :  Immerse  the  catheter  in  oil,  in  such  a  way  that  the 
oil  will  fill  the  lower  third  of  the  instrument.  Then  close 
the  upper  end  with  the  finger,  and  keep  it  closed  until 
the  back  of  the  catheter  reaches  the  sensitive  spot  Then 
remove  the  finger  and  allow  the  oil  to  flow  out  of  the  eye 
of  the  instrument  and  bathe  the  surface  of  the  membrane. 
If,  at  the  same  moment,  the  catheter  is  carried  gently  on- 
ward, it  will  often  enter  the  bladder  as  easily  as  it  has 
passed  the  wider  portion  of  the  urethra." 


A  UNIQUE  GLASS  WOUND. 

Successful  Ligation  of  the  Left  Common  Carotid 
Artery  and  Internal  Jugular  Vein. 

By  R.  M.  stone,  A.M.,  M.D., 

OMAHA,  MBB. 

At  noon,  on  May  8,  1884,  Melvin  S ,  aged  twenty- 
four,  while  assisting  in  the  removal  of  a  plate  glass  4  feet 
by  8  feet,  was  precipitated  into  the  cellar,  the  glass 
following,   and  of  course  being  broken  in  its  descent, 

S jumped  to  his  feet  unaware  that  he  was  injured, 

but  in  the  next  instant  saw  a  stream  of  blood  shooting 
up  from  beneath  his  left  ear.  He  recognized  at  once  that 
his  jugular  vein  was  cut  and  that  he  must  have  assistance 
within  a  very  few  moments  or  perish. 

A  few  days  before  this  occurrence  his  father  and  he 
had  been  discussing  the  question  of  what  to  do  for  a  per- 
son bleeding  from  a  wound ;  Melvin  then  had  said  that 
should  he  see  such  a  case  he  should  jam  his  thumbs  deep 
into  the  wound  and  try  and  hold  the  vessels  till  help 
came.  So  with  rare  presence  of  mind  he  jerked  off  his 
'glove,  pressed  the  ball  of  his  left  thumb  hard  against  his 
neck  below  the  wound,  and  ran  south  some  thirty  or 
forty  feet  to  the  cellar  stairs,  then  north  across  the  street 
to  the  nearest  physician's  office,  not  less  than  three  hun- 
dred feet  from  where  he  fell.  He  ran  so  rapidly  that  his 
father  chasing  him  could  not  catch  him.  Melvin  rushed 
into  the  open  office,  saw  no  one  present,  wildly  tried  the 
inner  doors  in  the  vain  hope  that  Dr.  Swetnam  was  within, 
exclaiming,  "  O  Doctor,  why  are  you  not  here  ?"  and 
again  sta^ered  on  to  the  pavement.  I  happened  to  be 
standing  m  front  of  my  office,  quite  near,  and  saw  a  friend 
across  the  street  frantically  gesticulating  and  beckoning 
me  toward  the  corner.  I  ran  and  soon  saw  Melvin  stag- 
gering, bleeding,  and  gasping,  a  terrible  torrent  of  arterial 
and  venous  blood  pouring  side  by  side  from  his  neck.  I 
thrust  my  thumb  deep  down  into  the  vast  opening  and 
with  my  elbows  turned  him  on  to  his  side  on  the  door-step. 
By  pressure  with  my  right  thumb  on  the  vessels  from 
below,  with  my  left  against  the  base  of  the  skull  being 
able  to  feel  plainly  the  styloid  process,  I  was  able  to 
check  the  flow  almost  entirely.  I  sent  for  assistance  and 
in  a  very  short  time  had  the  gratification  of  seeing  Drs. 
M.  A.  Rebert,  E,  W.  Lee,  and  Geo.  B.  Ayres  at  my  side. 
No  surgeon  was  ever  more  happy  at  the  sight  of  a  silk 
thread  than  I,  when  I  saw  Dr.  Lee  coming  running  with 
one  in  his  hand.  By  this  time  Melvin  was  almost  gone, 
his  face  deathly  white,  eyes  rolled  upward,  jaw  dropped, 
and  he  was  gasping  and  struggling  for  his  apparently  last 
breath.  We  all  had  the  one  thought  that  he  could  not 
live  long  enough  to  permit  ligation. 

The  position  of  the  wound  beneath  the  ear  showed  that 
the  arterial  blood  must  come  from  the  carotid  ;  the  depth 
of  the  wound,  which  admitted  my  left  thumb  over  two 
inches,  the  fact  that  I  could  feel  the  styloid  process  and 
beyond  it,  made  it  probable  that  the  venous  blood  came 
from  both  jugulars.  The  frightful  loss  of  blood,  the  cer- 
tainty that  the  patient  would  die  before  the  severed  ex- 
ternal carotid  could  be  caught  in  the  wound  and  ligated, 
the  possibility  that  the  internal  carotid  was  either  severed 
or  injured  made  it  necessary  to  tie  the  common  carotid ; 
this  and  the  internal  jugular  vein  were  then  ligated  above 
the  omohyoid  by  Geo.  B.  Ayers,  M.D. 

Meanwhile  Dr.  Rebert  had  taken  my  place,  and  thrust 
his  thumbs  into  the  wound.  After  the  ligation  of  the 
carotid,  he  also  observed  that  his  thumb  went  beyond 
the  styloid  process  and  apparently  to  or  near  the  jugular 
foramen,  and  the  slightest  removal  of  the  thumb  from  the 
base  of  the  skull  allowed  a  seemingly  undiminished 
stream  of  blood  to  poiu-  forth. 

We  felt  that  our  patient  was  too  near  death  to  allow 
us  to  search  for  the  distal  ends  and  ligate,  and  that  a  com- 
press soaked  in  dilute  Monsell's  solution  was  our  only 
resource.  A  pledget  of  cotton,  followed  by  layers  of 
sheet-lint,  were  quickly  placed  in  position  and  the  hem- 
orrhage was  completely  arrested.    Several  other  fiace  and 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


457 


•scalp  wounds  were  sewn  up  while  awaiting  a  vehicle  to 
carry  Melvin  home. 

The  operation  had  taken  place,  fortunately,  in  the  open 
air,  with  the  best  of  light  and  air,  except  as  interfered 
with  at  times  by  the  anxious  hundreds  who  stood  watching. 
The  father  had  sat  holding  his  son's  hand  during  the 
trying  ordeal,  and  Melvin  had  gone  through  with  it  most 
bravely,  answering  once  or  twice  as  we  spoke,  fearing  he 
was  dead,  "All  right  yet,  father,  hold  my  hand."  He 
told  me  afterward  that  the  operation  gave  him  no  pain, 
that  the  condition  following  the  loss  of  blood  was  that  ojf 
anaesthesia.  A  stimulant  had  been  given  and  the  pulse, 
which  was  at  times  very  feeble  and  almost  imperceptible, 
became  fuller  and  stronger,  and  he  bore  the  ride  home 
remarkably  well.  Melvin  had  shown  so  much  pluck, 
judgment,  and  ^vitality  that,  though  we  dared  not  think 
he  had  a  ghost  of  a  chance  for  final  recovery,  we  could 
not  help  the  thought  that  if  any  one  could  recover  from 
such  an  injury  he  was  the  one. 

Though  our  patient  had  passed  safely  through  one  of 
the  greatest  dangers  that  ever  befell  a  man,  yet  we  knew, 
and  he  soon  learned  it  too,  that  he  must  face  the  other 
dangers  of  secondary  hemorrhage  and  pyaemia,  none  the 
less  to  be  feared. 

Melvin  rallied  within  two  hours,  by  the  aid  of  hot  bot- 
tles, became  warm,  and  had  a  fair  pulse  of  76.  He  re- 
ceived quinia,  gr.  iij.,  and  morph.,  gr.  one-eighth,  every 
two  hours  ;  and  whiskey,  |  j.,  and  a  glass  of  ^milk  every 
hour.  We  crowded  the  mUk  to  the  amount  of  a  gallon 
a  day,  so  as  to  make  up  as  rapidly  as  possible  the  loss 
of  blood.  By  7  p.m.  reaction  had  well  taken  place,  the 
heart's  action  was  strong,  his  voice  clear  and  strong,  the 
milk  had  been  assimilated  and  we  suspended  the  drugs 
mentioned  and  gave  fl.  ext.  ergot,  tTlxv. ;  sodium  bromide, 
gr.  XV.,  every  three  hours  instead.  We  continued  these 
drugs  for  their  action  on  the  circulation  at  increasing 
intervals  for  four  days,  suspending  them  as  we  saw  in- 
dication of  beginning  strangury,  caused  by  the  ergot, 
which  ceased  very  soon  upon  its  withdrawal.  I  have  a 
very  fVequent  record  of  the  pulse  and  temperature  up  to 
convalescence,  but  it  would  onljr  be  tedious  to  insert  it ; 
suffice  it  to  say  that  his  morning  temperature  was  be- 
tween 99i°  and  100**,  uniformly  for  twenty  days,  and  his 
pulse  between  70  and  80 ;  his  evening  temperature 
was  between  looj**  and  loi**,  uniformly  for  twelve  days, 
except  on  one  occasion,  the  night  of  the  seventh  day, 
when  it  reached  ioi}°,  while  his  evening  pulse  was  82 
to  84  usually,  rising  to  96  and  100  on  three  occasions 
only. 

Besides  the  medicines  mentioned  I  gave  our  patient 
from  five  to  ten  grains  of  quinia,  with  an  equal  amount  of 
lactopeptine,  daily  during  the  first  two  weeks,  except  on 
the  night  of  highest  temperature,  when  we  gave  fijfteen 
grains.  I  gave  him  one-eighth  grain  of  morphia  twice  or 
thrice  daily  by  the  ^nouth  for  three  days,  and,  after  that, 
from  one-eighth  to  one-fourth  grain  hypodermatically  from 
thrice  to  once  daily  during  the  next  fifteen  days. 

The  margins  of  the  compress  were  kept  sprinkled  with 
Wyeth's  finely  powdered  boracic  acid  until  pus  began  to 
flow  from  beneath,  when  the  compress  and  margins  were 
thoroughly  and  almost  constantly  irrigated  with  a  solution 
of  the  bichloride  of  mercury  i  to  2,000  or  i  to  4,000. 
While  irrigation  was  not  going  on  and  during  sleep  a 
piece  of  sheet-lint,  previously  soaked  in  the  same  solu- 
tion, was  laid  over  the  wound.  Hunyadi  Janos  water 
was  used  internally,  and  rectal  injections  of  warm  water 
with  glycerine  and  ox-gall  added  to  counteract  the  consti- 
pation caused  by  a  milk  diet 

Our  patient's  stomacfi  remained  in  excellent  condition 
during  the  whole  time ;  he  drank  and  assimilated  large 
quantities  of  milk  and  two  egg-nogs,  with  a  little  sherry 
or  port  wine  in,  daily.  Owing  to  the  head  bandage  over 
the  compress  his  position  was  necessarily  a  constrained 
one,  and  yet  he  rested  well  every  night  and  was  delirious 
but  a  few  times,  and  only  then  on  waking ;  he  suffered 
from  headache  on  the  third  and  fourth  days  only. 


During  the  ten  days  following  the  accident  I  watched 
most  anxiously  and  often  at  the  bedside,  dreading  the  ap- 
pearance of  secondary  hemorrhage,  and  had  the  pleasure 
of  seeing  this  dangerous  period  pass  without  the  slightest 
trouble  from  this  source,  or  the  other  of  pyaemia. 

On  the  third  day  there  was  pus  at  the  wound  of  liga- 
tion, but  no  moisture  whatever  at  the  margins  of  the  com- 
press. On  the  sixth  day  I  had  the  pleasure  of  a  visit 
from  my  venerable  friend,  Dr.  Louis  Bauer,  Dean  of  the 
St.  Louis,  Mo.,  College  of  Physicians  and  Surgeons,  and 
we  were  all  very  glad  of  the  privilege  of  his  counsel. 
His  views  as  to  the  necessity  of  then  cutting  the  bandage 
over  the  compress,  loosening  thus  the  irksome  pressure, 
and  the  very  gradual  removal  day  by  day  of  the  layers  of 
the  lint  compress  coincided  with  our  own,  and  this  was 
done.  He  assured  us  that  the  plug  in  ihs  ends  of  the 
vessels  must  be  well  organized,  and  we  had  nothing  to 
fear  in  the  very  cautious  removal  of  the  compress.  On 
the  seventh  day  pus  began  to  flow  quite  freely  from  be- 
neath the  compress,  and  from  this  time  on  the  bichloride 
solution  was  most  assiduously  used ;  on  this  day  occurred 
the  only  notable  rise  of  temperature,  and  I  greatly  feared 
that  pyaemia  had  indeed  begun;  the  temperature  and 
pulse,  however,  quickly  fell,  the  delirium  subsided,  and 
we  had  no  further  cause  for  uneasiness. 

Little  by  little  I  had  removed  the  layers  of  the  com- 
press, which  allowed  better  irrigation,  and  on  May  1 7th 
there  remained  but  the  pledget  of  cotton,  loose,  easily 
moved,  and  adherent  in  a  few  spots  only.  Melvin  had 
now  passed  nine  full  days,  had  no  fear  whatever  of  sec- 
ondary hemorrhage,  was  jovial  and  happy,  and  kept  ask- 
ing for  a  cigar. 

On  May  23d,  the  fifteenth  day,  the  cotton  pledget 
came  away ;  though  a  very  little  traction  could  have  re- 
moved it  at  any  time  since  May  1 7th  it  was  deemed  best 
not  to  remove  it  and  thereby  possibly  endanger  the  in- 
tegrity of  the  clots  in  the  mouths  of  the  vessels.  We 
now  could  see  the  full  size  of  the  cavern,  though  granu- 
lation had  been  goin^  on  for  some  days ;  it  was,  by  care- 
ful measurement,  i^  inch  in  depth  and  2^  inches  wide  at 
the  surface,  tapering  to  ^  or  |  inch  in  width  at  the  bot- 
tom ;  on  the  front  wall  of  the  cavern,  near  the  bottom, 
could  be  seen  and  felt  the  styloid  process.  On  May  25th 
a  photograph  was  taken,  from  which  the  accompanying 


irif^- 


woodcut  was  made.  The  walls  of  the  cavern  were  lined 
with  the  most  beautiful  and  healthy  granulations,  which, 
under  the  irrigations,  remained  so  and  very  rapidly  filled 
the  cavity.  On  June  5th  the  cavity  was  reduced  to  three- 
fourths  of  an  inch  in  depth  and  width,  and  on  June  27  th 
a  fine  probe  could  hardly  be  inserted  in  the  cavity,  and 
only  a  slightly  more  deep  than  normal  depression  existed 
beneath  the  ear.  We  had  expected  a  salivary  fistula  to 
remain,  since  the  parotid  gland  was  laid  wide  open,  but 
it  did  not. 

On  June  12th,  the  thirty-sixth  day,  I  removed  one  of 
the  ligatures.  The  other,  which  had  previously  resisted 
quite  strong  traction,  was  removed  on  the  seventy-ninth 
day. 

On  June  24th  Melvin  was  able  to  come  down  town 
and  receive  the  congratulations  of  the  many  friends  who 
had  often  enquired  about  his  condition. 

What  condition  now  existed?  The  facial  nerve  hav- 
ing been  severed,  our  patient  is  unable  to  frown  with  the 


458 


THE  MEDICAL  RECORD. 


[October  25.  1884. 


left  side  of  his  forehead,  cannot  close  his  left  eye,  has 
no  motion  of  the  muscles  of  the  left  cheek,  his  tongue 
points  far  to  the  left  when  protruded,  the  left  angle  of 
his  mouth  is  one-half  or  three-fourths  of  an  inch  beneath 
the  right,  and  he  is  one  of  the  few  unfortunate  individu- 
als who  literally  laugh  out  of  one  corner  of  their  mouths. 
He  has  suffered  considerable  inconvenience  from  his 
exposed  cornea ;  lachrymation  has  been  profuse  two  or 
three  times  from  irritation,  and  this  will  no  doubt  prove 
the  most  serious  source  of  trouble.  He  is  acquiring  the 
habit  of  brushing  the  cornea  with  his  upper  lid,  and 
hopes  in  this  way  to  get  along,  but  I  fear  that  it  will  not 
answer,  and  sloughing  of  the  cornea  may  result. 

There  are  a  few  features  of  the  case  that  are  unusual, 
and  I  think  worthy  of  special  mention.  Superficial  glass 
wounds  are  numerous,  and  wounds  involving  the  radial 
and  ulnar  arteries  and  tlie  palmar  arches  are  quite  so, 
but  I  cannot  find  recorded  a  case  of  a  wound  of  the 
carotid  region  made  by  glass.  This  was  also  one  of  the 
rare  cases  where  distal  ligation  was  absolutely  out  of 
the  question ;  any  attempt  in  that  direction  would  cer- 
tainly have  been  fatal,  and  no  surgeon  of  good  judgment 
would  for  a  moment  have  thought  of  it. 

But  the  most  interesting  and  unique  feature  about  the 
case  seems  to  me  to  be  that  the  internal  jugular  vein 
was  probably  shaved  off  close  to  its  emergence  from  the 
jugular  foramen,  and  if  so,  rendered  distal  ligation  abso- 
lutely impossible.  An  autopsy  alone  could  demonstrate 
this  to  have  been  the  fact ;  but  the  great  depth  of  the 
wound,  the  fact  that  after  ligation  of  the  carotid  the 
slightest  removal  of  the  thumb  from,  at,  or  very  near 
the  foramen,  was  followed  by  a  terrible  welling  up  of 
venous  blood,  incline  us  to  believe  that  this  was  the 
case.  I  can  find  but  one  similar  case  on  record,  that  of 
Kochers,  found  in  the  "  International  Encyclopedia  of 
Surgery,"  vol.  iii.,  p.  504.  He  had  a  case  of  a  stab  be- 
tween the  fifth  and  sixth  cervical  vertebrae.  He  says 
that  he  removed  clots  and  seized  "  the  bleeding  point 
with  long  forceps,  but  it  was  impossible  to  tie  any  vessel 
as  the  ligature  had  nothing  to  grip.** 

Whatever  was  the  case  as  regards  this  point,  I  trust 
the  history  will  prove  of  interest  and  value,  and  worthy 
of  record. 


CEREBRAL    LOCALIZATION— THE    CENTRES 
FOR  VISION. 

By  PHILIP  ZENNER,  A.M.,  M.D., 

aNCINNATI,  O. 

(Continued  from  p.  345.) 

In  the  three  preceding  papers  we  have  given  the  data 
from  which  we  concluded  that  a  limited  area  of  the  cortex 
in  the  posterior  part  of  the  hemispheres  is  in  close  rela- 
tion with  the  retinae,  this  area,  therefore,  possessing  visual 
functions.  We  wish  now  to  map  out,  as  nearly  as  may 
be,  the  more  precise  relationship  of  the  visual  area  to  the 
retinae  in  man,  and  to  consider  some  other  questions, 
which  deal  more  closely  with  the  exact  functions  of  the 
cortical  centres. 

Relation  of  optic  tracts  to  retina. — We  must  premise 
the  consideration  of  relationship  of  cortex  and  retina  by 
that  of  the  optic  tracts  to  the  retinae,  for,  as  will  sub- 
sequently appear,  the  optic  tract  is,  probably,  only  in 
relationship  with  the  hemisphere  of  the  same  side,  and, 
therefore,  knowing  its  relationship  to  the  retinae,  we  will 
already  have  acquured  knowledge  on  the  final  question — 
the  relation  of  cortical  centre  and  retina. 

In  quite  a  number  of  instances  after  destruction  of  one 
eye,  and  atrophy  of  the  corresponding  optic  nerve,  atrophy 
of  fibres  in  both  optic  tracts  was  observed.  This  atrophy 
in  the  optic  tracts,  always  involving  only  a  part  of  each, 
is  usually  determined  with  some  difficulty,  and  there  is 
consequently  some  variance  in  the  reports  of  the  extent 
to  which  each  tract  degenerates.     Mauthner,^  after  care- 

Gehim  und  Au^  p.  437. 


fully  examining  all  the  reported  cases,  concludes  that  the 
larger  number  of  fibres  of  each  optic  nerve  cross  over 
to  the  opposite  optic  tract,  while  a  smaller  number  of 
fibres  enter  the  tract  of  the  same  side,  the  proportion  of 
crossed  to  uncrossed  fibres  being  as  three  to  two. 

A  number  of  cases  have  been  reported  where  hemian- 
opia  followed  lesions  of  an  optic  tract.  In  most  of  them 
the  entire  tract  was  not  destroyed  or  there  were  other 
complications,  so  that  they  can  not  be  utilized  for  our 
present  purpose.  But  in  one  instance,  a  case  of  Gowers/ 
there  was  complete  degeneration  of  one  optic  tract  with- 
out involvement  of  any  other  important  part,  so  that  the 
case  answers  our  purpose  admirably.  In  this  case,  ac- 
cording to  Gowers'  report,  there  was  **a  blindness  in  the 
symmetrical  halves  of  both  fields  of  vision,  which  reached 
in  each  one  to  the  median  line." 

There  is  an  apparent  discrepancy  between  the  clinical 
manifestations  in  Gowers'  case,  where  blindness  reaches 
to  the  median  line,  and  the  pathological  observations 
that  more  fibres  of  the  optic  nerve  pass  into  the  opposite 
optic  tract  than  into  that  one  of  the  same  side.  But  this 
discrepancy  is  only  apparent  For  a  vertical  line  pass- 
ing through  the  point  of  fixation  does  not  divide  the 
retina  into  two  equal  halves.  The  nasal  segment  is 
larger  than  the  temporal,  and  therefore  receives  a  larger 
number  of  fibres  from  the  optic  nerve. 

Relation  of  visual  area  to  retina. — What  has  already 
been  learned  of  the  relations  of  visual  areas  and  retins 
in  the  lower  animals,  as  well  as  the  relationship  of  optic 
nerves  and  tracts  just  mentioned,  naturally  lead  us  to 
expect  that  in  man  the  visual  area  of  each  hemisphere  is 
in  relation  with  one  half  of  each  eye.  Observations  in 
animals  lead  to  this  belief,  because  we  find  that  the 
higher  the  animal  the  more  nearly  each  hemisphere  is  in 
equal  relation  with  both  retinae.  Thus,  in  rabbits  one 
visual  area  is  almost  alone  related  to  the  opposite  eye. 
In  dogs  about  one-third  of  the  visual  area  is  devoted  to 
the  eye  of  the  same  side ;  while  in  monkeys,  according 
to  Munk,  each  visual  area  is  devoted  to  one-half  of  both 
eyes. 

The  direct  observations  in  man  seem  to  justify  this  ex- 
pectation. Of  Baumgartner's  case  it  is  expressly  stated 
that  the  hemianopia  reached  to  the  point  of  fixation.  Of 
Curschman's,  Marchand's,  and  Westphal's  cases  it  was 
said  that  there  was  complete  hemianopia.  In  other  in- 
stances, as  cases  of  Nothnagel,  Wernicke,  and  Stenger, 
the  hemianopia  did  not  reach  to  the  point  of  fixation  and 
the  loss  of  the  field  of  vision  was  more  extensive  in  one 
e^e  than  in  the  other.  But  in  the  latter  instances  the 
visual  area  of  one  hemisphere  was,  apparently,  not  alto- 
gether destroyed.  So  that  we  may  safely  conclude  from 
the  above  cases  that  each  area  is  in  relation  with  one-haI( 
or  almost  one-half"  of  both  retinae. 

One  of  the  cases  given  in  the  previous  paper,  that  of 
Nieden,  seems  to  throw  light  on  the  more  exact  relation- 
ship of  visual  areas  and  retinae,  and  to  point  to  the  exist- 
ence of  the  same  relationship  in  man  as  Munk  bad 
observed  in  dogs,  that  is,  that  the  external  portion  of  the 
visual  area  of  one  hemisphere  is  in  relation  with  the  tem- 
poral half  of  the  retina  of  the  same  side,  while  the  median 
portion  of  the  visual  area  is  in  relation  with  the  nasal  half 
of  the  opposite  retina.  For  in  Nieden' s  patient  the  orig- 
inal injury  apparently  involved  but  a  small  part  of  the 
occipital  lobe,  that  nearest  the  longitudinal  fissure,  and 
there  was  at  that  time  paralysis  of  the  nasal  portion  of 
the  opposite  retina.  At  a  later  period,  when  probably 
the  process  of  cicatrization  had  produced  some  changes 
in  the  part  of  the  occipital  lohe  l)ang  more  extemaUj, 
there  was  also  paralysis  of  a  part  of  the  temporal  segment 
of  the  retina  on  the  same  side. 

Single  vision  with  double  retinal  images. — Wernicke,' 
taking  as  a  basis  that  each  visual  area  is  devoted  to  the 
corresponding  halves  of  both  retinae,  and  that  the  more 

1  Centralblatt  f.  d.  Med.  A^scnschaften,  1878,  No.  31. 
*  The  reason  for  thus  modifying  the  statoneat  will  appear  lata-. 
.*  Gehimkrankheiten,  vol.  i.,  p.  236. 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


459 


proximate  relationship  in  man  is  the  same  as  Munk  had 
found  it  to  be  in  dogs,  has  thus  explained  the  existence 
of  sinde  vision  with  double  retinal  images.  The  ex- 
planation is  so  beautiful,  and,  withal,  so  simple  and 
natural,  that  it,  in  itself,  tempts  us  to  accept  as  true  the 
premises  upon  which  it  is  based. 

According  to  these  premises  the  median  half  of  the 
right  visual  area  is  devoted  to  the  median  or  nasal  half 
of  the  left  retina,  while  the  temporal  half  of  the  right  vis- 
ual area  is  devoted  to  the  temporal  half  of  the  right 
retina ;  and  in  each  instance  the  segment  of  the  visual 
area  is  so  related  to  the  segment  of  the  retina  that  the 
central  part  of  the  latter  is  related  to  the  central  part  of 
the  visual  area,  its  peripheral  parts  to  the  peripheral  parts 
of  the  latter. 

This  relationship,  as  well  as  the  projection  of  the 
retinal  images  upon  the  visual  areas,  will  become  more 
perspicuous  by  attention  to  the  accompanying  diagram : 
op  represents  the  right,  m  n  the  left  retina;  WPthe 
right,  m  0  the  left  visual  area ;  c  the  macula  lutea.  c  n, 
the  nasal  half  of  left  retina,  is  projected  upon  C  N^  the 
median    half  of    right 

visual  area,  while  c  m  \~  R 

is  projected  upon  CMy 
c  being  projected  upon 
C,  and  m  and  n  upon 
ifand  N  respectively. 
As  Ct  the  most  sensitive 
part  of  the  retina,  is 
projected  upon  C,  the 
central  part  of  visual 
area,  the  latter  is  the 
most  sensitive  part  of 
the  visual  area. 

act  and  a!  c  V  rep- 
resent the  two  retinal 
images  of  an  observed 
object.  The  corre- 
sponding half  of  each 
image  will  be  projected 
upon  one  visual  area. 
Thusr  b  and  c  b'  are 
projected  upon  C  B 
and  C  B\  the  central 
part  of  the  image  being  projected  upon  the  centre  of 
die  visual  area,  its  peripheral  parts  in  the  more  peripheral 
parts  of  the  visual  area,  each  point  being  there  doubly 
represented  on  each  side  of,  and  probably  at  equal  dis- 
tances from  the  centre.  This  double  representation  ap- 
pears in  consciousness  as  one,  because  the  corresponding 
parts  are  very  intimately  bound  together  by  associating 
fibres. 

Crossed  amblyopia  with  cerebral  lesions, — The  above 
conclusions  are  not  altogether  in  accordance  with  the 
views  of  two  eminent  men,  both  strenuous  adherents  of 
the  present  theories  of  cerebral  localization,  Charcot  and 
Ferrier,  I  refer  to  the  clinical  observations  of  the  one, 
and  the  physiological  experiments  of  the  other.  Their 
observations  and  results  deserve  careful  attention,  be- 
cause opposing  views  in  such  high  quarters  are  likely  to 
throw  doubt  on  the  whole  subject  of  localization. 

From  clinical  observations  in  some  cases  of  hemianaes- 
thesia  and  amblyopia  in  one  eye  Charcot  concluded  that 
certain  lesions  of  the  internal  capsule  caused  blindness 
in  the  opposite  eye.  Accepting  the  semidecussation  of 
the  optic  nerves  in  the  chiasma,  he  now  constructed  a 
new  scheme  of  the  cause  and  final  distribution  of  the 
optic  nerves.  According  to  this  scheme  those  fibres  of 
the  optic  nerve  which  do  not  cross  over  at  the  chiasm, 
but  pass  into  the  optic  tract  of  the  same  side,  do  cross 
over  and  enter  into  the  other  side  of  the  brain  at  some 
point  beyond  the  corpora  quadrigemina.  He  thus  ex- 
plained that,  while  lesions  of  one  optic  tract  would  pro- 
duce hemianopia,  lesions  of  the  internal  capsule  produced 
a  crossed  amblyopia. 

When  it  became  subsequently  known  that  lesions  of 


Diagram  c£  the  Projective  of  Retinal.Im- 
ages  on  d^eVisiial  Areas. 


the  cortex  of  one  hemisphere  caused  homonymous  latend 
hemianopia,  this  scheme  being  insufficient  to  explain 
such  conditions,  Grasset  *  modified  it  by  a  third  crossing 
of  the  optic  nerve-fibres  at  a  point  beyond  the  internsd 
capsule. 

The  original  scheme  of  Charcot  already  appeared 
sufficiently  unnatural  to  cast  doubt  upon  its  correctness, 
but  that  of  Grasset  is  so  very  artificial  as  to  rob  it  of 
all  credence. 

In  this  diflSculty  we  are  led  to  inquire  whether  Char- 
cot's premises,  in  the  first  instance,  were  correct,  whether 
it  is  true  that  lesions  in  the  posterior  part  of  the  internal 
capsule  cause  blindness  in  the  opposite  eye,  and  that, 
therefore,  all  the  fibres  of  one  optic  nerve  pass  through 
the  opposite  internal  capsule. 

Many  of  Charcot's  observations  were  on  hysterical 
cases.  These  we  may  altogether  ignore,  both  because 
the  seat  of  the  trouble  is  unknown  and  because,  in  these 
instances,  the  visual  disturbances  are  not  always  of  the 
same  character. 

Of  the  cases  in  which  there  were  cerebral  lesions,  in 
some  the  diagnosis  crossed  amblyopia  doubtless  rested 
upon  erroneous  observations.  In  the  previous  paper  we 
called  attention  to  the  fact  that  it  is  common  for 
those  suffering  with  hemianopia  to  state  and  to  believe 
that  they  are  blind  in  one  eye.  They  are  often  much 
surprised  to  learn,  after  a  careful  examination  has  been 
made,  that  both  eyes  are  alike  affected.  But  there  are 
other  cases  to  which  these  objections  do  not  apply  and 
which  must  therefore  be  examined  more  carefully. 

The  first  two  cases  of  this  kind,  with  post-mortem  re- 
sults, were  reported  by  Tiirck."  But,  inasmuch  as 
there  was  no  evidence  that  a  careful  examination  of 
vision  was  made,  these  cases  may  be  passed  by.  In 
Bernhardt's  *  case  there  was,  with  right  hemianaesthesia 
complete  blindness  in  the  right  eye,  but  there  was,  at  the 
same  time,  concentric  narrowing  of  the  field  of  vision  in 
the  left  eye, 

A  patient  of  Pitres  *  had  left  hemianaesthesia  and  hemi- 
plegia and  amblyopia  in  the  left  eye.  But  in  this  case 
there  was  also  defective  vision  in  the  right  eye.  In  both 
eyes  there  was  concentric  contraction  of  the  field  of  vis- 
ion.    There  was  also  discoloration  of  both  optic  nerves. 

So  in  these  two  cases  where  post-mortem  examination 
was  made  (the  same  seems  to  be  true  in  similar  instances 
without  post-mortem  results,  whenever  careful  examina- 
tion was  made)  there  was  not  only  a  crossed  amblyopia 
but  also  impairment  of  vision  in  the  eye  of  the  same  side ; 
so  that  these  cases  do  not  sustain  the  original  statements 
of  Charcot,  or  support  his  scheme  of  the  course  of  the 
optic  nerve-fibres. 

There  is  only  one  case,  so  far  as  I  know,  which  directly 
supports  this  scheme,  that  is  one  reported  by  Mueller.* 
In  diis  case  a  small  lesion  was  found  in  the  posterior 
part  of  the  left  internal  capsule,  and,  during  life,  there 
was  on  the  right  side  slight  paralysis  and  complete 
anaesthesia,  loss  of  taste,  smell,  and  hearing  in  the  same 
side  and  amblyopia  in  the  right  eye.  It  was  expressly 
stated  that  vision  in  the  left  eye  was  normal,  there  be- 
ing no  narrowing  of  the  field  of  vision. 

Wernicke,*  in  reviewing  this  case,  states  that  the  re- 
porter was  evidently  influenced  by  Charcot's  previous 
writings,  and  does  not  hesitate  to  pronounce  the  descrip- 
tion of  the  visual  disturbances  to  be  due  to  faulty  observa- 
tions. This  appears  to  be  a  very  summary  way  of 
disposing  of  what  are,  apparently,  carefully  recorded 
observations,  but  yet  it  is  not  altoj;ether  unjustifiable. 
Charcot  has  acknowledged  that  his  first  observations 
were  incorrect,  that  visual  disturbances  could  always  be 
detected  in  the  other  eye,  and  the  same  have  been  the 
observations  of  others  in  similar  instances.     But  of  much 


1  Gazette  Hebdomadaire,  1883,  p.  205. 

*  Nothnagel :  Topische  Dia^ttic,  p.  305.  | 

*  Berliner  Klin.  Wochenschnft,  187^,  No.  36. 

*  Wernicke  :  Gehimkrankheiten,  vol.  ii,  p.  82. 
«  Berliner  Klin.  Wochenschrift,  1878,  No.  20.  ^ 

*  Gehimkrankheiten,  vol.  ii.,  p.  aoa. 


460 


THE   MEDICAL  RECORD. 


[October  25, 1884. 


more  consequence  is  the  fact  that  a  number  of  cases 
have  been  reported,  where,  while  the  post-mortem  ex- 
amination revealed  destruction  of  the  posterior  part  of 
the  internal  capsule,  visual  disturbances  of  the  kind  just 
mentioned  (crossed  amblyopia)  were  not  found.  Such 
are  the  cases  of  Prevost,*  Pooley,*  Dreschfeld,"  Senator 
and  Wernicke,*  and  Vetter/  In  all  of  these  cases 
there  was  hemiansesthesia  on  the  opposite  side. 

In  addition  to  the  above  there  are  other  cases  of  hemi- 
anaesthesia  where  the  description  of  the  autopsy  leaves 
us  in  doubt  whether  the  internal  capsule  was  injured ; 
and  others  where  the  symptoms  lead  us  to  believe  that 
there  was  a  lesion  of  the  internal  capsule ;  in  all  of  which 
there  was  no  crossed  amblyopia. 

These  instances  are  quite  sufficient  to  satisfy  us  that 
lesions  of  the  internal  capsule  which  cause  loss  of  gen- 
eral sensation  in  one  half  of  the  body,  and  may  also 
affect  all  the  special  senses,  do  not  directly  produce 
crossed  amblyopia,  and  that  Charcot's  scheme  is  not  cor- 
rect. But  nevertheless  it  must  be  put  down  as  a  singu- 
lar fact  that  lesions  in  the  neighborhood  of  the  internal 
capsule  should  frequently  be  accompanied  by  visual  dis- 
turbances chiefly  in  the  opposite  eye.  Nothing  that  has 
been  above  said  explains  their  occurrence,  but  it  is  to 
be  hoped  that  this  obscure  point  may  be  cleared  up  by 
careful  observations  in  the  future. 

Experiments  of  Ferrier, — We  must  now  speak  of  the 
experiments  of  Ferrier.  They  are  mentioned  here,  in- 
stead of  with  the  other  physiological  data,  because  he 
has  recently  *  attempted  to  bring  them  into  accordance 
with  the  above  teaching  of  Charcot. 

Ferrier's  experiments  were  made  on  monkeys ;  his  con- 
clusions (only  those  relating  to  vision  are  here  men- 
tioned) are  the  following :  *  i.  Destruction  or  bodily 
removal  of  one  or  both  occipital  lobes  almost  to  the 
parieto-occipital  fissure  produces  no  discernible  dis- 
turbance of  vision.  2.  Complete  destruction  of  one 
angular  gyrus  produces  blindness  in  the  opposite  eye, 
which  is  of  only  a  few  hours'  duration.  If  after  a  few 
weeks  the  second  angular  gyru$  is  destroyed,  there  is 
only  very  slight  or  transient  visual  disturbance.  But  if 
both  angular  gyri  are  destroyed  at  the  same  time,  there 
is  total  blindness  in  both  eyes  of  a  few  days'  duration. 
3.  Destruction  of  the  occipital  lobe  and  angular  gyrus 
on  one  side  produces  homonymous  lateral  hemianopia. 
But  after  a  week  or  more  there  are  evidences  of  vision 
on  both  sides.  4.  Destruction  of  both  occipital  lobes 
and  both  angular  gyri  causes  total  and,  apparently,  per- 
manent blindness,  but  the  presence  of  one  angular  gyrus 
or  one  occipital  lobe  is  sufficient  for  vision  in  both  eyes. 

Ferrier  supposes  that  each  angular  gyrus  is  connected 
with  the  central  portion  of  both  retinae,  while  each  occip- 
ital lobe  is  in  relation  with  the  corresponding  halves  of 
both  retinae.  He  believes  that  crossed  amblyopia  at- 
tends lesions  of  the  internal  capsule,  because,  in  such 
instances,  those  fibres  are  destroyed  which  pass  from  the 
angular  gyrus  to  the  opposite  eye.  How  unsatisfactory 
as  well  as  arbitrary  are  these  conclusions  it  is  scarcely 
necessary  to  mention. 

The  above  experimental  results  are  very  puzzling,  and 
seem  to  be  altogether  at  variance  with  what  we  have 
been  taught  by  other  physiologists,  as  well  as  with  what 
we  have  learned  from  pathological  observations  on  man, 
for  instance,  his  observation  that  destruction  of  an  entire 
visual  area  produces  only  transient  disturbance,  and 
clinical  observations  of  permanent  hemianopia  following 
destruction  of  one  visual  area.  It  seems  much  easier  to 
believe  that  the  apparent  disappearance  of  visual  dis- 
turbances in  Ferrier's  monkeys  was  due  to  parts  of  the 
visual  area  (gray  matter  of  the  sulci,  on  the  median  sur- 
face of  the  brain,  etc)  being  retained,  and  to  the  ex- 
treme alertness  and  sagacity  of  those  animals. 


1  Wilbrand  :  Ueber  Hemianopsie,  p.  133.       *  Archiv.  C  Ophth.,  voL  v.,  p.  148. 
s  Brain,  vol.  iv.,  p.  ^3.  <  Gehirnkrankheiteii,  voL  iL,  p.  70. 

»  Deut.  Achiv.  f.  Klin.  Med.,  x88j,  p.  507.      •  Brain,  vol.  iiL,  p,  467.  ., 
""  Ibid.,  p.  430. 


There  are  two  of  Ferrier's  statements  which  cannot 
be  so  summarily  treated,  and  which  will,  perhaps,  require 
future  and  more  careful  observations  for  a  positive 
answer ;  these  are,  that  the  visual  areas  include  more 
than  the  occipital  lobes  (also  the  angular  gyri),  and  that 
each  visual  area  is  in  relation  with  the  central  part  of 
both  retinae. 

Luciani  and  Tamburini  *  also  include  the  angular 
gyrus  in  the  visual  area,  but,  like  Munk,  they  believe 
each  visual  area  to  be  in  relation  with  only  one-half  of 
both  retinae.  Munk  "  attributes  the  visual  disturbances 
obtained  by  these  experimenters  after  destruction  of  the 
angular  gyrus  to  direct  involvement  of  the  optic  radia- 
tions, which,  according  to  Wernicke,  pass  immediately 
beneath  the  angular  gyrus. 

Observations  on  man  do  not  oppose  Ferrier's  views, 
for  the  disease  in  all  instances  was  too  extensive  to  say 
that  the  symptoms  were  produced  by  involvement  of  the 
occipital  lobe  alone. 

The  second  proposition  already  noted,  that  each 
visual  area  is  in  relation  with  the  central  part  of  both 
retinae,  seems  to  find  some  support  in  clinical  observa- 
tions. We  have  mentioned  above  the  clinical  observap 
tions  which  led  us  to  conclude  that  each  visual  area  is 
in  relation  with  one-half  or  almost  one-half  of  both 
retinae.  The  statement  was  thus  modified  for  several 
reasons.  Though  several  cases  are  recorded  where  the 
hemianopia  reached  to  the  point  of  fixation,  such  ob- 
servations should  be  received  in  a  guarded  manner,  for 
it  is  very  difficult  to  mark  out  the  exact  limits  of  vision. 
In  a  case  of  right  hemianopia,  reported  by  myself^'  a 
skilful  specialist  stated  that  the  hemianopia  reached  to 
the  point  of  fixation,  though  in  several  very  careful  ex- 
aminations made  by  myself,  with  the  assistance  of  a 
medical  friend,  a  very  slight  curving  of  the  dividing  line 
toward  the  affected  side  was  positively  determined.  Be- 
sides, there  are  a  number  of  cases  with  lesions  of  the 
occipital  lobe  where  the  hemianopia  did  not  reach  to  the 
point  of  fixation.  In  one  of  them,  that  of  Hosch,*  ap- 
parently the  whole  of  one  visual  area  was  destroyed. 
In  others,  it  is  true,  an  entire  visual  area  did  not  appear 
to  be  destroyed,  so  that  we  might  thus  account  for  the 
visual  defect  on  one  side  not  being  complete.  Yet  it  is 
a  striking  fact  that,  in  such  instances,  just  the  central 
part  of  the  field  was  retained. 


The  Legal  Enforcement  of  Study  at  Home.— A 
novel  suit,  involving  health  questions,  has  recently  been 
decided  in  one  of  the  English  Appellate  Courts.  A 
teacher  in  one  of  the  public  schools  prescribed  certain 
lessons  which  were  to  be  learned  at  home,  and  when  these 
were  not  satisfactorily  committed  to  memory  a  difficulty 
arose  between  the  teacher  and  scholar,  which  is  not  fully 
detailed,  but  which  gave  rise  to  the  charge  of  assault  and 
battery  against  the  teacher.  The  determination  of  the 
charge  of  assault  does  not  appear,  but  the  court  where 
the  case  was  originally  tried,  and  the  Appellate  Court, 
both  decided  that  "  home  lessons  set  by  teachers  cannot 
be  enforced."  This  decision  seems  to  hold  that  schoUxs 
cannot  be  held  responsible  for  the  learning  of  lessons 
at  any  other  place  than  the  school-room.  It  can  hardly 
prevent,  however,  teachers  from  giving  lessons  of  such 
length  as  to  require  study  out  of  school  hours,  and  if  they 
are  not  learned  the  scholar's  standing  will  necessarily  be 
lowered.  Such  a  result  will,  of  course,  modify  largely  the 
practical  results  of  the  decision.  The  attention  of  parents 
and  teachers,  here,  as  well  as  in  England,  cannot  be  too 
emphatically  called  to  the  question  whether  the  requi^^ 
ments  of  home  study,  directly  or  indirectly  made,  are  not 
in  general  too  exacting  for  the  proper  development  of  the 
health  of  children. 


1  Cited  by  Ferrier  and  Munk. 

*  Ueber  die  Funcdonen  der  Grosshimrinde,  p.  x«5. 

*  Cincinnati  Lancet  and  Clinic,  April  7,  1883. 

*  Zehnder's  Monatsblatt,  2878,  p.  285. 


October  25,  1884.] 


THE   MEDICAL  RECORD. 


461 


HYDROCHLORATE   OF    COCAINE— EXPERI- 
MENTS AND  APPLICATION. 
By  H.  KNAPP,  M.D., 
fgonsao*  or  ophthalmology,  medical  dbpartmbmt  univbksity  op  thb 

CITY  OF  NEW  YOSK. 

As  soon  as  I  had  read  the  very  remarkable  communica- 
tion on  cocaine,  by  Dr.  H.  D.  Noyes,  in  The  Medical 
Kkcorp,  October   11,   1884,  p.  417,  I  procured  speci- 
mens of  the  new  remedy  from  different  sources — Mr.  F. 
W.  Foucar,  New  York ;  Dr.   K   R.  Squibb,  Brooklyn ; 
and  Messrs.  Eimer  &  Amend,  New  York — and  tried  its 
action  on  myself,  some  members  of  my  family,  and  a  num- 
ber o(  patients.     Since  that  time  some  short  communica- 
tions on  the  same  remedy  have  appeared  by  Drs.  C.  R, 
Agnew,  W.  O.  Moore,  and  J.  L.  Minor  (The  Medical 
Record,  October  18,  1884,  PP-  43^1  439)-     My  obser- 
vations substantially  confirm   the    statements  of  these 
gentlemen.     The  novelty  and  importance  of  the  subject 
may  excuse  the  hasty  publication  of  some  experiments 
and  observations  which  I  will  describe  without  much 
comment  as  they  have  suggested  and  presented  them- 
selves to  me.     As  only  Dr.  Moore  mentions  something 
about  the  substance  itself,  I  looked  up,  in  the  desire  for 
further  information,  sopcke  books  on  pharmaceutical  chem- 
istry.   The  works  which  I  have  consulted  are :  "  The 
U.  S.  Dispensatory,"  thirteenth  edition,  1870,  p.  1591  ; 
the  same,  fifteenth  edition,  1883,   pp.    563-565 ;   and 
through  the  kindness  of  Messrs.  Eimer  &  Amend,  Feh- 
ling's  "  Handwdrterbuch  der  Chemie,"  1875,  vol.  ii.,  pp. 
IS^f  753*   2tnd   Hager's  ''  Handbuch    der    Pharmaceu- 
tischen  Praxis,"  1876,  First  Part,  pp.  903-905.     From 
these  books  I  extract  the  following  pharmacological  notes, 
which  may  not  be  without  interest. 

Cocaine  is  the  alkaloid  of  the  leaves  of  eiythroxylon 
coca  (Lamarck),  a  shrub  growing  wild  and  extensively 
cultivated  in  South  America,  especially  in  Peru  and 
Bolivia.  The  leaves  resemble  those  of  Chinese  tea,  and 
their  action  is  similar  to  that  of  tea  and  coffee.  The 
alkaloid  was  first  isolated  from  them  in  1855  by  Gar- 
deke,  who  gave  it  the  name  erythroxyline ;  but  Dr.  A. 
Niemann,  of  Goslar,  Germany,  was  the  first  to  thoroughly 
investigate  the  leaves  in  i860.  He  gave  the  alkaloid  the 
name  cocaine.  Lossen,  who  followed  in  his  footsteps, 
analyzed  it  and  expressed  its  composition  by  the  follow- 
ing formula :  C„H,^NO^.  "  It  acts  upon  the  lower  ani- 
mals much  as  does  theine.  It  tetanizes  frogs,  or  in  over- 
whelming doses  paralyzes  the  sensory  nerves  and  the 
posterior  columns.  Rabbits  and  dogs  are  killed  by  it 
through  paralysis  of  the  respiratory  centres.  In  proper 
doses  it  elevates  arterial  pressure  by  an  action  upon  the 
vaso-motor  centres  and  the  cardiac-motor  system." 

'*  As  a  nerve-stimulant,  coca  has  been  used  immemo- 
rially  by  the  Peruvian  and  Bolivian  natives.  Its  sus- 
taining powers  have  been  strongly  confirmed  by  various 
observers  both  in  this  country  and  in  Europe  "  (U.  S. 
Disp.). 

Lossen  found  in  the  best  quality  of  coca-leaf  0.04 
per  cent,  of  cocaine ;  inferior  materiad  yielded  only  0.016 
per  cent.  It  dissolves  in  704  parts  of  water,  but  easily 
in  alcohol,  ether,  and  diluted  acids.  Its  salts  are  soluble 
in  alcohol,  not  in  ether.  They  have  a  bitter  taste,  and 
cause  in  the  tongue  a  transient  feeling  of  numbness  at 
the  place  of  contact  (Fehling). 

^  The  coca-leaves  have  been  recommended  for  almost 
all  diseases,  but  the  therapeutic  results  have  proved  un- 
satisfactory and  the  remedy  has  become  obsolete.  The 
action  of  cocaine  is  very  much  like  that  of  atropine,  with 
the  difference  that  it  does  not  dilate  the  pupil.  .  .  . 
Extractum  cocae  is  prepared  like  extractum  absinthii. 
It  is  said  to  have  a  dilating  effect  on  the  pupil "  (Hager). 
Dr.  H.  D.  Noyes  states  in  his  communication  (Medi- 
cal Record,  p.  417,  middle  of  first  column)  :  ''The  solu- 
tion [of  muriate  of  cocaine,  two  per  cent]  caused  no 
irritation  of  any  kind,  nor  did  it  at  all  influence  the  pupil.'' 
Experiments  with  Cocaine  on  the  Eye. — In  my 
first  experiments  with  a  two  per  cent,  solution  upon  pa- 


tients during  various  operations  I  noticed  no  dilatation 
of  the  pupil,  but  trying  it  afterward  on  a  patient  with 
ocular  neuralgia,  and  watching  it  longer,  the  mydriatic 
effect  of  the  drug  was  manifest.  The  same  with  another 
patient  in  whom  I  slit  a  canaliculus  and  opened  the  dis- 
tended lachrymal  sac.  Relying  on  Dr.  Noyes'  asser- 
tion and  my  previous  observations — I  had  at  that  time 
not  read  the  contradicting  statements  of  Hager — I  sus- 
pected that  I  had  contaminated  my  supply  of  cocaine 
with  atropine  by  using  a  dropper  which  had  been  taken 
from  a  bottle  formerly  containing  duboisine,  though 
I  had  carefully  cleansed  the  dropper  and  used  it  in  six 
instances  without  noticing  mydriasis.  I  procured  fresh 
supplies  of  cocaine  in  new  glasses,  provided  with  drop- 
pers that  had  never  been  used.  This  I  used  upon  my- 
self and  four  members  of  my  family,  watching  it  a  whole 
afternoon  and  evening.  The  mydriatic  effect  of  cocaine 
of  a  two  per  cent,  as  well  as  of  a  four  per  cent,  solution 
was  positive  and  pronounced  in  all.  These  experiments 
upon  myself  and  four  other  healthy  persons  need  not  be 
described  in  extenso.     The  following  may  suffice  : 

The  instillation  of  a  two  or  four  per  cent,  solution  of 
hydrochlorate  of  cocaine  into  healthy  eyes  produces  no 
pain^  nor  any  discomfort.  During  and  after  its  action 
the  conjunctiva  does  not  change  its  aspect ;  it  is  neither 
swollen  nor  congested.  The  appearance  of  the  fundus 
oculi,  examined  ophthalmoscopically,  likewise  remains 
unchanged.  The  same  holds  with  regard  to  the  move- 
ments of  the  eyeball.  If  there  is  any  change  in  the  ten- 
sion of  the  globe,  of  which  I  could  not  positively  convince 
myself,  it  is  rather  toward  a  diminution  than  toward  an 
increase. 

The  diminution  0/ sensibility  in  the  cornea  and  con- 
junctiva varies  in  degree  in  different  individuals.  In  most 
cases  it  becomes  manifest  as  early  as  three  minutes  after 
the  first  instillation,  increases  for  ten  to  twenty  minutes, 
then  decreases,  and  is  over  in  about  half  an  hour.  When 
another  instillation  is  made,  from  ten  to  twenty  minutes 
after  the  first,  the  anaesthesia  is  more  intense,  on  super- 
ficial touching  mostly  absolute,  and  lasts  longer.  In  an 
hour  after  the  first  instillation  it  becomes  very  feeble, 
and  in  an  hour  and  a  half  it  disappears. 

The  pupil  begins  to  dilate  ten  to  twenty  minutes  after 
the  instillation,  increases  slowly,  becomes  in  some  per- 
sons as  large  as  with  atropia  in  about  thirty  to  forty-five 
minutes,  remains  stationary  for  about  thirty  minutes,  and 
then  slowly  disappears.  The  last  trace  had  disappeared 
on  the  next  day  only. 

The  range  of  accommodation  is  shortened  by  moving 
of  the  near  point  from  the  eye,  the  far  point  not  being 
appreciably  influenced.  The  shortening  of  the  range  of 
accommodation  was  limited  and  differed  somewhat  in  dif- 
ferent observers:  in  myself  it  was  equivalent  to^  (i  D); 
in  my  son,  fifteen  years  of  age,  about  the  same ;  in  Mrs. 
K ,  it  was  more.  Cocaine,  therefore,  affects  the  ac- 
commodation like  the  mydriatics.  It  reduces,  but  does 
not  paralyze  it  It  may,  therefore,  be  preferable  to  other 
mydriatics  if  we  want  to  dilate  the  pupil  for  ophthalmo- 
scopic examinations  of  the  interior  of  the  eye,  but  it  will 
probably  not  be  powerful  enough  for  determinations  of 
refraction.  It  is  a  mydriatic  which,  even  in  producing  a 
maximum  dilatation  of  the  pupil,  taJces  away  only  a  frac- 
tion of  the  power  of  accommodation.  In  Mrs.  K ^'s  and 

my  own  eye  astigmatism  manifested  itself  very  conspicu- 
ously ;  the  letters  appeared  to  slant  from  left  to  right ;  the 
left  eye  of  both  of  us  was  "cocainized."  With  her  the 
slanging  was  more  perceptible  in  near  vision,  with  me  in 
distant  vision.  The  letter  N  slanted  about  fifteen  degrees 
to  the  right,  and  was  turned  straight  by  a  +  ^rC.  ax.  110°, 
also  by  a  —  t^.  ax.  15°  or  20°,  the  same  wiui  a  +  yi^c. 
iio^O-ytrC.  20°. 

The  accommodative  power  was  restored  much  sooner 
than  the  normal  size  of  the  pupil.  In  one  and  one-fourth 
or  one  and  one-half  hour  we  could  read  again  as  easily  as 
before,  though  our  pupils  were  still  considerably  en* 
larged 


462 


THE   MEDICAL  RECORD. 


[October  25,  1884. 


Cauterisation  of  a  ^*  cocainized"  conjunctiva. — The  con- 
junctiva of  my  right  eye  was  a  little  congested,  and  at 
10.30  P.M.,  whDe  writing  this  communication,  I  dropped 
a  drop  of  a  four  per  cent,  solution  of  hydrochlorate  of 
cocaine  on  the  inner  surface  of  the  lower  lid.  Fifteen 
minutes  later  I  noticed  that  this  inner  surface  had  be- 
come pale,  paler  than  that  of  the  left  eye,  which  had  been 
the  paler  before.  I  dropped  another  drop  in,  holding  my 
head  back  so  that  the  whole  conjunctiva  was  moistened 
by  it.  Then  I  painted,  before  a  looking-glass,  a  good- 
sized  camel's-hair  brushful  of  a  two  per  cent,  solution 
(gr.  X.  ad  I  j.)  of  nitrate  of  silver  into  the  eye,  the  lower 
lid  being  everted.  I  left  the  liquid  in  place  about  twenty 
seconds,  then  it  began  slightly  to  smart,  whereas  imme- 
diately sifter  the  application  I  only  felt  the  cold,  no  pain. 
I  washed  the  nitrate  of  silver  away  with  ordinary  water,  and 
put  another  drop  of  cocaine  in.  This  relieved  the  smart 
for  five  minutes,  then  it  returned,  but  very  slightly ;  a 
serous  liquid  ran  from  my  ri^ht  nostril,  just  as  it  does 
when  a  stronger  solution  of  nitrate  of  silver  is  put  in  the 
eye  in  the  ordinary  way.  I  instilled  another  drop  of 
cocaine  and  continued  writing.  In  a  quarter  of  an  hour 
the  eye  felt  hot  and  somewhat  painful.  The  conjunctiva 
of  the  lower  lid  was  moderately,  that  of  the  adjacent 
scleral  conjunctiva  slightly,  red,  and  along  the  whole  lower 
fornix  lay  a  white  streak  of  mucus.  The  cornea  and  up- 
per scleral  and  palpebral  conjunctiva  were  white  as  if 
nothing  had  been  done.  The  pupil  was  wide,  and  the 
accommodation  somewhat  weakened,  not  so  much  as  to 
make  writing  unpleasant,  though  the  other  eye  had  been 
**  cocainized  "  in  the  afternoon  of  the  same  day. 

Experiments  on  the  Effect  of  Cocaine  on  other 
Mucous  Membranes  :  i.  Tlie  ear, — I  have  made  only 
one  experiment  in  this  locality.  It  was  successful ;  see 
later,  Case  VIII.  I  do  not  doubt  that  the  remedy  will 
find  here  a  large  field  of  application,  both  to  allay  pain 
and  to  render  the  parts  insensible  during  operations  in 
this  exceedingly  sensitive  cavity. 

2.  The  mouth. — I  can  confirm  the  former  observations 
that  the  tongue  and  the  soft  palate  become  numb.  I 
sprayed  and  brushed  my  soft  palate ;  in  ten  minutes  I 
could  pass  instruments  over  it  without  pain  or  reflex 
phenomena,  reaching,  etc  I  brushed  a  four  per  cent, 
solution  over  the  right  half  of  my  tongue  from  the  tip  to 
the  palate,  held  the  tongue  depressed  with  my  finger  and 
immovable  as  long  as  I  could  endure  it.  In  seven  min- 
utes I  repeated  the  manipulation ;  five  minutes  later  the 
right  side  of  the  tongue  and  corresponding  lip  felt  numb. 
Gentle  touching  was  not  perceived,  but  quite  well  on  the 
other  side.  Then  I  put,  with  a  fine  brush,  some  pow- 
dered sugar  on  the  insensible  parts,  successively  from  the 
tip  to  the  neighborhood  of  the  palate.  It  was  not  per- 
ceived, whereas  when  put  in  the  same  way  on  the  cor- 
responding places  of  the  other  half  of  the  tongue,  it  was 
at  once  tasted.  The  same  was  the  case  when  common  salt 
and  a  one  per  cent,  solution  of  sulphate  of  quinine  were 
placed  on  the  tongue.  In  half  an  hour  all  was  normal 
again.  Conclusion  :  Cocaine  temporarily  and  locally  de- 
stroys not  only  the  sensibility  of  the  tongue  and  pharynx^ 
but  also  the  fctculty  of  taste.  In  the  endeavor  to  suspend 
the  sense  of  taste  altogether,  I  sprayed  my  mouth  and 
palate.  The  taste  was  much  reduced,  but  not  abolished, 
evidently  because  the  remedy  in  this  experiment  had  not 
sufficiently  acted  on  all  the  portions  of  surface  from 
which  impressions  of  taste  are  received. 

3.  The  nose. — I  brushed  and  sprayed  the  nose  to  test 
the  action  of  the  new  remedy  on  the  organ  of  smell.  •The 
experiments  required  a  good  deal  of  time  and  material 
before  they  were  successful  The  lower  parts  of  the 
nose  soon  had  a  numb  feeling  and  were  insensible  to  the 
touch,  but  the  power  of  smell  was  preserved.  Bearing  in 
mind  that  olfaction  is  the  function  of  the  upper  nasal 
passages,  the  recesses  of  which  are  very  difficult  of  ac- 
cess, I  bent  my  head  down  so  as  to  make  the  vertex  its 
lowest  part,  and  introduced  the  bent  nozzle  of  a  Rich- 
ardson atomizer  in  such  a  way  that  the  spray  was  directed 


from  the  lower  to  the  middle  and  upper  nasal  passages, 
and  the  liquid  flowed  also  in  the  same  direction.  This 
manoeuvre  had  to  be  repeated  three  times  before  the 
faculty  of  smell  was  destroyed.  Perfumes  of  rose  and 
heliotrope  were  not  perceived.  Tincture  of  iodine,  con- 
centrated nitric  acid,  etc.,  produced  no  peculiar  sensation, 
whereas  on  the  other  side  they  felt  very  unpleasant  and 
produced  coughing.  Cocaine^  therefore,  temporarily  ren- 
ders the  mucous  membrane  of  the  nose  insensible  and  de- 
stroys  the  sense  of  smell.  In  less  than  half  an  hour  the 
whole  effect  of  the  remedy  had  vanished. 

4.  The  larynx  and  treuhea. — I  am  just  suffering  from 
an  attack  of  acute  bronchitis,  with  fits  of  troublesome 
coughing  in  the  morning  and  evening.  When  one  ot 
these  fits  came  in  the  evening,  I  sprayed  my  larynx  with 
cocaine  and  inhaled  it  as  well  as  I  could  by  means  of  a 
Richardson  apparatus.  The  irritation  was  at  once 
allayed,  and  soon  subsided.  I  had  no  cough,  but  half 
an  hour  later  I  expectorated,  free  from  irritation,  a  large, 
compact,  muco-purulent  sputum.  If  this  experiment 
should  be  confirmed  by  others,  and  the  effect  be  the 
same  or  similar,  cocaine  will  prove  a  great  boon  to 
patients  with  pulmonary  difficulties.  The  perfected  meth- 
ods of  introducing  medicated  substances  by  means  of 
the  ingenious  apparatuses  of  Dr.  Sass  would  relieve  the 
distress  of  coughing  and  its  prejudicial  consequences.  I 
may  add,  however,  that  the  Richardson  apparatus,  which 
seems  inadequate  for  this  purpose,  relieved  me  only  par- 
tially in  a  second,  and  not  at  all  in  a  third  attack  during 
the  night. 

5.  The  urethra. — My  urethra  is  very  sensitive  to  the 
introduction  of  instruments.  I  injected,  by  means  of  an 
Eustachian  catheter  and  a  balloon,  a  four  per  cent  solu- 
tion of  cocaine,  and  held  it  in  for  a  few  minutes.  In 
ten  minutes  the  glans  had  become  pale  and  insensible 
to  the  touch.  I  repeated  the  injection.  Seven  minutes 
later  I  introduced  a  catheter  and  other  instruments  into 
the  lu-ethra.  I  did  not  feel  them  at  all  as  far  as  3";  when 
pushed  farther  I  felt  them  very  unpleasantly  painful 
Evidently  the  cocaine  had  not  penetrated  more  deeply. 
Before  the  injection  of  cocaine  I  felt  the  instruments 
very  keenly  from  the  beginning  of  the  urethra.  To  test 
the  loss  of  sensibility  of  the  cocainized  urethra  in  anodier 
direction,  I  injected  a  one  per  cent,  solution  (gr.  v.  ad 

5j.)  of  arg.  nitr.  into  the  anterior  part  by  means  of  an 
AneFs  syringe,  introduced  as  far  as  i^".  I  had  no  sen- 
sation fi-om  it  at  all.  In  about  thirty  seconds  I  passed 
water,  which  caused  a  slight  burning,  disappearing  in 
about  a  minute.  Since  that  time  I  have  not  felt  anything 
firom  the  treatment  of  my  urethra.  This  experiment 
shows,  and  I  feel  convinced,  that  cocaine  will  prove  most 
beneficial  in  uro-genital  surgery.  It  not  only  destroys 
the  sensibility  of  the  parts,  and  therefore  admits  of  the 
easy  performance  of  many  surgical  procedures,  but  by 
being  painless  these  procedures  will  not  incite  reflex 
phenomena,  spasm,  and  the  like. 

6.  The  rectum. — For  the  sake  of  completeness  I  in- 
jected also  cocaine  into  the  rectum.  The  sensibility, 
which  was  not  great  anyhow,  was  reduced. 

In  concluding  this  communication  I  will  describe  the 

APPLICATION   OF   COCAINE   IN   DISEASES   OF   THE  EYE, 

such  as  opportunities  have  presented  themselves  to  me 
thus  far« 

Case  I. — A  young  lady,  suffering  from  convergent 
strabismus,  had,  October  15,  1884,  two  drops  of  a  two 
per  cent,  solution  of  hydrochlorate  of  cocaine,  just  ob- 
tained from  Mr.  Foucar,  dropped  into  her  eye  at  4  p.k., 
before  the  students  of  the  New  York  Ophthalmic  and 
Aural  Institute.  Three  minutes  later  the  sensibility  of 
the  cornea,  tested  with  tissue  paper  and  blunt  probes, 
was  unmistakably  diminished.  Ten  minutes  after  the 
first  application,  when  the  sensibility  of  the  cornea  and 
conjunctiva  was  greatly  reduced,  but  not  abolished,  two 
drops  more  were  instilled.  Five  minutes  later  the  anaes- 
thesia was  complete,  when  the  cornea  and  conjunctiva  were 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


463 


gentlj  touched,  but  not  when  the  squinthook  was  passed 
high  under  the  upper  lid.  Twenty  minutes  after  the  first 
instillation  the  wire  speculum  was  inserted,  the  conjunc- 
tiva grasped  with  forceps,  cut  with  scissors,  the  hook  in- 
troduced, the  tendon  divided  with  scissors,  and  the  con- 
junctival wound  closed  with  a  suture.  All  this  was  felt 
as  pain  by  the  patient,  yet  not  very  keenly.  The  sensi- 
bility was  not  abolished,  but  appeared  blunted. 

Case  II. — October  16,  1884:  I  instilled  two  drops  of 
the  above  solution  into  the  eye  of  a  lady  who  had  a  cin- 
der in  the  centre  of  the  cornea.  In  ten  minutes  the 
cornea  was  anaesthetic.  I  removed  the  cinder  by  means 
of  a  delicate  gouge,  with  very  little,  yet  not  without,  pain. 
The  removal  was  easy. 

Case  III. — October  i6th  :  The  same  solution  in- 
stilled into  the  eye  of  a  man  having  a  pterygium.  Ten 
minutes  later,  instillation  repeated.  The  cornea  and 
conjunctiva  became  insensible.  During  the  operation — 
transplantation  into  the  lower  fornix  and  covering  the  de- 
fect with  the  adjacent  conjunctiva  by  a  stitch — the  pa- 
tient manifested  about  as  much  pain  as  this  operation 
usually  causes  when  performed  without  an  anaesthetic. 

The  anaesthesia  in  these  three  cases  disappeared  al- 
most immediately  after  the  operation. 

Seeing  that  the  effect  of  the  new  anaesthetic  in  these 
three  operations  had  not  come  up  to  my  expectation,  nor 
to  what  was  claimed  for  it,  I  asked  Dr.  E.  R.  Squibb 
whether  he  could  furnish  me  a  two  per  cenL  solution  of  the 
remedy.  He  sent  me  a  four  per  cent,  solution,  remark- 
ing in  a  letter  that  the  two  per  cent,  solution  had  been 
extensively  tried  by  Dr.  C.  S.  Bull,  and  proved  only 
partially  satisfactory.  He  had  prepared  for  Dr.  Bull,  at 
his  suggestion,  a  four  per  Cent. 

Case  IV. — Of  this  solution  I  instilled,  on  October 
17th,  at  the  New  York  Ophthalmic  and  Aural  Institute, 
in  the  presence  of  the  students,  a  few  drops  into  the 
eye  of  a  cataract  patient,  aged  sixt}'-eight.  In  twenty- 
five  minutes,  during  which  time  he  had  held  his  eyes 
dosed,  there  was  complete  anaesthesia  of  the  cornea  and 
conjunctiva.  I  instilled  a  few  drops  more.  Five  min- 
utes later  I  performed  the  extraction  of  cataract  in  the 
usual  manner,  asking  the  patient  at  every  step  whether 
he  felt  any  pain.  Only  when  the  iris  was  drawn  out  and 
cut  he  said  that  it  hurt  him.  The  corneal  section  gave 
him  no  pain.  The  expulsion  of  the  lens,  which  was  done 
by  pressure  with  a  spoon  on  the  lower  segment  of  the 
cornea,  required  more  force  than  usual,  though  the  sec- 
tion was  perfectly  sufficient  and  the  capsule  not  thick- 
ened. The  eye  appeared  inelastic,  so  that  the  expulsive 
force  requisite  had  to  be  imparted  by  outward  pressure. 
The  cleansing  of  the  wound,  the  stroking  back  of  the  iris 
out  of  the  cornea,  and  the  adjustment  of  the  flap  with  a 
S[Mitula  were  not  felt  at  all.  When  the  bandage  was  ap- 
plied the  parts  were  still  insensible,  but  free  from  tdl 
irritation.  The  patient  had  felt  no  pain,  except  when 
the  iris  was  seized  and  cut ;  he  laughed  during  the  whole 
performance,  and  when  it  was  finished  he  exclaimed, 
"What I  is  that  aU?  I  have  scarcely  felt  anything.'' 
He  had  some  pain  in  the  first  thirty-six  hours,  but  no 
inflammatory  irritation. 

Case    V.— October    i8th  :  Mr.  B ,  aged  thirty. 

Cinder  in  cornea,  surrounded  by  a  white  ring,  circum- 
comeal  injection  marked  ;  since  yesterday.  Three  drops 
of  four  per  cent  solution.  Removal  twenty  minutes 
later.  Cornea  insensible.  The  dig:ging  and  scraping 
caused  no  rolling  of  the  ball,  no  winking  with  the  lids,  no 
pain.  Even  when  I  held  only  the  lower  lid  down  and 
left  the  upper  free,  the  manipulation  caused  no  closure 
of  the  lids. 

Cases  VL  and  VII.— October  i8th :  Old  trachoma. 
Insensibility  of  cornea  and  conjunctiva;  touched  with 
sulphate  of  copper.  No  pain,  no  irritation,  scarcely  any 
increased  congestion  after  the  application.  No  discom- 
fort as  when  touched  before. 

Case  VIII.— October  i8th :  Polypi  auris  after  re- 
moval of  exostosis ;  very  painful.    The   sensibility  in 


scraping  them  out  was  decidedly  diminished  in  the  super- 
ficial layers,  not  in  the  depth  after  two  instillations  of 
cocaine. 

Case  IX. — October  19th  :  Mrs.  N ,  aged  fifty-six. 

Conjunctivitis  of  both  eyes,  tumor  sacci  lacrymalis  of  the 
left  Four  per  cent  cocaine,  six  drops  in  conjunctival 
sac  and  on  lachrymal  points ;  ten  minutes  later  cornea 
and  conjunctiva  anaesthetic,  pupil  slightly  dilated.  Ten- 
sion of  globe  the  same.  The  introduction  of  Weber's 
knife  through  one-half  of  the  canaliculus  is  not  felt,  the 
pushing  forward  into  the  sac  and  slitting  the  inner  wall 
of  the  sac,  and  passing  a  thick  probe  into  the  nose,  are 
felt  painfiil,  but  it  seems  less  than  usual. 

October  19, 1884. 

THE  NEW  LOCAL  ANESTHETIC. 
By   D.   B.    ST.   JOHN    ROOSA,  M.D.,  LL.D., 

PROFBSSOK  OF  DISEASES  OP  BYB  AKD    BAK,   NEW    YORK    POST-GRADUATE  SCHOOL. 

I  HAVE  been  using  the  chloride  of  cocoaine,  as  a  local 
anaesthetic,  for  the  last  ten  days,  in  operations  upon  the 
eye,  and  in  one  case  of  neuralgia  of  the  tympanum.  The 
preparation  employed  was  a  two  per  cent  solution  made 
by  Mr.  Foucar.  In  the  first  case  the  internal  rectus 
muscle  was  divided.  The  subject  was  a  young  woman. 
She  experienced  no  pain  until  the  muscle  was  taken  up 
by  the  hook,  and  then  she  cried  out  rather  lustily,  but 
she  did  not  become  at  all  unmanageable.  In  the  second 
case  I  divided  both  external  recti  and  brought  forward 
the  internal  rectus.  The  cocoaine  was  used  in  this  case 
every  five  minutes  for  fifteen  or  twenty  minutes  before 
the  operation,  and  some  three  or  four  times  during  its 
performance.  The  patient  was  a  young  and  healthy 
man,  a  clergyman  by  profession.  He  said  the  pain  was 
inconsiderable,  and  I  had  no  trouble  during  the  opera- 
tion from  his  movements.  Indeed,  he  seemed  to  suffer 
very  little. 

On  the  2oth  I  extracted  a  cataractous  lens,  in  its 
capsule  without  an  iridectomy^  while  the  eye  was  under 
the  influence  of  the  new  local  anaesthetic  None  of  the 
stages  of  the  operation  caused  anything  but  trifling  pain. 
The  eye  remained  steady  and  tractable  to  the  end  of 
the  manipulations,  and  no  accident  occurred.  The  oper- 
ation was  witnessed  by  Dr.  Vosburg,  of  this  city.  Dr.  G. 
J.  Bull,  Dr.  Ring,  and  Dr.  Tewksbury.  October  21st  I 
divided  the  internal  rectus,  and  employed  the  cocaine 
in  the  usual  way,  that  is,  two  drops  every  five  minutes 
for  fifteen  or  twenty  minutes  before  tlie  operation,  and 
once  during  it.  The  patient  experienced  considerable 
pain,  and  said  she  would  take  ether  the  next  time. 

As  intimated  above,  I  have  used  the  drug  locally — 
upon  the  membrana  tympani — in  one  case  of  that  rare 
disease,  tympanic  neuralgia.  The  patient  said  the  pain 
was  relieved  in  ten  minutes  after  two  instillations.  I 
have  used  it  for  the  operation  of  slitting  up  the  canaliculi 
and  probing  the  nasal  duct,  but  as  yet  without  any  alle- 
viation of  the  pain  usually  caused.  Except  in  one  case, 
dilatation  of  the  pupil  has  always  been  produced  in  my 
cases,  but  no  other  unpleasant  symptom. 

Since  writing  the  above  I  have  performed  two  opera- 
tions upon  the  eye,  while  under  the  influence  of  the  nm- 
riate  of  cocoaine,  with  the  most  satisfactory  results.  In 
these  cases  a  two  per  cent  solution  was  used,  but  it  was 
instilled  three  to  four  drops  at  a  time,  every  three  min- 
utes for  fifteen  minutes.  In  one  of  these  last  cases  I 
divided  the  internal  rectus  of  a  boy  of  twelve  years.  He 
declared  that  the  operation  did  not  cause  him  greater 
pain  than  was  produced  by  pinching  the  skin  of  his  hand. 
The  last  case  was  one  of  division  of  both  the  external 
recti  muscles  in  a  man  of  about  thirty-four  years  of  age. 
He  declared  that  the  pain  was  of  no  consequence  what- 
ever, and  talked  freely  with  me  while  I  was  engaged 
upon  his  eye. 

Over  $7,000  have  thus  far  been  collected  by  The 
Medical  Record  for  the  Sims  Memorial  Fund. 


464 


THE  MEDICAL  RECORD. 


[October  25,  1884. 


The  Medical  Record-. 


A  Weekly  Journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co..   Nos.  56  and  58  Lafayette  Place. 

New  York,  October  25,  1884. 

A   PLEA   FOR  THE  COUNTRY   DOCTOR 

The  best  elements  of  our  character  are  always  brought 
out  by  opposition.  Environment  determines  many 
points  of  excellence  which  cannot  be  developed  by  any 
other  means.  It  applies  to  the  doctor  as  well  as  to  others 
of  the  genus  homo.  The  rural  practitioner  especially  is 
full  of  controlling  surroundings.  If  he  gets  the  better  of 
them  he  is  so  much  more  of  a  man.  Every  one  who 
knows  him  sympathizes  with  him  in  his  every-day  fight, 
and  credits  him  with  his  well-earned  successes.  The 
letter  in  another  column  refreshes  a  picture  which  is  full 
of  cold  shadows  and  rugged  outline.  The  central  figure 
is  the  country  doctor  and  his  horse  struggling  through 
the  deep  trough  of  a  muddy  road,  with  a  background  of 
bleak  hill,  and  trees  bare-poled  to  meet  the  whistling 
wind.  No  fancy  sketch,  as  he  can  tell  us,  but  full  of 
reality  to  thousands  of  fellow-workers.  Hardly  appreci- 
ated, however,  by  the  metropolitan  brother  in  his  cush- 
ioned coup^,  trundling  over  Macadamized  avenues  to 
sick  millionaires.^ 

But  after  all,  taking  ordinary  chances,  we  would  be 
inclined  to  side  with  the  country  doctor  in  any  emergency 
occurring  in  general  practice.  A  man  who  can  extricate 
his  horse  from  a  snow-drift  on  a  dark  road  may  not  be 
lacking  in  resources  to  dislodge  an  impacted  foetal  head, 
cut  the  bridle  of  a  strangulated  hernia,  or  make  a  new 
path  for  a  bean  in  the  trachea.  That  he  is  accustomed 
to  shoulder  responsibility  hardly  tells  against  him  in  his 
general  results.  His  resources  widen  with  his  oppor- 
tunities, and  when  he  makes  his  own  path  up  the  moun- 
tain he  can  the  better  appreciate  the  broadened  view 
which  he  gains.  If  he  has  to  swim  without  corks  he  can 
float  with  the  more  confidence  in  the  deeper  waters. 

There  is  more  of  an  education  for  a  doctor  than  is 
comprised  in  the  dosage  of  pills  or  the  action  of  powders, 
and  the  country  doctor  gets  it  very  often  in  his  daily 
contact  with  man  and  nature.  Insensibly  he  strikes  a  bal- 
ance between  the  capabilities  of  the  one  and  the  power  of 
the  other.  Matter-of-fact,  it  is  true,  but  practical  always. 
He  may  not  have  time  to  look  after  the  countless  micro- 
cocci that  fill  the  scientific  air,  but  he  takes  care  that 
they  do  not  obscure  the  view  of  the  end  of  his  road. 
His  destination  must  be  to  cure  his  patient.  If  he  fails, 
his  good  friends  in  and  out  of  the  profession  will  know 
it.  Consequently  he  must  be  the  general  practitioner 
par  excellence^  as  ready  to  brighten  the  headlights  as  to 
handle  the  tiller. 


The  type  of  the  general  practitioner  is  the  self-reliant 
man  on  the  dark  countty  highway,  whose  every  instinct 
teaches  him  to  keep  the  road,  whether  it  be  going  to  a 
patient  or  at  a  patient. 

It  is  truthfully  said  that  he  cannot  call  for  help  al- 
ways ;  therefore  he  helps  himself.     It  is  not  so  much  the 
instrument  as  the  brains  behind  it.     A  man  of  sound 
practical  sense  may  treat  a  fractured  thigh  sometimes 
better  in  the  backwoods  with  a  forked  stick  and  piece 
of  blanket  than  can  another  with  an  improved  "  Buck's 
extension "  in   a  metropolitan  hospital.     It  is  the  dif- 
ference in  the  man  wherever  he  is.     The  doctor  in  the 
country  has  the  best  of  it  because  he  has  more  chance 
to  develop  himself,  and  when  he  does  it  he  need  not 
envy  the  city  man  who  steadies  his  professional  stand- 
ing by  fastening  intellectual  guy-ropes  to  the  bell-call  of 
every  neighboring  specialist.     These  dependents  are  not 
the  backbone  of  the   profession.     They  can  only  wrig- 
gle   their  way  to  patronage  while   they  are   riding  the 
ground-swell  of  the  bigger  fish.     They  could  not  live  so 
well  in  the  country.     We  are  speaking  now  of  the  ex- 
tremes of  dependents  and  independents  in  their  respec- 
tive types  of  general  practitioners  in  and  out  of  the  cities. 
If  they  were  to  change  places  specialism  in   the  cities 
would  suffer  and  general  practice  in  the  country  would 
hardly  improve.     So  much  for  the  claims  of  the  progres- 
sive, wide-awake,  and  self-reli^int  country  practitioner. 

Our  correspondent  allows  the  current  of  his  enthusi- 
astic advocacy  of  his  class  to  take  him  slightly  beyond  his 
depth  when  he  implies  that  living  in  the  city  is  not  more 
expensive  than  in  the  country,  and  that  the  metropolitan 
has  everything  he  may  wish  for.  Stop  at  the  hundreds 
of  signs  on  the  avenue  highways  and  side-street  byways 
and  ask' how  it  is.  To  display  such  a  light  on  a  city  hill  is 
very  different  from  merely  removing  the  country  bushel 
The  yearly  rental  of  a  house  on  an  avenue  would  buy  a 
country  cottage,  while  the  first  cost  of  a  coup^  would 
cover  the  contract  for  a  bam,  with  possibly  a  good  horse 
thrown  in.  Where  much  is  spent  much  must  be  earned. 
The  ambitious  metropolitan  works  as  hard  as  the  rustic, 
with  hardly  as  good  a  show  on  the  grand  track.  They, 
in  fact,  both  need  rest.  Both  should  take  it.  It  would 
do  the  rural  gentleman  as  much  good  to  visit  the  city  in 
the  winter,  and  exchange  his  muddy  paths  for  dry  pave- 
ments and  his  snow-drifts  for  closed  cars,  his  patient's 
bedside  for  hospital  ward  and  his  saddle  for  the  orches- 
tral chair,  as  it  would  in  summer  for  the  city  man  to 
climb  the  hills,  to  sail  the  lakes,  cast  the  fly,  or  hunt  the 
deer.  It  is  the  change  which  gives  the  rest — the  rustic 
may  study  interiors,  the  metropolitan  develop  exteriors 
Both  would  be  benefited  thereby  and  escape  the  eflfccts 
of  that  continuous  drudgery  which  too  often  breaks  the 
backbone  of  a  noble  aspiration. 


THE  PATHOLOGY  OF  LAWN-TENNIS. 
For  two  or  three  years  English  medical  journals  have 
had,  now  and  then,  letters  about'** lawn-tennis  arm," 
"lawn-tennis  elbow,'*  and  "  lawn-tennis  leg." /^.  Any  phy- 
sician ¥^0  meets  many  lawn-tennis  players  is'quite  sure 
to  find  some  who  complain  of  J  a  trouble  with  the  wiist, 
or  forearm,  or  elbow.  These  troubles  are  rather  more 
apt  to  occur  among  the  beginners,  since  they  are  due  to 
the  very  sudden  and  often  unnecessarily  violent  musco- 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


465 


lar  contractions  which  the  too  ambitious  player  makes. 

Xhey  are  also  rather  more  frequent  among  elderly 
persons.  Hence  we  hear  more  of  them  in  England, 
where  persons  of  every  age  play  tennis. 

The  "lawn- tennis  arm,'*  so*called,  appears  to  be  gen- 
erally due  to  a  rupture  of  the  pronator  radii  teres.  This 
is  a  slender  muscle,  and  the  sudden  call  upon  it  in  using 
the  racket  sometimes  does  it  an  injury.  After  long 
practice,  however,  the  pronating  power  of  this  muscle  is 
very  much  increased  and  the  danger  of  injury  is  less. 
When  an  accident  to  it  occurs  the  victim  feels  pain  on 
flexing  ox  pronating  the  forearm  ;  there  is  tenderness, 
and  perhaps  swelling  and  discoloration  along  its  course. 
Doubtless  the  muscle  in  question  is  not  ruptured  en- 
tirely, but  only  as  to  some  of  its  fibres,  while  coinci- 
dently  there  is  a  good  deal  of  stretching  and  perhaps 
tearing  of  the  fibrous  and  ligamentous  tissues  on  the  in- 
ner side  of  the  elbow,  near  where  the  muscle  arises. 

Another  form  of  **Jawn-tennis  arm/*  appears  to  be  due 
to  an  injury  to  the  musculo-spiral  nerve  or  its  posterior 
interosseous  branch.  This  nerve  winds  around  the  outer 
side  of  the  humerus  beneath  the  triceps  muscle  and  de- 
scends between  the  long  supinator  of  the  wrist  and  the 
brachialis  anticus.  In  other  words,  it  passes  close  to, 
and  supplies,  two  muscles  that  are  brought  into  powerful 
action  in  back-handed  strokes.  When  these  strokes  are 
made  too  suddenly  and  violently  by  unseasoned  muscles 
the  contractions  appear  either  to  injure  the  extensors 
and  supinators  of  the  arm,  tearing  some  of  their  fibres, 
or  perhaps  the  nerve  itself  is  injured  by  the  violent 
squeezing  which  it  gets.  At  any  rate  there  is  a  quietus 
pat  upon  back-hand  strokes  for  a  time. 

We  have  seen  tennis  players  who  suffered  from  weak- 
ness of  the  wrist  The  violent  Jflexing  of  the  fingers  and 
wrist  has  in  these  cases  stretched  or  torn  some  fibres  of 
the  anterior  annular  ligament,  which  holds  the  flexor 
tendons  down.  Sometimes  a  slight  teno-synovitis  seems 
to  be  set  up.  A  firm  rubber  band  is  a  great  help  in 
these  cases. 

Tennis  players  may  and  do  suffer  fi-om  ordinary  sprains 
of  the  elbow  or  shoulder.  In  these  there  is  nothing  dis- 
tinctive or  peculiar. 

Besides  "  tennis  arms,''  we  have  "  tennis  legs."  For 
example :  A  player  while  serving  a  ball  with  a  powerful 
cut-down  stroke  suddenly  felt  a  sharp  pain  in  the  calf  of 
his  leg  and  the  leg  immediately  became  powerless.  A 
few  days  later  large  black-and-blue  spots  appeared  on 
the  calf.  This  patient  had  a  ''  tennis  leg."  The  trouble 
was  caused  by  a  rupture  of  some  of  the  calf  muscles. 
The  English  writers  assume  the  affected  muscle  to  be 
the  small  and  rudimentary  plantaris  longus.  Certainly 
there  is  more  involved  than  this  in  many  cases. 

The  treatment  for  all  the  foregoing  pathological  prod- 
ucts of  athletic  activity  is,  in  the  main,  rest,  massage, 
and  elastic  compression.  Sometimes  the  use  of  elastic 
bandages,  such  as  Martin's,  enables  one  to  use  the  in- 
jured arm  very  soon.  At  other  times  the  trouble  is 
more  obstinate,  and  the  arm  has  to  be  given  almost  com- 
plete rest  for  a  long  time.  When  the  nerve  is  injured, 
electricity  is  very  usefiil.  A  bad  tennis  leg  may  require 
a  starch  bandage  and  a  high-heeled  shoe  for  a  time. 

In  conclusion,  we  would  say  that  tennis  players  need 
not  feel  alarmed  by  this  description  of  the  possible  acci- 


dents in  the  game.  The  proportion  of  tennis  arms  and 
tennis  legs  is  extremely  small.  It  may  even  be  ques- 
tioned if  young  and  perfectly  healthy  persons  can  rup- 
ture their  muscles  in  using  a  tennis  racket.  Certainly 
such  a  thing  is  of  rare  occurrence.  But  non-athletes 
who  take  up  tennis  after  thirty  should  be  a  little  carefuL 


THE  NEW  YORK  STATE  MEDICAL  SOCIETY. 

Circulars  have  been  issued  by  Dr.  B.  F.  Sherman, 
President  of  the  New  York  State  Medical  Society,  re- 
questing that  the  titles  of  papers  to  be  read  at  the  next 
meeting  be  sent  in  by  the  first  of  December.  It  is  de- 
sired that  the  full  list  should  be  published  at  that  time,  so 
that  the  discussions  may  be  full  and  exhaustive. 

The  object  of  the  President  is  praiseworthy,  but  he  will 
not  attain  it  by  the  method  alone  which  he  proposes.  If 
the  titles  of  any  large  proportion  of  the  papers  could  be 
obtained  so  early  as  December  ist,  which  is  doubtful, 
members  would  be  very  likely  to  forget  them  before  Feb- 
ruary. Apart  from  this,  however,  every  one  knows  who 
has  attended  State  meetings  that  more  radical  changes 
must  be  made  in  order  to  secure  valuable  discussions. 
At  present,  there  are  generally  too  many  papers  for  the 
time  of  the  Society.  The  discussions  have  to  be  cut 
short,  instead  of  being  encouraged.  Nor  is  there  any 
systematic  attempt  to  get  good  dbcussions.  Experience 
with  medical  men  and  medical  meetings  shows  that  it  is 
only  rarely  that  good  discussions  are  secured  without 
previously  canvassing  members  and  seeing  that  those 
who  can  speak  instructively  are  present  and  prepared. 

It  is  possible  that  at  the  next  naeeting,  with  the  Code 
question  no  longer  to  vex  us,  there  may  be  time  for  the 
full  presentation  and  consideration  of  papers.  If  not, 
however,  some  radical  change  must  be  made.  Sections 
must  be  established — a  measure  of  questionable  wisdom 
— or  the  meetings  prolonged,  or  the  number  of  papers  ac- 
cepted must  be  more  carefully  limited. 

The  practice  of  urging  readers  of  papers  to  have 
printed  slips  of  an  abstract  for  distribution  to  the  mem« 
bers  sometimes  increases  the  interest  in  papers  that  are 
long  or  very  technical,  and  the  question  of  its  adoption 
should  be  borne  in  mind  by  the  Business  Committee. 


SUITS  ARISING  OVER  INJURIES;, 

The  suits  arising  over  injuries  incurred  in  accidents,  espe- 
cially those  connected  with  railroad  collisions,  often  bring 
up  the  question  of  the  skill  of  the  attending  physician  or 
surgeon,  and  the  railroad  companies  lay  great  stress  wher- 
ever possible  upon  the  alleged  incompetence  or  negli- 
gence of  the  professional  attendant.  If  this  defence  were 
allowed  to  the  extent  it  is  sometimes  pushed,  the  poor 
victim  of  a  collision  would  be  obliged  to  warrant  that  the 
utmost  skill  had  been  exercised  by  the  surgeon,  or  else  he 
could  not  recover  any  damages.  This  is  not  the  rule 
adopted  by  the  courts,  which  generally  hold  that  all  that 
can  be  legally  exacted  of  the  sufferer  is  ordinary  care  and 
skill  in  the  choice  of  an  attendant.  A  recent  case  in 
Pennsylvania  states  this  principle,  where  the  injury  was  a 
broken  arm,  and  the  ruling  of  the  judge  was  as  follows  : 
'*  There  is  evidence  tending  to  show  that,  had  this  broken 
arm  received  ordinar}-  care  and  ordinary  professional  skill. 


466 


THE  MEDICAL  RECORD. 


[October  25, 1884. 


the  parts  would  have  united  with  little  or  no  permanent 
injury,  and  on  this  hypothesis  alone  appellant  insists 
that  the  matter  of  this  false  joint  should  have  been,  at 
least  hypothetically,  excluded  from  the  jury.  We  under- 
stand the  law  on  the  subject  to  be  that  plaintiff  cannot 
hold  defendant  answerable  for  any  injury  caused,  even  in 
party  by  the  fault  of  plaintiff  in  failing  to  use  ordinary 
care  or  ordinary  judgment,  or  for  any  injury  not  resulting 
from  the  fault  of  defendant,  but  caused  by  some  new  in- 
tervening cause  not  incident  to  the  injury  caused  by 
defendant's  wrong.  Thus,  in  this  case,  if  it  be  conceded 
that  the  false  joint,  under  proper  care  and  skill,  would 
not  have  resulted  from  the  breaking  of  the  arm  alone, 
but  was  brought  about  by  the  subsequent  separation  of 
the  parts-  after  they  had  been  properly  set,  and  before 
nature  had  formed  a  firm  union,  then  if  this  subsequent 
separation  of  the  parts  had  been  caused  by  an  assault 
and  battery  by  a  stranger,  or  some  foreign  cause  with 
which  appellant  had  no  connection,  and  which  was  not 
in  its  nature  incident  to  a  broken  arm,  plainly  appellant 
ought  not  to  be  held  to  answer  for  the  false  joint ;  but  if 
appellee  exercised  ordinary  care  to  keep  the  parts  to- 
gether, and  used  ordinary  care  in  the  selection  of  sur- 
geons and  doctors,  and  nurses,  if  needed,  and  employed 
those  of  ordinary  skill  and  care  in  their  profession,  and 
still  by  some  unskilful  or  negligent  act  of  such  nurses,  or 
doctors,  or  surgeons,  the  parts  became  separated  and 
the  false  joint  was  the  result,  appellant,  if  responsible  for 
the  breaking  of  the  arm,  ought  to  answer  for  the  injury 
in  the  false  joint.  The  appellee,  when  injured,  was 
bound  by  law  to  use  ordinary  care  to  render  the  injury 
no  greater  than  necessary.  It  was,  therefore,  his  duty 
to  employ  such  surgeons  and  nurses  as  ordinary  pru- 
dence in  his  situation  required,  and  to  use  ordinary  judg- 
ment and  care  in  doing  so,  and  to  select  only  such  as 
were  of  at  least  ordinary  skill  and  care  in  their  profes- 
sion. But  the  law  does  not  make  him  an  insurer  in  such 
case  that  such  surgeons,  or  doctors,  or  nurses,  will  be 
guilty  of  no  negligence,  error  in  judgment,  or  want  of 
care.  The  liability  to  mistakes  in  curing  is  incident  to 
a  broken  arm,  and  where  such  mistakes  occur  (the  in- 
jured party  using  ordinary  care),  the  injury  resulting 
from  such  mistakes  is  properly  regarded  as  part  of  the 
immediate  and  direct^  damages  resulting  from  the  break- 
ing of  the  arm." 

PALLIATIVE    MEASURES    IN    RUPTURED    EXTRA- 
UTERINE   PREGNANCY. 

Another  woman  has  passed  from  health  to  the  grave  in 
a  few  hours  ;  another  home  has  been  made  desolate ;  and 
another  victim  to  delay  and  palliative  hypodermatics  of 
morphia  and  brandy-and-water  in  drachm  doses  has  been 
added  to  the  list,  already  too  long,  of  cases  that  have 
been  lost  for  want  of  surgical  treatment. 

A  case  has  been  recently  reported,  in  a  Western  medi- 
cal journal,  in  which  the  symptoms  of  rupture  of  an  extra- 
uterine foetal  sac  were  complete,  and  the  diagnosis  of 
extra-uterine  pregnancy  was  concurred  in  by  three  prac- 
titioners, and  the  following  treatment  adopted  :  *'  Sulphate 
of  morphia  in  one-sixth-grain  doses,  hypodermatically,  to 
control  the  pain,  and  brandy,  both  by  the  mouth  and 
under  the  skin,  as  a  stimulant.  A  sinapism  over  the 
stomach  and  bowels  assisted  in  giving  some  measure  of 


relief."  The  patient  died  in  sixteen  hours  and  a  halt 
Nothing  is  said  of  an  attempt  to  control  the  hemorrhage, 
which  every  one  must  have  known  was  draining  away  the 
woman's  life.  Nothing  is  said  of  a  desire  to  open  the 
abdominal  cavity  to  stop  the  hemorrhage  and  remove  the 
foreign  body.  Is  the  recorded  experience  and  the  teach- 
ing  of  the  surgical  leaders  of  the  day  to  go  for  nothing? 
Are  there  any  who  think  that  a  patient  in  this  situation 
dies  of  aught  else  save  hemorrhage,  and  controllable 
hemorriiage?  If  the  hemorrhage  be  not  controllable, 
why  do  the  patients  live  for  sixteen  and  twenty  or  thirty 
hours  after  the  rupture  ?  Are  there  those  in  the  profes- 
sion who  do  not  know  that  the  mere  exposure  of  the  ab- 
dominal cavity  to  the  air  will  often  check  a  hemonhag^ 
which  would  otherwise  prove  fatal  in  the  closed  cavity? 
Surely  in  these  days  of  great  and  brilliant  triumphs  in 
abdominal  surgery,  when  patients  recover  after  intestinal 
wounds  and  resections,  when  the  most  desperate  "forlorn 
hopes  "  recover,  one  should  not  hesitate  to  open  the  ab- 
domen in  a  case  of  this  kind,  when  two  or  three  ligatures 
and  some  clean  water  are  all  that  are  required. 

There  is  no  palliative  measure  for  a  ruptured  extra- 
uterine cyst ;  there  is  no  expectant  treatment ;  and  there 
is  no  other  way  known  to  medicine  by  which  a  woman 
in  this  condition  can  be  reasonably  expected  to  survive 
save  by  the  prompt  use  of  the  knife — and  there  is  no 
reason  for  thinking  that  she  would  die  if  this  be  resorted 
to  in  time.  And  until  she  is  practically  dead  it  is  never 
too  late  to  try  and  save  her. 


MR.  VANDERBILTS  GIFT. 

The  College  of  Physicians  and  Surgeons  deserves  warm 
congratulations  upon  the  magnificent  gift  of  half  a  mil- 
lion dollars  which  has  been  so  generously  made  to  it  by 
Mr.  William  H.  Vanderbilt  Such  a  donation  is  unpre- 
cedented in  the  history  of  American  medical  colleges. 
It  places  the  fortunate  institution  among  the  few  endowed 
medical  colleges  in  this  country,  and  will  enable  it  to 
carry  out  the  efforts  at  a  higher  education  which  it  has 
already  shown  itself  desirous  of  making. 

The  medical  colleges  in  this  country  which,  in  1881,  had 
productive  funds  were  the  following :  Yale  Medical  Col- 
lege, $29,102;  Harvard  Medical  School,  $280,391;  Med- 
ical Department  of  University  of  Pennsylvania,  $50,000, 
and  Johns  Hopkins  Medical  School  (not  yet  open).  Be- 
sides these,  the  McHarry  Medical  College,  the  Howard 
University  Medical  School,  and  the  Kansas  City  Medical 
College  have  small  endowments ;  while  several  others, 
such  as  Dartmouth  and  Bellevue,  have  had  large  sums 
of  money  presented  for  specific  purposes.  A  number  of 
Western  medical  colleges  also  give  tuition  free  and  are 
supported  entirely  by  the  State. 

The  Faculty  of  the  College  of  Physicians  and  Surgeons 
of  New  York  already  has  property  valued  at  nearly 
$200,000.  With  its  recent  gift,  therefore,  it  becomes  the 
richest  institution  of  the  kind  in  America.  It  is  an- 
nounced that  the  money  will  be  used,  in  part  at  least, 
for  the  construction  of  a  new  building,  which  will  be 
erected  in  the  northwestern  part  of  the  city,  in  the  vicin- 
ity of  Roosevelt  Hospital.  Such  a  move,  if  made,  will 
be  a  bold  one,  since  tradition  has  heretofore  located 
medical  instruction  upon  the  east  side  of  the  city.    By 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


467 


the  enlargement  of  Roosevelt,  the  construction  of  a  ma- 
ternity hospital,  and  the  development  of  dispensaries,  the 
part  of  the  city  referred  to  could  probably,  in  time,  be 
made  another  medical  centre. 

Roosevelt  Hospital,  however,  will  meanwhile  have  to 
undergo  some  radical  and  needed  changes  in  the  ar- 
rangement of  its  visiting  services.  For  although  it  is 
admirably  managed  in  a  way,  nevertheless  in  usefulness 
to  medical  and  surgical  science,  and  for  the  purposes  of 
practical  instruction,  it  has  been  falling  behind. 


^ews  of  tUi^  WCei^U. 


Muriate  of  Cocaine  in  the  Operation  for  Cata- 
ract.— ^The  operation  for  double  senile  cataract  was 
successfully  performed  this  week  at  Mount  Sinai  Hos- 
pital, muriate  of  cocaine  being  used,  and  no  general  an- 
aesthetic.     The  patient  experienced  no  pain. 

A  Journalistic  Change.— It  is  announced  that  TA€ 
Therapeutic  Gazette  will  be  moved  to  Philadelphia,  where 
it  will  be  edited  by  Professor  H.  C.  Wood  and  Professor 
Robert  Meade  Smith.  The  Gazette  will  still  be  pub- 
lished by  Mr.  George  S.  Davis,  of  Detroit,  whose  liberal- 
ity and  energy  have  already  done  so  much  for  it  We 
welcome  Professor  Wood  back  to  the  field  of  journalism. 
His  editorship  insures  to  the  profession  a  journal  in  the 
interests  of  scientific  pharmacology  as. well  as  of  practical 
therapeutics. 

The  Hospital  Saturday  and  Sunday  Assoclation 
held  its  first  meeting  for  the  fall  during  the  past  week. 
A  report  was  made  by  the  general  agent  of  the  Society, 
Mr.  F.  J.  Cook,  in  which  it  was  stated  that  the  work  was 
well  advanced,  and  that  there  was  an  excellent  prospect. 
There  would,  in  all  probability,  be  a  larger  collection 
from  the  churches  than  heretofore.  The  members  of 
additional  trade  auxiliaries  had  been  brought  into  the 
work,  having  been  organized  during  the  summer. 

The  So-called  Gonococcus  Normally  Present  in 
the  Healthy  Urethra.— Dr.  E.  C.  Wendt,  of  New 
York,  writes  that  with  the  aid  of  a  suitable  instrument 
he  has  examined  the  scrapings  from  different  portions  of 
the  healthy  male  urethra.  In  every  instance  these  scrap- 
ings were  found  to  contain,  in  greater  or  less  abundance, 
micrococci  morphologically  identical  with  Neisser's  so- 
called  gonococcL  The  inference  is  obvious.  He  intends 
at  a  later  d^e  to  publish  the  detailed  results  of  a  large 
number  of  observations,  which,  in  conjunction  with  Dr. 
C.  W.  Allen,  of  New  York,  he  has  already  made,  and  is 
still  engaged  in  making. 

Washington  Obstetrical  and  Gynecological  So- 
ciety.— At  a  regular  meeting  of  the  Washington  Ob- 
stetrical and  Gynecological  Society,  held  October  17, 1884, 
the  following  officers  were  elected  for  the  ensuing  year: 
^r^x/Vfe«/— Samuel  C.  Busey,  M.D. ;  Vice-Presidents^-- 
W.  W.  Johnston,  M.D.,  and  J.  Taber  Johnson,  M.D. ; 
Recording  Secretary — C.  H.  A.  Klineschmidt,  M.D. ; 
Corresponding  Secretary  —  Samuel  S.  Adams,  M.D. ; 
7r^<M»r^r— George  Byrd  Harrison,  M.D. 

Dr.  Domingo  Orvananos,  the  Secretary  of  the  Board 
of  Health  of  the  City  of  Mexico,  has  been  in  this  city 
studying  our  methods  of  sanitary  administration. 


Death  of  Professor  F.  A.  Ross. — Dr.  F.  A.  Ross, 
of  Mobile,  Ala.,  died  October  17th,  of  apoplexy.  He 
was  bom  in  1821,  and  was  graduated  at  several  institu- 
tions of  learning,  including  the  University  of  Virginia  and 
the  Pennsylvania  Medical  College.  He  served  as  Surgeon 
of  the  Palmetto  Regiment  during  the  Mexican  war,  and 
during  the  war  of  the  rebellion  was  the  Medical  Director 
of  the  Department  of  the  Gulf,  under  the  Confederate 
Government.  He  was  at  one  time  President  of  the  Mobile 
Medical  Society  and  of  the  Alabama  Medical  Society, 
and  Professor  of  Therapeutics  in  the  Mobile  Medical 
College. 

"Dead  Teeth  in  the  Jaws." — Dr.  C.  E.  Nelson 
writes:  "In  my  communication  to  you  on  this  subject 
(October  18,  1884),  on  page  444  of  The  Record,  I  no- 
tice two  important  typographical  errors,  which  I  should 
like  corrected.  In  the  second  column,  line  25  from  bot- 
tom, for  nominally  read  normally.  In  line  8  from  bot- 
tom, for  than  read  then'' 

The  New  York  State  Medical  Association. — 
The  Fellows  and  delegates  of  the  New  York  State  Med- 
ical Association  assemble  in  this  city  on  the  third  Tues- 
day in  November  next  (the  i8th).  The  Association  is 
at  present  composed  of  168  founders,  representing  40 
out  of  the  61  counties  of  the  State.  Half  of  the  found- 
ers come  from  six  counties,  New  York  having  33,  Rens- 
selaer County  coming  next  with  14,  and  King's  County 
last  with  7.  Sixteen  counties  have  one  representative.  It 
has  been  voted  to  call  the  members  Fellows.  A  com- 
mittee, consisting  of  Drs.  A.  Flint,  Jr.,  Van  de  Warker, 
and  Gouley,  has  been  appointed  for  the  purpose  of  se- 
curing the  co-operation  of  a  medical  journal  in  harmony 
with  the  objects  of  the  Association.  It  has  been  voted 
that  members  who  are  to  read  papers  shall  have  a  synop- 
sis printed  for  distribution.  The  main  object  of  the  As- 
sociation is  to  secure  to  the  profession  in  New  York  State 
representation  in  the  American  Medical  Association. 
The  question  will,  therefore,  doubtless  be  raised  whether 
those  counties  in  which  medical  societies  have  not 
changed  their  old  code  and  which  are  still  entitled  to 
representation  can  send  a  double  set 

The  Report  of  the  French  Cholera  Commis- 
sion AT  Marseilles. — This  commission,  consisting  of 
seven  members,  of  whom  only  five  acted,  viz.,  MM. 
Sicard,  Taxier,  Loucel,  Livon,  and  Chareyre,  offers  the 
following  conclusions:  "i.  The  cholera  is  transmissible 
to  the  rabbit,  as  demonstrated  by  injection  into  the 
veins  of  the  blood  of  a  cholera-patient  at  the  algid 
period.  The  rabbit  died  in  twenty-four  hours,  with 
lesions  entirely  like  those  of  cholera.  2.  By  cultivation, 
this  blood  afrer  a  few  hours  loses  its  infectious  properties. 
3.  Injections  of  choleraic  blood  in  the  period  of  reaction, 
or  a  very  advanced  algid  period,  produce  no  effect  4. 
The  perspiration  of  a  cholera-patient,  injected  into  the 
veins,  does  not  transmit  cholera.  5.  The  stomachic  or 
intestinal  dejections,  or  the  gastro-intestinal  contents 
(this  last  full  of  comma-bacilli),  may,  after  filtration,  be 
injected  with  impunity  into  the  cellular  tissue  of  the 
peritoneum,  the  windpipe,  the  intestines,  the  rectum,  and 
even  into  the  blood.  6.  Comma-bacilli  taken  from  the 
intestines  of  a  cholera-patient  may  be  introduced  into 
the  intestines  of  a  rabbit,  and  multiply  there  for  more 


468 


THE   MEDICAL  RECORD.^ 


[October  25,  1884. 


than  eleven  days,  without  producing  any  choleraic  symp- 
toms, and  without  necropsy  revealing  the  anatomo- patho- 
logical lesions  characteristic  of  cholera.  7.  There  is 
thus  every  proof  of  the  non-specificity  of  the  comma- 
bacillus.  We  experimented  on  bacilli  taken  from  the 
intestine,  and  with  dejections  kept  from  two  to  twelve 
days,  the  results  being  always  negative.  Everything  also 
proves  that  this  bacillus  does  not  produce  in  the  intes- 
tine toxical  ptomaines  which  would  be  the  cause  of 
poisoning — namely,  the  lesion  of  the  blood.  The  infer- 
ence from  more  than  fifty  of  these  experiments  is  the 
non-contagiousness  of  cholera,  which  we  maintained 
from  the  very  opening  of  the  discussions.  8.  The  mi- 
nute examination  made  by  us  of  the  heart  and  large  ve- 
nous vessels  of  cholera-patients  enables  us  to  affirm  that 
there  is  no  phlebocarditis  in  cholera,  as  alleged  by  Mor- 
gagni  and  still  maintained  by  many  enlightened  phy- 
sicians. 9.  Bulbar  and  medullary  lesions,  or  those  of  the 
solar  plexus,  appear  to  us  to  be  all  secondary  lesions. 
10.  In  our  opinion,  the  initial  lesion  of  cholera  takes 
place  in  the  blood.  11.  It  essentially  consists  in  the 
softening  of  the  haemoglobin,  which  makes  some  cor- 
puscles lose  first  their  clear  shape,  the  fixity  of  their 
form,  and  the  faculty  of  being  indented.  Those  cor- 
puscles adhere  together,  lengthen  rX)ut,  stick  together, 
and,  in  very  rapid  cases  especially,  some  are  seen  which 
are  quite  abnormal,  while  others  appear  quite  healthy. 
12.  The  entire  loss  of  elasticity  of  the  corpuscle  (which 
is  shown  by  the  preservation  of  the  elliptic  form  when  it 
has  been  stretched  out)  is,  in  our  view,  a  certain  sign  of 
the  patient's  death.  To  stretch  out  a  corpuscle,  it  is 
merely  needful  to  alter  the  inclination  of  a  plate  on 
which  a  sanguineous  current  has  been  established  in  the 
field  of  the  microscope.  The  fluid  column  stops  at  one 
point,  whereas  the  rest  continues  to  flow.  An  elonga- 
tion of  the  intermediary  corpuscles  results,  and  then  a 
rupture  of  the  column.  In  the  gap  thus  formed  are  some 
scattered  corpuscles.  If  these  revert  to  their  primitive 
form  the  patient  may  recover.  If  they  keep  the  elliptic 
form,  we  have  seen  death  follow  in  every  case,  even  if 
the  patient's  symptoms  were  not  serious  at  the  time  of 
the  examination  of  the  blood.  At  the  outset,  and  in  the 
rapid  cases,  which  give  the  clearest  results,  corpuscles 
remaining  healthy  are  seen  alongside  the  unhealthy  ones, 
and  assume  the  shape  well  known  in  heaps  of  money,  or 
maintain  their  liberty.  When  currents  are  created  in  the 
&Bld  of  observation,  the  columns  of  healthy,  or  less  un- 
healthy, corpuscles  remain  stationary,  or  nearly  so; 
whereas  the  unhealthy  corpuscles  flow  between  the 
columns  or  the  stationary  masses  like  fluid  lava.  This 
we  believe  to  be  the  characteristic  lesion  of  cholera. 
By  hourly  examination  of  the  blood  of  cholera-patients 
the  progress  of  the  malady  can  be  mathematically  fol- 
lowed. First  some  corpuscles  are  unhealthy,  then  one- 
third,  then  half,  Jhen  two-thirds,  and  lastly  death  super- 
venes. A  very  important  fact  in  our  view  is  that  all  the 
corpuscles  are  not  simultaneously  affected.  We  debar 
ourselves  from  substituting  a  fresh  hypothesis  for  all  those 
we  have  overthrown.  We  confine  ourselves  to  saying 
that  we  know  better  than  our  predecessors  what  the 
cholera  is  not,  but  we -do  not  know  what  it  is.'* 

The  Ambulance  Service  in  New  York. — A  corre- 
spondent of  the  British  Medical  Journal  writes :  "  Each 


of  the  principal  hospitals  of  New  York  supports  one  or 
more  ambulances,  which  may  be  called  by  the  telegraphic 
or  district  messenger  systems,  and  are  always  accom- 
panied by  a  surgeon.  During  the  year  ending  June,  1883 
Chambers  Street  Hospital  (2  ambulances)  answered  2,124 
calls ;  the  New  York  Hospital  (2  ambulances)  answered 
1,118  calls;  Bellevue  Hospital  (4  ambulances)  an- 
swered 2,606  calls;  Presbyterian  Hospital  (i  ambu- 
lance) answered  500  calls;  Roosevelt  Hospital  (2 
ambulances)  answered  750  calls ;  Ninety-ninth  Street 
Hospital  (2  ambulances)  answered  800  calls;  and  St 
Vincent's  Hospital  (2  ambulances)  answered  1,100  calls 
— ^showing'that,  during  the  time  specified,  seven  hospitals, 
supporting  fifteen  ambulances,  answered  9,198  calls." 

Death  of  Dr.  Louis  A.  Dugas. — Dr.  Louis  Alex- 
ander Dugas  died  at  his  home  in  Augusta,  Ga.,  on  Octo* 
ber  19th.  He  was  born  in  Washington,  Ga.,  January  3, 
1806.  Then  he  pursued  a  course  of  study  in  the  medical 
department  of  the  University  of  Maryland,  from  which 
he  graduated  in  1827.  He  passed  four  years  in  a  study 
of  European  medical  institutions,  and  finally  settled  down 
to  the  practice  of  his  profession  in  Augusta.  He  united 
with  five  other  physicians  in  1832  in  founding  the  Medi- 
cal College  of  Georgia,  and  accepted  the  chair  of  Pro- 
fessor of  Surgery.  He  retained  this  position  until  the 
close  of  his  life.  In  1834  he  was  elected  to  membership 
in  the  Geological  Society  of  France.  The  University  of 
Georgia  conferred  the  degree  of  Doctor  of  Laws  upon 
him  in  1869.  He  held  a  membership  in  numerous  liter- 
ary and  scientific  societies  in  Georgia,  and  was  President 
of  the  Medical  Societies  of  the  State  and  of  the  City  of 
Augusta  respectively,  for  several  years.  During  the  in- 
ternational Medical  Congress  at  Philadelphia  in  1876, 
Dr.  Dugas  was  one  of  its  Vice-Presidents.  He  became 
the  editor  of  the  Southern  Medical  and  Surgical  Journal 
in  185 1  and  retained  the  position  for  seven  years. 

Bequest  to  the  Massachusetts  General  Hos- 
pital.— The  late  Francis  P.  Hurd,  of  Wakefield,  Mass., 
bequeathed  $10,000  to  the  Massachusetts  General  Hos- 
pital. 

Hospitals  at  Winnepeg. — Dr.  Henry  H.  Chown,  of 
Winnepeg,  Manitoba,  writes  in  an  unnecessarily  indignant 
tone  regarding  an  item  in  The  Record,  which  says  that 
Winnepeg  having  a  medical  school "  is  about  to  start  a 
hospital."  Our  correspondent  says  that  the  hospital 
which  is  about  to  be  started  is  not  the  first  but  the  third 
in  that  city,  and  that  it  is  doubtful  if  any  college  has 
started  with  greater  hospital  advantages  than  the  Mani- 
toba Medical  School.  We  are  very  glad  to  learn  this,  and 
to  correct  any  misapprehension  regarding  the  educational 
facilities  of  Manitoba. 

.  "Lady  Medicals." — Such  are  the  honeyed  words 
with  which  the  Englishman  refers  to  the  women  doctors. 
A  propos  thereof  says  one  journal:  •* Although  the 
Medical  School  for  Women  in  London  has  been  open 
some  eight  or  nine  years,  only  some  score  or  so  of  lady 
doctors  have  been  launched  upon  mankind,  but  this 
limited  supply  has  far  exceeded  the  demand,  at  least  as 
far  as  England  is  concerned.  Only  about  two  or  three 
lady  doctors,  I  am  told,  can  earn  a  living  by  the  private 
practice  of  their  profession  in  this  country." 


October  25,  i884,] 


THE   MEDICAL   RECORD. 


469 


NEW  YORK  PATHOLOGICAL  SOCIETY. 

S^a/ed  Meeting,  October  8,  1884. 

George  F.  Shrady,  M.D.,  President,  in  the  Chair. 

Dr.  T.  Mitchell  Prudden  presented,  in  behalf  of  a 
candidate,  a  specimen  of  chronic  endocarditis^ 

CARCINOMA   OF  THE   STOMACH. 

Dr.  Satterthwaite  presented  the  stomach,  pancreas, 
kidneys,  and  a  portion  of  the  lungs,  removed  from  the 
body  of  a  man  fifty-three  years  of  age.    He  was  called  on 
September  7th,  in  consultation,  to  see  the  patient,  who 
had  had  a  hemiplegic  attack  of  moderate  character,  and 
from  which  he  recovered  within  twenty-four  hours  to  such 
an  extent  as  to  be  again  able  to  use  his  right  upper  and 
right  lower  extremities.     Attention  had  been  called  to 
the  fact  that  he  had  been  losing  strength  rapidly  for  six 
months,  and  on  further  inquiry  it  was  found  that  he  had 
been  losing  flesh  for  two  years.    Up  to  about  one  month 
previously  he  had  suffered  from  nothing  especially  except 
chronic  gastritis  with  frequent  attacks  of  vomiting  and 
great  difficulty  in  taking  food.     There  was  some  pain  in 
die  epigastric  region,  but  not  severe.     The  urine,  lungs, 
and  heart  were  normal.   The  epigastric  difficulty  increased 
during  the  last  month,  but  he  had  not  vomited  blood ; 
nothing  except  the  material  taken.     There  was  no  tu- 
mor in   the   epigastric  region,  although  it  was  thought 
that  some  dulness  on  percussion  could  be  detected.    The 
patient  presented  a  cachectic  appearance,  and  there  was 
progressive  emaciation  with  reduction  of  weight  from  160 
to  a  little  more  than  100  pounds. 

Two  months  after  his  first  attack  of  hemiplegia  a  sec- 
ond attack  occurred,  in  which  there  was  some  difficulty 
in  swallowing  and  speaking,  but  it  largely  disappeared, 
although  he  never  fully  recovered  his  voice  or  power  of 
swallowing  solids.  During  the  last  four  or  five  days  of 
his  life  the  patient  refused  to  eat  on  account  of  the  in- 
ability to  retain  food  and  of  the  extreme  pain  which  it 
produced,  and  he  said  that  he  preferred  Tto  starve  to 
death,  and  he  did  starve  to  death. 

On  opening  the  abdominal  cavity  the  stomach  was 
found  essentially  in  its  normal  position.  At  the  pyloric 
extremity  there  was  a  patch  of  considerable  thickening 
about  the  size  of  a  silver  half-dollar,  limited  to  the  ante- 
rior side.  The  pyloric  orifice  admitted  only  a  lead-pencil 
of  ordinary  size.  The  circular  patch  of  thickening  could 
hardly  be  appreciated  except  by  the  touch.  Although 
the  constriction  at  the  pyloric  orifice  was  not  great,  Dr. 
Satterthwaite  accounted  for  the  gastric  symptoms  on  the 
ground  that  the  thickened  portion  of  tissue  was  limited 
to  one  side,  and  was  thrown  over  the  orifice  at  times, 
acting  somewhat  like  a  valve. 

The  pancreas  was  infiltrated  with  small  nodules ;  the 
mesenteric  glands  were  somewhat  enlarged.  The  liver, 
the  lungs,  and  the  heart  were  essentially  normal  The 
kidneys  were  somewhat  fatty  and  slightly  enlarged. 

The  question  to  be  determined  was  whether  or  not 
the  thickening  at  the  pyloric  extremity  of  the  stomach 
was  due  to  malignant  disease.  Dr.  Satterthwaite  pro- 
posed to  examine  the  specimens  microscopically,  but  he 
peferrcd  to  exhibit  them  to  the  Society  while  they  were 
in  a  fresh  condition. 

The  President  asked  how  long  after  taking  food  the 
vomiting  occurred. 

Dr.  Satterthwaite  said  from  twenty-four  to  forty-eight 
hours.  The  spasmodic  efforts  during  the  attacks  of  vom- 
iting were  exceedingly  severe,  and  probably  during  some 
of  these  attacks  cerebral  hemorrhage  was  produced  suffi- 
cient to  give  rise  to  the  hemiplegia. 

Dr.  John  C.  Peters  asked  if  the  thickening  was  con- 
fined to  the  single  patch  mentioned. 
Dr.  Satterthwaite  replied  that  it  was  confined  to  the 


circular  patch  which  could  be  felt  but  not  seen,  and  in 
reply  to  another  question  said  that  the  stomach  was  not 
especially  enlarged,  although  we  might  expect  dilatation 
with  obstruction  at  the  pylorus,  yet  that  does  not  always 
occur  with  cancer. 

The  President  remarked  that  it  would  seem,  if  it  were 
malignant  disease,  it  should  have  made  more  progress 
during  the  two  years  it  had  existed. 

Dr.  Satterthwaite  remarked  that  he  had  the  records 
of  a  case  in  which  a  nodule  at  the  pyloric  orifice  of  the 
stomach  was  felt  for  two  years,  and  the  history  of  the 
tumoi;  extended  back  of  that,  and  at  the  autopsy  it  was 
proved  to  be  cancerous  in  character. 

Dr.  John  C.  Peters  thought  that  the  case  might 
prove  to  be  a  duplicate  of  the  first  case  presented  to  the 
Society  in  1844,  one  of  thickening  of  the  stomach,  which 
was  diagnosticated  during  life  as  cancer.  The  patient 
had  many  of  the  symptoms  which  Dr.  Satterthwaite  had 
mentioned,  and  there  was  found  a  hardness  in  the  walls 
of  the  stomach  without  tumor,  and  after  death  it  was  sup- 
posed to  be  cancerous.  On  examination,  however,  it 
was  found  to  be  merely  a  thickening  of  the  cellular  tissue. 
It  was  regarded  as  a  rare  specimen. 

The  President  remarked  that  it  would  be  interesting 
to  ascertain  whe.'ier  or  not  cancer  was  frequently  limited 
to  such  a  small  portion  of  the  stomach. 

Dr.  Van  Gieson  said  the  duration  of  the  disease  was 
a  very  uncertain  factor,  because  a  malignant  growth  might 
engraft  itself  upon  chronic  gastritis. 

Dr.  W.  M.  Carpenter  referred  to  a  case  in  which  he 
found  at  autopsy  a  cancerous  nodule,  about  an  inch  and 
a  quarter  in  diameter,  situated  about  three  inches  from 
the  pylorus,  upon  thf  posterior  surface  of  the  stomach,  which 
had  not  given  rise  to  symptoms.  The  patient  entered 
the  hospital  and  died  of  a  disease  not  referable  to  the 
stomach. 

Div  Satterthwaite  referred  to  a  case  in  which  he  made 
an  autopsy  and  found  a  tumor  as  large  as  an  orange, 
situated  in  the  greater  curvature  of  the  stomach,  which 
had  discharged  by  a  sinus  leading  through  the  abdominal 
wall,  and  this  sinus  had  been  treated  by  a  surgeon  with 
the  result  of  producing  a  partial  cure.  The  patient  was 
suddenly  attacked  with  gastric  symptoms  and  died.  The 
tumor  was  not  discovered  during  life,  nor  had  the  patient 
complained  of  gastric  symptoms  other  than  those  which 
were  referable  to  the  sinus  which  communicated  with  the 
growth. 

The  President  remarked  that  it  was  rather  the  rule 
than  the  exception,  when  the  disease  was  not  Ibcated  in  one 
of  the  extremities  of  the  stomach,  that  vomiting  and  other 
stomach  symptoms  did  not  develop,  and  that  the  growth 
was  discovered  only  at  autopsy. 

NASO-PHARYNGEAL   FIBRO-SARCOMA. 

Dr.  R.  p.  Lincoln  presented  a  specimen  with  the  fol- 
lowing history  (see  page  455)  :      * 

The  President  remarked  that  there  was  no  compari- 
son between  the  operation  described  by  Dr.  Lincoln  and 
that  with  preliminary  tracheotomy,  tamponing  the  pha- 
rynx, and  removing  the  upper  jaw.  There  could  be  no 
argument  against  the  success  obtained  in  Dr.  Lincoln's 
case. 

Dr.  Howe  thought  that  it  afforded  a  strong  argument 
against  the  use  of  the  knife  in  all  of  these  cases. 

The  President  remarked  that  in  some  cases  the  wire 
could  not  be  applied  to  the  base  of  the  tumor  so  as  to 
grasp  it.  He  had  had  two  such  cases,  in  one  of  which 
Dr.  Howe  assisted  at  the  operation,  and  in  which  pre- 
liminary tracheotomy  was  performed,  the  pharynx  tam- 
poned, and  the  upper  jaw  removed.  It  was  found  that 
the  tumor  had  prolongations  extending  up  into  the  skull 
through  the  foramen  lacerum  medius,  and  from  this  cir- 
cumstance he  had  been  enabled  to  explain  the  shock 
which  ultimately  caused  the  patient's  death.  The  tumor 
was  extensively  attached  to  the  basilar  process  and  to  ad- 
joining portions  of  the  base  of  the  skull  in  various  direc- 


470 


THE  MEDICAL  RECORD. 


[October  25, 1884. 


tions.  In  that  case,  however^  the  application  of  the  wire 
was  found  to  be  impossible. 

The  second  case  was  one  in  which  there  were  almost 
as  extensive  attachments  of  the  growth,  and  the  opera- 
tion was  followed  by  the  same  result,  although  death  did 
not  take  place  as  soon  as  in  the  first  case.  He  also  had 
another  patient  who  was  begging  for  a  similar  operation, 
a  man  twenty-two  years  of  age,  and  concerning  whom  he 
had  promised  himself  the  pleasure  of  a  consultation  with 
Dr.  Lincoln  as  to  the  feasibility  of  the  use  of  the  galvano- 
cautery.  The  great  trouble  with  most  of  these  cases  was 
that  they  did  not  reach  the  general  surgeon  until  they  were 
beyond  all  hope  of  removal  by  the  wire,  and  they  were 
also  in  a  very  unfavorable  general  condition  for  the  radi- 
cal operation.  There  could,  therefore,  be  no  argument 
against  success  in  such  cases,  however  obtained. 

Dr.  Howe  suggested  that,  even  in  the  bad  cases  spo- 
ken of,  before  any  attempt  was  made  to  remove  the 
tumor  by  the  knife,  efforts  might  be  made  to  destroy  it 
piecemeal  by  means  of  the  wire.  He  could  not  see  why 
it  could  not  be  done  there  as  well  as  elsewhere. 

The  President  remarked  that  the  difficulty  consisted 
in  the  inability  to  get  hold  of  pieces  of  sufficient  size. 
Within  the  last  year  he  had  had  a  patient  under  observa- 
tion, and  had  sent  him  to  a  gentlem'*  .1  well  skilled  in 
this  method  of  operating,  who  succeeded  in  removing 
small  pieces,  but  left  the  patient  in  such  a  deplorable 
condition  from  subsequent  inflammation  that  he  declined 
to  have  the  operations  repeated. 

Dr.  Satterthwaite  said  that  it  seemed  to  him  that 
Dr.  Lincoln's  operation  was  an  extremely  brilliant  one, 
and  was  one  which  required  and  obtained  a  great  deal  ojf 
manual  dexterity  in  preventing  the  mre  from  twisting, 
and  also  in  adjusting  it  to  the  base  of  the  tumor.  Dr. 
Lincoln  passed  the  wire  all  the  way  down  to  the  basilar 
process  and  removed  the  entire  growth  at  one  operation. 
It  had  been  said  by  one  distinguished  throat  specialist 
who  saw  the  case  that  the  operation  could  not  be  per- 
formed, and  that  removal  of  the  upper  jaw  would  be 
necessary.  Dr.  Satterthwaite  thought  that  fact  should 
be  borne  in  mind  in  estimating  the  brilliancy  and  feasi- 
bility of  the  operation ;  and  also  the  additional  fact  should 
be  recollected  that  this  was  only  one  of  three  or  four 
cases  in  which  Dr.  Lincoln  had  removed  large  naso- 
pharyngeal polypi,  and  in  none  of  them  had  the  disease 
returned. 

In  his  hospital  notes  he  had  not  found  the  records  of 
a  case  in  wh|ch  the  disease  had  not  returned  and  the 
patients  had  been  subject  to  hemorrhages,  etc.  But  the 
patient  upon  whom  Dr.  Lincoln  operated  and  removed 
the  specimen  presented  had  gained  flesh  remarkably, 
and  had  not  had  any  hemorrhages  whatever.  In  these 
cases  the  galvano-cautery  is  peculiarly  successful  be- 
cause it  arrests  hemorrhage  and  destroys  the  tissue  to 
such  an  extent  that  if  (he  growth  return,  hemorrhage  is 
not  likely  to  ensue  from  the  use  of  the  wire.  He  thought 
too  much  could  not  be  said  in  favor  of  this  mode  of 
operating,  and  he  would  be  pleased  to  hear  from  Dr. 
Lincoln  as  to  what  his  success  had  been. 

Dr.  Lincoln  said  he  had  operated  in  six  cases.  Two 
of  the  patients  were  still  under  treatment.  Of  the  other 
four  cases,  one  was  operated  upon  in  1874,  one  in  1875, 
one  in  1879,  ^"^  o"®  ^^  1880.  He  thought  there  was 
no  possibility  of  recurrence  in  any  of  these  four  cases. 
He  had  not  had  any  fatal  cases. 

With  regard  to  the  operation,  he  would  refer  to  the  one 
which  he  performed  in  1875.  ^^  seemed  to  be  as  ex- 
treme a  case  as  could  possibly  exist.  The  patient  had 
been  operated  upon  by  Dr.  Willard  Parker,  and  also  by 
Dr.  Lutkins,  of  Jersey  City,  who  sent  him  to  Dr..  Lincoln. 
The  patient  was  a  boy  ten  years  of  age,  who,  when  he 
saw  him,  weighed  sixty-eight  pounds,  and  death  seemed 
inevitable.  The  growth  had  caused  the  right  eye  to  pro- 
trude a  great  deal,  the  right  nostril  was  very  broad  at  the 
base,  the  mouth  was  so  filled  that  the  uvula  was  carried 
orward  to  aii  extent  that  if  the  incisor  teeth  could  have 


been  closed  they  would  have  cut  it  ofi*,  and  in  general 
condition  he  was  reduced  to  extremis.  Dr.  Lincoln 
made  a  preliminary  treatment  by  electrolysis,  with  some 
twenty  or  twenty-five  applications,  and  the  result  was 
arrest  of  the  growth,  preventing  hemorrhages,  and  reduc- 
ing the  mass  to  such  a  size  as  to  give  the  patient  a  chance 
to  recuperate  preparatory  for  the  radical  operation.  At 
the  time  he  operated,  in  1876,'the  boy  weighed  one  hun- 
dred and  three  pounds,  and  the  tumor  had  largely  dis- 
appeared from  the  mouth.  He  removed  the  growth  in 
the  manner  already  described,  and  without  any  hemor- 
rhage. He  made  six  applications  with  the  galvano- 
cautery  to  the  stump  at  invervals  of  one  or  two  weeks. 
There  had  been  no  return  of  the  disease.  There  were 
extensive  adhesions  of  the  growth  to  the  back  of  the 
pharynx  and  the  sides  of  the  nostrils. 

In  another  case  there  were  prolongations  of  the  growth 
to  such  an  extent  that  the  tumor  appeared  under  the 
cheek  as  large  as  a  pullet's  egg.  This  patient  was  oper- 
ated  upon  in  the  same  manner,  was  put  upon  the  same 
after  treatment.  The  result  was  the  entire  disappearance 
of  the  prolongations  of  the  growth  in  the  face,  and  the 
patient  is  now  perfectly  well.  The  other  cases  were 
similar,  but  not  so  pronounced. 

Dr.  Van  Gieson  asked  if  in  the  case  operated  upon 
in  1876,  where  the  tumor  protruded  so  extensively  into 
the  mouth,  if  Dr.  Lincoln  was  able  to  remove,  the  whole 
of  the  mass  through  the  mouth  without  dividing  it 

Dr.  Lincoln  answered  that  the  entire  tumor  was  re- 
moved through  the  mouth. 

The  President  remarked  that  he  was  so  favorably 
impressed  with  this  operation  that  he  should  not  try  any 
other  without  first  attempting  to  use  the  wire,  and  fur- 
ther, that  no  small  degree  of  credit  was  due  to  Dr.  Lin- 
coln for  demonstrating  this  comparatively  simple  and  yet 
radical  operation. 

FIBRO-CVST  OP  THE  UTERUS. 

Dr.  T.  Mitchell  Prudden  presented  a  specimen  for 
which  he  was  indebted  to  the  courtesy  of  Dr.  C.  C.  Stock- 
ard,  of  Columbus,  Miss.  The  case  has  already  been  re- 
ported.    (See  The  Medical  Record,  August  16, 1884.) 

Dr.  Prudden  had  submitted  the  growth  to  microscop- 
ical examination ;  found  it .  to  be  composed  of  smooth 
muscular  and  fibrous  tissue,  presenting  very  much  the  ap- 
pearance seen  in  the  ordinary  fibromyomata  of  the  uterus. 
There  was  no  distinct  cellular  lining  of  the  cavity  of  the 
tumor.  He  presented  the  specimen  because  of  its  size 
and  because  it  was  interesting  as  showing  one  of  the 
modes  of  formation  of  cysts,  namely,  softening,  and  per- 
haps dilatation  of  the  original  solid  tumor  by  the  accumu- 
lation of  fluid  and  disintegration  of  tissue.  The  entire 
weight  of  the  mass,  as  reported  by  Dr.  Stockard,  was  one 
hundred  and  thirty-five  pounds. 

Dr.  Ferguson  remarked  that  he  had  just  come  from 
a  post-mortem  examination  in  which  he  removed  a  tumor 
weighing  more  than  the  one  presented.  It  was,  however, 
an  ovarian  tumor. 

Dr.  Castle  referred  to  the  case  of  a  patient  who  died 
in  Bellevue  Hospital,  where,  owing  to  the  failure  of  tak- 
ing proper  precautions,  the  woman  by  some  of  her  move- 
ments caused  the  tumor  to  fall  out  of  bed  and  it  dragged 
the  patient  with  it. 

Dr.  Wilcox  asked  with  regard  to  the  frequency  of  the 
occurrence  of  uterine  fibro-cysts  in  the  negress. 

Dr.  Prudden  said  that  large  tumors  like  this  were 
rare,  but  that  small  tumors  were  not  at  all  infrequent 

Dr.  Castle  remarked  that  it  had  been  said  to  be  tiw 
rule  rather  than  the  exception  to  find  fibrous  tumors  of 
the  uterus  in  the  negress. 

intestinal  obstruction — uterine  fibroids. 

Dr.  C.  W.  Knight  presented  a  specimen  with  the  fi^ 

lowing  history :  A.  B ,  colored,  unmarried,  thirty-fi« 

years  of  age,  has  always  been  constipated,  and  has  hw 
frequent  attacks  of  severe  "  colic "  (?) ;  has  never  bad 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


471 


occasion  to  call  a  doctor  for  these  or  for  other  illness. 
Bowels  have  not  moved  for  nearly  three  weeks.     Five 
(jays  ago  began  to  take  purgatives,  and  has  used  them 
since  in  great  variety,  without  eflfect     Stomach  became 
swollen,  and  three  days  ago  vomiting  began.     Called  a 
physician,  who  gave  a  cathartic     No  constitutional  dis- 
turbance was  noticed,  although  there  was  intense  thirst 
Vomiting  became  more  frequent ;  the  vomited  matter 
was  fluid  and  had  a  greenish  color.     During  the  last 
twelve  hours  of  life  "  several  quarts  "  were  vomited,  the 
jMomen  became  enormously  distended,  and  respiration 
was  greatly  impeded.     Death  took  place  suddenly  as  the 
patient  was  attempting  to  rise  from  bed.     The  patient 
had  been  walking  about  her  room  nearly  all  day,  making 
DO  complaint  of  pain,  but  suffering  great  discomfort  from 
the  vomiting  and  the  distention  of  the  abdomen.  Enemata 
of  various  kinds  were  resorted  to,  but  they  brought  away 
only  a  few  scybalous  masses.     On  opening  the  abdomen 
the  small  intestines,  intensely  congested  and  distended, 
were  exposed.      The   colon   was  found  nearly  empty. 
About  five  inches  from  the  caecum  the  ileum  was  found 
constricted  by  a  band  of  tissue  running  between  two 
Qterine  fibroids.     The  loop  of  intestine  was  five  to.  six 
inches  in  length,  was  almost  black,  and  was  distended 
with  gas ;  it  was  easily  emptied  and  pushed  back  through 
the  constricting  band.     There  was  no  ulceration,  but  the 
points  of  constriction  were  indicated  by  deep  furrows  in 
the  wall  of  the  intestine.     The  uterine  fibroids,  mural 
and  sub-peritoneal,  four  or  five  in  number,  vary  in  size 
from  that  of  a  hickory-nut  to  that  of  a  small  orange. 
They  and  the  caecum  and  the  first  five  or  six  inches  of 
the  ileum  were  matted  together  by  old  peritonitis.  There 
was  no  ulceration  of  the  intestine,  and  recent  peritonitis 
was  limited  to  the  region  of  the  strangulation. 
The  Society  then  went  into  executive  session. 


THE  NEW  YORK  ACADEMY  OF  MEDICINE. 
Stated  Meeting y  October  i$,  1884. 

FoRDYCE  Barker,   M.D.,  LL.D.,  President,  in  the 
Chair. 

Dr.  Harry  Marion  Sims  presented  a 

BRONZE    BUST  OF  THE  LATE  J.  MARION   SIMS,  M.D.,  LL.D., 

copied  from  a  marble  bust  made  by  Dubois,  the  celebraf- 
ted  French  sculptor.     It  is  a  most  life-like  figure. 

The  President,  in  behalf  of  the  Academy,  accepted 
the  gift  with  appropriate  remarks. 

Dr.  Wm.  T.  White  offered  a  resolution  tendering 
the  thanks  of  the  Academy  to  the  donor  for  his  beautiful 
and  highly  acceptable  gift. 

Dr.  John  Scott,  of  San  Francisco,  was  introduced  to 
the  Academy  and  invited  to  a  seat  upon  the  platform. 

Dr.  Wm.  H.  Draper  then  delivered  a 

MEMOIR    OF    the    LATE   WILLARD   PARKER,   M.D.,  LL.D., 

in  which  he  paid  a  worthy  tribute  to  the  distinguished 
citizen,  the  skilful  surgeon,  and  the  upright  man  whose 
"face  was  always  set  before  the  light." 

THE  THERAPEUTICAL  EFFECTS  OF  THE  INTERNAL  ADMINIS- 
TRATION OF  HOT  WATER  IN  THE  TREATMENT  OF  NERV- 
OUS  DISEASES. 

Dr.  a.  L.  Ranney  read  a  paper  with  the  above  title, 
in  which  he  maintained  that  the  benefits  following  the 
internal  use  of  hot  water  were  due  almost  entirely  to  heat, 
and  gave  the  following  rules  for  its  administration  : 

1.  An  ordinary  goblet  contains  about  ten  ounces,  and 
the  quantity  may  be  from  one  to  one  and  a  half  goblet 

2.  The  water  may  be  flavored  with  lemon,  etc. ;  fifteen 
minutes  may  be  consumed  in  sipping  a  gobletful ;  wooden 
cups  prevent  it  from  cooling  quickly ;  and  it  must  be 
aken  hot  and  not  warm — from  no®  to  150°  F. 

3.  It  must  be  taken  one  hour  and  a  half  before  each 
Deal,  with  absolute  punctuality,  and  at  bed-time. 


4.  Increase  the  temperature  of  the  water  as  fast  as  the 
patients  can  bear  it. 

5.  The  administration  of  hot  water  must  be  continued 
for  at  least  six  months  to  get  its  full  effects. 

6.  The  dose  should  be  determined  largely  by  the 
specific  gravity  and  general  character  of  the  urine.  The 
object  is  to  bring  the  specific  gravity  of  the  urine  to 
the  standard  of  health. 

7.  The  use  of  cold  fluids  in  the  form  of  beverages 
must  be  absolutely  prohibited. 

8.  Constricted  diet  is  often  necessary  to  the  full  effects 
of  the  treatment  in  some  form  of  nervous  derangements. 

The  effects  of  the  treatment  were  set  forth  as  follows  : 
I,  the  first  effect  is  the  production  of  a  sense  of  warmth 
in  the  stomach,  attended  by  eructation  of  gas  not  infre- 
quently ;  2,  the  skin  soon  shows  the  effect  of  the  heat ; 
3,  the  kidneys  exhibit  marked  effects,  and  very  soon  the 
quantity  of  urine  is  increased.  On  the  other  hand,  in  dia^ 
betes  the  quantity  of  urine  is  diminished  ;  4,  the  acces- 
sory organs  of  digestion,  the  pancreas,  and  the  liver  are 
stimulated,  and  flatulence  and  constipation  seem  to  be 
relieved. 

The  author  of  the  paper  then  referred  briefly  to  the 
histories  of  several  cases  of  different  diseases  which  he 
had  treated  by  the  internal  administration  of  hot  water, 
perhaps  combined  with  other  remedial  agents. 

Among  these  were  locomotor  ataxia,  neurasthenia, 
gastralgia,  local  anaemia  of  the  brain  with  transient 
aphasia,  etc. 

The  theory  of  its  action  which  the  author  of  the  paper 
advanced  was  that  the  nerves  of  the  stomach,  possibly 
the  solar  plexus,  were  directly  influenced  by  the  heat  in- 
troduced into  the  empty  organ.  He  believed  that  ice- 
water  did  more  harm  than  tobacco  and  alcohol. 

Dr.  Ranney  reached  the  following  conclusions  :  (i) 
The  plan  of  treatment  is  harmless;  (2)  its  effects  are 
comparatively  uniform  when  given  for  a  suflicient  length 
of  time ;  (3)  it  seems  to  exert  a  curative  influence  in 
many  chronic  diseases ;  (4)  it  appears  that  the  curative 
influence  of  hot  water  is  not  transient ;  (5)  it  may  be  em- 
ployed as  an  adjunct  without  detriment  to  the  influence 
produced  by  other  therapeutical  agents;  (6)  it  has  a 
marked  influence  on  the  vascular  disturbances  of  the 
nervous  system  ;  (7)  in  diabetes  and  some  kidney  affec- 
tions he  had  seen  it  exert  a  marked  influence  for  good, 
and  the  specific  gravity  of  the  urine  had  been  his  guide 
in  estimating  the  effects  produced  ;  (8)  as  a  laxative  it 
has  a  slow  but  decided  action  ;  (9)  the  skin  is  stimulated 
and  the  cutaneous  circulation  rendered  more  uniforai. 

The  author  of  the  paper  also  recommended  the  use  of 
hot  water  in  sea-sickness. 

Dr.  £.  C.  Sequin  had  had  but  little  experience  in  the 
use  of  hot  water,  and  had  never  employed  it  in  the  treat- 
ment of  purely  organic  disease  of  the  nervoUs  system. 
He  had  been  struck  with  several  points  in  the  paper 
which  seemed  to  him  to  be  open  for  discussion,  and  per- 
haps for  some  degree  of  question.  First,  as  to  the  quality 
of  the  agent.  It  seemed  to  him  that  a  temperature  of 
II  o**  to  150°  F.  would  hardly  justify  classifying  hot  water 
as  a  really  heating  agent,  the  internal  temperature  of  the 
human  body  being  about  100°  F. 

In  the  second  place,  as  to  the  cases  brought  forward 
by  the  author  of  the  paper,  a  large  proportion  of  them 
seemed  to  be  cases  of  neurasthenia,  so-called  cerebral 
hyperaemia,  anaemia,  etc.  Many  of  them  constituted  one 
of  the  most  doubtful  classes  in  our  classification  of  disease. 
Most  of  these  disorders,  certainly  many  of  those  com«> 
monly  called  cerebral  hyperaemia  and  cerebral  anaemia, 
were  nothing  more  than  cases  of  mal-assimilation  in  which 
the  digestive  orgiins  were  at  fault,  and  in  these  cases  Dr. 
Ranney  had  employed  a  combined  treatment ;  combining 
hot  water  with  strict  regulation  of  the  diet,  and  in  some 
instances  restriction  to  a  purely  meat  diet. 

Dr.  Seguin  suggested  a  question,  namely  :  Was  it  not 
possible  that  the  beneficial  effect  produced  in  Dr. 
Ranney's  cases  was  due  to  water  and  not  to  hot  water  ? 


472 


THE  MEDICAL  RECORD. 


[October  25, 


Many  patients  had  a  lack  of  desire  for  water — what  Dr. 
McEiroy,  of  Zanesville,  Ohio,  had  called  hydroadypsia, 
and  many  of  the  symptoms  of  spinal  irritation,  so -called 
cerebral  hyperasmia,  neurasthenia,  etc,  could  be  largely 
relieved  by  the  internal  administration  of  ordinary  water. 
Hot  water  might  do  good  as  water  in  aiding  assimilation, 
but  it  might  be  a  question  whether  or  not  the  benefit 
resulting  was  due  to  anything  more  than  the  water. 

With  respect  to  the  use  of  hot  water  in  organic  nervous 
disease,  he  had  had  no  experience. 

Concerning  the  theory  advanced  by  the  author  of  the 
paper,  namely,  that  the  water  produces  its  beneficial 
effect  through  reflex  action,  Dr.  Seguin  thought  there 
might  be  some  foundation  for  it ;  but  at  the  same  time,  if 
a  share  of  the  good  effect  was  to  be  attributed  to  the 
liquid,  the  share  which  could  be  attributed  to  the  effect 
produced  by  the  heat  was  not  very  great.  He  doubted 
if  the  degree  of  heat  was  sufficient  to  produce  more  than 
temporary  hyperaemia  of  the  mucous  membrane  of  the 
stomach. 

He  offered  a  word  in  defence  of  cold  water,  and  saw 
no  objection  to  the  use  of  ice-water  upon  the  same  prin- 
ciple with  which  he  questioned  the  degree  of  heat.  He 
did  not  believe  that  ice- water,  ice-cream,  etc.,  were 
exceedingly  cold  when  they  reached  the  stomach,  for  they 
received  a  large  amount  of  heat  in  their  passage  through 
the  mouth  and  oesophagus. 

In  point  of  fact,  he  had  obtained  just  the  same  results 
by  the  use  of  ordinary  water  as  those  which  Dr.  Ranney 
had  obtained  by  the  use  of  hot  water,  and  he  gave  it  with 
the  meals. 

Dr.  R.  W.  Amidon  had  had  no  experience  in  the  use 
of  hot  water  in  purely  nervous  diseases,  but  in  the  treat- 
ment of  nervous  phenomena  such  as  attended  certain 
cases  of  dyspepsia,  ansemia,  particularly  associated  with 
the  rheumatic  or  gouty  diathesis,  he  had  employed  it  to 
some  extent.  He  regarded  the  derivative  action  of  hot 
water  as  extremely  doubtful.  Moreover,  Dr.  Ranney 
had  said  that  no  beneficial  effects  were  to  be  expected 
until  six  months  had  elapsed,  but  according  to  his  experi- 
ence no  counter-initant  or  derivative  acted  as  slowly  as 
this. 

He  believed  that  water  acted  mainly  on  account  of  its 
diluent  qualities,  and  especially  so  when  the  vascular  sys- 
tem was  depleted,  as  it  was  in  many  if  not  most  of  the 
class  of  cases  in  which  beneficial  effects  had  been  ob- 
tained by  its  use.  That  it  might  act  as  a  tonic,  produc- 
ing its  effects  slowly,  might  be  explained  on  the  ground 
of  gradual  improvement  of  the  powers  of  assimilation  in 
accordance  with  well-established  chemico-physiological 
laws. 

Dr.  L.  Putzel  had  had  no  experience  in  the  use  of 
hot  water,  but  thought  that  the  experience  advanced  by 
the  author  of  the  paper  proved  too  much ;  for  it  had 
been  stated  that  hot  water  was  efficacious  in  cerebral 
hyperaemia  and  cerebral  anaemia,  and  if  it  produced  any 
effect,  which  was  altogether  unproven,  it  could  not  be 
beneficial  in  opposite  conditions. 

He  thought  some  stress  should  be  laid  upon  the  point 
made  by  Dr.  Amidon,  namely,  that  therapeutic  agents  of 
this  kind  act  quickly.  Hot  water  should  act  best  at  first, 
if  Dr.  Ranney' s  theory  was  correct.  Dr.  Putzel  was  un- 
able to  see  how  any  agent  which  acted  in  this  manner 
could  possibly  have  any  effect  upon  such  organic  disease 
of  the  nervous  system  as  locomotor  ataxia,  and  he  should 
be  very  much  inclined  to  regard  the  improvement  which 
Dr.  Ranney  had  reported  in  these  cases  as  due  to  the  law 
of  coincidence. 

Dr.  W.  R.  Birdsall  believed  that  there  was  con- 
siderable efficacy  in  the  use  of  hot  water,  as  well  as  cold 
water.  He  was  not  prepared  to  deny  the  agency  of  heat 
in  the  use  of  hot  water,  and  believed  that  it  was  one  of 
the  principal  agents  in  producing  its  therapeutical  effects. 
What  he  had  wished  to  hear  from  the  author  of  the  paper 
was  statistics  of  a  clear  character,  but  unfortunately  in 
all  of  the  cases  reported  quite  a  complicated  plan  of 


treatment  had  been  adopted,  consisting  in  a  combination 
of  agents,  nearly  all  of  which  had  been  found  more  or 
less  beneficial  in  the  treatment  of  the  dbeases  under  con- 
sideration. Certainly  no  use  could  be  made  of  those 
cases. 

With  regard  to  the  use  of  hot  water  in  the  treatment 
of  functional  disturbances  of  the  nervous  system,  there 
were  always  so  many  complicating  influences  that  it 
would  be  a  long  time  before  we  could  separate  the  thera- 
peutical action  from  the  mere  diluent  action  of  the  water. 
Still  he  believed  that  heat  played  an  important  part  in 
producing  irritation  of  the  mucous  membrane. 

Dr.  C.  L.  Dana  had  used  hot  water  in  the  tr«itment 
of  chronic  functional  nervous  diseases,  chiefly  in  hys- 
terical women  with  S3m[iptoms  of  gastric  disturbance,  and 
had  been  disappointed  in  the  results.  Perhaps  the  fail. 
ure  to  obtain  benefit  was  due  to  the  lack  of  care  in  its 
administration,  so  minutely  urged  by  the  reader  of  the 
paper. 

Many  years  ago  Dr.  Wilkes  had  demonstrated  that  the 
best  results  had  been  obtained  by  the  use  of  agents 
which  did  not  act  upon  the  nervous  system  specifically, 
and  therefore  it  was  altogether  probable  that  the  line  of 
treatment  laid  down  by  the  author  of  the  paper  was 
likely  to  prove  extremely  useful. 

Dr.  J.  L.  Corning  had  used  hot  water  in  the  treat- 
ment of  digestive  disturbances  concomitant  with  func- 
tional diseases  of  the  nervous  system,  such  as  neuras- 
thenia, etc.,  and  had  obtained  good  results.  He  had  no 
theory  to  offer  with  regard  to  the  action  of  the  agent, 
but  could  not  agree  with  Dr.  Ranney  that  the  good  re- 
suits  were  deferred  for  six  months,  for  he  had  seen  benefit 
follow  within  six  weeks  or  two  months. 

Dr.  John  Scott,  of  San  Francisco,  first  visited  the 
Academy  in  1866,  when  he  had  the  pleasure  of  listening 
to  a  paper  and  discussion  participated  in  by  our  honored 
president.  His  next  visit  to  the  Academy  was  at  this 
meeting,  and  he  had  been  querying  in  his  own  mind  as 
to  how  it  was  the  president  maintained  his  perpetual 
youth.  On  confidential  inquiry,  however,  he  had  learned 
to  his  intense  satisfaction  that  it  had  been  maintained 
largely  through  the  agency  of  hot  water.  He  was  not 
aware  when  he  came  to  the  meeting  that  the  paper  was 
to  have  any  special  political  significance,  but  it  might  be 
said  to  have  taken  such  a  turn,  and  as  to  what  its  im- 
mediate or  remote  effect  would  be  upon  the  result  of  the 
political  canvass  was  not  easy  to  say ;  perhaps  the  paper 
might  be  regarded  as  a  political  speech  in  favor  of  St. 
John.  He  had  queried  also  as  to  what  was  to  become 
of  all  of  the  doctors  and  the  druggists,  should  the  plan  of 
treatment  advocated  so  ably  by  the  author  of  the  paper 
be  carried  into  full  effect. 

During  the  last  thirty  years  he  had  used  hot  water  for 
a  variety  of  affections,  but  chiefly  for  checking  emesis, 
especially  that  which  occurs  after  the  administration  of 
ether.  He  had  also  employed  it  in  the  treatment  of  a 
large  variety  of  affections,  changed  somewhat  in  color 
to  be  sure,  and  more  especially  in  the  form  known  as 
milk,  and  he  believed  that  he  had  obtained  equally  good 
results  as  those  which  had  been  presented  by  Dr. 
Ranney. 

Dr.  T.  H.  Burchard  asked  the  author  of  the  paper, 
first,  if  he  had  seen  any  serious  or  permanent  injury  done 
to  the  digestive  apparatus  by  the  long-continued  use  of 
hot  water,  and,  second,  whether  he  had  noticed  that  the 
hot-water  treatment  had  developed  a  predisposition  to 
intestinal  and  gastric  hemorrhages.  He  had  had  oppor- 
tunity to  see  a  large  number  of  patients  who  had  been 
following  this  plan^of  treatment  quite  faithfully,  and  in 
quite  a  proportion  of  them  he  had  encountered  the  per- 
manent digestive  disorders  alluded  to,  and  also  the 
tendency  to  the  occurrence  of  internal  hemorrhage. 

Dr.  Ranney,  closing  the  discussion,  said  he  had  not 
seen  any  cases,  either  of  internal  hemorrhage  or  per- 
manent impairment  of  the  digestive  oi^ns,  alluded  to  by 
Dr.  Burchard.     He  had  seen  people  who  had  been  re- 


October  25,  1884.J 


THE  MEDICAL  RECORD. 


473 


duced  in  flesh  rapidly  by  the  use  of  hot  water  with 
restricted  diet,  but  this  was  purposely  done,  and  when 
the  treatment  had  been  discontinued  they  immediately 
began  to  gain  in  weight. 

He  thought  Dr.  Seguin's  criticism  with  reference  to 
the  degree  of  heat  was  not  valid  when  the  water  was 
taken  as  he  had  directed — taken  in  teaspoon ful  doses  as 
hot  as  the  patient  could  swallow,  less  than  110°  F.  never 
being  used.  Dr.  Seguin's  theory  that  ice-water  would 
lose  heat  in  its  transmission  to  the  stomach,  when  applied 
to  the  use  of  hot  water  would  increase  the  heat,  and 
therefore  increase  the  efficacy  of  the  agent. 

The  effects  produced  by  the  agent  were  as  immediate 
as  they  could  be ;  sometimes  it  took  six  weeks  to  get 
marked  effects,  and  sometimes  it  took  six  months  to  get 
the  best  effects*  Certainly  he  did  not  mean  to  say  it 
lequired  six  months  to  get  any  effects  from  the  use  of  hot 
water. 

The  double  action  of  the  water — that  is,  the  beneficial 
effects  produced  in  cerebral  hyperaemia  and  also  in  cere- 
bral anaemia,  could  be  very  easily  explained  on  the 
ground  that  the  tendency  of  the  agent  was  to  restore  the 
vascular  apparatus  to  the  normal  condition,  and  there- 
fore it  might  prove  beneficial  in  either  abnormal  con- 
(Stion. 

So  far  as  his  theory  concerning  the  action  of  the  agent 
was  concerned,  it  might  be  totally  incorrect.  He  simply 
advanced  it  as  one  which  was  plausible,  and  as  the  one 
which  seemed  to  him  best  to  explain  the  action  of  the 
agent 

Of  course  he  had  no  clear  statistics  to  publish.  He 
had  simply  mentioned  a  few  results,  had  brought  forward 
a  few  cases  in  which  he  had  tried  the  agent  after  well- 
recognized  methods  of  treatment  had  proven  ineffectual. 
Complete  statistics  could  be  obtained  only  after  a  more 
continued  employment  of  the  hot  water  in  distinct  classes 
of  cases. 

HYDROCHLORATK   OF    COCAINE   AS   A   LOCAL   ANiESTHETIC 
TO   THE   CORNEA. 

Dr.  C.  R.  Agnew  directed  the  attention  of  the  Acad- 
emy to  the  local  use  of  this  agent,  and  demonstrated  its 
anaesthetic  action  by  applying  a  two  per  cent,  watery  so- 
lution to  the  scleral  conjunctiva  of  two  persons.  Since 
the  publication  of  the  interesting  letter  of  Dr.  H.  D. 
Noyes,  which  appeared  in  The  Medical  Record  for 
October  11,  1884,  he  had  employed  it  in  fifteen  or  six- 
teen cases,  and  with  results  which  had  been,  both  to  ob- 
servers and  to  himself,  most  satisfactory  and  astonishing. 
At  the  present  time  he  felt  that  nothing  had  been  given 
to  surgery  of  greater  importance  since  the  introduction 
of  ether.  It  was  yet  to  be  demonstrated  whether  the 
agent  when  dropped  into  a  wound  would  produce  local 
anaesthesia.  He  distinctly  disavowed  any  attempt  to 
claim  priority  in  its  use  in  this  city,  but  wished  merely  to 
demonstrate  its  marvellous  effects  to  the  Academy. 

Dr.  Burchard  had  seen  a  case  of  felon  in  which  the 
finger  was  immersed  in  a  solution  of  cocaine,  and  local 
anaesthesia  was  produced  so  that  the  patient  suffered  no 
pain  when  the  finger  was  opened  with  the  knife. 

Dr.  Birdsall  spoke  of  the  benumbing  effects  produced 
upon  mucous  membranes  by  erythroxylon  coca. 

The  President  referred  to  the  use  of  the  fluid  ex- 
tract of  coca  for  strengthening  the  vocal  cords  and  im- 
proving the  voice. 

The  Academy  then  adjourned. 


(£^owtBpon&jmcii. 


A  Society  for  Psychical  Research. — An  attempt 
is  being  made  in  Boston  to  organize  a  society  for  psychi- 
cal research  ;  1.^.,  for  the  study  of  mind-reading,  spiritual- 
ism, mesmerism,  etc.  It  may  not  be  generally  known 
that  a  similar  society  exists  in  this  city,  under  the  modest 
title  of  **  The  Academy  of  Anthropology." 

MiDWivES  in  Buffalo,  N.  Y. — Two-thirds  of  the  ob- 
stetrical cases  reported  in  Buffalo,  N.  Y.,  are  said  by  Dr. 
Pryor  to  be  attended  by  midwives. 


A  PLEA  FOR  THE  COUNTRY  PRACTITIONER. 

To  THB  Editor  or  Thb  Mkdical  Rscokd. 

Sir  :  In  your  editorial  on  •*  The  Importance  of  Holiday 
Seasons  for  Physicians,"  you  state  that  "the  city  physician 
is  subjected  to  causes  of  ill-health  from  which  his  country 
confrire  is  comparatively  exempt;'*  that  "the  latter 
breathes  purer  air  and  has  invigorating  rides  over  hill  and 
plain/'  etc.  Having  had  about  ten  years'  experience  in 
such  invigorating  work)  I  think  I  can  speak  from  experi- 
ence. There  are  no  harder  worked  physicians  on  earth 
than  the  country  doctor,  with  a  large  practice,  and  none 
that  needs  vacations  more.  His  long  rides  expose  him  to 
every  kind  of  weather,  and  there  is  hardly  a  storm  but 
what  he  is  caught  out  in  it.  The  roads  in  country  dis- 
tricts where  there  are  no  pikes  get  almost  impassable  in 
rainy  wmters,  and  we  generally  have  it  very  wet  every 
alternate  winter  here  in  Central  Ohio.  I  have  known 
the  roads  to  break  up  and  remain  so  from  October  until 
May,  not  frozen  so  you  could  drive  a  wheeled  vehicle  a 
dozen  days  during  the  winter — mud  often  to  the  horse's 
knees  from  fence  to  fence.  The  consequence  is  that  we 
are  obliged  to  ride  horseback,  a  very  laborious  way, 
especially  if  indulged  in  for  five  or  six  months,  almost 
night  and  day.  The  fact  is,  that  a  great  many  country 
doctors  find  long  rides  so  intensely  invigorating  that  they 
have  to  quit,  or  go  to  the  city  in  order  to  get  that  rest  so 
much  needed  by  the  hard-worked  practitioner. 

It  costs  but  little  more  to  live  in  the  city  than  the 
country  when  we  take  into  consideration  the  amount  that 
the  country  doctor  pays  for  his  medicine,  and  the  number 
of  horses  it  requires  to  ride  over  a  big  scope  of  country. 
He  can't  get  along  with  less  than  two,  and  to  do  justice 
to  the  horses  he  needs  four  more  often. 

The  competition  in  this  part  of  the  country  is  just  as 
great  as  in  a  city.  "  The  country  is  full  of  doctors ;  " 
every  little  town  has  ft-om  one  to  five  or  six,  and  they  are 
not  all  blockheads  [either,  but  wide-awake,  shrewd  men, 
who  understand  their  business.  Country  practice  is 
more  difficult  than  city  for  many  reasons.  The  country 
physician  is  known  by  all,  and  his  every  movement  is 
watched  and  scrutinized  and  criticised.  When  he  makes 
a  mistake,  or  a  supposed  mistake,  it  is  heralded  every- 
where, and  "  off  comes  his  head  "  often.  If  the  city  doc- 
tor loses  a  case,  it  is  not  known  a  square  off,  and  it  doesn't 
hurt  him.  A  city  doctor  can  get  along  with  less  knowU 
edge,  for  he  is  always  acquainted  with  men  eminent  in 
their  specialties,  and  he  can  consult  them.  In  the  coun- 
try the  doctor  has  to  practise  all  the  branches  of  medi- 
cine in  order  to  be  successfiil,  consequently  he  has  to 
study  hard,  as  well  as  work  hard,  to  succeed. 

The  country  doctor's  social  advantages  are  not  to  be 
compared  to  the  city  physician's.  The  latter  can  have 
anything  in  the  city  suited  to  his  tastes,  while  in  the 
country  it  is  long,  wearisome  journeys  and  irregular 
sleep  and  irregular  meals.  I  ask  what  can  be  more 
wearing  ?  If  anyone  thinks  the  country  doctor  has  the 
best  end  of  it,  he  is  very  much  mistaken.  They  are  the 
backbone  of  the  profession,  and  have  not  gone  to  the 
country  for  lack  of  knowledge,  but  on  account  of  an  idea 
that  they  can  start  with  less  money,  which  is  often  a  mis- 
take. S.  C.  DuMM,  M.D. 

Columbus,  O.  

"DEAD   TEETH    IN   THE   JAWS." 

To  THB  Editor  of  Thb  Mbdical  Rbcosd. 

Sir  :  The  report  of  the  cases  of  otologia  occurring  in  the 
aural  service  of  Samuel  Sexton,  M.D.,  on  page  374,  cur- 
rent volume,  entitled  "  Pain  in  the  Ears  due  to  Irritation 
in  the  Jaws,*'  while  it  may  serve  to  direct  the  attention 
of  physicians  to  make  a  closer  examination  of  the  teeth 
in  sill  cases  of  pain  in  the  ears,  yet  fails  to  establish  the 
fact  that  retention  of  dead  (pulpless)  teeth  in  the  jaws  is 
a  prolific  source  of  aural  troubles.     A  careful  examina- 


474 


THE   MEDIGAL  RECORD. 


[October  25,  1884, 


tion  of  that  report  fails  to  disclose  an  alarming  number 
of  dead  (pulpless)  teeth.  Case  I.  reports  :  "Lower  first 
and  second  molars  on  both  sides  mere  shells."  No  proof 
that  the  pulps  were  dead.  The  surgeon  who  advised 
extraction  of  the  four  (temporary)  molars  destroyed  the 
masticatory  apparatus  of  the  child  for  at  least  three  years, 
and  in  all  probability  caused  the  first  permanent  molars 
to  tip  forward,  so  that  the  crowns  of  each  will  be  almost 
useless  during  life  for  mastication  ;  and  in  addition  to  the 
above  produced  an  irregularity  of  the  bicuspids  (yet  to 
make  their  appearance)  which  will  probably  render  it 
necessary  that  one  on  each  side  should  be  extracted  in 
order  to  afford  space  for  the  remaining  teeth.  Case  II. 
"  Both  upper  wisdom-teeth  in  a  carious  state.  Both 
lower  wisdom-teeth  just  (cut  ?  )  erupted."  The  absurdity 
of  the  proposition  that  the  wearing  of  the  vulcanite  plate 
increased  the  irritation  in  the  left  ear  is  too  palpable  to 
need  comment.  Case  III.  No  proof  of  dead  (pulpless) 
teeth.  Case  IV.  No  proof  of  pulpless  teeth.  The  pain 
in  the  ears  in  the  preceding  cases  was  undoubtedly  due 
to  exposed  or  nearly  exposed  pulps,  which  any  dental 
surgeon  could  have  relieved,  and  at  the  same  time  saved 
the  teeth  alive.  Case  V.  No  proof  of  pulpless  teeth. 
The  advice  was  good.  Case  VI.  No  proof  of  pulpless 
teeth.  From  the  report  it  seems  that  an  unnecessary 
number  of  teeth  were  extracted  because  they  were  cari- 
ous !  Case  VII.  No  proof  of  pulpless  teeth.  Removal 
of  the  salivary  calculus  probably  all  that  was  necessary. 
Case  VIII.  No  proof  of  pulpless  teeth.  The  erupting 
wisdom-tooth  probable  cause  of  pain  in  the  ear. 

The  comments  of  the  surgeon  in  charge  are  exceedingly 
entertaining.  He  first  advises  the  extraction  of  a  vast 
number  of  carious  (not  dead)  teeth,  and  then  complains 
that  the  wearing  of  plates  (celluloid,  vulcanite,  etc.)  is 
"  an  evil  of  vast  proportions."  I  agree  with  him  in  the 
proposition  that  a  vast  deal  of  ill-advised  dentistry  is  done 
every  day,  but  this  evil  is  due  as  much  to  the  ignorance 
of  the  surgeon  and  physician  as  to  the  lack  of  judgment 
and  skill  on  the  part  of  the  dentist.  It  is  no  uncommon 
experience  of  dental  surgeons  to  find  otherwise  well-in- 
formed medical  men  deplorably  ignorant  when  speaking 
of  dental  anatomy  and  the  diseases  of  the  teeth. 

The  editorial  comments  on  the  report  above  reviewed 
are  not  particularly  well-timed.  The  idea  that  because 
an  alveolar  abscess  may  be  found  discharging  into  the 
mouth  a  drop  or  two  of  pus  every  day  should  be  thought 
a  sufficient  reason  for  the  extraction  of  the  tooth  is  not 
tenable,  as  it  is  well  known  that  any  alveolar  abscess — 
arising  from  death  of  the  pulp— can  be  cured  by  any 
competent  dental  surgeon.  I  agree  most  heartily  with 
the  editor  when  he  says,  "  It  would  seem  .  .  .  that 
perhaps  the  time  is  nigh  at  hand  when  medical  men 
should  be  themselves  better  informed  concerning  diseases 
of  the  mouth  and  jaws."  It  is  high  time.  No  intelli- 
gent dentist  could  be  such  an  ass  as  is  implied  in  the 
paragraph,  that  he  would  continue  *'  *  treating '  dead 
teeth  long  after  their  presence  in  the  jaws  has  given  rise 
to  alveolar  abscesses  and  neuralgias  more  or  less  pain- 
ful." The  necessity  for  "treating"  a  dead  (pulpless) 
tooth  is  not  well  established  until  the  formation  of  an 
alveolar  abscess.  It  is  presumed  that  no  argument  is 
called  for  to  sustain  the  proposition  that  alveolar  ab- 
scesses should  be  cured ;  that  nearly  exposed  pulps  in 
teeth  should  have  a  suitable  capping  interposed  between 
the  pulp  and  the  filling  to  prevent  thermal  shock ;  "  that 
all  dental  surgeons  should  receive  proper  and  sufficient 
medical  teaching  to  enable  them  to  prescribe  intelli- 
gently and  to  diagnose  correctly ; "  but  in  the  light  of 
present  advanced  dental  knowledge  and  practice,  to  have 
the  profession  of  dental  surgery,  whose  history  contains  a 
list  of  names  not  less  known  in  the  world  of  science  than 
those  of  any  other  honorable  profession — Owen,  Czermak, 
James,  Mayital,  Wells,  Harris,  Garrettson,  Wedl,  Bell, 
and  hosts  of  others  whose  names  are  indissolubly  con- 
nected with  the  science  and  practice  of  dentistry — al- 
luded to  as  **  individuals  whose  limited  knowledge  of 


medicine,"  etc.,  by  the  editor  of  an  enlightened,  progres- 
sive,  and   professedly  liberal  medical  journal,  is  rather 
straining  at  the  gnat  to  swallow  a  camel.     This  present 
"individual"  protests  against  such  editorials  as  undigni. 
fied,  unjust,  and  uncalled  for.  Respectfully  yours, 
A.  W.  Harlan,  M.D.,  D.D.S., 
Prof,  Dental  Surgery 
Coll,  Physicians  and  Surgeons  of  Chicago, 

70  Dbarborn  Strkkt,  Chicago. 


THE    FEEDING    OF    INFANTS    WITH    COWS' 
MILK. 

To  TUB  Editok  or  Thb  Mbdical  Rbcskd. 

Sir  :  The  Medical  Record  of  September  13th  con- 
tains an  article  by  Dr.  John  Binnie  upon  artificial  feed- 
ing of  infants  by  means  of  cows*  milk.  I  am  an  earnest 
advocate  of  this  article  as  a  substitute  for  mother's  milk, 
and  agree  in  the  main  with  the  suggestions  advanced  in 
the  author's  paper.  But  I  am  of  the  opinion  that  too 
much  stress  is  laid  upon  the  necessity  of  employing  milk 
from  one  and  the  same  cow.  If  the  article  is  good,  I 
maintain  that  its  effect  upon  the  infant  is  in  nowise  dele- 
terious, whether  it  be  procured  from  one  or  many  cow?. 
The  great  desideratum  is  that  it  be  as  pure  as  possible 
It  is  my  experience  that  change,  always  keeping  in  view 
the  purity  of  the  milk,  produces  no  harmful  results.  To 
exemplify  :  A  few  years  ago  I  had  under  daily  observa- 
tion an  infant  six  months  old,  travelling  with  its  parents 
through  the  various  large  cities  and  countries  of  Central 
Europe.  I  lay  special  stress  upon  citieSy  because  milk 
is  supposed  to  be  more  inferior  there  than  in  the  country. 
A  month  was  consumed  in  the  journey,  this  latter  being 
interrupted  by  rests  of  one  to  seven  days'  duration. 
Upon  arrival  at  these  places  the  best  milk  that  could  he 
procured  was  ordered,  and  notwithstanding  this  constant 
change  of  milk  obtained  from  different  cows  of  the  same 
nationality,  and  even  the  immediate  substitution  of  that 
of  another  State,  the  infant  enjoyed  most  perfect  health. 

I  coincide  with  Dr.  Binnie  in  respect  to  the  causes 
which  produce  harmful  effects,  with  the  exception  of  the 
one  cited  above.  Change  is  the  most  insignificant  of 
the  causes  of  failure. 

The  predominating  cause  of  evil  results  from  bottle- 
feeding  is  the  want  of  cleanliness.  Not  only  should  the 
utensils  be  perfectly  clean,  but  they  should  be  of  the 
simplest  possible  character.  All  feeding-bottles  with 
long  rubber  attachments  should  be  condemned.  ^Vhile 
these  lighten  the  labor  of  the  attendant,  they  are  a  con- 
stant menace  to  the  child's  health  inasmuch  as  they 
become  a  focus  of  disorders,  the  walls  of  the  tubes  afford- 
ing a  depot  for  the  particles  of  milk  ;  and  notwithstanding 
they  may  be  rinsed,  brushed  out,  and  allowed  to  remain 
in  water,  they  will  in  a  short  time  be  found  coated,  this 
coating  fermenting  the  milk  passing  through  them.  The 
simple  nipples,  then,  are  the  safest.  In  employing  these 
several  should  be  kept  on  hand,  that  those  not  in  use 
might  stand  always  in  cold  clean  water.  When  they  are 
found  to  be  coated,  they  should  be  discarded.  With 
respect  to  the  bottles,  it  is  better  to  have  also  several  of 
these,  those  not  in  use  being  filled  with  water,  They 
should  frequently  be  cleansed  with  soda  and  hot  water. 

Feeding  should  be  limited  to  every  two  hours  in  the 
very  young  child.  Later,  the  time  may  be  extended  to 
every  third  hour.  In  the  interval,  If  the  infant  cries,  I 
advise  a  little  pure  or  slightly  sweetened  water.  During 
the  early  months  the  proportion  of  milk  should  be  three 
parts  to  one  of  warm  water,  the  former  uncooked.  The 
amount  of  nourishment  must  be  gauged  to  the  little  one's 
capabilities  to  retain  it.  The  flask  should  be  removed 
from  the  child's  mouth  immediately  after  it  is  emptied, 
in  order  that  air  may  not  be  sucked  into  the  stomach. 
During  the  process  of  feeding  the  nipple  must  be  main- 
tained full  for  the  same  reason.  I  have  found  that  a 
teaspoonful  of  lime-water  added  to  each  bottle  of  milk  is 
indicated  when,  there  is  much  vomiting  after  feeding,  or 


October  25,  1884.] 


THE  MEDICAL  RECORD. 


475 


when  the  bowels  are  "  bad."  When  there  is  constipation, 
a  teaspoonful  of  mag.  sulph.  mixed  with  the  milk  is  called 
for.  In  preparing  this  it  is  better  to  add  the  milk  to  it 
slowly  in  a  vessel  other  than  the  bottle  until  the  powder 
is  entirely  dissolved,  when  it  is  poured  into  the  flask.  If 
it  is  not  so  treated  tlie  nipple  is  often  clogged  up. 

At  no  age  under  two  years  do  I  permit  table  food  to 
be  eaten.  I  confine  the  feeding  to  the  bottle,  crackers, 
and  bread  with  very  little  butter.  I  have  seen  children 
thus  fed  pass  over  the  entire  period  without  experiencing 
a  day's  sickness,  excepting  the  eruption  of  the  teeth  and 
vaccination.  I  have  never  known  them  to  suffer  even  with 
colia 

I  am  opposed  to  all  species  of  artificial  food  as  a  sub- 
stitute for  cows'  milk,  believing  that  the  latter  is  the 
nearest  approach^to  mother's  milk. 

In  conclusion,  I  would  say  that  when  the  mother  is 
from  any  cause  unable  or  unwilling  to  nurse  her  infant, 
I  unhesitatingly  elect  bottle-feeding,  giving  it  preference 
to  the  wet-nurse,  believing  as  I  do  that  the  child  will 
thrive  as  well,  and  will  run  fewer  risks  than  if  the  latter 
method  be  adopted.  A  child  fed  as  I  have  indicated  has 
every  chance  of  living,  and  will  develop  as  well  as  one 
fed  upon  its  mother's  milk  or  one  wet-nursed.  That  it 
demands  more  care  and  calls  for  more  attention  there  is 
no  question.  Bottle-feeding  should  be  intrusted  to  careful 
hands  only,  and  should  be  supervised  by  the  medical 
attendant.  Etisnns  C.  Vidal,  M.D, 


SHALL  ARMY  SURGEONS  PRACTISE  OUTSIDE 
THEIR  POSTS? 

To  THB  Editor  or  lbs  Mbz>ical  Rbcord.  . 

Sir  :  In  my  ^last  letter,  regarding  the  practice  of  army 
surgeons  among  civilians,  I  stated  that  Dr.  Stanton  rep- 
resented the  matter  in  an  unfair  light,  and  his  late  argu- 
ments do  not  alter  my  views.  It  seems  difficult  to 
onderstand  why  an  army  surgeon  should  not  have  a  per- 
fect right  to  practise  his  profession  among  civilians,  if 
they  choose  to  employ  him,  and  if  it  does  not  interfere 
with  the  duties  of  a  medical  officer. 

The  point  advanced  by  Dr.  Stanton,  that  the  law  offi- 
cers of  the  Government  are  not  allowed  to  give  legal  ad- 
vice to  the  public,  is  not  well  taken.  It  would  seriouslv 
interfere  with  the  proper  administration  of  justice  if 
judges  and  prosecuting  attorneys  were  allowed  to  engage 
in  private  practice,  but  no  ill  effects  can  arise  by  giving 
army  surgeons  the  privilege  of  extending  their  services 
to  civilians.  A  man  who  enters  the  military  or  civil 
service  of  the  Government  does  by  no  means  surrender 
the  rights  and  privileges  of  a  citizen,  and  no  reason  or 
justice  could  possibly  be  found  in  any  law,  regulation, 
or  order,  which  would  prevent  a  physician  in  the  employ 
of  the  Government  from  using  his  knowledge  and  skill, 
during  his  leisure  hours,  not  only  for  the  benefit  of  his 
fellow-men,  but  also  for  the  purpose  of  increasing  his 
income. 

In  other  branches  of  the  public  service,  either  muni- 
cipal. State  or  federal,  the  attaches  engage  in  outside 
work,  and  it  is  quite  common  to  see  Government  clerks 
augment  their  income  by  performing  clerical  work  for 
private  parties  during  their  leisure  time.  If  Dr.  Stan- 
ton's arguments  hold  good,  why  is  it  that  it  never  oc- 
curred to  our  lawyers,  or  other  professional  or  business 
men,  that  it  is  improper  for  Representatives  and  Senators 
to  give  legal  advice,  or  to  continue  the  practice  of  their 
profession,  or  attend  to  other  business,  while  they  occupy 
seats  [in  Congress  and  are  paid  a  fixed  salary  ?  Why 
docs  not  Dr.  Stanton  object  to  the  outside  practice  of 
physicians  and  surgeons  of  municipal  or  other  govern- 
ment hospitals,  medical  officers  of  boards  of  health, 
police  surgeons  and  harbor  physicians,  not  to  mention 
the  medical  officers  of  the  navy,  the  surgeons  of  the 
Marine  Hospital  service,  pension  surgeons,  and  many 
others  ?     Most  of  them  draw  fixed  salaries,   "  in   part 


paid  for  by  the  very  physicians  they  compete  with,"  and 
many  of  these  positions  are  as  permanent  as  those  held 
by  army  surgeons,  and  are  the  means  of  bringing  the 
holders  a  large  private  practice,  which  medical  officers 
of  the  army  can  never  hope  to  gain. 

As  Dr.  Stanton  says,  what  will  apply  to  one  branch  of 
the  public  service  must  apply  to  all  others.  According 
to  his  views  it  would  be  sound  logic  to  prevent  all  pub- 
lic office-holders  from  engaging  in  private  pursuits  during 
their  leisure  hours.  To  allow  them  to  occupy  their  spare 
time  for  any  laudable  and  honorable  purpose,  with  a  view 
of  adding  a  few  dollars  to  their  fixed  salaries,  would  open 
a  way  for  "  unfair  and  unjust  competition  "  with  others, 
who  have  not  "  an  assured  and  regular  income  outside  of 
their  practice,"  trade,  or  profession. 

I  still  claim  that  much  of  the  outside  work  of  army 
surgeons  is  done  with  a  view  of  increasing  their  knowl- 
edge, and  I  have  found,  as  a  general  rule,  that  citizens 
often  apply  to  army  surgeons  for  medical  advice,  for 
which  they  never  expect  to  pay,  because  they  seem  to 
be  impressed  with  Dr.  Stanton's  views,  "that  it  is  not 
proper  for  them  (the  surgeons)  to  receive  fees  for  so 
doing."  Much  of  the  work  of  military  surgeons  among 
civilians  is  a  work  of  charity,  and  citizens  in  need  of 
medical  aid  never  apply  in  vain  to  army  medical  officers 
for  assistance.  The  argument  that  it  would  be  ungra- 
cious to  prohibit  a  medical  officer  from  extending  relief 
to  civilians  is  by  no  means  "  umitigated  bosh,"  and  I  re- 
call more  than  one  case,  which  happened  not  only  on 
frontier  posts,  but  also  in  large  cities,  with  no  "  dearth  of 
local  physicians,"  where  such  restrictions  would  have 
been  followed  by  most  serious  results. 

But  it  is  also  true  that  at  a  few  military  posts  some  of 
the  better  class  of  people,  living  in  the  vicinity,  consult 
the  army  surgeon,  and,  like  all  decent  people,  pay  for  the 
services  rendered.  The  incomes  of  army  surgeons  are 
by  no  means  brilliant,  and  since  most  of  them  have  fam- 
ilies to  support  and  children  to  educate,  it  appears  only 
praiseworthy  if  they  try  to  increase  their  income  by  en- 
gaging in  private  practice. 

Medical  officers  of  the  army  are  not  very  liable,  as  a 
general  rule,  to  come  in  active  competition  with  local 
physicians.  At  the  majority  of  posts  their  official  duties 
occupy  most  of  their  time,  and  even  if  such  is  not  the 
case,  they  suffer  from  the  disadvantage  that  they  are  al- 
most strangers  in  the  vicinity  of  their  stations.  Army 
surgeons  are  usually  changed  every  few  years,  and  peo- 
ple are  not  in  the  habit  of  changing  their  old  and  tried 
physician,  if  he  is  what  he  should  be,  a  friend,  an  adviser, 
and  a  man  well  versed  in  the  art  of  healing. 

I  have  occupied  much  of  the  valuable  space  of  your 
paper,  but  I  shall  not  ask  your  indulgence  in  the  future, 
and  if  additional  replies  should  be  required,  I  beg  to 
transfer  the  matter  to  abler  hands. 

Very  respectfully,  Caduceus. 


Chloroform  a  Dangerous  Remedy  for  Tape- 
worm.— Dr.  J.  W.  Carhart,  of  Tampasas,  Tex.,  writes 
that  on  August  loth  he  administered  the  following  pre- 
scription for  tape-worm,  as  recommended  by  Dr.  J.  G. 
Brooks : 

3.  Chloroform, 

Ext.  filic  mas.  fl &&  3  ij. 

Emul.  ol.  ricini ^i^^U 

M.  Sig. — One  dose  after  twenty-four  hours'  fast. 

The  patient,  a  lady,  very  soon  after  taking  the  dose, 
passed  through  the  excitement  stage  of  anaesthesia,  then 
suffered  from  nausea  and  vomiting.  She  did  not  get 
over  the  bad  symptoms  until  next  day.  No  tape-worm 
was  discharged,  though  the  patient  had  been  passing 
fragments  for  some  time.  Dr.  Carhart  has  had  good  re- 
sults with  Tanret'e  pelletierine,  and  is  done  with  chloro- 
form. 


476 


THE   MEDICAL  RECORD. 


[October  25^  1884. 


^vmvi  and  ^^wg  ^evos. 

Official  List  of  Changes  in  the  Stations  and  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army, 
from  October  12  to  October  18,  1884. 

NoRRis,  Basil,  Lieutenant  -  Colonel  and  Surgeon. 
Relieved  from  duty  as  Attendant  Surgeon,  Washington, 
D.  C,  and  ordered  for  duty  as  Medical  Director  Divi- 
sion of  the  Pacific  and  Department  of  California,  reliev- 
ing Surgeon  £.  I.  Baily.  Colonel  Baily,  on  being  re- 
lieved, will  assume  the  duties  of  Attendant  Surgeon  at 
San  Francisco,  Cal. 

Spencer,  William  C,  Major  and  Surgeon.  From 
Department  of  Dakota  to  Department  of  the  East 

GoDDARD,  Charles  £.,  Major  and  Surgeon.  To  be 
relieved  from  duty  at  Jefferson  Barracks,  Mo.,  and  to  re- 
port for  duty  in  Department  of  Dakota. 

McClellan,  Ely,  Major  and  Surgeon.  From  De- 
partment of  the  East  to  duty  at  Cavalry  Depot,  Jefferson 
Barracks,  Mo.     S.  O.  242,  A.  G.  O.,  October  15,  1884. 

McKee,  James  C,  Major  and  Surgeon.  Granted 
leave  of  absence  for  one  month,  with  permission  to  apply 
at  Division  Headquarters  for  one  month's  extension. 
S.  O.  149,  par.  I,  Department  of  Colorado,  October  3, 
1884. 

Wolverton,  W.  D.,  Major  and  Surgeon.  Granted 
one  month's  leave  of  absence,  to  take  effect  .when  his 
services  can  be  spared  by  his  Post  Commander.  S.  O. 
211,  par.  4,  Department  of  the  East,  October  16,  1884. 

Havard,  Valery,  Captain  and  Assistant  Surgeon. 
Assigned  to  temporary  duty  at  Fort  Schuyler,  New  York 
Harbor,  N.  Y.  S.  O.  211,  par.  2,  Department  of  the 
East,  October  16,  1884. 

Porter,  J.  Y.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month,  on  surgeon's 
certificate  of  disability,  with  permission  to  leave  tlie  limits 
of  the  department.  S.  O.  138,  par.  3,  Headquarters  De- 
partment of  Texas,  October  9,  1884.  Confirms  tele- 
graphic order  of  same  date. 


Official  List  of  Chaises  in  the  Medical  Corps  of  the  U.  S. 
Navyy  during  the  week  ending  October  iZ,  1884. 

Brush,  Geo.  R.,  Surgeon.  To  temporary  duty  at 
the  Naval  Laboratory.     October  11,  1884. 

BuRBANK,  Chas.  H.,  Medical  Inspector.  Detached 
from  the  Brooklyn,  and  placed  on  waiting  orders.  Octo- 
ber 15,  1884. 

Clark,  John  H.,  Surgeon.  Detached  from  the 
Lackawanna,  and  detailed  as  Fleet  Surgeon  of  the  Pa- 
cific Station.     October  1 7,  1884. 

CoofCE,  George  H.,  Surgeon.  To  the  Lackawanna. 
October  17,  1884. 

Edgar,  John  M.,  Passed  Assistant  Surgeon.  To  the 
receiving  ship  Franklin.     October  11,  1884. 

Hudson,  A.,  Medical  Inspector.  Detached  from  the 
Lancaster,  and  placed  on  waiting  orders.  October  14, 
1884. 

HuGG,  Joseph,  Surgeon.  Placed  on  waiting  orders. 
October  13,  1884. 

L0V.ERING,  P.  A.,  Passed  Assistant  Surgeon.  De- 
tached from  the  Lackawanna,  and  placed  on  waiting  or- 
ders.    October  17,  1884. 

Marsteller,  E.  H.,  Passed  Assistant  Surgeon.  De- 
tached from  the  Monongahela,  and  ordered  to  the 
Lackawanna.     October  17,  1884. 

Martin,  William,  Assistant  Surgeon.  Detached 
from  the  Passaic,  and  placed  on  waiting  orders.  Octo- 
ber 14,  1884. 

Martin,  H.  M.,  Passed  Assistant  Surgeon.  Detached 
from  the  Brooklyn,  and  placed  on  waiting  orders. 


ppCcdical  StjeniB* 


Contagious  Diseases — Weekly  Statement.— Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
die  week  ending  October  18,  1884 : 


Week  Ending 


Cotes, 
October  11, 1884 
October  18,  1884 

Deaths* 
October  11,  1884 
October  18,  1884 


ii 


I 


Electricity  as  an  Agent  in  Promoting  the  Ab- 
sorption OF  Pleuritic  Effusion. — Dr.  W.  T.  Baird, 
of  Albany,  Texas,  writes  us  a  letter  commenting  upon 
Dr.  Guiseppe  Manzini's  views  on  the  use  of  electricity 
in  pleuritic  effusions.  Dr.  Baird  thinks  that  electricity 
is  not  necessarily  an  irritant,  but  may  act  as  a  powerful 
sedative,  and  it  is  not  therefore  contra-indicated  in  the 
inflammatory  stage  of  pleurisy.  He  argues  also  that  it 
is  not  by  electrization  and  stimulation  of  the  respiratory 
muscles  that  electricity  causes  absorption,  but  by  its 
vaso-motor  stimulation  and  general  tonic  effects.  Gen- 
eral as  well  as  local  faradization  would  be  a  more  suc- 
cessful method  in  treating  these  effusions. 

The  Motor  Power  of  the  Human  Body.— Dr. 
Marey,  of  Paris,  read  a  paper  on  this  subject  at  the  In- 
ternational Congress  of  Hygiene,  in  which  he  described 
the  ingenious  manner  in  which  he  had  succeeded  in 
measuring  the  motive  power  of  the  human  body  in  its 
every  movement.  Planks,  with  india-rubber  coils  under- 
neath, recorded,  by  expelling  the  air  they  contained,  the 
exact  pressure  of  the  foot.  The  motions  were  measured; 
and  photographs,  taken  in  one-thousandth  of  a  second, 
recorded  every  attitude  during  a  leap,  and  where  and 
when  the  effort  was  greatest  By  such  studies,  M.  Marcy 
had  been  able  to  prove  that  something  was  gained  in 
the  power  of  walking,  in  quickening  the  step  from  forty 
to  seventy-five  steps  per  minute.  But  the  latter  figure 
was  the  extreme  limit ;  with  a  greater  number  of  steps 
power  would  only  be  lost  instead  of  gained. 

The  Experiences  of  a   Hay-fever   Patient.— A 
writer  in  the  Times  says :  **  I  have  had  *  hay-fever '  for 
nearly  twenty  years,  and  I  have   visited  many  of  the 
places  set  down  in  the  association  pamphlet  as  exempt 
The  best  locality  I  have  so  far  found  is  the  Adirondack 
Mountains.     At  Keene  Valley,  X,ake  Placid,  and  a  hun- 
dred other  places  within  them,  there  is  sure  relief.    But 
one  must  be  sure  to  go  into  the  mountains  away  from 
the  railroad.     I  have  tried  the  White  Mountains  for  four 
years.     They  are  excellent,  but  not  always  thoroughly 
exempt,  for  sin  overheating  of  the  body  will  often  bring 
on  a  bad  attack  of  sneezing,  and  in  rainy  weather  one 
notices  a  slight  difficulty  in  breathing.     In  the  Adiron- 
dacks  there  are  places  so  exempt  that  one  can  do  any- 
thing and  not  know  that  he  ever  had  *hay  fever.'    I 
have  tried  many  of  the  places  mentioned  on  Lake  Supe- 
rior, and  have  found  exemption  in  them  all.     Neither 
have  I  suffered  in  St.  Paul  or  Minneapolis  to  any  no- 
ticeable extent,  or  at  Lake  Minnetonka.     Fire  Island, 
the  Isles  of  Shoals,  and  others  similarly  situated  near  the 
land,  are  not  so  good  as  the  primitive  mountains.    They 
relieve  the  disease  wonderfully  at  all  times,  but  it  is  only 
when  the  wind  blows  from  the  sea  that  they  give  perfect 
exemption." 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  a6,  No.  i8 


New  York,  November  i,  1884 


Whole  No.  730 


(^KiQixmX  |i.rtijcljea. 


CONTRIBUTIONS  TO 

THE  ANATOMY  OF  THE  LEMNISCUS. 

WtTH  Remarks  on  Centripetal  Conducting  Tracts 
IN  the  Brain, 
By  E.  C.  SPITZKA,  M.D., 
PKonssoK  or  nsumo-anatomy  and  physiology  in  the  nkw  yokk  fost-gkao- 

UATB  MBDICAL  SCHOOL. 

(Continued  from  page  451.) 

IV. 

V. — Relations  of  the  Lemniscus  Proper  to  the  In- 
ternal Capsule. 
Without  entering  into  a  special  discussion  of  that  part 
of  the  lemniscus  which  occupies  the  olivary  territory  in 
lower  levels,  and  in  higher  ones  becomes  fused  with  that 
portion  of  the  interolivary  tract  which  with  it  constitutes 
the  main  part  of  the  lemniscus,  let  us  proceed  to  consider 
its  relations  in  higher  (cephalic)  levels,  where  the  greatest 
obscurity  prevails. 

The  gross  appearances  indicate  a  transition  of  a  part 
of  the  lemniscus,  which  reaches  higher  (more  cephalic) 
levels  than  the  post-optic  lobes,  into  the  internal  capsule. 
To  what  extent  there  i§  interruption  by  thalamic  gray 
matter  is  uncertain,  but  the  gross  appearances  alluded  to 
appear  to  correctly  match  the  real  relations. 

In  levels  slightly  caudad  of  the  one  in  the  figure,  where 


Mesencephalic  Region  of  Man. 
_eniina;    6,  field  of  cptic  radiado 
it  is  traversed  and  perhaps  joined  (?)  by  thalamic  radiations  ;  7,  18, 


93,  numbers  m  aqueduct, 
tic  radiations  of  Gratiolet,   chiefly  dc- 


10,  pas- 
throug 


Pig.  16. — Transirerse  Section  through   lliatamic  and  Anterior 
pointers  on  nuclei  of  third  pair  ;  3,  anterior  pair  of  corpora  quadrigemina 

nved  from  extemai  geniculate  body  and  optic  tract;  it  is  traversed  and  p         ^   ,  .,    ,  ..  ,.  . 

sageof  Gzatiolet's  fasciculus  into  the  capsule,  in  part  to  temporal  lobe  :  20,  21,  21,  similar  passage  of  pes  fibres  into  and  through 
the  posterior  serrations  of  the  lenticular  nucleus  (21) ;  12,  pes  :  13,  substantia  nigra ;  i^,  tegmental  nucleus  ;  15,  roots  of  third  paur. 
It  was  n^lected  to  designate  the  lemniscus  field  ;  comparison  with  Fi^.  14,  L,  will  aid  in  its  identification  :  it  occupies  the  triangular 
field  inchided  between  the  upper  lateral  angle  of  the  aqueduct  gray,  intrudes  one  end  between  the  outer  aspect  of  the  tegmental 
nncieus  and  the  substantia  nigra,  and  detaches  its  third  comer  part  toward  the  field  6 ;  the  mesai  demarcation  is  not  as  distinct  in 
this  level  as  in  one  of  those  to  be  described. 

the  thalamus  is  struck  in  its  free  portion,  a  clear  triangu- 
lar field  is  seen  (6),  which  is  an  inverted  and  magnified 
reproduction  of  the  lemniscus  triangle ;  it  is  a  fasciculus 
of  the  corona  radiata.  On  passing  cephalad,  a  part  of 
the  lemniscus  runs  into  a  field  occupying  the  place  of  6. 
It  would  appear  as  if  tfie  thalamus  intruded  its  substance, 
so  that  to  reach  its  double  the  lemniscus  has  to  break 
through.     The  more  plausible  explanation  seems  to  be 


that  the  fasciculus  bends  round  from  within  outward, 
with  the  convexity  cephalo-mesad,  leaving  the  gray  streak 
latero-caudad,  so  that  what  was  internal  and  posterior 
(meso-caudal)  in  the  lemniscus,  became  external  and  an- 
terior (ecto-cephalic)  in  the  capsule,  and  what  was  ex- 
ternal m  the  lemniscus  became  internal  in  the  field  re- 
placing 6.  The  curve  in  field  27  of  Fig.  12  indicates 
such  a  relation,  while  the  course  of  the  tract  in  the  speci- 
men from  which  Fig.  11  was  drawn,  is  of  similar  import, 
but  indicates  also  a  laminated  dispersion  through  gray 
matter. 

Forel  *  could  never  discover  a  transition  of  lemniscus 
fibres  into  the  thalamus,  a  small  part  he  traces  to  the 
corpus  mammillare,  but  the  major  part  {Haupt-iheU)  be- 
comes lost  in  a  confused  medley  of  finely  broken  up 
gray  and  white  substance  in  the  latitude  of  Meynerfs 
bundle  in  the  dog,  while  in  man  the  gray  substance  is 
wanting,  the  lemniscus  remains  more  compact,  and  as  I 
have  not  been  able  to  confirm  from  a  study  of  specimens 
stained  in  fuchsin,*  its  fibres  appear  matted  together 
like  felt- work.*  I  am  unable  to  come  to  any  conclusion 
as  to  the  relation  between  the  post-brachium  and  the 
lemniscus  layer  alleged  by  Forel.  The  direction  of  his 
sections  is  about  the  most  unfortunate  to  have  selected, 
as  the  majority  of  tracts  are  divided  obliquely  in  them. 
His  employment  of  transverse  sections  (Meynert-Stilling's 
plane)  in  the  dog,  possibly  accounts  for  his  finding  the 
relations  of  many  tracts  clearer  in  that  animal  than  in 
man.  Our  conceptions  as  to  direction  and  space  in  anat- 
omy are   commonly  associated  with    the    great   body 

planes,  and  to  this  sim- 
ple tradition  of  topog- 
raphy Forel's  sections 
do  great  violence, 

I  think  that  by  describ- 
ing the  relations  of  the 
lemniscus  main  portion 
{Haupt'tkeil—FoTci)  in 
three  successive  levels 
of  the  Meynert-Stilling 
plane,  I  may  make  my- 
self better  understood 
than  by  proceeding  im- 
mediately to  consider 
the  course  of  the  fascic- 
ulus as  such. 

First  level:  Through 
the  anteriormost  twelfth 
of  the  pons,  and  the  mid- 
dle of  the    post-optic 
lobes  (post  pair,  C  //, 
quadrigemina),  the  main 
lemniscus  and  the  de- 
tachment to  the  post- 
optic    lobes    are   alto- 
gether, the  pedo-lemnis- 
cal  fasciculus    nearly 
continuous,*  covering 
Soemmering's  substance  dorsally.     The  mesal  two-fifths 
of  this  united  area  follows   the  ventral  face  of  Weme- 
kinck's  commissure,   being  separated  from  it  by  a  gray 


1  Archiv  fiir  Psychiatrie,  vii.,  pp 
*  I  am  indebted  to  Dr.  Starr  f 


this  stainmg  reagent ;  its  future  aiefnlness 


think  will  be  made  most  evident  in  this  particular  region.  ^        .      i-v 

s  Fibzes  can  be  traced  for  more  than  the  width  of  the  field  outward  :  other  fibre 

noticed  obliquely  divided  in  the  interstices  of  the  intervening  bundles  cannot  b 

confounded  with  them. 
*  A  small  detachment  of  Soemmering*!  substance  mtervenes. 


478 


THE  MEDICAL  RECORD. 


[November  i,  1884, 


intercalation.  In  my  case  of  secondary  degeneration 
the  outer  portion  was  shrunken  and  degenerated,  only  a 
small  area  of  the  part,  a  third  the  half  diameter  from  the 
raphe,  escaping.' 

Second  level :  Through  the  anterior  pair,  and  the  pedun- 
culi  cerebri,  at  the  level  below  the  emergence  of  the  third 
pair,  striking  at  the  same  time  the  external  geniculata. 
Main  lemniscus,  separated  through  substantia  j,  nigra  from 
the  pedo-lemniscal  tract  by  a  large  interval.  It  occupies 
a  nearly  mortar-shaped  area,  the  mortar  being  supposed 
to  be  inclined  dorso-laterad.  Its  base  rests  half  on  the  lat- 
eral sector  of  the  area  of  the  tegmenta  brachium^  the 
other  half  fades  away  into  the  dorso-mesal  face  of  the 
lateral  half  of  the  substancia  nigra.  The  mesal  end  of 
the  top  of  the  mortar  is  represented  by  the  end  of  the 
lemniscus  field,  the  ectal  end  by  fibres  which  begin  to 
field  through  the  gray  matter  between  the  lemniscus  and 
pulvinar.  Most  of  these  fasciculi  may  be  traced  a  consider- 
able distance  toward  the  field  which  replaces  6  of  Fig. 
16  in  higher  levels.  In  lower  levels  where  this  fielding 
off  detachment  is  not  marked,  the  lemniscus  resembles 
the  horns  of  a  Cape  buffalo,  attached  to  the  field  of  the 
tegmenta  brachium^  just  as  the  latter  are  attached  to  the 
bulbous  enlargements  of  the  Cape  buffalo's  forehead.' 
Degeneration  in  my  case  occupied  the  ectal  half  of  the 
mortar  as  well  as  the  process  directed  toward  the  sub- 
stantia nigra.  The  part  directed  to  the  tegmental  nu- 
cleus, and  which  is  mixed  with  fibres  of  the  tegmentum 
proper  was  unaffected. 

Third  level:  The  lemniscus  area  described  under  two 
becomes  smaller  and  smaller  as  the  fielding  off  continues ; 
finally  direct  £aisciculi  can  be  traced  into  the  internal 
capsule.  These  were  degenerated  in  my  case,  where 
detailed  examination  showed  total  destruction  of  the  mid- 
dle (main)  part  of  the  lemniscus  tract  The  course  of 
the  bundle  which  the  dying  out  lemniscus  sends  to  the 
capsule,  is  first  directly  ectad,  and  into  the  lower  part  of 
the  field  continuous  with  6 ;  it  does  not  join  the  latter, 
but  changing  in  direction  dorsad  leaves  the  level  of  the 
section.  The  field  which  these  lemniscus  fibres  appear 
to  occupy  in  the  capsule  is  situated  on  the  border  of  the 
inward  and  downward  slope  of  the  thalamus,  in  a  level 
slightly  anterior  to  that  of  figure  16 ;  to  accommodate  it, 
the  triangular  field  6,  is  moved  laterad  and  more  dorsad. 
A  direct  continuity  to  this  field  is  not  demonstrable,  but 
as  it  appears  with  the  disappearance  of  the  lemniscus 
the  course  of  the  fibres  is  in  that  direction,  and  no  other 
adequate  source '  can  be  discovered,  it  is  reasonable  to 
connect  them,  provisionally  at  least  As  already  stated, 
fibres  can  be  traced  from  the  lemniscus  field  to  the  bor- 
ders of  this  one,  and  above  this  level  the  corresponding 
part  of  the  lemniscus  can  no  longer  be  identified.  De- 
fibrillation supports  this  view  with  all  the  weight  which 
may  be  attributed  to  its  uncertain  evidence,  and  indicates 
that  the  fasciculus  in  which  it  runs  occupies  the  course 
represented  in  the  tract  27  of  Fig.  12.  In  my  case  of 
secondary  degeneration,  the  latter  occupied  a  field  dorsad 
of  the  radiations  from  the  tegmental  nucleus  to  the  cap- 
sule, and  up  to  date  has  not  been  traced  further. 

The  relations  of  the  internal  capsule  at  this  point  are 
very  complex,  but  interesting.  The  outermost  fibres  of 
the  pes  are  the  first  of  this  bundle  to  enter  it,  as  we  pass 
caudo-cephalad.  In  transverse  sections  a  bundle  is 
seen  (18,  Fig.  16),  which  is  repeated  in  a  number  of 
levels.  In  the  lowest  it  represents  Gratiolet's  fasciculus/ 
which  unites  the  occipito-temporal  lobe  to  the  cerebellum ; 
on  the  level  of  the  body  of  Luys,  the  corresponding  bun- 
dle connects  the  body  of  Luys  with  the  inner  articuli  of 

'  1  The  lemnisoo-pedal  tract  was  entirely  healthy.  On  the  normal  side  a  bundle  in 
the  plane  of  the  section,  ran  in  the  substantia  nigra  from  the  lemnisco-pedal  re^on 
to  die  outer  fifth  of  the  main  lemniscus,  joining  it  by  intrusion  and  densdculation. 

*  This  simiU  may  be  made  for  other  systems  in  the  mesencephalon,  there  are 
direc  concentric  repetitions  of  a  similar  arrangement,  one  of  these  being  the  posL 
long.  £uc.  of  the  t^gmoitum. 

*  The  post-brachium  is  not  extensive  enough  to  account  for  the  formation  of  this 
field,  lit  *s  ForePs  siatement  suggests,  the  two  be  confounded. 

*  Even  in  sections  the  suporficud  eraminer  is  misled  into  suspecting  a  rdaiioii 
to  the  optic  tract ;  hence  Stilling  the  younger  may  have  erred  in  descnbing  such  a 
connection,  as  he  discovered  it  by  the  faulty  defibriUadoo  method. 


the  lenticular  nucleus.'  This  latter  connection  is  one  of 
the  most  satisfactory  demonstrations  of  the  section 
method.  It  is  in  the  field  19,  which  with  the  elimination 
of  the  field  6  comes  in  contact  with  the  zonal  stratum  of 
the  thalamus,  that  the  outer  part  of  the  main  lemniscus 
tract  appears  to  run. 

I  am  unable  to  contribute  anything  to  the  knowledge 
of  that  part  of  the  lemniscus  which  iRechsig  traces  to  the 
ansa  lenticularis^  the  analysis  of  the  material  at  my  dis- 
posal  not  having  been  completed.  It  would  be  a  re 
markable  coincidence  if,  as  is  not  unlikely,  the  lemnisco* 
pedal  tract,  after  temporary  deflection  to  the  pes  pedun- 
culi,  took  the  same  course.  Thus  would  the  two  divisions 
of  the  stratum  intermedium  become  reunited. 

VI. — A  Note  Regarding  the  Column  of  Golu 

On  reviewing  the  subject  of  the  foetal  and  post-foetal 
development  of  nerve-tracts,  I  found  that  many  of  the 
corrections  since  made  of  Flechsig's  representation  of 
the  course  of  Goll's  columns,  in  his  first  treatise,  where 
he  leaves  them  undesignated  in  lower  dorsal  levels,  and 
represents  them  as  a  semi-oval  area  on  either  side  of  the 
posterior  fissure  of  the  cord,  could  have  been  made  by  a 
more  extensive  study  of  embryonic  material.    There  is 
really  no  difficulty  in  recognizing  this  tract,  in  perfectly 
firesh  cords.      Through  the  courtesy  of  Dr.   Jean  F. 
Chauveau,  I  had  the  opportunity  of  examining  the  cord 
of  a  foetus  (forty-one  centimetres  from  vertex  to  heel), 
and  found  that  the  tract  of  GoU  is  triangular  with  a 
pointed  apex,  directed  toward  the  point  of  entry  of  the 
posterior  roots ;  it  failed  to  reach  the  dorsal  periphery  of 
the  cord,  except  near  the  fissure.    It  exactly  reproduced 
the  extent  of  secondary  degeneration  noted  by  recent 
German  writers,  and  the  me^  degeneration  in  a  case  of 
locomotor  ataxia  in  a  patient  of  Dr.  McBride's^  in  whom 
the  root  zones  of  the  lumbar  enlargement  and  lower  dor- 
sal regions  alone  were  involved,  the  secondary  change  in 
the  columns  of  Goll  having  evidtsntly  advanced  only  up 
their  lower  (caudal)  portions.     In  the  foetus  above  re- 
ferred to  the  right  crossed  pyramid  tract  was  present  in 
the  lumbar  cord  in  its  lower  levels,  while  the  left  was  ab- 
sent.    Correspondingly  the  right  tract  extended  farther 
forward  on  the  right  side  in  the  cervical  region,  sending 
a  spur  between  the  two  divisions  of  the  anterior  part  of 
the  lateral  column.     Evidently  this  is  in  connection  with 
dextral  preference,  for  there  was  no  compensatory  de- 
velopment of  the  uncrossed  tract. 

Although  the  columns  of  Goll  were  still  ^ay  in  this 
foetus,  the  stratum  interolivare  was  in  part  distinctly  white, 
there  was  a  whitish  field  dorsad  of  the  ideal  prolonga- 
tion laterally  of  the  substantia  nigra,  and  this  field  ex- 
tended into  the  internal  articuli  of  the  lenticular  nucleus. 
I  am  becoming  more  and  more  convinced  from  the  con^ 
tradictory  nature  of  these  findings  that  absolute  reliance 
cannot  be  placed  upon  the  apparent  continuity  of  mye- 
linic development  In  this  case,  carefiil  analysis  showed 
that  the  white  matter  in  the  lenticular  nucleus  was  de- 
rived from  a  belt  of  white  fibres  surrounding  the  body  of 
Luys.  The  converse  of  Flechsig's  proposition,  that  nerve- 
tracts  which  do  not  develop  in  chronological  accord  do 
not  appertain  to  the  same  system,  has  already  been  shown 
to  be  erroneous  by  Forel. 

VII. — ^The  Relations  of  the   Sensory  Tracts  and 
THE  Trigeminus  Roots. 

The  cases  of  lesion  of  the  pons  and  oblongata,  whOe 
indicating  that  below  the  exit  of  the  trigeminus  nerve  the 
anaesthesia  of  the  face  is  on  the  side  of  the  lesion,  which 
was  the  case  in  a  tumor  of  the  pons  (caudal  half)  and 
oblongata,  last  autopsied  by  myself,  are  too  few,  and  in- 
volve too  many  other  factors  to  permit  of  the  unreserved 
acceptation  of  Starr's  conclusion  (/t?r.  «V.,  page  55)  :  that 
a  lesion  in  the  cephalic  part  of  the  trigeminal  area  in  the 
pons  will  always  cause  contra-lateral  anaesthesia,  as  stated 


1 1  haye  fiwnd  four  lenticular  mrtkuii  i 
fifth  cUstiiicdIy  marked. 


I  three,  and  in  ooa  ceee  t 


November  i,  i884,] 


THE  MEDICAL  RECORD. 


479 


by  him.  A  lesion  might  indeed  occur  in  this  part  of  the 
pons,  involving  the  trigeminus  roots---descending  of  the 
same  level,  or  ascending — previous  to  their  escape  from 
the  brain  axis,  or  their  union  in  the  great  sensory  root, 
and  naturally  would  result  in  anaesthesia  of  the  same  side 
throogbout  if  direct  descending  roots  existed. 

That  there  is  a  decussation  for  certain  of  the  roots  of 
the  sensory  division  of  the  trigeminus,  has  been  a  familiar 
fact  since  Meynert*s  day.     Of  this  nature  is  probably  the 
great  raphe  root  (Fig.  15,   5r),  and  a  beautiful  set  of 
fasciculi,' which  decussate  in  the  gray  matter  of  the  ponto- 
cnual  region  of  the  dog,  in  the  immediate  continuation 
cephalad  of  Wemekinck's  commissure  (x  of  the  tegmenta 
brachium).     These  fasciculi  run  from  a  field  which  cor- 
responds to  14  of  Fig.   10  i(not  necessarily  connected 
with  it),  decussate  in  the  gray  matter  to  the  opposite  side, 
where  in  a  beautiful  sweep  they  reach  the  exit  level  of 
the  fifth  pair.   It,  with  the  raphe  root,  embodies  probably 
the  decussated  connection  of  the  trigeminus   with  the 
higher  centres  which  Starr  had  in  mind.     If  the  latter's 
theorem  is  correctly  understood  by  the  writer,  it  implies 
that  the  area  of  the  cephalic  part  of  the  pons,  homologous 
with  the  root  region  of  the  caudal  half-— for  that  lies  in 
the  outer  third  of  the   reticular   formation— -contains  a 
centripetal  tract  derived  from  the  opposite  trigeminus 
nerve.     For  this  theorem  there  is  thus  far  no  anatomical 
support,  and  not  even  a  hypothetical  tract,  while,  as 
stated,  the  cases  cited  are  too  few  and  indecisive,  al- 
though the  general  proposition  that  somewhere  between 
the  capsule  and  the  nerve-root  a  decussation  must  take 
place  is  well  based  on  clinical  grounds,  and  has  not  been 
contradicted  since  Wernicke  first  asserted  it    The  raphe 
root  of  Meynert,  and  the  strands  discovered  by  me  in  the 
dog  and  ape,  cannot  be  traced  to  the  capsule,  and  it  is  a 
great  question  when  the  further  course  of  these  bundles 
will  be  determined,  as  small  focal  lesions  of  the  involved 
districts  are  among  the  rarest  occurrences  in  cerebral 
pathology.^ 

It  is  nowhere  explicitly  stated  by  Starr  that  he  con* 
sidered   the   descending    (mesencephalic)   root  of    the 
trigeminus  in  this  theorem,  although  he  speaks  of  its 
junction  with  the  ascending  root  as  the  spot  which  sepa- 
rates the  area  of  homo-lateral  and  contra-lateral  facial 
hemianaesthesia.     If  he  considered  the  root,  ordinarily  so 
called  a  sensory  root,  he  would — ^as  it  remains  on  the 
same  side  throughout,  from  its  origin  in  the  vesiculac 
cells — have  to  except  so  much  of  the  trigeminal  distribu- 
tion as  is  provided  for  by  that  nerve-root     Forel,  and 
Wernicke  agrees  with  him,  traces  this  root  into  the  motor 
division  of  the  tri^^eminus,  so  that  if  his  view  is  accepted, 
the  above  exception  need  not  be  made.     Wernicke  also 
traces  a  decussated  origin  from  the  substantia  ferruginea 
(locus  coeruleus),  which  receives  a  contribution  from  the 
raphe  root,  and,  after  decussation,  corresponds  to  what 
I  term  the  raphe  root     To  affect  this  tract,  the  lesion 
would  have   to  be  nearer  the  lateral  ventricular  angle 
than  Starr  indicates,  inasmuch  as  the  outer  third  of  Sie 
reticular  field  does  not  include  this  tract' 

Wernicke  calls  attention  to  the  dilemma  that  either 
the  descending  decussated  root  embodies  all  tactile  and 
pain  tracts  of  the  trigeminus,  or  that  some  other  undif- 
ferentiated part  of  the  area  destroyed  by  the  tumor  was 
in  connection  with  the  lower  root  I  believe  only  the 
latter  alternative  can  be  seriously  considered,  and  Starr's 
^planation  is  in  this  direction,  though  it  fails  to  accom- 
modate itself  to  all  the  facts  of  the  case,  besides  having 
as  yet  but  a  very  problematical  anatomical  basis.  He 
concludes,  namely,  that  the  central  tract  for  the  trigemi- 
nus runs  in  the  outer  part  of  the  tegmentum.     It  may  in 


>  I  observed  in  1877  an  oval  hemorrhage,  destroying  the  raphe  above  the  level 
of  the  raphe  root,  in  a  paretic  dement,  at  the  same  time  there  was  an  enormous 
leatriciilar  faemoniiage  and  a  meningeal  extravasation,  destroying  any  value  the 
case  mi^it  odierwise  have  had. 

*  Wernicke  amiounoed  the  separation  of  the  tri^^eminus  sensory  and  the  extremity 
■cMory  tracts  (p.  537,  Archiv  f.  Psyehiatrie,  viL)  seven  years  before,  and  also 
stated  that  sesuory  tracts  for  the  latter  remained  on  the  same  side  for  a  further 
He  also  considers  all  possible  en»lanations  and  objectioBS  to  them  that 
'tfa  the  symptoms  reported,  in  die  admirable 


part ;  but  the  only  cases  which  permit  of  a  conclusion,  as 
far  as  they  go,  antagonize  this  view.  Both  cases  are  cited 
by  Wernicke.  First,*  hemorrhage  in  the  iifwer  part  of 
the  left  cms  :  right  facial  and  extremity  hemianaesthesia, 
left  oculo-motor  paralysis,  right  facial  and  extremity  pa- 
ralysis. Second,'  pea-sized  cyst  in  inner  part  of  left  eras, 
enclosing  the  third  nerve  of  that  side  and  extending  to 
the  lamina  perforata  posterior :  left  oculo-motor  paralysis ; 
right  facial,  hypoglossal,  and  extremity  paralysis ;  right-, 
sided  diminution  of  sensibility^  including  the  face.  With 
connected  *^ serous"  softening  of  the  contiguous  right 
eras,  right  oculo-motor  paralysis  supervened  later.  From 
these  cases  it  is  to  be  inferred  that  the  trigeminus  and 
extremity  sensory  tract  travel  in  that  region  of  the  eras 
which  is  traversed  by  the  oculo-motor  nerve — in  fact,  the 
tracts  which  ran  in  the  inner  (and  outer)  confines  of  the 
tegmental  nucleus,  corresponding  thus  to  the  course  of 
the  decussated  fasciculi  found  by  me  [in  the  [dog,  to  v. 
Monakow's  Kinden-schleife,  and  to  Wernicke's  lemnisco- 
pedal  bundle.  As  the  anaesthesia  in  none  of  these  cases 
was  complete,  we  must  conclude  that  there  may  be  other 
tracts,  and  these  may  ran  as  Starr  indicates,  but  evi- 
dence does  not  point  exclusively  in  that  direction. 

VIII.— Conclusions  and  Some   General  Observa- 
tions. 

The  lemniscus  layer  is  not — as  Flechsig  claims— di* 
visible  into  a  larger  tract  which  degenerates  in  the  de- 
scending direction,  and  a  smaller  tract  which  "  does  not 
degenerate  for  long  distances  in  the  descending  direc- 
tion." 

To  internal  caiMule  de-    To  ansa  ^dnncmlaris^  aoootding  to  Fledi* 
generates  cephalad.  aig,  does  not  degenerattt  cq»faalad  (f). 


Lemnasoapedal 
tract  {RineUn- 
SchUifg  of  Moii- 
akow),  degenei^ 
ates  caudad  only. 


Origin  in  small  part  finom  ante- 
rior part  of  latenQ  column  (Ho* 
m^n's  case),  chief  origin  not 
definitely  determined,  but  pos- 
sibly frwn  posterior  columns. 


Division  in  middle  of  poMb 


Piniform  decus- 
sation to  nudet  of 
GoUandBurdach. 


The  degeneration  of  Flechsig*s  larger  portion,  as  in 
Hom6n's  case,  is  both  ascending  and  descending,  and 
in  that  case  the  impulse  to  descending  degeneration  was 
not  sufficient  to  carry  more  than  a  small  part  near  the 
periphery  of  the  anterior  third  of  the  lateral  column  be- 
low the  olives.  On  the  other  '|hand,  the  more  compact 
tract — that  is,  the  interolivary  portion — does  degener- 
ate in  the  descending  degeneration  for  its  entire  (known) 
anatomical  extent.  This  part  is  not  in  "immediate  juxta- 
position'* to  the  great  olives,  if  by  "great  olives  *'  the 
ganglionic  part  is  meant ;  in  the  upper  quarter  of  the 


1  Weber :  Mo 

*  Rosenthal :  Wiener  Me 


JahrbOcher,  1870^ 


voL  4<^  p.  xai,  1863; 


480 


THE  MEDICAL  RECORD. 


[November  1,  jgg. 


oblongata  it  touches  the  olivary  "halo,**  in  the  middle 
olivary  levels  the  inner  accessory  olive  (Fig.  4),  while  in 
the  lower  levels  a  large  mass  of  fibres  (Fig.  3)  inter- 
poses ;  this  latter  is  the  "  Vorderstrangsrest,''  or  remnant 
of  the  anterior  column. 

The  stratum  interolivare  (intermedium),  while  not  the 
largest,  is  the  most  distinct  of  the  lemniscus  fasciculi ;  it 
detaches  two  divisions,  a  larger  to  the  main  lemniscus,  a 
smaller  constitutes  the  lemnisco-pedal  tract,  which  latter 
is  a  constant  feature  in  the  l^igher  mammalia. 

Ascending  degeneration  in  the  case  of  a  lesion  affect- 
ing the  main  part  of  the  lemniscus  is  partial,  as  far  as  it 
can  be  traced  (in  my  case),  destroying  only  the  outer  part 
of  the  field  in  the  thalamus  region.' 

The  diagram  on  the  preceding  page  illustrates  the  re^ 
lation  of  these  different  parts. 

Since  in  Starr's  case  the  lemnisco-pedal  division  of 
the  interolivary  stratum  was  absent,  and  this  absence 
was  connected  with  absence  of  the  hemispheres,  and  as 
the  same  (?)  tract  was  degenerated  in  Monakow's  experi- 
mental ablation  of  the  cortex,  and  can  be  traced  by  di- 
rect anatomical  methods  (dog),  it  is  to  be  left  an  open 
question  whether  the  interolivary  tract  does  not  include 
fibres  having  centrifiigal  fimctions.* 

One  of  the  reasons  for  regarding  the  interolivary  stra- 
tum as  a  muscular-sense  tract,  is  that  this  is  the  only 
sense  which  can  be  allowed  to  decussate  from  the  poste- 
rior nuclei  in  such  fashion  as  this  stratum  does,  if  Brown- 
S^quard's  dictum  continues  to  bear  the  interpretation  it 
did  up  to  the  time  of  Ferrier's  experiment.  It  is,  how- 
ever, questionable  whether  it  is  the  sole  tract  for  im- 
pressions involved  in  the  mechanism  of  co-ordination  1 
There  is  a  singular  unanimity  in  the  description  of  the 
kind  of  ataxia  found  with  lesions  of  this  tract,  when  alone 
involved  it  relates  to  manipulation,  and  not  to  equilib- 
rium. The  latter  I  still  believe  to  be  a  function  which 
utilizes  the  paths  of  the  posterior  cerebellar  peduncle 
and  the  vestibular  branch  of  the  auditory  nerve. 

As  connected  with  this  question,  I  would  endorse  the 
exclusion  of  the  restiform  column  from  any  participation 
in  the  conveyance  of  pain  and  temperature  sensibility 
made  by  Starr ;  this  is  almost  a  self-evident  proposition. 
In  concluding  that  the  direct  myelo-cerebellar  tract  may 
set  up  reflex  vegetative  acts,  the  same  writer  advances  a 
suggestion  in  conflict  with  Flechsig's  statement  to  be  re- 
ferred to.  Visceral  sensations  are  not  unconnected  with 
the  unconscious  maintenance  of  the  equilibrium,  and 
hence  the  distribution  of  the  columns  of  Clarke  does  not 
appear  opposed  to  the  view  that  they  conduct  centri- 
petal impulses  regulating  the  equilibrium.  It  would  be 
singular,  if  the  cerebellum  were  a  visceral  reflex  centre, 
that  there  should  be  so  little  uniformity  in  its  develop- 
ment in  connection  with  the  uniformity  in  visceral  func- 
tions of  all  the  mammalia,  and  no  harmony  between  the 
development  of  any  portion  of  the  cerebellum  and  the 
greater  or  lesser  development  of  the  columns  of  Clarke 
adduced  to  support  this  theory.  The  association  of  vis- 
ceral lesions  with  cerebellar  disease  and  experimental 
lesion  of  the  restiform  column  is,  however,  a  noteworthy 
fact,  and  one  which  seems  to  necessitate  some  such  ex- 
planation as  the  one  suggested,  so  that  the  direct  cere- 
bellar tract  would  have  to  be  regarded  in  part  as  centri- 
petal (visceral  equilibrium  impressions)  and  in  part  as  a 
centrifugal  tract,  unless  the  visceral  reflexes  be  con- 
sidered as  travelling  in  a  different  channel  from  the  one 
carrying  the  unconscious  impressions  which  determine 
them.     Flechsig'  concludes  that  the  direct  myelo-cere- 

^  Over  a  year  ago  Hitziff  announced  before  the  German  alienists  and  neurolo- 
fl;ists  diat  he  had  observed  descending  degeneration  of  the  lemniscus  in  a  case  of 
bsion  in  the  crural  region.  His  promised  detailed  publication  has  not  yet  become 
accessible  to  me. 

*  There  is  this  difficulty  about  the  explanation,  if  arrest  of  development  is  insti- 
tuted eariy  enough  even  centripetal  tracts  are  involved  by  atrophy  of  the  station  to 
which  they  go. 

><Plan  of  the  Human  Brain,  p.  34.  I  cannot  agree  with  Flechsig  in  the  surmise 
expressed  in  his  sequel,  that  die  correspondence  of  the  sue  of  the  olives  in  the  ani- 
mal scale  harmonizes  with  that  of  the  dentated  nuclei,  or  that  both  depend  for  their 
common  developmental  grade  on  the  lenticular  nucleus  or  cerebellar  cortex. 
Flechsig  himself  adds  a  query  to  this  guess.  The  fact  is  that  in  a  scries  of  ani- 
mals, faieginning  ¥rith  the  marsupial  camivora  (opossum),  then  passing  through 


bellar  tract  conducts  in  a  centripetal  direction,  and  traces 
it  to  the  cerebellar  cortex ;  later,  in  the  same  treatise 
(p.  42^,  he  cautions  against  the  adoption  of  the  view  that 
exclusively  centripetad  conduction  occurs  in  the  direct 
myelo-cerebellar  tract  on  account  of  the  connection  of 
the  columns  of  Clarke  with  the  anterior  gray  horns.  May 
this  not  indicate  an  independent  reflex  arch  ? 

The  evidence  of  passive  (non-irritative)  lesion  of  the 
cerebellum  is  to  the  effect  that  it  is  not  essential  to  the 
proper  conduction  of  the  visceral  functions,  not  more  so 
than  the  cerebral  hemispheres.    The  argument  contained 
in  the  following  :  <<  It  is  a  noticeable  fact  that  these  symp- 
toms  of  cerebellar  disease  (indigestion,  vomiting  of  a  p^ 
culiar  kind,  obstinate  constipation,  polyuria,  albuminuria) 
unlike  the  ataxia,  are  not  produced  by  lesions  of  the 
vermiform  lobe  alane^  but  occur  when  the  cerebellar  hemi- 
spheres are  the  seat  of  lesions,  such  as  abscess  and  soft- 
ening from  embolism  and  thrombosis,  which  neither  in- 
crease  the  intracranial  pressure  nor  affect  in  anyway 
directly  the  floor  of  the  fourth  ventricle  and  the  pneumo- 
gastic  centres  there  or  in  the  flocculus," '  takes  no  account 
of  the  fact  that  Flechsig's  method  teaches  that  the  direct 
cerebellar  tract  connects  with  the  neighborhood  of  the 
vermiform  lobe  (Mittelstiick)  as  contrasted  with  the  lat- 
eral parts ;  or  if  it  does  take  this'  into  account,  must  as- 
sume an  irritative  influence  by  transmission  from  part  to 
part     Without  venturing  to  pronounce  adversely  to  this 
theory,  I  offer  the  above  considerations,  leaving  it  to  in- 
vestigations I  am  at  present  concerned  with,  to  contrib- 
ute fiu-ther  facts  to  this  interesting  question.' 

As  the  posterior  columns  are  small  in  the  porpoise  and 
inadequate  to  the  formation  of  the  restiform,  it  is  to  be 
assumed  that  the  direct  myelo-cerebellar  tract  is  very 
large  in  this  animal  This  tract  is  connected  with  the 
columns  of  Clarke,  whose  extent,  in  the  cord,  corresponds 
closely  to  the  extent  of  those  body  segments  in  whidi  the 
great  viscera  are  collected.  In  the  porpoise,  as  in  all  the 
cetacea  and  the  phocidae,  the  visceral  cavities  are  un- 
usually large,  and  the  viscera  themselves  more  compli- 
cated than  in  related  animal  groups.  The  cells  of  the 
columns  of  Clarke  resemble  in  shape  those  of  nerve 

some  rodentia  to  the  placental  camivora,  the  ape  and  man,  there  is  a  paraDd  rae 
and  homology  of  type  b  aU  these  p&rts.  In  the  elephant  and  porpoise,  howwer, 
notwithstanamg  theu-  enormous  cerehellum,  the  olive  is  of  no  higher  a  grade  of  de- 
velopment than  in  the  hippopotamus.  (In  the  elephant  the  olivary  lamma  is  dhr 
bulky.)  If  any  evidence  were  to  be  derived  from  comparative  anatomy,  it  vodd 
show  that  there  are  two  types  of  olivary  development,  one  marked  by  a  progreanc 
complication  of  the  dentictilate  part  of  the  olive  found  m  animals  with  firedy  mov^ 
able  digiti,  and  one  in  which  ttie  accessory  nudei  nearlv  equaL  or  even  prq»a- 
derate  over  the  main  U-shaped,  respectivdy  dcnute  nucleus,  which  is  the  case  m 
the  pachydermata  and  the  cetacea,  who  are  in  no  case  endowed  with  free  dij^ 
motion  and  co-ordination.  But  for  the  ^>parent  connection  between  digital  v» 
tivity  and  olivary  type,  I  would  hazard  the  suggestion  that  the  development  of  ifae 
olives  suggests  a  grcsiter  affinity,  zoologically  speaking,  between  the  pachydenuli 
and  the  cetacea  than  I  have  hitherto  been  mcuned  to  admit  (Recent  Studies  m 
Localization,  Chicago  Journal  of  Nervous  and  Mental  Diseases,  zBjj). 

>  Starr,  loc  dt,  p.  63. 

*  Comparative  Anatomy  is  competent,  I  think,  to  setde  some  of  the  questioos  indi- 
cated. In  the  porpoise  the  relations  are  most  aberrant  In  the  usual  sttoatioo 
there  are  no  pyramids,  nor  a  decussation  either  of  pyramid  or  interolivary  fibns. 
There  is  but«««  of  the  nuclei  of  the  posterior  columns,  in  anything  like  ue  ordi- 
nary development,  and  an  atrophic  state  of  the  posterior  columns  generally  in  the 
uppermost  cervical  levels.  The  "  Vorderstrang-gnmdbilndel  **  of  Flficfasig  «r 
enormous,  and  consequently— the  only  exception  to  the  rule  in  mammals— the  aa- 
terior  (ventral)  fissure  of  the  cord  is  deeper  than  the  posterior  in  diis  regiao. 
Connected  with  this,  probably,  is  the  fiur^that  the  posterior  lons;itudittal  fiusdoiksi 
and  the  inner  division  of  the  reticular  field  are  unusually  large,  oonstitutii«  a 
united  area  which  is  paralld  to  the  raj^ie.  The  nucho-doraal  mnervatioas  prob- 
ably pass  through  this  tract.  There  is  a  raphe,  but  unlike  that  of  man,  it  is  tbisMr 
ventrad  than  toward  the  nerve  nudei,  where  it  is  double  the  width  of  other  poiDB» 
and  sends  out  the  only  powerfiil  lateral  processes  it  boasts  of  in  the  coRcapoadiH 
parts  of  the  oblongata.  The  two  olivary  nudd  approach  each  other  as  in  die  ds- 
phant,  and  do  not  resemble  in  type  die  olivary  nudd  of  th^  camivora,  bat  ifae 
padiydermata  (hippopotamus,  horse,  and  elq>lian^.  The  araform  fibces  of  ik 
olivary  decussational  commissure  do  not  tadce  a  course  so  near  die  latenJ  field  d 
the  oblongata  as  in  man,  but  condensing  in  powerful  strands  break  into  vtaH 
seems  to  represent  die  restiform  column  from  the  middle  of  the  reticular  fidd.  b 
some  levds  there  is  no  fissure  nor  raphe  between  the  olives  in  dieir  ventral  portioas. 
The  main  accession  to!  the  represenutive  of  the  restiform  'vJ«»"«t*  appears  t»  be 
the  direct  transition  of  fibres  from  the  posterior  column  through  a  fidd  anaJocoai 
to  (/^  3  Fig.  3)  die  arched  fibre  fidd  which  interpolates  itself  between  die  nudea 
of  RoUndo  and  Burdach,  and.  which  as  its  partial  fi«edom  from  degenciadae  is 
my  case  shows,  embodies  fibres  independent  of  the  interolivary  stratum.  Ttac 
sqipears  still  more  cephakd  to  be  a  bodily  transposition  of  the  posterior  colo  ik 
restiform  column. 

At  die  junction  of  the  oblongata  to  the  pons  there  is  a  .powerfril  fibce  sjsaeo^ 
identified  by  the  naked  eve,  which  may  indicate  a  decnssataon  of  ventFd(p^aad 
or  intermediate)  fibres  (?),  but  in  connection  with  this  there  is  also  a  devdaoBeal 
of  a  lateral  ventral  mass,  attached  to  the  auditory  nerve,  which  is  thus  nriot 
known  to  be  paraUded  in  mamma|;aTi  anatomy. 

The  pons,  notwithstanding  its  great  apparent  surfiice  development,  is  tUD,  ikat 
is,  of  slight  dorso-ventral  extent,  and  consists,  as  in  ihe  dephant,  of  transverse  fibti 
and  ganglia  exdusivdy ;  there  are,  as  in  the  dephant,  no  kmgitudinal,  ».«.,  pyis* 
mid  fibres.  Between  the  tegmentum  and  the  pons,  there  is  a  sjrsiem  of  oent- 
bundles'imbedded  in  ganglionic  matter,  which  resemble  in  disposition  the  Vamm> 
pedal  bundle. 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


481 


nuclei  known  to  be  related  to  visceral  functions.     It 
woald,  therefore,  as  far  as  the  case  of  the  porpoise  stands, 
be  a  confirmation  of  the  view  that  the  columns  of  Clarke 
and  the  cerebellum  which  derives  fibres  from  them  through 
the  direct  myelo-cerebellar  tract,  have  a  relation  to  visceral 
fiiDCtions ;  the  mother-bed  of  the  direct  myelo-cerebellar 
tract  corresponding  in  extent  to  the  visceral  segments,  and 
its  cells  corresponding  in  shape  to  those  known  to  have 
relations  to  the  viscera.     One  end  of  the  Purkinjean  cell 
of  the  cerebellum,  too,  is  as  Meynert  has  ingeniously 
indicated,  of  a  similar  structure.    If  any  inference  is  to  be 
drawn  from  cell  structure  as  to  function,  then  the  Pur- 
kinjean cell  is  a  mediator  between  a  visceral  centripetal 
tract  and  a  cerebral  one,  connected  with  the  information 
of  the  motor  centres  as  to  the  space  sense.     The  case  of 
the  porpoise  speaks  as  loudly  for  the  *'  equilibrium  "  as 
for  the  '*  visceral ''  theory,  inasmuch  as  the  wonderfully 
co-ordinated  movements  of    the   porpoise   are^  chiefly 
carried  out  by  the  trunk  muscles.' 

It  it  evident  that  within  a  large  area  of  the  medulla 
oblongata,  one  covering  its  entire  field,  with  the  excep- 
tion of  the  pyramid  tract,  and  the  apparatus  of  the  nerve 
nuclei,  we  must  look  for  the  centripetal  tracts  which  in- 
form the  Psyche  of  the  contacts  with  the  outer  world, 
the  visceral  sensations,  and  the  muscular  sense.    Many  of 
the  movements  dictated  by  the  perfective  economical 
needs  of  the  body  are  not  directly  mediated  through  the 
apparatus  of  consciousness,  indeed  many  of  them  are 
absolutely  removed  firom  the  control  of  the  Psyched  That 
the  translation  of  the  peripheral  impression  to  the  cen- 
trifugal impulse,  in  their  case,  takes  place  without  the 
intervention  of  the  cerebrum,  is  evident    The  ganglionic 
apparatus  of  the  cord,  and  in  higher  degree  of  the  ob- 
longata, suffice  for  these  objects.     It  is  a  fact  of  signifi- 
cance, that  of  the  reflex  and  automatic  actions  which  are 
made  to  serve  these  objects,  those  determined  in  the 
mesencephalon,  pons,  and  oblongata  far  exceed  in  com- 
plexity and  elaboration  those  of  the  cord,  and  in  direct 
proportion   to  this  complexity  and  elaboration  do  they 
display  an  approach  to  intelligence.     It  is  a  dogma  of 
physiology  that  all  the  intricate  automatisms  of  the  brain- 
aris,  be  they  subservient  to  respiration,  thermic  regula- 
tion, or  nutrition,  depend  for  their  origin  and  develop- 
ment on  impressions  indicating  the  nature  of  the  organic 
need.* 

We  must  here  assume  as  an  element  in  our  calculations, 
that  the  area  of  the  oblongata  within  which  we  are  seek- 
ing for  the  centripetal  tracts,  includes  some  which  we 
may  never  be  able  to  determine,  because  their  disturb- 
ance is  not  made  manifest  to  consciousness,  not  dis- 
coverable by  instruments  of  precision,  and  cloaked  by 
vicarious  action  of  the  symmetrical  ganglionic  apparatus. 
While  unilateral  irritative  lesions  may  enlighten  us  in 
this  field,  through  positive  symptoms  produced,  suhirac- 
iion  lesions  *  must  be  bilateral  in  most  cases  to  do  so. 

There  are  other  functions,  carried  on  by  centripetal 
tracts,  which  are  subservient  to  needs  which  constitute  a 
connecting  link  between  the  vegetative  and  deliberate 
purposes  :  they  regulate  the  bodily  equilibrium.  Not- 
withstanding the  niany  objections  repeatedly  urged  to  the 
older  view  regarding  the  cerebellum,  the  proposition  for- 
mulated by  me  some  years  ago,  that  a  skilful  and  rapid 
co-ordination,  associated  with  a  good  sense  of  rhythm, 
space,  and  time  in  connection  therewith,  was  not  possible 
without  an  intact  and  well-developed  cerebellum,  does 
not  seem  to  be  invalidated  by  any  authentic  case,  while 
it  is  confirmed  by  a  large  number  of  observations. 

The   higher  form  of  sensation,  that  of  conscious  per- 


s? 


^  Tilts  animal,  provided  with  dumsy  flippers  and  a  rudimentary  dorsal  fin,  is  ca- 
pable of  executing  evolutions  exceeding  anything  in  the  vertebrate  domain,  not  ex- 
— idag  the  blinded  bats  of  Spallanani,  for  tbey  mvolve  at  once  gross  force  and  skill. 
~  porpoise  executes  his  remarkable  evolutions  around  his  own  axis,  while  rush- 
_    Mog  with  the  speed  of  a  steamer,  and  it  is  a  notorious  fact  that  cohabitation 
— aa  act  reauiring  the  ordinarv  mammalian  mechanism — is  carried  on  while  the 
herd  as  iumDUas  along  with  undiminished  speed.    All  it  done  by  the  axial  muscles. 
s  fortunately  too ! 

*  I  do  not  enter  here  into  a  discussion  of  Van  der  Kolk's  beautiful  theory  of  res- 
the  outcome  of  a  direct  rhythmical  asphyxia  of  the  oblongata. 
I  involving  elimination  of  nervous  mechanisms. 


ception,  travels  through  the  area  left  over  after  the  sub- 
traction of  the  cerebellar  tracts.  Inasmuch  as  there  is 
an  intimate  dovetailing  of  lemniscus,  reticular,  and  cere- 
bellar tracts  in  this  area,  in  the  lower  half,  and  indeed 
nearly  in  the  entire  level  of  the  oblongata,  accurate  and 
positive  conclusions  as  to  the  differentiation  of  pain 
thermic,  and  tactile  tracts  in  the  reticular  formation  and 
lemniscus,  can  be  derived — as  far  as  the  study  of  single 
cases  is  concerned — from  such  only  where  the  focus  of 
disease  is  situated  above  the  level  of  the  fully  formed 
posterior  cerebellar  peduncle.  Of  these  forms  of  sensa- 
tion, the  highest,  or  rather  the  one  made  subservient  to 
the  most  intellectual  purposes,  is  the  stratum  interolivare, 
which  conveys  the  so-called  muscular  sense  brainward, 
for  the  purpose  of  facilitating  skilful  employment  of  the 
psycho-motor  centres.  All  studies  made  so  far  fail  to 
give  any  satisfactory  account  of  the  raiscn  (P/tre  for  the 
paradoxical  phenomenon  observed  by  Brown-S6quard — 
that  the  tract  for  one  sense,  which  is  in  part  but  a  refine- 
ment of  associated  peripheral  impressions,  should  not  de- 
cussate in  the  cord,  but  decussate  in  the  oblongata,  while 
the  others  should  decussate  in  the  cord,  and — ^redecussa- 
tion  being  fairly  excluded,  inasmuch  as  that  assumption 
would  be  still  more  out  of  harmony  with  the  facts  than 
any  other — not  decussate  in  the  oblongata.  There  is  no 
physiological  theory,  nor  mechanical  factor  of  develop- 
ment, nor,  as  yet,  are  there  adequate  anatomical  paths,  to 
explain  why  the  ordinary  sensory  channels  should,  so  soon 
after  their  entry,  seek  the  opposite  side  of  the  cord  to 
travel  brainward  in.  It  is  for  this  reason,  I  believe,  that  / 
so  many  teachers  of  cerebral  anatomy  have  contented 
themselves  with  tracing  the  great  tracts  from  and  to  the 
level  of  the  first  cervical  nerve-root,  until  Wernicke  for- 
mally opened  a  question — ^and  answered  it  as  satisfac- 
torily as  any  one  up  to  the  present— which  had  probably 
confiised  or  puzzled  all  of  his  co-laborers. 


ON  THE  NERVOUS  ORIGIN  OF  SOME  DISOR- 
DERS OF  THE  ALIMENTARY  CANAL.' 

By  LEONARD  WEBER,  M.D., 

NSW  Y<ntK. 

The  following  observations  on  the  often  misunderstood 
disturbances  of  the  gastro-intestinal  tract  of  nervous  ori- 
gin will  contain  nodiing  new  to  those  familiar  with  the 
diseases  of  the  nervous  system,  but  will  be  of  interest  to 
the  practitioner,  I  believe.  As  to  the  theory  of  these 
affections,  it  must  be  remembered  that  Leube,  in  an  arti- 
cle entitled  **  Dyspepsia  Nervosa  "  {Deutsche  Zeitsch.  fOr 
Klin,  Med.\  thought  the  latter  to  be  peripheral  neurosis 
of  the  stomach,  affecting  the  central  nervous  system  by 
reflex  only.  It  cannot  be  denied  that  such  cases  may 
occur,  but  they  are  certainly  very  rare. 

I  believe,  with  Beard,  F.  Richter,  Mobius,  Leyden, 
Burkart,  and  others,  that  nervous  dyspepsia,  eta,  is  not 
of  local  origin,  but  a  symptom  of  general  neurosis,  par- 
ticularly of  cerebro-spinal  neuras&enia.  Organic  dis- 
eases of  the  nerve-centres  may,  also,  reflex  severely  upon 
the  functions  of  the  stomach,  when  the  pneumogastric 
centre  or  the  cervical  portion  of  the  cord  or  the  abdom- 
inal ganglia  of  the  S3rmpathetic  have  become  the  seat  of 
lesions. 

Between  twenty  and  thirty  per  cent,  of  patients  with 
organic  nervous  disease  have  gastric  or  intesdnal  dis- 
turbances. Periodic  vomiting  and  retching — crises  gas- 
triques  of  Charcot — often  constitute  prominent  and  early 
symptoms  of  typical  tabes,  but  they  have  been  observed 
also  in  subacute  myelitis,  disseminated  sclerosis,  and 
progressive  paralysis.  But  similar  paroxysms  of  severe 
retching  and  vomiting,  associated  with  violent  ^stric 
pain,  great  tenderness  in  the  epigastrium,  and  the  impos- 
sibility to  retain  food,  lasting  for  two  weeks  and  more, 
simulating  gastritis  or  ulcer,  and  presenting  considerable 

>  Read  at  the  meeting  of  the  New  York  Neurological  Society,  October  j,  1884. 


482 


THE  MEDICAL  RECORD. 


[November  1,  1884, 


difficulties  of  dis^osis,  have  been  observed  occasionally 
independent  of  anatomical  changes  in  the  stomach  or  cen- 
tral nervous  system.  Leyden,  in  an  article  on  **  Periodical 
Vomiting  and  Gastralgia,"  published  in  the  Deutsche 
Zeitsch.filr  Klin,  Med,,  iv.,  4,  p.  605,  x88a,  reports  four 
cases,  one  of  them,  in  a  man  forty  years  of  a^e,  coming 
on  after  protracted  mental  overwork,  and  endmg  fatally. 
I  have  had  two  well-marked  cases  of  the  kind  under  my 
charge,  both  concerning  young  women,  in  the  etiology 
of  which  menstrual  disturbances  played .  an  important 
part  Ice  applications,  morphine  injections,  and  the 
blandest  possible  diet  failed  to  bring  relief.  But  after 
raising  a  blister  over  the  stomach,  putting  neither  food 
nor  drink  into  it,  and  supporting  the  patients  by  rectal 
alimentation  for  some  days,  improvement  and  final  re- 
covery took  place.  Constipation  and  diarrhoea,  hyper- 
sesthesia  aild  neuralgia  of  the  stomach,  are  quite  frequent 
in  neurotic  females,  particularly  when  they  have  uterine 
trouble.  In  neurasthenic  men,  diarrhoea,  quite  inde- 
pendent of  catarrh  or  other  local  causes,  is  not  very 
rare.  An  interesting  and  obstinate  case  of  periodical  at- 
tacks of  nervous  diarrhoea  has  been  under  my  observa- 
tion for  some  years.     F.  S ,  about  forty  years  of  age, 

a  merchant,  the  father  of  healthy  children,  of  strong  con- 
stitution, excessively  nervous,  showed  the  first  symptoms 
of  the  disorder  eight  years  ago,  while  engaged  m  active 
and  difficult  business.  He  has  been  carefully  examined 
by  myself  and  others,  and  had  the  counsel  of  eminent 
specialists.  But  no  one  has  arrived  at  an  anatomical 
diagnosis  in  his  case ;  a  nervous  origin  of  it  is  almost 
certain,  the  more  so  as  his  father,  who  is  still  alive,  has 
been  suffering  from  the  same  trouble  for  many  years. 

Various  modes  of  treatment  have  given  but  temporary 
relief,  the  attacks  growing  rather  more  severe  and  per- 
sistent as  time  goes  on,  and  are  frequently  complicated 
by  vomiting  and  gastralgia.  Having  found  that  he  can 
make  himself  more  comfortable  by  morphia  than  by  any 
other  remedy,  the  patient  has  of  late  become  somewhat 
of  a  morphine-eater.  The  rather  frequent  and  more 
readily  tractable  forms  of  nervous  dyspepsia,  etc.,  we 
may  designate,  with  R.  Burkart,  as  gastric  neurasthenia. 
The  difficulties  and  discomforts  experienced  while  di- 
gestion goes  on,  constitute  the  principal  complaint  in 
these  cases.  All  other  intercurrent  symptoms  depend 
upon  the  exacerbation  and  remission  of  the  former. 

Such  other  cerebro-spinal  symptoms  are  headache,  ver- 
tigo, cardiac  palpitation,  backache,  depression  of  spirits, 
disturbed  sleep,  etc.  This  array  of  symptoms  gives  us 
a  clinical  picture  quite  different  from  the  symptomatology 
of  catarrh,  carcinoma,  or  gastric  ulcer. 

There  is  often  a  sensation  of  fiilness  and  pressure  in  the 
epigastric  region,  frequent  eructation,  occasional  vomit- 
ings tympanites,  and  flatulency.  Sometimes  there  is  ano- 
rexia, and  again  ravenous  appetite ;  bowels  generally 
irregular,  alternately  loose  and  constipated. 

R.  Burkart,  in  an  excellent  monograph  on  '*  Neuras- 
thenia Gastrica,''  Bonn,  1882,  descries  a  new  symptom, 
ue,y  hjrperaesthesia  of  the  abdominal  ganglia  of  the  sym- 
pathetic. He  has  found  it  in  almost  all  his  cases  of 
neurasthenia  gastrica,  and  mentions  three  localities  for 
examining  for  the  tender  ganglia  :  i.  Plexus  hypogas- 
tricus.  The  patient  being  in  the  horizontal  position, 
pressure  is  made  with  two  fingers  of  both  hands  in  the 
median  line,  below  the  umbilicus  and  a  little  above 
a  line  that  would  connect  the  spin.  oss.  ilei,  perpen- 
dicularly downward  against  the  vertebral  column.  In 
neurasthenia  gastrica  we  shall  find  in  this  way  an  ex- 
quisitely tender  spot,  from  which  painful  sensations  will 
radiate  downward  and  particularly  upward.  A  feeling  of 
oppression  will  sometimes  come  over  the  patient  while 
the  pressure  lasts.  A  second  place  corresponds  to  the 
plexus  coeliacus;  but  pressure  over  that  discloses  less 
hyperaesthesia,  and  reflex  symptoms  are  absent.  Finally, 
the  plexus  aorticus  may  also  be  the  seat  of  hyperaesthesia. 
Per  contra,  he  has  not  found  any  hyperaesthesia  of  the 
above  ganglia  in  neurasthenia  without  gastric  symptoms. 


nor  in  cases  of  anatomical  disease  of  the  gastric  intes- 
tinal tract 

The  disproportion  between  the  objective  signs  and  the 
numerous  complaints  is  quite  characteristic,  and  the  dis. 
comfort  is  sometimes  greater  when  the  stomach  is  empty 
than  when  it  is  full.  While  diet  has  no  ^eat  influence, 
emotion,  worry,  and  excitement,  and  mtellectual  or 
physical  overwork  have  so  much  the  more  in  precipitat- 
ing an  attack.  The  condition  of  the  patient  is  variable; 
there  are  periods  of  great  distress,  followed  by  partial  or 
complete  well-being. 

The  morbid  influences  most  potent  in  producing  gastiic 
neurasthenia  are :  acute  diseases,  intellectual  overwork, 
great  emotion  and  excitement,  hereditary  neuroses,  and 
the  various  sins  of  civilized  life.  The  prognosis  of  this 
class  of  cases  is  generally  favorable.  Therapeutically 
they  need  generous  quantities  of  nutritious  food,  good 
air,  and  particularly  mountain  air,  and  ought  to  follow  a 
suitable  regime  in  sexual  indulgence,  and  in  mental  and 
physical  occupation.  Bitter  waters  and  saline  purgatives 
in  general  are  contra-indicated,  according  to  my  experi- 
ence. The  waters  of  Saratoga,  Carlsbad,  and  similar 
places  do  harm,  and  the  more  so,  the  stricter  the  diet  that 
has  been  observed  while  using  them.  I  have  seen  patients 
of  that  class  come  back  from  Carlsbad  worse  than  they 
were  before  they  went.  Hydrotherapeutics  in  the  shape 
of  tepid  half-baths  with  cold  afliisions,  or  the  wet  sheet 
with  friction  of  the  whole  surface  of  the  body,  are  often  of 
service,  and  so  is  massage,  generally  and  gently  applied 
Galvanism  applied  every  other  morning  to  head,  spine, 
or  sympathetic,  according  to  the  indications  of  the  case, 
is  frequently  of  good  influence.  Of  drugs  I  am  in  the 
habit  of  prescribing  small  doses  of  an  acid  solution  of  the 
comp.  hypophosphites  between  meab,  more  than  any- 
thing else.  They  are  generally  well  borne  by  the  stom- 
ach, and  I  consider  them  a  good  tonic  for  a  neuras- 
thenic person. 

as  Wist  Forty-iixth  Stxbbt,  New  Yokx. 


MINERAL  ASTRINGENTS   AND   CAUSTICS  IN 
OPHTHALMIC   PRACTICE. » 

By  EDWARD  S.  PECK,  M.D., 

VISITING  6URGKOM  TO  CHARITY  HOSTITAL,  NSW  YORK. 

The  motive  of  this  paper  was  suggested  to  me  by  re- 
marks made  by  a  member  of  this  Society,  some  time  ago, 
relative  to  the  use  of  various  mineral  astringents  and 
caustics  in  the  treatment  of  eye  diseases.  It  occurred 
to  me  that  it  would  not  be  amiss  to  offer  the  present  views 
of  their  use,  with  special  reference  to  nitrate  of  silver,  as 
a  monthly  contribution,  and  to  endeavor  to  differentiate 
their  position  in  ophthalmic  pharmacology. 

Conjunctivitis. 

The  different  forms  of  conjunctivitis  may  be  classified 
as  catarrhal,  vernal,  follicular,  granular,  blennorrhdic^ 
croupous,  diphtheritic,  and  phlyctenular, 

a.  Catarrhal  conjunctivitis^  or  conjunctivitis  simfUx, 
— ^The  general  characters  of  this  affection  are  increased 
hyperaemia  of  the  conjunctiva  and  increased  secretion. 
The  hyperaemia  is  often  very  pronounced  ;  the  secretion 
is  purely  catarrhal,  consists  of  mucus,  epithelium,  and 
fat-cells,  is  a  trifle  opaque,  viscid,  and  when  it  becomes 
dry  the  lid-edges  are  disposed  to  stick  together. 

Every  abnormal  secretion  of  the  conjunctiva,  produced 
b^  inflammatory  processes,  is  to  be  regarded  as  conta- 
gious. 

A  simple  catarrhal  conjunctivitis  is  not  always  am^ 
nable  to  treatment ;  it  may  become  chronic  ;  or  it  may 
produce  lymphatic  infiltration  in  the  vicinity  of  the  cul- 
de-sac  ;  or  it  may  involve  enough  of  the  under-lid  to 
create  an  eversion  of  the  lachrymal  puncta ;  or  there 
may  be  an  ulcerative  blepharitis,  or  a  secondary  trau- 

>  Read  before  the  Nortfawestem  Medical  and  Surgical  Socieqr,  April  z^  in4- 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


483 


matic  keratitis.  Such  are  some  of  the  naembers  of  the 
vicious  circle  possible  to  every  acute  catarrh  of  the  con- 
junctiva. 

As  regards  the  use  of  nitrate  of  silver  in  the  different 
forms  of  conjunctivitis,  Graefe  *♦  elaborated  the  princi- 
ples to  be  carried  out  in  a  masterly  paper  on  diphtheria 
of  the  conjunctiva.  His  work  in  this  direction  rehabili- 
tated the  caustic  from  the  disrepute  into  which  it  had 
fallen.  The  empirical  use  of  the  silver-nitrate  is  un- 
necessaiy,  inasmuch  as  its  indications  in  different  forms 
of  conjunctivitis  are  tolerably  precise.  Some  of  these  in- 
dications I  desire  to  note  here  :  • 

1.  The  use  of  silver-nitrate  always  presupposes  an  in- 
creased flow  of  blood  to  the  conjunctiva,  with  a  certain 
amount  of  succulence  of  tissue  and  serous  exosmosis ; 
and  the  more  pronounced  the  hyperaemia  of  the  mem- 
brane with  its  secondary  developments,  the  more,  cateris 
paribus^  is  the  nitrate  indicated. 

2.  Silver-nitrate  is  not  indicated  in  any  form  o!  con- 
junctivitis attended  by  a  fibrinous,  easily  coagulable  se- 
cretion, so  long  as  this  kind  of  secretion  persists.  It 
frequently  happens  that  blennorrhoic  affections  of  the 
conjunctiva  have  an  initial  stadium,  in  which  the  secre- 
tion is  easily  coagulated  when  the  superficies  of  the 
membrane  is  smooth  and  glistening  on  account  of  a 
highly  injected  mucous  membrane.  To  apply  the  silver- 
nitrate  on  such  a  membrane  would  be  to  impair  its  integ- 
rity, to  increase  the  fibrinous  exudation,  and  possibly 
to  induce  a  severe  disease  of  the  cornea. 

3.  Silver-nitrate  is  contra-indicated  in  deeper  inflam- 
matory processes  of  the  eye,  as,  for  instance,  in  certain 
diseases  of  the  cornea. 

4;  The  strength  of  the  nitrate  must  be  in  proportion  to 
the  intensity  of  the  inflammatory  changes  of  the  conjunc- 
tiva ;  that  is  to  say,  a  severer  grade  of  conjunctival  in- 
flammation demands  a  stronger  solution  of  the  nitrate. 
These  solutions  vary  from  a  half  to  one  and  a  half  per 
cent. 

5.  The  strength  of  the  nitrate  must  be  reduced  in  pro- 
portion to  the  disappearance  of  the  inflammation. 

6.  An  eschar  forms  after  the  application  of  the  nitrate, 
under  which  regeneration  of  the  disturbed  tissues  takes 
place.  The  nitrate  should  not  be  reapplied  until  after 
the  regeneration  of  the  tissues. 

7.  The  influence  of  the  nitrate  upon  other  tissues  should 
be  prevented  ;  for  this  purpose  either  simple  water  should 
be  used  to  wash  away  the  resulting  silver-albuminate,  or 
with  stronger  solutions  of  silver  a  solution  of  common 
salt  should  be  used. 

The  details  of  application  need  not  be  given  here.  It 
is  sufficient  to  note  that  silver-nitrate  is  the  astringent  to 
be  used  over  all  others  in  catarrhal  conjunctivitis. 

h.  Vernal  conjunctivitis, — ^This  is  an  endemic  form  of 
catarrh,  showing  itself  in  the  spring.  It  is  confined  to  the 
limbus  conjunctivae  and  to  the  adjacent  part  of  the  bul- 
bar conjunctiva.  As  a  rule,  there  is  no  excess  of  secre- 
tion, and  the  affection  is  to  be  regarded  as  a  chronic 
conjunctivitis.  The  membrane  is  of  a  dirty  red  or  a 
lustreless  pink  color ;  it  lacks  the  freshness  and  vitality 
peculiar  to  other  forms  of  conjunctival  injection.  This 
is  probably  due  to  a  serous  infiltration  which  occurs  in 
irregular  spots  under  the  conjunctiva.  The  disease  is 
marked  by  unusual  photophobia. 

To  the  inexperienced  practitioner  there  is  a  great 
temptation  to  use  the  silver-nitrate,  but  it  will  only  in- 
crease the  symptoms,  and  thereby  possibly  endanger  the 
cornea.  In  the  event  of  a  discharge,  a  weak  solution  of 
silver-nitrate,  as  one  per  cent.,  could  be  used  with  bene- 
fit The  photophobia  must  be  regarded,  however,  as  con- 
tra-indicating the  use  of  silver ;  such  metals  as  zinc  or  lead 
would  be  preferable. 

c.  Follicular  conjunctivitis^  properly  named  from  the 
development  of  superficial,  globular,  pale-red  promi- 
nences, which  accompany  catarrhal  inflammatory  changes 

>  Von  Graefe  :  Arch.  £  Ophtfaal.,  vol.  L,  part  i.,  pp.tz6B-a5o. 


in  the  conjunctiva,  and  which  latter,  on  subsiding,  carry 
away  with  them  quite  every  vestige  of  follicular  growth. 
Follicular  differs  from  simple  catarrh  in  this  development 
of  follicles.  Like  simple  catarrh  it  has  a  secretion  mild 
in  character,  while,  unlike  it,  the  follicles  may  be  regarded 
as  lymph-follicles ;  that  is  to  say,  their  structure  is  that  of 
the  closed  lymph-sacs,  while  the  smaller,  smooth,  whitish 
bodies  may  be  regarded  as  collections  of  lymphoid  ele- 
ments. To  carry  out  the  analogy  between  the  follicular 
and  catarrhal  forms,  it  is  to  be  said  that  the  development 
of  follicles  protracts  the  course  of  a  conjunctivitis,  renders 
it  more  obstinate  to  absorption  processes,  and  more  dis- 
posed to  a  recurrence ;  on  the  contrary,  there  are  not 
the  inflammatory  changes  in  the  deeper  tissues  of  the  lid 
in  follicular  conjunctivitis  which  obtain  in  granular  con- 
junctivitis. 

Secretion  of  an  acute  follicular  is  more  contagious  than 
of  a  simple  catarrh  of  the  conjunctiva.  This  is  the  form 
usually  found  in  the  different  members  of  a  family,  in 
schools,  barracks,  etc.,  though  other  causes  may  conspire 
to  extend  the  eye  disease,  chief  of  which  is  the  bad  ven- 
tilation of  such  inhabited  rooms.  Among  the  causes  of 
follicular  conjunctivitis  is  to  be  reckoned  die  traumatism 
due  to  a  long-continued  use  of  irritating  remedies,  such  as 
different  mercurial  ointments  applied  within  the  lids,  so 
much  in  vogue  in  South  Germany,  atropine,  etc.  Although 
atropine  may  have  been  used  for  weeks  without  any  con- 
junctival reaction,  suddenly,  without  any  warning,  a  fol- 
licular inflammation  of  the  conjunctiva  may  be  developed, 
with  marked  injection  and  oedema  of  the  lower  lid,  which 
latter  may  extend  to  the  lid  border,  and  eventuate  in  a 
blepharitis,  or  may  go  over  on  the  integument  of  the  lid 
and  cheek,  amounting  to  a  dermatitis  miliaris.  One 
peculiarity  of  atropine-conjunctivitis  is  its  long  duration 
and  resistance  to  treatment;  these  characteristics  are 
entirely  independent  of  the  length  of  time  atropine  has 
been  already  used,  whether  long  or  short. 

As  to  the  management  of  cases  of  follicular  conjunc- 
tivitis, it  is  to  be  observed,  that  fwhile  silver-nitrate  is  the 
astringent  of  all  others  to  be  relied  on,  it  is,  however,  not 
to  be  used  early  in  the  case.  Antiphlogistic  measures  are 
first  to  be  resorted  to ;  such  as  ice-cloths,  of  one  thick- 
ness of  a  square  of  old  muslin,  transferred  from  raw  ice  to 
the  eye;  scarifications,  if  the  lid  is  hyperaemic  and 
swollen,  made  parallel  to  the  fold  of  the  lid;  while  later, 
and  not  until  the  incisions  have  healed,  the  silver-nitrate, 
not  stronger  than  one  per  cent.  It  goes  without  sa3ring, 
that  all  such  cases  must  be  eliminated  of  their  hygienic- 
ally  bad  relations,  placed  in  new  rooms,  or,  at  least,  in 
freshly  fumigated  old  rooms,  as  when  the  treatment  is 
conducted  in  the  wards  of  a  hospital,  the  dormitories  of 
lodging-houses,  boarding-schools,  etc. 

d.  Granular  conjunctivitis. — ^The  general  characteris- 
tics of  this  form  of  conjunctivitis  are  so  well  known  that 
it  will  be  hardly  necessary  to  enter  into  a  detailed  ex- 
planation of  its  pathological  exhibits;  it  has  vaiious 
forms,  which  are  arranged  under  different  names,  and 
require  different  plans  of  treatment  according  to  the 
different  stadia  of  the  pathological  process.  The  terms 
granulations,  trachoma,  etc.,  imply  technical  states  and 
qualities  of  the  granular  and  granulating  process.  An 
analogy  is  often  drawn  between  this  and  the  follicular 
form  of  conjunctivitis ;  but  the  similarity  is  external  and 
superficial,  and  is  based  upon  the  fact  of  the  formation  of 
prominences  on  one  and  the  same  conjunctival  tissue. 
The  follicles  in  the  one  variety  are  purely  superficial,  and 
disappear  without  leaving  a  trace  of  their  existence; 
while  the  granulations  are  formed  from  the  cellular  tissue 
layer,  push  the  epithelium  before  them,  and  leave  a  cica- 
trix  where  they  previously  rested.  Viewed  in  this  way, 
granulations  belong  to  the  neoplastic  growths,  as  does  a 
true  granuloma.  Further,  granular  conjunctivitis — ^that 
is,  granulations — may  exist  not  only  on  the  palpebral,  but 
also  on  the  bulbar  conjunctiva,  and  may  extend  even 
to  the  limbus  of  the  cornea ;  while  it  is  well  known  that 
no  papillae  exist  in  these  last  two  locations. 


484 


THE   MEDICAL' RECORD. 


[November  i,  1884. 


It  is  not  to  our  purpose  to  dwell  on  the  different  sub- 
divisions of  granular  conjunctivitis,  as  the  acute,  the 
simple  or  chronic,  and  the  cicatricial,  nor  to  go  further 
than  to  mention  some  of  the  possible  vicious  complica- 
tions, as  e.g,^  contraction  and  bending  of  the  tarsus  ;  dry- 
ness of  the  conjunctiva,  pr  xerosis ;  diseases  of  the  tear- 
passages,  as  stenosis,  stricture,  and  imflammation  of  the 
lachrymal  sac,  e version  of  the  inferior  punctum,  and  ec- 
tropion of  the  inferior  lid ;  changes  in  the  lashes,  as  mal- 
position and  improper  growth ;  and  lastly,  diseases  of 
the  cornea. 

The  secretion  of  granular  conjunctivitis  is  contagious ; 
the  contagion  depending  on  the  secretion  itself,  and  not 
on  the  granulations.  The  secretion  of  the  acute  is  con- 
tagious in  a  higher  degree  than  that  of  the  -chronic  form. 
Arlt  has  stated  that  there  was  a  legitimate  connection 
between  scrofula,  or  tuberculosis,  and  trachoma ;  but  every 
practitioner  knows  that  granular  conjunctivitis  frequently 
develops  in  robust  and  perfectly  healthy  individuals; 
also,  that  impoverished  persons  contract  it  as  well  as 
those  well  fed.  Inhabitants  of  high  altitudes  are  less  liable 
to  its  attack  and  severity  than  dwellers  in  low  and  damp 
districts.  Finally,  granular  conjunctivitis  attacks  individ- 
uals of  ten  to  thirty  years  of  age  most  frequently ;  during 
the  first  and  after  the  forty-fifth  year  an  initial  attack  is 
seldom  observed.  It  is  a  disease  of  the  poor  people,  and 
not  of  those  in  good  circumstances  and  in  the  practice  of 
decent  hygiene. 

As  to  the  therapeutics  of  granular  conjunctivitis,  the 
acute  form  is  best  treated,  from  the  indicative  inflamma- 
tory symptoms,  by  cold  applications,  scarifications,  and 
later  by  astringents  ;  while  the  simple  or  chronic  form  is 
best  treated  by  astringents.  Should  corneal  affections  de- 
velop, as  the  result  of  persistent,  pericorneal  injection, 
in  the  form  of  acute  infiltration  of  the  periphery  of  the 
cornea,  or  as  abscesses,  the  treatment  must  be  limited 
to  atropine,  and  every  kind  of  caustic  be  abandoned.  For 
the  final  stage  of  an  acute  granular  conjunctivitis,  after 
inflammatory  symptoms  have  been  removed  by  cold,  and 
the  serous  infiltration  by  scarifications,  the  best  caustic 
to  be  employed  is  nitrate  of  silver,  in  solution,  one  to 
one  and  a  half  per  cent. ;  but  in  the  chronic  form,  the 
astringent  to  be  relied  upon  beyond  all  others  is  the  sul- 
phate of  copper,  the  copper-stick  or  blue-stone,  as  it  is 
popularly  known.  It  is  enough  merely  to  mention  that 
removal  to  pure,  dry  air,  cleanliness,  freedom  from  dust 
and  smoke,  and,  if  in  a  hospital,  the  limitation  of  pa- 
tients to  the  more  open  and  better  ventilated  parts  of  the 
ward,  must  be  insisted  upon  ;  if,  too,  in  a  hospital,  such 
patients  ought  not  to  be  allowed  to  converse  at  the  bed- 
side of  others  who  have  had  intra-ocular  operations,  such 
as  those  convalescing  from  extraction  of  cataract,  iridecto- 
my, or  paracentesis  ;  nor,  on  the  other  hand,  should  they 
be  allowed  too  close  proximity  to  open  wounds,  erysipe- 
las, pyaemia,  and  puerperal  fever.  The  same  precautions, 
though  in  a  more  emphatic  sense,  should  be  insisted 
upon  with  hospital  patients  under  treatment  for  the  vari- 
ous forms  of  blennorrh5ic  conjunctivitis,  such  as  the 
purulent  ophthalmias  of  the  adult  and  newly-born,  diph- 
theritic conjunctivitis,  etc.  Though  at  the  risk  of  being 
criticised  for  a  digression,  I  take  great  pride  in  noting 
that  for  the  last  four  years  of  operative  work  in  the  oph- 
thalmic wards  of  Charity  Hospital,  not  a  single  operation 
has  been  endangered  by  the  presence  of  trachomatous 
patients ;  and,  as  is  well  known,  granular  conjunctivitis 
abounds  in  the  ophthalmic  division  of  the  hospital,  some- 
times ad  nauseam. 

Neither  the  purpose  nor  the  limit  of  this  paper  will  al- 
low anything  more  than  a  reference  to  the  cicatricial 
stage  of  granular  conjunctivitis  ;  it  is  properly  a  stage  of 
contraction  and  distortion  of  the  tarsal  ligament  and  lid, 
or  a  stage  of  deformity,  and  for  which  treatment  is 
chiefly  surgical.  The  operations  for  blepharophimosis, 
as  canthoplasty,  cantholysis,  etc.,  the  different  proced- 
ures for  the  relief  of  ectropion  of  the  lid,  eversion  of 
the  punctum,  reposition  of  the  cilia,  trichiasis,  and  dis- 


tichiasis,  as  also  for  stenosis  of  the  tear-sac,  stricture, 
etc,  can  here  be  merely  alluded  to.  They  are  operations 
naturally  relegated  to  the  specialist,  some  of  which  be- 
long to  the  nice  calculations  of  cosmetic  surgery. 

e,  BlenncrrhUc  conjunctivitis. — It  is  characterized  by 
the  generation  of  a  well-marked  purulent  secretion  from  a 
highly  vascularized  membrane,  infiltrated  with  serum,  and 
covered  with  granulations.     The  secretion   is  its  chief 
differentiating  factor.     There  are  two  varieties  of  blen- 
norrhoea — ^acute   and  chronic.     An  acute  blennorrhoea 
is  usually  binocular  (double-sided).     It  first  shows  itself 
in  reddened  and  partially  swollen  lids.    The  swelling  can 
involve  a  part  or  the  whole  of  the  lid — can  extend  to  the 
bridge  of  the  nose,  and  may  be  of  such  amount  that  the 
upper  lid  can  be  raised  with  difficulty,  and  the  palpebral 
slit  be  seen  scarcely  at  alL     A  smoky,  thinly  fluid,  copi- 
ous secretion  begins  early  to  course  from  the  palpebral 
opening,  capable  of  being  drawn  out  in  elastic  threads. 
So  strongly  injected  is  the  conjunctiva,  both  palpebral 
and  bulbar,  that  frequent  apoplexies  result ;  the  injection 
and  infiltration  may  extend  up  to  the  cornea,  even  over- 
hang   it,   and    limit    its    diameter;    this    condition  of 
strangulation  of  conjunctival  vessels  is  called  ^A^www, 
and  on  eversion  of  the  lids  a  thick  welt  of  bluish-red 
tumor  is  seen  between  them.     So  soon  as  this  glistening, 
distended  mucous  membrane  is  exposed  to  the  air,  the 
thin  exudation  is  quickly  followed  by  a  new  discharge. 
A  burning  heat  with  severe  pain  in  the  eyes  and  brows 
accompany  the  inability  to  open  the  eyelids,  while  the 
crypts  between  and  underneath  the  false  folds  of  con- 
junctiva are  choked  with  a  rich  exudation  of  a  highly  con- 
tagious, purulent  discharge.     Subsidence  of  infiltration 
takes  place  in  a  few  days ;  the  secretion  diminishes  in 
quantity,  but  becomes  more  consistent,  and  wells  up  like 
a  whitish-yellow  cream.     After  continuing  from  two  to 
three  weeks  the  inflammatory  symptoms  begin  to  disap- 
pear, the  lids  can  be  more  easily  opened,  the  secretion 
becomes  more  mucous,  the  injection,  infiltration,  and 
granulations  subside  graduatim,  and  in  from  six  to  eight 
weeks  the  main  elements  of  this  special  disease  have  dis- 
appeared.    This  long-continued  pressure  on  the  (ante- 
rior) ciliary  arteries  tends  to  impair  the  integrity  of  the 
cornea,  and  to  produce  secondary  affections  of  that  tis- 
sue.    There  may  follow   this   stasis   either  superficial 
ulcerations  at  the  periphery,  or  deep  pus-d6pdts  in  any 
part  of  the  cornea,  with  abscess  and  perforation,  iris-pro- 
lapse, traumatic  iritis,  etc. 

Chronic  blennorrhoea  differs  in  the  degree  of  primary 
inflammatory  symptoms,  the  secretion  is  more  riiuco- 
purulent  in  character,  and  easily  dries  on  the  lashes. 
More  than  in  the  acute  form,  granulations  develop,  and 
ultimately  may  lead  to  shrinkage  of  tarsus  and  ectropion. 
The  chief  anatomical  changes  m  blennorrhoea  consist  of 
the  thickening  of  the  stroma  of  the  conjunctiva,  the  dis- 
tention of  the  vessels,  and  the  thickening  of  their  adven- 
titia.  A  simple  conjunctival  catarrh  may  eventuate  in  a 
blennorrhoea;  a  conjunctivitis,  not  originally  catarrhal, 
may  eventuate  in  a  blennorrhoea ;  as,  for  instance,  an 
acute  granular  conjunctivitis,  or  a  croupous  or  diphthe- 
ritic form.  In  fact,  a  true  diphtheria  of  the  conjunctiva, 
while  itself  rare,  usually  ultimates  in  a  blennorrhoea. 

The  most  common  cause  of  a  blennorrhoic  conjuncti- 
vitis is  the  conveyance  of  a  similar  secretion  from  any 
mucous  membrane,  either  of  the  patient  or  of  another 
person,  and  that  mucous  membrane  may  be  conjunctival, 
vaginal,  or  urethral.  This  contagion  may  be  conveyed 
by  actual  contact,  or  by  transmission  through  the  air. 
Further,  the  daughter-conjunctivitis  will  not  necessarily 
be  the  same  as  the  mother-conjunctivitis. 

The  management  of  blennorrhoea  must  be  conducted 
on  two  lines :  i,  protection ;  2,  therapeusis.  It  is  of 
the  highest  importance  that,  in  case  the  affection  is  of  one 
eye,  the  other  should  have  a  protective  bandage ;  that  in 
every  case  the  greatest  precaution  should  be  taken 
against  the  possibility  of  a  conveyance  of  discharge  to 
the  attendants.     Towels,  sponges,  and  compresses  should 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


485 


never  be  twice  U3ed  without  thorough  cleansing  and  dis- 
infection, and  applicating  cloths  should  be  burned. 
Treatment  proper  should  be  guided  by  the  phase  of  the 
process,  by  the  character  of  the  mucous  membrane  and 
the  secretion,  and  by  the  corneal  implication,  if  any  be 
present.  The  following  general  rules  should  be  fol- 
lowed: I.  If  the.  mucous  membrane  be  smooth  and 
shin/}  and  covered  with  a  thin  and  transparent  or  slightly 
cloudy  exudation,  or  if  there  be  a  thin  and  fluid  secre- 
tion of  a  gray  or  light  yellow  color,  cold  applications 
roust  be  used,  while  caustics  must  be  avoided.  2.  If  the 
tissues  are  swollen  or  chemotic,  scarifications  must  be 
made,  followed  by  cold  applications.  3.  If  granulations — 
that  is,  papillary  bodies  in  folds — have  developed,  if  the 
lid-swelling  has  begun  to  subside,  if  there  be  not  a  thin, 
glairy  exudation,  but,  on  the  contrary,  a  thick  yellow- 
homogeneous  secretion,  then  caustics  are  indicated.  4, 
If  the  cornea  be  involved  in  the  last  picture  of  granula- 
tions and  discharge,  then  caustics  are  indicated,  because 
so  long  as  they  successfully  fulfil  their  indication  the 
progress  of  corneal  disease  is  abated. 

There  is,  perhaps,  no  conjunctival  disease  in  which  the 
caustic  treatment  meets  with  such  eminent  success  as 
attends  its  adoption  in  proper  time  and  strength  in  blen- 
norrh6ic  conjunctivitis.     It  is  a  fundamental  principle 
that  the  strength  of  the  caustic  must  be  proportioned  to 
the  intensity  and  development  of  the  inflammatory  pro- 
cesses ;  at  the  same  time  the  caustic  must  be  used  at  the 
beginning  weaker  than  the  grade  of  the  inflaimmation 
would  indicate,  and  may  be  strengthened  little  by  little 
as  the  mucous  membrane  shows  a  tolerance.     In  this 
regard  is  shown  the  judgment  of  the  practitioner,  to  pre- 
serve the  balance  of  power,  so  to  speak,  on  the  side  of 
the  disease  and  not  on  that  of  the  caustic,  as  it  is  always 
easier  to  increase  the  strength  of  the  latter,  if  required, 
than  to  combat  the  injudicious  effect  of  a  too  powerful 
caustic.     Among  the  possible  bad  effects  of  too  powerful 
astringent  treatment  is  the  destruction  of  the  corneal  epi- 
thelium, perhaps  already  undermined  by  the  blennorrhoic 
processes.    Solutions  should  average  of  the  strength  of  one 
to  two  per  cent.     Corneal  disturbances,  as  simple  or  ne- 
crotic keratitis,  abscess,  or  keratitis  profunda,  are  to  be 
treated  with  atropine,  one-half  to  one  per  cent ;  as  cor- 
neal involvements  are  usually  sequels  of  the  acute  in- 
flammatory stage,  caustics  will  have  been  resorted  to,  and 
their  use  may  be  continued,  but  with  care. 

In  this  category  belongs  the  blennorrhoea  of  the  newly- 
bom,  of  which  but  little  need  be  said,  as  it  is  easily  recog- 
nized by  the  character  of  the  discharges  and  its  appearance 
in  two  or  three  days  after  birth.  It  is  a  strange  statement, 
and  to  some  may  be  new,  that  not  every  case  of  blennor- 
rhoea of  the  infant  is  developed  from  a  blennorrhoea  of  the 
vagina  of  the  mother ;  but  without  doubt  the  majority 
of  the  cases  do  so  develop.  1  have  treated  many  cases 
of  blennorrhoea,  beginning  within  forty-eight  hours  of 
birth  from  no  traceable  cause,  in  which  at  no  time  was 
there  a  discharge  greater  than  what  might  occur  in  a 
mild  catarrhal  conjunctivitis,  and  which  came  to  good 
recovery  in  a  few  days  under  mild  caustic  treatment 
and  cleanliness.  In  the  blennorrhoea  of  the  newly-born, 
as  in  that  of  adults,  the  same  question  arises  as  re- 
gards the  continuance  of  the  caustic  treatment  during 
corneal  complication,  such  as  keratitis  profunda,  abscess, 
etc.;  it  may  be  emphasized  on  the  part  of  infantile 
blennorrhoea,  that  such  treatment  is  not  only  not  con- 
tra^indicated,  but,  on  the  other  hand,  may  be  pursued  with 
advantage.  The  surgical  measures  necessary  in  abscess 
of  the  cornea,  as  puncture,  and  removal  of  a  prolapsed 
iris,  win  only  be  mentioned  here. 

The  forms  of  conjunctivitis  known  under  the  generic 
heads  of  croupous  and  diphtheritic  need  not  claim  our 
attention ;  they  are  rare,  even  in  a  large  special  prac- 
tice, are  not  necessarily  coincident  with  croup  or  diph- 
theria of  the  air-passages,  and  do  not  indicate  caustics 
as  an  essential  element  in  treatment  Caustics,  how- 
ever, are   to  be  used  after  the  pseudo-membrane  has  I 


been  removed,  and  the   process  becomes  a  secondary 
blennorrhoea. 

The  last  variety  of  conjunctivitis  to  claim  our  notice 
at  this  time  is  the 

/.  Phlyctenular. — It  is  introduced  here  by  way  of 
negative  argument  as  to  caustics  ;  that  is  to  say,  they 
are  not  to  be  used  in  any  stage.  A  brief  summary 
of  its  characteristics  should  be  given.  One  of  the 
most  common  of  all  ophthalmias,  and  chiefly  among 
children  before  their  fifteenth  year,  it  is  begotten  in 
scrofula,  bad  hygiene,  or  poor  living ;  it  is  limited  to  a 
small  portion  of  the  bulbar  conjunctiva  between  the  cor- 
neal periphery  and  the  cul-de-sac ;  it  is  known  by  its 
pimple  or  bladder-like  prominences,  which  may  be  single 
or  multiple ;  the  phlyctens  or  swellings  may  become  ab- 
scess-like, and  may  form — to  use  an  anomalous  expression 
— an  elevated  ulcer.  The  disease  has  a  peculiar  tendency 
to  extend  itself  in  the  form  of  phlyctens  upon  the  cor- 
nea, even  to  the  centre  of  its  face.  Patients  with  phlyc- 
tenular conjunctivitis  have  such  scrofulous  exhibits  as 
the  following :  eczematous  and  impetiginous  eruptions 
in  the  vicinity  of  the  lids,  at  the  nasal  angles,  on  the  up- 
per lip,  behind  the  ears,  and  on  the  hairy  portions  of  the 
body;  glandular  swellings,  other  mucous  catarrhs,  etc. 
Phlyctenular  conjunctivitis  is  not  contagious,  as  are  the 
diseases  already  described.  Frequently  no  abnormal  se- 
cretion attends  it ;  on  the  other  hand,  it  is  to  be  noted 
that  the  phlyctenular  form  is  a  frequent  sequel  of  other 
diseases  in  other  parts  of  the  organ — such  as  blepharitis 
in  scrofulous  subjects,  disturbances  of  the  tear-passages, 
episcleritis,  etc. 

The  treatment  in  brief  follows  these  lines  :  i .  Iron 
and  cod-liver  oil ;  a  proper  diet  and  hygiene  to  combat 
any  possible  scrofula  and  the  tendency  to  blood-impov- 
erishment, of  which  this  disease  is  an  index.  2.  Irrita- 
tion by  csdomel,  and  by  ointments  of  the  red  or  yellow 
mercurial  oxide  placed  within  the  lids.  3.  The  avoid- 
ance of  all  derivatives  and  depressants.  4.  The  contin- 
uance of  topical  remedies  long  after  all  inflammatory 
changes  have  passed  away.  For  the  photophobia,  always 
present,  and  which  in  children  is  known  by  the  peculiar 
manner  in  which  they  blink  at  you  from  under  the  bent 
arm,  the  sovereign  remedy  is  ducking  the  face  in  cold 
water. 

Finally,  in  connection  with  the  treatment  of  mucous 
membranes  by  the  silver-nitrate,  it  should  be  noted  that 
the  excessive  use  of  this  salt  produces  a  discoloration 
called  argyrosis^  or  a  silvering  of  the  papillae  of  the  co- 
rium.  While  this  is  a  frequent  result  of  the  internal  use 
of  silver,  as  for  epilepsy,  chorea,  etc.,  it  is  quite  rare  as 
due  to  topical  application.  Professor  Neumann,  of  Vi- 
enna, once  showed  the  author  of  this  paper  a  section  of 
the  lower  lid  in  a  condition  of  argyrosis,  which  in  a 
bright  light  gave  the  beautiful  lustre  of  veins  of  silver 
where  the  papillae  of  the  corium  were  discolored  by  the 
silver-nitrate. 

•  S3  West  Fiftibth  Street. 


Eczema  and  Trophic  Centres. — Dr.  F.  A.  Groat,  of 
Fremont,  O.,  writes ;  "  In  an  article  in  The  Medical 
Record  of  March  15th  the  question  is  asked,  'Is  conges- 
tion of  the  trophic  skin-centres  the  cause  of  eczema  ?  * 
Since  reading  that  article  I  have  met  with  a  case  of  vesic- 
ular eczema  which  seemed  to  be  peculiar,  in.  that  it  was 
developed  only  over  the  superficial  muscles  of  both  hands 
supplied  by  the  ulnar  nerve;  making  its  appearance 
with  the  advent  of  warm  weather,  for  six  consecutive 
years,  only  upon  these  muscles,  and  never  having  been 
benefited  by  treatment,  local  or  internal,  alone  or  in 
combination.  The  man  was  unusually  well  developed 
physically,  with  no  apparent  indication  of  disease,  unless 
obesity  be  pathological,  and  no  local  cause  for  the  erup- 
tion to  be  found.  If  from  congestion  of  the  nerve-centre, 
would  it  manifest  itself  only  in  muscles  supplied  by  ter- 
minal branches  of  the  nerve  ?'' 


486 


THE  MEDICAL   RECORD. 


[November  i,  1884. 


THE  LAWS  OF   DISSECTION. 
By  henry  a.  RILEY,  Esq., 

NBW  YOKX.    2  J 

The  laws  of  most  of  the  United  States,  and  of  England 
as  well,  provide  for  the  lawful  dissection  of  human  bodies 
in  the  interests  of  medical  science.  These  laws  are,  most 
of  them,  of  recent  origin,  although  the  first  enactment  in 
England  was  passed  as  early  as  1540,  in  the  time  of 
Henry  VIII.  It  was  then  declared  that  the  Masters  of 
the  Mystery  of  Barbers  and  Surgeons  might  take  each 
year  four  persons  executed  for  felony,  for  anatomies,  and 
to  make  incision  of  the  same  dead  bodies,  or  otherwise 
to  order  the  same  after  their  dissections  at  their  pleasure, 
for  their  further  insight  and  better  knowledge,  instruction 
insight,  learning  and  experience  in  the  science  or  faculty 
of  surgery. 

In  1565  Queen  Elizabeth  allowed  the  College  of 
Physicians  similar  privilege  of  dissecting  annually  four 
felons.  In  1752  George  II.  permitted  the  bodies  of  all 
murderers  executed  in  London  and  Westminster  to  be 
delivered  to  the  surgeons  for  anatomical  purposes.  Not- 
withstanding these  enactments,  the  supply  of  bodies  for 
dissection  was  not  sufficient  for  the  demand,  and  numer- 
ous attempts  were  made  by  grave-robbers  to  meet  the 
wants  of  medical  students.  In  1830,  the  act  known  as 
the  Anatomy  Act  was  passed,  and  it  is  in  pursuance  of 
its  provisions  that  the  medical  profession  in  Great  Brit- 
ain now  secure  material  for  dissection  and  instruction. 
This  act  provides  for  the  licensing  of  persons  practising 
anatomy,  and  establishes  inspectors  of  the  various  schools. 
The  principal  section  of  the  act  is  as  follows  :  "  It  shall 
be  lawful  for  any  executor,  or  other  party  having  lawful 
possession  of  the  body  of  any  deceased  person,  and  not 
being  an  undertaker  or  other  party  intrusted  with  the 
body  for  the  purpose  only  of  interment,  to  permit  the 
body  of  such  deceased  person  to  undergo  anatomical  ex- 
amination, unless  to  the  knowledge  of  such  executor  or 
other  party  such  person  shall  have  expressed  his  desire, 
either  in  writing  at  any  time  during  his  life,  or  verbally 
in  the  presence  of  two  or  more  witnesses  during  the  ill- 
ness whereof  he  died,  that  his  body  after  death  might  not 
undergo  such  examination,  or  unless  the  surviving  hus- 
band or  wife  or  any  known  relative  of  the  deceased  per- 
son shall  require  the  body  to  be  interred  without  such 
examination."  This  act  in  its  preamble  declares  that  the 
legal  supply  of  human  bodies  for  such  anatomical  ex- 
amination is  insufficient  fully  to  provide  the  means  of 
such  knowledge,  and  its  effect,  as  stated  by  Justice  Ste- 
phen in  Queen  v.  Price,  L.  R.,  12  Q.  B.  Div.,  247,  has 
been  "  that  the  bodies  of  persons  dying  in  public  institu- 
tions whose  relations  are  unknown  are  so  dissected."  The 
duty  of  properly  interring  the  remains  after  dissection  is 
placed  upon  the  persons  giving  the  bodies  to  the  physi- 
cians. 

In  New  York  the  first  law  on  the  subject  was  passed 
in  1854,  and  it  has  been  amended  by  legislative  enact- 
ments passed  in  1879,  1881,  and  1883.  The  law  as  it 
now  stands  is  clear,  distinct,  and  satisfactory  in  its  work- 
ing. It  is  as  follows  :  **  It  shall  be  lawful  for  the  gover- 
nors, keepers,  wardens,  managers,  and  persons  having 
lawful  control  and  management  of  all  public  hospitals, 
prisons,  alms-houses,  asylums,  morgues,  and  other  public 
receptacles  for  deceased  persons,  to  deliver,  under  the  con- 
ditions hereinafter  mentioned  and  in  proportion  to  the 
number  of  matriculated  students,  the  bodies  of  deceased 
persons  therein,  to  the  professors  and  trustees  in  all  the 
medical  colleges  of  this  State  authorized  by  law  to  confer 
the  degree  of  doctor  of  medicine.  And  it  shall  be  lawful 
for  the  said  professors  and  teachers  to  receive  such 
bodies  and  use  them  for  the  purpose  of  medical  study. 
Medical  colleges  which  desire  to  avail  themselves  of  the 
provisions  of  this  act  shall  notify  said  governors,  keep- 
•ers,  wardens,  and  managers  of  public  hospitals,  peniten- 
tiaries, alms-houses,  asylums,  morgues,  and  other  public 
receptacles  for  the  bodies  of  deceased  persons  in  the 


counties  where  the  colleges  are  situated,  and  in  counties 
adjacent  thereto,  of  such  desire,  and  it  shall  be  obligatory 
upon  said  governors,  keepers,  wardens,  and  managers  to 
notify  the  proper  officer  of  said  medical  colleges  when- 
ever there  are  dead  bodies  in  their  possession  that  come 
under  the  provision  of  this  act,  and  ta  deliver  said  bodies 
to  said  colleges  on  their  application.  Provided,  how- 
ever, that  such  remains  shall  not  have  been  desired  for 
interment  by  any  relative  or  friend  of  such  deceased  per- 
son within  forty-eight  hours  after  death  ;  provided,  sdso, 
that  the  remains  of  no  persons  who  may  be  known  to 
have  relatives  or  friends  shall  be  so  delivered  or  received 
without  the  assent  of  such  relatives  or  friends ;  and  pro- 
vided that  the  remains  of  no  person  detained  for  debt, 
or  as  a  witness,  or  on  suspicion  of  crime,  or  of  any 
traveller,  or  of  any  person  who  shall  have  expressed  a 
desire  in  his  or  her  last  illness  that  his  or  her  body  be  in- 
terred, shall  be  delivered  or  received  as  aforesaid,  but 
shall  be  buried  in  the  usual  manner ;  and  provided,  also, 
that  in  case  the  remains  of  any  person  so  delivered  or 
received  shall  be  subsequently  claimed  by  any  relative 
or  friend,  they  shall  be  given  up  to  said  relative  or  friend 
for  interment ;  and  it  shall  be  the  duty  of  said  professors 
and  teachers  to  dispose  of  said  remains  in  accordance 
with  the  instructions  of  the  Board  of  Health  in  said  locali- 
ties where  such  medical  colleges  are  situated,  after  the 
remains  have  served  the  purpose  of  study  aforesaid.  And 
for  any  neglect  or  violation  of  the  provisions  of  this  act 
the  party  so  neglecting  shall  forfeit  and  pay  a  penalty  of 
not  less  than  twenty-five  nor  more  than  fifty  dollars,  to 
be  sued  for  and  recovered  by  the  health  officer  of  said 
cities  and  places  for  the  benefit  of  their  department" 

The  great  demand  for  bodies  for  dissection  early  out- 
ran the  supply,  as  has  been  stated,  and  the  art  of  the 
resurrectionists  began  to  be  developed.  In  the  year 
1788,  forty-four  years  before  the  passage  of  the  British 
Anatomy  Act,  the  case  of  Rex  v,  Lynn,  2  T.  R.,  733, 
was  tried.  It  was  one  of  the  first  cases  of  the  kind  in 
the  books,  and  puzzled  the  lawyers  very  much,  notwith- 
standing the  fact  that  the  general  subject  of  rights  over 
dead  bodies  had  been  discussed  by  the  text  writers.  In 
that  case  Lynn  was  indicted  for  a  misdemeanor  in  disin- 
terring a  body  for  the  purpose  of  dissection.  It  was 
urged  on  his  behalf  that  the  offence  was  only  cognizable 
in  the  ecclesiastical  courts,  but  the  judges  of  the  King's 
Bench  declared  that  it  was  a  fit  matter  for  a  criminal 
court,  and  said  that  common  decency  required  the  prac- 
tice to  be  stopped,  **  being  highly  indecent  and  cotiira 
bonos  mores,  at  the  bare  idea  alone  of  which  nature  re- 
volted." As  the  judges,  however,  thought  that  Lynn 
might  have  committed  the  act  through  ignorance,  he  was 
only  punished  by  a  fine  of  five  marks.  In  some  later 
cases  the  punishment  was  made  severe,  and  at  the  pres- 
ent rime  there  would  certainly  be  no  leniency  shown  to 
any  one  who  removed  a  body  unlawfully.  In  Regina 
V,  Sharpe,  i  D.  &  B.,  160,  it  was  held  to  be  a  misde- 
meanor to  disinter  a  body  at  all  without  proper  authority, 
even  when  the  motives  for  the  act  were  laudable,  it  ap- 
pearing that  a  son  disinterred  his  mother  in  order  to  bury 
her  in  his  father's  grave  in  consecrated  ground,  but  he 
was  able  to  do  this  only  by  the  use  of  a  false  pretence. 
The  difficulty  which  the  lawyers  had  in  fixing  the  grade 
of  the  offence  came  from  an  inability  to  decide  diat  a 
dead  body  could  be  property  and  the  subject  of  theft 

Willcox,  an  old  writer  upon  the  laws  of  the  medical  pro- 
fession, says  that  the  whole  question  of  the  lawftilncss 
or  unlawfulness  of  taking  bodies  for  dissecrion  depends 
upon  the  answer  to  the  quesrions :  "  Is  it  a  violation  of 
property?  Is  it  a  personal  injury  to  any  individual? 
Or  is  it  an  injury  to  the  public  ?  Every  lawyer  who  has 
mentioned  the  subject  has  admitted  that  there  is  no 
violation  of  property  in  respect  to  the  corpse  itself,  wliich 
is  necessary  to  constitute  the  removal  an  offence ;  and 
Blackstone  has  distinctly  stated  that  the  only  property 
violated  is  the  grass  and  soil  of  the  land  wherein  the  body 
was  interred,  in  respect  to  which  the  person  may  bring 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


487 


his  action  of  trespass,  but  the  law  has  not  provided  any 
punishment  as  for  an  offence.  It  is  equally  clear  that  it 
is  not  an  injury  to  any  person ;  for  the  shrewd  lawyers  of 
Coke's  time  determined  that  the  body  was  no  person, 
but  a  lump  of  clay  ;  and  the  only  injury  which  can  give 
a  right  of  action  to  that,  which  amounts  to  a  violation  of 
any  legal  right  of  a  relative  or  master,  is  such  as  may  be 
said  to  recoil  upon  him  by  causing  him  expense,  labor, 
or  loss  of  valuable  service."  The  theory  of  the  early 
cases,  such  as  that  of  Lynn,  seems  to  be  that  the  offence 
is  one  against  the  public,  but  this  opinion  is  not  now 
maintained  against  the  abstract  question  of  the  use  of 
bodies  for  dissection.  It  is  no  longer  considered  that 
any  offence  is  committed  against  the  person,  against  the 
public,  or  against  property  m  dissecting  the  human  body, 
provided  this  be  done  decently,  for  scientific  or  medical 
purposes,  and  in  the  mode  prescribed  by  law.  In  the 
recent  well-known  case  of  Queen  v.  Price,  decided  by 
Justice  Stephen,  in  Wales,  no  later  than  February,  1884, 
where  it  was  held  that  cremation  was  a  legal  mode  of 
disposing  of  the  bodies  of  the  dead,  this  language  is 
used  :  "  The  law  to  be  collected  from  these  authorities 
seems  to  me  to  be  this  :  The  practice  of  anatomy  is  law- 
ful and  useful,  though  it  may  involve  an  unusual  means 
of  disposing  of  dead  bodies,  and  though  it  certainly 
shocks  the  feelings  of  many  persons,  but  to  open  a  grave 
and  disinter  a  dead  body  without  authority  is  a  misde- 
meanor, even  if  it  is  done  for  a  laudable  purpose."  It 
was  claimed  in  this  case  that  the  common  law  gave  the 
right  of  Christian  burial  to  every  person,  and  that  con- 
sequently cremation  was  illegal,  especially  if  not  directed 
by  the  deceased  ;  but  Justice  Stephen  held  that  the  ex^ 
pressions  implying  a  righi  of  burial  were  used  at  a  time 
when  cremation  was  not  conceived  of  as  possible  in 
England,  and  consequently  no  special  importance  is  to 
be  given  to  the  words  touching  the  lawfulness  or  other- 
wise of  cremation.  The  same  argument,  if  valid  against 
cremation,  would  hold  good  in  considering  the  question 
of  dissection,  for  if  Christian  burial  is  a  right  and  duty,  it 
would  prechide  all  use  of  bodies  for  anatomical  purposes. 

Following  the  English  common  law,  the  several  States  of 
this  country  have  united  in  regarding  the  violation  of  tombs 
an  indictable  offence,  and  the  intended  purpose  of  the  rob- 
bery, if  it  is  dissection,  does  not  mitigate  the  criminality 
of  the  act.  In  New  York,  for  instance,  removing  dead 
bodies  for  the  purpose  of  selling  the  same,  or  from  mere 
wantonness,  is  punishable  both  by  fine  and  imprisonment. 

When  the  robbery  of  Mr.  Stewart's  grave  occurred, 
some  years  since,  it  was  thought  by  many  persons  that 
the  law  was  powerless  to  punish  the  scoundrels  if  caught, 
but  there  would  have  been  no  trouble  on  this  point.  It 
is  not  at  all  likely  that  their  object  was  dissection ;  it 
must  have  been  to  obtain  the  reward  for  the  return  of 
the  body  which  they  knew  would  be  offered,  and  this 
would  certainly  come  under  the  provision  of  the  law  for- 
bidding the  removal  of  dead  bodies  for  the  purpose  of 
sale.  In  New  Hampshire  and  Vermont  the  punishment  for 
this  crime  may  consist  of  fines,  whipping,  and  imprisonment. 

Actual  presence  at  the  time  of  the  body-lifting  is  not 
essential  to  a  conviction ;  but  a  person  directing  the  pro- 
ceeding, and  near  enough  to  give  aid  and  assistance  if 
required,  can  be  punished  as  well  as  those  actually  open- 
ing the  grave  (Tate  v.  State,  6  Black,  in). 

The  considerations  thus  far  produced  treat  only  of  the 
criminality  of  grave-robbery ;  some  civil  remedies  for  the 
same  offence  will  be  touched  on  at  a  future  time. 


A  Foreign  View  of  a  New  York  Practice. — A  Ber- 
lin medical  journal  publishes  the  following:  **Dr.  Beach(!), 
one  of  the  first  surgeons  of  New  York  (!),  is  living  here  at 
present.  This  gentleman  has  gained  by  his  practice 
property  to  the  amount  of  $5,000,000  (!).  We  are  of 
the  opinion,"  adds  the  editor,  "  that  it  is  the  specialists 
who  are  in  the  best  way  to  accomplish  these  material  re- 
sults." It  may  be  asked  if  the  above  paragraph  is  not 
part  of  a  scheme  to  flood  New  York  with  Berlin  specialists. 


PSEUDO-BULBAR   PARALYSIS. 

Bilateral  Apoplexy  of  the  Lenticular  Nuclei, 
Simulating  Lesion  in  the  Floor  of  the  Fourth 
Ventricle. 

By  S.  E.  fuller,  M.D.,  and  WM.  BROWNING,  M.D., 

BXOOKLYN,  N.  Y. 

It  has  not  been  thought  possible  as  yet  to  include  injury 
of  the  lenticular  nuclei  among  the  forms  of  brain  dis- 
ease which  admit  of  approximate  localization.  A  limited 
number  of  cases  have,  however,  accumulated  which  seem 
to  indicate  that  an  insult  to  both  these  nuclei,  and  per^ 
haps  to  only  one,  may  produce  a  picture  of  its  own. 

Since,  however,  these  bodies  are,  from  statistics,  a  very 
frequent  seat  of  apoplexy,  and  besides  entirely  latent 
foci  have  been  found  in  them  at  the  autopsy,  it  is  prob- 
able that  the  special  symptomatology  observed  in  the 
other  cases  may  have  been  caused,  not  by  the  lenticular 
injury  itself,  but  by  an  extension  of  it  or  its  effects  to 
adjacent  parts.  Be  that  as  it  may,  that  injury  of  these 
bodies  may  produce  a  very  well-marked  and  peculiar 
group  of  symptoms  is  shown  by  the  following  case.  It 
occurred  in  the  practice  of  Dr.  Fuller,  and  was  seen  in 
consultation  by  Dr.  McNaughton.  The  interest  of  the 
case  was  fully  recognized  and  pains  were  taken  to  ob* 
serve  all  symptoms.  The  clinical  history  is  furnished  by 
Dr.  Fuller ;  the  results  of  the  autopsy  are  by  Dr.  Browning. 

A  lady,  M.  J ,  aged  sixty-one,  had  suffered  three 

years  previously  a  left  hemiplegia  without  aphasia.  Face» 
throat,  and  neck  muscles  reported  to  have  been  unaf- 
fected. Further  particulars  of  the  immediate  attack  un- 
known. She  recovered  from  it  fully.  Toward  the  end 
of  convalescence  she  came  under  my  (Dr.  Fuller's)  care 
complaining  of  a  severe  burning  sensation  in  the  sole  of 
the  left  foot.  This  was  remedied  with  ergot  and  bromides. 
There  were  no  premonitions  to  the  present  attack.  It 
came  on  about  4  p.m.,  July  16,  1884,  while  in  the  bath^ 
room.  She  is  said  to  have  called  out  to  a  lady  in  the 
next  room,  saying  she  was  very  dizzy  and  had  pain  in  her 
head,  the  lady  helped  her  to  bed.  There  seemed  to  have 
been  no  loss  of  consciousness  on  the  patient's  part 

Upon  my  arrival  she  was  speechless,  and  remained  so. 
It  was  only  possible  for  her  to  make  an  expiratory  guttural 
sound.  Having  been  paralyzed  before,  she  immediately 
proceeded  to  show  me  that  it  was  not  the  same  by  raising 
first  the  right  arm  and  leg  and  then  the  left.  The  lips, 
tongue,  and  muscles  of  deglutition  were  paralyzed ;  the  sa- 
liva flowed  from  whichever  angle  of  the  mouth  was  lower- 
most ;  the  upper  portion  of  the  facial  nerve  was  function- 
ally intact  and  the  pupils  reacted  normally.  She  could 
not  open  her  jaws,  or  only  to  the  slightest  extent  The 
lower  jaw  could  be  readily  depressed  with  the  finger,  but 
on  attempting  to  swab  out  collecting  mucus  from  the  oral 
cavity  and  throat — as  was  often  necessary — the  jaws 
would  close  and  press  on  whatever  had  been  introduced 
into  the  mouth,  despite  the  strongest  desire  of  the  patient 
to  keep  them  open.  The  nurse  had  to  be  instructed, 
before  cleansing  the  mouth,  to  wrap  a  blade  in  soft 
material  and  place  it  edgeways,  so  as  to  keep  the  jaws 
apart  until  the  little  procedure  was  finished.  This  symp- 
tom persisted  during  the  conscious  life  of  the  patient  The 
tongue  was  quite  motionless.  The  urine  had  been  exano- 
ined  some  time  previously,  and  found  free  from  albumen. 

Immediately  subsequent  to  this  attack'  there  was  an 
enormously  increased  flow  of  urine.  In  the  first  three 
hours  she  passed  water  three  times.  Though  not  meas- 
ured, it  was  estimated  by  the  attendants  to  have  been  a 
quart  each  time.  In  this  urine  there  was  about  twenty 
vol.  per  cent  of  albumen  and  once  a  trace  of  sugar  with 
Fehling's  test  Withm  twenty-four  hours  the  quantity  of 
urine  returned  to  normal.  Albumen  persisted  in  it  for  a 
time  at  least.  She  snored  very  loudly  after  the  attack, 
though  not  doing  so  previously.  There  was  no  trouble 
from  the  soft  palate  when  awake,  although  it  hung  in  a 
paralyzed  condition. 

So  long  as  she  remained  conscious,  1.^.,  for  the  first 


488 


THE  MEDICAL  RECORD. 


[November  i,  1884. 


five  days,  she  always  gave  notice  of  desire  to  defecate  or 
urinate — no  incontinence  whatever.  During  the  same 
period  she  would  often  motion  for  spectacles,  paper,  and 
pencil,  indicating  that  the  latter  be  first  moistened  in  the 
mouth.  She  would  then  communicate  by  writing  her 
questions,  and  showed  the  full  possession  of  her  mental 
faculties.  This  was  farther  shown  by  her  remembering 
when  medicine  was  due  (given  per  rectum  and  hy|)0* 
dermically),  by  directing  attention  when  a  sample  of  urine 
had  been  forgotten,  and  in  a  variety  of  other  ways,  ^.^., 
curiosity  as  to  the  nature  and  cause  of  her  own  condition. 
Sh*  would,  however,  cry  rather  easily,  the  tears  then 
running  silently  down  over  the  cheeks.  This  could 
hardly  be  wondered  at,  or  considered  as  loss  of  control 
over  the  feelings. 

It  is  very  doubtful  if  she  succeeded  in  swallowing  any- 
thing, though  she  tried  hard  to  do  so.  She  was  success- 
fully nourished  with  peptonized  milk,  etc.,  per  rectum. 
•  The  stemo-cleido  and  other  large  neck-muscles  did 
not  appear  to  be  affected.  The  sense  of  hearing  re- 
mained good,  and,  in  fact,  no  anaesthesia  of  any  part  of 
the  body  was  discovered. 

The  pulse,  respiration,  and  temperature  showed  no  dis- 
tmbance  to  within  forty-eight  hours  of  death.  At  this 
time,  after  some  extra  exertion  on  her  part,  she  gradually 
sank  into  a  stupor.  Some  twelve  hours  before  the  end  she 
became  very  much  flushed  and  hot  to  the  touch  over  the 
whole  body.  This  afterward  gave  place  to  a  kind  of 
collapse.     Death  on  the  morning  of  July  23d. 

Post-mortem  in  the  afternoon,  with  the  assistance  of 
Drs.  Fuller  and  McNaughton.  The  autopsy  being  per- 
mitted only  on  condition  that  nothing  whatever  be  car- 
ried away,  it  was  impossible  to  make  a  minute  examina* 
tion  of  any  of  the  parts,  yet  this  could  not  have  added 
very  materially  to  the  exactness  of  the  present  case. 
Only  the  brain  was  removed,  including  the  cord  to  oppo- 
site the  second  cervical  vertebra. 

The  cerebro-spinal  fluid  was  slightly  increased.  The 
vertebral  and  carotid  arteries  with  their  branches  on  the 
base  of  the  brain  presented  numerous  patches  of  ather- 
oma, but  were,  at  least  in  all  their  larger  divisions,  still 
permeable.  No  farther  abnormal  appearances  on  any 
portion  of  the  surface  of  the  brain. 

The  lateral  ventricles  presented  nothing  unusual,  unless 
some  slight  adhesions  between  the  ependyma  of  the 
ventricular  roof  and  floor.  Laterally  in  the  brain-sub- 
stance, on  the  two  sides  very  nearly  symmetrical,  were  two 
fresh  clots.  •  These  were  in  the  lenticular  nuclei,  extend- 
ing into  all  three  divisions  and  tapering  off  posteriorly. 

On  the  right  side,  in  front  of  and  external  to  the  recent 
hemorrhage,  were  the  remains  of  the  former  one.  This 
was  in  the  claustrum  or  between  daustrum  and  external 
capsule.  It  extended  from  nearly  opposite  the  front  end 
of  the  ventricle  to  about  opposite  the'  front  end  of  the 
recent  hemorrhage,  and  was  consequently  just  beneath 
the  Island  of  Reil.  There  was  simply  an  oblong  space 
remaining,  with  slightly  separated  walls  enclosing  a  little 
brownish,  thick  fluid  matter.  The  said  walls  consisted  of 
somewhat  thickened  and  discolored  tissue  without  any 
smooth  interior  surface.  Such  is,  according  to  Charcot, 
the  usual  form  and  appearance  of  old  extravasations  at 
this  point.  This  had  clearly  caused  the  former  left 
hemiplegia.  Motor  fibres  are  not  known  to  traverse  this 
tract.  The  paralysis  must,  therefore,  have  been  caused 
by  pressure  transmitted  from  the  clot,  a  view  which  is 
corroborated  by  her  recovery. 

As  to  the  recent  extravasations,  the  same  general  de- 
scription will  apply  to  both.  Each  was  in  amount  equal, 
perhaps,  to  a  pigeon's  egg.  The  nerve-tissue  was  not 
only  much  torn,  but,  from  the  size  of  the  clot  and  its 
longitudinal  form,  also  forced  apart.  The  two  were 
from  their  appearance  of  about  the  same  date.  It  was 
not  possible  in  either  of  them  to  distinguish  any  older  or 
newer  portion.  They  were  very  dark,  in  part  semi-fluid, 
and,  so  far  as  color  and  character  of  the  clot  went,  at 
least  one  or  two  days  old,  perhaps  several. 


The  head  of  each  clot  was  about  opposite  the  front  end 
of  the  thalamus,  and  diminished  backward  to  nearly  op- 
posite the  posterior  end  of  the  same.  The  main  ix)rtion 
appeared  to  be  wholly  in  the  lenticular  nucleus,  while  its 
posterior  prolongation  or  branches  may  have  encroached 
to  a  limited  extent  on  other  structures. 

No  further  foci  were  found  in  any  part  of  the  brain. 
The  medulla  oblongata,  pons,  etc.,  presented  no  morbid 
appearance.  Sections  through  these  parts  were  made 
very  close  together,  so  that  even  a  pin-head  clot  could 
not  have  escaped  notice.  An  embolus  or  thrombus  of  a 
week's  standing  must  have  produced  visible  softening,  so 
that  they  also  can  be  excluded. 

The  recent  apoplectic  centres  were  so  large  and  the 
tissue  about  them  was  so  torn  as  to  render  them  value- 
less for  the  localization  of  any  single  symptom.  The  in- 
terest of  the  case,  however,  lies  in  the  peculiar  combina- 
tion of  symptoms.  These  presented  a  complex  believed 
to  indicate  lesion  in  a  part  that  at  the  autopsy  was  found 
intact.  To  recall  some  of  them  :  the  paralysis  was  bi- 
lateral, quite  symmetrical  as  regards  both  extent  and 
severity,  and  occurred  on  the  two  sides  simultaneously. 
There  was  no  loss  of  consciousness.  Immediately  there 
was  a  greatly  increased  flow  of  urine,  and  which  contained 
both  albumen  and  sugar.  There  was  also  well-marked 
labio-glosso-pharyngeal  paralysis.  This  forms  a  group 
of  symptoms  the  cause  of  which  is  generally  assigned  to 
trouble  at  the  base  of  the  fourth  ventricle.*  Thrombosis 
or  embolism  of  a  terminal  bulbar  artery  is  credited  with 
almost  identical  consequences,  and  apoplexy  from  one  of 
the  same  vessels  may  not  appear  very  different. 
**  A  limited  number  of  cases  presenting  varying  degrees 
of  similarity  to  the  present  one  have  been  brought  to- 
gether by  Ross  in  his  recent  work  on  *^  Diseases  of  the 
Nervous  System."  '  From  these  he  concludes  that  de- 
struction of  the  lenticular  nuclei  in  whole  or  in  part  may 
produce  nearly,  if  not  quite,  all  the  symptoms  of  lesion 
of  the  medulla  oblongata.  The  cases  described  or  ab- 
stracted by  him,  however,  ran  a  slower  course,  and  were 
less  typical  of  acute  bulbar  trouble.  Ross,  in  one  place, 
calls  this  form  pseudo-bulbar  paralysis — a  convenient 
term  for  the  present.  To  explain  this  grouping  of  symp- 
toms, he  points  out  that  the  lenticular  injury  must  affect 
fibres  in  their  course,  probably  through  the  internal  cap- 
sule, from  the  psychomotor  centres  in  the  brain-cortex  to 
the  nerve-centres  in  the  medulla.  He  notes  that  con- 
sciousness may  not  be  lost  at  the  occurrence  of  this  acci- 
dent, but  does  not  in  any  of  his  cases  mention  disturbance 
in  the  urinary  secretion.  Wernicke  mentions  the  occur- 
rence of  bulbar  symptoms  in  cerebral  disease.  He  even 
cites  a  case  of  so-called  pseudo-bulbar  paralysis,  where, 
however,  the  pathological  condition  varied  materially 
from  that  under  consideration.  In  the  present  case  the 
two  hemorrhages  must  have  occurred  at  the  same  time. 
Although  not  into  a  part  vitally  so  important  as  the 
medulla,  yet  from  their  size  and  after-effects  they  proved 
fatal. 

Experimental  destruction  of  one  or  both  these  nuclei 
has  not  established  any  facts  available  in  localization. 
Ferrier,  together  with  many  neurologists,  simply  believes 
that  hemiplegia  may  result  from  such  injury  when  unilat- 
eral. But  these  cases,  while  not  disproving,  certainly  do 
not  confirm  this. 

As  to  the  possibility  of  distinguishing  between  these  two 
(the  lenticular  and  the  bulbar)forms,  some  points  may  be 
noticed.  In  the  present  case  there  were  no  convulsions ; 
no  ]>aralysis  below  the  throat ;  nothing  unusual  in  pulse  or 
respiration  ;  evidently  no  trouble  with  the  sense  of  hear- 
ing, but  increased  reflex  excitability  of  the  nmscles  oi 

1  In  Brain  for  July,  1884,  T.  D.  Mann  describes  what  he  calls  a  case  cfpuntpo- 
plcctk  bulbar  paralysis,  liie  symptoms  ver)'  closely  resembled  those  in  our  own 
case.  He  writes  :  "  llierc  is  not  much  difficulty  in  localizing  a  lesion  such  as  this. 
The  symptoms  at  once  point  to  the  posterior  part  of  the  rhomboid  sinus."  Aa  sa- 
topsy  would  show  whether  such  complacent  confidence  in  his  power  of  localixaooo 
were  warranted. 

*  Vol.  ii..  pp.  696-8  of  first  edition,  continued  in  the  second  editioo.  Farther 
two  cases  of  depou  in  lenticular  nuclei— one  unilateral— «re  given  by  Ross,  in 
Brain  for  July,  1883. 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


489 


the  jaw.  In  bulbar  lesions  the  corresponding  reflexes  are, 
on  the  contrary,  lowered,  while  the  other  symptoms,  here 
absent,  occur  with  more  or  less  frequency. 

Such  and  similar  points  of  discrimination  would,  how- 
ever, in  view  of  the  very  limited  number  of  known  cases 
from  which  to  draw  conclusions,  hardly  warrant  con- 
fidence in  an  attempt  at  differential  diagnosis. 


HYDROCHLORATE  OF  COCAINE  AS  A  LOCAL 

AN/ESTHETIC   IN   GYNECOLOGY. 

By  W.  M.  polk,  M.D., 

NSW  YORK. 

As  a  matter  of  some  interest,  just  at  this  time,  I  give  the 
results  obtained  with  hydrochlorate  of  cocaine  in  two 
cases  of  trachelorrhaphy  done  this  afternoon  (October  29, 
1884). 

Case  I.  Double  laceration  of  the  cervix  uteri,  ex- 
tending on  both  sides  to  cervico-vaginal  junction, — The 
vagina  was  first  washed  with  a  warm  water  douche,  then 
the  cervix,  the  patulous  cervical  canal,  and  the  vaginal 
walls  adjoining  the  cervix  were  carefully  washed  with 
Castile  soap,  this  in  turn  was  washed  off,  and  the  surface 
carefully  dried.  Next  a  four  per  cent,  solution  was 
painted  over  the  cervix,  in  the  canal,  and  over  the  ad- 
jacent vaginal  wall  with  a  cameVs-hair  brush.  This  was 
repeated  twice,  at  intervals  of  two  to  three  minutes,  mak- 
ing three  applications  of  the  drug.  Within  three  minutes 
of  the  last  application  the  operation  was  begun. 

It  required  the  removal  of  extensive  pieces  of  cicatricial 
tissue  from  each  angle,  making  it  an  elaborate  operation 
of  its  kind.  The  time  consumed  was  about  forty  minutes, 
the  patient  made  no  complaint  and  suffered  no  pain  till 
the  last  ten  minutes  of  the  procedure,  then  she  spoke  of 
her  discomfort  as  being  a  sense  of  soreness  rather  than 
acute  pain. 

Thinking  that  the  case  might  be  one  of  those  in  which 
the  normal  sensitiveness  of  the  region  was  not  great, 
consequently  one  that  might  have  borne  the  operation 
without  the  use  of  any  anaesthetic,  local  or  general,  I 
chose  a  second. 

Case  II. — The  woman  was  one  having  less  self-con- 
trol than  the  first,  and  with  a  good  deal  of  normal  sensi- 
tiveness about  the  uterus  and  vagina.  The  preparation 
of  the  region  and  the  application  of  the  anaesthetic  was 
the  same  as  in  Case  I. 

i^o  pain  was  felt  till  the  lapse  of  about  twenty  minutes, 
then  it  was  so  acute  as  to  require  an  application  of  the 
solution  of  cocaine,  making  in  her  the  fourth.  In  three 
minutes  the  operation  was  continued  and  soon  completed 
without  further  pain.  This  last  application  was  made 
directly  to  the  cut  surfaces,  first  freeing  them  from  blood. 

The  patient,  who  three  years  ago  had  had  the  same 
operation  performed  under  ether,  was  asked  which  method 
she  preferred,  that  with  ether  or  this  last  without ;  she 
promptly  replied,  this  last. 

In  the  first  case  the  effect  of  the  drug  seemed  to  be, 
that  it  not  only  blunted  sensibility,  but  it  appeared  to 
retard  the  first  appearance  of  blood  upon  the  cut  surface. 

These  cases  I  offer  as  a  contribution  to  the  solution  of 
the  question  now  so  prominently  before  the  profession — 
the  place  to  be  held  by  hydrochlorate  of  cocaine  as  a  local 
anaesthetic.  With  a  view  of  testing  its  value  in  obstetric 
practice  a  series  of  observations  are  being  made  in  the 
Emergency  Hospital,  the  solution  being  applied  to  the 
cervix  and  upper  part  of  the  vagina  during  the  severe 
pains  of  the  first  stage  of  labor.  The  result  I  beg  leave 
to  communicate  to  you  when  the  number  of  cases  are 
large  enough  to  make  the  report  valuable. 


,v 


PODERMOCLYSis  is  the  name  given  to  the  process 
o{  \Tu\^ci\T\g  saline  solutions  subcutaneously.  It  has 
been  eni ployed  in  Naples  in  the  algid  stage  of  cholera, 
and  witl?^^  some  success. 


Hernia  of  the  Lung. — Dr.  Mariani  reports  in  the 
Revista  de  Medicina  y  Cirurgia  Prdcticas  the  case  of 
a  man,  forty-five  years  of  age,  of  good  general  health,  in 
whom  nothing  abnormal  was  discoverable  when  he  was 
resting  quietly.  But  when  he  was  exercising  actively  or 
coughmg,  a  globular  swelling  appeared  in  the  right  su- 
pra-clavicular region,  varying  in  size  with  each  respira- 
tory movement.  During  an  attack  of  violent  coughing 
it  would  grow  to  such  a  size  as  to  pass  entirely  across 
the  front  part  of  the  neck,  attaining  a  volume  equal  to 
that  of  the  head.  Upon  the  cessation  of  the  provoking 
cause,  the  neck  would  return  to  its  normal  dimensions. 
This  phenomenon  was  first  noticed  when  the  patient  was 
fourteen  years  of  age.  The  diagnosis  was  made  by  Dr. 
Bellida  of  a  conical  hernia  of  the  lung. 

Dilatation  of  the  Stomach  in  Children. — In  an 
article  with  this  title  in  the  Archives  Gdnhrales  de  Mede- 
cine  of  August  and  September,  1884,  Dr.  J.  Comby  asserts 
that  the  affection  is  one  of  by  no  means  rare  occurrence 
in  young  children,  and  he  cites  in  proof  of  his  assertion 
upward  of  fifty  cases  seen  by  him  in  dispensary  practice.. 
Dilatation  of  the  stomach,  he  says,  is  constantly  associated 
with  rachitis,  and  this  is  not  a  chance  occurrence,  but  the 
relation  between  the  two  conditions  is  one  of  cause  and 
effect.  The  digestive  troubles  precede  and  prepare  the 
way  for  rickets,  but  are  themselves  the  result  of  improper 
alimentation.  The  physical  signs  of  gastric  ectasis  are  a 
prominent  belly,  tympanism,  and  the  succussion  sound. 
The  functional  troubles  accompanying  this  condition  are 
manifold.  There  may  be  dyspepsia,  convulsions,  in- 
somnia, urticaria,  eczema,  bronchitis,  etc.,  any  one  alone 
or  several  occurring  together.  The  prognosis  is  serious, 
because  the  dilatation  may  persist  up  to  the  period  of 
adolescence  or  even  into  adult  life.  The  sole  cause  of 
this  affection  is  the  improper  feeding  of  infants ;  the  little 
patients  are  brought  up  on  the  bottle,  given  solid  food 
prematurely,  or  weaned  at  an  early  period.  But  the  dis- 
ease may  also  occur  in  infants  at  the  breast,  who  are 
nursed  too  much  or  too  frequently.  The  prophylaxis 
consists  in  nursing  at  the  breast  and  in  restricting  the 
periods  of  suckling  within  reasonable  limits.  Weaning 
should  not  be  begun  too  soon,  and  should  be  accom- 
panied very  gradually.  When  dilatation  exists  the  diet 
should  be  strictly  confined  to  milk  for  infants  and  dry 
food  for  children  of  a  more  advanced  age.  Sometimes 
washing  out  of  the  stomach  is  necessary. 

Aural  Thermometry. — Dr.  Flitner  {St,  Petersburger 
Dissertation)  has  instituted  a  series  of  measurements  of 
the  temperature  of  the  meatus  auditorius,  both  in  health 
and  in  acute  and  chronic  ear  affections.  The  measure- 
ments were  taken  by  means  of  a  specially  adapted  ther- 
mometer. The  average  temperature  of  the  meatus  was 
found  to  be  in  health  98.4°  F.,  the  averages  for  the  axilla 
and  rectum  being  at  the  same  time  about  99°  F.  The 
author's  general  conclusions  are  :  i.  Daily  measurements 
of  the  temperature  in  the  course  of  inflammations  of  the 
ear  show  that  the  temperature  ofthe  latter  stands  in  a 
constant  regular  connection  with  the  general  tempera- 
ture of  the  body.  Therefore,  in  ear  affections,  the  local 
measurements  not  only  may  be.  substituted  for,  but  even 
must  be  preferred  to  measurements  of  the  temperature  in 
the  rectum  and  axilla.  2.  The  same  may  be  asserted  in 
regard  to  ear  affections  complicated  with  pneumonia, 
erysipelas,  and  other  diseases.  3.  In  cases  of  ear  affec- 
tions complicated  with  morbid  processes  in  the  cranial 
cavitj',  or  even  on  the  surface  of  the  skull  (caries,  phle- 
bitis of  the  sinuses,  er}'sipelas),  the  temperature  in  the 
meatus  sometimes  stands  higher  than  in  the  rectum. 
Hence  the  measurements  in  the  ear  canal  give  us  a 
clearer  indication  as  to  the  course  of  morbid  process  in 
the  head  than  the  rectal  measurements,  and  are  prefer- 
able to  the  latter  beyond  any  comparison. 


490 


THE  MEDICAL  RECORD. 


[November  i,  1884. 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 

New  Yorky  November  i,  1884. 
CURIOSITIES  OF  MEDICAL   ADVERTISING. 

•'  Nay  we  see  the  weakness  and  credulity  of  men  is  such,  as  they 
will  often  prefer  a  mountebank  or  witch  before  a  learned  physician." 

—Lord  Bacon. 

We  have  been  furnished  with  some  instructive  facts  re- 
garding the  extent  and  character  of  the  quack  advertise- 
ments which  form  so  picturesque  a  feature  in  the  daily 
papers  of  our  country.  We  refer  now  only  to  the  per- 
sonal advertisements  of  learned  gentlemen  who  an- 
nounce "advice  free/'  "  no  cure  no  pay,"  *' twenty  years* 
Prussian  hospital  experience,"  and  similar  appeals  to  the 
business  instinct  and  personal  confidence  of  the  com- 
munity. The  American  press  furnishes  a  rich  field  for 
the  study  of  this  kind  of  literature,  a  study  which  is  by 
no  means  without  profit,  since  advertising  columns,  after 
all,  reflect  the  wants  of  the  people.  Give  us  the  medical 
advertisements  of  a  nation  and  we  can  get  no  inconsid- 
erable insight  into  its  character. 

One  of  the  first  things  which  strikes  the  mind  in  peru- 
sing the  modest  announcements  of  professional  skill  set 
forth  in  the  daily  press  is  the  aptness  and  vigor  of  the 
literary  style.  Here  for  example  is  a  whole  story  in 
three  words:  "Dr.  A.  W.  X.,  pile  specialist,  Indian- 
apolis ; "  again,  "  Dr.  Tool,  removes  worms  with  agree- 
able remedies,  Philadelphia."  With  more  circumlocu- 
tion a  Dr.  N.  B.  announces,  "  after  years  of  prac- 
tice" that  "married  ladies,  although  apparently  healthy 
and  not  blessed  with  offspring,  can  receive  a  medicine 
that  is  pleasant,  safe,  and  certain  to  crown  their  hopes. 
Let  no  false  modesty  prevent  your  calling."  Per  con- 
tra, another  announcement  informs  the  lady  readers  of 
the  precious  press  with  a  suggestive  brevity  that  "  our 
pennyroyal  pills  are  as  good  as  gold." 

It  is  not  always  in  simple  language,  however,  that  the 
specialists  of  the  secular  and  religious  papers  present 
their  claims.  Assurances  of  skill  and  experience,  guar- 
antees of  success,  sympathetic  appeals  to  sufferers  from, 
alas  !  "  Our  National  Weakness  "  (which  we  had  always 
thought  was  tea)  all  these  are  put  forth  with  gorgeous 
rhetorical  embellishments.  We  might  here  express  the 
wonder  how  it  is  that  the  East  Indian  missionary,  who 
«  supplies  a  simple  vegetable  formula"  for  cancer,  con- 
sumption, and  erring  but  noble  young  men,  continues  to 
hold  out  so  long ;  and  why  it  is  that  "  twenty  years'  ex- 
perience in  a  Prussian  hospital "  is  the  necessary  qualifi- 
cation for  the  treatment  (by  mail)  of  amour  blesse. 

We  desire  to  do  no  violence  to  the  feelings  of  our  West- 


ern colleagues,  but  the  hard  fact  exists  that  the  medical 
advertiser  flourishes  with  an  ever-increasing  exuberance 
as  we  go  toward  the  setting  sun.  He  also  develops  an 
originality  of  expression  and  fertility  of  adjective  which  is 
hardly  known  in  the  South  or  East. 

From  Jackson,  Michigan,  there  comes  a  two  column 
ejaculation  of  the  merits  of  a  local  doctor  beginning: 
"Earthquake!  Earthquake!  Earthquake!"  ...  "I 
will  treat  on  the  weekly  instalment  plan.  ...  I  can 
treat  the  mother,  I  can  treat  the  father,  I  can  treat  the 
daughter!  ...  I  will  make  you  a  Good  Reliable 
Family  Physician  ! "  for  twenty-five  cents  a  week. 

There  is  a  place  in  Idaho  known  as  Boise  City.  Two 
columns  or  thereabouts  of  its  local  paper  are  devoted  to 
the  advertisements  of  cock-sure  specialists,  and  private 
dispensaries,  where  the  erring  young  and  the  prematurely 
old  are  guaranteed  a  cure.  If  it  is  true  that  Boise  City 
is  but  a  sample  of  other  Western  towns  we  can  only  con- 
clude that  the  amount  of  '*  manhood  "  lost  or  mislaid  in 
the  territories  is  appalling. 

It  appears  to  be  the  custom  of  these  advertising  spe- 
cialists to  make  their  homes  in  the  great  cities  and  then 
placard  the  columns  of  provincial  newspapers  with  their 
advertisements.  San  Francisco,  St.  Louis,  Denver,  Chica- 
go, New  York,  Philadelphia,  and  Boston  are  all  more  or 
less  supplied  with  these  creatures,  San  Francisco  heading 
the  list. 

Another  custom  which  is  growing  rapidly  in  the  West 
is  that  of  establishing  private  dispensaries  for  the  cure 
of  all  forms  of  ailment.  The  Oxygen  Cure  Company 
and  the  Galenic  Institute  of  Minnesota,  the  Li-po-tai 
Chinese  Sanitarium  of  San  Francisco,  the  Medical 
and  Surgical  Infirmaries  in  Nebraska,  Wisconsin,  and 
Colorado  are  specimens  of  this  form  of  enterprise.  A 
somewhat  cursory  examination  among  the  papers  of  a 
dozen  Western  cities  shows  that  all  are  supplied  with 
from  one  to  five  advertising  "  private  dispensaries.** 
Omaha  is  blessed  with  three,  and  San  Francisco  with 
five. 

Men  and  women  apply  to  advertising  quacks,  first, 
because  they  ignorantly  believe  in  their  pretensions  j.^j' 
second,  because  they  have  sotne  disease  which  they  do 
not  wish  to  disclose  to  their  family  physician  or  a  respect- 
able medical  man  ;  and  lastly,  quacks  are  a  final  resort 
of  chronic  invalidism  or  fatal  disease.  The  quacks  them- 
selves advertise  to  treat  and  cure  those  diseases  into 
whose  therapeutics  the  element  of  imagination  largely  ; 
enters.  '*  Chronic  nervous  diseases,"  sexual  disorders, 
syphilis,  all  these  furnish  a  fruitful  field  for  presumptuous 
ignorance  to  work  upon.  Among  over  fifty  quack  ad- 
vertisements nearly  forty  appeal  to  the  classes  above 
mentioned.  For  the  rest,  it  seems  that  piles  and  fistulas, 
cancer  and  consumption,  varicocele,  rheumatism,  and 
gout  are  paying  specialties.  In  a  certain  section  of  the 
West  a  Dr.  C,  "after  twenty  years'  practice  in  Utah," 
"  will  visit  Southern  settlements,  treating  club-foot,  hare- 
lip, etc."  From  which  it  appears  that  Utah  has  advan- 
tages for  the  training  of  orthopoedic  specialists  not  here- 
tofore generally  known. 

There  is  some  tendency  to  make  homoeopathy  a  basis 
of  trade.  A  doctor  in  Austin,  Texas,  announces  himself 
as  a  homoeopath,  and  adds,  with  a  slight  degree  of  ortho- 
graphical inadequacy,  that  he  makes  "  difficult  and  chronic 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


49^ 


diseases  a  specialty.''  He  is  less  liberal  than  a  certain 
"s|>ecialist  of  New  York  City,"  temporarily  residing 
among  the  Mormons,  whose  methods  of  treatment  are 
stated  with  an  absolute  absence  of  bias,  to  be  "  Homoeo- 
pathic, eclectic,  electricity,  and  magnetism ;  cures  guaran- 
teed by  maiV  which,  we  would  add,  is  by  far  the  safest 
way  to  guarantee  them. 

It  must  not  be  inferred  that  the  East  or  South  is  en- 
tirely free  from  the  obnoxious  advertisements  of  the  kind 
we  are  describing.  New  York,  while  it  has  not  many  of 
the  typical  advertising  specialists,  is  particularly  rich  in 
<*  magnetic  healers,"  'Vitalizing  rubbers,"  and  doctresses 
who  "take  confinements  at  the  house."  Throughout 
New  England  the  practice  is  gaining  of  a  doctor  pub- 
lishing his  card,  often  with  some  slight  recommendation, 

such  as  "graduate  of ,"  "four  years*  city  experience," 

etc.,  appended.  By  this  means  good  physicians  some- 
times get  in  bad  company.  Thus  the  card  of  a  Hartford 
physician  comes  out  sandwiched  between  that  of  a  clair- 
voyant and  a  chronic  disease  specialist.  Certain  parts 
of  New  England  are  victimized  by  itinerant  quacks,  who 
enter  a  town,  buy  up  the  local  editor,  and  fleece  the 
hypochondriacs  and  incurables  annually. 

We  cannot  close  without  referring  to  an  advertisement 
which  recently  appeared  in  the  Philadelphia  Ledger. 
The  capacity  shown  therein  for  exact  and  clear-cut  defi- 
nition of  the  author's  wants  and  talents  is  quite  unique. 
A  physician,  graduate  of  Jefferson  Medical  College  (Class 
of?),  '*  whose  religious  character  is  above  reproach  wants 
a  cash  salary  ...  in  a  wealthy  sickly  family.  War- 
rants to  treat  successfully  dropsy,  consumption,  cancer," 
etc.  A  cash  salary  in  a  wealthy  sickly  family  is  a  great 
desideratum,  and  it  is  unfortunate  that  society  is  so  ar- 
ranged that  wealthy  families  as  a  rule  refuse  to  be  sickly ; 
while  sickly  families  as  a  rule  are  bound  to  be  poor. 

It  would  be  a  mistake  to  infer  from  the  facts  and  com- 
ments given  above,  that  the  practice  of  advertising  in  the 
secular  press  is  at  all  common  among  the  profession  in 
this  country.  On  the  contrary,  we  have  been  surprised 
and  pleased  to  find  that  among  the  seventy  thousand 
V  doctors  in  this  country  where  advertising  is  a  national 
institution,  so  few  comparatively  indulge  in  it.  That  the 
practice  is  sortiewhat  increasing,  however,  cannot  be 
denied.  And  we  fear  that  the  license  given  by  a  wrong 
interpretation  of  good  ethical  rules,  to  distribute  profes- 
sional and  "  practice  limited  "  cards  ad  libitum  is  doing 
something  to  increase  this  tendency. 


THE  MEDICAL  VALUE  OF  THE   COFFEE  ALKALOID 
AND  ITS  ALLIES. 

There  is  one  element  of  uncertainty  in  medical  practice 
which  doctors  ought  to  eliminate^  and  that  is  the  use  of 
impure  drugs.  No  one  has  done  greater  service  to  the 
profession  in  this  line  than  Dr.  £.  R.  Squibb,  and  it  has 
again  to  thank  him  for  calling  in  question  the  utility  of 
certain  preparations  which  have  of  late  years  been  flood- 
ing the  market,  viz.,  those  of  coca  and  guarana.  Dr. 
Squibb  states  emphatically  that  no  good,  fresh,  carefully 
prepared  specimens  of  coca  are  obtainable.  He  also 
says  that  the  specimens  of  guarana,  which  is  not  a  pure 
article  but  a  South  American  secret  mixture,  are  also 
untrustworthy,  unequal,  and  expensive.     He  has,  there- 


fore, decided  to  abandon  the  preparation  of  these  articles 
and  to  substitute  fluid  extracts  of  tea  and  of  green  coffee 
in  their  place. 

It  is  known  that  the  active  principles  caffeine,  theinei 
and  guaranine  are  chemically  and  physiologically  identical^ 

From  certain  tests  Dr.  Squibb  concludes  that,  in  thq 
power  of  keeping  ofif  drowsiness  and  producing  a  sensQ 
of  restfulness,  the  following  were  the  equivalents  : 

Three  grains  of  artificial  caffeine  =180  grains  of  coca^ 
or  45  grains  of  cocaine  ;  three  grains  of  artificial  caffeine 
=  70  grains  of  tea,  containing  2  grains  of  theine ;  three 
grains  of  artificial  caffeine  =  60  grains  of  guarana,  coa-* 
taining  2.6  grains  of  guaranine  ;  three  grains  of  artificial 
caflfeine  =  160  grains  of  coflfee,  containing  1.95  grain 
of  caffeine. 

According  to  this  the  cocaine  alkaloid  is  the  strongest^ 
next  comes  the  coffee  alkaloid,  then  that  of  the  tea  and 
of  guarana.  The  differences  between  the  last  three, 
however,  are  slight  and  might  easily  be  accounted  for,, 
without  having  to  assume  any  physiological  difference  in 
the  alkaloids. 

The  conclusion  arrived  at  by  Dr.  Squibb  is  that  we- 
can  dispense  entirely  with  coca  and  guarana  in  medicine, 
and  can  use  instead  officinal  preparations  of  tea  and 
coffee  or  the  alkaloid  caffeine.  Fluid  extracts  are  pre- 
ferred, because  in  this  way  the  dosage  can  be  more  ac- 
curately adjusted. 

Dr.  Squibb*  s  views  and  conclusions  merit  the  atten- 
tion of  the  profession,  but  they  are  open  to  criticism  in 
two  directions.  In  offering  the  tea  and  coffee  extracts 
as  substitutes  for  coca,  guarana,  and  in  a  measure,  caf- 
feine, he  based  his  inferences  as  to  equivalence  mainly 
upon  a  series  of  experiments  upon  a  single  symptom, 
drowsiness,  in  a  single,  individual.  Furthermore,  it  is  to 
be  inferred  that  cocaine  and  caffeine  are  identical  alka-^ 
loids.  This  is  not  the  case.  The  chemical  formulae  for 
the  two  are  different,  and  physiological  experiments,  sa 
far  as  they  have  been  carried,  also  show  some  differences 
in  action. 

The  claim  that  tea  and  coffee  extracts  will  do  all  that 
coca  and  guarana  will  is  a  plausible  one,  and  it  is  impor-^ 
tant  that  it  should  be  definitely  established  or  refuted.  We 
trust  that  further  careful  experiment  will  be  made.  Mean* 
while  we  remind  our  readers  of  the  very  truthful  words  of 
Rossbach :  "  The  medicinal  use  of  caffeine  is  very 
limited." 

A  NEW  BISMUTH-TEST  FOR  SUGAR. 
The  Trommer  test  for  sugar  is,  as  all  urologists  are^ 
aware,  inexact  and  difficult  in  many  cases  on  account  of 
various  substances  which  react  with  the  solution,  as  cre- 
atinine and  uric  acid,  and  also  because  creatinine  and 
other  substances  retain  the  cupric  oxide  in  solution.  In 
order  to  avoid  these  difficulties  it  has  been  attempted  ta 
replace  the  solution  by  the  reduction  of  subnitrate  of 
bismuth  in  the  presence  of  an  alkaline  liquid.  To  this, 
end  Almen  has  used  a  solution  of  2  grms.  of  subnitrate  of 
bismuth,  4  grms.  of  tartrate  of  potassium  and  sodium,  and 
100  grms.  of  a  solution  of  caustic  potash  ;  and  with  this 
he  has  succeeded  in  detecting  o.  i  of  sugar  in  100  grms.  of 
the  liquid. 

After  a  good  deal  of  experimentation  on  this  subject, 
Nylander,  in  a  recent  paper  in  the  Zeiischrift  fUr  phys^ 


492 


THE   MEDICAL  RECORD. 


[November  i,  1884. 


iologische  Chemiey  advises  a  solution  containing  2  grms.  of 
subnitrate  of  bismuth,  4  grms.  of  the  tartrate  of  potassium 
and  sodium,  and  100  grms.  of  caustic  alkaline  lessive  j 
the  undissolved  bismuth  salt  is  separated  by  filtra- 
tion, and  in  order  to  better  determine  the  effect  of  the 
quantity  of  the  caustic  alkali,  he  dissolved  in  the  alkaline 
liquid  3,  6,  7, 1 2,  and  1 7  per  cent,  of  supposed  anhydrous 
caustic  soda.  He  found  that  the  solution  containing  about 
8  per  cent,  of  the  caustic  alkali  was  much  the  most  deli- 
cate, and  that  it  should  be  used  i  part  for  10  of  the  liquid 
to  be  analyzed  ;  also  that  with  this  he  could  easily  detect 
0.04  per  cent,  of  sugar  in  the  urine.  Even  with  0.025 
per  cent,  tlie  reaction  was  not  doubtful. 

It  has  been  objected  to  the  bismuth  solution  that  it  gives 
a  black  precipitate,  but  Nylander  shows  that  this  may  be 
avoided  by  using  not  more  than  8  per  cent,  of  the  alkali 
solution,  the  precipitate  being  caused  by  an  excess  of  it. 
It  does,  however,  cause  a  precipitation  of  phosphates. 
In  examining  one  hundred  specimens  of  urine  fourteen 
were  found,  by  the  bismuth  test,  to  contain  sugar.  These 
fourteen  were  then  examined  by  the  Trommer  and  Worm- 
MOller  methods;  these  showed  sugar  in  twelve  speci- 
mens, the  result  in  the  other  two  being  doubtful,  but  the 
yeast  test  showed  that  these  also  contained  sugar.  The 
presence  of  albumen  in  a  specimen  of  urine  interferes  with 
the  reaction  of  the  bismuth  solution,  but  only  when  it 
exceeds  o.  5  per  cent.  The  presence  of  sugar  is  shown  by 
a  black  or  grayish  tint.  With  this  test,  therefore,  as  with 
others,  it  is  necessary  first  to  free  the  urine  from  albumen. 
A  great  advantage  of  this  solution  is  that  it  keeps  well. 


BRAIN-PRESSURE.  IN   PUBLIC    SCHOOLS. 

Only  a  short  time  ago  certain  English  sanitarians  were 
claiming  that  the  decreased  death»rate  in  Great  Britain 
was  largely  due  to  the  improvement  in  the  modes  of  rear- 
ing and  educating  children.  Now  comes  an  elaborate 
report  made  by  Dr.  Crichton  Brown,  in  which  it  is  con- 
tended that  the  system  of  school  education  in  England, 
is  doing  great  mental  and  physical  damage  to  the  rising 
generations.  He  claims  that  in  some  London  schools 
nearly  one-half  (46  per  cent.)  the  children  suffer  from 
iiabitual  headache,  that  54  per  cent,  suffer  from  neuralgia 
or  toothache,  40  per.  cent,  from  insomnia,  and  that  short- 
sightedness gradually  increases  from  2^  per  cent,  in 
Standard  I.  to  9  per  cent,  in  Standard  VI. 

Dr.  Brown  shows  that  while  in  late  years  the  mortality 
from  hydrocephalus  under  five  years  of  age  has  been 
steadily  falling,  owing  to  improved  sanitary  conditions, 
the  mortality  between  five  to  twenty  years  has  been  stead- 
ily increasing.  He  claims  that  the  cause  of  this  increased 
mortality  is  the  brain-excitement  and  fatigue  associated 
with  the  processes  of  education.  The  increase  in  the 
number  of  suicides,  especially  of  those  under  sixteen 
years  of  age,  and  the  increase  of  insanity  are  referred  to 
as  having  some  connection  with  the  educational  methods. 

The  main  point  which  is  made  against  the  British  sys- 
tem of  elementary  education  is,  that  it  attempts  to  enforce 
the  same  amount  and  kind  of  instruction  upon  children 
who  differ  in  the  greatest  degree  as  to  mental  develop- 
ment and  physical  strength.  The  grade  system,  as  car- 
ried on,  is  a  kind  of  Procrustean  bed,  to  which  youthful 
tninds  must  be  made  to  accommodate  themselves.     Ex- 


aminations, studying  after  school  and  at  home,  are  all 
sources  of  immense  injury  and  evil,  according  to  Dr; 
Brown. 

The  report,  of  which  the  foregoing  are  the  main  feature?, 
13  accompanied  with  a  counter-report  by  one  of  the  offi- 
cers  of  the  Government,  Mr.  Fitch.  This  latter  gentle- 
man vigorously  and  ably  criticises  Dr.  Brown's  facts,  con* 
elusions,  and  methods. 

The  London  medical  press  naturally  supports  the  med- 
ical view  of  the  case,  as  presented  by  the  distinguished 
Superintendent  of  the  West  Riding  Lunatic  Asylum. 

From  this  side  of  the  Atlantic  it  appears  as  if  Dr. 
Brown  had  made  a  very  strong  plea,  but  had  been  rather 
carried  away  by  the  dominance  of  preconceived  convio- 
tions.  This  indeed  is  not  the  first  time  that  he  has  ex- 
hibited  his  capacity  for  emplojdng  tempestuous  argumen- 
tation and  unscientific  method.  It  seems  incredible  that 
in  the  present  case  he  has  not  made  some  mistakes. 
The  code  exacted  by  the  English  school  system  is  lighter 
than  that  of  France,  Germany,  Belgium,  and,  we  believe, 
America.  Yet  we  are  told  that  half  of  the  English  school 
children  have  continual  headaches,  insomnia,  and  neu- 
ralgia! Is  it  brain-pressure  that  does  all  this?  Then 
English  children  must  be  phenomenally  stupid,  since 
there  is  certainly  no  such  condition  in  other  countries. 

The  fact  is,  Dr.  Brown  has  dealt  with  only  half  the 
truth.  He  should  have  said  more  about  the  homes  and 
food  of  the  school  children.  Feed  them,  clothe  them, 
and  house  them  better,  and  the  talk  about  over-pressure 
will  be  very  much  less. 

Not  that  we  deny  the  existence,  to  a  considerable  ex- 
tent, of  the  evils  depicted.  They  are  known  in  this  coun- 
try as  well  as  England,  and  the  "  Procrustean  bed  system 
of  teaching"  has  been  condemned  for  years.  But  reme- 
dies are  expensive.  The  plan  suggested  of  having  med- 
ical inspectors  for  the  schools  is  a  good  one,  so  far  as  it 
goes.  It  has  been  tried  in  France,  and  in  some  parts  of 
this  country,  and  has,  we  believe,  worked  satisfactorily. 


AMERICAN    MODE   OF  USING    IODIDE   OF    POTASSIUM. 

For  over  fifteen  years,  says  Dr.  E.  C.  Seguin,  in  the  Ar- 
chives of  Medicine^  the  practice  of  giving  very  large  doses 
of  potassium  iodide  in  certain  cases  has  been  in  use  in 
a  small  circle  of  New  York  physicians.  By  large  doses  is 
meant  such  as  make  up  a  total  of  two  and  a  half  to  ten 
grammes,  in  twenty-four  hours.  The  cases  where  these 
doses  are  indicated  are  those  of  chronic  or  subacute  ul- 
cerative syphilides  or  of  nervous  syphilis  ;  in  rapidly  ex- 
tending syphilitic  ulcer;  in  extremely  acute  syphilitic 
cranial  pain ;  in  syphilitic  coma  or  stupor ;  in  certain 
cases  of  syphilitic  hemispasm,  monospasm,  or  hemiplegia- 
The  mode  of  administration  is  to  give  the  saturated  solu- 
tion of  potassium  iodide  largely  diluted  in  plain  or  feebly 
alkaline  water.  It  is  usually  given  after  meals,  and  prob- 
ably, as  a  rule,  acts  better  in  this  way.  Dr.  Seguin 
advises  administering  it  before  meals ;  and  un- 
doubtedly sometimes  this  method  is  better.  It  is  one 
which  used  to  be  strongly  recommended  by  older 
teachers,  on  theoretical  grounds.  It  is  sometimes  found, 
we  would  add,  that  the  iodide  can  be  best  taken  in  one 
large  dose  at  night ;  or,  if  the  potassium  salt  causes 
irritability,  the  iodide  of  sodium  may  be  substituted. 


November  i,  1884.] 


THE   MEDICAL  RECORD. 


49a 


It  should  not  be  forgotten  that  in  a  few  cases  the 
patients  cannot  take  these  large  doses,  and  also  that  a 
very  prolonged  use  of  them  is  sure  eventually  to  produce 
an  atonic  state  of  the  gastro-intestinal  musculature. 

Dr.  Seguin  has  quoted  a  long  list  of  authorities  on 
sj-philis,  general  medicine,  and  therai)eutics,  in  order  to 
show  that  the  plan  of  heroic  dosage  here  referred  to 
receives  slight  or  no  adequate  notice  in  text-books.  It 
is  only  in  the  works  of  Loomis,  Bartholow,  and  of  Van 
Buren  and  Keyes,  Bumstead  and  Taylor  in  this  country, 
and  of  Buzzard  abroad,  that  any  recognition  of  it  is 
found. 

The  writer  also  shows  that  the  method  originated  with 
the  late  Dr.  Van  Buren,  of  this  city,  and  became  grad- 
ually adopted  as  the  result  of  practical  experience  by  a 
number  of  New  York  physicians.  It  has  been  taught  by 
Dr.  Wm.  H.  Draper,  by  Dr.  K  W.  Taylor,  and  also  by 
Dr.  Wm.  A.  Hammond,  for  many  years.  It  is  essentially 
an  American,  and  more  essentially  a  New  York,  idea. 
It  is  very  proper  that  attention  has  been  called  to  what 
is  undoubtedly  a  remarkably  efficient  therapeutic  meas- 
ure, and  that  due  credit  has  been  given  to  American 
medicine  for  originating  it. 

Cocaine  Hydrochlorate  as  a  Local  ANiEsxHETic 
IN  Gynecology. — Professor  Polk,  of  this  city,  as  will  be 
seen  by  a  communication  in  the  present  issue,  has  used 
hydrochlorate  of  cocaine  successfully  in  two  operations 
upon  the  cervix  uteri.  The  results  in  these  cases  look 
toward  an  extensive  usefulness  of  the  new  anassthetic 
not  only  in  gynecology  but  in  many  of  the  minor  surgical 
operations. 

The  Profits  of  the  International  Health  Ex- 
hibition.— The  Health  Exhibition  which  was  lately 
closed  in  London  shows  a  profit  of  ^30,000. 

Dr.  Joseph  White,  of  Canajoharie,  N.  Y.,  died  on 
October  27th,  in  the  eighty-fourth  year  of  his  age.  He 
was  one  of  the  oldest  physicians,  and  was  the  oldest 
Mason  in  the  State. 

The  International  Collective  Investigation. — 
The  first  inquiry  which  the  Committee  propose  to  insti- 
tute is  in  regard  to  rachitis,  its  frequency,  and  the  phy- 
sical condition  of  the  district  in  which  it  is  found. 

The  Price  of  Cocaine  Hydrochlorate.  —  The 
first  preparations  of  cocaine  hydrochlorate  used  in  this 
city  were  procured  at  an  expense  of  60  cents  a  grain, 
or  $12  an  ounce  for  a  four  per  cent,  solution.  It  will 
probably  be  soon  about  forty  cents  a  grain.  Its  price, 
from  present  indications,  cannot  become  much  less, 
as  only  0.0 1  to  0.02  per  cent,  of  cocaine  can  be  ex- 
tracted from  the  erythroxylon  coca,  depending  on  the 
quality  of  the  leaves.  The  salt  used  in  Albany  at  Dr. 
Merrill's  college  clinic  cost  $4.20  per  ounce,  or  87^  cents 
a  grain.  On  the  other  hand,  it  may  not  be  generally 
known  that  Merck,  whose  laboratory  prepared  the  first 
used  in  this  city,  has  an  agency  in  New  York,  which  re- 
ceives by  cable  early  word  of  the  exportation  of  special 
drags,  and  that  a  considerable  quantity  is  now  under  way 
to  New  York.    At  the  principal  druggists  here  the  demand 


Mortality 
percent. 


has  far  exceeded  the  supply.  It  is  to  be  hoped  that  the 
new  importation  will  bring  the  drug  within  easy  reach  of 
all.  It  had  been  used  on  the  continent  in  throat  clinics 
several  months  before  its  introduction  into  ophthalmic 
practice  by  Dr.  Koller,  which  was  at  the  annual  Oph- 
thalmological  Congress  in  Heidelberg,  September  15th. 
We  learn  from  a  professional  friend,  living  in  our  vicinity, 
that  he  had  used  it  in  a  case  of  paraesthesia  of  the  larynx 
of  an  exceedingly  nervous  lady  some  weeks  before  the 
publication  of  Dr.  Noyes'  letter  in  The  Medical 
Record. 

Another  War  over  Listerism  and  Ovariotomy. 
— A  lively  discussion  is  threatened  between  Mr.  Lawson 
Tait  and  Mr.  Knowsley  Thornton  upon  the  question  of 
the  value  of  Listerism  in  ovariotomy.  Mr.  Thornton  has 
published  a  letter  {American  Journal  of  Obstetrics)^  in 
which  he  tries  to  show  that  his  own  records  of  Listerian 
ovariotomies  are  better  than  those  of  either  Bantock  or 
Tait,  who  do  not  use  Listerism.  The  following  tables 
are  interesting : 

Cases.     Died. 

Thornton,  non-antiseptic  hospital  ovariot- 
omies      33  S  .15.15 

Bantoclc,  non-antiseptic  hospital  ,  ovariot- 
omies       36  8  22.2a 

Thornton,  "Listerian''  hospital  ovariot- 
omies     129         15  ii*62 

Bantock,  *^  Listerian "  hospital  ovarioto- 
mies     113         16  14.15 

Tait's  "  strictly  Listerian,"  on  his  state- 
ment       so  3  6 

Non-antiseptic 176         24  13.95 

It  is  known  that  Mr.  Tait,  when  still  a  rising  ovariot- 
omist,  was  hardly  treated  with  fairness  by  the  London 
gentlemen  whom  he  now  in  his  triumph  too  rancorously 
assails. 

The  Decline  of  Antipvresis. — At  the  meeting  of 
the  German  Society  of  Naturalists  and  Physicians  in 
September  last.  Professor  Ebstein,  of  Gottingen,  read  a 
paper  upon  the  treatment  of  typhoid  fever,  based  on  the 
treatment  of  235  cases  in  the  past  seven  and  a  half 
years.  The  mortality  was  5.5  per  cent.,  or  excluding 
cases  where  treatment  had  not  been  applied,  2.5  per 
cent.  Professor  Ebstein  denied  the  value  of  the  abor* 
tive  calomel  treatment.  He  had  used  careful  dietetic 
and  symptomatic  treatment.  Baths  and  antipyretic 
medicines  were  only  to  be  used  when  the  high  prolonged 
temperature  was  evidently  causing  bad  symptoms.  The 
routine  use  of  these  measures  was  not  advised.  Pro- 
fessor Ebstein' s  views  were  supported  by  most  of  the 
speakers  in  the  discussion  which  followed. 

The  Recognition  of  Hard  Preliminary  Work.— 
Apropos  of  this  matter,  which  we  discussed  in  our  editorial 
columns  recently,  is  a  letter  from  a  correspondent  of  the 
College  and  Clinical  Record^  who  says  :  **  Men  who  have 
worked  their  way  through  a  good  medical  school,  and 
passed  the  ordeal  of  spiking  the  masked  battery  they 
were  compelled  to  charge  at  the  end  of  their  collegiate 
course,  feel  that  they  have  learned  something  substantial, 
and  that  their  diplomas  are  the  certificates  to  this  effect 
made  by  illustrious  men.  Every  honest  worker  feels 
this ;  and  even  though  he  know  enough  to  know  how 
little  he  knows,  yet  he  feels  that  his  diploma  is  worth 
more  than  that  of  a  man  who  graduated  at  the  '  College 
of  Physicians  and  Surgeons  of  Brown's  Cross  Roads, 
Western  Arizona.'     It  is  true,  a  good  diploma  does  not 


494 


THE   MEDICAL   RECORD. 


[November  i,  igg^ 


/  make  a  good  doctor,  but  it  immensely  increases  the 
chances  in  this  direction,  and  diplomas  do  have  a  varying 
commercial  value  !  "  A  self-protection,  the  writer  adds, 
trill  drive  all  graduates  of  first-class  colleges  to  the 
plan  of  indicating  their  alma  mater  after  the  letters 
M.D. 

The  correspondent  from  whom  we  quote  is  right,  so 
far  as  he  goes.  As  is  natural  witli  young  graduates,  he 
attaches  a  rather  exclusive  importance  to  the  value  of 
his  alma  mater,  and  forgets  that  other  things  than  two  or 
three  years  at  a  medical  college  are  required  to  make  a 
doctor.  The  degree  of  A.B.  or  A.M.,  the  year  or  more 
in  a  hospital,  the  post-graduate  study  abroad  or  at  home, 
may,  any  one  of  them,  more  than  compensate  for  didac- 
tic disadvantages. 

The  Use  of  Cocaine  Hydrochlorate  by  Dr.  E. 
S.  Peck,  of  New  York. — Dr.  Peck  writes  :  "  Of  the  three 
uses  of  the  drug — one  physiological,  two  clinical — at  my 
hands,  only  one  deserves  special  mention  at  this  time, 
while  all  corroborate  its  anaesthetic  properties.  A  laborer 
received  a  clean  wound  of  the  lower  lid,  cutting  through 
the  conjunctiva,  tarsal  margin,  and  integument.  A 
stitch  in  the  conjunctiva  and  two  in  the  integument  of 
the  lid  were  taken  after  six  instillations  of  a  four  per 
cent,  solution,  covering  twenty-five  minutes.  Patient 
experienced  no  pain  either  from  the  forceps  or  needles, 
and  stated  that  the  sensation  was  as  if  something  had 
been  pressed  against  the  parts  involved." 

The  Shady  Side  of  Medical  Education  Abroad. — 
The  New  York  Medical  Journal  discusses  in  a  forcible 
and  suggestive  manner  certain  of  the  dangers  to  which 
students  who  go  abroad  to  study  for  medical  instruction 
are  subjected.  **  We  have  no  hesitation  in  asserting,"  says 
Ih^  Journal^  ^' that  many  a  medical  student  who  would 
have  made  a  steady  and  honorable  member  of  his  profes- 
sion, had  he  entered  upon  his  duties  at  once  on  leaving 
college  or  hospital,  has  been  spoiled  by  his  residence 
abroad,  where  he  has  broadened  his  professional  knowl- 
edge but  suffered  an  irreparable  loss  of  moral  tone,  in 
delicacy  of  feeling,  and  in  tenderness  toward  sufifering. 
This  is  no  cant — it  is  simply  an  every-day  experience. 
It  is  unnecessary  to  urge  the  trite  remark  that  an  edu- 
cated physician  is  something  more  than  an  encyclopaedia 
of  facts  or  an  infallible  diagnostician,  that  he  is  or  should 
be  an  honorable  gentleman,  and  that,  too,  not  for  utili- 
tarian reasons,  but  because  it  is  in  him.  .  .  .  The 
*  free  and  easy '  moral  atmosphere  of  the  great  con- 
tinental capitals,  notably  Vienna,  the  light  regard  in 
which  woman  is  held,  the  perfect  subjection  in  which 
patients  are  kept,  and  the  cold-blooded  way  in  which 
those  patients  are  treated — all  of  these  are  dangerous  ele- 
ments in  foreign  medical  education.  .  .  .  Again, 
methods  of  examination  and  treating  patients  are  learned 
which  it  would  be  positive  professional  suicide  for  a  man 
to  practise  at  home."  There  is  more  in  this  same  line 
given  by  our  esteemed  contemporary,  who  does  not  at 
all  deny  at  the  same  time  that  great  benefit  may  be  ob- 
tained by  foreign  study.  We  commend  the  remarks  to 
those  of  our  readers  who  contemplate  studying  abroad 
or  sending  their  sons  there.  It  is  true  that  the  profession 
has  now  more  need  of  honorable  gentlemen  than  of 
*^  soulless  scientists  "  in  its  ranks. 


The  Paris  Academie  de  Medicine  has  talked  cholera 
all  summer  and  has  got  no  further  on  the  matter  than 
when  it  started.  Upon  great  occasions  this  learned  body 
seems  always  to  turn  itself  into  a  Cave  of  the  Winds. 

Dr.  Mills  succeeds  Dr.  Osier  as  Professor  of  Physi. 
ology  in  the  McGill  Medical  College,  Montreal 

Poisoning  from  Mother  Winslow*s  Soothing  Syr\jp, 
— Dr.  A.  B.  Hirsh  reported  to  the  Philadelphia  County 
Medical  Society  the  case  of  a  boy,  aged  twenty  momhs, 
who  was  poisoned  by  "Mother  Winslow's  Soothing 
Syrup."  He  was  given  four  doses  of  less  than  half  a  tea- 
spoonful  in  fourteen  hours.  Vigorous  anti-narcotic  treat- 
ment alone  saved  the  child.  Many  physicians,  we  believe, 
are  familiar  with  similar  cases. 

American  Academy  of  Medicine. — At  the  annual 
meeting  of  the  American  Academy  of  Medicine,  held  this 
week  in  Baltimore,  the  following  officers  were  elected : 
President— A\\>^ri  L.  Gihon,  United  States  Navy ;  Vice- 
Fresidenis^^.  Stansbury  Sutton,  of  Pittsburg,  Pa.; 
James  A.  Steward,  of  Baltimore,  Md.;  William  Elmer,  of 
Bridgeton,  N.  J.,  and  James  Cheston  Morris,  of  Phila- 
delphia, Pa. ;  Secretary  and  Treasurer — Richard  J. 
Dunglison,  of  Philadelphia,  Pa.,  and  Charles  Mclntyre, 
Jr.,  of  Easton,  Pa.,  Assistant, 

Dr.  Oliver  Wendell  Holmes,  of  Boston,  and  Major 
George  M.  Sternberg,  M.D.,  of  the  U.  S.  Army,  were 
elected  honorary  members.  The  following  resolution 
was  unanimously  adopted  : 

"  That  the  American  Academy  of  Medicine  recognizes 
in  the  recent  munificent  gift  of  William  H.  Vanderbilt  to 
the  College  of  Physicians  and  Surgeons  of  New  York,  a 
most  important  and  valuable  service  to  the  science  of 
medicine  in  America ;  that  in  this  spirit  the  Academy 
tenders  to  Mr.  Vanderbilt  its  obligations,  with  the  assur- 
ance that  in  no  better  way  could  the  higher  education  of 
our  profession  and  the  benefit  of  humanity  be  promoted." 

%tmzyxi&  atid  Notices. 

The  Alpine  Winter  Cure.     With  Notes  on  Davos 
Platz,  Wiesen,  St.  Moritz,  and  the  Maloja.     By  A.  T. 
Tucker  Wise,  M.D.,  L.R.C.P.,  M.R.C.S.     London: 
Baillidre,  Tindall  &  Cox.     1884. 
Dr.  Wi^e  has  made  a  special  study  of  certain  mountain 
health-stations,  and,  writing  without  bias  or  exaggeration 
of  any  kind,  what  he  says  may  be  accepted  as  true  with-       , 
out   hesitancy.      The   remarkable  curative  and  health- 
giving  properties  of  the  Alpine  climate  are  abundantly       1 
shown  in  this  unpretentious  little  volume.  I 

Practical  Manual  of  Obstetrics.     By  E.  Verrier, 
M.D.,  Lecturer  on  Obstetrics  in  the  Faculty  of  Medi- 
cine of  Paris.     Fourth   Edition,   with  the  Four  Ob- 
stetric Tables  of  Professor  Pajot ;  One  Hundred  and 
Five  Illustrations.     First  American  Edition,  with  Re- 
vision and  Annotations  by  Edward  L.  Partridge, 
M.D.,  Professor  of  Obstetrics  in  the  New  York  Posl- 
Graduate  Medical  School.     Wood's  Library  of  Med- 
ical Authors.     New  York  :  W.  Wood  &  Co.     1B84. 
This  is  a  brief  risumi  of  practical  obstetrics,  more  par- 
ticularly from  the  French  point  of  view.     It  has  been  in 
a  measure  Americanized  by  the  incorporation  of  more  or 
less  important  notes  supplied  by  Dr.  Partridge.    In  its 
new  shape  it  will  be  found  serviceable  by  students  and 
those  practitioners  who  lack  time  for  the  study  of  certain 
details,  which  are  necessarily  found    in  the  more  pre- 
tentious and  elaborate  treatises. 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


495 


Students'  Manual  of  ELEcrRo-THERAPEurics.  By 
R.  W.  Amidon,  A.M.,  M.D.  New  York :  G.  P.  Put- 
nam's Sons.  1 884* 
This  modest  little  volume  can  in  no  way  replace,  nor 
does  it  pretend  to,  the  more  elaborate  treatises  on  medi- 
<:al  electricity  already  extant.  But  as  an  introduction  to 
practical  electro-therapeutics  this  book  has  its  raison 
atre.  Its  chief  merit  consists  in  the  fact  that  it  is  quite 
concise,  and,  as  far  as  it  goes,  thoroughly  scientific  Static 
electricity  is  not  dignified  by  so  much  as  a  mere  mention 
by  the  author. 

Malaria  and  Malarial  Diseases.  By  George  M. 
Sternberg,  M.D.,  F.R.M.S.,  Major  and  Surgeon 
U.  S.f  Army,  etc.  Wood's  Library  of  Medical  Authors. 
New  York  :  W.  Wood  &  Co.  1884. 
The  author  has  wisely  prepared  a  work  which  will 
be  very  welcome  to  the  general  practitioner,  as  giv- 
ing, not  the  dogmatic  views  of  a  single  person,  but  the 
combined  experience  of  observers  in  various  countries, 
ibcluding,  of  course,  our  own.  It  is  obvious  to  all  candid 
minds  that  there  are  many  puzzling  problems  connected 
with  the  subject  of  malaria.  Dr.  Sternberg  does  not  pre- 
tend to  have  solved  them.  On  the  other  hand,  we  cer- 
tainly know  considerably  more  about  malarial  diseases 
to-day  than  we  did  ten  or  even  five  years  ago.  The 
author's  treatise  is  in  the  main  an  able  and  candid  re- 
view of  the  actual  state  of  our  knowledge,  considered  in 
the  light  of  the  most  recent  researches  published  at 
home  and  abroad,  supplemented  by  the  additional  infor- 
mation derived  from  the  author's  personal  studies. 

Manual  of  Physiology.  By  Gerald  F.  Yeo,  M.D., 
F.R.C.S.,  Professor  of  Physiology  in  Kings  College, 
London,  etc.  Philadelphia :  P.  Blakiston.  1884. 
This  is  an  elementary  treatise  designed  for  the  use  of 
students.  It  is  clearly  written,  and,  while  not  too  bulky 
a  volume,  it  yet  contains  all  the  facts  necessary  to  a  com- 
prehension of  the  principles  of  physiology.  The  style  is 
much  simpler  than  that  of  Foster's  well-known  treatise, 
and  there  is  far  less  display  of  abstruse  science.  Yeo's. 
physiology  does  not  commend  itself  to  advanced  stu- 
dents, but  the  beginner  will  find  in  it  all  that  he  needs 
for  the  acquisition  of  clear  ideas  concerning  the  first 
principles  of  a  rather  complicated  science.* 

The  Human  Element  in  Sex.     Being  a  Medical  In- 
quiry into  the  Relation  of  Sexual  Physiology  to  Chris- 
tian Morality.     By  Dr.  Elizabeth  Blackwell.     Sec- 
ond Edition.     London  :  J.  &  A.  Churchill.  1884. 
This  little  work,  though  a  trifle  diffuse  in  style,  and 
perhaps  a  little  narrow  in  some  of  its  positions,  is  on  the 
whole  a  sound,  sensible,  and  useful  contribution  to  the 
subject  of  physiology  and  morals. 


iljepartB  of  ^ocijeties. 


MEDICAL    SOCIETY     OF    THE    COUNTY    OF 
NEW   YORK. 

Annual  Meeiingj  October  27,  1884. 

S.  Oakley  Vander  Poel,  M.D.,  LL.D.,  President,  in 
the  Chair. 

the  report  of  the  board  of  censors, 
together  with  the  report  of  the  counsel  of  the  So- 
ciety, E.  C.  Ripley,  Esq.,  was  read  by  Dr.  J.  W. 
Howe,  Secretary,  and  showed  that  during  the  last  year 
the  work  oi  prosecuting  illegal  practitioners  had  been 
carried  on  vigorously  and  successfully.  The  Eclectic 
Medical  College  of  the  City  of  New  York  had  been  pro- 
ceeded against  for  illegal  transactions  with  reference  to 
granting  diplomas,  and  the  prospect  was  clear  for  con- 
victing the  authorities  of  the  institution  of  having  issued 
bogus  diplomas,  and  therefore  the  annulling  of  the  charter 
of  the  college. 


the  report  of  the  committee  on  ethics 
showed  that  charges  made  by  one  member  against  an- 
other had  occurred  in  only  one  instance,  and  in  this  the 
plaintiff  had  declined  to  press  them. 

The  committee  spoke  against  the  indulgence  to  which 
physicians,  to  a  considerable  extent,  favored  themselves 
with,  by  recommending  copyrighted  medicines,  mineral 
waters,  etc. 

the  report  of  the  committee  on  hygiene 
was  read  by  Dr.  R.  Van  Santvoord,  Secretary,  and  con- 
sisted of  two  parts  :     First, 

ventilation  of  the  sewers, 
by  Dr.  E.  H.  Janes.  "  Among  the  reports  presented  by 
the  Committee  on  Hygiene  at  the  last  annual  meeting  was 
one  reflecting  somewhat  severely  on  the  method  of  ven- 
tilating public  sewers  in  this  city.  This  subject,  regarded 
by  your  committee  as  an  important  one,  has  received  con- 
siderable attention,  and  while  the  method  of  ventilation 
now  in  use  may  be  open  to  criticism,  and  in  some  locali- 
ties decidedly  objectionable,  the  present  committee  is 
not  yet  prepared  to  fully  sustain  the  report  of  its  prede- 
cessor, nor  to  suggest  any  other  plan  that  would  be 
equally  practicable  and  as  readily  controlled  by  the  public 
authorities. 

**The  principal  object  of  sewer  ventilation  is  to  protect 
the  atmosphere  of  our  dwellings  from  what  is  commonly 
called  *  sewer  gas,'  or,  what  it  is  more  properly,  sewer  air, 
with  which  is  mingled  more  or  less  of  the  products  of  or- 
ganic decomposition.  Its  necessity  arises  from  various 
causes  to  which  sewers  are  exposed.  Variations  in  tem- 
perature, the  amount  of  sewage,  efficiency  of  flushing, 
rate  of  flow,  and  condition  of  the  outlet,  all  influence  the 
development  of  deleterious  gases,  as  they  retard  or  hasten 
the  process  of  decomposition,  and  thus  bear  an  important 
relation  to  the  necessity  for  ventilation.  A  sewer  with  a 
uniform  water  supply  and  a  steady,  uninterrupted  flow 
will  require  less  means  for  ventilation  than  one  which  is 
tide-locked  twice  every  twenty-four  hours,  and  thus  sub- 
jected to  periodical  contraction  and  expansion  of  its  air 
capacity.  When  a  sewer  becomes  tide-locked,  not  only 
is  the  discharge  for  the  time  being  arrested,  but  the  con- 
tents accumulate  by  reason  of  fresh  contributions  of  sew- 
age and  tidal  influx ;  and  if  this  occurs  during  a  heavy 
rain  the  case  is  aggravated,  the  accumulations  of  sewage, 
tide,  and  storm-water  increase,  and  the  air  in  the  sewer  is 
forced  back,  being  more  and  more  compressed,  perhaps 
to  half  its  original  volume.  In  this  condition  we  have 
within  the  sewer  the  presence  of  an  additional  atmosphere 
which  no  house-trap  can  withstand.  The  method  of 
relieving  this  pressure  adopted  in  our  city,  in  the  city 
of  London,  and  indeed  in  all  the  cities  of  England,  is  to 
perforate  the  manhole-covers  that  the  imprisoned  air  may 
escape  along  the  middle  of  the  roadway,  and  thus  ming- 
ling with  the  atmosphere,  the  gaseous  products  of  decom- 
position are  readily  difl'used,  the  organic  particles  oxidized 
and  rendered  harmless.  As  the  tide  recedes  the  sewer 
is  relieved  of  its  engorgement,  the  manhole  shafts  become 
inlets  for  fresh  air,  and  thus  the  air  in  the  sewer  is  re- 
newed as  the  accumulated  sewage  is  washed  by  the 
receding  tide. 

"  During  the  period  of  low  water,  and  also  in  sewers 
that  do  not  become  tide-locked,  the  manhole  shafts  act 
alternately  as  upcast  and  downcast  shafts,  according  to 
variations  of  temperature  which' occur  at  every  discharge 
of  hot  water  from  the  house-drain,  causing  an  upward 
current  at  one  manhole  and  a  downward  one  at  the 
next.  In  proportion  as  the  air  in  the  sewer  is  thus  kept 
in  motion,  and  the  flow  of  sewage  is  uninterrupted,  will 
decomposition  be  retarded  or  prevented,  a  result  secured 
only  by  constant  motion  as  opposed  to  stagnation.  It 
does  not  appear  that  the  air  from  such  a  sewer  discharged 
through  the  manhole-covers  along  the  roadway  of  a 
street  lying  in  the  direction  of  the  prevailing  winds,  can 
be  to  any  extent  injurious  to  occupants  of  houses  on  such 
a  street.     With  stagnant  sewers  along  narrow,  crooked 


496 


THE  MEDICAL  RECORD. 


[November  i,  1884. 


streets  lined  on  either  side  with  high  buildings,  the  case 
is  different,  and  often  aggravated  by  the  discharge  of  waste 
steam  into  the  sewer,  a  practice'  which  cannot  be  too 
severely  condemned. 

"It  appears  to  your  committee  that  while  the  dangers 
arising  from  ventilating  sewers  into  the  roadway  have 
probably  been  somewhat  exaggerated,  still  a  better 
method  would  be  desirable,  could  one  equally  practicable 
be  devised  and  adopted.  It  has  been  suggested  that 
sewer  ventilation  would  be  best  and  most  safely  effected 
by  carrj^ng  a  four-  or  six-inch  pipe  from  each  house-drain 
at  a  point  between  the  trap  and  the  sewer  up  the  wall  of 
the  house  so  as  to  terminate  above  the  roof.  Were  houses 
along  a  street  of  a  uniform  height,  and  the  material  and 
joints  of  the  ventilating  pipe  impermeable  to  sewer  air, 
such  a  method  would  be  an  improvement  on  the  one  now 
in  use,  but  its  adoption  would  involve  the  interference 
of  the  authorities  with  the  rights  of  private  property  own- 
ers, which  our  citizens  are  not  yet  ready  to  grant.  A  far 
more  effective  method  would  be  to  ventilate  through  the 
house-drains  and  soil-pipes,  the  warmth  of  which  would 
.  maintain  a  constant  upward  current,  while  the  perforated 
manhole-covers  would  serve  as  inlets  for  fresh  air.  But 
as  this  method  would  require  absolute  perfection  in  our 
plumbing  arrangements,  a  condition  which  does  not  ob- 
tain in  our  city,  your  committee  cannot  think  of  recom- 
mending it." 

The  second  part  was  prepared  by  Dr.  Richard  H. 
Derby,  and  consisted  of 

NOTES   ON   CONTAGIOUS   OPHTHALMIA   IN   SOME   OF  THE 
ASYLUMS   OF  NEW   YORK   CFTY. 

After  giving  an  outline  of  the  clinical  features  of  this 
disease,  making  special  reference  to  its  contagious  char- 
acter, the  writer  directed  attention  to  the  existence  of 
the  malady  among  the  children  cared  for  in  the  larger 
asylums  of  this  city. 

In  the  asylum  for  boys  he  found  that  about  twenty- 
nine  per  cent,  had  contagious  ophthalmia;  in  the  asylum 
for  girls,  nineteen  per  cent.  In  nearly  all  these  cases* 
the  disease^  was  in  the  first  stage.  On  inspecting  the 
dormitories^and  wash-rooms  it  was  found  that  each  child 
had  its  own  bed,  separate  towel,  and  that  water  for  wash- 
ing was  supplied  from  small  jets,  at  intervals  of  one  foot, 
along  a  horizontal  pipe  above  the  sink  ;  no  basins  were 
used.  In  the  boys'  asylum  the  bath-tub  was  sufficiently 
large  to  allow  eight  to  bathe  at  the  same  time. 

In  another  of  the  largest  institutions,  28.5  per  cent,  of 
the  seniors ;  thirty-six  per  cent,  of  the  juvenile  depart- 
ment in  the  boys'  division  had  contagious  ophthalmia ; 
in  the  girls'  division  thirty  per  cent,  of  the  seniors  were 
afflicted  with  the  same  affection.  Total  number  of  chil- 
dren, 1,586. 

After  giving  similar  statistics  from  another  institution, 
Dr.  Derby  continued  that  the  conimunicability  of  the 
affection  was  strikingly  illustrated  by  the  fact  that  when 
a  group  of  children  presented  themselves  in  succession, 
they  were  those  who  habitually  occupied  adjacent  seats 
in  the  class-room. 

The  purpose  of  these  investigations  will  have  been  ef- 
fected if  the  writer  succeeded  in  drawing  attention  to 
the  fact  that  in  the  asylums  of  this  city  a  disease  fraught 
with  danger  to  the  eyes  of  all  assembled  there  exists  to 
an  alarming  extent 

The  whole  number  of  children  examined  was  3,025, 
whose  eyes  were  believed  in  the  main  to  be  healthy,  and 
25.12  per  cent.,  or  one  out  of  every  four,  had  communi- 
cable eye  disease.  To  meet  an  evil  so  great,  should  not 
a  commission  be  appointed  by  our  State  Board  of  Health, 
for  the  purpose  of  making  a  thorough  investigation  of 
the  condition  of  the  eyes  of  all  inmates  of  our  asylums 
and  reformatory  schools  ?  Should  we  not  see,^rj/,  that 
it  be  an  absolute  rule  in  these  institutions  that  no  child 
be  received  until  his  or  her  eyes  have  been  examined  by 
competent  men  ?  Second^  that  from  time  to  time  the  eyes 
of  all  inmates  of  these  institutions  should  be  examined. 


and  if  cases  of  contagious  ophthalmia  are  found  they 
should  be  isolated  and  receive  proper  treatment  ? 

For  assistance  in  making  these  investigations  he  was 
indebted  to  Dr.  W.  S.  Dennett,  of  this  city. 

On  motion  by  Dr.  C.  R.  Agnew,  the  present  Com- 
mittee on  Hygiene  was  continued  as  a  special  committee 
to  report  further  on  the  subject  of  Dr.  Derby's  contribu- 
tion. 

OFFICERS   FOR  THE   ENSUING  YEAR. 

President^  Dr.  Daniel  Lewis;  Vtce-Presideni^  Dr. 
Laurence  Johnson ;  Secretary^  Dr.  Wesley  M.  Carpen- 
ter ;  Assistant  Secretary^  Dr.  Charles  H.  Avery  ;  Treats 
urer^  Dr.  Orlando  B.  Douglas ;  Censors^  Drs.  Joseph  W. 
Howe,  Frederick  R.  S.  Drake,  Francis  M.  Weld,  Henry 
T.  Peirce,  William  Oliver  Moore. 

THE   COMMITTEE   ON   PRIZE   ESSAYS. 

Dr.  C.  C.  Lee,  Chairman,  reported  that  only  one  es 
say  had  been   submitted,  and  that  in  the   unanimous 
opinion  of  the  committee  it  was  not  sufficiently  meri- 
torious to  be  entitled  to  the  prize. 

THE   OFFICE   OF   CORONER. 

Dr.  R.  Tauszicy  offered  a  resolution  asking  the  So- 
ciety to  indorse  the  nomination  of  Dr.  Messemer  for 
Coroner.     It  was  laid  upon  the  table. 

PROPOSED   AMENDMENT  TO  THE   BY-LAWS. 

Dr.  a.  Jacobi  offered  the  following  amendment  to  the 
by-laws.  That  the  Comitia  Minora  be  directed  to  recom- 
mend no  applicant  for  admission  to  membership  unless 
he  be  a  graduate  from  a  medical  college  in  good  stand- 
ing, or  a  licentiate  of  a  regular — ^unsectanan — Stale  or 
County  Medical  Society  of  this  or  any  other  State ;  or  if 
his  certificate  be  of  sectarian  character,  unless  the  appli- 
cant declare  in  writing  his  or  her  abnegation  of  sec- 
tarian principles  and  practice.  Laid  over  under  the  rule 
until  the  next  annual  meeting. 

An  amendment  to  the  by-laws  was  adopted  providing 
that  the  stated  meeting  heretofore  held  in  the  month  of 
June  be  omitted. 

On  motion  by  Dr.  Piffard,  the  subject  of 

ARREARS   IN   DUES 

was  referred  to  the  Comitia  Minora^  to  be  reported  upon 
at  the  next  meeting  of  the  Society  with  reference  to  the 
best  method  of  dealing  with  delinquents. 

APPLICANTS   for    MEMBERSHIP    GRADUATES   OF   HOMCEO- 
PATHIC   MEDICAL   COLLEGES. 

The  Comitia  Minora^  to  which  the  applications  of  two 
candidates  for  admission  to  membership  have  been  re- 
ferred back,  because  they  were  graduates  of  homoeopathic 
medical  colleges,  reported  again,  and  recommended  that 
certificates  of  membership  be  granted  to  these  applicants. 

The  Secretary  read  letters  from  the  candidates,  in 
which  each  stated  that  he  had  resigned  from  all  homoeo- 
pathic medical  societies,  did  not  and  would  not  practise 
medicine  with  sectarian  designation,  were  in  no  way 
connected  with  homoeopathic  medical  journals,  and  were 
willing  to  be  governed  professionally  by  the  by-laws  and 
regulations  of  the  Medical  Society  of  the  County  of 
New  York. 

Dr.  £.  Eliot,  by  proxy,  offered  the  following  motion : 
That  a  diploma  from  a  homoeopathic  medical  college 
alone  must  not  be  considered  as  a  claim  for  admission  to 
membership  in  this  Society. 

The  motion  was  laid  upon  the  table,  and  the  recom- 
mendation of  the  Comitia  was  adopted. 

The  President  announced  the  deaths  of  Dr.  John 
G.  Adams,  Dr.  Joel  Foster,  Dr.  David  F.  Fetter,  and 
Dr.  Allen  S.  Church. 

The  Society  then  adjourned  to  ^meet  on  the  fourth 
Monday  in  November. 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


497 


THE  NEW  YORK   NEUROLOGICAL  SOCIETY. 

Stated  Meeting,  October  7,  1884. 

W.  J.  Morton,  M.D.,  President,  in  the  Chair. 

on  THE  nervous   ORIGIN   OF   SOME    DISORDERS   OF  THE 
ALIMENTARY   CANAL. 

Dr.  L.  Weber  read  a  'paper  on  the  above  subject  (see 

p.  481)- 
Dr.  E.  C.  Sequin,  in  opening  the  discussion,  said  that 

the  disorders  alluded  to  in  the  paper  just  read  were  far 
from  uncommon.  It  must  often  prove  quite  difficult, 
hoi^ever,  to  reach  a  positive  diagnosis.  The  abdominal 
symptoms  were  by  no  means  so  characteristic  and  well- 
defined  that  a  clear  case  could  readily  be  made  out.  It 
was  to  be  remembered  that  dyspepsia,  pure  and  simple, 
was  frequently  accompanied  by  a  variety  of  morbid 
nervous  manifestations.  In  this  countr}'  especially,  where 
we  had  both  many  dyspeptics  and  numerous  neurotics,  a 
differential  diagnosis  would  not  always  be  possible.  In 
this  connection  he  also  alluded  to  the  fact  that  the  ordi- 
nary American  diet  and  cookery  predisposed  to  gastro- 
intestinal fermentation.  He  thought  that  repeated  physi- 
cal examinations  at  different  penods,  even  of  the  same 
day,  might  aid  in  putting  a  diagnosis  on  a  firmer  basis. 
It  was  important  in  all  cases  to  separate  subjective  sen- 
sations from  true  objective  symptoms.  The  discovery  of 
the  tender  pressure-points  was  new  to  him.  He  failed  to 
see  how  hyperaesthesia  of  the  deep-seated  abdominal  nerve- 
plexuses  could  be  discovered  through  palpation.  As  re- 
garded treatment,  he  was  of  opinion  that  it  should  be  in 
the  first  place  tentative.  From  his  own  experience  he 
was  inclined  to  place  more  value  upon  a  general  tonic 
regime  than  upon  direct  and  local  medication. 

Dr.  Leszynsky  inquired  whether  Dr.  Weber  s  patients 
were  also  sufferers  from  migraine,  and  on  being  answered 
in  the  affirmative  as  regarded  two  women,  he  said  that 
Clifford  AUbutt,  in  the  recently  delivered  Gulstonian  Lec- 
tures, had  laid  stress  on  the  frequent  association  of  these 
evils. 

Dr.  Dana  stated  that  he  had  failed  to  find  evidence  of 
hyperaesthesia  of  abdominal  ganglia,  especially  of  the 
gastric  plexus,  in  cases  of  this  kind.  In  his  patients,  who 
were  generally  quite  thin.  Dr.  Seguin's  objections  touch- 
ing the  possibility  of  deciding  as  to  the  presence  of  this 
symptom  by  palpation,  had  not  been  found  to  hold  good 
He  had  been  able  to  explore  the  abdomen  in  its  deeper 
parts  very  thoroughly  in  his  cases.  He  pointed  out  that 
fermentative  dyspepsia  might  accompany,  as  an  inde- 
pendent affection,  various  neurotic  disturbances,  and  cited 
a  case  forcibly  illustrating  such  a  condition.  In  the  treat- 
ment of  neurotics  suffering  with  pronounced  gastric  dis- 
turbances he  had  found  mountain  air  beneficisd. 

Dr.  Putnam- Jacobi  thought  that  one  important  diag- 
nostic point  had  been  overlooked,  namely,  the  relation 
of  the  onset  of  the  paroxysm  of  pain  to  the  time  of  eating. 
In  purely  nervous  dyspepsia,  say  of  reflex  ovarian  or 
uterine  origin,  the  symptoms  of  gastric  distress  were  at 
their  maximum  during  the  hours  of  fasting,  and  relief 
might  be  procured  by  the  ingestion  of  food  In  fermenta- 
tive dyspepsia,  on  the  other  hand,  the  introduction  of 
food  into  the  stomach  would  only  aggravate  existing 
syniptoms.  Moreover,  pain  occurred  from  one-half  to 
two  hours  after  a  mesiL  Besides  this,  the  acid  eructa- 
tions, the  coated  tongue,  the  bad  taste  in  the  mouth  at 
morning,  should  make  differential  diagnosis  compara- 
tively easy.  In  nervous  dyspepsia  the  tongue  was  re- 
markably clean.  During,  or  even  before  a  paroxysm  of 
pam,  nausea  was  not  observed. 

Two  marked  cases  of  neurotic  dyspepsia  had  fallen 
under  her  observation  some  time  ago.  The  first  con- 
cerned a  lady,  sixty  years  of  age,  who  soon  after  having 
come  under  the  influence  of  London's  fog^y  weather,  de- 
veloped two  neuroses.  The  first  was  spiritualism,  and 
the  second  violent  paroxysmal  gastralgia.  Six  eminent 
London  physicians  decided  that  she  was  afflicted  with 


cancer.  But  Italian  sunshine  quickly  cured  her.  The 
second  case  was  that  of  a  man  who,  after  the  loss  of  a 
loved  child,  became  much  depressed  in  spirits,  and  was 
afflicted  with  gastralgic  attacks.  For  months  he  grew 
progressively  worse,  losing  flesh  all  the  time.  He  was 
eventually  completely  cured  by  arsenic.  Another  case 
had  been  cured  by  the  faradic  current.  She  thought  that 
it  was  more  difficult  to  distinguish  moderate  de^ees  of 
glandular  atrophy  of  the  stomach  from  neurotic  disorders 
than  to  separate  the  latter  from  fermentative  dyspepsia. 

Dr.  H.  D.  Chapin  believed  that  the  nervous  manifes- 
tations were  often  secondary  to  acid  fermentative  pro- 
cesses, set  up  by  the  excessive  consumption  of  starchy 
foods. 

Dr.  E.  C.  Wendt  remarked  that  it  was  quite  evident 
from  the  drift  of  the  present  discussion,  as  well  as  from 
similar  debates  in  foreign  societies,  that  ^e  entire  subject 
was  still  involved  in  considerable  obscurity.  One  thing 
was  certain,  however,  namely,  that  the  profession  in  all 
civilized  countries  was  beginning  to  reinstate  the  nervous 
system,  in  its  relation  to  disease-development,  into  a  for- 
merly occupied  position  of  pre-eminence.  Not  many  years 
ago  the  pathological  school  had  been  so  exclusively  domi- 
nant that  functional  disorders  had  been  almost  relegated 
to  the  limbo  of  the  mythical.  Within  the  past  few  years, 
however,  a  great  change  had  set  in,  and  at  present  there 
seemed  to  be,  if  anything,  a  danger  of  falling  into  the 
other  extreme.  Certain  it  was  that  to-day  there  either 
was  much  less  gastro-intestinal  catarrh,  or  else  it  was 
more  frequently  overlooked  than  formerly;  while  on 
the  other  hand  nervous  dyspepsia  must  either  be  of  much 
more  frequent  occurrence,  or  else  be  erroneously  assumed 
to  exist  in  true  structural  disease  of  the  alimentary  canal. 
Clifford  AUbutt  had,  in  the  recently  delivered  Gulstonian 
Lectures,  drawn  some  vivid  pictures  of  this  class  of 
cases,  and  the  whole  subject  had  been  but  lately  dis- 
cussed at  the  third  German  Congress  of  Internal  Medi- 
cine. At  that  meeting  Leube  had  reiterated  his  former 
well-known  views  on  nervous  dyspepsia.  But  he  had 
been  opposed  by  several  competent  observers,  prominent 
among  whom  was  Ewald.  The  latter  took  the  ground 
that  real  disease  of  the  stomach  might  start  the  entire 
train  of  nervous  symptoms  so  often  seen  in  neurotics. 
Trousseau's  veriige  stomacale^  dyspeptic  migraine,  and 
Rosenbach's  cases  of  vagus  neurosis  were  some  of  the 
rarer  manifestations  belonging  to  this  category.  Ewald 
further  asserted  that  Leube's  well-known  Verdauungs- 
versuch  had  no  great  practical  value,  for  he  had  in 
many  instances  found  food-particles  in  the  water  used 
for  washing  out  th<5  stomach  seven  hours  after  a  simple 
meal.  So  also  he  had  found  the  gastric  fluid  in  positive 
structural  disease,  such  as  cancer  and  chronic  catarrh, 
to  give  normal  chemical  reactions.  Dr.  Wendt  thought 
it  was  quite  evident  from  all  this  that  we  still  lacked 
decidedly  characteristic  or  pathognomonic  symptoms  of 
this  class  of  disorders.  It  should  never  be  forgotten  that 
dyspepsia  was  not  a  disease  in  itself,  but  might  be  a 
symptom  of  very  many  vastly  dissimilar  affections.  To 
the  presence  or  absence  of  painful  pressure-points,  sup- 
posed by  Burckart  to  be  characteristic  of  nervous  dys- 
pepsia, he  had  not,  from  his  own  experience,  learned  to 
attach  any  significance.  He  also  thought  that  the  term 
gastric  neurasthenia,  suggested  by  Burckart,  was  not  a 
happy  selection.  Such  cases  should  be  classified  rather 
under  the  general  heading  of  "  nervous  disorders  of  the 
alimentary  canal."  One  point  he  wished,  however,  to 
emphasize,  namely,  that  nervous  dyspepsia  did  not  kill. 
He  had  seen  such  patients  apparently  brought  to  the  very 
door  of  death,  but  in  the  end  they  had  invariably  recov- 
ered. One  case  he  remembered  in  particular,  that 
was  almost  the  exact  counterpart  of  the  first  case 
mentioned  by  Dr.  Jacobi.  Here  too,  eminent  phy- 
sicians had  been  misled,  probabl^r  by  the  cachectic 
appearance  of  the  patient,  to  magnosticate  gastric 
cancer.  But  the  lady  in  question  fully  recovered, 
and  at  present,   six  years  after  she    had  been  given 


498 


THE  MEDICAL  RECORD. 


[November  i,  1884. 


up,  she  was  better,  stronger,  and  weighed  more  than 
at  any  other  period  of  her  life  that  she  could  recol- 
lect Finally,  as  regarded  treatment,  he  thought  that 
general  and  hygienic  measures  were  more  calculated  to 
benefit  sufferers  of  this  class  than  drugs.  Absolute  rest 
was  at  times  imperative.  Of  drugs  he  thought  arsenic 
was  the  best  for  the  intervals,  and  morphine  subcutane- 
ously  or  in  suppositories  for  paroxysmal  pain. 

Dr.  Morton  alluded  to  the  ready  supervention  of 
diarrhoea  through  emotional  disturbances  in  neuras- 
thenics. Animals  under  excitement  often  showed  simi- 
lar symptoms,  but  he  did  not  wish  to  infer  for  this  reason 
that  they  too  were  afflicted  with  neuroses. 

Dr.  Tked,  of  Kansas  City,  raised  the  query  whether 
we  were  not  painting  old  facts  in  new  colors.  He  believed 
that  all  the  troubles  mentioned  in  the  paper  and  the  dis- 
cussion could  be  included  under  the  old  designation  of 
atonic  dyspepsia.  His  explanation  of  the  origin  of  these 
disturbances  was  as  follows  :  Nervous  influence  that 
should  be  sent  to  the  stomach  became  diverted  into  other 
channels,  and  as  a  consequence  the  gastric  glands  failed 
to  perform  their  function.  Besides  this,  nerve  stimula- 
tion might  happen  in  the  stomach,  be  thence  transmitted 
to  the  central  nerve-organs,  and  once  more  reflected 
back  upon  the  stomach.  Ingestion  might  in  this  way 
lead  to  watery  secretion  and  thus  result  in  copious 
evacuations.  But  the  neurotic  taint  might  manifest  its 
existence  through  other  organs  besides  the  stomach. 
Cardiac  palpitation  might  occur.  The  latter  might  even 
co-exist  with  gastric  distress  and  yet  the  consummation  of 
digestion  be  neither  retarded  nor  in  any  other  way  dis- 
turbed. 

The  great  point  to  know  was,  where  did  all  the  nerve- 
force  come  from  ?  How  did  it  originate  in  the  body  ? 
In  his  opinion  it  ultimately  depended  entirely  upon 
oxidation  or  some  similar  chemical  change  constantly 
taking  place  in  organized  beings.  He  thought  that  the 
various  cells  of  the  body  might  be  likened  to  minute 
electric  batteries  that  were  perpetually  active.  Through 
their  agency  force  was  liberated  which  primarily  assumed 
the  form  of  heat.  In  this  way  currents  were  normally 
sent  to  the  brain  and  again  started  out  from  the  enceph- 
alon  to  other  parts. 

Of  course,  if  the  paths  of  conduction  became  altered 
failure  of  force-transmission  must  result  This  gave  rise 
to  morbid  symptoms  which  we  must  endeavor  to  inter- 
pret He  also  compared  the  relations  of  the  cerebro- 
spinal with  the  sympathetic  nervous  system  to  the  two 
wires  of  a  battery.  One  thing  was  certain,  namely,  that 
new  matter  or  new  force  had  no  existence  in  the  human 
body.  The  same  physical  laws  that  governed  the  outer 
world  also  held  good  for  our  bodies.  It  was  essential, 
therefore,  to  know  well  the  rules  and  laws  of  the  trans- 
mission and  radiation  of  force  in  the  outer  world  before 
we  could  hope  to  understand  the  actual  condition  of 
nerve-action  within  us. 

Dr.  Weber,  in  closing  the  discussion,  said  that  he 
agreed  with  Dr.  Seguin  in  the  importance  which  he  at- 
tached to  a  thorough  examination  of  cases  of  dyspepsia 
of  whatever  nature,  particularly  as  to  the  presence  of 
dilatation,  but  believed  that  dilatation  was  not  only  liable 
to  occur  when  patients  indulged  in  too  liberal  quantities 
of  farinaceous  food  and  sweets,  but  also  by  the  vicious 
habit  which  many  people,  young  and  old,  had  of  putting 
much  more  food  into  Uieir  stomachs  at  a  given  meal  than 
the  organ  ought  to  receive  at  one  time.  Like  Dr.  Dana, 
he  had  not  been  able  thus  far  to  verify  Dr.  Burckart's  ex- 
periences as  to  the  tenderness  of  one  or  more  of  the 
abdominal  sympathetic  ganglia  in  certain  cases  of  gastric 
neurasthenia. 

The  good  results  which  Dr.  Putnam-Jacobi  and  others 
had  seen  from  small  doses  of  arsenic  in  the  management  of 
these  disorders  he  was  ready  to  accept  as  an  illustration 
of  rational  therapeutics.  He  had  himself  seen  excellent 
results  from  drop-doses  of  Fowler's  solution,  taken  on 
an  empty  stomach,  in  the  early  morning  retching  and 


vomiting  of  habitual  topers.  He  believed  that  Dr. 
Wendt  was  right  when  he  said  that  Dr.  Burckart's  desig- 
nation of  *^  neurasthenia  gastrica"  was  not  happily  chosen, 
and  that  the  general  name  of  '^  nervous  disorders"  would 
be  better. 

PSEUDO-BULBAR  PARALYSIS. 

Dr.  William  Browning,  of  Brooklyn,  read  a  paper 
illustrating  the  above  condition  (see  p.  487). 

Dr.  £.  C.  Seguin  related  a  case  of  bulbar  disease 
which,  if  not  quite  germane  to  the  present  subject,  was 
intrinsically  so  interesting  as  to  merit  the  notice  of  the 
Society. 

Male,  forty-four  years  of  age,  seen  January  31, 1876,  in 
consultation  with  Dr.  M.  J.  Moses.  Denies  syphilis  or 
recent  sore  throat  Well  up  to  January  ist,  when  he 
had  epileptiform  attacks  limited  to  the  limbs  of  the 
left  side ;  in  one  attack  the  tongue  was  bitten.  No  recur- 
rence of  attacks.  Subsequently  severe  right  supraorbital 
neuralgia  cured  by  arsenic.  On  January  29th  sudden  in- 
ability to  swallow  solids  developed  in  four  or  five  hours. 
Examination  shows  a  spasm  (?)  two  inches  below  pharynx. 
The  voice  is  nasal  and  articulation  is  imperfect.  Patient 
is  conscious  of  the  labor  of  speaking. 

In  view  of  the  rapid  development  of  the  symptoms,  I 
expressed  the  opinion  that  the  case  was  not  one  of  true 
bulbar  paralysis  of  the  progressive  form,  but  an  acute 
paralysis  due  perhaps  to  an  ignored  diphtheria,  and  that 
the  prognosis  was  not  quite  hopeless. 

On  February  7th,  nine  days  after  the  appearance  of 
dysphagia.  Dr.  Moses  sent  the  patient  bade  to  me  with 
the  following  letter : 

«*  My  Dear  Doctor  :  I  asked  Mr.  S to  call  upon 

you  and  deliver  this  note,  which  for  obvious  reasons  I 
send  sealed.  I  am  afraid  he  shows  more  progressive 
symptoms  than  when'  you  last  saw  him,  and  that  the 
prognosis  made  now  would  not  be  quite  as  favorable.  I 
think  it  will  be  necessary  to  put  you  in  possession  of  all 
that  has  happened  since  last  Monday  when  you  first  saw 
him. 

"On  Monday  evening  he  lost  the  power  of  swallowing 
fluids,  and  I  passed  a  stomach-tube,  but  it  produced  such 
irritation  that  he  almost  suffocated  from  spasm  of  the 
glottis  when  the  tube  was  in  his  stomach.  I  passed  the 
tube  several  times,  but  each  time  was  forced  to  withdraw 
it  to  avoid  a  catastrophe.  I  finally  hit  upon  an  idea 
which  I  congratulate  myself  and  the  patient  upon.  Hav- 
ing learned  from  previous  examination  that  the  middle 
and  lower  muscles  of  constriction  were  not  as  much  in- 
volved, I  made  my  patient  lie  down  and  permit  the 
mouthfiil  of  fluid  to  flow  down  below  the  edge  of  the 
velum,  and  then  to  swallow.  This  efibrt  raised  the  larynx 
and  propelled  the  fluid  within  the  grasp  of  the  lower  con- 
strictors.    By  this  device  (lp^8  down  at  each  mouthfol, 

with  the  head  thrown  far  back)  Mr.  S was  able  to 

take  sufficient  nourishment,  milk,  eggs,  and  beef-tea, 
and  his  medicine,  viz.,  quinine,  iron,  and  strychnia  in  so- 
lution, during  yesterday  and  Wednesday. 

"  On  Tuesday,  by  violent  eflfort,  he  was  enabled  to  swal- 
low sitting  up,  but  at  the  same  time  I  noticed  marked 
loss  of  power  in  the  muscles  of  the  cheeks  and  lips,  and 
an  aggravation  of  his  nasal  speech.  I  noticed  also, 
steadily  progressing,  an  irritation  of  the  pneumogastrics, 
evinced  by  violent,  prolonged,  and  characteristic  cough. 
The  irritation  is  almost  constant,  touching  the  throat 
with  an  electrode  or  the  eflfort  of  swallowing  bringing  on 
a  most  violent  paroxysm.  I  have  faradized  the  muscles 
of  the  pharynx  with  a  gently  increased  current,  and  gal- 
vanized the  spinal  accessory  and  glosso-pharyngeal  with 
from  four  to  six  cells  of  Kidder's  eighteen-cell  bat- 
tery. At  first  each  was  well  borne,  but  yesterday  a  very 
mild  current  from  either  battery  provoked  vomiting,  and 
on  passing  a  current  Irom  six  cells  over  the  pneomo- 
gastric,  I  provoked  a  prolonged  and  almost  exhaustive 
cough.  I  am  afraid  the  disease  is  progressive  and  due  to 
central  lesion.     I  send  him  to  you  for  another  examina- 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


499 


tion,  that  you  may  compare  his  present  condition  with 
the  result  of  your  examination  last  Monday,  and  see  if 
some  new  points  may  not  have  arisen  to  point  to  you  a 
separation  of  the  two  theories  then  presenting,  viz. :  labio- 
glosso-pharyngeal,  or  diphtheritic  paralysis.     .     .    . ' 

Examination  :  speech  not  as  good ;  whistling  is  pos- 
sible but  feeble ;  can't  fill  cheeks  with  air ;  much  saliva- 
tion ;  orbiculus  oris  weaker,  but  can  still  make  O.  The 
tongue  moves  well  in  all  directions.  Voice  not  as  loud  as 
at  last  note.  Much  cough  (more  morning  and  night). 
Throat  very  irritable.  No  facial  palsy  (apart  from  orbic 
and  buccinator  paresis).  Voice  very  nasal  and  articu- 
lation is  impaired.  In  speech  and  by  reflex  action  soft 
pahite  acts  well.  Fails  to  swallow  a  morsel  of  bread, 
and  the  laryngoscopic  mirror  shows  it  lying  behind  the 
glottis  a  little  to  the  left.  Rima  glottidis  red;  vocal 
cords  not  seen ;  no  anaesthesia  of  face  or  hands ;  no 
hemiplegia. 

It  should  be  added  that  two  years  ago  patient  had 
neuralgia  of  the  left  side  of  the  face  and  paralysis  of  the 
left  vocal  cord.  Again  denies  syphilis.  I  adhered  to  my 
dia^osis  of  acute  non-progressive  bulbar  paralysis,  and 
advised  continuing  the  iron  and  strychnia  and  using 
weak  galvanism  to  back  of  neck  And  outside  of  throat. 
My  notes  are  not  complete,  but  I  can  state  that  the 
patient  recovered  somewhat  slowly  but  completely  in  a 
few  weeks. 

Dr.  Morton  alluded  to  two  cases  of  hysterical  simula- 
tion of  bulbar  disease  that  had  been  on  the  point  of 
being  reported  as  instances  of  progressive  bulbar  paraly- 
sis, when  both  recovered  completely. 

Dr.  Seguin  said  that  the  converse  mistake  had  once 
happened  to  him.  It  was  a  case  which,  owing  to  the 
absence,  at  the  first  visit,  of  labial  symptoms  and  the 
predoniinance  of  palatal  disturbance,  was  held  to  be  not 
a  genuine  instance  of  progressive  bulbar  disease.  At  the 
second  visit,  however,  difficulty  of  swallowing  and  other 
signs  left  no  doubt  as  to  the  true  nature  of  the  affection. 


NORTHWESTERN    MEDICAL   AND   SURGICAL 
SOCIETY  OF  NEW  YORK. 

Stated  Meeting,  April  18,  1884. 

E,  C.  Harwood,  M.D.,  President,  in  the  Chair. 

Dr.  Edward  S.  Peck  read  a  paper  (see  p.  482)  on 

MINERAL  ASTRINGENTS    AND    CAUSTICS    IN    OPHTHALMIC 
PRACTICE. 

Dr.  Baruch  objected  to  the  use  of  the  word  caustic 
as  implied  in  the  paper,  as  it  was  not  its  usual  significa- 
tion. Caustics  and  astringents  present  this  great  diflference, 
that  the  former  are  destructive,  and  the  latter  produce 
their  effect  without  destruction  of  tissue.  In  the  groups  of 
conjunctivitis  alluded  to,  silver-nitrate  should  be  regarded 
as  an  astringent.  Silver-nitrate  is  not  a  caustic  in  liquid 
form ;  it  is  not  destructive  except  by  violent  application. 
It  acts  rather  as  a  modifier  of  the  action  of  disease. 

Dr.  Page  uses  tepid  water  in  painful  forms  of  con- 
junctival inflammation ;  has  been  led  to  believe  cold 
water  injurious,  and  has  never  used  silver-nitiate.  He 
cited  a  case  of  recurrent  phlyctenular  conjunctivitis, 
which  was  brought  on  by  overwork  at  school,  and  was" 
successfully  treated  by  general  treatment  with  calomel 
applied  locally  to  the  eyes.«| 

Dr.  Knapp  agreed  with  the  paper  in  its  differentiation 
as  to  the  selection  of  caustics,  especially  the  sulphate  of 
copper  stick  in  chronic  granular  conjunctivitis ;  but  the 
longer  he  practises  in  such  diseases  the  more  restricted  is 
his  use  of  caustics.  So  long  as  a  conjunctivitis  is  acute, 
he  abstains  from  powerful  remedies ;  he  uses  cold  com- 
presses day  and  night.  When  the  disease  is  in  danger  of 
becoming  chronic,  then  he  uses  caustics  and  astringents. 
In  the  ophthalmia  of  scrofulous  individuals,  he  has  ordered 
the  head  to  be  dipped  in  pails  of  cold  water,  and  with 


very  good  results.  The  peculiar  form  of  vernal  conjunc- 
tivitis brought  out  in  the  paper  he  believed  to  be  endemic 
in  character ;  no  treatment  seemed  to  be  of  avail  He 
prefers  mild  alkaline  washes ;  astringents  seem  to  do  no 
good. 

Dr.  Bosworth  used  silver-nitrate  only  on  the  mucous 
patch  in  throat  cases.  He  has  abandoned  all  solutions 
of  the  salt  in  treatment  of  throat  diseases.  Cold  water  is 
always  an  irritant  to  columnar  epithelium. 

Dr.  Wood  thought  the  hygienic  surroundings  of  patients 
suffering  firom  granular  conjunctivitis  were  frequently  at 
fault ;  upon  the  correction  of  these  depended  the  suc- 
cess of  treatment  of  such  cases.  In  the  ophthalmia  of 
the  newly-born,  whether  simple  or  gonorrhoeal,  mild  treat- 
ment met  all  requirements.  Constant  washing  out  with 
hot  water,  and  dropping  mild  alum  water  into  the  eye 
three  or  four  times  a  day,  constituted  his  treatment  in 
such  cases. 

Dr.  McLaury  had  used  hot*  water  with  best  effect  in 
similar  cases  of  purulent  ophthalmia  of  infants. 

Dr.  Jacobus  believed  the  pain  which  was  felt  on  the 
application  of  cold  water  to  a  mucous  membrane  was 
caused  by  a  swelling  and  rupture  of  the  epithelium.  If 
salt  in  the  proportion  of  about  one  drachm  to  one  pint 
of  water  be  used,  it  becomes  similar  to  the  physical  fluids. 
In  gonorrhoeal  ophthalmia  he  uses  hot  water  for  cleansing 
and  vaseline  to  keep  the  lids  apart. 

Dr.  Agnew  premised  his  remarks  by  saying  that  thirty 
years  ago  caustics  and  antiphlogistics  were  much  used  in 
ocular  affections.  Now  he  does  not  use  silver-nitrate  in 
any  form,  either  in  private  or  public  practice,  and  copper 
but  a  very  few  times  in  the  course  of  a  year.  He  relies 
upon  general  treatment  more  and  more  each  year.  He 
believed  topical  applications  had  been  carried  to  excess. 
The  cold  douche  was  just  the  tonic  needed  in  some 
chronic  forms  of  conjunctiva]  disease.  Keeping  the  parts 
clean  was  an  important  point  always  to  be  had  in  mind. 
Hot  water  was  now  used  where  formerly  cold  had  been 
employed.  He  believed  that  the  highest  attention  should 
be  paid  to  tissue-building. 

Dr.  Jarvis  thought  the  amount  of  silver-nitrate  em- 
ployed should  determine  whether  its  effect  was  or  was 
not  caustic  It  acts  mechanically  by  producing  an  al- 
buminate, thus  securing  protection  to  the  subjacent  parts ; 
this  action  is  chemically  astringent  When  firequently 
employed  it  produces  destruction  of  tissue,  and  should  be 
regarded  as  caustia 

Dr.  Fruitnight  corroborated  the  statement  made  by 
the  author  of  the  paper  as  to  the  etiology  of  cases  of 
purulent  ophthalmia  of  the  newly-born  not  being  neces- 
sarily gonorrhoeal ;  he  had  seen  a  number  of  such  cases 
where  the  mother  was  positively  free  from  the  disease. 
He  uses  in  such  cases  very  hot  water  with  alkalies,  usu- 
ally borax,  with  best  effect 

Dr.  Knapp  further  sUted  that  Ernst  Henry  Weber, 
physiologist  of  Leipzig,  first  introduced  the  use  of  cold 
water  in  treatment  about  forty  years  ago.  It  was  the  im- 
bibition  of  water  by  the  epithelial  cells  which  caused  pain 
during  the  use  of  cold  water. 

The  President  stated  that  he  uses  ice-bags  as  com- 
presses to  the  eyelids,  and  has  also  used  cold  as  well  as 
hot  water  as  a  styptic  in  ophthalmic  practice. 

In  reply  to  a  question.  Dr.  Knapp  said  it  was  his  prac- 
tice to  use  ice-bags  to  the  closed  eyelids,  but  hot  water 
for  cleansing  mucous  membranes. 

In  closing  the  discussion  Dr.  Peck  said  that  by  the 
word  caustic  was  implied  a  destructive  agent,  and  by 
astringent  the  usual  pharmacological  acceptance  of  that 
class  of  agents.  As  the  lines  of  discussion  had  turned 
upon  the  use  of  cold  and  hot  water  in  ophthalmic  treat- 
ment, he  offered  the  statement  that  the  final  effect  of  hot 
fomentations  and  ice-cold  lotions  was  the  same.  He 
suggested  that  an  application  of  cold  can  only  be  con- 
tinued as  such  by  a  thin  layer  of  muslin  or  linen,  taken 
from  raw  ice,  transferred  to  the  closed  eye,  and  changed 
so  soon  as  it  acquired  a  temperature  near  to  that  of 


500 


THE  MEDICAL  RECORD. 


[November  i,  1884. 


the  body ;  a  hot  lomentation  or  compress  must  be  of  sev- 
eral thicknesses  of  fabric,  as  a  fresh  laundried  hand- 
kerchief, wrung  out  of  hot  water,  covered  with  dry  flan- 
nel, and  renewed  so  soon  as  it  became  reduced  to  near 
the  animal  temperature.  The  term  cold  compress  is  an 
anomaly.  He  uses  cold  cloths  in  this  way  to  combat 
acute  forms  of  conjunctivitis;  he  also  uses  hot  water 
saturated  with  boracic  acid  as  an  irrigant  in  ophthalmias 
attended  with  discharge.  It  is  a  well-attested  clinical  fact 
that  patients  like  hot  applications  better  than  cold. 

OUR  LONDON  LETTER. 

(From  our  Special  Correspondent) 
THE  MEDICAL  COUNCIL'S  AUTUMN  SESSION — CONJOINT 
EXAMINATION  SCHEMES — ^THE  COLLEGE  OF  SURGEONS 
AND  THE  WILSON  BEQUEST — NEW  DRAINAGE  SCHEME 
FOR  LONDON — ^THE  PUBLISHING  SEASON — NEW  WORKS 
AND  NEW  EDITIONS — ^THE  ENTRIES  AT  THE  MEDICAL 
SCHOOLS — OVER-PRESSURE   IN   BOARD   SCHOOLS. 

London,  October  x8,  1884. 

The  General  Medical  Council  met  October  7th.  As 
might  have  been  expected  from  such  an  essentially  con- 
servative body,  Sir  Henry  Acland  has  been  re-elected 
President  for  a  third  term  of  five  years.  I  cannot  chron- 
icle any  important  proceedings  on  the  part  of  the  Council. 
Medical  education  and  examinations  were  discussed,  but 
it  is  of  little  consequence  what  conclusions  the  Council 
arrive  at  as  they  have  no  power  to  enforce  their  own 
recommendations.  A  considerable  amount  of  time  was 
spent  in  discussing  Sir  Henry  Pitman^s  motion,  sanction- 
ing the  proposed  conjoint  scheme  on  the  part  of  the 
College  of  Physicians  and  the  College  of  Surgeons. 
This  has  been  mooted  many  times  but  has  never  come 
to  anything.  The  object  is  to  do  away  with  partially 
qualified  practitioners.  At  present,  although  the  College 
of  Surgeons  examine  in  medicine  and  obstetrics  as  well  as 
in  surgery,  it  is  only  legally  a  qualification  to  practise 
surgery.  Similarly  the  license  of  the  Apothecaries'  Hall 
is  only  legally  a  title  to  practise  medicine  and  midwifery. 
There  are  still  a  good  many  men  in  practice  who  possess 
only  one  of  these  diplomas. 

The  license  of  the  College  of  Physicians  is  a  qualifica- 
tion entitling  its  possessor  to  practise  all  three  branches. 
It  is  now  proposed  (not  for  the  first  time)  that  the  Col- 
lege of  Physicians  should  relinquish  their  right  to  qualify 
in  surgery,  and  only  give  diplomas  in  connection  with 
the  College  of  Surgeons.  In  the  discussion  on  this  sub- 
ject at  the  meeting  of  the  Medical  Council  on  the  8th 
inst.,  Dr.  Quain  opposed  this  scheme  strongly,  and  refer- 
ring to  the  Surrical  College  said :  "  That  amiable  fox 
living  in  Lincoln's  Inn  Fields,  which  never  had  a  tail, 
went  to  the  College  of  Physicians  and  said,  How  beau- 
tiful I  am  without  a  tail !  do  drop  your  tail  and  be  like 
me.'*  Sir  Henry  Pitman's  motion  was,  however,  carried, 
although  the  weak  points  in  it  had  been  pretty  plainly 
pointed  out  by  Dr.  Quain  in  a  lengthy  speech.  The  in- 
stituting a  complete  diploma,  qualifying  in  all  branches 
of  practice,  and  one  which  is  accepted  for  all  Govern- 
ment appointments,  is  one  of  the  best  things  the  College 
in  Pall  Mall  ever  did  for  the  profession,  and  it  is  to  be 
hoped  it  will  think  twice  before  relinquishing  its  right. 
It  has,  too,  paid  the  College  pretty  well. 

The  best  thing  for  the  College  of  Surgeons  would  be 
to  get  their  diploma  recognized  as  a  complete  qualifica- 
tion likewise.  They  ought  to  be  able  to  do  something 
now,  for  it  is  estimated  that  the  Erasmus  Wilson  bequest 
will  amount  to  nearly  two  hundred  thousand  pounds,  in- 
stead of  one  hundred  and  eighty  thousand,  as  at  first 
expected.  One  suggestion  is  that  they  should  endeavor 
to  obtain  a  charter  transforming  the  college  into  a  uni- 
versity, empowered  to  grant  degrees  in  medicine  and 
«urgery,  and  located  in  splendid  new  buildings  erected 


on  one  of  the  sites  still  vacant  on  the  Thames  Embank- 
ment. 

Speaking  of  the  Thames  reminds  me  of  the  new  drain- 
age scheme  of  the  Metropolitan  Board  of  Works.  Your 
readers  will  be  astonished  to  learn  that,  after  spending 
millions  of  pounds  upon  the  drainage  of  London,  a 
radical  change  should  be  necessary  and  desirable. 
What  is  proposed  in  the  new  scheme  is  virtually  to  con- 
struct an  enormous  conduit  (which  would,  I  suppose,  be 
at  least  ten  miles  long)  to  convey  the  sewage  down  to 
the  seacoast  in  Essex.  When  it  reached  the  coast  it 
would  be  necessarily  (from  the  gradients  of  the  conduit) 
far  below  sea-level,  and  to  pump  it  into  the  sea  at  ebb- 
tide machinery  would  have  to  be  erected  still  more 
enormous  and  costly  than  that  now  in  use  at  Crossness 
and  Barking.  It  goes  without  saying  that  this  proposal 
does  not  receive  unqualified  or  even  unanimous  approval 
from  sanitary  authorities.  Economists  have  protested 
for  years  against  the  fearful  waste  involved  in  pouring  all 
the  sewage  into  the  river,  to  say  nothing  of  the  pollution 
of  the  stream  itself.  The  latter  would  be  removed  by 
the  new  plan,  but  the  former  would  still  go  on.  The 
crux  is  the  enormous  bulk  of  sewage  with  which  we  have 
to  deal  Still  something  might  be  tried.  Meanwhile 
the  scheme  just  described  is  all  that  the  collective  wis- 
dom of  the  Board  of  Works  has  been  able  to  devise.  It 
remains  to  be  seen  whether  it  will  be  carried  into  effect 

The  approach  of  winter  is,  as  usual,  accompanied  by 
increased  activity  on  the  part  of  medical  publishers. 
Taking  students'  manuals  only,  quite  a  number  of  new 
books  and  new  editions  are  either  announced  or  have 
recently  appeared,  and  of  other  works  there  is  quite  the 
usual  supply. 

A  work  which  will  be  looked  for  with  considerable  in- 
terest is  a  volume  of  clinical  lectures  by  Mr.  Richard 
Quain,  F.R.S.,  which  is  announced  as  being  in  the  press. 
(This  gentleman  must  not  be  confounded  with  his  emi- 
nent namesake,  Dr.  Richard  Quain,  the  editor  of  the 
**  Dictionary  of  Medicine  "  which  bears  his  name.)  This 
venerable  professor  so  seldom  appears  in  print  and  has 
been  so  long  retired  from  active  practice,  that  his  coming 
volume  will  be  received  with  unusual  interest. 

Mr.  Watson  Cheyne  announces  another  book  on  "The 
Antiseptic  Method  in  Surgery."  This  (the  second  work 
by  him  on  this  subject)  will  doubtless  contain  some  of 
the  results  of  the  researches  in  the  Biological  laboratory 
of  the  Health  Exhibition. 

New  editions  have  appeared  simultaneously  of  Erich- 
sen's  and  Bryant's  works  on  surgery.  The  former  has 
been  considered  as  the  leading  text-book  for  many  years 
past  now,  although  its  diffuse  and  wordy  style  and  its 
bulk  have  been  great  drawbacks  to  its  use  by  average 
students.  In  successive  editions  it  has  swelled  and 
swelled  until  in  size  it  threatens  to  rival  if  not  outstrip 
the  "  System  of  Surgery,"  of  which  a  new  and  (by  a  re- 
arrangement of  type)  smaller  edition  only  appeared  last 
year.  The  latter  work,  though,  is  likely  to  find  a  formid- 
able rival  in  **  The  International  Cyclopaedia  of  Surgery." 

A  fifth  edition  of  Playfair's  *<  Midwifery"  is  announced. 
Since  its  first  publication,  only  eight  years  ago,  it  has  rap- 
idly become  the  favorite  text-book,  to  the  practical  exclu- 
sion of  all  others.  Lusk's  treatise  has  displaced  it  some- 
what for  the  higher  examinations,  but  for  all  others  it  is 
still  widely  read.  A  large  measure  of  its  popularity  is 
due  to  the  clear  and  easy  style  in  which  it  is  written. 
Few  text-books  for  students  have  very  much  to  boast  of 
in  this  respect.  The  best  one  is,  perhaps,  the  well-known 
"Manual  of  Surgery,"  from  the  pen  of  Mr.  Timothy 
Holmes,  the  editor  of  the  "  System."  Dr.  Robert  Barnes 
is  also  an  able  penman,  and  his  work  on  "Obstetric 
Medicine  and  Surgery,"  written  jointly  by  himself  and 
his  son,  is  certain,  when  completed,  to  find  a  large  circle 
of  readers. 

Readers  of  works  on  medicine  are  less  favored.  The 
two  standard  books  are  "Roberts"  and  '*  Bristowe,"  and 
of  both  of  these  new  editions  have  been  issued  during  the 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


501 


past  eighteen  months.  The  former  is  doubtless  a  useful 
compilation  for  examination  purposes,  but  not  an  inter- 
esting work  to  read  otherwise.  Bristowe  is  perhaps  a 
little  more  lively  writer,  but  even  he  makes  us  long  for  a 
return  of  the  literary  grace  which  adorned  the  pages  of 
Dr.  Graves  and  Sir  Thomas  Watson.  Both  of  these 
works,  too,  sound  a  very  uncertain  note  in  the  matter  of 
treatment  Numerous  drugs  are  mentioned  under  the 
various  diseases,  but  the  directions  as  to  their  administra- 
tion are  very  vague.  We  are  now  promised  a  new  text- 
book of  medicine  in  the  form  of  a  posthumous  work  by 
the  late  Dr.  Hilton  Fagge.  It  is  to  be  in  two  volumes,  and 
from  Dr.  Fagge's  well-known  learning  and  industry  is 
likely  to  present  a  faithful  reflection  of  the  present  state  of 
medical  knowledge,  and  more  especially  of  the  teaching 
at  "Guy's." 

The  number  of  *'full  entries"  at  the  medical  schools 
for  the  winter  session  is  between  five  and  six  hundred. 
By  ''  full  entries  "  is  meant  the  number  of  students  en- 
tered for  the  full  course  of  four  years  at  the  hospitals. 
From  this  period  of  time  eighteen  months  is  remitted  in 
the  case  of  those  who  have  served  a  pupilage  of  that 
dm-ation  with  a  general  practitioner.  This  applies  only 
to  candidates  for  the  ordinary  diplomas.  The  Universi- 
ties require  the  whole  period  of  four  years  to  be  passed 
in  hospital  study,  and  the  College  of  Surgeons  exacts  a 
curriculum  of  six  years  for  its  Fellowship  from  those  who 
wish  to  take  it  from  their  hospital  at  once.  Graduates  in 
Arts  are  allowed  a  year  off  this. 

The  discussion  on  over-pressure  in  board  schools,  which 
was  initiated  by  the  publication  of  Dr.  Crichton  Browne's 
report  on  the  subject,  is  still  ^oing  on.  It  appears  that 
after  inviting  Dr.  Browne  to  inspect  and  report  on  cer- 
tain schools,  accompanied  by  Mr,  Fiichy  one  of  the  Govern- 
ment Inspectors^  the  Education  Department,  not  finding 
the  report  to  their  taste^  first  tried  to  suppress  il  and  then 
endeavored  to  upset  Dr.  Browne's  conclusions,  and  set 
Mr.  Fitch  to  abuse  him.  Dr.  Crichton  Browne  has 
opened  fire  on  his  assailants  in  the  columns  of  The 
Times^  and  seems  to  be  getting  the  better  of  them.  The 
whole  subject  will  probably  be  well  ventilated  when  Par- 
liament meets.  Meanwhile,  among  the  medical  profes- 
sion at  any  rate,  the  opinion  is  pretty  general  that  it  has 
been  clearly  proved  that  over-pressure  does  exist.  The 
late-payers  have  long  thought  so — but  for  another  reason. 


THE    DANGER    OF    OPIUM-SMOKING   AS    A 
THERAPEUTIC   MEASURE. 

To  THB  Editor  of  Thb  Mkoical  RBcoBOb 

Sir  :  In  the  issue  of  The  Medical  Record  for  Septem- 
ber 2oth,  page  317,  I  notice  a  short  article  in  reference 
to  "  Opium-Smoking  as  a  Therapeutic  Measure."  Now, 
while  we  will  all  agree  with  Dr.  Thudichuro  that  opium- 
smoking  may  prove  a  palliative  and  perhaps  remedial 
agent  in  the  cases  mentioned,  we  must,  I  think,  believe 
tlmt  the  danger  of  establishing  a  habit  attending  the  prac- 
tice more  than  counterbalances  its  usefulness.  That  the 
prolonged  use  of  opium  in  any  form  is  apt  to  engender 
the  "  opium  habit,''  we  all  know,  and  I  believe  that  of 
all  the  modes  of  administration  tending  to  such  an  end, 
that  of  opium-smoking  is  the  most  potent.  This,  I  think, 
is  exemplified  in  the  graduates  of  the  various  opium  dens 
that  curse  our  land  to-day.  Witness  the  novice  who, 
feeling  a  little  indisposed,  or  it  may  be  for  the  purpose 
of  experiment,  repairs  to  one  of  these  nests  of  degrada- 
tion. Now,  he  does  not  enter  such  with  the  intention  of 
cultivating  a  habit,  and  if  the  possibility  of  such  a  danger 
was  suggested  to  him,  he  would  laugh  at  the  idea.  Yet, 
in  nine  cases  out  of  ten,  when  he  has  finished  his  first 
pipe  he  has  forged  the  first  link  in  the  chain  that  will 
bind  him  a  slave  to  this  powerful  drug.  Nor  does  he 
stop  here  ;  finding  the  effect  so  very  pleasant,  he  re- 
turns again  and  again,  until  the  chain  is  completed  and 
he  is  bound  body  and  soul  to  a  master  that  knows  no 


mercy.  Now,  if  there  is  danger  of  establishing  a  habit  in 
the  man  who,  to  allay  his  indisposition  or  satisfy  his 
curiosity,  inhales  the  fumes  of  opium,  how  much  more 
danger  is  there  to  him  whom  suffering  induces  and  his 
physician  adnses  to  resort  to  it  ?  Why,  a  hundred  times 
more,  I  think,  and  it  seems  to  me  that  the  practice  of 
that  man  has  been  limited  who  can  look  upon  the  dan- 
ger as  being  comparatively  nil.  Perhaps  some  may  say, 
"  We  would  not  sdlow  our  patients  to  go  beyond  a  certain 
limit  of  safety."  Ah,  but  how  are  you  to  know  just  where 
to  place  this  '<  limit  of  safety  ?  "  The  line  of  demarca^ 
tion  is  certainly  not  well  defined,  and  when  once  beyond 
it  all  the  advice  or  moral  suasion  in  the  world  will  not  in- 
duce the  poor  victim  to  desist  in  his  degrading  habit. 
Degrading,  I  say,  because,  contrary  to  the  opinion  of 
Dr.  Thudichum,  I  believe  that  the  "stories  told  of  the  vic- 
tims of  opium-smoking"  are  not  sufficiently  colored. 
They  lack  the  dark  and  dismal  coloring  that  truly  de^ 
scribes  the  wretched  condition  to  which  these  poor  un- 
fortunates descend.  Degrading,  because  it  robs  man  of 
all  his  finer  instincts ;  robs  him  of  his  intellect,  and  makes 
of  him  an  object  of  universal  commiseration. 

I  am  well  aware  that  there  is  nothing  new  or  startling 
in  the  foregoing,  but  as  the  subject  is  one  which  cannot 
be  too  often  referred  to,  and  as  many  men,  especially  the 
younger  members  of  the  profession,  are  prone  to  act  upon 
every  suggestion  brought  to  their  notice,  I  venture  to 
offer  it  as  a  protest  against  the  practice  of  "  opium-smok- 
ing as  a  therapeutic  measure,"  and  I  trust  it  may  not  be 
altogether  unheeded. 

J.  H.  Carman,  M.D. 

South  Ahboy,  N.  J.,  September  33, 1884. 


INTRAVESICAL  INJECTIONS  OF  NITRATE  OF 
SILVER. 

To  THB  £1ditor  of  TkiB  MsDiCAL  Rbcobo. 

Sir  :  At  the  close  of  an  editorial  on  intravesical  injec- 
tions published  in  the  issue  of  The  Record  for  Septem- 
ber 6th,  occurs  the  following:  "Nitrate  of  silver  has 
been  much  used  in  this  country  and  is  still  used  in 
France;  but  the  less  of  that  material  thrown  into  a 
bladder,  so  much  the  better  for  the  patient.'' 

Now,  Mr.  Editor,  will  you  favor  a  large  number  of 
practitioners  who  are  constantly  using  nitrate  of  silver 
injections  (even  the  strongest  solutions,  in  cases  of  cystitis, 
with  the  greatest  benefit)  with  substantial  reasons  for  the 
advice  contained  in  this  extract  from  your  article  ?  Maify 
of  us,  accustomed  to  this  practice,  believe  the  traditional 
fear  of  making  nitrate  of  silver  injections  into  the  bladder 
to  be  wholly  imaginary,  a  veritable  b^e  noire,  as  nothing 
but  good  results  from  their  use  in  our  hands  in  properly 
selected  cases  of  cystitis,  for  which  troublesome  malady 
they  may  be  safely  applied  and  are  often  eminently 
curative  after  every  other  measure  has  signally  failed. 

The  apostle  of  this  practice.  Professor  Richardson,  of 
New  Orleans,  one  of  the  most  conservative,  able,  and 
truthfiil  practitioners  in  our  country,  has  fiilly  demon- 
strated in  his  clinical  lectures  and  private  practice,  the 
best  results  to  be  derived  firom  the  employment  of  strong 
intravesical  injections  of  nitrate  of  silver  in  cases  of 
cystitis,  and  his  statements  are  being  rapidly  endorsed 
by  others  in  the  profession. 

In  the  Philadelphia  Medical  News  of  November  lo, 
1883,  after  a  few  remarks  on  the  treatment  of  vesical 
catarrh,  I  took  occasion  to  report  a  most  aggravated 
and  instructive  case  of  cystitis  treated  successfiilly  by  the 
Richardson  method,  and  referred  to  the  favorable  experi- 
ence of  others  also  who  had  employed  it  more  exten- 
sively. 

The  attention  which  I  then  called  to  the  views  of 
Professor  Richardson  has  induced  many  who,  like  myself, 
were  no  doubt  prejudiced  against  the  method,  to  boldly 
try  it,  and  subsequent  reports,  published  and  by  private 
letters,  are  most  favorable  to  the  practice,  and  confirm 
all  that  has  been  claimed  for  it. 


502 


THE  MEDICAL  RECORD. 


[November  i,  i38^ 


For  instance,  Professor  William  Gardner,  Professor  of 
Gynecology  in  McGill  University,  of  Montreal,  who 
noticed  my  communication  to  the  News^  relates  an 
experience  very  flattering  to  the  method  and  recom- 
mended it  in  his  lectures  to  the  class.  In  gynecological 
cases  especially,  I  venture  to  predict  that  there  is  a 
great  future  awaiting  a  more  extended  and  systematic 
employment  of  the  stronger  nitrate  of  silver  solutions  in 
cases  of  cystitis.  By  such  means,  probably,  operative 
procedures  upon  the  bladder  as  a  dernier  ressort  in  re- 
bellious cases  of  this  malady  may  be  obviated. 

There  are  many  physicians,  in  Texas  at  least,  who, 
relying  on  the  published  statements  of  Professor  Richard- 
son, did  not  hesitate  to  accept  the  clinical  facts  he  en- 
deavored to  impress,  and  are  now  daily  employing  intra- 
vesical  injections  of  nitrate  of  silver  in  their  practice. 
We  have  witnessed  no  such  baneful  results  as  intimated 
by  you.  Indeed,  our  surprise  is  that  the  practice  is  not 
more  generally  appreciated. 

Professor  Richardson's  pathological  views  and  rational 
treatment  of  cystitis  by  strong  intravesical  injections  of 
nitrate  of  silver  were  published  in  the  Medical  News  and 
Abstract  for  1879. 

It  is  my  opinion  that  these  should  be  more  widely 
known  and  acted  upon. 

Very  respectfully, 

Henry  K.  Leake,  M.D, 

Dallas,  TkXAS. 

[We  do  not  see  that  the  success  of  nitrate  of  silver  in- 
jections in  properly  selected  cases  of  cystitis  militates 
against  our  view,  that  the  less  of  it  thrown  into  the  blad- 
der the  better  for  the  patient ;  and  we  were  fully  aware 
of  the  successes  and  teaching  of  Professor  Richardson 
when  we  wrote  the  article  referred  to.  But  there  is  a 
wide  difference  between  "  properly  selected  cases  "  and 
the  indiscriminate  use  of  this  solution,  which  was  a  mat- 
ter of  every-day  practice  a  few  years  ago,  and  is  still  the 
routine  practice  with  some  physicians. 

From  our  "  properly  selected  cases "  we  should  cer- 
tainly exclude  simple  acute  cystitis.  This  point  must 
seem  so  clear  that  we  will  not  discuss  it  But  there  are 
also  cases  of  chronic  cystitis  which  will  be  less  benefited 
by  injections  of  solutions  of  nitrate  of  silver  than  by  other 
treatment  We  do  not  consider  these  injections  advisa- 
ble in  simple  chronic  cystitis.  In  chronic  cystitis  with 
vesical  catarrh  we  have  obtained  excellent  results  with 
the  nitrate  injections ;  and  we  have  also  seen  cases,  and 
others  are  on  record,  in  which  the  effect  of  injections  of 
strong  solutions  of  nitrate  of  silver  were  so  violent  as  to 
cause  very  serious  apprehension  for  the  safety  of  the  pa- 
tient And  in  our  experience,  those  cases  have  done 
best  in  which  weak  solutions  were  first  used,  so  as  to  ac- 
custom the  bladder  to  the  powerful  astringent,  and  then 
the  strength  was  increased  up  to  the  desired  point 

There  is  another  objection  to  the  use  of  very  strong 
solutions  in  many  cases :  they  may  cause  such  a  degree 
of  vesical  tenesmus  that  it  is  absolutely  necessary  to  ad- 
minister large  doses  of  morphia  to  alleviate  the  pain.  In 
these  cases  we  cannot  regard  the  use  of  an  irritant,  at 
least  so  powerful  as  a  strong  solution  of  nitrate  of  silver, 
as  advisable ;  and  much  better  results  are  to  be  expected 
from '  iodoform,  which,  as  Mikulicz  has  pointed  out,  is 
especially  adapted  to  mucous  surfaces ;  or  from  Ktistner's 
method  with  1.5000  solutions  of  corrosive  sublimate 
injected  through  a  funnel-tube.  This  is  especially  adapted 
to  the  treatment  of  chronic  cystitis  in  women.  We  are  very 
much  inclined  to  look  upon  suppurative  cystitis  as  an  af- 
fection which  should  be  treated  as  a  suppurating  cavity 
in  any  other  part  of  the  body ;  but  with  the  disadvantage 
that  we  have  here  a  cavity  into  which  there  is  a  constant 
flow  of  an  irritating  fluid — the  urine;  and  that  more 
favorable  results  would  be  obtained  by  cystotomy  and 
thorough  drainage ;  except  in  women,  where  the  urethra 
is  short  and  can  be  so  widely  dilated  as  to  admit  of  drain- 
age through  it 


We  do  not,  therefore,  unconditionally  condemn  nitrate 
of  silver  solutions ;  we  know  that  they  act  most  excel- 
lently in  "  properly  selected  cases ; "  and  in  the  sentence 
from  our  editorial,  to  which  our  correspondent  refers,  we 
did  not  necessarily  intend  to  convey  the  idea  that  the 
less  quantity  of  the  silver  used  the  better  for  the  patient, 
but  that  the  fewer  cases  in  which  strong  solutions  are 
used  the  better;  the  cases  being,  of  course,  selected. 
We  cannot,  however,  agree  with  our  correspondent  that 
there  is  a  great  future  for  the  stronger  solutions  of  this 
salt  in  gynecological  cases,  but  think  that  the  methods  of 
Kilstner,  already  referred  to,  of  Struppi,  or  of  Fritsch 
and  Jackson  more  rational,  and  more  peculiarly  suited  to 
these  cases.     We  heartily  endorse  the  recommendation 
of  Professor  Richardson  to  inject  a  solution  of  common 
salt  into  the  bladder  when  the  silver  solution  is  too  irri^ 
tating;  and  will  add  that  we  believe  the  salt  solution 
plays  no  unimportant  part  in  the  result,  especially  if  it  be 
a  strong  solution.     It  is  not  at  all  improbable  that  it  de 
lays  the  decomposition  of  the  urine,  which  is  a  chief 
cause  of  the  unhappy  results  in  so  many  cases. 

To  conclude,  we  have  seen,  as  our  correspondent  says, 
cases  cured  by  the  strong  solutions  of  nitrate  of  silver 
when  other  remedies  had  failed ;  and  we  have  also  seen 
a  strong  infusion  of  tea  succeed  when  the  patient  was 
rapidly  going  down  hill  under  the  use  of  the  silver  solu- 
tion. And  when  we  say  that  the  silver  was  aggravating 
the  symptoms,  we  mean  that  the  strong  injections  were 
so  irritating,  and  caused  such  a  degree  of  vesical  tenes- 
mus, that  it  was  necessary  to  narcotize  the  patient  in 
order  to  prevent  what  we  believed  to  be  a  dangerous  de- 
gree of  shock.  If,  however,  the  strong  solution  does  not 
cause  such  phenomena,  we  believe  it  to  be,  in  properly 
selected  cases,  an  excellent  remedy,  and  we  would  not 
hesitate  to  use  it. — Ed.] 


FLORIDA  AS  A  HEALTH  RESORT. 

To  THB  Editor  or  Tub  Mbxxcal  Rbookd. 

Sir  :  In  the  April  26th  number  of  The  Record  appeared 
an  article  on  the  above  subject  by  a  Baltimore  physician. 
I  eagerly  scanned  subsequent  numbers,  expecting  some 
one  with  facile  pen  to  reply,  as  the  views  of  the  writer 
were  very  different  from  those  heretofore  published,  and 
from  those  of  physicians  in  active  practice  in  this  State, 
as  well  as  from  facts  that  can  readily  be  obtained  from 
persons  who  have  been  benefited  or  cured  by  this  climate. 
For  there  are  men  and  women  in  every  section  of  the 
State — from  the  Georgia  line  to  the  extremity  of  the  pen- 
insula, from  the  eastern  coast  that  is  tempered  by  "  that 
river  of  the  ocean,"  the  Gulf  Stream,  to  the  western 
shore  that  is  kissed  by  the  waters  of  the  Gulf  itseU — ^who 
bless  this  "land  of  fruits  and  flowers,''  who  speak  in 
glowing  terms  of  the  climate  that  has  transformed  disease 
into  health,  and  has  changed  the  hectic  flush  to  the 
"peach-bloom  hue."  Is  it  strange  that  one  who  has 
spent  night  affer  night  in  sleeplessness  and  pain,  racked 
with  cough  and  annoyed  with  expectoration,  debilitated 
and  enfeebled  by  months  of  sickness ;  and  has  had  all 
this  changed  to  nightly  sleep,  as  sweet  and  refreshing  as 
an  infant's,  the  cough  allayed,  the  appetite  improved,  the 
health  regained — is  it  strange,  I  repeat,  that  such  a  one 
should  speak  in  vindication  of  the  sunny  clime  that  has 
thus  benefited  him  ?  Can  the  physician  who  has  seen 
these  changes  occur  be  expected  to  seal  his  lips  and 
tacitly  admit  that  the  climate  of  Florida  is  unsuited  to 
diseases  of  the  respiratory  organs  ?  There  is  scarcely  a 
physician  in  the  State  who  would  not  deny  such  a  chai]g^ 
and  prove  it  untrue  by  patients  who  are  or  had  been 
under  his  care. 

In  the  article  referred  to,  it  is  admitted  that  this  cli- 
mate is  adapted  to  cases  of  rheumatism,  chronic  neuralgia, 
syphilis,  and  gout.  We  claim  that  the  list  of  diseases 
that  will  be  benefited  or  cured  in  this  climate  can  be 


November  i,  1884.] 


THE  MEDICAL  RECORD. 


503 


considerably  lengthened.  And  as  physicians  we  not  only 
claim  it,  but  can  prove  it  by  incontestable  evidence.  A 
complete  list,  or  a  catalogue  of  the  varieties  of  diseases, 
will  not  be  attempted,  but  the  kinds  of  diseases  that 
experience  has  shown  the  climate  of  Florida  most  adapted 
for  will  be  given.  They  are  :  Tuberculosis  in  which  the 
deposit  is  incipient  or  limited,  bronchitis,  laryngitis,  nasal 
and  pharyngeal  catarrh,  asthma,  nervous  complaints,  re- 
mits of  overwork,  and  chronic  uterine  troubles  resulting 
from  congestions.  Those  aged  and  invalid  persons  who, 
after  battling  with  the  storms  of  life  and  the  rigorous 
winters  of  the  North,  now  need  warmth  and  rest  and  re- 
laxation, enjoy  our  genial  sunshine  and  rejuvenating  at- 
mosphere. There  is  a  peculiar  soothing,  rest-giving 
quality  of  the  atmosphere,  which  especially  adapts  it  to 
Aose  who  are  overworked  and  jaded,  or  of  a  nervous 
character.  Before  they  have  been  here  many  days  they 
get  the  refreshing  sleep  that  has  been  absent  so  long.  No- 
where in  our  whole  broad  land  can  such  a  man  or  woman 
so  quickly  get  relief  as  here. 

Although  the  annual  rainfall  is  large  (as  it  should  be 
on  this  sandy  soil),  yet  the  winter  months  are  of  the  dry 
season.  And  although  we  have  some  rain  at  this  time, 
there  are  very  few  days  that  the  invalid  cannot  spend  a 
portion  of  in  the  open  air. 

As  to  humidity,  this  city  will  compare  fiEivorably  with 
other  places.  It  is  less  here  than  at  other  Florida  sta- 
tions of  the  Signal  Service  on  the  Gulf  coast  The 
courteous  and  efficient  officer  at  this  station.  Sergeant 
Smith,  has  placed  his  records  at  my  disposal.  (1  would 
state  here  that  he  published  in  the  April  4th  number  of  the 
Daily  Times-Uhion  of  this  city  an  abstract  of  the  mete- 
orological observations  at  this  station,  covering  a  period 
of  twelve  years,  which  would  be  of  interest  to  many.) 
I  copy  sufficient  for  comparison  from  the  last  reports 
published  from  all  stations  : 

Monthly  Mban  Humidity. 


December, 
1879. 

January, 
z88o. 

February, 
188a. 

March, 
1880. 

"St' 

Jacksonville,  Fla. 
Los  Angeles,  CaL 
Detroit,  Mich.  . . 
New  York,  N.  Y. 

77.6 

67.9 
82.1 

73.4 

77.1 
65.0 

79.8 
73.3 

69.4 
67.0 

75.1 

73-0 

63.7 

72.6 
69.6 
70.2 

63.0 
77.4 
65.9 
61.0 

If  space  permitted  I  could  introduce  reports  to  show 
that  the  changes  from  warm  to  cold  are  not  great  or  fre- 
quent. Northers,  in  the  Texas  acceptation  of  the  term, 
do  not  occur  here.  Of  course,  when  there  is  an  ex- 
tremely cold  winter  in  the  North,  like  the  last,  we  have 
a  little  colder  weather  here  than  the  ordinary  season. 
\t  is  aboat  fifteen  miles  on  an  air-line  to  the  Atlantic, 
hence  the  air  is  never  too  highly  impregnated  with  salt 
or  too  **  bracing."  It  would  be  hard  to  find  a  more 
equable  and  pleasant  climate,  and  at  the  same  time  have 
all]  the  advantages  of  congenial  companionship  and 
the  higher  civilization.  During  the  fall,  winter,  and 
spring  months  the  State  is  filled  with  invalids,  pleasure- 
seekers,  and  those  seeking  investment,  firom  the  more 
northern,  and  I  might  say  from  every  State  and  Territory, 
as  well  as  from  Europe.  It  has  many  advantages  and  a 
grand  future.  Improvement  is  the  watch-word  of  the 
day.  It  is  rapidly  filling  up  with  the  best  class  of  ac- 
tual settlers.  It  is  too  late  for  derogatory  writers  to  curb 
her  onward  march  or  still  her  reputation  as  a  health  re- 
sort. 

I  intended  speaking  of  the  great  number  of  deaths  of 
consumptives  that  was  said  to  occur  at  Gainesville.  But  I 
have  just  received  the  July  19th  number  of  The  Record 
containing  an  article  on  that  point  by  Dr.  Bradner.  My 
evidence  would  simply  corroborate  his. 
Yours  respectfiilly, 

E.  M.  Nolan,  M.D. 

jAaUONVXLLSf'jFLA.,  Julyl34, 1884. 


A  CASE  OF  HAY-FEVER  IN  AN  INFANT. 

To  THB  Editor  op  Tm  Mbdical  Rkc(»d. 

Sir  :  On  the  night  of  September  23,  1884,  I  was  called 

to  attend  Mrs.  P ,  in  her  confinement.     The  labor 

terminated  without  anything  unusual  occurring  to  the 
mother.  At  the  time  she  was  confined  she  was  suffering 
from  a  severe  cold.  When  the  child  (a  male)  was  born 
it  gave  a  cry  and  stopped  breathing.  As  it  became 
purple  I  cut  the  cord  as  quickly  as  possible,  and  after 
rolling  it  from  side  to  side  and  using  nitrite  of  amyl  it 
began  to  breathe  with  difficulty,  as  though  something  was 
in  the  windpipe.  The  eyes  were  inflamed  and  were 
opened  only  for  a  moment  at  a  time,  and  its  nose  was 
discharging.  The  child  was  plump  and  well  nourished 
and  did  not  seem  to  have  any  difficulty  in  swallowing. 
I  gave  it  a  drop  of  whiskey  in  warm  water  every  ten 
minutes,  which  revived  it  considerably,  but  it  had  to  be 
watched  and  I  worked  for  an  hour  with  it.  I  gave  it  mi- 
nute doses  of  tartrate  of  antimony  which  gave  it  some  re- 
lieC  Its  greatest  difficulty  was  in  living  between  9  p.m. 
and  3  A.M. ;  about  4  A.M.  it  would  begin  to  breathe  easier 
and  would  be  comparatively  easy  during  the  day.  I 
then  gave  it  a  prescription  containing  fluid  extract  of 
squills  compound,  paregoric,  and  chlorate  of  potassa, 
which  gave  it  some  relief  but  matters  continued  about 
the  same,  being  good  during  the  day  and  nursing  well  but 
having  the  trouble  at  night.  October  7  th  I  gave  it  the 
following  mixture :     . 

5.  Sodic  bromidi 3  j. 

Tinct  lobellue gtt.  x. 

Tinct.  opii gtt.  iv. 

Aquae f|^. 

M.  Sig. — ^Teaspoonful  at  8  p.m.  and  repeat  in  two 
hours  if  necessary. 

That  night  it  slept  without  any  trouble  and  has  been 
all  right  ever  since.  On  the  night  of  the  7th  we  had  a 
frost  and  the  day  was  cold.  The  case  is  very  interesting 
on  account  of  the  age  of  the  patient.  The  mother  was 
Scotch  and  the  father  a  Dane.  There  is  no  history  of 
asthma  or  hay-fever  in  the  family.  If  it  was  not  hay 
asthma  what  was  it?  I  do  not  think  the  medicine 
cured  the  little  patient,  and  the  symptoms  and  termina- 
tion of  the  case  are  very  suggestive. 
Very  truly  yours, 

S.  B.  Spbrry,  M.D. 

TWO     CASES    OF     TRAUMATIC    DIAPHRAG- 
MATIC   HERNIA. 

To  ram.  Editoh  or  Tvm  Mbhcai.  RgooKP. 

Sir  :  The  cases  reported  in  your  issue  of  October  nth 
by  Drs.  Kortright  and  Harris  suggest  the  publication  of 
the  following  cases,  as  they  present  many  points  of  simi- 
larity. They  came  under  my  observation  while  an  in- 
teme  in  Bellevue  Hospital,  and  have  not  been  before 
published. 

Case  I. — ^A  stout  laborer,  aged  forty-three,  was  ad- 
mitted to  Ward  30,  April  27,  1881.  The  history  given 
was  that  he  had  been  beating  carpets  upon  a  roof  when 
a  chimney  near  toppled  and  fell,  burying  him  beneath 
the  debris.  He  was  thrown  forward  upon  his  abdomen, 
the  bricks  fisdling  upon  his  back.  He  said  the  daeces 
''were  crushed  out  of  him."  When  examined  at  the 
hospital  he  was  suffering  slightly  from  shock.  Simple 
firactures  of  the  tibia  and  fibula  and  of  the  fourth  rib  left 
side  were  found  There  were  marks  of  contusion  over  the 
chest  and  abdomen.  Great  pain  about  the  sacral  region 
was  complained  of,  making  it  impossible  for  him  to  sit  up» 

For  two  days  all  went  well  except  that  the  bowels 
were  obstinately  constipated.  Persistent  vomiting  then 
set  in,  with  considerable  tympanites,  but  no  pain  or  ab- 
dominal tenderness  were  found.  The  pulse  became  rapid 
and  feeble,  although  the  temperature  remained  nonnaL 
The  case  was  seen  by  several  members  of  the  visiting 
staff  and  the  diagnosis  of  rupture  of  the  intestine  or  a 


/ 


504 


THE   MEDICAL  RECORD. 


[November  i,  1884. 


paralysis  from  contusion  suggested.     A  displacement  of 
the  heart's  apex  to  the  right  was  noticed. 

Early  May  2d  the  patient  went  into  collapse  and  died 
quite  suddenly.  The  vomiting  had  continued  at  inter- 
vals but  did  not  become  stercoraceous.  The  bowels  re- 
mained obstinately  constipated.  The  patient  complained 
at  times  of  dyspnoea.  The  autopsy  was  made  twenty- 
four  hours  after  death. 

Upon  opening  the  thorax  the  left  chest  seemed  nearly 
filled  with  coils  of  intestine  which  extended  upward  as 
high  as  the  third  rib.  The  heart's  apex  was  displaced  up- 
ward and  to  the  median  line.  The  viscera  of  thorax  and 
abdomen  were  removed  together.  A  rupture  of  the  left 
leaflet  of  the  diaphragm  was  found  nearly  four  inches 
long,  nearer  its  posterior  than  its  anterior  border. 
Through  this  opening  had  passed  about  four  feet  of  small 
intestine  and  several  inches  of  the  transverse  colon.  The 
intestine  showed  no  evidence  of  strangulation  ;  it  was 
not  even  congested,  but  like  the  part  remaining  in  the 
abdomen  it  was  distended  with  gas.  The  left  lung  was 
compressed  into  a  mass  about  the  size  of  a  foetal  head. 
The  right  lung  showed  slight  oedema.  The  heart  was 
normal  There  was  no  evidence  of  pericarditis,  pleurisy, 
or  peritonitis.  No  external  evidence  of  injury  to  liver, 
spleen,  or  kidneys.  Considerable  extravasated  blood  was 
found  in  the  substance  of  the  abdominal  muscles  and  be- 
neath them.  A  separation  of  the  symphysis  pubis  of  one 
inch  was  found,  also  of  half  an  inch  at  the  sacro-ilial 
articulation.  The  ligaments  at  both  joints  were  ruptured 
but  there  was  no  fracture. 

In  this  case  the  chest  was  never  carefully  examined  ; 
the  pain  which  was  often  complained  of  was  referred  to 
the  fractured  rib#  The  tympanitic  percussion,  the  dis- 
placement of  the  heart  and  absence  of  breathing  over  the 
left  chest  in  front,  even  had  they  been  made  out,  would 
have  found  their  most  natural  explanation  in  a  pneumo- 
thorax also  caused  by  the  costal  injury. 

Case  II.  occurred  in  the  service  of  the  late  Dr.  James 
R.  Wood.  The  patient,  a  man  about  forty  years  old,  was 
admitted  to  the  hospital  for  a  compound  fracture  of  the 
left  elbow,  produced,  it  was  reported,  by  a  fall  of  forty 
feet  from  a  building.  The  patient  was  in  fair  condition, 
and  nothing  in  his  appearance  suggested  serious  internal 
injuries.  On  the  following  day  the  elbow  was  exsected 
by  Dr.  Wildman,  the  house  surgeon.  Very  little  blood 
was  lost  during  the  operation  but  the  patient  never  rallied 
from  it.  He  sank  steadily  and  died  in  collapse  fourteen 
hours  after  the  operation  and  forty  hours  after  the  injury. 

On  opening  the  thorax  a  large  mass  was  found  project- 
ing into  it  on  the  left  side,  which  on  examination  was 
found  made  up  of  the  stomach,  much  distended,  the  pan- 
creas, the  spleen,  and  about  a  foot  of  the  transverse  colon. 
These  viscera  about  half  filled  the  chest,  crowding  the 
heart  to  the  right  and  the  lung  upward  and  backward. 
None  of  the  displaced  viscera  bore  evidence  of  any  spe- 
cial violence  or  of  any  strangulation.  Considerable  extra- 
vasated blood  was  found  in  the  substance  of  the  abdom- 
inal walls  and  in  the  pelvic  cavity. 

An  examination  of  the  diaphragm  showed  a  rupture 
three  inches  long  in  the  muscular  substance  of  the  left 
leaflet,  extending  from  the  margin  of  the  tendinous  por- 
tion outward  to  within  an  inch  of  its  border. 

This  specimen  is  now  in  the  Bellevue  Hospital  Mu- 
seum. L.  Emmett  Holt,  M.D. 

33  Pajuc  Avbnub,  New  York. 


DEATH    FROM    THE    INTRODUCTION    OF    A 
STOMACH-TUBE. 

To  THK  Editor  op  Tub  Medical  Rbooro. 

Sir:  An  unmarried  woman,  aged  twenty-seven,  with 
a  history  of  chronic  gastritis,  was  being  treated  by  Dr. 
B ,  an  itinerant  doctor,  by  introducing  a  stomach- 
tube  into  the  stomach  and  removing  the  contents — after- 
ward washing  out  the  organ.  The  operation  had  been 
performed  twice  successfully.  At  the  third  attempt  he 
claimed  to  have  passed  the  tube  into  the  stomach,  when 


she  fell  back  and  immediately  expired.  I  was  present  at 
the  autopsy.  The  stomach  was  dilated  considerably 
and  in  an  advanced  stage  of  chronic  inflanmiation.  Na- 
merous  spots  of  ecchymosis  were  present  The  heart 
was  pale,  and  there  was  fatty  inflltration«  No  other 
organic  changes  were  noticed.  The  remainder  of  the  ali- 
mentary canal  was  healthy,  as  were  the  liver,  spleen,  and 
kidneys.  She  probably  died  from  paralysis  of  the  heart 
from  the  shock  of  the  operation.  No  coroner's  inquest 
was  held.  This  case  may  serve  as  a  warning  as  to  what 
might  happen  in  any  trivial  operation  upon  a  patient  with 
a  weak  and  fatty  heart.  A.  D.  Bundy,  M.D. 

St.  Ansgax,  Ia.,  September  30, 1884. 


THE  AVOWED  OBJECT  OF  THE  NEW  YORK 
STATE  MEDICAL  ASSOCIATION. 

To  the  Editok  op  The  Hmdical  Rbookix 

Sir  :  In  your  editorial  note  concerning  the  New  York 
State  Medical  Association,  you  say :  **  The  main  object 
of  the  Association  is  to  secure  to  the  profession  in  New 
York  State  representation  in  the  American  Medical  Asso- 
ciation." Did  not  the  latter  association,  at  its  meeting 
in  Washington  last  June,  throw  open  its  representation 
to  every  respectable  physician  who  accepted  its  code  or 
paid  Ave  dollars  ?  It  appears  to  me  that  if  the  sum  in 
question  will  secure  personal  representation,  it  is  hardly 
necessary  to  become  a  member  of  the  New  York  State 
Medical  Association  for  the  purpose  stated. 

You  further  say :  "The  question  will,  therefore,  doubt- 
less be  raised  whether  those  counties  in  which  medical 
societies  have  not  changed  their  old  code,  and  which  are 
still  entitled  to  representation,  can  send  a  double  set'^ 
The  true  position  of  these  societies  is  this  :  The  action 
of  the  State  Society  has  rendered  the  old  code  void  in 
every  county  society  in  the  State,  so  far  as  the  power  to 
discipline  is  concerned.  Those  societies,  therefore,  which 
have  not  formally  adopted  the  new  code  are  practically 
without  any  at  all ;  they  are  in  fact  ruh-coders.  To  this 
complexion  have  they  come  at  last.  Junivs. 

Official  List  €f  Changis  in  th$  Statums  ondDuHu  cf  Offiun 

urving  in  ths  Midical  Dtpartnunt^  United  SiaUs  Armjf^ 

from  October  19  to  October  25,  1884* 

Alden,  Charles  H.,  Major  and  Surgeon.  Relieved 
from  duty  at  Fort  Yates,  D.  T.,  and  ordered  for  duty  at 
Fort  Snelling,  Minn.  S.  O.  125,  Department  of  Dakota, 
October  20,  1884. 

ViCKERY,  R.  S.,  Major  and  Surgeon.  In  addition  to 
his  other  duties  will  assume  charge  of  the  ofl&ce  of  the 
Medical  Director  during  temporary  absence  of  Major  J. 
C.  McKee,  Surgeon  U.S.' A.,  Medical  Director  of  the 
Department.  G.  O.  34,  Headquarters  Department  of 
California,  October  8,  1884. 

WiNNE,  C.  K.,  Captain  and  Assistant  Surgeon.  In 
addition  to  his  duties  as  Post  Surgeon  at  Benicia  Bar- 
racks, will  also  attend  the  sick  at  Benicia  Arsenal  Gal. 
S.  O.  122,  Headquarters  Dep't  of  Cal.,  Oct.  13,  1884, 

Strong,  Norton,  First  Lieutenant  and  Assistant  Sur- 
geon. Assigned  to  duty  at  Fort  Union,  N.  M.  S.  0. 
198,  Department  of  Missouri,  October  4,  1884. 

Phillips,  John  L.,  First  Lieutenant  and  Assistant 
Surgeon.  Transferred  from  Department  of  the  East  to 
Department  of  Dakota.  S.  O.  245,  A.  G.  O.,  October 
18,  1884.  

Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  October  ^^^  1884. 

Bloodgood,  Delavan.  Promoted  to  the  grade  of 
Medical  Director,  August  22,  1884. 

Oberly,  Aaron  S.  Promoted  to  the  grade  of  Medi- 
cal Inspector,  March  28,  1884. 

Wells,  Henry  M.  Promoted  to  the'grade  of  Medi- 
cal Inspector,  August  22,  1884. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  19 


New  York,  November  8,  1884 


Whole  No.  731 


©riglual  %xXXt\ts. 


CIRRHOSIS   OF  THE  PANCREAS. 
By  CHARLES  WARRINGTON  KARLE,  M.D., 

raOKKSSOR  OP  OBSTETRICS,  COLLKGR  OF  PHYSICIANS  AND  5URGSONS  ;   AND  OP  DIS- 
BASfS  OP  CHILDRBN,   WOMAN'S  MBDICAL  COLLHCB,   CHICAGO,  ILL. 

The  occurrence  of  four  cases  of  chronic  inflammation  of 
the  pancreas  in  private  practice,  within  the  space  of  three 
jears,  has  led  me  to  review  the  literature  on  the  subject 
with  more  than  ordinary  care. 

That  diseases  of  this  organ  are  rare  is  undoubtedly 
true  ;  but  it  is  also  a  fact  that  comparatively  little  atten- 
tion, up  to  this  time,  has  been  given  to  their  investiga- 
tion and  study. 

Bartholow  says  that  so  little  is  definitely  known  of  dis- 
eases of  the  pancreas,  that  many  systematic  works  omit 
the  subject  entirely.  Atkin,  in  his  large  work,  does  not 
speak  of  disease  of  this  organ.  Hartshorn,  editing  Wat- 
son, devotes  about  fifteen  lines  to  the  consideration  of 
this  subject.  Flint  and  Wood  have  only  short  articles, 
and  Da  Costa  has  collected  the  history  of  but  forty-five 
cases,  upon  which  he  bases  the  brief  remarks  made  in 
his  work  on  diagnosis.  One  may  look  through  scores  of 
journals  without  finding  an  allusion  to  diseases  of  the 
pancreas. 

For  anything  like  a  comprehensive  article,  we  are 
obliged  to  go  to  Ziemssen,  and  here  we  are  met  by  the 
statement  that  the  ^reat  rarity  of  these  diseases  has  hin- 
dered the  more  rapid  development  of  our  knowledge  of 
the  bearings  and  pathological  changes  in  the  organ. 

It  will  go  without  saying  that  in  the  living  or  dead 
we  neglect  to  examine  this  organ  as  we  should ;  and  for 
obvious  reasons,  however  rare  or  frequent  diseases  of  the 
pancreas  may  be,  their  diagnosis  will  remain  obscure, 
and  in  the  hurry  of  the  post-mortem,  often  necessary,  the 
gross  appearance  of  the  abdominal  salivary  gland  will 
not  be  considered,  and  in  many  cases  the  organ  will  not 
be  found. 

Case  I. — Edward  E ,  aged  sixty-five,  American, 

contractor  and  builder.  Was  seen  first  November,  1880. 
Previous  to  this  sickness  he  had  never  needed  the  ser- 
vice of  a  physician,  and  had  always  led  a  very  active  life. 
During  the  early  part  of  the  year  he  commenced  to  ema- 
ciate, and  applying  to  a  neighboring  physician  was  given 
some  medicine  for  malaria.  He  was  not  relieved,  but 
.was  able  to  transact  business.  Throughout  the  summer 
months  his  appetite  had  changed  greatly,  and  he  had  no 
desire  for  meats,  but  relished  milk,  mush,  etc. 

At  my  first  visit  I  noticed  his  white  anaemic  appear- 
ance, and  obtained  the  following  personal  history :  His 
ancestry  were  long  lived,  and  he  had  never  had  syphilis. 
There  was  nothing  abnormal  as  regards  his  nervous  sys- 
tem. His  mental  faculties  were  all  good,  and  he  only 
complained  of  a  roaring  in  his  head  and  ears.  His 
lungs  were  without  a  trace  of  disease,  but  he  was  short 
of  breath  on  account  of  weakness.  The  heart  performed 
its  functions  perfectly,  but  there  was  heard  a  slight  anae- 
mic murmur.  There  was  nothing  abnormal  in  any  of  the 
abdominal  organs,  as  far  as  I  was  able  to  examine  them, 
and  neither  albumen  nor  sugar  was  found  in  his  urine. 
His  passages  from  the  bowels  were  black  and  thin,  with 
occasionally  little  lumps  of  blood  and  mucus.  His 
pulse  was  100;  temperature,  normal.  The  tongue  per- 
fectly clean,  but,  with  mucous  surfaces  and  integument, 


was  almost  white;  indeed,  this  was  his  most  striking 
symptom.  He  looked  jaundiced,  but  a  close  exami- 
nation showed  it  to  be  a  whiteness  of  the  tissues.  The 
only  painful  spot  on  his  entire  body  was  at  the  epigas- 
trium, and  that  was  not  severe  and  only  produced  by 
pressure.  He  complained  of  thirst  and  was  occasionally 
nauseated. 

I  was  unable  to  diagnosticate  the  case,  but  believed 
that  he  was  suffering  from  some  disease  of  nutrition  ;  ex- 
actly the  organ  affected  I  was  not  able  to  determine. 

I  treated  him  for  a  few  days  with  tonics,  mineral  acids, 
strychnia,  and  a  generous  diet.  There  was  no  improve- 
ment, however,  and  Dr.  N.  S.  Davis  saw  him  with  me  in 
consultation. 

We  did  not  attempt  to  name  the  disease,  but  con- 
cluded that  somewhere  in  the  line  of  lymphatics  or  in 
some  part  of  the  digestive  apparatus,  there  was  a  very 
serious  disorder,  which  in  all  probability  would  cause  his 
death.  He  died  one  month  af\er  I  made  my  first  visit, 
having,  however,  passed  into  the  hands  of  another  pro- 
fessional gentleman. 

In  company  with  this  gentleman  I  made  the  post- 
mortem. There  was  nothing  unusual  to  be  seen  in  any 
of  the  principal  organs  ot  his  body,  excepting  the  very 
marked  whiteness  of  all  the  tissues,  and  not  until  I  had 
removed  nearly  the  entire  viscera  of  the  abdomen  and 
came  down  upon  a  white  indurated  pancreas  did  I  find 
the  seat  of  disease. 

The  gross  and  microscopical  appearance  of  this  or^an 
are  given  by  Dr.  S.  J.  Holmes,  I^ecturer  on  Pathological 
Histology  at  Rush  Medical  College  :  "  Pancreas  con- 
tracted ;  consistency  abnormal ;  fibrous  to  the  touch ; 
color  white.  Under  the  microscope  the  connective  tissue 
is  extensively  augmented,  and  there  is  obliteration  of 
certain  glandular  vesicles,  and  atrophy  of  others,  induced 
by  the  pressure  of  the  new-formed  connective  tissue  as 
it  contracted  in  its  maturity.  There  was  slight  fatty  de- 
generation of  the  parenchyma  of  the  kidney." 

Case  II. — Mr.  S.  K.  R ,  aged  fifty-seven,  American. 

This  gentleman,  who  had  been  connected  with  the  print- 
ing and  publishing  establishments  of  this  city  for  years, 
was  first  seen,  professionally,  January,  1882. 

He  was  known  among  his  associates  as  a  most  power- 
ful and  healthy  man,  though  two  years  ago  he  com- 
menced to  fail  in  strength — yet  up  to  within  two  months 
of  his  death  he  continued  to  transact  business. 

I  learned  at  my  first  visit  that  about  twelve  years  ago 
he  had  an  extensive  eczema,  and  has  always  been  a 
dyspeptic.  He  has  also  been  troubled  with  hemorrhoids, 
and  even  now  every  passage  is  attended  with  very  great 
pain  and  some  blood  escapes.  He  has  lost  about  sixty 
pounds.  The  color  of  his  skin  is  very  white,  almost 
yellow,  and  yet  the  conjunctiva  is  perfectly  white. 

His  pulse,  respiration,  and  temperature  are  perfectly 
natural.  He  complains  principally  of  pain  in  the  rec- 
tum, and  a  slight  sickness  at  his  stomach  when  food  is 
taken.  He  has  also  a  feeling  of  weariness,  and  a  con- 
sciousness that  he  is  continually  losing  flesh.  He  does 
not  like  meat  of  any  kind,  or  eggs. 

He  has  been  under  the  care  of  several  physicians,  who, 
in  the  main,  have  promised  a  cure.  It  was  diagnosticated 
by  one  as  a  <<  severe  physical  and  nervous  prostration." 

During  the  first  months  I  treated  him  with  pancrea- 
tine, pepsin,  and  the  mineral  acids,  and  at  a  visit  made 
February  6th  he  claims  that  he  has  gained  three  pounds. 
He  is  having,  however,  alternate  diarrhoea  and  constipa- 


5o6 


THE   MEDICAL  RECORD. 


[November  8, 1884, 


tion.  His  color  is  no  better,  but  he  does  not  complain 
of  quite  as  much  pain  on  the  passage  of  his  bowels. 
During  all  this  time  his  pulse  and  temperature  is  natural. 
The  pulse,  if  anything,  is  a  trifle  slow  and  without 
volume. 

About  this  time,  in  a  conversation  with  him,  he  asked 
me  the  direct  question,  and  pressed  me  for  an  answer,  as  to 
whether  I  could  assure  him  of  a  cure.  After  considerable 
hesitancy,  and  only  after  repeated  solicitations  upon  his 
part,  I  told  him  that  I  was  very  much  afraid  that  he  had 
some  disease  that  would  ultimately  cause  his  death.  That 
was  the  last  time  I  prescribed  for  him. 

June  26th  I  made  him  an  unprofessional  visit.  He 
was  now  being  treated  by  rubbing,  and  was  assured  that 
in  the  course  of  a  few  days  he  would  be  greatly  improved. 
His  pulse  was  78,  temperature  only  97^°,  appetite 
poor.  His  bowel  difficulty  was  entirely  removed,  and  the 
pain  which  he  formerly  experienced  had  ceased.  He 
ascribes  the  cure  of  this  particular  symptom  to  a  root 
syrup  with  molasses  injections.  All  the  pain  and  soreness 
which  he  now  feels  is  just  below  the  ensiform  cartilage. 

He  is  expectorating  a  large,  amount  of  mucus,  and 
has  at  various  times  vomited  something  which  his  attend- 
ants described  as  looking  like  fat.  About  two  weeks 
previous  to  this  visit  he  vomited  a  large  amount  of 
coagulated  blood,  the  hemorrhage  continuing  for  some 
eight  hours,  and  the  quantity  escaping  was  estimated  to 
have  been  about  two  pints ;  of  course,  it  was  mixed  with 
saliva  and  other  secretions. 

At  this  visit  it  appeared  to  me  that  he  was  certainly 
failing,  and  that  a  mortal  result  was  liable  to  take  place  at 
any  time.  He  was  still  hopeful,  however,  and  was  en- 
couraged by  his  attendants.     He  died  June  30th. 

In  the  presence  of  Drs.  R.  N.  Foster,  Cashman,  Mr.  J. 
D.  Waller,  and  the  writer,  Drs.  Graham  and  Haven  made 
the  autopsy.  In  compliance  with  the  wishes  of  the  friends, 
the  abdomen  only  was  opened.  There  was  considerable 
fat  between  the  integument  and  the  abdominal  muscles, 
but  nothing  abnormal  as  regards  the  position  of  any  of 
the  viscera. 

The  whiteness  of  the  tissues,  so  marked  at  the  autopsy  of 
Mr.  E ,  was  also  present  in  this  case.  With  this  excep- 
tion nothing  pathological  was  found  until  the  pancreas 
was  reached.  This  organ  was  hard  and  slightly  enlarged, 
and  filled  with  spots  plainly  seen  with  the  eye.  The 
bowel  was  perhaps  contracted  in  its  calibre  in  some 
places,  but  in  the  rectum,  where  so  much  pain  was  ex- 
perienced up  to  a  short  time  before  his  death,  there  was 
absolutely  no  trace  of  disease. 

There  was  no  abrasion  in  the  continuity  of  the  mucous 
membrane  of  the  stomach,  and  the  haematemesis,  which 
was  so  profuse  a  few  days  before  his  death,  was  probably 
caused  by  pressure  of  the  enlarged  head  of  the  pancreas 
on  some  blood-vessel,  or  it  may  have  been  from  minute 
capillaries  in  the  mucous  membrane  of  the  stomach  which 
could  not  be  discovered  with  the  eye.  The  microscopical 
•examination  was  made  by  Professor  Marie  J.  Mergler, 
and  resulted  as  follows  :  *'  The  pancreas  measured  nine 
inches  in  length,  two  and  one-half  in  breadth  at  the  head, 
two  at  the  tail,  and  was  one  inch  in  thickness.  The  whole 
organ  was  denser  than  normal,  and  its  surface  presented 
numerous  yellowish-white  spots  from  one-fourth  to  one- 
half  inch  in  diameter.  These  light  portions  were  con- 
siderably denser  than  the  rest  of  the  organ.  On  micro- 
scopic examination  there  was  found  increased  amount 
of  connective  tissue  throughout  the  organ,  especially  in 
the  light-colored  portions." 

Case  III. — Mrs.  R ,  aged  ^6,  American ;  housewife. 

Suffered  with  most  terrible  nausea  and  vomiting  during 
the  first  three  months  of  pregnancy.  Seen  in  consultation 
with  Dr.  Haven.  Died  from  exhaustion.  Microscopical 
changes  furnished  by  Professor  Mergler,  and  correspond 
in  every  particular  with  the  others. 

Case  IV. — Mrs.  G.  R ,  aged  25,  American ;  house- 
wife. Passed  through  her  first  pregnancy  and  was  safely 
<lelivered      Made  a  good  recovery.     Six  weeks  after 


commenced  to  cough,  which  persisted  three  or  four  weeks 
Then  a  diarrhoea  with  great  emaciation  troubled  her  four 
months.  During  this  time  emaciation  and  whiteness 
of  tissues  were  the  most  prominent  symptoms.  Died  of 
exhaustion.  The  pancreas  was  hardened,  connective 
tissue  increased,  glandular  tissue  obliterated. 

Physiology, — In  considering  the  diseases  of  an  organ 
the  function  of  which  we  at  best  are  not  particularly  well 
informed  of,  it  may  be  well  for  us  to  study  its  physioW 
That  the  pancreas  is  a  racemose  gland,  and  lies  crosswise* 
behind  the  stomach  and  the  left  lobe  of  the  liver,  and  is 
supplied  with  blood-vessels  and  excretory  ducts,  is  well 
known.     Some  questions  are  pending  as  regards  its  min- 
ute  structure,  but,  on  the  whole,  it  is  not  unlike  the  other 
salivary  glands.     It  is  fairly  settled  now  that  it  has  a 
most  important  part  to  perform  in  the  digestion  of  not 
only  fats,  but  all  kinds  of  food.     It  acts  upon  starch, 
upon  albuminoid  materials,  and  also  upon  the  fats.  l\s 
power  of  converting  starch  into  sugar  is  greater  than  that 
of  the  other  salivary  glands,  and  about  all  that  may  be  said 
concerning  the  saliva  may  be  repeated  in  regard  to  the 
product  of  this  gland.     Its  power  of  digesting  albuminoid 
compounds,  as  well  as  emulsifying  neutral  fats,  has  been 
fully  demonstrated  by  a  large  number  of  physiologists. 
While  the  bile  possesses  nearly  the  same  power,  in  all 
probability  the  complete  digestion  of  fat  is  only  perfected 
by  the  combination  of  the  juices  of  these  two  organs,  the 
liver  and  the  pancreas. 

Pathology  of  the  pancreas, — "  On  account  of  the  slight 
pathological  importance  of  the  pancreas,  only  the  most 
important  changes  which  occur  in  the  glandular  tissue  or 
the  ducts  will  be  considered."  '  And  yet  four  cases  have 
died  in  my  practice  in  four  years  from  inflammation  of 
this  organ.  The  above  quotation  simply  illustrates  what 
I  have  already  remarked,  that  the  pancreas  has  not  been 
studied  as  other  less  important  organs  have. 

In  addition  to  what  I  shall  have  to  say  in  regard  to  the 
pathological  appearances  found  in  my  cases,  I  desire  to 
recapitulate  what  Rokitansky  presents  in  regard  to  the 
abnormities  and  pathological  conditions  of  the  pancreas. 
In  the  first  place,  it  may  be  absent ;  sometimes  only  par- 
tially developed,  and  the  thyroid  and  thymus  glands,  widi 
the  pancreas,  have  been  found  in  one  mass  ;  the  gland 
may  be  enlarged  simply  from  ordinary  induration.  It  is 
diminished  in  size  sometimes  in  persons  of  an  advanced 
age,  and  sometimes,  too,  from  chronic  inflammation  and 
adipose  infiltration.  There  may  be  induration  with  en- 
largement,  or  extreme  softening  with  relaxation  and  suc- 
culence of  the  tissue.  Inflammations  of  this  organ  are 
either  acute  or  chronic,  and  are  either  primary  or  second* 
ary.  When  secondary,  usually  it  is  metastatic.  In  the 
acute  forms  of  inflammation  the  gland  is  found  reddened, 
congested,  and  relaxed  ;  there  is  acute  infiltration  of  the 
interstitial  and  cellular  tissue.  In  the  chronic  inflamma- 
tion there  is  hardening  of  the  cellular  tissue  and  obliter- 
ation of  the  glandular  structure  with  sometimes  perma- 
nent enlargement,  followed  occasionally  with  atrophy  <rf 
the  glands.  New  growths  are  not  particularly  firequent. 
Tubercle  has  never  been  discovered  in  the  pancreas,  and 
cancer  rarely  attacks  the  gland  primarily.  The  pancreas 
maybe  the  seat  of  an  extensive  accumulation  of  fat  In- 
deed, the  whole  organ  may  be  converted  into  one  mass  of 
fatty  tissue.  Cysts,  cartilaginous  and  osseous  growths  axe 
found  very  rarely.  Cancer  when  found  involving  thc^an- 
creas  is  usually  a  complication  of  extensive  carcinoma- 
tous diseases  of  other  organs.  The  ducts  of  the  pancreas 
may  be  dilated,  or  compressed,  or  completely  obfiterated 
Calcareous  deposits  in  the  excretory  ducts,  giving 
rise  to  obstruction  or  obliteration,  may  be  found,  or  there 
may  be  an  accumulation  of  secretion  and  consequent  di- 
latation. 

Orth  differs  in  some  respects  in  regard  to  the  firequency 
of  tubercle  and  primary  cancer,  but  in  the  main  agrees 
with   the  compilation  given   above.     Ziegler    presents 

>  Orth :  Diagnosis  of  Pathological  Analomy.  p.  333. 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


507 


nothing  of  importance  in  his  recent  work  on  pathologi- 
cal anatomy. 
Having  now  considered  the  physiology  and  pathology 

of  the  organ  we  are  in  a  position  to  study  the  general 

symptoms  of  diseases  of  the  pancreas. 
The  first  symptom  which  I  will  notice  is  emaciation, 

proceeding  to  an  unusual  degree,  and  where  it  cannot  be 

explained  in  the  usual  manner.     We  ought  not  to  forget, 

however,  that  great  loss  of  flesh  is  liable  to  take  place  in 
diseases  of  any  of  the  digestive  apparatus,  and  it  will  be 
only  by  excluding  other  diseases,  and  by  carefully  watch- 
ing the  case,  that  we  shall  be  able  to  gain  any  informa- 
tion from  this  source.  It  is  altogether  probable  that  the 
function  of  the  pancreas  may  be  taken  up  and  very 
largely  compensated  by  the  other  digestive  fluids,  and  we 
do  not  forget  that  experiments  have  been  made  upon  the 
lower  animals,  and  young  dogs  have  recovered  and  lived 
after  extirpation  of  this  organ  ;  but  this  symptom  (emaci- 
ation) associated  with  tenderness  in  the  vicinity  of  the 
pancreas,  and  with  no  apparent  disease  of  other  neigh- 
boring organs,  should  be  taken,  it  appears  to  me,  as  a 
possible  indication  of  disease. 

A  second  symptom,  and  one  which,  it  will  be  remem- 
bered, was  present  in  one  of  my  patients,  is  a  flow  of 
saliva-looking  fluid  from  the  mouth.  This  occurred  to  a 
very  considerable  degree  in  the  case  of  Mr.  R . 

We  are  well  aware  that  in  diseases  of  the  stomach  the 
eructation  or  spitting  of  saliva-looking  fluid  is  a  very 
prominent  symptom,  and  unless  we  take  into  considera- 
tion other  symptoms,  referable  to  the  pancreas,  this  one 
symptom,  it  appears  to  me,  loses  its  diagnostic  value. 

The  presence  of  fat  in  the  stools  is*  another  symptom. 
While  the  passage  of  fat  in  stools  has  been  regarded  as  a 
symptom  of  very  great  value,  it  should  be  remembered 
that  when  a  large  amount  of  fat  is  taken  with  the  food, 
the  ordinary  secretions  of  the  digestive  apparatus  do  not 
appear  to  be  able  to  digest  this  unusual  amount,  and  a 
fatty  stool  in  such  a  case  would  be  of  no  diagnostic  value. 

It  appears  to  me  that  in  the  matter  of  fatty  dejections 
it  could  be  regarded  as  a  diagnostic  symptom  only  where 
we  could  demonstrate  that  a  too  great  amount  of  fat  was 
being  taken ,  and  that  the  other  organs  having  to  do  with 
the  digestion  of  fat  were  in  a  comparatively  healthy  con- 
dition. 

One  of  my  patients  vomited  a  large  amount  of  fatty 
material.  I  do  not  now  remember  of  seeing  this  recorded 
as  taking  place  in  any  other  case  of  disease  of  the  pan- 
creas. 

Among  other  symptoms,  we  should  speak  of  pain  and 
tenderness  in  the  epigastrium ;  but  we  should  also  re- 
member that  a  very  great  variety  of  diseases  of  the  abdom- 
inal organs  in  this  vicinity,  such  as  diseases  of  the  stom- 
ach, liver,  lymphatics,  aorta,  spine,  etc,  are  attended  with 
pain  and  tenderness. 

In  the  consideration  of  individual  symptoms,  which  will 
receive  attention  at  another  place  in  this  paper,  I  shall 
hardly  mention  the  possible  connection  of  pancreas  dis- 
ease with  diabetes  mellitus.  This  complication  does 
occur  in  some  cases,  but  the  explanation  of  the  last- 
named  disease,  as  we  now  understand  it,  would  demand 
a  discussion  relating  to  certain  parts  of  the  nervous  sys- 
tem at  greater  length  than  the  limits  of  this  paper  would 
permit.     Sugar  was  not  present  in  any  of  my  cases. 

Etiology. — Concerning  the  cause  of  pancreas  disease, 
whether  it  be  anaemia  or  hypersemia,  atrophy  or  hyper- 
trophy, acute  or  chronic  pancreatitis,  nothing  is  definitely 
known. 

It  seems,  however,  that  constitutional  syphilis  and  al- 
coholic excesses  have  much  to  do  with  producing  these 
diseases,  and  from  Cases  III.  and  IV.  in  my  enumera- 
tion it  would  seem  that  pregnancy  may  be  an  exciting 
cause.  Other  causes  have  been  assigned,  but  they  are 
mostly  problematical. 

Trousseau  says  that  the  pancreas  undergoes  the  same 
changes  that  the  liver  does  in  chronic  alcoholism,  and 
that  the  pancreas  has  six  times  been  seen  by  the  same 


observer  to  be  affected ;  sometimes  altered  in  the  same 
manner  as  the  salivary  glands,  which  are  described  as 
soft,  yellowish,  and  having  their  epithelium  manifestly 
invaded  by  granulo-adipose  degeneration,  or  shrivelled 
or  atrophied  like  the  liver  of  cirrhosis.  I  have  recently 
had  the  opportunity  of  making  an  autopsy  in  a  case 
where  the  immediate  cause  of  death  was  dilatation  of  the 
aorta  with  valvular  disease,  but  in  a  person  who  had  a 
syphilitic  history;  indeed,  in  1872  and  1873  ^^  was  un- 
der my  immediate  care.  Among  the  organs  involved 
which  we  found  at  the  post-mortem,  in  addition  to  those 
having  to  do  with  the  immediate  cause  of  death,  was  hy- 
perplasia and  enlargement  of  the  spleen,  fatty  infiltration 
of  the  liver,  and  marked  evidence  of  chronic  interstitial 
pancreatitis.  I  mention  this  case  not  because  it  has  any 
particular  connection  with  pancreas  diseases,  but  as  a 
case  where  syphilis  was  known  to  have  existed,  and  where 
there  was  found,  ten  years  after,  evidence  of  chronic  in- 
flammation of  the  pancreas. 

I  desire  now  to  pass  in  review  the  four  or  five  princi- 
pal symptoms  which  have  been  supposed  to  be  always 
present  in  disease  of  the  pancreas,  and  to  examine  into 
other  diseases  where  we  frequently  find  these  same  symp- 
toms, in  order  to  arrive  at  some  definite  conclusion  as  to 
the  worth  of  the  so-called  pathognomonic  indications. 
Such  symptoms  as  emaciation,  the  presence  of  fatty 
stools,  the  profuse  flow  of  saliva,  etc.,  what  are  they 
worth  to  us  in  diagnosticating  a  case  of  pancreatic  dis- 
ease? 

It  must  be  remembered,  at  first,  that  in  all  diseases  of 
the  digestive  apparatus  which  continue  for  any  length  of 
time  there  is  more  or  less  emaciation.  We  find  it,  too,  in 
diseases  of  the  stomach,  and  in  chronic  diseases  of  the 
intestinal  canal.  Particularly  do  we  find  emaciation  in 
cancerous  diseases  of  the  bowels,  where,  in  addition  to 
marked  cachexia  in  almost  all  cases,  we  find  the  loss  of 
flesh  is  very  great ;  there  are,  however,  exceptions  to  this, 
and  persons  have  been  known  to  suffer  from  cancerous 
diseases  of  the  intestines,  verified  by 'an  autopsy,  and 
yet  lose  but  very  little  flesh.  Extreme  emaciation  of  the 
body  usually  takes  place  in  stenosis  of  the  bowels, 
whether  it  be  from  cancerous  disease  or  other  causes. 

In  the  intestinal  parasitic  disease  called  anchylosto- 
mum  duodenale,  a  malady  which  we  know  but  little  of  in 
this  country,  emaciation  is  spoken  of  as  one  of  the  promi- 
nent symptoms.  This  is  a  disease  where  the  parasite 
lives  on  the  blood  which  it  takes  from  the  tissues,  and 
not  only  does  it  abstract  what  it  needs  for  its  own  sus- 
tenance, but  as  it  changes  its  position  it  leaves  wounds 
from  which  there  is  a  constant  escape  of  blood. 

We  have,  then,  here  a  disease  with  all  the  symptoms  of 
chlorosis,  with  its  attendant  paleness  of  the  general  in- 
tegument and  of  the  mucous  membranes,  with  great  fa- 
tigue, dyspepsia,  and  palpitation  of  the  heart,  which  will 
require  great  care  to  differentiate  from  other  diseases 
of  bad  nutrition.  The  parasite  gradually  extracts  blood 
from  the  mucous  membrane  of  the  alimentary  canal,  and 
in  this  way  produces  not  only  all  the  symptoms  ot 
anaemia,  but  the  particular  symptoms  of  emaciation  of 
which  I  am  now  speaking.  The  fact,  however,  that  this 
disease  takes  place  in,  or  is  imported  from,  tropical  cli- 
mates, will  enable  us  to  exclude  it  when  we  are  tr3dng  to 
differentiate  pancreas  diseases. 

Emaciation  is  also  a  symptom  of  a  dilated  stomach, 
a  disease,  by  the  way,  which  it  appears  to  me  takes 
place  with  greater  frequency  than,  perhaps,  the  profes- 
sion recognizes.  In  this  difficulty,  while  the  stomach  is 
very  large,  witli  apparent  obesity,  yet  there  are  all  the 
symptoms  of  poor  nutrition.  The  patient  is  pale,  hollow- 
eyed,  and  is  reduced  nearly  to  a  skeleton.  There  is 
also  with  this  a  real  loss  of  physical  strength. 

We  find  emaciation,  too,  in  cirrhosis  of  the  liver  at- 
tended with  anaemia  and  loss  of  strength.  This  symptom 
in  cirrhosis  appears  frequently  early,  and  long  before 
those  more  prominent  symptoms,  such  as  ascites,  etc., 
which  occur  toward  the  end  of  the  disease.     In  some 


5o8 


THE  MEDICAL  RECORD. 


[November  8,  1884. 


cases  it  is  only  when  nutrition  has  become  disordered 
and  emaciation  and  loss  of  strength  are  noticed  that  the 
patient  first  realizes  that  he  has  some  disease. 

We  find  emaciation  in  splenic  diseases  with  rigors  and 
a  fever,  ofttimes  of  a  hectic  character,  with  sweats, 
oedema,  slight  jaundice  and  diarrhoea,  the  patients  in  the 
meantime  emaciating  rapidly. 

This  is  a  symptom,  too,  that  we  find  present  in  certain 
nervous  diseases,  and  along  with  the  other  symptoms  of  a 
unilateral  progressive  atrophy  of  the  face  we  find  emacia- 
tion taking  place  as  a  symptom.  In  Basedow's  disease  it 
is  a  very  prominent  symptom.  In  a  paper  which  I  pre- 
sented to  the  Illinois  State  Society  some  years  ago,  I 
considered  at  length  the  symptom  and  progress  of  this 
disease,  and  placed  on  record  the  histor)'  of  a  case  where 
the  emaciation  had  taken  place  to  such  a  degree  that  a 
lady  weighing  ordinarily  one  hundred  and  seventy  pounds 
became  reduced  to  probably  ninety.  In  such  a  case, 
however,  there  are  so  many  other  symptoms  present  that 
we  can  at  once  exclude  any  probability  of  pancreas  disease. 

Emaciation  is  present  in  scrofulous  and  tubercular  dis- 
eases, and  proceeds  to  a  very  considerable  extent  with 
the  fever  and  loss  of  appetite  which  we  find  in  chronic 
pleurisy  or  empyema. 

It  is  thus  seen  that  if  we  place  great  stress  upon  the 
one  symptom  of  emaciation  to  help  us  in  making  up  our 
diagnosis  in  pancreas  diseases  we  shall  become  involved 
in  great  perplexity,  for  we  have  already  seen  that  many 
diseases,  and  many  of  them  quite  as  obscure  as  those  of 
the  pancreas,  are  attended  with  constant  and  progressive 
loss  of  fiesh. 

In  regard  to  the  second  symptom — that  of  the  flow  of 
saliva,  or  a  mucous-colored  fluid  from  the  mouth — we  find 
that  this,  too,  is  present  in  a  considerable  number  of  dis- 
eases, although  not  to  the  same  extent  that  we  find  ema- 
ciation. 

The  attempt  that  has  been  made  to  base  a  theory  that 
a  sympathetic  or  vicarious  relationship  exists  between 
the  pancreas  and^ salivary  glands  has  no  good  foundation, 
and  the  increased  secretion  of  saliva  which  is  present  in 
a  very  considerable  number  of  chronic  diseases  of  the 
stomach  has  no  connection  whatever  with  any  function 
of  the  pancreas,  and  in  those  cases  where  a  considerable 
amount  of  saliva  is  vomited  in  the  morning,  in  all  prob- 
ability it  has  been  secreted  and  swallowed  during  the  night 
'  *  It  has  appeared  to  me,  however,  since  I  have  watched 
Cases  III.  and  IV.  of  cirrhosis  of  the  pancreas  in  my 
practice,  that  there  may  be  some  reasons  for  expecting 
that  the  great  abdominal  salivary  gland  (the  pancreas) 
^nay  be  influenced  by  the  same  causes  which  produce 
impressions  on  the  salivary  glands  in  the  mouth.  The 
demonstration  of  this  must  remain  for  future  study. 

In  diseases  of  the  nervous  system  we  find  an  increased 
flow  of  saliva,  but  we  are  usually  able  to  find  some  local 
paralysis  as  the  direct  cause.  In  progressive  bulbar 
paralysis  there  is  sometimes  a  constant  flow  of  saliva 
from  the  mouth,  sometimes  watery  and  sometimes  more 
like  transparent  mucus,  and  yet  progressing  to  such  an 
extent  as  to  be  of  great  annoyance  to  the  patient.  It  is 
frequently  present  m  facial  paralysis  and  in  some  forms 
of  neuralgia. 

Coming  to  consider  the  presence  of  fat  in  the  stools 
and  other  excretory  products  it  seems  that  we  really  have 
in  this  a. symptom  of  more  importance  than  any  hitherto 
mentioned,  but  it  is  not  always  pathological,  as  it  has 
been  observed  in  the  faeces  of  healthy  persons  who  are 
partaking  of  a  greater  amount  of  fat  in  food  than  was 
usual,  and  more  than  can  be  digested  by  the  apparatus 
having  this  to  accomplish. 

It  is  also  found  in  the  stools  of  children  apparently 
healthy,  and  in  some  cases  the  white  lumps  which  we 
suppose  to  be  undigested  casein  are  largely  made  up  of 
fats  ;  the  fatty  acids  combine  with  lime  in  forming  them.* 

It  has  been  seen  in  the  stools  of  patients  suffering  from 

.,    »  Professor  T.  Uflfelmann  :  Arch.  KinderhcUkunde,  x88o. 


slight  jaundice  and  other  evidences  of  a  temporary  disease 
of  the  liver.  There  is  probably  associated  with  this,  at 
least  in  some  cases,  a  partial  occlusion  of  the  pancreatic 
ducts,  and  recovery  will  usually  take  place. 

Fat  is  found  sometimes  in  the  stools  of  persons  afflict- 
ed with  chronic  jaundice,  where  there  is  occlusion  of  the 
ductus  choledochus,  either  alone  or  associated  with 
temporary  closure  of  the  pancreatic  duct  If  a  large 
amount  of  fat  made  its  appearance  it  would  be  an  indica- 
tion that  the  fat  digestive  fimctions  of  both  organs,  liver 
and  pancreas,  were  probably  impaired. 

Fatty  urine  has  been  found  either  alone  or  in  the  same 
patient  where  fatty  stools  have  taken  place.  Several 
cases  of  this  kind  are  on  record,  and  among  the  post- 
mortem revelations  some  disease  of  the  pancreas  has 
been  found. 

In  looking  over  the  literature  for  cases  in  which  fat 
has  been  found  in  the  urine,  I  was  impressed  with  the 
similarity  of  the  symptoms  present  in  pancreas  disease 
with  fatty  urine,  and  the  history  of  cases  described  under 
the  head  of  chylous  urine. 

In  1876  Professor  Hollister  read  a  paper  on  the  sub- 
ject  of  chylous  urine  before  the  Illinois  State  Society,  and 
I  cannot  but  notice  the  analogous  symptoms  as  related 
in  his  paper. 

The  emaciation,  epigastric  pain,  and  loss  of  fat  corre- 
spond to  a  very  considerable  degree  with  those  same 
symptoms  so  frequently  present  in  diseases  of  the  pan- 
creas.' The  theory  was  even  then  advanced  as  to  the 
possibility  of  some  undiscovered  connection  between  the 
lacteal  or  lymphatic  system  and  the  urinary  passages. 
More  recently  the  thought  has  been  advanced  as  to  the 
passage  of  large  amounts  of  fat  from  adipose  tissue  of 
the  body  to  the  blood,  and  thence  through  the  vessels  of 
the  intestinal  mucous  membrane  being  set  free.  The  dis- 
covery of  the  embryo  of  a  round  worm  in  the  blood  of 
those  affected  with  chyluria  has  happily  made  its  pathol- 
ogy certain.  I  wish  I  might  say  as  much  in  regard  to 
diseases  of  the  pancreas. 

The  vomiting  of  fat  is  a  symptom  which  I  do  not  now 
remember  to  have  seen  mentioned  in  any  article  on  dis- 
eases of  the  pancreas  to  which  I  have  had  access.    It 

was  present  in  the  case  of  Mr.  R ,  and  considering  the 

fact  that  the  head  of  the  pancreas  was  considerably  en- 
larged, so  much  so  as  in  all  probability  to  press  against 
the  duodenum,  it  is  not  surprising  that  a  regurgitation 
took  place. 

If  blood  or  bile  may  be  diverted  from  the  intestinal 
canal  and  thrown  back  into  the  stomach  when  pressed 
upon  by  a  cancerous  or  any  other  indurated  mass,  it 
seems  possible  to  me  that  the  fatty  food  which  has  been 
partially  acted  upon  by  the  secretions  of  the  duodenum 
in  the  vicinity  of  the  pancreatic  and  biliary  ducts  may  be 
pressed  back  into  the  stomach  and  vomited  as  fatty 
matter. 

In  conclusion,  I  can  only  say  that  notwithstanding  the 
fact  that  I  have  seen  four  cases  of  cirrhosis  of  the  pan- 
creas, and  have  studied  faithfully  all  the  literature  at  my 
command,  diseases  of  that  organ  will  still  remain  to  me 
diflicult  to  diagnosticate. 

In  my  second  case,  more  from  the  striking  similarity  in 
the  general  appearance  of  the  two  men  than  from  any 
one  particular  symptom,  did  I  venture  to  suggest  pan- 
creas disease.  More  by  excluding  everything  else,  it  ap- 
pears to  me,  must  we  base  our  diagnosis. 

In  my  third  case.  Dr.  Haven  is  kind  enough  to  give 
me  credit  for  speaking  of  disease  of  the  pancreas  as  the 
possible  cause  of  such  a  degree  of  emaciation;  and  in  my 
fourth  case  the  diagnosis  was  made  and  adhered  to,  the 
autopsy  justifying  the  opinion. 

It  is  not  clear  that  fatty  matter  was  passed  from  the 
bowel  in  either  of  my  cases ;  but  it  was  evident  in  both 
that  the  fats  were  not  relished,  were  not  well  assimilated 
if  taken,  and  that  the  system  was  destitute  of  those  fatty 
constituents  upon  which  blood  and  tissue  must  be  re- 
plenished. 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


509 


Notwithstanding  the  fact  that  fat  was  not  passed  in  my 
cases,  after  excluding  those  cases  where  fat  is  normal  or 
accidental,  I  should  certainly  regard  the  presence  of  fat 
in  the  stools  as  one  of  the  most  valuable  symptoms  in 
making  our  diagnosis. 

The  value  of  vomiting  fat  as  a  sign  of  pancreas  disease 
must  be  studied  in  a  greater  number  of  cases.  I  simply 
place  on  record  the  fact  that  it  was  present  in  my  second 
case. 

Emaciation  takes  place  in  so  many  diseases  that  unless 
we  find  the  majority  of  the  other  symptoms  of  pancreas 
disease  present^  it  cannot  be  taken  as  a  sign  of  great  im- 
portance. 

The  extreme  whiteness  of  the  tissues  will  be  regarded 
the  most  prominent  symptom. 

TreattnenL — I  have  nothing  to  add  which  is  new ;  but 
with  the  improvement  which  took  place  in  the  case  in 
which  I  gave  the  pancreatine  but  a  very  imperfect  trial, 
I  certainly  feel  that  the  use  of  this  remedy  should  be  in- 
sisted upon  until  its  value  is  fully  demonstrated — either 
pancreatine  as  we  have  it  in  the  shops,  or  in  emulsion,  or 
what  would  probably  be  better  than  either,  the  freshly 
prepared  calves'  or  pigs'  pancreas. 

These  preparations  should  be  given  some  time  after  each 
meal,  and  without  acids. 

These  remedies  in  the  marasmus  and  infantile  dyspep- 
sias, where  there  exists  an  inability  to  digest  fatty  and 
starchy  foods,  should,  it  appears  to  me,  have  a  more  ex- 
tended trial  than  we  have  hitherto  given  them. 

Conclusions, — First,  from  the  study  of  diseases  of  the 
pancreas  which  I  have  given  up  to  this  time,  it  appears 
to  me  that  inflammations  of  this  organ  are  more  frequent 
than  we  have  hitherto  supposed. 

Secondly,  chronic  inflammation  of  this  gland  is  charac- 
terized by  great  loss  of  flesh,  extreme  whiteness  of  the 
tissues,  and  generally  pain  in  the  region  of  the  affected 
organ.  The  appetite  in  some  cases  continues  excellent, 
and  the  patient  may  take  food  until  the  hour  of  death. 
The  pulse  and  temperature  remain  nearly  normal.  Among 
other  symptoms  which  may  or  may  not  be  present,  is  the 
passage  of  fat  from  the  bowel  or  its  eructation  from  the 
stomach. 

Thirdly,  the  pathological  processes  produce  the  organ 
hardened,  connective  tissue  increased,  glandular  and 
secreting  structure  pressed  upon  or  obliterated. 

Queries. — i.  Are  not  a  considerable  number  of  cases 
commonly  diagnosticated  as  pernicious  anaemia,  leucocy- 
thaemia,  chlorosis,  etc.,  due  to  chronic  inflammation  of  the 
pancreas  ? 

2,  Have  we  here  a  disease  to  which  the  name  **  pan- 
creatic anaemia  "  should  be  given  ? 


Idiopathic  Convulsions  of  the  Tongue. — Dr.  O. 
Berger  relates,  in  the  Neurologisches  CeniralbleUt^  the  case 
of  a  woman,  twenty-eight  years  of  age,  who  was  seized 
suddenly,  without  any  prodromata,  and  in  the  midst  of 
perfect  health,  with  a  peculiar  spasm  of  the  tongue. 
She  experienced  a  sensation  of  tension  in  the  supra- 
laryngeal  region  immediately  beneath  the  chin,  and  then 
the  tongue,  which  seemed  to  the  patient  to  be  enormously 
swollen,  underwent  a  number  of  undulatory  movements. 
At  the  end  of  about  ninety  seconds  the  organ  was  pro- 
jected violently  forward,  striking  the  dental  arch  with  a 
perceptible  noise  or  appearing  between  the  lips.  These 
convulsions  occurred  rhythmically,  succeeding  each  other 
fifty  or  sixty  times  a  minute.  Speech  and  deglutition 
were  impossible  during  the  continuance  of  the  attack, 
which,  however,  caused  no  other  trouble.  The  author 
cites  another  case  of  a  man,  forty-two  years  of  age,  who 
6ad  similar  convulsions,  not  preceded,  however,  by  the 
undulatory  aura.  This  patient  frequently  wounded  his 
tongue  by  closing  involuntarily  his  teeth  upon  it  Dr. 
Berger  referred  these  spasms  to  central  excitation,  cor- 
tical or  bulbar,  of  the  hypoglossus.  A  cure  was  obtained 
by  galvanism  and  hypodermic  injections  of  atropine. 


YELLOW   FEVER  AT    PANAMA— ITS  CAUSE 
AND  TREATMENT. 

By  C.  H.  WILLIAMSON,  M.D., 

p.    »l.    STKAMBS  ACAPULCO. 

Having  had  some  experience  with  yellow  fever  at  diflfer- 
ent  times,  and  most  recently  on  the  Isthmus  of  Panama, 
I  am  induced  to  give  a  few  impressions  formed  in  regard 
to  the  cause  and  treatment  of  that  disease,  though  the 
views  presented  may  prove  neither  novel  nor  interesting 
to  the  profession. 

Yellow  fever  is  unquestionably  a  disease  of  marine 
origin,  and  an  essential  element  in  its  production  is  salt- 
water^ with  the  organic  vegetable  and  animal  matter  con- 
tained therein.  This  is  established  by  the  fact  that  the 
disease  is  never  known  to  originate  away  from  the  sea- 
coast  or  where  salt-water  does  not  permeate.  Ordinary 
malarial  fevers  may  arise  in  any  locality  where  heat, 
moisture,  vegetation,  and  telluric  influences  combine  to 
produce  them,  but  the  specific  fever  under  consideration 
never  can  be  produced  without  the  additional  element 
derived  from  the  sea  or  its  tributaries.  Whether  this 
is  evolved  from  the  decomposition  of  the  vegetable  or 
animal  constituents  of  the  salt-water  b  uncertain,  but  it 
is  probable  that  both  contribute  a  share.  Dr.  Domingo 
Freire,  of  Rio  de  Janeiro,  who  claims  to  have  discovered 
the  germ  of  the  fever  in  the  "  cryptococcus  exogenicus,'' 
says  it  is  of  vegetable  origin,  but  does  not,  I  believe,  as- 
cribe it  necessarily  to  a  marine  source.  I  am  inclined  to 
the  opinion  that  the  animal  matter  of  the  infusoria  in 
sea  water,  by  its  decomposition,  plays  a  more  important 
part  in  the  causation  of  the  disease  than  the  vegetable. 
This  is  shown  by  the  prevalence  of  the  fever  on  board 
vessels  into  whose  holds  sea  water  has  leaked  and  satu- 
rated the  timbers,  and  it  is  probable  that  this  water  in  its 
percolation  has  borne  with  it  more  of  its  animal  than 
vegetable  constituents,  whose  decomposition  in  the  hot 
and  unventilated  apartments,  combined  with  other  favor- 
ing, deleterious  agents,  infects  the  atmosphere  and  gener- 
ates or  maintains  the  disease.  This  is  chiefly  the  case 
with  wooden  vessels,  as  those  built  of  iron  rarely  leak, 
have  no  timbers  to  saturate,  and  can  be  kept  dry  and 
clean  ;  hence  are  always  more  healthy. 

Another  reason  for  the  belief  in  the  marine  animal 
origin  of  the  fever  is,  that  in  all  tropical  regions  where  it 
chiefly  prevails  coral  reefs  abound,  and  animal  marine  life 
is  most  abundant  These  reefs,  when  left  bare  by  the 
tides  and  exposed  to  the  intense  rays  of  a  tropical  sun, 
aflbrd  abundant  material  for  rapid  decomposition,  and 
are  doubtless  most  active  agents  in  polluting  the  air. 

The  town  of  Aspinwall,  on  the  Isthmus  of  Panama,  is 
located  on  a  small  island  almost  surrounded  by  a  coral 
ree£  Here  yellow  fever  is  endemic,  and  sporadic  cases 
occur  at  all  seasons  ;  but  occasionally  it  becomes  epi- 
demic, as  was  notably  the  case  in  the  spring  and  summer 
of  1880.  At  that  time  there  was  an  unusual  prevalence 
of  low  tides  and  the  reef  was  exposed  nearly  aJl  the  time 
to  the  sun,  emitting  an  extremely  disagreeable  odor,  and 
cases  of  yellow  fever  were  more  numerous  in  the  resi- 
dences near  and  fronting  the  beach  than  in  other  locali- 
ties, though  they  occurred  in  other  parts  of  the  town, 
where  coral  rock,  broken  from  the  reef,  was  taken  to  fill 
up  low  places  and  prepare  for  the  foundations  of  build- 
ings. A  stop  was  soon  put  to  this  operation,  but  of  late 
it  has  been  renewed,  and  cases  of  yellow  fever  continue 
to  occur.  Two  vessels  that  took  coral  rock  as  ballast 
had  this  fever  break  out  on  their  voyages.  If  the  germ 
of  this  disease  is  evolved,  as  I  think  it  is,  from  the  polyps 
of  coral  and  other  decomposing  marine  animal  matter,  it 
finds  a  most  congenial  atmosphere  in  which  to  develop 
and  spread  (and  it  only  can  do  so  where  the  conditions 
are  favorable)  at  Aspinwall,  where  heat,  moisture,  and 
filth  of  every  kind  render  it  one  of  the  most  abominable 
places  on  the  globe,  and  where  the  utter  neglect  of  all 
sanitary  measures  causes  wonder  that  human  life  can 
exist  at  all. 


5IO 


THE  MEDICAL  RECORD. 


[November  8,  i884* 


The  germ  of  the  fever,  whatever  it  may  be,  is  readily 
conveyed  by  fomites  in  the  air  from  an  infected  place, 
and  will  rapidly  show  its  effects  wherever  carried,  if  heat 
and  all  other  concomitants  are  supplied,  but  in  a  tem- 
perature below  70°  it  cannot  survive,  and  at  once  disap- 
pears. 

That  the  disease  cannot  be  conveyed  by  personal  con- 
tagion is  too  well  established  a  fact  to  admit  of  doubt, 
and  was  fully  proved  in  the  terrible  epidemic  that  pre- 
vailed at  Norfolk,  Va,,  in  1855. 

In  regard  to  the  treatment  of  the  fever,  as  the  kidneys 
play  the  most  important  part  in  its  pathology,  special  at- 
tention should  be  paid  to  their  function  and  every  effort 
made  to  keep  up  their  secretion  as  indispensably  neces- 
sary to  a  cure.  Suppression  of  urine  is  the  worst  symp- 
tom, and,  however  grave  all  the  others  may  be,  if  that 
one  is  absent,  there  is  hope  of  recovery.  I  have  seen 
patients  get  well  after  having  "  black  vomit,"  and  all  the 
other  most  unfavorable  symptoms  except  suppression^ 
and  until  that  sets  in  ^he  prognosis  is  favorable ;  but  after 
it  appears  and  continues  for  over  twenty-four  or  thirty 
hours  the  case  may  be  regarded  as  hopeless.  In  those 
attacks  where  from  the  onset  the  brain  bears  the  onus  of 
the  disease  and  maniacal  delirium  appears  early,  soon 
subsiding  into  profound  coma,  death  generally  speedily 
ensues  ;  but  with  the  exception  of  these  brain  and  kid- 
ney complications,  and  their  proportion  is  not  very  large, 
the  fever  usually  yields  to  prompt  and  proper  treatment. 
This  should  be  commenced  at  once  with  hot  mustard 
baths  of  the  lower  extremities,  and  the  administration  of 
a  brisk  cathartic  ;  the  patient  then  put  to  bed  and  cov- 
ered with  blankets ;  given  drinks  to  promote  diaphoresis, 
and  sinapisms  applied  over  the  epigastrium  and  region 
of  the  kidneys.  If  after  free  perspiration  and  puigation 
the  fever  does  not  subside,  a  tentative  dose  of  fifteen  or 
twenty  grains  of  quinine  may  be  given,  but  should  not 
be  repeated  if  it  fail  to  reduce  the  temperature  or  in- 
creases the  headache.  Should  it  act  otherwise  it  may 
serve  to  abort  the  disease,  and  can  be  repeated  in  a 
smaller  dose  in  three  or  four  hours.  The  fever  persist- 
ing, the  use  of  diuretics  and  refrigerant  diaphoretics 
should  be  vigorously  employed,  particularly  the  former, 
to  promote  the  urinary  secretion.  A  combination  of  po- 
tass, nitrat.,  grs.  x.  ;  spts.  nit.  dulc,  3  j. ;  tinct  aconit. 
rad.,  gtt.  j.  ;  aquae,  3  ss.,  every  second  hour,  I  have 
used  with  advantage,  and  found  it  generally  retained  by 
the  stomach.  The  acetate  or  chlorate  of  potass,  may  be 
substituted  for  the  nitrate  in  this  prescription  ;  or  the  lat- 
ter m3Ly  be  given  with  sulphur,  sublim.  and  pulv.  carbo- 
nis  (one  as  a  germicide,  the  other  as  an  antiseptic),  with 
good  effect.  The  action  of  the  kidneys  may  also  be  pro- 
moted by  the  bitart.  potass,  as  a  drink,  and  the  applica- 
tion of  dry  cups,  turpentine  stupes,  and  fomentations  to 
the  loins.  When  gastric  irritability  sets  in,  the  stomach 
should  be  kept  as  quiet  as  possible  and  nothing  given  as 
long  as  it  is  quiet ;  but  if  it  will  not  remain  so,  of  all  the 
remedies  I  have  found  nothing  better  than  milk  and 
lime-water  to  allay  the  nausea  and  vomiting.  When 
"  black  vomit  "  occurs  I  have  arrested  it  with  ergot  and 
tinct.  ferri  chid. 

Having  thus  outlined  the  general  system  of  treatment 
I  have  found  most  beneficial,  regard  for  your  valuable 
space  warns  me  not  to  go  more  into  detail  of  the  variety 
of  remedies  employed  to  meet  the  different  indications 
in  the  stages  of  remission  and  collapse. 

The  temperature  of  the  apartment  of  the  patient 
should  be  kept  as  uniform  as  possible,  and  during  the 
entire  period  of  the  attack  he  should  be  kept  moderately 
covered  by  bed-clothing  and  never  subjected  to  a  sudden 
change.  His  diet  should  consist  of  milk,  gruel,  and 
animal  broths,  given  in  very  small  quantities  at  a  time 
and  frequently  repeated,  and  stimulants  employed  when 
indicated  after  the  subsidence  of  fever.  A  return  to 
solid  food  during  convalescence  should  be  very  gradual, 
and  great  caution  in  this  matter  is  imperatively  de- 
manded. 


THE   COCA   LEAF  AND   ITS  ALKALOID. 
By  WILLIAM  OLIVER  MOORE,  M.D., 

PROFESSOR    OF     BVH   AND   BAR    DISEASES,     NEW    YORK    POST-GRADUATE   MEDICAL 
SCHOOL  AND  HOSPITAL. 

The  importance  which  has  been  attached  to  the  alkaloid 
of  the  coca  leaf  during  the  past  few  days  in  ophthalmic 
surgery  has  led  me  to  bring  together  a  few  facts,  historic 
and  otherwise,  for  the  general  reader,  knowing  that 
doubtless  they  would  prove  of  interest. 

Cuca,  or  coca  (erythroxylon  coca),  as  called  by 
the  natives  (erythroxylum  peruvianum),  is  found  wild  in 
the  mountains  of  Peru  and  Bolivia,  and  is  also  cultivated 
on  high  altitudes.  The  leaf  is  the  part  of  the  plant  in 
which  the  active  principle  resides.  These  leaves,  which  re- 
semble those  of  the  tea-plant,  are  gathered  from  plants 
varying  in  age  from  one  to  upward  of  forty  years.  They 
are  considered  ready  for  plucking  when  they  break  on 
being  bent,  and  are  gathered  in  March  (after  the  rainy 
season,  this  being  the  most  abundant  crop),  in  July,  and 
in  November.  Good  samples  of  the  dried  leaves  are  un- 
curled, with  a  deep  green  upper  and  a  gray-green  lower 
surface,and  have  a  strong,  tea-like  odor.  Bad  specimens 
have  a  brown  color  and  a  smell  resembling  camphor 
The  flowers  of  the  plant  are  small  and  white,  and  are 
succeeded  by  red  berries. 

The  seeds  are  sown  in  December  and  January;  the 
cultivation  of  the  plant  gives  employment  to  thousands 
of  the  people,  and  the  annual  production  in  Bolivia  and 
Peru  in  1864  was  estimated  at  two  million  five  hundred 
thousand  dollars  in  value. 

The  green  leavrs  are  spread  on  coarse  woollen  cloths 
and  dried  in  the  sun,  then  packed  in  bags,  which,  in 
order  to  preserve  the  efficacy  of  the  leaves,  must  be  kept 
free  from  dampness.  The  leaves  are  worth  in  Peru 
seventy-five  cents  a  pound,  and  cost  here  one  dollar. 

The  habit  of  the  natives  of  the  western  countries  of 
South  America  to  chew  the  coca  leaf,  has  given  much  in- 
terest to  this  plant ;  the  dried  leaves  are  chewed  mixed 
with  quicklime,  which  is  said  to  make  its  flavor  more 
sensible  to  the  taste.  In  the  same  way  the  leaf  of  the 
betel-nut  is  used  by  the  East  Indians. 

The  leaves  are  called  cuca  by  the  Indians,  and  coca  by 
the  Spaniards.  It  has  been  estimated  that  cuca  or  coca 
is  used  by  eight  millions  of  the  human  race,  consuming 
thirty  millions  of  pounds  per  annum,  by  chewing  the 
leaves  made  into  a  ball  mixed  with  lime.  The  leaves 
are  deprived  of  their  stalks,  two  or  three  ounces  of  them 
being  used  during  one  day.  It  is  a  powerful  stimulant 
to  the  nervous  system,  enabling  fatigue  to  be  borne  with 
less  nourishment  and  greater  ease  than  usual.  A  case  is 
reported  by  Whittingham,*  in  1850,  of  two  men  being 
buried  in  a  mine  eleven  days  before  they  could  be  dug 
out,  during  which  time  they  were  kept  alive  by  the  small 
amount  of  coca  they  had  with  them. 

So  much  vaunted  is  the  coca  as  a  stimulant  to  ner- 
vous energy,  that  the  poet  Cowley"  represents  an  Indian 
chief  as  addressing  Venus,  thus  : 

••  Our  Varicocha  first  this  Coca  sent, 
Endow'd  with  Leaves  of  wondrous  Nourishment, 
Whose  Juice  succ'd  in,  and  to  the  Stomach  ta'en 
I^ng  Hunger  and  long  Labor  can  sustain ; 
From  which  our  faint  and  weary  Bodies  find 
More  Succor,  more  they  chear'the  drooping  Mind, 
Than  can  your  Bacchus  and  your  Ccrfs  join'd. 
The  Quitolta  with  this  provision  stor'd 
Can  pass  the  vast  and  cloudy  Andes  o'er." 

It  was  used  by  the  Indians  of  Peru  in  ancient  times,  be- 
ing employed  as  an  offering  to  the  sun ;  it  was  also 
thought  that  unless  the  priest  chewed  these  leaves  during 
his  ceremonies  the  gods  would  not  be  propitiated.  It  is 
still  held  in  veneration,  and  is  thought  by  the  miners  to 
have  an  effect  in  softening  veins  of  ore  if  chewed  and 
thrown  upon  them.  As  to  the  eflfect  of  this  habit  of 
chewing  the  leaves  on  the  system,  much  difference  of 
opinion  exists  ;  on  the  whole  the  opinion  of  Dr.  Smith  * 


1  Thompson's  Cyclopaedia  of  Chemistry.        »  Cowley's  Works,  London,  ijfo- 
*  Peru  as  It  is.     London,  1839. 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


511 


is  in  accordance  with  most  of  the  facts.  He  says  :  "  When 
used  in  moderate  quantity  it  increases  nervous  energy, 
enlivens  the  spirits,  and  enables  the  Indian  to  bear  cold, 
wet,  great  bodily  exertion,  and  want  of  food  to  a  surpris- 
ing degree  with  apparent  ease  and  impunity."  Sir  Robert 
Chiistison,  in  a  paper  read  before  the  Edinburgh  Botanical 
Society,  April  13, 1876,  on  this  subject,  narrates  some  ex- 
periments on  his  students  and  himself,  showing  the  harm- 
lessness  of  the  drug. 

Bouchardat*  states  that  coca  has  rendered  to  thera- 
peutics value  almost  equal  to  the  cinchona  bark,  class- 
ing it  as  a  stimulant  to  the  nervous  and  muscular  sys- 
tems^ and  ranks  it  as  such  with  tea  and  coffee.  He  terms 
it  also  a  "  substance  d'^pargne,"  or  that  which  prevents 
the  rapid  waste  of  tissue.  The  leaf  was  first  introduced 
into  France  by  Joseph  Bain,  a  "  pharmacien,"  about 
186^  from  which  he  made  an  elixir  and  wine.  Vin  Ma- 
riani,  of  recent  introduction  into  this  country,  is  made 
from  these  leaves  ;  we  have  also  a  fluid  extract,  etc. 

Cocaine,  the  alkaloid,  was  discovered  by  Niemann  in 
1855 ;  its  chemical  formula  is  C„H^jNO^ ;  its  physiological 
action  is  apparently  identical  with  that  of  theine,  caf- 
feine, guaranine,  and  theobromine.  Dr.  Alex.  Bennett* 
was  perhaps  the  first  to  conduct  a  series  of  experiments 
with  this  alkaloid,  his  observations  being  made  on  the 
lower  animals,  and  he  concludes  from  these  that :  i. 
Cocaine  is  a  powerful  poison,  inducing  a  series  of  symp- 
toms aflfecting  the  nervous,  respiratory,  circulatory,  and 
vaso-motor  systems,  which  terminate,  if  the  dose  be  large 
enough,  in  death.  2.  In  small  doses,  cerebral  excite- 
ment not  followed  by  coma,  and  partial  loss  of  sensi- 
bility. 3.  In  large  doses  it  produces  cerebral  excite- 
ment, complete  paralysis  of  sensibility,  tetanic  spasms, 
and  death.  4.  It  paralyzes  the  entire  posterior  column 
of  the  spinal  cord,  also  the  entire  system  of  peripheral 
sensory  nerves;  but  the  anterior  columns  of  the  cord 
and  the  peripheral  motor  nerves  are  not  paralyzed.  5. 
It  does  not  produce  muscular  paralysis.  6.  It  usually 
produces  contraction  of  the  pupils.  7.  It  produces  an 
increase  in  the  salivaiy  secretion. 

These  conclusions  were  arrived  at  after  experiments 
conducted  on  more  than  one  hundred  animals  of  differ- 
ent kinds.  Dr.  Ott,  in  The  Medical  Record,  1876, 
finds  similar  physiological  effects,  except  that  he  noticed 
the  pupil  to  dilate;  this  is  in  accordance  with  our  present 
experience.  It  is  interesting  to  note  that  the  neutral 
principles  contained  in  coffee,  tea,  and  chocolate,  bever- 
ages so  generally  in  use,  are  almost  identical  in  chem- 
ical composition,  and  similar  in  physiological  action,  to 
cocaine ;  and  this  fact  may  lead  us  to  find  in  either  theine, 
caffeine,  or  theobromine  local  anaesthetic  properties 
similar  to  the  alkaloid  of  the  coca  plant ;  if  so,  it  would 
be  much  cheaper  and  more  readily  obtained.  Cocaine 
is  a  very  deliquescent  substance  and  it  is  hard  to  obtain 
crystals,  yet  by  patience  they  may  be. 

The  experiments  with  the  cocaine  hydrochlorate,  by 
applying  it  to  mucous  surfaces,  as  the  conjunctiva,  has 
been  known  of  only  about  one  month,  and,  as  far  as  I 
know,  the  American  surgeons  have  been  among  the  first 
to  operate  with  its  use.  The  first  reports  of  these  cases 
are  in  this  journal  (page  438).  Since  then  many  more 
have  been  made,  with  almost  universal  success. 

In  addition  to  the  three  cases  reported  by  me  in  a 
former  number,  I  may  cite  the  following  that  are  of  in- 
terest : 

Case  I. — Ella  M ,  aged  twelve,  leucoma  adhaerens, 

with  partial  closure  of  pupil.  Operation  of  iridectomy 
(artificial  pupil)  performed  under  cocaine.  A  two 
per  cent,  aqueous  solution  was  used  of  the  hydro-chlo- 
rate, dropped  into  the  eye,  eight  drops  during  twelve 
minutes.  At  the  end  of  six  minutes,  four  drops  having 
been  used,  the  conjunctiva  and  nasal  part  of  the  cornea 
were  insensible  ;  in  ten,  the  whole  cornea  was  anaesthetic ; 
two  minutes   later   the   operation  began,  when   it  was 

J  American  Journal  of  the  Medical  Sciences,  vol.  Ixxii. 
*  British  Medical  Journal,  April  x8,  1874, 


noticed  that  the  edge  of  the  pupil  could  be  seen,  showing 
the  mydriatic  effect  of  the  drug.  The  introduction  of 
the  speculum  and  section  of  the  cornea  were  absolutely 
painless.  Fearing  that  the  iris  might  be  sensitive  (as  I 
had  seen  in  another  case),  I  injected  two  drops  of  the 
solution  through  the  corneal  wound  on  to  the  iris  sur- 
face, when  to  my  delight  the  iris  section  proved  to  be 
painless.  The  operatioi*  did  well,  and  was  performed 
on  October  1 7th.  The  patient  was  seen  to-day,  with  no 
irritation. 

Case     II. — Mary    H ,    aged   eleven  ;    leucoma, 

with  anterior  synechia.  Iridectomy  done  at  my  clinic 
at  the  Post-Graduate  Medical  School,  October  17th. 
The  solution  of  four  per  cent,  strength  was  used.  In 
three  minutes  after  the  first  two  drops  were  instilled  the 
conjunctiva  and  cornea  were  almost  anaesthetic.  To 
insure  success  two  more  drops  were  used,  and  at  the  end 
of  seven  minutes  the  operation  was  begun.  The  intro- 
duction of  the  speculum  and  section  of  cornea  were  not 
felt,  but  when  the  iris  forceps  was  introduced  and  the 
iris  cut  the  patient  showed  some  evidence  of  pain.  It 
was  this  that  led  me  to  use  the  cocaine  solution  directly 
to  the  iris  tissue,  as  in  the  case  previously  mentioned. 
This  patient  has  thus  far  done  as  well  as  customary. 

Case  III. — One  of  lachrymal  stricture  ;  James  F , 

aged  twenty-eight.  This  being  the  first  case  where  the  skin 
played  a  part  in  the  operation,  the  experiment  was  con- 
sidered by  me  doubtful.  However,  the  four  per  cent,  solu- 
tion was  freely  applied  above  the  inner  canthus  and  over 
the  openings  to  the  tear  passages,  and  in  six  minutes  the 
parts  were  sufficiently  numb  to  allow  of  the  slitting  of 
the  canaliculus  without  pain.  An  AnePs  syringe,  charged 
with  eight  drops  of  the  cocaine  solution,  was  introduced 
into  the  cut  canal,  and  the  ffuid  forced  into  the  nasal  duct 
as  far  as  it  would  go.  After  waiting  four  minutes  the 
No.  8  probe  was  passed  without  pain  down  to  the  roof  of 
the  mouth  ;  this  was  then  removed  and  a  lead  wire  in- 
troduced, the  patient  all  the  time  having  no  sensation. 
In  twenty  minutes  after  the  injection  the  lead  wire,  which 
was  purposely  left,  was  felt  for  the  first  time. 


Case    IV.— Michael   R- 


aged  thirty-six ;  oritis 
syphilitica.  Complaining  of  much  pain ;  not  relieved 
by  atropine  ;  was  treated  by  instillation  of  cocaine,  two 
per  cent,  solution,  with  relief  of  pain  in  twenty  minutes 
after  its  first  use.  The  drops  were  used,  two  every 
three  minutes  till  eight  had  been  applied.  At  the  end  of 
half  an  hour  the  pupil  was  noticed  to  be  larger  than 
when  the  experiment  was  begun.  Pain  returned  that 
night,  but  not  so  severe  as  before. 

Case  V. — Mamie  B ,  aged  sixteen,  West  Harley, 

N.Y.;  operation  at  New  York  Eye  and  Ear  Infirmary. 
Diagnosis,  irritable  stump.  Thinking  that  the  anaesthetic 
effect  of  cocaine  might  go  deeper  by  a  freer  use,  I  used 
in  this  case  some  twenty  drops,  with  some  benumbing 
influence,  yet  not  sufficient  to  warrant  an  operation  for 
removal  of  the  eye,  so  after  waiting  twenty  rninutes  I 
removed  the  eyeball  in  the  "old-fashioned"  way. 

Case  VI. — The  following  experiments  were  made 
upon  my  own  eye :  October  i6th,  at  the  Academy  of 
Medicine,  Dr.  Agnew  put  in  two  drops  of  a  two  per  cent, 
solution  (Merk's^  in  my  left  eye,  and  in  ten  minutes  the 
conjunctiva  was  insensible.  Not  only  that,  but  in  twenty- 
five  minutes  the  pupil  was  dilated,  and  remained  so  for 
twelve  hours;  the  accommodation  was  also  affected. 
This  took  place  in  thirty-five  minutes  after  the  use  of  the 
drug,  Jaeger  No.  i  being  seen  at  thirteen  inches  only, 
when  with  the  unaffected  eye  my  near  point  was  five 
inches.    In  the  morning  the  accommodation  was  restored. 

October  i8th  a  two  per  cent,  solution  of  cocaine,  ex- 
tracted from  the  leaves  by  Foucar  &  Co.,  New  York,  was 
used  ;  hitherto  all  the  experiments  were  made  with  Merk's 
preparation.  Four  drops  of  this  solution  were  by  Dr. 
Minor  placed  in  my  left  eye,  it  being  in  a  normal  condition, 
during  five  minutes.  At  the  end  of  eight  minutes  the 
conjunctiva  was  held  by  fixation  forceps  and  without  my 
knowledge.     The  anaesthesia  lasted  twenty-two  minutes ; 


512 


THE   MEDICAL  RECORD. 


[November  8,  1884. 


in  twenty-five  minutes  from  the  first  drop  the  pupil  was 
dilated  three-fourths  its  size,  and  the  accommodation 
interfered  with.  This  lasted  six  hours,  the  pupil  remain- 
ing dilated  ten  hours. 

Case  VI I. — M.  B ,  thirteen  years  of  age;  strabis^ 

mus  convergens.  Finding  in  some  operations  for  squint 
that  the  cocaine  acted  on  the  conjunctiva  well,  but  that 
when  the  muscle  was  hooked  pain  was  experienced,  it 
occurred  to  me  well  to  inject  under  the  conjunctiva,  over 
the  site  of  the  muscle  to  be  cut,  a  few  drops  of  the  anaes- 
thetic fluid ;  this  was  done  in  this  case,  six  drops  being 
injected,  and  the  usual  six  to  eight  drops  being  used  on 
the  surface  of  the  eye.  This  procedure  caused  the  pain 
to  be  entirely  abolished.     No  bad  after-effect  occurred. 

This  mydriatic  effect  of  cocaine  is  well  marked  and 
will  make  it  a  valuable  contribution  to  our  list,  as 
ophthalmoscopic  examinations  can  be  made,  and  the  in- 
convenience of  atropine  not  be  felt,  the  effect  on  the  ac- 
commodation in  the  former  being  of  such  short  duration. 
The  chemical  formula  of  atropia  is  almost  identical  with 
cocaine.  The  mydriatic  effect  of  the  cocaine  applied  to 
the  eye  in  man  differs  from  the  effect  noticed  by  Dr. 
Bennett  in  his  experiments,  where  the  drug  was  given 
by  the  stomach  in  animals,  he  finding  a  contracted  pupil 
the  rule.  As  to  the  action  of  the  drug  in  producing 
anaesthesia  of  the  surface  both  of  mucous  membranes  and 
the  skin,  that  is  a  point  still  to  be  worked  out.  Having 
already  trespassed  too  long  on  your  time,  I  will  reserve 
further  experiments  with  this  drug  for  the  future. 

OCTOBBR  18,  1884. 


THE  THERAPKUTIC  VALUE  OF  A  SEA  VOY- 
AGE  IN  CERTAIN  CASES  OF  CHRONIC 
DIARRHOEA. 

By  J.  W.  STICKLER,  M.S.,  M.D., 

ORAMGB,   N.  J. 

While  crossing  the  Atlantic,  I  have  had  opportunity  to 
observe  that  almost  every  voyager  has,  during  the  entire 
trip,  been  more  or  less  troubled  with  constipation.  This 
condition  has  been  referred  to  by  others,  among  whom 
I  mention  C.  Pit  field  Mitchell,  M.R.C.S.,  who  states  in 
his  monograph  on  the  **  Pathology  and  Philosophy  of 
Sea-sickness,"  that  of  twenty-nine  recorded  cases — a 
fraction  only  of  the  number  actually  observed — constipa- 
tion was  present  in  twenty-eight ;  in  the  remaining  one 
early  diarrhoea  and  subsequent  constipation. 

Indeed  this  condition  is  so  common  that  almost  every 
one  anticipating  a  sea  voyage  provides  himself  with  a 
suitable  cathartic.  The  ship's  surgeon  told  me  that  the 
most  common  complaint  of  all  the  passengers,  steerage 
and  cabin,  is  constipation,  and  oftentimes  it  is  of  a  very 
persistent  character,  not  being  relieved  by  salines,  but 
requiring  drugs  more  active.  So  far  as  my  observation 
goes,  it  is  most  obstinate  in  those  who  suffer  longest  from 
nausea  and  vomiting. 

Constipation  in  some  instances  may  be  due  to  the 
presence  of  the  hydrated  peroxide  of  iron  in  the  water 
used  for  drinking  and  cooking.  The  presence  of  the  iron 
is  due  to  the  fact  .that  the  water  is  carried  in  iron  tanks, 
in  which  there  is  quite  a  thick  deposit  of  iron  rust  which 
is  mixed  with  the  water  by  the  constant  motion  of  the 
ship. 

In  many  cases,  however,  there  is  but  little  water  used 
till  after  constipation  is  well  established.  Some  form  of 
alcoholic  stimulant,  or  one  of  the  natural  alkaline  waters, 
is  used  to  assuage  thirst,  and  crackers,  toasted  bread, 
with  perhaps  gruel  and  assorted  fruits,  to  satisfy  hun- 
ger. 

After  the  sea-fickness  and  prostration  accompanying 
it  have  passed  away,  both  water  and  solid  food  are  par- 
taken of  more  freely,  and  the  iron  therein  contained  may 
act  as  an  astringent  upon  the  gastro-intestinal  apparatus. 
H.  M.  Bracken,  M.D.,  L.R.C.S.,  who  has  spent  much  of 
his  time  on  the  Atlantic  Ocean,  writes  me  as  follows  : 


Sailors  would  ask  for  **  black  draught,"  the  formula  for 
which  is  (according  to  the  Brit.  Pharm.) : 

]$.  Infus.  sennae 14    parts. 

Magnesiae  sulph 4       " 

Ext.  glycyrrhizse i  part. 

Tinct.  sennae 2^  parts. 

Tinct.  cardamom,  co i\  part. 

M.  Dose  I  j.  to  5  ss. 

(The  fact  that  they  asked  for  a  cathartic  of  their  own 
accord  indicated  that  they  must  have  been  troubled 
with  constipation,  which  a  comparatively  few  hours  at 
sea  had  produced.)  Passengers  were  generally  served 
with  piL  colocynth  co.  (Brit.  Pharm.)  (Dr.  Gregory's 
favorite  pill),  or  pil.  colocynth  co.  et  hyoscyami  (Dr. 
Christison's  favorite  pill). 

The  percentage  of  passengers  and  crew  affected  at 
the  beginning  of  the  voyage  was  usually  large.  The  con- 
dition would  last  some  time  and  be  quite  troublesome  if 
no  laxative  were  taken.  One  dose  generally  gave  relief, 
and  was  often  sufficient  for  a  voyage  of  such  duration  as 
between  England  and  New  York,  Persons  from  the 
tropics  suffering  from  diarrhoea  were  generally  benefited 
by  a  sea  voyage. 

The  fresh,  pure  air  from  the  sea,  change  of  diet,  change 
of  habit,  etc.,  brought  about  the  improvement 

Very  few  cases  of  diarrhoea  originated  on  board.  These 
were  usually  the  sequelae  of  other  diseases,  or  the  result 
of  gluttony.  When  from  the  latter  cause,  a  good  purga- 
tive and  twenty-four  hours  of  strict  diet  would  relieve. 

I  have  known  others,  who  on  land  had  tried  various 
kinds  of  medication  for  the  relief  of  diarrhoea,  but  without 
success,  not  being  able  to  remove  the  malady  till  they 
went  to  sea. 

Such  patients,  after  being  forty-eight  hours  on  the 
water,  either  had  one  small  alvine  discharge  daily,  or 
every  other  day.  This  condition  remained  till  a  laxative 
or  cathartic  was  taken. 

Great  benefit  was  derived  when  nervousness  was  asso- 
ciated with  the  intestinal  trouble,  especially  that  form 
of  nervousness  which  is  the  result  of  over-mental  work. 

Reynolds  says  :  "  Patients  near  the  coast  should  get 
to  sea.  When  undertaking  a  voyage  care  should  be  taken 
that  suitable  provision  and  nursing  should  be  provided ; 
but  this,  though  possible  for  people  in  good  circumstances, 
is  often  impossible  for  poorer  persons.  There  can  be 
little  doubt  that  being  sent  to  sea  without  comforts  in  an 
advanced  stage  of  the  disease  is  an  aggravation  of  their 
condition,  and  that  they  should  be  spared  this  by  judi- 
cious early  travel.  It  is  to  be  hoped  that  the  time  will 
come  when  all  ocean  passenger  steamers  will  specially 
provide  for  the  comfort  and  care  of  sick  passengers. 
Cabins  with  extra  attendance,  and  good  sick  cookery, 
would  be  a  great  boon  for  the  helpless  invalid  from  diar- 
rhoea and  dysentery." 

In  addition  to  the  class  of  patients  referred  to  by 
Reynolds,  /.^.,  those  reduced  to  a  state  of  extreme  ex- 
haustion, there  are  patients  of  ample  means  who  are  ren- 
dered unfit  for  the  daily  round  of  active  business  life  by 
a  troublesome  diarrhoea,  which  does  not  readily  yield  to 
drugs,  but  which  in  most  instances  would  be  greatly 
benefited  or  cured  by  an  ocean  voyage. 


Copper  as  a  Prophylactic  in  Cholera. — The  P'tit 
Moniteur  de  la  M^decine  recently  issued  an  extra  ednion 
which  was  devoted  entirely  to  a  consideration  of  cholera. 
Among  many  anecdotes  there  appears  the  following: 
One  day  during  the  height  of  the  cholera  scare  in  Pans, 
a  blind  man  was  playing  the  Marseillaise  on  an  old 
trombone  in  a  courtyard.  Joseph  Prudhomme,  who  was 
afraid  of  the  disease,  called  to  him  from  his  window  to 
desist  in  the  name  of  public  health  from  playing  that 
contaminating  hymn.  "My  dear,"  interposed  his  wife, 
"  did  you  not  notice  that  the  instrument  is  copper  ?  " 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


513 


THE  INDUCTION  COII.— ITS  VARIETIES  AND 
THE  DIFFERENTIAL  INDICATIONS  FOR 
THEIR  USE.* 

By  a.  D.  ROCKWELL,  A.M.,  M.D., 

NEW  YOKK. 

When  solicited  to  contribute  something  to  the  annual 
meeting  of  this  Academy  along  that  line  of  research  in 
which  I  have  been  interested  for  so  long  a  time,  I  hesi- 
tated in  the  selection  of  a  topic.  Of  material  there  is 
plenty,  and  of  sufficient  importance.  The  whole  field  of 
the  physics,  physiology,  and  therapeutics  of  electricity 
lies  open  before  us.  The  comparative  value  of  its  three 
subdivisions  offers  a  subject  for  discussion  and  the  rela- 
tion of  experiences,  while  the  differential  indications  for 
the  use  of  these  various  forms — galvanism,  faradism, 
and  franklinism — is  of  still  greater  importance  and  even 
less  understood. 

Vital  in  interest  as  are  each  and  all  of  these  themes, 
and  others  that  occurred  to  my  mind,  they  seemed  to  be 
excluded  from  discussion  here,  since  it  has  been  suggested 
that  whatever  is  presented  should  flavor  somewhat  of 
originality,  or  at  least  be  not  altogether  hackneyed  ;  and 
these  topics  have,  one  and  all,  been  discussed  at  various 
times  in  the  current  medical  literature  of  the  day,  and 
are  more  or  less  fully  considered  in  many  of  the  works 
devoted  to  electro- therapeutics.  The  laudable  aspira- 
tion of  this  Academy,  then,  as  attested  by  the  prospectus 
lately  issued,  confirms  the  aphorism  that  "  originality  is  a 
thing  we  constantly  clamor  for,"  as  well  as  "  constantly 
quarrel  with."  Unfortunately,  however,  pure  originality 
in  thought  or  methods  of  expression  is  the  gift  of  but  few. 
Old  and  long-forgotten  ideas  are  being  constantly  reha- 
bilitated and  brought  forward  under  the  guise  of  new  and 
advanced  opinions.  In  this  way,  much  that  would  other- 
wise be  lost  or  fall  short  of  its  proper  utilization  be- 
comes, through  a  more  persistent  and  perhaps  clearer 
presentation,  a  practical  part  of  the  world's  integral  store 
of  knowledge.  While,  therefore,  none  of  the  facts  in 
physics  that  I  propose  here  to  present  are  in  any  sense 
new,  yet  there  has  been  no  general  appreciation  of  them, 
and  but  little  knowledge,  even  among  those  who  have 
been  endeavoring  in  a  blind  sort  of  way  to  utilize  them, 
that  such  facts  existed. 

As  to  the  few  statements  that  are  made  along  the  line 
of  therapeutics,  the  most  that  I  can  say  of  them  is  that 
they  are  the  result  of  much  experience  and  of  very  many 
carefully  recorded  observations,  and  if  presented  with 
any  measure  of  clearness  ought  to  be  of  some  little 
service  to  those  who  are  interested  in  but  who  have 
given  little  thought  to  the  matter.  But  to  my  theme. 
There  are  two  kinds  of  electro-magnetic  machines  that 
are  presented  to  the  medical  man  for  therapeutical  pur- 
poses. The  first  is  termed  a  separate  coil,  and  the 
second  a  continuous  or  single  coil  apparatus.  The  sepa- 
ratejcoil  apparatus  is  the  one  most  commonly  used  and 
the  one  most  generally  understood.  The  separate  coil 
is  the  variety  described  and  illustrated  in  every  text-book 
of  physics,  but  not  in  sufficient  detail  to  make  clear  its 
mechanism  when  used  for  medical  purposes.  Craving 
the  indulgence  of  those  who  may  be  thoroughly  informed 
on  these  points,  and  who  may  therefore  regard  as  primi- 
tive the  remarks  that  follow,  let  me  by  the  aid  of  the 
accompanying  diagram  (Fig.  i)  describe  the  course  and 
influence  of  the  electric  current  in  an  ordinary  separate 
coil  faradic  apparatus. 

All  induction  machines  are  composed  of  not  less  than 
two  coils.  The  first  or  primary  coil  consists  of  a  large, 
well-insulated  wire  surrounding  a  bundle  of  soft  iron 
wire,  which  forms  a  magnetic  centre.  Over  this  first  or 
primary  coil  is  wound  a  coil  composed  of  several  con- 
volutions of  fine,  well-insulated  wire  for  the  induced  cur- 
rent The  terminals  of  the  first  or  primary  coils  of  wire 
are  united,  one  end  to  the  battery  that  operates  the  coil, 

'  Read  before  the  annual  meeting  of  the  American  Academy  of  ji  Medicine,  at 
Baltimore^  OctotMr  aS,  1884.' • 


and  the  other  to  the  part  of  the  automatic  rheotomefac- 
cording  to  the  following  description.  As  the  battery  is 
the  important  factor,  let  us  start  from  it  and  follow  'the 
connections  and  action  of  the  combinations'lhat  produce 
the  effect : 

The  positive  pole  (P)  of  the  battery  is  connected \with 
the  governor  marked  A  (Fig.  i).  The  negative  pole 
N  of  the  battery  is  connected  with  the  first  end  of  the 
primar}'  coil,  while  the  last  end  of  the  primary  coil  is 


Fig.  1. 

connected  with  the  spring  support  B.  The  electro-motive 
force  is  conveyed  from  the  battery  through  the  primary 
coil  to  the  spring  support  B  (rheotome),  thence  to  the 
platina-pointed  screw  of  the  governor  D,  and  lastly  to 
the  battery,  making  the  complete  circuit. 

In  the  centre  of  the  coil  and  surrounded  by  the  soft  iron 
wires  is  placed  a  soft  iron  rod.  One  end  of  the  rod  is 
bent  at  right  angles,  so  that  the  hammer  on  the  spring  is 
directly  over  and  can  move  toward  this  soft  iron  rod, 
marked  C.  When  the  vibrating  spring  is  resting  against 
the  platina-pointed  screw  D  and  the  battery  is  connected 
with  the  coil,  the  current,  as  it  passes  over  the  wire  of 
this  primary  coil,  renders  magnetic  both  the  centre  bun- 
dle of  soft  iron  wires  and  the  soft  iron  rod. 

The  magnetism  is  of  sufficient  force  to  attract  the  soft 
iron  hammer  on  the  spring,  and  draw  it  down  or  near  to 
the  magnetized  rod  C. 

This  movement  of  the  spring  severs  the  connection 
between  the  spring  and  the  platina-pointed  screw  D  and 
opens  the  circuit.  The  soft  h-on  rod,  therefore,  loses  its 
magnetism.  The  spring  ceases  to  be  held  down,  its  ten- 
sion being  sufficient  to  raise  it  to  a  horizontal  position, 
where  it  again  rests  in  direct  contact  with  the  platina- 
pointed  screw  D.  Again  the  circuit  is  closed  and  the 
process  as  described  is  repeated  with  inconceivable 
rapidity.  By  the  action  of  the  battery  current  as  it  is 
conveyed  over  the  primary  coil,  and  the  influence  of  the 
magnetized  bundle  of  soft  iron  wires,  a  current  is  induced 
upon  the  second  coil  of  fine  wire  which  surrounds  the 
primar}-  coil.  This  power  of  induction  can  be  established 
to  the  fifth  and  sixth  coil,  and  further  if  the  magnetic  field 
is  properly  arranged. 

In  the  ordinary  form  of  induction  coil  just  described, 
the  terminals  of  the  secondary  or  fine  wire  coil  are  firee 
and  in  no  manner  connected  with  the  primary  circuit. 


5H 


THE   MEDICAL   RECORD. 


[November  8,  1884. 


The  influence  of  magnetism  produces  a  current  which  we 
call  pure  induced. 

In  the  continuous  coil  apparatus,  on  the  contrary,  we 
not  only  receive  the  inductive  influence,  but  the  primary 
influence  as  well,  since  it  is  carried  over  in  combination 
with  the  induced  currents.  Although  called  a  continu- 
ous coil,  it  is  really  made  up  of  8%veral  distinct  coils,  and 
each  successive  coil  increases  in  length  but  decreases 
in  thickness.  These  coils  are  wound  over  each  other, 
and  are  tapped  at  difTerent  portions  of  their  length,  but 
unlike  other  forms,  they  make  direct  connection  with 
each  other.  This  accounts  for  an  apparent  contradic- 
tion of  terms  that  might  prove  confusing. 

These  coils  are  for  convenience  of  illustration  rep- 
resented by  the  upper  straight  lines ,  =,  ^,  =  (Fig. 

2),  termed  respectively  the  primary,  first,  second,  and  third 


note,  however,  that  this  current  has  considerable  chemi- 
cal power.  It  will  burn  iron  or  steel,  giving  forth  a 
bright  deflagrating  spark,  and  will  readily  electro-plate, 
an  effect  not  obtainable  with  any  of  the  induction  coils, 
either  alone  or  in  combination  with  each  other.  This 
current  is  apparently  very  weak,  and  induces  but  slight 
muscular  contractions  in  the  healthy  person.  In  occa- 
sional pathological  conditions,  however,  this  mild  current 
acts  with  unexpected  energy^  producing  muscular  con- 
tractions far  exceeding  in  vigor  those  that  are  called 
forth  by  the  stronger  action  of  the  induction  coils. 

On  account  of  its  mild  but  efficient  action  the  current 
from  the  primary  coil  is  preferable  for  applications  to  the 
head  and  the  more  sensitive  portions  of  the  body,  and  it 
will  as  a  rule  relieve  pains  of  a  true  neuralgic  character,  and 
especially  when  great  tenderness  exists  along  the  course 
of  the  nerve,  far  more  effectually  than 

j  the  current  from  any  of  the  induction 

i  coils.     It  is  impossible  to  account  for 

I  this  frequently  observed  fact,  without 

i  it  be  ascribed  to  a  combination  of  the 


Fig.  a. 

induction  coils.  The  letters  A,  B,  C,  D,  E  represent  the 
different  posts  of  the  continuous  coil  apparatus  to  which 
the  conducting  cords  are  attached,  while  the  numerals  i, 
2,  3,  4,  etc.,  indicate  the  combinations  by  which  are 
obtained  ten  different  qualities  of  current.  The  short 
line  marked  i,  starting  from   A,  represents  the  current 

from  the  short,  thick,  primary  coil  marked .     Second 

line  (2),  current  from  the  primary  and  first  (==) induction 
coils  combined.  Third  line  (3),  current  from  the  primary 
and  first  and  second  (==,  =)  induction  coils.  Fourth 
line  (4),  current  from  primary,  first,  second,  and  third 

f=»  ^>  =)  induction  coils.  Fifth  line  (5),  current 
i-om  the  first  induction  coil  only.  Sixth  line  (6),  cur- 
rent from  the  first  and  second  induction  coils.  Seventh 
line  (7),  current  from  the  first,  second,  and  third  induction 
coils.  Eighth  line  (8),  airrent  from  the  second  induction 
coiL  Ninth  line  (9),  current  from  the  second  and  third 
induction  coils  combined.  Tenth  line  (10),  current  firom 
the  third  induction  coil  only. 

Therapeutical  considerations. — When  we  consider  the 
many  combinations  chat  are  possible  in  the  continuous 
coil  apparatus  and  the  different  qualities  of  current  that 
result  therefrom,  its  general  superiority  over  the  separate 
coil  is  sufficiently  evident ;  and  this  superiority  becomes 
more  marked  if  we  examine  into  the  varied  physical  and 
physiological  effects  produced  by  these  combinations. 

Our  object  of  inquiry,  however,  is  not  as  to  the  rela- 
tive merits  of  different  machines,  but  as  to  the  compara- 
tive value  of  and  the  differential  indications  for  the  use 
of  the  various  combinations  of  the  continuous  coil  appa- 
ratus. This  point  of  inquiry,  although  less  important  than 
when  it  relates  to  the^two  forras-of  dynamic  electricity, 
is  yet  of  no  little  account,  and  in  some  respects  has  been 
found  to  be  more  difficult  of  solution. 

Notwithstanding  the  many  qualities  of  current  that  are 
derived  from  the  continuous  coil,  I  have,  after  much  ob- 
servation, reduced  to  three  the  number  of  combinations 
that  seem  to  be  worthy  of  differential  consideration. 

Every  therapeutic  result  that  can  be  obtained  by  any 
vof  the  ten  combinations  heretofore  considered,  will  in  all 
probability  result  from  the  use  of  some  one  of  the  fol- 
lowing : 

-;^i.  The  current  from  the  primary  coil  as  represented 
by  the  line  marked  i  (Fig.  2). 

2.  The  current  from  the  primary  and  the  first  and 
second  induction  coils  in  combination,  as  represented  by 
the  line  marked  3. 

3.  The  current  from  the  primary  and  the  first,  second, 
and  third  induction  coils  in  combination,  as  represented 
by  the  line  marked  4. 

{TiThe  primary  coil  yields  a  current  of  large  quantity  but 
of  small  tension,  owing  to  the  fact  that  the  wire  of  which 
the^coil  is  composed  is  short  and  thick.     It  is  worthy  of 


battery  and  the  inductive  influence. 
When  dealing  with  an  agent  so  subtle 
and  so  little  understood  as  electricity,  it  is  difl[icult  to  ex- 
press one's  meaning  in  terms  altogether  satisfactory, 
but  that  such  a  combination  is  active  and  effective 
is  evidenced  by  the  readiness  with  which  electrolytic 
effects  are  produced.  Asthenopia  is  a  symptom  diat 
I  have  known  to  be  greatly  relieved  and  even  cured 
many  times  by  electricity,  but  more  especially  through 
the  use  of  the  primary  coil.  The  tired,  aching  eye 
is  both  temporarily  rested  after  each  sitting  and  per- 
manently strengthened  by  continued  treatment.  There 
seems  to  be  little  appreciation,  either  among  ophthal- 
mologists or  general  practitioners,  of  the  great  relief 
that  may  follow  this  treatment  in  the  many  cases  where 
the  eyes  ache  severely,  if  used  even  for  a  little  time 
before  breakfast  or  at  twilight,  or  where  neuralgic  pains 
exist  in  or  near  the  eye,  or  where  there  is  annoyance 
from  muscal  volitantes. 

As  we  include  in  the  circuit  With  the  primary  the  vari- 
ous induction  coils,  the  current  increases  in  strengdi 
with  each  coil  that  is  added.  With  the  addition  of  the 
first  induction  coil  a  much  greater  strength  is  apparent, 
but  the  combination  has  no  marked  physical  or  physio- 
logical effects  that  need  detain  us.  By  including  also 
the  second  induction  coil  in  the  circuit,  however  (line 
marked  3,  Fig.  2),  we  obtain  a  current  of  a  peculiar  and 
unique  quality.  Like  the  primar}-  coil,  it  will  elecu-o- 
plate,  but  unlike  it,  it  will  not  bum  steel  or  iron.  The 
peculiarity  of  this  combination  of  the  coils  is  that  the 
maximum  of  power  to  contract  muscular  tissue  is  here 
obtained.  Each  additional  coil  now  that  is  attached 
simply  gives  a  decreasing  contractile  power.  Why  the 
maximum  of  current  strength  is  reached  in  the  combina- 
tion of  the  primary  with  5ie  first  and  second  induction 
coils  it  is  difficult  to  sayj  excepting  as  we  ascribe  it  to 
the  law  of  harmony  or  polarization  that  is  brought  about 
by  properly  conditioning  the  magnetic  centre  of  the 
helix,  the  several  coils  composing  the  helix,  and  the  bat- 
tery influence  acting  upon  the  coils.  The  current  from 
this  combination  is  not  at  all  pleasant ;  it  is  keen  and 
cutting  in  character,  and  with  its  strong  contractile  prop- 
erties It  is  peculiarly  adapted  to  those  cases  where  pow- 
erful impressions  are  called  for.  Hence  in  not  a  few 
cases  of  paralysis  where  the  response  to  galvanism  is 
perfect,  but  where  there  is  a  diminution  of  farado-mus- 
cular  contractility,  I  have  found  it  preferable  to  any  of 
the  other  qualities  of  current  to  be  derived  from  the  con- 
tinuous coil  apparatus. 

In  superficial  forms  of  anaesthesia  it  is,  perhaps,  in  no 
way  superior,  but  in  certain  persistent  and  more  deeply 
seated  forms  of  lost  or  perverted  sensibility  it  is  decid- 
edly more  efficacious  than  other  combinations.  Its 
greater  contractile  power  over  muscular  tissue,  both  vol- 
untary and   involuntary,  renders  it   most   efficacious  in 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


515 


cases  of  menstrual  suppression,  and  also  for  atrophied 
conditions  of  the  utenis,  for  which  so  much  has  been  done 
by  electrical  methods  of  treatment.  In  cases  of  dysmen- 
orrhoea,  as  well  as  in  the  various  neuralgias,  my  experi- 
ence leads  ine  to  exclude  its  use.  Faradism  has  been 
used,  and  with  success,  to  destroy  the  foetus  in  extra-uter- 
ine pregnancy.  While  I  greatly  prefer  the  galvanic  cur- 
rent, having  always  used  it  without  the  slightest  ill  effect, 
yet  if  the  faradic  is  employed  I  should  not  recommend 
the  current  from  the  coils  now  under  consideration,  but 
the  one  presently  to  be  described ;  for  with  this  latter 
form  we  obtain  effects  equally  destructive  to  the  foetal 
life  and  with*  less  violence  to  the  contractile  tissues  of 
the  mother.  There  are  several  other  differential  points 
connected  with  the  use  of  this  series  which  suggest  them- 
selves, but  they  are  of  minor  importance. 

When  we  include  in  the  circuit  not  only  the  primary 
and  the  first  and  second,  but  also  the  third  induction  coil 
as  represented  by  the  line  marked  4,  effects  are  obtained 
more  interesting  and  satisfactory  than  from  any  of  the 
other  combinations. 

These  effects  are  pre-eminently  tonic  and  sedative  in 
character,  and  give  for  this  quality  of  current  a  range  of 
usefulness  wider  than  can  be  ascribed  to  the  others.  There 
are  but  few,  in  all  probability,  who  at  this  day  are  unfa- 
miliar with  the  term  general  faradization,  and  who  do  not 
understand  that  by  it  is  meant  the  application  of  the 
faradic  current  to  the  entire  surface  of  the  body,  from 
the  crown  of  the  head  to  the  soles  of  the  feet.  It  is  in  the 
operation  of  general  faradization,  when  we  desire  to  ob- 
tain the  best  constitutional  tonic  effects  that  electricity 
is  capable  of  giving,  that  we  resort  to  this  combination 
of  the  primary  and  induction  coils.  Its  action  on  the 
motor  and  sentient  nerves  is  less  severe,  and  its  general 
effects  far  more  agreeable.  For  the  relief  of  that  great 
army  of  symptoms  that  are  so  familiar  and  so  perplexing 
to  those  who  have  had  much  to  do  with  neurasthenic  cases, 
there  is,  according  to  my  experience,  nothing  to  be  com- 
pared with  it  Even  the  galvanic  current  by  the  method 
of  central  galvanization,  so  important  in  its  direct  effect 
upon  the  central  nervous  system,  falls  short  of  the  thera- 
peutic results  that  follow  well-directed  applications  ;of 
general  faradization.  When  persistent  failure  follows 
endeavors  along  this  line  of  electrization,  the  cause  of 
failure  must  be  ascribed  to  hasty  and  faulty  methods  of 
administration.  In  no  department  of  therapeutics  is  it 
of  more  importance  to  be  thorough  in  detail.  He  only 
will  achieve  the  best  results  who  appreciates  this  fact, 
who  is  willing  to  inform  himself  as  to  the  modus  operandi 
of  the  methods,  and  who  will  devote  in  individual  cases 
a  reasonable  degree  of  time  and  patience  in  carrying 
them  out. 

An  Antipyretic  Formula. — The  following  is  recom- 
mended by  Dr.  de  Giovanni  as  a  substitute  for  quinine,  in 
which  the  latter  is  ineffective  or  injurious  in  its  effects 
(Rivista  Clinica,  No.  8, 1884) :  Ergotine  (Bonjean),  fifteen 
grains ;  tincture  of  valerian,  half  an  ounce ;  water,  three 
ounces ;  to  be  taken  during  the  height  of  the  fever  or  in 
the  period  of  remittance.  Usually  the  good  effects  are 
obtained  after  one  or  two  doses,  but  the  remedy  should 
be  continued  for  some  time  after  the  subsidence  of  the 
fever.  In  rebellious  cases  the  author  substituted  with  bene- 
fit cherry-laurel  water,  one-half  to  one  drachm,  for  the 
valerian.  The  best  results  were  obtained  in  intermittent 
fevers,  but  good  effects  were  seen  also  in  remittents,  in 
the  hectic  of  incipient  phthisis,  and  even  in  puerperal 
fever. 

Bicarbonate  of  Soda  in  Iodoform  Poisoning. — Dr. 
Behring  states  that  bicarbonate  of  soda  is  an  antidote  in 
poisoning  from  iodoform.  Since  the  latter  drug  is  elimi- 
nated in  the  urine  as  an  iodic  salt,  the  author  assumes 
that  it  abstracts  alkalies  from  the  blood.  By  supplying 
the  alkali  thus  withdrawn  from  the  blood  he  believes 
that  the  system  may  acquire  a  special  toleration  for  iodo- 
form.— Rivista  C/inica,  No.  8,  1884. 


poetess  of  "l^j^&imX  J^cietxce. 

German  Measles. — It  appears  to  be  a  somewhat 
general  opinion  that  RStheln,  or,  as  it  is  not  infrequently 
called,  German  measles,  is  a  disease  of  such  minor  im- 
portance as  to  be  unworthy  of  scientific  research ;  but  a 
disease,  the  victims  of  which  succumb  as  early  as  the 
fourth  day,  must  be  of  sufficient  importance  to  demand 
our  attention  and  the  best  efforts  of  our  armamentarium. 
Dr.  W.  A.  Edwards,  during  the  winter  and  spring  of 
1 88 1-2,  studied  in  the  Philadelphia  Hospital  over  one 
hundred  cases  of  the  disease,  and  the  results  of  his 
observations  he  details  in  a  paper  in  the  October  number 
of  TAe  American  Journal  of  the  Medical  Sciences.  As 
regards  the  diagnosis,  he  says  the  eruption  appearing 
on  the  third  day,  first  in  the  face,  its  rapid  extension,  its 
gradual  shading  off  into  the  surrounding  skin,  its  eleva- 
tion, more  particularly  in  the  centre  of  the  patch,  which 
is  also  the  brightest  in  color,  together  with  the  fact  that 
desquamation  first  shows  itself  there,  are  all  points  which, 
as  far  as  the  eruption  is  concerned,  render  the  diagnosis 
plain ;  furthermore,  the  rash  almost  at  once  occupied  the 
whole  body,  and  never  presented  a  crescentic  outline. 
The  extreme  drowsiness  during  the  eruptive  stage  is  a 
symptom  upon  which  Cheadle  lays  some  stress.  It  is 
Dr.  J.  M.  Keating' s  experience  that  however  severe  the 
attack  may  be,  or  how  diffused  the  eruption,  the  contour 
of  the  face  is  never  lost,  and  that  by  looking  properly 
you  can  always  see  the  zygomatic  arch ;  this,  he  observes, 
is  always  obliterated  in  cases  of  either  measles  or 
scarlatina  that  are  severe  in  character.  Sore  throat  was 
always  present ;  in  scarlatina  it  is  directly  in  proportion  to 
the  type  and  severity  of  the  disease ;  the  more  laryngeal 
characterof  the  cough  in  Rotheln  is  also  worthy  of  note. 
The  pulse  remains  low,  that  is,  much  lower  than  a  case  of 
like  severity  of  either  measles  or  scarlatina.  The  fact 
that  Rotheln  propagates  itself,  and  never  gives  rise  to 
either  measles  or  scarlatina,  and,  moreover,  does  not 
protect  from  these  diseases,  is  a  further  diagnostic  point 
that  should  claim  our  attention.  Dr.  Edwards  highly 
recommends  the  application  of  oleaginous  preparations 
to  the  skin  during  the  stages  of  eruption  and  desquama- 
tion ;  in  the  former  stage  for  the  comfort  of  the  patient, 
and  to  allay  itching  and  aid  in  the  reduction  of  the  tem- 
perature; in  'the  latter,  to  prevent  contagion,  as  all  of 
his  cases  underwent  desquamation,  and  in  all  probability 
the  contagion  is  carried  by  these  fine  scales. 

lODOFORM-FORMING    BODIES     IN    THE     EXPIRED    AlR 

OF  Diabetics. — As  is  well  known,  Fetters,  Kaulich,  and 
others  have  found  acetone,  revealed  by  its  peculiar  odor, 
in  the  expired  air,  the  urine,  and  the  blood  of  diabetics. 
Later  investigations  have  proved  its  presence  in  the 
urine  by  chemical  i^eactions,  but  methods  for  recognizing 
it  in  the  expired  air  were  less  available.  Several  new 
acetone  reactions  having  been  recently  discovered,  Dr. 
Nobel  attempted  to  reach  results  more  accurate  than 
have  been  hitherto  obtained.  The  urine  of  the  diabetic 
patient  contained  no  acetone  on  examination,  but  some 
days  after  an  exclusive  fish-diet  was  begun  it  contained 
large  quantities.  The  expired  air  was  thus  examined. 
It  was  first  conducted  into  a  WolfiPs  bottle,  filled  with 
distilled  water,  and  after  half  an  hour  a  solution  of  iodine 
in  iodide  of  ammonium  and  liquor  ammoniae  was  added. 
By  the  next  day  a  yellow  precipitate  was  seen  at  the 
'  bottom  of  the  flask,  which  on  microscopic  examination 
showed  the  iodoform  tablets  most  clearly.  On  the  other 
hand;  the  urine  of  another  diabetic  patient,  which  only 
gave  a  weak  acetone  reaction,  showed  only  a  slight 
separation  of  iodoform.  On  another  occasion  the  air 
was  passed  through  the  water  for  an  hour,  the  latter  was 
distilled  for  six  hours  in  a  water  bath  at  146.4^  F.,  and 
the  distillate  was  divided  into  three  equal  portions.  To 
one  the  above-mentioned  test  solution  was  added,  and  a 
copious  precipitate  of  iodoform  obtained.     To  the  sec- 


516 


THE   MEDICAL  RECORD. 


[November  8, 1884. 


ond  a  (ew  drops  of  mercuric  chloride  were  added,  and 
then  enough  caustic  potash  to  render  it  alkaline  ;  it  was 
then  filtered  and  ammonium  sulphide  added  ;  this  caused 
a  black  precipitate  of  sulphide  of  mercury  ^Gunning's  re- 
action).    The  third  portion  yielded  a  positive  result  with 
sodium  nitro-cyanide  and  liquid  ammonia  (the  acetone 
test  of  the  author).     No  doubt  remained  that  the  iodo- 
form-making  substance  was  acetone.      Continued  dis- 
tillation for  an  hour  gave  no  more  acetone,  though  the 
iodoform  reaction  revealed  jj^^jny  milligr.     On  another 
occasion    the    distillation   was   made    at   the   tempera- 
ture of  1 76°  F. ;    and   after  twelve  hours   the  neutral 
distillate,  which  gave  distinctly  the  iodoform  reaction, 
was  treated  with  spongy  platinum,  and  the  presence  of 
acetyl-aldehyde  at  the  beginning  of  oxidation  was  proved 
by  the  reduction  of  ammonia-silver  solution,  and  by  the 
color-test  of  the  author  (sodium  nitro-cyanide,  caustic 
potash,  and  acetic  acid).     By  further  oxidation  acetic 
acid  was  formed,  which  reddened  blue  litmus-paper  held 
over  it ;  by  careful  neutralization  with  very  dilute  caustic 
soda,  a  red  color,  which  was  destroyed  by  dilute  sulphuric 
acid,  was  .obtained  with  ferric   perchloride.     Thus,  be- 
side acetone,  ethyl-alcohol  was  found  in  the  air  expired 
by  this  patient.     Regarding  the  destiny  of  alcohol  in  the 
animal  organism,  according  to  some  it  is  oxidized  for  the 
most  part,  and,  therefore,  must  have  a  nutritive  value ; 
while,  according  to  others,  the  greater  part  of  it  is  ex- 
creted,   unaltered,   by   the    kidneys,    skin,   and    lungs. 
However  this  may  be,  it  is  evident  that  no  conclusioji 
can  hence  be  drawn  as  to  its  behavior  in  the  bodies  of 
diabetics,  in  whom  the  oxidation-processes  are  altered 
so  much  owing  to  irregular  tissue-changes.     The  alcohol 
formed  in  such  subjects  may  possibly  be  excreted  un- 
altered for  the  most  part,  which  would  agree  with  the 
above  results. — London  Medical  Record^  August  15,  1884, 
Cholkcystotomy. — In  The  American  Journal  of  the 
Medical  Sciences  for  October,  1884,  Drs.  J.  H.  Musser  and 
W.  W.  Keen  publish  an  article  on  cholecystotomy,  in 
which  they  relate  two  new  cases,  with  a  table  of  all  the 
hitherto  reported  cases,  thirty-five  in  number.     The  first 
case  was  that  of  a  man,  aged  thirty-two,  who  had  had 
attacks  of  biliary  colic  for  five  years,  followed  by  jaun- 
dice, until  he  was  reduced  in  strength,  and  had  chills  and 
fever  threatening  life.     Dr.  Keen  attempted   cholecys- 
totomy,  the  incision  being  made  over  a  region  of  dulness 
believed  to  be  the  gall-bladder.     This  dulness  was  found 
tp  be  due  to  an  inflammatory  mass,  which  glued  together 
the  gall-bladder,  colon,  and  intestine.     No  stone  could 
be  detected.     The  wound  was  closed,  and  recovery  ulti- 
mately followed  a  course  of  Hathorn  water  at  Saratoga. 
The  second  case  was  also  that  of  a  man,  aged  thirty-one, 
with  acute  gastro-intestinal  catarrh,  followed  by  jaundice, 
enlarged  gall-bladder,  and  symptoms  of  internal  suppura- 
tion.    The  enlargement  of  the  gall-bladder  was  demon- 
strated by  the  hypodermic  needle,  but  the  fluid  was  not 
bile.    Dr.  Keen  performed  cholecystotomy,  using  a  large 
hollow-handled  spatula  to  drain  off  the  twenty  ounces  of 
fluid  contained  in  the  gall-bladder.    The  gall-bladder  was 
found  to  be  seven  inches  in  depth,  but  neither  by  finger 
nor  probe  could  any  gall-stone  or  the  orifice  of  the  duct 
be  found.     A  biliary  fistula  was  established,  and  bile  was 
discharged  through  it  the  next  day.     The  patient  died  a 
week  later  of  exhaustion.    The  post-mortem  examination 
revealed  inflammatory  closure  of  the  cystic  and  common 
ducts  at  the  mouth  of  the  gall  bladder  and  at  the  duo- 
denum.    Dr.  Musser  in  his  medical  comments  analyzes 
at  length  the  causes,  symptoms,  and  diagnosis  of  biliary 
obstruction,  under  the  heads  of  jaundice,  tumor,  pain, 
and  suppuration,  especially  in  relation  to  gall-stones  .and 
other  foreign  bodies  and  diseases  of  the   ducts.     He 
points  out  the  means  by  which  a  just  conclusion  may  be 
reached,  and  that  cholecystotomy  should  be  resorted  to 
early  in  the  case  rather  than  wait  till  the  blood  is  disor- 
ganized and  the  liver  softened  and  made  functionally 
useless.     Especially  is  this  true  in  view  of  the  low  mor-  j 
tality  of  the  operation,  there  having  been  (excluding  ' 


Gross'  incidental  case)  only  nine  deaths  in  thirty-four 
operations,  and  of  the  fact  that  Mr.  Tait  has  done  thir- 
teen operations,  by  far  a  larger  number  than  any  other 
operator,  all  of  which  have  been  successful.  In  his  sur- 
gical comments,  Dr.  Keen  discusses  the  surgical  means 
of  diagnosis  by  aspiration,  with  or  without  probing  through 
the  canula,  and  by  acupuncture,  both  of  which,  when 
properly  done,  he  commends.  He  also  strongly  urges 
an  early  laparotomy,  followed  at  once  by  cholecystotomy, 
if  found  advisable,  and  condemns  the  attempt  to  provoke 
or  to  wait  for  adhesions.  Indeed,  upon  this  disregard  of 
adhesions  hinges  the  whole  of  our  modem  progress  in 
abdominal  surgery.  He  points  out  that  to  Bobbs,  of 
Indiana,  and  to  Sims,  both  American  surgeons,  is  due 
the  credit  of  first  performing  and  practically  perfecting 
the  operation.  He  advises  the  formation  of  a  biliaiy 
fistula,  rather  than  sewing  up  the  gall-bladder,  and  dis- 
approves, as  a  rule,  a  removal  of  the  gall-bladder,  as  add- 
ing a  new  and  usually  a  needless  danger. 

Dyspeptic  Coma. — Dr.  Riess  has  observed  a  number 
of  cases  resembling  in  their  principal  features  the  picture 
depicted  by  Kussmaul  of  diabetic  coma.  But  in  no  in- 
stance was  there  any  glycosuria,  the  coma  occurring  with 
anaemia,  nephritis,  and  carcinoma  of  the  liver  and  stom- 
ach. In  almost  every  case  the  chloride  of  iron  test  gave 
negative  results,  showing  that  the  trouble  was  not  due  to 
poisoning  with  acetones.  The  author  concluded  that  the 
symptoms  of  diabetic  coma,  for  which  he  proposes  the 
name  of  dyspnoeic  coma,  may  be  also  excited  by  a  falling 
off  in  the  proportionate  number  of  red  blood-corpuscles. 
Dr.  Litten  has  observed  the  characteristic  chloride  of 
iron  reaction  of  the  urine  in  twenty-five  non-diabetic 
patients,  and  concludes  that  it  may  be  found  exception- 
ally with  any  disease.  In  only  one  of  these  cases  did  he 
observe  the  dyspnceic  coma  of  Kussmaul.  He  saw,  how- 
ever, several  cases  in  which  there  was  the  peculiar  odor 
of  the  breath  and  a  soporific  condition,  but  without  any 
of  the  respiratory  disturbances  described  by  Kussmaul. 
He  thought,  nevertheless,  that  the  two  conditions  were 
essentially  the  same,  and  were  caused  by  poisoning  from 
some  substance  produced  in  the  digestive  canal.  This  is 
probably  the  same  substance  to  which  is  owing  the  pe- 
culiar odor  of  the  breath  and  the  characteristic  reaction 
of  the  urine.  This  was  supposed  to  be  ethyldiacelic 
acid,  but  Frerichs  denies  the  identity  of  the  two  sub- 
stances.— Allgemeine  Medicinische  Central'2^iiungy  No. 
6Z,  1884. 

The  Physiological  Action  of  Digitalis. — In  the 
October  issue  of  The  American  Journal  of  the  Medical 
Sciences   Dr.    Nickles,    of  Cincinnati,    summarizes  the 
present   state   of  our*  knowledge   of  the   physiological 
action   of    digitalis.       The   doctrines    now   universally 
taught  regarding  the  action  and  uses  of  digitalis  differ  in 
a  number  of  important  points  from  those  held  two  decades 
ago.    Then  we  were  taught  that  digitalis  is  essentially 
a  sedative,  affecting  strongly  the  nervous  system,  thus 
causing  feeble  and  slow  heart  action.     Now  the  latest 
authors  teach  that  the  nervous  system  is  only  secondarily 
affected,  while  the  heart  is  directly  influenced,  its  action 
becoming  more  powerful  though  slower.     Twenty  years 
ago  we  were  taught  that  digitalis  is  a  diuretic,  directly 
acting  upon  the  kidneys,  thus  producing  in  many  diseases 
a  greater  secretion  of  urine.     To-day  we  are  told  that 
digitalis  does  not  act  upon  the  kidneys  at  all,  and  only 
secondarily  affects  the  secretion  of  urine  by  causing  a 
change  in  the  systemic  circulation.     In  one  point,  there 
is  universal  agreement,  that  digitalis  recklessly  used  may 
produce  the  most  disastrous  effects,  and  that  these  may 
occur  quite  unexpectedly  in  consequence  of  cumulative 
action.     But  not  only  in  regard  to  the  modus  operandi 
do  present  authors  differ  from  their  predecessors,  but 
also  as  to  the  therapeutic  indications.     Two  decades  ago 
digitalis  was  held  to  be  indicated  when  the  heart's  action 
is  too  powerful ;  now  we  are  informed  that  it  is  useful 
only  when  the  heart's  action  is  too  feeble.     Then  author 


November  8,  1884.] 


THE 'MEDICAL  RECORD. 


517 


taught  that  digitalis  will  control,  and  hence  favorably 
influence,  a  hypertrophied  heart,  while  present  writers 
contend  that  every  disease  of  the  heart  attended  with 
excessive  action  is  aggravated.  It  was  held  for  a  century 
that  digitalis,  though  not  eminently  useful,  is  still  often  of 
great  service  in  dropsy  dependent  upon  organic  disease 
of  the  kidneys ;  but  now  we  hear  that  in  diseases  of  the 
kidney,  attended  with  diminished  diuresis,  it  is  almost 
always  useless,  and  always  exceedingly  dangerous. 

Mumps  as  a  Cause  of  Sudden  Deafness. — Disease 
of  the  ear  during  the  progress  of  acute  infectious  disor- 
ders is  a  not  infrequent  occurrence.  Especially  are 
suppurative  inflammations  of  the  middle  ear  common 
during  the  progress  of  scarlet  fever,  and  non-suppurative 
inflammations  are  a  frequent  attendant  upon  the  progress 
of  measles.  The  nature  and  treatment  of  these  ear  dis- 
eases are  well  understood.  But  occasionally  during  the 
progress  of  mumps  a  sudden  and  complete  loss  of  hear- 
ing occurs  which  is  not  so  well  known,  either  as  to  its 
nature  or  its  treatment.  A  paper  on  the  subject  from 
the  pen  of  Dr.  Leartus  Connor^  of  Detroit,  which  appears 
in  the  October  number  of  The  American  Journal  of  the 
Medical  Sciences^  gives  the  following  conclusions :  i. 
Parotitis  in  some  rare  cases  produces  complete  deafness ; 
2,  this  deafness  is  usually  attended  with  all  the  evidences 
of  disease  of  the  labyrinth  ;  3,  these  show  that  it  some- 
times begins  in  the  cochlea,  but  more  frequently  in  the 
semicircular  canals  ;  4,  owing  to  the  lack  of  early  observa- 
tions and  treatment  it  is  impossible  to  say  that  it  is  not 
transmitted  through  the  middle  ear  from  the  parotids  to 
the  labyrinth  ;  5,  the  history  of  some  of  the  cases  would 
seem  to  suggest  that  such  an  origin  was  possible ;  6, 
this  possibility  renders  it  very  important  that  every  case 
of  deafness  during  an  attack  of  mumps  be  at  once  care- 
fully examined,  so  as  to  settle  the  question  ;  7,  this 
possibility  offers  the  only  hope  for  the  successful  treat- 
ment of  these  cases  so  as  to  prevent  deafness.  Thus,  if 
there  be  a  middle-ear  disease,  we  might  hope  that  revul- 
sive and  counter-irritant  treatment  would  arrest  the  dis- 
ease and  save  the  labyrinth  ;  S,  as  to  treatment  of  the 
labyrinthine  disease  nothing  has  thus  far  been  devised 
that  has  produced  any  satisfactory  result. 

Grave  Nervous  Symptoms  Occurring  in  Typhoid 
Fever. — Dr.  Baas  relates  the  case  of  a  boy  eight  and  a 
half  years  old,  who  was  suffering  from  typhoid  fever.  At 
the  twentieth  day,  when  the  fever  was  at  its  maximum, 
the  child  passed  some  bloody  stools,  and  at  the  same 
time  fell  into  a  state  of  complete  cerebral  torpor.  The 
patient  gave  no  signs  of  consciousness,  the  pupils  were 
contracted  and  responded  very  sluggishly  to  light,  and 
there  were  several  convulsive  attacks  limited  to  the  right 
side  of  the  face.  The  following  day  there  was  paralysis 
of  the  right  facial  nerve  and  of  the  arm  on  the  same  side. 
The  fever  began  tor  subside  at  this  time,  consciousness 
slowly  returned,  and  the  paralysis  disappeared.  But  with 
the  return  of  consciousness  the  child  was  found  to  be 
aphasic  and  agraphic.  He  understood  what  was  said  to 
him,  but  was  unable  to  find  the  words  to  reply.  On  at- 
tempting to  write  he  could  only  trace  some  meaningless 
figures  which  he  himself  recognized  as  expressing  nothing. 
For  a  few  days  he  was  unable  even  to  indicate  his  desires 
by  appropriate  gestures.  He  could  not  count,  but  would 
point  with  his  finger  to  the  number  which  he  was  not 
able  to  articulate.  Five  weeks  after  the  beginning  of 
paralysis  he  began  to  speak,  articulating  first  the  vowels 
and  later  the  consonants.  One  month  later  he  had  en- 
tirely recovered.  These  symptoms  seemed  referrible  to 
lesions  in  the  third  frontal  convolution  on  the  left  side, 
and  in  the  motor  centres  of  the  cortex.  The  author 
believed  that  they  were  caused  by  a  capillary  apoplexy. 
—Archives  Gendrales  de  Midecine^  September,  1884. 

The  Varieties  of  Purpura. — The  pathogenesis  of 
purpura  is  as  yet  involved  in  considerable  obscurity.  In 
a  recent  study  of  the  subject.  Dr.  Leloir  {Annales  de 
Dermatologie  el  de  Syphiligraphie)  recognizes  three  main 


groups  of  this  affection  :  A,  Purpura  from  modification 
of  the  vessels. — i.  From  perturbation  of  the  capillary 
circulation,  whatever  its  origin,  leading  to  active  or  pas- 
sive hyperaemia,  producing  hemorrhage  by  diapedesis  or 
by  vascular  rupture.  2.  Purpura  lUangiecicLsique  of 
Cornil.  3.  Purpura  from  primary  alteration  of  the  vas- 
cular walls,  and  consecutive  rupture  of  these  walls.  B. 
Purpura  from  modifications  of  the  blood. — i.  Too'  great 
fluidity  of  the  blood  (purpura  by  diapedesis).  2.  From 
vascular  obstructions  determined  by  certain  elements 
contained  in  the  blood  leading  to  the  formation  of  throm- 
boses and  embolisms.  This  purpura  might  occur  from 
simple  diapedesis  ;  it  is  more  often  hemorrhagic  infarction 
of  the  skin,  a.  From  formation  of  clots  in  blood-dys- 
crasiae.  b.  From  embolism  formed  by  white  corpuscles 
(leucocythaemia,  etc),  c.  From  embolisms  formed  by 
bacteria  or  micrococci  (septic  diseases,  etc.).  d.  From 
embolisms  formed  by  altered  blood-elements.  C  Pur- 
pura nervosa.  In  practice,  however,  many  cases  will 
not  fall  completely  into  either  group  ;  very  often  the  ori- 
gin seems  to  be  complex.  Alteration  of  the  blood,  trou- 
bles of  the  circulation,  vascular  lesions,  disturbances  of 
innervation,  all  causes  of  cutaneous  hemorrhage,  may  co- 
exist in  the  same  subject.  In  all  probability,  even  dys- 
crasic  purpura  may  be  in  certain  cases  the  origin  of  sec- 
ondary vascular  lesions,  of  secondary  endarteritis.  And 
it  is  probable  that  alteration  of  the  bloo,d  often  modifies 
the  action  of  the  vaso-motor  nervous  apparatus,  central 
or  peripheral.  In  studying  a  case  of  purpura,  it  must 
not  be  forgotten,  then,  that  its  pathogenesis  may  be  com- 
plex. The  relative  importance  of  the  different  causes 
must  be  sought ;  and  an  attempt  must  be  made  to  deter- 
mine the  relations  between  the  determining  primary  or 
predisposing  causes  and  the  occasional  or  secondary 
causes. 

Iodized  Collodion  in  Erysipelas. — Dr.  Humphreys, 
of  Texas  {NcLshville  Journal  of  Medicine  and  Surgery y 
September,  1884),  has  used  for  the  past  five  years  iodized 
collodion  as  a  local  application  in  erysipelas.  He  has 
had  uniform  success  with  it,  even  in  quite  obstinate  cases. 
Constitutional  treatment  is,  however,  not  neglected  by 
him.  The  collodion  is  applieo  with  a  feather  or  camel' s- 
hair  brush,  as  often  as  desirable  (?).  Upon  evaporation 
of  the  ether  there  is  a  feeling  of  coolness  and  ease,  after 
days  and  nights  of  suffering.  The  following  formula  for 
making  the  iodized  collodion  is  taken  from  IValzPs  FhotO' 
graphic  Rays  of  Lights  January,  1878. 

g.    Sulphuric  ether |  x. 

Alcohol,  absolute |  x. 

Gun  cotton 3  ij. 

Mix,  and  when  dissolved  add 

Iodine  ammonium grs.  80. 

Iodide  cadmium grs.  40. 

Bromide  cadmium grs.  40. 

Mix,  and  bottle  tightly  for  use. 
As  the  salts  of  cadmium  may  not  be  readily  obtained 
in  country  drug  stores,  it  is  highly  probable  that  two 
drachms  iodide  ammonium  and  two  scruples  bromide 
potassium  or  ammonium  added  to  the  first  three  articles 
would  prove  as  efficient  as  the  formula  given  above. 

Atropine  in  Acute  Otitis  Media  of  Child- 
hood.— Dr.  Miot  has  obtained  excellent  results  in  ear- 
ache of  children  from  atropine.  The  children  to  whom 
he  gave  it  were  very  subject  to  coryza,  and  the  inflamma- 
tion would  usually  pass  from  the  nose  to  the  fauces  and 
middle  ear.  But  when  atropine  was  given  at  the  very 
commencement  of  the  rhinitis  the  children  were  spared 
the  pain  of  the  otitis.  For  a  child  he  used  a  solution 
of  sulphate  of  atropine,  i  milligramme  to  80  grammes 
of  water  (^  grain  to  20  drachms),  the  dose  of  which  was 
a  teaspoonful  repeated  from  two  to  four  times  a  day  at 
intervals  of  two  or  three  hours.  For  adults  he  prescribed 
a  dose  of  double  this  strength.  The  treatment  was  con- 
tinued usually  for  two  or  three  d^c^s.—Journal  de  Mide- 
cine  et  de  Chirvrgie  Pratiques y  September,  1884. 


5i8 


THE  MEDICAL  RECORD. 


[November  ^,  i884» 


The  Medical  Record: 


A  Weekly  Journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Ufayette  Place. 

New  York,  November  8,  1884. 


THE   HISTORY   AND   PROPERTIES   OF   CO- 
CAINE. 

Wackenroder  and  Johnston  expressed  the  belief,  as 
long  ago  as  1853,  that  an  active  alkaloid  existed  in  the 
leaves  of  erythr65cylon  coca.  Gadeke  first  isolated  it, 
but  it  was  not  till  i860  that  Niemann  {Ann,  Chem. 
Pharm,^  114,  213)  announced  its  physical  properties  and 
gave  it  the  name  of  cocain,  A  little  later  Losson  found 
in  coca  leaves  another,  apparently  inert,  volatile  base, 
which  he  called  hygrin  {Ann,  Chem,  Pharm,^  133,  351). 
This  latter  chemist  states  that  in  the  best  leaves  the 
amount  of  cocaine  was  at  most  one-fifth  of  one  per  cent., 
and  in  the  poorer  kinds  as  little  as  one-sixtieth  of  one  per 
cent. 

Cocaine  crystallizes  in  large  four  to  six-sided  colorless 
prisms.  It  has  a  bitter  taste,  benumbing  the  tongue,  a 
strongly  alkaline  reaction,  and  melts  at  98®  C.  It  dis- 
solves in  704  parts  of  water  at  12®  C,  easily  in  alcohol, 
and  more  easily  in  ether.  Its  composition,  as  deter- 
mined by  Losson,  is  C„H,jNO^. 

Cocaine  unites  easily  with  dilute  acids  to  form  crys- 
tallizable  salts,  which  are  soluble  in  alcohol  but  not  in 
ether. 

The  salts  which  the  industry  of  chemists  have  already 
prepared  are  the  muriate  (C„H,jNO^HCl),  the  sul- 
phate, nitrate,  tannate,  and  oxalate.  Besides  these  there 
have  been  prepared  double  salts  of  cocain-platinum  chlo- 
ride (C„H„NO,HClPtCl,)  and  of  cocain-gold  chloride. 

By  decomposition  with  strong  acids  a  new  base  has 
been  formed  out  of  cocaine,  which  is  called  ecgonin. 

A  test  given  for  watery  solutions  of  muriate  of  cocaine 
is  picric  acid,  which  throws  down  yellowish  precipitate. 

The  alkaloid  cocaine  has  not  been  used  medicinally 
to  any  great  extent,  but  its  physiological  action  has  been 
studied  by  a  number  of  observers. 

For  man  the  dose  runs  from  one-sixth  to  two  grains. 
Its  lethal  power  is  slight  and  its  action  is  not  cumulative 
(Husemann).  Von  Anrep  found  (Archiv.  ges,  Physiol, ^ 
21,  38,  1880)  that  the  cocaine  could  be  taken  daily  for  a 
long  time  without  producing  any  notable  disturbance, 
and  he  concluded  that  its  action  was  not  cumulative. 
Schroff,  who  in  1862  made  the  first  experiments  upon  man 
with  cocaine  {Zeiischrifi  f,  Wien,  Aerzte^  30-34),  found 
that  in  large  doses  it  caused  vertigo,  lassitude,  slight  deaf- 
ness, disturbance  of  memory,  and  of  co-ordination  of 
thought. 

Other  experiments  and  observations  by  Froumiiller 


{Prag.  [^terteljahrsschr.^  [79,  109,  1863),  Jarchanoff 
("  Cocain  and  Diabetes,  Petersburg,  1872),  and  Ploss 
{Zeiischr,  Chir.^  222, 1863),  appear  to  show  that  cocaine 
is  a  narcotic,  having  a  primary  stimulating  action  upon 
the  brain,  and  being  analogous  in  properties  to  cannabis 
indica.  Froumiiller,  in  fourteen  cases,  was  able  to  pro- 
duce sleep  by  giving  large  doses  (up  to  five  grains). 
Ploss  reports  the  case  of  a  druggist  who  took  about 
twenty- two  grains  of  cocaine  in  a  glass  of  beer.  He  slept 
quietly  for  some  hours,  then  awoke  with  powerful  ab- 
dominal gripings,  burning  and  dryness  of  the  mouth,  and 
thirst.  He  vomited  any  liquid  drank.  He  suffered  fi-om 
vertigo,  feebleness,  and  aneuria  for  twenty-four  hours. 
The  heart's  action  showed  no  disturbance,  and  his  mind 
was  not  disordered.  The  case  is  instructive  as  showing 
that  cocaine  is  probably  not  a  very  poisonous  drug  to 
men,  and  that  in  large  doses  its  narcotic  action  is  imme- 
diate. 

Among  animals  it  has  been  found  that  frogs  are  more 
susceptible  than  warm-blooded  animals,  and  that  car- 
nivora  are  more  sensitive  than  herbivora. 

The  fatal  dose  for  a  dog  is  from  three  to  five  grains 
(Danini :  **  Ueber  Physiolog.  Wirkung  und  Therap.  An- 
wendung  des  Cocains,'*  St.  Petersburg,  1873).  Rabbits 
are  killed  by  doses  of  o.  i  gramme  per  kilogramme  of 
animal,  according  to  Von  Anrep. 

The  physiological  effects  of  cocaine  externally  and 
internally  have  been  studied  by  the  authors  already 
quoted,  and  by  Nikolsky  ("  Beitrag.  zur  Cocain  Wirkung 
auf  den  Thier  Organismus,"  St.  Petersburg,  1872) ;  Isaac 
Ott  (Moreno  y  Maiz :  "  Recherches  Chim.  et  PhysioL 
sur  I'Erythroxylon  Coca  du  P^rou  et  la  Cocaine,"  Paris, 
1868) ;  by  Danini  ("  Ueber  Physiol.  Wirkung  u.  ther. 
Anwendung  des  Cocains,"  Charkow,  1873)  ;  Bennett 
("  Report  on  Antagonism  of  Drugs,"  1875) ;  ^^^  ^Y  ^^^ 
bach  ("R.  and  Nothnagel's  Handbook  of  Therapeu- 
tics"). An  excellent  review  of  the  contributions  of 
these  authors,  to  which  we  are  indebted,  is  given  in 
Husemann  and  Hilger's  "Die  Pflanzenstoffe,"  Berlin, 
1883,  from  which  we  summarize  the  knowledge  so  far 
gained  of  the  properties  of  the  drug. 

Locally,  it  produces  the  effects  upon  skin  and  mucous 
membrane  which  have  been  already  described  in  The 
Record,  and  need  not  be  repeated  now.  Moreno,  in 
1868,  showed  that  local  injections  abolished  reflex  move- 
ments for  a  time,  and  Von  Anrep,  in  1880,  showed  that 
the  sensibility  of  the  skin  was  abolished  when  hypodermi- 
cally  injected^  and  that  of  the  tongue  when  touched  with 
strong  solutions.  The  same  author  applied  a  solution 
containing  one-half  "a  milligramme  to  the  conjunctiva, 
and  found  that  it  caused  a  temporary  dilatation  of  the 
pupil,  which  was  increased  by  adding  atropine.  Strangely 
enough,  Anrep  did  not  note  that  the  conjunctiva  was  in- 
sensible, or  if  so,  did  not  appreciate  the  practical  signifi- 
cance of  the  fact  As  Nikolsky  found  that  the  pupil  is 
still  dilated  by  cocaine  after  section  of  the  sympathetic, 
it  is  inferred  that  the  drug  does  not  act  upon  the  iris 
through  that  nerve. 

Cocaine  given  internally  in  small  doses  to  warm- 
blooded animals  stimulates  the  nerve-centres,  acting 
most  plainly  upon  the  higher  psycho-motor  cells  of  the 
brain,  then  upon  the  medulla  oblongata  and  the  cord. 
It  seems  especially  to  affect  the  action  of  the  semicircu- 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


519 


lar  canals,  causing  vertigo,  and  in  dogs,  at  least,  disturb- 
ances of  equilibrium  and  rolling  movements.  The  pupil 
is  dilated.  A  lengthening  in  the  time  of  muscular  con- 
traction, claimed  to  exist  by  Ott,  Buchheim,  and  others, 
is  denied  by  Nikolsky  and  Anrep.  Respiration  is  has- 
tened and  labored  in  warm-blooded  animals;  in  fatal 
doses  the  breathing  stops  before  the  heart-action.  Upon 
the  heart  moderate  doses  of  cocaine  in  warm-blooded 
animals  lessen  the  inhibitory  action  of  the  vagus  and 
increase  the  rapidity  of  the  beat  without  impairing  its 
strength.  Moderate  doses  appear  also  to  raise  arterial 
pressure,  but  in  medicinal  doses  the  cocaine  does  not 
greatly  affect  the  vaso-motor  system.  Moderate  doses 
increase  intestinal  peristalsis,  while  large  doses  lessen  it 
and  seem  to  produce  a  venous  congestion  of  the  walls. 

There  is  a  decrease  in  the  secretion  of  saliva  and  of 
mucus,  while  the  urine  does  not  seem  to  be  much  affected, 
except  in  toxic  doses. 

So  far  as  the  local  anaesthetic  effect  of  cocaine  is  con- 
cerned, it  seems  to  have  been  independently  noticed  by 
several  persons,  as  we  have  indicated  above.  The  prac- 
tical (application  of  this  knowledge,  however,  is  only  of 
very  recent  date. 

THE  TENEMENT-HOUSE  CIGAR    BILL  AND  THE   FAC- 
TORY NUISANCE. 

There  have  been  two  recent  decisions  on  health  ques' 
tions  which  deserve  attention.  The  first  of  these  is  the 
judgment  of  the  General  Term  of  the  New  York  Supreme 
Court,  holding  that  the  Tenement-house  Cigar  bill  is 
unconstitutional.  This  law  was  passed  at  the  last  session 
of  the  Legislature  and  took  effect  immediately.  By  its 
provisions  it  prohibited  the  manufacture  of  cigars  in  all 
tenement-houses  occupied  as  the  home  or  residence  of 
more  than  three  families  living  independently  of  one  an- 
other and  doing  their  cooking  on  the  premises.  Two 
days  after  the  passage  of  the  act,  Peter  J ,  who  occu- 
pied seven  rooms  on  the  first  floor  of  a  tenement-house 
and  manufactured  cigars  in  one  of  them,  was  arrested  for 
breaking  the  law.  He  was  unable  to  procure  bail  and 
was  committed  to  prison.  A  writ  of  habeas  corpus  was 
then  sued  out  in  his  behalf,  but  was  dismissed,  and  an 
appeal  from  this  decision  has  been  up  for  review  at  the 
General  Term  of  the  Supreme  Court,  where  it  was  reversed 
and  the  law  declared  unconstitutional.  The  grounds  for 
this  decision  are  that  the  labor  of  the  poor  man  is  his 
only  property  and  as  much  entitled  to  protection  as  any 
of  its  accumulations ;  that  this  law  suddenly  deprived  him 
of  the  free  use  of  this  labor,  and  in  effect  seized  private 
property  without  just  compensation.  Such  a  result  is 
against  the  Constitution  of  the  State,  and  any  law  which 
allows  it  must  be  unconstitutional.  The  opinion  goes  on 
further  to  say  that  the  ostensible  object  of  the  bill,  viz., 
to  secure  better  health,  as  declared  in  the  title  of  the  bill,  is 
a  mere  pretence,  and  that  the  real  object  is  to  "  suppress 
and  restrain  such  manufacture  in  the  cases  covered  by  the 
act,  for  the  purpose  of  preventing  successful  competition, 
injurious  to  other  modes  of  manufacturing  the  same  article.'* 
The  judges  find  reasons  for  this  belief  in  the  very 
&ce  of  the  bill,  and  they  certainly  make  out  a  strong 
case.  They  say  that  tenement-houses  where  the  cooking 
is  not  done  on  the  premises  are  exempted,  and  that  the 
most  thronged  and  over-crowded  tenements,  which   are 


occupied  largely  by  persons  who  live  from  hand  to  mouth 
and  by  beggary,  can  manufacture  cigars  without  interfer- 
ence. Also  the  first  floor  of  the  tenement-house  is  ex- 
cepted if  in  addition  to  the  manufacture  of  cigars  there 
be  a  store  for  their  sale,  while  if  health  were  the  object 
this  floor,  being  the  resort  of  more  persons  than  the  othersr 
would  certainly  be  under  the  provisions  of  the  bill.  The 
law  fails  to  secure  health  to  any  reasonable  extent,  but 
in  the  words  of  the  judges  it  accomplishes  a  very  differ- 
ent thing :  "  If  the  act  were  general  and  aimed  at  all 
tenement-houses,  and  prohibited  for  sanitary  reasons  the 
manufacture  of  cigars  and  tobacco  in  all  such  buildings, 
or  if  it  prohibited  such  manufacture  in  the  living-rooms  of 
all  tenants,  another  case  would  be  presented.  But  in  the 
form  in  which  it  comes  before  us  it  is  so  unjust  in  its  ine- 
qualities, so  harsh  and  oppressive  upon  the  labor  of 
poverty,  so  keenly  discriminative  in  favor  of  the  stronger 
classes  engaged  in  the  same  occupation,  that  it  certainly 
ought  not  to  have  been  enacted." 

It  is  said  that  the  large  manufacturers  were  confidently 
expecting  that  the  constitutionality  of  the  bill  would  be 
upheld,  and  have  been  perfecting  machines  which  would 
do  away  very  largely  with  hand  labor.  If  these  machines 
should  really  be  set  at  work  the  result  will  be  deplorable, 
as  the  workmen  would  be  in  the  position  of  having  the 
opportunity  for  work  given  them  again  but  the  work  all 
taken  away  from  them.  The  decision  of  the  General 
Term  may  be  appealed  from,  and  if  so  the  matter  cannot 
be  considered  as  settled. 

The  second  case  referred  to  was  one  in  the  New 
Jersey  Court  of  Chancery,  where  an  application  was 
made  by  the  Board  of  Health  of  Lambertville  for  an  in* 
junction  preventing  the  proprietor  of  a  tomato-canning 
establishment  from  turning  the  refuse  firom  his  works  into 
a  creek,  it  being  alleged  that  the  odor  of  the  decaying  vege-' 
table  matter  was  injurious  to  the  public  health.  The 
case  was  bitterly  contested,  and,  as  is  usual  in  such  cases^ 
the  expert  evidence  presented  was,  much  of  it,  absolutely 
contradictory.  It  was  claimed  on  behalf  of  the  defendant 
that  the  smells  were  not  harmful,  and  also  that  others 
were  responsible  for  the  unhealthy  condition  of  the  town« 
The  Vice-Chancellor,  in  deciding  the  case,  held  that  the 
defendant's  factory  was  the  primary  source  of  the  nuisance, 
and  that  this  made  him  responsible,  even  though  the  bad 
condition  of  the  sewer  and  the  discharges  of  filth  by  other 
persons  might  have  contributed  to  the  nuisance ;  and  a 
decree  was  made  forbidding  any  further  deposit  of  the 
decaying  vegetable  matter. 

There  are  a  number  of  similar  cases  depending  upon 
this  decision,  which  is  an  important  one  as  tending  to 
strengthen  the  powers  of  boards  of  health. 


ACUTE  PAINFUL  PARAPLEGIA. 

Under  the  name  of  ''acute  painful  paraplegia"  M« 
Dumolard  describes  an  affection  which  closely  simulates 
an  attack  of  rheumatism.  The  pains  suffered  by  the 
patients  are  often  intolerable,  and  the  paralytic  symp- 
toms, which  they  rarely  mention,  may  pass  unperceived^ 
The  affection  is  then  characterized  by  the  following 
phenomena :  paralytic  symptoms  feebly  manifested,  but 
with  very  intense  pains ;  on  this  account  Dumolard  calls 
it  ''  acute  painful  paraplegia.'' 


520 


THE   MEDICAL  RECORD.     •  [November  8,  1884. 


This  designation,  however,  is  insufficient,  as  it  says 
nothing  of  the  seat  and  nature  of  the  malady.  It  is 
pharacterized,  at  the  beginning,  by  sharp  pains  in  the 
regions  of  the  kidneys  and  in  the  lower  limbs,  soon  fol- 
lowed by  incomplete  paralysis  of  the  abdominal  members 
and  of  the  bladder,  with  hyperexcitation  of  the  reflex  acts 
of  the  lumbar  portion  of  the  cord.  In  some  cases  the 
pains  leave  the  lower  limbs  and  attack  the  upper  part  of 
the  trunk  and  the  upper  limbs,  thus  causing  a  very  pain- 
ful though  incomplete  cervical  paralysis.  Though  last- 
ing for  a  considerable  time,  the  affection  seems  to  tend 
always  toward  a  cure  ;  but  its  course  is  not  always  simple 
and  regular. 

As  the  disease  is  somewhat  rare,  and  as  nothing  is 
known  of  its  nature  or  anatomical  situation  of  the  patho- 
logical disturbances  caused  by  it,  it  may  be  interesting 
to  give  a  short  rSsumS  of  the  symptoms  presented  in  the 
cases  reported  by  Dr.  Dumolard.  The  affection  com- 
mences, as  has  already  been  stated,  with  acute  pains  in 
the  kidneys  and  lower  limbs.  Both  limbs  are  affected, 
and  the  pains  extend  to  the  feet.  At  times  they  are 
very  severe,  and  are  accompanied  by  muscular  contrac- 
tions and  cramps  of  the  thighs  and  legs.  They  some* 
times  come  on  without  appreciable  cause,  while  at  other 
times  they  are  produced  by  attempts  at  movement,  by  a 
shock,  or  even  by  a  slight  touch.  The  reflex  power  of 
the  cord  is  evidently  in  a  state  of  hyperexcitation.  The 
patients  seem  to  be  fully  aware  that  the  pains  are  not 
the  sole  cause  of  the  loss  of  the  power  of  motion.  The 
pains  gradually  increase,  extend  to  the  bladder,  and 
micturition  becomes  painful.  These  cases  were  at  first 
diagnosticated  by  Dumolard  as  rheumatism,  for  which  he 
prescribed  salicylate  of  soda,  with  the  view  that  the 
meninges  were  affected,  but  without  result.  In  a  vari- 
able time,  three  to  six  weeks,  the  condition  begins  to  im- 
prove, and  the  affection  seems  to  pass  off  spontaneously. 
In  other  cases  the  pains  begin  in  the  shoulder  and  extend 
to  the  wrist.  In  these  cases  the  bladder  may  not  be 
affected. 

We  have  now  briefly  analyzed  the  principal  symptoms 
of  this  curious  affection.  It  commences  with  a  lumbar 
pain,  with  a  sensation  of  weight  in,  and  radiation  into,  the 
back.  It  may  be  at  first  very  acute  and  then  gradually 
diminish  in  intensity ;  at  other  times  it  is  slight  in  the 
beginning,  and  becomes  more  and  more  violent.  It  first 
commences  just  below  the  kidneys,  then  attacks  the 
dorsal  region  and  ascends  toward  the  neck.  The  pains 
in  the  legs  do  not  always  follow  the  course  of  the  sciatic 
nerve,  nor  are  they  localized  in  the  joints,  as  in  articular 
rheumatism,  but  are  seated,  as  a  rule,  along  the  entire 
surface  of  the  affected  limb.  Whatever  may  be  the  man- 
ner in  which  the  affection  commences,  the  patient  soon 
becomes  completely  paralyzed  in  the  painful  regions, 
while  the  pains  still  continue.  The  reflex  power  of  the 
cord  is  then  slightly  exaggerated,  and  the  least  shock  to 
the  feet,  or  the  least  movement  of  the  affected  parts,  is 
sufficient  to  cause  the  painful  tetanic  contractions.  Is  it 
not  possible  that  this  exaltation  of  spinal  reflex  may  ex- 
plain, in  certain  cases,  the  sort  of  muscular  impotence 
which  prevents  movements  on  the  part  of  the  patient, 
rendering  him  incapable  of  taking  a  step,  while  in  the 
horizontal  position  their  muscles  appear  to  be  very 
strong  ?     Will  not  this  also  explain  the  difficulty  of  mic- 


turition, by  supposing  that  the  exaggeration  of  the  re- 
flexes causes  a  contraction  of  the  neck  of  the  bladder  ? 

The  general  state  in  this  affection  is  never  grave ;  the 
pulse  rarely  goes  above  80 ;  the  skin  is  moist ;  the  tongue, 
though  white,  remains  moist,  and  the  general  aspect  of 
the  patient  is  indicative  only  of  pain.  The  bladder  is 
generally  affected,  and  the  patient  makes  futile  attempts 
to  completely  evacuate  it.  The  paralysis  of  the  bladder 
and  limbs  is  never  complete,  however.  As  a  rule,  the 
pains  are  confined  to  the  region  of  the  kidneys  and  to 
the  lower  limbs  during  the  whole  time ;  they  may,  how- 
ever,  as  stated  before,  suddenly  leave  these  regions  and 
attack  the  arms  and  upper  part  of  the  body,  and  give 
rise  to  symptoms  of  painful  and  incomplete  paralysis  of 
the  cervical  region.  The  pains  do  not  follow  the  nerve- 
trunks,  nor  are  they  localized  in  the  vicinity  of  the 
trunks ;  the  entire  surface  of  the  limb  is  affected.  Nor 
are  there  any  lancinating  pains,  such  as  are  seen  in  cases 
of  neuralgia. 

The  cause  of  the  affection  is  obscure.  All  of  the  pa- 
tients seen  by  Dumolard  were  in  middle  life  and  of  the 
working  class.  Most  of  them  referred  their  attack  to  ex- 
posure to  cold  or  wet.  It  is  noticeable  that  in  six  cases 
out  of  seven  the  patients  were  attacked  in  February  or 
March.  Furthermore,  all  of  the  patients  were  males. 
The  treatment  is  necessarily  symptomatic ;  energetic  re- 
vulsants  over  the  region  of  the  cord  should  be  used  per- 
severingly;  the  saline  purgatives  are  indicated  for  the 
saburral  state  of  the  digestive  tract ;  bromide  of  potas- 
sium, as  a  moderator  of  the  spinal  reflexes,  is  also  indi- 
cated. Chloral  and  morphine  are  indispensable  for  re- 
ducing the  hyperaesthesia  of  the  limbs  and  for  the 
insomnia.  It  would  seem  that  the  electric  current  would 
be  useful  in  the  paralyzed  condition  of  the  limbs. 

An  affection  almost  precisely  similar  to  this  in  every 
respect  was  described  by  Bockhammer  some  years  ago, 
and  an  analysis  of  his  paper  may  be  found  in  the  Revue 
des  Sciences  M^dicdles^  vol.  viii.,  p.  183.  It  appeared 
as  an  epidemic  in  Spain  under  the  name  of  the  Azannon 
disease,  from  the  village  where  it  appeared  for  the  first 
time.  The  description  of  it  given  by  Bockhammer  cor- 
responds in  almost  every  detail  with  that  of  Dumolard. 

Can  it  be  that  this  is  an  abnormally  mild  form  of  spinal 
meningitis  ?  Or  may  it  not  be  due  to  lead-poison  ?  It  is 
scarcely  probable  that  it  is  a  manifestation  of  syphilis. 
Certainly  its  etiology  is  very  obscure,  nor  is  it  likely  to  be 
cleared  up,  seeing  that  the  patients  all  recover. 


THE  NEW  PENAL  CODE  AND  THE  RHINELANDER  CASE. 

In  our  issue  of  September  20th  we  gave  the  main  facts 
regarding  the  Rhinelander  case,  which  for  many  reasons 
has  excited  unusual  interest  in  the  community.  The  de- 
fendant, Mr.  William  C.  Rhinelander,  committed  a  homi« 
cidal  assault  upon  Mr.  John  Drake,  whom  he  believed 
to  be  alienating  the  affections  of  his  (Rhinelander^s) 
wife.  Being  brought  to  trial,  the  prisoner's  relations 
claimed  that  he  was  insane,  while  he  himself  denied  this 
and  contended  that  he  should  be  brought  to^  criminal 
trial  for  his  act. 

The  position  thus  taken  by  the  prisoner  was  unique. 
But  besides  this,  the  trial  involved  the  application  for  the 
first  time  of  the  sections  in  the  new  Code  providing  for 


November  8,  1884.^ 


THE  MEDICAL  RECORD. 


521 


the  trial  of  persons  who  put  in  a  plea  of  insanity  as  an 
excuse  for  crime.  The  law  says  that  if  any  person  under 
indictment  for  the  crime  of  murder  or  attempt  at  mur- 
der shall  appear  to  be  insane,  the  Court  of  Oyer  and 
Terminer  may,  with  the  concurrence  of  the  presiding 
judge,  inquire  into  the  sanity  of  such  person,  and  may 
for  that  purpose  appoint  a  commission  to  inquire  into 
the  facts  of  the  case  and  report  to  the  court.  Such  a 
commission  was  appointed  by  Recorder  Smyth,  which, 
consisted  of  Dr.  William  Detmold,  Mr.  Patrick  Nolan,  and 
Mr.  Edward  Paterson.  A  large  an>ount  of  evidence  was 
taken.  A  report  was  finally  made  to  the  Court,  in  which 
two  of  the  commissioners,  Dr.  Detmold  and  Mr.  Nolan, 
stated  the  opinion  that  the  prisoner  was  insane,  while 
Mr.  Paterson  gave  a  contrary  opinion. 

Recorder  Smyth  has  recently,  after  reviewing  the  evi- 
dence furnished  by  the  commission,  reversed  its  deci- 
sion and  decided  that  the  defendant  is  sane.  In  doing 
this  he  establishes  the  precedent  that  a  judge  may  reverse 
the  decision  of  the  commission  he  appoints.  The  case, 
besides  furnishing  a  precedent  on  the  above  point,  is  in- 
structive in  that  it  shows  how  valueless  expert  testimony 
may  still  be,  even  under  the  new  law.  This  law,  in  fact* 
though  it  gives  some  additional  guarantee  that  the  sanity 
of  a  prisoner  is  submitted  to  a  careful  test,  does  not  in 
the  least  improve  upon  the  mode  of  getting  expert 
opinion.  In  the  present  case  the  weight  of  scientific 
opinion  was  almost  entirely  on  the  side  of  Rhinelander's 
insanity.  In  fact,  we  do  not  recall  a  single  name  among 
the  experts  put  up  by  Rhinelander's  counsel  which  would 
carry  weight  in  the  profession.  As  long  as  lawyers  can 
set  up  any  doctor,  however  unqualified  as  an  expert,  we 
must  expect  the  present  state  of  affairs  to  continue.  It 
is  as  ridiculous  to  assume  that  every  medical  man,  even 
if  he  has  had  a  little  special  experience,  is  an  expert  on 
insanity  as  to  suppose  that  every  general  practitioner  is 
an  ophthalmologist  or  a  dermatologist. 


DEAD  TEETH  IN  THE  JAWS. 

It  would  be  well  if  the  dead  (pulpless)  teeth  filled  and 
left  in  the  jaws  of  people  were  labelled  "  at  the  owner's 
risk,"  and  all  golden  "  crowns  "  and  "  bridge  "  structures 
attached  to  dead  teeth  marked  "  extra  hazardous ; "  for  it 
appears  that  when  the  pulp  of  a  tooth  has  been  removed 
life  no  longer  exists  in  the  dentine,  which  derives  its 
nourishment  from  the  pulp,  and  there  is  no  way  of  pre- 
venting the  dead  matter  left  in  its  canaliculi  from  under- 
going decay  for  an  indefinite  period  of  time.  This  matter 
has  been  touched  on  by  our  correspondent  in  another 
column,  and  we  believe  that  the  attention  of  the  general 
practitioner  is  now  being  directed  to  this  subject  more 
than  heretofore.  It  would  seem  that  dentistry  has  per- 
haps been  over-zealous  in  its  efforts  to  retain  defective 
teeth  in  the  mouth,  or  to  supplant  them  with  apparatus 
which  often  proves  to  be  anything  else  than  harmless  to 
the  patient.  In  carrying  both  of  these  branches  of  den- 
tistry to  what  the  medical  mind  regards  as  a  dangerous 
extrem**,  the  health  of  the  patient  has  too  often  been 
lost  sight  o£  This,  after  all,  naturally  enough,  was  to  be 
expected  so  long  as  medical  men  relegated  the  manage- 
ment of  nearly  all  diseases  of  the  mouth,  such  as  the  re- 
moval of  dead  teeth,  the  treatment  of  alveolar*  abscesses, 


diseases  of  the  antrum  of  Highraore,  and  facial  neuralgias, 
to  dentists  who  possessed  very  little  if  any  knowledge  of 
medicine.  It  is  in  consequence  of  this  course  that  the 
treatment  of  jaw  diseases  has  been  lost  sight  of  by  the 
general  surgeon,  and  we  fear  that  the  well-intended 
efforts  of  dental  schools  to  impart  surgical  knowledge  to 
the  mere  mechanics  who  constitute  by  far  the  greater 
number  of  their  students,  will  not  remedy  this  neglected 
feature  in  medical  education. 

Dentists  having  a  predilection  for  surgery  of  the  jaws 
would  do  well  to  recognize  this '  state  of  things,  and  to 
bear  in  mind  that  a  medical  education  and  training  are 
necessary  accomplishments  to  acquire  before  the  study 
and  treatment  of  any  region  of  the  body  may  be  success- 
fully taken  up.  In  this  way  only  may  the  aspirant  es- 
tablish himself  in  any  medical  specialty,  so  as  to  gain 
the  confidence  of  the  profession.  At  the  present  time  it 
is  believed  that  not  over  five  per  cent,  of  dental  gradu- 
ates, not  to  mention  others  who  practise  dentistry,  have 
taken  the '  degree  [of  M.D.,  and  of  these  a  very  small 
number  have  had  any  training  in  the  practice  of  medi- 
cine. 

The  practitioner,  in  the  meantime,  who  neglects  to  in- 
quire into  the  state  of  his  patient's  teeth,  may  encounter 
much  difficulty  in  overcoming  diseases,  especially  those 
about  the  head,  which  can  in  any  way  be  affected  by 
reflex  nervous  influences  from  this  source ;  and  when 
the  question  of  the  removal  of  a  dead  tooth  which  gives 
rise  to  disturbance  is  considered,  it  should  not  be  forgot- 
ten that  local  pain  may  be  entirely  unobserved  by  the 
patient. 


l^eMJB  0f  ttije  ^atjejek 


Dr.  David  B.  Miller,  of  this  city,  died  on  November 
I  St,  of  Bright's  disease.  He  was  born  in  1836,  and  grad- 
uated at  the  College  of  Physicians  and  Surgeons  in  1858. 

Dr.  Paul  Grawitz,  of  Berlin,  assistant  at  the  Patho- 
logical Institute,  under  Virchow,  has  been  appointed  to 
the  charge  of  the  Carnegie  Laboratory,  Bellevue  Hospital 
Medical  College.  Dr.  Grawitz  has  made  a  number  of 
very  scientific  pathological  researches,  and  is  eminently 
qualified  by  training  to  fill  successfully  the  position  to 
which  he  is  chosen.  The  faculty  of  the  college  are  show- 
ing  a  desire  to  make  the  Carnegie  Laboratory  an  institu- 
tion of  positive  practical  and  scientific  value  not  only  to 
their  students  but  to  the  profession  of  the  city. 

Our  Medical  Centenarian. — Harper's  Weekly  pub- 
lishes an  excellent  portrait  of  Dr.  Christopher  Columbus 
Graham,  of  Louisville,  Kentucky,  who  recently  arrived 
at  the  age  of  one  hundred  years.  His  fellow-citizens 
celebrated  the  occasion  by  tendering  him  a  banquet. 

A  Doctor's  Heroism. — Under  this  title  the  London 
Spectator  gives  an  account  of  a  Dr.  Samuel  Rabbeth,  of 
London,  who  sucked  the  diphtheritic  membrane  out  of  a 
trachea  tube  to  prevent  the  suffocation  of  his  patient. 
He  caught  the  diphtheria  himself  and  died. 

Another  French  Cholera  Commission. — Professor 
Jules  Aronssqhn  has  been  appointed  by  the  French 
Government  as  head  of  the  commission  to  study  the 
cholera  in  Italy. 


522 


THE   MEDICAL  RECORD. 


[November  8,  1884. 


The  Latest  Estimate  of  the  Deaths  from 
Cholera  is  as  follows :  France,  6,741 ;  Corsica  (esti- 
mated), 100;  Algiers  (estimated),  200;  Italy,  12,283; 
Spain,  436.  Grand  total,  19,760.  The  above  repre- 
sents a  period  of  from  June  14,  1884,  when  the  first 
case  occurred  at  Toulon,  to  October  15th.  There  were 
probably  about  50,000  cases  of  the  disease. 

Bequest  to  Indigent  Medical  Students. — The 
late  Countess  Bose,  of  Kassel,  has  left  to  the  University 
of  Berlin,  780,000  marks  as  a  fund  for  the  use  of  indigent 
medical  students. 

Professor  Du  Bois  Reymond  Challenged  by  a 
Quack. — Ex  gratia  Bismarck,  Professor  Schweininger 
has  challenged  Professor  Du  Bois  Reymond  to  fight  a 
duel,  Schweininger  having  taken  offence  at  the  remarks 
of  Reymond  on  his  appointment  to  a  chair  in  Berlin 
University.     Professor  Reymond  declines  to  fight. 

Two  Decisions  Regarding  the  Pay  of  Expert 
Witnesses. — Judge  White,  of  Pennsylvania,  has  decided 
that  under  the  law  a  physician  must  answer  a  summons 
from  a  court  to  appear  and  testify  as  an  expert  without 
remuneration. 

A  directly  contrary  opinion  to  Judge  White's  was  re- 
cently delivered  in  the  Circuit  Court  of  Chicago.  A  dis- 
pensary patient  sued  Dr.  Hotz  and  his  substitute.  Dr. 
Lee,  for  the  loss  of  an  eye,  claiming  $10,000.  Another 
physician  was  summoned  to  testify  as  to  facts  in  the 
case.  Being  then  asked  to  testify  as  an  expert  and  give 
an  opinion,  he  refused. 

"This  action  of  the  court,"  says  the  Weekly  Review  ^  **is 
of  considerable  importance,  as  it  shows  that  a  physician 
cannot  be  made  liable  for  any  act  of  his  locum  tenens 
when  duly  qualified  by  law,  and  further  that  no  physician 
is  obliged  when  subpoenaed  as  a  witness  of  fact  to  ex- 
press an  opinion  as  an  expert." 

The  Oldest  Living  Microcephalic — ^At  a  recent 
sitting  of  the  Berlin  Medical  Society,  Professor  Virchow  ex- 
hibited a  girl,  aged  fourteen,  with  a  slight  though  normally 
developed  figure,  but  with  a  diminutive  head,  scarcely  as 
large  as  a  man's  fist.  She  came  from  Offenbach,  and 
was  introduced  by  her  mother,  a  tall,  large-boned  woman. 
Her  face  is  not  larger  than  that  of  a  new-born  child,  with 
a  sharply  projecting  nose  and  prominent  jaws  ;  her  com- 
plexion is  delicate,  and  her  features  resemble  those  of  a 
bird  of  prey.  The  size  of  the  brain  in  this  diminutive 
skull  is  proportionately  small,  and  the  intellectual  powers 
are  not  developed  beyond  those  of  a  six-months  child. 
The  only  word,  besides  some  inarticulate  sounds,  that 
the  girl  can  pronounce  is  mamma.  The  parents  had 
had  seven  children,  of  whom  four  were  microcephalic, 
but  only  the  one  exhibited  had  lived.  When  she  was  at 
home  she  sat  quietly,  and  preferred  avoiding  the  society 
of  other  children,  generally  withdrawing  into  a  corner  of 
the  room.  She  ate  and  drank  purely  mechanically, 
Virchow  referred  to  this  case  as  the  oldest  one  living. 
At  the  recent  meeting  of  the  French  Association  for  the 
Advancement  of  Science,  Dr.  Magitot  reported*  the  case 
of  a  microcephalic  woman,  aged  thirty,  weight  seventy 
pounds.  She  showed  more  intelligence  than  Virchow*s 
case,  and  could  dress,  take  care  of  herself,  and  speak 
several  words. 


The  Board  of  Health  of  this  city  receives  this  year 
an  appropriation  of  $420,282.     It  wanted  $17,000  more. 

American  Use  of  the  Thermometer  in  Disease  in 
1 808.— In  Dr.  Elisha  North's  "Treatise  on  Malignant 
Epidemic  Spotted  Fever,  or  Cerebrospinal  Fever,"  he 
tells  us,  page  41,  that  it  will  always  be  well  to  ascertain 
the  degree  of  the  patient's  heat  by  a  thermometer. 

Medical  Department  University  of  Vermont.— 
Dr.  W.  Oliver  Moore  has  been  appointed  Professor  of 
Diseases  of  Eye  and^Ear,  in  place  of  Dr.  D.  B.  St.  John 
Roosa,  who  has  resigned,  and  Dr.  Stephen  S.  Burt  has 
accepted  the  chair  of  Professor  of  Physical  Diagnosis. 

Pacini's  "  Cholera  Germ." — It  has  been  stated  that 
Professor  Pacini,  of  Naples,  announced  the  discovery  of 
a  cholera-microbe  as  early  as  1855.  A  claim  of  priority 
over  Koch  has  been  put  in,  to  which,  however,  we  at  the 
time  denied  validity.  Dr.  A.  Bianchi,  of  Florence,  has 
just  collected  and  published  Pacini's  works  upon  this 
subject,  from  which  it  appears,  as  we  anticipated,  that 
the  particular  microbe  found  by  the  Italian  professor 
differs  entirely  from  that  of  Koch.  It  is  a  vibrio  found 
in  the  intestine,  and  which  by  its  growth  produces  irritar 
tion. 

M.  RicoRD  ON  the  Cholera. — At  a  recent  meeting 
of  the  Paris  Acad6mie  de  M6decine  the  venerable  Ricord 
made  some  remarks  upon  the  cholera.  He  believed  that 
it  was  not  contagious,  and  that  it  originated  de  novOj  and 
was  not  always  imported.  Ricord' s  experience  was  dur- 
ing the  epidemic  of  1832.  His  views  are  in  accord  with 
those  of  Jules  Gu^rin. 

Statistics  of  Cholera  in  Italy. — Considering  the 
brevity  of  its  duration,  according  to  La  Gazzetta  degli 
Ospitali  {Lancei)y  the  present  epidemic  of  cholera  in 
Naples  has  exceeded  in  severity  all  previous  invasions, 
including  the  terrible  one  of  1837.  That  was  the  cause 
of  13,800  deaths  in  five  months.  The  first  death  from 
cholera  in  Naples  this  year  occurred  on  August  21st. 
From  that  day  to  midnight,  September  30th,  I  the 
cases  numbered  10,957,  and  5,778  deaths.  In  the  hos- 
pitals the  recoveries  were  1,121,  the  deaths  787.  The 
actual  population  of  Naples  is  500,000.  At  Torre  An- 
nunziata  137  deaths  occurred  in  234  cases.  From  the 
I  St  to  the  30th  of  September  294  soldiers  of  the  Naples 
garrison  were  attacked  with  cholera,  134  of  them  fatally. 
The  mean  mortality  was  42  per  cent.  In  the  aristocratic 
quarter  of  Chiaja,  during  the  whole  of  September,  162 
deaths  occurred  among  252  cases  of  cholera.  Byfar 
the  greatest  number  of  victims  were  women. 

Death  from  Cholera  of  a  Distinguished  Italian 
Physician. — We  chronicle  with  regret  the  news  of  the 
death  of  Professor  Luigi  Somma,  of  Naples,  the  founder 
and  director  of  the  recently  established  periodical  de- 
voted to  the  study  of  diseases  of  children,  and  entitled 
Archivio  di  Patologia  Infantile,  A  victim  to  cholera, 
the  scourge  which  has  so  devastated  the  beautiful  city  in 
which  he  lived  and  labored,  he  fell  at  the  post  of  duty 
and  of  honor,  on  September  19th  last. 

Another  Doctor's  Novel. — A  well-known  London 
physician  has  just  published  a  novel  called  '*  Gaythome 
HalL"     It  4s  well  spoken  of.    , 


November  8,  1884.] 


THE   MEDICAL  RECORD. 


523 


Klein's  **  Bacillus  Dinner.'* — ^The  report  that  Dr. 
E.  Klein  swallowed  a  dose  of  cholera  bacilli  is  laughed 
at  in  Berlin  circles  among  the  supporters  of  Koch.  It 
yras  a  sensational  performance,  they  assert,  and  proves 
nothing,  except  that  a  suitable  nidus  is  necessary  for  the 
bacilli  to  develop  in — which  Klein  did  not  have. 

Dr.  James  C.  Carson  of  the  Institution  for  the 
Deaf  and  Dumb  in  this  city  has,  says  the  New  York 
Medical  Journal^  been  appointed  Superintendent  of  the 
State  Idiot  Asylum  at  Syracuse. 

Two  Faculties  and  One  College. — The  style  of 
two  medical  colleges  and  one  faculty  is  not  new,  and 
used  to  be  served  up  at  Louisville,  Ky.,  with  consider- 
able financial  success.  To  have  two  faculties  and  one 
college,  however,  is  rather  novel.  Says  the  Maryland 
Medicaf  Journal:  "The  dissensions  between  the  two 
factions  claiming  to  be  the  Baltimore  Medical  College 
have  been  freely  ventilated  by  the  secular  press  of  this 
city.  The  state  of  the  controversy  has  not  changed, 
and  the  claims  to  the  right  of  title  and  property  of  the 
college  will  have  to  be  decided  by  the  courts.  Two 
Faculties,  having  separate  buildings,  are  instructing  stu- 
dents under  the  charter  of  the  Baltimore  Medical  Col- 
lege. This  is  a  unique  controversy,  and  its  results  will 
be  watched  with  interest.  So  far  as  we  can  judge,  the 
Monroe  faction  seems  to  have  the  advantage  up  to  the 
present  time." 

The  Charity  Organization  Society  and  the 
Medical  Charities. — The  Second  Annual  Report  of 
the  New  York  Charity  Organization  Society  states  that 
it  now  has  one  hundred  and  eighty-three  charitable 
societies  co-operating  with  it.  Among  these  there  are 
only  seven  medical  charities,  viz.:  Home  for  Convales- 
cents, House  of  Rest  for  Consumptives^  New  York 
Hospital,  New  York  Infirmary  for  Women  and  Children, 
Northern  Dispensary,  Woman's  Hospital,  Columbian 
Institute.  It  is  evident  that  as  yet  there  is  very  little 
medical  *^  charity  organization  "  despite  all  that  has  been 
said. 

The  Courage  of  Physicians. — The  British  Medical 
Journal^  under  date  of  September  1 7th,  states  that  three 
professors  and  five  physicians  had  been  attacked  with 
cholera  during  the  discharge  of  their  duties  at  Naples. 

The  Medical  and  Surgical  Reporter  gives  currency  to  a 
statement  that  a  young  Pole,  living  in  Warsaw,  has  offered 
himself  in  the  interest  of  science  to  be  experimented 
upon  in  reference  to  the  cholera.  '^  I  am  unmarried,'* 
he  says,  "  I  have  no  ties  of  any  kind,  and  no  plans  for  the 
future."     His  offer  had  better  be  taken. 

The  Peculiar  Progress  of  the  Italian  Cholera 
Epidemic. — A  Lancet ^  correspondent  writes  that*  there 
are  certain  phenomena  peculiar  to  this  outbreak  of 
cholera  in  Southern  Europe  which  should  form  the 
theme  of  careful  official  inquiry.  After  the  outburst  of 
the  malady  in  Toulon  its  direction  was  much  less  north- 
ward than  southward.  Again,  both  in  Italy  and  France 
it  visited  great  seaports  most  heavily,  while  in  Italy  this 
curious  spectacle  was  witnessed — it  selected  alternate 
seaports  for  attack.  For  example,  it  overleaped  the 
populous  and  not  over-cleanly  Genoa,  and  alighted 
heavily  on  the  less  populous  and  not  more  insanitary 


Spezia.  Again,  it  overleaped  the  less  populous  and  de- 
cidedly insanitary  Leghorn,  and  exploded  with  fearful 
violence  in  the  more  populous,  though  not  very  much 
more  insanitary,  Naples.  What  was  its  principle  of  se- 
lection ?  How  is  it  that  Messina  and  Palermo,  sea- 
ports so  severely  scourged  by  it  in  former  visitations,  es- 
caped so  cheaply  on  this  occasion  ?  And  how  is  it  that 
the  great  provincial  capitals — Turin,  Milan,  Venice, 
Florence,  and  Rome  herself,  all  of  them  the  scenes  of 
virulent  outbreaks  on  previous  occasions — ^have  hardly 
had  one  case  ? 

Cholera  and  Cleanliness  in  Naples. — A  corre- 
spondent of  The  Lancet  writes  that  the  mode  in  which 
the  cholera  attacked  the  people  of  Naples  has  been  very 
perplexing  to  the  hygienists.  For  example,  the  narrow, 
ill-ventilated  streets  intersecting  blocks  of  buildings  in 
which  the  population  teems  like  rabbits  have  been  pre- 
cisely those  in  which  cholera  has  numbered  least  victims ; 
while  the  dwellings  which,  from  their  amplitude  and  sit- 
uation, the  freely  aired  thoroughfares  dividing  them,  are 
in  marked  contrast  to  the  preceding,  have  contributed 
the  heaviest  contingent  to  the  hospital  and  the  cemetery. 
Again,  the  ill-fed,  badly  clothed,  unwashed  inmates  of 
the  rookeries  have  come  off  very  lightly  in  comparison 
with  the  well-dieted,  comfortably  clothed,  not  uncleanly 
bourgeoisie.  "  Partly  because  by  nature,"  says  the  cor- 
respondent of  the  Opinione^  whose  letters  from  Naples 
have  given  the  best  account  of  the  epidemic,  "  we  have 
something  of  the  Arab,  partly  because  the  facts  above 
stated  reinforce  the  sentiment  of  fatalism  which  is  at  the 
bottom  of  our  southern  character,  our  populace  laughs 
to  scorn  all  the  admonitions  of  the  authorities  and  devours 
figs,  capsicums,  tomatoes,  more  or  less  unripe,  does 
everything  in  fact  which  it  has  means  to  indulge  in, 
though  forbidden  by  the  profession.  As  to  soup-kitch- 
ens, it  will  have  none  of  them.  *  They,*  it  says,  *  are  for 
the  sick,  and  we  are  quite  well.*"  All  this,  however, 
should  not  shake  our  faith  in  the  efficacy  of  pure  water  and 
cleanly  dwellings. 

A  Floating  Hospital. — Chicago  has  followed  the 
example  of  New  York,  and  last  summer  established  a 
floating  hospital,  upon  which  twenty-one  thousand  four 
hundred  and  eighty-nine  persons  were  cared  for  and 
treated. 

A  Nov^L  Introductory. — The  custom  of  giving 
formal  introductory  addresses  is  growing  less  popular  in 
England,  owing,  it  is  said,  to  the  too  boisterous  way  in 
which  they  are  received  by  the  students.  The  opening 
ceremony  in  connection  with  the  London  Medical 
School  this  year  took  an  unusual  form,  which  possessed 
the  merits  of  originality,  interest,  and  usefulness.  The 
customary  presentation  of  prizes  was  made,  and  short  ad- 
dresses were  delivered.  On  the  conclusion  of  these 
formal  proceedings,  the  field  at  the  back  of  the  hospital 
became  the  scene  of  further  operations,  and  being  lime- 
lighted, was  seen  to  be  transformed  into  a  battle-field 
strewn  with  the  dead  and  dying  remnants  of  a  defeated 
army.  To  these  entered  an  ambulance  corps,  the  mem- 
bers of  which  immediately  set  about  the  stem  business 
of  caring  for  the  injiured  militants ;  and  realism  was  still 
further  obtained  by  the  introduction  of  a  number  of 
ladies  in  the  red  cross  uniform. 


524 


THE  MEDICAL  RECORD.! 


[November  8,  i884. 


gletrieMJB  and  Notices* 


Hooper's  Physician's  Vade  Mecum  :  A  Manual  of  the 
Principles  and  Practice  of  Physic ;  with  an  Outline  of 
General  Pathology,  Therapeutics,  and  Hygiene.  Tenth 
Edition.     Revised  by  William  Augustus  Guy,  M.B. 
Cantab.,  F.R.S.,  Fellow  of  the  Royal  College  of  Phy- 
sicians ;   Late  Professor  of  Forensic   Medicine   and 
Hygiene,  King's  College,   London;  Consulting  Phy- 
sician to  King's  College  Hospital,  etc.,  etc.,  and  John 
Harley,  M.D.  Lond.,  F.L.S.,  Fellow  of  the  Royal 
College  of  Physicians;    Honorary   Fellow  of  King's 
College,    and  Late  Physician  to  the  London   Fever 
Hospital ;  Lecturer  on  General  Anatomy  and  Physi- 
ology at,  and  Physician  to  St.  Thomas'  Hospital.  Vol- 
ume II.     New  York  :  William  Wood  &  Co.  1884. 
The  second  volume  of  Hooper's  Manual  appears  as  the 
monthly  number  of  Wood's  Library,  following  immediately 
in  order  the  first  volume.     It  contains  the  greater  por- 
tion of  the  practical  part  of  the  work,  the  first  volume 
having  been  devoted  chiefly  to  an  outline  of  general 
pathology,  therapeutics,  and  hygiene.     At  the  end  of  the 
book  there  are  tables  of  remedies  and  formulae,  a  glos- 
sarial  index,  and  a  general  index.     As  to  the  value  of 
this  work,  we  can  only  repeat  what  was  said  in  noticing 
the  first  volume.     It  is  one  of  the  best  manuals  of  prac- 
tical medicine  in  existence,  complete  enough  to  serve  as 
a  guide  in  the  treatment  of  disease,  and  yet  so  compact 
as  to  allow  of  ready  reference  by  the  practitioner,  to 
whom  time  is  of  value. 

Corpulence  and  its  Treatment  on  Physiological 

Principles.     By  Dr.  Wilhelm  Ebstein.    Translated 

from  the  Sixth  German  Edition  by  Prof.  A.  H.  Keane. 

Wiesbaden  :  J.  F.  Bergmann.     New  York :  B.  West- 

ermann  &.  Co.    1884. 

We  have  already  reviewed  a  so-called  "  popular"  edition 

of  this  book.     We  have  nothing  to  add  concerning  it 

now,  except  to  recommend  it  as  a  most  suggestive  and 

useful  monograph.     The  present  edition  is  complete  and 

is  well  printed. 

The  Principles  or  Ventilation  and  Heating  and 
their  Practical  Application.  By  John  S.  Bil- 
lings, M.D.,  LL.D.  Pp.  214.  New  York  :  The  Sani- 
tary Engineer.  1884. 
Originally  written  as  a  series  of  papers  contributed  to 
the  Sanitary  Engineer^  the  material  composing  this 
work  has  been  rearranged  and  amplified  into  a  quite 
complete  and  most  readable  book.  The  author  has  en- 
tered into  his  task  with  an  evident  desire  to  supply  to 
the  medical  profession,  as  well  as  to  the  interested  in 
sanitary  matters  in  general,  much-needed  information  on 
a  highly  important  subject,  and  to  do  so  in  a  manner 
both  rational  and  practical.  In  this  rather  difficult  un- 
dertaking he  has  succeeded  most  admirably.'  He  first 
shows  the  impossibility  of  accomplishing  anything  in  the 
way  of  ventilation  without  some  knowledge,  at  least,  of 
the  principles  of  physics  as  affecting  the  relations  of 
gases ;  then  explains  these  principles  as  briefly  and 
clearly  as  could  be  desired  ;  and  finally  details  their  ap- 
plication to  private  dwellings,  churches,  theatres,  and 
hospitals.  He  maintains,  as  is  self-evident,  the  intimate 
connection  between  heating  and  air-supply,  and  shows 
the  absurdity  of  attending  only  to  the  one  to  the  neglect 
of  the  other.  He  then  considers  the  different  methods 
of  heating,  as  applied  to  the  various  kinds  of  buildings, 
always  with  a  view  to  securing  the  necessary  and  proper 
purity  of  the  air.  The  text  is  elucidated  by  drawings, 
particularly  of  plans  of  some  of  the  more  recent  and  im- 
proved structures,  explaining  their  merits  and  defects. 
In  short,  the  book  is  one  that  every  physician  should 
make  himself  familiar  with.  The  questions  of  hygiene, 
with  a  view  to  preventive  medicine,  are  constantly  as- 
suming greater  importance ;  and  among  them  that  of  sani- 
tary warming  and  ventilation  is  by  no  means  of  secondary 


importance,  and  one  with  which  the  medical  man  mast 
familiarize  himself.  Dr.  Billings'  book  will  tell  him  just 
what  he  wants  to  know.  The  author  is  one  of  a  class  of 
whom  we  have  unfortunately  too  few  in  this  country ; 
men  who  are  in  a  position  and  who  have  the  ability  and  in- 
clination to  apply  themselves  to  the  scientific  studies  of 
the  profession,  without  having  constantly  in  their  minds 
the  question  whether  the  result  can  be  utilized  in  their 
practice  so  as  to  bring  in  returns  in  dollars  and  cents. 
This  contributes  in  no  small  degree  to  that  judicial  fair- 
nesr>  of  mind  which  is  requisite  in  writing  to  instruct ; 
and  as  a  result  this  book  of  Dr.  Billings  is  noticeably 
free  from  bias  or  prejudice,  while  the  clear  and  forcible 
style  makes  the  work  interesting  as  well  as  instructive. 
Considering  the  value  of  the  book,  it  was  deserving  of 
better  treatment  at  the  hands  of  the  publishers  ;  the  type, 
though  clear,  is  small  and  very  trying  to  the  eyes.  If 
the  book  had  comprised  another  hundred  pages,  the  in- 
crease in  price  would  have  been  more  than  compensated 
for  by  the  ease  in  reading. 

A  Treatise  on  Physiology  and  Hygiene  for  Educa- 
tional Institutions  and  General  Readers.    By 
Joseph  C.   Huichison,  M.D.,  LL.D.,   ex-President 
of  New  York  Pathological  Society,  etc.     New  York|: 
Clark  &  Maynard.     1884. 
In  the  revised  edition  of  this  admirable  little  work,  con- 
siderable material  has  been  added  on  the  influence  of 
alcohol   and  narcotics   on  health.     Both   of  these  are 
treated  in  a  common  sense  manner.     Some  alterations 
are  made  throughout  the  text,  which  help  to  enhance  the 
value  of  the  book  for  beginners. 

Manual  of  Chemistry  :  A  Guide  to  Lectures  and  La- 
boratory Work  for  Beginners  in  Chemistry ;  A  Text- 
book specially  Adapted  for  Students  of  Pharmacy  and 
Medicine.  By  W.  Simon,  Ph.D.,  M.D.,  Professor  of 
Chemistry  and  Toxicology  in  the  College  of  Physicians 
and  Surgeons,  Baltimore,  Md.  8vo,  pp.  4x1.  Phila- 
delphia :  H.  C.  Lea's  Son  &  Co.  1884. 
This  is  a  book  for  careful  study  rather  than  for  the  casual 
reading,  either  of  the  beginner  or  the  advanced  student. 
The  mastery  of  its  various  lessons  means  work  from  begin- 
ning to  end  It  is  impossible  for  any  author  of  a  treatise 
on  chemistry  to  give  his  subject  the  attractiveness  of  a 
novel,  and  Professor  Simon  in  this  instance  has  certainly 
made  no  such  attempt.  He  does  his  duty  when  he  pre- 
sents his  subjects  in  all  their  nakedness  of  fact  and  stern- 
ness of  chemical  logic.  This  is  done  from  beginning 
to  end  in  an  almost  painfully  terse  manner.  The  work 
is  divided  into  seven  principal  parts,  which  are  naturally 
and  simply  arranged.  The  discussion  of  the  fundamental 
properties  of  matter  prepares  the  student  for  a  proper 
appreciation  of  general  chemical  phenomena,  next  fol- 
lows the  consideration  of  the  principles  of  chemistiy,  of 
the  non-metallic  and  metallic  elements,  the  old  classifica- 
tion being  in  the  main  adhered  to  ;  next  comes  qualita- 
tive analysis,  organic  chemistry,  and  physiological  chem- 
istry. It  will  thus  be  seen  that  the  general  subject  of 
the  book  is  quite  thoroughly  treated,  giving  the  student 
a  comprehensive  view,  and  preparing  him  for  most 
thorough  work  in  his  department.  It  contains  many 
beautifully  colored  plates  of  chemical  reactions,  which  are 
in  some  instances  made  with  the  actual  substance  when 
possessing  stability  of  color,  and  in  others  most  artistic- 
ally and  beautifully  tinted  by  the  talented  wife  of  the  au- 
thor.   

Inula  Campana  in  the  Treatment  of  Leucorrhcea. 
— Dr.  Charon  mentions  several  substances  which  he 
states  exert  a  beneficial  influence  in  leucorrhoea.  Among 
these  the  most  eflicacious,  he  thinks,  is  elecampane.  It 
is  given  in  infusion,  tincture,  extract,  or  powder  of  the 
root.  The  best  preparation  is  an  infusion  of  three 
drachms  of  the  root  in  five  ounces  of  boiling  water,  the 
whole  to  be  taken  in  the  morning. — Rivista  ClinUOy  No. 
8,  1884. 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


525 


&avKJ^Bpan&JmcJ^. 


"DEAD   TEETH    IN  THE  JAWS." 

To  THE  Eorros  op  Thb  Medical  Rbcoko. 

Sir  :  It  appears  that  the  allusions  to  "  pain  in  the  ears 
due  to  irritation  in  the  jaws,"  etc.,  under  '*  Hospital  Re- 
ports," and  my  comments  thereon  in  The  Record  of 
October  4th,  have  called  forth  dissenting  views  in  the 
two  subsequent  issues. 

Lest  silence  might  be  construed  as  yielding  assent  to 
your  correspondents'  views,  I  would  beg  space  to  reply 
briefly  to  some  of  their  strictures.  Before  so  doing,  how* 
ever,  it  might  be  well  to  state  that  the  cases  reported  by 
my  senior  assistant,  Dr.  Bartlett,  as  coming  to  the  ear 
clinic,  were  not  intended  to  specially  illustrate  dental  af- 
fections ;  but  it  was  believed  that  such  examples  of  re- 
flected dental  initation  would  not  be  devoid  of  interest 
to  the  profession.  The  extraction  and  filling  of  the  teeth, 
where  required,  it  may  be  said,  is  intrusted  to  our  own 
dentists,  who  are  competent  to  do  such  work. 

In  regard  to  the  exceptions  taken  to  the  concluding 
paragraph  of  the  report,  I  cannot  think  that,  from  a  clin- 
ical point  of  view,  the  statements  were  either  too  sweep- 
ing or  overdrawn.  Thus  the  retention  in  the  jaws  of 
teeth  which  are  diseased  from  death  of  the  pulp  or  from 
caries  have  become  irremediably  sensirive  to  thermal  in- 
fluences, or  have  been  deprived  of  adequate  periosteal 
nourishment  through  calcareous  formations  about  the 
roots,  very  frequently  gives  rise  to  nervous  diseases  about 
the  head.  I  am  convinced  that  these  reflected  nerve  in- 
fluences manifest  themselves  much  oftener  since  dentistry 
has  come  more  extensively  into  practice  during  the 
present  generation,  and  greater  efforts  are  made  to  retain 
defective  teeth  in  the  jaws;  and,  moreover,  the  very 
general  introduction  of  apparatus  for  retention  in  the 
mouth  of  substitutes  for  absent  teeth  is  apparently  ac- 
complishing much  harm  also.  Nor  does  the  energy  dis- 
played in  increasing  this  industry  not  give  promise  of 
speedy  reform.  I  am  not  sure  that  the  injurious  results 
aJluded  to  are  always  due  to  the  work  of  less  informed 
operators,  as  has  been  alleged,  since  it  has  been  my  lot 
to  have  frequently  seen  morbid  processes  kept  up  in  the 
ears  for  a  long  time  by  diseased  teeth  which  dentists  of 
repute  were  **  treating,"  and  speedy  recovery  has  followed 
the  tooth's  removal  Indeed,  while  writing  this  letter  a 
well-known  medical  man  who  practises  dentistry  in  this 
dty  came  to  consult  me  about  an  inflammation  of  one 
of  his  ears,  which  began  to  trouble  him  from  the  time 
the  upper  second  molar  of  that  side  was  "treated"  for  a 
diseased  pulp,  and  he  himself  is  convinced  that  the 
offending  tooth  lies  at  the  bottom  of  the  difficulty. 

The  gist  of  the  whole  matter,  however,  seems  to  lie  in 
the  question,  Whether  it  is  safe  practice  to  retain  dead 
teeth  in  the  jaws.  Teeth  seem  unlike  other  parts  of 
the  osseous  framework,  inasmuch  as  they  are  developed 
from  without,  so  to  speak,  and  are  afterward  left  con- 
stantly exposed  to  atmospheric,  chemical,  and  mechanical 
influences  liable  to  set  up  destructive  processes  in  this 
substance.  When  limited  caries  results,  its  progress  may 
be  interfered  Vith  for  a  longer  or  shorter  period  of  time 
by  stopping  the  cavity,  but  when  the  nutrition  of  so  large 
an  area  of  the  bone  is  interfered  with,  as  occurs  from 
death  of  the  pulp,  it  would  seem  that  in  a  large  number 
of  instances  irritation  cannot  be  so  easily  controlled,  and 
the  affected  tooth  becomes  more  or  less  of  a  foreign 
body,  since  the  moment  the  pulp  dies,  thus  cutting  off  the 
source  of  nutrition  from  the  dentine^  the  part  thus  nour- 
ished must  of  necessity  die  also.  In  fact  the  tooth,  hav- 
mg  a  vascular  or  nervous  supply  from  both  periosteum 
and  pulp,  the  impairment  of  either  must  affect  it. 

From  a  review  of  this  subject  we  were  further  led  to 
believe  that  in  the  case  of  no  dead  (pulpless)  tooth,  how- 
ever carefully  treated  and  filled,  can  it  ever  be  success, 
fully  demonstrated  that  a  slight  irritation  is  not  constantl 


present,  although  no  appreciable  irritation  may  be  ex- 
perienced by  the  patient. 

In  regard  to  the  treatment  of  pulpless  teeth,  the 
practice  in  vogue  seems  the  reverse  of  procedures 
founded  on  well-established  surgical  principles,  since 
stopping  the  natural  outlet  for  the  escape  of  putrescent 
products  from  portions  of  the  pulp  left  remaining  in  the 
canal  and  in  the  dental  canaliculi  through  the  exterior 
part  of  the  tooth  itself,  makes  their  passage  into  the  tissues 
underneath  unavoidable.  This  diversion  of  the  drainage 
must  be  of  questionable  propriety  in  many  instances,  since 
the  tissues  about  the  roots  of  dead  teeth  are  liable  to  be- 
come infiltrated  with  the  products  of  decomposition,  the 
absorption  of  which,  when  slowly  formed,  is  much  more 
liable  to  contaminate  the  system  than  the  discharge  of  pus 
into  the  mouth  from  an  alveolar  abscess.  Furthermore, 
inflammation  of  exposed  dentine  cannot  surely  be  entirely 
arrested  in  any  case  by  filling  the  pulp-cavity  with  any 
known  extraneous  material,  and  especially  is  handi- 
craft wanting  to  even  imperfectly  protect  the  minute 
and  often  tortuous  canals  leading  down  to  the  apical 
foramina  of  the  majority  of  the  teeth.  The  most  skilful 
operator  can,  under  these  circumstances,  at  best  but 
hope  that  his  work  will  not  soon  be  followed  by  trouble 
arising  from  the  escape  of  deleterious  matter  into  the 
tissues  about  the  root,  or  the  development  of  peri- 
cementitis. He  is  able  only  to  offer  a  hopeful  but  un- 
certain prognosis  in  these  cases,  but  the  patient  may  all 
the  same  remain  an  unconscious  sufferer  in  respect  to  the 
slow  but  persistent  irritation  of  the  surrounding  tissue  ; 
the  irritation  thus  propagated  from  the  dead  tissues  of  the 
dentine  will  sooner  or  later  most  likely  be  transmitted 
through  the  tissue  of  the  cementum  to  the  periosteum. 
It  is  true  that  through  the  periosteum  alone  the  dentine 
may  long  derive  some  nourishment,  yet  in  the  meantime 
periostitis  often  exists,  so  that  the  patient,  without  having 
actual  pain,  is  always  conscious  of  undue  tenderness 
about  the  root  of  the  dead  tooth,  which  may  be  much 
exacerbated  by  a  severe  cold  or  any  sudden  wrenching  of 
the  tooth,  as  in  biting  some  hard  substance.  A  person 
with  a  pulpless  tooth  in  his  jaw  which  has  been  stopped, 
cannot  even  consider  himself  free  from  the  danger  of 
reflected  irritation  and  its  various  consequences,  and  he 
may,  moreover,  at  any  moment  experience  more  or  less 
inflammation  about  its  roots. 

That  a  defective  tooth  in  many  instances  may  remain 
in  the  jaws  of  a  healthy  person  for  an  almost  indefinite 
period  without  doing  appreciable  harm,  surely  does  not 
warrant  the  risk  being  taken  in  avery  large  number  of 
cases,  since  what  may  be  tolerated  quite  well  in  the 
strong  and  robust  will  set  up  serious  trouble  in  those  who 
are  run  down  frc^n  any  cause,  in  subjects  of  catarrhal 
affections,  and  the  like  ;  in  these  the  more  an  offending 
tooth  is  "treated,"  the  worse  in  many  cases  it  will  be  for 
the  patient.  The  writer  has  been  much  impressed  by 
witnessing  the  sufferings  endured  by  weak  and  nervous 
persons  during  ineffectual  attempts  to  "treat"  and 
"  cure  "  their  pulpless  teeth,  and  he  cannot  but  regard 
such  practice  as  questionable.  Indeed,  his  experience 
in  practice  leads  him  to  believe  that  some  diseases  can- 
not be  successfully  treated  so  long  as  dental  irritation  is. 
maintained. 

It  is  in  respect  to  matters  of  this  kind  that  a  medical 
opinion  is  often  much  needed.  The  question  of  the 
usefulness  of  retained  dead  teeth  in  certain  cases  is  of 
such  importance  that  persons  are  willing  to  assume 
more  or  less  risk  to  health  rather  than  be  deprived  of  a 
useful  grinder  or  an  ornamental  incisor — these  are  ques- 
tions which  no  discussion  can  ever  settle. 

Samuel  Sexton,  M.D. 

X2  West  Thirty-fifth  Street,  New  York,  October  a8,  1884. 

An  American  Physician  to  Deliver  the  Gul- 
STONiAN  Lectures. — Prof.  Wm.  Osier,  of  Philadelphia, 
will  deliver  the  Gulstonian  Lectures  at  the  College  of 
Physicians,  in  London,  in  1885. 


526 


THE  MEDICAL  RECORD. 


[November  8,  1884. 


PROFESSOR    ALFRED    L.    LOOMIS    ON    COL- 
ORADO  CLIMATE. 

To  THk  Editor  op  Thb  Medical  Rbcord. 

Sir  :  Of  the  recent  medical  publications  there  is  perhaps 
none  that  is  receiving  more  general  attention  from  the  pro- 
fession than  Professor  Alfred  L.  Loomis's  **  Practical 
Medicine,"  and  there  is  probably  no  portion  of  this  work 
which  will  be  more  eagerly  read,  or  which  will  carry  more 
weight,  than  that  which  has  reference  to  pulmonary 
troubles,  and  especially  to  the  climatic  cure  of  phthisis. 
The  wide-spread  reputation  of  the  author  as  a  diagnosti- 
cian in  these  troubles,  and  his  well-known  experience, 
will  give,  in  the  mind  of  the  general  reader,  the  weight  of 
authority  to  whatever  he  may  say  on  these  points. 

That  Professor  Loomis  places  great  stress  on  the  cle- 
ment of  climate  in  the  cure  of  phthisis  is  seen  by  his  as- 
sertion that  "each  year's  experience  impresses  on  me 
the  conviction  that  while  climate,  more  than  any  other 
agent,  has  a  controlling  influence  over  phthisical  develop- 
ments, each  case  must  be  carefully  analyzed  before  any 
definite  directions  can  be  given  as  to  the  climate  best 
suited  to  it." 

To  the  medical  profession  of  the  Rocky  Mountain 
region  this  question  is  of  such  vital  interest  that  our  first 
point  of  investigation,  on  receiving  the  "Practical  Medi- 
cine," was  to  see  what  Professor  Loomis  had  to.say  about 
our  climate.  Our  curiosity  was  whetted  the  more  be- 
cause of  our  remembrance  that,  in  his  treatise  on  the 
"Diseases  of  the  Respiratory  Organs,  Heart,  and  Kid- 
neys," page  281,  he  has  committed  himself  to  the  opin- 
ion that  "  the  climate  of  Colorado  is  mild  and  peculiarly 
dry,  from  its  elevation  ;  the  atmosphere  is  highly  ex- 
hilarating and  peculiarly  healthful.  Here  flowers  grow 
at  the  height  of  eight  thousand  feet ;  usually  at  a  much 
less  height  vegetation  does  not  flourish.  The  rainfall 
for  one  year  was  about  sixteen  inches.  In  some  sections 
there  are  but  slight  variations  of  temperature  throughout 
the  year.  The  winter  days  are  those  of  a  northern  sum- 
mer ^  and  the  summer  is  but  little  warmer  than  winter T 
(The  italics  are  mine.) 

What  was  our  surprise,  then,  to  read  in  his  "  Practical 
Medicine,"  page  205,  that  "there  is  one  grave  objection 
to  Colorado  as  a  winter  refuge — the  enormous  monthly 
and  also  diurnal  range  of  temperature  must  severely  try 
any  invalid.  During  March,  1880,  the  thermal  range  at 
Denver  was  eighty-three  degrees,  and  in  December, 
1876,  it  amounted  to  ninety-three  degrees ;  a  change  in  a 
single  month  greater  than  occurs  at  London  in  a  whole 
year,  and  greater  than  occurs  at  New  York  in  a  whole 
winter." 

Certainly  there  is  a  wide  variance  between  these  two 
opinions,  and  as  it  is  not  to  be  presumed  that  the 
character  of  the  Colorado  climate  has  been  changed  to 
such  a  degree,  in  a  few  years,  as  these  two  quotations 
would  lead  one  to  suppose,  the  reader  can  simply  con- 
clude that  Professor  Loomis' s  personal  experience  of  our 
Colorado  climate  has  led  him  to  change  his  views,  and 
that  he  no  longer  holds  that  our  "  winter  days  are  those 
of  a  northern  summer." 

The  writer  is,  however,  somewhat  doubtful  whether 
this  would  be  a  correct  conclusion,  and  he  thinks  it  more 
probable  that  Professor  Loomis  has  been  misled  by  others 
in  his  opinion  expressed  in  the  "Practical  Medicine." 
My  reason  for  thinking  so  is,  that  in  looking  over  the 
files  of  the  New  York  Herald^  under  date  of  December 
29,  1883,  in  an  editorial  entitled  "  Winter  Resorts  for 
Invalids,"  beginning  :  "  Dr.  S.  A.  Fisk,  writing  from 
Denver,  recently  published  in  Science  an  interesting 
paper  containing  the  results  of  an  extensive  investiga- 
tion of  the  relative  merits  of  different  American  sanitaria 
in  the  cure  of  consumptives,"  I  find  the  following : 
"  But  there  is  one  apparently  grave  objection  to  Colo- 
rado as  a  winter  refuge,  which  Dr.  Fisk  seems  to  esti- 
mate too  lightly.  The  enormous  monthly  and  also 
diurnal  range  of  temperature  must  severely  try  any  inva- 


lid. During  March,  1880,  the  thermal  range  at  Denver 
was  83  degrees,  and  in  December,  1876,  it  amounted  to 
93  degrees — a  change  in  a  single  month  greater  than  oc- 
curs at  London  in  a  whole  year,  and  greater  than  occurs 
at  New  York  in  a  whole  winter." 

Further  on  in  the  *'  Practical  Medicine,"  pages  206 
and  207,  is  the  following,  viz. :  "  Recently  Davos  am 
PlatZy  in  the  Swiss  Alps,  has  been  most  extensively  vis- 
ited. Williams,  Albutt,  and  other  English  physicians 
give  very  favorable  reports  of  it.  It  is  5,200  feet  above 
the  sea,  very  dry,  but  not  windy,  and  not  changeable. 
Davos  possesses  also  the  unique  climatic  characteristic 
of  freedom  from  high  winds  (the  records  showing  that 
firom  October  i,  1880,  to  March  31,  188 1,  there  were  one 
hundred  and  thirty-four  days  with  *  no  wind  %  while  its 
*  sun  temperature '  rises  even  in  January,  as  Dr.  Frank- 
lin notes,  as  high  as  150^ — conditions  which  admit  of 
much  invaluable  out-door  exercise  by  invalids.  Doubt- 
less some  high  winter  resort  combining  these  vitalizing 
conditions*  can  be  found  in  the  Southwestern  Rocky 
Mountain  region  of  our  own  country." 

From  the  editorial  already  cited  I  quote  the  follow- 
ing :  "  Davos  possesses  also  the  unique  climatic  charac- 
teristic of  freedom  from  high  winds  (the  records  showing 
that  from  October  i,  1880,  to  March  31,  1 881,  there 
were  one  hundred  and  thirty-four  days  of  *  no  wind  \ 
while  its  *  sun  temperature  '  rises  even  in  January,  as  Dr. 
Franklin  notes,  as  high  as  150°— conditions  which  admit 
of  much  invaluable  our-door  exercise  by  invalids.  Doubt- 
less some  high  winter  resort  combining  these  vitalizing 
conditions  can  be  found,  as  Dr.  Fisk  suggests,  in  the 
Southwestern  Rocky  Mountains." 

These  quotations  seem  to  me  to  justify  the  conclusion 
that  in  speaking  of  the  Colorado  climate,  Professor 
Loomis  has  drawn  from  the  statements  of  others  rather 
than  given  the  results  of  his  own  experience. 

To  be  sure,  he  may  have  been  responsible  for  the 
editorial  from  which  I  have  quoted,  but  a  comparison  of 
the  two  following  passages  makes  me  think  that  this  can- 
not be. 

In  the  "Practical  Medicine," page  206,  he  says:  "The 
extraordinarily  dry  belt  of  country  which  runs  northward 
from  San  Antonio,  Texas,  has  begun  to  endanger  the 
supremacy  of  Florida  as  a  health  resort  for  the  consump- 
tive. That  this  belt  offers  some  climatic  advantages  for 
weak  lungs  over  the  mild  but  rather  humid  air  of  Florida 
cannot  be  doubted." 

In  the  editorial  cited  is  the  following  :  "Another  writer 
in  the  Philadelphia  Medical  Times  has  also  recently 
called  attention  to  the  virtues  of  our  western  climate  m 
the  treatment  of  consumption,  and  expresses  the  opinion 
that  *  the  extraordinarily  dry  belt  of  country'  which  runs 
northward  from  San  Antonio,  Texas,  has  begim  to  en- 
danger the  supremacy  of  Florida  as  a  winter  health  resort 
for  the  consumptive.'  That  this  belt  offers  some  climatic 
advantages  for  weak  lungs  over  the  mild  but  rather 
humid  air  of  Florida  cannot  be  doubted" 

I  should  like  to  call  attention  to  the  fact  that  Pro- 
fessor Loomis  speaks  of  the  air  of  Florida  as  being 
"  rather  humid,"  and  yet  a  little  earlier,  on  the  same  page 
of  his  "  Practical  Medicine,"  he  publishes  the  following  : 
"  Minnesota  has  a  dry,  cool,  exhilarating  climate.  South- 
ern California,  Georgia,  and  South  Carolina  have  a  dry, 
warm  atmosphere." 

Now  the  records  of  the  Signal  Service  Bureau,  U.  S. 
Army,  accessible  to  anyone,  show  that  the  mean  relative 
humidity,  for  a  series  of  four  years,  was  from  65°  to  69° 
of  saturation  for  Minnesota,  Southern  California,  South 
Carolina,  and  Georgia.  We  give  the  data,  viz.:  Augusta, 
Ga.,  69.2°  ;  Jacksonville,  Fla.,  69"* ;  St.  Paul,  Minn., 
67.3°;  Los  Angeles,  Cal.,  65.8°;  Denver,  Col.,  45-8'. 
These  figures,  together  with  the  maps  published  by  the 
Signal  Service  Bureau,  at  the  earnest  solicitation  of  the 
Colorado  State  Medical  Society,  prove  conclusively  that 
if  the  air  of  Florida  is  "  rather  humidy*  that  of  Southern 
California,  Georgia,  and  South  Carolina  cannot  be  called 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


527 


"</ry"— certainly  not  in  comparison  with  the  dry  air  of 
the  Rocky  Mountain  region. 

In  conclusion,  the  writer  wishes  to  state  that  the  two 
instances  of  the  extreme  range  of  temperature,  cited  by 
the  editorial  writer  and  also  by  Professor  Loomis,  are 
correct,  and  are  taken  from  the  records  of  the  Signal 
Service ;  yet  it  seems  to  him  that  the  citation  of  such  un- 
usual ranges  is  calculated  to  give  an  erroneous  impres- 
sion of  our  climate,  for,  as  a  rule,  our  winter  days  are 
warm  and  pleasant,  so  that  it  is  not  uncommon  for  per- 
sons to  sit  with  doors  and  windows  open,  or  to  have  pic- 
nics in  the  open  air,  even  in  the  heart  of  January.     The 
illustrations  cited  may  do  very  serious  injury  to  a  climate 
whose  beneficial  eflfects  "  are  incontestibly  proved  by  hun- 
dreds of  cases,''  and  they  may,  especially  when  given  the 
weight  of  Professor  Loomis's  authority,  deter  invalids 
from  coming  to  a  place  of  which  so  impartial  a  writer  as 
Dr.  Edward  T.  Ely  has  remarked  :  "  Colorado  can  easily 
rest  on  its  own  merits.     .     .     .     Despite  all  objections 
which  may  be  raised,  the  climate  is  probably,  as  we  have 
aheady  said,  the  very  best  of  its  kind  at  present  available 
for  invalids,  and  destined  to  grow  in  popularity  as  its 
merits  become  more  accurately  understood." 

Samuel  Aug.  Fisk,  M.D. 

373  Curtis  Stkbjbt,  Dkmvex,  Col. 


BRIEP    NOTE    ON  THE    TREATMENT  OF 
FRACTURE   OF  THE   CLAVICLE. 

To  THK  Editor  of  Thb  Mbdical  Record. 

Sir:  Fracture  of  the  clavicle  is  one  of  those  ailments 
which  are  not  so  serious  as  troublesome,  from  the  diffi- 
culty of  keeping  the  fractured  ends  in  apposition.  All 
the  various  apparatus  for  that  purpose  have  failed,  and 
the  consequence  of  failure  is  a  protuberance  on  the  point 
of  fracture,  persisting  through  life,  unsightly  if  not  incon- 
venient 

To  avoid  this  result  I  propose  the  following  plan  of 
treatment :  Turn  the  arm  of  the  affected  side  behind  the 
back,  and  bring  it  as  far  backward  as  possible  in  such 
manner  that  the  dorsal  side  of  the  hand  comes  to  lie  on 
the  opposite  buttock.  To  retain  this  position  it  is  neces- 
sary only  to  fix  a  narrow  strip  of  adhesive  plaster  around 
the  wrist  and  thence  around  the  body,  or  the  whole  arm 
may  be  fixed  on  the  body  by  means  of  a  roller  bandage 
from  under  the  axilla  down  to  the  crista  ilias. 

I  have  adopted  this  plan  for  the  last  two  years,  treat- 
ing in  that  way  about  a  dozen  cases  (with  one  exception, 
aU  children),  and  the  result  in  every  case  was  a  speedy 
union  without  deformity.  The  only  drawback  is  the 
difficulty  of  lying  down,  and  in  fact  in  my  first  case,  a 
girl  of  ten,  the  patient  sat  up  in  a  chair  day  and  night  for 
two  ^eeks,  but  I  found  after  a  while  that  the  children 
are  able  to  obtain  perfect  rest  sleeping  on  the  sound  side. 

S.  Teller,  M.D. 

306  West  Thirtv-thiru  Street,  New  York. 


"THE  HEMORRHOID  QUACK." 

To  THE  Editor  op  The  Medical  Record. 

Sir  :  A  propos  of  the  communication  which  you  published 
in  a  recen:  issue  from  Dr.  Stevens,  of  Chillicothe,  Mo., 
and  in  view  of  the  fact  that  all  parts  of  the  country  are 
infested  by  a  class  of  illiterate,  incompetent,  and  un- 
authorized "  doctors  "  who  advertise  to  "  cure  piles  with- 
out pain,"  etc.,  I  desire  to  report  the  following  case  which 
has  very  recently  fallen  under  my  notice.  • 

General  ,  a  retired  army  officer,  has  long  been  a 

friend  and  occasional  patient,  his  general  health  being 
much  impaired  from  chronic  cystitis  and  gastro-intestinsd 
catarrh.  He  b  a  monomaniac  on  the  subject  of  quacks 
and  their  remedies,  and  I  suppose  he  has  dosed  himself 
with  about  every  "  safe "  and  sure  cure  ever  concocted. 
The  literature  of  suburban  rocks  and  fences  is  to  him  a 
gospel,  and  the  testimonials  of  eminent  judges  and  divines 
are  revelations. 


Several  days  since  I  was  summoned  in  haste  to  see  the 
General.  On  arriving  I  found  him  in  great  pain,  which 
he  referred  to  the  rectum,  and  explained  by  saying  that 
he  had  been  operated  upon  for  piles,  a  few  days  previ- 
ously, by  a  *'  doctor  "  whose  advertisement  he  had  read, 
and  who  had  exhibited  a  number  of  very  flattering  testi- 
monials from  officers  of  the  army  and  navy.  Upon  ex- 
amination I  found  a  sloughing  ulcer  upon  the  site  of  what 
had  evidently  been  an  external  hemorrhoid.  The  bowels, 
too,  he  said,  were  acting  very  frequently,  and  seemed  to 
be  beyond  voluntary  control.  Packing  the  sore  with 
iodoform,  and  prescribing  three  drops  of  laudanum  to  be 
taken  ever}*  two  hours,  with  the  object  to  heal  the  wound, 
control  the  pain,  and  restrain  the  bowels,  I  withdrew. 

The  wound  progressed  well,  but  in  spite  of  opium, 
both  by  the  mouth  and  rectum,  frequent  semi-involun- 
tary alvine  evacuations  occurred.  Three  days  after  I 
first  saw  him  he  had  a  sudden  and  enormous  discharge  of 
clotted  and  fluid  blood  mingled  with  fecal  matter.  The 
odor  was  horrible.  I  now  gave  injections  of  ergot  and 
hamamelis,  and  ordered  opmm  suppositories  to  be  con- 
tinued. For  forty-eight  hours  all  went  well,  when  there 
was  another  copious  discharge  of  very  offensive  matter, 
consisting  of  blood,  feces,  and  pieces  of  dark-colored 
membranous  shreds  and  flakes.  The  patient  was  in  a 
state  verging  upon  collapse,  and  complained  greatly  of 
pain  and  pressure  in  the  rectum.  The  pulse  was  weak 
and  intermittent;  surface  cool  and  bleached,  and  coun- 
tenance pinched.  Vomiting  came  on,  and  things  began 
to  look  serious.  Examining  the  anus  I  saw  a  dark  and 
putrid  substance  protruding,  and,  drawing  upon  it,  suc- 
ceeded in  extracting  about  three  inches  of  what  proved 
to  be  a  portion  of  the  mucous  membrane  of  the  rectum. 

I  was  prevented  from  delivering  the  entire  mass  by  at- 
tachments at  the  anal  margin,  and  had  to  detach  with 
scissors.  Learning  now  that  the  quack  had  used  some 
sort  of  injection,  which  I  concluded  was  carbolic  acid, 
and  that  he  had  either  injected  a  number  of  hemor- 
rhoidal tumors,  or  had  ignorantly  allowed  a  quantity  of 
the  solution  to  enter  the  bowel,  I  saw  that  I  had  to  deal 
with  a  case  of  inflammatory  sloughing  of  the  lining  mem- 
brane of  the  rectum.  Digital  exploration  revealed  rough- 
ness and  great  tenderness,  and  ocular  inspection  with  a 
speculum  showed  an  extensively  denuded  surface,  con- 
gested and  bleeding.  Seeking  to  control  any  further 
hemorrhage  and  evacuative  efforts,  I  now  cleared  away  all 
debris,  and,  through  the  speculum,  packed  the  bowel 
tightly  with  absorbent  cotton  soaked  in  a  strong  solution 
of  glycerine  and  tannin,  and  afterward  inserted  a  sup- 
pository containing  two  grains  of  opium.  This  treat- 
ment, I  am  happy  to  say,  proved  effective,  and  I  believe 
my  indiscreet  friend  is  out  of  danger. 

Well,  here  is  an  instance  where  an  intelligent  man 
places  hiniself  under  the  care  of  an  impudent  pretender 
for  a  disease  which  we  all  treat  with  the  greatest  caution, 
and  always  with  anxiety;  and  he  almost  pays  the  penalty 
with  his  life.  This  pile-driver  insisted  on  our  friend  tak- 
ing his  usual  exercise,  and  did  not  even  consider  it  nec- 
essary to  see  him  again  after  the  operation.  But  what 
are  we  to  do  about  it  ?  The  public  are  free  to  consult 
whom  they  choose,  and  the  religious  press  continues  to 
spread  the  glad  tidings  of  the  miraculous  performances 
of  any  and  every  impostor  who  w^pay  their  regular  price. 

Unfortunately  such  results  as  here  narrated  are  not 
generally  circulated.     Very  respectfully, 

Geo.  B.  Fowler,  M.D. 

II  West  Forty-fifth  Street,  New  York. 


THE    PREVALENCE    OF    CONSUMPTION     AT 
DIFFERENT  AGES  OF  LIFE. 

To  the  Editor  of  The  Medical  Recobd. 

Sir  :  It  may  be  of  interest,  in  relation  to  the  communi- 
cations of  Drs.  Holden  and  Baker,  in  The  Record  of 
July  1 2th  and  August  30th,  relative  to  the  above  subject, 
which  having  been  absent  I  have  but  just  observed,  to 


528 


THE  MEDICAL  RECORD. 


[November  8,^1884. 


present  some  results  and  conclusions  found  by  myself  in 
i860.  They  are  embodied  in  a  paper,  afterward  pub- 
lished, read  by  me  before  the  American  Geographical 
and  Statistical  Society.  Up  to  that  time  these  statistics 
relative  to  the  mortality  from  consumption  under  various 
conditions  of  climate^  age,  sex,  etc.,  were  the  most  exten** 
sive  that  had  appeared,  one  table  comprising  27,771,728 
deaths  from  all  diseases  occurring  in  various  parts  of  the 
world  between  1804  and  i860.  In  this  paper  I  have 
given  three  tables  illustrative  of  its  prevalence  at  various 
ages,  the  first  from  Boudin  ("  Geographic  et  Statistiques 
M6dicales") ;  the  second,  constructed  by  myself,  of  88,- 
427  deaths  from  consumption  occurring  in  various  cities 
and  countries ;  and  the  third,  constructed  by  me  from  the 
Registrar-General's  reports  of  deaths  in  England  from 
1848  to  1852,  in  1856,  and  in  London  in  1857. 

The  table  of  M.  Boudin  relates  to  the  deaths  from 
consumption  in  England  and  Wales  in  1847.  It  shows 
that  of  53,317  deaths  there  occurred — 


Under  the  age  of  5  years 9  per  cent 

Between  5  and  10  years 3. i        *' 

**      10    ••     20      "    7.5 

"      ao  "  30  ••  14-7 

••      30  "  40  "  26.4 

40  "  50  •'  12.8 

50  ••  60  *•  7.9 

60  '*  70  ••  4.6 

"       70  ••  80  •'  1.3 

80  "  90  ••  ai4 

Above  90  ••  0^035    *' 


The  second  table  shows  that  of  the  88,427  who  died 
from  consumption — 

25.5  per  cent,  died  between  the  ages  of  20  and  30 ; 


20.S 

ia.3 

"3 

7-7 

6.4 

1.3 


30    ••    40; 

*'  "      10    "    20; 

"     40    "    50; 

birth  and  10  years  of  age ; 

the  ages  of  50  and  60 ; 

"      60    -    70; 

"      70    '*    8a 


It  has  been  variously  stated  by  writers  (I  quote  from 
my  paper)  that  consumption  is  developed  at  an  earlier  age 
among  females  than  among  males.  The  following  table 
shows  this  is  not  true  before  the  tenth  year,  yet  between 
that  time  and  the  forty-fifth  year  the  various  decades  fur- 
nish a  greater  percentage  of  deaths  among  the  females 
than  the  males;  but  that  after  the  forty-fifth  year  the  per- 
centage is  greater  among  the  males. 

Third  table,  of  409,862  deaths  occurring  in  England 
and  in  London  : 

Males.  Females. 

Under  5  years  of  age 8.4  per  cent  6.9  per  cent. 

Between  5  and  15  years 6.2       *'  7.8 

**     15    '*    25      **     22.92     •*  26.1        '* 

"     25    "    35      ''     22.6       ''  24.9        " 

"     35    '*    45      "     16.9        '*  170 

;*     45    *'    55      '*     11.9        ^'  9-5 

55    "    65      *'     0.7       •*  5.2 

65    '»    75      "     a.i        "  2.2        *' 

"     75    **    85      **     0.02      **  0.03      " 

To  save  space,  I  have  not  given  in  the  above  tables 
the  full  figures,  that  is,  the  number  of  deaths  at  each 
epoch,  but  have  simply  calculated  the  percentages. 

Though  I  recognize  the  cogency  of  Dr.  Holden*s  state- 
ment, that,  in  order  to  show  the  age  at  which  death  from 
consumption  is  most  liable  to  occur,  the  proportion  of 
the  deaths  to  the  number  of  the  living  should  be  con- 
sidered, and. that Ja  large  proportion  of  deaths  from  it  at 
ages  when  there  are  the  greatest  number  living,  does  not 
show  that  it  is  most  liable  to  occur  at  those  ages  ;  still,  the 
above  tables,  I  think,  are  of  equal  value  in  showing,  with- 
out regard  to  the  living,  the  periods  when  death  from  the 
disease  is  most  liable  to  occur. 

Yours  truly, 

H.  B.  Millard,  M.D. 

Xew  York,  October  ao,  1884. 


A  PHYSICIAN»S  EXPERIENCE  IN  HIS  OWN 
FAMILY  IN  CHILDBIRTH  AND  INFANT 
FEEDING. 

To  TKB  Editor  op  Thb  Mkdical  Rbcokx>. 

Sir  :  Your  readers  will  all  recall  the  discussion  of  puer- 
peral fever  in  The  Record  last  winter.  My  wife's  term 
of  gestation  ended  in  March ;  she  always  had  been  in 
delicate  health  ;  there  was  considerable  of  the  fever  in 
our  city,  and  fatal  in  many  cases,  one  young  lady  dying 
with  it  only  a  few  doors  from  us  a  week  or  two  before 
my  wife's  confinement. 

.  It  will  not  be  hard  for  any  one  to  imagine  my  condi- 
tion of  mind  as  the  time  passed.  Whether  I  was  to  fol- 
low  the  advice  of  our  most  enlightened  teachers  on  the 
subject  or  not  constantly  worried  me,  as  doubtless  it 
does  many  others  in  similar  cases  now. 

Finally,  however,  I  followed  the  advice  of  our  South- 
em  brother,  who  advised  throwing  away  the  bed-pan  and 
having  the  patient  sit  up  several  times  a  day  to  urinate, 
and  used  no  internal  wash  of  any  kind,  but  kept  every 
thing  scrupulously  clean  around  her.  My  wife  did  per- 
fectly well  without  any  trouble,  and  I  for  one  am  con- 
vinced  that  it  is  wrong  to  fully  follow  the  advice  of  one 
of  our  teachers  and  keep  the  patient  austerely  on  her 
back  for  fear  of  post-partum  hemorrhage.  To  more 
fully  indicate  my  feelings  I  will  add  that  for  the  month 
of  March  I  refused  to  attend  other  cases,  and  turned 
away  ten,  I  think,  as  I  for  one  feel  fully  convinced  that 
the  fever  is  very  often  carried  to  patients  both  by  the 
physician  and  also  by  the  nurse. 

After  a  few  weeks  my  wife  lost  her  milk  and  was  un- 
able to  nurse  the  baby  at  all.  Now  I  was  in  another 
trouble.  From  my  own,  and  the  experience  of  others,  I 
knew  that  a  bottle-fed  baby,  here  in  the  city,  stood  a 
very  poor  show  for  living,  and  that  many  that  did  live 
were  poor,  feeble,  emaciated  little  beings.  I  read  up 
almost  everything  on  the  subject  of  infant  food,  and  tried 
some  of  the  well-known  preparations,  in  combination 
with  milk,  which  I  never  fully  gave  up,  but  they  did  not 
seem  to  work  satisfactorily.  I  sent  the  baby  in  the 
country,  but  it  was  troubled  there  more  than  ever,  dur- 
ing a  wet  period  in  July  which  we  had. 

Finally,  I  got  extractum  pancreatis  and  followed  the 
directions,  only  I  used  more  than  half  water,  and  when 
he*  was  troubled  the  most  and  his  food  seemed  to  pass 
entirely  undigested,  I  used  two-thirds  water.  The  baby 
began  to  improve  at  once,  and  is  now  one  of  the  health- 
iest babies  around  here.  I  kept  him  in  the  country — Or- 
ange County — where  he  could  have  fresh  morning's  milk, 
until  near  the  middle  of  this  month,  September.  When 
bom  he  weighed  a  little  less  than  eight  pounds ;  now  he 
is  one  week  over  six  months  and  weighs  almost  three 
times  as  much,  his  flesh  is  solid,  and  he  looks  far  better, 
and  is  as  large  as  many  babies  one  year  old.  I  con- 
tinued to  use  the  pancreatis,  but  do  not  follow  the 
directions.  I  take  nearly  two-thirds  milk  oflf  the  ice,  add 
the  pancreatis  and  soda,  then  add  hot  water  and  feed  at 
once.  At  ni^ht  I  prepare  two  bottles  and  put  on  ice,  or 
outside  the  window  when  cool,  although  we  rarely  need  but 
one,  and  often  do  not  use  any.  If  needed  in  the  night 
I  heat  on  an  alcohol  stove  in  a  few  minutes,  and  give  at 
once.  The  good  derived  from  the  pancreatis  is  all,  or 
nearly  all,  done  in  the  stomach. 

The  strangest  part  of  it  is  that  the  baby  seems  to  do 
fully  as  well,  and  we  think  better,  on  the  milk  we  get  here 
in  the  city. 

My  conclusions  are  that  babies  can  be  brought  up  on 
milk  easily  and  well  under  favorable  circumstances. 
Pancreatis  and  soda  aid  materially,  especially  if  the  food 
has  been  passing  or  rejected  in  an  undigested  state. 

But  I  believe  it  is  far  more  important  to  dilute  the 
milk  with  one-half,  and  often  in  young  babies  with  two- 
thirds,  water.  And  above  all  things  keep  the  feet  warm 
and  have  the  diapers  both  dry  and  warm. 

Respectfully,  G.  F. 

NfCWAXK,  N.  J. 


November  8,  1884.] 


THE  MEDICAL  RECORD. 


529 


^ewr  %n6tvnmmte. 


A  NEW  MODIFICATION    OF  BARNES*  DI- 
LATOR. 
By  GEORGE  COWAN,  M.D., 


DANMLLK,   KV. 


Having  had  some  practical  experience  recently  of  the 
difficulties  not  unfrequently  met  with  in  introducing  and 
retaining  in  situ  during  their  expansion  the  Barnes'  dila- 
tors, I  have  had  constructed,  for  future 
use,  by  Messrs.  Tiemann  &  Co.,  of 
New  York,  a  modification  of  this  ap- 
paratus, which,  it  is  hoped,  may  in  some 
measure  remove  the  troubles  met  with 
in  their  use. 

In  the  Barnes*  dilator  the  pocket 
into  which  the  probe  is  inserted  for 
introducing  the  bag  serves  as  a  serious 
obstruction  to  its  easy  introduction,  be- 1 
sides  being  placed  externally  and  to 
one  side  of  the  bag — a  very  unsuitable 
point  upon  which  to  direct  the  force 
which  is  to  guide  and  push  the  dilator 
into  its  place  in  the  canal.  Further- 
more, the  distal  extremity  is  unneces- 
sanly  blunt  or  flat. 

In  the  second  place,  it  is  a  flat  oval 
on  cross-section,  while  the  cervical  ca- 
nal, when  partially  dilated,  is  probably 
more  nearly  cylindrical  in  form.  The 
consequence  is  that  neither  the  waist 
nor  extremities  of  the  dilator  can  be 
expanded  so  as  to  give  it  the  form  best 
adapted  for  its  retention  when  the  cer- 
vix has  been  slightly  dilated. 

The  modification  which  I  have  had 
made,  and  which  the  accompanying  dia- 
gram will  serve  to  illustrate,  is  circular 
on  transverse  section  throughout  its 
length,  and  has  a  tapering  distal  extrem- 
ity for  its  easy  introduction  into  the 
cer\'ix  uteri.  The  probe  which  accom- 
panies it  is  a  small  brass  rod,  having  a  small  button- 
shaped  extremity,  and  is  introduced  through  the  gum 
tube  to  the  inside  of  the  bag,  and  finally  lodged  in  the 
centre  of  the  extremity,  thus  enabling  the  bag  to  fold 
and  adjust  itself  neatly  and  closely  around  the  probe 
during  its  passage  through  the  cervix  and  along  the  canal, 
while  the  force  is  applied  in  the  most  advantageous  po- 
sition, />.,  inside  the  dilating  bag. 

I  beg  to  offer  these  modifications  of  the.  Barnes*  dila- 
tors to  the  consideration  of  the  profession  as  better 
adapted,  I  trust,  to  successfully  imitate  nature's  inimita- 
ble provision  for  dilating  the  cervix. 


A  NEW  SCROTAL  COMPRESSOR. 
By  JESSE  HAWES,  M.D., 

GREELEY,  COL. 

Let  me  call  the  attention  of  that  portion  of  the  profes- 
sion who  have  to  deal  with  inflamed  testicles  to  a  device 
recently  made  at  my  request  by  Tiemann  &  Co. 

It  is  composed  of  two  rubber  bags,  the  inner  one  easily 
distensible,  one  within  the  other,  and  united  so  as  to  form 
an  air-tight  compartment  between  the  outer  and  inner 
layers.  This  double  bag  is  open  on  one  side  from  the 
"  mouth  "  nearly  to  the  bottom ;  on  each  side  of  this 
opening  or  "slit"  are  cemented  pieces  supplied  with 
eyelets  ;  a  small  rubber  tube  perforates  the  outer  layer 
and  is  cemented  carefully  to  it.  Other  pieces  are  at- 
tached to  its  upper  part  to  aid  in  suspending  it  to  a  waist- 
belt. 


The  double  bag  is  sufficiently  large  to  receive  the 
largest  swollen  testicle.  Placing  the  testicle  within  the 
bag,  its  mouth  completely  encircling  the  cord,  the  slit  is 
carefully  closed  by  lacing ;  air  is  then  blown  from  the 


mouth,  or  by  a  syringe,  through  the  rubber  tube  into  the 
air-tight  space.  The  compression  is  perfectly  equal  and 
can  be  exerted  to  any  extent  desired  ;  the  air  is  prevented 
from  escaping  by  simply  bending  and  tying  the  tube. 

Its  advantages  are  these  :  Hot  water  can  be  conveyed 
into  the  air-tight  space,  giving  us  a  warm  or  hot  applica- 
tion. A  cloth  moistened  (^.  ^.,  with  a  lead  and  opium  wash) 
can  be  applied  about  the  testicle  before  placing  it  in  the 
compressor.  One  compressor  will  fit  all  sizes  of  testicle. 
There  is  no  need  of  shaving  the  scrotum.  It  is  applied 
in  a  moment.  When  the  swelling  has  decreased  the 
elasticity  of  the  rubber  still  continues  to  exert  a  moderate 
pressure,  and  the  patient  himself  may  in  a  moment  in- 
crease the  pressure  if  it  is  desired.  In  short,  in  my  ex- 
perience, its  cleanliness,  its  perfectly  equal  compression, 
the  ease  with  which  it  is  managed,  and  the  comfort  it 
gives  the  patient,  seem  to  fill  every  requirement  that  a 
compressor  should  have. 

Official  List  iff  Changes  in  the  Stations  ondDuiiis  cf  Officers 
serving  in  the  Medical  Department ^  United  States  Army, 

from  October  26  to  November  i,  1884. 

Alden,  C.  H.,  Major  and  Surgeon.  In  addition  to 
his  duties  at  Fort  Snelling,  Minn.,  to  perform  the  duty 
of  attending  surgeon  at  Department  Headquarters.  S. 
O.  127,  Headquarters  Department  of  Dakota,  October 
23,  1884. 

Town,  F.  L.,  Major  and  Surgeon.  Assigned  to  tem- 
porary duty  as  Post  Surgeon,  Fort  Clark,  Texas.  S.  O. 
145,  Department  of  Texas,  October  27,  1884. 

Bentley,  Edwin,  Major  and  Surgeon.  To  be  re- 
lieved from  duty  at  Fort  Clark,  Texas.  S.  O.  145,  De- 
partment of  Texas,  October  27,  1884. 

Wilson,  W.  J.,  Captain  and  Assistant  Surgeon.  As- 
signed to  temporary  duty  at  Fort  Trumbull,  Conn.  S.  O. 
220,  Department  of  the  East,  October  27,  1884. 

CoRBUSiER,  W.  H.,  Captain  and  Assistant  Surgeon. 
Assigned  to  duty  at  Fort  Bowie,  Arizona  Territory.  S.  O. 
99,  Department  of  Arizona,  October  22,  1884. 

La  Garde,  L.  A.,  Captain  and  Assistant  Surgeon. 
Assigned  to  duty  at  Fort  Ellis,  Montana  Territory,  re- 
lieving First  Lieutenant  G.  E.  Bushnell,  Assistant  Sur- 
geon U.S.A.,  who,  upon  being  relieved,  will  report  for 
duty  at  Fort  Snelling,  Minn.  S.  O.  126,  Department  of 
Dakota,  October  22,  1884. 

Everts,  Edward,  First  Lieutenant  and  Assistant  Sur- 
geon. Leave  of  absence  extended  one  month.  S.  O. 
107,  Headquarters  Division  of  the  Pacific,  October  21, 
1884. 

McCaw,  Walter  D.,  Fir§t  Lieutenant  and  Assistant 
Surgeon.  Ordered  from  Fort  Craig,  New  Mexico,  to 
Fort  Wingate,  New  Mexico,  for  duty.  S.  O.  92,  Head- 
quarters District  of  New  Mexico,  October  21,  1884. 


530 


THE  MEDICAL   RECORD* 


[November  Si  1884, 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  November  i,  1884. 

Beardslev,  Grove  S.,  Surgeon.  To  Washington,  D. 
C,  for  examination  preliminary  to  promotion,  and  as  to 
qualifications  for  sea  duty.     October  31,  1884. 

Craig,  Thomas  C,  Passed  Assistant  Surgeon.  To 
the  Alliance  for  temporary  duty.     October  31,  1884. 

Gardner,  James  E.,  Passed  Assistant  Surgeon.  To 
the  Naval  Hospital,  Norfolk,  Va.     October  28,  1884. 

Hall,  John  H.,  Passed  Assistant  Surgeon.  From  the 
Naval  Hospital,  New  York,  to  the  Navy  Yard,  Mare 
Island,  Cal.     October  29,  1884. 

HoRD,  William  T.,  Medical  Director.  To  continue 
duty  as  member  of  the  Retiring  Board  until  January  i, 
1885.     October  27,  1884. 

LovERiNG,  P.  A. ,  Passed  Assistant  Surgeon.  To  the 
Naval  Dispensary,  Washington,  D.  C,  for  temporary 
duty.     October  27,  1884. 

Turner,  Thomas  J.,  Medical  Director.  To  continue 
duty  as  member  of  the  Retiring  Board  until  January  i, 
1885.     October  27,  1884. 

Steele,  John  M.,  Passed  Assistant  Surgeon.  To  the 
Naval  Hospital,  New  York.     October  29,  1884. 


piedical  Itjems. 


Contagious  Diskasbs — ^Wbbkly  Statkmbmt. — Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  November  i,  1884 : 


Week  Ending 


Cas€s, 

October  25, 1884 . 
November  i,  1884 

Dtaiks, 
October  25,  1884 . 
November  i,  1884 


I 


I 


I 


The  Ownership  of  a  Medical  Curiosity. — The 
newspapers  report  a  very  curious  case  in  a  Virginia  court. 
A  police  officer  of  the  city  of  Petersburg,  named  William 
Shank,  was  for  a  considerable  time  visibly  growing  weak- 
er and  thinner,  while  his  appetite  continued  enormous, 
when  one  day  last  week  he  vomited  a  hideous-looking 
lizard  about  ten  inches  long  and  two  inches  in  circum- 
ference. The  lizard  was  dead  when  ejected,  and  was 
thrown  away.  It  was  found  and  presented  to  Dr.  John 
B.  Hartweli,  a  homoeopathic  physician,  who  put  it  in 
alcohol  to  preserve  it.  Dr.  Shank,  a  brother  of  the 
policeman,  heard  of  this  and  demanded  the  specimen 
from  Dr.  Hartweli,  who  agreed  to  give  it  up  if  payment 
was  made  for  the  trouble  and  expense  of  preserving  the 
curiosity.  Dr.  Shank  refused  to  make  any  such  payment, 
and  brought  suit  in  one  of  the  inferior  courts  for  unlaw- 
ful detention,  and  secured  judgment  against  Dr.  Hart- 
well.  The  latter  has  appealed  the  case  to  the  Hustings 
Court,  and  the  respective  claims  of  the  two  physicians 
will  there  be  determined. 

The  Question  of  Isolation  in  the  Infant  Hos- 
pitals OF  Paris. — If  one  may  judge  from  the  numerous 
complaints  appearing  from  time  to  time  in  the  medical 
journals  of  Paris,  the  management  of  the  hospitals  in  that 
city  is  far  from  being  satisfactory.  Among  all  the  papers 
the  Frogris  Midical  is  conspicuous  for  its  increasing 
eflforts  to  bring  about  reforms  in  this  department  of  the 
government.     In  a  recent  editorial  it  takes  the  Adminis- 


tration de  r Assistance  Publique  sharply  to  task  for  its 
culpable  neglect  in  the  matter  of  isolation  in  the  hos- 
pitals for  children.  It  is  only  within  the  last  five  years 
that  any  pretence  has  been  made  of  keeping  children 
with  diphtheria  apart  from  the  other  inmates  of  the  hos- 
pitals,  and  in  one  of  these  a  separate  pavilion  for  diph- 
theria patients  was  only  erected  in  May,  1882.  But  as 
far  as  other  diseases  are  concerned  there  is  not  at  the 
present  day  the  slightest  provision  made  for  isolation. 
So  glaring  is  this  evil  and  so  well  known  that,  as  was 
asserted  not  long  ago  by  Dr.  Maunoir,  these  hospitals 
have  a  reputation  among  certain  portions  of  the  popula- 
tion of  being  where  superfluous  children  can  be  lawfully 
and  at  *the  same  time  effectually  disposed  of.  In  one  of 
the  three  services  of  one  of  the  three  hospitals  in  the  year 
1881,  fifty-two  children  contracted  measles  in  the  wards* 
and  thirty  of  these  died.  By  a  simple  process  of  addition 
the  writer  calculates  that  two  hundred  and  fifty  children 
are  sacrificed  in  the  three  hospitals  every  year  by  measles 
alone,  and  by  measles  contracted  within  the  hospital  walls 
He  adds  that  by  a  low  estimate  the  number  of  victims 
of  contagion  from  all  diseases  in  the  infant  hospitals  of 
Paris  may  be  set  down  at  five  hundred  annually.  Such 
a  state  of  affairs  seems  almost  incredible,  and  one  would 
suppose  that  the  facts  in  the  case  could  never  have  been 
presented  to  the  authorities.  Yet  the  writer  asserts  that 
it  is  not  through  ignorance  that  the  administration  sins, 
for  its  attention  has  been  called  time  and  again  to  these 
and  other  abuses,  but  without  avail.  The  authorities  sit 
by  supinely  and  fold  their  hands  while  five  hundred  little 
innocents  are  sacrificed  every  year  to  their  brutal  indif- 
ference. We  are  accustomed  in  this  country  to  rail 
against  our  public  officials  and  to  think  that  in  no  other 
land  are  the  people's  servants  so  indifferent  to  the 
people's  wants.  But  very  few  citizens  of  New  York 
would  care,  we  imagine,  to  exchange  our  Commissioners 
of  Charities  and  Correction  for  the  Administration  de 
TAssistance  Publique  of  Paris. 

The    Mental   States    induced   by   Fright. — The 
Wiener  Medizinische   Wochenschrift^  of  July  19,  1884, 
contains  an  abstract  of  an  interesting  account  of  the 
earthquake  at  Ischia,  written  by  Dr.  Fazio,  an  eye-witness 
of  the  scene.     The  emotions  awakened  by  the  catas- 
trophe were  of  the  most  varied  character.     During  the 
fifteen  seconds  that  the  shock  continued  everybody  stood 
still,  seemingly  rooted  to  the  ground  with  terror.     Men 
were  weak  in  the  knees  and  shook  as  with  ague,  feeling 
as  though  they  were  about  to  fall,  but  none  of  them  had 
convulsions,  delirium,  or  syncope.     But  soon  this  stillness 
was  broken  by  loud  cries  and  howls,  and   everyone 
rushed  toward  the  shore.     Then  women  and  children  fell 
into  convulsions  or  appeared  to  be  semi-paralyzed  and 
speechless.     Rudeness  and  brutality  were  mingled  with 
self-sacrifice  and  heroism  of  the  most  exalted  character. 
Six  hours  after  the  catastrophe  the  stillness  of  death 
reigned  over  Casamicciola.     Men  wandered  about  the 
ruins  half  clad  and  silent  as  if  risen  from  the  grave; 
women  were  excited  and  hysterical ;  children  of  eight  or 
ten  years  seemed  dazed  and  stupefied,  while  smaller  chil- 
dren stood  around  unconcernedly  eating  whatever  they 
could  find  in  the  ruins.     It  is  most  interesting  to  see  the 
different  ways  in  which  [individuals  were  affected  by  the 
shock.     The  keeper  of  a  refreshment  booth  who  had  lost 
ever)rthing  kept  offering    his  delicacies   to   those  who 
passed  by,  just  as  though  everything  had  not  been  swept 
away.      A    surgeon,   covered    with  blood  and    sorely 
wounded  by  the  fallen  beams,  was  concerned  only  for 
his  instruments,  and  inquired  after  them  of  everybody 
whom  he  encountered.     An  hysterical  woman,  who  had 
been  bed-ridden  for  months,  jumped  up  and  saved  her- 
self by  flight,  and  remained  permanently  cured.    Many 
who  were  at  first  brave  and  full  of  energy  became  later 
depressed  and  apathetic,  or  had  convulsions  or  alternate 
fits  of  laughter  and  crying.    Sometimes  a  melancholia  was 
induced  which  continued  for  months,  and  many  became 
incurably  insane.     Abortion  was  very  common,  and  there 


November  8,  1S84.] 


THE  MEDICAL  RECORD. 


531 


were  many  cases  of  suddenly  arrested  menstruation.  The 
sexual  appetite  was  universally  destroyed  for  many  days 
after  the  earthquake,  and  in  many  instances  there  was 
also  an  aversion  to  food.  There  were  numerous  cases  of 
retention  of  urine,  sometimes  lasting  for  days  and  de- 
manding catheterization.  There  were  several  instances 
in  which  the  hair  was  whitened  by  fright,  and  even  some 
boys  of  ten  to  fourteen  years  showed  heads  sprinkled 
with  gray.  Many  of  those  buried  in  the  ruins  exhibited 
the  greatest  indifference  to  their  fate,  following  listlessly 
with  their  eyes  the  motions  of  those  busied  in  their  rescue. 
A  foreign  officer  whose  legs  were  imprisoned  under  some 
heavy  timbers  drew  out  a  cigarette  and  smoked  it  with 
the  utmost  nonchalance.  One  man,  as  soon  as  he  was 
palled  from  the  ruins,  shook  his  rescuer  by  the  hand  and 
presented  him  with  his  card.  Another,  who  lay  beneath 
the  debris  for  twenty  hours,  immediately  looked  at  his 
watch  in  order  to  record  the  exact  instant  of  his  deliver- 
ance. A  lady  who  had  just  been  extricated  from  a  mass  of 
rubbish  would  not  budge  from  the  spot  until  she  could  as- 
certain the  fate  of  her  pet  dog,  which  was  buried  with  her. 
One  woman  who  heard  a  man  calling  for  his  daughter, 
deceived  him  so  cunningly  that  she  was  rescued  by  him 
before  the  trick  was  discovered.  Most  of  the  people, 
however,  who  were  imprisoned  beneath  the  ruins  were 
too  indifferent  to  their  fate  to  attempt  any  such  deception, 
and  most  of  them  had  not  the  slightest  idea  of  the  length 
of  time  during  which  they  were  buried.  Most  of  those 
who  were  wounded  by  the  falling  buildings  underwent 
the  necessary  surgical  operations  without  experiencing 
any  pain,  though  some  were  hyperaesthetic. 

What  Constitutes  Unchastity. — ^A  curious  point  as 
to  the  proper  admission  of  testimony  was  presented  on 
the  appeal  of  a  case,  where  the  action  was  for  slander  in 
charging  an  unmarried  woman  with  unchastity.  The 
defendent,  in  answer,  alleged  that  there  was  such  an  in- 
crease in  the  size  and  such  a  change  in  the  physical 
appearance  of  the  plaintiff  as  to  induce  him  to  believe 
that  she  was  pregnant.  One  of  the  witnesses  on  his  be- 
half was  a  woman  who  had  borne  children,  and  who  was 
asked  if  the  plaintiff,  as  to  her  physical  appearance,  ap- 
peared like  women  do  when  they  are  pregnant  This 
question  was  not  allowed,  and  the  appeal  from  the  ruling 
was  the  main  point  to  be  decided.  The  court  held  that 
it  was  proper  to  ask  a  witness  his  opinion  whether  a 
person  was  drunk,  because  that  fact  is  better  determined 
by  the  direct  answer  of  the  witness  than  by  any  descrip- 
tion of  the  person's  conduct^  and  that  there  was  a  simi- 
larity between  such  a  case  and  that  where  the  fact  of 
pregnancy  was  involved.  The  court  was  of  the  opinion 
that  '*  if  the  appearance  of  the  plaintiff,  from  any  cause, 
was  such  that  women  who  had  had  experience  would  testify 
that  she  appeared  like  a  pregnant  woman  physically,  the 
testimony  certainly  was  important  to  mitigate  the  damages 
to  which  the  defendant  might  be  subjected.  And  if  the 
plaintiff  insists  that  the  witnesses  should  have  stated  the 
facts  in  detail,  in  order  that  the  jury  might  judge  whether 
plaintiff's  appearance  was  like  that  of  a  pregnant  woman, 
it  is  obvious  that  no  description  of  enlargement  of  size 
and  the  like  would  convey  an  accurate  idea  of  the  plain- 
tiffs whole  appearance."  It  was  therefore  decided  that 
it  was  proper  to  ask  the  opinion  of  the  witness  whether 
the  appearance  of  the  plaintiff  was  like  that  of  a  pregnant 
woman. 

Is  Cankibalism  Necessarily  Murder? — A  very 
interesting  case  will  shortly  be  brought  to  trial  in  Eng- 
land, to  determine  whether  cannibalism  is  necessarily 
murder.  The  facts  are  these :  The  yacht  Mignonette, 
under  Captain  Dudley,  was  disabled  in  a  gale  between 
Madeira  and  the  Cape  Colony  last  July,  and  the  crew, 
consisting  of  the  captain,  two  men,  and  a  boy,  took  to 
the  boat.  They  soon  exhausted  their  small  supply  of 
provisions,  and  no  help  was  at  hand  in  mid-ocean.  Af- 
ter a  little  they  caught  a  turtle,  and  this  sustained  life  for 
some  days.     When  this  was  eaten,   starvation  began. 


After  some  days  it  was  proposed  that  they  should  cast 
lots  to  see  which  should  die  to  save  the  others,  but  this 
plan  was  rejected.  When  fifteen  days  had  passed  with- 
out food,  after  further  debate  it  was  decided  that  the  boy, 
who  was  very  weak  and.  sinking  fast,  should  die,  and  the 
captain,  after  asking  God  to  pardon  what  he  was  about 
to  do,  killed  the  youth.  For  three  days  the  survivors 
subsisted  on  the  boy's  flesh,  and  then  a  passing  vessel 
picked  them  up  and  took  them  into  Falmouth.  Captain 
Dudley  did  not  conceal  the  facts,  but  promptly  reported 
them,  not  expecting,  apparently,  that  he  would  be  held 
criminally  liable.  The  authorities  of  Falmouth,  however, 
arrested  him  on  his  own  sworn  statement,  and  the  trial 
for  murder  will  soon  take  place.  It  will  be  seen  that 
these  circumstances  are  quite  different  from  those  of  the 
Greely  party,  as  there  only  the  flesh  of  the  dead  soldiers 
wfis  eaten.  The  moral  question  is  much  the  same,  how- 
ever, and  the  Dudley  case  will  certainly  give  rise  to  great 
discussion  as  to  the  propriety  of  eating  human  flesh  under 
any  circumstances.  It  should  be  remembered  that  in 
the  case  of  the  Mignonette  the  killing  of  the  youth,  no 
doubt,  saved  the  lives  of  the  others,  and  had  not  this 
been  done  all  would  have  probably  died.  This  does  not 
affect  the  moral  aspect  of  the  case  if  the  act  was  wrong 
under  any  conditions,  nor  does  the  further  fact  that  the 
boy  would  soon  have  died  from  nsttural  causes ;  but  these 
circumstances  will  inevitably  have  some  effect  upon  a 
jury  called  upon  to  determine  whether  Captain  Dudley 
shsdl  die  for  his  act.  The  question  of  insanity  will  also 
assume  a  prominent  position  on  the  trial,  for  it  is  cer- 
tainly a  matter  for  investigation  whether  persons  exposed 
to  the  weather  for  fifteen  days  in  an  open  boat,  without 
any  food,  are  responsible  for  their  acts.  The  outcome  of 
the  trial  it  is  not  difficult  to  surmise,  for  no  matter 
whether  public  sentiment  abstractly  condemns  Captain 
Dudley's  conduct  or  not,  it  is  not  at  all  likely  that  any 
jury  will  bring  in  a  verdict  of  guilty  of  murder.  The 
chances  are  wholly  in  favor  either  of  a  disagreement  or 
acquittal. 

Sublimate  Injections  in  Joint  Diseases. — Professor 
Vogt  has  obtained  good  results  in  three  cases  of  so-called 
gonorrhoeal  rheumatism  of  the  knee  by  intra-articular 
injection  of  corrosive  sublimate.  He  employed  a  solu- 
tion of  bichloride  of  mercury,  i^  grain  ;  chloride  of 
sodium,  15  grains;  distilled  water,  12  drachms.  Of  this 
solution  45  to  75  minims  were  injected  into  different 
parts  of  the  joint.  The  injections  were  repeated  every 
four  days,  but  how  long  the  treatment  was  continued  the 
author  does  not  state.  At  the  time  when  these  cases 
were  reported  he  stated  that  the  cure  could  be  regarded 
as  established,  massage  and  passive  motions  being  all  that 
was  necessary  to  restore  the  functions  of  the  joint.  In 
other  non-specific  bone  and  joint  diseases  a  somewhat 
extensive  employment  of  this  mode  of  treatment  leads 
the  author  to  believe  that  "in  certain  cases  much  can  be 
accomplished  by  intra-articular  injections  of  corrosive 
sublimate." — Centralblatt fur  Chirurgie^  August  23, 1884. 

Does  Decapitation  Cause  Instant  Death? — ^We 
noticed  recently  some  experiments  made  by  M,  Laborde 
with  the  head  of  Campi,  who  was  executed  in  Paris  for  a 
murder,  which  almost  seemed  to  show  that  life  might  be 
retained  for  a  time  in  a  decapitated  head  by  supplying 
the  brain  artificially  with  blood.  The  publication  of  these 
results  in  the  Revue  Scientifique  has  called  forth  a  com- 
munication from  another  writer  who  witnessed  an  execu- 
tion in  Saigon  some  years  ago,  a  brief  account  of  which 
we  abstract  from  the  Tribune  M^dicale  of  August  10, 
1884.  Decapitation  in  Annam,  it  seems,  is  performed 
by  a  single  sword  stroke  on  the  neck,  the  criminal  kneel- 
ing down  and  being  forced  to  flex  the  head  so  as  to  sep- 
arate as  widely  as  possible  the  vertebrae.  Thus  it  some- 
times happens  that  the  cord  is  severed  by  a  clean  cut 
without  being  either  contused  or  concussed.  The  writer 
being  desirous  to  ascertain  whether  consciousness  were 
retained  in  the  separated  head,  attracted  the  attention 


532 


THE.  MEDICAL  RECORD. 


[November  81 1884. 


of  the  criminal  to  himself  by  speaking  in  a  loud  tone  to 
one  of  the  officials  just  before  the  execution  took  place. 
He  was  successful  in  this,  for  the  condemned  man  looked 
up  and  gazed  intently  at  the  speaker  for  a  moment.  He 
then  knelt  down  and  received  the  death-stroke.  It  so 
happened  that  the  head  in  falling  did  not  roll,  but  rested 
upright  on  the  sand  in  such  a  way  that  the  flow  of  blood 
from  the  veins  of  the  neck  was  arrested.  In  an  instant 
the  eyes  were  opened  and  fixed  themselves  upon  the 
writer,  who  stood  very  near.  He  moved  quickly  to  one 
side  and  the  eyes  followed  him ;  then  he  returned  more 
slowly  to  his  former  position,  and  the  eyes  turned  again 
in  that  direction.  They  followed  him  but  for  an  instant, 
however,  and  were  then  suddenly  turned  away,  while  an 
agonized  expression  overspread  the  features,  the  mouth 
opened  spasmodically,  and  the  face  seemed  to  gasp  for 
breath.  The  movement  of  the  jaw  overturned  the  head 
and  it  rolled  on  the  sand  and  gave  no  further  signs  of 
life.  Could  the  cerebral  circulation  have  been  main- 
tained in  this  case  as  it  was  in  that  of  Campi,  by  connect- 
ing the  vessels  with  an  opened  artery  of  a  dog,  the  results 
might  have  been  startling  enough  to  disturb  even  the 
most  phlegmatic  experimenter. 

The  Value  of  Cinchonidia. — Dr.  J.  Weichselbaum, 
of  Savanna,  Ga.,  writes  us  in  reference  to  the  editorial 
in  The  RECORd  of  July  19th,  upon  the  value  of  cinchoni- 
dia. He  states  that  "  in  the  female  ward  of  the  Savan- 
nah Hospital,  the  service  of  Dr.  R.  J.  Nunn,  we  have 
been  using  the  sulphate  of  cinchonidia  ior  some  time. 
We  use  the  following  formula  : 

5 .  Cinchonidia  sulph gr.  v. 

Sodii  bicarb gr.  v. 

M.  S. — One  dose  for  adult ; 
with  the  same  result  that  we  had  with  the  sulphate  of 
quinine.  We  used  it  in  all  cases  we  would  have  used 
the  sulphate  of  quinine.  We  never  had  any  of  the 
trouble  complained  of  by  Professor  J.  Marty."  Our 
correspondent  adds  that  of  late  he  has  been  using  the 
alkaloid  cinchonia  given  with  soda,  and  has  had  equally 
good  results.  The  inference  from  Dr.  Weichselbaum's 
experience  is  that  quinine  is  no  safer  or  surer  than  its 
cheaper  allies.  This  is  against  the  experience  of  the  pro- 
fession, and  invalidates  completely  Dr.  W.'s  observations. 

A  Case  of  Cancer  of  the  Pancreas — Autopsy. 
— Dr.  F.  W.  Epley,  of  New  Richmond,  Wis.,  sends  us 
the  following :  "  In  view  of  the  fact  that  the  literature 
upon  affections  of  the  pancreas  is  exceedingly  limited  ; 
that  some  of  our  standard  works  on  pathology  pass  over 
the.  organ  with  the  simple  remark  that  *  the  pancreas  is 
seldom  examined  for  disease,'  and  give  no  further  direc- 
tions in  regard  to  the  post-mortem  examination  of  said 
organ,  and  that  in  the  light  of  more  frequent  autopsies 
consequent  upon  death  from  obscure  causes  we  can  ap- 
proach nearer  the  truth  in  these  pathological  assertions, 
I  have  reached  the  conclusion  that  it  is  the  duty  of  every 
medical  man  to  report  cases  which  come  under  his  notice 
where  obscure  or  questionable  cases  have  been  cleared 

up  by  an   autopsy.      On   May  25,   1884,  Sam  M 

came  into  my  office  and  told  me  he  wanted  me  to  see  if 
I  could  find  out  *  what  in  h — 1  ailed  him.'  I  give  his 
own  words,  for  they  are  not  void  of  significance  in  this 
case.  He  stated  that  he  had  begun  to  feel  badly  soon 
after  walking  a  long  distance  through  snow-drifts  in  the 
February  preceding.  He  lost  his  appetite;  had  some 
uneasiness  about  the  epigastrium  ;  had  a  nasty  taste  in 
his  mouth  ;  had  not  slept  a  wink  for  weeks,  and  '  then 
these  d— d  black  janders  come  onto  him  and  he  wanted 
to  die  if  I  couldn't  give  him  something  to  relieve  him.' 
He  was  restless,  weak,  but  constantly  moving,  and  was 
even  more  impatient  than  his  language  indicates.  He 
was  a  farmer^  well-to-do,  always  quiet  and  always  indus- 
trious. Upon  examination  I  found  him  only  fairly  nour- 
ished ;  evidently  losing  flesh ;  extremely  icteric^  and 
covered  with  an  eruption  simulating  bromism,  which  kept 
him  constantly  scratching.     His  stools  were  entirely  de- 


void of  color ^  except  that  of  prepared  chalk.  This  pecu- 
liarity was  constant.  I  found,  about  two  inches  to  the 
right  of  the  umbilicus,  a  small  hard  tumor,  apparently 
about  the  size  of  a  small  tea^cup,  but  more  pointed.  It 
was  hard  but  freely  movable.  It  was  not  easily  to  be 
seen,  but  by  close  attention  the  abdominal  parietes  could 
be  seen  to  glide  over  the  tumor.  I  diagnosed  malignant 
disease,  either  in  liver  or  structures  closely  approximat- 
ing it,  and  contrary  to  my  custom  gave  up  the  case  at 
once,  communicating  the  facts  to  his  wife.  He  went  to 
other  physicians,  and  finally  struck  a  lead  on  two  homoeo- 
pathic doctors,  who  *  cured  him  till  he  died '  on  Decern- 
ber  loth,  following.  Autopsy  revealed  cancer,  scirrhous 
form,  in  head  of  pancreas,  which  had  drawn  up  about  the 
common  duct  of  the  liver  to  such  an  extent  that  it  was 
impossible  to  separate  the  duct,  or  in  fact  to  distinguish 
it  by  the  naked  eye  from  the  pancreatic  tissue.  Henct 
the  jaundice.  There  was  no  obstruction  in  bowels  or 
stomach,  and  no  other  structure  was  involved  to  any  ex- 
tent, except  a  portion  of  the  lesser  omentum.  It  occurs 
to  me  that  the  disease  mtut  have  originated  in  the  head 
of  the  pancreas,  thereby  occluding  the  common  duct  and 
occasioning  the  early  and  persistent  jaundice.  The  tu- 
mor near  the  umbilicus  proved  to  be  a  distended  galU 
bladder.  The  liquid  it  contained  was  of  a  pearly  hue  and 
quite  viscid." 

Treatment  of  Skin  Diseases  at  Vienna. — ^A  corre^ 
spondent  of  the  British  Medical  Journal  writes :  "  In 
Professor  Kaposi's  wards  the  permanent  bath-beds  are  in 
constant  use.  Bums,  ulcers,  and  obstinate  syphilides  are 
here  treated ;  in  the  latter  cases,  weak  solutions  of  per- 
chloride  of  mercury  may  be  used  with  advantage  ;  in  the 
cases  of  bums,  the  patients  express  themselves  as  being 
most  comfortable ;  after  being  in  the  *  bed '  a  few  mo- 
ments all  pain  is  lost,  and  there  is  no  dread  of  change 
of  dressings,  for  none  are  used.  Not  only  does  the  slough 
separate  and  the  wound  clean,  but  cicatrization  progresses, 
it  is  said,  more  rapidly  in  the  water  than  under  any  other 
treatment.  Psoriasis  is  usually  treated  with  pyrogallic 
acid,  10  per  cent,  in  traumaticin ;  goa  powder  in  the 
same  combination  is  also  used.  In  the  treatment  of 
superficial  lupus,  iodoform  in  solution,  with  collodion  or 
pyrogallic  acid  as  an  ointment,  is  used ;  the  former  b 
usually  applied  after  the  affected  part  has  been  mbbed 
with  a  strong  solution  of  caustic  potash.  Several  cases 
of  lichen  scrofulosomm  have  been  effectually  treated  with 
cod-liver  oil  internally,  and  as  an  external  application. 
A  few  weeks  ago  a  young  man  was  admitted  into  the 
wards  suffering  from  what  was  at  first  supposed  to  be 
merely  a  case  of  severe  intertrigo,  affecting  the  perineum 
and  surrounding  parts.  The  severe  general  disturbance, 
however,  led  Professor  Kaposi  to  diagnose  impetigo  her- 
petiformis. This  disease,  of  which  only  about  a  dozen 
cases  are  on  record,  is  usually  found  in  women,  and  ap* 
pears  to  be  in  some  way  connected  with  pregnancy  and 
the  puerperal  period  ;  one  case,  related  by  Heitzman,  oc- 
curred about  the  time  of  the  climateric.  Two  cases  only 
are  on  record  where  recovery  has  taken  place.  The  term 
herpes  pyaemicus,  of  Auspitz,  was  upheld,  as  the  disease 
is  one  which  is  probably  pyaemic  in  origin,  while  its  pro- 
gression is  marked  by  the  formation  of  small,  closely 
aggregated,  innumerable  bodies,  which  are  pustular  from 
the  commencement.  From  the  first  the  case  was  asso- 
ciated lyith  high  and  irregular  temperatures,  and  the  pa- 
tient was  treated  with  antipyretics,  simple  dressings  being 
applied.  The  affection,  however,  gradually  spread  upward 
over  the  abdomen,  and  smaller  patches  appeared  else- 
where. The  patient  gradually  sank  into  a  somnolent 
condition  ;  later  he  was  removed  into  one  of  the  perma- 
nent bath-beds,  where  he  appeared  more  comfortable,  and 
the  open  surfaces  more  healthy ;  it  was  specially  noticed 
that  this  change  produced,  in  addition,  immediate  and 
sustained  lowering  of  the  temperature.  The  patient,  how- 
ever, gradually  sank,  and  on  post-mortem  examination 
general  peritonitis  with  effusion  into  the  peritoneal  cavity 
was  found.'' 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  20 


New  York,  November  15,  1884 


Whole  No.  732' 


(Ihrigitml  Ji^trtijcles* 


A  NEW  THERAPEUTIC  USE   FOR   COCAINE. 
By  F.  H.  bos  worth,  M.D., 

NBW  YORK. 

In  using  a  solution  of  cocaine  in  the  nasal  cavity  for  its 
anaesthetic  effect  I  have  observed  an  action  which  has, 
as  far  as  I  know,  not  been  recorded.     When  the  solution 
is  applied  to  the  mucous  membrane  it  is  followed  in  about 
twenty  or  thirty  seconds  by  a  very  notable  contraction  in 
the  venous  sinuses  underlying  the  part  which  it  reaches, 
and  as  the  application  is  continued  over  the  whole  mem- 
brane covering  the  lower  and  middle  turbinated  bones 
these  sinuses  become  so  rigidly  contracted  that  all  the 
blood  which  they  may  have  contained  is  absolutely  ex- 
pelled, and  the  membrane  clings  closely  to  the  bony 
structures,  which  then  become  visible  in  absolute  outline. 
This  action    of  the  cocaine    was  so   entirely   unex- 
pected to  me  in  the  first  case  in  which  I  observed  it  that 
I  continued  my  observations  in  a  number  of  cases,  and 
in  no  single  case  out  of  over  forty  observed  carefully  has 
it  failed  to  produce  the  same  result.    Every  drop  of  blood 
was  expelled  from  the  erectile  tissue  in  each  case.     The 
strength  used  was  a  two  per  cent  solution,  and  it  was 
applied  by  means  of  a  pledget  of  cotton  wrapped  on  a 
small  probe.     The  effect  was  usually  observed  in  a  few 
seconds;    entire  depletion  of  the  sinuses  of  the  whole 
cavity  being  accomplished  in  about  three  minutes,  the 
production  of  anaesthesia,  as  a  rule,  requiring  a  longer 
^^ 

The  practical  value  of  the  use  of  the  cocaine  cannot, 
I  think,  be  overestimated,  for  we  possess  no  other  remedy 
which  can  be  depended  upon  to  produce  this  result  The 
morbid  conditions  in  which  I  observed  its  action,  and  in 
which  it  is  of  especial  value,  are  as  follows  : 

Hypertrophy  of  the  nasal  mucous  membrane, — ^This  is 
by  far  the  most  frequent  cause  of  a  nasal  catarrh,  and  its 
rational  treatment  demands  the  use  of  caustics  or  other 
destructive  agent  The  use  of  any  caustic  is  followed  by 
an  intense  turgescence  of  the  venous  sinuses  of  the  nose, 
which  is  a  source  of  distress  for  hours,  and  even  days,  after 
its  use. 

I  have  cauterized  the  mucous  membrane  of  the  nose 
in  twenty-seven  cases  since  I  observed  the  above-men- 
tioned action  of  cocaine.  The  application  was  ren- 
dered comparatively  painless  by  the  drug,  but  the  tur- 
gescence of  the  membrane  came  on  in  a  few  minutes 
after  the  caustic  was  used.  By  gently  bathing  the  swollen 
part  with  the  cocaine  the  turgescence  subsided  perma- 
nently, and  the  cauterization  was  accomplished  with- 
out pain  or  the  subsequent  discomfort  which  so  generally 
follows  its  use. 

Another  and  very  notable  value  of  this  action  of  the 
cocaine  is  as  an  aid  to  diagnosis  in  these  cases  of  hy- 
pertrophy. In  an  ordinary  case  of  this  kind  it  is  not 
possible  to  determine,  on  ocular  inspection,  how  much 
of  the  swelling  of  the  membrane  is  due  to  connective- 
tissue  hypertrophy  and  how  much  is  due  to  turgescence 
of  the  venous  sinuses.  By  applying  the  cocaine  to  the 
membrane  the  element  of  venous  turgescence  is  entirely 
eliminated,  and  the  amount  of  genuine  hyperplasia  can 
easily  be  recognized. 

Acute  coryza, — In  an  ordinary  cold  in  the  head  the 


prominent  condition  is  the  venous  turgescence.  I  ap- 
plied the  cocaine  in  seven  cases  of  the  affection  and  in 
each  case  the  same  result  was  observed.  The  venous 
sinuses  were  completely  emptied,  and  the  nasal  passages 
remained  absolutely  clear.  The  relief  in  five  of  these 
cases,  which  I  saw  subsequently,  lasted  from  twelve  to 
twenty-four  hours.  That  is,  in  these  cases  the  nose  did 
not  become  "  stopped  up"  again  for  from  twelve  to  twenty- 
four  hours,  and  then  the  relapse  was  only  partial.  The 
colds  were  broken  up.  For  a  cold  in  the  head,  then, 
cocaine,  it  seems  to  me,  promises  to  afford  us  a  remed}', 
which  is  not  only  prompt,  but  certain,  and  by  prescribing 
it  either  in  the  form  of  spray  or  as  a  snuff,  we  can  place  in 
the  hands  of  our  patient  a  ready  means  of  relief  for  that 
most  distressing  symptom  of  a  cold,  the  '*  stopped-up  nose.' 

Nasal  polypus, — ^The  introduction  of  an  instrument 
into  the  nasal  passages  usually  causes  a  swelling  of  the 
membrane  to  such  an  extent  as  to  seriously  interfere 
with  the  inspection  of  the  parts.  In  operating  on  four 
cases  of  polypus  in  the  past  week,  this  troublesome 
feature  of  the  operation  was  entirely  eliminated.  The 
venous  congestion  was  thoroughly  kept  down,  and  so 
clear  a  view  into  the  upper  regions  of  the  nose  was ,  ob- 
tained that  it  was  made  a  comparatively  easy  matter  to 
recognize  and  remove  even  the  smallest  growths.  But 
of  still  further  importance  was  the  fact  that  in  no  case 
was  there  other  than  the  most  trivial  bleeding.  In  re- 
moving nasal  polypi  with  the  snare  the  troublesome 
bleeding  is  never  from  the  mucous  membrane,  but  from 
the  venous  sinuses  which  may  be  opened.  In  the  four 
cases  above  mentioned,  these  sinuses  were  rigidly  con- 
tracted by  the  cocaine,  and  hence  the  bleeding  from  the 
operations  was  but  a  trivial  matter.  ' 

Hay  fever. — ^The  morbid  condition  of  the  nasal  pas- 
sages in  an  exacerbation  of  this  disease  is  undoubtedly  a 
turgescence  of  the  venous  sinuses,  probably  fi-om  a  paresis  of 
the  vaso-motor  nerves  which  are  distributed  to  the  coats  of 
these  vessels.  I  have  had  no  opportunities  of  observing 
the  action  of  cocaine  in  an  acute  exacerbation  of  hay 
fever,  but  I  have  applied  it  in  two  cases  in  which  the 
symptoms  were  present  to  a  mild  extent.  Both  were 
cases  of  autumnal  catarrh,  commencing  August  26th  and 
lasting  till  the  first  frost.  In  each  of  these  cases  the  re- 
sult was  the  same.  There  was  complete  relief  from  all 
the  symptoms. 

The  above-mentioned  cases  may  not,  perhaps,  be  con- 
clusive as  regards  this  action  of  the  cocaine,  but  it  cer- 
tainly goes  very  far  toward  establishing  its  value.  I  used 
it  in  forty  cases,  all  presenting  marked  swelling  of  the 
nasal  mucous  membrane,  both  from  chronic  and  acute 
causes,  and  in  every  case  the  result  was  the  same.  There 
was  an  absolute  and  complete  subsidence  of  the  turges- 
cence of  the  membrane  and  the  sinuses  were  entirely 
emptied  of  their  blood. 

Among  the  observed  symptoms  of  the  internal  admin- 
istration of  cocaine  is  the  production  of  tetanic  muscular 
contraction.  The  only  explanation  of  its  above  observed 
action  is  that  it  produces  the  same  action  upon  the  mus- 
cular fibres  which  are  found  surrounding  the  venous 
sinuses  which  form  the  erectile  tissue  of  the  nose.  Its 
action,  it  should  be  mentioned,  is  confined  to  the  venous 
sinuses,  for  I  have  never  observed  that  it  exerted  any 
influence  upon  the  capillary  circulation  of  the  mucous 
membrane  of  any  region.  A  tetanic  contraction  of  the 
muscular  fibres  which  surround  the  venous  sinuses  in  the 
nose  could  only  produce  the  condition  I  have  observed, 


534 


THE  MEDICAL  JIECORD. 


[November 


n 

t5»  1884. 


for  when  the  cocaine  has  had  time  to  .exert  its  action, 
the  mucous  membrane  is  seen  to  cling  to  the  turbinated 
bones  with  a  rigid  clasp  which  can  only  be  described  as 
tetanic. 

While,  then,  we  have  in  the  cocaine  a  local  anaes- 
thetic of  very  great  value,  I  think  we  also  have  a  thera- 
peutic agent  of  inestimable  importance,  and  which  we 
have  every  reason  to  believe  will  be  efficient,  i,  to  con- 
trol the  exacerbation  of  hay  fever ;  2,  to  relieve  the  most 
distressing  symptoms  of  an  acute  coryza  and  curtail  its 
duration  ;  3,  to  control  the  painful  and  distressing  reac- 
tion which  results  from  the  use  of  caustics  or  instruments 
in  the  'nasal  cavity  ;  4,  to  completely  empty  the  venous 
sinuses  of^the  nasal  mucous  membrane,  and  thereby 
afford  a  thorough  ocular  inspection  of  the  cavities ;  5,  to 
largely  eliminate  from  our  minor  operations  in  the  nasal 
cavities  the  troublesome  hemorrhage  which  so  often  oc- 
curs, and  to  control  epistaxis  from  whatever  cause. 


SOME   NOTES   ON  HYDROCHLORATE   OF 

COCAINE. 

By  N.  J.  HEPBURN,  M.D., 

OPHTHALMOLOGIST  TO  THE  DKMILT  DISPBNSASY,    NKW  YORK,  KTC. 

In  the  course  of  some  experimental  inquiries  into  the 
anaesthetic  action  of  hydrochlorate  of  cocoaine,  I  ob- 
served some  facts  which  may  be  of  interest  at  this  time. 

A  two  per  cent,  solution  of  the  salt  (Merck's)  was 
used  in  each  instance,  injected  under  the  skin  of  the  arm 
by  means  of  a  hard-rubber  hypodermic  syringe  with 
gilded  steel  needle. 

On  October  16,  1884,  I  injected  six  minims  of  the 
solution  at  7.30  a«m.  In  one  minute  and  a  half  there 
was  partial  anaesthesia  of  the  skin  and  subcutaneous  cel- 
lular tissue  for  a  space  of  eight  lines  in  every  direction 
from  the  centre  of  the  injection.  In  four  minutes  the 
anaesthesia  was  complete  over  the  same  area,  which  was 
bounded  by  a  hypeVassthetic  line  separating  the  anaes- 
thetic portion  from  that  of  normal  sensation.  The  in- 
jection was  repeated  every  five  minutes  in  adjacent  spots 
with  precisely  similar  results,  until  forty-eight  minims  had 
been  used. 

By  this  time  ^the  general  physiological  effects  of  the 
drug  began  to  manifest  themselves  so  plainly  that  it 
was  deemed  unadvisable  to  continue  the  experiment. 
These  effects  were  increased  frequency  of  the  pulse, 
increase  of  one-fourth  in  the  number  of  respirations  per 
minute,  an  agreeable  feeling  of  warmth,  moderate  mydri- 
asis, slightly  crossed  diplopia,  and  agreeable  hallucinations 
with  closed  eyes,  which  fancies  disappeared  when  the 
eyes  were  opened.  The  power  of  locomotion  was  very 
slightly  interifered  with.  These  symptoms  gradually  dis- 
appeared, uiitil,  two  hours  after  the  last  injection,  nothing 
abnormal  was  noticed. 

Two  days  later  another  trial  of  the  same  nature  was 
made,  when  it  was  found  possible  to  carry  the  number 
of  six-minim  injections  to  sixteen  before  the  general  dis- 
turbance became  too  marked  to  continue. 

In  a  third  trial,  October  2 2d,  using  eight  minims  at 
each  injection,  it  took  sixteen  injections  also  to  produce 
the  same  toxic  effect  On  this  trial  the  disturbances 
were  more  marked,  and  continued  at  least  four  hours, 
followed  by  a  period  of  wakefulness  lastinr  nearly  all 
night 

The  most  noticeable  of  the  sensations  observed  at 
this  last  trial  were  a  general  impairment  of  cutaneous 
sensibility,  a  feeling  as  if  walking  on  cushions,  a  tendency 
to  walk  on  the  heels,  and  a  sensation  on  grasping  an  ob- 
ject as  if  something  spongy  were  interposed. 

367  West  Twenty-^hiro  Stkeet. 


Two  Thousand  Dolxars  for  a  Body. — ^The  daily 
papers  mention  a  recent  case  in  one  of  the  Indiana 
courts  where  a  medical  college  was  obliged  to  pay 
$2,000  for  having  robbed  a  grave  to  secure  the  body  for 
dissection.     The  name  of  the  college  is  not  given. 


TRACHEOTOMY  IN    CROUP    AND    DIPH- 
THERIA. 

By  SIMON  BARUCH,  M.D., 


It  is  **9L  healthy  sign  of  the  times"  when  the  discussion 
of  worn  and  tnte  subjects  of  practical  import  occupies 
the  minds  of  our  profession,  and  when  the  search  s&a 
novelties  is  for  the  nonce  in  abeyance.     The  subject  of 
tracheotomy  in  croup  and  diphtheria  has  long  been  the 
theme  of  anxious  and   earnest  inquiry.     Its  literature 
has  grown  to  unwieldy  proportions,  as  is  witnessed  by 
the  fact  that  the  library  of  the  Surgeon-General's  office 
contains   five    hundred  and  eighty-four  separate  trea- 
tises, upon  the   subject  of  tradieotomy  in  croup  and 
diphtheria,  occupying  in  their  enumeration   twelve  and 
one-half  columns  of  the  index  catalogue.     The  paper 
read    recently  upon    this    subject    before  the   Obstet- 
rical Section  of  the  Academy,  by  Dr.  Joseph  Winters, 
presents  an  able,  lucid,  earnest,  and  logical  defence  d 
this  life-saving  operation.     I  am  sure  its  careful  perusal 
will  serve  to  embolden  the  timid  to  advise  and  execute 
the  operation  more  early  and  more  frequently,  and  it  will 
encourage   the   bold  in  pressing  its  advantages  more 
persistently.      I   make   this  small  contribution  to  the 
subject  in  order  to  elicit  from  practitioners  in  all  sections 
of  our  country  an  expression  of  opinion.    It  is  to  be  hoped 
that  the  interest  in  the  subject  will  not  be  allowed  to 
flag,  as  has  so  often  been  the  case  in  its  history,  but 
that  the  practical  tendency  of  the  modem  medical  mind 
will  keep  it  before  the  profession  until  its  true  merits 
are  definitely  ascertained  and  recognized.     It  will  be  the 
most  important  outcome  of  the  present  agitation  of  the 
subject,  if  general  practitioners  who  in  remote  country 
districts  and  smaller  towns  frequently  do  other  siurgical 
work,  can  be  persuaded  that  tracheotomy  is  not  a  ha^d- 
ous  operation,  and  that  as  a  surgical  procedure  it  does 
not  require  extraordinary  skill  or  knowledge. 

It  is  a  sad,  too  sad  fact,  that  precious  time  is  often 
lost  in  the  search  for  a  surgeon;  and  that  at  other 
times  the  procedure  is  regarded  by  parents  in  the  li^t 
of  a  capital  operation,  w£ch  handicaps  their  child  in  its 
struggle  for  life.  These  reasons  operate  in  favor  of  delay 
until  the  operation  becomes  one  of  emergency.  It  is  a 
fact  to  be  remembered,  that  one  successful  tracheotomy 
for  croup  or  diphtheria  will  do  more  to  neutralize  the 
groundless  apprehension,  in  the  minds  of  physicians  and 
la)rmen,  than  all  the  statistics  marshalled  by  high 
authority.  As  an  iUustration  I  will  mention  that  two 
year  ago  Dr.  Abram  Jacobi  performed  a  successful  trache- 
otomy on  a  child  in  Carmansville,  a  suburb  of  this  city, 
and  since  that  time  there  is  rarely  an  objection  made  to 
the  operation.  Within  the  past  six  months  I  have  done 
it  three  times  in  that  section  of  the  city,  and  I  cite  these 
cases  in  order  to  illustrate  the  chief  aim  of  this  paper 
which  is  to  emphasize  the  necessity  for  an  early  opera- 
tion. On  May  21, 1884,  I  was  asked  by  Dr.  William 
Frothingham  to  see  a  boy,  three  years  of  age,  who  had 
been  under  treatment  for  diphtheria  for  several  days  and 
was  rapidly  growing  worse.  The  turpentine  treatment,  so 
much  lauded  in  Germany,  was  advised  and  adopted,  but 
without  avail.  Patient  became  cyanotic,  and  tracheotomy 
was  adopted  as  a  dernier  ressort  By  the  light  of « 
kerosene  lamp,  and  amid  the  wailing  of  parents  and 
friends,  the  gasping  child  was  placed  upon  the  table. 
He  was  so  completely  cyanosed  that  no  anaesthetic  was 
necessary.  When  the  tradiea  was  reached  pulse  and  respi- 
ration ceased.  The  trachea  was  quickly  opened,  the  tube 
inserted,  and  in  a  moment  the  inrush  of  air  brought  on 
cough  and  an  expiratory  effort  The  color  returned  io 
the  face,  and  the  child  revived,  taking  nourishnoent, 
which  he  had  refused  for  many  hours,  because  of  his  in- 
tense preoccupation  with  the  struggle  for  breath.  It  was 
too  late,  however.     The  child  expired  in  twenty  honrs. 

To  the  second  case  I  was  called  by  Dr.  Goodrich  on 
September  10,  1884,    A  boy,  aged  seven,  was  discovered 


Noverober  15,  1884.] 


THE  MEDICAL  RECORD. 


535 


during  the  night  to  be  ill.  When  the  doctor  was  called 
to  him  he  made  a  diagnosis  of  naso-phaiyngeal  and 
laryngeal  diphtheria.  I  saw  him  a  few  hours  later,  and 
confirmed  the  diagnosis.  The  breathing  was  stridulous, 
there  was  episternal  and  abdominal  retraction,  btlt  no 
cyanosis ;  laryngeal  stenosis  was  unquestionable.  Trache- 
otomy was  advised  and  readily  assented  to  by  the  physi- 
cian and  the  father  of  the  child.  Patient  was  etherized 
by  Dr.  W.  T.  Alexander ;  there  was  nothing  unusual  in 
the  operation  except  the  appearance  of  a  great  gush  of 
venous  blood  when  the  trachea  was  opened,  although  the 
wound  was  dry.  The  incision  was  thus  obscured,  but 
by  aid  of  a  finger-nail  it  was  found  and  somewhat  en- 
laiged.  The  tube  was  rapidly  inserted  and  hemorrhage 
stopped  promptly.  This  point  will  be  referred  to  below. 
Patient  received  -^g  gr.  bichloride  mercury  every  two 
hours,  and  10  til.  tr.  ferri,  with  i  gr.  chlor.  potass.,  every 
hour,  besides  nutrients  ad  libitum.  In  eleven  days  he 
was  sufficiently  recovered  to  warrant  the  removal  of  tlie 
tube,  and  he  is  now  in  perfect  health. 

On  October  7th»  I  was  asked  by  Dr.  Goodrich  to  see 
another  boy,  also  aged  seven,  and,  like  the  last  patient, 
in  perfect  health  before  the  attack.  This  child  had, 
however,  been  ill  five  days  without  treatment.  Stridulous 
breathing  alarmed  the  parents,  who  thought  the  child  was 
simply  suffering  from  a  cold.  When  Dr.  Goodrich  was 
called  he  recognized  at  once  the  dangerous  character  of 
the  malady  and  advised  tracheotomy,  to  which  the  parents 
readily  assented,  because  they  were  aware  of  the  success- 
ful issue  of  the  above-mentioned  case.  When  I  saw  this 
patient  he  was  not  cyanosed,  but  there  was  stridulous 
respiration,  and  in  all  respects  the  case  resembled  the 
last  mentioned,  except  in  the  longer  continuance  of  the 
disease.  The  operation  ([under  ether)  was  somewhat 
embarrassed  by  die  deep  situation  of  the  trachea,  a  very 
large  thyroid  gland,  and  the  presence  of  large  veins 
coursing  across  the  line  of  incision.  The  gland  was 
drawn  upward  by  a  blunt  hook,  the  larger  veins  held 
aside,  one  small  vessel  tied,  and  the  trachea  was  now 
reached  without  difficulty.  When  it  was  opened  it  was 
so  filled  with  diphtheritic  deposit  that  the  incision  was 
bloodless  and  the  knife  grated  as  if  passing  through  the 
soft  rind  of  a  melon.  It  is  to  me  a  marvel  how  this  child 
breathed  through  so  narrow  a  channel  without  being 
markedly  cyanosed.  The  tube  was  readily  inserted. 
Patient  revived,  countenance  became  calm  and  bright, 
pulse  more  quiet  and  regular.  But  it  was  too  late ;  he 
died  on  the  following  day  firom  asthenia. 

These  three  cases  show  clearly  the  vast  advantage  of 
an  early  operation.  The  last  two  cases  were  circum- 
stanced precisely  alike,  being  of  the  same  age,  and  in  the 
tame  social  grade,  but  the  one  was  operated  upon  very 
early,  the  other  very  late.  Statistics  have  again  and 
again  demonstrated  the  value  of  an  early  operation; 
common-sense  is  thus  aided  by  experience.  It  is  crim- 
inal to  wait  until  cyanosis  hangs  out  the  danger  signal 
Aphonia,  stridulous  voice,  and  respiration,  the  distended 
nostrils,  the  heaving  chest,  and  appealing  eye  point  un- 
erringly to  the  speedy  advent  of  carbonic  oxide  poisoning. 
The  patient  is  dying  from  asthenia,  and  threatened 
with  carbonic  oxide  poisoning  in  addition.  We  are  pour- 
ing stimulants,  nutrients,  and  tonics  into  his  stomach  with 
a  view  to  avert  or  counteract  asthenia.  So  assiduously 
is  he  "supported,"  that  he  is  often  scarcely  allowed  to 
sleep.  Of  what  avail  are  all  our  "  supporting  measures  " 
when  he  is  slowly  approaching  strangulation,  when  the 
respiratory  passage  is  encroached  upon  more  and  more 
every  moment,  so  that  he  cannot  obtain  sufficient  oxygen 
to  carry  on  the  machinery  of  life  ?  I  take  it  that  oxygen 
is  facile  princeps  among  stimulants  ;  it  is  the  great  life- 
saving  principle,  the  grand  protecting  »gis  against 
disease  and  death.  All  our  energies  in  sanitary  medi- 
cine.are  bent  in  the  direction  of  increasing  the  supply 
of  oxygen  to  our  dwellings,  schools,  prisons,  etc. ;  all 
our  best  efforts  in  the  hygienic  treatment  of  many  of  our 
patients  are  in  the  direction  of  increasing  the  amount  of 


oxygen  in  their  lungs.  Why,  then,  stand  idly  by  when 
in  diphtheria  our  little  patient  is  hour  by  hour  robbed  of 
the  all-important  element  ?  How  absurd  it  is  to  supply 
artificial  stimulants  while  nature's  great  stimulant  and 
sustainet  is  withheld  !  The  patient  prays  for  air,  and  we 
•give  him  milk  and  brandy ;  "  he  asks  for  bread,  and  we 
give  him  a  stone."  It  cannot  be  too  earnestly  urged 
upon  the  practitioner  that  it  is  his  duty  to  watch  as 
anxiously  for,  and  guard  against,  the  oncoming  of  the 
threatening  air  famine  (carbonic  oxide  poisoning)  as  it  is 
to  watch  and  ^uard  against  the  approach  of  the  food 
famine  (asthenia).  Just  as  we  increase  the  stimulants, 
when  the  pulse  flags,  just  in  the  same  measure  should 
we  increase  the  oxygen  when  the  respiration  flags.  In- 
deed it  is  an  accepted  axiom  of  physiology  that  man  can 
exist  far  better  with  a  limited  supply  of  food  than  with  a 
limited  supply  of  oxygen.  And  yet  physicians  hesitate 
when  they  clearly  see  the  advent  of  cyanosis  and  conse- 
quent asphyxia  in  these  cases.  He  who  hesitates  is  lost, 
and  will  sadly  regret  his  indecision. 

Especially  is  it  the  duty  of  the  attending  physician  to 
operate  early  on  the  first  indication  of  abiding  laryngeal 
stenosis,  when  he  recognizes  the  fact  that  tracheotomy 
is  really  not  a  dangerous  operation.  From  a  somewhat 
extensive  experience  I  may  be  permitted  to  state  that 
tracheotomy  in  children  is  rarely  followed  by  shock  or 
accompanied  by  hemorrhage,  which  latter  is  readily 
stanched  by  pressure  forceps,  serres-fine^  or  ligatures.  It 
is  an  operation  which  may  be  performed  without  diffi- 
culty by  an  ordinarily  steady  hand  and  cool  head.  Hence 
it  does  not,  in  my  opinion,  as  a  surgical  procedure,  en- 
hance the  patient's  danger,  if  undertaken  early.  When  I 
lived  in  the  South  I  was  often  consulted  for  foreign 
bodies  in  the  air-passage.  These  were  sometimes  grains 
of  Indian  com,  but  most  commonly  they  were  the  seeds 
of  the  watermelon.  This  fruit  is  largely  cultivated  in  the 
section  of  South  Carolina  in  which  I  resided.  The 
country  people  regard  it  as  so  harmless  that  children  of 
very  tender  age  even  are  permitted  to  partake  of  it. 
Every  farmer  has  "  a  patch  of  melons ; "  hence  their  use 
is  universal.  It  is  not  uncommon,  while  riding  through 
a  plantation  in  midsummer,  to  see  a  little  negro  child 
sitting  or  lying  near  a  big  watermelon,  and  with  its  tiny 
hands  digging  out  the  juicy  mass  and  stuffing  it  into  its 
mouth.  The  result  is  tiiat  these  babes,  as  well  as  older 
children,  white  and  colored,  occasionally  "  get  the  seed 
into  the  wrong  throat,"  and  are  brought  to  the  physician. 
The  history  of  such  cases  of  "  croup  "  is  usually  clear. 
Rarely  did  a  summer  pass,  during  my  practice  of  fifteen 
years  in  that  section,  without  one  or  more  cases  of  this 
kind  being  brought  to  me  by  the  parents,;  or  sent  by 
country  practitioners. 

With  the  exception  of  one  case,  the  removal  of  the 
foreign  body  was  always  advised  and  executed.  Under 
chloroform  I  have  never  found  the  operation  presenting 
serious  difficulty ;  the  foreign  body  usually  presents  it- 
self at  the  tracheal  incision,  or  is  expelled  into  the 
room  with  the  strong  expiratory  effort  which  always  fol- 
lows the  latter.  The  wound  is  closed  and  heals  within  a 
week  ;  there  is  usually  no  shock,  no  fever,  and  the  only 
trouble  I  have  encountered  is  a  slight  dysphagia  on 
the  third  and  fourth  days.  I  can  recall  only  one  fatal 
case  of  this  kind,  a  negro  boy,  sixteen  years  of  age,  in 
which  the  nature  of  the  foreign  body  was  unknown  and 
was  not  found.  My  fiiend,  Dr.  T.  T.  Robertson,  of 
Winnsboro,  S.  C.,  has  obtained  quite  a  reputation  as  an 
operator  for  watermelon  and  corn-seeds,  having  done 
tracheotomy  many  times  successfully.  It  cannot  be  de- 
nied that  the  presence  of  a  tube  in  the  trachea  seriously 
complicates  the  case,  but  the  advantage  of  a  new  and 
perfect  air-channel  counterbalances  this  eviL 

The  manual  of  the  operation  differs  somewhat  in  the 
hands  of  different  surgeons,  and  it  is  well  for  the  novice  to 
obtain  all  the  information  he  can  on  the  "  points  "  which 
experienced  operators  give.  It  is  important  to  strike  the 
junction  of  the  stemo-hyoid  muscles,  and  avoid  cutting 


536 


THE  MEDICAL  RECORD. 


[November  15, 1884, 


into  the  muscular  fibres.  If  the  latter  happens,  the  opera- 
tor will  find  it  difficult  to  reach  the  trachea,  and  there 
will  of  necessity  be  a  larger  wound  surface  and  more 
hemorrhage.  To  obviate  this  difficulty  I  invariably  di- 
vide the  cervical  fascia  upon  the  grooved  director,  and 
never  attempt  to  enter  between  the  sternohyoid  muscles 
from  cUfove.  Placing  thumb  and  forefinger  upon  either 
extremity  of  the  sternal  manubrium,  the  median  line  is 
easily  obtained,  the  handle  of  the  scalpel  readily  enters 
between  the  muscles  as  they  lie  separately  attached  to 
the  sternum.  Upward  pressure  with  the  handle  acts  as 
a  wedge  to  separate  them.  The  wound  should  be  as  dry 
as  possible  ere  the  trachea  is  opened,  all  vessels  being 
secured  When  the  incision,  which  should  be  ample 
always,  is  made  into  the  trachea,  the  supreme  moment 
of  the  operation  arrives.  There  is  a  struggle  and  an 
ugly  gurgling  of  air  and  blood,  which  readily  disconcert 
the  novice.  At  this  moment  the  surgeon  should  be  calm, 
and  steadily  press  on  to  the  goal — the  insertion  of  the 
tube.  If  blood  wells  up  from  the  wounded  trachea  or 
from  unseen  veins,  the  operator  should  not  stop  to 
stanch  the  hemorrhage.  The  tube  is  the  best  haemos- 
tatic agent,  and  through  its  unyielding  channel  portions 
of  membrane  and  blood  are  more  readily  expelled  or 
drawn  than  through  the  tracheal  wound,  held  open  by 
retractors.  I  am  sure  that  lives  have  been  lost  in  the 
effort  to  check  the  hemorrhage  here  referred  to,  and  by 
delaying  the  introduction  of  the  tube. 

The  after-treatment  should  be  vigorously  pushed  by 
constitutional  measures  and  local  inhalations  of  moist 
air.  It  is  a  too  common  practice  to  fill  the  room  with 
vapor  and  exclude  the  air.  The  patient  needs  a  moder- 
ately warm  and  moist  atmosphere,  but  he  needs  oxygen 
more. 

43  EAtT  FiFTV-MiNTM  SmBT,  October  24, 1884. 


CEREBRAL    LOCALIZATION— THE    CENTRES 
FOR  VISION. 

By  PHILIP^  ZENNER,   A.M.,  M.D., 

CXMaNNATZ,  O. 

(Continued  fixun  p.  460.) 
SOUL-BLINDNESS. 

When  Munk'  removed  the  central  part  of  the  visual 
area  of  dogs  he  produced  a  condition  which  he  termed 
soul-blindness.  The  animals,  though  evidently  retaining 
the  sense  of  vision,  no  longer  recognized  familiar  objects. 
He  supposed  their  brains  to  have  been  robbed  of  that 
part  in  which  were  stored  up  the  visual  images  gained 
from  past  experience,  and  that  they  were,  therefore,  in 
the  condition  of  new-bom,  who  see  but  do  not  know 
what  they  see. 

A  few  words  of  explanation  are  necessary  to  express 
Munk's  views  more  fully. 

An  image  formed  on  the  retina  makes  an  impression 
upon  the  visual  area  of  the  brain  and  is  perceived.  If, 
at  the  same  time,  the  attention  dwells  upon  this  image 
it  leaves  an  impression  upon  the  brain  which  remains, 
perhaps  permanently.  Now  if  the  object  is  seen  again 
It  is  compared  with  this  retained  visual  image,  and  thus 
recognized  as  seen  before.  This  retained  or  memorized 
visual  image  may  now  be  brought  up  in  the  mind  without 
the  external  presence  of  the  object,  it  may  appear  in  the 
fancy  or  imagination,  or  be  utilized  in  thought 

These  memorized  images  are  probably  received  and 
stored  up  where  the  visual  impressions  themselves  are 
received,  that  is  in  the  visual  areas.  But  Munk  believes 
that  they  are  stored  up  in  the  central  part  of  the  vis- 
ual area,  in  relation  with  the  central  part  of  the  retina, 
and  that  when  this  central  part  is  removed  the  memo- 
rized images  are  lost  also.  He  believes  those  images 
are  usually  stored  up  in  the   central  part  because  for 

*  S«e  leoond  paper. 


memorizing  anything  the  act  of  attention  is  always 
necessary.  Ordinarily  attention  is  only  paid  to  images 
which  fall  upon  the  central  part  of  the  retinae;  there- 
fore,^ according  to  Munk,  memorized  images  are  only 
stored  up  in  the  central  part  of  the  visual  areas. 

Mauthner,*  on  the  other  hand,  believes  that  Munk's 
soul-blindness  is  altogether  due  to  impaired  vision,  that 
his  dogs  do  not  recognize  objects  because  they  do  not 
see  distinctly,  and  that  the  efifects  would  be  altogether 
the  same  whether  the  central  parts  of  the  retinae  or  the 
central  parts  of  the  visual  areas  were  destroyed 

The  difference  between  these  views  should  be  dis- 
tinctly recognized.  Mauthner  also  believes  that  ^e 
retained  visual  images  reside  in  the  cortex,  but  he  be- 
lieves that  the  seat  of  these  images  is  coextensive  with 
vision  itself,  whereas  Munk  believes  that,  while  the 
whole  visual  area  is  devoted  to  vision,  some  images  are 
stored  up,  retained,  or  memorized  in  one  part  of  it,  some 
in  other  parts,  and  that  such  images  may  therefore  be 
lost,  while  the  sense  of  vision  is  retained. 

Were  we  only  concerned  with  conditions  experiment- 
ally produced  in  dogs,  I  would  not  have  dwelt  upon  this 
matter  here,  but  similar  conditions  have,  of  late  years, 
been  observed  in  man,  and  the  subject  has  obtained, 
apart  from  its  great  theoretical  interest,  a  certain  practi- 
cal value. 

SOUL-BLINDNBSS   IN   MAN. 

A  few  years  ago  Furstner  first  reported  such  case& 
Others  of  a  similar  character  have  since  been  recorded 
All  of  them  were  cases  of  general  paralysis.  The  visual 
disturbances  in  every  instance  followed  paralytic  attacks 
(apoplectic  or  epileptic  in  character),  and  disappeared 
again  in  part  or  altogether  within  a  few  days  or  weeks. 
In  some  instances  the  mind  was  so  clouded  that  the  ob- 
servations can  scarcely  be  utilized  for  scientific  purposes; 
in  others  the  mind  was  sufficiently  clear  when  the  obser- 
vations  were  made  to  give  the  latter  an  undoubted  value.* 

A  few  illustrative  cases  will  now  be  given.  In  Furst- 
ner's  first  case,'  after  an  epileptiform  seizure  with  loss  of 
consciousness,  a  right  hemiplegia  of  several  days'  duration 
was  found,  also  a  deviation  of  the  eyes  to  the  left,  which 
was  of  two  weeks'  duration.  A  few  weeks  after  this 
seizure,  when  the  mind  was  completely  clear,  it  was  ob- 
served that  patient  recognized  objects  with  the  left  eye, 
but  did  not  appear  to  see  with  the  right  one.  At  least 
he  did  not  recognize  objects  with  the  latter,  and  objects 
brought  suddenly  before  it  did  not  cause  any  reflex 
movements,  winking,  etc.  At  the  same  time  the  pupils 
responded  to  light  and  the  fundi  oculi  were  normal. 

His  vision  improved,  and  it  was  now  noted  that  when 
he  tried  to  f;rasp  an  object  in  the  hand  of  the  physician 
he  moved  his  head  from  side  to  side,  then  seizing  the  arm 
of  the  physician,  followed  it  until  he  reached  the  hand. 
He  could  not  count  objects  without  touching  them. 
Often  in  attempting  to  touch  objects  he  reached  beyood 
them.  In  counting  small  objects  he  often  overlooked 
some,  or  counted  the  same  one  repeatedly.  In  counting 
he  would  move  his  head  constantly  from  side  to  side.  At 
a  later  period  he  could  recognize  small  letters,  but  if  the 
letters  were  combined  to  form  a  word  he  could  neither 
read  the  word  nor  point  out  the  separate  letters. 

The  patient's  mind  was  quite  clear  and  he  was  re- 
peatedly and  carefully  examined.  It  was  explicitly 
stated  that  there  was  neither  color  blindness,  contraction 
of  the  field  of  vision,  hemianopia,  nor  binocular  diplopisi 

These  visual  disturbances  had  almost  disappeared 
when  the  patient  had  other  paralytic  attacks  and  died 
shortly  afterward.  A  focus  of  softening  was  found  in 
each  occipital  lobe. 

In  a  number  of  cases  FQrstner  observed  similar  visual 
disturbances.     They  always  followed  paralytic  attacks, 

I  Gdiirn  und  Ange,  p.  487. 

*  U  has  been  attempted  to  utiliie  these  cases,  especially  diose  of  Ffintner,  b 
certain  questions  of  localization,  but  diere  are  various  reasons  why  they  do  not  an- 
swer for  this  purpose,  and  that  aspect  will  not  be  considered  here,  j 

i  Axduv  £  Psychiatrie,  viii.,  p.  265. 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


537 


but  usually  disappeared  in  a  much  shorter  time  than  in 
the  above  case.  But  these  peculiar  visual  symptoms  are 
even  more  marked  in  some  cases  reported  by  Stenger.* 
In  Stengel's  cases  both  eyes  were  equally  affected. 
I  will  briefly  relate  the  two  most  interesting  ones. 

In  the  first,  in  whom  there  was  already  a  degree  of 
dementia,  there  occurred  paralytic  attacks  every  four  or 
six  weeks,  with  some  elevations  of  temperature  and  con- 
vulsions, chiefly  on  the  ri^ht  side,  followed  by  transient 
right  hemiplegia.  Following  each  attack  there  were  dis- 
turbances of  speech,  with  a  condition  termed  word -deaf- 
ness, and  the  peculiar  visual  disturbances  we  are  about 
to  mention.  The  patient  could  see  a  chair  which  was  in 
his  way,  but  only  avoided  it  after  having  once  stumbled 
over  it.  Fire  brought  close  to  his  eye  did  not  frighten 
him.  He  touched  it  to  find  out  what  it  was,  and  only 
then  avoided  it.  He  could  see  wine,  but  seemed  not  to 
know  its  use  until  it  was  brought  to  his  lips. 

There  appeared  to  be  no  contraction  of  the  field  of 
vision,  for  objects  brought  from  any  side  were  immediately 
perceived.  Fundi  oculi  were  normal.  The  disturbance 
both  of  speech  and  vision  remained  for  about  ten  days 
when  they  gradually  disappeared,  but  after  each  such 
attack  a  number  of  words  and  visual  images  seemed  to 
be  permanently  lost.  The  post-mortem  examination  re- 
vealed the  diffiise  changes  in  the  brain  commonly  found 
in  general  paralysis. 

In  another  case,  after  a  paralytic  attack  the  patient  rec- 
ognized some  objects  through  the  sense  of  vision,  while 
he  did  not  recognize  others.  Thus,  he  recognized  his 
bed,  fire,  and  bread,  but  not  a  needle,  shoes,  or  his 
clothes.  But  (just  as  in  the  case  of  Munk's  dogs)  he 
learned  to  know  a  needle  by  its  mere  appearance  sifter 
being  taught  what  it  was  by  means  of  other  senses. 

The  last  case  I  shall  mention  is  one  reported  by  Zacher,* 
in  which  a  paralytic  attack  left  the  patient  with  diflftculties 
of  speech,  and  motor  and  sensory  disturbances,  and  the 
same  kind  of  visual  symptoms.  Though  paralytics  gen- 
erally seize  food  very  greedily,  this  patient  left  it  un- 
touched until  put  in  his  mouth.  He  was  very  fond  of 
cigars,  but  he  now  took  one  in  his  hand  and  again  laid  it 
aside,  apparently  not  knowing  its  use.  These  visual  dis- 
turbances were  present  only  a  few  days. 

It  is  by  no  means  easy  to  determine  the  exact  character 
of  the  visual  disturbances  in  the  above-mentioned  and 
similar  cases.  The  difi[iculty  is  increased  by  the  fact  that 
in  all  of  them  there  was  a  degree  of  mental  weakness,  and 
in  some  well-marked  dementia.  It  is  quite  probable  that 
in  all  of  these  instances  there  was  some  impairment  of 
vision,  and  that  impaired  vision  alone  can  produce  some- 
what similar  disturbances  seems  to  be  proven  by  two 
cases  of  Wilbrand.*  In  both  of  these  instances  the  pa- 
tients became  suddenly  unable  to  recognize  objects  about 
them,  their  own  houses,  streets  in  which  they  resided,  etc. 
They  could  not,  therefore,  find  their  way  in  the  streets, 
though  they  continued  to  see.  Both  patients  were  sound 
mentelly,  and  in  each  a  homonymous  lateral  hemianopia 
was  subsequently  found. 

In  the  above  cases,  also,  blindness  or  impaired  vision 
in  parts  of  the  retina  is  very  probable.  In  the  first  case 
of  Farstner  the  manner  of  seizing  an  object,  the  con- 
stantly moving  the  head  from  side  to  side  in  trying  to 
count,  and  overlooking  some  objects  while  counting 
others  repeatedly,  seem  to  point  with  great  certainty  to 
spots  of  retinal  blindness.  It  is  true  that  the  patient  was 
carefully  examined  by  skilled  physicians  and  that  color 
blindness,  hemianopia,  etc.,  were  excluded,  but  slight  dis- 
turbances can  be  overlooked  even  on  careful  examina- 
tion. This  fact  is  well.illustrated  by  a  case  of  Wernicke  *  in 
which  an  eminent  ophthalmologist  could  find  nothing  ab- 
normal, though  relative  scotomas  were  afterward  detected, 
certain  parts  of  the  retina  being  still  sensitive  to  light, 
though  the  acuity  of  vision  in  some  parts  was  diminished. 
But  if  it  could  be  determined  that  in  all  cases  of  so- 


^Archiv  f.  Psychiatric,  adii.,  p.  235. 
'  Udier  Hemianopsie,  pp.  172,  176. 


*  Ibid.,  xiv.,  p.  488. 

*  Gehtmkrankhetten,  ii.,  p.  552. 


called  soul-blindness  there  is  impairment  of  vision,  this 
would  not  necessarily  explain  the  complex  of  symptoms. 
The  condition  may,  nevertheless,  be  found  in  them  which 
Munk  claims  to  be  present  in  his  dogs ;  that  is,  in  addition 
to  a  degree  of  retinal  blindness,  and  quite  independent  of 
the  latter,  a  loss  of  cerebral  visual  images  which  in  itself 
explains  the  symptoms. 

There  is,  in  fact,  much  which  points  toward  the  cor- 
rectness of  such  an  explanation.  In  many  of  these  cases 
there  were  at  the  same  time  disturbances  of  speech,  es- 
pecially that  condition  termed  word-deafness,  where  those 
peculiar  conditions  appear  to  be  positively  determined 
with  reference  to  hearing  whereof  there  is  now  question 
as  to  the  sense  of  vision ;  for,  in  these  instances,  without 
having  lost  the  sense  of  hearing  the  patients  do  not  com- 
prehend what  they  hear. 

It  is  also  a  singular  fact  that  in  almost  all  cases  of 
"  soul-blindness  "  the  left  side  of  the  brain  was  affected, 
which,  as  we  have  been  taught  by  other  clinical  observa- 
tions, seems  to  be  the  seat  of  the  highest  cerebral  func- 
tions. 

The  existence  of  a  condition  termed  word-blindness, 
where  written  and  printed  words  cannot  be  read,  a  con- 
dition not  infrequently  found,  and  also  present  in^  some 
of  the  above  cases,  strengthens  the  belief  that  certain 
visual  images  may  be  lost  while  vision  is  retained.  Yet 
it  must  be  acknowledged  that  what  has  as  yet  been  con- 
tributed is  not  sufficient  to  decide  this  difficult  question, 
and  its  solution  must  be  left,  like  that  of  some  other 
questions  with  which  we*  have  dealt,  to  future  investiga- 
tions. 

DiagtwsU. — We  must  now  consider  the  practical  as- 
pect of  our  subject,  the  value  of  the  visual  disturbances 
of  which  we  have  spoken,  especially  hemianopia,  in  diag- 
nosis. 

When  carefully  sought  for  hemianopia  is  not  infi-e- 
quently  found  in  cerebral  disease,  especially  in  those 
cases  where  the  disease  is  ushered  in  by  an  apoplectic 
attack.  Hughlings  Jackson '  found  hemianopia  in 
quite  a  number  of  cases  of  hemiplegia,  and  Gowers" 
states  that  he  never  fails  to  find  hemianopia  in  hemiple- 
gics  when  he  looks  for  it  at  an  early  period.  But  in  the 
latter  case  this  symptom  has  a  local  significance.  A 
sudden  hemiplegia  is  usually  caused  by  a  cerebral  hemor- 
rhage or  the  plugging  of  a  vessel,  conditions  which  pro- 
duce a  temporary  paralyzing  effect  upon  the  entire  brain, 
or  at  least  upon  one  hemisphere.  Hemianopia  produced 
at  such  a  time  need  not  indicate  any  direct  involvement 
of  the  visual  centres.  In  the  same  way  a  hemorrhage 
in  the  occipital  lobe  may  cause  hemiplegia,  though  this 
part  oT  the  brain  has  no  motor  functions.  It  is  these  dis- 
tant effects,  produced  by  sudden  lesions,  which,  when' not 
properly  estimated,  bring  confusion  into  the  study  of 
cerebral  localization.  The  clinical  manifestations,  hemi- 
plegia, aphasia,  hemianopia,  etc.,  which  are  present  only 
a  short  time  after  an  apoplectic  attack,  are  usually  value- 
less in  assisting  to  localize  lesions.  Only  permanent 
symptoms  have  a  local  significance. 

If,  now,  hemianopia  be  a  permanent  symptom,  it  indi- 
cates that  there  is  a  lesion  of  some  part  of  the  visual 
apparatus,  but  it  gives  us  no  knowledge  of  its  more  exact 
locality.  We  have  learned  that  lesions  of  the  optic 
tracts,  of  the  occipital  lobes,  and  of  the  parts  connecting 
the  two,  may  cause  hemianopia,  and  must  now  seek  for 
other  means  to  determine  more  precisely  the  seat  of 
disease. 

There  are  a  few  special  symptoms  which  may  be  of 
value  for  this  purpose.  The  first  is  the  condition  of  the 
pupils.  Disease  of  the  occipital  lobes  has  no  influence 
on  the  contraction  of  the  pupils.  When  both  occipital 
lobes  are  destroyed,  and  there  is  complete  blindness,  the 
pupils  continue  to  respond  to  light.  But  if  the  blind- 
ness be  of  peripheral  origin,  due  to  degeneration  of  the 
optic   nerves  or  tracts,  the  pupils  cease  to  respond  to 

*  Ophtfa.  Hosp.  Reports,  viii.,  p.  330. 

•  Brit.  Med.  Journal,  November  24,  1877. 


538 


THE   MEDICAL  RECORD. 


[November  15,  1884, 


light  Nevertheless,  in  cases  of  hemianopia  this  differ- 
ence in  reaction  of  the  pupils  is  of  little  consequence, 
because  one-half  of  the  retina  is  still  sensitive,  and  the 
pupil  will  respond,  no  matter  whether  the  injury  to  one- 
half  of  the  visual  apparatus  be  central  or  peripheral.  But 
Wernicke  believes  that,  even  with  these  unfavorable  con- 
ditions, with  proper  care  and  skill  we  can  gain  something 
from  this  symptom.  This  is  to  be  done  through  allowing 
light  to  fall  upon  only  one-half  of  the  retina  by  means  of 
proper  apparatus.  Wernicke  mentions  a  case*  where 
he  censures  himself  for  having  neglected  this  means  of 
arriving  at  a  correct  diagnosis.  The  case  was  one  in 
which  there  was  double  hemianopia,  therefore  complete 
blindness.  The  pupils  responded  to  light,  and  the  diag- 
nosis was,  consequently,  disease  of  both  occipital  lobes. 
The  post-mortem  revealed  disease  of  only  one  occipital 
lobe.  The  second  hemianopia  was  caused  by  the  com- 
pression of  the  optic  tract  of  the  other  side.  Wernicke 
believed  that  he  could  have  arrived  at  a  correct  diag- 
nosis had  he  tested  the  pupils  by  throwing  light  upon 
only  one-half  of  a  retina  at  a  time.  On  account  of  the 
difficulties  and  perhaps  unreliability  of  such  examinations 
we  may  be  permitted  to  believe  that  they  will  never  be 
of  much  practical  value. 

The  ophthalmoscopic  appearance  of  the  optic  disks 
may  also  assist  us  to  distinguish  peripheral  from  central 
disease.  The  object  of  the  examination  is  to  determine 
whether  or  not  there  is  any  atrophy  of  the  optic  nerves. 
Peripheral  disease  is  more  frequently  and  more  quickly 
followed  by  such  atrophy  than  central  disease,  so  that 
the  early  appearance  of  discoloration  of  the  disks  makes 
the  existence  of  peripheral  disease  probable.* 

These  symptoms,  then,  though  they  have  an  absolute 
worth,  are  practically  of  little  value.  As  in  cerebral 
lesions  elsewhere  located  we  must  base  our  diagnosis 
upon  the  history  of  the  case  and  the  whole  complex  of 
symptoms.  The  mention  of  two  cases  will  serve  for 
iUustration. 

The  first,  a  man  sixty-eight  years  of  age,  observing  a 
defect  of  vision  consulted  an  ophthalmologist,  who  found 
a  left  hemianopia.  There  was  no  other  symptom  at  this 
time,  and  the  patient  continued  to  attend  to  his  business 
until  two  weeks  before  I  saw  him,  when  his  wife  sent  for 
the  family  physician,  because  there  seemed  to  be  some 
change  in  his  mental  condition,  loss  of  memory,  etc. 
When  I  saw  him  there  was  complete  blindness  in  the 
left  half  of  the  field  of  vision,  and  the  patient  saw  but  very 
little  in  the  right  half;  there  was  double  hemianopia. 
There  were  no  changes  in  the  fundus  of  the  eye  and  the 
pupils  responded  to  Ught  There  were  no  other  localizing 
cerefbril  symptoms.  His  only  other  were  mental  symp- 
toms. He  was  forgetful  of  recent  occurrences,  more  emo- 
tional than  normally,  and  was  occasionally  confused  as  to 
locality. 

The  diagnosis  was,  degenerative  changes  in  both  oc- 
cipital lobes,  probably  due  to  thrombosis  in  the  pos- 
terior cerebral  arteries.  The  disease  involved  the  visual 
apparatus  of  both  sides.  It  was  not  a  double  peripheral 
lesion,  or  the  pupils  would  not  respond  to  light  It  was 
not  like  the  above  case  of  Wernicke,  in  which  one  lesion 
(a  tumor)  destroyed  one  occipital  lobe  and  compressed 
the  opposite  optic  tract,  because  everything  was  opposed 
to  the  presence  of  an  extensive  lesion  of  this  character. 
The  mental  symptoms  indicated  that  the  cortex  was  affected. 
From  the  fact  that  there  were  so  few  symptoms,  we  may 
judge  that  the  cortex  was  directly  involved  in  the  lesion, 
and  not  indirectly  affected  by  a  large  lesion  in  a  distant 
part. 

All  above  said  only  permits  us  to  conclude  that  one 
occipital  lobe  is  the  seat  of  disease.  It  could  not  be  de- 
nied that  the  hemianopia  of  one  side  might  still  be  due  to 
peripheral  lesion.  But  it  is  probable  that  in  the  latter 
instance  also  the  disease  is  central,  not  peripheral. 

The  second  case,  a  man  sixty-six  years  of  age,  has  had 

*  GehirnkrankheUen,  iL,  p.  335. 


right  hemianopia  since  seven  years  ago.  At  that  time 
he  had  a  sudden  seizure  without  loss  of  consciousness— 
he  cannot  recall  details  at  this  time — after  which  he  was 
confined  to  bed  for  a  month.  He  thinks  that  he  was  not 
paralyzed,  but  inasmuch  as  he  was  confined  to  his  bed  for 
a  month  at  least,  a  hemiparesis  was  probably  present  An 
examination  by  an  ophthalmologist,  made  four  months 
later,  revealed  a  right  hemianopia,  which  did  not  reach 
quite  to  the  point  of  fixation.  There  was  slight  improve- 
ment within  the  next  year ;  the  field  of  vision  of  both 
eyes  became  a  little  larger. 

Some  months  ago  his  vision  again  became  suddenly 
worse,  probably  due  to  an  attack  of  the  sacne  kind  as 
the  first  one.  At  the  present  time  there  is  a  right  hemi- 
anopia  reaching,  apparently,  to  the  point  of  fixation, 
though,  on  account  of  the  restless  condition  of  the  pa- 
tient, its  exact  limits  can  not  be  determined  with  cer- 
tainty. The  pupils  respond  to  light  The  ophthalmo- 
scopic  appearance  is  normal.  There  are  no  other  cerebral 
symptoms,  but  the  patient  says  he  is  able  to  do  far  less 
mental  work  than  before  the  last  attack. 

This  patient  has  valvular  disease.  The  diagnosis  is 
embolism  of  the  leffc  posterior  cerebral  artery.  But  the 
diagnosis  is  only  a  probable  one.  It  is  based  upon  the 
probable  extent  of  lesion,  the  absence  of  other  localizing 
symptoms,  and  the  mental  impairment 

Bernhardt  *  reported  a  number  of  cases  a  few  yean 
ago,  where,  in  addition  to  hemianopia,  there  were  tran- 
sient affection  of  sensation  and  motion,  and  occasional 
unilateral  convulsions  on  the  same  side.  The  clinical 
picture  in  these  cases  suggested  the  presence  of  degener- 
ative changes,  especially  in  the  surface  of  the  brain,  ex- 
tending beyond  the  limit  of  the  occipital  lobes.  They 
remind  us  of  WestphaFs  case,  where  the  autopsy  revealed 
changes  limited  to  the  cortex.' 

It  is  needless  to  speak  further  of  individual  cases.  The 
above  instances  are  sufficient  to  indicate  how  a  diagnosis 
is  arrived  at,  and  they  illustrate  another  fact,  that  the 
diagnosis  is  often  problematical. 

It  may  appear  to  one  who  has  carefully  read  these 
papers  that  the  laborious  and  diligent  application,  and 
the  profound  research  which  have  been  devoted  to  this 
subject,  though  they  have  done  much  to  enrich  scientific 
knowledge,  have  added  little  to  our  powers  of  curing  dis- 
ease and  alleviating  human  suffering.  And,  at  present, 
such  a  view  has  much  to  substantiate  it,  though  the  case 
of  Wernicke  and  Hahn  affords  a  brilliant  illustration  of 
what  can  already  be  done  in  cerebral  surgery.  But  knowl- 
edge of  cerebral  localization  is  of  very  recent  date.  Ad- 
vances are  constantly  being  made,  and  it  is  only  reasonable 
to  believe  that  far  more  exact  diagnoses  will  readily  be 
made  in  the  future.  Therapeutic  appliances  are  also  be- 
coming better  understood  and  more  valuable,  and  espe- 
cially are  radical  surgical  operations  performed  with  a 
degree  of  safety  not  formerly  dreamt  of. 

With  such  favorable  indications  before  us  we  are  not 
over  bold  when  we  venture  to  state  that  the  knowledge 
of  cerebral  localization  will  yet  be  the  source  of  great 
practical  benefits  to  mankind,  that  it  will  ofttimes  enable 
the  physician  to  cure  those  diseases  which  are  of  all  the 
most  appalling,  for  they  not  only  shorten  life  and  entail 
great  suffering,  but  also  threaten  the  affiicted  with  the 
loss  of  reason. 

Trichlorated  Phenol  in  Erysipelas.— -At  a  recent 
meeting  of  the  Surgical  Society  of  St  Petersburg,  Dr. 
Papow  communicated  the  results  of  his  experience  with 
this  form  of  phenol  as  a  local  application  in  erysipelas. 
The  author  reached  the  conclusion  that  the  drug  arrests 
the  development  of,  or  destroys,  the  micro-organisms 
upon  which  the  disease  is  supposed  to  depend.  He  ad- 
vised its  application  in  a  ten-per-cent.  solution,  to  be 
brushed  over  the  diseased  part  and  the  adjacent  skin.— 
Gazette  des  Hopitaux, 


'  Archiv  f.  Psychiatrie,  xiL,  p.  780. 


>  See  third  paper. 


November  15,  18^4*3 — — ^^  -TRE   MEDICAL  RECORD. 


539 


HISTORY  OF  A  CASE  OF  FISTULA  IN  ANO 
ACCOMPANIED  WITH  INCONTINENCE  OF 
URINE  OF  SEVERAL  YEARS'  STANDING. 

By  MORRIS  H.  HENRY,  M.A.,  M.D.,  LL.D., 

<      LATB  SURGBON-IN-CHIEF  OF  TMK  NEW  YORK  STATB  EMIGRANT  HOSPITALS. 

I  BELIEVE  in  the  records  of  clinical  contributions  that 
speak  for  themselves,  written  in  such  a  way  that  they 
need  little  or  no  commentary  to  explain  their  meaning 
or  add  to  their  interest. 

Case. — Mrs.  ,  about  thirty  years  of  age,  mar- 
ried about  ten  years,  in  affluent  circumstances,  has 
children,  is  of  full  habit  and  to  all  outward  appearance 
perfectly  healthy.  I  was  called  to  her  by  the  advice  of 
her  medical  attendant,  at  her  summer  home,  some  dis- 
tance from  New  York,  in  June,  1883.  She  had  been 
under  the  especial  care  of  a  New  York  physician  during 
the  summer  of  1882,  who  made  his  home  at  a  hotel  in 
the  immediate  vicinity  of  her  then  country  residence,  but 
a  short  distance  from  New  York.  His  ** specialty"  was 
diseases  of  women,  and  he  was  selected  to  attend  her  on 
that  account  He  made  what  he  termed  a  "careful  and 
thorough  examination,  and  discovered  an  inflammation 
and  ulceration  of  the  os  and  cervix  uteri,  which  ac- 
counted for  all  her  distress  and  annoyances.''  Her  main 
suffering,  from  her  own  account,  was  an  intensely  irri- 
table condition  of  the  bladder,  constant  desire  to  mic- 
turate, and  severe  pain  in  the  rectum  at  every  foecal 
discharge.  This  had  existed  for  more  than  ten  years. 
She  remained  under  the  care  of  the  g3aiecologist  during 
the  summer  of  188 1  without  deriving  much  benefit.  He 
was  retained  as  her  medical  adviser,  and  was  with  her 
during  her  confinement,  in  the  spring  of  1882,  with  her 
fourth  child.  She  made  a  good  recovery  from  the  birth 
of  the  child,  but  she  still  suffered  from  distress  in  the 
region  of  the  rectum  and  the  unceasing  annoyance  of 
mcontinence  of  urine. 

Such  is  the  history  of  the  case,  in  brief,  afforded  me 
June  26,  1883,  when  I  was  called  to  attend  her.  The 
local  physician  did  all  in  his  power  to  relieve  her  of  pain 
until  my  arrival  She  complained  of  a  severe  and  in- 
tense throbbing  pain  in  the  region  of  the  rectum,  which 
had  been  steadily  increasing  during  the  past  four  days. 
The  incontinence  of  urine  had  increased — she  had,  in 
fact,  no  control  over  the  bladder.  She  had  had  no  pas- 
sage fi-om  the  bowels  for  three  days,  and  was  averse  to 
making  any  effort  from  fear  of  an  increase  of  pain.  The 
recent  death  of  her  father  from  fistula  in  ano  and  perineal 
abscesses  added  to  her  mental  anxiety  and  suffering. 

On  examination  I  found  a  circumscribed,  deep-seated 
inflammation,  about  three  inches  in  diameter,  on  the  left 
side  of  the  rectum,  the  external  border  close  in  and  in- 
volving the  external  sphincter  of  the  rectum.  There  was 
a  little  oozing  firom  the  centre  of  the  inflamed  mass.  I 
made  a  free  incision  and  relieved  her  of  about  four  ounces 
of  pus.  With  the  aid  of  a  Sims  speculum  and  a  probe  I 
discovered  two  fistulous  openings  in  the  rectum,  one  ex- 
tending about  two  inches  upward  from  the  border  of  the 
anus,  and  the  second  not  quite  as  far,  both  communicat- 
ing with  and  terminating  in  the  external  abscess.  By  in- 
serting a  probe  in  each  track  the  figure  V  was  described, 
with  the  pointed  end  in  the  abscess.  In  deference  to 
her  wishes,  owing  to  the  appearance  that  morning  of 
her  menses,  there  was  no  fiirther  surgical  interference 
that  day.  The  wound  was  dressed  with  warm  fomenta- 
tions and  the  bowels  relieved  with  mild  enema.  She 
was  freed  from  the  acute  pain  and  the  incontinence  was 
lessened. 

July  10,  1883,  assisted  by  the  local  physician,  who 
administered  a  little  chloroform,  I  laid  open  the  two 
fistulous  tracks,  cleansed  the  parts  with  a  solution  of 
labarraque,  and  dressed  the  wound  with  iodoform  and 
vaseline.  As  soon  as  she  had  recovered  from  the  effects 
of  the  chloroform — ^about  three  hours  after  the  operation 
—ten  grains  of  quinine  and  half  a  drachm  of  tincture  of 


hyoscyamus  was  administered  A  few  hours  of  refresh- 
ing sleep  soon  followed.  For  the  first  time  in  many 
years  she  was  able  to  retain  her  water  many  hours.  Th^ 
irritable  condition  of  the  bladder  had  ceased.  The 
wound  was  dressed  twice  daily  in  the  usual  manner  to' in- 
duce healing  from  the  lower  surfaces. 

July  17th. — The  wound  had  entirely  healed  within  the 
rectum,  and  a  few  days  later  it  had  done  so  along  its 
whole  course.  There  were  no  more  painful  or  abnormal 
sensations  about  the  rectum.  The  bowels  yielded  to 
gentle  enema,  and  there  was  no  longer  any  incontinence. 
I  heard  from  her  a  few  days  ago — October,  1884.  She 
was  perfectly  well. 

I  have  now  only  to  add  that  I  believe  ,  this  is  not  an 
isolated  case.  I  record  it  with  the  hope  of  attracting  at- 
tention to  diseases  of  the  rectum  as  a  fruitful  source  of 
''diseases  of  the  bladder  and  uterus"  due  to  reflex 
causes.  I  have  no  doubt  there  are  many  persons  suffer- 
ing in  a  similar  manner,  without  identification  of  the  na^ 
ture  of  the  disease  on  the  part  of  medical  attendants. 

I  581  FiTTH  AvBNUR,  NovembcT,  1884. 


NATURAL   SULPHUR-WATERS,  AND  THEIR 
THERAPEUTICAL  APPLICATION. 

By  HOWARD  PINKNEY,  M.D., 

-       NEW    YORK. 

During  two  summers  spent  in  Europe  visiting  a  few 
of  the  most  noted  spas,  my  attention  was  attracted 
to  the  large  proportion  of  Americans  there  seeking 
relief  for  various  ailments.  I  inquired  of  many  why 
they  came  so  far?  also  if  they  had  ever  tested  the 
virtues  of  American  springs  ?  The  usual  answer  was  that 
"they  had  come  by  Ae  advice  of  their  physician,"  and 
that,  with  few  exceptions,  "  they  had  never  visited  for  treat- 
ment any  springs  at  home."  I  have  conversed  with 
many  of  our  eminent  physicians  and  surgeons,  and  find 
that  while  they  are  quite  familiar  with  the  properties  of 
European  medicinal  waters,  they  have  paid  but  little 
attention  to  those  in  this  country.  Dr.  Walton,  in  his 
work  on  the  mineral  springs  of  the  United  States  and 
Canada^  describes  over  one  hundred  and  ninety  sulphur 
springs  in  the  United  States ;  and  Dr.  Glover  describes 
thirty  sulphurous  or  sulphuretted  spas  in  Europe.  In 
comparing  the  analyses  of  these  different  sulphurous 
springs  it  will  be  found  that  all  so-called  springs  contain 
certain  ingredients  in  common,  and  differ  mamly  as  to 
the  proportion  of  these  in^edients  in  each,  and  the 
temperature  of  the  water  as  it  issues  from  the  sources. 
In  order  to  satisfy  myself  as  to  some  of  the  therapeutic 
effects  of  sulphurous  waters,  I  spent  three  months  at 
Sharon  Springs.  While  there  I  had  the  good  fortune  to 
watch  its  effects  in  the  following  diseases,  viz.:  Rheuma- 
tism and  gout,  acute  and  chronic,  eczema,  psoriasis,  naso- 
pharjmged  catarrh,  catarrhal  inflammation  of  the  Eusta- 
chian tube  causing  deafness,  and  one  case  of  hemiplegia. 
In  all  the  cases  of  rheumatism  and  gout  seen  before 
commencing  the  use  of  the  waters,  the  secretions,  viz.: 
urine,  perspiration,  and  saliva,  were  excessively  acid. 
After  taking  the  baths  and  drinking  the  waters  for  a 
week  or  ten  days,  I  found  the  secretions  much  less  acid ; 
after  the  fourth  week  of  their  use,  in  many  cases  little  or 
no  acid  showed  by  the  blue  litmus  paper  test.  In  the 
cases  of  eczema  the  same  result  was  shown.  In  one  of 
two  cases  of  psoriasis  the  eruption  disappeared  entirely 
after  one  course  of  baths.  In  the  other,  who  only  took 
the  baths,  etc.,  for  two  weeks,  no  improvement  was  per- 
ceptible. In  the  case  of  hemiplegia,  where  the  baths 
and  water  were  used  most  faithfully,  I  could  detect  no 
improvement  in  the  paralyzed  parts,  although  the  general 
health  and  appetite  improved. 

As  sulphuretted  hydrogen  gas  is  so  fi-eely  generated  in 
the  bowels  and  expelled  by  the  rectum,  I  at  first  thought 
that  its  introduction  into  the  stomach,  especially  in  cases 


540  . 


THE   MEDICAL   RECOiJ&  *^*--^:TWi^^^^ 


1884. 


of  dyspepsia,  would  be  injurious.  I  therefore  advised 
that  the  water  should  be  first  heated,  in  order  to  throw 
off  the  free  sulphuretted  hydrogen  before  being  drunk ; 
but,  as  many  visitors,  wjio,  for  years,  had  been  in  the 
habit  of  coming  to  Sharon,  informed  me  that,  whenever 
thev  had  dyspepsia  symptoms— especially  acid  stomach 
— ^tney  always  found  relief  by  taking  a  glass  of  the  sul- 
phur-water as  it  came  from  the  spring,  I  could  not  doubt 
their  testimony,  and  the  following  questions  suggested 
themselves  :  Does  sulphur-water  prevent  fermentation 
outside  the  body?  If  so,  does  it  have  the  same  effect  in 
the  stomach  ?  To  solve  the  first  question,  I  made  the 
following  experiment :  Taking  two  glass  test-tubes  of 
equal  size,  I  partly  filled  one  with  sulphur-water  taken 
directly  from  the  spring.  In  the  other  I  placed  an  equal 
amount  of  rain-water.  To  each  I  added  an  equal  amount 
of  ferment,  composed  of  molasses  and  baker's  yeast, 
corked  and  labelled  each,  and  set  them  aside  in  a  warm 
place. 

On  the  following  day,  when  I  examined  them,  I  found 
that  the  cork  in  the  test-tube  containing  the  rain-water 
had  been  forced  out,  and  that  the  fluid  in  the  tube  was 
turbid  and  covered  with  a  luxuriant  growth  of  yeast 
plant.  The  other  tube,  containing  the  ferment  and  sul- 
phur, appeared  the  same  as  when  I  set  it  aside — the 
cork  was  firmly  in  the  tube,  and  no  growth  appeared  on 
the  surface  of  the  liquid.  I  repeated  this  experiment 
with  tank-water,  and  the  water  used  at  the  table  for 
drinking,  with  like  results — the  sulphur-water  always  ar- 
resting ferment3.tion.  I  naturally  came  to  the  conclu- 
sion thai  if  sulphur-water  prevented  fermentation  outside 
of  the  body,  it  might  have  the  same  effect  in  the  stom- 
ach. Now,  if  this  theory  is  correct,  may  not  some 
similar  change  take  place  in  the  blood  of  rheumatic 
and  gouty  patients,  and  account  for,  in  a  measure,  the 
marked  improvement  in  such  cases  from  the  use  of  the 
waters? 

As  I  was  anxious  to  make  some  investigations  as  to 
the  effect  of  sulphur-spray  upon  inflamed  mucous  sur- 
faces, I  had  an  excellent  opportunity  of  doing  so,  and 
also  the  effect  of  breathing  and  inhaling  an  atmosphere 
highly  charged  with  sulphuretted  hydrogen.  In  connec- 
tion with  the  baths  are  three  inhaling-rooms.  In  the 
first  the  sulphur-water  is  converted  into  a  spray  bf  means 
of  compressed  air,  and  so  arranged  that  it  can  be  applied 
directly  to  any  part  of  the  throat  or  nose.  In  the  sec- 
ond room  the  water  is  converted  into  spray  by  steam 
and  completely  fills  the  apartment.  In  the  third  room 
the  water,  as  it  comes  from  the  spring,  is  mechanically 
broken  up  and  the  sulphuretted  hydrogen  set  free  by  a 
series  of  fountains.  The  air  of  this  room  is  constantly 
charged  with  an  excess  of  sulphuretted  hydrogen  and  can 
be  freely  and  safely  inhaled.  All  the  cases  of  catarrhal 
inflammation  that  I  had  an  opportunity  of  watching  re- 
ceived marked  benefit  from  this  mode  of  application. 
The  beneficial  effects  I  think  result  from  the  following 
causes  :  First,  the  steam  spray  softens  and  relaxes  the 
inflamed  mucous  surfaces ;  second,  the  compressed  air 
spray  cleanses  and  stimulates  to  a  healthy  action  the 
surfaces  with  which  it  comes  in  contact;  third,  the 
breathing  of  air  charged  with  sulphuretted  hydrogen  gas 
has  an  anodyne  and  somewhat  narcotic  effect.  Physi- 
cians who  are  in  the  habit  of  using  the  spray  frequently 
have  added  to  the  sulphur  some  medication,  as  benzoic 
and  boracic  acids  ;  some  preparations  of  the  pine,  as  the 
extract  or  oil  made  from  the  needles  or  leaves  of  the 
pine,  such  as  are  used  so  largely  in  Germany  in  similar 
affections.  The  object  that  I  have  in  view  in  writing  the 
above  is,  to  stimulate  a  more  thorough  research  into  the 
medicinal  properties  of  the  almost  numberless  medicated 
springs  in  the  United  States,  thereby  enabling  physicians 
intelligently  to  advise  their  patients  in  regard  to  the 
various  springs,  at  the  same  time  sparing  them  the  many 
inconveniences  of  sea  and  continental  travel,  especially 
should  they  be  lame  or  crippled. 

34  East  Forty-pixst  Stkibt. 


ilep0rtB  at  hospitals. 


ST.  LUKE'S  HOSPITAL,  NEW  YORK. 

Irrigation  of  Stomach  for  Chronic  Gastritis. 

Reported  by  SAMUEL  T.  KING,  M.D.,  House  Physician. 

The  almost  uniform  success  that  has  been  obtained 
during  my  term  of  service  by  irrigation  of  the  stomach, 
or  lavage,  for  chronic  gastritis  (gastric  catarrh),  is  my 
apology  for  publishing  the  results  of  treatment  in  the  fol- 
lowing cases. 

The  method  of  lavage,  as  performed  at  the  hospital,  is 
very  simple.  The  patient  is  instructed  to  take  no  break- 
fast. At  about  10  A.M.  the  stomach-tube  is  introduced 
and  the  stomach  is  washed  out  several  times  by  the  aid 
of  siphonage.  The  apparatus  used  consists,  first,  of  a 
quite  flexible  rubber  tube  from  one-third  to  one-half  an 
inch  in  diameter,  about  twenty-eight  inches  in  length,  one 
end  being  freely  open  and  the  other  closed,  rounded,  and 
with  one  oval  aperture  on  each  side ;  second,  of  an  ordi- 
nary black  rubber  tube  three  feet  long,  attached  by 
means  of  a  short  glass  tube  to  the  stomach-tube  first 
mentioned  ;  third,  a  small  funnel.  The  temperature  of 
the  water  used  varies  from  100°  to  no**  F.  In  two  or 
three  quarts  of  this  water  is  dissolved  a  teaspoonful  of 
borax.  The  amount  of  water  tolerated  is  judged  by  the 
subjective  sensation  of  fulness,  and  it  varies  considerably 
with  each  case.  The  stomach  is  washed  out  until  the 
returning  fluid  becomes  quite  clear,  usually  three  or  four 
washings  proving  sufficient. 

After  introducing  the  tube  a  little  beyond  the  root 
of  the  tongue,  the  patient  is  instructed  to  swallow,  and 
at  the  same  time  the  tube  is  pushed  somewhat  rapidly 
into  the  stomach.  Occasionally  at  the  first  introduction 
there  is  considerable  difficulty  from  retching,  but  by 
proper  manipulation  this  may  be  readily  overcome. 
After  three  or  four  introductions  the  patient  himself  will 
be  able  to  introduce  the  tube. 

The  following  are  abbreviated  reports  of  all  the  cases 
of  chronic  gastritis  which  have  been  treated  by  lavage 
during  the  past  year. 

Case   I.     {Services  of  Drs.  Beverley  Robinson  and 

Francis  P,  Kinnicutt.)—Vioh^x\,  W ,  seventeen  years 

of  age,  native  of  the  United  States,  errand  boy,  was  ad- 
mitted to  the  hospital  November  9,  1883.  Two  years 
before  entrance  he  first  began  to  have  pains  in  abdomen, 
and  soon  after  vomiting  began.  Had  no  hdemateroesi& 
At  time  of  entrance  he  was  in  a  truly  pitiable  condition, 
his  stomach  rejecting  nearly  everything.  He  was  rapidly 
emaciating.  Skilled  treatment  by  drugs  had  failed  to 
relieve  him.  Upon  entrance,  physical  examination  re- 
vealed dilatation  of  the  stomach.  Lavage  was  imme- 
diately commenced,  and  for  the  first  few  days  the  boy 
was  nourished  entirely  by  nutritive  enemata.  On  No- 
vember 2  2d  he  was  placed  upon  small  quantities  of  pan- 
creatized  milk  by  the  mouth,  given  at  short  intervals  ;  and 
from  that  time  his  diet  was  gradually  increased,  with  the 
exception  of  one  interval  of  a  few  days,  when  there  was  a 
return  of  the  vomiting,  until  he  could  eat  any  form  of 
nitrogenous  food,  and,  finally,  any  kind  of  food.  During 
the  treatment  by  lavage  he  was  given  several  drugs  to 
prevent  emesis  and  putrefaction,  but  apparently  without 
any  especial  benefit.  Patient  had  no  more  vomiting 
after  December  2  2d.  The  lavage  was  reduced  to  every 
other  day  January  20,  1884,  and  entirely  discontinued  at 
the  end  of  another  month.  From  January  ist  until  date 
of  discharge,  February  19th,  patient  gained  eighteen 
pounds  in  weight.  From  that  time  to  tilie  present  date, 
October  22d,  there  has  been  no  return  of  gastric  symp- 
toms. 

Case  II.     {Service  of  Dr,  George  G.   Wheelock.y- 

Louisa  H ,  colored,  thirty  (?)  years  of  age,  a  domestic, 

was  admitted  to  the  hospital  March  15,  1884.     For  a 
I  month  previous  to  entrance  patient  had  been  vomiting 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


541 


after  eating  and  had  suffered  ep^astric  pain  and  distress. 
On  entrance  there  was  anorexia  and  rather  persistent 
vomitinfc  and  she  gave  a  distinctly  phthisical  history. 
Physical  examination  revealed  very  slight  pulmonary 
changes.  Having  obtained  no  satisfactory  results  from 
medicinal  treatment,  April  2  2d  the  patient  was  ordered 
lavage  every  day  and  strictly  milk  diet.  The  gastric 
symptoms  were  entirely  relieved,  and  on  April  30th  she 
was  allowed  some  nitrogenous  food.  On  May  loth,  be- 
cause of  some  irregularity  in  diet,  she  again  began  to 
vomit,  and  although  two  or  three  trials  were  afterward 
made  to  confine  her  to  a  restricted  diet,  she  was  unable 
to  restrain  her  appetite  for  forbidden  articles  of  food,  and 
was  therefore  discharged  June  3d,  materially  improved  in 
her  gastric  symptoms. 

Case  III.     {Service  of  Dr.  George  G.  Wheelock.)— 

Catharine  T ^  forty-six  years  of  age,  married,  a  cook, 

was  admitted  to  the  hospital  April  15,  1884.  She  has 
always  been  a  hearty  eater,  and  occasionally  indulges  in 
malt  liquors.  Three  weeks  before  entrance  she  began 
to  vomit  a  greenish  (bilious  ?)  material,  and  for  the  last 
week  the  vomiting  has  been  persistent  Patient  has 
sour  eructations,  vomiting  of  a  sour  fluid,  and  tenderness 
and  sensitiveness  over  abdomen,  especially  in  epigastric 
region.  Bowels  are  constipated.  Medicinal  treatment 
failing  to  give  relief,  she  was  ordered  lavage  and  milk 
diet.  She  was  discharged  June  nth,  having  entirely  re- 
covered from  her  gastric  symptoms.  May  22d  was  the 
date  of  the  last  vomiting. 

Cask  IV.  {Service  of  Dr.  George  G.  Wheelock.)— 
Geraldine  E ,  colored,  thirty- two  years  of  age,  mar- 
ried, a  domestic,  was  admitted  to  the  hospital  April  28, 
1884.  She  has  had  frequent  vomiting  and  headaches. 
She  often  vomits  large  quantities,  and  at  times  particles 
of  food  which  she  had  eaten  four  or  five  days  previously. 
Upon  entrance,  physical  examination  revealed  marked 
dilatation  of  the  stomach.  Lavage  with  the  usual  precau- 
tions was  ordered,  and  patient  was  discharged  cured 
May  31st.  She  was  seen  during  the  latter  part  of  the 
summer,  and  at  that  time  there  had  been  no  return  of  her 
gastric  symptoms. 

Case  V.     {Service  of  Dr.  Francis  P,  Kinnicutt.)-^ 

Eugene  F- ,  twenty-two  years  of  age,  single,  native 

of  the  United  States,  a  tinsmith,  was  admitted  to  the  hos- 
pital June  25,  1884.  For  the  past  year  he  had  suffered 
from  eructations  of  gas  and  a  sour  fluid  and  constipation, 
and  had  obtained  no  relief  from  skilled  medical  treat- 
ment Has  lost  but  little  flesh  and  strength.  Under 
treatment  by  lavage,  with  pancreatized  milk  as  diet,  his 
^tric  symptoms  were  markedly  improved  but  not  en- 
tirely  relieved. 

Case  VI.  {Service  of  Dr.  A.  Brayton  Ball )— Matilda 
N- ,  thirty-three  years  of  age,  dressmaker,  was  ad- 
mitted to  the  hospital  August  30,  1884.  She  was  suffer- 
ing from  chronic  bronchitis  and  asthma.  She  had  also 
suffered  from  sour  eructations  and  occasional  vomiting 
for  some  time  previous  to  entrance.  Her  cough  ceased 
under  treatment,  but  she  suffered  from  alternating  diar- 
rhoea and  constipation  and  her  gastric  symptoms  per- 
sisted in  spite  of  all  treatment.  September  24th  she  was 
ordered  la  vase  without  change  in  diet,  and  in  the  course 
of  ten  days  she  was  entirely  relieved  from  her  gastric  and 
intestinal  symptoms,  and  has  had  no  return  at  present 
writing,  October  2  2d. 


Salicylic  Acid  in  I-,upus  Vulgaris. — In  a  case  of 
lupus,  in  which  the  disease  had  already  done  much 
damage  to  the  side  of  the  nose,  the  cheeks,  and  the  eve- 
brows.  Dr.  Marshall  {Algem.  Wiener  Med.  Zeii.)  suc- 
ceeded in  healing  the  ulcer  with  salicylic  acid.  He  em- 
ployed an  ointment  containing  3  j.  of  the  acid  to  5j.  of 
vaseline.  The  cicatrix  obtained  was  flexible  and  smooth. 
Altogether  the  result  of  treatment  was  very  gratifying, 
and  the  author  warmly  recommends  the  use  of  the  drug 
in'similar  cases. 


Iodoform  in  Organic  Disease  of  the  Heart. — 
Professor  Testa  {Giornale  diMed.'e  Ter.  di  Messine)  has 
reported  some  observations  made  by  him  on  the  curative 
effect  of  iodoform  in  organic  disease  of  the  heart.  He 
has  studied  the  subject  for  several  years,  and  has  ob- 
served the  effect  of  the  drug  in  a  number  of  cases.  The 
remedy  is  not  directed  against  the  lesions  themselves,  but 
rather  against  the  effects  produced  by  them.  He  ^ves 
the  drug  in  pill  form  every  two  hours,  until  one  grain  is 
taken  during  the  day.  Its  most  marked  effect  is  to 
diminish  the  number  of  heart-beats,  while  it  increases 
the  arterial  tension. 

Calculus  Impacted  in  the  Ureter,  and  the 
Feasibility  of  Removing  it  by  Surgical  Operation, — 
Mr.  Henry  Morris,  Surgeon  to  the  Middlesex  Hospital, 
London,  discusses  {The  American  Journal  of  the  Medical 
Sciences)  the  feasibility  of  removing  from  the  ureter  an 
impacted  calculus,  which,  if  allowed  to  remain,  will 
sooner  or  later  surely  cause  destruction  of  the  kidney,  if 
not  of  life.  He  gives  very  fully  the  clinical  history, 
diagnosis,  and  prognosis  of  these  cases,  and  Anally  urges 
that  a  calculus  impacted  in  the  ureter  sufliciently  near 
the  vesical  orifice  to  be  felt  with  the  finger  can  with  care 
and  suitable  instruments  be  extracted  through  an  incision 
of  the  bladder  wall  without  fear  of  wounding  the  peri- 
toneum, or  laying  open  the  cavity  of  the  bladder.  He 
describes  his  method  of  operating  as  follows :  Having 
rapidly  dilated  the  urethra,  if  the  patient  be  a  female,  or 
opened  the  urethra  in  the  median  line  immediately  in 
front  of  the  prostate,  if  the  patient  be  a  male,  the  neck 
of  the  bladder  should  be  passed  by  the  index  finger  of 
the  left  hand,  and  a  careful  digital  examination  made  of 
the  bladder  walls.  If  a  hard  fixed  body  be  felt  covered 
over  by  the  bladder  mucous  membrane,  at  or  near  the 
orifice  of  one  of  the  ureters,  a  gum  lancet-shaped  knife 
on  a  long  slender  shank  should  be  introduced  along  the 
left  index  finger,  and  with  it  an  incision  should  be  made 
through  the  tissue  covering  the  calculus.  The  knife 
should  then  be  carefully  withdrawn,  and  a  slender  scoop 
or  curette,  introduced  along  the  index  finger  of  the  left 
hand,  still  retained  within  the  bladder,  should  be  employed 
for  gently  turning  the  calculus  out  of  its  bed.  Mr.  Morris 
urges  that  an  exploration  of  the  bladder  should  be  made 
with  the  view  of  performing  this  operation  on  the  ureter 
— I.  In  hydronephrotic  or  pyonephrotic  enlargement  of 
the  kidney,  associated  with  bladder  symptoms,  with  the 
hope  of  re-establishing  the  natural  drainage  through  the 
ureter.  2.  Before  nephrectomy  is  resorted  to  for  hydro- 
nephrotic or  pyonephrotic  tumors,  which  have  been 
opened  or  tapped  through  the  loin  without  benefit.  3. 
Before  nephrectomy  is  resorted  to  in  cases  of  suspected 
renal  calculus  in  which  no  renal  tumor  exists,  and  where, 
after  digital  exploration  and  puncture  of  the  kidney 
through  the  loin,  no  stone  is  found.  4.  In  cases  of 
sudden  or  rapid  suppression  of  urine,  or  anuria,  occur- 
ring after  symptoms  which  have  given  rise  to  suspicion 
of  stone  in  one  or  other  kidney  or  both  kidneys.  A  kid- 
ney which  has  undergone  compensatory  hypertrophy 
may  become  blocked  by  a  calculus  which  has  been  forced 
by  the  superimposed  urine  in  the  lower  end  of  the  ureter, 
and  which  cannot  pass  the  vesical  orifice  of  the  ureter. 
Such  a  kidney  may  be,  probably  is,  the  only  one  the 
patient  has  to  depend  on  ;  and  in  this  case  death  must 
ensue  if  the  obstruction  is  not  removed.  If  no  stone  can 
be  felt  through  the  bladder,  life  may  yet  be  saved  by  giv- 
ing a  vent  to  the  pent-up  urine  by  lumbar  nephrotomy. 

A  Case  of  Imperforate  Rectum  in  which  Lumbar 
Colotomy  was  Performed. — Dr.  John  H.  Packard 
records  a  case  of  imperforate  rectum  in  which  lumbar 
colotomy  was  performed  with  an  unsuccessful  result. 
From  his  experience  he  is  now  of  the  opinion  that  in 
cases  in/which  the  object  is  to  open  the  bowel  with  a 


542 


THE  MEDICAL  RECORD. 


[November  15, 1884. 


view  not  only  to  immediate  relief,  but  to  thp  subsequent 
establishment  of  the  natural  passage  and  closure  of  that 
artificially  made,  inguinal  colotomy  is  the  better  opera- 
tion. His  preference  for  the  operation  in  the  loin  was 
based  upon  a  belief  in  its  greater  safety,  as  well  as  upon 
his  familiarity  with  it  as  practised  upon  the  adult.  But 
the  risk  involved  in  opening  the  peritoneal  cavity,  as 
well  as  the  somewhat  greater  difficulty  of  the  operation, 
would  seem  to  be  outweighed  by  the  advantage  of  far 
readier  access  to  the  cul-de-sac  forming  the  terminal  part 
of  the  gut,  and  by  the  better  prospect  of  thus  remedy- 
ing the  abnormal  condition. — The  American  Journal  of 
the  Medical  Sciences, 

The  Interval  Treatment  of  Bronchitis. — In  The 
London  Practitioner^  September,  1884,  Dr.  Drummond, 
of  Rome,  urges  the  importance  of  treatment  in  those  pa- 
tients who  have  just  \)assed  through  an  attack  of  bron- 
chitis, and  having  no  longer  any  definite  complaints  are 
apt  to  fancy  themselves  in  perfect  health.  He  says  truly 
that  the  leading  points  to  be  observed  in  the  manage- 
ment of  the  various  forms  of  bronchial  inflammation  are, 
as  a  rule,  sufficiently  manifest  and  easy  of  application,  so 
that  when  called  in  to  such  cases  there  is  little  need  for 
hesitation  in  the  choice  of  remedies.  Such  periods  of 
attack  are,  of  course,  especially  at  the  extremes  of  life, 
dmes  of  the  greatest  alarm,  anxiety,  and  pressing  danger 
to  the  patient,  who  is  apt,  however,  to  think  that,  when 
they  have  passed  away,  all  is  well  again,  and  for  this 
reason  we  commonly  lose  sight  of  him  until  another 
seizure  compels  him  again  to  seek  our  aid.  We  know, 
however,  that  this  is  very  far  from  being  the  case  ;  that 
very  often  his  condition  in  the  interval  is  very  critical ; 
that  the  latent  cause,  of  which  the  bronchitis  is  only  a 
secondary  consequence,  is  still  present ;  that  the  interval 
is  the  period  when  really  curative  treatment  is  available, 
and  is  the  most  important  part  of  the  life-history  of  his 
disease.  As  time  goes  on,  if  no  attempt  is  made  to  deal 
with  the  diseased  condition  to  which  the  bronchitis  is 
due,  recurrences  are  more  and  more  frequent ;  and  if  the 
patient  is  still  exposed  to  the  exciting  cause,  especially 
in  a  variable  climate,  they  come  to  be  taken  as  a  mere 
matter  of  course,  and  serve  to  mark  the  winter  exactly 
like  the  return  of  snow  and  fog.  The  patient  is  hardly 
ever  well,  and  becomes  habituated  to  a  condition  of  per- 
manent disablement ;  his  power  of  resistance  to  weather 
changes  is  diminished,  and  a  barometric  sensitiveness  to 
them  is  developed  In  the  background,  steadily  advanc- 
ing, hidden  lesions  lurk ;  and  increasing  emphysema, 
heart  dilation,  lung  collapse,  interstitial  lobular  pneu- 
monia, dilatation  of  the  bronchi,  and  other  changes  pro- 
gress, slowly  but  surely  sapping  the  patient's  strength, 
shortening  the  duration  and^'diminishing  the  enjoyment 
of  life  ;  so  that,  although  chronic  bronchitis  is,  per  se, 
attended  with  comparatively  little  danger  to  life,  it  none 
the  less  originates  or  aggravates  other  lesions,  with  which 
its  clinical  history  is  interwoven,  and  often  in  their  nature 
more  perilous  than  itself.  As  regards  the  nature  of  the 
interval  treatment,  it  must  of  course  vary  in  different 
<:ases,  according  to  the  individuality  of  the  patient. 
General  measures,  proper  hygiene,  and  such  medicines 
as  may  tend  to  improve  the  patient's  constitution  are  all 
indicated,  and  need  not  be  enumerated  here. 

Treatment  of  Malignant  Pustule  by  Cruciform 
Incisions  and  Cauterization. — Dr.  Barberini  writes  to 
the  Rivista  Clinica  e  Terapeutica  for  September,  1884, 
giving  an  account  of  two  cases  of  recovery  from  malig- 
nant pustule.  The  first  case  was  that  of  a  herder,  forty 
years  of  age,  of  fair  general  health.  On  the  left  side  of 
the  lower  lip  there  was  a  small  black  spot,  the  size  of  a 
centime,  slightly  elevated,  and  surrounded  by  an  inflamed 
area,  which  he  said  appeared  the  day  before  as  a  little 
vesicle  exuding  a  little  water  when  scratched.  The  tis- 
sues beneath  the  black  spot  were  v^ry  painful  upon  the 
slightest  touch,  and  the  lymphatics  of  the  part  were 
iswollen  and  cordlike.      The  patient's  temperature  was 


103®  F.  Fifteen  grains  of  sulphate  of  quinine  were  given 
at  once,  and  two  elliptical  incisions  were  made  through 
the  inflamed  zone  at  about  -K  inch  distance  from  the 
blackened  eschar,  the  enclosed  parts  being  excised.  The 
wound  was  then  cauterized  with  strong  carbolic  add 
(eighty-five  percent.).  There  was  but  little  hemorrhage, 
but  the  patient  fell  into  a  state  of  collapse  almost  im- 
mediately.  The  case  seemed  hopeless,  but  quinine  and 
broths  were  prescribed,  and  after  thirty-six  hours  the  pa^ 
tient  began  to  show  signs  of  consciousness  and  progressed 
slowly  to  full  recovery.  The  second  case  was  very 
similar  to  the  first.  The  diagnosis  of  malignant  pustule 
was  undoubted.  The  elliptical  excision  and  cauteriza- 
tion were  practised  as  in  the  first  case,  with  equally  good 
results. 

The  Treatment  of  Hemorrhoids. — Professor  Vei- 
neuil  recommends  cold  local  applications  and  mQd 
laxatives  in  the  treatment  of  slight  cases  of  hemorrhoids. 
For  the  more  severe  cases  he  employs  forced  dilatation. 
Hemorrhoids  are  caused,  he  says,  by  a  strangulation  oC 
the  superior  mesenteric  veins  which  traverse  the  muscular 
wall  of  the  rectum.  This  strangulation  gives  rise  to  the 
formation  of  the  venous  tumors,  precisely  as  varicose 
veins  are  occasioned  by  constriction  from  the  ring  of  the 
soleus  muscle.  If  now  the  muscular  contracture  be 
overcome  the  venous  circulation  is  restored  and  the 
hemorrhoidal  tumors  disappear.  In  order  to  insure  suc- 
cess the  dilatation  should  not  be  attempted  with  the 
fingers,  but  should  be  accomplished  by  means  of  a  spec- 
ulum. By  means  of  this  instrumental  dilatation  the 
author  asserts  that  hemorrhoids  may  be  radically  cored 
within  a  week  without  the  use  of  the  knife. — Revue  Mk- 
dicale^  September  13,  1884. 

Recovery  from  a  Punctured  Wound  of  the 
Heart. — An  old  woman,  sufifering  from  suicidal  mania, 
was  observed  one  evening  to  become  suddenly  pale, 
falling  back  upon  the  bed,  with  the  features  convulsed, 
the  pupils  widely  dilated,  and  the  head  rolling  rhyth- 
mically from  side  to  side.  The  pulse  was  very  small, 
almost  imperceptible,  and  there  was  almost  complete 
paralysis  on  the  left  side  and  paresis  on  the  right.  There 
was  also  vomiting.  On  searching  for  the  cause  it  was 
found  that  the  patient  had  stabbed  herself  with  a  shawl- 
pin.  The  pin  had  entered  the  chest  at  the  apex  of  the 
heart,  and  had  passed  inward,  and  a  little  downward  for 
a  distance  of  three  and  one-fourth  inches.  The  instro- 
ment  was  withdrawn,  and  under  the  influence  of  stimu- 
lants the  heart  recovered  its  normal  action.  For  some 
time  there  was  dyspnoea,  and  the  patient  experienced 
sharp  pains  in  the  precordial  region,  but  at  the  end  of 
ninety  minutes  all  these  symptoms,  as  well  as  the  par- 
alysis, had  disappeared.  The  patient  slept  tranquilly  that 
night,  and  made  a  perfect  recovery. — Gazette  des  Hdpi- 
taux^  No.  100,  1884. 

Colotomy. — A  retrospect  of  the  operation  of  colotomy 
appears  in  the  October  number  of  The  American  Journal  if 
the  Medical  Sciences  from  the  pen  of  Dr.  Batt,  of  Phoenix- 
ville.  Pa.  A  surgeon  who  subscribes  to  the  doctrine  that 
an  artifical  anus  should  not  be  made  in  the  case  of  im- 
perforate anuSy  is  not  justified  in  doing  so  on  any  principle 
of  morality,  since  upon  him  rests  an  imperative  obliga- 
tion to  employ  to  the  utmost  of  his  ability  the  means 
placed  at  his  command  for  the  relief  of  human  suffering 
and  the  prolongation  of  human  life.  When  we  likewise 
consider  of  what  vast  importance  is  the  prolongation  of 
life  in  a  human  adult,  and  how  vast  may  be  the  concerns 
which  hang  upon  such  an  event,  we  find  the  same  imper- 
ative duty  no  less  binding.  To  obviate  death  from 
over-distention  of  the  bowels,  which  is  one  of  the  most 
painful  at)d  distressing  terminations  of  life,  colotomy 
will  be  justifiable  under  conditions  of  the  greatest 
gravity ;  and  may  be  indicated  in  any  obstructive  com- 
plication of  the  lower  bowel  which  has  passed  beyond  the 
power  of  local  remedies,  and  in  which  a  judicious  trial  of 
medical    treatment    has   failed   to    afford   relief.     Mr. 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


543 


Phillips,  of  London,  tells  us  that  one  case  of  intestinal 
obstruction  occurs  in  every  one  hundred  deaths,  and 
from  139  cases  of  obstruction  which  he  collected,  in 
which  surgical  aid  was  not  given,  133  proved  fatal. 
The  fact  that  such  a  terrible  fatality  as  this  should 
exist,  and  an  operation  affording  the  advantages  of 
colotomy  be  unperformed,  must  ever  be  a  shadow  upon 
the  honor  of  modern  surgery.  Statistics  are  presented 
which  show  most  conclusively  that  the  dangers  of  the 
operation  are  very  few,  and  that  the  number  of  recoveries 
depends  very  greatly  upon  the  nature  of  the  affection  for 
which  it  is  performed.  ^ 

The  Prevkntion  of  Hernia  after  Laparotomy. — 
In  a  communication  addressed  to  the  CentrcUblatt  fur 
Chirur^iey  No.  35,  1884,  Dr.  Hagen-Torn  writes  that  in  a 
recent  ovariotomy  performed  by  him,  the  incision  passed 
accidentally  partly  through  the  rectus  muscle  and  partly 
in  the  linea  alba.  Five  months  later  he  saw  the  patient, 
and  found  that  the  cicatrix  in  the  muscle  was  firm,  but 
that  in  the  linea  alba  had  yielded,  giving  rise  to  a  hernia. 
The  text-books  usually  advise  that  the  incision  be  made 
in  the  linea  alba,  but  the  writer,  basing  his  opinion  upon 
his  experience  in  this  case,  believes  that  the  liability  to 
hernia  after  laparotomy  would  be  averted  were  the  in- 
cision practised  entirely  in  the  rectus  muscle.  He 
thinks,  also,  that  healing  by  first  intention  would  be  fa- 
vored by  reason  of  the  greater  thickness  of  the  muscular 
tissue. 

Stricture  of  the  CEsophagus  from  Muscular  Hy- 
pertrophy.— Dr.  Ruppert  relates  in  the  Gazeta  Lekarska^ 
No.  17,  1884,  the  case  of  a  young  man  who  suffered  from 
a  gradually  increasing  stricture  of  the  oesophagus.  A  di- 
agnosis of  carcinoma  was  made,  and  gastrotomy  was  ad- 
vised. The  patient  refused  to  submit  to  the  operation, 
;ind  died  of  starvation.  At  the  autopsy  it  was  found  that 
the  stricture  was  caused  entirely  by  hypertrophied  muscu- 
lar tissue.  The  most  careful  microscopical  examination 
failed  to  discover  any  trace  of  cancer,  the  thickened 
oesophageal  walls  consisting  of  connective  tissue  and 
muscular  fibres  in  a  state  of  fatty  degeneration. 

Resorcin  in  Laryngeal  Affections. — Dr.  J.  An- 
deer  speaks  very  highly  of  the  value  of  resorcin  in  the 
treatment  of  affections  of  the  larynx.  He  says  that  this 
remedy  has  not  only  the  advantage  of  thoroughly  disinfect- 
ing instruments  without  rusting  them,  but  it  also  possesses 
the  valuable  property  of  producing  anaesthesia  of  the  parts 
with  which  it  comes  in  contact.  A  weak  solution  acts 
as  an  astringent,  a  concentrated  one  as  a  caustic,  with 
this  peculiarity,  however,  that  it  never  occasions  cica- 
trices, but  simply  promotes  the  growth  of  new  epithelium. 
This  renders  it  specially  applicable  to  the  treatment  of 
ulcerations  of  the  mucous  membrane.  The  author  states 
that  really  surprising  results  are  obtained  by  the  use  of 
resorcin  in  hyperplasias,  in  aphonia  of  long  duration, 
and  in  other  laryngeal  diseases.  In  tubercular  ulcer- 
ations it  serves  to  moderate  the  cough  and  quiet  the 
pain. — Revue  Mensuelle  de  Laryngologie^  (TOiologie  et 
de  RhinologUy  September,  1884. 

Aphasia  from  I^^digestion. — Several  cases  of  reflex 
nervous  troubles,  caused  by  digestive  disturbances  in 
children,  are  related  in  the  Journal  de  Medecine  et  de 
Chirurgie  Pratiques  for  September,  1884.  A  little  girl, 
three  years  old,  lost  all  power  of  speech,  or  even  of 
making  a  sound  beyond  an  exclamation  of  pain  when 
pinched.  This  state  continued  for  two  hours,  but  ceased 
immediately  upon  an  attack  of  vomiting,  in  which  a  quan- 
tity of  food  and  several  unbroken  cherries  were  thrown 
off.  A  little  boy  was  seized  during  the  night  with  an 
attack  of  acute  indigestion,  and  the  next  morning  was 
aphasic  and  in  a  soporific  condition.  He  slowly  recov- 
ered the  power  of  articulation  toward  the  end  of  that  day. 
In  another  case  a  young  girl  of  nine  years  was  suddenly 
seized  with  heat  of  the  head  and  flushings,  alternating 
with  pallor  of  the  face.     Then  she  became  aphasic,  but 


recovered  the  power  of  speech  in  about  an  hour  after 
having  vomited  undigested  the  meal  taken  the  evening 
previous.  Fraenkel  has  observed  a  case  of  hemiplegia 
due  to  indigestion.  A  |irl,  four  years  of  age,  was  seized 
during  dinner  with  vomiting  and  complete  loss  of  con- 
sciousness. The  physician  thought  that  the  case  was 
one  of  alcoholic  poisoning,  although  the  mother  affirmed 
that  the  child  had  taken  but  a  very  small  quantity  of 
wine.  In  about  half  an  hour  consciousness  returned,  and 
then  it  was  seen  that  the  right  upper  and  lower  extremi- 
ties were  paralyzed,  both  motion  and  sensibility  being 
lost.  This  disappeared  gradually,  and  the  following 
morning  the  child  was  perfectly  well. 

Oleate  of  Chloral  Compound  in  Pruritus. — A 
recent  writer  (St.  Louis  Medical  Journal)  has  had  an 
oleate  of  chloral  made,  which  he  claims  to  have  used 
with  much  success  in  pruritus  anus,  eczema,  and  other 
affections  associated  with  much  itching.  The  compound 
consists  of  one  drachm  each  of  camphor  and  chloral 
and  one  ounce  of  oleic  acid,  thoroughly  mixed  together. 
Camphor  and  chloral  in  equal  parts,  forming  a  liquid,  has 
long  been  known  as  a  vsduable  remedy  in  cases  where 
local  anaesthesia  of  the  cutaneous  nerves  is  desired,  and 
has  been  employed  in  neuralgias  and  pruritus.  The 
addition  of  the  oleic  acid  will  undoubtedly  increase  the 
penetrating  power  of  the  mixture.  It  may  thus  be  found 
useful  in  allaying  the  itching,  while  other  means  are  em- 
ployed to^ecure  permanent  relief. 

Treatment  of  True  Pneumonia  by  the  Cold  Bath. 
— Two  communications  have  been  recently  sent  to  the 
Gazette  des  Hopitaux  by  Dr.  Chauroier,  in  which  he 
strongly  condemns  the  old  treatment  of  pneumonia  by 
drugs,  blisters,  emetics,  and  bleeding.  The  author  claims 
that  statistics  prove  pneumonia  to  be  more  curable  with- 
out drugs  than  with  them,  and  that  children  always 
recover  from  pneumonia  when  drugs  are  withheld.  He 
used  the  cold-bath  treatment  in  fourteen  children,  all  of 
whom  recovered.  His  observations  lead  him  to  conclude 
that  there  is  no  danger  from  the  bath  in  any  stage  of  the 
disease.  He  gives  a  bath  of  ten  minutes'  duration,  at 
from  82°  to  90°,  ^^^ry  two  or  three  hours  to  an  adult, 
and  two  or  three  times  a  day  to  a  child.  Each  bath  pro- 
duces a  lowering  of  the  temperature  of  from  two  to  three 
degrees,  of  the  pulse  from  ten  to  thirty-two  beats,  and 
of  the  respiration  from  six  to  fourteen  per  minute.  The 
bruit  de  souffle  produced  by  the  fever  disappears,  dyf  p- 
noea  is  decreased,  and  there  is  less  thirst.  Tiie  auihor 
is  inclined  to  think  that  mortality  may  be  lessened  by 
the  use  of  the  cold  bath,  although  he  is  ready  to  admit 
that  his  own  observations  concerned  such  cases  only  as 
would  doubtless  have  recovered  without  treatment 

The  Etiology  of  Convulsions  in  Children. — 
Children,  as  is  well  known,  are  far  more  prone  to  convul- 
sions than  grown  persons.  According  to  Dr.  Kjellberg 
(SchmidV s  JahrbiUher\  this  is  due  not  to  any  increased 
irritability  in  the  motor  or  sensory  tracts  or  in  the  reflex 
centres,  but  to  the  fact  that  the  brain  is  unable  to  exer- 
cise any  controlling  influence  upon  the  reflex  centres. 
Convulsions  which  occur  at  the  commencement  or  during 
the  course  of  any  acute  disease  through  direct  central 
irritation  are  symptomatic.  Those  which  are  excited 
reflexly  by  irritation  of  the  sensory  nerve-endings  are 
sympathetic.  Symptomatic  convulsions  are  due  in  part 
to  disturbances  in  the  circulation  and  in  part  to  changes 
in  the  blood.  Among  the  disturbances  in  the  circulation, 
the  most  common  is  a  rapidly  produced  cerebral  ansemia. 
This  may  be  caused  by  hemorrhage,  a  rapid  wiste  of 
the  animal  fluids,  or  arterial  spasm.  In  other  cases  it  is 
due  to  cerebral  compression  or  anatomical  changes  in 
the  brain,  such  as  extravasation  of  blood,  tumors,  soften- 
ing, etc.  Hyperaemia  may  also  cause  convulsions  in- 
directly. When  an  excess  of  blood  is  carried  to  the 
brain  the  cerebro-spinal  fluid  in  the  perivascular  spaces 
cannot  yield,  but  makes  pressure  on  the  smaller  capilla- 
ries, whereby  they  are  emptied  of  their  blood,  and  th*^ 


544 


THE  MEDICAL  RECORD. 


[November  15, 1884. 


real  condition  is  then'  anaemia  of  the  brain.  The  action 
of  venous  stasis  is  very  similar  in  depriving  the  brain  of 
its  necessary  supply  of  arteiial  blood  There  are  often 
changes  in  the  blood  at  the  same  time  with  these  circula- 
tory disturbances.  An  elevated  temperature  is  one  of 
the  most  potent  of  these  causes,  as  by  it  the  irritability  of 
the  nerve-elements  is  increased.  The  quality  of  the 
blood  ma^  be  impaired  also  by  the  introduction  of 
poisons,  either  those  introduced  from  without  or  those 
formed  in  the  tissues  of  the  body  itself.  In  this  category 
belongs  also  the  change  in  the  milk  of  nursing-women 
induced  by  violent  emotion.  Sympathetic  convulsions 
may  be  excited  by  almost  any  irritation  of  the  sensory 
nerve-endings,  in  consequence  either  of  increased  irrita- 
bility of  the  nerves  or  of  diminished  power  of  the  reflex 
controlling  centres.  In  regard  to  the  presence  of  worms 
in  the  intestinal  canal,  the  author  admits  that  this  may  be 
a  cause  of  convulsions,  but  insists  upon  the  necessity  of 
a  search  for  other  causes,  since  worms  may  be  present 
and  yet  have  nothing  to  do  with  the  convulsions.  He 
believes  also  that  dentition  may  be  of  etiological  impor- 
tance, and  does  not  admit  as  valid  the  objections  of  those 
who  say  that  this  is  a  physiological  process  and  therefore 
incapable  of  producing  morbid  symptoms.  He  does  not 
doubt  the  fact  of  an  hereditary  predisposition  to  convul- 
sions in  certain  families,  but  admits  his  inability  to  ex- 
plain it. 

The  Action  of  Hypnotics  on  the  Cerebral  Cir- 
culation.— Drs.  Bergesio  and  Musso,  having  a  patient 
who  had  lost  a  portion  of  the  calvarium,  were  enabled  to 
make  observations  on  the  circulation  in  the  brain.  They 
confirmed  the  view  that  the  brain  is  anaemic  during  sleep. 
Paraldehyde  gave  the  same  result  as  natural  sleep.  Mor- 
phia and  alcohol  caused  endocranial  congestion.  The 
authors  remark  that  the  hypnotic  effects  of  these  drugs 
do  not  depend  upon  the  changes  they  cause  in  the*blood- 
pressure,  but  upon  some  more  intimate  modification, 
perhaps  of  a  chemical  nature,  of  the  cells  of  the  cerebral 
cortex. — London  Medical  Record,  October  15,  1884. 

Experimental  Diphtheria. — In  a  series  of  experi- 
ments Cohnheim  and  Litten,  by  temporarily  shutting  o£f 
the  blood  supply,  produced  in  the  respective  tissues 
changes  in  many  respects  similar  to  diphtheria.  Necrosis 
by  coagulation  (Weigert)  was  a  constant  result.  Dr. 
Heubner,  following  up  these  researches,  produced  a  local 
diphtheria,  not  by  the  ordinary  method  of  cauterizing  the 
mucous  membrane,  but  by  temporarily  interrupting  the 
blood-current.  His  experiments  were  made  on  the  blad- 
ders of  rabbits,  the  neck  of  the  bladder  being  tightly 
ligatured  with  a  silk  thread  for  two  hours.  On  the  suc- 
ceeding days  the  alterations  produced  on  the  vesical 
mucous  membrane  were  carefully  studied.  On  the  first 
day,  these  alterations  consisted  in  an  intense  hemorrhagic 
oedema  of  the  mucous  membrane,  the  epithelium  being 
raised  and  tumid.  On  the  second  day,  there  was  a  solid 
coagulated  exudation.  On  the  third  day,  true  diphtheritic 
patches  were  found  on  the  mucous  membrane.  Still 
later  was  formed  a  " necrosis  from  coagulation"  of  the 
epithelium,  and  of  the  mucous  and  submucous  tissues. 
Microscopically,  this  deposit,  diphtheritic  membrane^  was 
seen  to  be  morphologically  identical  with  the  deposits 
observed  in  diphtheria,  following  scarlatina,  and  in 
epidemic  dysentery.  This  artificial  diphtheria,  then,  is 
produced  by  the  combination  of  grave  inflammation  with 
necrosis.  That  in  the  diphtheritic  parts  the  circulation 
of  blood  existed,  even  shortly  before  death,  the  author 
was  able  to  demonstrate  by  the  auto-injection  of  the  ves- 
sels, like  that  which  takes  place  in  a  very  conspicuous 
manner  in  artificial  pustular  infection,  in  most  evident 
degree,  by  means  of  the  coloration  of  the  bacilli.  In 
man,  local  croup  may  be  caused  by  spasm  of  the  capil- 
laries of  the  mucous  membrane,  lasting  about  two  hours, 
the  capillaries  then  again  becoming  pervious  to  the  blood. 
Such  a  transitory  interruption  of  the  circulation  may  hap- 
pen even  from  the  pressure  of  a  swollen  tonsil  on  the 


vessel.  The  diphtheria  artificially  produced  by  the  author 
was  not  transmissible  by  inoculation  in  healthy  animals. 
In  the  second  part  of  his  work,  Heubner  seeks  to  estab- 
lish  an  artificial  synthesis  between  local  diphtheria  and 
general  infection.  To  this  end  he  first  inoculated  ani- 
mals in  whom  the  mucous  membrane  was  affected  by 
local  diphtheria,  with  pustular  virus,  and  found  an  exces- 
sive accumulation  of  bacilli  in  the  affected  parts,  but  only 
in  the  interior  of  the  vessels,  and  never  outside  them. 
Afterward  he  inoculated  animals,  which  were  made  to 
contract  a  local  diphtheria,  with  diphtheritic  masses  from 
a  man  affected  by  grave  diphtheria ;  the  animals  pre- 
sented splenic  tumor,  hemorrhage  of  the  serous  mem- 
branes, and  died  after  two  or  three  days  with  symptoms 
of  acute  general  infection.  Microscopic  examination  of 
the  patches  showed  in  the  affected  vessels  of  the  mucous 
membrane  certain  bacilli,  partly  disposed  in  groups,  partly 
distributed  in  diplococci,  partly  as  chains  of  four  links. 
The  same  result  was  obtained  with  inoculation  of  scar- 
latinal diphtheria.  However,  the  author  aflirms  absolutely 
that  the  bacilli  found  do  not  represent  the  diphtheritic 
virus.  If  this  were  so,  ihey  must  have  been  found  also 
in  the  man  in  the  vessels  of  the  affected  mucous  mem- 
brane. That,  however,  the  author  has  never  succeeded 
in  finding,  although  he  has  examined  a  long  series  of  sec- 
tions of  the  uvula.  And  for  general  infection  there  is  no 
need  of  special  diphtheritic  microphytes.  The  author 
recalls  the  researches  made  to  produce  sepsis  by  the 
inoculation  of  the  oral  liquid  of  diflerent  men,  sick  and 
healthy  (Vulpian).  The  micro-organisms  found  in  the 
diphtheritic  masses  of  the  oral  cavity  are  consecutive 
to  the  disease  and  not  vice  versa.  Therefore,  as  the 
author  believes,  the  virus  of  human  diphtheria  has  not 
yet  been  found  to  be  constituted  of  an  organized  material. 

Faradization  in  Obstetric  Practice. — Dr.  Tipiakoff 
describes  the  results  of  faradization  as  used  in  Professoi* 
A.  M.  Makeeff's  obstetric  clinic  in  Moscow  {^VraUh, 
Nos.  24  and  25,  1884).  The  conclusions  at  which  the 
author  arrives  are  these:  i.  The  electric  current  is  a 
powerful  as  well  as  a  simple  and  safe  means  of  inducing 
uterine  contractions ;  hence  it  is  indicated  for  inducing 
abortion  or  premature  labor,  also  in  cases  of  uterine 
atony  dSiApostpartum  hemorrhage.  2.  Since  the  strength 
of  the  uterine  contractions  bears  on  the  rapidity  of  dila- 
tation of  the  OS,  faradization  is  indicated  wherever  a  more 
rapid  dilatation  of  the  os  is  desirable ;  as,  for  instance,  in 
cases  of  hemorrhage  depending  on  placenta  prsevia  or 
accompanying  abortion  with  an  irregular  course.  3.  In 
the  puerperal  period  faradization  favors  a  more  regular 
and  complete  involution  of  the  womb.  4.  In  cases  of 
puerperal  endometritis,  faradization  brings  about  continu- 
ous uniform  uterine  contractions,  and  in  this  way  assists 
the  organ  to  expel  decomposed  lochia;  that  is.  it  pre- 
vents the  possibility  of  self-infection,  and  soothes  the 
paroxysmatic  pain  which  causes  so  great  a  discomfort  to 
the  patient. 

Affections  of  the  Liver  in  Inherfted  Syphius.— 
In  the  Archives  Centrales  de  M^decine  Dr.  Barth^lcmy 
discusses  the  question  of  disease  of  the  liver  in  connec- 
tion with  inherited  syphilis,  by  the  light  of  thirty-two 
cases,  which  he  has  collected  from  Various  sources,  manj 
being  from  English  publications.  From  a  study  of  these 
cases  the  author  has  arrived  at  the  following  conclusions. 
Inherited  syphilis,  like  the  acquired  form,  may  give  rise 
to  four  kinds  of  lesion  of  the  liver:  i,  a  congestive  form; 
2,  diffuse  interstitial  hepatitis ;  a  cirrhosis  rather  hyper- 
trophic than  atrophic  ;  3,  gummata  ;  4,  amyloid  disease. 
Affections  of  the  liver  are  much  more  frequent  than  they 
are  supposed  to  be,  bearing  in  mind  the  number  of  sut* 
jects  of  inherited  syphilis  who  survive.  Judging  from  the 
frequence  of  affections  of  the  liver,  and  from  the  fact  that 
the  cure  or  death  of  the  patient  may  depend  on  whether 
specific  treatment  is  adopted  or  not,  the  author  thinks 
that  the  question  of  inherited  syphilis  should  be  borne  in 
mind  in  every  case  of  hepatic  disease  where  the  cause  is 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


545 


doubtful,  or  the  course  unusual,  either  in  respect  of  the 
age  of  the  patient,  or  in  the  absence  of  a  history  capable 
of  explaining  the  malady.  For,  after  alcoholism  and 
malaria,  inherited  syphilis  is,  in  the  author's  opinion,  the 
most  frequent  cause  of  disease  of  the  liver,  not  only  in 
early  but  in  later  life. 

Hache  on  the  Pathology  op  Cystitis. — Dr.  Hache 
thinks  that  lesions  of  the  bladder  and  irritation  applied 
directly  to  its  wall  and  mucous  membrane  do  not  con- 
stitute a  necessary  and  sufficient  cause  of  cystitis,  except 
in  case  of  vesical  tuberculosis,  or  of  the  presence  of  a 
rough  and  irregularly  shaped  foreign  body.     The  causes 
capable  by  themselves  of  constantly  determining  inflam- 
ination  of  the  bladder  are  very  rare.     Beyond  tubercular 
cystitis,  and  other  forms  of  cystitis  due  to  some  general 
morbid  condition — as,  for  instance,  those  of  rheumatic, 
gouty,  and  infective  nature,  which  are  not  of  frequent  oc- 
currence— there  cannot  be  included  in  the  above  category 
scarcely  any  save  severe  accidental  or  surgical  traumatisms 
of  the  bladder,  and  too  sudden  and  complete  evacuation 
of  this  organ  after  over-distention.    Gonorrhoeal  urethritis 
does  not  often  give  rise  to  cystitis,  except  under  the  in- 
fluence of  some  occasional   cause  or  in  a  predisposed 
subject.      Most  of  the  predisposing  causes  act  quite 
simply  by  determining  a  more  or  less  persistent  conges- 
tion of  the  bladder ;  others  have  a  more  or  less  obscure 
mode  of  action,  although  their  influence  is  very  decided. 
Chief  among  these  predisposing  causes  are  the  tuber- 
cular, rheumatic,  and  gouty  diatheses.     These  predispos- 
ing causes  may  sometimes  become  exciting  causes  by 
increase,   extension,   or  repetition   of  their  action,   or 
through  association  with  that  of  other  causes  of  the  same 
group.     These   latter  causes  are  congestion  and  slight 
inflammation  of  neighboring  organs,  especially  in  the  fe- 
male;  tumors,  calculi,  and  foreign  bodies  in  the  blad- 
der ;  incomplete  retention  of  urine,  with  or  without  dis- 
tention ;  habitual  resistance  to  the  needs  of  micturating, 
and  all  the  causes  of  dysuria  and  functional  over-activity 
of  the  bladder ;  stricture  and  foreign  bodies  in  the  ure- 
thra, hypertrophy  of  the  prostate,  etc.     P'inally,  the  part 
of  exciting  cause  is  more  especially  played  by  sudden 
and  complete  retention,  by  cold,  by  catheterism  or  ex- 
ploration of  the  bladder.     The  latter  cause  can  act  only 
on  a  bladder  predisposed  by  the  presence  of  a  tumor  or 
calculus;    the  other  two  causes  are  more  active,  and 
may  even  by  themselves  suffice  to  excite  an  attack  of 
cystitis.     Dr.  Hache's  study  of  the  pathogeny  of  cystitis 
has  led  him  to  insist  on  the  importance  of  congestion 
and  diathesic  influences,  especially  the  tubercular  diathe- 
sis, and  on  the  relatively  limited  part  played  by  lesions 
of  the  urethra  and  prostate. — Revue  de  Chirurgie. 

Hydrate  of  Therpylene. — This  substance,  which 
has  been  discovered  by  M.  Boursier,  can  be  extracted 
by  distillation  from  the  buds  of  several  sorts  of  pine. 
The  fluid  is  saturated  with  oxygen,  and  contains  a  large 
proportion  of  ozone.  According  to  the  author  (Rev,  de 
Th%rap.  Midico-Chir.^  No.  15,  1884)  it  possesses  very 
marked  antiseptic  and  deodorizing  properties,  and  can 
be  used  for  dressing  wounds  and  for  painting  the  throat 
in  diphtheria.  The  vaporized  fluid  has  a  smell  of  tur- 
pentine, and  is  said  to  be  an  efficient  agent  for  the  dis- 
infection of  rooms. 

Lithotrity  Extraordinary. — Dr.  R.  Cran,  of  Upper 
Luckimpore,  Assam,  states  that  stone  is  not  so  rare  a 
disease  in  Assam  as  Dr.  Partridge  thinks.  He  relates 
the  death  of  a  patient,  **  after  a  most  peculiar  operation, 
which  I  shall  describe  as  showing  the  advanced  state  of 
surgery  to  which  they  have  attained.  The  priest,  having 
placed  the  patient  on  his  back,  raised  well  the  anterior 
wall  of  the  abdomen,  placed  a  stone  on  one  side  of  it, 
and  belabored  the  other  with  a  second  stone,  desisting 
when  the  calculus  was  supposed  to  have  been  crushed. 
The  patient  died  a  few  days  after  the  operation.  This 
was  told  me  by  the  first  man  I  operated  on,** — Indian 
Medical  Journal. 


Experiments  on  the  Supra-renal  Capsule. — M. 
Tizzoni,  the  Italian  pathologist,  has  performed  during 
the  past  year  an  interesting  series  of  experiments  on  the 
supra-renal  body.     In  order  to  avoid  unnecessary  sacri- 
fice of  life,  the  author  studied  the  best  methods  of  remov- 
ing the  supra-renal  capsules  without  damage  to  the  sur- 
rounding structures  and  with  the  infliction  of  the  least 
possible  injury  to  the  system  at  large.     After  having 
made  a  small  incision  in  the  lumbar  region  at  the  level 
of  the  adrenal  body,  the  parenchyma  of  the  capsule  was 
lacerated  and  its  ablation  practised,  strict  antiseptic  pre- 
cautions being  observed.     On  the  right  side  the  neigh- 
boring vena  cava  inferior  rendered  the  operation  of  extir- 
pation difficult.     For  his  experiments  Tizzoni  generally 
made  use  of  rabbits  weighing  only  about  a  kilogramme 
each,  because  in  this  circumstance  the  muscular  mass  of 
the  lumbar  region  was  but  little  developed,  and  so  the 
operation  was  facilitated.    When  the  animals  succumbed 
as  the  result  of  the  operative  procedure,  death  was  not 
due  to   the  nervous  accidents    signalized  bv  Brown- 
S^quard,  but  was  caused  by  subcutaneous  and  intermus- 
cular suppuration  infiltrating  the  neighborhood  of  the 
wound.     The  majority  of  the  animals  which  exhibited 
contracture  of  one  or  other  of  the  front  or  hind  limbs 
recovered,  and  it  was  only  rarely  that  paralysis   and 
death  followed  the  appearance  of  the  spastic  contraction. 
The  necropsy  revealed  in  such  cases  the  presence  of  an 
exudation  about  the  meninges  of  the  spinal  cord  and  a 
softening  of  the  spinal  marrow  without  any  demonstrable 
direct  connection  of  the  lesion  of  the  supra-renal  ca]>sule 
with  that  of  the  nervous  centres.     Outside  these  compli 
cations — which  may  be  regarded  as  quite  exceptional— 
the  operation  was  generdly  followed  by  no  grave  acci- 
dents ;  the  animal,  if  the  etherization  were  not  too  pow- 
erful, gave  signs  of  pain  only  when  the  adrenal  capsule 
was  seized  and  lacerated.     If  this  body,  instead  of  being 
completely  removed,  were  allowed  to  remain  in  the  cav- 
ity of  the  abdomen  (of  course,  after  laceration  of  the 
capsule),  the  healing  was  much  more  rapidly  effected ; 
and  if,  some  days  later,  the  animal  were  killed,  not  a 
trace  of  the  lacerated  parenchyma  of  the  supra-renal 
capsule  could   be    detected ;    complete   absorption   of 
the  essential  elements  apipeared  to  have  taken  place. 
Then,  according  to  Tizzoni,  the  supra-renal  body  is  ab- 
sorbed without  giving  rise  to  any  phenomena  such  as 
might  be  interpreted  to  be  of  the  nature  of  blood-poison- 
ing, so  that  the  adrenal  capsule  contains  no  organic 
poison ;  and  if  by  treating  the  organ  with  various  chemi- 
cal reagents  a  poison  be  obtained,  one  may  affirm  that  it 
is  not  produced  during  life,  and  consequently  the  poison 
must  be  due  to  cadaveric  decomposition.      A  certain 
time  after  the  extirpation  of  the  capsule  there  commences 
to  appear  a  brownish  discoloration  of  the  nose,  as  if  the 
animal  had  been  plunged  in  charcoal  powder  after  having 
drank  some  liquid.    Some  small  blackish  linear  markings 
also  may  be  found  scattered  here  and  there   over  the 
mouth  and  nasal  fossae.     The  mucous  membranes   of 
these  regions  seem  at  first  to  be  intact,  but  at  the  end  of 
some  days  they  become  dotted  with  minute  spots  of  the 
color  of  tobacco ;  the  minute  areas  become  circular  as 
they  enlarge,  and  by  coalescence  a  bronzed  surface  of 
considerable  extent  and  of  a  uniform  tint  is  formed,  and 
reaches  its  maximum  intensity  about  the  sixtieth   day 
after  the  operation  of  removal  or  laceration  of  the  supra- 
renal capsule.   A  remarkable  circumstance  is  mentioned 
by  the  Italian  observer,  which  is  to  the  effect  that  the 
destruction  of  one  capsule  only  brings  about  unilateral 
pigmentation  of  that  side   of  the  body  on  which   the 
operation  was  performed.    Tizzoni  further  states  that  the 
various  elements  of  the  supra-renal  capsule  may  be  recon- 
structed.  He  observed  one  case,  one  hundred  and  forty- 
four  days  after  the  supra-renal  body  had  been  almost  total- 
ly destroyed,  in  which  this  regeneration  had  taken  place. 
He  does  not  seek  to  explain  the  mode  of  production 
of  the  bronzing  which  he  observed. — London  Lancet^ 
September  27,  1884. 


54^ 


THE  MEDICAL  RECORD. 


[November  15,  1884. 


The  Medical  Record 


A  Weekly  journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co.,   Nos.  56  and  58  Ufayette  Place. 

New  York,  November  15,  1884. 

THE  UNITED  STATES  COMMISSIONER  OF 
EDUCATION  ON  MEDICAL  EDUCATION 
AND   PRACTICE. 

The  Report  of  the  Commissioner  of  Education  for  1882- 
83  contains  an  unusually  elaborate  review  of  the  progress 
of  medical  education,  written  in  a  critical  but  at  the  same 
time  candid  and  intelligent  spirit.  The  views  expressed 
and  suggestions  made  are  in  harmony  with  those  which 
have  appeared  in  the  editorial  columns  of  The  Medical 
Record  during  the  past  few  years.  Coming  from  a 
gentleman  like  General  Eaton,  however,  who  has  made 
the  subject  of  education  a  special  study  for  many  years, 
they  have  a  fresh  interest  and  force. 

A  review  of  the  condition  of  medical  education  dur- 
ing and  since  colonial  times  is  given,  and  the  gradual 
evolution  of  the  present  system  of  making  doctors  de- 
scribed. It  is  shown  that  although  we  have  now  vastly 
better  means  of  educating  medical  students  than  for- 
merly, yet  we  are  at  present  suffering  from  the  conse- 
quences of  a  long-continued  and  irrational  freedom  in 
the  matter  of  graduating  and  licensing  medical  men. 

The  old  idea,  that  a  physician  should  be  a  man  of 
learning  and  letters  as  well  as  of  art,  having  been  dissi- 
pated, and  all  but  a  few  restrications  upon  education  and 
licensing  having  ceased  to  exist,  "  the  past  fifteen  years," 
says  the  report,  "  shows  a  very  rapid  increase  in  the  num- 
ber of  medical  schools  and  students." 

"  In  plain  English,"  continues  General  Eaton,  "  the 
time  has  now  come  (the  profession  being  so  crowded  and 
the  increase  of  candidates  for  employment  being  so 
much  greater  in  proportion  than  the  increase  of  popula- 
tion) when  the  medical  student  pays  to  the  medical 
college  money  for  which  he  receives  no  calculable  equiva- 
lent ;  he  asks  for  bread  and  receives  a  stone.  The 
really  capable  graduate  is  jostled,  crowded,  shouted 
down,  and  trampled  upon  by  a  horde  of  unwieldy  behe- 
moths, who  not  only  intercept  most  of  the  work  that  he 
only  is  able  to  do  satisfactorily,  but  who  supplement  their 
scant  incomes  by  arts  and  devices  that  his  nature  and 
training  forbid  him  to  join  in.  Having  overcrowded  all 
other  departments  of  medical  employment,  many  of  these 
physicians  by  the  grace  of  a  diploma  have  lately  taken 
up  the  work  of  opening  and  conducting  medical  colleges, 
much  to  the  wrath  and  confusion  of  the  older  schools, 
who  would  dearly  like  to  retain  their  monopoly  of  over- 
supplying  the  market  with  medical  'spring  chickens.' 
The  position  assumed  by  these  older  schools  is  exqui- 


sitely illogical :  they  do  not  like  to  establish  effectual  en- 
trance  examinations  (which  might  force  some  candidates 
to  defer  the  study  of  anatomy  and  chemistry  until  they 
had  mastered  the  simpler  mysteries  of  reading  and 
writing)  because  they  Ao  not  want  to  limit  the  number 
of  doctors  by  artificial  regulations.  This  phrase,  quoted 
from  a  recent  address  by  a  widely  known  and  much  re- 
spected medical  teacher  and  author,  teaches  us  that 
artificial  regulations  mean  all  rules  or  usages  that  may 
or  can  hinder  any  young  white  man  from  paying  money 
twice  over  for  the  privilege  of  hearing  the  same  course 
of  lectures  during  two  courses  of  instruction.  The  regu- 
lations that  forbid  the  faculty  from  receiving  the  money 
of  a  white  woman  or  that  of  a  black  man,  we  learn  by  in- 
ference, are  not  artificial." 

The  report  begins  with  some  comparative  statistics 
showing  the  number  of  schools  of  medicine,  dentistry, 
and  pharmacy  in  this  country  since  1873. 


1873-    «874. 


1875. 


1876. 


1877. 1  1878. 


1879- 


1880.     1881.11882.^ 


Number  of  in-l  ,  , 

stitutions. . .  I       94;       99       106        xoa       106       106       114       xao       za6<     134 

Number  of  in- {  |  I  I 

structors...    1,148    x,i2X    2,173     i.aox    1,278,  x,337|  x,495    f,66oj  x, 746,  1,946 

Number  of  '  |  ■  |  I  'I 

students  ...   8,68x    9,095  j  9,971   xo,  143  x  1,225  ",830  X3,33i  14,006  14,536  15,151 

Another  valuable  table  shows  the  present  condition  of 
these  same  schools : 


I      I 

'1 


Students. 


Libranes. 


E 


« 

I 


i 


:  s§iiy, 


iSoii 


i!£ 


E  ^  =  1  2  8^     -^  ~ 


Medical  and  surgical : 

Regular 

Eclectic 

Homoeopathic 

Dental 

Pharmaceutical 


801,314110,523 
io|  ioqI  907 
III  i88|  1,309 
iSl  276,  820 
151      68'  1,592, 


85i'3.6i7i40»o57i.o" 

80'    312'   1,400    200 

64;    437   4i530     29 

24     323!  6,084     23 

2|    427,  5^695    263 


Grand  total 1x34,1,946  15, 151' 1,021  5,1 16^57,766  1,526 


Property, 

income,  etc 

11 
III 

'1 

;  from  pn>- 
ive  fundi. 

Ilfl 
!  Hi 

I 


Medical  and  surgical 

Regular 

Eclectic 

Homoeopathic  . . . 

Dental 

Pharmaceutical 

Grand  total. . . . 


o-c 

VTA  U 


< 


11 


$2,713,800  11321,283  l$i8,209  i$456.6c» 

228,600  I  3,000  ! 02.897 

310,000  '        »     '        40.50^ 

87.0001     I     1,568      74.000 

180,2001       6,800  372'     381219 


$3i5i9.6oo  $331,083  $20,149  ;$672,2i6 


Quoting  this  same  "medical  professor  and  author" 
further  in  denunciation  of  the  many  new  and  small  col- 
leges which  are  springing  up  all  over  the  country,  the 
report  adds  :  "  Denunciations  like  the  foregoing  are  of 
little  value,  for  they  accomplish  nothing  ;  when  analyzed 
dispassionately  they  are  reduced  to  complaints  that  newer 
competitors  are  underselling  'the  old  and  well-known 
stands.'  Of  course  the  customers  at  the  cheaper  shops 
will  get  an  article  of  inferior  quality ;  that  also  is  a 
Maw'  of  trade."     We  cannot  agree,  however,  here  with 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


54T 


the  opinion  further  expressed  that  closing  up  the  small 
and  cheap  colleges  would  do  no  good.  It  is  only  true 
that  they  will  not  close  until  there  arises  a  wider  de- 
mand for  the  best  educated  doctors. 

An  account  of  the  courageous  steps  taken  by  a  few  of 
the  leading  medical  colleges  in  enforcing  preliminary 
education,  and  in  adopting  graded  and  longer  courses,  as 
illustrated  by  the  University  of  Pennsylvania  Medical 
School,  Harvard,  the  Chicago  Medical  College,  and  the 
Woman's  Medical  College  of  this  city,  is  then' given. 

The  subject  of  regulating  medical  education  and  prac- 
tice is  one  that  particularly  interests  the  profession  at  the 
present  time.  It  will  receive  with  respect,  therefore,  the 
unbiassed  views  of  the  Commissioner  on  this  subject. 
These  [may  be  stated  in  a  few  words.  The  need  and 
legality  of  some  control  is  admitted,  while  as  to  the  mode 
the  report  says  :  "  The  State  of  Illinois  seems  to  have 
solved  the  problem  of  protecting  the  public  without  as- 
sailing the  right  of  personal  medical  judgment." 

In  conclusion,  the  Commissioner  offers  the  following 
suggestions  as  to  the  best  method  of  regulating  medical 
education,  which  we  submit,  for  the  present,  without 
comment:  **  Every  State  and  Territory,  and  Congress 
for  the  District  of  Columbia,  should  pass  a  law  ordering 
every  school  teaching  medicine  or  surgery  in  any  fashion 
whatever  to  furnish  unquestionable  bonds  or  other  like 
security  for  the  speedy  aqquirement  of  a  fund  amounting 
to'not  less  than  $300,000 ;  the  laws  should  direct  that 
this  sum,  as  fast  as  any  part  of  it  is  collected,  shall  be  in- 
vested in  United  States  bonds  or  productive  real  estate 
or  interest-bearing  loans  on  real  estate  security ;  the  laws 
should  also  prescribe  that  the  corporations  so  endowed 
shall  distribute  the  income  derived  from  such  investment 
equitably  between  at  least  ten  professors ;  that  these  pro- 
fessors shall  teach,  didactically  or  clinically,  at  least  one 
hundred  hours  apiece  in  each  calendar  year,  the  instruc- 
tion by 'each  professor  to  be  progressive  in  subject  and 
character ;  that  no  students  shall  be  admitted  to  these 
courses  of  medical  instruction  before  passing  a  satisfac- 
tory examination  in  the  elements  of  language,  mathe- 
matics, physics,  and  biology ;  that  no  candidates  shall  be 
finally  examined  for  degrees  by  a  State  board  till  they 
have  studied  three  years,  during  each  of  which  they  must 
have  studied  at  least  one-third  of  the  course  of  instruc- 
tion provided  by  the  ten  professors  and  the  thousand 
hours  of  teaching  above  mentioned,  and,  in  addition,  per- 
formed such  an  amount  of  dissecting,  laboratory  work, 
and  hospital  attendance  as  the  faculty  shall  deem  neces- 
•  sary ;  two  or  more  schools  desiring  to  unite  their  forces 
under  the  provisions  of  the  acts  should  be  allowed  to  do 
80,  retaining  one  of  the  charters  and  nariies  ahready  in 
existence  if  they  choose,  but  surrendering  the  others; 
and  all  charters  not  thus  fortified  and  regulated  within 
two  years  after  the  passage  of  the  acts  should  be  declared 
null  and  void." 

MADNESS  AND  CRIME. 

A  YOUNG  man  named  Gilbert  W.  H ,  a  physician's 

SOD,  who  had  been  studying,  or  intending  to  study  medi- 
cine at  Baltimore,  went  off  on  a  debauch  lasting  several 
days.  During  this  time  he  drank  considerable  liquor 
and  performed  a  good  many  acts  of  drunken  folly. 
Finally,  he  wound  up  by  shooting  two  women  in  a  house 


of  ill-fame  in  Baltimore.  He  was  brought  to  trial  for 
murder  in  the  first  degree.  Able  counsel  for  the  defence 
put  in  a  plea  of  insanity.  It  was  shown  that  when  a  boy 
he  was  peculiar,  moody,  solitary  in  his  habits,  and 
seemed  to  go  through  many  of  his  duties  in  an  abstracted, 
and  automatic  manner.  He  was  once  brought  home 
unconscious.  Three  local  physicians,  who  had  known 
him  personally  in  the  town  where  he  lived,  testified  to  his. 
unusual  mental  state,  and  one  of  them  thought  that  he 
was  a  case  of  melancholia. 

Only  one  expert  witness  testified  for  the  defence,  and 
one  for  the  prosecution. 

The  witness  for  the  State  was  Dr.  Gundry,  of  Spring, 
Grove  Asylum.  The  hypothetical  question  put  to  him 
by  the  district  attorney  tells  the  story,  and  was  substan- 
tially as  follows 

Assuming  that  the  party  went  into  the  house  at  & 
o'clock  A.M. ;  went  out  a  few  minutes  after  and  did  not 
return  till  noon.  In  the  meantime  he  had  gone  to  a. 
gunsmith  and  purchased  two  revolvers,  the  gunsmith  at 
the  time  not  noticing  anything  particular  in  his  conduct  or 
appearance.  Assuming,  also,  that  he  went  to  a  drug, 
store  and  called  for  an  ounce  of  prussic  acid,  then  went 
back  to  the  house,  called  for  wine,  threw  it  over  his 
clothes  and  the  clothing  of  his  companions  ;  assuming^ 
that  he  went  into  a  second-story  front-room  up-stairs^. 
and  met  the  two  women  in  company  with  two  others  ;. 
that  he  asked  to  be  left  alone  with  two  of  them.  The- 
others  having  left  him,  that  he  then  locked  the  dooE 
and  demanded  a  diamond  ring  of  one  of  them.  She  re- 
fusing him,  that  he  then  went  to  a  bureau  drawer,  took, 
two  pistols,  went  out  of  the  room,  returned  a  fewt 
minutes  later,  made  a  second  demand,  and  the  party 
still  refusing,  that  he  began  firing,  killed  the  two  women,, 
and  fired  at  a  third  who  came  into  the  room.  After  itr 
was  over  that  he  was  cool  and  collected,  and  said  that 
he  did  the  act  out  of  foolishness. 

Dr.  Gundry  testified  that  the  prisoner  was  sane  andi 
responsible.  Dr.  Wm.  H.  Stokes,  of  Mount  Hope  Hos- 
pital, testified  that  he  was  suffering  from  acute  mania,, 
not  epileptic.  The  jury  brought  in  a  verdict  of  man- 
slaughter, thus  admitting  a  partial  responsibility. 

The  case  is  instructive,  as  again  showing  the  directly 
opposing  views  of  two  equally  experienced  medical  ex- 
perts. It  also  shows  that  the  good  sense  of  twelve  men 
sometimes  brings  trials  to  a  measurably  correct  issue,  de- 
spite the  contradictory  illuminations  of  science,  so-called.. 

There  can  be  no  question  that  H had   never 

possessed  a  perfectly  normal  bram,  and  that  he  was  of 
unsound  mind  at  the  time  of  his  act  The  real  question 
would  be,  therefore,  as  to  whether  his  mental  state  was, 
the  result  of  voluntary  indulgence  in  alcohol  and  ab- 
sinthe, and  as  to  how  much  he  was  responsible  for  his. 
condition.  The  facts  brought  out  by  the  evidence  are 
not  sufficient,  as  reported,  to  allow  of  any  profitable  dis- 
cussion on  this  point.  In  fact,  the  whole  trial  seems. 
to  have  been  hastily  and  superficially  conducted. 


MEDICAL  RHYMES. 
We  are  in  receipt  of  a  collection  of  medical  rhymes,  se- 
lected and  compiled  from  a  variety  of  sources,  by  Dr^ 
Hugo  Erichsen,  of  Detroit.'     It  forms  a  neat  volume  of 

>  Chicago  :  J.  H.  Chambers  &  Co.     2884. 


:548 


THE  MEDICAL  RECORD. 


[November  15,  1884, 


220  pages,  embellished  by  a  number  of  illustrations,  and 
igracefully  chaperoned  by  a  rather  amusing  introduction 
from  the  pen  of  Dr.  Willis  P.  King,  of  Sedalia,  Mo. 

In  France  and  Germany  medical  poems,  both  rhymed 
and  totally  unrhythmical,  are  commonly  endemic,  occa- 
sionally epidemic,  and  always  welcomed  and  encouraged 
by  the  profession.  But  in  our  own  country  the  medical 
muse  has  been  rather  coy  and  timid,  quite  probably  for 
lack  of  persistent  wooing. 

The  collection  before  us  is  a  novelty,  and  a  dangerous 
•one  too.  If  not  speedily  suppressed,  we  seriously  appre- 
hend that  it  will  prove  the  starting-point  of  a  violent  out- 
break of  the  medical  rhyming  disease.  There  is  but  one 
-safeguard  against  the  actual  spread  of  this  threatening 
scourge.  It  is  the  immediate  extermination  of  the  en- 
tire edition  already  published,  with  the  stern  determina- 
'tion  on  the  part  of  an  anxious  profession  to  deal  similarly 
•with  all  succeeding  issues.  Perhaps  the  fell  pestilence 
may  thus  be  nipped  in  the  bud  and  a  national  calamity 
averted.  Let  every  practitioner,  therefore,  be  he  en- 
thusiastic  tyro,  or  the  incarnation  of  accumulated  expe- 
dience and  omniscient  medical  senility  ;  be  he  the  ever- 
,  genial  and  ubiquitous  general  practitioner,  or  the  modest, 
unassuming,  hiding-his-light-under-a-bushel  specialist ;  be 
he  a  staunch  partisan  of  Old-Code  legitimacy  in  punc- 
tilious professional  advertising,  or  a  radical,  revolution- 
ary No-Code  iconoclast ;  be  he  a  sullen,  strictly  scien- 
tific, materia-medical  Nihilist,  or  brought  up  in  the 
•catholic  faith  of  optimistic  polypharmacy;  be  he  merely 
a  mild  and  harmless  bacillophobe  or  a  real  raving,  hope- 
less microbomaniac — why,  there  are  many  kinds  and  va- 
rieties of  doctors  ! — ^let  them  all  agree  and  for  the  nonce 
make  a  combined  attack  against  this  dangerous  produc- 
tion. If  every  man  of  them  will  heroically  grapple  with 
-but  a  single  copy  of  the  evil  book,  the  threatened  visita- 
tion may  yet  fail  to  attain  the  climax  of  a  wide-spread 
and  appalling  professional  disaster.  But  in  order  to  suc- 
•cessfully  wrestle  with  and  eventually  overcome  the  dire 
effects  of  the  "  Medical  Rhymes,"  it  will  be  necessary  to 
resort  to  cunning  prophylaxis.  To  be  forewarned  is 
the  best  policy.  We  recommend,  therefore,  before  at- 
tempting the  perusal  of  this  dangerous  and  vicious 
volume,  the  taking  enough  calabar  to  produce  paralysis 
of  the  muscles  of  laughter.  It  is  in  this  way,  and  in  this 
way  only,  that  fatal  tonic  and  clonic  convulsions  of  the 
-diaphragm  can  be  prevented. 

It  is,  of  course,  out  of  the  question  to  indicate  pre- 
-cisely  the  varied  contents  of  this  novel  collection  of 
medical  rhymes.  So  artfully  and  deceitfully  has  the  com- 
ipilation  been  made,  that  some  earnest  piece  of  tender 
poesy  and  touching  sentiment  is  quite  apt  to  be  im- 
*mediately  followed  by  so  ludicrous  and  mirth-provoking 
a  selection  that  the  sudden  transition  from  soul-stirring 
pathos  to  irresistible  shocks  of  loud  laughter,  is  certain 
no  capsize  the  regulating  vasomotors  of  the  best-balanced 
professional  constitution. 

But  in  all  seriousness,  it  is  a  real  pleasure  to  reflect 
*that  there  are  doctors  in  our  land  who,  besides  the 
ability  to  look  wise  and  prescribe  dinner-pills,  have  a 
•capacity  for  writing  acceptable  verse.  Of  course  we  all 
fknew  long  ago  that  our  honored  Holmes  became  a  greater 
^poet  only  through  having  been  a  great  practitioner,  and 
•that  ten    thousand  verdant   youths  annually  aspire   to 


quickly  become  the  latter,  in  order  that  later  they  may 
have  ample  leisure  to  become  the  former. 

But  what  we  did  not  know,  and  what  we  feel  quite 
happy  to  learn,  is  that  in  all  kinds  of  outof-the-way 
towns  and  villages  there  may  be  found  physicians,  the 
mean  drudgery  of  whose  daily  lives  has  not  chilled  warm 
sympathy  with  struggling,  erring,  ungrateful  humanity; 
and  that  at  least  a  chosen  few  can  find  honest,  noble, 
manful  words  for  expressing  the  true  joy  that  lives  in 
their  souls,  as  well  as  the  bitter  anguish  and  disappoint- 
ments that  sometimes  threaten  to  crush  body  and  soul 
together. 

••  Then  struggle  on,  and  on, 
With  all  the  real  you  can, 
Your  motto,  •  Love  to  God- 
Love  to  your  fellow-man.' " 


PROGRESS  IN  CHOLERA  STUDIES. 

The  newspaper  report  that  Dr.  Koch  had  finally  suc- 
ceeded in  inoculating  rabbits  with  cholera  by  his  comma- 
bacilli  is  not  true.  Dr.  Koch  has  not  yet  succeeded  in 
producing  cholera  in  the  lower  animals  by  means  of  his 
cholera-bacilli,  or  if  he  has,  the  report  has  not  been  made 
public. 

On  the  contrary,  the  investigations  of  the  British 
Cholera  Commissioners,  Drs.  Klein  and  Gibbs,  have  so 
far,  according  to  the  British  Medical  Journal,  tended  to 
confirm  the  view  that  comma-bacilli  are  to  be  found  in 
other  diseases  than  Asiatic  cholera.  Furthermore,  the 
gentlemen  referred  to  have  so  far  found  that  the  bacilli  are 
not  present  in  great  numbers  in  the  intestines  of  those 
who  die  suddenly  of  cholera.  Still  more  important  is  the 
fact  reported  that  the  comma-bacilli  of  cholera  and  of 
other  diseases  develop  in  much  the  same  way,  and  that 
there  is  nothing  specific  in  the  mode  of  growth  of  Koch's 
bacillus. 

Drs.  Finkler  and  Prior,  who  discovered  a  comma- 
bacillus  in  cases  of  cholera  nostras,  are  continuing  their 
researches  in  the  laboratory  of  Professor  Ceci  at  Genoa. 
It  is  quite  well  determined  now  that  their  comma-bacillus 
does  not  develop  in  the  same  way  as  Koch's,  and  that 
it  is  of  a  slightly  different  form. 


SERO-SUBLIMATE  AS  A  SURGICAL  DRESSING. 

In  an  address  delivered  at  the  opening  of  the  London 
Medical  Society  on  October  20th,  Sir  Joseph  Lister  de- 
livered a  striking  address  upon  the  use  of  corrosive  sub- 
limate as  a  surgical  dressing.  After  describing  some' 
recent  unexpected  failures  with  carbolic  acid  and  eucalyp- 
tus, owing  to  the  volatility  of  those  drugs  and  the  un- 
certainty as  to  the  gauze  impregnated  with  them  being 
well  prepared,  he  relates  a  series  of  experiments  which 
he  had  made  with  corrosive  sublimate.  The  great  ob- 
jection to  the  use  of  this  powerful  germicide  was  its 
irritant  properties.  Sir  Joseph,  therefore,  endeavored 
to  obviate  this,  and  he  succeeded  in  doing  so  by  com- 
bining the  sublimate  with  blood-serum.  He  found,  what 
indeed  was  well  known  already,  that  corrosive  sublimate 
forms  with  albumen  an  inert  coagulum  of  albuminate  of 
mercury,  and  that  this  coagulum  was  then  soluble  again 
in  an  excess  of  serum.  The  solution  thus  formed  con- 
tains probably  a  double  albuminate  of  mercury.     At  any 


November  15,  1884.] 


THE  MEDICAL  RECORD, 


549' 


rate,  all  the  germicidal  properties  of  the  sublimate  are 
preserved,  while  the  solution  is  at  the  same  time  per- 
fectly non-irritating,  in  any  strength  in  which  it  would  be 
necessary  to  use  it.  Lister  has  so  far  used  gauze  saturated 
with  a  one  per  cent,  solution.  Experiments  with  a  two 
per  cent,  solution  showed  it  to  be  slightly  irritating. 

He  says  :  "  The  corrosive  sublimate  is  so  intimately 
blended  with  the  serum  that  when  it  dries  no  separation 
of  crystals  takes  place.  Whether  we  use  i  to  100,  i  to 
70, 1  to  50,  or  even  i  to  30  parts  of  blood-serum,  they  are 
perfectly  amalgamated,  and  therefore,  from  a  gauze  like 
that,  no  corrosive  sublimate  can  fly  off.  It  can  be  ma- 
nipulated as  you  please,  and  as  applied  dry  to  the  skin 
it  is  absolutely  unirritating.  If,  however,  such  a  gauze 
is  torn,  it  gives  off  a  dust  which  irritates  the  nostrils.  It 
is  therefore  better  to  cut  it  with  scissors.  Then,  in  the 
next  place,  it  is  unirritating  as  acted  on  by  the  perspira- 
tion. If  water  is  made  to  act  on  sublimated  serum  dried, 
it  does  not  redissolve  it,  as  serum  does,  but  it  renders 
the  mass  opaque,  the  water  being  only  partly  absorbed 
into  it ;  and  the  water  which  remains  unabsorbed  con- 
tains exceedingly  little  of  the  corrosive  sublimate,  which 
is  almost  all  retained  by  the  albumen.  Hence,  when 
perspiration  soaks  into  such  a  dressing,  though  it  moistens 
it,  it  does  not  produce  irritation.'' 

The  use  of  this  sero-sublimate  somewhat  simplifies 
antiseptic  methods,  since  it  makes  the  use  of  a  macintosh 
unnecessary. 

Lister  states  that  the  new  compound  may  be  prepared 
ytry  cheaply.  It  is  only  necessary  to  send  to  a  slaugh- 
ter-house, have  the  blood  of  a  horse '  stirred  while  co- 
agulating, and  in  this  way  separate  the  clot.  "  You 
then,"  he  says,  "  have  several  gallons  of  serum/*  This 
is  mixed  with  the  sublimate  in  the  proportions  of  i  to  75, 
to  I  to  150. 

Not  many  cases  are  reported  showing  the  practical 
value  of  the  new  compound,  though  its  germicidal 
powers  are  accurately  demonstrated. 

Perhaps  Sir  Joseph  would  have  done  well  if  he  had 
studied  the  results  of  the  use  of  corrosive  sublimate  by 
other  surgeons  more  extensively. 

In  a  series  of  articles  recently  published  by  Professor 
J.  Mikulicz,  of  Krakau  (  Wiener  Medicin,  Wochenschr.^ 
Nos.  142,  143,  1884),  a  number  of  cases  are  reported  in 
which  toxic  symptoms  were  produced  by  the  use  of  irri- 
gating solutions  (i  to  1,000  or  i  to  2,000).  The  danger 
is  not  confined  to  the  patients,  but  extends  to  nurses 
and  surgeons ;  and  Mikulicz  adds  that  in  his  opinion 
sublimate  is  more  dangerous  than  carbolic  acid  or  iodo- 
form. 

We  look  forward,  therefore,  to  the  practical  outcome 
of  Sir  Joseph's  highly  important  and  scientific  contribu- 
tion with  much  interest,  but  with  some  incredulity. 


^ewTB  of  Viiz  ?82ftjejcti. 


The  Clinical  Society  of  the  New  York  Post- 
graduate Medical  School  is  the  title  of  a  society  re- 
cently organized  in  this  city.  It  is  composed  of  the  pro- 
fessors, other  teachers,  and  the  matriculants  of  the 
school. 

Bequest  to  a  Hospital, — By  the  will  of  the  late 
Mrs.  L.  J.  Kowles,  the  sum  of  $25,000  is  bequeathed 
to  the  City  Hospital,  Worcester,  Mass. 


Cholera  in  Paris. — Our  latest  medical  exchanges 
from  Paris  speak  somewhat  incredulously,  if  not  face* 
tiously,  of  the  possibility  of  an  epidemic  of  cholera  oc- 
curring this  year  in  that  city.  Despite  this,  the  epidemic 
is  already  upon  them,  and  is  advancing  rapidly.  It  was 
announced  in  the  Journal  Officiel  that  one  case  of  chol- 
era had  occurred  in  Paris  before  November  ist.  On 
November  7th,  it  was  stated  that  there  were  several  cases 
in  the  city,  and  that  one  death  had  occurred.  Five  days 
later  83  deaths  were  reported  and  119  cases  were  ad-- 
mitted  to  the  hospitals.  Another  despatch  says  that  on 
November  nth  there  were  152  fresh  cases  and  56  deaths,, 
and  that  the  total  number  of  cases  to  date  is  252. 

As  to  the  origin  of  the  epidemic  accounts  at  present 
differ.  One  report  states  that  the  disease  has  been  in 
the  city  since  June  last,  but  has  till  now  been  kept  re- 
stricted. This  is  extremely  improbable.  M.  Brouardel 
states  that  the  disease  originated  among  the  rag-pickers 
of  the  densely  populated  Faubourg  St.  Antoine,  who 
became  infected  by  imported  rags. 

It  is  improbable  that  Paris  will  receive  a  serious  visi- 
tation of  the  disease  so  late  in  the  season. 

Death  of  T>k,  Joseph  Allison  Reed. — Dr.  Joseph 
Allison  Reed,  the  Superintendent  of  the  Dixmont  In- 
sane Asylum,  died  suddenly  this  week,  of  kidney  disease, 
at  Pittsburg.  Dr.  Reed  was  born  at  Washington,  Penn.,, 
December  31,  1823.  He  studied  at  Jefferson  Medical 
College,  where  he  received  the  degree  of  Doctor  of 
Medicine  in  1847.  In  1857,  he  was  appointed  Superin- 
tendent of  the  Western  Pennsylvania  Hospital  for  the 
Insane.  Dr.  Reed  made  the  treatment  of  the  insane  hi& 
especial  study.  He  obtained  from  the  Legislature  the 
necessary  appropriation  for  a  new  hospital  building,  and 
under  his  supervision  the  edifice  at  Dixmont  was  erected.. 
Dr.  Reed  was  a  member  of  the  Allegheny  County  Medi- 
cal Society,  the  American  Association  of  Medical  Super- 
intendents of  Insane  Asylums,  and  the  American  Social 
Science  Association. 

No  Authority  for  Prohibiting  the  Importation  or 
Rags. — Epidemics  arouse  an  interest  in  very  curious, 
things.  A  while  ago,  the  American  hog  was  the  object 
of  international  solicitude  and  diplomatic  entanglements. 
Now  it  is  rags.  We  are  informed  by  the  Journal  of 
Commerce  that  the  Secretary  of  the  Treasury  has  no 
authority  to  prevent  the  importation  of  rags,  and  that  his. 
order  is  illegal ;  also  that  rags  never  carry  contagion  any 
way,  and  the  Secretary's  edict  is,  therefore,  as  unwise  as- 
it  is  illegal.  In  this  connection  we  may  observe  that  a. 
new  and  cheap  method  of  disinfecting  rags  in  bulk  has 
been  recently  devised  and  has  been  pronounced  a  de- 
cided success. 

Rupture  of  the  Penis. — Dr.  H.  A.  Veazie  reports 
in  the  New  Orleans  Medical  and  Surgical  Journal^  a 
case  of  true  fracture  of  the  penis.  The  patient  gave  his 
history  as  follows  :^^'  I  was  having  connection,  and  during 
the  excitement  the  party  with  whom  I  was  having  inter- 
course withdrew  suddenly,  and  as  I  followed  her  my 
penis  struck  a  bone,  and  I  felt  the  organ  break,  with  in- 
tense  pain.    I   examined  it,  saw  that  it  was  swelling 


550 


THE.  MEDICAL  RECORD. 


[November  15,  1884. 


rapidly  and  bleeding  from  the  canal.  I  felt  like  urinat- 
ing, and  tried  to  do  so,  but  could  not,  and,  as  I  tried,  the 
penis  pained  more  and  became  more  swollen."  He  then 
showed  me  his  penis  and  it  was  bleeding  from  the  meatus, 
the  organ  itself  very  much  swollen.  On  examination  I 
found  that  the  penis  had  been  broken  through  and  through, 
except  the  cutaneous  covering.  The  two  fragments  could 
be  moved  upon  each  other,  and  on  making  traction  a 
•distinct  sulcus  could  be  felt  at  the  scat  of  the  break, 
which  was  about  one  inch  and  a  half  back  of  the  corona. 
The  urethral  spongy  body  andt  he  corpora  cavernosa  were 
evidently  broken  through.  He  ultimately  recovered. 
Dr.  Veazie  states  that  this  is  the  first  case  of  the  kind  re- 
ported in  this  country. 

[The  late  Dr.  Valentine  Mott  reported  two  similar 
cases  in  1848  to  the  New  York  Academy  of  Medicine 
<"  Trans.  N.  Y.  Acad.  Med.,"  vol.  i.,  p.  99),  and  referred 
to  several  others. — Ed.'J 

The  Elevated  Railroad  and  Injuries  to  the 
Eye. — The  elevated  railroad  has  proved  quite  prolific 
in  injuries  to  the  eye  caused  by  the  fine  steel  filings 
thrown  into  the  air  by  the  use  of  the  brakes,  and  the 
sparks  from  the  locomotives  have  occasionally  also 
caused  injuries  of  the  same  sort.  A  case  of  the  latter 
kind  came  before  the  City  Court  a  short  time  since  and 
the  jury  awarded  a  verdict  of  $250  to  the  sufferer.  The 
judgment  was  appealed  from  and  the  General  Term  has 
just  affirmed  it.  Chief  Justice  McAdam,  in  delivering  the 
opinion,  said  that  the  elevated  railroads  were  bound  to 
use  the  most  approved  methods  of  preventing  the  escape 
of  sparks. 

A  Sanitary  Convention.— The  West  has  a  penchant 
for  sanitary  conventions.  One  of  these  highly  useful 
meetings  will  be  held  at  East  Saginaw,  Mich.,  on  De- 
cember 2d  and  3d,  under  the  auspices  of  the  State  Board 
•of  Health.  *  j 

Professor  von  Pettenkofer  on  the  Non-conta- 
ciousness  of  Cholera. — At  a  medical  meeting  in  Mu- 
nich, October  15th,  Professor  von  Pettenkofer  said:  "I 
think  that  we  all  have  good  reason  now  to  break  with  conta- 
gionist  views  of  the  spread  of  cholera — we  have  sacrificed 
milliards  owing  to  this  false  doctrine.  I  declare  openly 
that  I  now  must  uphold  my  localist  point  of  view  all  the 
more  firmly,  and  with  all  the  greater  conviction,  as  no 
proof  has  been  brought  against  it  even  by  Koch's  inves- 
tigations. An  experiment  ought  now  to  be  made  to  see 
if  cholera  can  really  be  produced  by  Koch's  comma- 
bacillus;  hitherto,  experiments  on  animals  have  been  un- 
successful. 1  will,  with  pleasure,  undertake  to  swallow 
bacilli  cultivated  by  Koch  himself,  [fl-ovided  that  there  is 
no  temporal  or  local  disposition  for  cholera  (that  is,  that 
cholera  is  not  prevailing),  as  is  the  case  now  in  Munich. 
Wars  have  been  fought  and  men's  lives  have  been  sacri- 
ficed for  objects  of  less  importance ;  the  enormous  ad- 
vantage is  here  so  obvious,  that  the  life  of  one  individual 
is  nothing  in  comparison  to  it.  My  example,  which,  I 
repeat,  I  would  carry  out  with  the  greatest  calmness, 
will  find  imitators.  Twenty  medical  men  would  easily 
be  found  to  follow,  hundreds  would  join  them  afterward, 
and  we  should  be  able  to  judge  from  the  result."  Petten- 
kofer even  declared  he  would  see  to  his  individual  disposi- 
tion for  it,  by  acquiring  catarrh  of  the  stomach  or  intestine. 


"I  value  Koch  as  a  bacteriologist  very  highly,  and  ac- 
knowledge his  services  in  the  fullest  degree,  but  the  con- 
clusions which  he  deduces  from  his  investigations  I  must 
directly  dispute." 

National  Conference  of  State  Boards  op 
Health. — At  a  preliminary  meeting,  held  in  the  city  of 
Washington,  D.  C,  in  May,  1884,  representatives  from 
eighteen  State  Boards  of  Health  being  present,  the  Na- 
tional Conference  of  State  Boards  of  Health  was  pro- 
visionally organized ;  and  it  was  decided  that  its  meet- 
ings should  be  held  at  the  same  times  and  places  with 
those  of  the  American  Public  Health  Association.  In 
pursuance  of  this  decision,  and  in  response  to  the  call  of 
the  Secretary,  Dr.  J.  N.  McCormack,  of  Kentucky,  the 
first  annual  meeting  of  the  Conference  was  held  in  St. 
Louis,  beginning  on  Monday,  October  13,  1884,  the 
Hon.  Erastus  Brooks,  of  New  York,  in  the  chair,  and 
representatives  from  twenty  States  and  from  Canada  be- 
ing present.  Papers  upon  cholera  were  read  by  Dr. 
John  H.  Rauch,  by  Dr.  Charles  Smart,  and  by  Dr.  C. 
W.  Chancellor,  of  Baltimore.  An  address  embodying 
the  views  of  the  conference  as  to  the  prevention  of  chol- 
era was  adopted,  and  was  subsequently  indorsed  by  the 
American  Public  Health  Association.  The  Conference 
adjourned  to  meet  in  Washington,  December  loth. 

A  Medical  Practice  Act  Declared  Constitu- 
tionat., — On  November  ist,  says  the  New  York  Medical 
Journal^  the  Court  of  Appeals  of  West  Virginia  decided 
that  the  medical  practice  act  of  that  State  was  constitu- 
tional. This  is  a  substantial  and  practical  indorsement 
of  the  good  work  done  by  the  State's  Board  of  Health. 

Doctors  who  Died  of  Cholera. — Of  one  hundred 
and  thirty-nine  physicians  engaged  in  attending  cholera 
patients  in  Naples  under  the  White  Cross  Society, 
twenty  died. 

The  Late  Dr.  Rabbeth. — Sir  William  Gull  suggests 
that  a  gold  medal  be  struck  in  commemoration  of  the 
self-sacrifice  of  Dr.  Rabbeth,  who  died  of  diphtheria  con- 
tracted by  sucking  out  the  tracheotomy-tube  of  a  diph* 
theritic  patient. 

Death  from  Methylene. — A  young  man,  nineteen 
years  of  age,  was  given  methylene  by  Mr.  William  Square, 
Surgeon  to  the  East  Cornwall  Hospital,  Plymouth,  Eng- 
land, in  order  to  have  an  operation  performed  After 
getting  well  under  the  anaesthetic,  the  patient  suddenly 
died  of  paralysis  of  the  heart.  The  heart  was  byper- 
trophied,  but  otherwise  normal.  The  proportion  of 
deaths  from  methylene  is  about  one  in  eight  thousand. 

American  Priority  in  the  Discovery  of  Cocaine 
(Erythroxyline). — We  are  glad  to  give  prominence  to 
the  following  letter  from  Dr.  Samuel  R.  Percy,  of  this  city, 
in  which  he  puts  in  a  claim,  apparently  a  just  one,  of 
priority  in  the  discovery  of  cocaine,  or  as  he  called  it, 
"erythroxyline."  He  writes  :  "On  November  4,  1857, 
I  read  before  the  New  York  Academy  of  Medicine  an 
exhaustive  paper  upon  the  leaf  of  the  plant  erythroxylon 
coca^  and  stated  that  I  was  busy  in  its  chemical  investiga- 
tion. On  December  2, 1857, 1  exhibited  to  the  Academy 
of  Medicine  one  scruple  of  the  alkaloid  of  the^  leaves  to 
which  I  gave  the  name  erythroxyline.  At  the  same  time 
I  left  with  the  librarian  of  the  Academy  this  scruple  of 
erythroxyline,  a  quantity  of  fluid  extract  and  some  solid 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


551 


extract,  and  also  a  fine  sample  of  the  leaves.  I  read 
before  the  Academy  the  method  of  preparing  the  alkaloid 
and  a  number  of  physiological  experiments  upon  dogs. 
1  then  stated  that  the  hydrochlorate  of  erythroxyline  had 
a  peculiar  but  not  unpleasant  benumbing  and  paralyzing 
effect  upon  the  tongue,  unlike  that  produced  by  aconitia 
and  not  so  persistent.  The  librarian  of  the  Academy  has 
been  unable  to  find  the  paper  or  the  alkaloid,  but  the  fact 
of  such  a  paper  having  been  read,  and  such  an  exhibit 
having  been  shown,  is  recorded  on  the  books  of  the 
Academy.  I  still  hope  to  find  the  paper.  Some  three 
years  after  this,  Niemann,  in  Germany,  discovered  the 
same  alkaloid,  and  in  his  announcement  called  it  'co- 
caine.' Immediately  upon  this  announcement  I  reiter- 
ated the  priority  of  my  discovery  in  Dr.  Stephen  Smith's 
Medical  Times.  1  also  personally  saw  Mr.  George  Wood, 
of  Philadelphia,  and  he  promised  that  in  the  next  edition 
of  the  United  States  Dispensatory  the  subject  should  be 
fairly  stated.  He  forgot  it.  The  name  cocaine  is  not  a 
correct  one,  it  is  almost  universally  called  cocaine,  lead- 
ing one  to  suppose  that  it  is  a  product  from  the  cocoa 
berry.  With  its  correct  name  erythroxyline  it  cannot  be 
mistaken.  As  an  American,  I  claim  the  name  given  to 
it  in  America,  and  hope  that  every  American  surgeon, 
will  do  the  same.** 

The  Opening  of  the  Bridgeport  Hospital. — The 
opening  ceremonies  of  this  hospital  took  place  on  Tues- 
day, November  nth.  A  number  of  prominent  physicians 
and  surgeons  from  this  city  were  present.  An  eloquent 
and  appropriate  address  was  delivered  by  Dr.  D.  R  St. 
John  Roosa.  The  meeting  of  the  Fairfield  County  Med- 
ical Society  preceded  the  exercises  at  the  inauguration 
ojf  the  hospital.  Dr.  Wilson,  of  Bridgeport,  demonstrated 
the  efficiency  of  the  new  local  anaesthetic,  hydrochlorate 
of  cocaine,  by  experiments  upon  the  conjunctiva,  and  by 
hypodermic  injections  prior  to  the  removal  of  a  timior  of 
the  forehead.  The  tumor  was  removed  by  Dr.  Weir 
without  pain.  Dr.  Weir  made  an  address  upon  '^  Hos- 
pitals and  Hospital  Surgeons  in  Germany."  Dr.  Wile, 
Dr.  Mund6,  and  Dr.  Cromack  also  addressed  the  Society. 

Female  Internes  in  Paris  Hospftals. — A  cable 
report  states  that  the  medical  and  surgical  societies  con- 
nected with  the  Paris  hospitals  have  voted  on  no  occa* 
sion  to  admit  women  to  compete  for  hospital  positions. 

How  Cholera  Originates. — The  account  given  in 
The  Lancet  of  the  outbreak  of  cholera  at  Yport,  Nor- 
mandy, is  most  instructive  :  "  On  September  25th  some  of 
the  crew  of  a  French  fishing-boat  that  had  come  from 
Newfoundland,  and  was  anchored  at  Cette,  one  of  the 
cholera-stricken  towns  in  the  south  of  France,  arrived  at 
Fecamp,  a  small  seaport  town  in  Normandy,  not  far  from 
those  above  named.  These  men  travelled  by  rail  from 
Cette,  and  on  their  arrival  at  Fecamp,  which  is  near  to 
their  home,  they  had  to  take  a  sulphur  bath,  and  fresh 
clothes  were  issued  to  them  before  they  were  allowed  to 
go  any  farther.  Unfortunately,  however,  their  own 
clothes,  which  were  supposed  to  have  been  thoroughly 
disinfected  (having  gone  through  the  form),  were  given 
back  to  them.  On  Octol^r  4th  some  of  the  disinfected 
clothes  were  washed  in  the  sea  by  a  female  peasant,  who 
fell  suddenly  ill,  and  died  in  a  few  hours ;  the  physician 
who  attended  her  at  once  recognized  the  malady  as  being 


Asiatic  cholera.  The  victim  was  sister-in-law  to  one  of 
the  sailors,  who  was  not  affected  by  the  disease,  nor,  in- 
deed, were  any  of  the  others  who  accompanied  him  from 
Cette.  The  disease  spread  rapidly,  and  in  the  next  day 
or  two  ten  persons  were  attacked,  of  whom  seven  died, 
and  the  other  three  recovered." 

Notes  and  Correspondence  on  the  Use  of  Muri- 
ate OF  Cocaine. — At  a  meeting  of  the  Royal  Society  of 
Physicians  of  Vienna,  Dr.  KoUer  announced  his  discov- 
ery of  the  use  of  cocaine  in  producing  anaesthesia  of  the 
conjunctiva.  It  seems  that  he  began  his  experiments 
upon  animals  in  the  laboratory  of  Professor  Strieker.  He 
then  tried  it  upon  the  human  eye  with  results  already 
known.     He  used  a  two  per  cent,  solution. 

Docent  Dr.  Konigstein  announced  that  independently 
at  the  same  time  he  had  made  the  same  discovery.  He 
had  used  a  one  per  cent,  solution.  Dr.  Konigstein  states 
that  it  produces  enlargement  of  the  palpebral  fissure,  and 
protrusion  of  the  eyeball  and  dilatation  of  the  pupil.  He 
thinks,  therefore,  that  it  acts  upon  the  sympathetic. 

In  London,  at  a  meeting  of  the  Ophthalmological  So- 
ciety, October  9th,  Dr.  Arthur  Benson,  of  Dublin,  Mr. 
Marcus  Gunn,  and  Mr.  Nettleship  described  the  effects  of 
cocaine  upon  the  eye. 

Dr.  J.  R.  Uhler,  of  Baltimore,  writes  to  the  Maryland 
Medical  Journal  that  he  has  found  that  a  solution  of  mu- 
riate of  cocaine  applied  to  the  vulva  mitigates  the  pains 
of  labor. 

Dr.  E.  S.  Peck  writes  in  correction  'of  a  note  pub- 
lished last  week  regarding  the  price  of  cocaine.  It  now 
costs  only  thirty-five  cents  a  grain^  or  less. 

Dr.  W.  Oliver  Moore  writes  that  in  eye  surgery  co- 
caine is  six  times  cheaper  than  ether,  as  3  ij.  of  a  two 
per  cent,  solution  lasts  for  twelve  operations,  and  costs 
$1.50 ;  ether  for  the  same  would  cost  from  $9  to  $12. 

Dr.  H.  G.  Sherman,  of  Cleveland,  O.,  has  success- 
fully used  cocaine  as  a  local  application  for  tinnitus  au- 
rium.  A  patient  suffering  from  chronic  otitis  media,  who 
had  long  been  treated  by  all  known  methods,  came  to 
him  suffering  intensely  with  noises  in  the  ears.  A  four 
per  cent,  solution  of  cocaine  was  instilled  into  the  ear. 
Tinnitus  and  deafness  were  lessened.  A  second  case 
was  tried  with  similar  result?. 


Whooping-Cough  and  Resorcin. — A  monograph  on 
the  nature  and  treatment  of  whooping-cough  has  re- 
cently appeared  at  Rio  de  Janeiro  from  the  pen  of  Dr. 
Moncorvo.  He  accepts  in  a  great  measure  the  con- 
sequences of  the  germ  theory  as  regards  pertussis  and 
looks  on  the  affection  as  due  to  the  presence  of  micro- 
cocci, which  proliferate  abundantly  upon  the  mucous 
membrane  which  coats  the  upper  part  of  the  larynx 
above  the  rima  glottidis,  where  the  epithelial  cells  become 
infiltrated,  and  which  region  appears  to  be  the  seat  of 
election  for  the  proliferation  of  the  micrococci.  Resorcin 
directly  applied  to  the  mucous  membrane  of  the  region 
indicated  has  led  to  diminution  in  the  number  of  spas- 
modic attacks,  which  lose  their  intensity,  while  the  total 
duration  of  the  disease  is  shortened.  The  benefit  is  said 
to  be  wholly  due  to  the  resorcin,  because  no  other  means 
were  employed.  The  drug  was  used  in  the  strength  of  a 
one  per  cent,  aqueous  solution  as  a  topical  application, 
by  means  of  a  soft  brush  mounted  on  a  long  handle. 
The  application  was  made  three,  four,  or  five  times  a 
day. — London  Lancet^  October  18,  1884. 


552 


THE  'MEDICAL  RECORD, 


[November  15,  1884. 


^epavte  at  S^acUtits. 


NEW  YORK   PATHOLOGICAL   SOCIETY. 

Stated  Meetings  October  22,  1884. 

George  F.  Shrady,  M.D.,  President,  in  the  Chair. 

GENERAL   CARCINOSIS. 

Dr.  John  A.  Wyeth  presented  a  specimen,  accompanied 
by  the  following  history,  furnished  by  his  house-surgeon 

at  the  Mount  Sinai  Hospital :  Franz  S ,  aged  thirty 

years,  a  native  of  Germany,  single,  and  a  machinist,  was 
admitted  September  loth.  Last  May  the  patient  noticed 
a  swelling  at  the  left  side  of  the  umbilicus.  It  gave  him 
no  pain.  It  gradually  increased  in  size  downward  and 
forward  until  it  gave  him  great  inconvenience  from 
its  size,  weight,  and  position.  During  the  last  four 
months  the  patient  has  lost  eighty  pounds  in  weight,  has 
had  for  some  time  a  cough,  with  some  expectoration, 
occasionally  bloody.  Last  April  the  patient  had  his  left 
testicle  removed  at  the  German  Hospital,  presumably 
for  tubercular  disease.  Of  late  the  pain  in  the  abdomical 
tumor  has  become  so  severe  that  it  prevents  him  from 
sleeping.  There  was  no  history  of  gonorrhoea,  chancre, 
or  rheumatism ;  no  oedema.  One  brother  and  his  moth- 
er died  of  phthisis,  a  remaining  sister  has  some  lung 
trouble. 

On  admission  the  patient  has  a  large  tumor  involving 
the  umbilical,  left  inguinal,  and  left  lumbar  regions, 
extending  about  two  inches  to  the  right  of  the  umbilicus 
downward  almost  to  the  symphysis  pubis,  and  also 
around  to  the  back.  The  tumor  is  painful  on  pressure. 
Pressure  over  the  region  of  the  left  kidney  gives  rise  to 
pain  also  on  the  under  surface  of  the  liver  and  over  the 
left  upper  half  of  the  thorax,  especially  near  the  sternum. 
There  is  some  bulging  at  the  upper  part  of  the  left  side 
of  the  chest  anteriorly,  and  the  outline  of.  the  clavicle  is 
entirely  obliterated.  The  left  axillary  and  supra- clavicular 
glands  are  much  enlarged.  The  abdominal  tumor  has 
a  nodular  feel,  and  a  number  of  small,  nodular  bodies 
can  be  felt  near  it. 

Physical  examination  of  the  lunss  revealed  slight  dul- 
ness  and  broncho-vesicular  breathmg  at  the  right  apex 
anteriorly;  marked  dulness,  diminished  voice  and  breath- 
ing ;  crepitant,  subcrepitant,  and  sonorous  rales  at  the 
left  apex  anteriorly.  There  was  resonance  between  the 
splenic  dulness  and  the  tumor. 

The  patient  had  marked  laryngitis,  loss  of  voice,  and 
spasmodic  cough.  There  had  been  no  haematuria  at  any 
time.  He  was  much  emaciated,  his  appetite  was  poor, 
temperature  100**  F.,  and  he  complained  of  constant 
pain. 

September  i6th. — Great  pain  in  the  left  leg  and  thigh, 
limb  cold  and  mottled,  and  foot  anesthetic.  No  pulsa- 
tion in  the  femoral  artery.  The  swelling  of  the  left  lower 
extremity  continued  to  increase,  accompanied  with  pain 
along  the  course  of  the  artery,  and  on  September  2  2d 
several  large  blebs  were  observed  near  the  ankle.  The 
general  condition  of  the  patient  grew  worse,  and  he  died 
on  October  15th,  with  symptoms  of  pulmonary  oedema. 

Autopsy, — On  opening  the  abdomen  a  large  tumor  was 
found  occupying  the  left  inguinal  and  lumbar  regions, 
and  covered  by  the  adherent  mesentery.  The  abdominal 
wall  was  not  involved.  The  tumor  was  firmly  attached 
to  the  vertebral  column,  and  to  it  were  attached  the 
descending  colon  and  left  kidney.  The  ureter  had  been 
compressed  by  the  tumor  and  hydro-nephrosis  had  re- 
sulted. The  tumor  seemed  to  arise  from  glands  in  the 
lower  dorsal  and  lumbar  regions,  and  had  surrounded  the 
aorta  and  vena  cava  completely.  The  vertebral  column 
and  intervertebral  cartilages  appeared  healthy.  The 
left  external  iliac  artery  was  flattened  and  nearly  occluded 
by  the  tumor,  and  there  was  thrombosis  of  the  iliac  vein 
extending  down  into  the  left  femoral.  The  mesenteric 
glands  were  involved,  as  also  were  the  glands  passing 


below  Poupart's  ligament,  with  the  femoral  vessels.  The 
anterior  mediastinum  was  occupied  by  a  new  growth, 
which  was  attached  to  the  sternum,  and  extended  back- 
ward about  one  inch  behind  the  trachea,  surrounding  it 
and  the  great  vessels  of  the  neck.  The  apex  of  the  left 
lung  was  pushed  to  the  left  by  the  tumor,  and  the  upper 
lobe  was  infiltrated  with  the  new  growth.  The  upper 
lobe  of  the  left  lung  also  contained  numerous  cavities, 
and  there  was  marked  bronchitis  and  laryngitis.  The 
right  lung  appeared  normal.  The  liver  showed  numer- 
ous broken-down  white  foci,  varying  in  size  from  one- 
fourth  to  two  inches  in  diameter.  The  kidneys  were 
congested,  the  spleen  and  stomach  were  normal,  and  the 
bladder  contained  nodules  similar  to  those  seen  in  the 
liver.     The  brain  was  not  examined. 

The  specimen  had  been  examined  by  the  pathologist 
of  the  hospital,  who  pronounced  the  new  growth  to  be  can- 
cerous, probably  originating  in  the  lumbar  glands,  with 
metastasis  into  the  mediastinum  and  other  organs  of  the 
body.  The  point  of  interest  in  the  case  was  thie  fact 
that  the  patient  was  operated  upon  for  removal  of  a 
tumor  of  the  testicle,  which  was  considered  to  be  tuber- 
cular in  character,  and  within  a  few  months  subsequently 
a  new  growth  occurred  in  the  line  of  the  lymphatics  upon 
the  same  side  of  the  body,  which  growth  was  carcinoma- 
tous, and  was  followed  by  malignant  growths  in  the  lungs, 
liver,  bladder,  and  mediastinum.  The  testicle  was  re 
moved  by  his  colleague,  Dr.  Gerster,  who  had  presented 
it  to  the  Society  as  a  tubercular  testis,  and  on  examining 
the  records  of  the  German  Hospital  it  was  found  that  the 
case  was  recorded  there  as  one  of  tubercular  disease  of 
the  testicle. 

The  Secretary  thought  that  the  group  of  testicles 
which  Dr.  Gerster  presented  to  the  Society  had  not  been 
examined  microscopically  when  exhibited,  and  therefore 
it  might  be  possible  that  the  specimen  referred  to  by  Dr. 
Wyeth  was  cancerous.  [The  records  show  that  the  tes- 
ticles presented  by  Dr.  Gerster  had  not  been  examined 
microscopically.  They  were  referred  to  the  Committee 
on  Microscopy.     W.  M.  Carpenter,  Secretary.]J 

inhalation  of  a  blow-gun  dart — tracheotomy- 
exploration  OF  THE  TRACHEA  AND  PRIMARY  BRON- 
CHI—FAILURE TO  REMOVE  THE  FOREIGN  BODY  WITH 
INSTRUMENTS — SPONTANEOUS  REMOVAL  SUBSEQUENTLY 
— RECOVERY  OF  THE   PATIENT. 

Dr.  Wyeth  presented  a  specimen  which  related  to 
tracheotomy  performed  in  an  attempt  at  removal  of  a 

foreign  body  from  the  trachea  or  bronchi.     A.  A ,  of 

Wallingford,  Conn.,  ten  years  of  age,  on  September  7th, 
while  in  the  act  of  blowing  a  dart  gave  a  forced  inspira- 
tion and  sucked  the  dart  into  his  trachea.  Violent 
coughing  immediately  followed.  Respiration  became 
difficult.  The  boy  turned  blue  in  his  face,  and  his  mother 
thought  he  was  choking  to  death.  The  immediate  symp- 
toms of  suffocation,  however,  soon  disappeared.  Between 
that  date  and  September  loth  the  boy  was  carefully  exam- 
ined by  the  family  physician  who  concluded  that  the 
foreign  body  had  been  carried  down  through  the  trachea 
and  had  lodged  in  the  right  bronchus. 

On  September  nth  the  patient  was  brought  to  New 
York,  when  Dr.  Wyeth  examined  him  and  reached  the 
conclusion  that  there  was  a  foreign  body  in  the  right 
bronchus.  He  also  called  Dr.  Learning  and  Dr.  Elsberg 
in  consultation,  and  Dr.  Elsberg  gave  the  opinion  that 
the  foreign  body  was  located  in  the  right  bronchus,  al- 
though he  was  unable  to  see  it.  Dr.  Learning  examined 
the  patient,  and  located  the  foreign  body  in  the  second 
bifurcation  of  the  right  bronchus  anteriorly,  basing  his 
diagnosis  not  only  upon  the  hissing  rA.le  heard  immedi- 
ately over  that  portion  of  the  bronchial  tube,  but  upon 
the  fact  that  there  was  associated  with  it  an  area  in 
which  the  normal  vesicular  respiration  was  entirely  ab 
sent. 

On  the  following  day  chloroform  was  administered, 
and  l^x,  Wyeth  performed  tracheotomy  just  above  the 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


553 


sternum,  introduced  his  little  tinger,  passed  it  toward 
the  bifurcation,  but  was  unable  to  touch  it  He  then 
turned  his  finger  upward,  explored  the  trachea  and  lar- 
ynx, but  was  unable  to  find  any  foreign  body.  He  then 
introduced  a  pair  of  angular  forceps  into  the  trachea, 
passed  them  downward  to  the  bifurcation,  turned  the  in- 
strument into  the  right  bronchus,  and  began  to  fish  for 
the  body  in  the  following  manner :  He  opened  the  in- 
strument to  the  extent  of  one-fourth  of  an  inch,  pro- 
jected it  one-fourth  of  an  inch,  and  then  withdrew  it, 
and  went  on  in  this  manner  exploring  all  four  quarters 
of  the  bronchial  circumference.  He  did  this  throughout 
the  entire  right  bronchus,  but  did  not  touch  anything 
which  felt  like  a  foreign  body. 

He  then  took  a  piece  of  ordinary  surgeon's  wire,  at 
the  suggestion  of  Dr.  Learning,  made  a  loop,  carried  it 
in  without  difficulty,  and  fished  again  in  the  region  which 
he  had  explored  with  the  other  instrument,  but  was  un- 
able to  find  any  foreign  body.  He  then  concluded  that 
the  foreign  body  was  lodged  beyond  surgical  reach,  and 
further  operative  interference  was  discontinued.  The 
patient  rallied  firom  the  chloroform, .  and  subsequently 
did  well,  only  a  moderate  elevation  of  temperature  ensu- 
ing, which  soon  subsided. 

Dr.  Wyeth  kept  the  operation  wound  opened  by 
stitching  two  rings  of  the  trachea  with  fine  silk  suture  to 
the  integument  on  each  side,  and  fastening  the  ends  of 
the  suture  behind  with  adhesive  plaster,  which  left  the 
opening  patent  to  the  fullest  extent.  He  left  the  wound 
open  because  he  thought  that  perhaps  the  foreign  body 
when  loosened,  if  it  was  loosened,  might  lodge  in  the 
larynx,  and  the  patient  would  suffocate  before  it  could  be 
removed,  whereas,  if  the  wound  was  open,  it  would 
probably  lodge  there  as  it  came  up  from  the  bronchus. 

On  September  24th,  twelve  days  after  the  operation, 
he  called  Dr.  J.  H.  Ripley,  Dr.  A.  Jacobi,  and  Dr. 
E.  G.  Janeway  in  consultation.  Dr.  Jacobi  was  doubtful 
as  to  the  presence  of  any  foreign  body  in  the  lungs.  Dr. 
Janeway  said  that,  from  the  physical  signs,  he  did  not 
feel  like  saying  there  was  a  foreign  body  in  the  lungs,  yet 
he  thought  it  was  safe  to  treat  the  patient  as  if  there  was 
one  there.  Dr.  Ripley  believed  there  was  a  foreign  body 
m  the  lungs,  but  was  of  the  opinion  that  it  had  been 
shifted  from  the  right  to  the  left  bronchus,  because  while 
there  was  the  same  sound,  but  less  intense,  heard  at  the 
point  where  the  original  rile  was  discovered,  there  was 
at  the  same  time  diminished  respiratory  murmur  all  over 
the  If//  lung,  which  was  recognized  by  all  the  consulting 
physicians  at  the  time  the  examination  was  made.  Dr. 
Ripley  thought  that  the  patient  had  coughed  the  dart  up, 
and  that  with  the  next  inspiration  it  was  returned  and 
lodged  in  the  primary  bronchus  on  the  left  side. 

The  result  of  the  consultation  was  that  the  tracheal 
wound  should  be  kept  open  by  means  of  a  canulated 
silver  tracheal  tube,  and  on  the  next  morning  Dr.  Wyeth 
administered  chloroform  and  opened  up  the  wound  in  the 
trachea,  which  had  in  good  part  united.  He  also  deter- 
mined, after  the  wound  was  opened,  to  explore  the  left 
bronchus,  and  to  facilitate  this  procedure  he  laid  the  boy 
upon  the  operating-table  on  his  right  side,  with  the  head 
hanging  well  over  the  edge  of  the  table,  so  that  any  blood 
which  might  be  caused  by  the  finger  coming  in  contact 
with  the  granulation  tissue  would  run  out  of  the  wound. 
As  he  pushed  his  little  finger  down  into  the  trachea  he 
prolonged  the  operation  for  perhaps  half  a  minute.  The 
boy's  face  turned  blue,  when  he  removed  the  finger  and 
the  patient  inspired  very  deeply,  and  immediately  after- 
ward coughed  and  made  a  violent  expiratory  effort 
While  tHe  patient  was  making  the  expiratory  effort  Dr. 
Wyeth  closed  the  tracheal  wound  completely  with  his 
thumb,  and  when  it  had  passed  off  he  immediately  intro- 
duced his  finger  a  second  time,  and  produced  the  same 
asphjTxia  with  the  same  result,  and  kept  his  finger  upon 
the  tracheal  wound  the  second  time.  During  this  entire 
procedure  no  foreign  body  was  discovered.  Dr.  Wyeth 
then  introduced  the  tracheal  tube,  was  about  ready  to  tie 


the  little  bands  behind  the  n^eck,  when  the  patient  began 
to  have  some  spasmodic  action  of  the  muscles  of  the 
larynx  and  the  respiratory  muscles  became  fixed  Sus- 
pecting that  the  tracheal  tube  had  become  obstructed  he 
immediately  removed  it,  found  it  clear,  and  just  at  that, 
moment  the  dart  was  seen  hanging  from  the  right  side  of 
the  mouth.  He  closed  the  tracheal  wound  immediately 
with  adhesive  plaster,  and  the  boy  made  an  uninterrupted 
recovery. 

In  reply  to  a  question,  Dr.  Wyeth  expressed  the  opin- 
ion that  the  foreign  bo^y  never  changed  its  location  un- 
til it  was  finally  removed  by  the  violent  expiratory  ef- 
fort. 

The  President  suggested  that  the  usual  rule  was  that 
when  such  bodies  became  impacted  in  the  trachea  or 
bronchial  tubes  they  were  expelled  by  the  first  violent 
expiratory  effort. 

Dr.  Wyeth  remarked  that  it  is  well  known  that  the 
trachea  and  bronchial  tubes  were  tolerant  of  foreign 
bodies,  and  referred  to  a  case  in  which  the  foreign  body 
remained  in  the  trachea  three  months  without  producing 
marked  symptoms,  and  was  then  expectorated. 

Dr.  H.  C.  Coe  referred  to  a  case  in  which  a  young 
man  inhaled  an  entire  head  of  timothy  grass.  As  a  re- 
sult of  this  it  was  supposed  that  he  had  some  chronic 
lung  trouble,  and  phthisis  had  been  diagnosticated. 
Nearly  a  year  afterward  he  coughed  up  the  foreign  body, 
immediately  began  to  regain  his  flesh  and  strength,  and 
ultimately  made  a  complete  recovery. 

Dr.  J.  Lewis  Smith  said  that  several  years  ago  he 
had  a  case  in  which  a  piece  of  a  shell  of  a  hickory- 
nut  was  drawn  into  the  lungs.  There  was  decided  dul- 
ness  on  percussion  over  a  circumscribed  area,  and  symp- 
toms of  fibroid  pneumonia  developed,  but  the  child 
subsequently  expectorated  the  foreign  substance  and  re- 
covered completely. 

The  President  thought  that  in  Dr.  Wyeth' s  case, 
where  the  point  of  the  pin  evidently  pointed  upward,  it 
was  safer  to  perform  tracheotomy,  explore  the  trachea 
and  bronchi,  rather  than  to  wait  for  spontaneous  removal 
of  the  foreign  body.  He  also  referred  to  a  case  in  which 
a  boy,  five  or  six  years  of  age,  inhaled  the  spiral  spring  of 
an  ordinary  spring  clothes-pin.  The  accident  occurred 
while  he  was  close  at  hand,  and  at  first  he  thought  the 
patient  would  die  of  suffocation,  but  he  succeeded  in 
catching  the  spiral  spring  with  the  end  of  his  finger  and 
removed  it.     It  had  lodged  in  the  top  of  the  larynx. 

Dr.  Furman  referred  to  a  case  in  which  a  patient, 
while  under  the  influence  of  chloroform  for  the  purpose 
of  having  a  tooth  extracted,  inhaled  a  fragment  of  one 
of  the  teeth,  and  it  entered  the  right  bronchus.  The  pa- 
tient suffered  two  or  three  weeks  from  bronchitis,  but 
finally  the  foreign  body  was  expelled. 

The  President  remarked  that  while  it  might  be  safe 
to  allow  rounded  bodies  to  remain  in  the  trachea  or 
bronchi,  and  await  spontaneous  removal,  it  would  be,  on 
the  contrary,  justifiable  to  perform  tracheotomy  where  ir- 
regular-shaped bodies  had  entered  the  respiratory  pas- 
sage and  become  fastened. 

Dr.  Wyeth  thought,  in  view  of  the  number  of  cases 
mentioned  in  which  the  foreign  body  had  been  removed 
from  the  lower  air-passages  spontaneously,  that  it  might 
be  a  question  whether  operative  interference  should  be 
resorted  to,  at  least  very  early. 

Dr.  W.  M.  Carpenter,  as  bearing  upon  this  point,  re- 
ferred to  a  paper  read  by  Dr.  Leaming  before  the  Sur- 
gical Section  of  the  New  York  Academy  of  Medicine,  in 
1879.  [O"  referring  to  Medical  Record,  vol.  xv.,  p. 
208,  it  will  be  seen  that  Dr.  Leaming  reported  six  cases 
of  foreign  bodies  in  the  air-passages.  In  three  cases  the 
foreign  body  was  expelled  spontaneously  ;  in  two  cases 
it  was  removed  by  operation.  In  one  of  the  sponta- 
neous cases  the  foreign  body  was  a  head  of  timothy,  and 
although  it  was  coughed  up,  the  patient  died  of  destruc- 
tion of  the  lung,  due  to  the  presence  of  the  head  of  hay. 
In  one  case  the  foreign  body,  a  portion  of  a  tooth,  re- 


554 


THE   MEDICAL  RECORD. 


[November  15,  1884. 


mained,  and  produced  disease  which  caused  the  patient's 
death. 

In  the  discussion  which  ensued  there  was  a  difference 
of  opinion  with  reference  to  the  early  performance  of 
tracheotomy.     W.  M.  C] 

Dr.  Carpenter  also  thought  that,  in  very  many  cases 
at  least,  the  symptoms  of  immediate  suffocation  pro- 
duced by  a  foreign  body  entering  the  lower  air-passages 
soon  subsided,  and  therefore  that  the  apparent  urgency 
for  immediate  operative  interference  passed  away. 

A  method  of  removing  foreign  bodies  from  the  larynx, 
such  as  coins,  etc.,  not  infrequently  practised  in  rural 
regions,  was  to  lift  the  child  suddenly  by  the  cars,  per- 
haps patting  him  on  the  back,  and  holding  the  head 
.  downward  at  the  same  time. 

TUMOR   OF  THE   BREAST. 

Dr.  W.  p.  Northrup  presented  a  microscopical  sec- 
tion of  a  tumor  of  the  breast,  which  was  removed  by  Dr. 
C.  C.  Lee  at  the  New  York  Foundling  Asylum.  The  pa- 
tient was  forty-five  years  of  age,  the  mother  of  ten  chil- 
dren. Just  before  the  birth  of  her  last  child  she  no- 
ticed a  lump  in  the  breast,  and  when  the  child  was  seven 
weeks  old  the  operation  was  performed  for  its  removal. 
The  tumor  was  situated  to  the  left  of  the  nipple,  and 
had  been  painless  for  the  most  part,  but  recently  it  had 
been  the  seat  of  occasional  lancinating  pains.  There 
were  two  or  three  enlarged  axillary  glands.  The  nipple 
was  markedly  retracted.  The  patient  had  been  seen  by 
five  or  six  surgeons  of  this  city,  who  made  a  diagnosis  of 
malignant  growth,  and  recommended  that  it  be  removed. 
The  tumor  was  about  the  size  of  an  ordinary  orange, 
very  firm  to  the  feel,  and  somewhat  lobulated.  There 
was  no  ulceration.  An  incision  was  made  at  the  outer 
side  of  the  tumor,  and  when  the  firm  mass  was  reached 
there  gushed  out  a  large  quantity  of  fetid  material  which 
looked  like  pus,  and  Dr.  Lee  supposed  that  he  had 
opened  an  abscess,  and  those  who  were  present  also 
supposed  that  the  cavity  opened  was  that  of  an  abscess. 
He  accordingly  pared  off  the  edges  to  remove  the  indu- 
ration as  far  as  possible.  In  this  he  had  no  difficulty 
with  reference  to  the  anterior  wall,  but  the  posterior 
wall  was  almost  of  a  cartilaginous  induration.  He  did 
not  remove  the  indurated  glands  of  the  axilla.  The 
wound  healed  almost  entirely  by  first  intention,  but  its 
edges  were  much  indurated  and  reddened ;  yet  when  the 
patient  left  the  hospital  the  induration  had  somewhat  di- 
minbhed,  and  the  enlargement  of  the  axillary  glands  was 
very  markedly  decreased.  The  prognosis  was  regarded 
as  very  doubtful,  as  probably  the  disease  would  return. 

The  tumor  microscopically  exhibited  a  multitude  of 
giant  cells,  such  as  seen  in  ordinary  inflammatory  tissue. 
The  specimen  had  been  examined  by  Dr.  Delafield, 
whose  ultimate  report  wsls,  that  one  or  two  weeks  before 
the  birth  of  the  child,  and  nine  weeks  before  the  opera- 
tion, there  was  probably  an  adenoma ;  that  subsequently 
an  abscess  developed,  and  that  the  adenomatous  tissue 
was  perforated  throughout  by  this  granulation  tissue, 
which  had  obscured  the  original  type  of  disease. 

It  was  also  possible  that  the  affection  was  only  an  ab- 
scess, with  induration.  The  probabilities,  however,  were 
that  the  original  tumor  was  an  adenoma,  that  an  abscess 
occurred,  and  that  the  giant  cells  were  simply  a  part  of 
the  granulation  tissue,  and  not  of  special  importance. 

The  President,  as  bearing  upon  this  case,  referred  to 
one  in  which,  two  years  ago,  he  removed  a  tumor  that, 
according  to  the  description,  presented  almost  exactly 
the  same  physical  appearance.  The  patient  was  forty 
years  of  age.  There  was,  however,  no  retraction  of  the 
nipple,  nor  was  the  skin  involved.  There  was  slight  en- 
largement of  one  of  the  glands  of  the  axilla.  The  cyst 
which  the  tumor  contained  was  so  tense  that  when  the 
knife  entered  it  the  fluid  contents  spurted  out  to  a  great 
distance  and  were  exceedingly  offensive.  He  removed 
the  remainder  of  the  growth,  and  also  parts  of  the  en- 
arged  glands  of  the  axilla.     At  that  time  he  regarded  the 


prognosis  as  very  good,  but  six  months  subsequently  en- 
larged glands  reappeared  in  the  axilla,  rapidly  put  on  a 
malignant  appearance,  and  were  removed.  Six  months 
afterward,  in  the  line  of  the  lymphatics,  the  supra-axillary 
glands  became  involved,  and  he  removed  a  very  large 
one  in  the  subclavian  triangle.  Both  of  these  tumors,  on 
microscopical  examination,  were  found  to  be  malignant 
Subsequently  there  was  a  reappearance  of  the  growth 
higher  up  along  the  side  of  the  trachea,  and  in  the  glands 
by  tfie  side  of  the  sterno-cleido-mastoid  muscle.  The 
patient  is  now  dying  of  gradual  suffocation  and  asthe^ 


ma. 


The  President  regarded  the  prognosis  in  Dr.  North- 
rup's  case  as  exceedmgly  bad. 

Dr.  Wyeth  regarded  the  presence  of  giant  cells  |as 
special  to  sarcomatous  and  tubercular  tissue.  While  it 
was  not  generally  conceded,  he  nevertheless  believed  it  to 
be  true  that  sarcoma  never  exists  without  the  presence 
of  giant  cells. 

Dr.  Northrup  did  not  regard  the  arrangement  of  the 
tissue  as  either  tubercular  or  sarcomatous,  and  thought 
that  the  giant  cells  belonged  to  granulation  tissue. 

Dr.  Wyeth  said  it  had  been  unusual  in  his  experience 
to  see  such  a  growth -of  giant  cells  in  granulation  tissue. 

Dr.  a.  B.  Robinson  remarked  that  giant  cells  were  of 
common  occurrence  in  granulation  tissue,  especially  the 
more  chronic  forms  of  inflammation. 

The  President  remarked  that  clinically  these  growths 
were  followed  by  secondary  development  of  carcinoma, 
even  though  it  was  a  chronic  abscess.  He  should  rec- 
ommend, under  such  circumstances,  removal  of  all  the 
indurated  tissue  and  all  the  enlarged  glands  from  the 
axilla. 

Dr.  Wyeth  thought  that  all  enlarged  glands  in  all 
operations  for  removal  of  tumors  from  the  breasts  should 
be  removed. 

ULCERATIVE   ENDOCARDITIS. 

Dr.  J.  Lewis  Smith  presented  a  specimen  from  a  case 
of  endocarditis,  attended  by  hemorrhages,  which  occurred 
in  the  New  York  Foundling  Asylum  during  his  service 
in  August  last.     The  following  history  was  prepared  by 

the  house-physician,  Dr.  H.  P.  Bissell :  Mamie  D , 

aged  five  and  a  half  years,  had  scarlatina  in  1882,  measles 
in  1883,  and  since  had  two  attacks  of  pneumonia.  In 
June  of  the  present  year  she  contracted  pertussis,  and  on 
August  24th  she  was  sent  to  the  hospital. 

On  August  25th  she  was  first  seen  by  Dr.  Smith.  At 
this  time  her  ajcillary  temperature  was  104^**;  tongue 
dry  and  furred ;  some  cough,  but  examination  of  the 
chest  negative. 

August  26th. — 10  A.M. :  Axillary  temperature  100°, 
slept  tolerably  well  during  the  night,  and  had  two 
alvme  evacuations  since  yesterday.  2  p.m.  :  Axillaiy 
temperature,  io2|°  ;  pulse,  160,  after  crying.  The  bowels 
are  regular;  the  face  pallid  and  anxious,  the  patient 
fretful  when  disturbed,  and  each  day  attacks  of  vomiting 
occur,  and  the  vomited  matter  presents  the  ordinary  ap- 
pearance. Dr.  Smith  examined  the  patient  thoroughly. 
The  action  of  the  heart  though  rapid  was  accompanied 
by  no  perceptible  abnormal  sounds,  and  the  urine,  tested 
by  heat  and  nitric  acid,  was  found  free  from  albumen. 
From  the  history  and  appearance  of  the  child,  especially 
from  its  pallor,  anxious  features,  and  the  persistent  hack- 
ing cough  which  closely  followed  the  cough  of  pertussis, 
Dr.  Smith  believed  that  the  case  was  one  of  acute  miliaiy 
'tuberculosis,  though  the  possibility  of  its  being  typhoid 
fever  was  considered.  Three  grains  of  quinipe  were 
given  every  six  hours.  Between  5  and  7  p.m.  she  had  a 
copious  evacuation  from  the  bowels  of  very  black  blood, 
which  strengthened  the  suspicion  that  the  disease  might 
be  typhoid  fever. 

August  27th. — 10  A.M. :  Temperature,  axillary,  102°  j 
pulse,  160 ;  has  vomited  often  since  yesterday,  but  no 
blood.  An  enema  of  hot  water  was  given  last  night, 
since  which  no  bloody  stool  has  occurred.    2  P.M. :  Tem- 


November  15,  1884.] 


THE  MEDICAL  RECORD, 


555 


perature,  axillary,  104^° ;  pulse,  168 ;  heart  carefully 
auscultated,  but  no  abnormal  sounds  noticed  ;  its  action, 
while  very  frequent,  was  strong  and  irritable,  8  p.m.  : 
Temperature,  io2|°;  pulse,  144;  had^one  normal  stool 
since  last  record  ;  has  vomited  much,  for  which  bismuth 
and  pepsine  have  been  administered. 

August  28th. — Had  one  dark  stool  since  'yesterday, 
not  bloody. 

August  30th. — 10  A.M. :  Temperature, .104° ;  pulse/150 ; 
slept  at  intervals  during  the  ni^ht ;  breathing  still  labored, 
and  sighing ;  she  takes  nourishment  readily  and  in  fair 
quantity;  physical  examination  of  chest  reveals  only 
the  abnormal  breathing.  8  p.m.  :  Temperature,  io2|** ; 
pulse,  140.  About  two  o'clock  this  afternoon  she  had  a 
passage  from  bowels,  consisting  of  about  three  table- 
spoonfuls  of  red  blood,  and  another  of  the  same  charac- 
ter, but  not  so  copious,  a  little  later.  For  these  she  was 
ordered  an  enema  of  hot  water  and  alum. 

August  31st. — 10  A,M.  :  Patient  rested  pretty  well  last 
night;  temperature,  104^°;  pulse,  160.  3.20  p.m.  :  Tem- 
peratiu-e,  io2|° ;  pulse,  150.  7  a.m.  :  Temperature, 
^^SV I  pulse,  150;  respiration,  36;  tongue  coated  and 
dry ;  some  tenderness  on  pressure  over  abdomen. 

September  ist. — 10  a,m.  :  Temperature,  102°  ;  pulse, 
144 ;  general  condition  about  the  same.  8  p.m.  :  Tem- 
perature, 103°;  pulse,  140. 

September  2d. — 8  a.m.  :  Temperature,  ioif°.  3  p.m.  : 
Temperature,  103°  ;  pulse,  140 ;  a  good  deal  of  vomiting 
to-day  ;  hands  and  feet  cold. 

September  3d. — 7  a.m.  :  Temperature,  98^°  ;  frequent 
vomiting.  11  a.m.  :  Temperature,  105  i°  ;  pulse,  168; 
head  hot,  hands  and  feet  cold.  8  p.m.  :  Constant  vom- 
iting. To-day  for  the  first  time  small  extravasations  of 
blood  were  observed  under  the  skin,  especially  over  the 
abdomen,  and  a  few  fine  rftles  were  observed  in  the  right 
side  of  the  chest,  probably  produced  by  extravasated 
blood  in  the  alveoli  of  right  lung  ;  temperature,  io2|°  ; 
pulse,  150  ;  respiration,  44. 

September  4th. — 8  a.m.  :  Patient  vomited  blood  twice 
this  morning  ;  temperature,  ioif°.  2  p.m.  :  Temperature, 
iooJ°. 

September  5th. — 9  A.M. :  Temperature,  102°. 

September  6th. — Died  at  7  a.m. 

This  patient  was  examined  by  several  physicians,  but 
to  all  of  us  the  disease  was  obscure.  Acute  miliary  tu- 
berculosis, typhoid  fever,  and  purpura  hemorrhagica  were 
considered,  but  no  positive  diagnosis  was  made. 

Autopsy^  September  6th,  nine  hours  after  death. — 
Numerous  points  of  extravasated  blood  underneath  the 
integument ;  general  paleness  of  all  the  internal  organs. 
Brain  :  Entire  right  anterior  lobe,  except  that  looking  to- 
ward the  median  line,  covered  by  extravasated  blood, 
which  filled  the  intergyral  spaces;  a  similar  extravasa- 
tion, but  less  in  extent,  over  the  right  posterior  lobe  ;  no 
points  of  extravasated  blood  noticed  in  substance  of  the 
brain ;  small  extravasations  of  blood  under  the  pleura, 
and  in  substance  of  lungs,  no  other  pulmonary  lesions ; 
similar  extravasations  underneath  the  peritoneum,  and  in 
substance  of  liver  and  spleen ;  none  observed  in  the 
kidneys,  which  may  explain  the  fact  that  the  urine  re- 
mained free  from  blood.  The  entire  gastric,  and  a  con- 
siderable part  of  the  intestinal  mucous  surface,  presented 
as  mottled  an  appearance  as  the  skin  in  measles,  due 
to  the  extravasation  of  blood  in  and  underneath  it. 

The  state  of  the  heart  was  of  chief  interest.  In  this 
organ  we  found  the  primary  disease,  to  which  all  the 
symptoms  were  referrible,  A  small  quantity  of  blood 
was  found  in  the  cavities,  but  an  oblong  fibrinous  concre- 
tion was  attached  to  the  mitral  valve  ;  its  length  three- 
fourths  of  an  inch,  its  breadth  one-third  of  an  inch.  The 
curator,  Dr.  Northrup,  will  state  the  results  of  his  exam- 
inations, which  establish  the  diagnosis  of  an  ulcerative 
endocarditis. 

This  child,  so  far  as  known,  never  had  rheumatism.  It 
is  only  of  late  years  that  ulcerative  endocarditis  has  begun 
to  attract  attention,  and  a  number  of  cases  have  been  re- 


ported. During  the  present  year  a  case  occurred  in  the 
Middlesex  Hospital,  London,  and  in  the  discussion  it  was 
proposed  to  designaLte  the  disease  septic  endocarditis. 
What  may  be  the  relation  of  micro-organisms  to  it,  I  am 
not  prepared  to  say,  but  I  believe  that  micrococci  have, 
as  a  rule,  been  found  in  abundance  upon  and  under  the 
surface  of  the  endocardium  in  those  who  have  perished 
from  this  disease.  The  contamination  of  the  blood  and 
the  infarctions  seem  to  result  entirelyj^from  the  endocar- 
ditis. 

Report  on  the  pathological  specimen  by  Dr.  W*  P* 
Northrup, — Heart  and  liver  :  From  the  margin  of  one 
cusp  of  the  mitral  valve  hangs  a  pyriform  body  about 
two  centimetres  in  length,  half  as  wid6  at  its  widest  part, 
its  pedicle  having  a  diameter  of  about  a  half  centimetre. 
On  the  contiguous  portion  of  the  opposite  cusp  is  a  nod- 
ule of  about  the  same  diameter  as  the  pedicle  of  the 
first.  Its  surface  has  a  rough,  villous  appearance.  An- 
other nodule,  much  smaller,  of  similar  appearance,  is  sit- 
uated on  one  of  the  columnae  corneae,  at  the  level  of  the 
dependent  end  of  the  adjacent  polypoid  body.  About 
six  other  small,  some  minute,  points  of  similar  appearance 
are  found  in  the  same  (the  left)  ventricle. 

Microscopic  examination  of  the  polypoid  body  shows 
nearly  all  of  it  to  be  made  up  of  fine  granular  matter, 
composed  largely  of  rod- shaped  bacteria,  coated  on  the 
surface  with  recent  fibrin  and  white  and  red  blood-cells. 
The  peduncle  fits  upon  a  cone  of  new  growth  from  the 
valve.  The  section  now  under  the  microscope  is  a  longi- 
tudinal cut  through  the  polypoid  body,  extending  also 
through  the  cone-shaped  base  into  the  substance  of  the 
valve.     In  this  section  the  whole  process  is  manifest. 

From  below  upward  we  find  four  gradations,  (i.) 
Granular  matter  of  polypus,  made  up  of  rod-shaped 
bacteria  mostly.  (2.)  At  the  margin  of  the  wart-like  ex- 
crescence a  zone  of  necrosis  showing  pus,  broken-dovm 
tissue,  etc.  (3.)  A  broader  area  of  swollen  cells,  either 
of  connective-tissue  cells  or  new  cells,  some  pus,  swollen 
and  granular  fibres.  (4.)  The  deeper  tissue  of  the 
valve  in  nearly  normal  condition. 

The  second  section  is  a  similar  view  of  the  nodule  on 
the  contiguous  portion  of  the  companion  cusp.  The 
process  here  shown  is  the  same,  though  less  advanced. 
It  shows  swollen  cells,  zone  of  necrosis,  adherent 
granular  mass  skirted  by  fresh  blood-clot.  In  both  cuts 
the  white  cells  in  the  clot  increased  markedly  in  propor- 
tion to  the  red,  especially  next  to  the  granular  matter, 
and  are  deposited  in  strata.  The  heart  muscle  and  the 
liver  were  examined.  The  liver  is  the  seat  of  moderate 
fatty  infiltration.  Neither  liver  nor  heart  muscle  show 
micrococci. 

This  case  seems  to  me,  taking  the  history  and  the 
lesions,  to  furnish  a  typical  section  of  malignant  endo- 
carditis or  acute  ulcerative  endocarditis.  There  are  no 
ulcers  showing  loss  of  substance.  The  lesion  in  this 
case  is  the  nodular  outgrowth  of  connective  tissue,  form- 
ing vegetations  on  the  margin  of  the  valve,  the  outer 
margin  becoming  ulcerated ;  upon  this  roughened  surface 
the  fibrin  accumulated  and  formed  the  polypoid  body. 
The  part  played  by  the  rod-shaped  bacteria  I  know 
nothing  of.     They  are  there  in  myriads. 

The  Society  then  went  into  executive  session. 


Prophylaxis  of  Migraine. — Dr.  Haig  reports  in 
The  Practitioner  the  case  of  a  young  man,  thirty  years  of 
age,  who  suffered  torments  from  frequent  attacks  of  hemi- 
crania,  which  ceased  entirely  after  he  adopted  a  purely 
vegetable  diet,  although  they  had  recurred  as  frequently 
as  three  times  a  week  before  that  time.  Dr.  Haig 
thought  that  possibly  the  neuralgia  was  caused  by  poison- 
ing with  ptomaines  formed  in  the  intestinal  canal  during 
the  digestion  of  meat.  After  living  upon  an  exclusively 
vegetable  diet  for  a  considerable  time  he  was  able  gradu- 
ally to  return  to  a  bill  of  fare  containing  a  small  quantity 
of  meat. 


556 


THE  MEDICAL  RECORD. 


[November  15,  1884. 


THE  NEW  YORK  ACADEMY  OF  MEDICINE. 
Stated  Meetings  November  6,  1884. 

FoRDYCE  Barker,   M.D.,  LL.D.,  President,  in  the 
Chair. 

the  pathojlogy  of  sensory  aphasia — with  a  speci- 
MEN. 

Dr.  R.  W.  Amidon  read  a  paper  based  upon  original 
observations  in  one  case,  with  a  revieiv  of  the  history  of 
twenty-three  others  reported  by  different  authors. 

The  specimen  was  accompanied  by  the  following  his- 
tory :  A  female  patient,  sixty-four  years  of  age,  married, 
had  been  in  perfect  health  up  to  nine  years  ago,  when 
she  began  to  suffer  from  flatulent  dyspepsia,  headache, 
and  other  neurasthenic  phenomena.  Six  weeks  before 
Dr.  Amidon  first  saw  her  she  was  seized  with  severe 
pain  on  the  left  side  of  the  head,  which  continued  three 
days,  when  she  became  flighty  and  excitable,  and  vomited. 

At  the  date  of  his  first  visit,  June,  1883,  the  right  pupil 
was  larger  than  the  left,  the  tongue  deviated  slightly  to 
the  right,  the  right  hand  was  not  as  much  stronger  than 
the  left  as  it  should  have  been,  and  it  was  somewhat 
tremulous.  There  was  no  weakness  of  the  right  lower 
extremity,  and  no  marked  disturbance  of  motility.  The 
fundus  oculi  was  normal,  and  acuity  of  vision  was  ap- 
parently perfect.  With  regard  to  speech,  it  was  only  in 
answering  questions  that  she  spoke  incorrectly.  She 
gave  inappropriate  answers  to  interrogatories,  she  could 
not  count,  or  say  letters,  but  when  she  spoke  of  her  own 
accord  her  remarks  were  connected  and  intelligible.  She 
knew  all  her  friends  except  her  husband,  but  called  her 
son  her  father.  She  could  not  read  and  could  not  be 
induced  to  write.  She  could  hear  well,  and  could  sing 
correctly.  She  was  subject  to  periodic  attacks  of  a  spas- 
modic nature,  occurring  at  intervals  of  about  a  month, 
characterized  by  a  cry,  a  drawing  up  of  the  right  hand, 
and  drawing  of  the  mouth  to  the  right,  followed  by 
general  convulsions,  sometimes  with  involuntary  evacua- 
tions. P'ebruary  15,  1884,  she  was  seized  with  a  convul- 
sion at  7  P.M.  which  continued  until  11  a.m  the  i6th, 
when  she  became  comatose  and  in  this  condition  died. 
Her  family  stated  that  during  the  last  twenty-four  hours 
of  life  she  passed  very  little  urine. 

At  the  autopsy  the  kidneys  were  found  to  be  the  seat 
of  advanced  interstitial  changes. 

The  right  cerebral  hemisphere  was  normal.  On  the 
left  side  there  was  an  irregular  depression,  with  destruc- 
tion of  the  cortex  by  softening,  involving  the  inferior 
parietal  lobule,  the  angular  gyrus,  the  second  occipital 
and  the  first  temporal  convolutions.  There  were  athero- 
matous changes  in  the  vessels  supplying  these  parts,  one 
of  them  being  entirely  occluded. 

Dr.  Amidon  then  presented  eight  diagrams  and  read 
the  histories  of  cases  reported  by  Balzer,  d'Heilly,  and 
Chautemesse,  A.  B.  Ball,  Chauflfard,  Giraudeau,  SeppiUi, 
and  others. 

Of  the  twenty-four  cases,  in  eight  with  lesions  affecting 
the  visual  and  the  auditory  regions  of  the  left  hemisphere 
there  was  both  word-blindness  and  deafness ;  in  two  in 
which  the  area  of  vision  alone  was  affected  there  was 
word-blindness ;  in  fourteen  with  the  lesion  in  the  audi- 
tory region  there  was  word-deafness. 

Dr.  Amidon  drew  the  following  conclusions  :  Word- 
blindness  is  an  incapacity  to  understand  speech,  written 
or  printed,  vision  and  intelligence  being  preserved.  It 
is  generally  dependent  upon  a  destructive  lesion  of  parts 
of  the  inferior  parietal,  middle,  angular  gyrus,  and  second 
occipital  convolutions  of  the  left  side.  Its  mechanism 
consists  of  an  abolition  of  the  transformation  of  written 
words  into  visual  verbal  images. 

Seppilli's  conclusions  were  that  word-deafness  was  a 
lesion  of  speech  clinically  and  anatomically  distinct  from 
aphasia.  It  was  often  associated  with  amnesic  or  motor 
aphasia,  or  with  word-blindness.     The  lesion  of  word- 


deafness  consisted  in  destruction  of  the  first  and  second 
left  temporal  convolutions.  Its  mechanism  consisted  in 
abolition  of  transformation  of  spoken  words  into  verbal 
images.  He  considered  word-deafness  of  great  value  in 
locating  a  lesion  of  the  left  temporal  lobe. 

Dr.  Frank  H.  Hamilton  then  read  a  paper  entitled ' 

THE   ASIATIC    CHOLERA     AT     SUSPENSION    BRIDGE,    1854, 
AND    ITS    LESSONS — WHAT  WE   KNOW  OF  CHOLERA. 

The  paper  was  the  fulfilment  of  a  promise  made  to 
the  editor  of  the  Buffalo  Medical  Journal  in  1854,  to 
write  a  paper,  some  time,  on  the  Asiatic  cholera  as  it  pre- 
vailed at  Suspension  Bridge  that  year.  After  directing 
attention  to  the  extreme  fatality  of  the  epidemic  and  its 
rapid  spread  among  the  workmen  at  Suspension  Bridge, 
the  author  ascribed  the  great  mortality  to  the  elevated 
temperature,  moisture  of  the  ground,  and  alluvial,  re- 
cently upturned  soil  It  was  at  the  request  of  Dr.  Rogers 
that  Dr.  Hamilton  and  two  other  physicians  visited  the 
patients  during  this  epidemic  The  following  lessons 
which  he  had  drawn  from  it  were  not  presented  as  new, 
but  as  being  entitled  to  special  notice  in  view  of  the  fact 
that  we  were  liable  to  have  cholera  imported  into  this 
city  at  any  time.  His  opinions  would  be  expressed 
chiefly  upon  the  question  of  what  is  the  present  state  of 
knowledge  of  the  nature,  the  etiology,  the  mode  of  prop- 
agation, and  the  treatment  of  Asiatic  cholera. 

First,  Dr.  Hamilton  claimed  that  we  had  no  positive 
knowledge  of  the  existence  of  a  specific  cholera  germ. 
In  1854  an  Italian  |physician  described  a  germ  to  the 
presence  of  which  he  ascribed  the  development  of 
cholera.  Recently  Koch  had  discovered  the  comma- 
bacillus,  which  he  regarded  as  the  true  cholera  germ,  but 
after  reviewing  the  facts  for  and  against  Koch's  views, 
and  the  observations  of  others  who  had  investigated  the 
subject,  the  author  stated  that  in  view  of  the  conflicting 
testimony  with  regard  to  the  theory  of  Koch  that  the 
comma-bacillus  was  the  cause  of  cholera,  we  were  justified 
in  the  assertion  that  the  claim  had  not  been  established.^ 

Even  if  it  were  determined  that  the  comma-bacillus  was 
always  present  in  cholera  and  never  in  otner  disease  or 
in  health,  it  would  not  be  certain  that  the  bacillus  and 
cholera  stood  in  the  relation  of  cause  and  effect. 

Again,  the  theory  was  also  defective  in  that  it  had  not 
been  shown  that  the  introduction  of  this  germ  into  the 
animal  system  would  produce  cholera.  The  inoculations 
by  Koch  himself,  practised  upon  the  lower  animals,  had 
been  barren  of  results. 

Again,  if  it  were  established  that  a  microbe  was  the 
cause  of  cholera,  the  question  would  remain  to  be  an- 
swered, which  of  the  microbes  hitherto  described,  or  yet 
to  be  discovered,  would  prove  the  efficient  agent.  But 
it  might  still  remain  to  be  proven,  should  the  experi- 
mentalists succeed  in  producing  cholera  by  the  introduc- 
tion of  a  fluid  containing  a  germ  or  germs  into  the  sys- 
tem, whether  the  efl&cient  agent  were  the  fluid  or  the 
germ.  It  might  be  the  fluid  containing  the  microbe 
which  was  the  cause  of  cholera,  this  fluid  having  taken 
on  properties  which  no  microscope  could  detect.  The 
author  did  not  wish  to  be  understood  as  underestimating 
the  importance  of  microscopical  studies ;  much  useful  in- 
formation had  been  derived  from  the  microscope  in  the 
study  of  disease  ;  but  so  far  as  the  cholera  or  other  epi- 
demic infectious  diseases  were  concerned  microscopists 
had  not  taught  us  any  important  lessons  either  with 
regard  to  their  cause  or  their  prevention.  Germicides 
kill  the  microbes  when  attacked  outside  of  the  body,  out- 
side of  their  native  soil,  but  within  the  body  these  rem- 
edies had  no  effect  upon  them.  Consequently,  patients 
continued  to  die  of  cholera  after  the  discovery  of  microbes. 
Again,  it  had  not  been  positively  proven  that  the  active 
agent  in  the  production  of  the  disease  resided  in  the  in- 
testines ;  the  symptoms  would  indicate  that  it  might  also 
exist  in  the  blood. 

The  cholera  germ,  using  this  term  in  its  general  signifi- 
cation, might  be  conveyed  firom  place  to  place  by  the 


November  15,  1884.] 


THE  MEDICAL  RECORD, 


557 


dothing  or  any  other  textile  fabric,  by  articles  of  food  or 
water,  or  animate  or  inanimate  substance.  It  might  be 
conveyed  a  considerable  distance  by  the  air — ^how  far  it 
would  be  difficult  to  say ;  probably  much  would  depend 
upon  the  force  of  the  wind  and  other  atmospheric  con- 
ditions. He  had  reason  to  think  it  could  not  be  thus 
conveyed  farther  than  a  mile  or  two.  The  theory  of 
Koch,  that  the  germ  only  found  its  way  into  the  system 
through  the  mouth  and  stomach,  was  corollary  to  his 
theory  of  causation  by  the  comma-bacillus,  and  that  in- 
troduction of  the  poison  through  the  mouth  and  into  the 
stomach  might  be  one  of  the  means  of  propagation  could 
be  admitted,  but  that  it  was  the  only  means  the  history 
of  epidemics  showed  not  to  be  true. 

It  was  not  necessary  to  assume  that  because  the  in- 
testinal secretions  were  changed,  or  the  mucous  mem- 
brane congested,  that  the  virus  was  originally  implanted 
in  the  intestinal  canal  The  blood  and  the  renal  secre- 
tion also  underwent  changes  quite  as  marked  as  those 
which  took  place  in  the  intestinal  secretions. 

Although  the  cholera  virus  were  received  into   the 
human   system  it  need  not    necessarily  give    rise    to 
cholera.     It  seemed  probable  that  every  person  living  in 
a  cholera  atmosphere  received  more  or  less  of  the  virus 
into  the  system,  but  only  a  small  proportion  of  these 
persons  took  sick  and  died     It  was  true  of  all  the  in- 
fectious diseases  that  the  reception  of  the  virus  into  the 
system  did  not  necessarily  produce  that  specific  disease. 
It  was  also  true,  however,  that  a  large  proportion  of 
those  exposed  to  infectious  diseases  became  infected, 
whereas  only  a  small  proportion  of  those  exposed  to 
cholera  took  the  disease.     A  suitable  soil  was  necessary. 
Cholera  also  differed  from  other  infectious  maladies  m 
that  one  attack  did  not  insure  protection  against  another. 
The  conditions  which  protected  against  cholera  were 
all  those  which  went  to  prevent  disturbance  of  the  ali- 
mentary canal ;  also  the  avoidance  of  impure  air,  over- 
crowding, bad  ventilation,  decaying  vegetable  or  animal 
matter,  stagnant  water,  a  warm  and  moist  condition  of 
the  atmosphere.     The  most  efficient  agent  for  the  propa- 
gation of  the  disease  seemed  to  be  the  vapors  rising  from 
newly  exposed  soil,  and  decaying  animal  and  vegetable 
matter,   together  with  a  warm  and  moist  atmosphere. 
That  filth  was  not  the  only  efficient  cause  of  the  spread 
of  the  disease  was  shown  by  the  fact  that,  during  the  epi- 
demic at  Buffalo,  those  persons  living  in  dirty  shanties  on 
a  sandy  soil  by  the  lake  escaped.     But  there  were  in- 
stances on  record  which  went  to  show  that  a  favorable 
condition  of  the  soil  and  atmosphere  alone  would  not 
check  the  spread  of  the  disease,  if  other  local  conditions 
sufficiently  favored  its  spread. 

The  profe.ssion  had  long  sought  for  a  specific  against 
Asiatic  cholera,  but  there  were  really  but  very  few 
specifics  against  any  diseases,  and  none  had  yet  been 
found  for  infectious  diseases.  But  in  the  case  of  scarlet 
fever,  etc.,  the  disease  would  run  a  certain  course,  and 
we  could  only  seek  to  conduct  the  case  to  a  favorable 
issue,  whereas  in  cholera,  if  we  took  it  in  time  we  could 
often  abort  it.  It  was  seldom,  however,  that  a  patient 
was  saved  to  whom  remedies  were  not  administered 
until  after  the  period  of  collapse  had  arrived.  The 
remedies  which  had  proven  most  successful  were  those 
which  had  long  been  known  to  be  most  successful  in  the 
treatment  of  diarrhoea,  cholera  morbus,  and  analogous 
affections.  The  most  efficient  means  prior  to  the  stage 
of  collapse  were  opium  and  rest.  Dr.  Hamilton  pre- 
ferred opium  in  the  solid  form  to  morphine.  The  patient 
would  be  more  likely  to  recover  were  he  removed  to  a 
region  not  favoring  the  propagation  of  cholera,  and 
usually  it  would  be  found  that  the  disease  would  not  be 
spread  in  his  new  domicile. 

It  was  believed  that  the  cholera  was  brought  to  Sus- 
pension Bridge  by  some  immigrants,  but  these  people  did 
not,  so  far  as  was  known,  suffer  from  the  disease  either 
before  their  appearance  at  Suspension  Bridge  or  after 
their  departure,  which  went   to   prove   that  the  rapid 


spread  and  fatality  of  the  affection  among  the  laborers 
there  was  due  to  the  condition  of  the  soil  and  atmo- 
sphere. Again,  in  only  a  few  instances,  and  in  which 
the  topographical  conditions  were  favorable,  was  the 
cholera  virus  carried  to  and  spread  in  neighboring 
localities. 

Should  cholera  appear  in  this  city,  would  it  prove  as 
fatal  as  it  had  done  in  Naples  and  the  South  of  France  ? 
Dr.  Hamilton  answered  in  the  negative,  and  for  the 
reason  that  our  climate  is  more  favorable,  our  system  of 
sewerage  better,  and  we  had  efficient  sanitar}'  measures 
for  the  prevention  of  the  spread  of  the  disease.  He  re- 
ferred to  the  success  attending  the  efforts  of  the  Sanitary 
Commission  in  stamping  out  cholera  from  Black  well's 
Island  in  1866,  and  spoke  of  the  efficient  work  done  by 
Dr.  Yale,  then  one  of  the  house-staff. 

Dr.  L.  M.  Yale  said  that  his  own  experience  with 
cholera  had  been  confined  to  the  epidemic  on  Black- 
well's  Island  referred  to  by  the  author  of  the  paper. 
The  report  which  he  then  made  included  also  the  ex- 
perience of  his  associates  upon  the  Island. 

The  epidemic  broke  out  at  the  workhouse.  It  had 
been  preceded  by  a  period  of  great  heat  and  also  the 
prevalence  of  diarrhoeal  troubles  throughout  the  Island. 
It  became  necessary,  therefore,  to  put  diarrhoeal  reme- 
dies in  various  parts  of  the  buildings,  so  that  the  patients 
could  get  them  without  the  trouble  always  of  searching 
for  a  physician. 

The  water-supply  for  a  time  was  cut  off,  owing  to  some 
defect  in  the  system  of  supply,  and  the  bread  bad  been 
sour  for  a  short  time. 

The  first  case  of  Asiatic  cholera  occurred  in  the  work- 
house, although  there  had  before  been  some  cases  of  spo- 
radic cholera  in  Charity  Hospital.  By  the  third  day  after 
the  appearance  of  the  first  case  Dr.  Yale  had  thirty-three 
cases — twenty-three  of  which  proved  fatal — ^and  about 
twenty  per  cent,  of  the  entire  number  of  inmates  were 
carried  off  before  the  disease  was  checked.  The  epi- 
demic occurred  principally  on  the  lowest  ground  of  the 
island.  More  women  contracted  the  disease  than  men, 
and  this  might  be  accounted  for  by  the  fact  that  the 
men  went  out  to  work  by  day,  and  their  wards  were 
larger;  the  women  remained  in  the  wards,  and  the 
evacuations  stood  hi  a  tub  in  a  room  where  the  inmates 
often  remained  for  a  considerable  time  in  conversation 
with  one  another. 

Again,  the  patients,  being  unwilling  to  go  to  the 
cholera  hospital,  tried  to  conceal  the  fact  when  they 
were  seized  with  diarrhoea.  These  faulty  conditions  hav- 
ing been  corrected,  the  cholera  was  rapidly  and  perma-, 
nently  stamped  out. 

Dr.  Yale  mentioned  one  circumstance  which  was  not 
easily  explainable ;  namely,  that  in  one  pavilion  as  many 
as  thirty  cases  of  cholera  developed ;  whereas  in  another 
pavilion,  not  thirty  feet  distant,  not  a  single  case  oc- 
curred, although  the  conditions,  so  far  as  could  be  ob- 
served, were  no  better  in  the  one  than  in  the  other. 

Dr.  Francis  Delafield  said  he  supposed  all  would 
admit  that  cholera  belonged  among  the  infectious  dis- 
eases, or  a  class  of  diseases  which  did  not  develop  unless 
the  human  body  were  infected  by  a  specific  poison.  No 
matter  how  bad  the  influences  under  which  human  beings 
lived  with  regard  to  soil,  food,  and  hygiene  in  general, 
they  might  develop  many  other  diseases,  but  they  would 
not  develop  cholera  unless  there  were  added  to  these 
other  favoring  conditions  the  specific  poison  that  be- 
longed to  the  disease.  Whether  that  specific  poison  had 
always  to  be  imported  into  new  regions  to  develop  the 
cholera,  or  whether  it  were  capable  of  originating  in  new 
regions,  might  be  a  subject  of  dispute,  but  experience 
seemed  to  show  that  its  home  was  India,  and  that  other 
regions  did  not  suffer  until  the  poison  was  imported. 

It  being  admitted  that  the  disease  was  due  to  a  spe- 
cific poison,  the  question  came  up,  What  is  that  poison  ? 
Here  we  have  had  all  varieties  of  theories,  none  of  which 
have  proven  particularly  satisfactory.     The  latest  theory, 


558 


THE  MEDICAL  RECORD. 


[November  15,  1884. 


to  which  attention  had  been  called  this  evening,  was  that, 
in  accordance  with  the  prevalent  doctrine  of  the  times, 
most  of  the  infectious  diseases  are  due  to  the  pres- 
ence and  growth  of  certain  minute  organisms.  Fashions 
of  this  kind  in  science  and  in  medicine  sometimes  prove 
good,  and  sometimes  prove  bad ;  and  whether  a  given 
fashion  will  prove  the  one  way  or  the  other  could  be 
known  only  after  the  lapse  of  some  period  of  time.  Dr. 
Hamilton  had  stated  very  fairly  the  evidence  for  and 
against  this  view  of  the  causation  of  cholera.  He  had 
not  stated,  however,  what  Dr.  Delafield  considered  par- 
ticularly important  to  be  borne  in  mind,  namely,  that 
there  were  only  a  very  few  men  whose  testimony  was  of 
any  value  in  speaking  of  the  presence  or  absence  of 
germs  in  disease,  and  the  reason  was  the  very  great  diffi- 
culty attending  the  manipulations  incident  to  the  proper 
performance  of  the  experiments. 

Dr.  Hamilton  had  called  attention  to  the  very  impor- 
,  tant  point  of  the  bearing  which  the  condition  of  the  soil 
-and  hygiene  had  upon  the  development  of  cholera,  and 
this  might  be  briefly  expressed  in  this  way :  Whatever 
conditions  of  air,  of  temperature,  of  soil,  of  food,  and  of 
general  hygiene  would  predispose  to  the  development  of 
diarrhoea  would  also  predispose  to  the  spread  of  cholera. 
In  other  words,  wherever  there  was  present  a  predisposi- 
tion to  diarrhoea  and  also  the  specific  poison  of  cholera 
we  would  have  cholera  developed  in  its  worst  form  and 
to  the  widest  extent.  If  all  these  predisposing  condi- 
dons  are  absent,  then  the  cholera  germ  may  find  its  way 
to  the  place  and  not  produce  cholera  at  all. 

This  seemed  to  bring  us  to  the  means  by  which  we  can 
prevent  the  spread  of  cholera.  In  the  present  state  of 
civilized  society,  quarantine  measures  seemed  to  prove 
useless  if  commercial  relations  were  to  be  continued  with 
other  countries.  What  we  should  do  was  to  seek  to 
remove  all  the  conditions  which  favor  the  development  of 
•the  disease. 

Dr.  a.  L.  Loomis  said  that  his  personal  experience 
with  cholera  had  been  limited  to  a  few  cases  which  he 
.saw  in  this  city  in  1866-67,  and  he  had  therefore  felt, 
when  requested  to  discuss  the  paper,  that  he  was  largely 
in  the  position  of  one  who  was  simply  a  student  of  the 
literature  of  the  subject. 

It  seemed  that,  at  the  present  time,  we  might  justly 
divide  the  infectious  diseases  into  three  classes,  according 
to  the  nature  of  their  specific  causes. 

The  specific  cause  in  the  one  class  produced  its  dis- 
ease on  being  transmitted  to  the  well  person  directly 
-from  one  already  infected.  There  was  no  evidence  that 
the  exanthematous  diseases  were  transmitted  in  any 
other  way  than  by  direct  or  indirect  exposure  to  the  con- 
tagion. 

The  second  class  was  that  in  which  the  disease  was 
due  t  o  exposure  to  a  poison  developed  outside  of  the 
.human  body,  as  decomposing  or^nic  matter. 

The  third  class  was  that  in  which  the  poison  developed 
within  the  living  organism,  or  one  affected  with  the  dis- 
ease, and  was  capable  of  reproducing  the  disease  only 
when  it  had  undergone  certain  changes  after  its  discharge 
^r  removal  from  the  infected  person.  To  this  ckSs 
(belonged  typhoid  fever,  and  cholera,  as  Dr.  Loomis  be- 
lieved from  his  study  of  the  literature  of  the  subject.  The 
home  of  cholera  seemed  to  be  Bengal,  and  epidemics  in 
x>ther  parts  of  the  world  could  always  be  traced  as  having 
x>riginated  there.  He  did  not  believe  that  cholera  was 
ever  of  spontaneous  origin.  Dr.  Loomis  then  gave 
instances  which  went  to  show  that  in  every  epidemic  of 
>the  disease  its  origin  could  be  traced  to  spread  of  the 
contagion  through  soiled  clothing,  infected  water,  etc. 
The  view  that  the  poison  was  active  only  after  it  had 
•undergone  certain  changes  on  being  removed  from  the 
human  organism  was  favored  by  the  fact  that  those  mak- 
ing autopsies,  those  attending  the  patients,  and  micro- 
scopical observers  of  the  fresh  discharges,  seldom  con- 
tracted the  disease.  He  was  of  the  opinion  that  the 
poison  entered  the  body  only  through  the  mucous  mem- 


brane>  but  not  necessarily  by  way  of  the  mouth  and 
stomach. 

Sufficiently  strict  quarantine  relations  would  prevent 
the  spread  of  cholera,  but  the  difficulty  of  establishing 
such  quarantine  had  already  been  mentioned.  The 
efficacy  of  the  treatment  spoken  of  by  the  author  of  the 
paper  had  been  of  great  interest  to  him. 

Dr.  John  C.  Peters  showed  maps  illustrating  the 
spread  of  cholera  from  its  home  in  India,  and  speaking  of 
preventing  an  epidemic  in  this  country  by  quarantine, 
said  that  so  long  as  Denmark  enforced  her  quarantine 
relations  she  had  escaped  from  cholera,  whereas  as  soon 
as  those  restrictions  on  one  occasion  had  been  removed 
the  disease  poison  was  imported,  and  she,  with  many 
other  cities  of  neighboring  countries,  had  many  inhabi- 
tants  perish.  Quarantine  had  also  proven  efficacious  in 
Greece. 

The  Academy  then  adjourned. 


THE  INDUCTION  COIL  AND  ITS  VARIETIES 
—A  CORRECTION. 

To  TKK  Editor  op  Ths  Mbmcal  Record. 

Sir  :  In  my  article  on  the  Induction  Coil,  etc.,  in  the 
last  issue  of  The  Record,  I  wrote,  that  if  the  subject  is 
**  presented  with  any  measure  of  clearness,  it  ought  to  be 
of  some  little  service  to  those  who  are  interested  in,  but 
have  given  little  thought  to,  the  matter."  If,  however, 
any  one,  even  though  he  be  the  veriest  expert  in  physics, 
can  make  head  or  tail  to  Fig.  2  of  said  article,  he  must 
possess  a  keenness  of  insight  quite  phenomenal.  The 
continuous  coil-induction  apparatus  is  used  by  many 
physicians  throughout  the  country,  but  its  physical,  physio- 
logical, and  therapeutical  characteristics  seem  to  be  little 
understood ;  and,  therefore,  in  this  paper  I  endeavored 
to  answer  as  concisely  and  clearly  as  possible  the  many 
questions  that  have  been  put  to  me,  both  personally  and 
by  letter.  Unfortunately,  however,  through  some  over- 
sight, neither  the  printed  matter  nor  the  cuts  were  sent 
to  me  for  revision,  and  the  result  is,  an  unintelligible  de- 
scription. A  correct  understanding  of  the  part  devoted 
to  therapeutical  considerations  hinges  upon  this  cut.  As 
soon,  therefore,  as  a  new  one  can  be  made,  and  for  the 
benefit  of  not  a  few  of  your  readers  who  are  interested 
in  this  matter,  I  trust  you  can  find  room  for  its  reinser- 
tion. A.  D.  RocicwELL,  M.D. 

NOWMBBR  8,  1884. 

OUR  LONDON  LETTER. 

*  (From  our  Special  CorrespondcnL ) 

SIR  JOSEPH  LISTER  ON  CORROSIVE  SUBLIMATE  AS  AN 
ANTISEPTIC  DRESSING — THE  HARVEIAN  ORATION — AN- 
OTHER DEATH  FROM  THE  SUCKING  OF  TRACHEOTOMY 
TUBES   IN   CASES   OF   DIPHTHERIA. 

LONDOM,  October  a  j;  1884. 

The  event  of  the  week  has  been  the  delivery  of  Sir  Joseph 
Lister's  address  on  Corrosive  Sublimate  as  a  Surgical 
Dressing.  This  event  took  place  last  Monday  at  the  first 
meeting  for  this  session  of  the  Medical  Society  of  Lon- 
don. Sir  Joseph  commenced  his  address  by  frankly  ac- 
knowledging that  he  had  had  during  the  past  twelve 
months  instances  of  failure  with  antiseptic  dressings  and 
one  fatal  case.  This  induced  him  to  turn  his  mind  seri- 
ously to  the  subject,  and  he  came  to  the  conclusion  that 
the  volatility  of  many  antiseptics  is  a  cause  of  their  inef- 
ficiency. They  are  completely  preventive  of  sepsis  when 
first  applied,  but  this  protective  influence  gradually  les- 
sens. Eucalyptus  gauze  was  very  troublesome  to  manu- 
facture properly,  and  required  great  care  both  in  the 
original  preparation  of  it  and  also  to  preserve  it  unim- 
paired aifterward.  Sir  Joseph  mentioned  incidentally 
that,  as  regards  the  carbolic  dressings,  he  had'founda  week 


I 


November  15,  1884.] 


THE  MEDICAL  RECORD. 


559 


the  limit  of  time   during  which  a  carbolic  acid  gauze 
dressing  might  be  regarded  as  effectual. 

Salicylic  acid  was  non-volatile;  iodoform  only  very 
slowly  volatilized.  Neither  of  these  had  he  found  to 
be  powerfully  germicide.  His  attention  had  therefore 
been  directed  to  corrosive  sublimate.  With  regard  to 
this  agent  numerous  experiments  were  narrated  at  length, 
as  weU  as  cases  in  which  it  had  been  successfully  applied. 
Koch's  experiments  with  this  substance  were  referred  to. 
Koch  had  found  a  solution  of  only  one  part  of  corrosive 
sublimate  in  twenty  thousand  parts  of  water  quite  suf- 
ficient to  absolutely  destroy  the  vitality  of  the  spores  of 
the  bacillus  anthracis.  One  part  of  sublimate  to  three 
hundred  thousand  of  a  solution  of  extract  of  meat  had 
been  found  by  Koch  sufficient  to  "  inhibit  "  the  action 
of  the  spores,  so  long  as  they  remained  in  it.  The  "  in- 
hibitory action,"  as  Lister  terms  it,  was,  he  said,  suffi- 
cient in  surgery. 

The  "  wood-wool  sublimate"  used  in  Germany  was, 
he  remarked,  inconveniently  bulky,  so  he  had  had  a 
gauze  prepared  containing  one  per  cent,  of  sublimate. 
This  he  had  found  suflftcient,  but  he  had  found  the  pro- 
tective (dipped  in  a  solution  of  one  in  five  hundred)  irri- 
tate the  skin.  Numerous  experiments  were  fully  described 
in  his  long  address,  but  the  result  at  which  Lister  has 
arrived  is  the  use  of  a  gauze  prepared  with  a  solution  of 
one  part  of  sublimate  in  one  hundred  parts  of  blood  serum 
from  a  horse.  The  original  precipitate  caused  by  the 
addition  of  albumen  to  a  solution  of  corrosive  sublimate 
is,  he  finds,  soluble  in  excess  of  the  albuminous  serum, 
and  the  resulting  solution  is  efficiently  antiseptic.  Two 
and  a  half  parts  of  this  solution  are  contained  in  each  part 
of  the  gauze.  Gauze  thus  prepared  has  not  caused  irri- 
tation. That  prepared  from  a  solution  of  one  part  of 
sublimate  to  fifty  of  serum  has  in  some  instances  done  so, 
but  this  has  disappeared  when  the  weaker  gauze  has  been 
substituted.  Lister  strongly  recommends  that  during  the 
first  twenty-four  hours  after  an  operation  this  gauze 
should  be  used  in  abundance  in  at  least  sixteen  layers. 
With  the  sero-sublimate  gauze  dressing  the  **  protective" 
is  not  used,  and  the  outer  wrapping  of  mackintosh  is  un- 
necessary. The  instruments  used  during  the  operation 
cannot  of  course  be  previously  soaked  in  the  solution  as 
with  carbolic  acid. 

The  annual  oration  at  the  College  of  Physicians  has 
this  year  been  delivered  by  Dr.  Russell  Reynolds.  This 
oration  has  lately  attracted  more  attention  on  account 
of  the  counter-claim  set  up  in  Italy  for  Cisalpino  as  a 
discoverer  of  the  circulation  of  the  blood.  This  claim 
was  pretty  well  overthrown  by  Dr.  George  Johnson  in 
his  Harveian  oration  of  last  year,  and  he  has  since  written 
a  pamphlet  on  the  subject,  still  more  conclusively  estab- 
lishing Harvey's  claim  to  priority.  The  present  oration 
was  chiefly  interesting  from  the  prominent  relief  into 
which  what  maybe  called  "foresight"  on  the  part  of 
Harvey  was  thrown  by  the  lecturer.  He  showed  that 
Harvey  had  some  knowledge  of  reflex  action,  even  as 
now  understood.  He  also  appeared  to  have  some  fore- 
cast of  our  present-da^  knowledge  of  the  vaso-motor 
system,  and  had  some  idea  of  the  action  of  sexual  selec- 
tion on  the  perpetuation  of  species. 

Another  instance  of  a  medical  man  acquiring  diph- 
theria with  fatal  results  firom  sucking  a  tracheotomy  tube 
on  a  diphtheritic  patient  is  reported  this  week.  Dr. 
Samuel  Rabbeth  was  the  senior  resident  medical  offi- 
cer at  the  Royal  Free  Hospital,  and  only  graduated  at 
the  University  of  London  in  November  last,  when  he 
•  obtained  the  scholarship  and  first  gold  medal  in  obstetric 
medicine.  His  death  adds  yet  another  to  the  list  of 
brilliant  careers  cut  short  prematurely.  Nearly  all  the 
newspapers  are  eulojgizing  his  memory  and  holding  him 
up  as  a  hero  to  be  imitated.  A  hero '  no  doubt  he  was, 
for  it  requires  more  courage  to  incur  such  a  risk  than  to 
rush  to  meet  death  in  scenes  of  excitement.  The  ques- 
tion, howev.er,  occurs  whether  he  ought  to  be  imitated. 
Can  it— on  any  theory  of  ethics — be  the  duty  of  a  medi- 


cal man  to  lay  down  his  life,  or  even  to  incur  the  grave 
risk  of  catching  diphtheria,  for  the  sake  of  affording  a 
moribund  patient  the  distant  chance  of  recovery  ?  Dr. 
Rabbeth's  case  illustrates  the  melancholy  fact  that  not 
only  may  a  valuable  life  be  lost,  but,  as  in  this  case,  be 
risked  in  vain  ;  for  his  patient  died  after  all.  Surely  a 
suction-apparatus  might  be  tried  by  the  operator  before 
applying  his  mouth  to  the  wound,  and,  in  hospitals,  there 
is  no  excuse  for  such  not  being  at  hand. 


OUR   PARIS   LETTER. 

(From  our  Special  Correspondent) 
ANGINA     PECTORIS     AND     ITS     TREATMENT — CHOLERA — 
HEALTH   OF   PARIS — HOSPITALS     FOR    CONTAGIOUS   DIS- 
EASES. 

Paris,  October  24,  2884. 

There  has  always  been  great  confusion,  or  rather  mis- 
apprehension, as  to  the  real  nature  or  pathology  of  that 
terrible  affection  termed  "  angina  pectoris,'*  some  looking 
upon  it  as  a  simple  neurosis  without  any  actual  disease 
of  the  heart.  Jenner,  in  1799,  considered  that  the  dis- 
ease in  question  was  caused  by  ossification  of  the  coro- 
nary arteries,  whence  the  division  into  symptomatic  and 
idiopathic  anginas.  Other  pathologists  attributed  the  dis- 
ease to  atheroma,  aortitis,  affections  of  the  heart,  aneu- 
rism of  the  aorta.  More  recently  Professors  Germain 
S6e  and  Potain  make  out  that  angina  pectoris  is  pro- 
duced by  the  constriction  or  obliteration  of  the  coronary 
arteries  which  result  in  cardiac  ischaemia.  Still  more  re- 
cently, Drs.  Lancereaux  and  Peter,  the  former  looking 
upon  the  disease  as  neuralgic,  while  the  latter  considers 
it  to  be  a  cardiac  neuritis.  Dr.  Huchard,  Physician  to 
the  Hdpital  Bichat,  in  a  work  recently  published  by  him, 
gives  his  experience  of  the  disease,  and  seems  to  favor 
the  theory  advanced  by  Professors  S^  and  Potain.  Dr. 
Huchard,  placing  the  subject  in  a  clinical  point  of  view, 
divides  the  affection  into  true  and  false^  or  into  organic 
and  functional  anginae  pectoris.  The  former  is  a  rare 
disease  and  consists  in  an  organic  alteration  of  the  coro- 
nary arteries,  producing  ischaemia  of  the  heart,  and  which, 
sooner  or  later,  almost  always  proves  fatal.  The  pseudo 
or  functional  angina  is  much  more  common,  and  is  met 
with  as  a  complication  of  other  affections,  such  as  hys- 
teria, neurasthenia,  neurosism,  exophthalmia,  arthritis, 
rheumatism,  gout,  dyspepsia,  etc.,  which  angina  is  con- 
sidered perfectly  curable.* 

As  regards  the  treatment  of  angina  pectoris.  Dr. 
Huchard  has  found  nothing  equal  to  the  nitrite  of  amyl, 
which  he  says  fulfils  the  two  principal  indications :  the 
suppression  of  pain  and  the  overcoming  the  syncope 
which  attend  the  disease. 

Dr.  Huchard  prefers  the  nitrite  of  amyl  to  anything 
else  during  a  fit.  It  acts  with  extreme  rapidity,  in  a  few 
seconds,  and  mav  thus  prevent  imminent  death.  Its  ac- 
tion is  explained  as  follows  :  It  increases  the  activity  of 
the  intra-myocardiac  circulation  in  the  cases  in  which  the 
latter  is  seriously  impeded  by  the  spasm  or  obliteration  of 
the  coronary  arteries.  Moreover,  it  acts  on  the  peripheric 
arteries  by  producing  dilatation  in  them,  and  by  thus 
diminishing  the  peripheric  resistance  it  favors  and  aug- 
ments the  ener^  of  the  central  organ  of  circulation.  Dr. 
Huchard  administers  the  nitrite  by  inhalation  in  doses  of 
three  to  six  drops,  which  is  poured  on  a  handkerchief  and 
may  be  repeated  two  or  three  times  in  the  twenty-four 
.hours.  It  is  considered  advisable  to  begin  with  the , 
minimum  dose,  that  is,  three  drops,  which  may  be  gradually 
increased  to  ten,  twelve,  fifteen,  and  even  to  twenty 
drops  at  a  time.  Dr.  Huchard  considers  the  nitro- 
glycerine and  the  nitrite  of  sodium  as  inferior  to  the 
nitrite  of  amyl  in  the  treatment  of  this  affection.  As 
adjuvants  or  preventives  the  author  attaches  great  im- 
portance to  the  employment  of  the  iodides  of  potassium 
or  sodium,  the  latter  being  the  more  preferable,  as  it  is 

1  This  form  is  also  produced  by  the  abuse  of  tobacco*  and  is  explained  by  the 
direct  influence  of  the  poison  on  the  heart  and  its  blood-vessels,  and  also  by.its 
action  on  the  nerves  of  the  heart  and  of  the  stomach. 


56o 


THE  MEDICAL   RECORD. 


[November  15,  1884. 


better  tolerated  by  the  patient.  Such  is  the  treatment 
of  the  true  angina  pectoris.  In  the  pseudo  forms,  the 
same  inhalations  combined  with  h3rpoderniic  injections 
of  morphia  may  be  usefully  employed  during  the  par- 
oxysms, and  hydrotherapy  to  prevent  recurrences  of  the 
latter.  The  treatment  appropriate  to  the  concomitant 
affections  must,  at  the  same  time,  be  rigorously  at- 
tended to. 

If  the  present  cholera  epidemic  in  this  country,  which, 
however,  is  gradually  dying  out,  has  been  disastrous  in 
one  way,  it  has  proved  beneficial  in  many  others.  It 
has  roused  the  people  to  a  sense  of  the  necessity  of  thor- 
ough sanitation,  which  I  mean  to  be  used  in  its  widest 
sense — personal,  domiciliary,  and  public.  Everywhere 
sanitation  is  the  order  of  the  day,  and  among  other  meas- 
ures the  Parisians  are  only  now  beginning  to  look  to 
their  potable  water,  and  they  now  admit  that  the  water 
they  drink  may  be  the  vehicle  of  disease-germs,  and  par- 
ticularly those  of  cholera  and  typhoid  fever,  a  fact  long 
well  known  to  them,  but  which  up  till  now  they  have 
repudiated,  simply  because  it  was  not  a  French  idea. 
The  sages  have  since  discovered  that  the  water  of  the 
Seine  is  a  great  deal  more  contaminated  than  it  was 
twenty  years  ago,  even  in  making  allowance  for  the  in- 
crease of  the  population,  and  projects  have  been  set  on 
foot  in  and  out  of  the  Academy  of  Medicine  for  its  thor- 
ough purification,  and  for  the  adoption  of  such  measures 
as  may  be  necessary  to  prevent  its  being  rendered  foul. 

Apropos  of  cholera,  Dr.  Leroy  de  M6ricourt  read  his 
report  on  the  numerous  papers  that  were  forwarded  to 
the  Paris  Academy  of  Medicine  on  the  nature  and  treat- 
ment of  cholera,  and  among  them  was  the  report  of  the 
commission  formed  by  the  Soci6t6  de  M6decine  of  Mar- 
seilles, which  concluded  that  Koch*s  theory  was  only  a 
hypothesis  without  any  foundation,  and  that  the  comma- 
bacillus  could  not  be  looked  upon  as  the  specific  agent 
of  cholera. 

Paris  is  in  a  remarkably  healthy  state  at  the  present 
time.  It  is  free  from  epidemics  of  any  kind,  and  even 
typhoid  fever,  which  is  generally  so  prevalent  in  spring 
and  autumn,  has  been  raging  with  less  severity  than  it 
has  done  for  many  years  previously,  the  number  of  deaths 
during  the  last  two  weeks  being  fewer  than  that  shown  in 
any  previous  weekly  report  of  this  year. 

The  Council  of  Hygiene  and  of  Salubrity  of  the  Seine 
has  proposed  the  creation  in  Paris  of  refuge-houses  where, 
in  case  of  the  occurrence  of  croup  or  any  other  con- 
tagious malady  among  children,  parents  could  remove 
them  at  once.  They  will  there  be  properly  cared  for 
until  they  have  completely  recovered,  and  thus  prevent 
further  contagion  among  other  members  of  the  family. 


Official List€f  Changes  in  the  Staiiotu  arndDuHss  ef  Offiars 
serving  in  the  Medical  Department^  United  States  Army^ 
from  November  2  to  November  8,  1884. 

Spencer,  W.  C,  Major  and  Surgeon.  Ordered  to 
Fort  Trumbull,  Connecticut,  for  duty  as  Post  Surgeon, 
relieving  Assisilint  Surgeon  William  J.  Wilson,  U.  S.  A., 
who  will  report  at  Department  Headquarters  and  await 
further  orders.  S.  O.  227,  Department  of  the  East, 
November  5,  1884. 

CoRBissiER,  W.  H.,  Captain  and  Assistant  Surgeon. 
Ordered  to  Fort  Grant,  A.  T.,  for  duty  as  Post  Surgeon. 
S,  O.  102,  Department  of  Arizona,  October  30,  1884. 

Hopkins,  William  E.,  First  Lieutenant  and  Assistant 
Surgeon.  Ordered  to  Fort  Lowell,  A.  T.,  for  duty  as 
Post  Surgeon.  S.  O.  102,  Department  of  Arizona,  Octo- 
ber 30,  1884. 

Egan,  Peter  R.,  First  Lieutenant  and  Assistant  Sur- 
geon. Relieved  from  duty  at  Fort  Lowell,  A.  T.,  and 
ordered  to  Fort  Bowie,  A.  T.,  for  duty  as  Post  Surgeon. 
S.  O.  102,  Department  of  Arizona,  October  30,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  November  8, 1884. 

Craig,  Thomas  C,  Passed  Assistant  Surgeon.  To 
the  Alliance  for  temporary  duty.     November  i,  1884. 

Swan,  Robert,  Passed  Assistant  Surgeon.  Detached 
from  the  Naval  Hospital,  Norfolk,  Va.,.and  placed  on 
sick  leave.     November  3,  1884. 

WiEBER,  F.  W.  F.  Appointed  Assistant  Surgeon. 
November  3,  1884. 


^jedical  Items. 


Contagious  Diseases — ^Weekly  Statement.— Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  November  8,  1884 : 


Week  Boding 


Cases. 

November  i,  1884 
November  8,  1884 

Deaths, 
November  1,  1884 
November  8,  1884 


I 


A  Fresh-Air  Supply  for  Cities. — A  writer  in  the 
Journal  de  Midecine  de  Paris  advances  the  curious  prop- 
osition of  furnishing  all  large  cities  with  an  abundance 
of  fresh  country  air  just  as  they  are  now  supplied  with 
gas  and  water.  He  draws  a  vivid  picture  of  the  count- 
less benefits  that  would  follow*  from  the  general  adoption 
of  such  a  plan.  The  sick  and  the  debilitated  would  re- 
gain health  and  strength,  while  the  capacity  of  city 
dwellers  for  intellectual  and  physical  labor  would  be 
greatly  increased.  The  method  proposed  is  simple 
enough.  A  large  open  field  is  to  be  chosen  in  the 
country  and  this  is  to  be  surrounded  with  a  high  wall  and 
planted  around  with  balsamic  trees  so  as  to  filter  the  air 
from  dust.  Then  by  means  of  an  immense  fan  the  air  is  to 
be  forced  through  a  large  conduit  and  distributed  through 
smaller  pipes  to  the  chambers  in  the  dwellings  and  other 
buildings  in  the  city.  In  summer  the  air  could  be  cooled 
and  in  winter  warmed  before  entering  the  houses.  The 
imaginative  writer  calculates  that  by  means  of  a  turbi- 
nated wheel  three  metres  in  diameter  and  a  twelve-horse- 
power engine^  120,000  cubic  metres  of  air  could  be  de- 
livered to  the  city  every  hour.  Such  an  atmospheric  rus 
in  urbe  would  be  very  charming,  and  so  doubtless  would 
be  the  odor  of  this  once  pure  air  after  it  had  traversed 
several  miles  of  city  soil  in  company  with  the  sewers  and 
the  gas-pipes. 

Temporary  Preservation  of  Post-mortem  Spec 
MENS. — In  the  second  number  of  The  Asclepictd^  among 
the  Opuscula  Practica,  Dr.  Richardson  describes  a 
method  of  temporarily  preserving  specimens  taken  from 
the  dead  body.  A  wide-mouthed  bottle,  with  a  large 
stopper,  which  is  made  to  fit  evenly  by  the  use  of  a  litUe 
glycerin,  is  filled  with  a  mixture  of  common  coal-gas  and 
one  drachm  of  ammoniated  chloroform.  The  stopper  is 
then  tied  down.  Any  part  which  is  desired  to  be  pre- 
served is  placed  in  a  fold  of  soft  muslin  and  gently  pressed 
so  as  to  remove  superfluous  fluid.  The  next  point  is  to 
introduce  the  part  enveloped  in  the  muslin  into  the  bot- 
tle without  displacing  more  of  the  gaseous  contents  than 
necessary.  The  ammoniated  chloroform  is  supposed  **  to 
prevent  the  breaking'up  of  the  water  of  the  tissues,"  and 
the  carbon  monoxide  of  the  coal-gas  preserves  the  color 
of  the  specimen. — Lancet. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  a6,  No.  21 


New  York,  November  22,  1884 


Whole  No.  73S 


ilhrigitmX  Ji^rtijcIcB. 


SOME  MORE  EXPERIENCES  WITH  JEQUIRITY. 
By  CHARLES  SOHNLIN,  M.D., 

ST.  PAUL,  MINN. 

Not  many  new  remedies  produced  such  an  excitement 
as  the  jequirity  did,  but  like  every  newcomer  it  had,  and 
has  still,  to  struggle  hard  before  it  gets  the  recognition 
which  it  merits.  The  opinions  of  the  authors  are  still 
now  divided :  some  of  them  praise  it  as  one  of  the  great- 
est remedies,  others  condemn  it  altogether,  and  a  third 
class  of  authors  keep  quiet,  waiting  for  what  will  be 
the  end  of  the  fight.  What  we  want  is  the  publication 
q{  some  more  clinical  observations,  sine  studio  et  ira,  but 
with  a  more  special  description  of  the  peculiarities  of  the 
cases. 

Let  us  first  look  over  a  little  the  clinical  experiences 
of  some  authors.  After  a  few  favorable  reports  a  great 
deal  of  opposition  was  made  by  DenefFe,  of  Ghent. 
He  says  he  never  got  a  good  result,  but  he  saw  in  one 
case  a  simple  vascular  keratitis  becoming  a  pannus  cras- 
sus,  and  he  had  in  one  case  a  perforation  of  the  cornea. 
He  always  maintained  the  inoculation  of  gonorrhoeic  virus, 
and  does  not  think  the  jequirity  has  any  advantages  over 
it ;  on  the  contrary,  he  thinks  the  effect  of  the  jequirity  is 
transient,  while  the  inoculation  of  the  gonorrhoeic  virus 
produces  a  permanent  cure. 

But  about  the  same  time  Dr.  Peschel,  of  Turin,  pub- 
lished first  twenty-two  and  then  about  eighty  full  cures 
with  jequirity,  without  any  failures  or  any  accidents.  He 
had  only  to  produce  the  inflammation  several  times,  then 
the  eye  healed  up  completely.  Twice  he  met  a  slight 
infiltration  of  the  cornea  which  quickly  healed. 

In  this  country  the  jequirity  was  first  tried  by  Dr. 
Omening,  of  New  York,  who  published  two  favorable 
cases  in  The  Record,  February  lo  and  March  17, 1883. 
After  this  Dr.  Feck  published  five  first-class  results,  and 
twelve  cases  succeeding  in  a  less  degree.  He  never  had 
a  bad  accident  to  the  cornea,  only  some  transient  des- 
quamation. Also  Dr.  Hotz,  of  Chicago,  Dr.  Standish,  of 
Boston,  myself,  and  others  published  some  very  good  re- 
sults with  jequirity.  Dr.  Landesberg,  of  Philadelphia, 
treated  9  cases,  but  had  in  5  cases  no  result,  in  2  cases 
a  bad  inflammation  of  the  cornea,  and  in  i  case  a  pan- 
ophthalmitis. 

Some  bad  results  were  also  published  in  Spain.  Dr. 
Osio  lost  three  eyes  by  panophthalmitis,  and  had  one 
case  of  perforation  of  the  cornea  and  one  case  of  a  large 
leucoma.  Dr.  Chiralt,  another  Spanish  oculist,  had  only 
favorable  results. 

The   Russians  like  the  jequirity  :    Dr.  Adamyk,  Dr. 

Schmidt  (40  cases).  Dr.  Maklakow  (10  cases),  and  others. 

In  Algiers  Dr.  S6dan  had,  under  16  cases,  3  full  cures, 

7  cases  were  improved,  6  remained  unchanged,  and  in 

one  case  he  had  a  bad  afiection  of  the  cornea. 

In  Italy,  besides  Dr.  Peschel,  also  Dr.  Mazza,  Dr. 
Ponti,  'Dr.  Guaita,  Dr.  Manfredi,  and  others,  had  some 
first-class  results.  They  could  not  cure  all  their  patients, 
but  a  great  many  of  them.  Dr.  Manfredi  had  some  bad 
accidents,  he  lost  three  eyes,  but,  as  he  says  himself,  by 
the  use  of  too  strong  infusions  of  jequirity. 

On  January  28,  1884,  there  was  in  the  French  Society 
of  Ophthalmology  a  very  instructive  discussion  about  je- 


quirity, which  is  especially  interesting  because  there  were 
given  some  more  special  indications  for  the  use  of  this 
important  drug.  Coppez  had  only  first-class  results, 
never  a  failure,  and  never  an  accident.  Menacho  and 
Vallez  unite  in  praising  the  jequirity.  Nicati  saw  some 
good  results  only  when  the  cornea  was  covered  with 
pannus,  and  never  in  the  beginning  of  the  disease.  Some 
men,  like  Galozowski  and  Dor,  never  saw  a  good  result, 
but  Nachet  cured  ten  out  of  eleven  cases.  Armaignac 
had,  in  the  same  patient,  on  one  eye  a  first-class  result, 
on  the  other  eye  a  failure.  He  produced  with  the  mas- 
sage just  as  intense  an  inflammation  as  with  the  jequirity. 
Panas  likes  the  jequirity,  but  only  in  some  inveterate 
cases  with  pannus.  De  Wecker  thinks  it  has  to  be 
avoided  in  aJl  the  cases  where  there  is  the  least  tendency 
to  purulent  discharge.  Gayet  and  Bordet  had  thirty- 
three  failures  with  children.  They  treated  with  jequirity 
some  children  two  years  of  age,  who  had  had,  in  their 
opinion,  for  two  weeks,  granulated  eyelids.  When  you 
read  Bordef  s  paper,  you  do  not  wonder  that  he  obtained 
no  result,  you  only  wonder  that  he  always  continued  to 
treat  other  children,  after  having  had  some  failures  with 
them,  and  that  from  an  experience  limited  to  children  he 
drew  conclusions  about  the  general  use  of  jequirity. 

Some  important  indications  for  the  use  of  jequirity 
were  given  by  Von  Hippel  He  found,  as  Sattler,  that 
the  condition  of  the  conjunctiva  is  of  great  importance. 
When  it  was  covered  with  scars,  then  he  never  obtained 
a  typical  inflammation ;  the  cases  with  papillar  hyper- 
trophy were  also  unfavorable.  Besides,  the  condition 
of  the  cornea  is  of  interest.  A  cornea  which  is  still  in 
good  condition  is  in  greater  danger  from  jequirity  than 
a  cornea  covered  with  pannus,  or  even  an  ulcerated 
cornea. 

In  cases  of  fresh  granulations  with  much  hypersemia 
of  the  conjunctiva,  Von  Hippel  never  saw  a  disappear* 
ance  of  the  granulations.  But  when  the  conjunctiva 
was  pale  and  to  a  large  extent  covered  by  some  hard, 
yellowish,  prominent  granulations,  then  he  had  some 
first-class  results ;  if  there  was  at  the  same  time  pannus, 
the  jequirity  had  a  good  effect  upon  it,  but  it  disappeared 
only  after  two  to  four  months.  .  Some  first-class  results 
were  obtained  in  cases  of  expired  trachoma,  with  atrophy 
and  shrinking  of  the  conjunctiva  and  a  thick  pannus. 

After  all  these  many  observations  it  seems  a  l|Kle 
strange  that  Professor  Jacobson,  of  Kcenigsberg,  Prussia, 
last  summer,  scared  by  one  case  of  panophthalmitis  he 
produced  with  jequirity,  wrote  a  furious  article  against 
De  Wecker  and  the  jequirity  humbug,  as  he  expresses 
himself.  He  admonishes  the  other  physicians  to  be 
cautious,  '^  as  his  case  did  not  seem  to  be  the  only  one 
of  this  kind.''  Also  his  assistant.  Dr.  Vossius,  had  no 
good  results  with  jequirity.  He  used  it  over  fifty  time?, 
but  he  cured  neither  the  acute  hyperaemic  nor  the  pale 
dry  granulations.  He  got  a  good  result  only  at  times  in 
cases  of  old  trachoma  with  scanty  granulations  and 
pannus  ;  still,  in  these  cases  he  likes  better  the  sulphate 
of  copper.  Besides,  he  had  many  accidents ;  three  times 
an  acute  dacryocystitis,  one  time  gangrene  of  the  eyelids, 
fever,  delirium,  a  long-lasting  affection  of  the  ear,  and 
periostitis  of  the  nasal  bones.  Once  the  opacity  of  the 
cornea  grew  worse  and  glaucoma  was  contracted  ;  again, 
he  had  a  purulent  keratitis  and  panophthalmitis.  No 
other  author  had  such  bad  luck  as  Dr.  Vossius.  Dr. 
Chauzeix,  of  Paris,  had  better  success ;  he  used  the 
jequirity  also   in  fifty  cases,  and  with  good  result.     On 


562 


THE  MEDICAL  RECORD. 


[November  22,  1884, 


the  other  side,  Dr.  Schenkl,  of  Vienna,  had  thirty  failures 
with  jequirity. 

1,  for  myself,  am  very  well  satisfied  with  the  jequirity 
after  an  experience  of  over  fifty  eyes  treated  with  it.  But 
I  selected  my  cases  carefully. 

First. — I  never  used  the  jequirity  in  a  child's  eye; 
my  youngest  patient  was  a  girl  of  fifteen  years,  with 
granulations  and  pannus  of  two  years'  standing.  She 
went  three  times  through  the  jequirity  treatment  and  was 
improved  a  great  deal,  but  not  fully  cured.  When  1  dis- 
missed her  she  had  still  a  few  granulations  at  the  fornix 
and  a  slight  pannus.  The  conjunctiva  looked  white,  the 
cornea  a  little  cloudy,  without  veins  ;  but  when  I  kept 
the  eyelids  open  for  a  while,  then  the  conjunctiva  soon 
became  red  and  covered  with  veins,  and  also  on  the 
cornea  appeared  a  few  red  lines  which  disappeared,  to- 
gether with  the  injection  of  the  conjunctiva,  within  a  few 
hours. 

Second, — 1  never  tried  the  cure  in  a  fresh  case  of  gran- 
ulations with  hyperaemia. 

Third. — I  never  proposed  it  in  a  case  of  dry,  yellow- 
ish, sago-like  granulations,  where  the  only  trouble  of  the 
patient  is  sometimes  a  burning  sensation  with  some  weak- 
ness of  the  sight.  1  treated  only  two  eyes  of  this  kind, 
by  the  special  request  of  the  patient,  with  jequirity,  but 
the  granulations  looked,  after  the  treatment,  exactly  as 
before.  1  added  a  few  weeks  of  daily  use  of  bluestone, 
and  succeeded  in  relieving  the  complaints  of  the  patient, 
but  the  granulations  still  exist. 

Such  eyes  are  in  another  danger  from  the  integrity  of 
the  cornea.  I  never  had  a  bad  accident,  but  the  only 
trouble  I  had  was  in  a  case  of  five-year-old  granulations 
with  intact  cornea  ;  the  patient,  a  girl  of  twenty  years, 
had  only  on  one  side  a  little  pannus  at  the  upper  border 
of  the  cornea.  1  was  badly  surprised,  at  the  fourth  day 
of  the  treatment,  when  the  inflammation  was  going  down, 
to  discover  in  the  centre  of  both  corneas  a  gray  infiltra- 
tion, which  lasted  about  two  weeks  and  left  some  slight 
opacities. 

Fourth, — I  would  never  dare  to  treat  with  jequirity  a 
granulated  eyelid  during  one  of  the  inflammations  which 
occur  so  often  in  this  disease.  The  accumulation  of  the 
two  inflammations  might  be  fatal  to  the  cornea. 

The  most  favorable  cases  for  the  jequirity  treatment 
are  those  of  three  years'  or  more  standing,  where  the 
granulations  have  passed  the  acme  of  their  development 
If  the  eyelid  is  equally  thickened  and  the  granulations 
are  no  more  very  prominent,  but  are  imbedded  in  the 
substance  of  the  eyelid,  and  look  more  like  spots  than 
like  buttons,  and  if  the  upper  half  of  the  cornea  is 
covered  with  a  narrow  reticulum  of  fresh  veins,  which  ap- 
peared when  the  patient  "  had  caught  cold  "  and  existed 
for  a  few  weeks  without  any  change,  then  you  have  the 
most  favorable  case  for  the  jequirity  treatment.  Two 
weeks  after  the  first  instillation  of  jequirity  the  pannus 
and  granulations  are  gone,  the  inside  of  the  eyelid  is 
smooth  and  equal  and  has  quite  a  peculiar  appearance, 
yellowish,  pale,  and  gelatinous,  as  if  transformed  into  a 
substance  like  one  of  the  granulations.  As  soon  as  you 
see  this  appearance  you  can  take  the  patient  for  cured. 
The  thickening  of  the  eyelids  never  goes  away. 

Less  favorable  are  those  cases  where  you  find  the  eye- 
lids not  thickened,  but  hardened  and  crooked,  excavated 
at  the  inside  by  curvature  of  the  cartilage,  and  covered 
with  scars  and  some  scanty  prominent  granulations,  and 
where  the  cornea  is  covered  with  a  thin  membrane,  con- 
sisting of  pretty  well  developed  connective  tissue  and  a 
wide-meshed  network  of  old  veins. 

While  I  cured  every  case  of  the  former  kind  with  one 
jequirity  inflammation,  I  had  in  my  cases  of  this  latter  kind 
always  to  repeat  it,  and  to  add  for  so  long  a  while  treat- 
ment with  atropia  and  yellow  ointment  that  I  did  not 
know  to  which  I  owed  the  final  result.  In  these  cases 
the  corneal  trouble  has  by-and-by  grown  independent  of 
the  granulations ;  it  is  (if  there  do  not  exist  any  irritating 
eyelashes)  maintained  by  the  irregular  form  and  the  scars 


of  the  upper  lid,  and  the  chief  remedy  is  the  atropia 
Bluestone,  which  gives  so  good  results  in  cases  without 
corneal  trouble,  is  quite  useless  in  such  cases ;  yellow 
ointment  does  good  if  combined  with  atropia.  1  did  not 
see  any  harm  done  by  the  jequirity ;  even  the  whole 
process  of  the  cure  seemed  to  be  shortened  by  it,  but  it 
is  too  hard  to  judge  about  that,  as  the  duration  of  the 
trouble  is  also  very  different  when  treated  alone  with 
atropia  and  yellow  ointment. 

When  the  cornea  has  been  affected  for  a  long  while  in 
a  more  serious  way  the  corneal  trouble  continues  after 
the  granulations  are  gone,  sometimes  in  the  most  favor- 
able cases.  One  patient  of  mine,  whom  I  treated  eighteen 
months  ago  with  jequirity  with  a  good  result,  calls  about 
every  six  months  at  my  office  with  a  fresh  pannus  ;  it  ap- 
pears quite  suddenly  in  a  night  and  disappears,  after  in- 
stillation  of  atropia,  within  a  few  days.  When  he  came 
to  me  he  had  granulations  of  ten  years'  standing,  the  eye- 
lids were  thickened  and  covered  at  the  inside  with  granu- 
lations. The  cornea  was  covered  with  pannus  and 
several  ulcers  and  spots.  The  eyes  had  been  sore  the 
last  four  months  without  interval,  and  he  was  nearly 
blind.  The  granulations  disappeared  within  two  days 
after  a  treatment  of  five  applications  of  a  two  per  cent, 
infusion.  The  ulcers  of  the  cornea  healed  up  within  four 
weeks,  and  left  only  some  slight  spots  and  an  irregular 
astigmatism.  The  lids  remained  thickened,  their  inside 
became  smooth  and  took  the  appearance  as  above  de- 
scribed. For  the  watering  of  the  eye  I  split  the  tear- 
points  and  introduced  the  probes  a  few  times,  as  I 
always  do  after  the  jequirity  treatment.  After  treatment 
in  this  way  he  was  enabled  to  do  his  work  as  a  stonemason, 
and  till  to-day  there  has  been  no  change  in  his  eyes  ex- 
cept the  above-mentioned  slight  attacks. 

Another  trouble  which  outlasts  sometimes  the  granu- 
lations are  relapses  of  iritis.  If  anybody  with  granulated 
eyelids  contracts  an  iritis  with  synechias  in  connection 
with  his  corneal  trouble,  then,  of  course,  this  is  not  cured 
by  the  jequirity;  still  the  strong  diminution  of  the  intra- 
ocular pressure,  which  cannot  be  produced  by  any  drug 
in  such  a  degree  as  by  the  jequirity,  may  have  a  good  in- 
fluence upon  it. 

As  for  the  danger  from  the  jequirity,  I  am  not  afraid 
of  that.  If  we  take  the  great  number  of  cases  treated 
with  jequirity  till  now,  in  comparison  with  the  few  eyes 
destroyed  by  it,  then  we  cannot  say  that  it  is  a'danger- 
ous  thing.  Besides,  we  must  take  m  consideration  that 
a  good  many  of  the  accidents  happened  in  the  beginning, 
when  we  were  not  yet  acquainted  with  the  indications 
for  the  use  of  the  new  drug.  Manfredi  allows  himself 
that  he  used  too  strong  solutions,  others  may  have  had 
some  unsuitable  cases  which  they  would  now  no  more 
treat  with  jequirity.  It  is  hard  for  me  to  judge  about 
that,  because  I  could  not  find  out  the  details  of  all  those 
cases ;  but,  for  instance,  Jacobson's  case  was  absolutely 
unsuitable  for  the  jequirity  treatment.  His  case  was  a 
middle-aged  woman',  with  evidently  expired  granulations. 
She  had  the  last  attack  of  inflammation  fifteen  years  ago. 
Jacobson  used  the  jequirity  with  the  intention  to  clear 
up  an  opacity  of  the  cornea  which  existed  since  the 
childhood  of  the  patient,  and  was  nearly  free  of  veins. 
The  inside  of  the  eyelids  were  covered  with  scars,  Ja- 
cobson does  not  say  that  he  saw  any  granulations;  be- 
sides, she  had  a  blepharophimosis  and  a  partial  symble- 
pharon  posterius.  Indeed  he  diminished,  eight  days 
before  the  beginning  of  the  cure,  the  phimosis  by  cutting 
the  external  corner,  but  it  is  nevertheless  more  than  proba- 
ble that  in  this  case  the  cornea  was  exposed  to  quite  an 
extraordinary  pressure.  I  do  not  think  that  from  Jacob- 
son's  case  any  other  conclusion  can  be  made  but  that 
the  jequirity  was  used  in  a  case  unfitted  for  it. 

The  presumption  that  all  the  cases  ending  fatally,  in 
which  no  too  strong  solutions  were  used,  have  been  in  a 
similar  way  unfitted  for  the  jequirity  treatment,  like  the 
one  of  Jacobson,  is  the  only  explanation  I  can  give  for 
their  loss.     If  the  jequirity  would  be  a  dangerous  rem- 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


563 


edy,  as  the  gonorrhoeic  virus  seems  to  be  for  the  eye, 
then  I  think  I  should  also  have  had  an  accident  in  my 
fifty  cases.  I  used  in  no  case  less  than  three  applica- 
tions of  a  two  per  cent,  infusion  within  nine  hours,  the 
first  one  at  9  a.m.,  the  second  one  after  noon,  and  the 
third  one  at  6  p.m.  Often  I  added  even  a  few  more  on 
the  second  day,  when  the  eye  was  already  inflamed. 

But  I  allow  that  the  necessity  of  selecting  the  cases 
properly  is  a  great  impediment  to  the  general  use  of  the 
jequirity  by  the  physicians.  This  is  shown  by  the  experi- 
ence of  Professor  Jacobson,  who  selected  his  unfitted  case 
for  a  trial  with  the  jequirity  just  because  he  mistook  it 
for  a  very  suitable  one.  I  should  be  happy  if  my  lines 
would  help  a  little  in  this  regard,  and  I  am  fully  con- 
vinced that  the  jequirity,  if  confined  to  the  proper  cases, 
will  by  and  by  get  proper  recognition  as  a  beneficial 
remedy. 

THE    TREATMENT    OF    DYSPEPSIA    BY    HOT 
WATER. 

By  THOMAS  W.   SHEARDOWN,  M.D., 

WINONA^   MINN. 

In  reference  to  the  paper  entitled  "The  Therapeutic 
Eflfects  of  the  Internal  Administration  of  Hot  Water  in  the 
Treatment  of  Nervous  Diseases,"  as  read  by  Dr.  Ranney 
at  the  meeting  of  the  New  York  Academy  of  Medicine, 
October  i6th,  and  published  in  The  Record  of  October 
25th,  my  own  personal  experience  may  afford  some  items 
of  interest 

Let  me  premise  by  stating  that  I  have,  until  one  year 
ago  this  last  September,  always  enjoyed  the  most  robust 
health,  have  been  something  of  an  athlete,  having  required 
medicinal  treatment  but  once  in  my  life,  and  that  for  pneu- 
monia when  twelve  or  fourteen  years  old,  from  which  I 
fully  recovered  in  due  time.     During  the  last  week  in 
August,  1883,  I  came  near  being  prostrated  firom  sun- 
stroke ;  did  not  lose  consciousness,  however,  but  came 
within  an  ace  of  it.     The  week  following  I  commenced 
having  some  trouble  with  my  digestion,  vomiting  occasion- 
ally, this  emesis  soon  becoming  more  and  more  frequent 
until  I  voniited  a  portion  of  every  meal  taken.     Now,  by 
vomiting  I  do  not  mean  just  simply  spitting  up  a  mouth- 
ful, or  a  small  portion  of  food  now  and  then,  but  a  square 
old-fashioned  vomit,  ejecting  a  major  portion  of  the  con- 
tents of  the  stomach  each  time.     This  act  of  emesis  was 
preceded  by  no  pain  or  nausea  whatsoever,  absolutely 
none,  nor  have  I  ever  experienced  any  pain  or  nausea 
either  bcforey  during^  or  after  the  act  of  vomiting,  simply 
an  uncomfortable  feeling  which  would  not  subside  until 
the  food  was  ejected ;  then  instandy  all  was  serene  and 
quiet  until  after  the  next  meal.     I  could  vomit  easily, 
with  no   trouble  at  all,  and  at  any  hour  of  the  day  or 
night.     The  usual  time  for  ejecting  my  food  (for  it  be- 
came a  habit)  was  from  one-half  to  two  and  a  half  hours 
after  eating.     There  seemed  not  to  be  so  much  trouble 
with   my    powers  of  digestion   as   with  absorption   and 
assimilation,  for  the  act  of  chymification  seemed  to  be 
performed  all  right     The  stomach  seemed  to  prepare 
the  food,  but  there  it  would  lie  in  a  pulpy  mass,  the  sys- 
tem refusmg  to  take  it  up,  except,  of  course,'in  very  limited 
quantities.      I  was  not  always  actually  compelled  to  vomit 
after  each  meal,  for  I  could,  by  exercising  all  of  my  will 
power,  keep  it  and  carry  it  over  a  meal,  or  even  two 
meals,  but   there  it  would  lie,  and  until  I  emptied  my 
stomach  I  was  always  uncomfortable — mind,  no  pain,  or 
nausea,  or  heartburn,  or  anything  of  the  kind ;  simply  an 
uncomfortable  feeling  that  was  instantly  relieved  by  empty- 
ing the  stomach. 

This  condition  of  afiEsdrs  went  on  for  about  three  months, 
viz.,  from  the  first  week  in  September,  1883,  until  the  day 
after  Thanksgiving.  During  this  time  I  had  tried  all,  or 
nearly  all,  the  modes  of  treatment  and  remedies  recom- 
mended by  our  best  authors.  All  of  the  pepsines,  pan- 
creatines,  lactopeptines,  saccharalid  and  otherwise,  acids 
and  alkalies,   strychnia,  nux  vomica,  and  arsenic,  etc.. 


ad  infinitum ;  in  fact,  all  of  the  recognized  forms  of  treat- 
ment— of  course  endeavoring  to  govern,  regulate,  and  re- 
strict my  diet.  From  the  pepsines,  lactopeptines,  and  pep- 
tones, I  derived  positively  not  the  slightest  benefit  nor 
from  the  acid  treatment.  From  alkalies  followed  by  arsenic 
I  received  some  temporary  benefit,  but  soon  relapsed  into 
the  same  old  rut  of  constant  and  regular  emesis.  I  was 
constipated,  of  course,  and  was  obliged  to  resort  con- 
stantly to  laxatives,  and  used  the  common  "  seidlitz 
powder  "  more  than  anything  else.  Aside  from  this,  my 
general  health  was  pretty  good.  I  had  a  ravenous  ap- 
petite all  the  time,  invariably  arising  from  the  table 
hungry ;  had  no  headache,  no  pulmonary  or  catarrhal 
difficulty ;  urine  normal  in  color  and  quantity,  but  a 
little  deficient  in  weight.  Occasionally  would  see  the 
black  specks  of  indigestion  before  my  eyes,  and  at 
five  or  six  different  times  my  eyes  would  lose  the  power 
of  accommodation  for  a  short  time  only.  In  trying  to 
read  or  write,  my  words  would  all  run  together  and  be 
blurred,  and  I  could  not  make  my  pen  follow  the  line, 
and  for  a  few  minutes  I  could  not  exercise  the  power  of 
speech  with  control ;  I  could  not  say  what  I  wanted  to. 
I  would  try  to  say  a  certain  word  or  phrase,  ask  or  an- 
swer a  certain  question,  and  I  would  say  something  else 
entirely  irrelevant.  I  would  know  and  realize  instantly 
when  I  used  the  wrong  words,  and  would  stop  and  try 
again,  and  after  several  times  trying  and  using  all  my 
will  power  in  concentration  of  my  mind  and  thoughts  I 
could  get  my  words  right.  These  nervous  irregularities 
only  occurred  a  few  times  and  only  for  a  few  minutes, 
not  over  ten  or  fifteen,  at  a  time ;  but  tliey  were 
accompanied  by  a  little,  not  much,  dizziness,  a  very 
weak  and  faint  feeling  pervading  the  whole  system — 
an  indescribable  sick  feeling  not  to  be  localized,  but 
general.  These  nervous  phenomena  and  sickness  would 
pass  away  immediately  after  lying  down  flat  on  my  back. 
I  think  I  have  outlined  the  details  of  the  trouble 
from  which  I  suffered.  Let  me  repeat  one  thing  to 
make  the  point  I  am  coming  to  more  striking.  From  the 
first  week  in  September  until  the  day  after  Thanksgiving 
— about  three  months — I  vomited  every  single  day,  never 
less  than  twice  (unless  I  would  force  myself  to  retain  nay 
food),  and  frequently  four  and  five  times.  I  am  safe  in 
saying  I  vomited  not  less  than  three  hundred  and 
fifty  times  in  that  length  of  time.  I  had  lost  fifty  pounds 
in  weight,  and  was  becoming  very  nervous,  irritable,  de- 
spondent, and  disheartened.  Was  losing  all  energy  and 
becoming  very  weak.  How  I  got  enough  nourishment 
to  sustain  life  at  all  is  still  a  mystery  to  me.  I  had  been 
carefully  dieting  myself,  and  regulating  and  restricting 
food  both  in  quantity  and  kind,  with  no  benefit  whatever, 
and  on  Thanksgiving  Day  I  made  up  my  mind  I  would 
eat  at  least  one  more  square  meal,  let  come  what  would, 
so  I  ate  a  hearty,  old-fashioned  turkey  dinner,  with  its  ac- 
companiment of  mince  pie,  English  pudding,  etc.,  top- 
ping off  with  a  plentiful  supply  of  egg-nogg.  As  a 
natural  consequence,  I  was  very  sick,  more  so  than 
ever  before.  Just  the  day  previous  I  had  read  Dr. 
Cutler's  article,  in  the  London  Lancet^  on  the  use  of  hot 
water  in  dyspepsia,  and  without  much  faith  made  up  my 
mind  to  try  it.  The  last  thing  at  night  on  Thanksgiving 
was  to  empty  my  stomach  again,  and  the  first  thing 
the  next  morning  I  had  my  maid  bring  a  pint  of  hot 
water,  boiling  hot,  to  the  bed  before  I  got  up.  I  took  a 
clean  rubber  catheter  and  sucked  the  hot  water  through 
that,  it  being  so  hot  I  could  not  touch  my  lips  to  it  at  all, 
nor  hold  the  vessel  in  my  bare  hands.  I  drank  all  of 
the  water  in  less  than  twelve  minutes.  I  laid  in  bed  an 
hour  and  a  half,  and  then  got  up  and  ate  my  breakfast  of 
porterhouse,  baked  potatoes,  bread  and  butter,  and  coffee, 
and  I  kept  it  down,  and  with  no  unpleasant  feelings.  At 
10.30  A.M.  I  drank  twenty  ounces  of  hot  water  taken  from 
the  fire  boiling,  and  taken  through  a  tube  as  before,  ate 
dinner  at  12  o'clock  and  retained  it.  At  4.30  p.m.  I  drank 
twenty-four  ounces  of  hot  water,  and  at  6  o'clock  ate  my 
regular  supper  and  retained  it.     I  drank  sixteen  ounces 


564 


THE   MEDICAL  RECORD. 


[November  22, 1884, 


more  half  an  hour  before  retiring.  The  next  day  I 
went  through  the  same  performance  again,  taking  sixteen 
ounces  each  lime,  and  likewise  every  day  until  Christ- 
mas Day.  Not  once  did  I  miss  taking  my  lyater  in  six- 
teen-ounce  doses,  nor  did  I  vary  five  minutes  from  my 
regular  time ;  nor  did  I  during  that  time  take  one 
drop  of  liquid  food,  milk,  tea,  coffee,  or  cold  water,  or 
any  hot  water,  except  at  the  time  specified. 

After  the  first  draught  of  hot  water  not  one  single 
time  did  I  vomit,  until  Christmas  Day,  when  I  foolishly 
omitted  my  hot  water,  and  partook  of  a  Christmas  din- 
ner from  which  1  was  sick  the  remainder  of  the  day  and 
the  day  following ;  but  recourse  to  hot  water  soon  cor- 
rected it.  Now,  this  shows  the  efficacy  of  the  hot-water 
treatment.  It  stopped  the  vomiting  at  once — not  slowly 
or  gradually,  but  at  once.  From  Christmas  until  the 
middle  of  last  September,  about  nine  months,  I  used  the 
hot  water,  but  not  as  regularly  as  I  should  have  done.  I 
would  use  it  a  couple  of  weeks  at  a  time,  and  it  would 
stop  the  vomiting  at  once,  but  after  ceasing  I  would  oc- 
casionally eject  my  food,  but  only  after  some  indiscre- 
tion in  diet.  I  removed  from  Tennessee  (Knoxville, 
where  I  had  lived  the  last  year)  to  my  old  home  in  Min- 
nesota, and  since  I  have  reached  here,  my  native 
State,  and  where  I  have  lived  nearly  my  entire  life,  I 
have  been  able  to  discontinue  the  hot  water  entirely,  and 
remain  well,  gaining  strength  every  day  and  fast  recover- 
ing my  normal  weight.  This  change  of  climate  has,  of 
course,  helped  to  benefit  me.  Then  one  great  auxiliary 
to  the  hot-water  treatment  I  have  found  out  is  an  almost 
exclusively  meat  diet^  putting  as  little  of  a  fermenting 
nature  into  the  stomach  as  possible.  It  has  been  said 
of  this  hot- water  treatment  that  it  is  very  slow  in  its  ef- 
fects. In  my  own  case  it  acted  at  once,  from  the  very 
first  draught. 

The  modus  operandi  of  the  hot  water  in  my  own  case, 
I  must  confess,  I  do  not  fully  understand.  I  had  always 
considered  my  trouble  reflex  in  character,  and  due  to 
some  irritation  to  the  pneumo-gastric  from  overheat.  For 
the  past  ten  months  I  have  used  hot  water  in  my  prac- 
tice in  quite  a  number  of  cases  of  dyspepsia,  indigestion, 
and  allied  gastric  troubles,  and  with  most  excellent  re- 
sults every  time  when  the  treatment  was  persevered  in 
for  any  length  of  time.  Ordinarily,  I  think,  the  hot 
water  acts  more  mechanically  than  otherwise,  by  moder- 
ately distending  the  walls  of  the  stomach  and  washing 
them  thoroughly,  carrying  down  all  debris,  thus  leaving 
the  stomach  perfectly  sweet  and  clean  for  the  reception 
of  food.  The  presence  of  the  water  hot  would  tend  to 
allay  the  inflamed  mucous  surfaces,  and  also  tend  to 
stimulate  the  secretion  of  the  gastric  juices,  cold  water 
having  a  diametrically  opposite  tendency  in  my  humble 
estimation.  The  ingestion  of  cold  water,  and,  in  fact, 
any  and  all  fluids,  must  be  absolutely  prohibited ;  no  coffee^ 
no  milky  no  tea. 

After  drinking  the  hot  water  in  the  prescribed  quan- 
tities regularly  for  two  or  three  days,  there  will  be  no 
sense  of  thirst  between  meals,  as  it  were,  the  draught  of 
hot  water  effectually  satisfying  all  the  demands  of  the 
system  for  liquids.  The  patient  will  begin  to  even  relish 
the  large  dose,  which  at  first  thought  seems  so  unpalata- 
ble. 1  used  the  hot  water  all  in  all  for  nearly  a  year, 
and  never  got  tired  of  the  taste.  There  is  only  one  ob- 
jection to  its  use,  and  that  is  the  amount  of  time  con- 
sumed and  the  bother  and  trouble  in  its  preparation. 
After  continued  use,  should  it  pall  on  the  taste,  flavor 
with  a  few  dops  of  essence  of  peppermint  or  cinnamon, 
or  a  few  drops  of  any  of  the  dilute  mineral  acids  make  a 
pleasant  change. 

The  rules  laid  down  by  Dr.  Cutler,  also  by  Dr.  Ran- 
ney,  must  be  rigidly  enforced.  I  can  fully  endorse  them. 
Without  following  closely  these  directions  you  cannot 
make  a  success  of  the  "  hot-water  cure."  Let  me  formu- 
late them  again,  i.  Prohibit  absolutely  all  other  liquids. 
2.  Drink  the  water  in  as  large  quantities  as  will  effectually 
satisfy  all  demands  of  thirst,  as  hot  as  can  be  borne,  four 


times  daily,  an  hour  and  a  half  before  each  meal  and  half 
an  hour  before  retiring,  the  object  being  to  have  the 
stomach  as  nearly  empty  as  possible  when  the  water  is 
taken,  and  to  give  it  time  to  get  out  of  the  stomach  be- 
fore food  is  taken,  thus  avoiding  dilution  of  the  food.  3. 
Limit  your  patients  to  as  near  an  exclusive  meat  (rare) 
diet  as  possible. 

These  three  rules,  if  rigidly  enforced  and  followed  out, 
I  fully  believe,  will  effectually  control  that  bugbear  of 
American  physicians — dyspepsia. 

November  x«  1884. 


DEAD    TEETH    IN    THE     JAWS. 
By  R,  wood  brown,  D.D.S.,  M.D., 

LATE  DENTISl-  TO  THE  OUT-OOOK  SBKMCB  OF  THE  LONG  ISLAND  COUJtGF 
HOSPITAL. 

Under  the  above  title  there  have  appeared  in  Thk 
Record  several  articles  the  reading  of  which  has 
prompted  me  to  pen  this  paper.  I  shall  notice  the  dif- 
ferent points  irrespective  of  Uie  order  in  which  they  ap- 
pear, limiting  myself  more  particularly  to  the  editonal  of 
October  4,  1884. 

The  statement  in  the  fore  part  of  second  section  of  the 
editorial  of  above  date  says :  "  It  would  not  be  strange  if, 
in  the  course  of  events,"  "when  all  teeth  without  pulps, 
and  hence  in  process  of  more  or  less  decay,  as  well  as 
those  which  the  deposit  of  tartar,  or  other  cause,  had 
entirely  divested  of  periosteal  nourishment,  would  be 
promptly  condemned  as  unfit  to  remain  in  the  jaws." 
We  take  the  liberty  of  disagreeing  with  the  editor  as 
regards  the  ffrst  part  of  this  statement,  and  we  think  he 
is  wrong  in  the  latter  part. 

Teeth  without  pulps  are  not  necessarily  dead.  Dr.  J. 
Morgan  Howe,  Medical  Record,  October  18,  1884, 
writes  correctly  that  teeth  "  are  not  in  an  appreciable 
degree  deprived  of  periosteal  nourishment  by  the  death 
of  the  pulp."  When  we  have  a  periosteum  destroyed  wc 
almost  always  find  a  pulpless  tooth,  but  we  do  not  con- 
sider a  tooth  or  root  dead  unless  the  entire  periosteum 
is  absorbed ;  a  tooth  may  be  a  living  structure  long  after 
the  pulp  is  dead  or  removed.  If  we  should  extract  a 
tooth  in  a  normal  condition,  crack  it  open,  and  try  to  re- 
move the  pulp  from  its  bed  with  a  pair  of  pliers,  we  wiD 
notice  that  there  is  some  difficulty  in  so  doing.  Why  ? 
Because  the  pulp  is  attached  to  its  parietes  by  odonto- 
blasts, which  are  connected  to  the  pulp  by  small  bands, 
and  to  the  dentine  bv  fibrillae  which  enter  the  dental 
tubes.  It  is  thus  shown  why  the  dentine  is  so  sensitive 
when  attacked  by  caries,  also  the  part  it  takes  in  the 
nourishment  of  the  member.  Now,  take  the  same  tooth 
and  make  a  section  of  the  root,  and  we  will  find,  under 
the  microscope,  that  the  dentine  is  composed  of  tubes 
one-ten-thousandth  of  an  inch  in  diameter ;  that  the 
crusta  petrosa,  or  cementum,  is  made  up  of  lacunae  and 
canaliculi,  but  no  Haversian  canals ;  also  that  the  perios 
teum  is  full  of  blood-vessels.  We  will  also  see  that  the 
tubes  are  connected  to  the  lacunae  and  canaliculi  directly 
and  by  interglobular  spaces,  and  that  the  latter  are  in 
connection  with  the  periosteum. 

Again,  if  we  view  a  transverse  section  of  dentine,  we 
will  notice  that  the  tubes  contain  fibrillae  or  a  substance 
capable  of  carrying  nourishment.  In  a  dry  section,  the 
contents  being  contracted,  this  substance  can  be  seen 
more  easily.  We  have  now  a  direct  connection  between 
the  dentine  and  periosteum,  and  can  understand  why  the 
pulp  is  not  necessary  to  the  vitality  of  the  tooth,  having, 
as  it  does,  ability  to  draw  nourishment  from  the  perios- 
teum, thereby  maintaining  its  normal  condition.  It 
should  be  remembered  that  membrane  covering  the  pulp 
is  continued  through  the  apical  foramen  and  becomes  the 
periosteum  upon  the  roots.  If  there  is  a  membrane  lin- 
ing the  pulp  chamber,  we  have  not  been  able  to  find  it. 
What  part  the  pulp  takes  as  regards  tooth  structure,  after 
the  tooih  is  formed,  is,  we  think,  not  positively  known,  but 
our  experience  tells  us  that  teeth  are  just  as  liable  to  de- 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


565 


cay  with  pulps  as  without  them.     The  damage  from  caries 
is  done  before  the  dentine  is  reached ;  the  cause  of  caries 
is  from  without,  not  from  within.     If  a  tooth  is  perfect 
when  erupted,  it  will  last  a  lifetime  unless  injured  by 
acids  or  abrasion.     Pulps  counteract  decay  so  far  as  to 
throw  out  lime  salts  into  the  dental  tubuli,  which  make  a 
more  perfect  barrier  to  the  encroachments  of  decay  ;  this 
same  process  goes  on  after  a  nerve  is  capped.     The  den- 
tice  after  this  change  is  called  osteo-dentine  ;  why,  we  do 
know,  as  our  microscopical  investigations  have  not  shown 
any  characteristics  of  bone  in  the  so-called  osteo-dentine. 
This  action  of  the  pulp  in  resisting  decay  is  the  only 
part  it  takes  in  nourishing  the  tooth,  and  even  here  there 
is  not  sufficient  pabulum  thrown  out  to  resist  the  encroach- 
ment, much  less  to  restore  broken  down  structure.     The 
only  result  from  the  barrier  thrown  out  by  the  irritated 
pulp  is  a  retardation  of  the  progress  of  decay.     The  very 
fact  that  a  large  number  of  pulpless  teeth  and  roots  are 
retained  in  the  mouth  without  periostitis,  ulitis,  or  suppu- 
ration, is  sufficient  testimony  that  dental  pulps  are  not  at 
all  necessary  to  the  retention  of  teeth  ;  also  that  pulpless 
teeth  should  not  ''be  condemned  as  unfit  to  remain  in  the 
jaws,"  and  that  teeth  are  not  necessarily  in  the  process 
of  more  or  less  decay  *'  because  deprived  of  nourishment 
on  account  of  dead  or  extirpated  pulps. 

As  to  the  latter  part  of  the  editorial  statement — "  as 
well  as  those  which  the  deposit  of  tartar,  or  other  cause, 
had  entirely  divested  of  periosteal  nourishment,  would  be 
promptly  condemned  as  unfit  to  remain  in  the  jaws." 
The  main  point  here  is  the  divestment  of  the  perios- 
teum. We  do  not  think  a  root  ought  to  be  removed  for 
the  reason  that  there  is  no  periosteum ;  it  does  not  follow 
that  the  root  is  offensive  and  discharging  purulent 
matter  because  divested  of  its  membrane.  There  are  two 
kinds  of  decay,  hard  and  soft,  the  latter  emitting  a  dis- 
agreeable odor,  the  former  not  doing  so.  Memory  bears 
us  out  in  saying  that  crowns  of  teeth  are  more  apt  to  be 
the  prey  of  .soft  decay  than  are  the  roots.  The  excep- 
tions in  these  cases  prove  the  rule.  If  a  root  is  entirely 
divested  of  periosteum,  the  crown  gone  and  no  diseased 
tissue  surrounding  it,  there  should  be  some  hesitation 
before  condemning  and  removing  from  the  jaws.  Every 
root  taken  from  either  maxillas  weakens  the  arch  and 
seriously  threatens  its  usefulness.  Again,  the  presence 
of  tartar  or  salivary  calculi  does  not  always  threaten  the 
life  or  usefulness  of  a  tooth,  even  if  the  entire  periosteum 
under  the  deposit  is  destroyed.  We  have  seen  teeth 
covered  with  tartar  to  such  an  extent  as  to  preclude  the 
probability  of  any  membrane  remaining,  yet  for  years 
after  they  have  been  doing  good  service. 

There  are  certain  conditions  which  should  govern  the 
extraction  of  teeth  or  roots,  and  they  are  pre-eminently 
pathological.  Periostitis,  where  it  is  not  traumatic,  indi- 
cates one  of  two  causes,  or  may  both — a  diseased  pulp  or 
periosteum.  Here  it  is  bad  practice  to  extract,  if  of 
recent  origin  ;  if  chronic  and  the  roots  crownless,  we 
advise  imuiediate  removal.  If  there  is  a  probability  of 
the  disease  abating  and  there  is  enough  structure  to  work 
upon,  then  extraction  should  be  a  dernier  ressort  Af- 
fected teeth  with  crowns  are  more  liable  to  produce  in- 
flammation and  its  train  of  disturbances  than  are  roots 
alone,  owing  to  continued  irritation  by  mastication. 

Periostitis  does  not  always  destroy  the  periosteum,  but, 
if  mild  and  chronic,  may  produce  a  condition  known  as 
exostosis.  This  many  times  is  the  cause  of  neuralgia 
from  pressure  upon  the  nerve.  Many  patients  are  dosed 
with  all  the  neurotics  known,  without  the  thought  of 
chronic  inflammation  of  the  dental  organs ;  yet,  on  the 
other  hand,  many  a  dental  arch  is  sacrihced  without  caus- 
ing relief.  Teeth  in  which  the  pulp  remains  after  death 
very  often  causes  discoloration  from  hematine  which  is 
absorbed  into  the  dental  tubuli. 

The  editorial  remarks  in  the  latter  part  of  the  second 
section,  relative  to  the  danger  from  putrescent  teeth,  are 
not  too  strong,  but  to  the  point,  and  certainly  they  do 
not  merit  discussion  ;  in  fact,  they  are  irrefragable. 


The  object  of  this  paper  is  an  endeavor  upon  the  part 
of  the  writer  to  correct  what  he  thinks  is  an  erroneous 
idea — the  idea  that  teeth,  because  diseased,  should  be  con- 
demned as  unfit  for  the  jaws ;  also  to  show  why  they 
should  be  allowed  to  continue  their  usefulness.  It  should 
not  be  forgotten  that  roots  preserve  the  contour  of  the 
dental  arch,  and  are  not  always  foreign  bodies  when  the 
pulp  is  destroyed,  even  if  both  pulp  and  periosteum  have 
ceased  to  perform  their  functions.  We  know  that  many 
constitutional  disturbances  are  attributable  to  diseased 
dental  organs,  and,  owing  to  professional  inability,  many 
teeth  are  lost.  This  naturally  leads  us  to  the  third  sec- 
tion of  the  editorial  mentioned,  which  speaks  of  dental 
education.  It  is  lamentably  true  that  a  large  number  of 
dentists  are  utterly  incapable  of  treating  severe,  compli- 
cated cases  of  diseased  teeth,  but  we  must  not  enter  the 
field  of  dental  education,  although  it  is  a  subject  which 
has  occupied  our  mind  and  pen,  and  is  still  occupying 
our  thoughts. 

ElXVBNTII  AND  MaIN   StRKBT,    KanSAS  CiTY,   Mo. 


BUCCAL   BREATHING. 

Its  Causes,  Serious  Consequences,  Prevention,  and 
Cure.* 

By  GEORGE   W.   MAJOR,   B.A.,  M.D., 

LATE  CLINICAL  ASSISTANT  IN  THK  HOSPITAL  FtJR  UlSBASES  OK  THE  THROAT  AMD 
CHEST,  LONDON,  ENC. :  INSTRUCTOR  IN  LARVNGOIjOGV  AND  DISEASES  OP  THE 
THROAT,  M*GILL  UNI\'SRSITV,  .MONTREAL,  CAN.,'  FELLOW  OK  THE  AMERICAN 
LAXYNGOLUGICAL  ASSOCIATION  .'  I'HYSICIAN  TO  THE  MONTREAL  GENERAL  OUT- 
PATIENT DEPARTMENT. 

The  habit  of  breathing  through  the  mouth,  instead  of 
through  the  nose,  is  so  very  prevalent,  and  its  serious 
results  so  little  appreciated,  that  I  have  been  induced  to 
make  it  the  subject  of  a  few  remarks  before  this  Associa- 
tion. The  first  breath  of  life  is  taken  through  the  nostrils, 
and  if  this  precedent  should  not  prove  sufficient  to  satisfy 
us  of  the  natural  mode  of  respiration,  let  us  refer  to 
Genesis,  where  we  learn  that  at  the  creation  of  man 
"  He  breathed  into  his  nostrils  the  breath  of  life."  The 
instinct  of  the  savage  mother  leads  her  to  carefully  close 
the  lips  of  her  sleeping  infant,  lest  the  cold  air  might 
prove  injurious  should  it  enter  the  lungs  by  the  passage 
of  the  mouth. 

The  professional  trainer  insists  upon  the  athlete  breath- 
ing with  closed  mouth.  The  fireman  entering  a  burning 
building  carefully  avoids  speaking,  or  the  parting  of  his 
lips.  It  is  recorded  that  one  may  breathe  mephitic  air 
for  a  short  time  through  the  nose,  if  the  lips  are  firmly 
sealed.  The  army  surgeon  requires  the  raw  recruit  to 
undergo,  in  his  examination,  physical  fatigue  with  closed 
lips. 

All  these  decisions  have  been  arrived  at  as  the  result 
of  observation,  though  no  doubt  to  many  of  those  who 
insist  that  under  certain  circumstances  nasal  respiration 
should  be  strictly  observed,  the  true  reason  for  this  pre- 
caution may  be  quite  obscure,  or  perhaps  entirely  un- 
known. Nine  out  of  every  ten  persons  will  tell  you  that 
the  nose  is  the  organ  of  the  sense  of  smell,  quite  oblivious 
of  the  more  important  function  of  respiration. 

This  question  of  oral  respiration  is  one  that  has  not 
even  at  this  late  day  received  at  the  hands  of  the  pro- 
fession the  study  and  research  it  truly  merits.  If  it  is  the 
result  of  mechanical  obstruction  of  a  permanent  nisiture,  it 
is  not  a  habit  but  zn  unfortunate  necessity ;  but,  on  the 
other  hand,  temporary  nasal  swellings  often  develop  a 
habit  which  is  unconsciously  and  innocently  pursued 
with  the  most  serious  results  to  health  and  development. 
Any  one  of  a  number  of  conditions  may  singly  give  rise 
to  oral  respiration,  but  we  generally  find  more  than  one 
present  before  man  allows  himself  to  be  converted  into 
a  mouth-breather. 

In  the  human  economy  the  nose  performs  several  ini- 

^  Read  before  the  Canada  Medical  Asbociatioiii  held  at  Montreali  August  26, 
1884. 


566 


THE  MEDICAL   RECORD. 


[November  22,  1884. 


portant  functions,  the  chief  being  that  of  a  respirator.  It 
purines,  moderates  the  temperature  and  moistens  the 
air  before  it  reaches  the  sensitive  larynx  and  lungs.  It 
purifies  the  air  by  arresting  foreign  and  irritating  particles 
in  their  passage  through  the  cavities  of  the  nose.  It 
moderates  the  temperature  of  the  air  by  rendering  it  as 
nearly  that  of  the  human  body  as  possible.  It  moistens 
the  air  by  virtue  of  the  secreting  power  of  its  lining 
membrane  and  glands. 

An  example  of  its  first  influence  may  be  had  in  the  fact 
that  in  oral  respiration  dust  will  lodge  in  the  pharynx  and 
larynx  that  under  otherwise  normal  conditions  would 
scarcely,  if  at  all,  gain  an  entrance  to  these  organs.  Of 
the  second,  on  going  into  the  cold  outer  air  of  winter  a 
single  breath  through  the  mouth  will,  by  its  impact,  pro- 
voke cough  and  a  sensation  of  coldness,  which,  if  taken 
through  the  nostrils,  would  be  so  moderated  that  on  reach- 
ing the  lower  border  of  the  palate  it  would  give  to  one's 
sensation  no  appreciable  difference  of  temperature,  and 
could  be  breathed  with  comfort  and  impunity.  Of  the 
third,  if  from  any  cause  nasal  respiration  is  impeded,  say 
during  the  night,  we  rise  with  dry,  harsh  palate,  tongue, 
and  throat,  the  secretion  of  the  buccal  mucus  being  neither 
so  constituted  nor  sufficient  to  moisten  the  air  and  keep 
the  parts  themselves  in  a  healthy  state. 

The  mouth  was  alone  intended  for  the  taking  of  food 
and  speech;  it  is,  therefore,  not  very  remarkable  that 
many  and  baneful  results  should  follow  in  the  wake  of 
those  who  violate  the  natural  laws  by  putting  parts  to 
uses  for  which  nature  never  intended  them. 

Certain  physical  deformities  result  from  this  habit,  ag- 
gravated in  the  same  proportion  as  that  in  which  this 
hurtful  method  is  practised.  Among  these  may  be  men- 
tioned general  debility ;  malnutrition,  as  shown  in  spare 
habit  of  body  and  undersize;  deformed  chest,  with 
prominent  sternum,  sunken  sides,  retraction  at  the  line 
of  attachment  of  the  diaphragm,  and  rounded  shoulders. 
The  upper  lip  is  more  or  less  shortened,  the  mouth 
open  to  a  greater  or  less  degree,  the  upper  central  inci- 
sors generally  prominent,  with  irregular  development  of 
the  symphysis  of  the  upper  jaw.  The  alae  of  the  nose 
are  thin  and  flattened,  and  the  muscles  of  the  nose  and 
its  neighborhood  wasted.  These  conditions  are  always 
more  marked  on  the  side  of  greatest  obstruction.  The 
face  presents  a  pinched  expression.  We  also  find  an  ex- 
pression of  stupidity  in  aggravated  cases,  with  loss  of 
memory  occasionally — these  two  latter  possibly  the  re- 
sult more  of  intemasal  pressure  than  of  mouth-breathing 
directly. 

Dupuytren  many  years  ago  associated  pigeon-breast 
with  large  tonsils;  but  in  point  of  fact  any  interfer- 
ence with  nasal  respiration,  be  the  cause  what  it  may, 
will,  if  of  sufficient  gravity,  produce  this  deformity.  In 
addition  to  the  appearance  laid  down  as  indications  of 
oral  respiration,  I  have  observed  an  abnormal  acute- 
ness  in  the  development  of  the  upper  jaw,  whereby  the 
hard  palate  is  of  great  vertical  depth,  with  corresponding 
narrowing  from  side  to  side.  The  central  incisors  in 
this  class  of  cases  are  not  prominent,  but  usually  show  at 
the  middle  line  near  the  margin  of  the  gums  a  point  of 
decay. 

It  is  also  worthy  of  passing  comment  to  note  the 
frequency  with  which  we  encounter  decay  of  the  upper 
teeth.  According  to  my  idea  this  is  largely  dependent 
upon  mouth-breathing.  I  do  not  think  the  prevalent 
opinion,  that  the  cause  lies  in  the  escape  of  corroding 
gases  from  the  stomach,  is  altogether  a  correct  one.  An 
offensive  breath,  in  my  experience,  arising  from  the  stom- 
ach, is  somewhat  infrequent.  The  odor,  if  not  of  de- 
cayed teeth,  is  most  probably  that  of  decomposed  nasal 
or  pharyngeal  secretions,  the  tendency  to  change  being 
manifest  in  disordered  constitutional  conditions,  especially 
if  accompanied  by  any  elevation  of  temperature.  The 
injury  to  the  upper  teeth  may  be  regarded  as  the  result 
of  dryness  caused  by  the  passage  of  air  between  and 
around  them,  facilitating  decomposition  of  any  food  pres- 


ent, and  favoring  the  fonnation  of  acids  capable  of  reacting 
vigorously.  The  lower  teeth  are  protected  by  the  lip 
and  tongue,  and  moistened  by  the  saliva,  and  are  there- 
fore free  from  the  evil  influences  exerted  above. 

The  injury  to  digestion,  as  a  direct  result  of  impairment 
of  the  power  of  mastication,  at  once  suggests  itself.  It  is 
not  during  the  day  only  that  the  subject  of  oral  respira- 
tion suffers ;  at  night  the  aggravation  is  intensified.  The 
position  of  the  body  during  sleep  favoring,  as  it  does,  . 
increased  flow  of  blood  to  the  head,  the  result  is  in- 
creased  difficulty,  as  shown  by  the  open  mouth,  snoring, 
and  general  restlessness,  the  latter  the  direct  resuh  of 
deficient  oxygenation,  assisted  no  doubt  by  the  fact  that 
during  sleep  the  voluntary  respiratory  muscles  used  dur- 
ing  the  day  are  no  longer  available. 

I  trust  I  shall  not  be  considered  as  taking  an  extreme 
view  if  I  should  state  that  after  a  careful  inquiry  I  have 
found  that  in  a  large  proportion  of  mouth-breathers  in- 
voluntary  micturition  during  the  night  is  not  unusual 
This  latter,  of  course,  is  attributable  to  carbonic-acid-gas 
poisoning — the  sensitive  air-passage  refusing  to  take  in 
the  cold,  dry,  impure  air,  and  as  a  result,  there  is  deficient 
lung  expansion  and  aeration.  It  is  unnecessary  here  to 
enlarge  upon  the  consequences  of  deficient  oxygenation, 
they  are  patent  to  every  one. 

The  principal  causes  that  lead  to  mouth-breathing  are 
the  various  deviations  of  the  nasal  septum ;  ecchondrosis 
and  exostosis  of  the  nasal  fossae  ;  hypertrophy  of  the  tur- 
binated bones  or  of  their  soft  tissues ;  dilatation  of  the 
various  sinuses,  whether  of  a  permanent  or  temporary 
character ;  tumors  of  various  kinds,  known  as  polypi ; 
oedema  of  the  septum,  particularly  common  at  its  pos- 
terior border ;  overgrowth  of  the  erectile  tissue  of  the 
posterior  temiinaiions  of  the  lower  turbinated  bones; 
adenomata  ot  the  vault  of  the  pharynx,  being  an  hyper- 
trophy  of  Luschka's  tonsil ;  growths  in  the  same  region, 
the  most  common  being  fibroids  and  hypertrophy  of  the 
buccal  tonsils. 

As  the  habit  of  mouth-breathing  is  developed  usually 
in  early  childhood,  its  prevention  must  largely  depend 
upon  the  recognition  by  those  in  charge  of  the  forma- 
tion of  an  unnatural  and  hurtful  method  of  respiration. 
In  order  to  do  this,  mothers  and  nurses  must  first  know 
that  the  nose  is  the  proper  channel  by  which  air  enters 
and  leaves  the  lungs. 

If  the  practice  is  merely  the  result  of  habit,  induced 
by  some  temporary  nasal  or  naso-pharyngeal  obstruction, 
the  simple  closure  of  the  mouth  after  clearing  the  nostrils 
will  generally  suffice  ;  or  if  still  more  obstinately  pursued, 
a  bandage  tied  under  the  chin  and  over  the  head  will 
serve  to  keep  the  jaws  in  contact.  If  there  be,  however, 
any  mechanical  impediment,  as  swelling,  hypertrophy,  or 
growths,  they  must  be  treated  radically.  The  age  of  the 
child  never  should  negative  surgical  procedure,  as  the 
conseqences  resulting  from  neglect  of  early  interference 
may  be  fraught  with  very  serious  af^er-injury.  In  early 
infancy  I  have  more  than  once  used  the  galvano-cauteiy 
with  the  most  satisfactory  results. 

It  is  manifestly  the  duty  of  the  profession  to  teach  the 
public  that  the  nose  is  the  organ  of  respiration ;  that 
it  is  also  the  organ  of  smell  they  will  themselves  discover. 
It  now  remains  to  briefly  refer  to  the  treatment  essential 
for  the  removal  of  the  obstacle  to  free  nasal  respira- 
tion. The  first  cause  referred  to,  and  perhaps  the  most 
common,  is  deviation  of  the  nasal  septum.  I  may  say 
that  in  practice  it  is  almost  the  exception  to  see  a  straight 
one.  Deviation  of  the  septum  may  be  single,  double,  or 
multiple,  and  this  may  take  place  in  a  vertical,  horizontal, 
or  diagonal  line,  or  present  so  many  irregularities  as  to 
occupy  every  possible  direction. 

In  many  cases,  especially  of  vertical  deviation,  the 
angle  at  which  the  cartilaginous  septum  is  bent  is  so 
acute  that  the  nostril  in  which  the  convexity  presents  it- 
self is  often  so  perfectly  close  as  to  be  utterly  useless  for 
any  purpose  of  respiration  :  the  prospective  gain  on  the 
opposite  side  is  neutralized  either  by  an  hypertrophy  of 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


567 


the  lower  or  middle  turbinated  bone  and  soft  tissue,  or 
perhaps  by  a  second  deviation  posteriorly,  giving  the  sep- 
tum a  sigmoid  shape.   As  regards  the  side  to  which  the 
deviation  exists  most  frequently,  statistics  of  over  seventy 
cases  compiled  by  myself  do  not  show  any  very  special 
selection  as  to  right  or  left,  but  to  the  left,  if  anything. 
No  doubt  exists  in  my  mind  that  deviations  are  the  re- 
sult of  mechanical  violence — blows  or  falls  on  the  nose. 
Females,  though  presenting  deviation,  do  so,  for  obvious 
reasons,  very  much  less  frequently  than  males,  and  also 
show  a  much  less  exaggerated  type.    In  prize-fighters,  or 
those  who  have  engaged  much  in  boxing,  the  cartilagi- 
nous septum  is  bent  into  every  possible  shape,  without 
very  severely  affecting  nasal  respiration  or  the  external 
form  of  the  nose.     In  these  cases  the  cartilage  is  tele- 
scoped downward  much  on  the  principle  of  a  mast,  but 
without   radically  closing   the   side   passages.      It   has 
seemed  to  me  that  a  vertical  deviation  is  more  likely  to 
date  from  an  injury  received  in  childhood  than  from  one 
later  in  life,  and  an  analysis  of  cases  strengthens  this  belief. 
In  May  last  I  saw  a  lady,  Miss  T ,  aged  thirty- 
seven,  who  had  been  confined  to  her  bed  for  five  months, 
suffering  from  the  most  excruciating  form  of  headache, 
which  had  refused  to  yield  to  a  variety  of  treatment.    On 
examination  nasal  obstruction  from  swelling  of  the  mu- 
cous lining  was  found,  deviation  of  the  septum  posteriorly, 
and  more  or  less   tiue   hypertrophy  of  the   turbinated 
bones.     Means,  such  as  nasal  inhalations  and  sprays,  af- 
forded some  relief  by  reduction   of  the  swelling  of  the 
membrane,  and  much  more  decided,  if  not  absolute  immu- 
nity from  pain  was  had  by  successive  applications  of  the 
galvano-cautery.     This  result  was  obtained  purely  as  the 
result  of  diminished  pressure.     At  first  the  patient  was 
incapable  of  even  standing  alone,  but  in  a  few  short 
weeks  had  gained  strength,  and  is  now  perfectly  restored 
to  health. 

A  second  instance.  Miss  M ,  aged  twenty-eight,  who 

had  for  some  months  been  the  subject  of  hallucinations, 
and,  at  times,  of  violent  mania,  was  referred  to  me  for  a 
pain  felt  on  the  right  side  of  the  head  behind  the  ear, 
and  covering  a  space  of  the  area  of  the  palm  of  one's 
hand.  Nasal  obstruction  in  the  right  nostril,  the  result 
of  deviation,  was  noted,  and  when  in  the  course  of  three 
weeks  it  was  somewhat  reduced  the  mental  condition  had 
wonderfully  improved,  and  convalescence  is  now  com- 
plete. The  pain,  which  was  described  as  a  sense  of 
pressure,  impTOvtd ^ari passu  with  the  reduction  of  the 
nasal  stenosis  —  as  in  like  proportion  did  the  mental 
state.  Each  must  draw  his  own  inference  from  the  re- 
port of  this  case. 

Under  the  head  of  deviation,  a  rather  interesting  ab- 
normal hyper-development  of  the  vomer,  giving  rise  to 

buccal  breathing,  might  find  place.     Miss  D ,  aged 

twenty-two,  was  sent  to  me  for  treatment  by  my  es- 
teemed friend.  Dr.  Arthur  A.  Browne,  of  this  city.  Na- 
sal breathing  was  impossible,  and  more  or  less  deafness 
was  also  complained  of.  The  anterior  nares  showed  no 
cause.  On  exploring  the  vault  with  the  index  finger  a 
very  peculiar  state  of  affairs  was  found  to  exist.  It  gave 
the  impression  to  the  touch  of  a  partition  running  an- 
tero-posteriorly,  dividing  the  naso-pharynx  into  two  sep- 
arate lateral  chambers.  This  bony  extension  refused  to 
be  displaced,  and  seemed  continuous  with  the  vomer  in 
fioat,  being  joined  to  the  vault  above,  and  to  the  poste- 
rior superior  pharyngeal  wall  behind.  On  examination 
with  the  rhinoscopic  mirror  the  above  description  was 
verified.  It  was  covered  with  mucous  membrane,  which 
had  undergone  catarrhal  swelling,  obstructing  the  passage 
of  air  and  pressing  on  the  Eustachian  orifice  laterally. 
Under  appropriate  treatment  the  engorgement  was  re- 
lieved, and  with  it  all  the  discomforts  for  which  advice 
was  originally  sought.  There  is  but  one  other  case  of 
the  kind  on  record,  that  reported  by  Dr.  John  N.  Mac- 
kenzie, of  Baltimore. 

The  fourth  and  last  case  that  I  shall  present  to  you  is 
that  of  a  prominent  canon  who  applied  more  for  relief 


from  vocal  disability  than  for  any  pain  or  nasal  incon- 
venience, fie  was  a  confirmed  mouth-breather,  proba- 
bly from  childhood.  There  was  an  extreme  vertical  de- 
viation of  the  cartilaginous  septum  to  the  left,  entirely 
obstructing  the  nasal  passage  of  that  side,  while  the  con- 
cavity on  the  right  was  occupied  by  a  long  myxomatous 
tumor.  The  soft  palate  clung  listlessly  to  the  pharynx, 
having  long  since  forgotten  its  function.  The  removal 
of  the  growth,  which  was  of  considerable  size,  afforded 
some  relief,  and  as  hypertrophies  were  reduced  by  local 
medication  and  the  galvano-cautery,  satisfactory  prog- 
ress was  made.  Though  no  attempt  has  been  made  as 
yet  to  operate  on  the  deviation  directly,  manipulation  of 
it  twice  or  thrice  daily  by  the  subject  himself,  shows 
considerable  alteration  of  its  outlines.  Meantime  the 
palate  has  gained  some  tonicity,  and  breathing  is  carried 
on  by  the  nose  almost  entirely.  Snoring  at  night  also 
has  ceased,  and  the  voice,  some  months  ago,  was  suffi- 
ciently recovered  to  fill  a  large  church  at  a  crowded 
service.  These  disabilities,  however  trifling  they  may 
appear  to  the  casual  observer,  may  be,  as  in  this  gentle- 
man's case,  sometimes  a  serious  obstacle  to  preferment. 
The  health  also  suffers  from  the  exertion  necessary  to 
make  one's  self  heard  from  the  pulpit ;  the  naso-pha- 
ryngeal  cavities  ceasing  to  be  resonators,  much  greater 
pressure  is  necessary  to  produce  voice. 

These  cases  have  been  briefly  referred  to  for  the  pur- 
pose of  showing  how  various  and  serious  may  be  the 
consequences  of  internasal  pressure,  and  how  speedily 
and  easily  measures  aimed  in  the  proper  direction  may 
give  assurance  of  relief  and  cure. 

For  the  relief  of  deflection  or  deviation  of  the  nasal 
septum  a  variety  of  means  have  been  from  time  to  time 
suggested,  but  it  is  practically  only  in  cases  of  the  vertical 
form  that  operative  interference  is  either  urgently  called 
for  or  hkely  to  be  of  value.  The  method  (Ingalls', 
of  Chicago)  that  most  commends  itself,  both  from 
its  simplicity,  as  also  its  successful  results,  is  that  in 
which  the  mucous  membrane  of  the  deviated  side  and 
the  cartilage  are  carefully  divided  in  a  triangular  man- 
ner, the  apex  being  upward,  the  cartilage  dissected  from 
the  mucous  membrane  of  the  opposite  side  and  removed, 
the  septum  being  brought  into  line  with  pliers,  and  the 
divided  mucous  membrane  held  by  sutures  and  a  pad  of 
some  soft  antiseptic  material.  The  resiliency  of  the  car- 
tilage is  such  that  a  portion  must  be  removed  equal  to 
the  redundancy,  in  order  to  acquire  a  straight  line.  Of 
the  many  punches  introduced  but  one  seems  to  me  to 
fulfil  all  the  requirements,  and  at  the  same  time  to  be 
comparatively  free  from  fault.  It  is  one  (Sajous',  of 
Philadelphia)  in  which  a  blade  can  be  fixed  at  any  de- 
sired angle,  and  the  septum  divided  through  from  side  to 
side,  and  straightened  by  allowing  overlapping,  or  the 
excess  may  be  removed  and  the  cut  edges  placed  in  line 
and  held  by  plugs  until  healed. 

All  the  operations  whereby  openings  between  the  nos- 
trils were  caused  are  unwarrantable,  as  forming  a  space 
for  the  accumulation  of  dried  secretions.  It  is  not  un- 
usual to  find  nature  performing  the  operation  of  removal 
of  the  deviation  by  setting  up  ulceration  and  necrosis  of  a 
portion  of  cartilage  of  the  size  of  a  sixpence,  or  even 
larger.  When  this  occurs  pressure  only  is  relieved,  and 
no  appreciable  gain  is  secured  the  nose  as  an  air-passage. 
Ecchondrosis  and  exostosis  are  of  not  uncommon  oc- 
currence, and  are  capable  of  removal  by  scalpel,  saw,  or 
pliers,  but  more  nicely  by  means  of  the  surgical  engine 
and  burr ;  no  violence  is  used,  pain  is  trifling,  and  the 
time  occupied  in  performance  is  very  brief. 

Hypertrophy  of  the  turbinated  bones,  if  very  consid- 
erable, is  also  best  reduced  by  the  drill  attachment,  af- 
terward crushing  down  and  washing  out  the  debris.  The 
hemorrhage  is  slight  compared  with  that  resulting  from 
the  use  of  gouges  and  other  means  of  destruction.  Hy- 
pertrophy of  the  soft  tissues,  with  or  without  dilatation  of 
the  venous  sinuses,  whether  partial,  general,  temporary, 
or  permanent,  has  for  many  years  been  looked  upon 


568 


THE  MEDICAL  RECORD. 


[November  22,  1884. 


therapeutically  as  a  most  unsatisfactory  complaint.  When 
chronic,  it  has  generally  been  termed  hypertrophic  ca- 
tarrh, and  when  acute,  hay-fever,  summer  catarrh,  coryza, 
and  so  forth.  The  various  methods  adopted  for  the 
treatment  of  either  the  chronic  or  acute  variety  have ' 
been  eminently  unsatisfactory,  more  especially  was  this 
the  case  in  the  latter. 

In  the  chronic  variety  caustics  were  employed,  whereby 
large  areas  of  tissue  were  destroyed,  and  great  and  pro- 
longed pain  ensued,  or  the  actual  cautery  was  introduced 
through  the  nostrils  and  applied  so  as  to  form  deep 
sloughs,  depending  upon  the  cicatricial  contractions  for 
a  cure.  In  the  acute  form  the  use  of  various  lotions  and 
pigments  served  the  purpose  of  cleansing  the  tissue,  with 
little  or  no  effect  in  shortening  the  duration  or  prevent- 
ing a  recurrence  of  the  attack. 

Independently  of  the  pain  and  risks  attending  the  em- 
ployment of  caustics  in  the  nose,  the  function  of  the 
organ  must  be  somewhat  interfered  with  if  much  of  its 
lining  membrane  is  destroyed,  and  on  the  latter  ground 
alone  recourse  to  these  means  is  somewhat  questionable. 
The  actual  cautery  as  well  as  the  thermo-cautery  pre- 
sent the  not  unimportant  drawbacks  that  they  must  be 
heated  before  being  introduced,  and  unless  both  patient 
and  practitioner  are  uncommonly  steady,  and  the  passage 
less  tortuous  than  usual,  more  parts  will  be  brought  in 
contact  with  the  heated  instrument  than  desired. 

In  the  galvano-cautery,  on  the  contrary,  we  possess  an 
appliance  that  answers  all  possible  requirements.  It  is 
under  perfect  control ;  it  does  not  destroy  needlessly  ;  it 
is  not  heated  until  in  contact ;  it  is  comparatively  pain- 
less, and  if  employed  with  ordinary  care  it  need  be  fol- 
lowed by  no  evil  consequence. 

The  method  of  employing  it  in  the  chronic  variety  is 
somewhat  thus :  After  introducing  the  knife  as  far  back 
as  possible,  to  turn  on  the  current,  drawing  the  electrode 
slowly  forward,  steadily  pressing  its  cutting  edge  against  the 
hypertrophy,  thus  scoring  the  tissue.  This  may  be  done 
several  times  at  each  sitting.  The  good  effects  that  fol- 
low  are  not  only  the  result  of  the  contraction  of  the 
mucous  membrane,  binding  down,  as  it  were,  the  enlarged 
venous  sinuses,  but  also  the  dividing  of  a  number  of  mi- 
nute superficial  vessels  bloodlessly  at  each  passage  of 
the  knife,  while  at  the  same  time  but  little  sacrifice 
of  tissue  is  engendered. 

In  the  acute  variety  the  procedure  is  somewhat  different, 
and  for  this  reason :  in  those  so-called  cases  of  hay-asthma, 
or  hay-fever,  there  exists  an  unnatural ,  excitability  or  hy- 
persensitiveness  of  the  nasal  mucous  membrane,  and  it 
is  necessary  to  first  allay  that  before  scoring.  This  is 
best  accomplished  by  passing  the  flat  of  the  knife  as  freely 
as  possible  over  all  the  lining  membrane  within  easy 
reach,  and  thus  proceeding  to  incise  deeply  in  a  linear 
manner  as  before  described.  That  summer  catarrh  has 
no  peculiar  relation  to  either  the  pollen  of  hay  or  of  the 
rose,  or  to  any  other  spore  or  animal  exhalation,  is  now 
pretty  well  acknowledged.  If  any  additional  proof  be 
needed  to  strengthen  this  view,  it  may  be  found  in  the 
fact  that  all  manner  of  treatment  based  upon  the  spore 
theory,  heretofore  introduced,  has  ignominiously  failed, 
and  the  treatment  by  galvano-cautery  has  been  as  uni- 
formly successful. 

The  beneficial  effect  of  high  elevations  in  this  sadly 
misunderstood  complaint  is  not  that  it  frees  the  mem- 
brane from  contact  with  irritating  substances,  but  may 
safely  be  attributed  to  the  influence  a  rare  atmosphere 
has  in  unloading  the  local  apoplexy,  thus  rendering  the 
membrane  less  irritable.  I  have  had  under  observation 
a  case  where  a  lady,  the  subject  of  hay-fever,  thrived 
amid  four  hundred  acres  of  timothy,  and  on  returning  to 
the  city  was  forthwith  attacked  by  her  old  enemy. 

Of  the  various  tumors  likely  to  be  met  with  in  the 
naso-pharynx  as  obstructions  to  nasal  respiration,  there 
maybe  mentioned  the  gelatinous,  polypous,  and  the  fibroid 
— the  former  very  common,  the  latter  rather  rare.  The 
usual  method  of  removal  of  the  myxomatous  variety  by 


forceps  is  somewhat  objected  to  popularly,  especially  if 
it  has  been  once  undergone.  The  forceps  oftentimes  is 
the  best  means,  however,  of  reaching  the  growths,  ex- 
cepting perhaps  the  various  snares,  properly  curved  and 
armed  with  a  special  wire.  These  snares  can  be  intro- 
duced painlessly,  and  the  growth  engaged  in  the  loop, 
gradually  working  up  its  pedicle  and  running  it  close 
to  its  attachment.  An  application  of  the  galvano-cau- 
tery now  will  prevent  any  likelihood  of  return.  The 
fibroid  tumor,  though  capable  of  removal  by  the  forceps, 
can  be  best  cut  through  at  its  origin  by  the  galvano- 
cautery  wire  ecraseur,  and  whatever  pedicle  remains 
may  be  effectually  destroyed  by  an  application  of  the 
electrode.  A  simple  metho4  in  the  myxomatous  variety 
is  to  pass  the  knife  through  and  sear  up  the  body  of  Ae 
tumor,  thus  exposing  the  pedicle  to  view,  and  leisurely 
proceeding  to  cut  it  from  its  attachment  with  the  same 
instrument.  This  method  has  also  the  advantage  of 
being  painless. 

One  peculiar  feature  I  have  observed  is  the  difficulty, 
and,  I  may  say,  the  danger,  attending  the  use  of  anaes- 
thetics in  subjects  of  nasal  or  naso-pharyngeal  tumors, 
when  nasal  breathing  is  impossible  or  very  difficult. 

M.  A.  C came  under  notice  December,  1882,  com- 
plaining of  suflfocative  attacks  on  retiring  for  the  night 
On  examination  of  larynx,  congestion  was  found; 
pharynx  also  involved  in  the  hyperaemia.  A  posterior 
rhinoscopic  examination  was  impossible,  owing  to  spas- 
modic action  of  velum  and  attacks  of  difficult  breathing. 
Anteriorly,  nares  were  found  congested ;  anterior  illumi- 
nation showed  at  posterior  orifices  a  white,  glistening 
surface,  visible  through  both  nasal  passages.  A  probe 
passed  was  opposed  by  a  partially  yielding  body, 
preventing  the  further  passage  into  the  vault.  This  dtf- 
ficulty  was  reinforced  by  recurring  spasm  of  the  soft 
palate  packing  up  the  space.  Tumor  was  diagnosed. 
All  efforts  with  forceps  used  posteriorly  were  rendered 
futile  by  the  spasmodic  action  of  the  velum  and  choking 
on  the  part  of  the  patient.  Snares  were  borne  heroically, 
but  all  attempts,  even  with  the  finger  passed  behind, 
were  unavailing  in  engaging  the  growth,  though  fre- 
quently repeated.  Education  of  the  pharynx  was  equally 
unsuccessful.  On  June  7,  1883,  assisted  by  my  friend 
Dr.  Roddick,  chloroform  was  administered,  and  so  badly 
borne  that  inversion  and  drawing  out  of  the  tongue, 
which  had  been  swollen,  were  practised,  the  jaws  requir- 
ing first  to  be  forced  open.  Some  minutes  later,  by 
passing  my  finger  up  behind  the  palate  and  directing  the 
palmar  surface  backward,  I  succeeded  in  forcing  the 
tumor  against  the  pharyngeal  wall,  and  by  steady  press- 
ure downward  tore  it  from  its  attachment.  Bleeding 
was  very  free.  The  growth  proved  to  be  a  fibroid, 
and  was  on  its  anterior  surface  bilobular,  intimately 
adapting  itself  to  the  nasal  orifice,  while  posteriorly  it 
was  spherical,  giving  a  cast  of  the  vault. 

The  galvanic  cautery  was  applied  under  chloroform 
(which  was  now  well  borne)  to  the  base  of  the  tumor. 

An  examination  a  year  afterward  developed  no  re- 
currence. The  principal  difficulty  was  referred  to  the 
left  subclavicular  region,  and  flattening  was  undoubtedly 
present,  but  no  sign  of  dulness  or  other  organic  change 
was  observed. 

A  second  case,  W.  M ,  male,  aged  seventeen,  was  re- 
ferred to  me  at  the  Throat  Clinic  of  the  Montreal  General 
Hospital,  by  Dr.  Roddick.  In  this  case  the  right  nostril 
was  the  seat  of  attachment.  The  tumors  showed  from 
the  anterior  nares,  and  the  auriscope  and  finger  develo]»td 
the  fact  of  extension  into  the  pharyngeal  space.  They 
were  found  to  be  attached  to  the  middle  turbinate.  Two 
were  removed  by  forceps  anteriorly,  and  the  third  and 
largest  one  was  pried  backward  as  described  in  the 
former  instance.  Bleeding  was  free,  but  easily  arrested. 
These  growths  gave  rise  to  difficult  breathing  and  asth- 
matic attacks,  with  occasional  bronchitis,  for  over  two 
years.  The  cautery  was  used  a  week  later  to  the  field 
of  attachment. 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


569 


CEdema  of  the  septum,  diagnosed  by  rhinoscopy,  is 
easily  overcome  by  either  passing  a  long  needle,  made 
for  the  purpose,  through  all  tissue  necessary  for  remov- 
al, and  afterward  passing  the  cold  wire  down  over  and 
cutting  through ;  but  still  more  simply  and  expeditiously 
with  the  galvano-cautery  knife,  one  or  two  sittings  ac- 
complishing the  task  painlessly  and  effectually.  Over- 
growth of  the  erectile  tissue  of  the  lower  turbinated  bone 
sometimes  causes  an  obstruction  to  breathing,  acting 
Almost  after  the  fashion  of  a  valve  at  the  posterior  ori- 
fice of  the  nasal  passage.  I  have  removed  a  pair  as 
large  as  small  plums,  that  were  the  provoking  cause  of 
one  of  the  most  severe  attacks  of  asthma  I  have  ever 
seen.  For  the  removal  of  these  bodies  the  cold  wire 
straight  6craseur  is  best  and  most  satisfactory,  although 
using  the  curved  electrode  from  behind  the  velum  has 
answered  well  when  from  deviation  of  the  septum  or 
other  causes  a  snare  could  not  be  passed  by  the  anterior 
nares. 

Adenomata  of  the  vault  may  greatly  obstruct  nasal 
breathing,  and  need  instrumental  interference.  In  early 
childhood,  when  they  are  soft  and  numerous,  they  can 
generally  be  easily  scraped  off  with  the  finger-nail.  In 
the  adult  they  become  more  tough,  when  forceps,  snares, 
or  the  hooded  galvano-cauter}',  become  necessary.  These 
growths  are  very  common,  and  are  very  frequently  asso- 
ciated with  hypertrophy  of  the  buccal  tonsil.  They  may 
be  looked  upon  as  the  result  of  anterior  nasal  disorders, 
and  secondary  to  them.  The  tonsil  of  Luschka  tends  to 
atrophy  at  adult  life,  unlike  the  buccal  tonsil,  so  that 
we  may  safely  and  truthfully  say,  in  so  far  as  the  Eusta- 
chian tonsil  is  concerned,  that  the  child  will  outgrow  ity 
a  statement  often — ^unfortunately  too  often  for  the  well- 
being  of  the  child — made  use  of  with  regard  to  the  buccal 
tonsiL  The  buccal  tonsils,  when  hypertrophied,  offer  an 
obstruction  to  nasal  respiration  often  more  by  their  back- 
ward pressure  on  the  posterior  palatine  pillars  than  by 
reason  of  their  bulk.  When  the  enlargement  is  very 
great,  both  oral  and  nasal  breathing  is  impeded ;  this  is 
the  cas  !  especially  in  the  recumbent  position. 

In  1828  Dupuytren  noticed  the  frequency  of  chest  de- 
formity in  cases  of  enlarged  tonsillar  glands.  Chassaig- 
nac,  in  1843,  observed  that  although  increased  efifort 
of  the  diaphragm  neutralizes  to  a  certain  extent  the  im- 
pediment to  respiration  offered  by  enlarged  tonsils,  there 
are  frequent  intervals  when  the  power  of  this  muscle 
becomes  temporarily  exhausted,  and 'the  oxygenation  of 
the  blood  is  very  incompletely  performed. 

Both  these  observers  attributed  the  ill  effects  of  en- 
larged tonsils  to  the  fact  that  they  impeded  the  entrance 
of  air  into  the  lungs,  and  not  to  the  real  cause,  namely, 
the  prevention  of  air  entering  the  lungs  from  the  nasal 
passage  above.  The  pharynx  is  sufficiently  spacious  to 
admit  of  a  volume  of  air  much  greater,  even  if  seriously 
obstructed  by  enlarged  tonsils,  than  could  possibly  pass 
through  the  narrow  anterior  and  posterior  nasal  orifices. 
The  spacious  mid-chambers  of  the  nose  were  intended 
for  the  purpose  of  preparing  atmospheric  air  for  healthy 
lung  respiration,  and  have  no  influence  whatever  on  the 
quafitity  capable  of  being  transmitted  through  the  nasal 
passages.  As  to  the  wisdom  of  the  so-called  extirpation 
of  the  tonsils,  when  they  act  as  mechanical  impediments 
to  respiration,  there  seems  to  me  to  be  no  doubt  The 
various  fears  entertained  concerning  the  influence  of  their 
ablation  on  general  development  are  purely  chimerical. 

I  do  not  think  I  exaggerate  in  saying  that  in  one  hun- 
dred and  forty-two  tonsillotomies  performed  by  myself 
the  patients  or  their  friends  had  reason  to  re^et  the 
results  obtained  by  its  performance.  Surgical  interfer- 
ence is  the  only  means  of  satisfactorily  getting  rid  of 
these  abnormal  growths,  and  it  has  seemed  quite  safe 
in  its  performance.  I  have  had  one  hemorrhage,  not  a 
very  severe  one,  more  the  result  of  the  obstinacy  of  the 
patient  than  of  the  operation.  The  tonsillitome  is  the 
safest,  best,  and  most  expeditious  means  of  operation, 
and  an  instrument  after  Physic's  pattern  is  much  to  be 


preferred.  Rest  in  the  recumbent  position  should  be 
enjoined  for  four  or  more  hours  afterward.  Crushed  ice 
should  be  used  freely,  and  an  astringent  of  tannic  and 
gallic  acid  applied.  Bearing  in  mind  the  possibility  of 
hemorrhage,  and  taking  the  precaution  for  the  preven- 
tion of  it,  will  surely  go  far  to  render  the  liability  to  it, 
however  little,  less. 

It  is  generally  but  not  always  necessary  to  remove  both 
tonsils.  A  curious  fact,  call  it  a  coincidence  if  you  will,  ob- 
served during  the  last  epidemic  of  diphtheria  was,  that  in 
not  less  than  three  subjects  in  whom  it  had  been  necessary 
that  but  one  tonsil  should  be  removed,  no  exudation 
occurred  on  the  surface  of  the  ablatized  tonsil,  and  but 
very  little  in  its  vicinity.  This  was  very  well  marked  in 
one  case,  a  very  severe  one,  which  was  seen  daily  by  Dr. 
Browne  and  myself  for  a  period  of  over  three  weeks. 
The  membrane,  though  uniformly  spread  over  both  sides, 
avoided  entirely  the  cicatrized  surface,  and  yielded  much 
more  readily  in  its  neighborhood.  Possibly  the  relief  of 
the  parts  from  the  irritating  presence  of  the  enlargement 
had  some  influence  in  this  direction. 

In  conclusion,  I  may  be  permitted  to  sa^,  and  it  is  a 
verdict  that  has  not  been  arrived  at  hastily,  that  the  very 
best  means  possible  for  preserving  a  healthy  chest  and 
throat  are  to  be  found  in  nasal  respiration.  In  fact,  a 
being  who  breathes  as  nature  intended  should  not 
suffer  from  any  throat  affection,  or  at  all  events  should 
enjoy  considerable  immunity  therefrom.  Bronchial 
asthma  is  most  common  in  mouth-breathers,  and  mouth- 
breathing  is  as  hereditary  as  asthma.  I  do  not  go  too 
far  when  I  assert  boldly  that  a  healthy  state  of  the  lining 
of  the  pharynx,  larynx,  and  lungs  is  incompatible  with 
any  form  of  respiration  but  the  nasal.  I  have  thus 
briefly  and  incompletely  endeavored  to  draw  your  atten- 
tion to  what  I  am  free  to  consider  one  of  the  prevailing 
disorders  of  the  day.  I  do  not  claim  to  have  announced 
anything  new,  but  rather  to  have  emphasized  our  duty 
to  society  in  regard  to  this  most  important  but  elemen- 
tary point. 

Nephrectomy  for  Calculous  Pyelitis. — Dr.  A. 
Salomoni  {La  Gazetta  degli  Ospitali^  August  31,  1884), 
reports  a  case  in  which  Professor  £.  Bottini,  of  Milan, 
successfully  removed  the  kidney.  The  patient,  aged 
twenty-seven,  had  had  two  calculi  removed  by  lateral 
lithotomy  fifteen  years  previously.  Three  years  after 
that  operation  an  abscess  formed  in  the  right  iliac  fossa. 
It  opened  spontaneously,  and  after  a  few  months  reap- 
peared in  the  lumbar  region,  when  it  was  opened  with 
caustic  potass.  A  permanent  fistuala  resulted,  and 
proved  intractable  to  all  local  and  constitutional  treat- 
ment The  patient  lying  on  the  left  side,  under  chloro- 
form. Professor  Bottini,  under  strict  antiseptic  precau- 
tions, made  a  vertical  incision  through  the  whole  ilio-costal 
space,  three  inches  outside  the  quadratus  luniborum. 
The  kidney  having  been  isolated,  the  renal  artery  was 
secured  m  one  ligature,  the  vein  and  ureter  in  Another. 
The  space  having  been  well  cleared  and  all  bleeding 
stopped,  a  drainage-tube,  about  one-third  of  an  inch  in 
diameter,  was  introduced.  The  walls  of  the  fistula  were 
excised,  and  the  wound  united  by  one  deep  metallic  su- 
ture and  eight  superficial  silk  ones.  The  operation 
lasted  a  little  over  an  hour.  The  antiseptic  dressing  was 
renewed  daily,  the  metallic  suture  was  removed  on  the 
third,  and  the  silk  ones  on  the  fourth  day,  when  the 
drainage-tube  was  shortened.  It  was  withdrawn  on 
the  eighteenth  day.  Progress  was  uninterrupted.  The 
highest  temperature,  99.5°,  was  reached  the  second  day; 
urine  in  normal  quantity  and  without  deposit  was  passed 
without  pain  or  trouble.  The  patient  left  his  bed  on  the 
sixth,  and  went  home  the  eighteenth  day,  when  only  a 
slight  sinus  remained,  about  an  inch  deep.  The  fistula 
led  into  the  pelvis  of  the  kidney,  which  was  dilated, 
with  thickened  and  suppurating  walls,  and  contained,  be- 
side some  uric-acid  sand,  two  small  calculi  about  the 
size  and  shape  of  grains  of  barley. 


570 


THE  MEDICAL  RECORD. 


{November  22, 1884. 


The  Medical  Record: 


A  Weekly  journal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editok. 


PUBUSHSD  BY 

WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 
New  York,  November  22,  1884. 

ON  THE  LIMITATIONS  OF  THE  KNOWLEDGE 
REGARDING  CHOLERA, 

It  is  only  by  constant  reiteration  that  knowledge  is 
finally  inculcated  and  public  opinion  afifected.  In  this 
we  find  a  justification  for  the  firequent  and  discursive 
contributions  to  the  subject  of  cholera  which  are  at  pres- 
ent filling  the  columns  of  the  secular  and  medical  press. 
The  inquiring  reader  begins  each  article  with  fi-esh  ex- 
pectation of  enlightenment.  But  all  the  knowledge  of 
our  most  erudite  sanitarians  and  eminent  pathologists 
seems  reducible  to  this  :  that  cholera  is  communicable 
and  portable,  that  it  affects  filthy  localities  and  people, 
that  rigid  municipal  and  personal  sanitation,  and  a  dis- 
criminating use  of  quarantine  measures  should  be  en- 
forced. 

That  there  is  some  kind  of  a  cholera  germ  all  believe, 
but  what  it  is  none  know.  It  has  been  very  generally 
agreed  that  this  germ  requires  a  special  nidus  for  its  de- 
velopment, that  for  the  spead  of  cholera  there  must  be 
a  something  which  has  been  called  ''  epidemic  constitu- 
tion." But  modem  sanitary  reformers  assert  that  this 
so-called  "  constitution  "  is  only  an  intensity  of  filth.  In 
the  city  of  Hygeia  there  are  no  epidemic  constitutions. 
And  such  is  the  safest  practical  view  to  take,  whether  it 
be  an  absolutely  tme  one  or  not. 

As  for  quarantine,  some  dissenting  voices  here  echo 
the  English  opinion  as  to  its  non-utility.  We  had  best 
go,  however,  by^what  our  past  experience  has  taught  us, 
and  that  is,  that  quarantine  is  a  valuable  means  of  pro- 
tection. It  should  be  applied  sensibly  and  with  discrim- 
ination, however,  and  should  bear  most  of  all  upon  the 
immigrants,  who  have  heretofore  been  the  primary  dis- 
pensers of  the  hypothetical  bacilli  of  cholera  in  the 
United  States. 

The  cholera  germ  may  be  positively  discovered  any 
day,  meanwhile  Koch's  bacillus  theory  has  not,  as  was  first 
hoped,  thrown  any  flood  of  light  upon  cholera  problems, 
and  as  for  its  prophylaxis  it  is  still  expressed  in  these  three 
phrases:  Rational quaraniiney  municipal  cleanliness^ per- 
sonal hygiene.  

REGULATING  MEDICAL  PRACTICE  IN  MISSOURI. 
The  stirring  attack  made  some  time  ago  by  Dr.  King 
upon  quackery  in  Missouri  has  already  borae  fmit. 
The  Sute  created  a  board  of  health  in  July,  1883,  and 
gave  to  it  a  certain  amount  of  power  in  regulating  medi- 
cal practice  and  putting  down  quackery. 


The  provisions  of  the  law  are  much  like  those  of  Illinois, 
and  it  contains  the  '*  itinerant  quack  "  section  compel- 
ling travelling  venders  of  nostrums  and  persons  publidy 
professing  and  advertising  to  cure  disease  to  pay  a 
monthly  license  of  $100  Attempts  to  enforce  such  a 
section  naturally  create  some  trouble,  and  we  learn  from 
the  Kansas  City  Medical  Index  that  the  efibrts  of  the 
State  Board  to  enforce  the  law  in  that  place  have  been 
violently  opposed  by  the  quacks  and  the  public  presfr- 
two  social  forces  which  often  work  harmoniously  together 
by  reason  of  the  profits  of  advertising. 

The  Index  puts  the  matter  very  fairly  :  "The  law  call- 
ing  into  existence  the  Board  and  also  governing  its  actioD 
was  enacted  for  the  benefit  of  the  public,  and  not  for  the 
benefit  of  physicians,  as  some  of  the  papers  try  to  repre- 
sent These  papers  receive  large  amounts  of  money 
from  these  pretending  doctors  for  advertising,  and  hence 
they  cry  out  because  their  ox  is  gored." 

We  would  remind  the  Index  also  that  the  creation  and 
enforcement  of  regulating  laws  is  based  not  only  upon 
the  need  of  protecting  the  public  health  and  of  purifying 
the  medical  body,  the  State  of  Missouri  obliges  medtctl 
men  to  report  all  births  and  deaths,  thus  giving  to  &em 
sm  official  duty  and  in  a  measure  an  official  position. 
The  State,  on  this  ground,  can  rightly  insist  on  passing 
upon  the  qualifications  of  its  medical  practitioners. 


THE   MEETING  OF  THE  NEW  YORK   STATE   MEDICAL 
ASSOCIATION. 

The  New  York  State  Medical  Association  held  a  pleas- 
ant and  harmonious  meeting  in  this  city  during  the  past 
week.  The  attendance  was  very  good,  especially  of  out- 
of-town  phjTsicians.  The  medical  contributions,  thou^ 
not  destined  to  make  new  epochs  in  science,  were,  many 
of  them,  of  excellent  character  and  likely  to  reflect  credit 
upon  the  State.  Indeed,  it  is  a  matter  of  some  pride  to 
New  Yorkers  to  find  that  the  State  can  creditably  sap- 
port  and  contribute  to  two  organizations. 

New  York  Cityis  a  pleasant  and  alluring  place  for 
medical  meetings,  and  so  long  as  the  Association  assem- 
bles here,  and  does  good  work,  it  will  receive  support 
from  and  be  a  source  of  benefit  to  its  members.  The 
issue  which  started  it  is  already  nearly  forgotten,  and 
sensible  men  recognize  that  its  practical  significance  is 
now  trivial.  It  is  not  upon  any  point  in  casuistry  diat 
the  Association  can  stand  or  hold  together,  but  upon  its 
merits  as  a  medical  society. 


THE  UTILITY  OF  QUARANTINE  IN  CHOLERA. 

Dr.  John  H.  Rauch  takes  the  view  that  cholera  is  pre- 
eminently a  quarantinable  disease,  because  "  no  single 
case  of  cholera,  no  one  shipload  of  cases  has  ever  yetsof* 
ficed  to  establish  an  epidemic  of  Asiatic  cholera  on  this 
continent  It  has  only  been  after  repeated  importationi 
of  the  contagion  in  the  persons  of  thousands  of  inmup 
grants  and  in  their  infected  baggage  and  household  goodf 
tiiat  it  has  effected  a  lodgment,  and  has  reproduced  itself 
and  multiplied  into  an  active  epidemic  agency." 

In  proof  of  this  he  cites  the  history  of  previous  epi- 
demics of  cholera  in  this  country.  Dr.  Rauch  appean  to 
forget,  however,  that,  even  if  his  factsjare  correct  for  the 
United  States,  in  the  past  .they  do  not  fit  the  history  of 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


571 


cholera  elsewhere.  And  the  proposition  that  an  epi- 
demic of  cholera  can  not  be  started  by  a  single  case  is 
utterly  untenable. 

For  all  this  cholera  is  undoubtedly  quarantinable,  and 
if  Congress  will  do  its  duty  there  is  a  good  chance  that 
the  disease  may  be  kept  from  us. 

Death  of  Dr.  Samuel  M.  Bemiss. — ^We  regret  to  an- 
nounce the  death  on  November  17th  of  Dr.  Samuel  M. 
Bemiss.  He  was  Professor  of  the  Theory  and  Practice 
of  Medicine  and  of  Clinical  Medicine  in  the  University 
of  Louisiana,  and  during  the  epidemic  of  1878  was  the 
representative  of  the  National  Board  of  Health  in  New 
Orleans.  He  was  sixty-three  years  old,  and  served  as  a 
surgeon  in  the  Confederate  Army.  He  was  a  graduate 
of  the  medical  department  of  the  University  of  New  York. 

Cholera  and  Rags. — Experience  shows  that  cholera 
has  been  brought  to  this  country  heretofore  by  passengers, 
and  especially  immigrants  and  their  baggage.  It  is  very 
certain,  however,  that  the  disease  can  be  carried  by  rags 
and  this  source  of  danger  ought  to  be  carefully  watched. 
A  complete  embargo  on  rags  from  all  ports  or  even  a 
compulsory  disinfection  of  them  is  unnecessary. 

State  Medical  Association  Notes. — It  may  happen 
that  the  New  York  State  Medical  Association,  which  met 
in  this  city  during  the  present  week,  will  prove  to  be  an 
agent  of  value  to  the  State  Society  and  the  profession  at 
large.  At  least  the  Society  may  learn  from  it  several 
lessons.  One  of  these  is  that  New  York  City  is  an  ex- 
cellent place  in  which  to  hold  annual  medical  meetings. 
Taking  it  all  in  all,  the  means  of  reaching  it  are  as  good, 
if  not  better,  than  those  of  reaching  Albany,  while  the 
acconunodations  and  general  attractions  are  superior. 

The  Association  has  shown  also  that  by  energetic  work 
papers  can  be  obtained  from  physicians  all  over  the  State, 
and  that  the  bulk  of  the  literaiy  work  need  not  fall  upon 
New  York  City. 

As  for  the  Association  doing  any  injury  to  the  State 
Society,  this  is  not  to  be  thought  of,  and  is  not  probably 
intended  except  by  the  embittered  few.  The  rural  practi- 
tioners throughout  the  State  recognize  the  slight  practical 
importance  of  the  ethical  issue,  and  feel  no  ill-will  toward 
the  Mother  Society,  which  has  what  the  Association  has 
not,  a  past.  Perhaps  this  is  in  noway  better  shown  than 
by  the  indifference  felt  toward  the  fact  (for  it  is  a  fact  of 
which  there  is  absolute  proof)  that  the  President,  Dr. 
Didama,  has  consulted  with  homoeopaths,  excusing  the 
practice  under  the  disingenuous  plea  that  he  treats  the 
homoeopaths  who  call  him  in  as  nurses. 

The  papers  read  at  the  Association  were  in  many  cases 
too  long,  and  little  chance  was  given  for  profitable  discus- 
sion. The  question  of  section  meeting  was  naturally 
raised ;  it  is  one  that  the  State  Society  has  considered 
and  will  doubtless  have  in  time  to  adopt 

Dr.  Samuel  A.  Fisk,  aged  sixty-three,  ex-President  of 
the  Massachusetts  Medical  Society.  Lecturer  at  Smith 
College,  and  Trustee  of  the  Clarke  Institute  for  Deaf 
Mutes,  died  at  Northampton,  on  November  i6thy  of  or- 
ganic disease  of  the  heart. 


Pennsylvania  Hospitai On  November  loth,  says 

the  Philadelphia  Medical  Times,  a  notable  ceremony  was 
held  at  the  Pennsylvania  Hospital,  the  occasion  being 
the  restoration,  after  an  absence  of  fifty  years  in  another 
department  of  the  institution,  of  the  celebrated  picture  of 
Christ  Healing  the  Sick  in  the  Temple,  which  had  been 
originally  painted  for  and  presented  to  the  hospital  by 
Benjamin  West. 

A  Mistake. — Our  usually  careful  contemporary,  Tke 
Boston  Medical  and  Surgical  Journal,  states  that  the 
New  York  County  Medical  Society  unanimously  voted 
to  admit  to  membership  two  homoeopaths.  This  is  a 
mistake.  The  gentlemen  in  question  have  distinctly  re- 
nounced dogmatic  horiiceopathy. 

Death  of  a  Physician  from  Self-Administration 
OF  Chloroform. — It  is  a  practice  which  we  fear  is  not 
very  uncommon  among  physicians  to  inhale  chloroform 
when  suffering  from  severe  pains.  The  Weekly  Medical 
Review  reports  the  death  through  this  practice  of  Dr.  C. 
M.  Whiting,  of  Ogle  County,  111.  Reference  is  made 
also  to  the  death  some  years  ago,  in  a  similar  way,  of  a 
young  physician  who  had  just  graduated  and  was  prac- 
tising in  the  suburbs  of  Chicago. 

The  Cholera  in  Paris. — Cable  reports  show  that 
from  forty  to  fifty  deaths  from  cholera  occur  daily  in 
Paris.  This  represents  about  one  hundred  cases  daily, 
and  indicates  a  considerably  less  prevalence  of  cholera 
than  often  exists  of  diphtheria,  or  typhoid  fever.  There 
is  no  panic,  and  the  disease  at  date  of  writing  is  declining. 

A  Crematory  for  New  York. — The  comer-stone 
of  a  crematory  temple  was  laid  at  Mount  Olivet,  Long 
Island,  on  November  20th.  The  proposed  edifice  is 
being  built  by  the  United  States  Cremation  Company, 
which  expects  to  complete  its  work  by  February  next 
Twenty  bodies  already  await  incineration.  The  cost  of 
the  building  is  about  $10,000,  that  of  incineration  $10 
to  $25.  The  building  is  in  the  shape  of  a  Greek  temple 
40  by  72  feet  Incineration  will  take  place  at  a  tem- 
perature of  about  2,500^  F.  It  will  require  about  forty 
minutes  per  hundred  pounds  of  the  subject,  and  will 
leave  about  four  per  cent,  in  weight  of  a  pure  pearly  ash. 
No  smoke  will  be  visible  and  no  odor  perceptible  during 
incineration.  The  basement  will  also  contain  a  refrigi- 
darium,  where  bodies  may  be  kept  when  desired  await- 
ing the  arrival  of  friends  from  a  distance ;  also  a  calidarium 
for  cases  of  possibly  suspended  animation,  the  high  tern* 
perature  of  which  will  induce  speedy  evidences  of  life  or 
death,  as  the  case  may  be.  There  will  be,  also,  in  the 
basement  an  culicularium,  or  urn  room,  and  an  ateliei:. 
This  last  will  be  used,  also,  for  making  autopsies,  which 
will  be  required  in  all  cases  wherein  it  is  not  clear  that 
death  is  the  result  of  natural  causes.  The  body  of  the 
building,  or  the  ground  floor,  will  be  fitted  up  as  a  chapel, 
where  any  service  desired  may  be  held. 

A  Contribution  Toward  the  Medical  Education 
of  Women. — ^The  Calcutta  Medical  College  has  received 
from  the  Maharani  Surnamayi  of  Cossim  Bazaar,  Moor- 
shedabad,  one  of  the  millionaires  of  Bengal,  a  lakh  and  a 
half  of  rupees,  $75,000,  toward  the  scheme  for  providing 
separate  classes  for  female  medical  students  at  the  Col- 
lege, and  has  promised  to  increase  the  gift  to  eight  lakhs 
($400,000),  should  a  separate  college  be  provided. 


572 


THE   MEDICAL  RECORD. 


[November  22,  1884, 


^f^avts  0t  SacUtUs. 


NEW  YORK  STATE   MEDICAL  ASSOCIATION. 

jFirsf  Annual  Session^  held  in  New  York  City^  November 
18,  19,  and  20,  1884. 

Tuesday,    November    i8th — First    Day — Morning 

Session. 
The  Association  was  called  to  order  at  9.45  a.m.,  by 
Dr.  Gouley.  The  Secretary  announced  the  registra- 
tion of  Fellows.  The  Chairman  of  the  Committee  of 
Arrangements,  Dr.  Gouley,  then  welcomed  the  Associa- 
tion in  a  short  address. 

The  President  also  delivered  an  address,  and  an- 
nounced  the  following  as  the  Committee  on  Scientific 
Contributions :  Dr.  E.  S.  F.  Arnold,  of  New  York 
County ;  Dr.  Simeon  T.  Clark,  of  Niagara  County ;  Dr. 
William  Gilles,  of  Franklin  County ;  Dr.  George  W. 
Avery,  of  Chenango  County ;  Dr.  J.  C.  Hannon,  of 
Rensselaer  Count)'. 

The  Secretary  then  read  the  report  of  the  Council,  and 
on  motion  of  Dr.  Arnold  the  report  was  adopted 

Representatives  from  the  Vermont  Medical  Society  and 
the  Pennsylvania  State  Society  were  received. 

The  annual  report  of  the  Treasurer  was  made  and  ac- 
cepted. 

The  special  committee  on  the  organization  of  district 
associations  reported  in  favor  of  the  establishment  of  five 
such  associations.  After  some  discussion  the  report  was 
adopted. 

THE   ADDRESS    ON   SURGERY 

was  then  delivered  by  Dr.  E.  M.  Moore,  of  Monroe 
County. 

The  object  of  the  paper  was  not  to  enumerate  all  the 
late  discoveries  in  surgery,  but  to  dwell  upon  a  few  facts 
in  connection  with  transfusion  of  blood.  Various  methods 
of  transfusion  have  been  proposed,  but  none  have  given 
general  satisfaction.  When  first  discovered  great  ex- 
pectations were  founded  on  it,  but  on  account  of  some 
unfortunate  accidents  the  practice  was  condemned.  That 
it  has  great  value  cannot  be  disputed.  All  surgical 
practices  to  be  successful  must  be  simple.  Complicated 
apparatus  is  to  be  discarded  and  some  simple  surgical 
device  instituted.  In  1657  Sir  Christopher  Wren  sug- 
gested the  possibility  of  this  practice.  At  first  it  was 
tried  only  on  animals.  These  experiments  were  the 
natural  outcome  of  Harvey's  discovery.  Some  denounced 
the  practice  as  legalized  murder.  After  1668  the  interest 
seems  to  have  disappeared.  Up  to  18 19  only  arterial 
blood  was  used,  but  since,  all  kinds  have  been  employed. 
The  blood  of  those  species  nearest  of  kin  has  been  most 
successfully  used.  Transfusion  from  the  lamb  to  man 
has  been  more  or  less  successful,  but  blood  obtained  from 
the  same  species  answers  best  We  cannot  obtain  arterial 
blood  from  human  beings,  and  hence  must  take  venous. 
To  avoid  danger  from  coagula,  defibrinated  blood  is 
sometimes  used.  The  question  was  raised  whether  this 
was  true  blood,  and  answered  in  the  negative  by  the 
author.  Various  medicated  substances  have  sometimes 
been  used,  but  blood  answers  best  The  distention  of 
the  vessels  by  simple  saline  solutions  has  at  times  given 
temporarily  great  benefit  The  principal  dangers  of 
transfusion  are  from  ingress  of  air  and  formation  of 
coagula.  The  special  point  made  by  the  author  was 
that  the  time  of  operation  should  be  short  and  definite. 
Most  operators  tsdce  from  two  to  three  minutes.  The 
operation  should  never  exceed  the  limit  of  one  minute. 
There  is  a  period  of  transition  from  normal  blood  to  ab- 
normal during  the  passage  through  the  canula,  hence  the 
absolute  rule  of  shortness  of  time.  An  assistant  should 
read  off  ten  seconds,  twenty  seconds,  thirty  seconds,  etc., 
during  the  operation.  The  transference  of  venous  blood 
is  a  difficult  problem.  A  longitudinal  slit  should  be 
made  in  the  vessel  and  the  syringe  held  perpendicularly. 
The  writer  then  exhibited  a  canula  and  mandrel  devised  by 


himself,  which  has  been  successfully  used.  By  rounding 
the  edges  coagulation  is  prevented  The  instrument  can 
be  extemporized  in  case  of  emergency  by  using  a  goose, 
quill  for  a  canula.  Dog's  blood  coagulates  quicker  than 
human  blood,  but  the  author  had  succeeded  in  experi- 
ments with  his  instrument  upon  the  dog.  Transfusion  is 
especially  indicated  after  sudden  great  losses  of  blood, 
and  in  anaemia  from  exhaustive  discharges.  It  does  not 
seem  to  avail  in  the  exhaustion  from  phthisis  and  like 
diseases. 

Dr.  Townsend,  of  Genesee  County,  opened  the  dis- 
cussion  by  narrating  an  instance  in  which  Dr.  Moore  and 
himself  had  practised  transfusion  in  fifty  seconds.  The 
operation  was  successful  at  the  time,  but  the  patient  after- 
ward died  of  exhaustion.  It  was  then  moved  and  carried 
to  postpone  the  further  discussion  until  after  the  reading 
of  Dr.  Hutchinson's  paper  on  transfusion. 

Dr.  Detmold,  the  president  of  the  County  Medical 
Association  was  then  introduced  to  the  meeting.  He 
stated  the  objects  of  the  Association  and  announced  tiie 
titles  of  the  papers  that  had  been  read  during  the  past 
year.  It  was  carried  to  transfer  these  papers  to  the 
Council  of  the  State  Association. 

A  recess  was  next  taken,  during  which  there  were 
meetings  of  the  five  district  associations,  in  which  the 
time  and  place  of  next  meeting  were  appointed  and 
secretaries  named. 


Afternoon  Session. 

The  Association  was  called  to  order  by  The  President, 
who  remarked  that  it  might  be  necessary,  owing  to  the 
large  number  of  papers  announced,  to  divide  the  work 
between  two  sections,  a  medical  and  a  surgical.  This 
would  be  determined  by  the  members  during  the  present 
session. 

The  first  communication  was  by  Dr.  J.  C.  Hutchin- 
son, of  Kings  County,  upon 

TRANSFUSION. 

Although  this  operation  had  been  practised  five  hun- 
dred years  ago,  it  was  still  but  rarely  undertaken,  and 
had  certainly  not  fulfilled  its  early  promises  of  utility  and 
ready  applicability.  The  present  epidemic  of  cholera  in 
Europe  has  invested  the  subject  of  the  transfusion  of 
blood  and  other  substances  with  fresh  interest,  and  the 
author  believed  that  the  procedure  might  now  become 
popularized  were  the  means  of  its  application  simplified, 
the  dangers  diminished,  and  the  apparatus  improved. 
An  instrument  was  then  exhibited  which  seemed  to  fulfil 
the  indications  of  simplicity  and  ease  of  management  It 
consisted  of  a  glass  cylinder,  terminating  below  in  a  per- 
forated metal  cap,  and  above  in  a  rubber  stopper  through 
which  was  inserted  a  thermometer.  The  side  of  the  cyl- 
inder was  marked  off  in  sections  of  half  an  inch.  Sur- 
rounding the  cylinder  was  a  double  fubber  jacket  with  a 
slit  on  one  side  to  permit  a  view  of  the  markings  on  the 
glass.  This  rubber  jacket  was  to  be  filled  with  hot  water 
(of  140^  to  150^)  in  order  to  keep  the  injecting  material 
warm.  A  rubber  tube  is  fastened  to  the  lower  end  of  the 
cylinder  by  one  extremity,  the  other  extremity  being  at- 
tached to  a  canula.  This  canula  is  provided  with  a  stop- 
cock by  means  of  which  the  rapidity  of  flow  of  the  trans- 
fused material  is  regulated.  The  author  had  not  seen 
the  instrument  exhibited  by  Dr.  Moore  before  writing 
his  paper,  but  thought  it  excellent,  and  should  himsdf 
always  use  the  canula  there  shown. 

It  was  formerly  supposed  that  the  reviving  power  of 
transfused  blood  lay  in  its  corpuscles,  but  this  has  been 
shown  to  be  erroneous,  for  the  corpuscles  are  quickly  de- 
stroyed. Recent  experiments  have  demonslrated  that 
the  principal  thing  necessary  is  to  restore  the  volume  of 
the  circulating  fluid.  The  danger  after  hemorrhage  lies 
in  the  disturbed  relations  of  the  blood-vessels  to  tfaeir 
contents,  hence  it  is  not  necessary  to  employ  blood,  and 
indeed  a  saline  solution  is  preferable.  Experiments  have 
shown  that  the  blood  of  another  species,  when  injected 


November  22,  1884.] 


THE   MEDICAL  RECORD. 


573 


into  the  circulation,  may  cause  acute  nephritis  and  im- 
peril life.  Milk  is  objectionable,  for  the  undigested 
casein  when  transfused  into  the  blood  is  unassimilable, 
and  the  butyric  elements  may  give  rise  to  chyluria  and 
other  disturbances.  Experiments  made  upon  animals 
bled  to  syncope  have  shown  that  consciousness  could  be 
restored  and  life  preserved  by  the  injection  of  simple 
saline  solutions,  and  the  value  of  this  material  for  trans- 
fusion has  also  been  demonstrated  clinically.  The  au- 
thor quoted  the  statistics  of  the  transfusion  of  saline  solu- 
tions, and  related  five  cases  in  which  he  himself  had 
employed  this  method  in  the  resuscitation  of  cholera  pa- 
tients. All  the  patients  were  in  the  stage  of  collapse, 
indeed  were  moribund,  "the  temporary  effects  of  the 
transfusion,  however,  were  most  marked,  although  all  the 
patients  eventually  died. 

The  temperature  of  the  solution  should  be  not  lower 
than  98.5°  and  not  above  Io5^  The  quantity  used  should 
be  from  twelve  to  twenty-four  ounces.  But  one  of  the 
roost  important  points  in  the  operation  is  the  rapidity 
with  which  the  ^uid  is  allowed  to  enter  th^  vessels ;  the 
rate  should  not  bv  above  one  ounce  a  minute.  The  me- 
dian basilic  vein  is  v  -ually  selected  to  receive  the  trans- 
fused material,  though  lately  arterial  injections  have  been 
urged  as  offering  equal  facility,  and  obviating  the  chief 
danger  of  embolism  of  the  brain  (since  all  organic  parti- 
cles or  clots  are  detained  in  the  systemic  capillaries),  of 
the  entrance  of  air,  or  of  overpowering  the  heart  by  a 
sudden  afflux  of  fluid.  In  concluding,  the  author  said 
that  if  the  results  already  obtained  by  transfusion  should 
be  confirmed  by  further  experience,  the  operation  was  one 
deserving  of  more  honor  than  it  had  as  yet  obtained 

Dr.  Rochester,  of  Erie  County,  related  a  case  in 
which  a  speedy  and  permanent  improvement  had  fol- 
lowed upon  the  transfusion  of  less  than  two  ounces  of 
blood,  and  he  thought  that  this  demonstrated  that  it  was 
not  alone  to  the  quantity  of  fluid  that  the  good  effects  of 
transfusion  should  be  referred,  but  that  the  nature  of  the 
material  employed  was  also  to  be  considered.  He  also 
had  seen  wonderful  improvement  following  the  injection 
of  saline  solutions  in  the  stage  of  collapse  of  cholera, 
but  these  results  were  only  temporary,  for  the  patient? 
invariably  died. 

The  next  paper  read  was  by  Dr.  Alfred  I^  Carroll, 
of  Richmond  County,  on  the 

DURATION  OF  CONTAGIOUSNESS   AFTER  ACUTE  INFECTIOUS 
DISEASES. 

The  object  of  his  remarks,  the  speaker  said,  was  rather 
to  direct  his  hearers'  attention  to  the  importance  of 
studying  this  subject  and  recording  their  observations  by 
the  plan  of  collective  investigation,  than  to  present  any 
certain  data  upon  which  they  could  yet  base  their  con- 
duct in  any  given  case.  The  subject  was  one  that  had 
received  but  scant  attention,  and  upon  which  there  was 
but  little  unanimity  of  opinion,  and  yet  a  little  consider- 
ation would  show  how  important  it  was  to  be  able  to  de- 
termine just  when  the  isolation  of  a  convalescent  might 
with  safety  be  removed.  The  author  had  addressed  a 
communication  to  a  number  of  well-known  medical 
teachers  and  practitioners,  in  order  to  ascertain  whether 
there  were  any  consensus  of  opinion  on  this  point,  and 
he  presented  to  his  hearers  a  condensed  summary  of  the 
answers  obtained.  As  regards  small-pox,  nearly  all  of 
his  correspondents  were  agreed  that  there  was  dan- 
ger of  contagion  until  all  the  crusts  had  been  removed, 
although  one  stated  his  belief  that  there  was  little  danger 
to  be  apprehended  from  the  scabs  on  the  palms  and 
soles,  provided  there  were  none  remaining  on  the  other 
parts  of  the  body.  In  respect  to  the  other  contagious  dis- 
eases there  was  less  accord.  In  typhoid  fever  and  in  chol- 
era it  was  the  general  opinion  that  the  contagion  resided 
in  the  discharges,  and  that  the  danger  ceased  when  con- 
valescence had  been  established.  Many  of  the  corre- 
spondents, with  whom  the  author  also  agreed,  regarded 
filth-poison  as  of  prime  importance  in  diphtheria,  and 


doubted  the  existence  of  a  direct  personal  contagious- 
ness. Yet  one  writer  maintained  that  there  was  danger 
as  long  as  any  trace  of  inflammation  remained.  In 
measles  one  would  release  the  patient  from  quarantine  as 
soon  as  the  fever  and  eruption  had  disappeared,  while 
others  would  prolong  the  period  of  isolation  to  from  one 
to  three  weeks  after  desquamation  had  ceased.  The 
greatest  diversity  of  opinion  existed  in  regard  to  scarla- 
tina. Many  released  the  patients  as  soon  as  desqua- 
mation had  ceased  and  a  bath  had  been  given  ;  others 
confined  them  for  a  period  varying  from  six  to  eight 
weeks.  The  author  had  found  in  some  cases  that  no 
contagion  occurred  even  when  the  children  mingled 
with  their  playmates  before  the  period  of  desquamation 
was  over.  He  thought  that  this  fact  was  to  be  explained 
by  assuming  that  the  last  scales  thrown  off  were  not  in- 
fectious, but  were  the  expression  of  a  secondary  derma- 
titis, the  scales  first  appearing  being  the  ones  that  con- 
tained the  poison. 

Dr.  John  S.  Jamison,  of  Steuben  County,  then  read 
a  communication  on 

chronic  intestinal  CATARRH. 

The  most  frequent  cause  of  this  condition  is  an  improper 
diet,  as  regards  either  quantity  or  quality.  Another 
potent  factor  in  the  production  of  the  disease  is  found  in 
meteorological  conditions — a  prolonged  high  tempera- 
ture or  a  change  to  cold,  damp  weather.  It  may  arise 
from  impaired  stomach  digestion,  from  disease  of  the 
liver  or  pancreas,  or  from  any  condition  causing  obstruc- 
tion to  the  portal  circulation.  The  malarial  poison  is 
another  occasional  etiological  factor.  An  acute  diarrhoea 
is  often  neglected  and  may  then  pass,  after  successive 
attacks,  into  a  chronic  intestinal  catarrh.  The  symptoms 
of  this  condition  are  not  always  sharply  defined,  for 
diarrhoea  is  not  necessarily  present,  and  there  may  be  no 
severe  pain.  There  is  often  a  dull  sense  of  pressure  and 
abdominal  fulness.  The  author  had  frequently  observed 
a  displacement  downward  of  the  transverse  colon,  and 
he  regarded  it  as  a  sign  of  considerable  value  in  the 
diagnosis  of  this  disease.  Sometimes  mucus,  in  coherent 
masses  or  even  in  the  shape  of  intestinal  casts,  is  passed 
at  stool.  In  the  treatment  the  author  regarded  pepsine 
and  pancreatine  as  of  great  utility. 

A  paper  by  Dr.  Frederick  Hyde,  of  Cortland 
County,  was  read  by  title  only,  the  author  being  absent 

Dr.  Edward  R.  Squibb,  of  Kings  County,  then  fol- 
lowed with  a  paper  entitled 

THE  modern  progress  OF  MATERIA  MEDICA. 

The  author  did  not  refer  to  the  introduction  of  new 
remedies,  now  becoming  so  fashionable,  but  rather 
wished  to  consider  the  elements  of  progress  in  the  treat- 
ment of  disease  among  that  large  class  of  intelligent  and 
practical  physicians  who  read  much  but  write  little,  but 
who  are  none  the  less  good,  sound,  and  sensible  practi- 
tioners. The  progress  of  materia  medica  among  these 
men  cannot  be  learned  from  their  writings,  since  they 
do  not  write,  but  is  to  be  judged  of  by  knowing  the  drugs 
which  they  order  and  use.  Medical  men  now  realize  the 
fact  that  their  success  in  their  profession  depends  upon 
their  utility  to  the  public  ;  they  must  direct  their  -energies 
to  the  prevention  of  disease,  to  its  management  when  it 
occurs,  and  to  the  reparation  of  its  ravages.  The  phy- 
sician does  not  now  rest  content  with  a  diagnosis,  but 
seeks  as  far  as  he  may  to  conduct  his  case  to  a  success- 
ful ending.  We  hear  less  and  less  of  expectancy  in  the 
treatment  of  disease ;  indeed  the  danger  now  is  of  rushing 
into  the  opposite  extreme  by  trying  all  the  new  remedies 
that  are  spoken  of.  The  author  pictured  the  armamen- 
tarium of  a  physician  in  one  of  the  new  Western  towns ; 
this  consists  of  a  thermometer,  urinometer,  litmus  paper, 
often  a  plain  serviceable  microscope,  and  sometimes  even 
a  sphygmograph.  He  has  a  good  selection  of  some 
twenty  or  thirty  of  the  standard  remedial  agents,  but  few 
non-oflicinal  drugs  are  found  in  his  stock.  More  pharma- 
copoeias are  sold  now  than  formerly,  and  physicians  are 


574 


THE  MEDICAL  RECORD. 


[November  22, 1884. 


learning  to  make  their  own  tests  and  to  judge  for  them- 
selves of  the  parity  of  the  drugs  supplied  to  them.  Few 
physicians  nowadays  undertake  <*  cures,"  but  they  en- 
deavor to  conduct  the  disease  to  a  successful  issue.  Few 
believe  that  drugs  cure  diseases,  and  hence  they  seek  to 
manage  their  cases  according  to  the  indications  as  they 
arise.  Another  advance  that  has  been  made  in  the  last 
few  years  is,  that  practitioners  are  learning  to  throw  off 
the  trammels  of  arbitrary  doses.  They  now  look  only  for 
effects  from  remedial  agents,  and  they  accordingly  push 
the  drug  until  they  obtain  these  effects.  The  use  of  in- 
dicating doses  for  drugs,  the  writer  thought,  will  in  the 
future  be  only  to  show  where  we  are  to  start  in  their  ad- 
ministration, the  stopping-point  being  different  in  differ- 
ent cases,  and  to  be  determined  only  by  observation  of 
the  effects  produced.  Physicians  use  fewer  drugs  than 
formerly,  but  those  that  they  do  use  are  more  effectual. 
The  combination  of  many  agents  in  one  prescription  is 
less  frequently  resorted  to.  The  form  of  the  agent  now 
used  is  also  worthy  of  note.  The  dilate  and  uncertain 
preparations  are  being  called  for  with  less  and  less  fre- 
quency, and  the  fluid  extracts,  as  the  most  concentrated 
and  most  reliable  forms,  are  growing  daily  in  favor. 
There  is,  however,  a  tendency  to  the  use  of  alkaloids,  of 
the  so-called  active  principles  of  drugs,  which  the  author 
did  not  approve.  The  active  principles  so-called,  he 
maintained,  are  not  the  same  as  the  drug,  for  they  are 
often  produced  by  some  chemical  change  occurring  in  the 
course  of  their  manufacture.  They  are  furthermore  not 
always  permanent,  but  are  liable  to  split  up  and  form 
new  chemical  compounds  with  totally  different  effects. 
Thus,  the  author  concluded,  although  in  the  main  the 
progress  has  been  in  the  right  direction,  yet  not  all  the 
changes  of  late  have  been  improvements. 

Dr.  W.  H.  Robb,  of  Montgomery  County,  read  a 
paper  on  the 

MANAGEMENT  OF  CRIMINAL  ABORTION. 

Control  hemorrhage  as  soon  as  possible  with  ergot  and 
digitalis  given  hypodermically  and  in  full  doses.  Stimu- 
lants should  be  given  by  the  same  method  until  the  pa- 
tient has  rallied.  The  ergot  should  be  given  as  soon  as 
the  patient  is  seen,  and  should  be  continued  until  the 
uterus  has  contracted  and  the  ovum  has  been  entirely 
removed.  Locally,  various  astringents,  as  ice,  tincture 
of  iodine,  hot  carbolized  solutions,  and  other  remedies, 
may  be  used.  When  these  means  fail  to  control  the 
hemorrhage,  the  tampon  should  be  introduced.  The 
tampon  should  be  removed  every  six  hours,  and  its  re- 
moval should  be  followed  by  a  hot  carbolized  injection. 
The  injections  are  best  given  by  introducing  a  soft 
rubber  tube  into  the  uterus.  The  Fountain  syringe  is 
the  best,  as  by  its  use  no  force  can  be  exerted  and  no  air 
can  enter  the  organ.  The  womb  should  be  emptied  as 
soon  as  possible,  so  that  all  danger  of  decomposition 
may  be  prevented.  The  safest  and  most  efficient  instru- 
ment in  removing  the  ovum  is  the  finger.  If  the  cervix 
is  not  dilated,  tents  should  be  used.  The  removal  of  the 
ovum  should  be  followed  by  a  hot  douche. 

Dr.  Vandewaker,  of  Syracuse  said  the  danger  in  abor- 
tion before  the  third  month  is  due  to  loss  of  blood  and 
poisoning  from  decomposition.  He  had  never  seen  a 
good  result  from  the  use  of  ergot  in  criminal  abortion. 
The  machinery  of  the  uterus  is  not  fully  developed  before 
the  third  month,  hence  the  uterus  does  not  contract 
firmly,  but  spasmodically.  If  the  physician  is  called  late 
at  night,  and  no  other  means  are  at  hand,  the  tampon 
may  be  used ;  but  it  should  never  be  used  unless  abso- 
lutely necessary.  The  quickest  way  to  stop  the  hemor- 
rhage is  to  relieve  the  uterus  of  its  contents. 

Dr.  Moses  C.  White,  of  New  Haven  said  the  action 
of  ergot  in  abortion  at  the  third  month  is  not  to  expel  the 
contents,  but  to  contract  the  uterus  and  thus  prevent  its 
expulsion.  He  uses  ergot,  not  to  bring  on  but  to  prevent 
abortion. 

Pr.  Sabine,  of  West  Point,  explained  the  dangers  of 


using  the  tampon,  and  gave  the  history  of  a  case  of 
rupture  of  the  fundus  of  the  uterus,  followed  by  the  death 
of  the  patient,  due  to  its  use.     Tampons  are  very  danger- 
ous unless  used  with  great  caution. 
A  paper  on 

intestinal  obstruction, 

by  Dr.  Avery  Segur,  of  Kings  County,  was  then  read  by 
title. 

Dr.  Charles  Bulkley,  of  Monroe  County,  read  a 
paper  on 

chronic  mercurial  poisoning. 

He  presented  the  history  of  a  case  in  his  own  practice  in 
which  the  poisoning  was  due  to  wearing  a  hard  robber 
plate  with  false  teeth.  All  the  symptoms  were  present 
while  the  plate  was  used,  but  disappeared  when  its  use 
was  discontinued.  He  also  presented  the  histoiies  of 
several  other  cases  due  to  the  same  cause. 
Dr.  R.  H.  Sabin  read  a  paper  on 

A   CASE   OP  ACUTE   LEAD  POISONING  RESULTING  FATAUY. 

The  case  was  that  of  a  young  man  who  was  poisoned 
while  working  in  a  paint  shop.  There  was  a  rapid  infus- 
ion into  the  brain,  causing  insensibility,  and  this  was  fol- 
lowed by  a  peculiar  algid  condition. 

The  session  then  adjourned  until  evening. 

Evening  Session. 

Dr.  H.  E.  Mitchell,  of  Rensselaer  County,  read  a 
paper  on 

ERRORS    OF    REFRACTION,    THE    IMPORTANCE    OF  THEIR 
RECOGNITION  AND  CORRECTION   IN   EARLY  LIFE. 

Defects  of  eyesight  due  to  errors  of  refraction  are  on  the 
increase.  A  description  of  the  coats  of  the  eye  and  the 
contents  of  the  ball  was  then  ^ven.  Myopia  may  be  ac- 
quired or  congenital.  Statistics  show  an  increase  of  the 
congenital  form.  The  acquired  is  the  most  important  to 
consider.  The  minus  or  double  concave  glass  should  be 
used.  Myopia  in  young  persons  shows  a  tendency  to 
increase. 

Dr.  K  D.  Ferguson,  of  Rensselaer  County,  read  a 
paper  on 

THE    USB   OF  THE  ASPIRATOR   IN   HYDROTHORAX. 

A  case  was  cited  in  which  after  several  aspirations  were 
performed  for  pleuritis,  empyema  set  in.  The  author 
has  had  three  such  cases.  He  now  abstains  from  aspira- 
tion unless  the  dyspnoea  is  extreme.  When  the  opera- 
tion is  performed  only  a  slight  amount  of  fluid  should  be 
abstracted.  Since  following  this  rule,  he  has  not  had  a 
case  of  empyema  in  practice.  The  innocuousness  of  the 
operation  is  assumed  by  most  text-books,  the  only  warn- 
ing being  to  stop  when  there  is  constriction  at  ep^as- 
trium.  By  suddenly  emptying  the  chest  of  fluid,  support 
is  taken  from  the  vessels,  which  results  in  increase  d 
blood  with  resulting  tendency  to  suppuration.  Eight 
ounces  is  the  greatest  quantity  that  should  be  taken  at 
one  time  in  pleurisy. 

Dr.  Thomas  F.  Rochester,  of  Erie  County,  next 
read  a  paper  entitled 

A  NEW  procedure  IN  PARACENTESIS  THORAaS. 

The  histories  of  three  cases  of  empyema  were  given,  in 
all  of  which  there  was  great  difficulty  in  enlarging  the  in- 
cision sufficiently  to  hold  a  tube.  The  doctor  has  found 
that  by  inserting  his  finger  into  the  incision  and  thus  en- 
larging the  opening,  all  such  difficulty  is  overcome. 

Dr.  Austin  Flint  did  not  believe  that  the  aspirator 
caused  as  much  damage  as  claimed  by  Dr.  Ferguson, 
although  doubtless  it  sometimes  did  harm. 

Dr.  Moore  thought  that  all  surgical  instruments 
occasionally  did  harm.  In  empyema  the  best  practice  is 
to  draw  off  a  little  pus  each  week  by  the  aspirator.  Ib 
abscesses,  the  walls  of  which  cannot  contract,  all  pus 
should  not  be  drawn  out  at  once. 

Dr.  Rochester  thought  that  from  eight  to  tea  QVPC^ 


Very  Important  Announcement 


To  THE 

MEDICAL    PROFESSION 


OF  THE 


United  States  and  Canada 


1884 

WILLIAM   WOOD   &   COMPANY 

PUBLISHERS 

N  Ew  York 


1 


TO  BE   PUBLISHED  SOON. 


II  yiESSRS.  WILLIAM  WOOD  &  COMPANY  beg  leave  to  announce  to  the 
Medical  Profession  of  the  United  States  and  Canada  that  they  have  for 
several  years  past  been  organizing  and  arranging  for  the  preparation  of  a  work 
differing  from  all  others  heretofore  published  in  this  country,  and  calculated,  as 
they  believe,  from  its  character  and  the  high  reputation  of  its  very  large  staff  of 
learned  contributors,  to  be  the  most  practically  and  generally  useful  work  to  all 
classes  of  the  Medical  Profession  of  any  hitherto  presented  to  their  notice. 
This  valuable  work  will  be  entitled,  a 

REFERENCE    HANDBOOK 


'  Medical  Sciences. 

It  is  designed  that  this  superb  work  shall  cover  so  wide  a  field,  and 
embrace  such  a  great  variety  of  topics,  as  to  make  it  of  the  greatest  practical 
utility,  not  only  to  general  practitioners,  but  also  to  those  who  are  interested 
more  particularly  in  special  departments  of  medical  knowledge. 

This  work  will  consist  of  a  collection  of  concisely  written  essays  on 

ALL  THE  IMPORTANT  TOPICS  BELONGING  TO  THE 
BROAD  DOMAIN  OF  MEDICINE. 

Its  subject  matter  will  be  alphabetically  arranged,  thus  admitting  of  instant 
and  ready  reference,  with  no  loss  of  time  in  reading  over  page  after  page  to  find 
the  precise  item  desired.  Kindred  topics  will  be  connected  by  the  aid  of 
numerous  cross  references  in  such  a  manner  that  a  person  in  search  of  information 


can  scarcely  fail  to  find  everything  he  desires,  and  all  the  material  which  the  work 
contains  in  relation  to  the  subject  under  consideration. 

It  is  aimed  to  treat  the  topics  in  such  a  thorough  manner  that  the  reader 
will  rarely,  if  ever,  find  it  necessary  to  consult  larger  special  treatises  or  mono- 
graphs for  the  information  of  which  he  may  stand  in  need. 

The  number  of  those  physicians  who  take  an  interest  in  the  more  purely 
scientific  branches  of  medical  knowledge  is  already  quite  large,  and  will  undoubtedly 
increase  as  time  goes  on.  It  has,  therefore,  been  thought  advisable  to  devote 
considerable  space  to  the  more  important  topics  belonging  to  the  domain  of 

ANATOMY,     EMBRYOLOGY,     HISTOLOGY,     PHYSIOLOGY,     PHYSIO- 
LOGICAL AND  PATHOLOGICAL  CHEMISTRY,  PATHOLOGICAL 
ANATOMY,  CLIMATOLOGY,  AND  MEDICAL   BOTANY. 

All   these    topics,    as   well   as   those    belonging   to   the    more    directly   practical 

branches  of  medical  knowledge,  such  as 
\ 
GENERAL      PATHOLOGY      AND      THERAPEUTICS,      SURGERY, 

GYNECOLOGY,    NEUROLOGY,    OTOLOGY,    OPHTHAL- 
MOLOGY,   OBSTETRICS,    &c.,    &c.,    &c., 

have  been  asfigned  to  writers  who  are  experts  in  their  respective  departments. 

Wood-cut  illustrations  of  the  best  character  will  be  introduced  wherever 
the  authors  themselves  think  that  they  will  serve  to  elucidate  the  text.  Special 
pains  have  been  taken  to  secure  as  large  a  proportion  of  original  cuts  as  possible, 
and  no  expense  has  been  spared  in  this  or  in  any  other  branch  of  the  work 
to  secure  the  highest  order  of  excellence. 

In  a  work  of  such  magnitude  and  importance,  the  question  of  the  size  of 
the  page,  the  character  of  the  type,  and  the  number  of  volumes  could  be  decided 
only  after  the  most  careful  consideration  of  the  following  points  : 

A  work  intended  to  be  useful  to  the  great  mass  of  the  Medical  Profession 
must  furnish  FAIRLY  EXHAUSTIVE  INFORMATION  ON  ALL  THE  SUBJECTS  OF  WHICH 
IT  TREATS,  and  to  accomplish  this  within  the  compass  of  two,  three,  or  even  four 
volumes    of  a    si^e    convenient    for    handlin^r    would    scarcely    be    possible.     On    the 


other  hand,  it  is  more   than   likely  that  the  Profession  ytrould  not  receive  favorably 
a   work — no   matter  how    exhaustive    might    be   the   information   contained   in    its 
pages — which  comprised  a  dozen  or  more  volumes. 
The 

REFERENCE  HANDBOOK 


Medical  Sciences 

will,  therefore,  be  limited  to  a  series  of  from 

EIGHT    SPLENDID    IMPERIAL    OCTAVO    VOLUMES, 
THOROUGHLY    WELL    ILLUSTRATED, 

of  about  Eight  Hundred  Pages  each. 

The  pages  are  to  be  of  large  size,  in  double  columns,  and  the  type  as 
small  as  can  be  read  comfortably  by  a  person  of  ordinarily  good  eyesight. 

It  will  be  seen  that  the  volumes  admit  of  the  introduction  of  an  enormous 
amount  of  reading  matter  (equal  to  the  contents  of  twenty  of  the  usual  size  of 
octavo  volumes),  which  will  be  of  so  practical  a  nature  that  the  entire  work  will 
be  literally  a  handbook  for  the  daily,  constant  reference  of  the  Profession, — a  book 
which  no  physician,  whose  time  is  worth  anything  at  all,  can  afford  to  be  without. 

Large  treatises  on  the  Practice  of  Medicine  and  Surgery,  and  on  other 
branches  of  medical  knowledge  have  their  appropriate  and  necessary  place, — 
for  long,  deliberate  and  patient  study, — but  this  REFERENCE  HANDBOOK 
is  designed  to  furnish  not  only  THOROUGH  AND  EXHAUSTIVE  IN- 
FORMATION,  but  to  be  a  constant  daily  companion  and  ready  reference  on 

ALL   BRANCHES  OF  MEDICINE  AND  THE  COLLATERAL 

SCIENCES. 

A  large  part  of  the  material  contained  in  this  HANDBOOK  is  original  work, 
and,  upon  some  subjects,  the  information  now  to  be  presented  has  heretofore  been 
inaccessible,  by  reason  of  its  being  scattered  through  governmental  and  other 
manuscript  records  and  archives. 


1 


The  expense  incurred  in  the  preparation  of  the  Handbook  of  Reference  is, 
from  this  and  other  causes,  very  large,  and  could  only  be  warranted  by  the 
probability  of  an  extensive  sale  of  the  work.  The  publishers  feel  confident,  from 
the  generous  support  heretofore  accorded  their  publications,  that  for  this  great 
work,  exceeding  in  value,  as  they  consider,  anything  in  medicine  as  yet  pub- 
lished or  announced,  a  sale  commensurate  with  its  importance  may  confidently 
be  expected. 

PRICES   AT   WHICH   THIS   WORK   WILL   BE   SOLD. 

In  extra  English  muslin  binding,  .  -  -  -  Per  volume,  $6.00 

In  fine  leather,  raised  bands,  -  -  -  -  -  "  7.00 

In  extra  Turkey  Morocco,   English  doth  sides.  -  -  "  8.00 

These  volumes  will  all  be  sewed  by  the  new  patented   machine  sewing — giving 
great  elasticity,  remarkable  strength  and  fine  finish. 

t»-SOLD   ONLY  BY  SUBSCRIPTION.^'mik 


It  is  with  pardonable  pride  that  the  Editor  and  Publishers  present  herewith 
the  list  of  eminent  contributors  who  have  already  accepted  the  invitation  to  write 
on  certain  specified  topics.  It  is  believed  no  such  number  of  prominent  writers 
and  teachers  have  ever  before  been  associated  together  in  the  preparation  of  a 
work  specially  designed  for  the  Medical  Profession. 

As  comparatively  few  subjects  still  remain  unprovided  for,  the  list  of  names 
here  presented  will  not  be  materially  extended,  though  some  will  be  added  from 
time  to  time  in  the  progress  of  the  work. 

EDITOR  OP  THE  HANDBOOK, 

Albert  H.  Buck,  M.D. 


CONTRIBUTORS. 


APPLIED     ANATOMY. 


FRANK   BAKER,  M.D., 

WASHINGTON,    D.C., 

Prof,   of   Anatomy,    Medical    Department   of   Georgetown 

University. 

SIMON    H.  GAGE,  B.S., 

ITHACA,    N.  v., 


logy 


I'echnology,  Cornell  University. 

R.   L.   MAC   DONNELL,  M.D., 

MONTREAL,   CANADA, 

Demonstrctor  of  Anatomy  and   Lecturer  on   Hygiene,  McGill 

University. 


FRANCIS   J.   SHEPHERD,  M.D., 

MONTREAL,   CANADA, 

Prof,  of  Anatomy,  McGill  University. 
BENJAMIN   F.   WESTBROOK,  M.U., 

BROOKLYN,   N.  Y., 

Lecturer  on  Anatomy,  Long  Island  College  Hospital  Medical 

School  •   Phystcian-in-Chief  to  the   Department   for 

Diseases  of  the  Chest,  St.  Mary's  Hospital. 

BURT   G.   WILDER,  M.D.. 

ITHACA,   N.  v.. 

Prof,  of  Physiology,   Comparative   Anatomy,  and   Zoology   in 
Cornell  University. 


MICROSCOPICAL    TECHNOLOGY. 


GEORGE  C.   FREEBORN.  M.D., 

NEW   YOKK,   N.  Y., 

Aural  Surgeon,  N.  Y.  Eye  and  Ear  Infirmary. 


BIOLOGY,    MORPHOLOGY,   AND    EXPERIMENTAL    PHYSIOLOGY. 


E.  A.  BIRGE,  Ph.D., 

MADISON,  WISCONSIN, 

Prof,  of  Zoology,  University  of  Wisconsin. 
L.   BREMER,  M.D., 

ST.  LOUIS,  MO. 

W.  K.    BROOKS,  PH.D., 

BALTIMORE,  MD., 

Aswxiate    Prof,   of   Morphology,  Johns    Hopkins  University; 
Director  of  the  Chesapeake  Zoological  Laboratory. 

LESTER  CURTIS,  M.D., 

CHICAGO,   ILL., 

Prof,  of  Histology,  Chicago  Medical  College ;  Lecturer  on  Dis- 
eases of  the  Throat  and  Chest,  South  Side  Dispensary  ; 
Visiting  Physician  to  Mercy  Hospiul. 

H.  GRADLE.  M.D., 

CHICAGO,   ILL., 

Prof,  of  Physiology,  Chicago  Medical  College. 

LEWIS   L.  McARTHUR,  M.D., 

CHICAGO,   ILL. 

CHARLES   SEDGWICK   MINOT,  M.D., 

BOSTON,  MASS., 

Instructor  in  Histology  and  Lecturer  on  Embryology,  Harvard 
University. 

HENRY   F.  OSBORN,  Sc.D., 

PRINCBTON,   N.  J., 

Prof,  of  Comparative  Anatomy,  Princeton  University. 


ISAAC   OTT,  M.D., 

BAfTON,    PA. 

T.   MITCHELL   PRUDDEN,  M.D., 

NBW  YORK,  N.  V., 

Lecturer  on  Normal  Histology,  Yale  College ;  Director  of  the 

Physiological   and    Pathological    Laboratory   of   the 

Alumni  Association,  College  of  Physicians 

and  Surgeons,  New  York  City. 

WILLIAM   B.  SCOTT,  Ph.D.  (Heidelberg). 

PRINCBTON,   N.  J., 

Prof,  of  Geology,  Princeton  University. 
WILLIAM   T.   SEDGWICK,  PH.D., 

BOSTON,   MASS., 

Assistant  Prof,  of  Biology,  Massachusetts  Institute  of 
Technology. 

EDWARD   O.  SHAKESPEARE,  M.D., 

PHILADELPHIA,  PA., 

Ophthalmic  Surgeon  and  Pathologist  to  the  Philadelphia 
Hospital. 

JAMES   K.  THACHER,  M.D  , 

NEW   HAVEN,   CONN., 

Prof,  of  Physiology,  Yale  College. 

W.   G.  THOMPSON,  M  D., 

NEW  YORK,  N.  Y., 

Assistant   Physician  to  the  New  York  Hospital,  Out-Patient 

Department;  Physician  to  Roosevelt  Hospital, 

Out-Patient  Department. 


PHYSIOLOGICAL  AND  PATHOLOGICAL  CHEMISTRY;    TOXICOLOGY. 


RUSSELL  H.  CHITTENDEN,  Ph.D., 

NEW  HAVEN,  CONN., 

Prof,  of  Physiological  Chemistry,  Yale  College. 


WILLIAM    B.  HILLS,  M.D., 

BOSTON,  MASS., 

Assistant  Prof,  of  Chemistry,  Harvard  University. 


T.   WESLEY   MILLS.  M.D., 

MONTREAL,   CANADA, 

Demonstrator  of  Practical   Physiology   and  Histology,  McGill  University. 


PATHOLOGICAL    ANATOMY. 


W.  T.  COUNCILMAN,  M.D., 

BALTIMORE,   MD., 

Associate  Prof,  of  Pathological  Anatomy,  Johns  Hopkins 
University,  Baltimore. 

WILLIAM    W.  GANNETT,  M.D., 

BOSTON,    MASS., 

Assistant  in  Pathological  Anatomy,  Harvard  University. 


J.   WEST   ROOSEVELT,  M.D., 

NEW  YORK,   N.  Y., 

Assistant  Pathologist  and  Curator,  Roosevelt  Hospital 


E.  C.  WENDT,  M.D., 

NEW  YORK,  N.  Y. 


HYGIENE    AND    PUBLIC    HEALTH. 


SAMUEL   W.  ABBOTT,  M.D., 

BOSTON,   MASS., 

Health  Officer  of  the  Massachusetts  Sute  Board  of  Health, 
Lunacy  and  Charity. 

PETER  H.   BRYCE,  M.B.  (Toronto  University), 

TORONTO,   CANADA, 

Prof,  of  Chemistry,   Ontario  Agricultural  College;    Secretary 
of  the  Provincial  Board  of  Health. 

WILLIAM   S.   CHEESMAN,  Jr.,  M.D., 

Al-BIRN,    N.  Y. 

EDWARD   COWLES,  M.D., 

SOMBRVILLB,   MASS., 

Superintendent  of  the  McLean   Asylum ;  late  Superintendent 
r>f  the  Boston  City  Hospital. 


GEORGE   W.  LEONARD,  M.D., 

NEW   YORK,  N.  V., 

Formerly  House  Surgeon,  New  York  Hospital. 
WILLIAM   RIPLEY   NICHOLS,  S.B., 

UOSTO.V,   MASS., 

Prof,   of  General   Chemistry,   Massachusetts  Institute  of 
Technology. 

WILLIAM   OLDRIGHT,  M.D.  (Toronto  Univ.), 

TORONTO,   CANADA, 

Lecturer  on   Sanitary  Science,   Toronto  School  of  Medicine; 
Chairman,  Provincial  Board  of  Health. 

FREDERICK   N.   OWEN,  E.M., 

NKW    YORK,   N.  Y., 

Civil  and  Sanitary  Engineer. 


^f?:^' ^'  r  * .  •     '  ' 


MILITARY    AND    NAVAL     MEDICINE,    HYGIENE    AND 
SANITARY    SCIENCE. 


ALBERT   L    GIHON,  M.D., 

WASHINGTON^   D.C., 

Medical   Director,   United  States  Navy;   President  of  the 
American  Public  Health  Association. 

CHARLES   R.  GREENLEAF,  M.D., 

coli;mbus  barkacks,  01110, 

Surgeon,  United  States  Army. 


CHARLES  SMART,  M.D., 

WASHINGTON,   D.C., 

Surgeon,  United  States  Array. 
JOSEPH    R.  SMITH,  M.D., 

SAN   ANTONIO,  TBXAS, 

Medical  Director,  United  States  Army. 


ALFRED   A.  WOODHULL,  M.D., 

David's  island,  new  vork  harbor. 

Surgeon,  United  States  Army. 


CLIMATOLOGY,     HEALTH     RESORTS    AND     MINERAL    SPRINGS. 


HUNTINGTON   RICHARDS,  M.D., 

NEW    YORK,   N.  v., 

Assistant  Aural  Surgeon,  N.  Y.  Eye  and  Ear  Infirmary. 


BEAUMONT  SMALL,  M.IX, 

OTTAWA,  CANADA. 


MEDICAL    JURISPRUDENCE. 


BENJAMIN   VAUGHAN   ABBOTT, 

NEW   VORK,   N.  v.. 

Author  of  "Abbott's  Law  Dictionary,"  and  various  Digests. 


WILUS   J.  ABBOT,  LL.B., 

CHICAGO,    11.1.. 


GENERAL     PATHOLOGY     AND     THERAPEUTICS.     AND 
PHYSICAL    DIAGNOSIS. 

M.D.. 


I.  EDMONDSON  ATKINSON 

BALTIMORR,   MD., 

Prof,  of  Pathology  and   Clinical    Professor   of    Dermatology, 
University  of  Maryland. 

DALLAS   BACHE,  M.D., 

FORT   ADAMS,  R.  I., 

Surgeon,  United  States  Army. 
G.  BAUMGARTEN,  M.D., 

ST.   LOUIS,   MO., 

Prof,  of  Physiology,  St.  Louis  Medical  College. 
ALBERT  N.  BLODGETT,  M.D., 

BOSTON,   MASS., 

Prof,  of  Pathology  and  Therapeutics,  Boston  Dental  College. 
ISRAEL  T.  DANA,  M.D., 

PORTLAND,   MB., 

Attending  Physician,  Maine  General  Hospital,  Portland. 
N.   S.   DAVIS,  M.D., 

CHICAGO,    ILL., 

ProC  of  Principles  and  Practice  of  Medicine  and  of  Clinical  Medi- 
cine, Chicago  Medical  College ;  Physician  to 
the  Mercy  Hospital. 

HAROLD  C.  ERNST,  M.D., 

BOSTON,   MASS., 

Assistant  Pathologist  to  the  Boston  City  HospitaL 
R.  H.  FITZ,  M.D., 

BOSTON,    MASS., 

Shattuck  Professor  of  Pathological  Anatomy,  Harvard  University. 
WILLIAM    H.   FLINT,  M.D., 

NKW  YORK,    N.   Y., 

Physician  to    the    Roosevelt  Hospiul,   Out- Patient  Department; 

Assistant  to  the  Chair  of  Principles  and  Practice  of 

Mediane,  Belle vue  Hospiul  Medical  College. 

EUGENE   FOSTER,  M.D., 

AUGUSTA,    GA., 

President  of  the  Board  of  Hodth  of  Augusta. 
JAMES   M.  FRENCH,  M.D., 

CINCINNATI,   OHIO, 

Assistant  Demonstrator  of  Pathology  and  In^^tructor  in   Physical 
Diagnosis,  Medical  College  of  Ohio,  Cincinnati 


DOUGLAS   GRAHAM,  M.D., 

BOSTON,   MASS. 

CHARLES  E.   HACKLEY,  MD,, 

NBW  VORK,    N.    v.. 

Attending  Physician,  New  Vork  Hospital. 
HENRY   N.   HEINEMAN,  M.D., 

Ni£W   YUKK,   N.  Y., 

Attending  Physician,  Mount  Sinai  Hospital :  Surgeon  to  the  N.  Y. 

Hospital,  Out-Patient  Depairtmeni,  Section  of 

Diseases  of  Children. 

FREDERICK   P.   HENRY,  M.D., 

PHILADBLPHIA,  PA., 

Prof,  of  PatholcNnr  and   Microscopy,  Philadelphia  Polyclinic  and 
College  for  Graduates  in  Medicine ;  Physician  to  the  Hos- 
pital of  the  Protestant  Episcopal  Church. 

MORRIS   L.   KING,  M.D., 

NKW  YORK,    N.   Y., 

Late  House  Surgeon,  Roosevelt  HospitaL 
ALFRED   L.  LOOMIS,  M.D., 

NSW  YORK,   N.   Y., 

Pro!  of  Pathology  and  Practice  of  Medicine,  University  Medical 
College,  New  York :  Physidan  to  Bellevue  HospiuL 

WALTER   MENDELSON,  M.D., 

NKW   YORK,   N.   Y., 

Late  House  Physician,  New  York  Hospital. 
WILLIAM   OSLER,   M.D., 

MONTREAL,  CANADA, 

Prot  of  the  Institutes  of  Medicine,  McGill  University. 
GEORGE   ROSS,  M.D  , 

MO.VTKSAL,   CANADA, 

Prof,  of  Qinical  Medicine,  McGill  University;  Physician,  Montreal 
General  Hospital. 

THOMAS   E.  SATTERTHWAITE,  M.D., 

NKW  YORK,   N.    Y., 

Prof,  of  Pathology  and  General  Medicine,  New  York  Post-Oail- 
uate  Medical  School ;  Pathologist  to  the  Presbyterian  Hospital. 

EDWARD   W.  SCHAUKFLER,  M.D., 

KANSAS  CITY,   MO. 


; 


General  Pathology  and  Therapeutics,  and  Physical  Diagnosis — ObnUnued, 


FREDERICK  C.  SHATTUCK,  M.D., 

BOSTON,  MASS., 

CUnkal  Instructor  in  Aufcultation  and  Percussion,  Hanrard  Med- 
ical College:    Physician  to  Out-Patients, 
Mass.  G«neral  Hospital. 

GEORGE   B.  SHATTUCK,  M.D., 

BOSTON,  MASS., 

Visiting  Physician,  Boston  City  Hospital. 
GEORGE   M.  STERNBERG,  M.D., 

FORT  MASON,   CALIVOKNIA, 

Surgeon*  United  States  Army. 
WILLIAM    H,   THOMSON,  M.D., 

NBW  YOKK,  N.  Y., 

ProC  Materia  Medica  and  Therapeutics  and  Diseases  of  the  Ner- 
vous System,  Medical  Department  of  the  University  of 
the  Gty  of  New  York ;  Visiting  Physician  to 
fidlevue  and  Roosevelt  Hospitals. 


SAMUEL  B.  WARD,  M.D., 

ALBAMY,  N.  Y.* 

Prof,  of  Pathokwv,  Practice,  Clinical  Medicine  and  Hygieae, 

Albany  Medical  College, ;  Attending  Surgeon, 

Albany  HospitaL 

LEONARD   WEBER,  M.D., 

NBW  YORK,   N.  Y. 

WARREN   WEBSTER,  M.D., 

FORT   PRBBUB,   MAINS, 

Surgeon,  United  States  Army. 
JAMES   T.  WHITTAKER,  M.D., 

CINCINNATI,  OHIO, 

Prof,  of  Physiology,  Medical  College  of  Ohio,  Cincinnati. 
GEORGE   WILKINS,  M.D., 

MONTRJEAL,   CANADA, 

Prof,  of  Medical  Jurisprudence,  McGill  University. 


MATERIA  MEDICA,  MEDICAL  BOTANY,  AND  PHARMACOLOGY. 


W.  P.  BOLLES,  M.D., 

BOSTON,  MASS., 

Prof,  of  Materia  Medica  and  Botany,  Massachusetts  College 

of  Pharmacy  ;  Instructor  in  Materia  Medica, 

Harvard  University. 

EDWARD  CURTIS,  M.D., 

NEW  YOSK.  M.  Y., 

Prof,  of  Materia  Medica  and  Therapeutics,  College  of  Phy- 
sicians and  Surgeons,  Mew  York. 


F.  PEYRE   PORCHER,  M.D., 

CHARLESTON,   S.  C, 

Prof,  of    Materia  Medica  and    Therapeutics,  in   the  Medical 
College  of  the  State  of  South  Carolina :  One  of  the  Phy- 
sicians to  the  City  Hospital,  Charleston. 

CHARLES   RICE,  Ph.D., 

NEW  YOKK,  N.  Y., 

Chairman  of  the  Committee  of  Revision  and  Publication  of  the 
Pharmacopoeia  of  the  United  States  of  America  (1880-1890). 


JAMES  STEWART,  M.D., 

MONTREAL,   CANADA, 

Prof,  of  Materia  Medica  and  Therapeutics. 


SURGICAL    PATHOLOGY    AND    GENERAL    SURGERY. 


EDMUND   ANDREWS,  M.D., 

CHICAGO,   ILL., 

Prof,   of  Clinical    Surgery  in   the  Chicago  Medical    College ; 
Surgeon  to  Mercy  Hospital,  Chicaga 

CHARLES  S.  BRIGGS,  M.D., 

NASHVILLE,  TBNM., 

Prof,  of  Surgical  Anatomy  and  Operative  Surgery  in  the  Medical 

Department  of  the  University  of  Nashvule  and 

Vanderbilt  University. 

JOSEPH    D.   BRYANT,  M.D., 

NEW  YORK,   N.  Y., 

Prof,  of  Anatomy  and  Associate  Pro£    of  Orthopedic    Surgery, 
Bellevue  Hospiul  Medical  College,  New  York. 

A.  T.  CABOT,  M.D., 

BOSTON,   MASS., 

Surgeon  to  Out-Patientii,  Massachusetts  General  Hospiul,  Boston. 
GEORGE   W.  GAY,  M.D., 

BOSTON,   MASS., 

Surgeon  to  the  Boston  City  HospitaL 
WILLIAM    H.  HINGSTON,  M.D., 

MONTXKAL,   CANADA. 

JOSEPH    W.   HOWE,  M.D., 

NEW  YORK,  N.  Y., 

Visiting  Surgeon  to  the  Charity  and  St.  Vincent*s  Hospitals. 
CHARLES   B.   KELSEY,  M.D., 

MHW  YORK,  N.  Y., 

Surgeon  to  St.  PanPs  Infirmary  for  Diseases  of  the  Rectum. 

E.  M.  MOORE,  M.D., 

ROCKESTEB,  N.  Y., 

Attending;  Surgeon,  St.  Mary^s  Hospital,  Rochester,  N.  Y.;   for- 
merly Prof,  of  Surgery,  University  of  BufiBsdo,  N.  Y. 

H.  H.   MUDD,  M.D., 

5T.  LOUIS,  MO., 

Prot  of  Anatomy  and  Clinical'  Sutigery,  St  Louis  Medical  College. 
ALFRED   NORTH,  M.D., 

WATSRBURY,  COttS. 

ROSWELL  PARK,  M.D., 

BUFFALO,  N.  Y., 

.Prof,  of  the  Principles  and  Practice  of  Surgery,   University  of 
Buffido,  N.  Y. 


L.  S.  PILCHER,  M.  D., 

BEOOKLYir,  N.  Y., 

Adjunct  Professor  of  Anatomy,  Long   Island    College    Hospital 
Medical  School. 

ABNER   POST,  M.D., 

BOSTON,  MASS., 

Surgeon  to  Out-Patients,  Boston  City  Hospital. 
JOSEPH    RANSOHOFF,  M.D., 

CINCINNATI,  OHIO, 

Prof,  of  Descriptive  Anatomy  and  Qinical  Surgery,  Medical 

College  oi  Ohio ;  Sturgeon  to  the  Good  Samaritan 

Hospittu,  Cincinnati. 

THOMAS   G.   RODDICK,  M.D., 

MONTRSAi.,  Canada, 

ProL  of  Qinical  Surgery,  McGill  University;  Surgeon,  Montreal 

General  Hospital. 

N.  SENN,  M.D., 

MILWAUKEE,   WISCONSIN. 

LEWIS   A.  STIMSON,  M.D., 

NEW  YORK,  N.   Y., 

ProC  of  Physiobgy,  University  of  the  City  of  New  York  :  Vinting 
Surgeon,  Bellevue  and  Presbyterian  Hospiuls. 

L.  McLANE   TIFFANY,  M.D., 

BALTIMORE,  MD., 

ProC  of  Surgery,  University  of  Maryland. 
ALBERT   VAN    DERVEER,  M.D., 

ALBANY,  N.  Y., 

Prof,  of  the  Principles  and  Practice  of  Surgery  and  Clinical  Surgery, 
Albany  Medical  College  :  Attending  Siugeon,  Albany  Hospital 

WILLIAM   L.   WARD  WELL,  M.D., 

NEW  YORK,    N.    Y., 

Surgeon,  Eastern  Dispensary ;  Assistant  Surgeon,  New  York 
Polyclinic 

J.  COLLINS   WARREN,  M.D., 

BOSTON,  MASS., 

Assistant  Prof,  in  Surgery,  Harvard  University:  Surgeon  to 
Mass.  General  Hospital. 

LEROY   M.  YALE,  M.D., 

NEW  YOKK,  N.   Y., 

Visiting  Surgeon,  Presbyterian  Hospital ;  Lecturer  Adiunct  00 
Diseases  of  Children,  Bellevue  Hospital  Medical  College. 


ORTHOPEDIC    SURGERY. 


EDWARD    H.   BRADFORD,  M.D., 

BOSTON,   MASS., 

Assistant  in  Clinical  Surgery,  Harvard  University :  Surgeon  to  th? 
Children's  Hospital,  Boston. 

V.  p.  GIBNEY,  M.D., 

NKW  YORK,    N.   V., 

Prof,  of  Orthopedic  Surgery,  New  York  Polyclinic  ;  Assistant 
Surseon.  Hospital  of  the  New  York  Society  for  the 
Relief  of  the  Ruptured  and  Crippled. 

CHARLES  T.    POORE,  M.D.. 

NKW  YORK,  N.  Y., 

Surgeon  to  St  Mary*s  Free  Hospital  for  Children. 


A.  SYDNEY  ROBERTS,  M.D., 

PHILADKLFHIA,  PA., 

Visiting  Surgeon  to  the  Philadelphia  Hospital  and  the  Orthopedic 
Dispensary  of  the  University  Hospital :  Instructor  in  Ortho- 
pedic Surgery  in  the  University  of  Pennsylvania. 

NEWTON  M.  SHAFFER,  M.D., 

NKW  YORK,  N.  v., 

Clinkail  Lecturer  on  Orthopedic  Surgery,  University  of  the  City  of 

New  York :  Attending  Surgeon-m- Chare e  of  the  New 

York  Orthopedic  Dispensary  and  Hospital. 

THOMAS  L.  STEDMAN.  M.D., 

NKW  YORK,  N.  Y., 

Assistant  Surgeon,  New  York  Orthopedic  Dispensary  and  Hospital. 


OBSTETRICS    AND    GYNAECOLOGY. 


F.  E.   l^ECKWITH,  M.D., 

NEW   HAVKN,  CONN., 

Prof,  of  Obstetrics  and  the  Diseases  of  Women  and  Children,  Yale 
College. 

J.  H.   EMERSON,  M.D., 

NBW  YORK,  N.  Y. 

JAMES   H.  ETHERIDGE,  M.D., 

CHICAGO,  ILL.. 

Prof,  of  Materia  Medica  and  Medical  Jurisprudence,  Rush  Medi- 
cal College. 

FRANK   P.   FOSTER,  M.D., 

NKW  YORK,  N.  Y., 

Assistant  Burgeon,  Woman's  Hospital  in  the  State  of  New  York. 

WILLIAM   GARDNER,   M.D., 

MONTREAL,  CANADA, 

Prof,  of  Gynaecology,  McGiU  University. 
MATTHEW   D.   MANN,  M.D., 

BUFFALO,  N.  Y., 

Prof,  of  Obstetrics  and  Gynaecology,  University  of  Buffalo,  N.  Y. 


EDWARD   L.   PARTRIDGE,  M.D., 

NBW  YORK,  N.  Y., 

Prof,  of  Obstetrics,  New  York  Post-Graduate  Medical  School  and 

Hospital ;  Physician  to  the  Nursery  and  Child's  Hospital ; 

Gynaecologist  to  the  Out-Pattent  Department  o« 

the  New  York  HospiuL 

THEOPHILUS   PARVIN,  M.D., 

PHILADBLPHIA,  PA., 

Prof,  of  Obstetrics  and  Diseases  of  Women  and  Children,  Jeffer* 
sou  Medical  College. 

J.  C    REEVE,  M.D., 

DAYTON,   OHIO, 

Formerly  Prof,  of  Materia  Medica  and  Therapetitics,  Medical 

College  of  Ohio ;  Chief  of  Staff  of  St.  Elizabeth's  Hospital, 

Dayton. 

GEORGE  M.  TUTTLE,  M.D., 

NEW  YORK,  N.  Y., 

Asustant  to  the  Chair  of  Obstetrics,  College  of  Physicians  and 

Surgeons,  New  York  ;  Gynaecologist  to  Roosevelt 

Hospital,  Out-Patient  Department. 

C.  F.   WITHINGTON,  M.D., 

BOSTON,  MASS. 


W.  GILL  WYUE,  M.D., 

NBW  YORK,  N.  Y., 

Prof,  of  Gynaecology,  New  York  Polyclinic ;  Gynaecologist  to  Bellevue  Hospital ;  Surgeon  to  St.  Elisabeth's  Hospital. 


DISEASES    OF    CHILDREN. 


W.  J.  CONKLIN,  M.D., 

DAYTON,  OHIO, 

Prof,  of  Diseases  of  Children,  Starling  Medical  College. 


ELBRIDGE  G.  CUTLER,  M.D., 

BOSTON,  MASS., 

Physician  to  Out-PatienU,  Mass.  General  Hospital ;  Physician 
to  Carney  Hospital. 


WILLIAM  P.  NORTHRUP,  M.D., 

NSW  YORK,  N.  Y., 

Pathologist  to  the  New  York  Foundling  Asylum. 


DISEASES    OF    THE    MIND    AND    NERVOUS    SYSTEM. 


HENRY  W.   BERG,  M.D., 

NSW  YORK,  N.  Y., 

Assistant  Surgeon,  N.  Y.  Orthopedic  Dispensary  and  Hospital. 
CHARLES  L.   DANA,  M.D., 

NBW  YORK,  N.  Y., 

?rof .  of  Diseases  of  the  Mind  and  Nervous  System,  and  of  Medi- 
cal Electricity,  New  York  Post-Graduate  Medical  School 
and  Hospital ;  Physician  to  the  Northwestern 
Dispensary,  Nervous  Department. 

W.  B.  GOLDSMITH,  M.D., 

DANVKRS,  MASS., 

Superintendent  of  the  Danvers  Lunatic  Hospital. 

ALLAN  McLANE  HAMILTON,  M.D., 

NEW  YORK,  N.  Y., 

Prof,  of  Diseases  of  the  Mind  and  Nervous  System,  New  York 
Polyclinic. 


THEODORE  H.  KELLOGG,  M.D.,' 

NBW  YORK,  N.  Y., 

Late    AssisUnt    Resident  Physician,   New  York  City   Lunatic 

Asylum,  Blackwell's   Island,  and   Physician-in-Charge  of 

New  York  City  Asylum  for  the  Insane,  Ward's  Island. 

JAMES  J.   PUTNAM,  M.D., 

BOS  ION,    MASS., 

Physician  to  Out- Patients,  Department  of  Diseases  of  the  Nervous 

System,  Massachusetts  General  Hospital ;  Instructor  in 

Diseases  of  the  Nervous  System,  Harvard  Medical 

College. 

L.  PUTZEL,  M.D., 

NEW  YORK,  N.  Y., 

Visiting  Physician  to  Randall's  Island  Hospital. 
M.  ALLEN  STARR,  M.D., 

NKW  YORK,  N.  Y., 

Late  House  Physician,  Bellevue  Hospital ;  Attending  Physician, 


New  York  Dispensary. 


GEORGE  L.   WALTON,  M.D., 


BOSTON,  MASS., 


Assistant  in  Out-Patient  Department  for  Dii 


of  the  Nervous  System,  Massachusetts  General  Hospital. 


DISEASES    OF    THE    SKIN. 


LUCIUS  D.  BULKLEY,  M.D., 

NBW  YORK,  N.  Y., 


HENRY  W.  STELWAGON,  M.D., 

PHILADELPHIA,  PA., 

Phrtictan  to  the  Philadelphia  Dispensary  for   Skin  Diseases 

Chief  of  the  Skin  Dispensary  of  the  Hospital,  and  Instructor 

in  Dermatology,  University  of  Pennsylvania. 

ARTHUR  VAN  HARLINGEN,  M.D^ 

PHILADSLPHIA,  PA., 

Prof,  of  Diseases  of  the  Skin  in  the  Philadelphia  Polyclinic  and 

College  for  Graduates  in  Medicine :  Consulting  Physician 

to  the  Dispensary  for  Sldn  Diseases. 

JAMES  C.  WHITE,  M.D., 

BOSTON,  MASS., 

Prof,  of  Dermatology,  Harvard  University. 
HENRY  WILE,  M.D., 

PHILADELPHIA,  PA., 

Clinical  AssisUnt  in  Dermatologv  in  the  University  of  Pennsylvania ;  Assistant  ?hyaician  to  the 
iladelphia  Dispensary  for  Skin  Dii 


Surgeon  to  the  New  York  Ho8i>ital,  Out-Patient  Department, 
Section  of  Skin  Diseases. 

JAMES  E.  GRAHAM,  M.D., 

TORONTO,  CANADA, 

Lecturer  on  Diseases  of  the  Integumentary  System,  Toronto 
School  of  Medicine. 

ROBERT  B.  MORISON,  M.D., 

BALTIMORB,  MD., 

Prof,  of  Dermatology  and  Syphilis,  Baltimore  Polyclinic  and 
Post- Graduate  Medical  School. 


Philadelphia  Dispensary  for  Skin  Diseases. 


LARYNGOLOGY    AND     DISEASES     OF    THE     NOSE    AND     THROAT. 


FRANCKE  H.  BOS  WORTH,  M.D., 

NEW  YORK,  N.  V., 

Prof,  of  Diseases  of  the  Throat,  Bellevue  Hospital  Medical  Col- 
lege ;  Physician-in-charge  of  the  Clinic  for  Diseases  of 
the  Throat  in  the  Out-Door  Department  of 
Bellevue  Hospital. 

D.  BRYSON  DELAVAN,  M.D., 

NBW  YORK,  N.  Y., 

Surgeon  to  Department  of  the  Throat,  Demilt  Dispensary. 


GEORGE  M.  LEFFERTS,  M.D., 

NKWYORK,  N.  Y., 

Prof,  of  Laryngology,  College  of  Physicians  and  Surgeons,  New 
York;  Throat  Surgeon,  N.  Y.  Eye  and  Ear  Infirmary. 

JOHN  N.  MACKENZIE,  M.D., 

BALTIMORB,  MD., 

Surgeon  to  the  Baltimore  Eye,  Ear  and  Throat  Charity  HospitaL 


OPHTHALMOLOGY. 


ADOLF  ALT,  M.D., 

ST.   LOUIS,  MO. 

CHARLES  S.  BULL,  M.D., 

NBW  YORK,  N.  Y.. 

Lecturer   mi    Ophthalmology  and  Otology,  Bellevue  Hospital 

Medical  College ;  Ophthalmic  Surgeon,  N.  Y.  Eye  and 

Ear  Infirmary. 

HASKET  DERBY,  M.D., 

BOSTON,  MASS., 

Ophthalmic  Surgeon,  Massachusetts  Chariuble  Eye  and  Ear 
Infirmary,  Boston. 

RICHARD  H.  DERBY,  M.D., 

l<OSTON,  MASS., 

Ophthalmic  Surgeon,  N.  Y.  Eye  and  Ear  Infirmary. 
EZRA  DYER,  M.D., 

NEWPORT,  R.  I. 


JOHN  GREEN,  M.D., 

ST.    LOUIS,  MO., 

Lecturer  on  Ophthalmology,  St.  Louis  Medical  College. 

B.  JOY  JEFFRIES,  M.D., 

BOSTON,  MASS.. 

Ophthalmic  Surgeon  to  the  Mass.  Charitable  Eye  and  Ear  Infir- 
mary, the  Carney  Hospital,  and  the  New  England  Hospital 
for  Women  and  Children. 

W.  OUVER  MOORE,  M.D., 

NBW  YORK,  N.  Y., 

Prof,  of  the  Diseases  of  the  Eye  and  Ear,  N.  Y.  Post-Graduate 

Medical  School ;  Assistant  Surgeon  to  the  New  York 

Eye  and  Ear  Infirmary. 

SAMUEL  THEOBALD,  M.D., 

BALTIMORB,  MD., 

Prof,  of  Diseases  of  the  Eye  and  Ear,  Baltimore  Polyclinic  and 
Post-Graduate  Medical  School;  Surgeon  to  the  Balti- 
more Eye,  Ear  and  Throat  Charity  Hospital. 


EDWARD  ALLEN  FAY, 


WASHINGTON,  D.  C, 

Editor  of  '*  American  Annals  for  the  Deaf  and  Dumb.' 


DEAF-MUTISM. 

I  E.  M.  GALLAUDET,  Ph.D.,  LL.D., 


WASHINGTON,  D.  C, 

President  of  National  Deaf-Mute  College,  Washington. 


CAROLINE  A.  YALE,  . 

NORTHAMPTON.   MASS., 

Associate  Principal  of  the  Clarke  Institution  for  Deaf-Mutes. 


OTOLOGY, 


GORHAM  BACON.  M.D., 

NBW  YOKK,  N.  Y., 

Aural  Surgeon  N.  Y.  Eye  and  Ear  Infirmary. 

CLARENCE  J.  BLAKE,  M.D., 

BOSTON.  MASS.^ 

Instructor  in  Otology  in  Harvard  University  ;  Aural  Surgeon, 
Mass.  Charitable  Eye  and  Ear  infirmary. 

ALBERT  H.  BUCK,  M.D., 

NBW  YORK,  N.  Y., 

Formerly  Instructor  in  Otology  in  the  College  of  Physicians  and 

Surgeons,  New  York,  and  Aural  Surgeon  to  the  New  York 

Eye  and  Ear  Infirmary. 

FRANK  BULLER,  M.D., 

MONTREAL,  CANADA, 

Prof,  of  Ophthalmology  and  Otology,  McGill  University. 

CHARLES  H.  BURNETT,  M.D., 

PHILAOBLPHIA,  PA., 

Prof,    of   Otology,    Philadelphia    Polyclinic    and    College    for 

Graduates  in  Medicine  ;  Aurist  to  the  Presbyterian 

HospitaL 


J.  ORNE  GREEN,  M.D., 

BOSTON,   MASS., 

Aural  Surgeon,  Boston   City  Hospital;  Clinical   Instructor  in 
Otology,  Harvard  University. 

D.  B.  ST.  JOHN  ROOSA,  M.D., 

NBW   YORK,   N,  Y., 

Prof,  of  Diseases  of  the  Eye  and  Ear,  New  York  Post-Graduate 

Medical  School ;  Surgeon  to  the  Manhattan    Eye 

and  Ear  Hospital. 

W.  W.  SEELY,  M.D., 

CINCINNATI.  OHIO, 

Prof,  of  Ophthalmology  and  Otology,  Medical  College  of  Ohio, 
Cincinnati. 

SAMUEL  SEXTON,  M.D., 

NBW  YORK,   N.  Y., 

Aural  Surgeon,  N.  Y.  Eye  and  Ear  Infirmary. 

H.  N.  SPENCER,  M.D., 

ST.  LOUIS,  MO., 

Prof,  of  Diseases  of  the  Ear,  St.  Louis  Post-Graduate  School 

of  Medicine,  Polyclinic  and  Hospital  Association  ;  Aural 

Surgeon  to  the  St.  Louis  Free  Hospital  for  Children. 


SUPPLEMENTARY  LIST  OF  CONTRIBUTORS. 

(The  foregoing  classified  list  was  prepared  early  in  the  autumn,  and  the  following  names  have  been 
added  since  that  date.) 


WILLIAM  R.  BIRDSALL,  M.D., 

NKW  YORK,  N.  Y., 

Assistant  Physician,  Department  for  Nervous  Diseases,  Man- 
hattan eye  and  Ear  Hospiui. 

EDWARD  B.  BRONSON,  M.D., 

NBW  YORK,  N.  Y., 

Prof,  of  Dermatology,  New  York  Polyclinic;  Dermatologist  to 
the  Northern  Dispensary. 


HOWARD   M.  BUCK, 

BOSTON,   MASS. 


M.D., 


WILLIAM  N.  BULLARD,  M.D., 

BOSTON,   MASS., 

Physician  to  Department  of  Nervous  Diseases,  Boston  Dis- 
pensary. 

DONALD  M.  CAMMANN,  M.D., 

NEW  YORK,  N.  Y., 

Instructor  in  Diseases  of  the   Chest,  New  York  Polyclinic; 
Visiting  Physician  to  the  Orphans*  Home  and  Asylum. 

WILLIAM  H.  FORD,  M.D., 

PHILADBLPHIA,   PA. 

GEORGE  B.  FOWLER,  M.D., 

NSW   YORK,  N.  y.. 

Prof,  of  Physiolojfical  Chemistry,  New  York  Polyclinic;  Physi- 
cian to  the  New  York  Infant  Asylum. 

WALTER  R.  GILLETTE,  M.D., 

NBW   YORK,  N.  Y., 

Prof,  of  Obstetrics,  New  York  Polyclinic;  Visiting  Physician 
to  Bellevue  and  St.  Francis  Hospiuls. 

GEORGE  S.  HUNTINGTON,  M.D., 

NEW   YORK,  N.  V., 

Member  of  the  Resident  Surgical  Staff,  Roosevelt  Hospital. 
HENRY  KOPLIK,  M.D., 

NSW  YORK,  N.  Y., 

Assistant  in  Normal  Histology,  Physiological  and  Pathological 

Laboratory  of  the  Alumni  Association  of  the  College 

of  Physicians  and  Surgeons. 


F.   HOWARD   LOMBARD,  M.D., 

BOSTON,   MAS.S., 

District  Physician,  Boston  Dispensary;  Late  Interne  at  the 
Sntbindungsatutalt  in  Dresden,  Germany. 

JULIAN  A.  MEAD,  M.D., 

WATBSTOWN,   MASS., 

Medical  Examiner  for  Middlesex  County,  MassachusetU. 
MIDDLETON  MICHEL,  M.D.. 

CHAKLSSTON,  S.  C, 

Prof,  of  Surgery  in  the  Medical  College  of  the  State  of  South 

Carolina;  one  of  the  Surgeons  to  the  City  Hospital, 

Charleston. 

WILLIAM  H.  MURRAY,  M.D., 

NBW   YORK,  N.  Y., 

Late  House  Surgeon,  New  York  Hospital  House  of  Relief; 
Attending  Physician,  New  York  and   Northern  Dis- 
pensaries. 

IRVING  C.  R08SE,  M.D., 

WASHINGTON,  D.  C. 

A.  N.  TALLEY.  M.D., 

COLUMBIA,  S.  C. 

CHARLES  WARE.  M.D.. 

NBW   YORK,  N.  Y., 


AsBisUnt  Gynecologist,  Out- Door  Department 
Hospiui. 


of  Roosevelt 


MOSES  C.  WHITE,  M.D., 

NBW    HAVBN,  CONN.. 

Prof,  of  Pathology,  Medical  Department  of  Yale  College. 
EDWARD   S.  WOOD,  M.D.,* 

BOSTON,  MASS., 

Prof,  of  Chemistry,  Harvard  Medical  School. 
JOHN  McG.  WOODBURY,  M.D., 

NBW   YORK,  N.  Y. 

SAMUEL  B.  WOODWARD,  M.D.. 

WORCBSTBR,   MASS. 


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November  22,  1884.] 


THE  MEDICAL  RECORD. 


575 


were  enough  to  take  out  at  one  time.  He  believes  in 
the  drainage  tube,  and  has  had  no  success  with  fistulous 
openings. 

Dr.  Feifield,  of  Boston,  has  used  his  finger  to  en- 
large the  opening  in  empyema  for  some  time. 

Dr.  Austin  Flint,  of  New  York,  read  a  paper  dn  the 

DIETETIC  treatment  OF  DYSPEPSIA. 

Some  authorities  give  the  term  dyspepsia  as  synonymous 
with  the  term  indigestion ;  but  he  maintained  that  the 
terni  dyspepsia  denotes  an  affection  distinct  from  indi- 
gestion. He  then  gave  the  local  or  stomach  and  general 
symptoms  of  the  affection.  The  appetite  may  be  im- 
paired, but  is  sometimes  increased.  The  mind  plays  an 
important  part  in  the  etiology  of  the  affection.  The  old 
method  of  treatment  was  to  strictly  regulate  the  diet, 
drink  very  little  or  no  fluids,  and  always  leave  the  table 
hungry.  Such  treatment  is  entirely  wrong.  Dyspepsia 
may  be  developed  by  the  attempt  to  regulate  the  diet  by 
rules  intended  to.  prevent  the  affection.  I  always  ask 
a  patient,  Do  you  regulate  your  diet  ?  and  he  always  an- 
swers in  the  affirmative.  I  have  never  known  a  dyspeptic 
to  get  well  who  attempted  to  regulate  his  diet.  Regulate 
by  the  appetite,  the  palate,  and  by  commqn  sense.  A 
patient  may  ask.  Am  I  not  to  be  guided  by  personal 
experience  and  avoid  such  articles  as  I  have  found  to 
disagree  with  me  ?  I  answer  that  personal  experience 
is  very  deceptive.  An  article  that  would  disagree  to-day 
would  agree  to-morrow.  Do  not  adopt  the  rules  of  eating 
only  twice  or  thrice  a  day.  Be  governed  by  the  appetite. 
Those  articles  are  most  digestible  which  are  most  ac- 
ceptable to  the  palate.  Do  not  leave  the  table  hungry. 
Take  animal  and  vegetable  products,  and  drink  accord- 
ing to  the  want  of  instinct.  The  diet  which  in  healthy 
subjects  is  conducive  to  health  is  the  best  diet  for  dys- 
peptics. It  is  a  fallacy  to  suppose  that  in  dyspepsia  the 
organs  of  digestion  need  a  prolonged  rest.  Patients 
should  not  be  afraid  to  rely  upon  their  digestive  powers. 
Perfect  cures  have  been  obtained  byfoUowing  the  in- 
stincts of  nature.  Dyspepsia  is  most  common  in  the 
better  educated  classes,  because  they  endeavor  to  regu- 
late their  diet  on  scientific  principles. 
A  paper  on 

DOUBLE   SYNCHRONOUS  AMPUTATIONS 

was  read  by  Dr.  W.  C.  Lynde,  of  Erie  County,  in  which 
he  presented  the  statistics  of  a  large  number  of  cases. 
The  same  writer  then  read  a  paper  on  the 

FUNCTIONS  OF  THE  AURICLES. 

He  maintains  that  the  auricles  do  not  contract,  and  that 
a  suction  force  is  exerted  on  the  part  of  the  right 
ventricle. 

Dr.  Austin  Flint,  Jr.,  said  although  the  walls  of  the 
auricles  are  much  thinner  than  the  walls  of  the  ventricles, 
they  are  composed  of  muscular  tissue,  and  do  contract. 
He  had  seen  them  contract  many  times  in  operations  on 
the  lower  animals.  In  man  there  are  no  valves  guarding 
the  openings  of  the  veins  into  the  auricles.  The  con- 
traction of  the  muscular  fibres  constricts  the  openings  of 
these  veins  and  prevents  the  regurgitation  of  the  blood. 
He  does  not  believe  in  the  suction  force  of  the  ventricles. 

Dr.  Austin  Flint,  Sr.,  described  the  contraction  of 
the  auricles  and  the  production  of  a  heart-murmur  which 
was  caused  by  the  contraction. 

Dr.  Moore,  of  Monroe  County,  described  some  ex- 
periments made  by  him  and  others  in  1838,  at  a  time 
when  we  knew  little  or  nothing  of  heart  disease.  This 
was  the  starting-point  of  our  knowledge  of  heart-sounds. 
The  contraction  of  the  auricles  is  as  easily  seen  as  the 
contraction  of  the  ventricles.  It  requires  simply  to  be 
looked  at  in  order  to  be  known. 

Dr.  Austin  Flint  described  the  jugular  pulse  as  due 
to  the  contraction  of  the  right  ventricle  and  also  to  the 
contraction  of  the  auricle.  The  presystolic  murmur  is 
due  to  the  contraption  of  the  auricle  and  is  produced,  not 
by  a  passive  flow  of  blood  from  the  auricle  to  the  ventricle, 
but  by  an  active  force. 


Dr.  Ross  related  a  case  of  rupture  of  the  risht  ventricle^ 
from  which  he  argued  that  the  force  to  produce  this  re- 
sult must  have  been  due  to  the  contraction  of  the  auricle. 

The  President  asked 

WHAT    WAS    THE    USE   OF    HAVING    A    MUSCLE    IN    THE 
WALL  OF   THE  AURICLE 

if  it  had  no  action  ? 

Dr.  Lynde  closed  the  discussion.  He  had  many  times 
experimented  on  different  animals,  by  introducing  a 
canula  and  trochar  directly  into  the  auricle,  and  had  never 
seen  the  blood  well  up  in  the  canula^  while,  when  the 
same  instrument  is  introduced  into  the  ventricle,  the 
blood  is  thrown  to  some  distance.  It  would  not  do  to 
have  the  veins  empty  directly  into  the  ventricles. 


Wednesday,  November  19TH — Second  Day — Morn- 
ing Session. 

The  Association  was  called  to  order  at  10  a.m. 

Dr.  Gouley  suggested  a  plan  that  the  Association 
should  have 

A   CITY  HEADQUARTERS,    A  PLACE    THAT   COUNTRY  MEM- 
BERS COULD   REGISTER  AT. 

This  would  include  the  founding  of  a  library  under  the 
direction  of  the  Council.  There  was  already  formed  the- 
nucleus  of  a  library,  and  forty  journals  had  been  prom- 
ised. He  further  suggested  that  a  voluntary  fund  be 
started,  to  be  divided  into  a  library  fund  and  a  sinking, 
fund,  for  putting  up  a  building.  This  plan  was  put  in  the- 
form  of  a  motion. 

Dr.  Moore  seconded  the  motion,  and  stated  that  the 
desirability  of  such  a  plan  was  obvious,  although  there- 
might  be  pecuniary  difficulties. 

The  resolutions  were  carried. 

It  was  then  carried  that 

THE  LETTERS  **  F.S.M.A."  PLACED  AFTER  A  NAME  IN  ANY 
SCIENTIFIC  PAPER  SHOULD  BE  OFFICIALLY  KNOWN  TO 
REPRESENT  THE   ASSOCIATION. 

Dr.  S.  B.  Hubbard,  of  New  Haven,  and  Dr.  H.  B.. 
Ransom,  of  Iowa,  were  invited  to  sit  as  delegates. 
Dr.  Allen,  of  Rensselaer  County,  read  a  paper  on 

DIARRHOEA   FROM   DISEASE   OF  THE   PANCREAS. 

The  history  of  a  case  was  given  that  the  doctor  called 

ADIPOSE   DIARRHCEA, 

in  a  man  about  sixty  years  of  age.  The  stools  were  not. 
very  fluid,  but  contained  matter  looking  like  melted  fat. 
There  was  pain  at  umbilicus  and  borborygmi  just  before 
the  stools.  The  patient  had  three  or  four  movements  a 
day,  the  odor  of  which  was  unbearable.  The  faeces  pre- 
sented bundles  of  fasciculi  surrounded  by  fat ;  appetite 
variable.  Pepsine  and  pancreatine,  aa.  gr.  v.,  Li.d.,  and  an 
opiate  constituted  the  treatment.  For  diet,  soft-boiled 
rice,  milk,  toast,  and  tea.  Under  this  treatment  there 
was  less  adipose  matter  in  the  stools.  There  was  coldness 
of  extremities  noticed  to  be  present.  The  patient  im- 
proved, but  had  a  relapse  from  eating  pork.  He  grew 
rapidly  worse,  and  sank  into  a  deep  stupor;  urine  partially 
suppressed,  and  an  examination  showed  one-quarter  part 
sugar,  one-sixth  albumen,  with  epithelium,  hyaline  casts^. 
and  broken  down  blood-corpuscles.  The  patient  died 
in  coma  and  no  autopsy  was  permitted.  The  case  was 
presented  to  the  Association  as  a  remarkable  one. 

THE   ADDRESS   ON   OBSTETRICS  AND   GYNECOLOGY, 

was  delivered  by  Dr.  T.  Gaillard  Thomas,  of  New  York.. 
The  author  was  asked  to  give  an  estimate  of  the  pres- 
ent status  of  obstetrics  and  gynecology.  Obstetrics  has. 
always  existed  as  an  art,  but  not  as  a  science.  William 
Hunter  first  elevated  it  to  the  position  of  a  science.. 
Since  his  time  there  has  been  a  steady  advance.  One- 
great  advance  has  been  the  discovery  of  the  relation  of 
the  low  monads  and  micrococci  floating  in  the  atmos- 
phere to  diseased  processes.  This  discovery  has  been 
of  as  great  importance  in  obstetrics  and  gynecology  as 
in  general  surgery.     In  the  parturient  process  the  open 


576 


THE  MEDICAL  RECORD. 


[November  22,  18841 


mouths  of  vessels  afford  opportunity  for  the  absorption 
of  pmson  from  without.  In  the  near  future,  antiseptic 
obstetrics  will  probably  be  the  rule.  It  never  does  any 
harm,  and  if  only  one  life  in  a  hundred  should  be  saved, 
the  extra  trouble  would  not  be  unavailing.  To  free  the 
parturient  act  from  septic  dangers  will  be  to  save  millions 
of  lives  in  the  future  ages.  The  germ  theory  has  revolu- 
tionized the  treatntent  of  puerperal  fever.  Instead  of 
quinine,  opium,  and  poultices,  antiseptic  intra-uterine  in- 
jections, containing  bichloride  of  mercury  or  carbolic 
acid  are  now  used.  Quiet  pain  by  hypodermics  of  mor- 
phine. Lower  temperature  at  once,  by  a  coil  of  running 
water.  Give  a  milk  diet  and  perfect  rest.  Extra-uterine 
pregnancy  is  now  successfully  treated  by  the  foeticide 
power  of  the  strong  galvanic  current.  The  early  diagnosis 
and  treatment  of  tubal  pregnancy  is  becoming  more  sat- 
isfactory. The  methods  of  inducing  premature  labor  have 
beconie  so  safe  and  practicable  that  in  placenta-praevia, 
uraemia,  etc.,  it  should  be  oftener  resorted  to.  The  ob- 
stetric forceps  is  the  most  life-saving  instrument  ever  de- 
vised  in  surgery.  There  have  been  few  real  improve- 
ments in  this  instrument.  Tarnier  has  recently  made 
an  improvement  by  adding  tractors.  Two  substitutes 
have  been  employed  in  place  of  Caesarean  section :  Porro's 
operation  and  laparo-electrotomy.  The  writer  thinks 
the  results  of  the  latter  operation  are  better  and  safer. 
A  successful  case  by  Dr.  Pilcher  was  reported.  The 
gynecology  of  the  future  will  be  more  allied  to  surgery 
than  medicine.  Instead  of  applying  caustics  to  an  ul- 
cerated OS,  the  lacerated  cervix  is  now  sewed  up.  Trache- 
lorrhaphy has  done  much  good  and  will  do  more.  Extir- 
pation of  the  ovary  for  various  causes  is  now  legitimate 
and  useful,  although  liable  to  abuse.  In  uterine  defor- 
mity the  forcible  dilatation  of  the  cervical  canal  is  being 
tried.  Among  drugs  the  permanganate  of  potash  is  the 
best  emenagogue. 

Afternoon  Session. 

Dr.  T.  B.  Reynolds,  of  Saratoga  County,  Vice- 
President,  presided. 

The  first  paper  read  was  by  Dr.  Darwin  Colvin,  of 
Wayne  County,  on 

venesection  in  the  convulsions  of  prjegnant  and 
parturient  women. 
The  speaker  based  his  remarks  upon  a  combined  ex- 
perience of  his  father  and  himself,  extending  over  a  total 
period  of  ninety-two  years.  Most  of  the  cases  recorded 
in  his  father's  note-books  occurred  at  a  time  when  chloro- 
form was  unknown  and  before  albuminuria  was  heard  of, 
while  his  own  cases  belonged  to  a  later  period,  when  an- 
esthetics were  in  daily  use,  bleeding  was  out  of  fashion, 
and  the  pathology  of  puerperal  eclampsia  was  beginning 
to  be  better  understood  In  none  of  his  father's  cases 
did  convulsions  occur  when  venesection  had  been  prac- 
tised upon  the  appearance  of  threatening  symptoms,  and 
even  in  those  in  which  convulsions  had  already  occurred 
a  prompt  withdrawal  of  blood  averted  the  fatal  issue. 
When  the  writer  himself  began  practice,  chloroform  was 
just  coming  into  use,  and  he  was  anxious  to  make  use  of 
it  in  puerperal  eclampsia.  In  a  case  seen  with  his  father 
a  convulsion  had  occurred,  and  consent  was  given  re- 
luctantly to  make  trial  of  the  anaesthetic.  This  was 
done,  but  the  convulsions  were  not  averted,  the  patient 
grew  worse  and  worse,  until  finally  phlebotomy  was  in- 
sisted on.  Thirty  ounces  of  blood  were  removed,  the  con- 
vulsions did  not  again  recur,  and  the  patient  recovered. 
The  author  related  a  number  of  cases  occurring  in  his 
own  practice  in  later  years  in  which  chloroform,  chloral, 
the  bromides,  and  opium  were  used  persistently,  but  the 
patients  continued  to  grow  worse ;  but  when,  finally,  vene- 
section was  with  many  misgivings  resorted  to,  improve- 
ment at  once  took  place,  and  the  lives  of  the  women 
were  saved.  In  every  case  cathartics  were  given  early, 
and  the  uterus  was  emptied  of  its  contents  as  speedily  as 
possible,  yet  no   favorable    change  occurred  until  the 


blood-letting  had  been  practised.  Irregularity  of  the 
pulse  was  insisted  upon  as  an  imperative  indication  for 
the  abstraction  of  blood.  The  author  had  never  seen  a 
fatal  case  either  in  his  father's  practice  or  in  his  own 
when  venesection  was  practised,  and  he  asserted  that  if 
this  measure  was  resorted  to  before  consciousness  had 
been  abolished  the  patient  would  not  die  of  eclampsia. 
The  lancet  was  the  sheet-anchor  in  convulsions  of  preg- 
nant and  parturient  women.  The  author  laid  down  the 
following  rules,  which  should  be  followed  in  every  case  of 
pregnancy  :  i.  Always  see  the  patient  at  least  two 
months  before  the  completion  of  her  term ;  2,  test  the 
urine  frequently ;  3,  if  there  is  much  persistent  headache^ 
open  a  vein  and  bleed  until  the  headache  is  relieved  ;  4, 
warn  the  patient  against  indulging  in  an  improper  diet ; 
5,  keep  the  4>owels  open  ;  and  6,  if  the  patient  be  seen 
for  the  first  time  at  the  beginning  of  labor,  and  convul- 
sions are  threatening,  resort  at  once  to  venesection. 

Dr.  Moore,  of  Monroe  County,  had  had  a  somewhat 
less  happy  experience  than  the  author  of  the  paper,  and 
he  had  seen  cases  that  did  not  yield  to  blood-letting. 
He  believed  that  the  only  real  cure  was  to  be  obtained 
by  eliminating  from  the  blood  the  poison  that  occasioned 
the  convulsions,  and  the  way  to  do  this  was  to  produce 
abundant  catharsis.  He  preferred  for  this  purpose  Ae 
saline  cathartics.  But  the  action  of  cathartics  is  not  in- 
stantaneous, and  in  order  to  ^ain  time  it  is  necessary  to 
avert  the  threatened  convulsion  by  some  ready  means. 
Blood-letting  will  do  this  ;  but  ether,  not  chloroform,  will 
also  do  this  and  do  it  better.  He  always  gave  ether,  in 
puerperal  convulsions  even,  and  especially,  when  there 
was  unconsciousness  with  stertorous  breathing.  He 
gave  plenty  of  it,  and  kept  the  patient  profoundly  under 
its  influence,  for  hours  if  necessary,  until  the  cathartic  had 
produced  a  copious  evacuation  of  the  bowels. 

Dr.  Pomeroy,  of  Monroe  County,  related  a  case  in 
which  convulsions  ocairred  again  and  again,  in  spite  of 
the  use  of  chloroform,  and  did  not  cease  until  the  bowels 
had  acted  thoroughly.  He  thought  the  lancet  was  use- 
ful in  certain  cases,  but  the  thing  of  prime  necessity  was 
free  catharsis. 

Dr.  Hovey  maintained  that  the  main  thing  to  do  in  a 
case  of  puerperal  eclampsia  was  to  empty  the  uterus. 

Dr.  Thayer,  of  Kings  County,  agreed  with  Dr. 
Moore  as  to  the  value  of  ether,  but  preferred  veratrum 
viride.  The  treatment  of  convulsions  by  means  of  this 
agent  was  very  extensively  practised  in  Brooklyn,  but 
the  doses,  to  be  effectual,  must  be  large — a  drachm  of  the 
tincture.  This  drug  reduces  the  rapidity  of  the  circula- 
tion speedily  and  permanently,  and  when  the  pulse  is  low- 
ered the  convulsions  will  cease.  Drachm  doses  may  be 
repeated  every  hour,  according  to  the  indications  afibrded 
by  the  pulse. 

Dr.  Cronin,  of  Erie  County,  mentioned  the  former 
division  of  eclampsia  into  apoplectic,  epileptic,  and  hys- 
terical. It  is  in  the  epileptic  form  that  bleeding  is  usefiiL 
In  closing  the  discussion,  Dr.  Colvin  insisted  again 
upon  the  irregularity  of  the  pulse  as  an  indication  for 
phlebotomy.  When  this  irregularity  occurred,  he  main- 
tained, death  was  near,  and  nothing  could  ward  it  off  but 
blood-letting. 

A  paper  by  Dr.  B.  L.  Hovey,  of  Monroe  County, 
on  "  The  Practice  of  Medicine  Forty  Years  A^o,  with 
Comparative  Position  at  Present,"  was  read  by  title. 
Dr.  C.  C.  F.  Gay,  of  Erie  County,  then  read  a  paper  on 

FRACTURE  OF  THE  BASE  OF  THE  ACETABULUM. 

It  has  been  said  that  this  fracture  rarely  occurs,  and 
that  when  it  does,  it  is  due  to  a  violent  injury  over  the 
trochanter.  But  the  object  of  the  present  paper  was  to 
show  that  it  is  of  not  so  infrequent  occurrence,  and  that 
it  may  be  produced  by  comparatively  slight  causes.  There 
may  be  a  simple  straight  fracture,  or  the  base  of  the 
acetabulum  may  be  shattered  and  broken  up  along  the 
lines  of  union  of  the  original  bones.  The  finicture  may 
occur  alone,  or  maybe  complicated  with  a  fracture  of  the 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


577 


innominate  bone,  and  the  head  of  the  femur  may  or  may 
not  be  displaced.  It  may  occur  at  any  age.  The  author 
related  a  case  seen  by  him  in  which  the  patient  had  fallen 
sixteen  feet,  striking  on*  the  right  hip.  Upon  examina- 
tion, under  ether,  there  was  found  a  slight  eversion  of 
the  foot,  with  no  shortening,  and  it  was  stated  that  crepi- 
tus was  present.  Extension  of  a  few  pounds'  weight  was 
applied  and  afforded  relief  to  the  severe  pain  complained 
of.  The  following  day  another  examination  was  made, 
and  the  same  signs  observed,  except  that  no  crepitus 
could  be  obtained.  Some  days  later  the  limb  was  again 
examined.  Soon  after,  symptoms  of  septicaemia  pre- 
sented themselves,  and  the  patient  died.  At  the  autopsy 
the  joint  was  found  filled  with  pus,  which  had  found  exit 
into  the  abdominal  cavity.  The  base  of  the  acetabulum 
was  fractured  in  three  directions,  following  the  original 
lines  of  union  of  the  bones.  The  only  prominent  symp- 
tom in  fracture  of  the  base  of  the  acetabulum  is  severe 
and  persistent  pain,  increased  by  movement  or  by  press- 
ure against  the  trochanter ;  there  is  no  shortening,  no  de- 
formity, and  no  crepitus.  This  accident,  when  there  is 
no  displacement  of  the  head  of  the  femur,  is  not  fatal, 
nor  even  dangerous,  provided  the  patient  be  let  alone. 
It  is  the  frequent  manipulation  and  examination  that 
causes  the  change.  The  management  of  a  case  of  fract- 
ure of  the  base  of  the  acetabulum  consists  simply  in  giv- 
ing perfect  rest  to  the  joint.  When  fracture  is  suspected, 
the  patient  should  be  kept  in  bed  with  the  limb  resting 
in  an  easy  position,  and  extension  may  be  made  or  not 
according  to  the  amount  of  relief  which  it  aflfords  to  the 
patient. 

There  was  no  discussion  of  this  paper,  but  several  of 
the  members  thanked  the  author  for  his  communication, 
as  having  indicated  to  them  the  correct  diagnosis  in  sev- 
eral perplexing  cases  which  they  had  under  treatment  at 
the  present  time. 

Dr.  J.  G.  Orton,  of  Broome  County,  then  related 

A  CASE  OF  TUBAL  ^REGNANCY,  AT  FULL  TERM,  OF 
FOURTEEN  YEARS*  STANDING. 

The  patient  had  passed  through  what  seemed  to  be  a 
normal  pregnancy,  at  the  expiration  of  which  some  abor- 
tive attempts  at  delivery  were  made.  These  subsided  in 
a  little  while,  and  as  time  went  on  and  no  further  symp- 
toms were  developed  the  conclusion  was  arrived  at  that 
a  mistake  in  diagnosis  had  been  made.  The  patient's 
health  declined,  and  for  eighteen  months  she  was  very 
ill  ;  but  at  the  end  of  this  time  she  began  to  improve, 
menstruation  returned,  and  she  was  soon  perfectly  re- 
stored. The  tumor  remained,  however,  and  fourteen 
years  later  she  began  to  have  a  considerable  fluid  dis- 
charge. On  examination  an  opening  was  found  in  the 
rectal  wall,  through  which  a  hard  and  movable  body  was 
felt.  A  bullet  forceps  was  introduced,  and  brought 
away  the  femur  of  a  full-grown  foetus.  In  numerous  sub- 
sequent sittings,  held  about  every  second  day,  about  one 
hundred  bones  were  removed.  The  patient  was  then  at- 
tacked with  a  diarrhoea  prevalent  at  the  time,  and  died. 
At  the  autopsy  the  right  Fallopian  tube  was  found  greatly 
enlarged,  and  on  opening  the  sac  the  remaining  bones 
of  a  full-term  foetus  were  found. 

Dr.  Nathan  Bozeman,  of  New  York  County,  then 
presented  a  communication  on 

TWO  CASES  OF  EXTRAUTERINE   PREGNANCY,  CONSIDERED 
IN   RELATION  TO  DIAGNOSIS  AND   TREATMENT. 

The  first  case  was  one  of  rupture  of  the  tube,  with 
profuse  hemorrhage  into  the  abdominal  cavity.  Laparot- 
omy was  performed,  but  the  patient  died  thirty-three 
hours  after  the  operation.  The  second  case  was  one  in 
which  abdominal  pregnancy  had  occurred,  but  gave  rise 
to  no  more  dangerous  symptoms  than  a  veiy  severe  pain 
in  the  abdomen,  which  was  controlled  by  morphine.  The 
patient  continued  for  three  years  in  excellent  health,  ex- 
cept that  she  suffered  from  violent  facial  neuralgia.  At 
this  time  menstruation  ceased,  and  the  woman  was  found 
on  examination  to  be  again  pregnant.     She  was  taken 


with  pains,  and  was  delivered  of  a  seven-and-a-half 
months'  still-born  foetus.  At  the  time  of  delivery  a  hard 
body  was  felt  presenting  in  Douglas'  cul-de-sac.  An  in- 
cision was  made,  and  the  bones  of  a  dead  foetus,  almost 
entirely  deprived  of  the  soft  parts,  were  removed.  The 
patient  made  an  excellent  recovery,  and  is  now  perfectly 
well. 

The  credit  of  being  the  first  to  insist  upon  early  laparot- 
omy in  the  case  of  rupture  of  a  tubal  pregnancy  belongs, 
the  speaker  said,  to  the  late  Dr.  Stephen  Rogers,  of  New 
York.  Since  then,  the  successful  results  obtained  by  Mr. 
Lawson  Tait  have  placed  this  operation  in  the  foremost 
rank  of  availability.  The  treatment  of  tubal  pregnancy 
in  the  early  months  consists  in  the  destruction  of  the 
foetus  by  electricity.  In  this  way  we  are  able  to  avoid 
the  graver  operation  of  laparotomy  which  becomes  im- 
perative upon  rupture  of  the  tube. 

Dr.  Arnold,  of  Albany  County,  stated  that  thece  was 
a  specimen  in  the  Albany  museum  of  a  tubal  pregnancy 
in  which  the  foetus  had  been  carried  for  fifty-two  years. 

Dr.  Newman,  of  New  York  County,  related  a  case  of 
delivery  of  the  bones  of  a  foetus  through  the  rectum  very 
similar  to  that  reported  by  Dr.  Orton.  The  speaker  ap- 
proved of  electricity  in  the  early  stages. 

Dr.  Bozeman,  in  concluding,  related  a  case  of  tubal 
pregnancy,  with  threatened  rupture,  now  under  treatment 
by  electricity.  An  interrupted  galvanic  current  from' 
fourteen  cells  is  used,  the  negative  electrode  being  passed 
up  by  the  side  of  the  uterus  with  the  positive  pole  on  the 
abdomen.  One  or  two  applications  are  supposed  to  be 
sufficient  to  cause  the  death  of  the  foetus,  but  four  are 
generally  made  to  ensure  success. 

Dr.  C.  S.  Bull,  of  New  York  County  then  read  a 
paper  on 

HYDROCHLORATE   OF    COCAINE   AS   A   LOCAL  ANiESTHETIC 
IN   OPHTHALMIC   SURGERY. 

The  first  knowledge  which  we  had  received  of  this  new  i 
application  of  the  alkaloid  of  coca,  was  obtained,  the 
speaker  said,  through  a  letter  of  Dr.  Noyes  published  in 
The  Medical  Record.  The  author  gave  the  results 
of  a  number  of  experiments  made  with  this  substance. 
In  one  hundred  and  fifty  cases  he  had  obtained  complete 
anaesthesia  of  the  conjunctiva  in  all  but  three.  The  mid- 
riatic  effects  of  cocaine  are  less  marked  than  those  of 
atropine.  Dilatation  of  the  pupil  occurs  more  slowly  and 
recedes  more  rapidly  than  when  the  latter  agent  is  used. 
As  regards  accommodation,  the  range  is  shortened  and 
the  near  point  recedes.  Recession  of  the  near  point 
begins  within  twenty  minutes  after  instillation  of  the  four 
per  cent,  solution,  increases  during  fifteen  or  twenty 
minutes,  and  then  diminishes.  Complete  paralysis  of 
accommodation  was  never  observed.  The  effects  of  the 
alkaloid  as  an  anaesthetic  are  chiefly  superficial,  though 
the  deeper  structures  are  slowly  affected.  Anaesthesia 
of  these  parts,  however,  can  be  obtained  by  injection  of 
the  solution  into  the  anterior  chamber.  The  author  re- 
lated a  number  of  cases  of  operation  upon  the  eye  in 
which  no  pain  was  experienced.  He  believed  that  every 
operation  in  ophthalmology,  with  the  possible  exception 
of  enucleation  of  the  eyeball,  might  now  be  painlessly 
performed,  and  he  predicted  that  ophthalmologists  would 
in  the  near  future  be  released  from  the  thraldom  of  ether. 
By  means  of  this  anaesthetic  also  paracentesis  of  the  drum 
membrane  could  be  performed  without  pain.  It  was 
also  of  value  in  acute  nasal  catarrh.  By  an  application, 
by  means  of  a  probe  armed  with  cotton,  to  the  mucous 
membrane  of  the  anterior  and  posterior  nares  an  acute 
coryza  could  be  cured.  After  such  an  application  in 
his  own  case  the  respiration  became  perfectly  free,  and 
remained  so  for  five  hours :  a  second  application  then 
completed  the  cure. 

Dr.  Mitchell,  of  Rensselaer  County,  desired  to  add 
his  testimony  to  all  that  had  been  said  of  the  value  of 
cocaine  hydrochlorate.  He  had  used  bromide  of  ethyl 
very  largely  in  ophthalmic  practir^,  and  considered  it^of 


578 


THE  MEDICAL  RECORD. 


[November  22,  1884. 


great  value.  Prompt  effects  were  obtained  in  one  or 
two  minutes  and  the  recovery  is  almost  as  speedy,  and  it 
was,  he  thought,  absolutely  safe  in  short  operations. 
But  this  new  anaesthetic  agent  seemed  destined  to  super- 
sede all  others.  He  thought  it  especially  useful  for  diag- 
nostic purposes  in  the  case  of  young  children,  as  even 
the  most  timid  would  allow  the  eye  to  be  handled  with- 
out shrinking  when  they  found  that  manipulation  caused 
no  sensation. 

Dr.  Squibb,  of  Kings  County,  said  that  he  had  re- 
ceived over  three  hundred  letters  asking  for  cocaine  im- 
mediately after  the  publication  of  Dr.  Noyes*  letter  in 
The  Medical  Record.  He  had  tried  to  extract  the 
alkaloid  from  coca  leaves,  but  had  as  yet  succeeded  in 
obtaining  only  about  enough  to  show  that  it  really  was 
the  hydrochlorate  of  cocaine.  The  price  of  the  drug 
was  formerly  $2.50  per  gramme  (15  grains),  but  was  now 
about  fifty  cents  a  grain,  and  was  likely  to  be  more  ex- 
pensive before  it  became  cheaper. 

Dr.  P'rederick  W.  Putnam,  of  Broome  County,  read 
a  paper  entitled 
A  report  of  a  cask  of   dislocation  of  the  first 

PHALANX   OF  THE  THUMB    FORWARD. 

Few  such  cases  have  ever  been  reported.  In  the  case 
cited,  a  boy  ten  years  of  age  fell  from  a  swing,  dislocat- 
ing the  first  phalanx  of  his  thumb  forward.  There  was 
severe  pain  but  very  little  swelling.  The  luxation  was 
readily  reduced,  and  the  case  did  well.  (The  original 
report  of  this  case  appeared  in  vol.  xxv.  of  The  Medi- 
cal Record.) 

Dr.  Jonathan  Kneeland,  of  Onondaga  County,  had 
his  paper  on  "  Common-Sense  vs.  Hypothetical  Medica- 
tion in  Treating  Chronic  Diseases,  **  read  by  title. 

Dr.  John  P.  Gray,  of  Oneida  County,  next  read  his 
paper  entitled 

insanity — preventive  measures. 
•  The  idea  of  his  paper  was  to  give  a  few  hints  on  the 
prevention  of  insanity.  Modern  science  has  suggested 
health  boards  which  are  authorized  to  proclaim  the  laws 
of  hygiene  and  enforce  them.  In  contagious  diseases 
persons  can  even  be  removed  from  their  homes  and  iso- 
lated. Compulsory  vaccination  is  the  extremest  step 
that  has  been  taken  in  this  direction.  In  ordinary  dis- 
eases, however,  the  individual  is  left  to  his  own  discre- 
tion. Insanity  is  a  disease  of  frequent  occurrence,  and 
to  a  great  extent  within  legal  control.  This  is  a  neces- 
sity to  protect  the  public  as  well  as  the  patient  Over 
twelve  thousand  persons  are  confined  in  asylums  iii  New 
York  State.  Medical  men  have  a  sreat  responsibility  in 
this  matter,  as  only  they  can  commit  to  asylums. 

CAN   ANYTHING  BE    DONE  BY  GENERAL  PRACTITIONERS  TO 
PREVENT  THE   BEGINNING  OF   INSANITY? 

The  habits  of  body  and  mind,  emotions,  disposition,  etc., 
must  all  be  carefully  considered.  Insanity  means  sickness 
of  body  producing  sickness  of  mind.  The  average  medical 
man  thinks  of  insanity  as  the  last  thing  liable  to  happen. 
Physicians  in  large  practice  often  say  they  see  very  little 
of  insanity.  The  reason  of  this  is  probably  that  persons 
having  a  family  physician  are  less  liable  to  suffer  from  se- 
vere depreciation  in  health,  which  leads  to  insanity.  An 
early  recognition  of  9k  flagging  of  the  nervous  system  is  of 
the  first  importance.  Rest  and  food  are  then  of  greater 
importance  than  travel.  Sedatives  and  narcotics  disorder 
nutrition,  and  do  more  harm  than  good ;  if  they  are  much 
used,  the  patient  is  apt  to  go  from  hypochondriasis  to 
melancholia,  often  ending  in  suicide.  .  Chalybeates,  milk, 
and  malt,  and  nourishing  food,  do  better  than  sedatives. 

CHILDREN  AND  YOUTH  ARE  SENT  TO  SCHOOL  TOO  SOON 
AFTER  RECOVERING  FROM  DISEASES  LIKE  SCARLATINA 
AND  MEASLES. 

They  are  thus  apt  to  contract  such  affections  as  hys- 
teria and  chorea.  An  early  recognition  of  changes  in 
the  character  is  of  the.  greatest  importance.  An  unnatu- 
ral timidity  or  anxi  'f  i*are  among  the  earliest  changes. 


Patients  must  be  taught  to  resist  such  tendency,  and 
their  nourishment  be  increased  in  every  way.  They 
must  be  treated  as  sick  persons  when  in  this  uncertain 
mental  state,  due  to  disordered  health.  At  the  same 
time  the  patient's  apprehensions  should  not  be  aroused 
— loss  of  sleep  and  too  little  food  generally  precede  such 
a  state.  The  early  stages  of  alteration  in  health  and 
character  can  be  often  best  recognized  and  overcome  by 
the  family  physician. 


Evening  Session. 

Dr.  Gross,  of  Philadelphia,  being  present,  was  invited 
to  sit  as  a  delegate. 

Dr.  Stephen  Smith,  of  New  York,  submitted  the  con- 
clusions of  a  paper  on 

excision  of  the  knee  in  preference  to  amputation 

IN  CERTAIN   deformities  OF  THE   LEG. 

The  class  of  cases  referred  to  were  described  as  flexions 
of  the  leg  due  to  chronic  disease  of  the  joint,  or  from 
other  causes,  which  prevented  the  limb  from  being  straight- 
ened so  as  to  bring  any  part  of  the  foot  to  the  ground. 
In  these  cases  the  joint  is  not  always  seriously  com- 
promised, but  the  long-continued  flexion  has  led  to  such 
a  contracture  of  parts  that  it  is  impossible  to  put  the  limb 
in  a  useful  position  without  excision.  The  operation 
gives  much  better  results  as  regards  future  usefulness  of 
the  limb  than  amputation. 

Dr.  'Gross,  of  Philadelphia,  described  an  operation 
devised  by  his  father,  by  which  the  partial  anchylosis  of 
the  knee  may  be  overcome. 

Dr.  E.  M.  Moore,  of  Rochester  approved  of  excision 
in  the  class  of  cases  referred  to  in  the  paper. 

Dr.  George  Harrison,  of  New  York,  read  a  paper  on 

THE   CURETTE,    ns    PLACE   AND    ITS    POWER  IN   UTERINE 
THERAPEUTICS. 

Two  problems  presented  themselves  as  to  its  use. 
First,  to  determine  what  conditions  demand  its  use,  and 
second,  the  best  method  of  using  it.  It  was  very  useful 
in  removing  morbid,  soft  structures  from  the  inner  sur- 
fajce  of  the  uterus. 

A  paper  on 

THE     RELATIONS     BETWEEN     TUBERCULOSIS,    JOINT     DIS- 
EASE,  AND   GENERAL  TUBERCULOSIS, 

was  read  by  Dr.  Dennis,  of  New  York. 

Recent  pathological  researches  have  shown  that  joint 
disease  are  primarily  generally  due  to  tuberculosis  and 
very  rarely  to  traumatism.  Clinical  facts  show  that  a 
close  relation  exists  between  acute  miliary  tuberculosis 
and  local  tuberculosis.  Tuberculosis  starts  from  a  focus, 
and  this  focus  is  a  diseased  lymphatic  gland.  The  central 
cheesy  foci  situated  in  diseased  glands  afford  means  for 
the  development  of  the  disease.  He  then  gave  the  his- 
tory of  a  case  in  which  a  cheesy  mass  was  taken  from  a 
diseased  wrist-joint,  and  the  microscope  showed  it  to 
contain  bacilli  tuberculosis.  The  patient  some  weeks 
after  died  of  acute  miliary  tuberculosis.  This  is  the  roost 
important  link  showing  the  relation  between  the  two 
affections.  Acute  miliary  tuberculosis  is  an  infectious 
disease,  and  may  be  developed  by  inoailation  or  by  in- 
haling tuberculous  material.  The  removal  of  the  cheesy 
glands  which  contain  the  foci  of  the  disease  is  the  easiest 
means  of  eradicating  it.  Marked  improvement  in  cases 
will  generally  follow  the  removal  of  the  cheesy  masses. 
P^xamine  the  character  of  the  discharges  in  every  case  to 
determine  the  presence  of  bacilli  of  tuberculosis.  The 
greatest  danger  from  tubercular  joints  is  acute  miliaiy 
tuberculosis. 

Dr.  Gross  said  primary  articular  tuberculosis  was  iden- 
tical with  tuberculosis  of  testicle  and  other  parts  of  the 
body,  and  this  connection  was  shown  in  the  cause  of  death. 
He  advocated  the  bpening  of  the  joint  and  removal  of  dis- 
eased tissue  and  then  sprinkling  the  parts  with  iodoform. 

Dr.  Dennis  then  presented  some  specimens  of  the 
disease. 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


579 


Dr.  W.  T.  Lusk  read  a  paper  on 

THE  MANAGEMENT  OF  BREECH  CASES  IN  WHICH  BOTH 
LOWER  EXTREMITIES  ARE  BENT  UP  PARALLEL  TO  THE 
ANTERIOR  SURFACE  OF  THE  CHILD. 

In  these  cases  Nature  most  often  fails  to  finish  her 
work.  Emergencies  rarely  arise  before  the  breech  has 
descended  into  the  brim.  Many  object  to  the  use  of  in- 
struments in  these  cases,  but  experience  recommends 
their  use  in  cases  where  manual  manipulation  is  of  no 
avail  The  chief  objection  to  the  forceps  is  that  it  is  de- 
signed to  take  only  the  head.  If  applied  to  the  breech 
it  may  slip  off  or  break  the  pelvic  bones,  lacerate  the 
toft  parts,  or  kill  the  child,  sometimes  injuring  the  soft 
parts  of  the  mother.  Since  the  introduction  of  the  trac- 
tion-forceps a  new  impulse  has  been  given  to  the  use  of 
forceps.  The  use  of  forceps  is  inadmissible  unless  the 
breech  does  not  engage  the  brim  of  the  pelvis.  The  ex- 
traction of  the  child  must  not  be  made  an  exhibition  of 
strength.  But  little  force  is  needed  Traction  force  is 
most  successfully  used  during  the  pains.  If  the  forceps 
fails  from  any  cause,  or  is  inadmissible,  the  employment 
of  the  fillet  is  admissible.  Dorso-posterior  position 
calls  for  especial  caution  when  traction  is  made  from  the 
groin.  The  main  drawback  to  the  use  of  the  fillet  is  the 
difficulty  of  passing  it  around  the  thigh  in  most  of  those 
cases  in  which  it  is  most  useful.  The  objection  to  the 
blunt  hook  is  due  not  to  inherent  defects  in  the  instru- 
ment, but  to  want  of  care  in  its  use. 

Dr.  Thomas  H.  Manley  read  a  paper  on 

WOMEN  AS   MIDWIVSS, 

in  which  he  advocated  their  employment  among  the 
working  classes,  and  the  opening  of  schools  for  their 
education. 


Thursi>av,  November  2oth — Third  Day — Morning 
Session. 

The  Association  wad  called  to  order  at  9.30  a.h. 

A  preamble  and  resolutions  on  the  death  of  Dr.  John 
G.  Adams  wer#  offered  by  Dr.  Purple  and  adopted  by 
the  Association. 

dr.  GOULEY  THEN   ASKED   EVERY  MEMBER  OF  THE   ASSO- 
CIATION TO   FURNISH  HIM   WITH  THEIR   PICTURE. 

Cards  containing  an  order  on  a  photographer  would  be 
furnished  them,  and  he  only  wished  to  have  one  picture 
left  for  himself.  He  abready  had  their  autographs  and 
he  wished  to  remember  them  all  personally. 

Dr.  Flint,  Sr.,  then  offered  resolutions  thanking 
Messrs.  Carnegie  and  Vanderbilt  for  their  recent  mu- 
nificent gifts  to  the  cause  of  medical  science.  Unani- 
mously carried. 

The  committee  on  nominations  reported  the  following 

officers   FOR  THE   ENSUING  YEAR  : 

President — Dr.  John  P.  Gray,  of  Oneida  County. 

Vice-Presidents— ^cxya^  District,  Dr.  W.  H.  Robb, 
of  Montgomery  County ;  Third  District,  Dr.  J.  G.  Orton, 
of  Broome  County;  Fourth  District,  Dr.  Joseph  O. 
Greene,  of  Erie  County ;  Fifth  District,  Dr.  J.  C.  Hutch- 
inson,  of  Kings  County. 

New  Members  of  Council— Ynst  District,  Dr.  William 
Gillis,  of  Franklin  County ;  Second  District,  Dr.  R.  C. 
McEwen,  of  Saratoga  County ;  Third  District,  Dr.  Fred- 
crick  Hyde,  of  Cortland  County ;  Fourth  District,  Dr. 
Darwin  Colvin,  of  Wayne  County ;  Fifth  District,  Dr.  J. 
W.  S.  Gouley,  of  New  York  County. 

Report  unanimously  adopted  by  the  Association. 

Dr.  Austin  Flint  then  delivered  an 

ADDRESS  ON  MEDICINAL  AND  NON-MEDICINAL  THERA- 
PEUTICS. 

The  scope  of  his  remarks  was  to  define  the  term 
therapeutics,  which  may  denote  drugs  only,  or,  in  a 
broader  sense,  any  means  or  appliances  for  the  cure  of 
disease.  It  is  popularly  considered  to  be  the  chief 
business  of  physicians  to  use  drugs.     The  prevailing 


sentiment  at  present  is  that  a  doctor  without  drugs  is 
like  the  play  of  "  Hamlet "  without  Hamlet.  A  case 
was  cited  in  which  a  patient  who  had  recovered  from 
pneumonia  without  the  use  of  drugs  complained  of  the 
inattention  of  the  physician.  Professional  visits  without 
a  prescription  are  often  deemed  useless  by  the  patient. 
In  the  popular  sense,  medicine  means  drugging.  A 
knowledge  of  anatomy  and  physiology  are  not  appre- 
ciated by  the  public.  A  physician  should  not  be  con- 
sidered only  as  a  dispenser  of  drugs.  It  often  takes 
better  judgment  to  withhold  drugs  than  to  give  them. 
Nothing  is  easier  than  to  give  drugs.  The  time  will  come 
when  the  doctor  will  be  considered  a  mediccU  counsellor^ 
and  this  reformation  must  take  place  in  the  public  mind. 
Nature  is  always  the  efficient  curative  agent,  and  most 
diseases  tend  by  themselves  to  recovery.  It  is  to  this 
fact  that  irregular  systems  of  medicine  owe  their  popu- 
larity, especially  in  regard  to  infinitesimal  doses.  There 
is  considerable  diversity  of  opinion  among  physicians  as 
to  the  effects  of  drugs ;  some  are  too  confident  of  their 
powers,  and  others  too  sceptical. 

There  are  pharmacomaniacal  doctors  as  well  as  pa- 
tients. Each  new  remedy  is  eagerly  accepted  and  the 
old  one  discarded.  The  sceptical  doctor  shows  the  re- 
verse picture,  and  the  truth  lies  somewhere  between 
these  extremes.  We  must  be  satisfied  that  potential 
drugs  are  clearly  indicated  before  using  them.  Clinical 
experience  is  the  only  rational  ground  upon  which  drugs 
are  to  be  used,  and  hence  the  importance  of  close  obr 
servation.  The  results  of  experiments  on  lower  animal^ 
must  be  accepted  with  caution.  It  was  empiric  knowl- 
edge that  first  led  to  the  use  of  such  drugs  as  cinqhona 
and  mercury,  although  now  we  think  they  may  act  as 
parasiticides.  Theoretical  knowledge  has  rarely  been  of 
much  clinical  use.  The  parasitic  idea  of  the  etiology 
of  disease  offers  a  great  future  for  therapeutics  in  the 
line  of  discovery  of  parasiticides.  Non-medicinal  thera- 
peutics are  not  much  appreciated  by  the  pharmacomani- 
ac  Harm  may  be  done  by  the  use  of  non-medicinal  agen- 
cies as  well  as  b^  an  injurious  use  of  drugs.  Diet  is  an 
essential  factor  m  therapeutics,  and  we  must  keep  in 
view  that  there  is  never  danger  from  over-nutrition.  The 
lethal  agency  in  exhausting  diseases  is  always  denutrition 
and  starvation.  If  patients  can  digest  and  assimilate  food 
they  cannot  be  overfed.  The  best  principles  of  thera- 
peutics are  in  accord  with  common  sense.  There  must 
be  a  regard  for  nature's  wants,  and  appetite  and  taste 
generally  show  what  is  needed.  In  cases  like  the  essen- 
tial fevers,  where  the  appetite  is  gone,  reliance  must  be 
placed  on  milk  and  eggs.  With  regard  to  beef-tea,  ex- 
tracts, etc.,  the  nutriment  is  almost  ni7,  although  they 
act  as  stimulants  to  the  digestive  fluids.  Beef-toa  has 
been  compared  to  urine.  Leube^s  solution  contains  the 
equivalent  of  solid  flesh,  and  Rosenthal  has  made  it 
more  palatable.  Most  nervous  diseases  are  due  to  de- 
ficient nutrition.  Is  alcohol  a  food  ?  To  a  certain  extent 
it  is,  inasmuch  as  it  is  not  expelled  from  the  body  as  al- 
cohol. It  should  not  be  withheld  in  disease,  even  if  it  is 
not  always  desirable  in  health ;  the  tendency  of  late  years 
has  been  to  use  alcohol  rather  more  restrictedly. 

In  certain  cases  of  phthisis,  alcohol  retards  the  disease 
and  it  sustains  life  in  typhoid  fever.  It  prevents  tissue 
waste  and  has  antiseptic  properties.  The  term  to  catch 
cold  is  indefinite  and  does  harm  among  the  laity.  Sick 
rooms  are  poorly  ventilated,  and  sponging  deemed  haz- 
ardous; in  pneumonia,  especially,  is  there  a  popular 
prejudice  againt  cold.  Few  diseases  are  due  directly  to 
cold,  and  a  fever  patient  never  catches  cold.  The  men- 
tal influence  of  the  doctor  on  the  patient  is  important 
Some  never  succeed  because  they  cannot  inspire  confi- 
dence^faithy  and  hope.  One  class  of  physicians  are  too 
sanguine,  and  thus  err  in  prognosis ;  another  class  are 
too  pessimistic.  A  gloomy  prognosis  may  contribute  to 
its  fulfilment.  Faith  cures  show  the  influence  of  the 
mind  on  the  body,  and  physicians  may  learn  something 
from  them.     The  introduction  of  the  term  neurcuthenia 


i 


58o 


THE  MEDICAL  RECORD. 


[November  22,  1884. 


has  done  harm.      Too  much  introspection    must    be 
avoided,  and  the  sanitary  effects  of  work  not  overlooked. 
Resohitions  of  sympathy  with  Dr.  Sayre  in  his  illness 
were  carried. 

RESOLUTIONS  OF  THANKS  TO  DR.  J.  W.  S,  GOULEV  FOR 
THE  ENERGY  DISPLAYED  BY  HIM  IN  CONNECTION  WITH 
THE   ASSOCIATION 

were  also  carried. 

Dr.  John  P.  Gray,  the  President-elect,  then  took  the 
Chair.  He  made  a  brief  speech  in  which  he  stated  that 
the  Association  was  not  an  offshoot,  and  represented 
neither  new  code,  old  code,  nor  no  code,  but  was  in- 
tended to  keep  up  the  fellowship  and  feeling  that  had  for- 
merly existed  in  the  profession. 


Afternoon  Session. 

The  first  paper  read  was  by  Dr.  Caspar  Griswold, 
of  New  York  County,  on 

FALSE   ALBUMINURIA. 

There  were  two  classes  of  cases  considered  by  the 
speaker :  i.  Those  in  which  the  urine  does  not  contain 
albumen,  but  in  which  a  precipitate  resembling  albumen 
is  thrown  down  by  the  ordinary  tests.  2.  Cases  in  which 
the  urine  does  contain  albumen,  but  this  albumen  is  not 
excreted  by  the  kidneys,  and  consequently  is  not  a  sign 
of  nephritis.  The  author  described  the  methods  used  by 
himself  in  order  to  discriminate  between  different  precip- 
itates, and  concluded  by  insisting  upon  the  necessity  of 
correct  methods  in  testing  the  urine  for  albumen. 

Dr.  Samuel  W.  Smfth,  of  New  York  County,  then 
presented  a  communication  entitled 

THE  early  use  OF  THE  KNIFE  IN  NiEVUS  OF  THE  CAV- 
ERNOUS ANGIOMA  VARIETY  AS  CONTRASTED  WITH 
OTHER  MODES   OF   OPERATION    FOR   REMOVAL. 

The  author  urged  an  early  operation  by  the  knife,  be- 
cause of  the  rapid  growth  of  the  tumors,  and  reported 
two  cases  in  support  of  his  preference. 
The  following  papers  were 

READ    BY  TITLE 

and  referred  to  the  Committee  on  Publication. 

"  Stretching  of  the  Nasal  and  Infraorbital  Nerves  in 
Ciliary  Neuralgia,"  by  Dr.  C.  G.  Ross,  of  Chemung 
County ;  a  case  of  "  Ovarian  Cyst  with  Operation,"  by 
Dr.  T.  M.  Lloyd ;  "  Organic  Disease  of  the  Brain  not 
a  Constant  Factor  in  Insanity,"  by  Dr.  Simeon  T.  Clark, 
of  Niagara  County  ;  **  Supporting  the  Perineum  in  the 
Act  of  Parturition,"  by  Dr.  Jacob  Hardtman,  of  New 
York  County ;  **  Report  of  a  Case  of  Gunshot  Wound 
of  the*  Stomach,  Recovery,"  by  Dr.  John  H.  Hinton,  of 
New  York  County. 

Dr.  E.  G.  Janeway,  of  New  York  County,  next  read 
a  paper  on 

ABSCESS   OF  THE   LIVER. 

The  doctor  has  seen  a  comparatively  large  number  of 
cases  of  abscess  of  the  liver  during  the  past  year,  and 
thinks  that  the  disease  is  not  so  infrequent  in  this  cli- 
mate as  is  usually  supposed.  The  abscess  may  be  single 
or  multiple.  The  idiopathic  form  is  to  be  distinguished 
from  that  ocurring  when  there  is  infection  through  the 
portal  circulation.  Sometimes  several  small  infective 
abscesses  may  coalesce  and  form  a  single  abscess,  resem- 
bling the  idiopathic  form.  During  the  present  year  the 
doctor  has  met  seven  cases  ;  of  these  three  died  and  four 
recovered.  Of  those  that  recovered,  in  three  cases  the 
abscess  was  opened  by  operation  and  one  opened  spon- 
taneously. 

Dr.  J.  Lewis  Smith,  of  New  York  County,  then  read 
ajpaper  on 

DIPHTHERITIC   CROUP.  ^ 

He  stated  that  croup  was  usually,  but  not  always,  a 
local  manifestation  of  diphtheria.  Any  severe  inflam- 
mation of  the  larynx  might  result  in  the  formation  of  a 


pseudo-membrane.  He  related  a  case  of  membranous 
croup  in  a  child,  twenty-five  months  of  age,  due  to 
"catching  cold."  *  Croup  did  not  occur  always  from 
propagation  of  the  specific  inflammation  from  the 
pharynx  and  fauces,  but  might  be  the  first  manifestatioD 
of  the  disease.  It  might  also  occur  in  the  course  of 
diphtheria,  notwithstanding  the  most  thorough  disinfec- 
tion of  the  faucial  exudation.  Whenever  in  a  case  of 
diphtheria  the  patient  became  hoarse  or  presented  any 
other  signs  of  implication  of  the  larynx,  treatment  by 
inhalations  of  lime-water  was  imperative.  When  any 
marked  dyspnoea  was  present,  not  more  than  one  in 
eight  patients  could  be  saved  without  tracheotomy.  The 
room  should  be  filled  with  steam  from  a  croup-kettle  or 
atomizer ;  to  the  lime-water  in  the  atomizer  liquor  po- 
tassae,  in  the  proportion  of  one  and  a  half  per  cent,  being 
added. 

Dr.  Rochester,  of  Erie  County,  related  a  case  in 
which  he  employed  a  mixture  of  iodoform  and  bismuth 
(one  part  to  two)  in  insufflation  ;  no  other  treatment  was 
given  except  stimulation. 

Dr.  Reese,  of  Kings  County,  since  he  had  used  kero- 
sene in  inhalation,  had  never  had  a  fatal  case  of  croup. 

Dr.  Moore,  of  Monroe  County,  had  found  frequent 
insufflations  of  bicarbonate  of  soda  most  efi*ectual  for  dis- 
solving membrane.     ' 

Dr.  Austin  Flint,  Jr.,  related 

SOME  TYPICAL  CASES  OF  DIABETES  MELLITUS  NOT  BEFORE 
REPORTED. 

They  illustrated  the  value  of  arsenite  of  bromine  (three 
to  five  drops  of  Clemens'  solution  three  times  a  day)  in 
conjunction  with  a  rigid  anti-diabetic  regimen.  In  con- 
clusion he  quoted  a  statement  of  Cantani  that  diabetes 
was  readily  curable  provided  only  that  treatment  be  be- 
gun in  an  early  stage. 

Dr.  Clark,  of  Vermont,  said  that  in  his  own  case  he 
suffered  greatly  from  dyspepsia  when  starchy  foods  were 
excluded.  He  found  sugar  in  his  urine  #hen  the  specific 
gravity  was  reduced  to  1.003. 

Dr.  Fifiene,  of  Boston,  related  the  case  of  his  son, 
who  suffered  from  diabetes  after  the  bite  of  a  bull-dog. 
He  did  not  believe  that  dieting  would  ever  cure  diabetes 
in  the  young,  and  if  it  did  in  the  old  it  must  be  because 
of  some  constitutional  difference. 

Dr.  T.  W.  Ross,  of  Chemung  County,  reported  a  case 
of 

RUPTURE   OF  THE   UTERUS, 

occurring  in  a  woman  with  narrow  pelvis,  who  had  had 
nine  previous  pregnancies,  none  of  them,  however,  going 
to  term. 

Dr.  Bontecou,  of  Rensselaer  County,  then  exhibited  a 
patient  illustrating 

A   CASE   OF    CONSERVATIVE    SURGERY  AND    ITS  RESULTS. 

The  patient  was  shot  in  the  late  war  and  suffered  a 
very  extensive  injury  of  the  shoulder-joint  Exsection 
was  performed  some  month  later,  as  much  of  the  perios- 
teum having  been  saved  as  possible.  There  had  been 
a  considerable  reproduction  of  the  shaft  of  the  humerus. 

A  paper  was  then  read  by  Dr.  J.  W.  S.  Gouley,  of 
New  York  County,  entitled  "Report  of  a  Case  of  Liga- 
ture of  the  Primitive  Iliac  Artery  for  Diffuse  Aneurism 
of  the  External  iliac  Artery." 

The  session  was  then  adjourned. 

At  the  close  of  the  session  on  the  third  day  two  hun- 
dred and  thirty-eight  members  had  redstered. 

The  Fellows  residing  in  New  York  County  entertained 
the  Association  at  supper  in  the  evening  at  the  Murray 
Hill  Hotel. 

The  programme  for  Friday  included  surgical  opera- 
tions at  Bellevue  Hospital  at  10  a.  m.,  an  exhibition  of 
various  bacilli  at  1 1  a.  m.,  and  an  excursion  to  the  hos- 
pitals on  Blackwell's,  Ward's,  and  Randall's  Islands  at 
noon. 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


581 


(£>owesvion&ence. 


OUR  LONDON  LETTER. 

(From  our  Special  Correspondent) 

CHANGES     IN    THE    ARMY    MEDICAL     DEPARTMENT — EX- 
AMINATION      FOR       PROMOTION — ANOTHER       MEDICAL 

JOURNAL — ^VICTORIA      AND     LONDON     UNIVERSITIES 

MEDICAL  DEGREES — CRISIS  IN  THE  LONDON  MEDICAL 
SCHOOLS — PROPOSED  UNION  OF  THE  TWO  LONDON 
COLLEGES — REFORM  OF  THE  COLLEGE  OF  SURGEONS — 
SIR  LYON   PLAYFAIR   AND   MEDICAL   REFORM. 

London,  November  z,  1884. 

Considerable  changes  are  being  effected  in  the  Army 
Medical  Department,  and  some  of  them  are  giving  rise 
to  disaffection,  if  not  hostility.  First  of  all  the  De- 
partment is  to  be  furnished  with  a  brand  new  name — 
**  The  Medical  Staff. "  This  is  not  sufficiently  dignified  for 
some,  who  think  it  entitled  at  least  to  the  prefix  "  Royal," 
which  has  indeed  been  recommended  by  two  important 
committees  of  inquiry ;  but  for  some  reason,  compre- 
hensible perhaps  to  the  official  mind,  has  been  withheld. 
It  is  said,  however,  that  it  may  even  yet  be  conferred. 
I  do  not  know  that  it  will  do  our  army  surgeons  much 
good,  but  if  they  desire  an  empty  distinction  of  the  kind, 
their  arduous  services  entitle  them  to  the  horior. 

Army  surgeons  have  a  further  grievance  :  honors  and 
distinctions  are  conferred  freely  enough  on  combatant 
officers,  even  when  they  have  run  no  particular  risks,  but 
are  only  grudgingly  awarded  in  the  fewest  possible  cases 
to  surgeons  whose  lives  have  been  freely  exposed  in  the 
performance  of  their  duty.  It  is  a  curious  thing  to  ob- 
serve that  the  name  of  the  head  of  the  Medical  Depart- 
ment appears  in  the  army  list  without  any  military 
decoration.  There  has  always  been  a  jealousy  between 
combatant  and  non-combatant  officers.  The  former 
have  affected  to  look  down  upon  their  surgeons,  except 
of  course  at  the  time  their  services  were  m  actual  de- 
mand. 

Another  important  change  is  also  to  be  inaugurated. 
An  examination  for  promotion  to  the  rank  of  Brigade- 
Surgeon  is  to  be  instituted ;  and  the  feeling  with  which 
this  regulation  is  received  by  those  who  will  have  to  be 
examined  is  naturally  the  reverse  of  pleasant.  The 
Duke  of  Cambridge  stated  before  a  parliamentary  com- 
mittee that  to  "  examine  a  man  up  to  fifty  years  of  age  is 
hardly  fair,  and  that  if  the  heads  of  the  department  do 
their  duty  they  ought  to  judge  of  the  fitness  for  promo- 
tion of  medical  officers  without  examination.''  Speaking 
as  a  civilian  I  should  think  His  Royal  Highness  must  be 
right  There  are  some  people  who  think  examination 
can  test  everything.  It  would  open  their  eyes  if  they 
were  examined  themselves.  One  defender  of  the  new 
proposal  says  that  a  good  administrative  officer  requires 
tact  as  well  as  temper.  Fancy  examining  a  man  to  as- 
certain whether  he  possesses  such  qualifications !  An- 
other defender  asserts  that  the  examination  is  optional. 
Of  course  it  is,  but  passing  it  will  be  necessary  for  pro- 
motion ;  the  option,  therefore,  is  of  the  kind  known  as 
**  Hobson's  choice."  I  observed  some  time  ago  that  this 
question  of  examination  for  promotion  had  been  fully 
discussed  in  The  Record  in  reference  to  the  regulations 
of  the  United  States  Army.  American  Army  surgeons 
can  therefore  sympathize  with  their  British  brethren  in 
the  infliction  to  which  they  are  about  to  be  subjected. 
At  first  it  was  actually  proposed  to  examine  surgeons- 
major  in  operative  surgery ;  but  I  hear  that  this  rule  is 
to  be  modified,  and  further  that  fellows  of  one  of  the 
Royal  Colleges  of  Surgeons  are  to  be  exempted  from  the 
new  examination. 

A  new  periodical,  Tlhe  Medical  Chronicle^  appeared 
in  October.  It  may  be  regarded  as  the  organ  of  the 
Manchester  Medical  Sdiool,  as  it  is  issued  under  the 
authority  of  an  influential  committee  in  that  city.     But  it  ] 


proposes  to  give  a  full  abstract  of  current  medical  litera- 
ture. As  Manchester  is  the  seat  of  the  new  Victoria 
University  and  of  numerous  medical  charities,  there  may 
be  room  for  such  an  organ. 

Speaking  of  the  "  Victoria  "  reminds  me  that  that  uni- 
versity has  just  missed  a  great  chance  of  at  once  becom- 
ing one  of  the  most  important  medical  institutions  by 
confining  its  degrees  to  the  students  of  its  own  colleges. 
Had  it  thrown  open  its  portals  to  all  qualified  practitioners 
who  could  pass  its  examinations,  hundreds  would  have 
applied  for  its  degree,  to  whom  the  condition  of  residence 
renders  such  a  distinction  inaccessible.  But  the  Victoria 
does  not  accept  the  examinations  of  other  universities, 
not  even  of  the  London,  on  whose  evil  model  it  has  so 
largely  framed  its  regulations. 

To  other  nations  it  must  be  almost  incomprehensible 
that  the  great  bulk  of  English  practitioners  do  not  hold  a 
university  degree.  It  is  not  because  they  do  not  desire 
it,  but  because  the  English  universities  have  so  franaed 
their  regulations  as  to  drive  men  to  the  colleges  which 
confer  a  membership  or  fellowship,  but  have  no  power  to 
grant  degrees.  That  the  magic  M.D.  or  M.B.  is  coveted  is 
proved  by  the  fact  that  hundreds  go  abroad  to  get  it,  and 
thousands  go  to  Scotland.  Only  twenty  per  cent  of 
practitioners  in  England  have  any  connection  with  the 
English  universities,  while  nearly  sixty-two  per  cent 
hold  Scotch  degrees.  In  Scotland  itself,  ninety-eight  per 
cent,  of  the  practitioners  are  graduates.  You  will  say 
that  we  have  a  university  in  London,  but  that  body  has 
devised  such  a  stupid  set  of  regulations  that  a  very  small 
number  of  students  attempt  to  comply  with  them,  and  of 
those  who  begin  the  medical  career  mapped  out  for  them 
and  pass  the  earlier  medical  examinations  only  ten  per 
cent  obtain  the  full  degree.  Was  there  ever  such  a 
specimen  of  "  how  not  to  do  it  ?  " 

Just  now  the  medical  teachers  of  London  are  very 
much  concerned  about  the  facts  I  have  named  above, 
and  no  wonder  their  best  men  are  leaving  them,  going 
off  to  inferior  schools,  because  the  metropolis  with  its 
unrivalled  facilities  for  education  is  unable  to  crown  the 
edifice  with  the  recognized  distinction.  The  list  of  en- 
tries at  the  medical  schools  for  the  winter  session  s 
now  completed,  and  a  genuine  "eye-opener"  it  proves 
to  be.  The  paltry  University  of  Durham  with  its  affili- 
ated school  at  Newcastle  has  a  larger  entry  than  sev- 
eral of  the  London  schools.  Why  ?  Because  residence 
at  Newcastle  enables  the  student  to  take  a  degree,  but 
residence  at  London  does  not  No  one  can  suppose 
that  medicine  can  be  better  taught  at  Newcastle  In- 
firmary than  at  our  great  London  hospitals ;  and  yet 
these  Newcastle  students  will  soon  come  out  as  full- 
fledged  M.B.*s  or  M.D.'s,  with  a  legal  right  to  call  them- 
selves Doctor,  while  students  of  Gu/s,  St.  Bartholomew's, 
St  Thomas',  and  the  London  Hospitals,  must  be  con- 
tented to  style  themselves  plain  Mr.,  or  to  append  to  their 
names  half  a  dozen  or  a  dozen  letters,  which  are  for  the 
most  part  incomprehensible  to  the  public.  I  have  al- 
ready informed  you  that  there  was  a  talk  of  making  our 
two  Royal  colleges  into  a  university,  and  this  notion  has 
gained  ground,  until  to-day  it  has  obtained  the  support 
of  The  Lancety  and  many  teachers  would  rejoice  to  see 
it  accomplished.  It  ought  to  be  easier  with  the  mate- 
rials thus  to  hand  to  inaugurate  a  medical  university  in 
close  connection  with  the  metropolitan  schools,  than  to 
establish  an  absolutely  new  university  in  all  the  faculties. 
Our  two  colleges  have  agreed  to  unite  and  give  a  full 
diploma,  which  will  qualify  for  practice  in  every  depart- 
ment ;  but  those  who  take  that  diploma,  though  they  may 
be  members  of  both  colleges,  will  still  have  to  call  them- 
selves Mr.,  will  still  be  unable  to  sign  themselves  M.D., 
while  their  rivals  and  neighbors  who  hail  from  New- 
castle or  Aberdeen  may  write  Dr.  before  their  names  or 
M.D.  after.  Unless  something  is  done  to  remedy  this 
injustice  the  ruin  of  the  London  schools  is  to  be  antici- 
pated. In  New  York,  I  understand,  the  College  of  Phy- 
sicians and  Surgeons  confers  the  degree  of  M.D.    But  on 


582 


THE   MEDICAL  RECORD. 


[November  22,  1884. 


your  side  of  the  water  you  can  go  ahead  and  rejoice  in 
your  strength ;  here  we  are  overburdened  with  our  a^e, 
and  when  we  attempt  to  disturb  the  dust  of  centuries 
we  are  suffocated  for  our  pains. 

We  have  now  in  working  order  two  Societies  lor  the 
Promotion  of  Reform  in  the  London  College  of  Surgeons, 
and  both  bodies  have  put  forth  their  grievances.  The 
Association  of  Fellows  have  issued  a  series  of  recommen- 
dations, which  are  decidedly  liberal,  so  far  as  they  are 
themselves  concerned,  and  inasmuch  as  they  recognize 
the  existence  of  Members ;  but  they  have  no  notion  of 
making  the  latter  an  integral  part  of  the  corporation.  As 
the  recommendations  will  be  shortly  discussed  and  may 
be  considerably  modified,  I  need  not  more  fully  describe 
them.  The  Association  of  Members  is  rather  more  am- 
bitious, and  has  actually  petitioned  the  Prime  Minister  to 
assign  two  Members  of  Parliament  to  the  medical  men  of 
the  country.  I  do  not  suppose  the  petition  will  produce 
more  than  a  faint  smile  m  official  circles.  No  profession, 
as  such,  enjoys  parliamentary  representation,  and  we 
may  be  pretty  sure  that  such  an  innovation  will  not  be 
made  by  a  Government  of  which  most  of  the  members 
are  opponents  of  **  fancy  franchises." 

The  mention  of  Parliament  reminds  me  that  the  shadow 
of  a  coming  election  is  already  perceptible  in  several  quar- 
ters, and  in  one  is  of  special  interest  to  our  profession.  The 
seat  of  Sir  Lyon  Playfair  is  again  threatened  ;  at  the  last 
election  he  was  only  returned  by  a  small  majority.  He 
had  deeply  offended  a  large  section  of  his  constituents 
by  his  action  on  medical  reform,  and  a  medical  man  was 
put  in  opposition  ;  he  was,  however,  again  returned  for 
the  Universities  of  Edinburgh  and  St,  Andrews.  Since 
then  he  has  again  played  fast  and  loose  with  medical  re- 
form. He  has  no  doubt  pleased  some  of  the  Scotch  cor- 
porations, but  the  majority  of  his  numerous  medical  con- 
stituents are  disgusted  with  his  tergiversation,  and  those 
who  are  of  the  same  political  party  think  his  time-serving 
spirit  unfit  for  the  representative  of  an  academical  constit- 
uency. This  week,  therefore,  they  have  brought  for- 
ward a  candidate,  who  has  promised  to  contest  the  seat 
on  the  first  opportunity.  Unfortunately  he  is  a  lawyer  ; 
and  we  have  too  many  lawyers  in  Parliament.  He  is  a 
thorough-going  Conservative,  and  it  is  certain  that  the 
constituency  is  rather  Liberal  than  otherwise.  Further, 
though  a  large  part  of  his  address,  about  half,  is  taken  up 
with  medical  politics,  he  completely  misunderstands  them, 
and  would  be  quite  as  unendurable  to  medical  men  as 
their  representative,  as  Sir  Lyon  Playfair  himself.  Only 
a  medical  man  ought  to  be  M.P.  for  the  Universities  of 
Edinburgh  and  St.  Andrews.  It  was  a  mistake  when  Sir 
Lyon  Playfair,  as  a  Professor  of  Chemistry,  was  thought 
to  be  a  suitable  substitute  for  a  medical  candidate. 


COCAINE  HYDROCHLORATE  IN  MINOR' 
SURGERY. 

To  THE  Editor  op  The  Medical  Recokd. 

Sir  :  As  the  subject  of  cocaine  hydrochlorate  is  some- 
what prominent  just  now,  I  trust  the  following  case  will 
not  be  entirely  without  interest,  your  editorial  of  last 
week  being  partly  responsible  for  the  occurrence.  At 
the  semi-annual  meeting  of  the  Fairfield  County  Medical 
Society,  held  to-day  at  the  Bridgeport  Hospital,  one  of 
its  members.  Dr.  Wright,  of  this  city,  kindly  permitted  the 
following  experiment : 

The  doctor  had  a  small  fatty  tumor  upon  his  forehead. 
I  passed  the  needle  of  an  ordinary  hypodermic  syringe 
through  the  skin  on  one  side,  and  tried  to  pass  it  across 
the  tumor  between  it  and  the  skin,  but  did  not  succeed, 
and  so  passed  it  through  the  tumor.  Then  while  slowly 
withdrawing  it,  injected  about  six  minims  of  a  two  per  cent, 
solution  of  cocaine  hydrochlorate,  obtained  from  Foucar 
about  three  weeks  ago.  I  then  rubbed  a  few  minims  upon 
the  skin  over  the  tumor  with  my  finger.  In  five  minutes 
I  thrust  the  needle  into  the  skin  over  the  tumor  so  as  to 


draw  blood.  The  doctor  felt  what  he  described  a  "sense 
of  pressure,"  1.^.,  he  knew  that  I  was  doing  something  but 
felt  no  pain.  In  fifteen  minutes  there  was  apparently 
some  return  of  sensibility.  I  then  injected  four  minims 
more  from  the  side  opposite  to  that  from  which  the  first 
injection  had  been  made.  Dr.  Weir,  of  New  York  City, 
who  was  present  with  us  by  invitation,  then  removed  the 
tumor  through  a  single  straight  incision  about  an  inch 
and  a  half  long. 

The  sensations  of  Dr.  Wright  during  the  operation 
are  given  in  his  own  words.  No  one  timed  the  different 
steps  of  the  experiment  accurately.  I  give  my  own  esti- 
mates above  and  the  doctor  gives  his  below. 

"  The  first  injection  by  the  hypodermic   needle  was 
quite  painful  to  me,  but  as  it  was  my  first  experience  in 
its  use  upon  myself  I  presume  not  m'ore  painful  than  to 
anybody  else.    In  about  two  minutes  I  felt  a  benumbing 
sensation  in  and  about  the  tumor,  and  suggested  to  Dr. 
Wilson  that  it  was  anaesthetic.     He  pricked  it  with  the 
needle,  but    I    only  felt  the  pressure.     In  about  eight 
minutes  I  felt  as  though  sensation  was  returning  to  the 
tumor,  but  probably  I  was  wrong,  for  in  about  ten  min- 
utes the  second  injection  was  given,  of  which  I  felt  the 
initial  prick,  but  was  unable  to  locate  from  the  feeling 
the  place  of  injection,  or  the  direction  in  which  he  ran  the 
needle.     In  less  than  five  minutes  Dr.  Weir  began  the 
operation,  at  which  time  the  forehead  and  face  felt  anaes- 
thetic for  a  radius  of  three  or  four  inches.     I  felt  the 
first  cut  through  the  skin,  but  it  did  not  seem  painful,  or. 
at  most,  not  more  so  than  the  scratch  of  a  pin.     Then  I 
could  feel  the  blood  flowing  down  my  cheek,  and  hear 
the  grating  of  the  knife,  but  felt  no  pain  at  all.     I  could 
barely  distinguish  the  prick  of  the  needle  when  the  two 
stitches  were  taken.    During  and  subsequent  to  the  oper- 
ation I  felt  elated  and  buoyant,  and  was  less  conscious 
than  usual  of  fatigue  during  the  long  exercises  of  the 
afternoon,  though  on  my  feet  the  whole  time.     At  no 
time  have  I  felt  sleepy,  and  though  at  the  present  time 
of  writing,  about  seven  hours  after  the  operation,  I  have 
scarcely  had  time  to  sit  down,  I  do  not  feel  tired,  and 
expect  to  visit  several  patients  before  bed-time.    Such 
excitement  and  unusual  exertion  generally  gives  me  a 
headache,  of  which  now  I  have  not  a  particle. 

J.  W.  Wright,  M.D." 

There  can  be  no  question  that  in  this  single  instance 
the  subcutaneous  injection  of  cocaine  hydrochlorate 
transformed  a  very  painful  operation  into  a  compara- 
tively painless  one.  You  will  notice  that  Dr.  Wright 
lays  most  stress  upon  the  pain  of  the  first  injection  of 
the  drug.  F.  M.  Wilson,  M.D. 

317  Statk  Strekt,  Bridokport,  Comn., 
November  ii,  1884. 


OUR   CINCINNATI  LETTER. 

(From  our  Special  Correspondent.) 

CINCINNATI     MEDICAL    SOCIETIES — COLLEGES GUNSHOT 

SURGERY — MIDWIVES. 

The  medical  societies,  though  baffled  through  the  month 
of  September  by  the  excessive  heat,  are  now  down  to  a 
working  basis,  and  promise  some  interesting  meetings 
for  the  winter.  Foremost  and  oldest  of  all  is  the  Cin- 
cinnati Academy  of  Medicine.  This  society  has  Dr.  W. 
H.  Wenning,  of  St.  Mary's  Hospital,  as  President,  and 
George  A.  Fackler,  M.D.,  as  Secretary.  It  has  a  large 
membership  and,  except  on  election  nights,  a  fair  attend- 
ance. 

At  a  recent  meeting,  Dr.  A.  Ravogli  reported  a  case 
of  elephantiasis  of  the  leg  which  he  had  seen  during 
Dr.  Connor's  absence.  The  calf  measured  three  feet 
four  inches  in  circumference ;  the  whole  limb  was  in- 
vaded. Patient  was  eighteen  years  of  age.  The  disease 
had  its  initial  stage  in  early  childhood,  which  is  unusual. 
The  boy  weighed  three  hundred  pounds,  of  which  one 
hundred  and  eighty  pounds  were  attributed  to  the  leg. 


•November  22,  1884.] 


THE  MEDICAL  RECORD. 


583 


He  continued  in  good  health  till  twenty  four  hours  pre- 
vious to  death.  The  speaker  was  inclined  to  attribute 
death  to  an  embolus.  Said  it  might  have  been  from 
pyaemia  from  excessive  lymphangitis.  Much  interest 
was  taken  in  this  case. 

At  the  meeting  next  in  order,  Dr.  Hottendorf  read  an 
article  on  "  The  Abortive  Treatment  of  Typhoid  Fever." 
He  reported  as  occurring  in  his  practice  during  the  last 
six  years  twenty-three  cases  of  typhoid  fever,  fifteen  in 
adults  and  eight  in  children.  All  he  treated  on  the  abor- 
tive plan,  viz.,  calomel.  He  gave  one-half-gramme 
doses  every  day,  or  more  seldom  if  the  case  required, 
during  the  first  week  of  the  disease.  He  had  had  most 
gratifying  results,  viz.,  recovery  in  every  case. 

The  Cincinnati  Medical  Society  is  younger,  has  fewer 
members,  and  a  lighter  attendance  than  the  Academy  of 
Medicine,  yet  it  has  some  very  live  men  and  some  very 
live  meetings.  The  younger  members  of  the  profession 
seem  to  have  a  prominent  part  in  its  affairs  and  do  the 
most  of  the  work.  While  the  Faculty  of  the  Medical 
College  of  Ohio  belong  to  the  Academy,  the  Faculty  of  the 
Miami  Medical  College  belong  to  the  Cincinnati  Medi- 
cal Society.     This  is  3ie  differential  diagnosis. 

Dr.  Dun,  at  a  recent  meeting,  reported  a  case  of 
severe  shock  from  electricity — a  femsde  clerk  of  high 
nervous  sensibility.  The  wires  of  the  electric  light 
became  crossed  with  those  of  the  cash-ball  system  while 
she  was  operating,  and  she  received  a  terrible  shock. 
She  uttered  a  piercing  cry  and  fell  to  the  floor  uncon- 
scious. By  appropriate  treatment  she  recovered.  The 
doctor  said  we  may  expect  to  see  more  of  this  class  of 
cases  in  the  future. 

At  a    more  recent  meeting  Professor  W.  H.  Taylor, 
one  of  the  physicians  on  obstetric  duty  at  the  Cincinnati 
Hospital  and  Professor  of  Obstetrics  at  the  Miami  Medi- 
cal College,  reported  the  obstetrical  department  for  the 
last  four  months  he  was  on  duty.     He  began  with  a  de- 
scription  of  the   obstetrical  wards,  which  showed  very 
perfect   isolation  and  care.     In   the  after  treatment  he 
spoke  of  a  ^^^  injection  of  the  bichloride  of  mercury 
twice  a  day  for   ten  days.     Pulse  and   temperature  are 
taken  twice  a  day,  and  if  any  patient  gives  evidence  of 
sepsis  she  is  taken  to  other  quarters  at  once.     During 
the  four    months  there  were  79  deliveries,  exclusive  of 
abortions  ;  42  primiparae,  37  multiparae  ;   youngest,  16  ; 
oldest,  44.     Hyperaemius  gravidorum   was   experienced 
by  47    in   the  earlier  stages  of  pregnancy,  32  escaped 
altogether.     Of  abnormal  presentations  there  occurred — 
left  occipito-posterior,  i ;  foot,  hand,  and  cord  presented 
together  in  one  instance.     The  forceps  were  used   five 
times   and  podalic   version   twice.     The    reporter  con- 
tinued with  an  extended  temperature   chart   and   brief 
reports  of  six  cases  of  difficult  labor,  two  cases  of  puer- 
peral fever,  and  one  of  scarlatina. 

Dr.  Davy  objected  to  the  use  of  injections  in  perfectly 
normal  labor,  because  unnecessary;  they  disturb  the 
parts,  and  trouble  may  ensue  from  the  contact  of  parts 
with  the  hands  of  attendants  and  the  atmosphere. 

Dr.  Stanton  thought  that  care  in  the  use  of  injections 
would  overcome  the  objections  to  them.  He  was  in 
favor  of  the  use  of  injections,  but  thought  much  of  the 
benefit  was  derived  from  the  water,  though  the  bichlor- 
ide was  not  objectionable,  and  in  some  cases  advanta- 
geous. 

The  Cincinnati  Obstetrical  Society  pursues  the  even 
tenor  of  its  way,  and  is  not  much  known  by  the  general 
public.  It  has  nearly  twenty  members,  two  of  whom  are 
of  the  gentler  sex.  The  members  meet  monthly  at  each 
other's  ofiices  or  residences. 

Our  medical  colleges  are  suffering  from  a  decrease  in 
receipts.  The  number  of  students  has  fallen  ofif  about 
thirty  per  cent,  in  each.  Cause  :  the  requirement  of 
preHminary  examination  on  entering.  This  has  relieved 
the  intestinal  tract  of  the  colleges  of  offending  material 
as  promptly  as  a  good  cathartic  usually  acts  on  the 
human  intestine.     Let  the  good  work  go  on.     Despite 


this  decrease  in  attendance  the  names  enrolled  on  the 
lists  of  private  quizzes  and  private  and  extra  courses 
has  increased,  showing  a  much  better  class  of  students 
than  formerly. 

The  Cincinnati  Hospital  has  been  noticeably  empty 
during  the  past  summer.  The  Hospital  of  the  Good 
Samaritan  has  been  in  much  the  same  condition. 

A  remarkably  interesting  case  of  rodent  ulcer  oc- 
curred at  the  St.  Mary's  Hospital  in  July  last.  It  was 
of  twenty  years'  standmg,  in  a  man  sixty-five  years  of  age, 
and  involved  the  whole  right  orbit  cheek  and  nose, 
wanting  but  three  lines  of  the  inner  angle  of  the  left  eye. 
Strange  to  say,  after  the  immense  destruction  of  tissue, 
the  patient  appeared  in  almost  perfect  health,  and  was 
always  in  good  spirits.  He  left  the  hospital  for  his  home, 
of  course  unimproved.  A  case  of  so-called  "  shaggers  " 
fever,  dengue,  **  break -bone"  fever,  was  one  of  the 
curiosities  at  the  same  hospital  during  September  last 
The  patient  had  been  working  on  the  Panama  Canal, 
and  brought  the  disease  back  with  him.  He  had  been 
sick  a  year. 

The  clinics  at  the  Good  Samaritan  and  Cincinnati 
Hospitals  have  been  very  profitable,  so  far,  this  term. 
Our  surgeons  have  been  treated  with  an  experience  in 
gunshot  injuries  recently  which  they  have  not  seen  the 
equal  of  since  the  war.  The  terrible  Court  House  riots 
of  last  March  and  the  election  riots  of  the  present  month 
furnished  them  with  about  two  hundred  gunshot  injuries. 
One  difference  the  old  surgeons  noticed  between  those 
made  by  the  militia  during  the  late  riot  and  those  made 
by  the  soldiers  of  the  late  war  is  that  the  bullets  of  the 
latter  day  do  not  stop,  but  go  clear  on  through.  I  be- 
lieve that  in  no  one  instance  in  a  wound  made  by  a 
militiaman's  bullet  in  the  riot  last  March  did  the  ball 
remain  in  the  person  wounded.  The  day  of  "  probing 
for  the  ball "  is,  it  seems,  in  reality  gone  by. 

Thirty  per  cent,  of  the  births  in  Cincinnati  are  attended 
by  midwives,  and  yet  almost  five  hundred  physicians  eke 
out  an  existence. 

Abracadabra. 

October  34,  1884. 

RECOGNITION .  OF    PRELIMINARY    WORK. 

To  TUB  Editox  or  Tub  Mbdical  Rscord. 

Sir  :  In  a  late  issue  of  The  Record,  I  observe  an 
editorial  under  the  title  :  "  Recognition  of  Hard  Pre- 
paratory Work."  From  time  to  time  criticism  of  the 
kind  you  have  made  appears  now  in  this  medical  journal, 
now  in  that;  now  in  this  form,  and  now  in  another. 
That  some  complaint  is  justified  by  the  facts  is  admitted 
by  all ;  that  the  existing  evil  should  receive  deserved 
correcting  is  the  wish  of  every  one.  Why,  then,  does  the 
evil  stand,  and  complaint  mock  itself?  Simply  because 
of  the  incompetency  of  the  means  thus  far  adopted. 

[The  writer  having  discussed  the  various  means  here- 
tofore tried  and  their  failure,  continues  :] 

The  concluding  paragraph  of  the  article  referred  to 
above  has  this  also  :  '*  Hard  preliminary  work  deserves 
a  little  recognition  other  than  the  slow  and  uncertain 
recompense  furnished  by  the  public."  Herein  is  sug- 
gested a  method  of  correction  which  most  assuredly  will 
prove  competent,  because  it  is  based  upon  the  strongest 
and  most  constant  passion  of  the  human  heart — pride. 
The  method  is  this :  Distinguish  by  some  universal  in- 
signia or  item  of  dress  the  graduate  in  medicine ;  and 
also,  by  modifications  of  this  same,  the  degree  of  pre- 
paratory education.  For  instance,  let  the  graduate  in 
medicine  be  distinguished  by  some  modest  decoration, 
or  some  suitable  device,  whatever  it  may^e,  to  be  uni- 
versally worn  and  acknowledged.  Then,  for  the  doctor 
of  medicine  who  has  been  previously  graduated  in  letters 
with  the  degree  A.B.,  an  additional  ribbon  or  another  color 
added  to  the  M.D.,  decoration  which  will  secure  the  de- 
served recognition  ;  and  so  on,  the  degrees  B.S.,  and 
A.M.  and  LL.D.,  etc.,  may  thus  receive  recognition  and 


584 


THE   MEDICAL  RECORD. 


[November  22,  1884. 


distinguish  the  '* careless  and  half-educated'*  from  those 
who  have  **  trained  themselves  thoroughly."  These 
decorations  should  be  conferred  by  the  same  authority 
and  at  the  same  time  with  the  diploma.  They  should 
mark  no  lower  course  in  letters  than  that  of  the  high 
school  or  academy,  and  the  decoration  for  this  course 
should  be  the  basis  or  ground  upon  which  the  decoration 
for  higher  courses,  B.S.,  A.B.,  A.M.,  etc.*  etc.,  are  dis- 
played. Crossing  all  these  decorations  for  literary  train- 
ing, should  be  displayed  those  of  professional  significance, 
one  for  medicine,  one  for  law,  one  for  theology,  etc. 
This  scheme  will  be  ridiculed,  I  know,  and  chiefly  by 
those  who  would  be  niaile  conspicuously  deficient  thereby. 
It  may  also  be  ridiculed  by  those  of  so  severe  taste  as  to 
be  offended  by  anything  that  in  any  way  distinguishes. 
It  may  also  be  opposed  by  some  as  altogether  "  too 
silly,"  etc.,  etc.  However,  to  the  first  I  would  say,  your 
opposition  is  its  very  best  argument ;  to  the  second,  it 
is  not  at  all  a  question  of  individual  likes  and  preferences; 
to  the  third,  what  one  among  you  would  decline  the  red 
ribbon  of  the  Legion  of  Honor  if  it  were  oflfcred  ? 

J.  D.  Kelly,  M.D. 

Utica,  N.  Y. 

PROTRACTED   PREGNANCY. 

To  TUB  Editok  or  Thb  Mkdical  Rrcord. 

Sir  :  I  wish  to  put  on  record  a  protracted  pregnancy. 

The  case  referred  to  is  Mrs.   P ,  aged  thirty-two ; 

Irish-American ;  medium-sized.  This  was  her  fourth  child. 
The  third  was  bom  November  24,  1882.  She  menstruated 
regularly  from  the  time  she  began  after  the  birth  of  her 
third  child  until  September  22,  1883,  on  which  date  the 
menstrual  flow  began  and  continued  in  the  usual  manner 
until  September  25th.  That  was  the  last  time  she  men- 
struated until  she  was  delivered  of  a  healthy  living  child 
(male)  weighing  eleven  and  a  half  pounds  on  August  21, 
1884,  in  the  evening.  The  time  of  parturition  was  about 
three  hours. 

The  duration  of  pregnancy  was  just  three  hundred  and 
thirty  days.  The  above  dates  I  can  vouch  for,  for  the 
following  reason  :  The  woman  was  desirous  of  not  having 
more  children,  and  kept  on  a  calendar  the  dates  of  her 
menstruation,  and  had  not  passed  her  period  but  a  few 
days  before  she  came  to  me  to  see  if  something  could 
not  be  done. 

The  longest  case  I  can  find  on  record  is  from  Leish- 
man's  "Midwifery,*'  page  175,  where  the  duration  was 
three  hundred  and  twenty-two  days.  Professor  Atlee  re- 
cords several  of  one  yearns  duration,  I  believe,  but  I 
never  have  seen  the  records  myself. 

Yours  truly, 

J.  W.  Wright,  M.D. 


THE  MORAL  EFFECT  OF  MEDICAL  EDUCA- 
TION  ABROAD. 

To  THK  Editor  of  Thb  Mbdical  Rbcord. 

Sir  :  With  regard  to  the  **  demoralizing  influence "  of 
medical  education  abroad  I  must  say  that,  whatever  may 
be  the  case  in  the  continental  cities,  the  statements  made 
can  in  no  way  be  applied  to  the  London  schools.  By 
no  means  the  least  of  the  advantages  of  a  London  educa- 
tion, especially  to  a  young  man,  is  the  high  moral  tone 
that  pervades  the  profession,  and  the  refining  influence 
that  intimate  association  with  men  of  as  high  character 
as  the  London  teachers  are,  must  necessarily  impart. 
I  think  I  can  speak  without  bias  on  the  subject,  being  a 
graduate  of  two  prominent  universities  in  this  country, 
and  having  subsequently  passed  through  the  entire  cur- 
riculum at  a  London  school  of  medicine.  And  I  venture 
the  assertion  that  the  moral  atmosphere  of  the  lecture 
rooms,  dissecting  halls,  and  hospitals  in  London  compare 
most  favorably  with  any  in  this  country  or  elsewhere. 
Any  one  who  has  had  more  than  a  casual  view  of  the 
working  of  a  London  hospital  and  of  the  deportment  of 


its  attaches  cannot  fail  to  have  noticed  that  the  welfare 
of  the  patients  is  the  prime  object  with  all  concerned, 
and  that  in  no  place  is  woman  held  in  greater  respect  or 
treated  with  greater  delicacy  and  consideration. 
I  am,  sir,  very  truly  yours, 
Thomas  Greaves,  M.D.,  M.R.C.S.,  Etc, 

Adjunct  Professor  of  Medicine^  Medical  ColUg*  of  Virfuiia. 


"  CONGENITAL  HAEMORRHOIDS." 

To  the  Editor  of  The  Medical  Rbcokd. 

Sir  :  I  have  a  curious  lusus  natunz  here  in  Brooklyn. 
A  baby,  female,  was  born  October  2  2d,  of  healthy 
American  parents,  aged  twenty-nine  and  twentyfour 
years  respectively,  bemg  the  first  child.  The  mother  has 
always  been  the  picture  of  health,  excepting  chronic 
constipation  and  its  natural  result,  haemorrhoids,  which 
have  been  many  years  a  torment  to  her,  and  were  natu- 
rally extremely  aggravated  by  pregnancy. 

At  birth  the  little  girl,  otherwise  well  formed,  presented, 
at  the  verge  of  the  anus,  on  the  right  side,  a  fold  of  skin 
projecting  three  to  four  millimetres  from  the  normal 
level  of  epidermis  and  five  millimetres  long  by  three 
millimetres  broad.  This  is  cpvered  with  healthy,  normal 
integument,  of  natural  color  and  sensibility.  It  is,  then, 
an  imitation  of  a  pile,  just  where  the  mother's  most  an- 
noying tumor  was  located.  The  little  tumor  seems  to  be 
merely  an  excess  of  skin  at  that  point,  and  is  in  color 
and  texture  so  like  healthy  skin  as  to  show  that  it  cannot 
be  the  result  of  inflammation. 

The  mother  was  very  anxious  to  know  if  her  baby 
''had  piles,"  as  she  had  suffered  so  much  herself,  and 
said  ''  she  had  been  praying  for  months  that  her  child 
might  be  spared  an  affliction  which  had  caused  its  mother 
so  much  suffering."     Is  this  z.post  hoc  or  z,  propter  hod 

Certainly  the  mother  directed  her  thoughts  continu- 
ously for  many  days  at  a  time  toward  this  spot  on  her  baby. 

Is  a  similar  case  reported  ?     Yours, 

A.  B.  DE  S.  SiZER,  M.D. 

Brooklyn,  N.  V.,  October  30,  1884. 


THE  AMERICAN  MODE    OF    GIVING    POTAS- 
SIUM  IODIDE. 

To  THB  Editor  of  The  NIbdical  Record. 

In  your  editorial  of  November  i,  in  the  article  headed 
"  American  Mode  of  Using  Iodide  of  Potassium,"  you 
state,  "The  writer  also  shows  that  the  method  originated 
with  the  late  Dr.  Van  Buren  of  this  city,  and  became 
gradually  adopted  as  the  result  of  practical  experience  by 
a  number  of  New  York  physicians.  .  .  .  It  is  essen- 
tially an  American,  and  more  essentially  a  New  York 
idea."  I  beg  to  inclose  a  copy  of  a  prescription  I  gave 
in  a  case  of  syphilis  in  July,  1859  : 

5.  Potassii  iodidi 3  vj. 

Ext.  sarsae  fluid 5  U- 

Mucilag.  acacise |  iv. 

M.  Two  tablespoonfuls  four  times  daily,  to  be  fol- 
lowed by  a  tumbler  of  flax-seed  tea. 

This  prescription  bears  the  date  (as  copied  from  my 
note-book)  of  July  26,  1859. 

It  will  thus  be  seen  that  the  method  of  giving  iodide 
of  potassium  in  large  doses  is  by  no  means  a  New  York 
method,  but  was  used  in  New  Orleans  twenty-five  years 
ago. 

As  I  had  only  been  in  this  country  about  five  years  at 
that  time,  it  might  more  correctly  be  termed  an  English 
method.  I  do  not  claim  any  especial  credit  for  giving 
the  remedy  in  these  doses,  but,  if  there  be  any  it  should 
certainly  be  given  to  the  one  who  originated  it. 

J.  L.  Crawcour,  M.D.,  M.R.C.S.,  Eng. 

Z94  Camp  Street, 
New  Orleans,  La^  November  4,  1884. 

P.S. — I  would  State  that  the  above  prescription,  with 
some    trifling    modifications,  was    persevered  in   until 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


58s 


August  iTth,  when  it  was  given  in  gradually  diminishing 
doses.  The  result  was  an  absolute  cure,  the  patient 
remaining  under  my  observation  for  twenty  years  without 
any  recurrence  of  the  disease. 

[Many  physicians  have  doubtless  given  large  doses  of 
iodide  of  potassium.  The  merit  of  doing  this  systemati- 
cally, of  recognizing  and  teaching  it  as  producing  specific 
therapeutical  effects,  belongs,  so  far  as  we  yet  can  learn, 
to  New  York  physicians.] 


"^exo  %nstvximc\its. 


A  CORRECTED   DESCRIPTION  OF  THE  CON- 
TINUOUS   INDUCTION   COIL. 

With  an  Illustration. 

By  a.  D.  ROCKWELL,  M.D., 

NBW  VOBK. 

The  accompanying  diagram  is  here  presented  and  de- 
scribed as  it  should  have  been  in  my  article  on  *'  The 
Induction  Coil :  Its  Varieties,  and  the  Differential  In- 
dications for  their  Use,"  which  appeared  in  this  journal, 
November  8,  1884. 

**  These  coils  are,  for  convenience  of  illustration,  rep- 
resented by  the  upper  straight  lines  I,  II,  III,  IV, 
termed,  respectively,  the  primary,  first,  second,  and  third 
induction  coils.  The  letters  A,  B>  C,  D,  E  represent  the 
different  posts  of  the  continuous  coil  apparatus  to  which 
the  conducting  cords  are  attached,  while  the  numerals  i, 
2,  3,  4,  etc.,  indicate  the  combinations  by  which  are  ob- 
tained ten  different  qualities  of  current.  The  short  line 
marked  i,  starting  from  A,  represents  the  current  from 
the  short,  thick,  primary  coil  marked  I.  Second  line 
(2),  current  from  the  primary  and  first  (I,  II)  induction 
coils  combined.  Third  line  (3),  current  from  the  primary 
and  first  and  second  (I,  II,  III)  induction  coils.  Fourth 
line  (4),  current  from  primary,  first,  second,  and  third 


Assigned  to  duty  as  Post-Surgeon  at  Fort  Wingate,  N.  M. 
S.  O.  217,  Department  of  Missouri,  November  4,  1884. 

Owen,  Jr.,  Willlam  O.,  First  Lieutenant  and  Assist- 
ant Surgeon.  Relieved  from  duty  at  Fort  Canby,  W.T.* 
and  ordered  to  Fort  Spokane,  W.  T.,  for  duty.  S.  0. 169, 
Department  of  Colorado,  November  4,  1884. 

Qficiai  List  of  Changes  in  the  Medical  Corps  of  the  U.  S. 
Navy^  during  the  week  ending  November  15, 1884. 

Beardsley,  Grove  S.  Promoted  to  the  grade  of  Medi- 
cal Inspector.     April  24,  1884.     November  14,  1884. 

Heffenger,  A.  C,  Passed  Assistant  Surgeon.  Duty 
at  Portsmouth,  N.  H.,  continued  till  December  12,  1885. 
November  11,  1884. 

Wieber,  F.  W.  F.,  Assistant  Surgeon.  To  the  receiv- 
ing ship  Vermont,  at  New  York.     November  12,  1884. 

Contagious  Diseases — Weekly  Statement. — ^Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  November  15,  1884 : 


Week  Ending 


Casu, 

November  8, 1884. . 
November  15,  1884. 


Deaths. 
November  8,  1884. . 
November  15,  1884. 


ft 


f 


107 


I      11 


III 


(I,  II,  III,  IV)  induction  coils.  Fifth  line  (5),  current 
from  the  first  (II)  induction  coil  only.  Sixth  line  (6), 
current  from  the  ^st  and  second  (II,  III)  induction 
coils.  Seventh  line  (7),  current  from  the  first,  second, 
and  third  (II,  III,  IV)  induction  coils.  Eighth  line  (8), 
current  from  the  second  (III)  induction  coiL  Ninth 
line  (9),  current  from  the  second  and  third  (III,  IV)  in- 
duction coils  combined.  Tenth  line  (10),  current  from 
the  third  (IV)  induction  coil  only." 

OfficiallMtof  Changes  in  the  Stations  andDuHes  of  Officers 
serving  in  the  Medical  Department^  United  States  Army, 
from  JVovember  9  to  November  15,  1884. 

Byrn£,  C.  C,  Major  and  Surgeon.  Granted  four 
months  leave  of  absence  from  November  16,  1884.  S. 
O.  265,  A.  G.  O.,  November  11,  1884. 

Tremaine,  W.  S.,  Major  and  Surgeon.  Granted 
leave  of  absence  for  one  month  on  surgeon's  certifi- 
cate of  disability.  S.  O.  233,  Department  of  the  East, 
November  12,  1884. 

Wilson,  William  J.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  four  months,  with  permis- 
sion to  go  beyond  sea.     S.  O.  262,  A.  G.  O.,  Nov.  7,  1884. 

Shufsldt,  R.  W.,   Captain   and  Assistant-Surgeon. 


Opium  in  Mitral  Insufficiency,  with  an  Ethical 
Episode. — ^T'he  fact   that  opium  (in  small  doses)  has 

been  frequently 
IV  recommended 

1  of  late    as   a 

I  heart      tonic, 

j  makes  the  fol 

!  lowing  case,  as 

-;  well  as  that  of 
*  Dr.  Edson,  of 
especial  inter- 
est. Dr.  George  T.  ^TcCoy,  of  Columbus,  O.,  writes 
that  he  was  called  in  to  see  a  man,  aged  sixty-one,  who 
was  suffering  from  congestion  of  the  lungs,  with  a 
troublesome  cough  and  severe  attacks  of  dyspnoea  at 
night.  Five  grains  of  Dover's  powder  at  night  caused  an 
alarming  attack  of  dyspnoea.  *  Dr.  McCoy  then  found 
that  the  patient  had  mitral  insufficiency  and  a  dilated 
heart.      D3/spnoea  and  insomnia  continued,  and  a  Dr. 

L was  called  in  consultation.     Our  correspondent 

says  :  "I  received  a  note  shortly  after  Dr.  L ^'s  visit, 

informing  me  that  that  gentleman  (?)  had  assumed  charge 
of  the  case,  and  my  services  were  no  longer  needed. 

Dr.  L went  to  work   to  •  give  his  patient   rest,'  *  he 

was  simply  dying  for  want  of  rest-'  Administered  tr. 
opii,  gtt.  XXV.,  every  three  hours  until  patient  was  able 
to  go  to  sleep.  Patient  made  two  attempts  to  lie  down, 
but  the  dyspnoea  was  so  aggravated  by  change  of  posture 
that  he  was  fain  to  be  propped  up  in  a  chair  again.  After 
taking  one  full  dose,  and  at  the  third  hour  half  the  quan- 
tity (in  all  thirty-five  drops)  he  was  enabled  to  sleep 
very  quietly  about  four  hours,  when  his  breathing  became 
labored,  and  death  ensued  without  his  return  to  con- 
sciousness again.     The  death  was  reported  by  Dr.  L 

at  the  Health  Office,  as  due  to  *  acute  congestion  of  the 
lungs."  My  opinion  then,  as  now,  was  paralysis  of  the 
heart  due  to  opium-poisoning.  I  am  led  to  make  this 
report  by  perusing  the  article  of  Dr.  Edson,  in  a  recent 
number  of  The    Record,   the    cases  being  so  nearly 


586 


THE   MEDICAL  RECORD. 


[November  22,  1884. 


alike  in  everything  except    the  position  of  the  patient 
preceding  death." 

[It  is  unfortunate  that  an  autopsy  was  not  obtained  in 
order  to  verify  the  diagnosis.  Not  unlikely  there  was 
some  condition  other  than  those  discovered  by  Dr. 
McCoy.  The  best  and  latest  authorities — Bramwell, 
Allbutt,  Sansom,  and  others — in  the  continuous  dyspnoea^ 
orthopncea,  and  insomnia  of  uncompensated  mitral  insuf- 
ficiency.— Ed.] 

Accommodation  and  Presbyopia. — M.  Martialis,  who 
is  presbyopic,  resorts  to  the  following  manoeuvre  when  he 
is  without  his  glasses  and  wishes  to  read  :  He  introduces 
the  pulp  of  thcf  index  finger  rather  deeply  between  the 
external  border  of  the  orbit  and  the  globe  of  the  eye  on 
that  part  covered  by  the  upper  lid,  making  somewhat 
firm  pressure.  He  states  that  the  characters  then  be- 
come visible  and  he  is  able  to  read  with  ease.  M.  Mar- 
tialis thinks  that  this  would  be  useful  in  the  diagnosis 
between  a  simple  presbyopia  and  paralysis  of  the  retina, 
crystalline  opacity,  etc.  He  sees  in  this  a  proof  of  the 
r61e  played  by  the  straight  and  oblique  muscles  in  the 
function  of  accommodation. — Lyon  Mhiical^  October  5, 
1884. 

In  Dr.  Millard's  letter,  in  our  issue  of  November 
8th,  on  the  Prevalence  of  Consumption  at  Various  Ages, 
page  528,  seventh  line  from  the  top,  27,771,728  should 
read:  2,771,728. 

The  Responsibility  of  Physicians  for  Furnishing 
Proper  Certificates  of  Insanity  in  cases  before  them 
is  a  matter  of  great  importance,  considering  the  rapidly 
increasing  number  of  instances  where  the  services  of  a 
skilled  physician  are  called  for.  In  a  recent  case  in  a 
New  England  State  the  action  was  brought  for  damages 
against  a  physician  for  falsely  certifying,  through  malice 
or  negligence,  that  a  person  was  insane,  and  thereby  ac- 
complishing her  commitment  to  an  insane  asylum.  The 
pleadings  in  the  suit  raised  the  question  as  to  the  actual 
condition  of  the  person  at  the  time  she  was  declared  to 
be  insane,  and  as  the  presumption  was  in  favor  of  the 
certificate  being  correct,  the  burden  of  proof  was  upon 
the  persons  alleging  that  she  was  sane.  The  court  said  : 
**  In  such  an  action  the  falsehood,  and  not  the  insufiiciency 
of  the  certificate,  is  the  ground  of  action  against  the 
certifying  physicians.  Without  statutory  provisions  to 
that  effect  there  cannot  be  a  civil  action  for  damages 
against  a  physician  based  upon  the  insufficiency  of  the 
methods  which  he  pursued  in  reaching  and  certifying  a 
correct  conclusion.  In  such  an  action  it  is  open  to  the 
defendants  to  prove  precisely  what  were  the  circum- 
stances under  which  they  acted,  what  inquiry,  investiga- 
tion, and  examination  they  made,  and  what  the  informa- 
tion was  on  which  they  proceeded.  If  such  testimony 
did  not  go  to  the  extent  of  a  justification  in  case  their 
certificates  should  be  found  to  be  false  on  the  question 
of  insanity,  it  was  proper  evidence  to  be  considered  in 
awarding  damages.  If  physicians  who  have  certified  to 
the  insanity  of  a  person,  have  not  made  the  inquiry  and 
examination  which  the  statute  requires,  or  if  their  evi- 
dence and  certificate  in  any  respect  of  form  or  substance 
is  not  sufficient  to  justify  a  commitment,  the  municipal 
officers  should  not  commit,  and  if  they  do,  it  is  their  fault 
and  not  that  of  the  physicians,  provided  they  have  stated 
facts  and  opinions  truly,  and  have  acted  with  due  profes- 
sional skill  and  care." 

Professional  Dignity  and  What  Sometimes  Comes 
OF  IT.—Our  London  Correspondent  sends  us  the  following: 
"  Many  doctors  are  very  fond  of  talking  about  the  dig- 
nity of  the  profession,  and  how  we  should  all  of  us  do  our 
best  to  uphold  it.  An  eminent  London  physician  once  told 
me,  in  conversation,  that  he  makes  a  point  of  never  thank- 
ing his  patients  for  his  fee  when  he  takes  it,  but  simply 
pockets  it  as  a  matter  of  course  as  his  due.  I  presume 
he  would  similarly  disdain  to  ask  for  it  should  the  patient 
depart  without  offering  to  pay.  They  sometimes  do  this. 
A  friend  of  the  writer's  who  was  once  treated  thus  by  a 


lady  richly  attired,  stopped  her  just  as  she  was  making 
her  exit,  and  in  the  blandest  of  terms  begged  to  be  allowed 
to  look  at  the  prescription  again  for  a  moment.  He 
looked  at  it  for  a  few  seconds,  and  then,  tearing  it  across, 
threw  it  into  the  fire.  *  Ladies  in  silks  and  satins,'  he 
said,  *  can  generally  afford  to  pay,*  and  calmly  rang  his 
bell  for  his  servant  to  usher  in  the  next  patient.  Doctors 
occasionally  get  the  worst  of  it  though,  when  they  stand 
too  much  on  their  dignity  with  patients.  One  of  the 
local  practitioners  in  a  country  town  I  have  frequently 
visited,  was  one  day  sent  for  to  visit  a  child  in  the  family 
of  one  of  his  patients.  On  arrival  he  found  his  little 
patient  had  been  ailing  for  some  days,  and  asked  why  he 
had  not  been  called  in  before.  •  Oh,'  said  the  mother, 
*  we  have  been  giving  it  a  bottle  of  E 's  stuffi'  mention- 
ing a  patent  medicine  prepared  by  a  veterinary  surgeon 
well  known  in  the  county,  and  a  bottle  of  which  she  had 
obtained  at  the  chemist's.  *  What  1  *  exclaimed  the  doc 
tor,  *  expect  me  to  attend  after  a  horse-doctor  ?  '  and  he 
marched  off  in  great  indignation.  The  father  of  the 
child  was  a  baker,  and  supplied  the  doctor's  family  with 
bread.  Next  day  no  bread  was  delivered  at  the  doctor's 
house.  The  doctor's  wife  put  on  her  bonnet  and  shawl 
and  went  out  to  call  on  the  baker,  respecting  the  omis- 
sion. On  entering  the  shop  she  saw  the  baker's  better 
half,  and  politely  intimated  that  she  had  called  to  say  that 
no  bread  had  been  left  as  usual,  and  she  would  be  glad  to 
have  some  sent.  *  Oh,  no,'  was  the  reply,  'your husband 
won't  attend  us  as  a  doctor,  so  we  shan't  supply  him  with 
bread,'  and  they  didn't  The  doctor  was  forced  to  deal 
with  another  and  inferior  baker,  as  similarly  the  baker  had 
on  the  previous  day  been  forced  to  send  for  another  doc- 
tor. By  the  time  this  appears  in  your  pages  medical 
students  and  professors  alike  will  be  preparing  for  the 
opening  of  the  winter  session,  which  is  always  heralded 
by  the  first  of  October.  The  Scotch  schools  do  not  begin 
till  the  first  of  November.  It  seems  a  pity  in  each  case 
that  the  studies  could  not  be  so  arranged  as  to  give  more 
summer  holiday,  say  by  beginning  in  the  middle  of  Septem- 
ber and  continuing  until  the  first  week  in  July,  with  only 
fortnightly  vacations  at  Christmas  and  Easter,  instead  of 
having  April  as  an  idle  month,  and  sweltering  in  town  till 
the  last  week  in  July.  Some  of  the  medical  examinations 
are  even  held  during  August." 

The  Cost  of  Sickness. — I  think,  then,  that  we  can- 
not escape  from  the  reasons  to  believe  that  we  lose  in 
England  and  Wales  every  year,  in  consequence  of  sick- 
ness, 20,000,000  weeks'  work ;  or  say,  as  much  work  as 
20,000,000  healthy  people  would  do  in  a  week.  The 
number  is  not  easily  grasped  by  the  mind.  It  is 
equal  to  about  one-fortieth  part  of  the  work  done  in  each 
year  by  the  whole  population  between  fifteen  and  sixty- 
five  years  old.  Or,  try  to  think  of  it  in  money.  Rather 
more  than  half  of  it  is  lost  by  those  whom  the  Registrar- 
General  names  the  domestic,  the  agricultural,  and  the 
industrial  classes.  These  are  more  than  7,500,000  in 
number,  and  they  lose  about  1 1,000,000  weeks  ;  say 
for  easy  reckoning,  at  ;^i  a  week  ;  and  here  is  a  loss  of 
;^ 1 1,000,000  sterling  from  what  should  be  the  annual 
wealth  of  the  country.  For  the  other  classes,  who  are 
estimated  as  losing  the  other  9,000,000  weeks'  work,  it 
would  be  hard  and  unfair  to  make  a  guess  in  any  known 
coin  ;  for  these  include  our  great  merchants,  our  judges 
and  lawyers,  and  medical  men,  our  statesmen  and  chief 
legislators ;  they  include  our  poets  and  writers  of  all 
kinds,  musicians,  painters,  and  philosophers  ;  and  our 
princes,  who  certainly  do  more  for  the  wealth  and  wel- 
fare of  the  country  than  can  be  told  in  money. — Sir  James 
Paget 

Value  of  Veratrum  Viride  as  a  Prophylactic 
AGAINST  Peritonitis  after  Surgical  Operations  in- 
voLviNG  the  Opening  of  the  Peritoneal  Cavity. — 
Dr.  James  Roane,  of  Yankton,  Dak.,  writes :  "  On 
August  25  th,  assisted  by  Drs.  D.  F.  Etter,  and  W.  H. 
Turkopp,  I  operated  upon  R.  S ,  a  short  and  spare 


November  22,  1884.] 


THE  MEDICAL  RECORD. 


587 


Bohemian,  aged  fifty-five,  for  the  relief  of  strangulated 
hernia  (right,  complete  oblique  inguinal).  A  careful  and 
thorough  trial  of  the  taxis,  at  first  without  the  aid  of 
anaesthetics,  and  subsequently  when  they  were  admin- 
istered to  the  surgical  extent,  had  failed  to  produce  re- 
duction. Owing  to  the  urgency  of  the  symptoms,  the 
operation  was  performed  at  night,  and  was  more  pro- 
tracted than  it  would  otherwise  have  been  on  account  of 
the  very  poor  light  of  a  single  lamp.  The  intestine  was 
found  to  be  deeply  congested,  but  showed  no  signs  of 
disorganization.  The  constriction  was  at  the  internal 
ring,  and  its  division  was  followed  by  the  escape  of  about 
two  ounces  of  sanguineous  serum.  The  hernia  having 
been  reduced,  the  upper  three-fourths  of  the  incision 
were  closed  by  sutiures,  and  the  lower  fourth  left  open 
for  drainage.  Throughout  its  various  steps  the  operation 
was  conducted  under  strictly  antiseptic  precautions — a 
solution  of  corrosive  sublimate,  one  to  two  thousand,  be- 
ing used  for  that  purpose.  A  pledget  of  absorbent  cotton, 
soaked  in  this  solution,  was  placed  over  the  wound ;  this 
was  covered  by  a  larger  pad  of  cotton,  and  the  whole  was 
held  securely  in  situ  by  a  few  turns  of  a  roller  bandage. 
On  coming  from  under  the  influence  of  the  anaesthetic 
the  patient  vomited  stercoraceous  matter  profusely.  He 
was  put  to  bed,  given  one-fourth  of  a  grain  of  morphia 
hypodermically,  and  placed  upon  one  minim  of  Nor- 
wood's tincture  of  veratrum  viride,  and  ten  minims  of 
deodorized  tincture  of  opium,  every  two  hours — day  and 
night.  This  treatment  was  followed  up  to  the  morning 
of  the  28th,  when  it  was  discontinued  because  of  the  fall 
of  the  temperature,  the  total  absence  of  any  of  the  signs 
of  peritonitis,  and  the  increasing  prostration  of  the  pa- 
tient The  physiological  action  of  the  veratrum  viride  at 
this  time  was  very  marked,  manifesting  itself  in  the  sense 
of  extreme  muscular  weakness,  and  in  the  slow,  moder- 
ately full,  but  soft  pulse,  which  became  very  rapid  on  the 
patient's  making  the  least  exertion.  At  no  time  after 
the  operation  were  there  any  of  the  local  signs  of  peri- 
tonitis, such  as  pain,  tenderness,  or  tympanitis.  The 
highest  temperature  (taken  under  the  tongue)  was  ioo.8°; 
and  this  occurred  on  the  evening  of  the  26th.  On  the 
29th  the  temperature  was  normal,  and  subsequently  it 
did  not  rise  above  99°.  In  that  portion  of  the  incision 
which  was  closed  by  means  of  sutures,  union  took  place 
by  first  intention.  A  slight  serous  discharge  oozed  from 
the  lower  fourth,  left  open  for  drainage  for  forty  hours, 
but  thereafter  no  stains  could  be  detected  on  the  cotton 
dressing,  and  the  wound  rapidly  closed.  On  September 
9th  a  well-fitting  truss  was  applied,  and  the  patient  dis- 
charged. 

The  Modern  Iter  ad  Astra — ^a  Medical  Fable, 
— Once  upon  a  time  a  poor  but  humane  physician  was 
riding  along  a  road  which  led  by  a  dark  forest,  when  he 
saw  by  the  wayside  a  sick  and  miserable  dog  which  had 
lain  down  to  die.  Moved  with  pity  he  got  down  from 
his  carriage,  picked  up  the  poor  animal  tenderly,  and 
gave  it  some  food  and  drink.  Suddenly  the  dog  van- 
ished, and  he  saw  standing  before  him  a  beautiful  fairy. 

"  You  have  saved  me  from  a  miserable  doom  by  your 
compassion,"  she  said.  "  Command  now  anything  you 
wish,  and  it  shall  be  yours." 

The  astonished  physician  replied,  ''  I  am  a  poor  man. 
I  should  like  to  be  rich." 

The  fairy  waved  her  wand,  and  extended  to  him  a 
piece  of  paper  and  a  bottle  filled  with  a  dark-colored 
fluid.  "  Here,"  she  said,  "  is  a  prescription  for  an  In- 
fallible Compound  Hair-Restorer.  It  will  never  fail, 
and  it  has  been  indorsed  by  all  the  leading  clergymen  on 
both  continents.  The  world  is  yours  !  Do  you  wish 
more  ?  " 

"  I  am  a  quiet  man,"  replied  the  doctor,  "  and  little 
known.     I  should  like  to  be  famous." 

"  You  shall  be  more  ;  you  shall  be  immortal."     Wav- 

I  ing  her  wand  again,  she  presented  to  him  a  small,  dark, 

and  curiously  shaped  instrument.     "  See,"  she  exclaimed, 

"it  is  a  new  and  *  Unquestionably  Perfect  Pessary.'     It 


radically  restores  every  malposition.  Your  name  is 
blown  into  the  side.  Generations  of  suffering  women 
and  successful  doctors  will  read,  and  bless  you.  I  have 
tried  it  myself,"  she  added,  blushing  a  little,  and  van- 
ished.— Boston  Med,  and  Surg,  Journal, 

Renal  Calculi  and  their  Removal  by  Manipula- 
tion.— Dr.  J.  P.  Shafer,  of  Parkersburg,  VV.  Va.,  sends 
us  the  history  of  a  patient,  a  married  lady,  thirty-four 
years  of  age,  who  for  two  years  suffered  greatly  from 
pains  in  the  back,  left  iliac  region  and  hip,  and  retention 
of  urine.  This  finally  culminated  in  hip-joint  disease, 
an  abscess  breaking  into  the  vagina,  the  left  limb  being 
shortened  one  and  a  half  inch.  She  had  also  cystitis, 
and  later  some  hysterical  symptoms.  In  the  course  of  a 
year  she  developed  violent  symptoms  of  renal  colic  on 
the  left  side.  She  passed  gravel  in  the  urine.  Feeling 
sure  that  she  was  passing  calculi  through  the  ureters.  Dr. 
Shafer  conceived  the  highly  novel  plan  of  helping  them 
along  by  manipulation.  He  describes  this  in  the  follow- 
ing language :  "  The  patient  being  placed  upon  her 
stomach,  so  that  I  could  get  with  my  fingers  down  upon 
the  kidney,  by  firm  pressure,  working  my  fingers,  press- 
ing and  pulling  toward  me,  I  soon  found  I  had  changed 
the  seat  of  pain  to  another  point  a  little  forward,  which 
she  could  locate  by  the  touch  of  her  finger  over  the  lo- 
cation of  the  stone,  and  so  I  continued  this  manipulation 
at  intervals,  removing  each  time  the  stone  several  inches 
before  stopping  to  rest  again,  and  each  time  before  again 
commencing  she  would  locate  the  point  at  which  the 
stone  was,  and  so  I  proceeded  until  I  felt,  as  well  as  she, 
it  pass  from  under  my  fingers,  as  I  supposed,  into  the 
bladder,  and  which  afterward  proved  to  be  true.  As 
soon  as  it  passed  into  the  bladder  the  agonizing  pain  and 
muscular  spasms  ceased  at  once  and  the  patient  became 
cheerful.  She  being  relieved  for  the  time  was  happy, 
and  I  having  performed  this  feat,  the  like  of  which  I  had 
never  read,  heard,  nor  dreamed  of  before,  of  course  I 
was  quite  well  pleased  at  my  success."  From  this  time 
forward,  for  the  next  ten  days,  she  passed  calculi  every 
day,  the  passage  being  assisted  by  Dr.  Shafer.  Then  she 
passed  no  more  for  fourteen  months,  when  the  attacks 
began  again  and  continued  in  the  same  way  and  with  the 
same  treatment.  Dr.  Shafer  secured  some  of  the  calculi, 
one  of  which,  he  says,  measures  one  to  one  and  one-eighth 
inch  in  length,  by  one-half  to  three-eighths  inch  in 
width.  He  states  that  he  forwards  to  us  some  speci- 
mens. We  have  not,  however,  received  them.  The  pa- 
tient is  still  living,  and  has  been  seen  and  manipulated 
by  other  physicians.  Our  correspondent  says  truly  that 
the  case  is  a  very  extraordinary  one.  The  fact  that  the 
woman  is  hysterical,  suggests  the  probability  of  some 
voluntary  or  involuntary  deception. 

Acute  Iodism  after  Three  Five-grain  Doses  of 
Potassium  Iodide. — J.  B.  Parker,  M.D.,  Surgeon  U.S. N., 
writes :  "  Extracted  (torn  Journal  de  Medecine  et  de  Chirur- 
gie  Pratiques,  in  The  Record  of  the  6th  ult,  is  men- 
tion of  a  case  of  acute  iodism  after  a  smgle  dose  of  fifteen 
grains  of  iodide  of  potassium.  I  beg  to  present  the  fol- 
lowing case,  as  probably  equally  severe,  after  the  admin- 
istration of  the  same  quantity  of  iodide  of  potassium  in 
three  five-grain  doses — ^morning,  noon,  and  night.  Pa-* 
tient,  aged  forty,  a  man  of  superior  physique  and  health, 
had  acute  rheumatism  in  right  shoulder.  The  first  even- 
ing he  came  under  observation  one-sixth  grain  of  mor- 
phia sulph.  was  administered  hypodermically,  after  local 
dressing  with  warm  laudanum,  flannel,  cotton,  and  rubb'er 
cloth.  Following  day  patient  was  given  ten  grains  of 
bromide  of  potassium,  p.  r.  n.,  to  relieve  pain  and  induce 
sleep.  This  failing  to  afford  the  relief  desired  at  night, 
it  was  discontinued,  and  a  solution  of  bromides  of  potas- 
sium and  sodium,  of  each  ten  grains,  and  of  lithium  five 
grains,  was  directed  to  be  taken  during  the  day  if  re- 
quired, and  hourly  at  night  if  pain  prevented  sleep.  The 
succeeding  day  (fourth)  no  medicine  was  taken  save  three 
or  four  doses  at  night  of  the  bromide  mixture,  as  was 


[ 


588 


THE   MEDICAL  RECORD. 


[November  22,  1884. 


taken  during  the  previous  night.  The  acute  symptoms 
having  in  great  part  subsided,  he  was  directed,  for  the 
fifth  day,  five  grains  of  iodide  of  potassium  morning, 
noon,  and  night.  On  the  sixth  day  patient  suffered 
severely  from  iodism,  which  he  ascribed  to  taking  cold 
during  the  night,  yet  was  much  puzzled  to  explain  its 
origin,  as  he  had  not  left  his  bed  and  was  not  aware  that 
a  current  of  air  could  reach  him.  When  the  real  cause 
of  his  suffering  was  mentioned  he  remarked  that  the 
remedy  was  as  severe  as  the  disease  and  preferred  not  to 
continue  it  The  symptoms,  which  disappeared  in 
twenty-four  hours  when  the  medicine  was  discontinued, 
were  as  follows  :  Pain  and  constriction  in  region  of  fron- 
tal sinuses ;  pufHness  and  suffusion  of  eyes,  with  lachry- 
mation ;  sneezing  and  secretion  from  nose  ;  soreness  of 
jaws  and  mucous  membrane  of  mouth  and  throat ;  ptyal- 
ism ;  cervical  glands  on  left  side  enlarged  and  painful ; 
small  but  painful  abscess  on  helix  of  left  ear, .  which 
suppurated  and  was  discharged.'' 

A  Breach  of  Professional  Etiquette. — The  fol- 
lowing story  is  told  of  the  celebrated  Oppolzer.  Shortly 
after  his  arrival  in  Vienna  he  was  consulted  by  an  invalid, 
whom  he  advised,  after  a  somewhat  hasty  examination, 
to  go  to  Pistyan,  in  Hungary,  and  take  the  waters.  After 
several  months  the  man,  whom  the  professor  had  for- 
gotten, again  presented  himself,  with  an  aggravation  of 
all  his  symptoms,  and  said  he  had  just  returned  from  a 
course  of  the  Pistyan  waters.  The  professor  examined 
him,  this  time  rather  more  carefully,  and  then,  with  some 
wrath,  asked  him  what  confounded  ass  had  advised  him 
to  go  there,  as  it  was  the  worst  thing  he  could  possibly 
have  done.    Moral :  Always  speak  well  of  your  neighbor. 

Whiskey  as  an  ANiESTHETic. — In  his  address  as  Presi- 
dent of  the  Ninth  Annual  Session  of  the  Arkansas  State 
Medical  Society,  Dr.  Keller  is  reported  to  have  spoken 
as  follows  on  the  subject  of  whiskey  as  an  anaesthetic : 
•*  To  Dr.  Link,  of  Indiana,  are  we  indebted  almost  en- 
tirely for  having  gone  far  toward  placing  whiskey  not  only 
along  with  ether  and  chloroform  as  an  anaesthetic,  but 
also  in  discovering  its  antiseptic  power,  equally  as  safe 
and  effective  as  any  other.  So  well  satisfied  is  that  gen- 
tleman from  long  use  of  it  as  his  only  anaesthetic  and 
antiseptic  in  amputations,  that  he  asserts  he  has  discarded 
all  others,  and  in  his  reports  of  several  hundred  cases,  he 
says  that  he  has  seen  no  manifestation  of  pain  during  any 
amputation,  no  unhealthy  action  in  any  stump,  and  not 
a  single  death  to  mar  the  report."  The  manner  of  anaes- 
thetizing the  patient  seems  to  be  to  administer  one  or 
two  ounces  of  whiskey  by  the  mouth  every  ten  minutes 
"  until  complete  drunkenness  is  reached,"  and  then,  with 
or  without  one  or  two  inhalations  of  ether  or  chloroform, 
to  proceed  to  operate.  On  the  face  of  it,  this  procedure 
appears  to  be  open  to  righteous  condemnation.  It  is 
well  known  that  acute  gastritis  may  be  set  up  by  such 
means,  and  the  onus  of  proving  that  such  large  imbibi- 
tions of  alcohol  are  inoffensive  rests  with  Drs.  Link,  Kel- 
ler, and  others  who  may  choose  to  employ  the  drug.  It 
is  possible — anything  is  possible  in  medicine — that  such 
treatment  may  be  innocuous ;  but  until  more  accurate 
knowledge  is  forthcoming  we  prefer  to  believe  to  the  con- 
trary.— Lancet 

Every-Dav  Physiology. — The  weight  of  a  full-grown 
man  should  be  154  pounds,  distributed  as  follows  :  Mus- 
cles and  their  appurtenances,  68  pounds;  skeleton,  24 
pounds ;  skin,  10^  pounds  ;  fat,  28  pounds  ;  brains,  3 
pounds ;  thoracic  viscera,  3^  pounds ;  abdominal  vis- 
cera, 1 1  pounds  ;  blood  which  would  drain  from  body,  7 
pounds.  This  man  ought  to  consume  per  diem  :  Lean 
beefsteak,  5,000  grains  ;  bread,  6,000  grains  ;  milk,  7,000 
grains ;  potatoes,  3,000  grains ;  butter,  600  grains ;  and 
water,  22,900  grains.  His  heart  should  beat  72  times  a 
minute,  and  he  should  breathe  18  times  a  minute.  In  24 
hours  he  would  vitiate  1,750  cubic  feet  of  pure  air  to  the 
extent  of  one  per  cent. ;  a  man,  therefore,  of  the  weight 
mentioned  ought  to  have  800  cubic  feet  of  well-ventilated 


space.  He  would  throw  off  by  the  skin  18  ounces  of 
water,  300  grains  of  solid  matter,  and  400  grains  of  car- 
bonic acid  every  24  hours,  and  his  total  loss  during  the 
24  hours  would  be  6  pounds  of  water,  and  a  little  above 
2  pounds  of  other  matter. 

Dogmatic  Therapeutics. — The  following,  from  the 
Clinical  Record^  is  an  interesting  bit  of  dogmatic  teach- 
ing,  illustrating  its  attractiveness  and  its  dangers.  Item 
by  item  it  is,  if  not  absolutely  incorrect,  an  expression  of 
half-truth.  For  chronic  constipation,  Professor  DaCosta 
has  found  kneading  the  bowels  to  be  far  more  eflfectivc 
than  electricity.  The  best  American  water  for  this 
trouble  is  Saratoga  Congress,  but  no  water  should  be 
used  continuously.  Aloin  is  the  best  medicine,  and 
"  nothing  can  be  better  than  a  pill  of  aloin,  rheum,  bel- 
ladonna,  and  capsicum,  all  in  small  doses." 

Gastric  Hysteria  and  Reflex  Uterine  Vomiting. 
— Dr.  E.  Frank  Lyceston  propounds  four  queries  upon 
the  above  subject.  As  a  general  answer  we  can  only 
say  that  gastric  hysteria  and  hysterical  vomiting  may  be 
quite  independent  of  ovarian  or  uterine  irritation. 

Shakespeare's  Physician.  —  In  the  churchyard  at 
Fredericksburg,  Va.,  is  a  tombstone  on  which  may  be 
deciphered  these  words  : 

"  Here  lies  the  body  of 
EDWARD  HELDON, 
Practitioner  in  Physics  and  Chirurgery.  Bom  in  Bed- 
fordshire, England,'in  the  year  of  our  Lord  1542.  Was 
contemporary  with,  and  one  of  the  pall-bearers  of  William 
Shakespeare,  of  the  Avon.  After  a  brief  illness  his  spirit 
ascended  in  the  year  of  our  Lord  16 18 — aged  76." 

Increase  of  Epidemics  in  Paris. — All  epidemics, 
except  scarlet  fever,  have  increased  in  Paris  since  1865. 
The  deaths  from  measles  have  increased  from  31  to  46 
per  100,000  ;  from  pertussis,  10  to  19.5  ;  from  43  to  100. 
Dr.  Jacques  Bertillon,  who  gives  these  facts,  thinks  that 
there  ought  to  be  a  more  careful  medical  supervision  of 
public  schools. 

Mistakes  in  Words. — In  an  editorial  criticism  upon 
this  subject  the  Medical  I^ews,  says  the  Medical  Press 
and  Circular^  "  falls  into  the  error,  common  in  republics, 
of  assigning  the  quality  of  nobility  to  the  title  Sir,  since 
he  writes  that  William  Klame,  who  had  been  quoted  by 
Siredy  as  Sir  William  Klame,  is  a  poor  substitute  for 
William  Klapp,  and  it  isnot  compensated  for  by  the  title 
of  nobility  which  precedes  it" 

An    Observation    Regarding    Menstruation    in 
Animals. — Dr.  S.  A.  Evans,  of  Conway,  N.  H.,  writes : 
"  For  several  years  past  I  have  kept  a  nop  pregnant  cow, 
for  the  purpose  of  supplying  my  family  with  milk.     Have 
kept  a  record  of  periods  of  heat.     Find  they  recur  once 
in  twenty-one  days.     Are  accompanied,  first,  by  a  dis- 
charge of  gelatinous  material  from  vulva,  which,  after 
some  hours,  becomes  slightly  tinged  with  blood.  The  color 
becomes  gradually  more  pronounced,  until  within  twenty- 
four  hours  it  appears  to  be  pure  blood     Periods  last 
about  forty-eight  hours.     At  these  periods  only  can  the 
cow  become  impregnated,  which  would  seem  to  show 
that  in  her  case  ovulation  and  menstruarion  are  simultane- 
ous-    These  observations  have  extended  through  three 
winters,  and  in  two  different  animals.'' 

Half  a  Ton  of  Serum  from  the  Abdominal  CAvmf. 
—Dr.  D.  Dickinson,  Surgeon  U.  S.   N.,  Mare  Island, 

Cal.,  sends  us  the  following  note :  **  Nicholas  G , 

seaman,  native  of  Greece,  aged  twenty-eight  years  and 
two  months,  was  admitted  from  the  Naval  Hospital, 
Yokohama,  Japan,  on  August  18,  1884,  and  discharged 
for  transportation  East,  August  31,  1884,  as  he  was 
anxious  to  reach  Greece  before  he  should  die.  His  hos- 
pital ticket  stated  disease  to  be  dilatatio  cordis  (et  ascites). 
Within  the  past  seventeen  months  his  abdomen  has  been 
aspirated  sixty-nine  times,  withdrawing  nine  hundred  and 
forty-four  pints  (nearly  half  a  ton)  of  serum." 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  a6,  No.  22 


New  York,  November  29,  1884 


Whole  No.  734 


(J^rtfiitmX  ^xXitUs. 


THE  APPROACH  OF  THE  CHOLERA  AND  THE 

NECESSITY  OF  BACTERIOSCOPY. 

By  EDMUND  C.  WENDT,  M.D., 

NBW  YORK. 

The  epidemic  of  cholera  which  commenced  last  June  at 
Toulon,  has  already  killed  many  thousands.  It  still  con- 
tinues to  spread,  fortunately,  however,  with  diminished 
fatality.  Nevertheless,  the  experience  of  past  epidemics 
should  warn  us  of  the  possibility — nay,  even  probability — 
of  its  being  carried  across  the  ocean  to  our  own  shores. 
Indeed,  most  authorities  confidently  anticipate  its  ap- 
proach next  year.  Now,  unless  we  take  efficient  action 
in  the  matter  while  there  is  yet  time,  the  dreaded  scourge 
may  find  us  so  poorly  prepared  that  widespread  disaster 
must  inevitably  result. 

As  has  been  pointed  out  by  Sanitary  Engineer  Win- 
gate  in  a  leading  daily,  published  November  23d,  "  de- 
spite the  precautions  taken  by  the  health  officials,  no  one 
who  is  at  all  familiar  with  the  sanitary  condition  of  New 
York  City  can  doubt  that  if  the  plague  once  gains  an  en- 
trance into  the  metropolis,  it  will  find  many  nesting  places 
among  the  dives  and  slums  in  certain  quarters,  whence 
its  baleful  influence  will  spread  far  and  wide.  Chief 
among  these  hotbeds  of  disease  which  constantly  invite 
infection,  are  the  Italian  and  Hebrew  quarters,  the  former 
occupying  the  region  of  Mulberry,  Baxter,  and  Crosby 
Streets,  and  the  latter  the  district  in  the  vicinity  of  Lud- 
low, Essex,  Hester,  and  Forsyth  Streets."  The  nuisances 
on  the  east  side  of  the  city  are  likewise  a  source  of  con- 
stant discomfort  and  serious  danger.  The  same  journal 
has  the  following  editorial  comment  relative  thereto  : 

**  This  evil  is  none  the  less  great  because  of  its  long 
standing.  But  legal  obstacles,  red  tape,  procrastination, 
or  what  not,  have  resulted  in  the  continued  exposure  of 
our  citizens  to  the  emanations  of  manure  heaps,  stagnant 
drainage,  and  reeking  vats.  Here  is  added  cause  for 
Herbert  Spencer's  wonder  at  the  long-suffering  and  pa- 
tience of  Americans  under  imposition.  A  complaint  has 
been  lodged  before  the  State  Board  of  Health,  and  a 
heroic  band  of  Beekman  Hill  women  have  invaded  the 
pestilential  haunts  of  the  malodorous  offenders  and 
secured  testimony  for  the  consideration  of  the  Grand 
Jury.  These  women  have  pluckily  taken  in  hand  duties 
which  devolve  upon  our  Health  Department.  They 
have  had  the  courage  of  their  convictions.  Where  are 
the  courage  and  the  convictions  of  the  officials  supposed 
'  to  care  for  the  sanitary  conditions  of  this  city  ?  " 
I  At  present  **  it  is  more  important  than  ever  before  that 
I  the  people  of  this  city  should  live  under  the  best  sanitary 
conditions.  The  east  side  nuisances  have  been  endured 
too  long.  They  should  have  been  abolished  long  ago. 
They  must  be  done  away  with  now." 

Such  impressive  warnings  should  not  go  unheeded. 
And  it  is  quite  creditable  to  our  Quarantine  Department 
that  it  shows  renewed  vigilance  in  the  matter  of  pre- 
venting contagious  diseases  from  entering  our  city. 
Nevertheless,  the  fact  that  a  fatal  case  of  yellow  fever 
has  been  quite  recently  introduced  into  the  city  through 
the  failure  of  the  authorities  to  detect  the  disease,  shows 
that  the  medical  service  of  Quarantine  is  not  altogether 
what  it  should  be.  This  is  still  further  shown  by  a  reso- 
lution adopted  at  the  last  meeting  of  the  State  Board  of 
Health,  held  a  few  days  ago,  calhng  the  attention  of  the 


Governor  to  the  bad  condition  of  the  buildings  and  equip- 
ments at  Quarantine,  and  recommending  that  proper 
steps  be  taken  for  putting  them  in  perfect  order. 

In  the  London  Practitioner  for  November,  1884,'  there 
appears  a  careful  report  of  the  present  cholera  epidemic  in 
Continental  Europe,  which  shows  conclusively  that  the 
secret  of  success  in  carrying  into  effect  the  system  of 
medical  inspection  and  isolation  is  to  be  prepared  before- 
hand. And  it  is  impossible  to  urge  too  strongly  upon 
local  authorities,  whether  on  the  coast  or  inland,  the 
adoption  of  such  an  organization  and  the  establishment 
of  such  means  of  isolation  as  shall  enable  them  to  deal 
with  imported  infection  in  its  earliest  stage. 

Dr.  Buchanan,  F.R.S.,  in  an  excellent  article  on  "Pre- 
cautions against  the  Infection  of  Cholera,"  points  out 
that,  it  is  important  for  the  public  very  distinctly  to  re- 
member that  pains  taken  and  costs  incurred  for  these 
pui^poses  cannot  in  any  event  be  regarded  as  wasted. 
The  local  conditions  which  would  enable  cholera,  if  im- 
ported, to  spread  its  infection  in  any  country,  are  con- 
ditions which  day  by  day,  in  the  absence  of  cholera, 
create  and  spread  other  diseases :  diseases  which,  as 
being  never  absent  from  the  country,  are  in  the  long  run 
far  more  destructive  than  cholera  itself.  The  sanitary  im- 
provements which  would  justify  a  sense  of  security  against 
any  apprehended  importation  of  cholera  would,  though 
cholera  should  never  reappear,  give  amply  remunerative 
results  in  the  prevention  of  those  other  diseases. 

The  Practitioner  says  further  as  having  a  bearing  on 
this  point,  "It  is  also  worthy  of  note  that  the  value  of 
being  prepaied  in  advance  has  been  strikingly  illustrated 
during  the  course  of  the  Italian  epidemic.  The  contrast 
between  Naples  and  Rome  supplies  the  illustration.  In 
Naples  cholera,  when  once  imported,  found  in  the  results 
of  centuries  of  sanitary  neglect  a  soil  congenial  to  its 
rapid  development,  and  terribly  the  city  has  suffered  in 
consequence.  But  Rome  had  learned  a  lesson  which  even 
the  history  of  previous  epidemics  had  not  impressed  on  Na- 
ples. The  Eternal  City  had  provided  itself  with  an  abun- 
dant and  wholesome  water  supply,  and  with  an  efficient 
system  of  sewerage,  and  it  had,  in  addition,  adopted  other 
measures  calculated  to  promote  the  health  of  its  inhabit- 
ants; the  result  being  that,  although  cholera  was  on  five  sep- 
arate occasions  imported  into  the  city,no  difficulty  was  expe- 
rienced.by  means  of  measures  of  isolation  and  other  sanitary 
precautions,  in  preventing  any  spread  of  the  infection." 

It  is  to  be  hoped  that  such  positive  lessons  may  not 
prove  barren  of  practical  results.  But  while  physicians 
and  sanitarians  are  fully  alive  to  the  danger  before  us, 
they  have  neglected  one  point  that  may  be,  and  probably 
is,  of  the  highest  importance.  It  is  obvious  that  the 
earliest  possible  recognition  of  the  very  first  case  of 
cholera  that  might  appear"  among  us,  would  give  us  the 
best  chance  for  prompt  action  to  prevent  any  extension 
of  the  disease.  Now,  it  is  a  lamentable  fact  that  the  most 
careful  analysis  of  symptoms  does  not  always  enable  us  to 
distinguish,  in  a  given  case,  cholera  morbus  from  genuine 
Asiatic  cholera.  Indeed,  it  is  held  by  some  physicians 
that  the  two  diseases  differ  in  degree  only,  and  not  in  kind. 

Without  stopping  to  consider  this  point,  we  must  yet 
face  the  fact  that  our  usual  methods  are  inadequate  to 
differentiate  with  absolute  certainty  an  attack  of  violent 
and  fatal  cholera  morbus  from  one  of  true  cholera.  The 
kind  of  reasoning  hitherto  employed  by  physicians  has 
necessarily  been  of  the  d  posteriori  variety.  That  is  to 
say,  if  a  suspicious  case  recovered,  and  was  not  soon  fol- 


L 


590 


THE  MEDICAL  RECORD. 


[November  29,  1884. 


lowed  by  other  and  rapidly  fatal  cases,  the  disease  was 
classed  as  cholera  morbus.  If,  on  the  other  hand,  the 
first  suspicious  case  was  quickly  followed  by  an  increas- 
ing number  of  fatal  cases,  the  diagnosis  of  Asiatic  cholera 
was  subsequently  made.  Manifestly,  a  method  of  this 
kind  might  give  the  cholera  a  chance  to  secure  a  danger- 
ous foothold  before  being  recognized  as  such  ;  and  one 
need  not  be  an  alarmist  to  entertain  grave  apprehensions 
should  such  a  misfortune  befall  us.  But  in  view  of  recent 
discoveries,  it  now  seems  possible  to  decide  positively 
and  in  a  very  short  time  whether  we  are  dealing  with  the 
comparatively  benign  cholera  nostras,  or  with  the  emi- 
nently mali^ant  Asiatic  cholera. 

The  findmg  of  the  specific  organism  of  cholera  by 
Koch  was  no  surprise  to  those  who  had  long  since  con- 
cluded, without  this  final  and  convincing  evidence,  that 
cholera  must  be  a  parasitic  disease  caused  by  a  particular 
and  distinct  microbe.  The  grounds  on  which  Koch 
based  his  assertion  that  the  comma-bacillus  was  the 
causative  agent  of  cholera  were,  that  it  was  found  to  be 
present  in  all  well-marked  cases  of  the  disease,  and, 
further,  that  it  was  never  present  in  the  healthy  body  or 
in  cases  of  any  other  disease. 

Koch's  conclusions  were  accepted  without  hesitation 
by  those  who  know  him  best,  and  who  have  had  occasion 
to  witness  his  conscientious  and  painstaking  methods  of 
conducting  all  scientific  work.  Thus,  in  Germany,  Herr 
Von  Gossler,  Minister  of  Public  Worship,  Education,  and 
Medical  Afifairs,  has  already  ordered  that  a  certain  num- 
ber of  medical  men  are  to  be  summoned  to  Berlin  every 
year  to  go  through  a  course  of  study,  lasting  from  a  fort- 
night to  three  weeks,  in  order  to  learn  the  new  methods 
of  investigation  connected  with  bacteria  and  micro- 
organisms, but  chiefly  to  become  acquainted  with  every- 
thing connected  with  the  comma-bacillus  and  the  methods 
of  cultivating  it  according  to  Koch's  method  The  several 
Federal  Governments  have  been  likewise  officially  re- 
quested to  select  a  number  of  medical  men  for  this 
course,  and  to  inform  them  to  hold  themselves  in  readi- 
ness to  come  to  Berlin.  According  to  the  latest  Berlin 
advices  these  courses  are  now  in  active  operation,  and 
are  very  largely  attended. 

In  our  own  country,  however,  there  is  still,  even  in  the 
ranks  of  the  medical  profession,  an  unfortunate  disposition 
to  regard  the  entire  subject  of  bacteria  as  trivial  or  fan- 
ciful, and  unworthy  of  serious  consideration.  There  are 
of  course  some  notable  exceptions  to  this  rule.  Thus  Dr. 
Austin  Flint,  Sr.,  in  a  recent  paper  on  cholera  expressed 
his  unqualified  belief  in  the  truth  of  Koch's  assertions. 
He  showed  that,  wherever  cholera  appeared  the  com- 
plete destruction  of  the  parasite  directly  it  left  the  body 
could  be  secured,  and  by  this  means  every  case  of  the 
disease  would  be  rendered  sterile.  Koch  had  proved 
that  the  cholera  microbe  was  readily  killed  by  drying, 
while  cold  did  not  destroy  its  vitality,  The  local  con- 
ditions under  which  the  parasite  would  thrive  best  out- 
side the  body  were  not  yet  definitely  known,  but  there 
could  be  no  doubt  whatever  that  filth  was  very  favor- 
able to  its  development.  Inside  the  body  Koch  had 
shown  that  the  acidity  of  the  gastric  fluids  was  inimical 
to  it.  In  order  that  an  individual  should  contract  chol- 
era it  was  probable  that  there  should  be  a  predisposition 
or  susceptibility  to  it,  as  was  the  case  in  tuberculosis. 
Hence  when  we  hear  it  credibly  reported  that  Dr. 
Klein,  of  London,  a  member  of  the  English  Cholera 
Commission  now  investigating  the  disease  in  India, 
in  order  to  show  his  disregard  for,  and  lack  of  faith  in, 
Koch's  comma-bacilli,  made  a  meal  of  them,  we  can  well 
afford  to  laugh  at  such  puerile  business.  Indeed,  the 
Berliner  Klinische  Wochenschrift  ^2.y%  :  "  We  had  looked- 
for  something  better  from  Dr.  Klein,  and  must  confess 
that  this  so-called  auto-experiment  gives  us  no  great  idea 
of  the  discernment  and  powers  of  criticism  of  the  above- 
named  gentleman."  And  the  British  Medical  Journaly 
fully  appreciating  how  ridiculous  the  affair  is,  states  that 
everybody  in  London  ridicules  the  experiment. 


To-day  there  seems  no  longer  any  possible  doubt  about 
the  significance  of  the  cholera  bacillus.  In  the  German 
Medical  Weekly  of  November  6,  1884,  just  to  hand, 
Koch  has  finally  disposed  of  the  various  objections  that 
had  been  made  against  the  binding  force  of  his  asser- 
tions. He  has  proved  by  actual  scientific  demonstra- 
tions that  the  comma-bacillus  is  the  specific  micro-or- 
ganism of  genuine  Asiatic  cholera.  The  disease  has  also 
been  artificially  produced  in  animals  by  the  introduction 
of  pure  cultures  of  the  parasite  in  question. 

It  is  not  necessary  here  to  reproduce  Koch's  last  article; 
enough  has  been  said  to  show  that  in  scientific  bacterios- 
copy  we  have  quite  possibly  a  ready  means  of  detecting 
with  certainty  the  existence  of  cholera.  But  in  order  to 
familiarize  ourselves  with  the  necessary  details  of  these 
modem  methods,  earnest  study  and  some  experience  are 
essential  I  hold  that  we  have  not  the  right  to  ignore 
the  light  that  has  been  shed  on  the  true  nature  of  in- 
fectious diseases  by  the  keenly  searching  spirit  of  mod- 
ern experimental  inquiry.  In  my  opinion,  it  is  the  duty 
of  our  Government  to  imitate  what  has  been  already 
done  abroad.  Physicians,  or  other  competent  persons, 
should  be  sent  to  Berlin  at  the  expense  of  individual 
States,  or  the  Federal  Government,  to  join  the  classes 
that  have  just  been  organized  under  Koch^s  supervision. 
They  should  become  personally  familiar  with  every  step 
of  his  painstaking  and  strictly  scientific  methods.  In  a 
few  weeks,  or  at  most  months,  they  could  return  and  be 
experts  and  teachers  of  modern  bacteriology. 

Should  this  be  found  impracticable,  however,  then  let  the 
State  Health  Boards  organize  properly  equipped  labora- 
tories for  the  purpose  of  affording  suitable  facilities  for 
this  kind  of  study  and  research.  Individual  physicians 
with  sufficient  time  and  private  means  should  take 
an  active  interest  in  all  that  relates  to  the  examination 
and  cultivation  of  bacteria.  Is  the  medical  profession 
of  our  country  to  be  put  to  shame  by  its  attitude  of 
apathy  toward  matters  of  serious  concern  to  the  public 
welfare  ?  Are  we  to  be  made  the  laughing-stock  of  oar 
transatlantic  confreres  ?  Two  well-known  physicians  of 
our  country  have  already  attempted  to  overthrow  the 
diagnostic  significance  of  the  bacillus  of  tubercular  con- 
sumption, the  one  by  claiming  it  to  be  a  fat-crystal,  the 
other  by  asserting  its  identity  with  shreds  of  fibrin.  But 
neither  the  one  nor  the  other  had  at  the  time  of  his  pre- 
tended discovery  ever  beheld  the  true  bacillus  tubercu- 
losis. To  avoid  similarly  ridiculous  errors  we  need  ex- 
pert teachers  of  bacterioscopy.  This  new  and  highly 
important  branch  of  medicine  should  be  made  an  essen- 
tial and  obligatory  part  of  the  regular  medical  curriculum. 

That  scienti.nc  bacteriology  is  as  yet  in  its  infancy  all 
will  admit.  But  let  us  not  blindly  ignore  its  actual  ac- 
complishments. We  may  never  be  able  perhaps  to  com- 
pletely eradicate  consumption  or  suppress  all  contagious 
diseases,  but  at  present  we  are  without  the  slightest 
doubt  nearer  to  such  a  desirable  consummation  than  we 
were  before  the  era  of  bacterioscopy.  This  is  a  most  im- 
portant epoch  in  medicine,  and  it  has  been  well  said  by 
an  eminent  physician  of  New  York :  **  It  would  be  to  the 
present  era  that  posterity  would  look  back  as  the  time 
when  those  signal  discoveries  were  made  which  led  to 
the  final  adoption  of  the  parasitic  theory  of  the  origin  of 
all  infectious  diseases.  Was  the  medical  profession  in 
this  country  to  have  an  active  share  in  this  great  work  of 
investigation  and  in  these  brilliant  discoveries,  or  was  it 
to  be  content  to  wait  patiently  until  the  announcements 
of  the  results  of  their  labors  were  made  by  the  scientific 
men  of  Europe  ?  There  was  certainly  no  lack  of  ability 
on  the  part  of  American  medical  men,  but  it  seemed  to 
him  that  there  was,  at  all  events,  a  certain  want  of  self- 
reliance  and  energy."  •  If  our  State  authorities  are  unable 
or  unwilling  to  help  the  good  work,  let  the  munificence 
of  private  citizens  proclaim  to  the  world  that  democracy 
is  at  least  not  inferior  to  paternal  forms  of  government 
in  producing  noble  specimens  of  the  genus  homo. 

xoa  East  Fifty-sevknth  Strbkt,  November  as,  1884. 


\ 


November  29,  1884.] 


THE   MEDICAL  RECORD. 


591 


CASES    OF    STRANGULATED    HERNIA,  WITH 
REMARKS  ON  TREATMENT/ 

By  GEORGE   F.   SHRADY,  A.M.,  M.D., 

NBW  YORK. 

During  the  past  few  months  in  my  service  at  St.  Francis' 
Hospital,  I  have  had  rather  an  unusual  experience  with 
strangulated  hernia,  in  the  number  of  cases  treated  with- 
in a  short  period.  It  rarely  happens  in  the  general  sur- 
gical practice  of  our  hospitals  that  any  surgeon  is  called 
upon  to  operate  upon  eight  cases  within  a  period  of  seven 
months.  To  this  number  majr  be  added  one  occurring  in 
private  practice,  in  consultation  with  my  friend  Dr.  Mc- 
Crecry,  making  a  total  of  nine.  When  it  is  also  stated 
that  in  these  herniotomy  was  successfully  performed,  we 
can  scarcely  go  farther  in  estimating  the  results  of  a  desir- 
able experience.  It  has  occurred  to  me  that,  with  the  risk 
of  not  presenting  anything  strikingly  novel  to  the  surgeon, 
some  remarks  addressed  to  the  general  practitioner,  and 
based  upon  personal  experience  in  these  and  other  cases, 
might  under  present  circumstances  be  acceptable. 

A  leading  physician  in  a  rural  district  once  remarked 
that  it  was  always  interesting  to  him  to  learn  what  was 
the  treatment  of  the  ordinary  diseases  in  the  large  metro- 
politan hospitals.  Even  the  details  of  such  practices, 
commonplace  as  they  might  appear  to  be,  were  assur- 
ances to  him  that  nothing  better  was  known.  With  a 
view  also  of  making  a  contribution  from  such  a  stand- 
point these  cases  are  presented,  in  the  hope  that  the 
consideration  of  some  practical  points  connected  with 
them  may  elicit  discussion.  It  is  not  proposed  to  give 
more  than  a  brief  outline  of  their  histories.  In  so  doing 
I  have  availed  myself  of  the  notes  of  Dr.  J.  H.  B.  Brown- 
ing, House-Surgeon  to  St.  Francis'  Hospital. 

It  is  presumably  unnecessary  to  say  that  in  all  these 
cases  there  were  well  marked  symptoms  of  strangulation, 
inability  to  return  the  gut  by  judicious  taxis,  and  unmis- 
takable local  evidences  of  firm  constriction  of  the  gut  it- 
self demonstrated  by  the  operations. 

Case  I. — Jacob   P ,  aged  forty,  was  admitted  to 

St.  Francis'  Hospital,  New  York,  March  4,  1884,  the  third 
day  after  the  appearance  of  symptoms  of  strangulated 
hernia.  Vomiting  was  stercoraceous,  pulse  small,  feat- 
ures pinched,  surface  cool,  with  other  symptoms  of  general 
prostration.  The  hernial  tumor  in  the  right  groin  was 
not  noticed  by  the  patient  until  immediately  after  a 
strain,  three  days  before.  The  patient  was  etherized, 
and  judicious  taxis  having  failed,  herniotomy  was  per- 
formed without  delay.  A  single  knuckle  of  small  intes- 
tine was  involved.  Its  surface  was  of  a  brownish  hue, 
was  mottled  with  extravasations,  but  at  no  point  was  it 
gangrenous.  After  dividing  the  point  of  constriction  at  the 
neck  of  the  sac,  the  circulation  of  the  gut  was  restored  un- 
der the  application  of  hot  moist  towels,  and  the  hernia  duly 
returned.  The  wound  healed  by  first  intention,  and  the  pa- 
tient was  discharged  well,  April  2,  1884,  with  the  advice  to 
maintain  inguinal  support  for  a  period  of  several  months. 

Case  II. — Catharine  B ,  aged  sixty-five,  was  ad- 
mitted to  the  same  hospital,  March  15, 1884,  with  so-called 
dyspeptic  symptoms,  associated  with  a  tumor  in  the  left 
^oin.  A  careful  examination  revealed  the  existence  of  an 
ureducible  femoral  hernia,  but  the  patient  could  give  no 
intelligible  account  of  symptoms  of  strangulation.  In 
the  course  of  a  few  hours  persistent  vomiting  with  col- 
icky pains  occurred.  It  was  then  ascertained  that  these 
were  the  dyspeptic  symptoms  from  which  she  had  sufifered 
for  the  previous  two  days,  and  that  up  to  that  time  she 
had  been  able  to  *^put  the  bowel  back."  In  short,  the 
case  turned  out  to  be  one  of  strangulated  femoral  her- 
nia, and  was  operated  upon  without  delay. 

The  gut  was  found  to  be  gangrenous  at  a  point  where 
it  impinged  upon  the  edge  of  the  unyielding  crural  open- 
ing. The  sloughing  portion  was  removed,  the  edges  of 
the  wound  in  the  gut  closed,  and  in  turn  attached  to  the 

» Read  before  the  Practitioners'  Sodcty  of  New  York,  November  7,  1884. 


margin  of  the  ring.  The  two  or  three  lower  stitches  of 
the  wound  gave  way  at  the  end  of  the  fourth  day,  and 
through  the  opening  thus  made  there  was  a  small  dis- 
charge of  fecal  matter.  By  means  of  compress  dressings 
the  fecal  fistula  closed  after  a  week  or  more,  the  re- 
maining wound  healing  by  granulation.  This  patient, 
just  as  she  was  ready  to  leave  the  hospital  at  the  end  of 
the  fifteenth  day,  was  seized  with  a  double  pneumonia, 
from  which  she  died  on  the  third  day.  This,  it  is  true, 
was  a  case  of  death,  but  not  as  the  result  of  a  successful 
operation,  as  the  grim  humor  of  an  old  saw  might  have  it. 

Case  III.  was  that  of  G.  P ,  aged  seventy-three. 

He  was  admitted  to  St.  Francis'  Hospital  March  27, 1884. 
Two  days  before,  an  old  inguinal  hernia  on  the  left  side 
had  come  down  after  a  slight  strain,  and  could  not  be 
returned.  A  physician  was  sent  for  who  made  vigorous 
efforts  at  taxis.  Vomiting  then  took  place,  and  continued 
more  or  less  until  he  was  seen  in  the  ward.  The  hernial 
tumor  was  very  tender  and  turgid.  The  pulse  was  very 
feeble,  and  the  patient  was  quite  exhausted.  The  strict- 
ure, which  was  at  the  neck  of  the  sac,  was  divided,  and 
the  mahogany-colored  gut  was  nursed  in  hot  moist  cloths 
for  a  full  half  hour  before  it  could  be  returned.  The 
wound  healed  by  second  intention,  the  granulations  and 
subsequent  cicatrization  completely  plugging  up  the 
hernial  opening.  The  case  progressed  without  a  bad 
symptom,  notwithstanding  the  bowels  did  not  move  until 
the  fourteenth  day  after  the  operation. 

Case  IV. — John  B ,  aged  forty-one,  was  admitted 

to  St.  Francis*  Hospital,  April  23,  1884.  The  day  be- 
fore, while  in  the  act  of  lifting  a  heavy  box,  an  old  hernia 
in  his  left  groin  was  forced  down,  and  became  very  hard 
and  immovable.  Pain  and  emesis  occurred  two  hours 
after,  and  continued  at  short  intervals  during  the  follow- 
ing night.  Stercoraceous  material  was  being  vomited  on 
admission.  The  usual  signs  of  strangulation  were  pres- 
ent Fortunately,  but  little  taxis  had  been  employed  out- 
side the  ward.  Herniotomy  was  performed  without  delay. 
One  large  knuckle  of  gut  was  found  to  be  firmly  constricted, 
diffusely  mottled,  and  mahogany  colored.  Wound  healed 
by  first  intention.     Patient  discharged.  May  25,  1884. 

Case  V. — James  R ,   aged    sixty-one,  began    to 

suffer  from  strangulation  of  an  old  hernia  on  the  morning 
of  May  10,  1884,  and  was  admitted  twelve  hours  after 
with  well-pronounced  symptoms,  including  stercoraceous 
vomiting.  There  had  been  so  much  taxis  employed  pre- 
vious to  admission  that  the  parts  were  much  swollen,  in- 
flamed, and  tender.  Portions  of  gut  and  omentum  were 
involved  in  strangulation.  The  gut,  when  exposed,  was 
found  to  be  of  a  dull  brownish  color,  and  somewhat 
oedematous.  The  fluid  in  the  sac  was  .  dark-colored. 
Omentum  was  deeply  congested.  Circulation  in  gut  re- 
stored under  hot  applications.  The  strangulated  omen- 
tum, which  was  of  small  size,  was  duly  excised.  The  day 
after  operation  tlie  temperature  was  ioi^°  F.  Subse- 
quently there  was  nothing  worthy  of  note,  save  that  the 
stitches  gave  way  in  the  wound,  the  latter  closing  by 
granulation,  and  apparently  permanently  curing  the  her- 
nia. The  bowels  moved  on  the  seventh  day.  Patient 
wasdischarged  June  9,  1884.   ' 

Case  VI. — Theodore  J ,  aged  sixty-two,  had  an 

old  inguinal  hernia  also,  which  became  strangulated  after 
a  violent  effort  at  coughing,  on  June  10,  1884.  He  was 
admitted  to  the  hospital  the  same  day  in  an  extreme  state 
of  prostration  from  a  persistent  vomiting  of  several  hours. 
Herniotomy  was  performed  within  eighteen  hours  after  the 
accident.  A  large  knuckle  of  gut  was  in  a  dark -brownish, 
mottled  condition,  but  its  circulation  was  duly  restored  un- 
der application  of  towels  wrung  out  of  hot  water.  A  portion 
of  omentum,  also  strangulated,  was  ligated  and  removed. 
The  wound  healed  by  granulation.  Patient  was  discharged, 
apparently  radically  cured  of  hernia,  August  3,  1884. 

Case  VII. — F.  W ,  aged  forty  years,  while  lifting 

forced  down  an  old  inguinal  hernia,  which  became  stran- 
gulated. Within  a  very  little  while  after  the  accident  he 
grew  faint,  was  nauseated,  and  vomited  the  stomach  con- 


592 


THE  MEDICAL  RECORD. 


[November  29,  1884. 


tents.  In  spite  of  a  determination  to  continue  at  his 
work  he  was  forced  to  go  home,  when  vomiting  recurred 
and  continued  more  or  less  for  two  days.  When  admitted 
to  hospital  at  the  end  of  that  period,  August  20,  1884,  he 
was  much  exhausted.  He  was  unable  to  retain  water  in 
his  stomach,  and  the  slightest  movement  was  attended 
with  a  retching  gulp.  Herniotomy  was  performed  as 
soon  as  the  patient  could  be  anaesthetized,  forty-nine  hours 
after  strangulation.  The  ^t,  which  was  a  single  knuckle, 
was  firmly  constricted  in  its  whole  circumference,  but  not 
gangrenous.  The  wound  healed  by  first  intention,  and  the 
patient,  when  discharged,  September  15,  1884,  gave  no 
evidences  of  a  return  of  the  hernia.  The  bowels  moved 
naturally  on  the  fifth  day. 

Case  VIII. — A.  G ,  aged  eighteen,  while  adjusting 

a  portion  of  the  load  on  his  truck  felt  a  giving  way  in  his 
right  groin,  and  immediately  after  found  a  good- sized  ob- 
long tumor  extending  into  his  scrotum.  Feeling  very  faint, 
and  suffering  frorp  considerable  pain,  he  went  to  his  home. 
There  the  pain  increased  and  free  emesis  occurred.  A 
physician  was  sent  for,  who,  recognizing  the  condition,  at- 
tempted to  reduce  the  gut  and  failed.  The  patient  was 
allowed  to  rest  until  next  day,  when  efforts  at  taxis  were 
renewed,  also  without  avail.  Vomiting  by  this  time  had 
become  so  violent  and  persistent  that  the  patient  was 
sent  to  the  hospital,  after  having  suffered  from  symptoms 
of  strangulation  for  three  days.  The  diagnosis  of  con- 
genital strangulated  hernia  was  then  made  and  subse- 
quently confirmed. 

On  slitting  open  the  sac  there  was  a  gush  of  dark 
venous  blood,  which  came  from  the  previous  rupture  of 
a  vein  in  a  lafge  mass  of  strangulated  omentum.  To- 
gether with  this  epiplocele  there  was  an  cedematous, 
ashy-colored,  mottled  knuckle  of  gut,  which  at  first  sight 
appeared  to  be  hopelessly  gangrenous.  The  omentum, 
which  had  forced  its  way  into  the  sac  of  the  tunica  vaginalis, 
was  withdrawn,  and  found  to  be  so  suspiciously  mottled  and 
inflamed  that  its  veins  were  at  first  carefully  ligated  sep- 
arately and  then  en  masse,  and  the  whole  was  cut  off. 
This  portion  of  omentum  measured  15^  inches  in  one 
diameter,  and  8^  in  another.  The  omental  stump  was 
used  as  a  plug  for  the  hernial  canal.  There  were  recent 
adhesions  between  the  strangulated  gut,  which  were  care- 
fully severed.  It  required  fully  twenty-five  minutes  of 
soakage  of  the  gut  in  hot,  moist  towels  to  insure  its  being  in 
a  proper  condition  for  return.  The  wound,  on  account  of 
previous  inflammation  around  it,  did  not  close  by  first  in- 
tention throughout.  It  opened  at  its  lower  portion,  and 
eventually  healed  by  granulation,  leaving  the  hernia,  as 
I  believe,  radically  cured.  The  bowels  moved  on  the 
ninth  day. 

When  Dr.  Browning,  the  House-Surgeon  of  St.  Francis' 
Hospital,  called  on  me  with  the  foregomg  histories,  which 
he  had  kindly  prepared  for  my  perusal,  I  found  that  there 
were  but  eight  cases  instead  of  nine,  as  I  expected.  By 
a  curious  coincidence  my  friend  and  neighbor.  Dr.  J.  A. 
McCreery,  called  the  same  morning  (October  13,  1884), 
asking  me  to  operate  on  the  following  case  of  strangu- 
lated femoral  hernia  in  his  practice  : 

Case  IX. — Mrs.  M ,  aged   thirty-five   years,  had 

suffered  from  a  reducible  femoral  hernia  for  years,  wear- 
ing a  truss  most  of  that  time.  On  the  evening  of  the 
day  before  she  was  seized  with  a  severe  fit  of  vomiting, 
which  she  thought  was  due  to  the  gastric  disturbances 
of  pregnancy,  she  being  three  months  advanced  in  that 
condition.  When  she  recovered  from  the  attack,  she 
discovered  that  the  hernia  was  much  larger  and  im- 
movable. After  several  fruitless  attempts  to  return  the 
gut  she  summoned  Dr.  McCreery,  who  in  turn  asked  me 
to  see  her  with  him.  I  did  so  without  delay,  discovered 
a  strangulated  femoral  hernia,  and  performed  herniotomy 
at  once,  with  the  result  of  relieving  immediately  all  the 
urgent  symptoms.  The  sac  contained  darkly  colored 
gut  and  a  small  nodule  of  omentum.  These  were  both 
restored,  and  returned  after  the  stricture  was  liberated. 
The  patient  has  made  a  perfect  recovery. 


So  much  for  the  synopsis  of  the  cases.  It  is  always 
worth  our  while  in  noting  successes  to  explain,  as  best  we 
can,  the  reasons  for  them.  Even  if  for  the  most  part 
they  be  not  new,  they  have  at  least  the  merit  of  being 
true,  thus  adding  weight  to  practical  experience.  Such, 
at  least,  is  a  healthy  offset  to  methods  which  may  be  new, 
and  yet  not  true.  But  let  us  remark  on  the  matter,  in  a 
general  way,  that  we  may  lake  a  short  cut  to  conclusions. 

My  experience  with  cases  of  strangulated  hernia  has 
taught  me  that  taxis  is  very  much  overdone.  Hardly  a 
case  comes  to  us  which  is  not  the  worse  for  it.  The 
temptation  to  use  more  or  less  force  is  too  great  for  most 
men  to  resist.  The  late  Professor  Oilman,  in  his  admi- 
rably impressive  lectures  on  obstetrics,  would  charge  his 
hearers  not  to  grasp  the  cord  in  attempting  to  deliver  the 
placenta.  *'  If  you  have  a  temptation  to  pull  it,  it  is  bet- 
ter not  to  touch  it  at  all.*'  Discreet  teachers  of  surgery 
tell  their  students  to  use  only  a  soft  catheter  to  empty 
the  bladder,  and  for  a  like  reason.  Few  beginners  un- 
derstand what  is  meant  by  merely  guiding  a  solid  instru- 
ment through  the  deep  urethra,  as  3iere  is  almost  always 
an  irresistible  tendency  to  push  it  along  its  course.  I 
would  say  to  the  practitioner  who  is  not  prepared  to 
operate  for  strangulated  hernia,  that  a  safe  rule  is  not  to 
persist  in  taxis  after  the  first  judiciously  gentle  efforts  at 
reduction.  If  he  goes  beyond  this  he  rarely  appreciates 
how  much  force  he  is  apt  to  employ  before  he  is  willing 
to  give  up  the  fight  to  another.  The  patient  generally 
has  the  best  chance  with  no  taxis  at  all  until  he  is  ether- 
ized for  a  possible  herniotomy.  No  time  is  thus  lost,  and 
the  operation  can  be  performed  as  soon  as  it  is  decided 
that  taxis  availeth  not. 

Every  one  knows  the  rule  to  operate  at  once  on 
an  irreducible  strangulated  hernia.  This  goes  with- 
out the  saying.  I  am  convinced,  however,  that  there 
are  many  who  do  not  appreciate  its  full  force,  even 
when  cases  are  recognized  early.  There  seems  to  be 
a  temptation  to  hope  against  hope  that  an  operation 
may  be  avoided.  And  yet  the  operation  in  itself  is  not 
dangerous.  Even  in  case  of  doubt  in  diagnosis,  and  there 
are  not  a  few  of  such  to  which  this  remark  will  apply,  it 
is  safer  to  herniotomize  the  patient  than  to  let  him  alone, 
trusting  to  chances.  Every  practitioner  of  large  experi- 
ence can  call  to  mind  cases  mistaken  up  to  the  last 
moment,  when  hope  for  saving  has  virtually  passed,  and 
when  herniotomy  is  blamed  for  throwing  the  balance  on 
the  wrong  side. 

Even  such  cases  should  not,  however,  be  looked  upon 
as  absolutely  desperate  ones.  Mr.  Birkett  refers  to  a 
femoral  hernia  which  had  been  strangulated  for  fourteen 
days,  and  upon  which  successful  herniotomy  was  finally 
performed.  In  view  of  this  fact  it  is  the  duty  of  every 
surgeon  to  operate  upon  cases  of  long-continued  strangu- 
lation, unless  the  ])atient  be  actually  moribund  at  the 
time.  In  one  of  the  successful  cases  reported  the  symp- 
toms had  lasted  for  forty-nine  hours. 

It  is,  of  course,  not  always  easy  to  decide  whether  or 
no  strangulation  actually  exists.  The  rule  should  always 
be  to  give  the  benefit  of  the  doubt  to  the  operation,  and 
act  promptly.  The  main  tests  for  strangulation  are  pain,  . 
tenderness,  and  continuous  vomiting,  with  a  recently  irre- 
ducible hernial  tumor.  Men  in  hospital  practice,  who  see 
a  great  deal  of  hernia,  always  examine  the  groin  when 
persistent  vomiting  exists.  The  candidate  at  hospital  ex- 
amination who  would  neglect  to  mention  vomiting  as  a 
symptom  of  strangulated  hernia  would  get  a  black  mark. 

To  say  that  herniotomy  is  a  comparatively  easy  opera- 
tion might  surprise  one  who  has  never  tried  it,  and  who 
has  timidly  folded  his  knowledge  in  the  seven  anatomical 
layers.  Certain  drawbacks  are  naturally  to  be  expected, 
and  should  be  overcome  on  general  principles.  Living 
anatomy  has  a  way  sometimes  of  dodging  the  per- 
ceptions of  the  most  expert  operator.  In  herniotomy 
it  is  the  rule.  The  layers  are  always  ready  to  compro- 
mise their  individuality  under  a  becomingly  cautious  use 
of  the  director.     The  main  thing  to  be  sure  of  is  when 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


593 


the  sac  is  reached,  no  matter  whether  the  operator  di- 
vides six  or  six  times  six  layers  before  he  gets  to  it. 
And  sometimes  in  very  old  hernias  he  can  take  his 
choice. 

The  making  of  clean,  free  cuts,  and  always  in  the 
same  line,  invariably  gives  the  best  results.  As  a  rule  I 
prefer  to  open  the  sac,  as  I  believe  it  does  not  add 
to  the  gravity  of  the  operation,  while  it  insures  safety  in 
other  directions.  I  have  not  seen  a  case  in  which  I 'was 
willing  to  do  otherwise,  and  I  do  not  believe  I  have  lost 
one  in  consequence. 

Too  much  stress  cannot  be  laid  upon  the  necessity  of 
having  the  strangulated  portion  of  gut  in  the  best  possi- 
ble condition  before  returning  it  into  the  abdomen.  Time 
is  well  spent  in  such  endeavors.  Nothing  will  accomplish 
the  end  in  view  more  efficiently  than  the  direct  application 
of  towels  wrung  out  in  a  hot  antiseptic  solution.  I  have 
kept  a  suspicious  knuckle  of  gut  covered  by  turns  in  this 
way  for  nearly  an  hour,  with  the  result  of  a  perfect  res- 
toration of  the  circulation. 

In  the  treatment  of  this  as  well  as  any  other  operation 
wound,  the  indications  for  cleanliness,  drainage,  and  rest 
are  carefully  followed,  nothing  more.  I  have  never  be- 
lieved that  the  antiseptic  spray  was  necessary  for  a  good 
result  in  any  operation.  You  gain  every  bit  as  much, 
and  with  half  the  trouble,  by  thoroughly  irrigating  the 
wound  with  an  antiseptic  solution  after  the  operation  is 
completed.  Corrosive  sublimate  solution  (in  the  propor- 
tion of  I -1 500)  was  used  in  my  cases  in  this  way. 

I  do  not  think  it  is  a  calamity  for  a  herniotomy  wound 
not  to  heal  by  first  intention,  as  by  granulation  and  subse- 
quent cicatrization  the  hernial  opening  and  sac  are  more 
likely  to  become  occluded.  The  aim  is,  of  course,  for 
first  intention.  While  closing  the  wound,  and  after  in- 
serting a  decalcified  drainage-tube,  it  is  well  to  take 
several  deep  stitches  through  the  entire  substance  of  the 
sac  at  different  points,  with  the  chance  of  exciting  adhe- 
sive inflammation,  and  thus  obliterating  the  sac  cavity. 
I  succeeded  by  this  method  in  four  cases.  After  closing 
the  wound,  firm  pressure  is  maintained,  upon  a  warm, 
thick,  moistened  pad  of  sublimated  gauze,  by  means  of 
an  ordinary  spica  bandage.  The  dressings  are  not  dis- 
turbed as  long  as  the  temperature  is  normal,  or  until  the 
wound  is  healed. 

Partly  as  a  precautionary  measure  against  traumatic 
peritonitis,  but  principally  for  purpose  of  absolute  rest, 
my  patients  are  kept  under  the  influence  of  morphine 
during  the  first  four  or  five  days  after  the  operation.  The 
bowels  generally  take  care  of  themselves,  and  require  no 
help  unless  evidences  of  intestinal  irritation  manifest 
themselves.  One  of  the  cases  did  not  obtain  an  evacua- 
tion until  the  end  of  the  fourteenth  day,  and  made  no 
complaint  because  he  thought  it  was  natural  under  the 
circumstances* 

*  247  Lbxincton  Avenue. 


The  Antidote  Bag. — Mr.  Martindale,  of  London, 
who  was  the  first  to  adopt  a  suggestion  to  produce  a 
bag  fitted  with  every  remedy  and  appliance  likely  to  be 
needed  in  the  treatment  of  a  case  of  poisoning,  has  now 
further  improved  upon  it  by  omitting  some  articles,  as 
the  stomach-pump,  enema,  catheter,  etc.,  which  are  al- 
ways at  hand,  and  has  thus  not  only  rendered  the  bag 
more  portable,  but  has  been  enabled  to  supply  it  at  a 
greatly  reduced  cost.  This  smaller  bag  contains  the  fol- 
lowing antidotes,  which  are  labeled  with  directions  for 
their  use,  viz. :  dialysed  iron,  syrup  of  chloral,  chloroform, 
aromatic  spirit  of  ammonia,  spirit  of  chloroform,  oil  of 
turpentine,  acetic  acid,  tincture  of  digitalis,  nitrite  of 
amyl  c^p$ules,  sulphate  of  zinc,  ipecacuanha,  bromide 
of  potassium,  calcined  magnesia,  tannin,  and  a  hypoder- 
mic case  with  syringe  and  solutions  of  acetate  of  morphia, 
apomorphia,  nitrate  of  philocarpine,  sulphate  of  atropia, 
and  nitrate  of  strychnine. — London  Lancet^  September 
27,  1884. 


SOME  NEW  FACTS  AND  CONSIDERATIONS 
IN  THE  DIAGNOSIS  OF  CANCER  OF  THE 
STOMACH  AND  CANCER  OF  THE  PAN- 
CREAS. 

By  MIDDLETON  GOLDSMITH.  M.D., 

RUTLAND,  VT„ 
BRBVKT      LIKUTRN  A  NT-COLONEL        AND       SUKGBON,       POKMRKLY       PKOFBSSOR      OF 
SURGKRY  IN    CASTLETON   MEDICAL    COLLSGB,   AND    HONORAkY    MRMBSR  OP  TUB 
NBW  YORK  PATHOLOGICAL  SOCIKTY,   STC,  BTC. 

It  is  pretty  generally  and  well  agreed  that  the  diagnosis 
of  primary  cancer  of  the  pancreas  is  always  uncertain,  if 
indeed  it  is  ever  possible ;  or,  in  other  words,  there  are  no 
agreed-upon  signs  surely  diagnosing  primary  cancer  of 
the  pancreas.  About  the  sum  and  substance  of  what 
our  best  diagnosticians  lay  down  is  to  the  effect  that  a 
painful  tumor  in  the  epigastrium,  unattended  by  gastric 
derangement,  such  as  anorexia,  vomiting  of  coffee-ground 
like  ejecta,  or  even  bloodless  vomiting,  pain  after  eating, 
etc.,  may  be  set  down  as  cancer  of  the  pancreas. 

When  it  is  remembered  that  there  are  many  cases  of 
cancer  that  present  during  life  no  symptoms  of  gastric 
disturbance  and  no  signs  of  epigastric  tumor,  it  is  apparent 
that  the  foregoing  is  not  very  reliable  ;  and  still  further, 
when  it  is  remembered  that  a  cancer  of  the  pancreas  may 
exist  and  have  the  exact  symptoms  of  simple  stomach 
cancer  minus  only  the  hemorrhage,  the  physician  attempt- 
ing to  determine  as  between  cancer  of  the  pancreas  and 
cancer  of  the  pylorus  is  adrift  without  a  star  or  compass 
to  guide  him. 

Now,  it  so  happens  that  within  the  last  two  years  I 
have  met  with  three  cases,  one  of  cancer  of  the  stomach, 
which  had  but  one  certain  symptom  and  that  one  not 
laid  down  in  the  books  ;  and  also  two  cases  of  primary  can- 
cer of  the  pancreas,  both  of  which  had  a  symptom  by 
which  they  could  be  diagnosed. 

A  Mr.  B ,  a  butcher  by  occupation,  aged  between 

fifty  and  sixty  years,  for  more  than  a  year  had  been  ailing. 
About  two  months  before  his  death  he  consulted  me  on 
several  occasions.  His  appetite  was  pretty  uniformly 
good  ;  his  digestion  was  good  to  all  appearance ;  he  had 
no  pain  in  his  epigastrium;  he  had  no  coffee-ground 
vomiting,  and  indeed  had  vomited  but  once  in  six 
months.  There  was  no  tumor  in  the  epigastrium.  The 
abdomen  was  fiat,  collapsed  like  one  suffering  from 
chronic  diarrhoea,  and  flexible  all  over  save  that  at  the 
epigastrium,  and  for  a  hand's  breadth  below  the  ensiform 
cartilage,  the  abdominal  wall,  from  costal  margin  to 
costal  margin,  felt  like  a  concave  bridge  of  sole  leather 
and  unyielding  to  moderate  pressure.  Percussion  was 
not  dull  enough,  I  thought  at  the  time,  for  an  hypertro- 
phied  left  lobe  of  the  liver.  The  patienfs  face  had  the 
look  of  a  marked  cancerous  cachexia.  He  had  a 
peculiar  feior  to  his  eructations.  It  was  not  the  rotten- 
egg  odor — nor  the  odor  of  any  of  the  ordinary  fermenta- 
tions of  food,  but  the  odor  was  that  of  the  most  odorous 
uterine  cancer — once  smelled,  not  easily  forgotten.  I 
have  never  seen  this  symptom  mentioned.  It  is  not  a 
symptom  laid  down  in  the  books.  Fetor  of  the  breath  is 
often  mentioned,  but,  as  far  as  my  observation  has  gone, 
it  is  not  to  be  relied  upon.  A  bad  breath  is  so  common 
in  so  many  conditions  ;  it  comes  of  so  many  causes  ;  it 
is  so  inconstant  to  cancer,  apart  from  the  indigestion  it 
implies,  but  not  always  present  in  that  disease,  that  it 
cannot  be  justly  called  pathognomonic.  The  fetid  mat- 
ters in  the  breath  come  from  the  lungs,  bronchi,  pharynx, 
mouth,  or  teeth.  The  fetor  of  eructations  is  from  the 
contents  of  the  stomach.  A  stomach  whose  contents 
would  stink  when  opened  after  death,  barring  post-mor- 
tem putrefaction,  is  one  from  which  the  eructations  might 
be  supposed .  to  give  off  in  life  the  odors  of  the 
stomach  opened  after  death,  and  before  cadaveric  putre- 
faction. Besides,  the  kind  of  odor  is  cancerous  in  these 
cases,  not  putrefactive.  The  two  odors  are  different  and 
distinguishable.  To  smell  a  cancerous  womb  and  then 
a  putrefying  cadaver  is  to  learn  the  distinction. 

Inasmuch  as  many  cancerous  stomachs  opened  after 


594 


THE   MEDICAL  RECORD. 


[November  29, 1884. 


death  have  no  cancerous  odor,  so  many  and  a  large 
majority  of  those  having  cancer  during  life  have  not  fetid 
eructations.  Yet  when  the  eructations  have  that  canonical 
fetor,  that  fetor  is  pathognomonic.  From  these  considera- 
tions, cancer  of  the  stomach  was  the  best  guess  I  could 
make.  It  proved  to  be  correct  on  post-mortem.  The 
left  lobe  of  the  liver  had  become  adherent  at  some  time 
to  the  stomach,  and  had  been  drawn,  stretched  out  and 
thinned  by  the  stretching,  so  as  to  cover  the  whole  space 
mentioned  above  as  being  resistant  to  pressure.  On 
lifting  up  the  liver,  to  get  at  the  stomach  below,  I  tore 
the  softened  stomach  open  and  there  came  a  whiff  of  the 
odor  of  his  eructations,  an  odof  so  pungent  as  to  make  it 
necessary  for  some  of  us  to  change  our  clothes  before 
we  could  go  home  to  dinner.  It  was  a  simple  case 
of  soft  cancer  involving  the  greater  part  of  the  stomach, 
as  well  as  I  could  judge  from  a  very  brief  examination 
before  the  autopsy  was  surrendered  to  the  younger  folks 
then  and  there  present  The  microscope  proved  it  to  be 
encephaloid.  Now,  here  was  a  case  of  outrageous  gastric 
cancer  with  not  a  single  symptom  peculiar  to  it  «ave  one, 
which  attaches  not  so  much  to  the  organ  diseased  as 
the  putrefaction  of  the  matters  contained  in  it,  and 
that  not  one  of  the  symptoms  laid  down  by  authors. 
Nor  does  this  case  stand  alone.  I  remember  seeing  a 
cadaver  placed  on  table  for  examination  in  Louisville,  a 
good  many  years  ago,  in  which  the  diagnosis  had  been 
pernicious  anaemia,  the  case  having  not  shown  a  single 
symptom  belonging  to  cancer  of  the  stomach.  I  re- 
member the  surprise  with  which  the  cancer  of  the  stomach 
was  ^eeted.  There  afe  on  record  a  good  many  cases 
of  this  kind  besides  Abercrombie's  celebrated  one.  So 
that  it  may  be  said  there  are  in  some  cases  of  cancer  of 
the  stomach  no  stomach  symptoms  to  exclude. 

Of  the  two  cases  of  pancreatic  cancer,  the  first  was 
that  of  a  healthy-looking,  spare  little  woman  who  came  to 
me  from  Indiana  for  the  treatment  of  what  proved  to  be 
gall-stones.  She  had  the  usual  symptoms  which  attend 
upon  the  passage  of  gall-stones  from  the  gall-bladder,  as 
well  as  the  dark  urine  or  the  icterus  which  follow  it.  She 
was  one  of  the  few  persons  whom  I  have  met  in  whom 
the  projecting  gall-bladder  felt  like  a  bag  of  beans.  She 
passed  large  numbers  of  faceted  calculi  as  well  as  some 
crystallizing  and  jagged  specimens,  which  had  not  been 
long  residents  of  the  gall-bladder. 

Along  toward  what  seemed  to  be  the  approach  to  con- 
valesence  from  the  gall-stones,  the  appetite,  which  here- 
tofore had  been  good,  began  to  fail.  Her  pains,  which 
had  heretofore  been  at  intervals  (marking  the  passage  of 
gall-stones),  came  to  be  continuous  and  gradually  grew  to 
be  more  and  more  intolerable.  She  had  vomiting,  but 
there  was  no  blood  in  the  vomit,  she  had  an  intensely 
sour  stomach,  gastric  catarrh,  and  constipation.  There 
was  no  increase  of  the  stomach  pain  after  eating. 

Meanwhile  her  face  began  to  show  a  cachectic  look. 
About  this  time  I  thought  1  could  perceive  a  very  small 
hard  lump  a  little  below  the  pylorus  when  the  stomach 
was  not  full  of  food.  The  tumor  would  always  disappear 
after  eating  a  full  meal.  This  little  tumor  was  hard,  and 
somewhat  painful  to  the  touch.  It  was  fixed.  It  did  not 
ascend  or  descend,  or  otherwise  alter  its  position  as 
tumors  of  the  pylorus  do  sometimes.  All  the  while  the 
patient  kept  taking  opium  to  keep  the  pain  subdued. 
But  for  all  that  the  face,  besides  its  cancerous  suggestion, 
showed  that  cast  of  expression  whose  only  name  is  the 
cachexia  of  pain.  Then  came  a  curious  semi-delirium, 
with  a  far-off  look  which  I  have  seen  but  twice.  The 
most  careful  inquiry  elicited  no  signs  of  fatty  stools. 
There  could  be  found  no  tumor  of  the  liver,  no  disease 
of  any  other  portion  of  the  body  ;  there  were  no  glandu- 
lar enlargements.  So  that  I  was  compelled  to  the  diag- 
nosis of  primary  cancer  of  the  spleen  in  addition  to  gall- 
stones. 

After  death,  which  occurred  some  six  months  subse- 
quent to  the  discovery  of  the  little  neoplasm,  below  the 
pylorus,  we  found  the  liver  (save  a  number  of  gall-stones 


in  it)  and  the  abdominal  viscera  healthy.  There  was  no 
disease  of  the  stomach  save  extreme  atrophy,  and  the 
little  tumor  of  the  pancreas  proved,  under  the  micro- 
scope,  to  be  a  spindle-celled  carcinoma.    .     .     . 

The  third  case  was  that  of  a  Mrs.  H ,  living  at  that 

time  at  Factory  Point,  some  thirty  miles  from  Rutland 
I  saw  her  twice.  I  found  her  greatly  emaciated  and  quite 
feeble.  She  had  anorexia,  occasional  vomiting,  and  pain 
about  the  pylorus  after  eating.  She  stated  that  her  pains 
were  not  all  related  to  the  times  of  eating,  but  she  had 
other  and  greater  pains  during  the  ni^ht,  which  were  some- 
times relieved  by  changes  of  position,  but  would  often 
endure  all  night. 

When  I  first  felt  the  epigastrium,  she  being  recumbent, 
and  the  stomach  empty,  I  found  a  tumor  apparently  about 
as  big  as  a  pullet's  egg.  The  lump  was  round,  hard,  and 
to  the  touch  nodular.  It  was  painful  to  the  touch,  and 
seemingly  could  not  be  moved.  Of  that,  however,  I  wa« 
not  so  sure,  because  manipulation  hurt  her  so  much  I  did 
not  push  this  branch  of  the  inquiry.  I  did  not  see  the 
matters  vomited,  or  notice  the  drooling  her  doctor  after- 
ward told  me  about.  Her  attendant  had  noticed  nothing 
unusual  in  her  stools  or  vomit. 

At  my  next  visit  the  symptoms  were  unchanged,  except 
her  body  was  failing  and  na  tumor  could  be  felt  in  tkt 
epigastrium.  I  found  out  after  her  death  that  on  the 
morning  when  I  first  saw  her  she  had  eaten  nothing,  and 
that  at  my  last  visit  she  had  just  taken  her  usual  meal 
The  trains  would  arrive  at  Rutland  a  little  after  11  A.M., 
and  arrive  at  Factory  Point  a  little  after  12  m.,  so  that 
my  arrival  at  the  house — about  a  mile  from  the  railroad 
station — would  occur  commonly  about  a  quarter  past 
twelve  and  half-past  twelve — and  half- past  twelve  is  the 
canonical  dinner  hour  for  all  Vermont. 

The  following  is  a  history  of  the  CAse  from  Dr.  Wyman, 
of  Factory  Point,  who,  though  not  at  the  time  in  attend- 
ance, had  seen  of  her  more  than  her  later  physician : 

"  Last  April  she  first  consulted  me  in  regard  to  hernot 
being  well.  She  complained  of  a  neuralgic  or  rheumatic 
pain  in  the  left  side  under  the  short  ribs,  and  in  the  pit 
of  the  stomach.  She  had  no  appetite — guessed  she  was 
^  lazy,'  as  she  was  weak  and  tired.  I  prescribed  for  her 
two  or  three  times  during  the  month. 

*'  In  May  she  appeared  about  the  same,  only  the  pain  in 
the  side  was  at  times  worse.  She  had  spells  of  it  about 
10  o'clock  A.M.,  and  I  learned  her  nights  were  sleep- 
less, and  often  she  could  not  lie  down  on  account  of  the 
pain.  It  was  worse  three  or  four  hours  after  eating.  She 
looked  sallow  and  tired.  The  pain  was  dull  and  con- 
stant, at  times  more  severe.  It  would  start  in  the  left 
hypochondrium,  or  a  little  above,  and  extend  to  just 
below  the  ensiform  cartilage,  and  the  space  there  was 
tender  to  pressure.  She  complained  also  of  pain  under 
the  right  shoulder-blade.  Her  bowels  were  regular, 
urine  normal,  tongue  not  coated,  but  color  a  little 
too  dark,  but  not  purplish.  She  seemed  almost  like 
one  who  some  time  had  had  malaria  (she  lived  for 
two  or  three  years,  a  few  years  ago,  in  Central  New 
York),  and  I  thought,  perhaps,  there  was  some  remnant 
of  that  lurking  in  her  system.  So  she  continued,  not  very 
sick,  but  ailing,  growing  weaker  and  thinner ;  appetite 
fickle,  often  a  perfect  loathing  of  food ;  no  thirst,  and 
pains  about  the  same  until  the  middle  of  June,  when  she 
was  taken  worse  ;  pain  intense,  but  more  in  dorsal  region, 
but  alternating  between  that  and  side  and  stomach ;  quite 
a  relax  of  the  bowels,  constant  nausea,  and  once  or  twice 
she  vomited.  The  ejecta  was  simply  a  watery  fluid, 
slightly  tinged  yellow.  On  account  of  tlie  pain  in  the 
back  I  exs^mined  the  urine,  but  as  its  appearance  was  so 
natural  I  only  tested  it  for  sugar  and  albumen,  and  found 
none.  The  stools  she  described  as  being  like  those 
which  occur  in  simple  diarrhoea,  and  I  did  not  examine 
them,  as  I  could  not  ascertain  that  there  was  anything 
strange  about  them.  I  regret  now  that  I  did  not  see 
them. 

"  About  this  time  I  went  West,  leaving  the  case.    She 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


595 


had  grown  much  more  comfortable,  although  she  failed 
very  perceptibly  during  this  aeute  attack.  The  remedies 
which  I  left  for  her  will  give  you  a  key  to  my  diagnosis, 
viz, :  Creasote  in  one-tenth  drop  doses  and  arsenicum 
alb.,  although  a  careful  exanfiination  of  the  abdominal 
viscera  failed  to  find  any  tumor  or  swelling  of  any  kind, 
neither  any  tenderness  to  pressure  in  any  place  except 
over  the  coeliac  axis  or  plexus.  She  urged  me  while 
pressing  over  the  stomach  and  bowels  not  to  be  afraid  to 
use  as  much  force  as  I  wanted,  as  there  was  no  pain  result- 
ing. The  diarrhoea  lasted  but  a  day  or  two,  and  then  the 
bowels  moved  naturally  every,  or  every  other  day.  About 
ten  days  after  I  left  her  to  go  away  she  became  fearfully 
constipated.  Dr.  Trull  was  called,  and  as  he  attended 
the  case  thereafter  until  death  terminated  the  suffering, 
he  will  give  you  the  further  report. 

"  One  thing  I  often  noticed.  Beside  her  bed  she  had 
lying  upon  the  floor  a  piece  of  paper,  say  ten  or  twelve 
inches  square,  and  this  would  be  covered  with  a  thick, 
viscid,  and  sometimes  frothy  sputum.  She  did  not  cough 
it,  for  she  had  no  cough  ;  she  did  not  vomit  it,  for,  while 
under  my  care,  she  only  vomited  at  the  time  mentioned 
above.  She  just  seemed  to  *spit'  it  as  it  came  into  her 
mouth.  And  for  some  reason  she  seemed  remarkably 
shy  in  speaking  about  it.  Taking  your  tabulated  symp- 
toms of  diagnostic  points,  I  will  indicate  what  symptoms 
she  had  while  I  saw  her  professionally:  Emaciation 
rather  rapid,  but  not  extreme  ;  no  tumor  in  epigastrium  ; 
severe  pain  in  epigastrium,  side,  and  back ;  stools  de- 
scribed as  natural ;  no  sugar  in  urine  (I  mentioned  that 
I  tested  for  albumen,  but  found  none)  ;  impaired  appe- 
tite, disordered  digestion  ;  loathing  of  food ;  pain  worse 
three  or  four  hours  after  eating  (marked)  ;  vomiting  but 
the  time  mentioned.  She  had  then  anorexia,  debility, 
emaciation,  a  flow  of  saliva-like  fluid  from  the  mouth, 
coeliac  -neuralgia ;  dull,  heavy,  aching  pain  deep  down  in 
the  epigastric  region,  radiating  or  extending  to  the  back 
and  lumbar  region,  relieved  by  rubbing  and  assuming 
erect  position  or  sitting  up  in  bed ;  worse  by  paroxysms 
and  at  night ;  no  jaundice,  no  thirst,  no  increase  in  tem- 
perature, a  slightly  increased  pulse,  a  sallow,  but  not 
greenish-yellow  complexion  ;  urine  and  stools  natural,  so 
far  as  observed.  These  constitute  the  array  of  symptoms 
as  far  as  I  observed  them.  Their  change  Dr.  Trull  will 
notice.  The  family  history  revealed  a  cancerous  dia- 
thesis. Some  fourteen  years  ago  she  went  to  you  in 
Rutland,  and  you  removed  a  tumor  from  the  back  of  her 
hand.  Have  you  any  recollection  or  record  of  its  char- 
acter ?  The  large  gsJl-stone  which  was  found  in  the  gall- 
bladder I  send  you  by  mail  with  this.  Its  weight  was 
3  iss.  If  you  have  no  further  use  for  it  after  examining 
and  keeping  it  as  long  as  you  desire,  will  you  kindly  re- 
turn it  to  me  ? 

**  I  have  thus  hurriedly  tried  to  give  you  the  salient 
points  in  the  case.  If  I  have  failed  in  any  of  them  please 
interrogate  me  further.  Hoping  it  will  be  satisfactory, 
however,  I  am,  sincerely  yours,  E.  L.  Wyman." 

Now,  here  was  a  woman,  about  sixty  years  of  age  to 
appearance,  with  a  family  history  of  cancer,  with  a  cachectic 
look,  pale,  and  rapidly  emaciating,  with  more  or  less  con- 
stant pain  radiating  from  the  epigastrium,  having  occa- 
sional vomiting  and  anorexia,  and  an  increase  of  pain  a 
few  hours  after  eating,  and  a  tumor  at  the  epigastrium. 
Could  there  be  a  plainer  case  of  cancer  of  the  pylorus  ? 

Yet  the  post-mortem  examination  showed  it  to  be  a 
case  of  primary  cancer  of  the  pancreas,  with  dilatation  of 
the  stomachy  and  one  big  non-faceted  gall-stone  in  the 
gall-bladder. 

These  two  cases  are  worthy  of  comment,  for  in  the 
study  of  them  I  think  we  may  find  something  to  make  the 
diagnosis  of  this  confessedly  undiagnosable  disease  pos- 
sibly diagnosable. 

Dr.  Jenner  says,  in  effect,  no  symptoms  are  pathogno- 
monic of  pancreatic  disease.  Dr.  Wardell,  in  **  Reynolds' 
System  of  Medicine,"  vol.  iii.,  p.  428  :  "  Da  Costa  has 
professed  to  diagnose  cancer  of  the  pancreas  from  its 


other  maladies,  but  the  truth  is  we  have  no  just  rules  of 
observance  to  point  out  any  real  distinctions."  Da  Costa, 
in  his  "Medical  Diagnosis,"  p.  605,  says  ;  "As  regards 
cancer  (of  the  pancreas)  the  most  trustworthy  symptoms 
are  a  tumor  in  the  epigastric  region,  pain  in  the  back, 
not  increased  by  the  takmg  of  food,  but  usually  augmented 
by  the  erect  posture;  progressive  emaciation  and  de- 
bility; an  appetite  capricious  rather  than  diminished, 
and,  in  some  instances,  indeed  a  ravenous  desire  for 
food  ;  constipation  at  times,  but  far  from  invariably."  It 
seems  to  me  that  the  two  cases  of  primary  cancer  of  the 
pancreas  above  related  point  to  a  diagnostic  rule  of  great 
value,  so  far  as  two  cases  can  go  toward  making  a  rule. 
In  the  first  case  it  is  to  be  noticed  that  the  little  tumor 
could  be  felt  almost  all  the  while,  and  that  at  the  times 
at  which  it  could  not  be  felt  the  stomach  was  distended 
by  recently  eaten  food.  What  probably  made  it  possible 
to  feel  the  tumor  at  almost  any  time  or  any  posture  was  her 
emaciation,  and  the  small  quantity  of  food  in  her  stomach. 
The  post-mortem  examination,  in  disclosing  the  atrophy  of 
her  stomach,  accounts  for  the  fact  that  her  cancer  of  the 
pancreas  was  so  seldom  overlaid  by  that  viscus  distended. 
In  the  second  case  the  tumor  was  seldom  felt  during  life. 
Indeed  I  don't  think  it  was  felt  more  than  once.  When 
it  was  felt  she  was  recumbent^  and  had  not  been  eating. 
The  post-mortem  in  revealing  a  very  considerable  disten- 
tion of  the  stomach,  revealed  the  reason  why,  and  how 
the  cancer  of  the  pancreas  was  aproned  over  most  times 
during  life. 

Cancer  of  the  pylorus  sometimes  appears  and  disap- 
pears ;  I  saw  one  such  a  case  a  few  years  ago.  A  man, 
from  Salem,  N.  Y.,  came  to  see  me  on  account  of  a 
stomach  trouble  which  had  been  pronounced  cancer. 
On  examination  of  him,  as  he  lay  on  my  operating-table, 
I  could  feel  no  tumor  at  the  epigastrium,  and  I  was  inclined 
to  doubt  the  diagnosis  of  his  former  attendant,  whom  I 
knew  very  well,  and  knew  to  be  a  practitioner  of  con- 
siderable ability.  I  bethought  me  to  make  the  patient 
stand  up.  In  an  instant  the  pyloric  tumor  was  there  as 
plain  as  a  pike-staff.  I  wrote  to  his  attending  physician 
and  asked  him  to  follow  the  case  and  get  a  post-mortem 
if  he  could.  He  did,  and  answered  that  the  case  was  one 
oi  cancer  of  the  pylorus,  not  of  the  pancreas.  But  it  ap- 
pears that  the  erect  posture  brought  the  pyloric  tumor 
within  the  region  of  touch,  and  in  doing  so  would  not 
have  uncovered,  but  rather  hidden  a  pancreatic  cancer. 

Hence,  in  examining  a  suspected  pyloric  tumor,  the 
fact  that  it  cannot  be  felt  in  conditions  which  allow 
the  stomach  to  get  over  it,  and  can  be  felt  only  when 
the  stomach  cannot  get  in  front  of  it  so  as  to  apron  it ; 
or,  in  other  words,  if  the  suspected  tumor  can  always 
be  felt  when  the  stomach  is  empty,  but  disappears 
whenever  the  stomach  is  distended,  and  if  the  tumor 
commonly  is  more  obvious  in  the  recumbent  than  in 
the  erect  posture,  I  feel  quite  confident  we  should  be 
justified  in  making  the  diagnosis  of  pancreatic  tumor  even 
in  the  presence  of  some  of  the  symptoms  of  stomach 
cancer,  such  as  anorexia,  pain  after  eating,  or  occa- 
sional bloodless  vomits.  Another  diagnostic  point  which 
seems  to  me  as  of  considerable  value  is  the  character  of 
the  pain  as  well  as  its  persistence.  In  the  first  place, 
the  pain  is  more  continuous  than  in  cancer  of  the  pylorus. 
In  the  second  place,  the  pain  radiates  in  more  directions 
than  in  cancer  of  the  pylorus.  In  the  third  place,  the 
pain  is  more  dismal,  more  dolorous.  It  is  a  pain  that 
seemingly  has  no  ending.  It  is  a  disheartening  pain.  It 
does  not  become  more  endurable  by  having  been  en- 
dured.    It  is  a  pain  which  has  no  leaven  of  hope  in  it. 

It  will  be  noticed  in  Mrs.  H 's  case  that  there  was 

pretty  constant  (for  a  time)  spitting  of  a  saliva-like  fluid 
from  the  mouth.  Frerichs  attributes  to  this  symptom 
considerable  importance,  but  says,  **  We  must  be  careful 
in  considering  such  an  increased  salivary  secretion  as  due 
to  disease  of  the  pancreas,  for  as  yet  there  are  no  re- 
corded cases  of  primary  uncomplicated  pancreas  disease 
in  which  this  symptom  was  definitely  present "  (Fried- 


596 


THE  MEDICAL  RECORD. 


[November  29,  1884. 


reich,  in  "Ziemssen's  Cyclopaedia,"  vol.  viii.,  p.  567, 
to  whom  I  must  refer  the  reader  for  further  consideration 
of  the  value  of  this  symptom). 

P.S. — The  writer  is  not  unaware  of  the  extreme  rarity 
of  primary  cancer  of  the  pancreas.  Dr.  Putnam,  of  this 
place,  saw  the  first  case  with  me,  and  attended  the  post- 
mortem. The  other  case  was  witnessed  by  Drs.  Trull, 
Wyman,  and  others,  I  think,  at  Pactory  Point,  Vt. 


JEQUIRITY   OPHTHALMIA.* 
By  JOSEPH  A.  ANDREWS,  M.D., 

OPHTHALMIC  SI/KGBON  TO  CHARITY  HOSPITAL,   NKW  YORK. 

Having  quite  recently '  considered,  at  some  length,  the 
subject  of  jequirity  ophthalmia,  I  desire  here  to  limit 
my  remarks  to  a  brief  review  of  certain  papers  that  have 
appeared  on  the  subject  in  question  since  my  own  com- 
munication alluded  to  above  was  published. 

First,  is  jequirity  directly  responsible  for  the  disas- 
trous results  which  have  been  placed  on  record  as  having 
followed  its  use  ? 

Has  it  a  constant  and  regular  action,  and  are  there  any 
dangers  to  be  apprehended  from  its  employment,  even 
according  to  the  directions  which  I  have  indicated  in  my 
paper  (loc.  cit.,  p.  251)? 

In  order  to  answer  the  first  question,  it  will  be  neces- 
sary to  examine  the  evidence  which  has  been  adduced  to 
show  that  jequirity  is  to  blame  for  the  mischief  to  the  eye 
which  has  resulted  during  its  use. 

Jacobson  •  records  a  case  in  which  jequirity  produced 
purulent  infiltration  of  the  cornea,  perforation  of  the  lat- 
ter, and  exposure  of  the  entire  iris.  This  would  certainly 
seem  to  be  a  grave  reproach  to  the  use  of  the  remedy  in 
question.  In  this  particular  case,  the  ophthalmia  pro- 
duced was  certainly  not  true  jequirity  ophthalmia,  and 
yet  this  circumstance  would  not  be  a  sufficient  defence 
of  the  remedy ;  but  I  am  convinced  that  the  real  source 
of  mischief  is  to  be  sought  in  the  strength  of  the  infusion 
and  the  manner  in  which  it  was  employed,  Jacobson 
having,  namely,  instilUd  the  infusion  (five  per  cent.)  into 
the  conjunctival  sac,  and  kept  up  the  action  of  the  drug 
with  compresses  wet  with  the  infusion.  This  was  follow- 
ing Dr.  de  Wecker's  first  instructions  regarding  the  use  of 
jequirity  to  the  letter ;  and  that  Dr.  de  Wecker  obtained 
uniformly  favorable  results  before  he  had  modified  his 
manner  of  applying  the  drug,  is  certainly  very  remarkable 
and  providential.  But  in  Dr.  Knapp's  two  cases,*  al- 
though true  jequirity  ophthalmia  was  not  produced,  a 
violent  pyorrhoea  having  followed  the  use  of  the  infusion, 
and  affected  the  other  not  inoculated  eye,  nevertheless 
this  case  is  a  most  instructive  one.  Dr.  Knapp  treated 
the  two  cases  in  question  according  to  Dr.  de  Wecker's  last 
directions,  making  a  single  brushing  of  a  fresh  three  per 
cent,  solution,  macerated  for  three  hours,  over  the  entire 
upper  lid ;  and  yet  this  single  application  was  followed 
by  violent  reaction  and  perforation  of  the  cornea.  If  it 
be  possible  with  jequirity  to  produce  a  purulent  oph- 
thalmia, then  we  cannot  defend  the  remedy  in  a  given 
case  in  which  it  has  produced  mischief  by  the  substitution 
of  a  purulent  for  a  genuine  jequirity  ophthalmia.  Never- 
theless, I  confidently  believe  that  the  dangers  to  be  ap- 
prehended from  the  drug  may,  in  a  very  marked  degree, 
be  avoided  by  observing  the  strictest  caution  in  its  use. 
The  facts  which  should  be  seriously  borne  in  mind  are, 
that  all  eyes  are  not  afiected  in  the  same  degree  by  the 
remedy,  a  three  per  cent,  infusion  in  one  instance  being 
followed  by  violent  reaction,  while  in  others  a  stronger 
infusion  may  ^ve  rise  only  to  slight  reaction.  Therefore 
I  believe  that  the  safest  plan  to  observe  is  to  begin  with 
a  weak  solution,  say  two  per  cent.,  even  where  there  is 

1  Read  before  the  American  Ophthalmological  Sociecjr,  1884. 

*  Trachoma  and  the  Etiology  of  Jequirity  Ophthalmia.  Archives  of  Medicine, 
vol.  xi.,  No.  3,  iJp.  321-261,  June,  1884. 

'  Herliner  klinische  Wochenschrift  No.  17,  April  28,  1884,  p.  258. 

*  Archives  of  Ophthalmology,  vol.  xlii.,  No.  i. 


pannus,  and  one  per  cent,  when  the  cornea  is  not  in- 
volved, and  keep  in  mind  the  fact  that  there  is  a  period 
of  incubation  which  may  exceed  twenty-four  hours.  The 
berries  should  be  husked,  crushed,  and  macerated  far  about 
six  hours  in  cold  distilled  Ivaier,  then  filtered;  and  after 
a  single  thorough  brushing  of  the  palpebral  conjunctiva 
with  cotton  wrapped  about  the  end  of  a  match.  Thirty 
hours  are  allowed  to  elapse  before  renewing  the  brushing ; 
then,  according  to  the  susceptibility  of  the  patient  to  the 
action  of  the  remedy,  we  may  repeat  one,  two,  or  three 
times  daily,  always  proceeding  with  caution,  and  never  keep 
up  the  action  of  the  drug  with  compresses  wet  in  the  infu- 
sion. By  following  these  directions  I  have  never  yet 
seen  an  untoward  result,  and  I  have  used  the  remedy  in 
one  hundred  and  forty  cases  of  diseases  of  the  cornea  and 
conjunctiva. 

Pre-existing  purulence  is  a  positive  contra-indication  to 
the  use  of  jequirity.  Papillary  hypertrophy  of  the  con- 
junctiva is  not  favorably  influenced  by  the  remedy. 
Hippel  says,  the  more  hyperaemic  the  conjunctiva  is,  the 
more  intense  will  be  the  reaction.  De  Wecker  says  this 
is  an  error  ;  but  from  my  own  observations  I  feel  disposed 
to  believe  that  Hippel's  statement  is,  in  a  measure,  cor- 
rect. However,  this  much  is  true ;  the  nearer  the  con- 
junctiva approaches  a  normal  physiological  condition,  the 
more  certain  and  intense  will  be  the  impression  produced 
by  the  infusion.  The  most  violent  reaction  I  have  seen 
follow  the  use  of  an  infusion  of  jequirity  occurred  in  a 
case  of  sclerosis  of  the  cornea,  in  which  the  conjunctiva, 
for  all  practical  purposes,  was  normal.  But  the  patient 
in  this  instance  took  upon  herself  the  responsibility  of 
departing  from  my  instructions,  and  instead  of  a  single 
application,  and  awaiting  the  lapse  of  the  number  of  hoars 
indicated,  s\iQ  poured  i\ie  infusion  (three  per  cent.,  cold, 
macerated  for  six  hours)  into  the  eye  four  times  during 
the  day.  The  result  was  a  most  intense  chemosis  and 
swelling  of  the  lids  and  corresponding  side  of  the  face, 
and  nasal  mucous  membrane  ;  and  in  the  region  of  the 
frontal  sinus  the  pain  was  so  violent  that  the  patient  de- 
clared that  she  did  not  sleep  for  three  nights  ;  and  I  am 
convinced  that  her  suffering  must  have  been  very  acute.  \ 

With  violent  inflammatory  reaction  there  was  extensive 
formation  of  a  croupo-diphtheroid  membrane,  and  a  re- 
sulting symblepharon,  and  what  is  most  instructive  for  us 
to  remember  is  the  circumstance  that  it  was  a  case  of 
genuine  jequirity  ophthalmia,  no  purulence  having  oc- 
curred at  any  time  in  the  course  of  the  inflammation. 
And  yet  the  vision  was  improved  from  an  ability  to  per- 
ceive light,  to  counting  Angers  at  fifteen  feet. 

Dr.  de  Wecker  says,*  "  without  any  doubt,  the  cornea  is 
not  exposed  to  any  danger''  in  jequirity  ophthalmia. 
But  the  first  case  in  which  I  employed  the  remedy  taught 
me  that  this  was  a  most  pernicious  error,  and  that  the 
cornea  is  endangered.  However,  if  we  compare  the 
number  of  authors  who  have  declared  themselves  for  and 
against  the  jequirity  treatment,  we  find  that  the  former 
are  conspicuously  predominant,  and  it  would  seem  that 
those  authors  who  do  not  favor  the  remedy,  such  as  Vos- 
sius,  Galezowski,  and  Nicolini,  might  change  their  views 
if  their  experience  were  extended  to  a  larger  number  of 
selected  cases. 

Scrofulous  pannus  and  sclerosis  of  the  cornea  are  favor- 
ably influenced  by  jequirity,  and  I  have  had  very  gratifying 
results  in  this  class  of  cases  in  improving  the  vision  ;  but 
I  have  never  used  the  remedy,  as  Dr.  Wecker  has,  in 
torpid  ulcers  of  the  cornea,  firstly,  because  I  could  not 
satisfy  myself  that  the  cornea  was  not  placed  in  still 
greater  danger  by  its  use  ;  and  secondly,  I  felt  that  I  could 
rely  on  safer  and  really  more  satisfactory  means.  How- 
ever, of  course,  mere  conjecture  should  not  be  permitted 
to  weigh  against  the  results  of  experience,  and  Pr.  de 
Wecker's  experience  seems  to  speak  in  favor  of  the  rem- 
edy in  this  class  of  cases. 

40  West  Twbnty-fourth  Strbet. 

>  Graefe*s  Aichiv  ftlr  Oph.,  Bd.  xxx.,  A.  i.,  p.  367. 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


597 


New  Treatment  of  Strangulated  HiCMORRHoms. 
— Dr.  Monod  advises  a  new  treatment  for  strangulated 
haemorrhoids,  which  he  has  practised  with  great  success. 
It  consists  in  forcibly  dilating  the  anus,  as  in  case  of  fis- 
sure. Verneuil  had  already  recommended  this  method 
for  the  cure  of  simple  piles,  and  has  been  followed  by 
most  of  the  young  surgeons,  who  have  entirely  abandoned 
every  other  treatment.  To  effect  the  dilatation  Verneuil 
employed  specula  of  different  dimensions,  and  only  in  the 
case,  as  has  been  just  stated,  of  the  ordinary  condition 
of  haemorrhoids.  On  the  contrary,  he  says  that  •*  when 
the  piles  are  the  seat  of  sphacelus  he  always  waited  until 
the  complication  disappeared."  Monod,  who  has  imi- 
tated Verneuil  with  the  best  results  in  those  simple  cases, 
goes  still  farther,  and  instead  of  regarding  strangulation 
as  a  counter-indication  to  the  operation,  considers  that 
his  fact  renders  it  the  more  necessary.  He  cites  a  case 
n  point  He  was  called  by  one  of  his  confrh^es  to  see  a 
gentleman  who  had  been  suffering  excruciating  agony 
for  two  days  from  strangulated  piles,  and  on  whom  ice 
fomentations,  narcotics  inius  and  eoUra  were  tried  with- 
out effect.  Local  examination  showed  no  more  than  is 
ordinary  in  such  cases — a  ring  of  tumefied  external  haemor- 
rhoids surrounding  a  packet  of  internal  turgescent  haem- 
orrhoids, with  a  dark  spot  in  the  centre,  announcing  the 
commencement  of  sphacelus.  The  least  touch  was  pain- 
ful, and  the  patient  demanded  relief  at  any  price.  Par- 
tisan of  the  treatment  of  haemorrhoids  in  general  by 
dilatation,  he  thought  that  he  would  be  doing  right  in 
employing  it  in  the  present  case,  knowing  that  by  sup- 
pressing the  action  of  the  sphincter  the  pain  would  cease. 
Accordmgly,  the  patient  was  put  under  the  influence  of 
chloroform,  and  the  hemorrhoidal  tumors  reduced,  and 
then  Monod  largely  dilated  the  anus  with  his  fingers.  A 
few  minutes  afterward  the  patient  awoke  free  from  all 
pain,  and  in  a  few  days  he  had  the  satisfaction  of  not 
only  feeling  that  the  strangulation  had  entirely  disap- 
peared, but  that  he  was  for  ever  quit  of  his  piles.  This 
case  of  Monod^s  proves  that  the  hand  dilates  just  as  well 
as  the  speculum,  and  consequently  the  operation  is  re- 
duced to  its  simplest  expression. — Medical  Press^  Sep- 
tember 24,  1884. 

Naphthaline  in  Diarrhcea  and  Cystitis. — For  the 
last  three  years  Professor  Rossbach,  of  Jena,  has  em- 
ployed naphthaline  in  all  the  cases  of  diarrhoea  that  have 
come  under  his  care.  He  concludes  that  it  is  of  great 
service  in  all  cases  of  chronic  intestinal  catarrh,  with  or 
without  ulceration,  attended  by  chronic  diarrhoea,  and  in 
all  cases  the  stools  in  the  course  of  from  five  to  fifteen 
days  become  of  normal  frequency  and  consistence.  Some 
of  the  naphthaline  given  passes  over  into  the  urine,  and 
the  e£fect  in  the  case  of  urinary  troubles  was  noted  to  be 
exceedingly  favorable.  Pus,  blood,  and  vibriones  quickly 
disappeared  from  the  urine  after  its  administration.  It 
was  given  in  doses  of  thirty  to  forty-five  grains  per  day. 
After  half  a  grain  daily  the  appetite  was  often  improved. 
--The  Medical  Press^  October  15,  1884. 

Migraine  and  Tabes. — ^Among  the  various  prodro- 
mal symptoms  of  tabes  dorsalis,  attention  was  drawn 
by  Duchenne,  and  later  by  Pierret,  to  the  occurrence  of 
neuralgic  seizures  closely  simulating  hemicrania.  The 
recent  brochure  of  Berger  mentioned  this  fact  as  a  novel 
observation.  Dr.  H.  Oppenheim,  of  the  Berlin  Charity, 
points  out  (BerL  Klin.  Wochenschr,,  No.  38,  1884)  the 
priority  of  the  French  authors,  and  supplies  some  inter- 
esting details  of  twelve  cases,  from  a  total  of  eighty-five 
tabetics,  who  either  were  at  the  time  of  observation  or 
had  previously  been  subject  to  migraine,  ten  of  the  pa- 
tients being  females.  The  study  of  these  cases  leads  him 
to  conclude  that  hemicrania  is  far  too  frequent  a  feature 
in  the  history  of  tabes  dorsalis  to  be  considered  an  acci- 
dental event,  and  that  it  is  far  more  common  among 


tabetic  women — e.g.^  ten  times  in  thirty-two  cases — than 
among  men.  The  relations  which  the  hemicrania  bears 
to  tabes  are  various.  Generally  it  has  been  present 
many  years  before  the  initial  symptoms  of  tabes,  and  the 
hemicranial  attacks  increase  in  frequency,  intensity,  and 
duration  as  the  disease  advances.  Or  the  migraine  may 
coincide  with  the  onset  of  declared  tabetic  symptoms,  or 
be  associated  with  vomiting  and  gastric  crises.  In  rare 
cases  the  hemicrania  does  not  appear  until  tabes  is 
developed.  On  these  grounds,  Oppenheim  thinks  it  the 
duty  of  the  physician,  especially  in  migraine  of  increasing 
severity,  to  be  on  the  alert  for  the  recognized  early  symp- 
toms of  tabes-— especially  the  absence  of  knee-jerk. 

Tonsillotomy. — Dr.  de  Saint-Germain,  believes  that 
the  tonsillitome  of  Velpeau,  also  of  Luer,  are  very  un- 
satisfactory instruments,  and  better  not  used.  The  op- 
eration is  frequently  mcomplete,  and  the  tonsils  are  often 
left  untouched.  The  best  method  is  removal  by  means 
of  a  straight  bistoury.  The  tonsils  should  be  held  firm 
in  a  pair  of  forceps.  An  incision  made  close  to  the 
edges  of  the  instrument  by  means  of  a  bistoury  removes 
the  entire  tonsil  without  any  danger  of  injuring  either 
the  palate  or  the  pillars.  When  the  right  tonsil  is  re- 
moved, the  left  hand  must  perform  the  operation,  which 
is  decidedly  inconvenient.  Amygdalotomy  thus  per- 
formed on  children  is  never  followed  by  accidents,  nor 
by  hemorrhage  of  an  alarming  nature.  The  author  men- 
tions instances  where  excision  of  the  tonsils  among 
adults  provoked  hemorrhage,  which  resulted  in  the  death 
of  the  patient.  In  young  girls,  fourteen  or  fifteen  years 
of  age,  who  have  not  menstruated,  the  tonsils  ought  not 
to  be  removed ;  the  hypertrophy  frequently  disappears 
after  the  menses  appear.  Dr.  de  Saint-Germain  affirms 
that  the  tonsils  ought  not  to  be  removed,  unless  by  their 
size  they  impede  free  breathing. 

The  Symptomatic  Treatment  of  Typhoid  Fever. 
— Professor  Ebstein  read  a  paper  on  "  The  Treatment 
of  Typhoid  Fever,"  at  the  recent  meeting  of  the  German 
Scientific  Association,  at  Magdeburg.  He  gave  his  ex- 
perience for  the  past  seven  and  a  half  years,  at  the  Clinic, 
in  Holstein.  The  number  of  cases  treated  was  235. 
The  mortality  was  only  5.5  per  cent.,  reduced  to  2.5  per 
cent,  by  the  exclusion  of  inevitably  fatal  cases.  The 
author  concludes  that  the  so-called  ** abortive  treatment" 
with  calomel  is  useful  and  to  be  recommended.  In  the 
absence  of  any  causal  treatment,  this  can  only  be  symp- 
tomatic, i.e.y  measures  based  on  a  consideration  of  the 
morbid  phenomena  and  individual  conditions.  Above 
all,  attention  must  be  paid  to  judicious  dietetic  treatment 
and  the  maintenance  of  the  nutrition  of  the  patient.  The 
control  of  high  temperatures,  even  if  of  long  duration,  is 
only  called  for  when  they  are  associated  with  severe  car- 
diac or  nerve  symptoms,  or  when  the  temperature  attains 
such  a  height  as  to  threaten  life.  The  principles  of 
treatment  enunciated  are,  says  Ebstein,  far  more  satis- 
factory in  practice  and  in  their  results  than  an  exclusive 
adoption  of  "bath  treatment,"  or  other  methods  of  strict 
antipyresis.  Baths  he  regards  as  of  value  for  their  pow- 
erful stimulant  action,  and  he  would  employ  them  where 
other  methods  seem  to  be  insufficient. — London  Lancet^ 
October  18,  1884. 

The  Germ-Theory  of  Malaria. — In  a  paper  read 
by  Dr.  Hart,  of  Arkansas,  before  the  Medical  Society  of 
his  State  (Gaillards  Medical  Journal^  September,  1884), 
he  asks  some  rather  pertinent  questions  of  the  believers 
in  the  bacillus  malariae.  He  wishes  to  be  enlightened 
on  the  following  points :  i.  How  does  the  bacillus 
malariae  generate,  thrive,  and  prosper  under  such  diverse 
circumstances  and  surroundings  ?  2.  How  can  it  mani- 
fest itself  in  such  diversified  effects,  and  produce  so  many 
different  diseases  ?  3.  Will  not  the  §ame  pathogenetic 
cause  always  produce  the  same  disease  as  its  effect  ?  4. 
Will  different  bacilli  produce  the  same  diseases  ?  5.  It 
will  not  do  to  invoke  the  aid  of  any  other  bacillus  to  do 
the  work  of  the  malarial  bacillus,  though  the  existence  of 


598 


THE  MEDICAL  RECORD. 


[November  29,  1884. 


fifty  or  a  thousand  others  be  proven.  6.  If  there  be  a 
bacillus  malariae,  and  quinine  be  its  destroyer  or  germi- 
cide, why  is  it  not  equally  effective  and  potent  in  all  dis- 
eases produced  by  it  ?  7.  To  determine  the  existence 
of  a  malarial  bacillus  three  propositions  must  be  proven 
and  established;  First,  it  must  be  discovered;  second, 
it  must  be  cultivated ;  third,  it  must  be  capable  of  being 
reproduced.  8.  The  existence  of  a  germ  determined  and 
established  as  above,  three  propositions  must  be  proven 
to  establish  its  causative  relation  to  malarial  disease : 
First,  that  it  will  always  produce  the  same  disease  and 
nothing  besides  ;  second,  that  nothing  else  will  produce 
it ;  third,  that  malarial  disease  will  always  be  produced 
by  it  and  nothing  else.  The  above  propositions,  he 
concludes,  must  be  proven  to  a  demonstration  to  estab- 
lish the  existence  and  causative  relation  of  germs  to 
malarial  disease,  and  without  this  proof  palmella  spores 
and  algae,  and  pyrogen  and  pigmentary  elements,  and  all 
the  bacillus  twaddle  of  germ  theorists,  amounts  to  nought, 
and  is  but  fit  rubbish  for  the  waste-basket. 

The  Rbmoval  of  Tattoo  Marks. — India-ink  mark- 
ings in  the  skin  are  often  the  source  of  much  annoyance 
in  after  life  to  those  who  have  been  tattooed  in  youth. 
The  editor  of  the  Medical  Press  states  that  nothing  but 
the  knife  or  an  active  escharotic  will  produce  a  satis- 
factory result.  He  holds  that  the  cutis  must  be  de- 
stroyed. Dr.  Neale,  of  London,  however,  claims  that 
he  has  secured  good  results  with  sodii  ethylas,  first  sug- 
gested by  Dr.  B.  W.  Richardson.  He  cites  the  case  of  a 
gentleman  who,  in  his  younger  days,  had  a  palm  tree 
tattooed  on  his  arm  and  an  elaborate  bracelet  on  his 
wrist,  who  has  quite  lost  all  the  dark  matter,  etc.,  the 
skin  being  left  in  many  places  quite  natural,  although,  of 
course,  there  is  still  more  or  less  of  a  scar,  but  this 
diminishes  month  by  month. 

Resorption  of  a  Pleuritic  Effusion  following 
Erysipelas  of  the  Chest. — Dr.  M.  Schmidt  relates  the 
case  of  a  strong  man,  fifty-five  years  of  age,  who  was  ad- 
mitted to  hospital  suffering  from  pleurisy  with  efifusion. 
He  was  treated  by  poultices  to  the  chest  and  opium  in- 
ternally, and  subsequently  by  the  application  of  a  large 
blister.  No  improvement  followec^  but  about  a  week 
later  the  temperature  suddenly  ran  up  and  an  erysipelas 
began,  starting  from  the  wound  of  the  blister,  and  soon 
spreading  to  the  entire  surface  of  the  chest  both  front 
and  back.  Four  days  subsequently  it  was  found  that  the 
effusion  had  almost  entirely  disappeared.  The  erysipelas 
attacked  the  head  but  finally  yielded  and  the  patient 
made  a  good  recovery.  The  author  does  not  advocate 
Fehleysen's  practice  of  inoculating  the  patient  with  ery- 
sipelas in  order  to  promote  absorption  of  the  fluid,  as 
one  death  has  been  thus  caused.  But  he  thinks  that  by 
means  of  Pasteur's  method  of  culture  and  attenuation  it 
might  be  possible  to  obtain  a  modified  virus  which  could 
be  inoculated  with  entire  safety.  —  L  Union  Medicate^ 
September  25,  1884. 

Ephemeral  Rheumatismal  Periostitis. — At  the  re- 
cent meeting  of  the  French  Association  for  the  Advance- 
ment of  Science  at  Blois  i^V Union  M^dicaUy  No.  133, 
1884),  Professor  Verneuil  read  a  paper  on  an  affection 
not  hitherto  described  in  the  text-books,  but  of  which  he 
had  observed  two  examples.  The  disease  presents  under 
the  form  of  a  tumefaction,  hard  at  first,  but  becoming 
elastic  and  soft  after  a  certain  time.  At  one  period  the 
sense  of  fluctuation  was  so  marked  that  it  was  thought 
that  pus  was  present,  but  the  fluctuation  disappeared 
and  the  swelling  gradually  subsided.  There  was  no 
hyperplasia  as  in  ordinary  surgical  periostitis,  no  fever, 
and  no  discoloration  of  the  skin.  At  certain  points 
the  swelling  disappeared  spontaneously,  at  others  it 
at  first  diminished  and  then  increased  again  in  size. 
There  was  in  the*  latter  case  a  very  appreciable  con- 
gestive element,  for  one  of  the  patients  having  taken 
cold,  a  tumor  situated  on  his  face  increased  suddenly  to 
twice  its  former  volume.    There  was  no  previous  history  of 


syphilis,  but  the  patients  had  repeatedly  had  rheumatbm. 
As  usually  happens  when  cases  are  related  of  previously 
undescribed  conditions,  many  of  the  members  present 
had  seen  similar  cases,  and  they  related  the  histories  of 
their  several  patients,  which  agreed  in  general  with  those 
described  by  the  author  of  the  paper.  Professor  Verneuil 
proposed  to  call  the  affection  ephemeral  rheumatismal 
periostitis. 

Palliation  of  Epilepsy  by  Apomorphia. — It  is  stated 
in  the  Revue  Medicale  of  September  20,  1884,  that  a 
German  physician  has  succeeded  in  cutting  short  epileptic 
attacks  by  subcutaneous  injections  of  muriate  of  apomor- 
phia. He  injected  three  or  four  drops  of  a  one  per  cent 
solution.  The  patients  experienced  some  nausea  but 
there  was  no  vomiting.  Whenever  the  injection  was 
made  during  the  aura  the  impending  convulsion  was 
nearly  or  entirely  averted,  and  the  more  prolonged  the 
aura  usually  was,  the  more  pronounced  was  the  success 
of  the  injections. 

Decoction  of  Valerian  in  the  Treatment  of  Con- 
tusions.— Upon  the  suggestion  of  Dr.  Grehant,  Dr.  Ara- 
gon  has  made  a  ntimber  of  trials  to  determine  the  value  erf 
a  decoction  of  valerian  root  as  a  dressing  for  woundsy  and 
especially  for  contused  wounds.  The  decoction  used  was  of 
the  strength  of  thirty  grammes  of  valerian  root  to  one  litre 
of  water.  The  cure  was  no  more  rapid  than  that  which 
obtains  with  other  dressings,  but  from  the  first  application 
the  pain  was  completely  abolished.  This  is  a  point  of 
considerable  importance  if  it  should  prove  to  be  sustained 
in  further  trials. — Lyon  Midieal,  September  21,  1884. 

Treatment  of  Elephantiasis  by  Electricity.-- 
Dr.  Vicira  de  Mello  has  recently  published  a  monograph 
on  this  affection,  based  upon  the  study  of  upward  of  one 
hundred  and  fifty  cases.  He  shows  that  the  causes  capap 
ble  of  producing  lymphangitis  are  also  the  causes  of  ele- 
phantiasis, since  the  latter  is  developed  in  consequence 
of  successive  attacks  of  lymphangitis.  This  accounts 
also  for  the  comparative  frequency  of  the  aflfection  in 
warm  countries  where  the  causes  of  external  irritation 
are  so  numerous.  During  the  attacks  of  Ijrmphangitis 
the  lymph  transudes  into  the  subcutaneous  tissues,  and 
is  not  there  absorbed.  The  surrounding  parts  are  chron- 
ically inflamed,  proliferation  takes  place,  and  after  sev- 
eral successive  attacks  of  this  nature  the  elephantiasis 
becomes  established.  Death  from  elephantiasis  is  of 
very  exceptional  occurrence,  due  to  abscess  or  some 
other  complication.  The  author  has  never  observed  the 
termination  by  gangrene,  as  is  mentioned  by  some  pa- 
thologists. The  attacks  of  lymphangitis  are  usually 
treated  by  the  administration  of  quinine  in  large  doses, 
purgatives,  and  locally  by  antiseptic  applications.  Bat 
Dr.  de  Mello  asserts  that  the  only  method  of  treatment 
which  has  given  any  satisfaction  in  elephantiasis  is  that 
by  electricity.  He  has  employed  both  galvanic  and  fara- 
dic  electricity  with  excellent  results,  and  in  this  his  ex- 
perience is  in  accord  with  that  of  Drs.  Silva  Aranjo  and 
lA.OTMCort^,— Journal  de  Medicine  de  PariSfOctoheT  4, 1884. 

How  TO  Shrink  Hypertrophied  Tonsils  by  Caus- 
tic Applications. — Among  the  various  caustics  for  local 
use  in  causing  shrinkage  of  tonsillar  hypertrophies,  Dr. 
Chisholm  {Virginia  Medical  Monthly)  has  found  the 
chloride  of  zinc  the  most  available  and  the  least  annoy- 
ing to  the  patient.  He  employs  it  in  the  following  man- 
ner :  A  wire,  the  size  of  a  fine  knitting-needle,  is  rough- 
ened for  a  half  inch  from  one  end,  so  that  it  may  hold  a 
fibre  of  absorbent  cotton  twisted  upon  it.  Dip  this  into 
a  saturated  solution  ;of  chloride  of  zinc,  and  thrust  it  to 
the  very  bottom  of  the  crypt,  and  keep  it  there  several 
seconds.  When  withdrawn  the  whitened  orifice  marks  the 
cauterization.  By  renewing  the  cotton  for  each  follicle, 
several  may  be  thoroughly  cauterized  at  the  same  sitting, 
without  causing  any  annoying  irritation  to  the  throat 
A  very  few  applications  will  cause  the  gland  to  shrink, 
as  will  be  seen  one  week  after  the  destructive  cauteriza- 
tion has  been  made  to  the  interior  of  the  follicles. 


November  29,  1884.] 


THE   MEDICAL  RECORD. 


599 


Explosive  Drugs. — Several  instances  are  related  in 
the  Deutsche  Medicinal-Zeitung  of  September  29,  1884, 
oi  injuries  resulting  from  the  explosion  of  compounds 
ordered  in  physicians'  prescriptions.  A  gargle  was  or- 
dered of  chlorate  of  potassium,  chloride  of  iron,  and  gly- 
cerine. It  was  prepared,  and  five  minutes  later  the  bottle 
exploded  in  the  purchaser's  pocket,  wounding  him  quite 
severely  with  the  fragnjents  of  glass.  A  mixture  of  hy- 
pophosphite  of  lime,  chlorate  of  potassium,  and  lactate 
of  iron  exploded  and  nearly  killed  the  prescription  clerk 
who  was  componnding  it.  Even  the  simple  trituration 
of  calcium  hypophosphite  is  dangerous  ;  a  young  phar- 
maceutist was  killed  by  an  explosion  which  was  caused 
by  the  shaking  of  a  solution  of  this  substance.  Physi- 
cians not  infrequently  order  a  solution  of  chromic  acid 
in  glycerine.  But  when  the  acid  is  added  quickly  and 
all  at  once  to  the  glycerine  a  readily  explosive  substance 
like  nitro-glycerin^  is  formed.  Chlorate  of  potassium 
when  mixed  with  tannin  or  muriate  of  morphia  often  ex- 
plodes. The  combination  of  iodide  and  preparations  of 
ammonia  must  be  made  cautiously,  as  iodide  of  nitrogen 
is  formed,  which  explodes  on  the  slightest  touch.  In- 
deed one  ought  to  be  very  careful  in  ordering  and  com- 
pounding mixtures  in  which  easily  reducible  substances 
enter — such  as  the  chlorates,  the  hypophosphites,  the 
nitrates,  preparations  of  iodine  or  ammonia,  chromic 
acid,  glycerine,  permanganate  of  potash,  etc  If  physi- 
cians would  but  remember  the  danger  of  explosions  in 
preparing  such  compounds,  they  would  less  often  put 
the  lives  of  druggists  and  of  their  own  patients  in 
jeopardy. 

Th*  Antipyretic  Action  of  the  Alkaloids  of 
Quebracho. — ^At  the  recent  meeting  of  the  French  As- 
sociation for  the  Advancement  of  Science  at  Blois,  a 
paper  was 'presented  by  Drs.  Huchard  and  Eloy  on  this 
subject  (Le  Frogris  M^dicaly  October  4,  1884).  There 
are  many  alkaloids  of  this  drug,  no  less  than  six  having 
been  already  isolated.  Numerous  experiments  upon  rab- 
bits having  demonstrated  the  antipyretic  action  of  these 
alkaloids,  the  authors  were  led  to  make  trial  of  them  in 
the  human  subject  In  a  certain  number  of  patients 
with  typhoid  fever,  to  whom  quinine  had  been  given  with- 
out effect,  a  notable  reduction  of  temperature  was  ob- 
tained by  the  hypodermic  injection  of  the  muriate  of 
aspidospermine  in  doses  of  one  and  a  half  to  three 
grains.  This  latter  amount  should  never  be»  exceeded. 
The  authors  noted  especially  the  rapid  reduction  of  tem- 
perature following  the  exhibition  of  these  several  alka- 
loids, and  also  remarked  upon  the  changes  occurring  in 
the  blood  after  their  administration.  The  blood  is 
changed  in  color  in  a  way  very  similar  to  what  occurs 
after  poisoning  by  carbonic  oxide. 

Paralysis  Caused  by  the  Use  of  Crutches. — Dr. 
Vinay  reports  the  case  of  a  man,  sixty-three  years  of  age, 
who  suffered  from  paralysis  of  the  extensors  of  the  fore- 
arms and  of  the  long  supinators  following  upon  the  use 
of  crutches.  The  crutches  were  of  very  rude  construc- 
tion and  had  no  supports  for  the  hands.  All  the  affected 
muscles,  with  the  exception  of  the  right  triceps,  reacted 
to  the  faradic  current.  A  treatment  by  means  of  sulphur 
baths  and  electricity  was  instituted,  and  at  the  end  of  a 
month  all  the  muscles  were  restored  to  their  normal 
function,  except  the  right  triceps.  The  use  of  the  poorly 
made  crutches  was,  of  course,  abandoned.  The  author 
believes  that  paralysis  of  the  triceps  from  this  cause  is 
of  much  more  frequent  occurrence  than  is  generally  sup- 
posed. He  advises  a  treatment  of  this  condition  by  the 
faradic  current,  friction,  and  sulphur  baths,  and  removal 
of  the  exciting  cause. — Deutsche  Medicinal- Zeitung^  No. 
77,  1884. 

Syphilitic  Arteritis. — At  the  meeting  at  Blois  of  the 
French  Association  for  the  Advancement  of  Science,  Dr. 
Leudet  related  a  case  of  syphilitic  arteritis,  accompanied 
by  cerebral  symptoms,  occurring  four  years  after  the  ap- 
pearance   of  the  initial  sore.     The  superficial  temporal 


arteries  of  both  sides  became  cord-like,  and  the  pulsa- 
tions ceased  in  them.  The  cerebral  symptoms,  pain  and 
loss  of  memory,  occurring  at  the  same  time  indicated  a 
concomitant  lesion  of  the  brain.  Under  the  influence  of 
iodide  of  potassium  all  these  troubles  subsided,  the  ar- 
teries lost  their  indurated  feel,  the  pulsations  returned, 
and  the  cerebral  symptoms  gradually  passed  away.  The 
author  thought  this  case  was  important  as  showing  the 
curability  both  of  syphilitic  arteritis  and  of  cerebfal  sy- 
philis.— Lyon  Medical,  October  5,  1884. 

Biliary  Calculus  Passed  by  the  Rectum. — Drs. 
Secr^tan  and  Larginer  relate  the  case  of  a  man  who  suf- 
fered from  frequent  attacks  of  hepatic  colic.  These  at- 
tacks ceased  for  the  time  after  the  expulsion  of  a  lumbri- 
coid  worm  by  the  mouth.  But  they  soon  recurred,  and 
were  accompanied  by  violent  nervous  crises,  acute  mania, 
left  hemiplegia,  and  loss  of  the  intellectual  faculties,  espe- 
cially of  the  memory.  Three  months  later  these  nervous 
symptoms  suddenly  ceased  upon  the  expulsion  by  the 
anus  of  a  large  biliary  calculus,  nearly  three  inches  in 
length  by  an  inch  and  a  half  in  thickness.  The  patient 
had  never  presented  any  symptoms  of  intestinal  obstruc- 
tion, and  the  reporters  believed  that  a  fistula  had  been 
established  between  the  gall-bladder  and  the  colon. — 
Revue  de  Chirurgie^  October  10,  1884. 

The  Mechanism  of  Rotation  of  the  Forearm. — 
Heiberg  is  of  the  opinion  that  in  rotation  of  the  hand  the 
radius  does  not  simply  turn  around  the  ulna,  but  that 
both  radius  and  ulna  rotate  around  an  axis  lying  between 
the  two.  Dr.  v.  Meyer  agrees  with  Heiberg  that  this 
may  occur  in  certain  cases,  but  regards  it  as  occurring 
only  exceptionally,  and  in  cases  in  which  the  ligaments 
of  the  elbow  are  stretched  to  a  very  considerable  extent. 
He  concludes,  therefore,  that  this  rotatory  movement  of 
the  ulna  is  not  normal  but  is  due  to  a  partial  subluxation. 
—Ceniralblati  fur  Chirurgie,  No.  38,  1884. 

A  Prepuce  Dilator  for  the  Treatment  of  Phim- 
osis WITHOUT  Operation. — Dr.  Richmond  writes  in  the 
Medical  Pressy  October  i,  1884,  concerning  a  new  instru- 
ment which  he  has  devised  for  the  treatment  of  phimosis 
by  gradual  stretching.  He  says  that  the  only  method  of 
treating  phimosis,  in  common  practice,  is  by  operation. 
There  are,  however,  a  great  many  patients  suffering  from 
this  malady  who  absolutely  refuse  to  undergo  any  opera- 
tion for  its  relief.  Numbers  of  cases  are  constantly 
presenting  themselves  of  men  considerably  advanced  in 
years  who  have  never  been  able  to  get  their  foreskins 
backy  and  have  consequendy  suffered  continually  from 
discharges  attributable  solely  to  the  irritation  attendant 
on  this  condition.  Yet  many  such  patients  will  rather 
pass  their  lives  with  the  inconvenience  and  risk  which 
this  state  of  things  involves  than  submit  to  the  knife. 
There  can,  however,  be  only  one  other  possible  means 
of  treating  phimosis,  and  that  is  by  stretching  the  prepuce. 
But  this  method  appears  to  be  very  seldom  put  into  prac- 
tice, for  when  it  is  tried  it  generally  results  in  failure.  I 
can  see  no  reason,  however,  why  the  skin  and  mucous 
membrane  surrounding  the  glans  penis  should  not  be  as 
freely  dilatable  as  in  other  parts  of  the  body.  The  reason 
of  the  failure,  I  take  it,  is  simply  that  no  proper  instru- 
ment has  been  invented  for  the  purpose.  Extemporized 
instruments,  such  as  dressing  forceps,  aneurism  needles, 
or  blunted  hooks,  are  painful  and  inadequate  dilators. 
An  instrument  proper  for  the  purpose  should  possess 
blades  which  could  be  introduced  separately;  th^ blades 
must  be  of  suitable  size  and  shape  to  suit  the  case ;  and 
it  should  be  possible  to  open  them  parallel  to  one  an- 
other or  at  any  angle.  The  instrument  which  I  have 
devised  for  the  purpose  consists  of  two  rods,  connected 
together  by  means  of  two  long  screws.  At  one  extiemity 
they  are  bent  inward,  and  fixed  to  two  blades.  These 
blades  can  be  removed,  and  may  be  of  any  size  and 
shape.  The  rod  is  of  tuning-fork  shape,  with  a  screw- 
nut  sliding  in  the  groove  between  the  two  branches  of  the 
fork.     Through  the  nut  is  passed  a  long  screw,  the  end 


6oo 


THE   MEDICAL   RECORD. 


[November  29,  1884 


of  which  is  received  into  a  cup  working  on  a  hinge-joint 
attached  to  a  cylinder,  which  slides  along  the  bar.  The 
screw-end  may  be  detached  from  the  socket  by  depress- 
ing a  little  spring.  The  blades  are  passed  separately 
down  between  the  foreskin  and  glans.  Very  small  blades 
are  used  at  first,  and  they  are,  of  course,  previously  oiled 
to  facilitate  their  passage.  They  are  then  attached  to  the 
rods,  which  are  united  by  fixing  the  end  of  the  screw 
into  the  cup-joint.  Gradual  extension  can  then  be  ap- 
plied by  turning  the  nuts.  Since  there  is  a  joint  at  the 
cylinder,  the  blades  may  be  opened  parallel  to  one  an- 
other or  at  any  angle,  and,  in  fact,  the  relative  position 
of  the  blades  may  be  altered  in  an^  direction.  The  idea 
is  not  to  stretch  the  foreskin  forcibly  and  at  one  sitting, 
but  to  dilate  it  gradually  in  the  same  manner  as  a  strict- 
ure of  the  urethra  is  dilated,  by  repeatedly  passing  a 
catheter.  If  the  instrument  be  used  once  or  twice  a 
week  for  about  ten  minutes  at  a  time,  the  foreskin  will 
in  most  cases  go  back  in  a  month  or  six  weeks.  The 
larger  blades  are  used  to  thoroughly  stretch  the  tissues 
and  complete  the  treatment.  The  foreskin  may  thus  be 
dilated  to  any  reasonable  extent,  and  will,  after  a  time, 
easily  roll  back  over  the  corona.  The  instruments  are 
made  by  Messrs.  Arnold  &  Sons,  of  Smithfield,  England. 

An  Autodidactic  View  of  Diabetes. — In  the  Ga- 
zette des  Hdpitauxy  a  physician  has  published  a  confrere's 
autobiography  in  so  far  as  it  relates  to  the  careful  ob- 
servations of  his  own  case,  which  was  one  of  pronounced 
diabetes  mellitus.  The  physician  in  question,  having 
kept  an  eye  on  himself  for  many  years,  finally  decided 
that  |;lycosuria  was  a  symptom  of  active  and  chronic 
hepatic  congestion  dependent  upon  gout  Like  the  latter, 
it  should  be  treated  by  regulating  the  diet  and  not  by  the 
exhibition  of  useless  drugs.  He  believes  in  white  meat, 
^ggs  )fish,  chicory,  spinach,  artichokes,  and  lettuce.  Ab- 
solute abstention  from  fruits,  sweets,  farinaceous  foods, 
as  well  as  coffee  and  all  alcoholic  beverages,  is  insisted 
upon. 

I^HPeritonitis  Resulting  from  Diseases  of  the  Ver- 
miform Appendix. — Professor  With,  dealing  with  this 
subject  before  the  International  Medical  Congress,  said 
that  the  inflammation  of  the  right  iliac  fossa,  known  by 
the  name  of  perityphlitis,  very  often  began  in  ulceration 
and  perforation  of  the  vermiform  appendix.  Peritonitis 
of  this  origin  was  called  appendicular  peritonitis,  and  was 
met  with  under  three  forms  or  conditions,  generally  well 
marked ;  as  adhesive  appendicular  peritonitis  (before 
perforation),  and  appendicular  peritonitis,  local  or  gen- 
eral (after  perforation).  As  regarded  treatment,  the  chief 
indication  was  to  give  the  intestinal  canal  as  complete 
rest  as  possible.  To  this  end,  sufficiently  large  doses  of 
opium  and  morphia  should  be  used,  as  well  as  complete 
abstention  from  laxatives  and  enematas,  kept  up  for  a 
period  of  twenty-four  hours,  if  that  were  thought  neces- 
sary. By  means  of  this  treatment,  the  indication  for  sur- 
gical interference  underwent  a  considerable  restriction. 

AsEPTOL. — A  phenol  compound,  termed  orthoxyphe- 
nylsulphurous  acid,  has  been  recently  introduced  into 
therapeutics  under  the  name  of  **  aseptol,"  this  title  hav- 
ing been  given  to  it  on  account  of  its  remarkable  germi- 
cide qualities,  which  excel  those  of  carbolic  and  salicylic 
acids.  Aseptol  is  an  amber-colored  fluid,  of  a  density 
of  1,400  ;  it  has  a  slight  odor,  but  is  more  pleasant  to 
the  smell  and  is  less  poisonous  than  carbolic  acid.  Last 
Novemoer,  Drs.  I^eroy  and  Van  den  Shrieck,  of  Ant 
werp,  studied  the  therapeutic  applications  of  aseptol,  and 
reported  most  satisfactory  results  as  an  antiseptic.  It 
has  the  following  advantages  over  antiseptics  in  common 
use  :  I.  It  is  very  soluble  in  water.  2.  It  is  very  slightly 
caustic.  3.  It  is  free  from  irritative  qualities,  and  may 
be  applied  for  a  long  time  to  the  skin,  the  eyes,  the  blad- 
der, etc.  4.  Finally,  its  slight  toxicity,  which  permits  its 
use  internally  in  considerable  doses,  and  also  the  appli- 
cation of  concentrated  solutions  in  diphtheritic  i^haryn- 
gitis  and  laryngitis. — La  France  Midicale. 


^jedical  Stjems. 


'Contagious  Diseases— Weekly  Statement.— R^ 
port  of  cases  and  deaths  from  contagious  diseases  r^ 
ported  to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  November  22,  1884  : 


Week  Ending 


Cat€s. 

November  15, 1884 
November  22,  188^ 

Deaths. 

November  15,  1884 
November  22,  1884 


h 


1^ 


I 


107 

"5 


Bell's  Law  Discovered  by  Magendie. — Professor 
Chapman  says  the  credit  of  demonstrating  the  functions 
of  the  anterior  and  posterior  roots  of  the  spinal  nerves 
belongs  to  Magendie,  and  not  to  Sir  Charles  BclL 
When  Magendie,  in  182 1,  published  the  correct  idea, 
Bell  collected  and  destroyed,  as  he  thought,  the  whole 
edition  of  his  own  pamphlet,  printed  in  181 1,  which  ad- 
vanced the  idea  that  the  posterior  roots  are  trophic  only, 
and  quickly  published  another  containing  the  true  idea. 
Professor  Chapman  has  seen  a  copy  of  Bell's  treatise  oC 
181 1  which  escaped  destruction,  and  is  now  owned  by 
the  celebrated  Richard  Owen. 

GoNORRHCEA  AND  Chordee. — Troublcsome  gonor- 
hoeal  cases  do  not  fail  to  occur  except  in  the  experience 
of  those  who  are  in  the  possession  of  unfailing  remedies. 
A  retired  army  surgeon,  without  apparently  expecting 
such  good  results,  ordered  for  an  officer,  some  fifteen 
years  ago,  who  was  just  about  to  present  himself  for  duty, 
but  who  was  suffering  from  gonorrhoea  associated  with 
an  intense  chordee  at  night,  the  following  two  prepara. 
tions:  aquae,  3  vij.,  mucilago  acaciae,  5J.i  ext  belladon- 
nae,  gr.  xx.,  and  zinci  sulph.,  gr.  xx.  A  teaspoonful  in- 
jected frequently.  The  other  is  an  external  application 
consisting  of  unguenti  spermaceti  3  iv.,  unguenti  hydrarg., 
3  iv.,  ext*  belladonnae,  gr.  x.,ext.  opii,  gr.  x.,  to  be  smeared 
freely  along  the  perineum  and  around  the  crura  penis  at 
night.  "  Complete  cure  "  occurred  within  a  week.  The 
following  injection  for  gonorrhoea  is  also  recommended 
It  is  claimed  to  be  superior  to  any  other  single  injection: 
g.  Pulv.  iodoform,  20;  acidi  carbolici,  10;  glycerini,  80; 
aquae  destillatae,  200. 

Heart  Beats. — Dr.  N.  B.  Richardson,  of  London, 
says  he  was  recently  able  to  convey  a  considerable 
amount  of  conviction  to  an  intelligent  scholar  by  a 
simple  experiment.  The  scholar  was  singing  the  praises 
of  the  "ruddy  bumper,"  and  saying  he  could  not  get 
through  the  day  without  it,  when  Dr.  Richardson  said 
to  him :  "  *  Will  you  be  good  enough  to  feel  my  pulse 
as  I  stand  here?'  He  did  so.  I  said,  *  Count  it  care- 
fully; what  does  it  say?'  *Your  pulse  says  74.'  I  then 
sat  down  in  a  chair,  and  asked  him  to  count  it  again. 
He  did  so,  and  said,  *  Your  pulse  has  gone  down  to  70-' 
I  then  lay  down  on  the  lounge,  and  said :  *  Will  you  take 
it  again?'  He  replied:  'Why,  it  is  only  64;  what  an 
extraordinary  thing!'  1  then  said:  *When  you  lie 
down  at  night,  that  is  the  way  nature  gives  your  heart 
rest.  You  know  nothing  about  it,  but  that  beating  orgar 
is  resting  to  that  extent ;  and  if  you  reckon  it  up  it  is  a 
great  deal  of  rest,  because  in  lying  down  the  heart  is 
doing  ten  strokes  less  a  minute.  Multiply  that  by  sixty, 
and  it  is  six  hundred ;  multiply  it  by  eight  hours,  and 
within  a  fraction  it  is  five  thousand  strokes  different;  and 
as  the  heart  is  throwing  six  ounces  of  blood  at  every 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


601 


stroke,  it  makes  a  difference  of  thirty  thousand  ounces  of 
lifting  during  the  night  When  I  lie  down  at  night  with- 
out  any  alcohol,*  that  is  the  rest  my  heart  gets.  But 
when  you  take  your  wine  or  grog  you  do  not  allow  that 
rest,  for  the  influence  of  alcohol  is  to  increase  the  num- 
ber of  strokes,  and  instead  ol  getting  this  rest,  you  put 
on  something  like  fifteen  thousand  extra  strokes,  and  the 
result  is  you  rise  up  very  seedy  and  unfit  for  the  next 
da/s  work  till  you  have  taken  a  little  more  of  the  "ruddy 
bumper,"  which  you  say  is  the  soul  of  man  below.'  " — 
Gaillards  fournai. 

The  Treatment  of  Stammering. — A  correspondent 
in  the  London  Lancet  of  September  37th  writes  that 
anyone  may  be  cured  of  stammering  by  simply  mak- 
ing an  audible  note  in  expiration  before  each  word. 
Stammerers  can  sing  as  easily  as  other  persons.  Jacky 
Broster,  of  Chester,  who  made  a  large  fortune  by  curing 
stammering,  simply  made  his  pupils  say  her  before  each 
word  beginning  with  a  consonant. 

The  Pecuniary  Value  of  Enterotomy. — Dr.  Sutton, 
of  Pittsburg,  having  performed  enterotomy  on  the  wife  of 
a  wealthy  resident  of  that  city,  removing  four  inches  of 
intestine,  was  encouraged,  by  the  fact  of  her  complete 
recovery,  to  send  in  a  bill  of  $1,000  for  the  operation 
and  twenty-two  days  of  attendance  in  the  after-treatment. 
Each  member  of  the  jury,  who  finally  adjudicated  the 
matter,  wrote  on  a  slip  what  he  thought  would  be  a  proper 
fee,  and  the  sum  total  of  the  amounts  thus  voted,  divided 
by  twelve,  was  agreed  upon  as  the  verdict.  The  dividend 
was  $330.  One  of  the  jurors  thought  about  $10  would  be 
a  fair  price,  and  another  was  willing  to  allow  $30. — Age. 

Lata  or  Miryachit. — In  Java,  according  to  the  Brit- 
ish Medical  Journal^  miryachit  is  known  by  the  name  of 
lata.  The  person  affected  with  it  is  compelled  to  imitate 
everything  he  sees  or  hears.  Our  contemporary  mentions 
an  amusing  case  in  which  an  Irish  butler  who  was  famil- 
iar with  the  symptoms  of  the  disease  took  advantage  of 
his  knowledge  to  secure  a  glass  of  much-coveted  wine  : 
A  doctor  dined  with  a  friend,  with  whom  he  discussed  the 
peculiarities  of  the  disease.  The  host  pushed  forward  a 
bottle  with  the  request  to  "try  that,  doctor;  it's  ten 
years  old."  The  doctor  took  a  stiff  glass,  and,  smacking 
his  lips,  pronounced  it  "  tip-top."  Suddenly  Barney,  who 
had  been  present  during  the  conversation,  seized  a  glass 
and,  filling  it  to  the  brim,  drank  it  off,  smacked  his  lips 
and  pronounced  it  "tip-top."  "Confound  you/'  shouted 
the  infuriated  host,  "what  do  you  mean,  sir?"'  "Shure, 
sir,"  demurely  replied  Barney,  "  oi'm  afeard  oi'm  afflicted 
wid  the  latha." 

Regulatory  Albuminuria. — Rosenbach  defines  regu- 
latory albuminuria  as  an  albuminuria  in  which  the  quan- 
tity and  quality  of  the  urine  are  normal  (except  in  con- 
taining albumen),  and  in  which  there  are  present  no 
products  of  inflammation,  such  as  tube-casts  or  blood- 
corpuscles.  In  such  cases  the  kidneys  are  for  the  time 
functionating  more  than  they  normally  do,  and  the 
albuminuria  arises  from  anomalies  of  the  blood  or  of 
tissue-change,  and  not  from  any  disease  of  the  kidneys 
themselves.  It  is  to  be  remembered  that  in  these  cases 
the  blood  may  be  either  absolutely  or  relatively  richer  in 
albumen  than  is  normally  the  case.  In  the  first  of  these 
cases  the  blood  holds  absolutely  more  albumen  in  solu- 
tion than  normal,  and  this  may  be  due  to  a  great  absorp- 
tion of  albuminates  from  the  food,  to  the  transfusion  of 
blood,  or  to  peptonuria  and  the  absorption  of  large  pus 
collections.  In  the  second  case,  the  blood  contains  re- 
latively more  albumen  than  normal — relatively,  that  is, 
to  its  power  of  combining  albumen — and  this  arises  from 
increased  loss  of  water  through  the  skin  or  intestine,  from 
diminished  supply  of  water  to  the  system,  or  from  dimin- 
ished functionating  power  in  the  white  blood-corpuscles. 
In  both  these  cases  the  excretory  organs  strive  to  reduce 
the  albuminous  concentration  of  the  blood  to  the  normal 
level,  and  hence  the  regulatory  albuminuria.  Rosenbach 
holds  that  the  only  characteristics  of  nephritis  in  its 


strictest  sense  are  white  (and  the  so-called  "fatty") 
blood-corpuscles,  and  the  tube-casts  which  are  formed 
out  of  these  corpuscles.  He  holds  the  hyaline  corpuscles 
only  as  an  indication  of  the  presence  of  albumen,  since, 
as  is  well  known,  they  often  occur  when  there  can  be  no 
question  of  renal  lesion.  The  red  blood-corpuscles  are 
only  indications  that  the  process  possesses  considerable 
acuteness. — Zeitschrift  fiir  Klinische  Medizin. 

The  Milk  of  Pregnant  Cows  Unfit  for  Infants. 
— Dr.  Ernest  Mammen,  of  Bloomington,  III.,  expresses 
an  opinion  below  which  is  important  if  true,  but  which 
will  be  received  with  some  incredulity.  He  says: 
"  I  have  read  with  much  interest  the  articles  by  Drs. 
Binnie  and  Vidal  in  recent  issues  of  The  Record  (Sept- 
ember 13th  and  October  25th),  and  I  heartily  agree  with 
these  writers  in  their  advocacy  of  cow's  milk,  fresh  and 
pure,  as  the  best  substitute  for  mother's  milk.  But  there 
is  one  factor  which,  in  my  experience,  is  often  productive 
of  harm  that  neither  of  them  has  mentioned.  The  milk  of 
the  pregnant  cow  is  unfit  for  consumption  by  the  human 
infant.  This  fact  is  too  often  overlooked,  when  by  care- 
ful investigation  the  disturbance  of  stomach  and  bowels 
in  cases  of  infantile  diarrhoea  could  be  traced  to  the  use 
of  milk.  Where  mixed  milk  is  used  the  danger  is  that  a 
proportion  of  it  comes  from  pregnant  cows.  All 
hygienic  care  of  the  animals  cannot  make  up  for  this 
condition  of  the  milk,  neither  can  the  addition  of  sod. 
bicarb.,  common  salt,  lime-water,  etc.,  destroy  the 
deleterious  principle,  therefore  my  rule  is  to  avoid  it. 
I  have  recently  had  under  personal  observation  a  child 
weaned  at  six  weeks,  and  put  upon  cow's  milk.  A 
good  healthy  animal  was  selected,  and  her  milk,  with 
the  proper  dilution  and  additions,  agreed  perfectly 
for  three  months,  and  that,  too,  during  the  summer. 
At  the  end  of  this  time  the  cow  was  found  with  calf, 
and  the  infant's  digestion  was  immediately  disturbed.  An 
obstinate  diarrhoea  set  in,  which  could  not  be  controlled 
until  another  cow,  not  pregnant,  was  substituted,  when 
the  child  recovered  and  digestion  was  restored.  I  could 
cite  other  similiar  instances,  but  the  above  illustrates  the 
importance  of  this  matter." 

Ozone  in  the  Treatment  of  Rheumatism. — Dr.  E. 
Br6mond  Fils  has  devised  an  apparatus  for  the  application 
of  vapor-baths  of  turpentine  in  cases  of  rheumatism, 
vesical  troubles,  lithiasis,  etc.  Ozone  is  evolved  in  the 
process,  and  is  believed  to  be  the  active  curative  agent. 

The  Chloroform  Treatment  of  Tapeworm. — We 
have  received  several  communications  upon  the  above 
subject  Dr.  John  H.  Thompson,  of  this  city  writes  : 
"  Chloroform  is  not  a  dangerous  remedy  for  tapeworm  if 
properly  used,  but  where  any  one  gives  a  dose  six  times 
as  large  as  necessary  of  a  deadly  drug  then  it  may  be- 
come dangerous.  I  have  thirteen  feet  of  taenia  solium, 
with  the  head,  that  came  from  a  patient  March  27,  1870, 
after  having  suffered  with  it  for  fifteen  years,  and  been  to 
London  and  Paris  to  be  treated  for  it.  I,  too,  had  tried 
pumpkin  seeds,  filix  mas,  and  some  other  remedies,  but 
succeeded  with:  5-  Chloroformi,  3j. ;  simple  syrup, 
I  j.  M.  One-third  given  at  7,  9,  and  1 1  o'clock,  fol- 
lowed at  12  o'clock  by  ol.  ricini,  3J.,  and  the  worm 
came  at  1.30  p.m.  from  the  happiest  man  I  almost  ever 
saw.  I  had  caused  my  patient  to  fast  absolutely  for  the 
twenty-four  hours  previous  to  taking  my  prescription,  ex- 
cept allowing  him  to  chew  slipper}-  elm  bark.  I  have 
used  the  remedy  in  the  same  manner  since  with  success." 
Dr.  F.  H.  Enders,  of  Wailuku,  Sandwich  Islands,  writes : 
"  I  have  treated  five  cases  of  tapeworm  at  the  Malulani 
Hospital  successfully  with  the  following :  ]$ .  Chloroform, 
fi.  ext.,  filix  mas,  &a  3  j. ;  emuls.  ol.  ricini,  |  iij.  M. 
To  be  taken  in  the  early  morning.  No  food  allowed 
until  thorough  action  of  the  bowels.  The  entire  worm 
was  brought  away  in  each  case,  with  no  unpleasant  re- 
sults." Dr.  Charles  H.  French,  of  Waterbury,  Conn., 
writes  that  he  succeeded  with  the  following :  5 .  Olei 
tiglii,  gtt.  j.;  chloroform,  3j.;  syr.  glycyrrhiza,  §j.     M, 


602 


THE   MEDICAL  RECORD. 


[November  29,  1884* 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor- 


Published  BY 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Lafayette  Place. 

New  York,  November  29,  1884. 

KOCH'S    DEFENCE    OF    THE    CHOLERA 
BACILLUS. 

Soon  after  the  announcement  by  Koch  of  his  discovery 
of  the  specific  microbe  of  Asiatic  cholera,  the  now  well- 
known  comma-bacillus,  there  appeared  in  the  medical 
press  various  doubts  concerning  the  diagnostic  importance 
of  this  newly  fledged  organism.  We  have  kept  our  readers 
amply  informed  in  regard  to  the  various  criticisms  of- 
fered, as  well  as  the  protests  made,  against  the  accept- 
ance of  Koch's  conclusions. 

In  the  Deutsche  Medizinische  Wochenschrifi  of  No- 
vember 6,  1884,  the  distinguished  German  bacteriologist 
has  just  published  a  comprehensive  reply  to  his  critics. 
The  most  profound  scepticism  can  hardly  hold  out  longer 
against  the  new  evidence  adduced  by  Koch  in  support  of 
his  former  claims,  touching  the  relation  of  the  comma- 
bacillus  to  Asiatic  cholera. 

Dr.  E.  C.  Wendt,  of  this  city,  in  an  article  published 
on  page  589  of  the  present  number  of  The  Medical 
Record,  alludes  to  these  later  investigations,  and 
infers  therefrom  the  necessity  of  scientific  bacterio- 
scopy.  Without  wishing  to  subscribe  to  all  his  sugges- 
tions, we  must  nevertheless  admit  that  the  profession 
of  our  country  is  not  as  familiar  with  modem  bac- 
teriological methods  as  could  be  wished.  It  may  yet 
be  shown  that  the  practical  utility  of  finding  certain  mi- 
crobes in  suspected  cases  has  been  overrated.  But 
to  deny  them  all  diagnostic  importance  is  to  assume 
a  voluntary  blindness.  From  the  accumulated  evi- 
dences now  before  us,  it  would  seem  that  the  burden 
of  proof  rests  with  those  who  deny  or  dispute  the  valid- 
ity of  Koch's  statements. 

With  especial  reference  to  cholera,  Koch  shows,  in  the 
article  referred  to,  that  the  comma-bacilli  can  be  recog- 
nized as  such  only  through  the  totality  of  their  proper- 
ties. Any  single  attribute,  such  as  their  peculiar  shape, 
or  a  certain  behavior  toward  stains,  is  not  sufficiently  char- 
acteristic to  differentiate  them  from  other  and  possibly 
quite  harmless  bacteria. 

The  alleged  comma-bacillus  ordinarily  found  in  the 
mouth,  and  claimed  by  Lewis  to  be  identical  with  the 
cholera  microbe,  has  long  ago  been  examined  by  Koch 
with  negative  results  as  to  any  discoverable  relation  be- 
tween the  two.  Again,  as  regards  the  well-known  allega- 
tions of  Prior  and  Finkler,  Koch  shows  that  they  em- 
ployed faulty  methods  and,  therefore,  secured  results 
devoid  of  significance.    The  specimens  of  their  comma- 


bacillus  which  they  submitted  to  him  were  found  by 
Koch  to  contain  four  separate  kinds  of  bacteria,  but  no 
cholera  bacilli.  For  a  detailed  account  of  the  essential  dif- 
ferences  between  the  true  comma-bacillus  and  Prior's 
pseudo-bacillus  we  must  refer  to  Koch's  original  paper. 
It  is  further  stated  by  the  indefatigable  German  scientist 
that  in  three  cases  of  undoubted  cholera  morbus  he 
found  an  abundance  of  various  bacteria,  but  in  no  single 
instance  any  comma-bacilli.  Moreover,  Koch  and  his 
stafif  of  collaborators  have  already  examined  the  alvine 
evacuations  in  hundreds  of  cases  of  diarrhoea,  dysentery, 
and  other  affections,  as  well  as  in  health.  Comma-bsk 
cilli  were  never  found. 

In  a  rapidly  fatal  case  of  arsenical  poisoning,  when  the 
intestines  and  their  contents  showed  naked-eye  appear- 
ances closely  resembling  those  of  true  cholera,  no  com- 
ma-bacilli  could  be  detected. 

And,  finally,  to  crown  all,  cholera  or  fatal  choleraic 
symptoms  have  been  experimentally  induced  in  various 
animals  by  the  introduction  of  pure  cultures  into  their 
intestines.  Almost  invariably  the  dead  animals  showed 
an  abundance  of  the  characteristic  comma-bacilli  in  the 
intestinal  tract.  Koch  reiterates,  therefore,  with  added 
emphasis,  his  former  assertions  that  the  comma-bacillus 
is  the  specific  microbe  of  Asiatic  cholera,  and  occurs 
neither  in  health  nor  in  any  other  disease.  The  sole 
point  now  on  which  the  doubter  can  stand  is  that  of  deny- 
ing the  specific  character  of  the  inoculated  disease.  There 
does  not  seem,  however,  sufficient  strength  in  this  posi- 
tion to  excuse  either  individuals,  health  boards,  or  govern- 
ments from  refusing  to  act  upon  the  theory  that  Koch  is 
right.  And  in  this  connection  Dr.  Wendt's  suggestion, 
that  we  familiarize  ourselves  with  scientific  bacterioscopy, 
seems  eminently  proper,  and  should  be  strongly  urged 
upon  our  authorities. 

Koch's  discovery  is  one  of  the  grandest  steps  which 
have  been  taken  in  this  century  toward  giving  certainty  to 
clinical  medicine.  And  one  must  think  almost  with  dis- 
may of  the  tremendous  collapse  of  scientific  hypotheses 
and  dogmatic  teaching  which  its  confirmation  must  pro- 
duce. If  it  can  be  shown  (and  this  yet  remains  to  be 
done)  that  the  bacillus  is  alone  a  sufficient  cause  of  chol- 
era, that  it  needs  no  prepared  ground  or  special  epidemic 
influence,  the  revolution  of  views  necessitated  will  be 
indeed  most  extraordinary.  But  even  should  more  ex- 
tended observation  show  that  the  commas-bacillus  can 
produce  cholera  only  under  peculiarly  favorable  condi- 
tions, its  diagnostic  significance  would  yet  remain.  And 
the  early  discovery  of  the  microbe  having  all  the  weight 
of  a  pathognomonic  symptom,  would  still  give  us  a  better 
chance  of  promptly  suppressing^  an  incipient  epidemic 
than  was  ever  before  afforded  us. 


THE  PRESENT  STATUS  OF  THE  QUESTION  CONCERN- 
ING  THE  TREATMENT  OF  GOITRE. 

Although  goitre  is  by  no  means  a  frequent  malady  in 
our  country,  there  is,  nevertheless,  among  the  foreign- 
bom  population  enough  of  it  to  keep  alive  a  certain  in- 
terest in  the  disease,  and  especially  as  regards  the  means 
at  our  coDomand  for  overcoming  the  annoyance  of  great 
disfigurement,  if  not  the  turning  aside  of  grave  danger- 
Hence  neither  physician  nor  surgeon  can  well  afford  to 


November  29,  1884*] 


THE   MEDICAL  RECORD. 


603 


ignore  any  positive  advances  in  the  therapy  of  this  per- 
plexing affection.  In  No.  244  of  the  Sammlung  Klin- 
ischer  Varirdge^  October  8,  1884,  Dr.  P.  Bruns,  of  Tubin- 
gen, publishes  an  instructive  review  of  the  subject  in  its 
most  recent  aspect,  but  more  particularly  from  the  point 
of  view  of  the  surgeon. 

The  author  explains  that  it  is  a  serious  error,  still 
prevalent  in  some  quarters,  to  suppose  that  the  steady 
growth  and  enlargement  of  a  goitre  constitute  its  chief 
dangers.  A  large  experience  has  shown  him  that  fre- 
quently the  most  formidable  in  volume  are,  at  the  same 
time,  the  most  harmless  tumors.  It  is  the  small-sized 
struma,  and  more  particularly  the  substernal  variety, 
that  is  potent  for  mischief,  and  often  leads  to  a  fatal  issue. 
Death,  indeed,  happens  unexpectedly  in  some  cases 
where  no  violent  symptoms  of  any  kind  had  warned 
patient  and  physician  of  impending  danger.  The 
lightning-like  rapidity  of  such  an  accident  is  explained 
by  asphyxia  and  cardiac  paralysis,  following  a  sudden 
bending  and  collapse  of  the  wind-pipe.  Tracheotomy  per- 
formed at  the  earliest  possible  opportunity  has  repeatedly 
failed  to  save  life  in  cases  of  this  class.  All  this  would 
certainly  show  that  persons  afflicted  with  goitre  are  not 
to  be  dismissed  with  some  consoling  words  in  regard  to 
the  innocuousness  of  their  tumors,  but  that  their  disease 
constitutes  a  legitimate  cause  for  timely  remedial  inter- 
ference. 

The  kind  of  treatment  must  necessarily  vary  with  the 
nature  of  the  thyroid  swelling.  Parenchymatous  goi- 
tre should  never  be  confounded  in  this  respect  with  the 
cystic  variety.  In  the  former,  treatment  by  iodides, 
both  externally  and  internally,  is  always  advisable  before 
recourse  is  had  to  more  energetic,  but  also  more  dan- 
gerous therapy.  Experience  has  shown  that  iodides  will 
prove  of  decided  and  lasting  benefit  only  in  those  cases 
where  marked  effects  quickly  follow  their  first  use. 

Parenchymatous  injections  of  iodine  are  at  times  very 
efficacious.  But  it  is  to  be  borne  in  mind  that  they  are 
not  without  danger.  Fatal  consequences  have  resulted 
in  more  cases  than  one.  The  only  radical  measure  of 
relief,  however,  consists  in  removal  of  the  offending 
tumor.  For  all  other  operative  procedures  have  been 
found  to  involve  greater  dangers  and  extend  smaller 
chances  of  success  than  extirpation. 

Cystic  goitre  is  not  amenable  to  treatment  by  the 
iodides.  Puncture  of  the  cystic  cavities,  followed  by  the 
bjection  of  tincture  of  iodine,  has  been  found  to  succeed 
in  some  cases.  Billroth,  indeed,  claims  twenty-nine  cures 
out  of  a  whole  number  of  thirty-five  cases  treated  in  this 
way  by  him.  From  a  careful  study  of  a  large  number  of 
cases  of  this  class  Bruns  concludes  that  patients  showing 
signs  of  disturbed  lar3mgeal  innervation  should  not  be 
subjected  to  treatment  by  injection.  As  regards  the 
operation  of  extirpation,  the  author  pronounces  it  almost 
devoid  of  danger  in  uncomplicated  benign  struma.  But 
he  warns  against  complete  removal  of  the  thyroid  body. 
For  wherever  and  whenever  this  was  done,  a  typical  con- 
dition was  sooner  or  later  developed  in  the  patient.  It 
has  been  quite  aptly  termed  by  Kocher  cachexia  strumi- 
priva.  The  most  prominent  symptoms  of  the  latter  con- 
sist in  severe  progressive  cachexia,  leading  to  a  creti- 
noid condition  of  the  sufferer,  who  soon  shows  a  char- 
acteristic puffiness  of  the  face.     In  addition  there  are 


alterations  of  the  skin,  general  weakness,  and  decided 
awkwardness  in  all  movements,  without  any  diminution 
of  muscular  power,  however,  and  finally,  a  pronounced 
loss  of  mental  capacity. 

From  an  analysis  of  this  group  of  symptoms  a  remark- 
able resemblance  to  myxcedema  becomes  at  once  ap- 
parent. Add  to  this  the  fact  that  in  m3rxoedema  the 
thyroid  body  commonly  atrophies,  and  the  similitude 
seems  still  closer.  Of  course  explanatory  facts  are  en- 
tirely wanting  to  account  for  either  the  spontaneous 
development  of  myxcedema  or  the  supervention  of 
strumous  cachexia  after  total  extirpation  of  the  thyroid. 
Various  hypotheses  have  been  advanced,  but  their  dis- 
cussion here  would  seem  unprofitable. 

As  the  final  practical  consequence  of  the  most  recent 
experience  with  struma  it  may  be  said  that  partial  ex- 
cision should  always  be  practised.  And  in  the  individ- 
ual case,  before  attempting  operative  interference,  the 
surgeon  should  make  sure  that  a  portion  of  the  gland  can 
be  left  in  situ.  Total  extirpation  of  the  thyroid  body,  on 
the  other  hand,  should  never  be  performed.  For  it  is 
physiologically  unjustifiable,  arid  should  once  for  all  be 
stricken  from  the  list  of  permissible  operations. 


AN    INTERNATIONAL    HEALTH    EXHIBITION    IN    NEW 
YORK. 

The  International  Health  Exhibition  at  London  closed 
on  October  30th.  During  its  continuance  from  May  to 
November  there  was  a  grand  total  of  4,167,000  visitors, 
or  37,000  per  diem.,  and  both  from  a  financial  and  pop- 
ular point  of  view  it  was  one  of  the  most  successfiil 
exhibitions  ever  held  in  any  country.  This  was  due  in  a 
large  measure  to  the  concerts,  restaurants,  and  various 
other  "  side-shows ; "  but  despite  all  these  the  sanitary 
exhibits  attracted  much  attention,  and  unquestionably  a 
powerful  impulse  was  given  to  sanitary  studies  and  a 
knowledge  of  healthful  living.  The  library  of  7,000  vol- 
umes was  very  extensively  used,  lectures  and  conferences 
upon  sanitary  subjects  were  well  attended,  good  work 
was  done  at  the  biological  laboratory,  while  the  very 
practical  and  objective  teaching  of  the  insanitary  houses 
and  similar  exhibits  could  hardly  fail  to  have  impressed 
the  most  obtuse. 

The  exhibition  conveys  a  lesson  to  Americans  which 
we  cannot  believe  will  be  long  ignored.  There  should 
be  a  sanitary  exhibition  in  this  country,  and  in  no  part  of 
the  country  more  appropriately  than  in  New  York  City. 

We  believe  that  America  is  ripe  for  such  an  enterprise. 
Sanitary  problems  have  been  studied,  sanitary  organiza- 
tions established,  and  sanitary  literature  read  more  and 
more  every  year.  The  approach  of  the  cholera  has 
awakened  a  keen  interest  in  the  subject  of  municipal 
hygiene  and  maritime  quarantine,  and  this  interest  will 
not  subside  until  the  danger  is  over  or  the  epidemic  has 
come  and  gone.  The  fact  that  the  London  exhibition 
was  not  only  a  popular  success  but  that  it  might  even  be 
said  that  there  is  money  in  it  will  appeal  with  force  to 
the  minds  of  our  money-getting  countrymen.  Apart 
from  this  there  is  economy  in  spreading  abroad  a  knowl- 
edge of  hygiene  and  inoculating  the  average  mind  with 
irrefragable  proofs  that  healthfulness  is  worth  working 
for  and  paying  for.  Let  us  have  an  International  Hy. 
gienic  Exhibition  in  the  United  States. 


6o4 


THE   MEDICAL   RECORD. 


[November  29,  1884. 


^ews  0f  thz  WSie&U. 


What  is  the  CoRREcr  Name  for  the  New  Local 
ANiESTHETic  ?— Dr.  D.  K.  Shute,  of  Washington,  writes : 
'*  It  strikes  me  that  the  correct,  technical  name  for  this 
drug  is  'chloride  of  cocaine.'  In  an  editorial  of  The 
Record  for  November  8th,  it  is  stated  that  *  cocaine 
unites  easily  with  dilute  acids  to  form  crystallizable  salts,' 
therefore,  if  it  unites  with  dilute  hydrochloric  add  it 
forms  a  crystallizable  salt,  which  crystallizable  salt  is  a 

*  binary  compound '  and  no/  a  *  ternary '  one.  Modem 
scientific  works  on  chemistry  make  the  characteristic 
termination  of  'binary  compounds'  »ide  and  not  -a/e, 

*  Ternary  compounds '  have  the  characteristic  termination 
-o/^.  A  scientific  chemist  never  speaks  of  the  *  hydro- 
chlorate  of  ammonia '  as  the  result  of  the  combination  of 
hydrochloric  acid  (HCl)  and  ammonia  (NH.) ;  but  he 
calls  the  resulting  compound  chloride  of  ammonia  or  am- 
monium chloride  (NH.HCl)  or,  more  properly,  NH^Cl). 
It  is  no  more  correct  to  say  hydrochlorate  of  morphine, 
or  hydrochlorate  of  cocaine,  than  it  is  to  say  hydro- 
chlorate  of  ammonia.  The  result  of  the  union  of  cocaine 
(C„H,jNOJ  and  hydrochloric  acid  (HCl)  is,  as  stated 
above,  a  *  binary  compound.'  Therefore,  to  be  correctly 
specified,  this  *  binary  compound '  should  be  written  co- 
caine chloride  (C„H„N0,C1).  It  is  proper  to  say  sul- 
pho/^  or  nitr^/^  of  cocaine,  because  the  union  of  nitric 
and  sulphuric  acids  with  cocaine  forms  'ternary  com- 
pounds.' I  write  these  few  lines  in  the  hope  that  a  drug 
having  such  brilliant  properties  may  be  dignified  by  being 
called  by  its  proper  scientific  name,  viz.,  cocaine  chloride, 
chloride  of  cocaine,  or  cocainae  chloridum." 

The  Hospitals  in  New  York  Bay  have  been  sadly 
in  need  of  repair.  The  last  Legislature  stupidly  refused 
to  appropriate  money  for  the  purpose,  but  through  the 
energy  of  the  Health  Officer  and  the  liberality  of  the 
steamship  companies,  three  [thousand  dollars  was  se- 
cured, and  work  is  now  in  progress.  Yellow  fever  cases 
go  to  Swinburne  Island,  small-pox  and  cholera  to  Hoff- 
man Island. 

Prior  and  Finkler  vs.  Koch. — While  expressing  as 
we  have  done  elsewhere  our  great  confidence  in  the  su- 
perior skill  and  absolute  trustworthinessiof  Koch,  it  is 
impossible  to  deny  any  credit  to  the  entirely  antagonistic 
views  regarding  the  diagnostic  and  pathogenetic  signifi- 
cance of  the  comma-bacillus  expressed  by  Finkler  and 
Prior.  A  correspondent  of  the  Allgemeine  Medicinische 
Central'Zeitung  of  November  8th,  writes  from  Genoa 
under  date  of  October  ist  and  states  that  Professor 
Finkler  and  Dr.  Prior,  of  Bonn,  have  just  finished  their 
cholera  studies  at  the  Laboratory  of  the  St  Andreas  Hos- 
pital. He  says  :  "  The  view  maintaining  the  morpho- 
logical similarity  of  the  comma-bacillus  and  spirillum  of 
Asiatic  and  sporadic  cholera  has  been  beyond  question 
confirmed.  So  far  as  experiments  here  could  determine, 
no  difference  in  the  cultures  was  observable.  The  va- 
rious preparations  of  both  kinds  of  bacilli  show  such  a 
resemblance  that  no  specialist  could  determine  by  micro- 
scopic examination  the  difference  between  Asiatic  chol- 
era and  cholera  nostras.  By  changes  in  methods  of  cul- 
ture  marked  differences   in  the  form  and  size  of  both 


kinds  of  bacilli  may  be  produced.  The  pretended  dif- 
ference between  the  very  thin  bacilli  of  Asiatic  cholera 
and  the  plump  bacilli  of  cholera  nostras  is  entirely  arti- 
ficial and  not  of  the  slightest  importance." 

These  statements  are  utterly  at  variance  with  the  re- 
cent announcement  of  Koch.  We  can  only  say  at  pres- 
ent that  Koch  is  an  investigator  of  long  experience  and 
established  repute.  Finkler  and  Prior  are  new  in  the 
field,  and,  furthermore,  the  report  above  quoted  is  anon- 
ymous and  unofficial. 

Notes  on  the  Use  of  Cocaine. — ^The  Baltimore 
Surgeons  have  been  using  cocaine  extensively  in  eye  and 
venereal  diseases.  The  reports  are  as  enthusiastic  as  any 
published  in  this  city.  Dr.  Michael  found  it  very  useful 
in  opening  buboes  and  cauterizing  venereal  sores. 

Dr.  E.  E.  Holt,  of  Portland,  Me.,  reports  successful 
application  of  cocaine  in  eye  cases  {Boston  Medical  and 
Surgical  Journal).  Dr.  W.  E.  Ground,  of  Toledo,  0., 
has  also  had  uniform  success  with  the  drug. 

In  Vienna  the  drug  is  being  more  and  more  used. 
Recent  reports  upon  it  have  been  made  by  v.  Schrotter, 
Storck,  Konigstein,  and  Jelinck.  The  solutions  employed 
are  stronger  (ten  to  twenty  per  cent.)  than  those  which 
have  been  found  adequate  here.  England  and  France 
have  as  yet  had  little  to  say  about  it,  but  wherever  used 
the  reports  are  unanimous  in  its  favor. 

Mr.  Vanderbilt's  Gift. — The  letter  of  Mr.  William 
H.  Vanderbilt,  announcing  his  munificent  gift  of  $500,- 
000  to  the  College  of  Physicians  and  Surgeons  has  been 
made  public.  Mr.  Vanderbilt  says  in  his  letter,  which 
is  dated  October  17,  1884 : 

"  The  health,  comfort,  and  lives  of  the  whole  commu- 
nity are  so  dependent  upon  skilled  physicians  that  no 
profession  requires  more  tare  in  the  preparation  of  its 
practitioners.  Medicine  needs  a  permanent  home  where 
the  largest  opportunities  can  be  afiforded  for  both  theory 
and  practice.  It  seems  wiser  and  more  practical  to  en- 
large an  existing  institution,  which  already  has  great  fa- 
cilities, experience,  and  reputation,  than  to  form  a  new 
one.  I  have  therefore  selected  the  College  of  Physi- 
cians and  Surgeons  because  it  is  the  oldest  medical  school 
in  the  State  and  of  equal  rank  with  any  in  the  United 
States.  I  have  decided  to  give  the  College  $500,000,  of 
which  I  have  expended  $200,000  in  the  purchase  of  29 
lots  situated  at  Tenth  Avenue  and  Fifty-ninth  and  Six- 
tieth Streets,  the  deed  of  which  please  find  herewith; 
and  in  selecting  this  location  I  have  consulted  with  your 
Treasurer,  Dr.  McLane.  The  other  $300,000  (please 
find  inclosed  my  check  for.  The  latter  sum  is  to  form  a 
building  fund  for  the  erection  thereon  from  time  to  time 
of  suitable  buildings  for  the  college." 

The  Price  of  Quinine  is  now  about  one  dollar  an 
ounce,  but  some  druggists  continue  to  charge  at  the  rate 
of  three  or  four  dollars. 

The  Cholera  in  Paris  was,  at  last  reports,  abating. 
A  cable  report  to  the  New  York  Times  says:  The 
cholera  has  been  handled  very  well  in  Paris.  A  laige 
majority  of  the  cases  in  the  hospitals  have  been  cured. 
The  difficulty  with  the  remainder  has  been  either  that 
the  patient's  system  had  already  been  ruined  by  alcohol 
or  privation,  or  that  the  patient  arrived  at  the  hospital  too 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


605 


late.  The  latter  is  really  the  chief  trouble  everywhere. 
Dr.  Chapman's  treatment  with  ice-bags  on  the  spine  and 
Dr.  Hayem's  venous  injections  of  a  salt  solution  have 
both  been  successful.  The  old  wrangle  for  and  against 
Dr.  Koch's  theory  continues,  with  the  tendency  to  dis- 
credit it  rather  stronger  than  the  contrary  tendency. 

The  Value  of  the  Hospital  Collections. — In  an- 
swer to  a  charge  that  the  Hospital  Saturday  and  Sunday 
collections  have  been  an  absolute  detriment  to  the  Lon- 
don hospitals,  because  of  the  diminished  voluntary  contri- 
butions at  other  times,  the  Secretary,  Mr.  Baker  says  : 
So  far  as  Hospital  Sunday  in  New  York  is  concerned,  it 
cannot  be  regarded  otherwise  than  as  a  movement  result- 
ing in  almost  unmixed  good.  From  the  annual  state- 
ments of  the  Associated  Hospitals  it  is  seen  :  i,  That  dur- 
ing the  past  three  years  $201,651.44  was  expended  on 
the  enlargement  of  accommodations ;  2,  that  there  has 
been  an  increase  of  $9,780.12  in  the  income  from  in- 
vested funds ;  3,  that  there  has  been  an  increase  of 
$43,036. 73  from  paying  patients,  at  the  same  time  that 
the  number  of  free  patients  treated  has  increased  from 
6,698  in  1881  to  7,188  in  1883  ;  while,  4,  the  increase  of 
income  from  contributions  toward  current  expenses  other 
than  derived  from  the  Saturday  and  Sunday  collection  is 
represented  by  $22,774.84. 

The  Quack  Triumphant, — Despite  much  talk  and 
protestations,  Professor  Schweninger  has  begun  his  duties 
at  the  Charite  Hospital,  Berlin. 

The  Carnegie  Laboratory. — We  learn  that  Dr. 
Paul  Grawitz  has  been  unable  to  accept  the  position  of 
Director  of  the  Carnegie  Laboratory  and  Professor  of 
Pathological  Anatomy  at  Bellevue  Hospital  Medical 
College. 

Monument  to  the  Late  Professor  Cohnheim. — 
The  friends  and  pupils  of  the  late  Professor  Cohnheim 
are  arranging  to  collect  funds  for  the  purpose  of  erecting 
a  monument  to  the  memory  of  the  deceased  pathologist. 

At  the  Recent  Examinations  for  the  Externat 
in  the  Paris  hospitals  there  were  347  applicants,  among 
whom  were  6  women  and  i  Turk. 

Australia  Refuses  to  Recognize  American  Medi- 
cal Diplomas. — The  Queensland  Medical  Board  has 
passed  a  resolution  refusing  to  register  American  diplo- 
mas, unless  the  professional  knowledge  of  their  holders 
is  certified  to  by  the  passage  of  an  examination  at  either 
of  the  Universities  of  Melbourne  or  Sydney.  **  It  is  much 
to  be  regretted,"  says  the  Australian  Medical  Gazetity 
"that  there  is  not  sufficient  backbone  in  the  other  colo- 
nies to  take  a  similar  firm  stand.  The  longest  time  re- 
quired by  the  American  colleges  to  be  passed  in  study 
before  the  candidates  are  admitted  for  examination  is 
three  years,  twelve  months  less  than  the  shortest  time 
required  in  the  United  Kingdom."  It  is  to  be  regretted 
that  Australians  do  not  temper  wisdom  with  their  firm- 
ness and  refuse  registration  only  to  colleges  whose  cur- 
riculum and  requirements  are  below  a  good  standard. 

The  Prudent  Physicians  of  Italy. — Dr.  A.  La- 
gorio,  writing  from  Chiavari  to  the  Chicago  Medical 
Journal  and  Examiner^  relates  some  facts  that  may 
have  a  pertinent  bearing  here.     He  says  :  "  At  the  first 


outbreak  of  the  epidemic  in  Italy  the  Government  made 
an  earnest  appeal  to  physicians  to  volunteer  their  work 
and  skill  in  suppressing  the  disease  and  in  treating  its 
victims.  This  appeal  had  very  little  effect,  for  few  re- 
sponded ;  but  through  the  presidents  of  the  several  med- 
ical societies  of  the  State,  our  physicians  assured  the 
Government  that  they  were  willing  to  risk  their  lives  as 
sanitarians  and  citizens ;  but,  before  doing  so,  they  asked 
for  a  law  making  them  equal  to  officers  of  the  army,  so 
that  if  the  Government  desired  them  to  sacrifice  their 
lives  for  the  public  health,  it  should  assure  them  that 
their  families  would  not  have  to  suffer  without  receiving 
a  suitable  pension.  The  Government  has  not  yet  taken  1 
the  matter  in  consideration."  For  physicians  with  a 
family  and  no  money  to  leave  for  them  such  a  proposi- 
tion does  not  seem  more  than  just.  We  shall  certainly 
advocate  the  giving  some  help  by  the  city  or  State  to  the 
families  of  poor  physicians  who  die  from  epidemic  dis- 
ease contracted  in  discharge  of  duty. 

A  New  Source  of  Lead-Poisoning. — Dr.  Edson,  of 
the  Health  Department  of  this  city,  has  unearthed  a  new 
food  adulteration  quite  startling  in  character,  namely,  the 
coloring  of  vermicelli  with  chrome  yellow,  a  pigment  con- 
taining lead,  used  for-  this  purpose  in  lieu  of  eggs  and 
saffron.  Dr.  Waller,  chemist  to  the  Department,  analyzed 
a  number  of  samples  of  vermicelli  colored  in  this  man- 
ner, and  found  in  them  an  average  of  three  grains  of 
metallic  lead  to  the  ounce  of  food  1  Six  manufacturers 
of  the  stuff  were  arrested  and  promptly  fined  at  the 
Court  of  Special  Sessions.  The  counsel  defending  them 
mov^d  to  have  the  cases  dismissed  because  the  Health 
Officers  were  unable  to  cite  a  single  case  where  lead 
poisoning  had  been  caused  by  vermicelli.  The  defence 
also  brought  witnesses  who  swore  that  they  had  eaten 
vermicelli  colored  with  chrome  yellow  for  long  periods 
without  injury.  The  publicity  given  the  subject  has, 
since  the  trial,  brought  to  light  one  case  of  lead  poison- 
ing, the  cause  of  which  had  been  hitherto  unexplained, 
in  a  person  who  had  been  in  the  habit  of  daily  consuming 
a  quantity  of  vermicelli  purchased  from  a  dealer  whose 
stock,  subsequently  examined,  was  found  to  be  colored 
with  chrome  yellow.  Making  our  deductions  from  the 
amount  of  lead  found  in  the  vermicelli,  we  belieVe  that 
other  cases  of  poisoning  must  exist,  caused  by  this  prac- 
tice, not  recognized  because  practitioners  have  not  had 
their  attention  called  to  this  article  of  food  as  a  possible 
source  of  lead-poisoning. 

The  Bismuth  Test  for  Sugar. — Dr.  D.  Brown,  of 
this  city,  writes ;  "In  an  editorial  article  in  The  Record 
for  November  ist  you  call  attention  to :  *  A  New  Bismuth 
Test  for  Sugar,'  and  credit  its  discovery  and  introduc- 
tion to  Aimer  and  Nylander.  Permit  me  to  call  your 
attention,  to  the  fact  that  the  late  Professor  Rand,  of 
Jefferson  Medical  College,  taught  that  test  to  his  class 
in  1872 ;  and  you  will  also  find  it  in  his  students'  text- 
book, published  the  same  year  (see  '  Elements  of 
Chemistry,*  pp.  373).  Should  he  not  therefore  have 
priority?" 

The  Privacy  of  Hospital  Records. — Dr.  J.  P. 
Fessenden,  of  Salem,  sends  us  a  reply  to  the  Superinten- 
dent of  St.  Luke's  Hospital,  but  we  are  unable  to  give 
further  space  to  the  controversy. 


6o6 


THE   MEDICAL  RECORD. 


[November  29,  1884. 


The  Intelligent  Interest  in  Medical  Affairs 
displayed  by  the  daily  press  is  strikingly  illustrated  in  the 
following  description  taken  from  a  daily  ptper  of  this 
city :  '*  For  several  years  the  physicians  of  this  State  have 
been  considering  the  advisability  of  holding  an  anniuJ 
meeting  for  the  purpose  of  bringing  together  in  consulta- 
tion the  leading,  members  of  the  profession.  The  plan 
took  form  some  time  ago.  This  morning  representatives 
from  every  section  of  the  State  assembled  for  the  purpose 
of  holding  the  first  annual  session."  We  are  then  told 
that  Dr.  Didman  is  President,  Dr.  Henton,  Treasurer, 
and  that  Dr.  Austin  Flinn,  Jr.,  was  among  the  members 
present.    More  care  is  exercised  in  reporting  glove  fights. 

Some  Interesting  Facts  Regarding  the  Mainte- 
nance OF  Sick  Seamen. — ^Seamen  who  may  require  sur- 
gical or  medical  attendance  by  reason  of  accident  or 
disease,  while  employed  on  all  classes  of  vessels,  are  at 
liberty  to  go  either  to  a  United  States  Marine  Hospital, 
where  the  Government  bears  all  the  expense,  or  to  call 
in  the  best  outside  surgical  and  medical  attendance  in 
the  country,  and  the  owners  of  the  vessel  are  by  law 
compelled  to  pay  the  bills.  Therefore,  if  the  Congress- 
ional appropriations  for  the  maintenance  of  the  Marine 
Hospital  Service  should  give  out,  and  the  hospitals  were 
closed  up,  all  the  sick  and  disabled  sailor  would  have  to 
do  would  be  to  put  himself  in  charge  of  a  first  class  doc- 
tor, who  would  have  no  difficulty  in  collecting  his  usual 
and  legitimate  fees  from  the  vessel  owner.  *'The  repeal 
of  the  Marine  Hospital  tax,"  says  The  Nautical  Gazette^ 
''has  opened  a  new  field  for  impecunious  physicians,  and 
we  may  soon  see  our  water-front  graced  by  runners  for 
doctors,  just  as  runners  solicit  business  for  tow-boats, 
ship  chandlery,  etc."  "Already  two  respectable  phy- 
sicians have  called  our  attention  to  this  condition  of 
affairs,  by  requesting  us  to  furnish  them  with  copies  of 
The  Nautical  Gazette  in  which  was  published  a  recent 
decision  of  a  United  States  court  upholding  the  constitu- 
tional right  of  a  sick  seaman  to  be  cared  for  by  a  physi- 
cian of  his  own  choice,  in  a  large  seaport  where  the 
United  States  Marine  Hospital  had  a  corps  of  surgeons 
and  one  of  the  most  perfect  hospitals  in  the  country.' ' 

Dr.  W.  M.  Fuqua,  of  Hopkinsville,  Ky.,  has  been 
recently  elected  to  the  Chair  of  Anatomy  in  the  Memphis 
Hospital  Medical  College. 

Sir  Spencer  Wells  on  the  Revival  of  Ovariot- 
omy.— Sir  Spencer  Wells,  in  an  address  delivered  at  the 
opening  of  the  Midland  Medical  Society  on  the  revival  of 
ovariotomy  and  its  influence  upon  modern  surgery,  gives 
the  following  interesting  risumi  of  the  subject :  "  Before 
1858,  the  operation,  like  all  good  things,  had  been  of 
slow  growth.  One  hundred  years  ago  it  was  but  a  germ 
that  might  be  descried  in  a  lecture  by  John  Hunter. 
Ten  years  later  it  was  seed  that  fell  from  the  hand  of 
Bell.  In  little  more  than  another  decade  it  germinated 
as  a  living  vitalizing  reality  in  Kentucky.  Sixty  years 
ago  it  was  transplanted  to  the  land  of  its  philosophical 
conception.  In  twenty  years  more  we  find  it  a  sapling 
on  English  soil — ^growing  slowly  at  first,  and  up  to  1858 
looking  as  if  it  might  prove  no  more  than  a  withering 
gourd.  But  by  1865  its  root  had  struck  firm,  its  stem 
stood  erect,  its  branches  were  wide  and  strong,  known 
and  sought  as  a  refuge  by  the  sick  and  dying.     That  it 


was  no  withering  gourd  has  been  proved  by  all  that  the 
world  has  since  seen.  Thousands  of  perishing  women 
have  been  rescued  from  death  ;  many  more  thousands  of 
years  of  human  life,  health,  enjoyment,  and  usefulness 
have  been  given  to  the  race  ;  and  to  all  future  victims  of 
a  malady  before  inevitable  in  its  fatality,  it  gives  conso- 
latioDy  hope,  and  almost  certainty  of  cure.'* 

Unapprkoated  Opportunities  for  Young  Physi- 
cians.— It  is  a  somewhat  curious  fact  that  for  a  number 
of  years  there  have  be«n  a  considerable  number  of  vacan. 
cies  both  in  the  Army  and  Navy  Medical  Departments] 
The  Examining  Boards  meet  again  and  again,  but  appli. 
cants  do  not  come  in  sufi[icient  numbers  or  with  sufficient 
preparation  to  fill  the  vacant  positions.  It  is  difficult  to 
understand  why  so  many  young  men  prefer  long  yean 
of  hard  work  and  impecuniosity  to  the  immediate  receipt 
of  a  handsome  salary  and  a  good  position. 

Deaths  from  Cholera  in  New  York  in  Past  Epi. 
DEMics, — Dr.  John  T.  Nagle  reports  that  in  1832  there 
were  3,513  deaths  firom  cholera  in  this  city,  at  the  rate 
of  15.64  in  every  1,000  persons.  In  1849  there  were 
5,071  deaths,  or  11.24  P^r  cent.  In  1854  there  were 
3i5o7  people  died,  or  3.95  per  cent.  In  1866  the  deaths 
were  1,137,  an  average  of  1.28  per  cent.  The  epidemic 
of  1866  was  of  a  virulent  type,  583  persons  who  died 
having  been  attacked  in  the  streets. 


THE  SIMS  MEMORIAL  FUND. 

To  the  Medical  Profession  and  Others  throughout  1k% 
World: 

The  great  achievements  of  Dr.  J.  Marion  Sims  call 
for  some  more  lasting  testimonial  than  obituaries  and 
eulogies.  To  him  medical  science  is  indebted  for  mnch 
brilliant  and  original  work,  especially  in  gynecological 
surgery.  Those  who  have  been  benefited  by  his  teach- 
ings and  new  operations,  and  such  as  have  had  the  direct 
advantage  of  his  personal  skill  are  among  the  first  to 
recognize  and  acknowledge  this  debt 

To  him  is  due  the  honor  of  giving  the  first  strong  im- 
pulse to  the  study  of  gynecological  surgery  in  America. 

It  is  believed  diat  the  medical  profession  everywhere, 
the  vast  number  of  women  who  owe  their  relief  fix)m 
suflfering  directly  to  him,  and  those  who  realize  the 
benefits  he  first  made  possible,  will  gladly  unite  thus  to 
honor  the  man  through  whose  originsd  and  inventive  ge- 
nius such  blessings  have  been  conferred  upon  humanitj. 

At  the  suggestion  of  many  fiiends,  therefore,  the  sab- 
joined  committee  has  been  organized,  and  it  is  proposed 
that  a  suitable  monument  be  erected  to  his  memory  in 
the  city  of  New  York. 

To  this  end  the  active  co-operation  of  the  medical 
profession  and  the  many  other  fiiends  of  Dr.  Sims 
throughout  the  world  is  respectfiiUy  solicited.  Contribu- 
tions of  one  dollar  and  upward  may  be  forwarded  to  the 
journal  which  has  been  constituted  the  treasury  of  this 
fund — The  Medical  Record,  New  York. 

FORDYCE  BARKER,  M.D.,  Chairman, 
GEORGE  F.  SHRADY,  M.D.,  Secretary^ 

Thomas  Addis  Emmet,  M.D.,  New  York. 

T.  Gaillard  Thomas,  M.D.,  " 

William  T.  Lusk,  M.D.,  '* 

William  M.  Polk,  M.D.,  « 

Paul  F.  MundA,  M.D.,  " 

S.  O.  Vander  Poel,  M.D.,  " 

Frank  P.  Foster,  M.D.,  " 

E.  S.  Gaillard,  M.D.,  " 


J^ovember  29,  1884*] 


THE  MEDICAL  RECORD. 


607 


Alex.  J.  C.  Skene,  M.D.,  Brooklyn,  N,  Y. 
Samuel  D.  Gross,  M.D,,  Philadelphia,  Pa. 
William  Goodell,  M.D.,  " 

James  R,  Chadwick,  M.D,,  Boston,  Mass; 
William  H.  Byford,  M.D.,  Chicago,  lU. 
A.  Reeves  Jackson,  M.  D.,       " 
Thad.  a.  Reamy,  M.D.,  Cincinnati,  O. 

C.  D.  Palmer,  M.D.,  " 

George  J.  £ngelmann,  M.D.,  St.  Louis,  Mo. 
R.  Beverley  Cole,  M.D.,  San  Francisco,  CaL 
H.  F.  Campbell,  M.D.,  Augusta,  Ga. 
R.  B.  Maury,  M.D.,  Memphis,  Tenn. 
E.  S.  Lewis,  M.D.,  New  Orleans,  La. 
J.  T.  Searcy,  M.D.,  Tuskaloosa,  Ala, 
R.  A.  KiNLOCH,  M.D.,  Charleston,  S.  C. 
Hunter  Maguire,  M.D.,  Richmond,  Va. 
S.  C.  BusEY,  M.D.,  Washington,  D.  C. 
Harvey  L.  Byrd,  M.D.,  Bdtimore,  Md. 
W.  T.  Howard,  M.D.,  " 

D.  W.  Yandell,  M.D.,  Louisville,  Ky. 
Seth  C.  Gordon,  M.D.,  Portland,  Me. 
Frank  E.  Beckwith,  M.D.,  New  Haven,  Conn. 
A.  W.  Knox,  M.D.,  Raleigh,  N.C. 

L.  W.  Oakley,  M.D.,  Elizabeth,  N.  J. 
A.  T.  Woodward,  M.D.,  Brandon,  Vt. 
Albert  H.  Crosby,  M.D.,  Concord,  N.  H. 

E.  8.  DuNSTER,  M.D.,  Ann  Arbor,  Mich. 
Alex.  J.  Stone,  St.  Paul,  Minn. 


Additional  List  of  Subscriber^. 

F.  Seraeleder,  M.D.,  City  of  Mexico $10  00 

P.  A.  Morrow,  M.D.,  New  York 25  00 

Ellsworth  Eliot,  M.D.,         "        5  00 

J.  H.  Fruitnight,  M.D.,        '*          5  00 

J.  W.  Bond,  M.D.,  Toledo,  Ohio 5  00 

C.  A.  Kirkley,  M.D.,     ''           *»     5  00 

A.  N.   Ellis,    M.D.,  Hamilton,  Ohio i  00 

C.  Falconer,  M.D.,           "              "     100 

C.  A.  L.  Reed,  M.D.,         "              "     i  00 

Dan.  Millikin,  M.D.,         "              "     i  00 

Geo.  C.  Skinner,  M.D.,      "              '*     i  00 

H.  Mallory,  M.D.,             "              "     i  00 

W.  H.  Scobey,  M.D.,          "              "     i  00 

A.  Myers,  M.D.,                 "              "     i  00 

G.  W.  PuUen,  M.D.,  Logan,  Ohio 5  00 

J.  H.  Dye,  M.D.,           "          "     100 

H.  J.  Donahoe,  M.D.,  Sandusky,  Ohio 5  00 

A.  J.  Gawne,  M.D.,               "            "    2  00 

Wm.  Story,  M.D.,  Costalia,  Ohio 2  00 

F.  C.  McConnelly,    M.D.,  Vermillion,  Ohio  ....  5  00 

Au  E.  Meerull,  M.D.,  Sandusky,  Ohio 2  00 

A.  E.  Heighway,  M.D.,  Cincinnati,  Ohio i  00 

F.  Forcheimer,  M.D.,             "              "     5  00 

Jos.  Ransohoflf,  M.D.,             "              "     5  00 

Jas.  T.  Whittaker,  M.D.,         "              "     5  00 

R.  L.  Sweney,  M.D.,  Marion,  Ohio i  00 

D.  N.  Keusman,  M.D.,  Columbus,  Ohio i  00 

H.  J.  Shajrp,  M.D.,  London,  Ohio i  00 

H.  G.  Landis,  M.D.,  Columbus,  Ohio i  00 

John  N-  Beach,  M.D.,  W.  Jefferson,  Ohio i  00 

W.^  C.  Denman,  M.D.,  Marion,  Ohio i  00 

John  Carson,  M.D.,  Middletown,  Ohio 5  00 

Thad.  A.  Reamy,  M.X).,  Cincinnati,  Ohio 100  00 


glewiexirs  mifSi  ^otijcjes* 


The  Question  of  Priority  in  the  Use  of  Forceps 
in  Breech  Presentation.  —  Dr.  H.  T.  Dunbar,  of 
Union,  N.  Y.,  sends  us  the  title-page  of  a  pamphlet  en- 
titled **  The  Forceps  in  Breech  Deliveries,  with  a  De- 
scription of  a  New  Instrument,  by  A.  J.  Miles,  M.D., 
Professor  of  Diseases  of  Women  and  Children  in  the 
Cincinnati  College  of  Medicine  and  Surgery. '^  It  is  taken 
from  the  '*  Transactions  of  the  Ohio  State  Medical  Soci- 
ety for  1876."  Dr.  Miles  antedates  Dr.  Fruitnight,  there- 
fore, by  a  year  or  more. 


Daniel  Gohl  und  Christian  Kundmann.  Zur  Ge- 
schichte  der  Medicinal-Statistik.  Von  Dr.  J.  Graetzer. 
Pp.  155.  Breslau :  S.  Schottlaender.  1884. 
The  author,  Dr.  Graetzer,  gives  a  history  of  the  origin  of 
medical  statistics,  and  an  account  of  the  lives  and  works 
of  Gohl  and  Kundmann,  the  fathers  of  this  science.  The 
work  is  well  printed  and  will  be  of  much  interest  to  stat- 
isticians and  sanitarians. 

Die    Zuckerharnruhr    mit    einer    ausfI^hrlichen 

DiATETIK     FtiR     ZUCKERKRANKE.      Vou    UnIV.    MeD. 

Dr.  Emerich  Hertzka.  No.  i,  Svo,  pp.  181.  Karls- 
bad und  Nizza :  Feller's  Didtetische  Fiihrer, 
This  is  the  first  of  a  series  of  "  Diet  Guides "  which 
promise  to  be  very  useful.  Dr.  Hertzka  has  given  us  a 
very  complete  monograph  on  the  diabetes  mellitus,  its 
etiology,  symptomatology,  progress,  complications,  and 
treatment  It  will  be  a  useful  work  to  those  who  have 
these  cases  under  treatment. 

De   la  REPARTITION  DU   SaNG  CIRCULANT   DANS  L'£cO- 

nomie.     Par  le  Docteur  ^mile  Spehl.    Th^se  d'A- 
gr6gation,  pr^sent^  ^  la  Faculty  de  M^decine  de  Bru- 
xelles.    Bruxelles:  A.  N.  Leb^gue  &  Cie.    1883.    The 
Distribution  of  the  Circulating  Blood  in  the 
Economy.     8vo,  pp.  230. 
This  doctorate  thesis  represents  a  series  of  elaborate  in* 
vestigations  into  the  distribution  of  the  circulating  blood 
in  the  brain,  lungs,  and  muscles.     The  author  has  ob» 
tained  some  definite  figures  to  represent  the  fact  that  the 
three  organs  referred  to  have  more  blood  during  func- 
tional activity  than  during  rest.     Perhaps  his  most  inter- 
esting conclusion  is  that  an  environment  of  rarefied  air 
draws  the  blood  to  the  free  surface  of  the  lungs,  but  not 
of  the  skin. 


lljepartB  of  Jiajcietijes. 


MEDICAL  SOCIETY  OF  THE  COUNTY  OF  NEW 
YORK. 

Adjourned  Annual  and  Stated  Meetings  November  24, 
1884. 

The  adjourned  annual  meeting  was  called  to  order  by 
the  retiring  President,  Dr.  S.  Oakley  Vander  Poel, 
M.D.,  LL.D.,  who  delivered  the  customary  address,  in 
which  he  reviewed  the  work  done  by  the  Society  during 
the  last  year,  its  material  and  scientific  prosperity,  and 
introduced  his  successor  in  office. 

Before  resiuning  his  place  upon  the  benches  he  re- 
turned his  heartfelt  thanks  to  the  Society  for  the  uniform 
courtesy  which  had  marked  the  conduct  of  the  members 
toward  him  as  their  presiding  officer,  and  suggested  that 
more  time  be  given  to  the  discussion  of  the  papers  pre- 
sented to  the  Society. 

To  do  this  the  papers  should  not  partake  quite  so 
much  the  character  of  an  essay,  but  rather  be  directed  to 
the  elucidation  of  some  particular  point  or  method  in  the 
field  of  medicine  or  surgery.  Let  the  papers  be  short 
and  definite  in  purpose,  and  confined  chiefly  to  contro- 
verted points,  or  such  as  require  fuller  demonstration. 
The  same  rules  should  regulate  the  debate.  Nothing  is 
more  wearisome  than  a  rambling  debate  where  the  nar- 
ration of  opinion  and  experience  is  so  b'ttle  related  to 
the  actual  point  under  consideration.  The  remedy  for 
this  lies  in  the  Society. 

On  motion  by  Dr.  J.  C.  Peters,  the  Society  ex- 
tended to  Dr.  Vander  Poel  a  vote  of  thanks  for  the  faith- 
ful discharge  of  the  duties  of  president  during  his  term 
of  office. 

The  Society  then  adjourned. 


6o8 


THE  MEDICAL  RECORD. 


[November  29, 1884, 


Stated  Meeting, 

The  Stated  Meeting  was  called  to  order  by  the  Presi- 
dent, Dr.  Daniel  Lewis,  who  delivered  his  inaugural 
address,  in  which  he  first  expressed  the  deep  and  lasting 
obligations  which  the  Society  owed  to  his  distinguished 
predecessor.  He  also  expressed  himself  as  profoundly 
grateful  for  the  trust  which  the  Society  had  bestowed  upon 
him,  and  with  its  support  would  spare  no  effort  to  protect 
and  advance  its  important  interests. 

Special  reference  was  made  to  the  question  of  increas- 
ing the  membership  of  the  Society,  and  also  to  the  work 
of  enforcing  medical  laws.  The  suit  against  the  Ek:lectic 
Medical  College  is  of  such  importance  that  no  effort  must 
be  spared  to  win  the  case,  as  it  is  a  diploma  mill  of  such 
proportions  as  to  almost  rival  the  Buchanan  College  of 
Philadelphia. 

The  President  then  directed  attention  to  the  impor- 
tance of  having  State  Examining  and  Licensing  Boards. 

A  very  important  change  needed  was  a  provision  for 
revoking  a  license  to  practice. 

Attention  was  then  directed  to  the  propriety  of  at  once 
taking  steps  to  secure  a  more  commodious  place  for  hold- 
ing the  meetings  of  the  Society,  as  one  must  necessarily 
soon  be  secured  on  account  of  the  recent  good  fortune 
of  the  College  of  Physicians  and  Surgeons. 

At  the  close  of  the  address,  the  President  appointed  the 
following 

COMMITTEES   FOR   THE    ENSUING   YEAR. 

Committee  on  Hygiene — Dr.  Stephen  Smith,  Chairman ; 
Drs.  Alexander  Hadden,  E.  H  Janes,  Cyrus  Edson, 
Wm.  L.  Hardy. 

Committee  on  Ethics — Dr.  George  A.  Peters,  Chair- 
man ;  Drs.  W.  T.  Alexander,  Mark  Blumenthal,  C.  C. 
Lee,  E.  Waitzfelder. 

Committee  on  Prize  Essays — Dr.  F.  R.  Sturgis,  Chair- 
man ;  Drs.  Frank  P.  Foster,  W.  R.  Birdsall. 

Auditing  Committee, — Dr.  P.  Albert  Morrow,  Chair- 
man ;  Dr.  Gorham  Bacon. 

On  motion  by  Dr.  Vander  Poel,  that  portion  of  the 
President's  address  which  referred  to  change  of  place  of 
holding  the  meetings  was  referred  to  the  Comitia  Mi- 
nora, 

After  the  report  of  the  Comitia  Minora  Dr.  Simon 
Baruch  read  a  paper 

ON  THE  THIRD  STAGE  OF  LABOR, 

in  which  he  discussed  at  length  the  'three  plans  of  man- 
agement—namely, expectancy,  the  Dublin,  and  Credo's 
method,  and  the  method  which  occupies  a  middle  ground, 
and  which  had  been  the  most  fruithful  of  good  results. 

Each  plan  was  discussed  in  detail,  with  the  citation  of 
opinions  of  a  large  number  of  authorities,  and  also  sta- 
tistical information. 

Dr.  Baruch  regarded  the  expectant  plan  as  a  retro- 
grade step  in  the  management  of  the  third  stage  of  labor. 

He  also  believed  that  the  superiority  of  Credo's  method 
had  been  established  by  clinical  experience  and  statistics. 
This  method  he  regarded  as  a  prophylactic  against  reten- 
tion of  the  placenta  and  hemorrhage. 

Under  the  third  head  the  author  of  the  paper  discussed 
the  physiological  action  of  the  uterus  in  removing  the 
placenta,  consisting  of  tonic  contractions  for  its  separa- 
tion, and  clonic  contractions  for  its  expulsion. 

The  modification  which  he  advocated  consisted  mainly 
in  the  introduction  into  the  vagina  of  two  antiseptic 
fingers  to  retard  too  rapid  expulsion  of  the  placenta,  to 
aid  in  removing  it  during  a  pain,  and  to  secure  removal 
of  the  membranes  without  twisting,  and  in  the  interval 
between  pains. 

Dr.  Wm.  M.  Polk  was  invited  to  open  the  discussion, 
and  said  he  did  not  understand  how  any  man  could  wish 
to  relegate  Credo's  method  of  expressing  the  placenta  to 
the  useless  things  to  be  discarded.  He  was  heartily  in 
accord  with  Dr.  Baruch  in  his  warning  against  discarding 
this  method. 

Dr.  BaruchTiad  advised  that  the  chloroform  be  discon- 


tinued, at  the  last  period  of  the  second  stage,  and  to  that 
view  Dr.  Polk  took  exception  and  remarked  that  he  con- 
tinued its  use  until  the  head  of  the  child  was  expelled. 

Dr.  Polk  also  believed  that  no  harm  could  come  from 
twisting  the  membranes,  and  he  thought  that  by  so  doing 
their  delivery  could  be  expedited. 

Dr.  R.  a.  Murray  thought  that  the  method  practised 
by  most  accoucheurs  was  that  which  took  the  place  of 
Credo's  method ;  namely,  keeping  one  hand  firmly  upon 
the  fundus  of  the  uterus  as  the  child  was  expelled,  and 
with  delivery  following  the  uterus  down  and  retaining 
it  there  until  permanent  contraction  of  the  u terns  had 
taken  place.  He  believed  that  Credo's  method  was  ap. 
plicable  chiefly  in  those  cases  where  inertia  of  utenis 
existed  and  there  was  threatened  hemorrhage  from  chlo- 
roform, powerless  labors,  instrumental  interference,  etc. 

With  regard  to  twisting  the  membranes,  he  regarded  it 
as  most  important  in  delivering  the  placenta,  and  further, 
that  it  should  be  done  during  a  pain.  Aside  from  these 
two  points,  he  agreed  thoroughly  with  the  author  of  the 
paper. 

Dr.  Fruitnight  spoke  of  the  efficiency  of  the  modi- 
fication of  Credo's  method,  namely,  guarding  against  too 
rapid  expulsion  of  the  placenta,  but  he  practised  twisting 
of  the  membranes  and  believed  it  was  advantageous  to  do 
so.  Although  the  placenta  might  be  retained  within  the 
uterus  for  several  hours  without  doing  harm,  yet  he  re- 
garded it  as  a  foreign  body  and  one  which  should  be  re- 
moved as  soon  as  practicable. 

Dr.  Irwin  said,  concerning  the  practice  of  the  Dublin 
school,  that  while  the  general  sense  might  be  in  favor  of 
the  expectant  method,  yet  interference  was  not  precluded, 
as  active  as  might  be  necessary.  He  thought  the  Dublin 
school  could  not  be  spoken  of  as  either  an  interfering 
or  an  expectant  school,  but  one  which  acts  with  due 
knowledge  of  the  case  in  hand.  The  English  school 
advocated  less  interference  than  did  the  Dublin  school 
probably.  With  regard  to  twisting  the  membranes  he 
thought  there  could  be  no  doubt  concerning  the  pro- 
priety of  the  procedure  ;  pulling  on  the  membranes  was 
certainly  objectionable. 

Dr.  Malcolm  McLean  spoke  concerning  the  neces- 
sity of  inspecting  the  placenta  after  it  had  been  delivered. 

Dr.  Baruch  said  that  he  withheld  the  chloroform  only 
at  the  very  last  moment  of  the  second  stage  of  labor. 
He  objected  to  twisting  the  membranes  because  it  en- 
couraged pulling  upon  them.  He  objected  to  downward 
pressure  under  the  circumstances  mentioned  by  Dr. 
Murray,  because  it  had  been  claimed  that  the  Dublin 
method  might  produce  inversion  of  the  uterus.  He 
therefore  would  not  depend  uix)n  Cred6*s  method  in 
uterine  inertia  from  chloroform,  etc.  In  general  he 
thought  we  should  be  guided  less  by  individual  experi- 
ence than  by  the  results  in  well-recorded  cases  in  large 
numbers  carefully  watched. 

Dr.  Douglas,  Treasurer,  directed  attention  to  the  fui 
that  he  was  prepared  to  supply  the  members  with  copies 
of 
the  transactions  of  the  medical  society  of  the 

state 
at  one  dollar  a  copy. 

Dr.  Piffard  offered  the  following  resolutions,^hich 
were  adopted : 

register  of  members. 

Resolved^  That  a  committee  of  three  be  appointed  by 
the  President  to  prepare  a  register  of  the  members  of  this 
Society,  to  be  entitled,  "The  Register  of  the  Medical 
Society  of  the  County  of  New  York ; "  and  to  print  the 
same  and  distribute  it  to  members  without  charge,  said 
Register  to  contain  the  names  of  active  members,  to- 
gether with  their  addresses  and  office  hours. 

Resolved,  That  the  Comitia  Minora  be  requested  to 
make  the  necessary  appropriations  to  carry  the  above 
resolution  into  effect. 

The  Society  then  adjourned. 


November  29,  1884.] 


THE   MEDICAL  RECORD. 


609 


THE  PRACTITIONER'S  SOCIETY  OF  NEW 
YORK. 

Stated  Meetings  November  7,  1884. 

A.  B.  Ball,  M.D.,  President,  in  the  Chair. 

Dr.  George  F.  Shrady  read  a  paper  (see  p.  591)  on 

CASES    OF    strangulated    HERNIA,    WITH    REMARKS    ON 
TREATMENT. 

Dr.  a.  C.  Post  asked  Dr.  Shrady  if  he  stated  that  in 
several  of  the  cases  reported  no  hernial  tumor  existed 
before  the  s3rmptoms  of  strangulation  developed. 

Dr.  Shrady  replied  that  no  tumor  had  been  reported 
by  patients  in  two  cases  until  strangulation  occurred,  one 
of  the  patients  being  about  twenty,  and  the  other  about 
forty  years  of  age.  It  was  quite  evident  that  a  small 
hernia  had  existed  in  the  latter  case,  and  had  been  over- 
looked by  the  patient.  The  other  case  was  clearly  one 
of  strangulated  congenital  hernia,  the  sac  being  the  tunica 
vaginalis. 

Dr.  Post  believed  it  to  be  a  very  rare  occurrence  that 
a  hernia  was  strangulated  when  it  first  came  down,  except 
when  it  entered  the  tunica  vaginalis.     There  were  cases, 
usually  in  youn^  men,  in  whom  the  tunica  vaginalis  had 
not  yet  closed,  in  which,  from  a  violent  strain,  the  intes- 
tine sometimes  descended  for  the  first  time  to  the  bottom 
of  the  scrotum  and  was  strangulated.     Some  years  ago, 
during  one  of  his  terms  of  attendance  at  the  New  York 
Hospital,  a  sailor  was  admitted,  forty  years  of  age,  who, 
while  making  violent  exertion  at  the  capstan,  felt  some- 
thing give  way  in  the  abdominal  walls.     When  admitted 
to  the  hospital  there  was  a  large  swelling  of  the  scrotum 
with  great   tenderness  on    pressure,   constipation,  and 
vomiting.     The  case  was  specially  interesting  because  it 
had  been  seen  by  Dr.  Valentine  Mott,  who  said  he  would 
stake  his  surgical  reputation  that  it  was  not  a  case  of  her- 
nia.    The  shape  was   so  much   like  that  of  a  swollen 
testicle  that  Dr.  Mott   was  disposed   to  disregard   the 
account  given  by  the  patient,  and  supposed  that  instead 
of  straining  himself  he  had  been  struck  by  the  capstan 
bar,  and  that  a  traumatic  orchitis  had  thereby  developed. 
Dr.  Post  had  investigated  the  case  very  thoroughly,  and 
had  made  up  his  mind  that  it  was  one  of  strangulated 
hernia ;  but,  if  he  remembered  rightly,  not  one  of  the 
surgeons  of  the  hospital,  all  of  whom  saw  the  case,  agreed 
with  him.     One  or  two,  however,  expressed  themselves 
doubtful,   while   the  remainder  agreed  with  Dr.  Mott. 
Finally,  consent  was  given  to  an  exploratory  operation, 
when  Dr.  Post  cut  down  upon  a  strangulated  hernia  in  a 
high  state  of  inflammation,  and  the  patient  died  from  ex- 
tension of  the  inflammation  into  the  peritoneal  cavity. 
The  strangulation,  however,  was  relieved.      Since  that 
time  a  number  of  similar  cases  had  occurred  in  the  prac- 
tice of  New  York  surgeons,  but  that  one,  he  believed, 
was  the  first  to  which  attention  had  been  called.     Dr. 
Knight,  of  New  Haven,  had  met  with  a  similar  case. 

With  regard  to  the  general  remarks  made  by  the  author 
of  the  paper,  he  was  disposed  to  agree  with  him,  though 
not  fully  with  regard  to  the  subject  of  taxis.  He  thought 
taxis  was  often  carried  to  an  injurious  extent,  but  he  did 
not  think  it  ought  to  be  passed  over  so  lightly  as  the 
author  of  the  paper  would  seem  to  do,  and  especially  that 
it  should  not  be  passed  over  without  trying  a  change  of 
position.  In  a  case  of  Dr.  Rogers,  in  which  he  had  made 
arrangements  to  operate  before  a  class  of  students,  Dr. 
Post  requested  an  opportunity  to  attempt  to  reduce  the 
hernia  by  a  change  of  the  patient's  position.  He  had  the 
nurse  stand  on  a  bed  and  raise  the  patient's  feet  over  his 
shoulders,  and  in  that  way  the  hernia  was  reduced  and 
the  operation  spoiled.  Dr.  Post  had  succeeded  in  reduc- 
ing the  hernia  in  that  manner  in  a  number  of  instances. 
No  violence  was  thus  done,  but  the  falling  of  the  thoracic 
and  abdominal  contents  toward  the  head  pulled  upon  the 
hernia,  which  proved  safer  and  more  efficient  than  trying 
to  push  it  into  the  abdominal  cavity. 

In  a  case  which  occurred  during  one  of  his  terms  of 


attendance  in  the  New  York  Hospital,  the  patient  had  a 
scrotal  hernia  which  was  somewhat  inflamed  and  very 
tender  upon  pressure.  Before  operating  Dr.  Post  thought 
it  expedient  to  apply  leeches.  Half  a  dozen  leeches 
were  applied  in  the  early  part  of  the  afternoon,  and,  as 
he  had  to  attend  the  funeral  of  a  distinguished  member 
of  the  profession,  he  intended  to  operate  on  his  return, 
but  by  that  time  spontaneous  reduction  had  taken  place, 
produced  by  relaxation  from  local  bleeding.  In  the  main 
he  agreed  with  Dr.  Shrady,  that  a  great  deal  of  harm  was 
done  by  violence  in  taxis ;  but  on  the  whole  iie  should 
think  that  it  were  better  to  make  judicious  attempts  at 
taxis  than  to  proceed  at  once  to  divide  the  stricture. 

With  regard  to  the  operation,  he  believed  that,  as  a 
rule,  a  successful  operation  for  strangulated  hernia  did 
not  prevent  another  descent — that  is,  the  hernia  required 
as  much  support  from  trusses  as  before  the  operation,  and 
sometimes  more,  on  account  of  greater  relaxation  of  the 
ring.  He  thought  it  better  in  all  cases  to  seek  to  pro- 
duce a  radical  cure.  In  an  interesting  paper  published 
by  Mr.  Banks,  of  Liverpool,  the  utility  of  that  practice 
had  been  demonstrated.  The  sac  was  divided  at  its  neck, 
dissected  out,  returned  into  the  abdominal  cavity,  and 
the  ring  was  closed  as  far  as  possible  with  silver-wire 
sutures,  leaving  room  enough  for  the  spermatic  cord.  He 
gave  a  number  of  cases  in  which  no  dangerous  symptoms 
were  caused  by  the  closure  of  the  ring,  and  in  which 
there  was  either  an  absolute  cure  effected,  or  the  size  of 
the  ring  so  much  reduced  that  it  was  possible  to  retain 
the  hernia  in  its  reduced  position  by  a  moderate  amount 
of  pressure.  Mr.  Banks  was  in  the  habit  of  operating  in 
cases  of  hernia  not  strangulated  ;  in  all  cases  in  which  the 
hernia  could  not  be  kept  in  place  by  a  truss.  In  a  cer- 
tain proportion  of  cases  he  effected  a  radical  cure,  and  in 
others  the  hernia  could  be  kept  well  supported  by  a  truss. 
Dr.  Post  agreed  with  Dr.  Shrady  in  the  treatment  of 
the  omentum,  namely,  that  in  all  cases  in  which  it  had 
been  strangulated,  or  had  existed  in  the  sac  for  some 
time,  it  was  better  to  excise  it  than  to  return  it. 

Dr.  McBurney  said  that  Dr.  Shrady  was  to  be  con- 
gratulated on  having  had  so  many  remarkable  successes 
in  a  large  variety  of  strangulated  hemiae.  He  supposed 
the  usual  modem  antiseptic  precautions  were  observed. 

Dr.  Shrady  replied  that  the  wound  was  irrigated  from 
time  to  time  with  the  sublimate  solution,  but  that  the 
spray  was  not  employed.  He  did  not  hesitate  to  expose 
the  gut  to  the  atmosphere,  and  in  two  instances  the  mem- 
bers of  the  house-staff"  were  allowed  to  feel  of  the  stricture 
before  it  was  cut.  In  no  case  did  peritonitis  develop  itself. 
Dr.  McBurney  said  there  was  one  point  in  which  he 
had  been  much  interested,  namely,  the  old  method  still 
used  of  employing  taxis.  Certain  cases  which  had  come 
under  his  observation  had  led  him  to  regret  that  taxis 
was  not  more  generally  acknowledged  to  be  a  dangerous 
as  well  as  a  valuable  procedure  in  cases  of  strangulated 
hernia.  Under  certain  circumstances  it  could  be  used 
with  safety,  but  as  Dr.  Shrady  had  already  pointed  out,  it 
was  capable  of  producing  a  great  deal  of  injury.  It  ought 
to  be  more  commonly  understood  that  some  of  the  so- 
called  methods  of  inducing  the  return  of  the  descended 
hernia  into  the  abdominal  cavity  were  practically  useless, 
and  the  employment  of  such  methods  as  cold,  heat,  or 
even  of  position,  if  it  occupied  much  tinie,  might  prove 
very  serious  for  the  patient  whose  condition  demanded  a 
speedy  operation.  He  thought  it  a  serious  question 
whether  we  had  not  gone  sufficiently  far  with  taxis  when 
we  had  given  ether  and  made  gentle  manipulation  with 
the  fingers  in  attempts  to  reduce  the  hernia. 

Among  a  number  of  other  cases  in  which  taxis  was 
believed  to  have  done  the  patient  harm  were  the  follow- 
ing :  A  few  years  ago  he  saw  a  child  in  consultation  in  a 
neighboring  town,  a  strangulated  hernia  having  existed 
about  twenty-four  hours.  Four  or  five  physicians  were 
present,  two  of  whom  took  the  ground  that  taxis  was  a 
vciy  serious  procedure  in  so  young  a  child.  They  refused 
to  give  their  consent  to  the  administration  of  ether,  and 


6io 


THE  MEDICAL  RECORD. 


[November  29, 1884, 


thought  taxis  was  entirely  unjustifiable  without  it  One 
of  the  others  would  consent  to  taxis  under  ether,  and  the 
fourth  supported  Dr.  McBurney  in  the  recommendation 
of  etherizing  the  patient,  attempting  taxis,  and,  failing,  to 
proceed  to  operate.  The  child  was  not  under  the  influ- 
ence of  the  anaesthetic  a  minute  before  the  hernia  was 
reduced  with  the  slightest  manipulation. 

About  four  years  ago  he  saw  a  case  in  New  Jersey 
which,  as  he  learned  after  his  arrival,  was  under  the 
charge  of  two  homoeopathic  physicians.  The  physicians 
refused  to  allow  anything  whatever  to  be  done,  saying  the 
patient  was  too  old  to  justify  an  attempt  at  taxis,  it  being 
a  case  of  strangulated  hernia,  and  an  operation,  they  said, 
should  not  be  thought  of. 

It  seemed  to  him  it  would  be  very  useful  if  positive  rules 
could  be  given  as  to  the  kind  and  amount  of  taxis  which 
should  be  employed  in  cases  of  strangulated  hernia.  He 
thought  that  the  first  important  point  to  bear  in  mind 
was  that  taxis  should  not  be  attempted  before  etherizing 
the  patient.  By  this  means,  he  thought,  we  entirely 
relaxed  muscular  action  in  the  abdominal  walls  and  re- 
lieved all  tension  upon  the  strangulated  parts,  and  then 
by  inverting  the  patient  the  best  conditions  would  exist 
for  the  return  of  the  hernia.  All  local  applications  were 
intended,  he  believed,  to  reduce  inflammation  and  con- 
gestion of  the  parts,  but  if  it  were  intended  to  try  to 
reduce  the  hernia  by  manipulation  he  thought  the  earlier 
it  could  be  tried  the  better,  and  finding  that  it  failed,  an 
operation  should  be  performed  immediately. 

With  regard  to  the  treatment  of  the  sac,  although  his 
experience  was  slight  he  was  inclined  to  agree  in  the  view 
expressed  by  Dr.  Post  that  the  method  so  largely  practised 
by  English  surgeons  of  late,  of  drawing  together  the  pillars 
of  the  inguinal  canal  by  suture  after  freeing  the  peri- 
toneum, and  thought  it  would  be  likely  to  result  in  per- 
manent cure  in  many  cases. 

Dr.  V.  P.  GiBNEY  had  been  much  interested  in  the 
remarks  made  with  regard  to  taxis.  For  a  number  of 
years  he  had  seen  a  large  number  of  cases  of  hernia,  and 
had  effected  reduction  by  taxis  in  many  cases  at  all  ages, 
and  he  was  not  now  able  to  recall  a  single  instance  in 
which  immediate  or  remote  damaige  had  been  done  by 
taxis  as  he  employed  it.  It  had  been  the  custom  at  the 
Hospital  for  the  Ruptured  and  Crippled  to  first  try  taxis, 
and  that  failing,  to  refer  the  patient  to  the  consulting  staff 
for  operation.  But  taxis  succeeded  in  nearly  all  cases. 
How  nmch  manipulation  in  attempts  to  reduce  the  hernia 
had  been  employed  by  physicians  before  the  patients 
came  to  the  hospital  he  was  unable  to  say,  but  after  their 
admission  he  and  two  assistants  would  try  taxis,  then  give 
ether,  or,  if  the  patient  were  a  child,  chloroform,  and  at- 
tempt reduction  again,  placing  the  patient  in  different 
positions  so  as  to  favor  the  return  of  the  hernial  contents. 
Sometimes  gentle  and  persistent  taxis  would  be  employed 
half  an  hour,  and,  failing,  an  anaesthetic  would  be  admin- 
nistered,  and  usually  the  hernia  would  finally  be  reduced. 
Last  year  a  child  was  brought  to  the  hospital  which  was 
said  to  have  been  suffering  from  a  strangulated  hernia  for 
twenty-four  hours.  There  was  some  vomiting,  a  very 
tense  tumor,  and  marked  signs  of  strangulation.  Dr. 
Gibney  employed  taxis  for  half  an  hour,  then  gave  chlo- 
roform, and  after  another  half-hour's  manipulation  suc- 
ceeded in  getting  the  tumor  about  two-thirds  reduced, 
but  not  being  able  to  produce  any  further  effect,  he  direct- 
ed the  mother  to  take  the  child  home  and  if  the  hernia 
caused  any  further  trouble  to  call  in  a  physician.  She 
returned  the  next  day  and  said  that  in  carrying  the  child 
home  the  hernia  disappeared.  This  was  not  a  solitary 
experience. 

Dr.  Gibney  was  unable  to  understand  how  intelligent 
taxis  was  going  to  do  the  harm  which  it  had  been  claimed 
that  it  would  do.  But  he  agreed  with  Dr.  McBurney,  that 
there  ought  to  be  some  definite  rules  for  the  employment 
of  taxis.  If  after  taxis  had  been  employed  the  surgeon 
should  lose  the  case  by  an  operation,  there  would  be  a 
natural  tendency  to  attribute  the  bad  result  to  the  manip- 


ulations employed  by  the  physician  who  first  saw  the  case. 
He  had  seen  a  number  of  cases  relieved  by  lifting  the 
patient  by  the  hips,  and  other  changes  in  position.  He 
supposed  that  when  an  anaesthetic  was  employed  the  ben- 
eficial  result  was  brought  about  in  the  manner  described 
by  Dr.  McBurney,  both  as  to  the  action  of  ether  and 
chloroform. 

Dr.  John  A .  Wyeth  had  been  surprised  at  the  number 
of  successive  successful  operations  for  strangulated  hernia 
reported  by  Dr.  Shrady,  especially  as  in  many  of  those 
cases  the  condition  had  existed  for  so  long  a  time  as  pre- 
sumably to  debar  a  good  result.  If  he  understood  the 
histories  correctly,  in  a  majority  of  the  cases  strangula- 
tion had  existed  over  twenty-four  hours,  and  in  some  as 
long  as  three  days,  which  was  a  very  long  period  for 
strangulation  to  exist  and  still  permit  of  recovery  after  an 
operation. 

It  had  been  Dr.  Wyeth's  practice  to  operate  early. 
Since  December  20,  1882,  he  had  performed  seven  opera- 
tions for  strangulated  hernia,  all  of  the  patients  recover- 
ing. He  believed  that  the  success  of  the  operations  was 
due  to  the  fact  that  they  were  performed  early  after 
strangulation  had  occurred.  In  some  of  the  cases,  how- 
ever, he  could  wish  to  have  seen  the  patients  sooner. 
He  believed  that  much  of  the  danger  of  the  operative 
procedure  was  due  to  the  previous  improper  use  of  taxis. 
He  regretted  very  much  to  hear  so  eminent  an  authority 
as  Dr.  Gibney  express  himself  so  favorably  toward  taxis, 
thus  encouraging  physicians,  especially  young  men,  to 
place  reliance  upon  this  procedure  in  cases  of  strangulated 
hernia.  He  doubted  whether  there  was  a  surgeon  pres- 
ent who  had  not  met  with  cases  in  which  the  patients  had 
been  brought  near  the  point  of  death  from  prolonged  and 
indiscriminate  use  of  taxis.  No  man  ought  to  touch  a 
strangulated  hernia  until  the  patient  had  been  placed 
under  the  influence  of  ether.  He  himself,  however,  was 
loath  to  try  taxis  even  after  having  anaesthetized  the 
patient.  He  had  never  yet  been  able  to  reduce  a  hernia 
except  by  an  operation.  But  then  he  had  not  pushed 
and  bored  the  gut  back  as  some  would  do.  He  knew  of 
one  case  in  which  the  hernia  had  been  reduced  within 
the  sac,  and  it  was  afterward  necessary  to  operate  to  re- 
lieve strangulation. 

An  operation  for  strangulation  was  as  free  from  dan- 
ger, when  done  under  antiseptic  precautions  and  early 
enough,  as  any  major  operation  could  be.  There  was 
one  precaution  which  he  took  in  performing  the  operation. 
The  inguinal  ring  when  cut  into  acted  as  a  funnel  for 
the  conduction  of  fluids  into  the  peritoneal  cavity,  and  to 
prevent  any  accident  arising  from  this  cause  he  inserted 
his  finger  into  the  ring  and  thus  obliterated  it.  The  gnt 
was  thoroughly  irrigated  with  the  sublimate  solution,  then 
returned,  and  the  finger  placed  on  the  ring  and  retained 
there  until  the  completion  of  the  operation.  Two  strong 
sutures  were  passed  through  the  entire  thickness  of  the 
edges  of  the  wound,  including  the  abdominal  wound  and 
sac  in  one  mass,  and  a  drainage-tube  was  inserted.  He 
thought  Dr.  Shrady  regarded  the  operation  as  being  less 
difficult  than  it  really  was.  Out  of  Dr.  Wyeth's  first  three 
cases  operated  upon  for  strangulated  hernia,  two  of  ^c 
patients  died,  and  it  was  not  improbable  that  the  difficulties 
of  the  operation  and  lack  of  experience  had  something  to 
do  with  the  fatal  issue.  In  femoral  hernia  there  was 
danger  of  injuring  the  obturator  artery  when  derived 
from  the  epigastric  Femoral  hernia  occurred  most 
frequently  in  females,  and  it  was  in  females  that  we  found 
this  artery  in  every  other  case  derived  from  the  epigastric 
branch  of  the  external  iliac.  In  all  of  the  cases  whid 
he  had  found  in  which  death  had  resulted  from  hemor- 
rhage into  the  peritoneal  cavity  from  injury  to  this  vessd, 
the  accident  occurred  in  women. 

In  his  seven  cases  the  strangulation  had  existed  for 
periods  varying  from  two  to  forty-eight  hours.  Whflc 
the  gut  in  one  or  two  instances  was  mottled,  yet  the  cir- 
culation was  restored.  In  one  case  the  condition  of  the 
gut  was  such  that  he  would  have  exsected  a  part,  had  it 


November  29,  1884.] 


THE   MEDICAL  RECORD. 


611 


not  been  that  the  operation  was  performed  by  candle-light 
in  a  tenement  house.     The  patient  recovered. 

Dr.  J.  W.  Wright  said  with  regard  to  taxis,  that  he 
had  always  entertained  the  opinion  expressed  by  some 
of  the  speakers,  that,  as  it  was  generally  employed,  it  was 
a  very  dangerous  procedure  in  strangulated  hernia.     He 
thought,  however,  that  there  was  a  way  to  employ  taxis 
which  was  safe,  or  at  least  by  which  it  was  not  made  a 
very  dangerous  measure.     Taking  hold  of  the  hernial 
tumor  which  was  strangulated,  and  pressing  it  violently 
with  all  the  strength  of  the  hand,  without  using  even  the 
ordinary  and  necessary  skill  to  get  the  hernia  back,  if 
possible,  in  the  inverse  order  to  that  by  which  it  had 
come  out,  was  a  very  dangerous  procedure.     So  im- 
pressed had  he  been  with  this  idea  that  *he  had  come  to 
make  it  a  law  to  himself  never  to  attempt  taxis  in  a 
hernia  which  had  been  strangulated  for  a  long  time,  until 
the  patient  had  been  put  under  the  influence  of  an  anaes- 
thetic, and  then,  if  after  one  reasonable  trial,  not  a  very 
violent  one  at  that,  he  did  not  succeed  in  reducing  the 
hernia,  he  felt  that  the  patient's  chances  of  recovery 
were  infinitely  better  if  he  proceeded  at  once  to  operate. 
With  regard  to  the  reduction  of  strangulated  hernia  by  a 
change  of  position,  alluded  to  by  Professor  Post,  he  con- 
sidered it  a  very  important  point     He  could  recall  two 
or  three  cases  in  which  demise  had  been  strangulated, 
and  two  or  three  attempts  had  been  made  at  taxis  by 
men  who  were  supposed  to  have  the  requisite  skill,  and 
had  failed,  but  the  taxis  had  succeeded  at  the  first  trial 
when  the  patient's  position  was  changed.     In  two  cases 
which  he  recalled  the  reduction  had  been  very  easily  ac- 
complished by  the  operator  standing  with  his  feet  upon 
the  bed,  spreading  the  patient's  limbs,  taking  him  by  the 
knees,  and  lifting  his  body  upon  the  body  of  the  oper- 
ator.    It  was  not  a  very  genteel  position,  especially  if 
the  patient  were  a  female,  but  in  the  male  he  had  known 
it  to  succeed  very  easily.    One  of  these  cases  was  that  of 
an  unrecognized  strangulated  femoral  hernia  which  had 
occurred  in  connection  with  a  double  inguinal  hernia. 
Both  of  the  inguinal  herniae  were  down  at  the  time,  but 
neither  of  them  was  strangulated,  and  yet  the  patient  had 
well-marked  symptoms  of  strangulated  hernia,  and  a  very 
careful  investigation   revealed  the   presence  of  a  very 
small  femoral  hernia  which  was  irreducible  by  taxis  in  the 
recumbent  position,   but  which   was  reduced  by  taxis 
when  the  patient's  hips  were  elevated  in  the  manner  de- 
scribed, and  with  immediate  relief  of  the  symptoms. 

With  regard  to  what  should  be  done  at  the  operation. 
First,  he  did  not  regard  the  operation  for  the  relief  of  a 
strangulated  hernia  a  very  simple  affair,  because  he  felt 
that  every  hernia  was  a  hernia  by  itself,  and  the  details 
of  the  operation  for  any  given  case  could  not  be  learned 
from  books  nor  from  lectures.  Every  hernia  had  certain 
peculiarities  of  its  own.  With  regard  to  the  treatment 
of  the  sac  his  impression  was  that  the  method  described, 
of  dissecting  it  out,  and  stitching  the  walls  through  and 
through,  offered  a  nmch  better  support,  and  a  much 
greater  probability  of  curing  the  hernia  than  the  opera- 
tion which  was  commonly  resorted  to.  That  plan  had 
been  very  clearly  brought  out  by  the  gentleman  to  whom 
Dr.  Post  had  referred,  Dr.  Banks,  of  Liverpool,  who  in 
performing  the  operation  left  the  abdominal  walls  and 
peritoneal  surfaces  as  smooth  as  possible,  so  as  to  guard 
against  the  formation  of  a  new  hernial  pouch. 

Dr-  Post  remarked  that  the  urgency  for  an  early 
operation  was  greater  in  small  than  in  old  or  large  herniae, 
the  reason  for  which  was  apparent. 

Dr.  R.  F.  Weir  agreed  with  most  of  the  speakers, 
that  there  was  considerable  risk  attending  taxis,  but  in 
connection  with  the  question  of  change  of  position  it 
would  often  be  found  that  lateral  motions  would  aid  in  the 
reduction  of  the  hernia.  In  cases  in  which  strangulation 
had  existed  for  some  time  taxis  had  other  risks  than  those 
simply  pertaining  to  manipulation.  The  gut  might  be  in 
such  a  condition  that,  on  being  thus  reduced,  circulation 
would  not  return  and  it  would  give  rise  to  a  fatal  peri- 


tonitis. He  had  become  so  strongly  impressed  with  this 
danger  that  he  had  made  it  a  rule,  when  called  to  see  a  case 
of  strangulated  hernia  which  had  existed  for  some  time, 
not  to  be  satisfied  with  reduction  by  taxis,  but  to  operate 
and  see  what  was  the  condition  of  the  hernial  contents 
before  returning  them  to  the  abdominal  cavity.  It  was 
to  be  taken  for  granted  that  a  sufl5cient  amount  of  taxis 
had  already  been  made  before  the  patient  had  been 
placed  under  the  care  of  the  surgeon. 

He  thought  the  treatment  of  the  wound  adopted  by 
Mr.  Banks,  and  referred  to  this  evening,  was  attended  by 
some  risks,  as  in  one  case  the  patient  died  of  what  the 
house  surgeons  supposed  to  be  peritonitis  resulting  from 
the  operation,  but,  as  the  post-mortem  showed,  death  took 
place  from .  strangulation  of  a  portion  of  gut  in  the  nar- 
rowed ring.  He  believed  other  surgeons  had  had  a  simi- 
lar experience  with  this  method. 

Dr.  Shrady,  in  closing  the  discussion,  said  the  paper 
was  not  intended  to  be  an  exhaustive  one  on  the  subject 
of  hernia.  He  had  been  more  particularly  interested  in 
the  remarks  made  upon  taxis,  and  he  presumed  that  all 
who  had  referred  to  this  point  were  of  one  accord.  He 
thought  it  specially  important  that  taxis  should  not  be 
attempted  seriously  until  after  the  patient  was  under 
ether,  a  point  which  he  had  already  brought  out  in  the 
paper.  That  being  the  case,  no  one  should  attempt 
taxis  unless  he  was  prepared  to  do  herniotomy.  Taxis  was 
tried  in  all  the  cases  reported  in  the  paper  after  the  pa- 
tients were  etherized,  but  unsuccessfully. 

With  reference  to  cutting  off  the  sac  and  securing  it  to 
the  abdominal  ring,  he  had  had  one  unfortunate  experi- 
ence. He  thought  that  the  method  spoken  of  by  Czer- 
ny,  about  five  years  ago,  was  very  promising  from  a 
theoretical  standpoint,  and  he  tried  it  in  one  case  of  ir- 
reducible hernia  in  which  there  was  great  adhesion  of  the 
sac.  He  dissected  out  the  sac,  which  was  one  of  large  size, 
cut  it  off,  secured  the  stump  in  the  external  ring,  and  thought 
he  had  made  a  very  nice  operation  until  peritonitis  de- 
veloped, from  which  the  patient  died.  Since  then  he  had 
not  meddled  with  the  sac  in  that  way,  but  compromised 
by  sewing  as  high  up  in  the  neck  of  the  sac  as  he  could 
by  strong  ligatures,  taking  a  stitch  through  the  pillars  of 
the  ring,  but  leaving  the  sac  in  position.  In  four  cases 
he  was  quite  certain  there  had  been  entire  obliteration 
of  the  sac.  He  had  stated  in  the  paper  that  the  healing  of 
the  wound  by  granulations  was  not  a  disastrous  accident^ 
as  thus  the  sac  would  become  obliterated.  Of  course  a 
little  pouch  would  be  left,  but  by  a  support  the  patient 
would  be  protected  from  further  descent  of  the  hernia. 

The  kind  of  taxis  referred  to  by  Dr.  Gibney  was 
skilled,  and  of  a  different  nature  from  that  usually  prac- 
tised, by  which  the  patient  was  much  harmed  before  he 
came  under  the  care  of  the  surgeon.  He  had  often  suc- 
ceeded in  reducing  the  strangulated  gut  by  taxis,  but 
always  preferred  to  give  ether  before  resorting  to  it.  He 
believed  that  the  method  of  changing  the  position  of  the 
patient  by  suspending  him  by  the  legs,  as  recommended 
by  Dr.  Post,  was  very  often  successful.  Dr.  Shrady 
always  tried  it  in  connection  with  the  other  accepted 
manipulations  before  resorting  to  herniotomy. 

MODIFIED    ELECTRODE. 

Dr.  Beverley  Robinson  presented  a  modification  of 
Dr.  Lincoln's  electrode  for  use  in  the  naso-pharynx. 
The  original  had  a  cup  made  of  ebony,  bone,  or  ivory, 
and  in  his  hands  had  split  and  came  near  entering  the  air^ 
passages  of  the  patient.  He  had  replaced  this  by  a  hard 
rubber  cup,  which,  besides  not  being  likely  to  break,  be- 
came less  rapidly  hot ;  but  it  was  liable  to  take  fire,  and 
also  to  become  soft.  Finally  he  had  substituted  an 
electrode  protected  by  a  layer  of  asbestos,  which  seemed 
to  be  open  to  none  of  the  foregoing  objections.  ' 
general  tuberculosis. 

Dr.  V.  P.  Gibney,  presented  a  specimen  from  a  case 
of  general  tuberculosis,  accompanied  by  the  following 
history  : 


6l2 


THE   MEDICAL   RECORD. 


[November  29,  1884. 


G.  R ,  aged  three  and  a  half  months,  came  under 

observation  one  month  before  death.  Parents  moder- 
ately healthy,  no  history  of  hereditary  tuberculosis  being 
traced.  The  mother  had  had  seven  other  children,  three 
are  living  in  fair  health,  the  others  were  either  still-born 
or  had  died  when  a  few  months  old,  one  with  convulsions, 
the  others  "wasting  away."  The  child  was  a  twin,  the 
brother  having  died  at  the  age  of  seven  weeks.  It  was 
at  birth  of  fair  size,  but  had  never  thrived  after  the  first 
few  weeks,  although  nourished  at  the  breast.  The  bowels 
were  generally  loose,  the  child  having  three  or  four  pass- 
ages a  day.  When  it  was  first  seen  it  was  thin,  but  not 
emaciated.  No  signs  of  inherited  syphilis  were  present. 
Nothing  was  found  in  the  lungs  but  a  few  scattered  r&les. 
There  was  no  vomiting. 

The  case  was  at  first  believed  to  be  one  of  malnutrition, 
but  treatment  was  without  avail.  The  case  grew  steadily 
worse,  and  a  slight  febrile  movement,  somewhat  irregular 
in  its  occurrence,  was  noted.  The  emaciation  finally 
became  extreme.  The  fontanelles  were  depressed ;  there 
was  extreme  nervous  irritability,  but  never  any  convul- 
sions. The  bowels  continued  loose,  and  death  occurred 
from  a  progressive  asthenia.  There  was  slight  tympanites 
noted  at  times.  Cough  existed  for  two  weeks  preceding 
death.  At  the  last  examination  of  the  lungs,  about  ten 
days  before  death,  only  the  signs  of  diffuse  bronchitis 
were  found. 

Brain  was  found  normal.  Right  lung  adherent  through 
nearly  its  whole  extent.  A  small  sacculated  pleurisy  at  its 
lower  anterior  border  containing  about  an  ounce  of  fluid. 
Both  lungs  studded  with  tubercles  on  the  surface,  and 
through  their  substance.  A  small  cavity  about  the  size 
of  a  pea  near  the  root  of  right  lung.  Bronchial  glands 
enlarged  and  cheesy.  Heart  normal.  Liver  studded 
with  tubercles,  as  was  also  the  spleen.  This  was  about 
twice  its  usual  size.  Many  tubercles  found  in  the  great 
omentum,  but  no  lymph  or  pus.  A  few  tubercles  on  the 
surface  of  the  kidneys. 

The  Society  then  adjourned. 


NEW  YORK  ACADEMY  OF  MEDICINE. 
Stated  Meeting,  November  20,  1884. 

FoRDYCE  Barker,  M.D.,    I.L.D.,  President,  in  the 
Chair. 

Dr.  a.  C.  Post  exhibited  a  new  hard-rubber  syringe, 
so  arranged  that  it  could  be  opened  at  both  ends  for  m- 
spection  of  the  pistons,  and  could  be  worked  with  a 
single  hand. 

The  President  introduced  Dr.  W.  C.  Wile,  of  Connec- 
ticut, and  Dr.  M.  F.  Price,  of  San  Francisco,  ex-surgeon 
of  the  United  States  Army,  and  invited  them  to  seats 
upon  the  platform. 

the  surgical  management  of  rachitic  deformities 
OF  the  lower  extremities. 

Dr.  V.  p.  GiBNEY  read  a  paper  on  the  above  subject 
in  which  he  said,  first,  by  the  term  surgical  management 
he  wished  to  convey  the  impression  that  mechanical  ap- 
pliances as  well  as  cutting  instruments  are  surgical  means 
for  effecting  relief. 

With  reference  to  knock-knee,  it  was  not  every  case 
that  demanded  surgical  interference.  Exaggerated  cases 
have  been  known  to  recover  spontaneously. 

Dr.  Gibney  then  referred  to  the  definitions  which  had 
been  given  by  different  authors,  as  Macewen,  of  Glasgow, 
Little,  of  London,  Poore,  of  New  York,  and  others,  and 
asked,  Do  any  cases  of  true  knock-knee  recover  spon- 
taneously ?  It  was  his  opinion  that  a  fair  proportion 
of  the -cases  in  the  United  States  make  a  spontane- 
ous recovery,  and  the  statement  was  based  upon  the  fol- 
lowing reasons  : 

First,  between  the  years  187 1  and  1877,  at  the  Hospital 
for  the  Ruptured  and  Crippled,  he  saw  252  cases  in  chil- 
dren under  fourteen  years  of  age  suffering  with  knock- 


knee.  The  apparatus  employed'  was  theoretically  in- 
operative, practically  it  seemed  to  be  of  some  service. 
In  nearly  all  the  cases  the  limbs  were  restored  to  their 
normal  position.  The  apparatus  employed  consisted  of 
a  pair  of  springs  which  supported  the  limbs,  but  which 
did  not  exert  any  force  against  the  deformity. 

Another  reason  for  the  belief  in  the  spontaneous  cure 
of  knock-knee  was  the  scarcity  of  adult  cases  in  this 
city.  Seldom  does  one  see  adults  with  this  deformity 
walking  on  the  streets  of  New  York.  He  felt  safe  in  as- 
serting that  the  larger  number  of  cases  have  occurred  in 
children  between  three  and  eight  years  of  age,  in  which 
osteotomy  has  been  performed  for  the  correction  of  the 
deformity  of  knock-knee. 

With  regard  to  bow-leg,  he  was  sure  that  many  gen- 
eral practitioners  could  refer  to  children  whose  limbs 
were  bowed  during  early  childhood,  but  which  ultimately 
became  straight.  Of  the  1,005  children  with  this  deform- 
ity seen  at  the  Hospital  for  the  Ruptured  and  Crippled, 
927  were  in  children  under  fourteen  years  of  age.  Only 
three  cases  were  seen  in  adults,  and  only  five  occurred 
between  the  ages  of  fourteen  and  twenty  years.  In  the 
927  patients  the  age  ranged  from  two  to  four  years.  Dr. 
Gibney  believed  that  he  would  be  correct  in  the  state- 
ment that  the  great  majority  •f  the  patients  operated  up- 
on in  this  city  for  bow-legs,  had  been  under  seven  yean 
of  age. 

The  author  of  the  paper  then  discussed  the  following 
questions  :  First,  What  cases  can  be  safely  left  to  nature? 
Of  knock-knee  and  bow-leg  he  would  say  that  children 
under  two  years  of  age  should  not  be  subjected  to  operap 
tion  unless  the  deformity  be  very  exaggerated  ;  also  that 
children  under  three  years  of  age,  with  a  moderate  de- 
gree of  deformity,  could  safely  be  left  to  nature. 

Knock-knee  and  bow-leg  for  the  most  part  are  due  to 
rickets,  and  therefore  considerable  was  to  be  expected 
from  medicinal  measures  toward  effecting  a  cure.  Dr. 
Gibney  then  spoke  of  climatic  influences,  and  the  use  of 
phosphates  of  lime  and  soda  in  the  treatment  of  rickets, 
and  expressed  the  opinion  that  the  latter  were  satisfac- 
tory only  as  they  improved  digestion  and  general  nutri- 
tion. 

In  what  cases  should  manual  force  and  retentive 
splints  be  resorted  to  ?  In  the  first  place,  in  those  pa- 
tients whose  parents  are  unable  to  buy  an  apparatus  or 
too  improvident  to  give  any  attention  to  the  correction 
and  cure  of  the  deformity.  Second,  when  one  has  but 
little  time  to  effect  a  cure.  Third,  where  the  bones  will 
yield  readily  to  such  force,  the  other  conditions  being 
present.  Dr.  Gibney  quoted  upon  this  point  the  con- 
clusions reached  by  Macewen,  that  it  may  be  safely 
concluded  that  brisement  force  has  served  its  time,  and 
cannot  be  practised  in  the  presence  of  the  more  exact 
methods  of  the  present  day.  From  his  own  experience 
and  from  the  drift  of  sentiment,  he  felt  well  assured  that 
Macewen' s  conclusions  would  be  more  strongly  sup- 
ported at  the  close  of  1884  than  they  were  at  the  end  of 
1883  in  the  treatment  of  genu  valgum. 

With  reference  to  apparatus.  Little,  of  London,  was 
an  advocate  of  mechanical  appliances,  while  Macewen,  of 
Glasgow,  was  opposed  to  their  use. 

So  far  as  bow-legs  are  concerned.  Dr.  Gibney  had  been 
guided  in  their  treatment  by  the  principle;  that  if  the 
bones  could  be  sprung  into  position  by  the  use  of  a  moder- 
ate amount  of  force,  a  retentive  apparatus,  consisting  of 
springs,  could  be  applied  with  benefit.  If  the  femur  is 
curved  and  the  inner  condyle  unusually  long  in  a  case  of 
knock-knee,  he  tests  with  his  hands  the  ligaments  of  the 
knee  and  the  femoral  curve,  and  is  guided  by  the  result  in 
his  selection  of  cases  for  apparatus.  The  age  beyond 
which  he  found  this  test  failing  was  four  and  five  years. 

All  springs  now  in  use  are  constructed  upon  one 
principle,  namely,  force  brought  to  bear  against  the  con- 
vexity of  the  curve  at  its  apex.  Dr.  Little,  of  London, 
applies  continuous  pressure  ;  Dr.  Shaffer,  of  New  York, 
employs  momentary  pressure';  Dr.  Poore,  of  New  York, 


November  29)  1884.] 


THE  MEDICAL  RECORD. 


613 


reports  that  about  thirty  per  cent,  of  the  cases  of  genu 
valgum  are  cured  by  mechanical  appliances. 

Osteoclasis. — ^This  operation  has  not  become  popular 
in  this  country,  notwithstanding  its  popularity  in  France. 
Osteotomy, — This  operation  has  become  applicable  to 
nearly  all  rachitic  deformities  of  the  extremities.  For 
the  details  of  the  operation  Dr.  Gibney  referred  to  Dr. 
Macewen's  writings.  He  simply  mentioned  what  Dr. 
Mace  wen  had  stated  at  the  International  Medical  Con- 
gress at  Copenhagen,  that  in  none  of  his  cases  had  death 
occurred  due  to  the  operation.  The  author  of  the  paper 
then  spoke  of  the  accidents  which  might  occur  in  oste- 
otomy, especially  the  hemorrhage.  In  speaking  of  the 
applicability  of  osteotomy  he  made  the  positive  state- 
ment that  he  had  never  seen  an  anterior  tibial  curve 
which  had  been  corrected  by  apparatus  of  any  kind. 

In  nine  linear  osteotomies  and  two  cuneiform  osteoto- 
mies which  he  had  performed  within  the  last  year,  in 
none  of  the  cases  had  the  temperature  of  the  patient 
risen  above  two  degrees  Fahrenheit.  In  one  case  of 
supracondyloid  osteotomy  a  result  occurred  which  he 
believed  to  be  unique — namely,  paralysis  of  the  external 
perineal  nerve,  due  to  injury  by  the  callus. 

From  his  experience  in  the  performance  of  osteotomy 
Dr.  Gibney  had  learned  the  following  lessons : 
First, — Exaggerate  the  correction  of  the  deformity. 
Second. — Examine  the  limb  at  the  end  of  a  week  and 
ascertain  whether  the  amount  of  the  correction  gained  is 
the  amount  desired. 

Third. — Do  not  hesitate  to  refracture  by  manual  force, 
if  necessary. 

Fourth. — With  strict  attention  to  details  in  operating 
and  in  the  use  of  good  plaster-of-Paris  splints,  cases  can 
be  treated  in  dispensaries  nearly  as  well  as  in  hospi- 
tals. 

Fifth. — In  dispensary  cases  do  all  the  operating  you 
propose  at  one  sitting. 

Further,  Dr.  Gibney  remarked  that  he  had  employed 
and  believed  that  Listerism  possessed  advantages,  espe- 
cially with  reference  to  cleanliness.  Support  of  the  limb 
for  three  months  after  the  operation,  by  some  form  of 
splint,  was  not  too  long. 

The  President  invited  Dr.  Joseph  D.  Bryant  to 
open  th^  discussion,  who  said,  with  reference  to  the  cases 
which  can  be  safely  left  to  nature,  that  he  agreed  with 
Dr.  Gibney  entirely  on  the  point  that  in  a  large  number 
of  cases  occurring  in  children  the  patients  would,  if  per- 
mitted to  go  untreated,  ultimately  make  a  complete  re- 
covery. 

The  cases,  however,  which  can  be  safely  left  to  nature 
involved  a  broader  question,  namely,  the  cause  of  bow- 
leg and  knock-knee.  The  exact  cause  of  bow-leg,  it 
was  true,  was  not  yet  thoroughly  determined.  The 
weight  of  the  body  had  been  regarded  as  one  of  the  in- 
fluences, and  probably  had  much  to  do  with  the  produc- 
tion o£  the  deformity.  Muscular  contraction  had  been 
said  to  be  one  of  the  causes,  although  there  was  some 
doubt  on  this  point.  The  position  of  the  child  also,  as 
the  majority  of  these  children  sit  cross-legged,  had  been 
alleged  to  be  one  of  the  causes. 

If  the  weight  of  the  body  in  walking  and  muscular  con- 
traction were  among  the  physical  causes  of  bow-leg,  then 
it  was  true  that  something  could  be  done  to  correct  the 
deformity  or  prevent  its  complete  development,  and  the 
fact  that  many  whom  we  see  upon  our  streets  do  grow 
up  with  bow-legs  gives  rise  to  the  question.  Can  we  safely 
leave  any  of  them  to  nature  ? 

So  far  as  medication  and  hygiene  were  concerned  in 
the  treatment  of  rachitic  deformities,  the  question  was 
probably  well  settled,  and  he  had  nothing  to  add  to  what 
had  already  been  stated  by  the  author  of  the  paper. 

With  reference  to  ♦he  application  of  manuai  force,  the 
rule  which  he  had  adopted  was  this  :  If  in  connection 
with  bow-legs  he  found  that  by  applying  force  he  was 
able  to  spring  the  bones  into  their  normal  position,  he 
had  endeavored  to  rectify  the  deformity  by  making  for- 


cible pressure  upon  the  convexity  of  the  curve  two  or 
three  times  a  week. 

Dr.  Bryant  then  referred  to  a  case  of  exaggerated  an- 
terior curve  of  the  tibia,  which  he  cured  in  this  manner  : 
He  placed  the  patient,  a  boy,  under  the  influence  of  an 
anaesthetic,  then  exerted  as  much  force  as  he  possibly 
could,  without  fracturing  the  bone,  in  the  direction  of  re- 
ducing the  curve,  applied  a  simple  retentive  splint,  re- 
peated this  operation  a  number  of  limes,  and  the  result 
was  a  complete  cure. 

He  regarded  this  method  of  treatment  as  preferable  to 
osteotomy  in  all  cases  of  this  kind,  aside  from  the  fact 
that  in  osteotomy  we  have  a  compound  lesion. 

With  regard  to  apparatus,  he  believed  that  every  case, 
in  which  the  deformity  could  be  corrected  by  manual 
force,  was  a  proper  case  for  the  use  of  some  form  of  re- 
tentive apparatus.  He  was  rather  inclined  lo  favor  the 
use  of  springs  which  should  not  exert  very  much  force, 
only  sufficient  to  correct  the  deformity  without  producing 
any  injury  of  the  soft  parts. 

With  reference  to  osteoclasis,  so  far  as  his  knowledge 
extended,  it  had  been  used  in  this  city  very  little  indeed. 
He  certainly  never  would  resort  to  it  where  pressure  was 
to  be  brought  at  an  angle  involving  the  joint,  as  in  genu- 
valgum.  The  danger  to  the  ligaments  and  to  the  syno- 
vial membrane,  and  the  danger  of  crushing  the  soft  tis- 
sue of  the  head  of  the  tibia,  were  reasons  for  not 
resorting  to  it  in  preference  lo  osteotomy.  However,  in 
marked  tibial  or  femoral  curve,  where  the  force  could  be 
brought  directly  upon  it  without  interfering  with  the 
epiphyseal  junction,  there  might  be  no  very  great  objec- 
tion to  it,  except  in  the  anterior  tibial  curve. 

With  reference  to  osteotomy,  Dr.  Bryant  regarded  it  as 
one  of  the  important  advances  in  surgery  in  the  present 
century,  especially  when  combined  with  antisepsis.  He 
had  not  seen  any  ill  results  in  his  cases  in  Belle vue  Hos- 
pital, and  had  not  seen  a  drop  of  pus  associated  with  his 
operations.  Dr.  Bryant  then  referred  to  an  aggravated 
case  of  antero-lateral  curve  of  the  tibia,  due  to  a  badly 
united  fracture.  He  operated  upon  the  patient  in  Belle- 
vue  Hospital,  and  found  the  bone  so  hard  that  the  chis- 
els were  broken  in  attempting  to  divide  it.  The  wound 
was  dressed  antiseptically,  and  within  eight  months  after 
the  operation  the  patient  went  out  entirely  cured.  He 
referred  to  the  case  merely  as  an  illustration  of  the  bene- 
ficial effects  produced  by  antiseptic  dressings. 

The  oldest  patient  upon  whom  he  had  performed 
osteotomy  was  sixteen  years  of  age.  He  performed  the 
supra-condyloid  operation.  In  that  case  there  was  a  rise 
of  temperature  on  the  third  or  fourth  day,  but  this  quickly 
subsided,  and  no  further  rise  occurred  So  far  he  had 
not  met  with  any 'accidents. 

With  reference  to  the  applicability  of  the  operation,  he 
should  limit  it  to  all  those  cases  where  consolidation  of 
the  bone  has  taken  place.  He  thought  the  general  im- 
portance of  the  subject  was  sufficient  to  engage  the  atten- 
tion of  all  surgeons. 

Dr.  C.  T.  Poore  thought  that  unless  jthe  real  patho- 
logical condition  was  taken  into  consideration  none  of 
these  deformities  could  be  treated  intelligently.  In  one 
class  of  cases  the  deformity  was  not  due  to  bone  lesion. 
When  it  was  due  to  bone  lesion  he  thought  it  was  always 
due  to  rachitis,  leaving  out  traumatic  cases.  If  that  was 
true  the  question  arose.  What  shall  be  the  mode  of  treat- 
ment? In  the  early  stages  of  rachitis  the  bone  can  be 
bent  and  the  deformity  corrected,  but  if  knock-knee  is 
due  to  enlargement  of  the  internal  condyle,  or  bending  of 
the  femur,  etc.,  or  if  the  bones  have  become  hardened, 
they  cannot  be  bent,  and,  therefore,  the  deformity  cannot 
be  corrected  in  this  way. 

He  had  no  personal  knowledge  of  spontaneous  cure 
occurring  in  these  cases  of  deformity  of  true  bony  origin. 
Dr.  Gibney  had  stated  that  he  had  seen  such  cases,  and 
the  statement  was  to  be  accepted  without  question  ;  but 
Dr.  Poore  did  not  think  that  they  were  very  common. 

The  fact  that  we  did  not  see  on  our  streets  many  cases 


6i4 


THE   MEDICAL  RECORD. 


[November  29,  1884. 


jof  knock-knee  in  adults  he  thought  was  due  to  the  fact 
that  there  was  not  so  much  of  rickets  in  this  country  as 
in  some  other  countries. 

He  thought  that  the  deformity  could  be  cured  by 
mechanical  treatment  if  taken  in  time,  and  splints  were 
properly  applied.  However,  if  after  a  time  no  further 
improvement  could  be  secured,  there  was  nothing  further 
to  be  gained  by  the  use  of  splints. 

With  reference  to  the  date  at  which  bones  became  hard, 
each  case  must  be  judged  by  itself.  One  child  may  have 
rachitis  and  recover  with  hard  bone  at  three  or  four  years 
of  age,  while  in  another  case  the  bones  will  not  become 
hard  until  eight  or  nine  years  of  age.  He  regarded  it 
simply  as  a  question  of  nutrition.  After  the  bones  have 
become  hard,  he  thought  that  the  deformity  could  be 
jcorrected  only  by  operation. 

With  regard  to  osteotomy,  he  had  nothing  to  add  to 
what  had  been  said.  In  those  cases  in  which  hemorrhage 
had  occurred,  except  one  in  which  the  femoral  artery 
was  injured  by  a  spicula  of  bone,  the  accident  was  due 
to  causes  which  could  have  been  prevented.  In  his  own 
cases  he  had  not  kept  his  patients  in  bed  more  than  five 
weeks.  He  removed  the  plaster-of-Paris  dressings  at  the 
end  of  four  weeks,  and  probably  the  patient  was  out  of 
bed  within  a  few  days,  and  he  had  not  had  any  recurrence 
of  the  deformity,  nor  did  he  know  of  any  in  which  the 
deformity  recurred  after  the  patients  left  his  charge. 

With  regard  to  osteoclasis,  he  thought  that  it  was  far 
better  than  manual  force,  for  the  fracture  could  be  made 
at  any  point  desired,  provided  that  it  was  done  at  a  suf- 
ficient distance  from  the  malleoli.  He  had  never  pro- 
duced a  fracture  less  than  three  inches  above  the  malleoli, 
and  he  had  never  seen  an  accident  of  any  kind  from  os- 
teoclasis, nor  had  he  ever  failed  to  correct  the  deformity 
by  resorting  to  this  method  of  treatment.  He  had  not 
had  any  experience  in  bending  bones  by  means  of  me- 
chanical appliances. 

With  regard  to  osteotomy  for  bow-legs,  it  seemed  to 
him  that  in  all  cases  of  long  curves  the  osteoclast  could 
be  used  with  advantage ;  the  short  angular  curves  are 
better  treated  by  osteotomy.  In  his  operations  he  had 
not  resorted  to  Listerisra  strictly  speaking,  nor  did  he 
dress  the  wounds  according  to  Mace  wen's  plan. 

Dr.  M.  H.  Henry  had  not,  within  the  last  three  years, 
performed  osteotomy,  but  he  had  seen  the  operation  per- 
formed by  his  friends,  and  he  was  in  perfect  accord  with 
the  statement  which  had  been  made  by  Dr.  Gibney  in 
his  excellent  paper.  For  many  years,  while  in  charge  of 
the  Immigrants'  Hospital,  he  saw  a  large  number  of  chil- 
dren of  foreign  birth.  There  were  no  colored  children, 
and  there  were  but  few  cases  of  deformity  among  the 
Italian  children.  He  mentioned  these  facts  because 
they  served  to  account  for  the  frequency  of  the  disease 
as  it  exists  among  the  children  of  foreign  parents.  The 
.children  were  mainly  rachitic,  and  it  might  be  interest- 
ing to  notice  that  under  the  benefits  of  better  diet  which 
they  received  at  the  hospital,  better  beds,  better  ventila- 
tion, and  clothing,  they  invariably  improved,  and  for  the 
most  part  got  entirely  well.  The  limit  of  their  stay  on 
the  island  was  five  years,  and  it  was  noticed  that  when- 
ever they  were  treated  there  for  more  than  one  year  they 
improved  with  but  little  surgical  interference. 

Dr.  M.  JosiAH  Roberts  remarked  with  reference  to 
the  first  question,  What  cases  can  be  safely  left  to  nature, 
that  the  fact  must  not  be  overlooked  that  the  death-rate 
in  childhood  far  exceeded  that  of  any  other  period  of  life. 
This  was  especially  true  of  those  children  who  were  the  sub- 
jects of  constitutional  disease,  and  therefore  might  explain 
the  scarcity  of  these  deformities  seen  in  adults.  Besides 
this,  recovery  from  the  deformity  was  one  of  degree,  and 
we  must  distinguish  definitely  what  was  meant  by  a  cure, 
when  complete  recovery  was  spoken  of;  and  when  speak- 
ing of  complete  cures,  it  was  necessary  to  ascertain  that 
the  cure  did  not  fall  short  of  the  positive  normal  standard. 
He  would  venture  that  he  could  show  any  gentleman 
vwho  would  walk  with  him  through  the  best  parts  of  the 


city  numerous  cases  of  knock-knees  and  bow-legs  in  slight 
degree,  and  yet  it  would  be  found  that  the  patients  were 
incapable  of  prolonged  locomotion,  or  of  standing  upon 
their  feet  for  long  periods  of  time.  It  did  not  always  re- 
quire, in  a  case  of  knock-knee,  or  in-knee,  a  deformity 
of  more  than  from  two  to  five  degrees  to  cause  very  con- 
siderable inconvenience. 

While  he  agreed  with  the  author  of  the  paper  that 
there  were  cases  which  recovered  spontaneously,  he 
wished  to  impress  the  fact  that  all  the  cases  which  were 
supposed  to  be  cures  were  not  complete  recoveries. 
Dr.  Roberts  then  exhibited  a  series  of  photographs 
illustrating  the  improvement  which  occurs  from  two 
years  of  age  upward  until  fourteen  years  of  age  is  reached, 
when  the  deformity  was  apparently  completely  removed; 
but  the  photographs  showed  that  it  still  remained  to  a 
moderate  degree. 

With  reference  to  the  statement  made  by  the  author 
of  the  paper,  that  in  most  cases  of  bow-legs  the  deformity 
was  due  to  the  continuous  curve  from  the  hips  to  the 
malleoli,  he  wished  to  take  exception.  While  the  de- 
formity appears  to  be  largely  in  the  shaft  of  the  femur  and 
of  the  tibia,  these  were  in  fact  quite  straight,  and  the  de- 
formity was  confined  mainly  to  the  ends  of  the  bones. 
Dr.  Roberts  exhibited  photographs  illustrating  this  point, 
and  made  the  general  statement  that,  in  all  cases  of  de- 
formity we  must  expect  the  deforming  influences  to  mani- 
fest themselves  where  there  is  the  greatest  mobility, 
namely,  at  the  articulations.  Next  in  frequency  are  the 
points  which  are  separated  by  cartilaginous  substance,  as 
the  diaphyses  and  epiphyses.  In  bow-legs  the  principal 
changes  had  taken  place  at  the  articulations  between  the 
epiphyses  and  the  shafts  of  bones. 

With  reference  to  what  cases  can  be  left  to  nature, 
while  he  admitted  that  certain  cases  did  recover,  he  was 
thoroughly  convinced  that  in  every  case  recovery  might 
be  aided  by  surgical  appliances,  and  that  the  patient 
could  get  well  in  a  much  shorter  time  with  surgical  assist- 
ance than  when  left  to  nature. 

With  reference  to  manual  force,  he  agreed  with  Dr. 
Poore,  that  it  is  applicable  only  in  a  limited  number  of 
.cases,  where  the  bones  are  very  soft  indeed.  In  nearly 
all  such  cases  cure  can  be  effected  by  means  of  mechani- 
cal appliances,  and  the  limbs  made  absolutely  straight,  as 
determined  by  goneometric  observations. 

Dr.  Roberts  then  spoke  of  the  necessity  of  using  in- 
struments of  precision  in  determining  the  degree  of  de- 
formity which  is  present. 

With  reference  to  mechanical  appliances,  the  theories 
once  in  use  were  good  in  their  way,  many  of  them  were 
excellent ;  but  he  did  not  think  that  the  ultimatum  had 
yet  been  reached  in  the  application  of  force  for  the  cor- 
rection of  deformities.  He  then  described  at  some  length 
an  apparatus  for  treatment  by  means  of  adhesive  plaster, 
devised  by  the  founder  of  orthopedy  in  this  country,  Dr. 
Davis,  of  New  York.  He  also  spoke  to  considerable 
length  concerning  osteoclasis  and  osteotomy,  and  closed 
with  a  description  of  his  electro-osteotome,  with  which  he 
had  performed  a  large  number  of  osteotomies. 

Dr.  Hopkins  referred  to  a  case  in  which  he  performed 
excision  of  the  joint  for  knock-knee. 

The  President  asked  for  information  with  regard  to 
one  point,  namely,  what  was  the  experience  concerning 
the  influence  of  sex  as  affecting  the  frequency  of  the  dis- 
ease, and  also  as  affiecting  the  frequency  of  spontaneous 
cure.  The  reason  he  asked  was  because  it  had  occurred 
frequently  to  him  to  have  anxious  mothers  express  great 
solicitude  with  regard  to  the  presence  of  bow-legs  or 
knock-knee  in  their  children.  He  had  been  in  the  habit 
of  saying  to  them,  *'  Wait  and  let  us  see  what  the  result 
will  be,"  and  in  most  instances  perfect  recoveries,  so  far 
as  he  had  been  able  to  ascertain,  had  taken  place  before 
adult  life  was  reached. 

Dr.  Gibnev,  in  closing  the  discussion,  remarked  with 
reference  to  the  question  asked  by  the  President,  that  so 
far  as  he  was  able  to  recollect  the  cases  of  bow-leg  and 


November  29,  1884.] 


THE  MEDICAL  RECORD. 


615 


knock-knee  occurred  about  equally  in  the  sexes.  One 
of  the  results  which  he  had  noticed  in  these  cases,  how- 
ever, had  been  what  is  known  as  flat-foot,  and  whenever 
at  the  Hospital  for  the  Ruptured  and  Crippled  he  had 
seen  a  case  of  flat-foot  he  made  further  inquiry,  and  al- 
most invariably  found  that  the  patient  had  during  child- 
hood suffered  from  bow-legs. 

With  reference  to  the  death-rate  among  children,  men- 
tioned by  Dr.  Roberts  as  affecting  the  number  of  cases 
of  deformity  of  the  lower  extremities  seen  in  adults,  he 
would  remark  that  in  Glasgow  it  was  a  notable  fact  that 
bow-legs  and  knock-knees  among  adults  were  very  numer- 
ous, and  therefore  that  the  number  was  probably  not  af- 
fected materially  by  the  death-rate  occurring  in  children 
ID  that  city.  The  cases  of  adults  which  he  had  seen  had 
been  mostly  in  stout  persons,  and  belonged  to  the  form 
which  Dr.  Little,  of  London,  had  termed  atonic  knock- 
knee,  without  the  existence  of  bone  deformity  in  early 
life. 

With  reference  to  the  class  of  cases  referred  to  by  Dr. 
Hopkins,  he  could  only  say  that  his  paper  was  restricted 
to  the  treatment  of  rachitic  deformities. 

The  Academy  then  adjourned. 


OUR  LONDON  LETTER. 

(From  our  Special  Correspondent) 

DISCUSSION  AT  THE  MEDICAL  SOCIETY  OF  LONDON  ON 
"LANCING  children's  GUMS  " — MYXCEDEMA — EFFECT 
OF  EXTIRPATION   OF  THE   THYROID    BODY. 

London,  November  8, 18&4. 

Our  societies  are  all  now  in  full  work.  On  Monday 
last  at  the  oldest  society,  the  entire  evening  was  occu- 
pied with  the  subject  of  lancing  the  gums  in  children. 
This  was  introduced  in  a  racy  statement  of  his  opinions 
by  Mr.  Edmund  Owen,  Surgeon  to  St.  Mary's  Hospital 
and  to  the  Children's  Hospital.  His  first  reason  for 
bringing  it  forward  was,  he  said,  his  slight  practical  ac- 
quaintance with  the  subject,  and  though  he  told  us  that 
he  had  carried  a  gum-lancet  in  his  card-case  for  years, 
he  added  that  he  found  no  work  for  it  upon  infantile 
gums.  This  experience  precisely  agrees  with  my  own. 
In  youth  indeed  I  lanced  many  a  baby's  gums,  it  is  to 
be  hoped  with  benefit ;  but  later  on,  as  fashions  changed, 
I  thought  out  what  ought  to  be  the  reasons  for  doing  so, 
and  resolved  that  I  would  look  for  the  tumefaction  and 
redness  I  had  been  taught  would  certainly  appear  if 
this  necessary  operation  were  delayed,  or  that  I  would 
wait  until  such  evident  obstruction  to  the  eruption  of 
teeth  occurred  as  we  sometimes  see  in  the  case  of  wis- 
dom teeth  in  older  patients.  The  result  has  been  that 
though  I  have  sometimes  assisted  the  emergence  of  an 
adult's  wisdom  tooth,  my  baby-patients  have  escaped 
scot-free.  But  to  return  to  the  discussion,  Mr.  Owen 
said  how  often  do  we  hear  this  remark,  "  My  children  al- 
ways cut  their  teeth  with  diarrhoea  or  a  large  head,"  and 
the  explanation  of  this  he  considered  was  to  be  found  in 
improper  feeding,  an  opinion  which  everyone  who  ob- 
serves the  folly  of  parents  in  this  respect  will  be  ready  to 
endorse.  They  stuff  their  babies'  stomachs  with  food 
which  they  cannot  digest,  and  then  declare  that  the  diar- 
rhoea and  other  disorders  thus  brought  about  are  only 
due  to  teething.  But  surely  teething  is  a  natural  pro- 
cess— not  the  efficient  cause  of  the  many  disorders  to 
which  the  susceptible  infantile  body  is  liable.  No  doubt 
when  a  gum  is  inflamed  scarification  would  ease  it,  but 
when  it  is  not  this  remedy  is  not  indicated.  One  very 
significant  suggestion  was  made  by  Mr.  Owen,  viz.,  to 
keep  a  sharp  lookout  for  essential  paralysis,  which 
comes  on  so  insidiously  at  a  period  when  the  symptoms 
are  likely  to  be  attributed  to  dentition.  In  the  discus- 
sion which  followed  Dr.  Clement  Godson,  Dr.  Braxton 


Hicks,  and  Dr.  C.  J.  Hare,  as  well  as  others,  put  in  a 
plea  for  the  **  good  remedy  out  of  fashion,"  and  Mr.  H. 
Cartwright  threw  in  his  authority  as  a  dentist  in  favor  of 
the  notion. that  diarrhoea  and  convulsions  may  be  caused 
by  dentition.  The  chief  indication  he  assigned  for  the 
operation  was  a  tense  glistening  state  of  the  gum  when 
the  tooth  was  about  to  come  forward,  or  greatly  swollen 
or  inflamed  gums.  Dr.  W.  A.  Duncan  had  seen  the  op- 
eration relieve  diarrhoea  and  convulsions ;  Dr.  Ewart  was 
a  firm  believer  in  the  lancet ;  Dr.  Drew  thought  it  indi- 
cated in  a  febrile  condition  with  pain  in  the  gums  lasting 
for  two  days,  as  well  as  in  some  cases  of  diarrhoea,  bron- 
chitis and  otitis.  Dr.  S.  Taylor  would  use  it  in  a  homy  con- 
dition of  the  gums  ;  and  Dr.  Webb  had  seen  children  on 
the  point  of  death  saved  by  it.  On  the  other  hand.  Dr. 
Travers  had  not  seen  a  single  instance  in  which  he  felt 
justified  in  lancing  the  gums  in  the  last  nineteen  years. 
Mr.  Lowne  said  dentition  was  a  physiological  process 
and  nine  out  of  ten  cases  of  diarrhoea  were  caused  by 
improper  feeding,  and  he  could  not  understand  how  that 
complaint  could  be  brought  about  reflexly  by  dentition. 
Dr.  Sansom  thought  there  was  a  liability  to  use  the  lan- 
cet too  frequently.  Dr.  Hall  thought  it  had  fallen  into 
disuse  since  the  introduction  of  bromides,  and  some 
other  speakers  "  damned  with  faint  praise  "  the  instru- 
ment with  which  most  of  them  had  probably  in  younger 
days  tortured  their  little  patients.  In  reporting  so  fully 
a  discussion  which  some  of  your  readers  may  perhaps 
think  trivial,  it  may  be  ri^ht  to  add  that  this  was  one  of 
the  most  interesting  evenmgs  of  the  session. 

A  case  of  myxoedema  was  brought  forward  at  a  recent 
meeting  of  the  Clinical  Society,  which  was  interesting 
from  a  history  of  its  commencement  in  a  severe  attack  of 
hemorrhage  and  the  continuance  of  a  hemorrhagic  ten- 
dency ;  besides  which  the  patient  suffered  from  oc- 
casional attacks  of  nervous  restlessness,  which  are  not 
only  unusual  but  may  almost  be  thought  to  be  incom- 
patible with  myxoedema.  A  curious  circumstance  may 
also  be  added  respecting  treatment :  the  patient  felt  her- 
self a  good  deal  better  while  under  half-drachm  doses  of 
tincture  of  jaborandi,  and  there  was  at  the  same  time  a 
great  increase  in  the  excretion  of  urea ;  but  no  other  ob- 
jective improvement. 

In  connection  with  the  case  above  mentioned,  attention 
was  once  more  called  to  the  effect  of  extirpation  of  the 
thyroid  gland.  It  will  be  remembered  that  last  year  Dr. 
Kocher,  of  Berne,  reported  that  he  had  observed  after 
this  operation,  in  a  number  of  cases,  the  development 
of  a  cachexia  closely  resembling  the  condition  of  myx- 
oedema; and  a  conjecture  was  ventured  that  this  disease 
might  represent  in  adult  life  the  state  of  cretinism  at  an 
earlier  period.  Be  that  as  it  may,  the  number  of  Kocher's 
cases  was  sufficient  to  show  that  excision  of  the  thyroid 
body  is  in  some  way  related  to  the  strumous  cachexia 
he  had  described,  although  partial  extirpation  was 
followed  by  no  such  condition.  The  notion  first  put 
forward  by  Dr.  Semon,  that  this  state  was  connected  with 
cretinism,  received  some  confirmation  from  a  case  now 
reported  by  Professor  Paul  Bruns.  His  patient,  now 
twenty-eight  years  old,  had  the  thyroid  removed  eighteen 
years  ago.  In  1867,  five  months  after  the  operation,  his 
disposition  had  completely  changed.  From  a  bright,  lively 
child  he  had  become  very  retired  and  quiet,  and  he  now 
is  a  dwarf  and  a  cretin.  After  the  operation  the  develop- 
ment of  the  trunk  and  limbs  had  ceased  and  only  the 
head  had  grown  to  the  size  of  manhood.  The  expression 
is  that  of  an  idiot,  the  skin  and  mucous  membranes  are 
pale.  The  whole  integument  is  dry,  brittle,  and  thick- 
ened by  a  peculiar  soft  gelatinous  infiltration.  There  is 
also  swelling  of  the  tongue,  palate,  and  tonsils,  giving  rise 
to  slow,  difficult  speech.  Sensibility  and  muscular  power 
preserved,  but  the  patient  cannot  work,  can  hardly  walk 
fifty  steps.  His  mental  faculties  are  less  developed  than 
those  of  a  boy  of  ten.  This  important  case  seems  to 
furnish  us  with  a  blending  of  myxoedema  and  cretinism, 
and  it  was  suggested  that  both  conditions  are  due  to  the 


6i6 


THE   MEDICAL  RECORD. 


[November  29,  1884. 


loss  of  the  thyroid  gland.  Certainly  some  of  the  other 
facts  recorded  point  in  the  same  direction,  but  they  seem 
at  present  scarcely  sufficient  to  establish  so  large  a  gen- 
eralization, and  in  this  case  it  would  be  easy  to  suggest 
another  explanation. 

Official  List  cf  Changes  in  thi  StaHans  and  DuHes  of  Offices 
servinfT  in  thi  Medical  Departnunt^  United  States  Army, 
from  November  \(ito  November  22,  1884. 

McKee,  James  C,  Major  and  Surgeon.  Leave  of 
absence  extended  one  month.  S.  O.  273,  A.  G.  O., 
November  20,  1884. 

GoDDARD,  C.  E.,  Major  and  Surgeon.  Assigned  to 
duty  at  Fort  Yates,  D.  T.  S.  O.  138,  Department  of 
Dakota,  November  15,  1884. 

Cowdrey,  S.  G.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month.  S.  O.  237, 
Department  of  the  East,  November  17,  1884. 

Havard,  Valery,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  four  months,  with  permis- 
sion to  go  beyond  sea,  to  take  effect  when  his  services 
can  be  dispensed  with  at  his  present  station.  S.  O.  268, 
A.  G.  O.,  November  14,  1884. 

Taylor,  A.  VV.,  First  Lieutenant  and  Assistant  Sur- 
geon. Relieved  from  duty  at  Fort  Omaha,  Neb.,  and 
ordered  for  duty  at  Fort  D.  A.  Russell,  Wyo.  T.  S.  O. 
1 01,  Department  of  the  Platte,  November  19,  1884. 

Phillips,  John  L.,  First  Lieutenant  and  Assistant 
Surgeon.  Assigned  to  duty  at  Fort  Keogh,  M.  T. 
S.  O.  134,  Department  of  Dakota,  November  5,  1884. 


%t\xs  Instruments^ 


A  RAPID  METHOD  OF  CONTINUOUS  SUTURE. 
By  p.  J.  PRENDERGAST,  M.D., 

BROOKLYN,   M.   Y. 

After  having  used  the  needle  of  Dr.  Wackerhagen 
with  great  satisfaction  for  interrupted  suture,  I  have 
found  that  it  can  also  be  used  for  the  continuous  suture, 
and  that  by  a  very  rapid  method,  without  utilizing  the 
eye  in  the  blunt  end.     The  plan  is  as  follows,  viz. : 

The  thread  having  been  passed  under  the  bridge  of 
the   needle,    each   portion   being   of  equal  length,  the 


needle-holder  is  applied ;  the  needle  is  then  passed 
through  the  tissues  and  a  loop  of  thread  is  drawn  out, 
a  piece  of  large  size  catgut  is  now  passed  through  the 
loops  by  an  assistant,  each  time  the  needle  is  withdrawn. 
By  this  process  we  possess  a  double  advantage — non- 
disturbance  of  the  needle-holder,  and  one  threading  of 
needle  for  ordinary  cases.  I  doubt  not  this  needle  will 
henceforth  be  used  as  frequently  and  satisfactorily  for 
the  continuous  as  for  the  interrupted  suture. 


A   NEW   ELECTRIC   OTOSCOPE. 
By  ROSWELL  PARK,  M.D., 

BUFFALO,  N.  Y. 

To  those  who  have  a  means  of  supplying  by  some 
form  of  battery  in  their  office  an  electric  current  of  suf. 
ficient  power,  this  little  instrument  will  commend  itself 
as  a  most  convenient  demonstrating  otoscope,  and  one 
by  which  searching  examinations  can  be  made  irrespec- 
tive of  time  of  day  or  light. 

It  consists  of  an  otoscope  of  conventional  pattern, 
much  like  Brunton's  or  Hasenstein's,  from  which  the  or. 
dinary  flaring,  funnel-like  side  tube  for  collecting  the 
rays  of  artificial  light  has  been  removed,  and  in  its  place 
a  thimble  inserted  within  which  is  the  platinum  coil  made 
white  hot  by  the  passage  of  the  current.  The  battery 
wires  are  connected  with  a  perforated  flange  on  either 
side  the  thimble,  and  a  little  knob  to  be  pressed  down 
by  a  finger  of  the  hand  which  holds  the  instrument  makes 
the  connection  in  its  interior,  so  that  the  light  islfunder 
perfect  control.     Back  of  the  coil  is  a  dead  white  mirror 


surface  which  serves  to  economize  and  intensify  the  light 
The  portion  of  the  instrument  corresponding  to  the  ear- 
speculum  proper  is  made  in  three  sizes,  and  of  polished 
metal,  or  of  hard  rubber,  as  may  be  desired.  The  thim- 
ble fits  easily  in  its  socket,  and  is  turned  half  round  as 
the  instrument  is  changed  from  one  ear  to  the  other,  so 
that  the  knob  may,  if  desired,  always  have  the  same  rel- 
ative position.  And  when  sunlight  or  artificial  light 
from  a  lamp  are  wanted  the  thimble  is  entirely  removed 
and  the  funnel -tube  inserted.  The  battery  used  may  be 
one  of  the  little  storage  batteries  accompanying  Trouv^s 
"  polyscope,"  a  cautery  battery,  or  any  other  supplying 
sufficient  intensity. 

MARCONI'S  TONSILLITOME. 

In  this  instrument  the  Mackenzie  blade  is  combined 
with  Matthews'  fork  and  handle,  each  of  which  are  the 


superior  features  in  the  respective  instruments.  The 
advantages  of  this  instrument  will  readily  appear  to  those 
within  whose  specialty  of  practice  it  falls. 


A  DENTIST  at  Triangle,  N.  Y.,  once  received  an  order 
for  a  block  of  teeth,  as  follows  :  **  My  mouth  is  3  inches 
acrost,  %  inches  through  the  jaw  ;  sum  humocky  on  the 
edge ;  shaped  like  a  horse-shoe,  toe  forward.  If  you 
want  me  to  be  more  particklar  I  shel  hav  to  cum  thar. 
Yours  truly, ." 


The   Medical   Re 


A   Weekly  yournal  of  Medicine  and  Surgery 


oiTY  r/osj 


VoL  a6,  No.  23 


New  York,  December  6,  1884 


Whole  No.  735 


©rigtimX  ^vticUe. 


CONCUSSION  OF  THE  SPINE  AND  ITS  RELA- 

TION  TO  NEURASTHENIA  AND  HYSTERIA.' 

By  C.  L.  DANA,  A.M.,  M.D., 

PROFESSOR  OF  NBKVOUS  AND  MBNTAL  DISEASBS  IN  THB  NRW  YORK  F05T-GRADUATB 
MBOICAL  SCHOOL. 

The  physician  who  is  called  into  court  to  testify  in  a  case 
of  spinal  injury  witnesses  a  curious  spectacle.  The  law- 
yer for  the  prosecution  waves  before  the  jury  a  volume 
of**Erichscn  upon  Spinal  Concussion."  He  reads  to 
them,  in  impressive  accents,  the  statement  that  every  in- 
jury to  the  spine,  however  slight,  is  full  of  danger  to  the 
sufferer.  He  asks,  with  sonorous  emphasis,  if  Mr.  Erich- 
sen  is  not  a  surgeon  of  world-wide  fame  ;  and  if  he  does 
not  say  that  slight  injuries  to  the  back  may  cause  chronic 
spinal  disease  of  the  most  serious  character.  He  sneers 
at  the  work  of  a  certain  Mr.  Page,  who  is  known  to  be 
professedly  only  a  railway  surgeon.  He  shows  that  his 
client  has  paralysis,  anaemia,  meningitis,  in  fine,  "  spinal 
concussion." 

On  the  other  hand,  the  lawyer  for  the  defence  bran- 
dishes triumphantly  a  larger  work,  by  Mr.  Herbert  Page, 
on  "Injuries  to  the  Spine ;" "he  reads  to  the  jury  cases  of 
malingering  therein  related,  shows  that  Mr.  Erichsen  has 
for  years  made  a  business  of  being  an  expert  for  people 
with  injured  spines,  but  that  he  has  never  yet  found  a 
case  that  proved  fatal.  He  quotes  Mr.  Page's  two  hun- 
dred and  thirty-four  cases  of  spinal  concussion,  in  most 
of  which  recovery  resulted,  and  shows,  through  his  medi- 
cal expert,  that  the  spinal  cord  is  so  admirably  protected 
that  it  could  never  possibly  be  injured  by  anything  so  ut- 
terly trivial  as  a  railway  collision. 

The  medical  experts  themselves  in  these  cases  neces- 
sarily testify  in  the  most  diverse  way,  according  to  their 
natural  bias  or  the  particular  surgical  authority  or  pecu- 
niary support  upon  which  they  rely.  And  authorities  are 
so  unsettled  and  contradictory,  and  symptomatological 
data  so  uncertain,  that  two  medical  men  can  with  perfect 
honesty,  if  they  go  by  written  works,  support  quite  oppo- 
site views. 

It  is  on  account  of  the  existence  of  this  uncertain  state 
of  written  medical  opinion  that  I  venture  to  present  the 
subject  of  spinal  concussion  now.  I  do  not  so  much  wish 
to  offer  any  original  views  of  my  own,  or  detail  my  per- 
sonal experience  (which  has  been  sufficient  to  show  me 
in  how  unsatisfactory  a  state  the  subject  of  spinal  concus- 
sion is),  but  rather  to  lay  down  the  mooted  questions 
regarding  injuries  to  the  spine  and  their  sequelae,  to 
present  what  is  in  my  opinion  the  just  and  proper  view  to 
take  of  them,  and  to  ask  for  corroboration  or  criticism 
of  my  audience  to-night. 

Under  the  term  concussion  of  the  spine  Mr.  Erichsen 
includes  four.different  conditions  : 

First, — Concussion  of  the  spinal  cord  itself.    Here  ajar 

*  Read  at  a  meetinc  of  the  New  York  Neurological  Society,  November  xi,  1884. 
According  to  Poor  (Railroad  Manual.  1883),  there  are  389,190,783  passengers 
carried  upon  the  113,329  miles  of  road  in  the  United  Sutes  yearly  (in  1882).  This 
IS  about  six  times  the  total  population.  For  the  Middle  States  the  number  of 
passengers  is  ten  per  cent,  of  the  population,  and  for  New  York  about  fifty 
milliOD.  Among  these  fifty  million  there  occurred  in  1882-83,  according  to  the 
Kteort  of  the  New  York  Railway  Commissioners,  40  deaths  and  194  injuries.  In 
addition  to  this  there  occurred  to  employes  175  deaths  and  732  injuries,  and  to  all 
others  280  deaths  and  250  injuries,  making  the  total  casualty  returns  in  this  State 
for  one  year  495  deaths  and  1,166  mjuries.  Calculating  upon  this  basis,  the  num- 
wr  of  deaths  annually  among  railway  passengers  would  be  about  232,  the  number 
otuijuries  1,125.  For  the  whole  country  the  total  number  of  deaths  Mrould  be  not 
ar  trora  2,871  among  passengers,  employes,  and  others,  while  the  total  number 
ofinjunes  would  be  about  6,763. 


or  shake  of  the  cord  disorders  or  suspends  its  functions 
without  causing  any  detectable  lesion. 

Second. — Spmal  hemorrhage  and  compression. 

Third. — ^Acute  and  subacute  inflammation  of  meninges 
and  cord. 

Fourth. — Chronic  meningitis  and  myelitis,  consequent 
upon  simple  concussions  of  the  cord,  apoplexies,  or  acute 
or  subacute  inflammations. 

He  describes  as  accompanying  or  following  these  in- 
juries symptoms  attributed  to  general  nervous  shock. 
These  symptoms  are  those  of  cerebral  irritability  and 
asthenia,  spinal  anaemia  and  irritation,  and  a  long  series 
of  visual  troubles.  Without  going  into  any  analysis  I 
think  I  can  say  from  a  careful  reading  of  his  book  that 
Mr.  Erichsen' s  teachings  and  their  implications  are  some- 
what as  follows : 

That  there  is  such  a  thing  as  concussion  of  the  spina! 
cord,  pure  and  simple,  whereby  the  functions  of  the  cord 
are  temporarily  suspended. 

That  such  a  concussion  of  the  cord  may  be  followed 
by  recovery  (and  generally  is),  or  by  death  or  chronic 
disease. 

That  there  is  such  a  thing  as  concussion  of  the  spine, 
wherein  the  whole  vertebral  column,  with  its  envelopes 
and  contents,  is  jarred  or  injured  in  various  ways. 

That  this  term,  "  concussion  of  the  spine,"  is  one  of  the 
widest  inclusiveness,  taking  in  symptoms  of  injury  to  the 
cord,  of  injury  to  the  vertebral  column  and  muscles,  and 
of  general  nervous  shock  and  its  sequelae. 

That  an  injury  to  the  spine  or  body  may  prove  most 
serious  (to  the  spine  especially),  and  that  even  trivial  in- 
juries may  cause  grave  organic  disease  of  the  cord  or  its 
membranes. 

That  spinal  anaemia,  spinal  irritation,  hysteria,  and  allied 
troubles  may  result  from  slight  injuries  to  the  spine,  and* 
the  nervous  shock  of  the  accidents  causing  them. 

That  these  last-mentioned  symptoms,  as  well  as  those 
of  a  supposed  chronic  meningo-myelitis,  may  develop 
later,  and  slowly,  after  a  period  of  comparative  health, 
and  that  they  are  very  serious  in  character. 

That  malingering  occurs  and  should  be  looked  out  for. 

That  serious  visual  troubles  occur. 

I  might  add  here  that  Mr.  Erichsen  reports  in  support 
of  these  views  thirty-one  cases  in  detail,  of  which  nine 
were  the  result  of  railway  accidents. 

Turning  now  to  Mr.  Page's  work,  already  referred  to, 
it  should  be  said  in  the  beginning  that  it  is  by  no  means 
an  aggressive  criticism  of  Erichsen  alone.  The  writer 
endeavors  to  produce  a  systematic  treatise,  and  although 
he.  puts  his  arguments  together  badly,  he  has  succeeded  in 
making  an  original  and  valuable  contribution  to  the  sub- 
ject in  hand.  It  is  true,  however,  that  much  space  is  de- 
voted to  pulling  down  some  of  the  pathological  creations 
of  the  London  Hospital  surgeon's  fancy.  Without  at- 
tempting at  all  to  analyze  his  book,  I  propose  to  set  off 
the  synopsis  given  of  Mr.  Erichsen's  teachings  by  certain 
propositions,  which  I  believe  to  embody  the  opinions  of 
Mr.  Page,  and  then  to  enumerate  the  mooted  points 
between  them.  The  views  of  Mr.  Page,  so  far  as  I  under- 
stand him,  are  : 

That  the  existence  of  such  a  thing  as  concussion  of  the 
spinal  cord,  pure  and  simple,  is  unproven  and  extremely 
doubtful. 

That  the  .spinal  cord  cannot  be  directly  contused  or 
injured  by  shakes,  blows,  or  violence  to  the  body  unless 
there  is  a  fracture  or  dislocation  of  the  spinal  column. 


6i8 


THE  MEDICAL  RECORD. 


[December  6,  1884. 


That  so-called  cases  of  concussion  of  the  cord,  fol- 
lowed by  softening  and  death,  or  by  symptoms  of  myeli- 
tis, are  cases  of  spinal  apoplexy,  or  of  ^dislocation  or 
fracture  with  compression. 

That  the  term  concussion  of  the  spine  is  arbitrary, 
vague,  and  misleading. 

That  injuries  to  the  spine  very  rarely,  if  ever,  produce 
chronic  non-fatal  forms  of  meningitis,  myelitis,  or  menin- 
go-myelitis,  so  called ;  but  that  the  symptoms  attributed 
to  these  conditions  are  the  result  of  lumbago,  strains, 
and  ruptures  of  muscle  and  ligaments,  injury  to  periph- 
eral nerves,  and  general  nervous  shock,  setting  up  neu- 
rasthenic and  neuromimetic  disorders. 

That  these  neurasthenic  and  neuromimetic  disorders, 
though  often  serious,  are  not  fatal,  but  tend  toward  re- 
covery ;  and  that  the  patient  and  the  litigation  are  often 
responsible  for  many  of  them. 

That  the  symptoms  being  mostly'subjective,  it  is  diffi- 
cult to  exclude  deception  ;  that  some  unconscious  de- 
ception often  occurs,  even  with  honest  patients. 

That  no  serious  visual  troubles  follow  in  these  chronic 
functional  disorders. 

The  general  tenor  of  Mr.  Page's  work  is  to  the  effect 
that  the  spinal  cord  is  a  very  carefully  protected  and  not 
easily  injured  organ.  From  a  comparison  of  these  views 
with  those  of  Mr.  Erichsen,  we  may  learn  what  are  the 
disputed  points  regarding  the  effects  of  injuries  to  the 
spine. 

Put  in  the  form  of  queries,  they  are  as  follows  : 

First, — Whether  external  violence  can  cause  a  simple 
concussion,  and  perhaps  contusion  of  the  cord,  of  a  char- 
acter analogous  to  concussion  of  the  brain,  or  whether 
the  cases  heretofore  so  considered  are  really  examples  of 
spinal  hemorrhage,  or  of  dislocation,  separation,  or  fract- 
ure with  compression  ? 

Second. — Whether  external  violence  or  jars  can  cause 
direct  contusion  of  the  cord,  or  produce  a  structural 
change  that  ends  in  softening,  there  being  no  lesion  of  the 
enveloping  osseo-ligamentous  parts  ? 

Third, — Whether  blows  or  jars,  ever  or  often,  set  up 
a  chronic  meningo -myelitis  or  myelitis,  no  lesion  of  the 
spinal  column  being  present  ? 

It  is  to  this  last  category  that  Mr.  Erichsen  relegates  a 
large  portion  of  his  reported  non-fatal  cases  of  concussion 
of  the  spine,  and  we  may  put  in  here,  therefore,  the 
counter-query : 

Whether  in  a  very  large  number  of  cases  of  chronic 
nervous  disturbance,  following  railway  and  other  acci- 
dents, cases  usually  diagnosticated  in  a  routine  way  as 
"  concussion  of  the  spine,"  or  chronic  meningo-myelitis, 
the  disease  is  not  really  mental  (neurasthenia,  hysteria, 
hypochondriasis),  or  else  partly  mental  and  partly  the 
result  of  injuries  to  the  spinal  muscles,  ligaments,  and 
nerves  ? 

Fourth, — Finally,  the  question  is  raised,  Whether 
serious  organic  visual  troubles  result  from  railway  and 
other  accidents  in  which  the  spine  or  body  is  injured,  but 
not  the  eye  directly? 

Some  of  the  foregoing  queries  have  plainly  a  more 
scientific  than  practical  interest.  As  to  the  first  one,  for 
example,  that  of  the  existence  of  a  concussion  of  the 
spinal  cord,  pure  and  simple.  We  know  that  after  violent 
blows  or  falls  persons  suffer  from  a  temporary  paraplegia. 
^yhether  this  is  due  to  a  molecular  disturbance  of  the 
tissue  of  the  cord  or  to  a  spinal  hemorrhage,  the  clini- 
cal facts  are  the  same.  But  I  believe  that  there  is 
enough  evidence  to  justify  one  in  retaining  the  term 
^*  concussion  of  the  cord,"  a  term  sanctioned  by  ancient 
authority  and  adopted  by  every  surgical  writer. 

The  evidence/r^  and  con^  collected  by  Erichsen,  Page, 
and  myself,  is  the  following  :  Erb  cites  a  case  which  he 
iDelieves  illustrates  spinal  concussion  (**  Ziemssen*s  Cyclo- 
paedia of  Medicine,"  Art.,  Concussion  of  Spine),  and 
.guardedly  admits  its  existence.' 

'  Se«  bibliography. 


Le  Gros  Clark  also  (op.  citj  thinks  that  the  term 
concussion  of  the  spinal  cord,  used  analogously  to  concus- 
sion of  the  brain,  is  justifiable.  He  relates  two  cases  appar- 
ently illustrating  this,  but  admits  later  that  there  might 
be  some  organic  lesion. 

Shaw  (op.  cit.)  cites  a  case  where  there  was  apparently 
simple  concussion,  but  the  patient  died  and  the  autopsy 
showed  a  hemorrhage  in  cord. 

Dr.  Abercrombie  (op.  cit.^  relates  the  history  of  a  case 
where  a  man  was  struck  in  the  back  with  a  rock  and 
rendered  paraplegic  for  several  weeks  ;  he  ultimately  re- 
covered. Abercrombie's  opinion,  that  there  is  a  tnie 
simple  concussion  of  the  cord,  is  apparently  based  on 
this  case,  and  on  those  of  Boyer  and  Frank,  to  which 
authorities  he  refers. 

Dr.  T.  Buzzard  {TheLancety  867,  vol.  i.,  pp.  389,  435, 
509,  623)  quotes  a  number  of  cases  believed  to  illustrate 
concussion  of  the  cord,  taken  from  Dr.  J.  L.  Caspci's 
**  Ueber  des  Verletzungen  des  Ruckenmarkes,"  1823,  Ber. 
lin.  This  author  gives  Frank's  cases  reported  in  his 
**  Kleine  Schriften,"  also  one  by  Valsalva  and  other  old 
authors. 

Boyer  (op.  cit,  p.  135)  relates  two  cases.  In  one  the 
patient  was  struck  on  the  back,  in  the  other  he  strained 
his  back  in  a  violent  muscular  exercise.  Both  became 
suddenly  paraplegic,  died  in  a  few  weeks,  and  upon  au- 
topsy  no  lesion  of  the  cord  was  discoverable. 

These  cases  are  not  conclusive,  because  no  microscopi- 
cal examination  was  made.  In  the  second  case  there 
could  not  have  possibly  been  any  concussion^  as  the  man 
was  simply  going  through  a  difficult  muscular  exercise  for 
the  amusement  of  his  friends. 

Mayo  (op.  cit.)  expresses  the  opinion  that  concussion 
of  the  spinal  cord  may  cause  complete  suspension  of  its 
functions.  His  illustrative  cases  may  be  explamed  on 
the  theory  of  a  hemorrhage. 

Syme  ("  Principles  of  Surgery,"  Third  Edition,  p.  433) 
states  that  the  cord  may  have  its  functions  suspended  by 
a  concussion,  as  does  the  brain.  He  states,  however, 
that  an  efifusion  of  blood  or  serum  probably  complicates 
these  cases. 

Dr.  John  A.  Lidell  {American  Journal  of  the  Medical 
Sciences^  vol.  xlviii.,  p.  305)  expresses  his  belief  in  simple 
spinal  cord  concussion,  and  relates  three  cases  illustrating 
it,  as  he  believes.  The  paraplegia  in  these  cases  could 
be  explained,  however,  by  the  injury  to  peripheral  nerves 
or  by  hemorrhage. 

Dr.  S.  Wilks  (**  Diseases  of  the  Nervous  System,"  p.  201) 
states  that  he  has  more  than  once  seen  a  man  receive  a 
severe  injury  to  the  back,  become  paralyzed,  and  recover 
in  a  few  days.  Here  he  thinks  the  cord  is  stunned. 
He  reports  the  case  of  a  porter  who  received  a  severe 
blow  on  the  head  (?)  and  back.  He  was  stunned  for  a 
time,  but  resumed  work  for  three  days,  then  developed 
paraplegia  and  died.  Autopsy  showed  only  a  very  slight 
granular  and  fatty  change  in  the  cord. 

G.  Fisher  {Deut,  Zeitsch.  Chir,)  cites  the  case  of  a 
man,  aged  twenty-one,  who  fell,  striking  on  his  back. 
There  was  complete  paralysis  of  the  extremities,  trunk, 
and  spinal  centres.  Death  occurred.  Post-mortem 
showed  only  a  slight  meningeal  effusion.  Paralysis  was 
referred  to  shock. 

I  have  taken  the  trouble  to  bring  these  cases  together, 
adding  a  number  not  quoted  by  Erichsen  or  Page,  because 
in  the  works  of  those  authors  the  clinical  and  patho- 
logical evidence  is  not  systematically  arranged,  and  it  is 
by  no  means  easy  in  reading  Mr.  Page's  book  to  follow 
his  arguments  and  his  evidence. 

I.  These  cases  may  not  of  themselves  positively  prove 
the  existence  of  a  concussion  of  the  cord.  In  view  of  the 
facts  presented  under  the  second  query,  however,  show- 
ing that  shakes  and  injuries  can  cause  a  softening  of  the 
cord,  the  certainty  that  it,  in  rare  cases,  can  be  "  con- 
cussed," so  as  to  suspend  its  functions,  becomes  very 
great. 

II.  As  to  whether  jars  and  injuries  to  the  spine  can 


December  6,  1884.] 


THE  MEDICAL  RECORD. 


619 


cause  direct  structural  change  leading  to  softening  of  the 
cord,  there  being  no  lesion  of  the  spinal  column — 

Sir  Benjamin  Brodie  (op.  cit.)  first  laid  down  the  view 
that  such  a  thing  was  possible.  And  though  it  is  true 
that  he  cites  no  illustrative  cases,  yet  he  writes  with  a 
particularity  which  leads  one  to  believe  that  he  has  seen 
such  cases.  As  slightly  confirmatory  of  this  view  also,  Gull 
("Gu/s  Hospital  Reports,"  Series  iii.,  191,  1858,  Case 
xxiii.)  reports  the  case  of  a  porter,  who  received  a  severe 
blow  directly  upon  the  cervical  spine.  There  was 
paralysis  of  motion  in  the  left  arm,  and  of  motion  and 
sensation  in  legs.  Post  mortem  showed  softening,  with  a 
slight  ecchymosis  in  gray  matter,  and  contusion  of  cord 
opposite  fourth  and  fifth  cervical  vertebrae.  The  spine 
was  normal,  except  for  a  separation  of  the  bodies  of  the 
fourth  and  fifth  cervical  vertebrae. 

TA^  Lancet  (April  19,  1877,  P-  S7i)  contains  the  re- 
port of  the  case  of  a  Mr.  John  Jepson,  who  was  bruised 
and  shaken  in  a  collision.  He  attended  to  his  business 
for  a  fortnight  Symptoms  of  spinal  concussion  then  set 
in :  spinal  tenderness,  muscular  twitchings,  paraplegia, 
mental  symptoms.  In  six  months  he  died  of  pneumonia. 
Post-mortem  showed  considerable  softening  in  the  dorsal 
portion  of  the  cord. 

Mr.  Curling  ("Transactions  of  Pathological  Society," 
vol.  viii.)  records  the  case  of  a  boy,  aged  eight,  who  fell, 
striking  on  the  buttocks,  became  paraplegic,  and  died  in 
three  months  and  a  half.  Postmortem  showed  cord 
softened  in  several  places. 

Dr.  Lochner,  of  Schwalbach  (Aerttliches  Intelligenz- 
hlait,  October  19,  1875),  reports  two  cases  of  softening 
of  the  cord  following  a  blow  or  fall,  no  lesion  of  the  spinal 
column  being  found.  Dr.  Abercrombie  also  cites  a  similar 
case  (op.  cit,  p.  343). 

III.  As  to  whether  injuries  to  the  spine,  shakes,  and 
jars  can  cause  a  subacute  or  chronic  myelitis  or  meningo- 
myelitis,  the  spinal  column  not  being  injured.  Un- 
doubtedly some  such  cases  do  exist  In  judging  of  this 
question,  however,  it  is  well  to  bear  in  mind  that  chronic 
myelitis  and  meningitis  are  serious,  and  eventually  fatal, 
diseases.  Therefore,  if  railway  and  other  accidents  pro- 
duced them,  pathologists  would  see  them. 

Mr.  Page  collects  the  histories  of  only  two.  One  was 
reported  by  Mr.  Hutchinson  [Medical  Times  and  Gazettty 
1879,  ^o^-  ^'s  P-  34^)*  ^^  ^^  ^  ^^^  ^^  paraplegia  from 
myelitis  following  injury  to  the  back.  The  patient  re- 
covered. The  girl  had  a  typical  acute  myelitis  of  the 
lower  part  of  the  cord.  She  had  had  inherited  syphilis. 
jr^A  second  case  was  that  of  concussion-lesion,  with 
myelitis  and  secondary  degeneration,  reported  by  Dr. 
Bastian  ("Transactions  of  the  Royal  Medical  and  Chirurgi- 
cal  Society,"  June  25,  1867,  vol.  1.).  Here  the  patient 
died,  and  a  rupture  of  the  cord  in  the  cervical  enlarge- 
ment was  found  to  have  been  the  starting-point  of  the 
disease.     Mr.  Page  considers  this  case  unique. 

I  have  under  treatment  now  a  patient  suffering  from 
transverse  myelitis  and  descending  degeneration,  of  whom 
the  history  is  very  similar  to  that  of  Bastian's.  Before 
reading  Mr.  Page's  comments,  I  came  across  Bastian's 
case,  and  was  so  struck  with  its  clinical  resemblance  to 
my  own  that  I  referred  to  it  in  exhibiting  the  patient  to 
my  class  at  the  New  York  Post-Graduate  School 

Dr.  Edes  reports  (quoted  in  Hamilton's  "  Medical 
Jurisprudence,"  p.  357)  four  cases  of  postero-lateral 
sclerosis,  the  result  of  spinal  concussion. 

Petit,  in  his  work  upon  the  "  Relation  of  Locomotor 
Ataxia  and  Traumatism,"  shows  that  the  injuries  and  ac- 
cidents may  at*least  develop  tabes  in  the  predisposed. 

Althaus  in  his  recent  work  on  **  Scleroses  of  the 
Cord "  states  the  same. 

It  seems  to  me  to  be  proven  beyond  a  doubt,  despite 
Mr.  Page's  arguments,  that  external  violence  and  jars, 
apart  from  any  hemorrhage  or  other  lesion,  may  cause  an 
acute,  subacute,  or  a  chronic  myelitis,  with  softening  or 
secondary  degenerations.  Not  many  of  these  cases 
have  yet  been  reported,  because  they  are  rare  and  be- 


cause there  is  not  yet  a  widely  diffused  knowledge  of  the 
methods  by  which  the  different  forms  of  chronic  myelitis 
are  diagnosticated.  And  it  ought  perhaps  to  be  added 
that  a  certain  predisposition,  syphilitic  or  neurotic,  is 
necessary  for  the  development  by  traumatism  of  most 
of  these  forms. 

But  it  is  claimed  not  only  that  myelitis,  but  that  a 
chronic  meningitis  or  meningo-myelitis  may  be  set  up 
by  concussions  of  the  cord.  It  is  to  this  pathological 
class  that  Mr.  Erichsen  relegates  a  very  large  part  of  his 
reported  cases.  In  doing  this  he  had  undoubtedly  given 
a  more  serious  aspect  to  many  of  these  cases  than  they 
deserved.  Meningitis  and  myelitis  are,  as  we  have 
stated,  serious  diseases,  yet  the  cases  Mr.  Erichsen  de- 
scribes do  not  die. 

I  fully  agree  with  Mr.  Page  that  a  large  proportion  of 
these  cases,  when  analyzed,  can  be  shown  to  be  cases  of 
strain  or  rupture  of  muscular  and  ligamentous  structures, 
injury  to  nerves,  or  the  results  of  a  general  nervous 
shock,  and  that  the  spinal  cord  has  no  more  to  do  with 
the  disease  than  the  stomach. 

I  hesitate  to  say,  however,  that  Mr.  Erichsen  is  entirely 
wrong  in  his  pathology,  or  that  there  is  not  set  up  in  some 
of  these  cases  a  low  grade  of  meningeal  inflammation  or 
congestion  ;  or  even  if  there  be  not,  as  in  the  case  of 
Mr.  Jepson,  patches  of  softening. 

This  is  certain,  however,  that  heretofore  too  little 
stress  has  been  laid  upon  the  symptoms  produced  by 
neuritis,  strains,  and  general  nervous  shock. 

Regarding  these  points  some  illustrative  cases  other 
than  those  quoted  by  Erichsen  and  Page  may  be  found, 
Leyden  {Archiv  /•  Psychiatr,^  1878,  viii.,  p.  31,  quoted 
by  Hamilton)  reports  a  case  in  which  a  patient  suffered 
from  peripachymeningitis  and  compressive  myelitis  end- 
ing in  death. 

I  have  reported  a  case  of  cervical  pachymeningitis  in 
a  syphilitic  where  the  disease  was  undoubtedly  started 
up  by  a  severe  blow  on  the  neck  {^Journal  of  Nervous 
and  Mental  DisecueSy  January,  1882). 

Dr.  Allan  McLane  Hamilton  reports  a  case  (**  Medi- ' 
cal  Jurisprudence,"  p.  355,  New  York,  1883)  ^^  which 
he  states  that  there  was  undoubtedly  "  serious  organic 
change  in  the  brain  and  cord "  as  the  result  of  spinal 
concussion. 

IV.  As  to  the  visual  troubles,  I  doubt  very  much  if  the 
chronic  functional  disturbances  we  have  been  speaking 
of  can  ever  produce  any  real  organic  trouble  with  vision. 

Albutt,  I  believe,  speaks  of  a  chronic  meningeal  irri- 
tation, which  gradually  creeps  up  from  the  cord  to  the 
brain,  and  finally  affects,  by  contiguity,  the  eye.  I  believe, 
however,  that  there  may  be  asthenopia,  restricted  vision, 
hysterical  disturbances  of  same,  vascular  changes  in  the 
disc,  but  nothing  else,  unless  organic  disease  of  the  cord 
or  brain  sets  in.  Dr.  J.  G.  Johnson  gives  a  valuable 
summary  of  evidence  on  this  point.     Vide  bibliography. 

Turning  now  to  a  discussion  of  the  more  practical  and 
important  features  in  so-called  spinal  concussion,  I  would 
state  that  without  doubt  in  the  largest  class  of  troubles 
resulting  from  accident  and  injury  to  the  spine,  the  main 
source  of  the  symptoms  is  a  general  functional  nervous 
disturbance. 

The  fright,  excitement,''and'more  or  less  severe  bodily 
injury  produce  often  a  profound  shock.  From  this  the 
nervous  system  gradually  emerges  into  a  state  that  may  be 
broadly  characterized  as  one  of  asthenia,  morbid  irrita- 
bility, and  defective  inhibition.  The  patient  then  fur- 
nishes a  clinical  picture  familiar  to  all. 

Sleeplessness,  irritability,  states  of  depression,  defec- 
tive memory,  inability  to  do  mental  or  physical  work, 
headache,  tinnitus,  nervousness,  vasomotor  disturbances, 
excessive  sweating,  asthenopia,  large  pupils,  spinal  pain 
and  tenderness,  muscular  weakness,  tremor  and  twitch- 
ings, and  irregular  pulse,  are  the  ordinary  symptoms. 
Sometimes  pronounced  neuromimelic  disorders  develop. 
The  patient  shows  the  symptoms  of  so-called  spinal 
anaemia,  or  of  spinal  irritation,  or  he  develops  paralyses 


I 


620 


THE   MEDICAL  RECORD. 


[December  6,  i88^. 


hemianaesthesia,  and  various  hysterical  phenomena.  In 
nearly  all  cases  these  symptoms  are  subjective.  They 
correspond  with  those  of  neurasthenia,  as  described 
by  Beard,  Mitchell,  Erb,  Mobius,  and  Dowse,  or  with 
those  of  the  convalescent  stage  of  cerebral  concussion,  as 
described  by  Hutchinson ;  they  are  included  under  the 
neuromimetic  disorders  of  Paget,  and  they  have  been 
aptly  termed  railway  hysteria  and  hypochondriasis  by 
Dr.  Allan  McLane  Hamilton. 

It  is  these  cases  which  form  the  most  puzzling  prob- 
lems for  the  physician,  and  which  cause  him  the  greatest 
troubles  perhaps  bring  him  into  greatest  reproach  before 
the  court. 

This  is  due  partly  to  the  incompletely  developed  views, 
to  speak  mildly,  promulgated  of  late  years  regarding  the 
nature  of  spinal  injuries,  and  partly  to  the  natural  and 
inherent  difficulties  of  the  subject.  As  to  the  first  point, 
the  spinal  column  has  been  held  up  as  the  most  delicate, 
responsive,  and  hyperaesthetic  of  all  organs.  It  has  been 
made  the  focus  for  every  jar,  bruise,  or  shock  to  centre 
upon,  and  "  concussion  of  the  spine  "  has  been  the  shib- 
boleth of  every  frightened  passenger  and  prosecuting 
attorney  for  twenty  years.  As  Holmes  once  said  re- 
garding Bishop  Berkeley  and  his  belief  in  the  universal 
efficacy  of  tar-water :  "  Berkeley  believed  that  the  whole 
material  universe  was  nothing,  and  that  tar-water  was 
everything,"  so  in  a  measure  the  spinal  cord  has  been 
looked  upon  as  everything — ^brain,  muscle,  ligament,  and 
nerve  as  nothing. 

Not  long  ago,  through  the  kindness  of  my  friend  Dr. 
George  E.  Munroe,  I  was  called  to  see  three  women  who 
all  had  very  nearly  similar  symptoms,  viz.:  mentally  they 
were  profoundly  emotional  and  hysterical,  physically 
they  were  paraplegic,  or  nearly  so,  and  suffered  from 
sensitive  spines.  In  two  the  spinal  pain  and  tenderness 
were  so  very  marked  that  the  diagnosis  of  spinal  irrita- 
tion was  made ;  the  third  patient  had  what  was  termed 
spinal  anaemia.  This  last  patient  only  was  in  a  railway 
•  collision,  and  received  a  slight  jar,  but  no  serious  physi- 
cal injury.  The  other  two  received  severe  blows  on  the 
head,  causing  concussion  of  the  brain.  Thus  the  fright 
of  a  collision  in  one  case  produced  a  similar  state  to  that 
caused  by  the  blows  on  the  head  in  the  other  two.  But 
only  the  patient  who  was  in  the  railway  accident  was 
thought  to  have  "concussion  of  the  spine." 

It  may  be  laid  down  as  absolutely  established  now, 
that  railway  accidents  produce  severe  shocks  to  the  ner- 
vous system  which  make  persons  neurasthenic  or  hys- 
terical, oftener  the  former.  This  condition  is  a  real  patho- 
logical one,  and  the  sujfferers  are  unquestionably  some- 
times as  much  injured  as  if  they  had  had  a  broken  arm 
or  leg,  or  an  actual  injury  of  the  cord.  The  practical 
trouble  is  in  determining  how  ill  such  people  are,  how 
much  they  are  malingering,  how  much  the  prospect  of 
heavy  damages  unconsciously  or  consciously  affects  their 
symptoms,  how  much  predisposed  to  disease  they  were 
before  the  accident.  For  a  road  should  not  be  called  to 
account  because  it  does  not  provide  perfectly  for  the 
crippled,  the  paralytic,  and  the  valetudinarian. 

In  illustration  of  these  difficulties  my  learned  friend 
•  Dr.  Allan  McLane  Hamilton  records,  in  his  valuable 
work  on  "  Medical  Jurisprudence,"  the  history  of  a  patient 
of  mine  (whom  he  examined  for  a  railroad  company),  and 
adds  this  terminal  comment :  '*  This  man  is  an  undoubted 
malingerer."  In  opposition  to  this  view,  I  have  for  the 
three  years  since  his  accident  thought  him  to  have  been 
made  by  it  a  nuisance  to  his  family  and  a  burden  to  him- 
self on  account  of  his  change  of  disposition,  lessened  ca- 
pacity to  work,  and  sciatic  pains.  If  ever  I  attain  a 
position  which  will  justify  me  in  writing  a  medico-legal 
treatise,  I  shall  record  the  same  case  and  say  that  this 
man  was  undoubtedly  a  case  of  traumatic  neurasthenia 
complicated  with  neuritis.  But  who  is  ever  to  decide 
whether  my  book  will  be  right,  or  Dr.  Hamilton's  ? 

It  will  be  seen  that  it  is  an  important  matter  to  under- 
stand and  extend  the  means  of  diagnosing  these  conditions 


where  nearly  every  symptom  is  subjective.  Into  the 
discussion  of  this  I  cannot  enter,  but  would  call  attention 
to  the  occasional  evidence  of  hemianaesthesia  of  the  body 
and  of  the  special  senses  as  a  sign  of  hysteria.  Drs. 
G.  L.  Walton  and  J.  J.  Putnam  have  especially  drawn 
attention  to  these  signs,  and  to  the  occasional  very 
great  value  of  the  tuning-fork,  aesthesiometer,  and  visual 
tests. 

The  use  of  electricity  in  testing  muscular  and  nerve  ir- 
ritability  and  degeneration  when  carefully  applied  is  of 
the  greatest  value.  At  the  last  meeting  of  the  American 
Neurological  Association,  I  suggested  that  the  test  of 
diminished  or  increased  electrical  resistance  in  affected 
limbs  might  be  of  value  in  some  cases.  In  one  case  in 
which  I  tried  it,  the  alleged  lame  and  injured  limb  showed 
slight  diminished  electrical  irritability,  and  increased 
electrical  resistance  on  two  successive  trials  on  different 
days. 

The  matter  of  prognosis,  also,  calls  for  more  accurate 
determination.  Mr.  Page  is  inclined  to  take  a  rose-col- 
ored view  of  the  prognosis  in  these  cases.  He  thinks 
that  a  large  majority  recover,  and  that  nearly  all  tend  to 
recovery.  He  does  not  seem  to  have  met  cases  like 
those  of  Buzzard,*  or  where  any  organic  disease  finally 
set  in,  as  in  Edes'  cases,  Petit's,  and  my  own.  He  never 
has  met  any  serious  results  to  vision,  as  have  Wharton, 
Jones,  and  Erichsen. 

His  views  are  rather  too  hopeful,  and  decidedly  are  not 
always  borne  out  by  his  own  notes.  "  Patient  improving 
at  last  accounts,"  is  a  formula  given,  but  it  may  mean 
very  little  after  all.  Traumatic  neurasthenia,  or  railway 
hysteria,  is  generally  recovered  from  in  a  great  meas- 
ure. In  my  experience  traumatic  neurasthenia  is  the 
most  amenable  form  to  treatment.  But  it  is  very 
often  the  case  that  the  man  who  has  had  a  severe  ner- 
vous shock  is  never  entirely  the  same  that  he  was  before. 
This  is  particularly  the  case  if  he  has  reached  middle 
life,  or  is  of  a  neuropathic  constitution.  The  very  old 
and  the  very  young  seem  to  suffer  less.* 

The  object  of  my  paper  has  been  to  show  : 

1.  That  the  term  spinal  concussion  is  a  misleading, 
and  often  incorrect  one,  and  that  the  symptoms  which 
are  usually  associated  with  that  name  are  really  symp- 
toms of  traumatic  neurasthenia,"  hysteria,  and  hypochon- 
driasis, associated,  more  or  less,  with  symptoms  of  injury 
to  the  vertebral  ligaments  and  muscles,  and  to  the  spinal 
nerves  ;  that,  in  other  words,  spii)al  concussion  is  mental 
shock  and  physical  bruising. 

2.  That  this  traumatic  neurasthenia  is  in  a  measure  a 
real  disease,  though  it  is  very  hard  to  say  how  much  is 
real  and  how  much  the  patient  puts  on. 

3.  That  it  may  be,  and  often  is,  simulated,  and  that  it 
requires  the  greatest  care  to  detect  skilled  impostors. 

4.  That  we  need  more  objective  tests  for  the  purpose 
of  determining  the  existence  of  these  subjective  neuroses. 

5.  That  the  prognosis  of  railway  or  traumatic  neuras- 
thenia and  hysteria  is  very  good  so  far  as  steady  improve- 
ment is  concerned,  not  so  good  as  regards  complete  re- 
covery. 

6.  That  concussion  of  the  spinal  cord  alone,  followed 
by  temporary  loss  of  function,  or  by  myelitis,  does  oc- 
cur in  rare  instances. 

7.  That,  in  the  predisposed  at  least,  injuries  and  jars 
may  set  up  chronic  myelitis,  without  there  being  a  lesion 
of  the  spinal  column. 

8.  That   Mr.  Erichsen   has   in  his   book  on   "Spinal 


*  Nearly  twenty  years  a^o,  Dr.  T.  Buzzard  (Lancet,  1865  and  1867,  loc 
cit )  investigated  the  after-hisiorics  of  eight  cases  of  cerebral  and  spinal  conais- 
siun.  Two  to  four  years  later,  none  were  found  well,  and  one  had  died  of  pihlhi- 
sis.  The  same  author  cites  cases  apparently  showing  that  spinal  concussion  nuy 
develop  pneumonia,  phthisis,  imbeahty,  convulsions,  diabetes,  aneurism.  In  hs 
cases,  however,  there  seems  to  have  been  an  element  of  brain  injury. 

Moeli  (Archiv  f.  Psych)  relates  the  history  of  four  cases  of  railway  iojuxy 
followed  by  mental  disturbances. 

3  It  would  be  mteresting  to  learn  of  the  cures  which  railway  and  other  accidents 
sometimes  bring  about.     See  H.  Tuke's  work  on  Body  and  ftlind. 

*  The  term  "  traumatic  neurasthenia  "  covers  a  well-recugnized  sympiom-comnlex 
which,  in  some  cases,  includes  a  lithaemic  condition  produced  by  active,  healtiby 
persons  being  suddenly  obhged  to  lead  a  sedentary  life. 


December  6,  1884.] 


THE   MEDICAL  RECORD. 


621 


Concussion"  erroneously  attributed  functional  troubles 
to  the  results  of  organic  spinal  disease. 

9.  That  Mr.  Erichsen's  book  on  "  Spinal  Concussion  '* 
has  a  strong  tendency  erroneously  to  attribute  to  a  shak- 
ing of  the  spine  and  a  supposed  ensuing  meningitis, 
symptoms  really  due  to  mental  shock,  peripheral  injury, 
or  malingering. 


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Nitrite  of  Amyl  and  Abortion. — Dr.  Samuel  W. 
Francis  reports  that,  hawig  occasion  to  use  a  three-drop 
pearl  of  nitrite  of  amyl  to  restore  a  feeble  patient,  a 
young  woman  in  attendance — and  who,  unknown  to  him, 
had  been  pregnant  some  six  months — was  so  seriously 
aflfected  by  the  vapor  that  she  had  to  leave  the  room  ; 
and  for  several  hours  it  was  feared  that  she  would  abort. 
The  doctor  adds :  "  Might  it  not  be  well,  under  these 
circumstances,  to  study  the  action  of  nitrite  of  amyl  as  to 
its  influence  on  the  parturient  female  ?  " 


LEAD-POISONING.* 
By  R.  CHANNING  M.  PAGE,  M.D., 


NEW  YORK. 


Paroxysms  of  abdominal  pain  and  obstinate  constipa- 
tion are  the  prominent  symptoms  of  what  is  commonly 
called  lead  colic. 

It  is  unnecessary  to  mention  the  many  other  well- 
known  names  that  have  been  applied  to  this  condition. 
Sometimes,  however,  it  is  called  Madrid  colic,  but  ac- 
cording to  Larry  that  complaint  is  due  to  atmospheric 
vicissitudes  and  acid  beverages,  and  not  to  lead-poison- 
ing. The  same  may  be  said  of  the  so-called  West  India 
colic,  if  we  are  to  believe  Drs.  Chisholm  and  Thomson, 
who  resided  long  in  the  West  Indies.  The  symptoms 
of  lead  colic  had  been  described  from  early  times,  but 
the  real  cause  was  unknown  up  to  the  time  of  Stock- 
hausen,  of  Prussia,  who  first  suggested  it  in  a  treatise 
published  in  1656.  Afterward  Henkel  first  proved  by 
actual  experiment  that  lead  and  its  compounds  are  the 
sole  substances  which  produce  lead  colic' 

The  etiology  of  the  disease,  as  is  well  known,  is  the 
introduction  into  the  system  of  lead  in  some  form,  either 
through  the  skin,  the  air-passages,  or  the  stomach.  The 
various  ways  in  which  people  become  poisoned  with  lead 
are  well  known,  and  need  not  be  stated  here.  Suffice  it 
to  say  that  painters  who  work  inside  (dryers)  are  affected 
far  more  frequently  than  others.  This  is  partly  because 
they  are  compelled  to  work  with  doors  and  windows 
closed  at  all  seasons  of  the  year,  and  partly,  I  think,  be- 
cause the  paint  they  use  is  mixed  with  turpentine,  which 
is  a  highly  volatile  substance.  Outside  painters,  on  the 
contrary,  not  only  have  abundant  ventilation,  but  the 
paint  they  use  is  mixed  with  a  fixed  oil. 

A  pecson  once  attacked  is  more  liable  to  a  recurrence 
of  the  disease,  however  thoroughly  he  may  have  been 
cured  before  resuming'his  occupation. 

Men  are  much  more  frequently  attacked  than  women, 
for  the  obvious  reason  that  they  are  much  more  frequent- 
ly exposed  to  the  cause.  The  season  of  the  year  does 
not  appear  to  have  any  influence  in  producing  the  dis- 
ease. During  the  month  of  February,  188 1,  1  had  more 
cases  to  apply  to  me  for  treatment  than  at  any  previous 
time,  and  I  began  to  think  that  perhaps  in  cold  weather 
it  might  occur  more  frequently,  but  I  have  since  noticed 
that  fully  as  many  are  affected  in  warm  weather.  Inside 
painters  have  told  me  that  they  suffer  more  in  summer 
than  winter,  as  they  work  with  doors  and  windows  closed 
at  all  seasons.  Vegetation  suffers  near  lead  furnaces, 
and  cattle  and  hogs  in  the  neighborhood  die  firom  lead- 
poisoning.* 

The  symptoms  of  lead  colic  are  so  well  known  that  I 
need  not  repeat  them  all  here,  and  the  diagnosis  is  not 
difficult  Abdominal  pain  and  obstinate  constipation,  as 
already  stated,  are  the  prominent  features  of  an  attack. 
The  pain  is  sometimes  intermittent ;  at  others  it  is  never 
entirely  absent,  but  exacerbates  and  remits,  so  to  speak. 
The  obstinate  constipation  is  owing  to  an  entirely  differ- 
ent cause  from  that  which  produces  the  general  costive- 
ness  incident  to  lead-poisoning.  The  former  is  due  to 
the  pain,  as  we  shall  presently  endeavor  to  describe, 
and  sometimes  fails  to  be  overcome  by  drastic  cathartics  ; 
the  latter  is  associated  with  the  condition  of  general 
bad  health  that  has  been  brought  about,  and  often  yields 
to  the  ordinary  laxatives. 

Unless  the  patient  is  completely  cured,  and  especially 
if  he  continues  to  be  exposed  to  the  influence  of  the 
poison,  chronic  symptoms  appear  sooner  or  later.  He- 
sides  a  condition  of  general  bad  health  there  is  now 
paralysis  of  the  extensor  muscles  of  the  forearm,  causing 
what  is  commonly  called  drop-wrist  In  some  cases,  as 
among  miners,  inside  painters,  and  others  who  are  ex- 

1  Read  before  the  Northwestern  Medical  and  Surgical  Society,   New  York, 
Novemlier  a6»  1884. 
3  L.  Tanquerel  des  Planches  :  Lead  Diseases,  by  Dana,  p.  34.    1848. 
*  Wilson :  Monthly  Journal  of  Medical  Science,  Edinburgh,  May,  1852. 


622 


THE   MEDICAL  RECORD. 


[December  6,  1884, 


posed  to  the  vapors  of  lead,  tremors  are  developed 
resembling  paralysis  agitans.  In  other  cases  arthralgia 
occurs,  so  that  the  patient  imagines  that  he  has  rheu- 
matism of  the  joints.  These  cases  appear  to  be  com- 
paratively rare,  however,  since  of  twenty-six  cases  that 
applied  to  me  for  treatment  at  the  Northwestern  Dis- 
pensary, in  this  city,  only  two  had  tremor,  and  that  of  the 
upper  extremities,  and  one  had  arthralgia.  In  all  three 
cases  the  lead  cachexia  was  well  marked.  I  have  had  as 
yet  but  little  experience  with  lead  encephalopathy.  The 
so-called  blue  line  along  the  gums  was  ^rst  mentioned  by 
Dr.  Henry  Burton,  of  London,  in  1840.*  Since  then 
this  sign  has  been  insisted  upon  by  nearly  all  authors  on 
the  subject  as  diagnostic.  It  is  said  to  be  due  to  the 
chemical  action  on  lead  of  sulphuretted  hydrogen  gener- 
ated about  unclean  teeth.  For  although  the  sulphide 
(sulphuret)  of  lead  is  black,  under  certain  conditions  it 
may,  so  far  as  I  know,  appear  blue.  Nieraeyer,  how- 
ever, does  not  mention  any  blue  line  at  all,  but  says ' 
that  "the  gums  are  dark,  almost  slate-gray,  the  teeth 
themselves  being  discolored,"  a  condition  that  may 
evidently  exist  without  lead-poisoning.  Flint '  says  truth- 
fully that  the  blue  line  is  not  constant,  and  does  not 
occur  where  the  teeth  are  missing.  Taylor  *  says  that 
mercury  and  the  salts  of  silver  produce  this  blue  line, 
and  that  in  certain  cases  of  chronic  lead- poisoning 
it  may  be  absent.  All  the  blue  line  I  ever  found  existed 
as  frequently  without  lead-poisoning  as  with  it.  Bad 
and  unclean  teeth,  I  am  inclined  to  think,  will  produce 
this  so-called  blue  line  along  the  gums  independently  of 
lead-poisoning.  Even  if  it  can  be  due  to  this  cause,  it 
would  probably  be  absent  in  cases  so  slightly  affected  as 
to  give  rise  to  any  doubt  in  the  diagnosis.  Beyond  bieing 
an  occasional  clinical  curiosity,  therefore,  even  if  it  be 
that,  it  appears  to  be  of  little  or  no  importance. 

The  duration  of  an  attack  of  lead  colic  varies  in  dif- 
ferent cases  and  the  way  in  which  it  is  treated.  Thus 
under  proper  treatment  it  may  last  only  a  few  hours  or 
days  at  most,  whereas  if  let  alone,  or  in  those  cases 
where  the  patient  seeks  the  advice  of  a  druggist  and 
undertakes  his  own  treatment,  an  attack  may  last  in 
varying  degree  of  intensity  for  a  week,  or  even  in- 
definitely. The  symptoms  of  chronic  lead-poisoning,  on 
the  contrary,  even  under  the  best  treatment,  may  con- 
tinue for  weeks  and  sometimes  months.  I  once  treated 
a  patient  with  drop-wrist  steadily  for  five  months  before 
he  was  dured.  In  other  cases,  undoubtedly,  the  dura- 
tion is  much  longer,  especially  if  the  patient  continues  to 
be  exposed  to  the  poison. 

The  prognosis  is  nearly  always  favorable  except  in 
those  chronic  cases  where  general  tremor  has  resulted, 
or  where  some  grave  complication  has  arisen.  Thus  it 
is  said  that  a  patient  may  die  of  apoplexy,  or  in  an  epi- 
leptic convulsion,  during  an  attack  of  lead  colic,  or  from 
supervening  inflammation  in  some  of  the  abdominal 
viscera,  although  I  have  never  seen  any  of  these  cases. 
As  the  disease  becomes  chronic,  defective  nutrition,  gen- 
eral emaciation,  and  chronic  nephritis  with  a  fatal  result 
may  occur. 

The  pathology  of  lead-poisoning  may  be  said  to  be  yet 
a  subject  for  dispute.  It  is  quite  probable,  however, 
that  the  motor  cells  of  the  anterior  horns  of  the  gray 
substance  of  the  spinal  cord  are  primarily  affected.*  We 
know  that  strychnine  exalts  the  functions  of  these  cells, 
and  it  appears  that  lead,  on  the  contrary,  in  poisonous 
doses,  depresses  them.  The  muscles  become  affected 
accordingly.  Thus  in  certain  cases  there  is  paralysis  of 
the  extensor  muscles  of  the  forearm,  causing  the  charac- 
teristif  drop-wrist.  They  naturally  yield  first,  being 
weaker  than  the  flexors.  Subsequently,  however,  the 
paralysis  may  extend  to  other  muscles  of  the  body,  in- 

>  Medicsd  Gazette,  London,  vol.  xxv.,  p.  687. 

3  Practice,  seventh  American,  from  the  eighth  German  edition,  vol.  i.,  p.  619. 
x88o. 

*  Ibid.,  fifth  edition,  p.  543.     1884.  *  Poisons,  p.  400.     1JB75. 

*  Functions  of  the  Spinal  Cord,  by  M.  Allen  Starr,  A.M.,  M.I). :  American  Jour- 
nal of  Neurology  and  Psychiatry  for  August  and  November,  1884. 


eluding  flexors  also.     Hence  in  some  chronic  cases  we 
not  only  find  drop-wrist,  but  also  atrophy  of  the  flexor 
muscles  of  the  thenar  eminences.     There  is  reason  to 
believe  that  all  the  voluntary  muscles  may  become  more 
or  less  affected  as  the  disease  progresses,  only  it  is  more 
noticeable  in  the  extensors.     However  this  may  be,  I 
believe  with  Romberg  that  the  paroxysms  of  abdominal 
pain  are  neuralgic  in  character.     Constipation  cannot 
account  for  it,  since  a  patient  may  be  as  regular  in  his 
bowels  up  to  the  time  of  an  attack  of  lead  colic  as  could 
be  expected  in  one  who  was  already  in  a  state  of  general 
bad  health,  and  whose  intestinal  mucous  membrane  was 
under  the  astringent  influence  of  lead,  if  it  had  any.    The 
attack  once  commenced,  however,  the  bowels  become 
markedly  constipated,  and  as  the  pain  increases  in  se- 
verity  the   more   obstinate   is   the   constipation.     The 
reason  of  this  is  obvious.     For  as  in  pleurodynia,  sciatica, 
and  similar  painful  aflfections  muscular  movements  be- 
come limited,  so  does  intestinal  neuralgia  lessen  peris- 
taltic action.     If  the  pain  be  very  severe,  as  in  some 
cases,  peristaltic  action  is  lost  altogether,  so  that  the 
bowels  become  absolutely  motionless.     Hence  the  ob- 
stinate constipation.     To  give  drastic  cathartics  in  such 
cases,  therefore,  without  some  anodyne,  either  in  combi- 
nation or  previously  administered,  under  the  idea  that 
moving  the  bowels  will  cure  the  pain,  only  aggravates 
the  latter,  and  is  unscientific  practice.     Just  the  reverse 
of  this  is  the  truth.     Allay  the  pain  and  the  bowels  will 
often  move  without  a  cathartic.     I  usually  give  the  two 
combined,  however,  as  will  presently  be  described. 

It  is  clear  that  this  temporary  condition  of  obstinate 
constipation  is  not  due  to  lead  paralysis  and  atrophy  of 
the  muscular  coat  of  the  intestines,  otherwise  it  would  be 
more  permanent.  On  the  contrary  there  are  cases  with 
complete  drop-wrist  whose  bowels  are  perfectly  regular. 

Neither  can  pain  be  due  to  inflammation  of  the  intes- 
tinal mucous  membrane,  or  to  spasm  of  the  muscular 
coat  of  the  bowels,  otherwise,  instead  of  obstinate  consti- 
pation there  should  be  diarrhoea  or  dysentery.  Moreover, 
in  those  cases  where  post-mortem  examination  has  been 
made,  no  trace  of  inflammation  was  usually  found,  and.it 
is  hardly  possible  for  muscular  spasm  to  continue  without 
interruption  for  a  week,  as  lead  colic  sometimes  does. 
Collections  of  gas  in  the  intestines  cannot  account  for 
the  pain,  since  they  are  not  always  noticeably  present, 
nor  is  relief  usually  accompanied  by  marked  escape  of 
flatus,  as  in  wind  colic. 

In  regard  to  treatment,  prophylaxis  by  avoiding  ex- 
posure to  the  cause  as  far  as  practicable  is  of  the  first 
importance.  Milk,  as  recommended  by  some,  is  a  pro- 
phylactic so  far  as  it  is  an  article  of  nourishment.  For 
that  reason  it  is  better  than  dilute  sulphuric  acid,  which 
is  of  no  value  and  is  fit  only  for  washing  the  hands.  It  was 
first  introduced  by  Gendrin,  in  imitation  somewhat  of  the 
alum  treatment  originated  by  Grashuis,  on  the  theory 
that  it  would  produce  in  the  system  the  insoluble  sul- 
phate of  lead,  which  was  supposed  to  be  inert.  Clinical 
observation,  however,  disproves  this  theory.  The  judi- 
cious use  of  iodide  of  potassium,  producing  in  the  system 
the  soluble  iodide  of  lead,  which  is  readily  eliminated, 
would,  I  think,  be  a  much  better  plan.  Should  lead 
colic  occur,  however,  the  immediate  indications  are,  ob- 
viously, to  allay  pain  and,  on  general  principles,  to 
evacuate  the  bowels.  Perhaps  the  best  and  simplest 
method  of  treating  lead  colic  is  to  give  a  hypodermic  in- 
jection of  morphine,  repeating  it  if  necessary,  and  let  the 
bowels  take  care  of  themselves.  "  The  employment  of 
cathartics,"  says  Professor  Flings*  "maybe  useful  in  re- 
moving lead  contained  in  the  contents  of  the  alimentary 
canal.  Aside  from  this  object,  and  avoiding  incon- 
veniences from  constipation,  cathartics  are  not  indicated.*' 
A  free  stool,  however,  would  have  a  good  moral  effect 
on  the  patient,  who  is  apt  to  regard  the  constipation  as 
the  sole  cause  of  his  trouble.    And  as  it  will  be  necessary 


»  Op.  cit.,  p.  543. 


December  6,  1884.] 


THE   MEDICAL  RECORD. 


623 


to  regulate  the  bowels  in  order  to  facilitate  the  elimina- 
tion of  the  poison  from  the  system  while  improving  the 
patient's  general  condition,  it  is  just  as  well  to  begin  at 
once. 

Many  so-called  remedies  have  been  used  in  the  treat- 
ment of  this  disease,  including,  of  course,  mercury  and 
even  general  blood-letting.     In  1752  Grashuis,  a  Dutch 
physician,  conceived  the  idea  that  alum  (sulphate  of  alum 
and  potash,  or  ammonia)  would  be  a  good  remedy  in  this 
disease  on  account  of  the  sulphuric  acid  in  it,  which  he 
supposed  would  combine  with  the  lead  and  render  the 
latter  inert.     This  plan  has  since  been  followed  by 
various  physicians,  and  even  at  this  time  it  is  mentioned 
by  some  authors  as  a  specific  in  this  disease.     For  in- 
stance, Bartholow  *  says  :  **  For  the  treatment  of  the  colic 
of  some  cachexide  the  appropriate  remedy  for  the  cachexia 
will  be  necessary  :  for  example,  quinia  in  intermittent 
colic,  iodide  of  potassium  in  nocturnal  colic,  and  alum  in 
lead  colic."     Usually  about  a  drachm  is  given  four  times 
daily  in  water,  and  in  about  one  week  or  more  the  pa- 
tient may  get  better  or  not,  which  he  generally  does  any- 
how.     A  more  preposterous  plan  of  treatment  cannot 
well  be  imagined.   The  same  may  be  said  of  Epsom  salts 
(sulphate  of  magnesia),  which  is  undoubtedly  an  imita- 
tion of  the  alum  treatment.    The  fact  that  Epsom  salts 
contain  sulphuric  acid  does  not  make  it  preferable  as  a 
sah'ne  cathartic  in  this  disease  to  Rochelle  salts.     Both 
alum  and   salts  frequently  irritate  the  stomach,  and  the 
former  not  infrequently  produces  vomiting. 

Instead  of  losing  time  with  such  doubtful,  if  not  in- 
jurious means,  I  have  used,  with  nearly  invariable  suc- 
cess, a  combination  of  croton-oil  and  morphine  in  pill 
form,  as  has  been  suggested  by  various  authors.     I  have 
usually  ordered  one  to  two  drops  of  croton  oil  and  one 
grain  of  morphine  rubbed  up  with  a  sufficient  quantity  of 
extract  hyoscyamus  (or  some  inert  extract),  to  be  divided 
into  three  pills,  one  of  which  is  to  be  taken  eveiy  two 
hours  until  pain  is  allayed  and  the  bowels  move.   Loomis ' 
uses,  in  addition  to  croton  oil  and  morphine,  one-sixth 
grain  extract  belladonna  in  each  pill     The  croton  oil  is 
ready  to  act  about  the  time  that  the  patient  is  getting  re- 
lief from  pain  by  the  influence  of  the  morphine,  and  both 
indications  are  thus  met  at  the  same  time.     There  are 
other  cathartics  that  might  answer  the  same  purpose  if 
given  with  opium,  but  I  have  always  found  these  pills  to 
be  of  a  very  convenient  form  for  administration,  and  they 
do  not  irritate  the  stomach.     They  are  as  certain  a  rem- 
edy for  lead  colic  as  quinine  is  for  intermittent  fever,  and 
should  be   freshly  made  up.     One  or  two  are  generally 
sufficient,  and  rarely  have  I  found  it  necessary  to  give 
the  third.    Of  course  if  the  case  requires  it  a  hypodermic 
injection  of  morphine  may  be  given  at  once,  as  has  already 
been  said.     I  have  never  had  occasion  to  use  it.     I  do 
not  think  that  it  would  interfere  with  the  early  movement 
of  the  bowels,  and  if  it  did  I  do  not  believe  that  it  would 
make  any  difference.     Niemeyer '  says  that  **  there  is  no 
remedy  more  successful  than  opium  in  relieving  the  con- 
stipation of  lead  colic."     A  painter  once  informed  me  that 
whenever   he  found  obstinate  constipation  and  colicky 
pains  coming  on  he  would  take  thirty  drops  of  laudanum. 
In  this  way  he  not  only  allayed  pain,  but  soon  had  a 
copious  evacuation   from   the   bowels.     By  leaving   off 
work  for  a  couple  of  weeks  he  was  ready  to  begin  again. 
In  that  way  he  said  he  ''kept  out  of  the  hands  of  the 
doctors." 

The  treatment  should  not  end  with  curing  an  attack 
of  lead  colic,  however,  especially  if  the  patient  goes  back 
to  his  occupation.  The  poison  must  be  eliminated  from 
the  system,  otherwise  symptoms  of  chronic  lead-poison- 
ing will  appear  in  time,  if  indeed  they  have  not  already 
commenced. 

For  eliminating  the  poison  the  only  proper  remedy  is 
the  iodide  of  potassium.  This  drug  was  recommended 
for  the  first  time  in  this  disease  by  Melsens,  of  Paris,  in 


>  Pmctice,  fifUi  edition,  p.  xo8.     1883.         *  Ibid.,  first  edition,  p.  320. 
'  Op.  cit.,  p.  691. 


1884. 


1849.  ^y  chemical  action  it  produces  the  soluble  iodide 
of  lead  in  the  system,  as  already  stated,  and  its  undoubted 
efficacy  is  proved  by  the  well-known  fact  that  it  causes 
lead  to  appear  in  the  patient's  urine.*  I  always  give  the 
iodide  in  ten-grain  doses  three  times  daily,  and  have 
never  found  it  necessary  to  give  it  in  larger  doses.  The 
question  arises.  How  long  should  this  remedy  be  con- 
tinued ?  Where  the  case  is  not  of  long  standing,  and 
where  paralysis  has  not  occurred,  I  believe  that  six  weeks 
is  enough — it  being  understood  that  meantime  the  general 
health  must  be  attended  to,  and  that  the  patient  does  not 
continue  to  be  exposed  to  the  poison.  For  this  reason 
he  should  at  once  leave  off  work  and  endeavor  to  find 
some  other  employment  for  the  time.  But  where  drop- 
wrist  has  occurred,  I  have  kept  up  this  treatment  steadily 
for  three  months.  Even  in  the  worst  cases  I  have  never 
had  occasion  to  use  the  iodide  any  longer  than  that  if 
the  patient  obeyed  instructions  and  took  it  steadily.  I 
prefer  to  discontinue  it  then  and  put  the  patient  on  bark 
and  iron.  If  necessary,  however,  the  iodide  may  be  con- 
tinued for  a  longer  period  and  in  larger  doses.  I  have 
never  tried  the  sulphur  baths  and  have  never  found  them 
necessary. 

Iodide  of  potassium  eliminates  lead  from  the  system, 
but  it  does  not  restore  the  paralyzed  and  atrophied  mus- 
cles to  their  normal  condition.     For  this  purpose  elec- 
tricity is  the  proper  remedy,  although  dry-rubbing  and 
otherwise  stimulating  the  muscles  meantime  should  be 
practised.     At  no  time  during  treatment  is  the  induced 
(faradic,  which  is  subdivided  into  primary  and  secondary) 
current  to  be  preferred  to  the  constant  (galvanic,  contin- 
uous) current.     At  first  the  former  is  usually  of  no  bene- 
fit, since  in  many  cases  it  fails  to  cause  the  affected  mus- 
cles to  contract.     In   marked   cases,   where  all  other 
methods  of  applying  electricity  fail,  the  interrupted  con- 
stant current  should  be  used^  and  if  necessary  the  poles 
should  be  changed.     After  considerable  improvement  has 
taken  place  the  constant  current  without  the  interruptions 
may  be  used.     The  strength  of  the  current  should  be 
about  fifteen  to  twenty  cells,  according  to  circumstances.* 
If  the  interrupted  constant  current  be  used,  the  number 
of  interruptions  should  be  about  six  times  a  minute. 
Placing  the  negative  pole  over  the  musculo-spiral  nerve 
in  the  arm  (middle  cervical  vertebra — De  Watteville)  and 
the   positive  pole   successively  over  the   motor   points 
(bellies)  of  the  affected  muscles  of  the  forearm,  the  con- 
stant current,  interrupted  or  not  as  the  case  requires, 
should  be  used  for  about  two  minutes  for  each  muscle. 
As  the  case  improves  sufficiently  the  induced  may  be 
substituted   for  the   constant  current,  although   I  have 
never  seen  any  benefit  derived  from  the  change.     The 
applications  of  electricity  should  be  repeated  tliree  times 
a  week  (every  other  day)  until  a  complete  cure  is  effected. 
If  the  interrupted  constant  current  fails  to  cause  the 
affected  muscles  to  contract  at  first,  even  though  the  poles 
be  changed,  the  prognosis  is  less  favorable.     Such  cases 
appear  to  be  rare,  but  even  then  a  complete  cure  is  not 
to  be  despaired  of  without  further  trial.    The  applications 
of  electricity  should  be  repeated.     At  the  same  time  the 
iodide  of  potassium  should  be  systematically  administered 
with  a  view  to  eliminating  the  poison,  and  the  general 
health  should  be  attended  to.     If  then  the  interrupted 
constant  current  failed  to  cause  the  muscles  to  contract, 
the  case  might  be  regarded  as  hopeless. 

Of  the  twenty-six  cases  mentioned,  only  four  had  any- 
thing like  a  blue  line  along  the  gums.  Dr.  J.  C.  Mac- 
kenzie, of  this  city,  saw  most  of  these  cases  with  me.  I 
do  not  attribute  the  discoloration  in  those  four  cases 
to  the  sulphide  of  lead.  One  had  lead  tremor  of  the 
upper  extremities.  I  only  saw  him  once.  There  were 
seven  who  applied  while  they  had  lead  colic,  and  they  all 
recovered  without  difficulty.  There  were  eighteen  with 
lead  paralysis  to  a  greater  or  less  extent  Of  these 
two  were  affected  only  in  the  left  hand,  five  in  the  right. 


1  Flint :  op.  cit.,  p.  544* 

*  De  Watteville  :  Medical  Electricity,  second  edition,  p.  187. 


1884. 


624 


THE   MEDICAL   RECORD. 


[December  6,  1884. 


and  eleven  had  complete  double  drop- wrist.  In  those 
cases  where  one  hand  only  was  affected  the  paralysis 
was  not  so  marked  as  in  the  cases  of  double  drop-wrist, 
and  in  one  case  the  index  and  middle  fingers  of  the  right 
hand  were  only  affected,  the  former  much  more  marked- 
ly. Of  the  eleven  that  had  complete  double  drop-wrist, 
two  were  sent  to  hospital,  not  having  sufficient  means  to 
be  treated  outside.  One  of  these  had  tremor  of  the 
hands  and  atrophy  of  the  thenar  eminences.  Of  the  re- 
maining nine  with  double  drop-wrist,  eight  were  cured 
without  difficulty,  but  in  one  case  the  interrupted  con- 
stant current  failed  at  first  to  cause  the  affected  muscles 
of  the  right  hand  to  contract.  After  three  weeks'  sys- 
tematic administration  of  iodide  of  potassium  and  re- 
peated applications  of  electricity  they  began  to  respond. 
The  muscles  of  the  left  hand  responded  from  the  first. 
There  was  marked  double  drop-wrist  and  the  muscles  of 
the  thenar  and  hypothenar  eminences  were  much  atro- 
phied. This  patient  completely  recovered  after  five 
months'  treatment.  Eight  of  the  eleven  cases  having 
double  drop-wrist  stated  that  they  noticed  that  the  right 
hand  began  to  weaken  first,  and  generally  attributed  it 
to  getting  turpentine  on  that  hand,  while  three  did  not 
remember  which  hand  was  affected  first.  Of  seventeen 
cases  of  lead-poisoning  during  the  past  year  reported  to 
me  by  Dr.  Edwin  E.  Swift,  through  the  courtesy  of  Pro- 
fessor E.  C.  Seguin,  of  the  Department  for  Nervous 
Diseases,  Manhattan  Eye  and  Ear  Hospital,  in  this  city, 
six  had  the  so-called  blue  line  along  the  gums;  none 
were  affected  in  the  right  or  left  hand  alone ;  seven  were 
not  affected  with  paralysis ;  and  ten  were  affected  in 
both  hands.  Oi'  these,  four  are  reported  as  having  had 
paralysis  to  commence  first  in  the  right  hand  and  six 
doubtful.  Adding  these  ten  to  my  eighteen,  we  have 
twenty- eight  cases  of  lead  paralysis.  Of  these,  seventeen 
were  first  affected  in  the  right  hand,  two  in  the  left,  and 
nine  were  doubtful.  Twenty-one  cases  were  affected  in 
both  hands,  and  the  remaining  seven  would  doubtless 
have  become  so  in  time  if  they  had  not  applied  for 
treatment.  In  a  total  of  forty-three  cases  there  was  a 
so-called  blue  line  along  the  gums  in  ten,  and  none  in 
thirty-three ;  a  result  likely  to  be  found  in  an  equal  num- 
ber of  laboring  people  who  had  never  been  exposed  to 
the  influence  of  lead-poisoning. 

I  do  not  believe  that  there  was  any  local  effect  of  the 
poison  on  one  hand  in  preference  to  the  other.  It  may 
have  been  accidental  that  more  were  affected  in  the  right 
hand  than  the  left  in  the  above-mentioned  cases.  Or  it 
may  be  that  most  of  them,  being  right-handed,  merely 
noticed  it  in  the  right  hand  first,  though  it  may  have  ex- 
isted to  some  degree  in  the  left  hand  also.  For  the  same 
reason,  left-handed  people  might  be  likely  to  notice  it 
first  in  the  left  hand. 

31  West  Thirty-third  Strkbt,  November  a6,  1884. 


A  Reminiscence  of  the  Iniernational  Medical 
Congress. — On  the  first  day  of  the  great  gathering,  while 
the  different  nationalities  were  flockmg  into  the  Univer- 
sity porch,  they  encountered  on  the  steps  a  porter  dis- 
tributing small  rectangular  cards,  the  size  and  shape  of 
book-markers.  These  were  received  by  the  English  and 
Americans  with  an  amount  of  laughter  and  merriment 
utterly  unintelligible  to  their  colleagues  of  the  European 
continent.     On  these  cards  were  printed  the  following  : 

W.  C.  Stinck's, 
Bog  Papir  og  Kunsthandel, 

Amagertow  33, 
Kjobenhavn. 
Translated  into  what  Mark  Twain  calls  "  a  language  a 
Christian  can  understand,"  this  announcement  is  a  very 
prosaic  one.  The  first  line  is  the  respectable  shop- 
keeper's name,  which  in  Danish  has  not  its  English  mean- 
ing. The  remainder  is  simply  "  Dealer  in  Books,  Sta- 
tionery, and  Art,  33  Amager  Market,  Copenhagen." — 
M^d,  Press, 


VOMITING   IN   PREGNANCY. 
By  W.  gill  WYLIE,  M.D., 

professor   of   gynecology   in  the   new  YORK   POLYCLINIC,  AND  CVNSCOLOGIIT 
TO  BBLLSVUB  HOSPITAL,   NEW  YORK. 

In  the  spring  of  1879  I  was  studying  diseases  of  the 
cervix  uteri  in  preparing  a  paper  upon  "  Laceration  of 
the  Cervix  Uteri,"  and  I  came  across  Dr.  Edward  Cope- 
man's  paper  in  the  British  Medical  Journal  of  May  15, 
1878,  on  "  Dilatation  of  the  Os  Uteri  for  Vomiting  in 
Pregnancy.*'     About  this  time  I  had  two  cases  of  vomit- 
ing with  pregnancy,  and  had  tried  many  drugs  with  poor 
success.     One  of  these  was  a  multipara,  and  I  had  very 
little  trouble  in  introducing  the  index  finger  of  my  left 
hand  into  the  os  uteri  up  to  the  first  joint,  and  it  gave 
complete  relief.    The  other  patient  was  a  primapara  thai 
1  had  treated  for  retroversion,  and  had  become  pregnant 
while  wearing   the   pessary.    Notwithstanding  that  the 
uterus  was  held  in  good  position,  the  vomiting  was  very 
severe.     The  cervix  was  pointed,  hard,  and  had  a  slight 
erosion  of  mucous  membrane  around  the  os.     Without 
using  great  force  I  found   that  I  could  not  pass  my 
finger.     I  put  her  in  Sims'  position  and  with  a  uterine 
dilator  opened  the  cervix  by  gradually  dilating  it  for  a 
half  inch  or  more.     There  was  slight  pain  and  a  little 
bleeding,  but  no  real  disturbance.     The  vomiting  was 
somewhat  relieved,  but  not  cured.     After  an  inter\'al  of 
four  days  I  dilated  the  cervix  again,  going  pretty  well  up 
to  the  OS  internum  with  the  point  of  the  dilator.    After 
this  the  vomiting  ceased.     In  the  fall  of  the  same  year  a 
case  very  similar  to  the  latter  came  under  my  care ;  when 
I  examined  it  I  found  the  uterus  completely  retroverted 
and  the  fundus  fixed  under  the  ilio-synchondrosis  ;  1  re- 
placed the  uterus  and  kept  it  in  position  by  a  pessary ; 
the  backache  and  local  pain  were  completely  relieved, 
but  the  vomiting  grew  worse.    After  trying  various  reme- 
dies without  material  benefit,  I  dilated  the  cervix,  and 
after   the   second    dilatation    the   vomiting   completely 
ceased.     Since  then,  I  have  had  many  cases,  some  of 
them  extreme  cases  ;  one  where  the  patient  was  so  ill 
that  I  was  sent  for  to  bring  on  abortion  as  the  last  resort, 
and  in  all  relieved  the  vomiting  by  dilatation  and  local 
treatment,  except  in  two  instances,  one  a  patient  that 
left  town  after  one  dilatation,  and  the  other  was  a  hospi- 
tal case,  where  the  whole  vulva  and  vagina  were  com- 
pletely covered  with    inflamed  and   sensitive  venereal 
warts. 

Although  vomiting  in  pregnancy  is  so  common  that  it 
is  one  of  the  most  reliable  of  all  the  early  symptoms  of 
pregnancy,  after  a  close  study  of  many  cases  I  am  con- 
vinced that  marked  vomiting  m  pregnancy  is,  in  the  ma- 
jority of  instances,  due  to  an  abnormal  condition  of  the 
cervix  uteri.  The  cervix  may  be  the  seat  of  acute  dis- 
ease, or  the  tissues  are  abnormal  from  previous  disease 
or  imperfect  development  of  the  cervix,  and  in  the 
majority  of  cases  the  cause  of  the  vomiting  will  be  found 
in  the  cervix.  Not  long  since  a  handsome,  healthy  young 
woman  came  to  my  clinic  in  great  distress  about  her 
abdomen  growing  large — she  had  been  married  four  or 
five  months.  She  said  she  had  not  had  her  menses,  but  she 
could  not  be  pregnant,  for  she  had  not  had  any  morning 
sickness,  and  all  her  friends  said  it  must  be  a  tumor.  Oa 
examination  I  found  the  cervix  perfectly  healthy,  and  the 
uterus  enlarged  as  it  should  be  in  pregnancy  at  the  fifth 
month. 

Many  women  do  not  have  nausea  with  pregnancy,  and 
the  absence  of  that  symptom  indicates  a  healthy  cervix, 
and  its  presence  I  believe  nearly  always  indicates  local 
disease  or  an  abnormal  state,  the  result  of  disease  or  im- 
perfect development. 

In  looking  over  the  literature,  it  is  surprising  how  little 
has  been  done  in  the  way  of  local  treatment,  and  how 
much  women  have  been  dosed  with  almost  every  kind  of 
drug  for  it.  To-day,  in  our  best  text-books  on  obstetrics 
it  is  not  treated  as  a  symptom  indicating  disease,  but 
merely  as  one  of  the  symptoms  of  pregnancy,  and  local 


December  6,  1884.] 


THE  MEDICAL  RECORD. 


625 


treatment  may  be  referred  to,  but  it  is  not  advised.  No 
one  denies  how  serious  it  often  is,  and  that  now  and  then 
it  causes  death.  In  1873  ^^*  Alfred  H.  McClintock,  in 
a  paper  read  before  the  Dublin  Obstetrical  Society,  in 
which  he  advocated  induction  of  abortion  as  the  only 
thing  to  do  in  extreme  cases,  says  that  without  much 
trouble  he  had  collected  the  record  of  fifty  deaths 
from  vomiting  in  pregnancy,  and  he  reports  thirty-six 
cases  in  which  abortion  was  induced  as  a  last  resort,  with 
twenty-seven  recoveries  and  nine  deaths ;  but  he  had 
nothing  to  say  about  local  treatment. 

In  a  paper  before  the  London  Obstetrical  Society,  in 
1871,  on  "  Vomiting  in  Pregnancy:  Its  Cause  and  Treat- 
ment," Dr.  Graily  Hewitt  claims  that  the  severe  forms 
are  due  to  local  disease,  but  makes  the  mistake  of  attrib- 
uting it  all  to  his  hobby — displacements,  flexions,  and 
versions. 

In  the  London  Lancet  of  February,  1878,  Dr.  M.  O. 
Jones,  of  Chicago,  111.,  wrote  a  paper  on  **  Vomiting  in 
Pregnancy,"  and  advocated  in  certain  cases  the  local  ap- 
plication of  nitrate  of  silver  to  the  os  uteri  as  a  cure. 
In  some  cases  this  will  undoubtedly  stop  the  vomiting. 
Dr.  Copeman's  paper  came  out  in  the  same  year.  May, 
1878,  in  the  British  Medical  Journal^  and  was  followed 
by  a  number  of  articles  and  reports  of  cases  confirming 
Dr.  Copeman's  views.     In  1879,  whep  Dr.  Sims  returned 
fi'om  Europe,  I  had  two  or  three  cases  which  I  had  him 
see  as  typical  ones  treated  by  Dr.  Copeman's  method 
of  dilatation.     In  1880  he  wrote  a  paper  on  the  subject, 
and  it  appeared  in  the  Archives  of  Medicine,     In  tny 
paper  on  "  Laceration  of  the  Cervix,"  read  before  the 
County  Medical  Society,  i88r,  under  the  head  of  Pre- 
vention, I  said  :  "  When  a  woman  becomes  pregnant  it 
must  not  be  taken  for  granted  that  the  neck  of  the  uterus 
is  perfectly  healthy,  or  if  it  is  in  good  condition  at  this 
time,  that  it  will  remain  so  throughout  pregnancy." 

Morning  sickness  to  a  moderate  extent  may  occur 
without  any  perceptible  disease  of  the  cervix,  but,  as  a 
rule,  it  is  a  pretty  certain  indication  that  there  is  an  un- 
healthy condition  of  the  neck  of  the  uterus.  For  two 
years  past,  I  have  not  seen  a  single  case  of  this  distress- 
ing condition  that  did  not  yield  in  a  few 
days  to  local  treatment,  while  several  of  my 
cases  were  not  helped  by  the  usual  reme- 
dies. 

If,  during  pregnancy,  there  is  nausea,  leu- 
corrhea,  or  any  indication  of  disease  of  the 
cervix,  an  examination  should  be  made  and 
the  case  treated,  not  only  to  relieve  the 
S3m[iptoms,  but  in  order  to  get  the  neck 
o{  the  uterus  in  a  healthy  condition  before 
labor. 

The  danger  of  inducing  an  abortion  by 
treatment  is  by  no  means  as  great  as  I  at 
first  supposed  it  would  be,  and  I  think  that 
with  reasonable  care  many  more  cases  of 
abortion  and  premature  birth  could  be  ob- 
viated than  would  be  caused  by  the  treat- 
ment.     Applications  can  be  made  to   the 
cervix,  and  for  at  least  three-fifths  of  an  inch  | 
within   the  canal,  and  tepid  vaginal  injec-  \ 
tions  can  be  safely  used  during  pregnancy. 
For   the   relief  of  nausea,   I  have  found 
dilatation  of  the  canal  for  three-fifths  of  an  I 
inch  to  be,  so  far,  perfectly  successful  in  re-  | 
lieving  this  syniptom  and  in  softening  the 
hardened   condition  of  the  cervix  so  com-f 
monly  associated  with  it,  and  perhaps  caus-j  J 
ing  the  vomiting.     Sometimes  the  index  fin-;> 
ger    introduced   to   the   first  joint   will  answer,'  but  in 
many    cases,  especially  in    primaparae,  it  is   very   diffi- 
cult  to   get.  even  the  point  of  the  finger  into  the  cer- 
vix.    I  nov^  use  a  modified  uterine  dilator  bent  nearly 
at  right  angles,  so  that  not  more  than  three-fifths  of  an 
inch  can  enter  the  canal ;  it  is  opened  by  a  screw  ad- 
justment w^hich  enables  you  to  regulate  the  extent  of 


\i 


dilatation,  and  its  shape  makes  it  easy  to  introduce  it 
even  when  the  cervix  is,  as  it  often  is,  very  high  and  far 
back  in  the  pelvis.*  In  some  cases,  there  will  be  slight 
hemorrhage  after  even  moderate  dilatation,  and  usually 
one  dilatation  completely  relieves  all  vomiting.  After 
dilatation,  the  neck  soon  becomes  shorter  and  much  softer. 

I  caution  my  patients,  when  pregnant,  to  be  careful  at 
the  time  that  they  would  expect  to  have  their  menses  if 
not  pregnant,  and  to  be  especially  careful  if  any  of  the 
usual  premonitory  symptoms  should  become  manifest ; 
for  I  am  satisfied  that  at  this  time  abortion  or  premature 
labor  is  most  likely  to  occur. 

If  not  successful  in  correcting  any  trouble  of  the  cervix, 
and  there  is  any  discharge,  vaginal  injections  are  to  be 
used,  and  for  some  days  before  labor  is  expected  anti- 
septic injections  are  used  once  a  day.  In  all  cases  I 
have  the  nurse  come  early,  and  if  these  carbolized  injec- 
tions are  not  used  before,  one  is  given  at  the  first  indica- 
tions of  labor  beginning,  and  everything  must  be  in  readi- 
ness for  the  carrying  out  of  a  somewhat  modified  form  of 
Listerism  during  and  after  labor,  until  the  discharge 
ceases.  An  examination  is  carefully  made  of  the  cer- 
vix and  uterus  before  the  patient  is  allowed  to  sit  up. 
If  obstetricians  would  take  as  much  pains  to  prevent 
laceration  of  the  cervix  uteri  as  they  do  to  prevent  lacera- 
tion of  the  perineum,  much  would  be  done  toward  obviat- 
ing this  accident.  They  should  avoid  rupturing  the 
membranes  until  it  is  absolutely  necessary.  In  a  rigid 
OS,  carefully  and  slowly  assist  dilatation  with  elastic  di- 
lators. In  dryness  of  the  parts,  freely  use  lubricants. 
When  the  pains  are  very  powerful,  and  the  voluntary 
efforts  at  expulsion  violent,  the  latter  should  be  con- 
trolled, if  necessary,  by  chloroform  at  the  time  of  the 
head  passing  the  cervix,  and  one  or  more  fingers  be  kept 
against  the  head,  and  an  effort  made  to  regulate  and 
modify  the  more  violent  efforts  at  expulsion.  Sometimes 
an  opportunity  will  be  found  to  help  the  cervix  over  a 
part  of  the  head,  where  it  is  retarded  more  than  atjother 
points. 

It  is  true  that  many  cases  of  lacerated  cervix  give  the 
history  of  forceps  being  used,  but  this  may  be  due  to  the 
fact  that  those  conditions  which  necessitate  the  use  of 
forceps  are  often  the  same  in  which  a  laceration  of  the 
cervix  would  take  place  whether  the  forceps  are  used  or 
not  To  avoid  lacerating  the  cervix  by  the  use  of  for- 
ceps, it  is  well  to  dilate  the  cervix  as  much  as  can  safely 
be  done  before  they  are  applied,  to  decide  as  early  as 
possible  that  forceps  are  necessary,  and  to  handle  them 
skilfully,  adjusting  them  accurately,  and  pulling  steadily 
and  in  the  right  direction  and  at  the  right  time.  Forceps, 
timely  and  skilfully  applied  in  retarded  labor,  often  pre- 
vent sloughing  and  some  of  the  worst  forms  of  lacerated 
cervix. 

Anyone  who  has  watched  carefully  the  changes  that 
take  place  during  pregnancy,  can  readily  understand  that 
any  condition  of  the  tissues  of  the  cervix  which  prevented 
its  softening  might  cause  reflex  vomiting.  A  few  weeks 
after  impregnation  the  cervix  becomes  congested,  is 
longer  than  normal,  and  bluish  in  color;  by  the  second 
month  the  congestion  is  at  its  height,  and  the  mucous 
membrane  may  be  much  softer  than  normal,  but  under- 
neath it  hard  tissues  may  be  felt,  and  the  cervix  is  not 
completely  softened  until  after  the  fourth  month.  In  the 
later  months  it  may  be  so  soft  as  to  make  it  somewhat 
difficult  to  define  its  outlines,  and  the  os  internum  seems 
to  be  the  only  thing  which  prevents  an  escape  of  the 
contents  of  the  uterus.  A  week  or  so  before  labor  the 
cervix  may  be  stretched  and  flattened  to  such  an  extent 
that  it  cannot  be  defined  at  alL 

Infiltration,  congestion,  and  swelling  always  precede  this 
softening  process,  and  if  the  tissues  are  imperfectly  de- 
veloped, or  if  they  are  indurated  by  disease,  or  left  in- 
durated after  the  disease  has  subsided,  it  is  plain  that  the 
softening  process  cannot  take  place  normally.    If  there  is 

'  la  my  last  instnunene  represented  by  the  wood-cu^  die  sanew  is  left  out,  as  I 
find  the  hand  a  better  guide  as  to  dqpree  of  force  needed  to  dilate. 


626 


THE   MEDICAL   RECORD. 


[December  6. 1884, 


cystic  disease  of  the  glands  or  follicles  the  softening  can- 
not take  place  normally.  If  there  is  granular  erosion,  or 
hard  cicatrices  from  laceration,  or  diseased  everted  tissue, 
it  cannot  take  place  normally.  In  cases  of  subacute  ca- 
tarrh, there  is  often  hyperaesthesia  of  the  mucous  lining, 
and  deeper  tissues  may  be  hardened  and  changed,  and 
thus  the  softening  process  preparatory  to  enormous  ex- 
pansion cannot  normally  take  place,  and  reflex  vomiting 
is  the  result. 

I  admit  that  without  further  proof  the  above  would  not 
be  convincing,  but  if  the  following  plan  of  treatment  is 
adopted,  I  am  certain  that  nearly  every  case  of  vomiting, 
no  matter  how  severe,  can  be  cured  without  any  special 
medicine  being  used  by  the  mouth,  except  what  may  be 
needed  to  regulate  the  bowels  and  keep  the  general 
health  good. 

If  a  patient  comes  to  me  suffering  from  nausea  and 
vomiting,  and  there  are  other  symptoms  of  pregnancy, 
instead  of  dosing  her,  I  make  a  local  examination  and 
give  local  treatment  for  any  disease  of  the  cervix  that  I 
may  find.  If  there  is  no  active  disease  I  would  dilate 
the  cervix,  knowing  from  experience  how  frequently  it 
will  give  relief.  The  dilatation  should  not  be  made 
when  the  menses  would  be  due,  nor  when  any  of  the 
usual  premonitory  symptoms  of  the  menses  existed. 

The  vulva  and  vagina  are  carefully  washed  with  a  i  to 
3,000  solution  mercuric  bichloride,  I  then  dip  the  blades 
of  my  dilator  in  pure  carbolic  acid  and  shake  off  the  free 
acid  and  introduce  the  points  into  the  cervix  for  about 
half  an  inch,  and  slowly  dilate  until  the  blades  separate 
from  one-third  to  one-half  an  inch.  If  there  is  an  eroded 
or  everted  diseased  tissue  present,  I  touch  it  lightly  with 
an  applicator  that  has  been  dipped  in  pure  carbolic  acid. 
I  then,  with  a  powder-blower,  cover  the  cervix  with  a 
thin  layer  of  iodoform,  and  place  against  the  cervix  a  flat 
pledget  of  borated  absorbent  cotton  soaked  in  pure 
glycerine,  which  is  to  be  removed  in  twenty-four  hours 
by  means  of  a  short  string  attached  to  it  In  some  cases 
there  is  slight  pain,  but  in  most  cases  no  pain  or  real 
disturbance  whatever  is  produced.  As  a  rule,  this  will 
relieve  nausea ;  but  after  four  or  five  days,  if  there  is  still 
nausea,  I  repeat  the  dilatation  and  may  pass  the  dilator 
three -fourths  of  an  inch,  and  in  some  cases  where  the 
cervix  is  long,  even  more.  Very  rarely  will  more  than 
two  dilatations  be  needed.  In  some  cases  the  cervix  is 
so  patulous  that  dilatation  may  seem  to  be  useless,  but 
well  up  in  the  cervix  tight  bands  may  be  found,  and  when 
stretched  complete  relief  is  effected.  Even  where  the 
cervix  is  lacerated  and  apparently  open,  bands  may  be 
found,  and  when  stretched  relief  is  obtained.  It  is  easy 
in  such  cases  to  recognize  when  the  end  of  the  dilator 
comes  against  the  os  internum,  for  it  is  firmly  closed,  and 
by  passing  the  instrument  until  the  os  is  felt  and  then 
slightly  withdrawing  it,  dilatation  can  be  done  without 
much  risk.  In  severe  cases  the  cervix  may  be  of  a  very 
bluish-black  color.  The  glycerine  application  causes  a 
free  watery  discharge  and  relieves  this  congestion.  P  or- 
merly  I  used  nitrate  of  silver  for  granular  erosion,  but  I 
found  that  the  carbolic  acid  and  glycerine  has  an  equally 
good  effect 

If  there  is  a  doubt  about  the  amount  of  dilatation,  the 
best  test  is  to  put  the  patient  on  her  back,  and  when  the 
index  finger,  up  to- the  first  joint,  can  be  easily  passed 
into  the  cervix,  the  dilatation  is  sufficient.  Before  resort- 
ing to  abortion  in  any  case  where  dilatation  up  to  the  os 
internum  failed,  I  would  first  dilate  the  os  internum  and 
wait  long  enough  to  see  if  it  would  stop  the  vomiting, 
for  this  can  be  done  in  some  cases  without  abortion  nec- 
essarily following. 

Conclusions. — i.  That  nausea  and  vomiting,  or  morn- 
ing sickness  in  pregnancy,  should  not  be  considered  and 
treated  as  merely  one  of  the  symptoms  of  pregnancy, 
but,  as  a  rule,  as  indicating  an  abnormal  condition  of  the 
tissues  of  the  cervix  uteri,  due  to  imperfect  develop- 
ment, disease,  or  the  effect  of  disease  on  the  tissues  of  the 
cervix. 


2.  That  any  pathological  state  which  interferes  with 
the  softening  and  other  changes  which  the  cervix  un- 
dergoes  during  pregnancy,  may  cause  nauseal  vomiting. 

3.  That  in  most  cases  relief  is  obtained  by  freely  di- 
lating the  cervix  uteri  below  the  os  internum,  and  in 
many  instances  it  is  the  only  means  by  which  relief  can 
be  had.  It  is  true  that  inducing  abortion  will  give  relief 
but  to  accomplish  this  the  cervix  must  be  dilated. 

4.  That  in  many  cases  specific  medicines  given  by  the 
mouth  are  useless,  and,  as  a  rule,  should  not  be  used 
until  a  local  examination  is  made  and  the  indications  for 
local  treatment  ascertained. 


THE  LAW  GOVERNING  THE  COMPENSATION 
OF   PHYSICIANS. 

By  henry  a.  RILEY,  ESQ., 

NSW  VOKK  CITY. 

The  usual  and  proper  performance  of  the  duties  of  a 
physician  requires  him  to  answer  calls  for  medical  ser- 
vices at  times  and  under  conditions  when  it  will  be  im- 
possible, unfeeling,  or  at  least  indelicate  for  him  to  stop  to 
inquire  who  is  to  pay  him  for  such  services.  This  being 
the  case,  it  often  happens  that  the  physician  runs  a  great 
risk  of  losing  all  compensation  whatever,  owing  to  the 
lack  of  there  being  any  person  at  once  legally  responsible 
and  pecuniarily  able  to  pay. 

The  legal  questions  at  issue,  and  the  cases  decided  in 
the  courts  on  this  subject,  will  be  of  general  interest 

It  will,  however,  be  convenient  to  discuss  only  the 
question  of  the  responsibility  of  a  private  person  who  re- 
quests medical  services  for  some  one  else,  and  reserve 
until  another  time  the  consideration  of  the  case  where 
some  public  official  requests  the  medical  service,  and  the 
point  is  whether  his  request  binds  the  town  or  county. 

It  may  in  general  be  stated,  that  a  person  who  calls  a 
physician  to  attend  some  one  else  is  not  liable  for  the 
physician's  bills.  The  point  in  the  cases  almost  invari- 
ably turns  upon  the  question  whether  the  person  order- 
ing the  services  acted  for  himself,  or  as  agent  for  the 
sick  person,  and  the  view  the  physician  took  of  the  rela- 
tion between  them,  by  seemingly  holding  the  one  or  the 
other  liable. 

The  gist  of  the  law  of  agency  is  well  stated  by  Judge 
Daly,  of  the  New  York  Common  Pleas  Court,  as  follows : 
"  It  is  a  general  principle  of  the  law  of  agency  that  one 
who  procures  services  to  be  done  for  another,  is  not  him- 
self chargeable  as  the  debtor,  unless  he  omits  to  make 
known  his  principal,  or  erroneously  supposes  that  he 
has  authority,  or  exceeds  his  authority,  or  expressly  or 
implicitly  engages  to  be  answerable  either  by  directly 
promising  to  pay  for  them  if  rendered  ;  or  by  doing  or 
saying  something  which  justifies  the  person  who  is  to 
perform  them  in  supposing  that  the  one  who  applies  to 
him  engages  to  pay  for  them."  Buck  vs.  Amidon,  Hov 
Pr.  Rep.,  378. 

An  apparent  exception  to  this  rule,  making  the  person 
receiving  the  services  liable  for  them,  is  that  of  a  person 
who  requests  the  services  for  those  whom  he  is  under 
some  legal  obligation  to  support  or  care  for,  such  as  a 
husband  or  the  father  of  minor  children.  The  cases 
illustrative  of  these  points  will  be  instructive.  In  Eng- 
land, at  least  until  recently,  a  physician  could  not  col- 
lect by  law  from  any  one  for  his  services,  they  being  con- 
sidered as  rendered  gratuitously  without  there  was  an 
express  agreement  to  render  compensation.  A  curious 
case  showing  this,  is  Vertch  vs.  Russel,  3  Q.  B.,  928,  tried 
in  1842.  The  defendant  here  was  a  lady  of  moderate 
fortune,  who  requested  a  physician  to  attend  her  brother, 
who  was  ill  and  in  indigent  circumstances.  It  did  not 
appear  by  the  evidence  that  any  agreement  was  made  in 
advance  in  regard  to  the  matter,  but  after  a* time  she 
wrote  him  a  number  of  letters  in  which  are  these  ex- 
pressions :  "  As  your  account  against  me  for  aiiendancc 
upon  my  brother  must  be  formidable,  you  will  cWigeme 


December  6,  1884.] 


THE   MEDICAL   RECORD. 


627 


by  letting  me  have  it."  "  My  wish  is  to  present  you  with 
some  such  a  sum  as.  you  would  call  upon  me  to  pay  you." 
« I  do  not  know  what  you  would  deem,  under  the  cir- 
cumstances, a  suitable  acknowledgment."  *'  I  hope  you 
will  at  once  tell  me  what  sum  will  be  agreeable  to  you  to 
accept  from  me."  The  physician  named  ;^i5o,  which 
the  lady  thought  too  much,  and  oflfered  ;^^o  in  settle- 
ment. This  amount  was  declined  and  suit  brought  for 
the  larger  sum.  On  the  trial  a  verdict  was  given  for  the 
defendant,  which  was  afterward  affirmed.  The  ground  of 
the  decision  was  apparently  that  there  was  no  original 
contract  and  the  letters  were  not  sufficient  to  take  the 
place  of  such  contract.  From  the  rule  preventing  the 
physician  from  bringing  suit  without  some  agreement,  it 
is  clear  that  he  would  have  had  no  cause  of  action 
against  the  lady's  brother. 

In  Sellen  vs,  Norman,  4  Carr.  &  Payne,  80,  another 
English  case,  where  the  services  were  rendered  to  a  ser- 
vant, it  was  said  :  ''  It  seems  that  a  master  is  not  bound 
to  provide  a  menial  servant  with  medical  attendance  and 
medicines  during  sickness,  but  if  a  servant  fall  ill  and  the 
master  calls  in  his  own  medical  man  to  attend  such  ser- 
vant, the  master  will  not  be  allowed  to  deduct  the  charge 
for  such  medical  attendance  out  of  the  servant's  wages, 
unless  there  be  a  special  contract  between  the  master 
and  servant  that  he  should  do  so." 
-  This  case  is  an  apparent  exception  to  the  general  rule, 
owing  to  the  relation  of  master  and  servant.  This  rela- 
tion in  this  country  is  not  regarded  in  quite  the  same  light 
as  in  England,  and  it  is  a  question  how  the  courts  here 
would  decide  the  point :  there  do  not  seem  to  be  any 
cases  bringing  it  up. 

In  Boyd  vs,  Sappington,  4  Watts,  247,  a  Pennsylvania 
case  tried  in  1835,  there  was  a  request  by  a  father  to  a 
physician  to  attend  hts  son,  the  words  used  being :  '*  Doc- 
tor, you  must  come,  I  am  afraid  my  son  will  die." 

It  appeared  by  the  testimony  that  the  son  was  thirty- 
two  years  of  age,  and  in  business  for  himself.  The  court 
held  that  this  request  raised  no  implied  promise  on  the 
part  of  the  father  to  pay  for  the  physician's  services.  If 
a  stranger  had  called  the  doctor  it  would  have  been  a 
parallel  case  with  that  of  an  inn-keeper,  who  might  sum- 
mon a  physician  hastily  to  attend  a  sick  guest,  and  such 
a  person  would  not  be  liable.  Under  the  circumstances 
the  court  held  the  rule  to  be  the  same  as  if  the  father  had 
been  a  stranger.  It  was  said  ''  a  dififerent  principle  would 
be  very  pernicious,  as  but  very  few  would  be  willing  to 
run  the  risk  of  calling  in  the  aid  of  a  physician  where  the 
patient  was  a  stranger,  or  of  doubtful  ability  to  pay." 

In  Smith  vs.  Reddick,  5  Jones  L.,  342  (North  Caro- 
lina), the  plaintiff  brought  suit  for  services  as  a  physician, 
rendered  at  defendant's  request  to  a  third  person,  under 
these  circumstances :  Reddick  was  not  related,  it  would 
seem,  to  the  sick  person,  but  was  sent  by  him  for  a  Dr. 
Pettis,  but  not  finding  him,  called  upon  Dr.  Smith,  and 
said  :  '*  I  have  come  after  you  to  go  and  see  a  sick  man." 
Reddick   did  not  return  to  the  patient's   house.     The 
court  said  **  the  evidence  tended  to  show  that  the  plain- 
tiff was  aware  of  the  fact  that  the  defendant  acted  merely 
as  a  messenger,  and  did  not  intend  or  expect  to  make 
himself  personally  liable  for  the  services  which  were  to 
be  rendered  to  the  sick  man.     The  doctor  who  was  in 
attendance  explained  to  the  sick  man,  in  the  presence  of 
the  plaintiff,  what  had  occurred,  that  the  defendant,  who 
had  been  sent  for  Dr.  Pettis,  not  finding  him,  as  the  case 
was  urgent,  had  applied  to  the  plaintiff  to  come  in  his 
place,  and    the  plaintiff  would  assist  him  in  performing 
the   operation,  which  was  assented  to.     If  the  plaintiff 
was  not  willing  to  assist  at  the  instance  and  on  the  credit 
jf  the  sick  man,  it  was  his  duty  to  have  made  known  his 
>bjections.      To  hold  the  defendant  liable  under  these 
rircumstances,  would  deter  every  one  from  doing  the  chari- 
able  office  of  going  after  a  doctor  for  a  sick  neighbor.'' 

In  Buck  z/s.  Amidon,  41  How.  Pr.  Rep.  (New  York), 
;7o,  we  find  an  instructive  case.  The  plaintiff  was  a  dis- 
inguished  surgeon  of  New  York  City,  and  the  defendant 


a  well-known  business  man^  also  of  the  same  city.  The 
latter  received  a  telegram  from  his  brother  at  Groton, 
Conn. ,  saying  that  a  surgeon  must  at  once  be  sent  up,  as 
a  dangerous  operation  had  to  be  performed,  and  request- 
ing Dr.  Buck's  services.  He  then  went  to  see  Dr.  Buck, 
showed  him  the  telegram,  urged  him  to  go,  secured  his 
consent,  met  him  at  the  railway  depot,  and  accompanied 
him.  The  operation  was  very  skilfully  and  successfully 
performed,  and  when  asked  for  his  bill  Dr.  Buck  pre- 
sented his  charge  of  $400,  in  the  name  of  the  sick  man. 
The  patient  expressed  his  surprise  at  the  amount,  and  a 
short  time  afterward  payment  not  being  made.  Dr.  Buck 
wrote  to  him  as  follows  : 
**Mr.  J.  C.  Amidon,  Groton^  Conn.: 

"  Dear  Sir  :  After  waiting  a  reasonable  time  without 
hearing  from  you^  I  beg  leave  to  remind  you  that  it  is 
customary  to  settle  such  accounts  as  mine,  for  professional 
services  rendered  at  a  distance,  promptly.  Hoping  it 
will  receive  your  early  attention,  I  remain,"  etc. 

The  bill  remaining  unpaid.  Dr.  Buck  brought  suit  not 
against  J.  C.  Amidon,  but  against  his  brother,  who  had 
called  at  his  office  and  requested  the  services.  Dr.  Buck 
testified  on  the  trial  that  on  his  arrival  at  Groton,  he  had 
noticed  the  plain  way  of  living  shown  by  J.  C.  Amidon, 
and  said  he  felt  surprised  that  persons  in  such  circum- 
stances should  think  of  sending  to  New  York  for  a  sur- 
geon. These  circumstances  were  introduced  to  show 
that  the  patient  was  originally  regarded  by  Dr.  Buck  as 
his  debtor.  Suit  was  nevertheless  brought  against  his 
brother,  and  the  jury  gave  a  verdict  to  the  plaintiff  for 
the  full  amount  claimed.  This  verdict  was,  however,  re- 
versed on  appeal,  the  court  holding  that  it  would  be 
**  preposterous  to  say,  that  a  person  who  brings  a  mes- 
sage to  a  surgeon  from  the  attending  physician  of  a  pa- 
tient, requesting  him  to  come  and  perform  an  operation 
upon  the  patient,  is  by  the  mere  delivery  of  such  a  mes- 
sage, chargeable  with  the  obligation  of  paying  the  sur- 
geon for  his  services.  He  is  a  mere  agent  and  nothing 
more,  unless  he  communicates  the  message  in  such  a 
way,  or  does  or  says  something  that  fairly  warrants  the  - 
surgeon,  before  he  undertakes  the  service,  in  supposing 
that  he  is  the  person  who  is  to  pay  for  it,  and  in  this  re- 
spect it  can  make  no  difference  that  the  bearer  of  the 
message  happens  to  be  a  brother  of  the  patient."  The 
case  of  Crane  vs,  Baudouine,  55  N.  Y.,  256,  occurring 
in  1873,  ^s  a  case  in  the  New  York  Court  of  Appeals,  and 
is  the  most  authoritative  statement  of  the  law  as  it  is  in 
the  State.  The  circumstances  were  as  follows:  Mrs. 
Martine,  the  defendant's  grown-up  daughter,  was  removed 
from  her  own  house  to  be  under  her  mother's  personal  care. 
Shortly  afterward,  as  the  plaintiff  testifies,  Mr.  Martine 
called  and  said  that  the  defendant  (Mr.  Baudouine) 
wished  him  to  call  and  see  his  daughter.  Dr.  Crane  did 
so,  and  saw  the  defendant  each  day  during  his  visits,  left 
directions  as  to  the  proper  treatment  with  the  defendant, 
and  told  him  what  to  do.  He  further  testified  that  he 
did  not  know  that  Mrs.  Martine  was  married  until  a  con- 
siderable time  after  he  began  his  visits,  and  that  he 
charged  the  defendant  on  his  books  and  sent  him  a  bill. 
The  defendant  denied  that  he  had  ever  employed  the 
plaintiff  or  requested  any  person  to  call  on  him.  The 
referee  before  whom  the  case  was  first  tried,  decided  in 
favor  of  the  defendant.  This  judgment  was  reversed  on 
appeal,  but  on  a  second  appeal  the  original  judgment  was 
affirmed.  It  was  held,  that  the  daughter  being  married 
and  with  a  home  of  her  own,  had  no  claim  upon  the 
father,  and  that  the  fact  of  removal  to  his  house  for  bet- 
ter care  did  not  cast  any  obligation  of  support  upon  him. 
The  father  would,  moreover,  be  naturally  interested  in 
the  condition  of  his  daughter,  be  ready  to  receive  direc- 
tions as  to  treatment,  and  would  be  likely  to  repeat  to 
others  what  the  physician  might  have  said  ;  but  none  of 
these  things  would  warrant  the  implication  of  a  promise 
to  pay  for  the  medical  services,  unless  the  defendant  was 
under  some  legal  obligation  to  care  for  the  patient.  It 
is  said  that  the  "  acquiescence  of  one  in  the  rendering  of 


628 


THE   MEDICAL  RECORD. 


[December  6,  1884. 


service  or  benefit  to  another,  not  entitled  to  call  upon  hira 
therefor,  is  not  equivalent  to  an  acknowledgment  that 
it  is  rendered  at  his  request.  So  far  as  a  legal  responsi- 
bility was  concerned,  the  defendant,  though  the  father  of 
the  patient,  was  a  stranger  to  her  and  her  necessities. " 

Perhaps  the  only  case  sustaining  the  opposite  view 
here  presented  is  Bradley  vs.  Dodge,  45  How.  Pr.  Rep.,  57 
(New  York),  where  the  following  principle  is  enunciated  : 
"  Where  a  person  calls  at  the  office  of  a  physician,  and 
in  the  absence  of  the  latter  leaves  his  business  card, 
written  on  it,  *  Call  on  Mrs.  Day,  at  No.  769  Broadway,' 
and  leaves  the  card  with  a  clerk  in  the  office  with  a  re- 
quest to  hand  it  to  the  physician  and  to  tell  him  to 
•  conae  as  soon  as  possible,'  he  becomes  liable  to  pay  the 
physician's  bill  in  attending  upon  Mrs.  Day  in  pursuance 
of  such  message."  This  case  was  decided  before  that  of 
Crane  vs.  Baudouine,  55  New  York,  256,  and  in  an 
inferior  court,  so  it  can  hardly  be  considered  the  law  in 
New  York  State.  The  case,  moreover,  enjoys  the  very 
unusual  distinction  of  being  assailed  by  the  court  re- 
porter as  bad  law  in  a  vigorous  note,  from  which  we  take 
the  following  extract :  **  Let  us  see  how  this  thing  works : 
we  will  take  as  an  illustration  an  almost  every-day 
occurrence  arising  in  the  country. 

**  A.  B.  is  taken  suddenly  and  seriously  ill  in  the  night-time 
and  sends  to  his  neighbor,  C.  D.,  living  in  the  next  house 
to  his,  to  have  him  go  after  the  doctor  as  soon  as  he  can, 
for  he  is  in  great  pain  and  distress.  C.  D.  jumps  out  of 
bed  without  hesitation  and  hastily  dresses  himself,  and 
goes  out  to  his  barn  and  takes  a  horse  from  the  stable, 
and  not  waiting  to  put  on  a  saddle  or  bridle,  jumps  on  to 
the  horse  with  the  halter  only,  puts  him  at  full  speed  for 
the  doctor's  office,  some  two  or  three  miles  distant.  On 
arriving  there  he  finds  the  doctor  absent  from  home,  but 
his  clerk  is  there,  and  C.  D.  at  once  says,  *  Tell  the  doctor 
to  call  on  A.  B.,  who  has  been  taken  suddenly  sick ;  tell 
him  to  come  as  soon  as  possible.' 

**  In  accordance  with  this  message  the  doctor  calls 
upon  A.  B.,  and  prescribes  for  and  attends  him  profes- 
sionally for  several  days.  After  a  reasonable  time  the 
doctor  sends  in  his  bill  to  A.  B.,  and  it  not  bemg  paid  as 
soon  as  the  doctor  desires,  he  calls  on  C.  D.  and  requests 
him  to  pay  the  bill.  C.  D.,  with  perfect  astonishment 
asks  why  he  is  to  pay  it.  The  doctor  informs  him  that 
he  made  himself  liable  to  pay  the  bill  because,  when  he 
delivered  the  message,  he  did  not  tell  the  clerk  that  he 
came  for  the  doctor  by  the  request  of  A.  B.,  nor  that  he 
acted  as  agent  of  A.  B.  in  delivering  his  message.  *  Well,' 
says  C.  D.,  *  the  fact  was  I  did  go  at  the  request  of  A.  B., 
and  merely  acted  as  his  agent  in  delivering  the  message, 
and  I  will  swear  to  these  facts  if  necessary.'  The  doctor 
insists  that  it  will  do  him  no  good  if  he  should  give  such 
testimony,  for  the  law  is  settled  on  that  point,  as  just 
such  a  case  has  recently  been  decided  in  New  York 
under  just  such  a  state  of  facts,  where  the  jury  in  the 
Justice's  Court  found  a  verdict  for  the  doctor  for  the 
amount  of  his  bill,  and  on  appeal  by  the  defendant  to  the 
General  Term  of  the  New  York  Common  Pleas,  that 
court  unanimously  sustained  the  verdict  of  the  jury  and 
affirmed  the  judgment  of  the  court  below.  'Well,'  says 
C.  D.,  'if  that  is  the  law,  I  think  I  will  wait  a  while  before 
I  go  after  a  doctor  again  as  an  act  of  neighborly  kind- 
ness.' " 

In  recapitulation  it  may  be  said,  that  the  nearly  unan- 
imous testimony  of  the  law-books  is  to  the  effect  that  a 
person  who  requests  a  physician  to  render  medical 
services  to  another  does  not  himself  become  liable  for 
the  physician's  compensation,  unless  he  promises  to  make 
such  compensation  before  the  services  are  rendered,  or 
unless  he  is  under  some  legal  obligation  to  care  for  the 
person  in  whose  behalf  the  services  are  rendered. 


Hydrochlorate  of  Cocaine. — Want  of  space  has 
crowded  out  several  interesting  items  concerning  the  use 
of  this  drug  in  dentistry,  minor  surgery,  and  laryngology. 


gtrogress  fst  plcdical  Science* 

Changes  of  Hemoglobin. — In  a  memoir  on  the  sub- 
stances which  change  haemoglobin,  and  especially  those 
which  convert  it  into  methsemoglobin,  Dr.  Hayem  ar- 
rives at  the  following  conclusions  :  Haemoglobin  gives 
the  blood  its  characteristic  redness,  preserves  its  re- 
spiratory capacity,  or,  in  other  words,  its  property  of 
absorbing  oxygen,  so  long  as  it  is  not  chemically  changed. 
The  most  complete  chemical  change  it  can  undergo  is 
conversion  into  methaemoglobin.  This  substance  is  of 
a  brownish  color.  When  shaken  in  contact  with  air 
it  does  not  absorb  oxygen.  Potassium-ferrocyanide  and 
potassium-chloride  both  convert  haemoglobin  into  meth». 
moglobin;  these  substances  have  been  used  for  many 
years  therapeutically.;  recently  nitrite  of  amyl  and  nitrite 
of  soda,  which  have  also  this  property,  have  been  em- 
ployed. Hayem  proposed  to  ascertain  how  it  is  that 
considerable  doses  of  these  medicines  can  be  adminis- 
tered without  leading  to  a  change  in  the  haemoglobin ; 
also,  when  it  does  undergo  an  alteration,  and  death  does 
not  result,  by  what  process  the  blood  is  freed  from 
the  methaemoglobin.  Although  haemoglobin  dissolved 
or  rendered  soluble  by  the  coagulation  of  blood  has  the 
same  respiratory  capacity  as  the  haemoglobin  of  blood- 
corpuscles,  there  is  an  important  difference  in  behavior 
between  these  two  varieties  in  presence  of  the  substances 
which  provoke  the  formation  of  methaemoglobin.  The 
haemoglobin  of  red  blood-corpuscles  is  indifferent  to  the 
action  of  those  substances  which  convert  dissolved  haemo- 
globin into  methaemoglobin.  Submitted  to  the  influence 
of  nitrite  of  amyl  vapor,  the  haemoglobin  of  blood-cor- 
puscles is  rapidly  converted  into  methaemoglobin,  which 
reabsorbs  oxygen  ;  whereas  dissolved  haemoglobin,  con- 
verted into  methaemoglobin,  is  permanent,  and  persists 
until  the  blood  putrefies. 

Weigert's  Method  of  Staining  the  Brain  and 
Cord. — A  solution  of  haematoxylin  is  prepared  with  water 
and  alcohol.  The  sections  are  kept  immersed  in  it  dur- 
ing an  hour,  and  the  temperature  is  maintained  between 
104°  and  122°  F.  They  are  then  removed  from  the  so- 
lution, washed,  and  placed  for  three  hours  in  a  two  per 
cent,  alkaline  solution,  or  in  one  of  potassium  ferrocyar 
nide.  Afterward  they  are  submitted  to  the  influence  of 
alcohol,  xylol,  and  Canada  balsam  as  in  the  ustial  method. 
In  sections  thus  prepared,  nerve-fibres  with  a  myeline 
sheath  are  stained  blue,  the  neuroglia  pale  yellow,  and 
the  ganglia  cells  brown.  This  method  throws  into  relief 
the  nerve-fibres  with  a  myeline  sheath.  In  preparations 
of  tabes  dorsalis,  Clarke's  columns  appear  as  light  rings 
against  a  dark  background;  microscopic  examination 
shows  that  a  large  quantity  of  nerve-fibres  with  a  my- 
eline sheath  have  disappeared. 

The  Treatment  of  Acne  in  the  Male  by  ^he 
Cold  Urethral  Sound. — Dr.  Sherwell,  of  Brooklyn, 
believes  that  acne  and  rosacea,  either  alone  or  combined, 
depend  in  almost  every  instance  upon  conditions  reflected 
from  the  sexual  or  digestive  apparatus,  and  in  the  rela- 
tive order  as  given ;  and  that  even  the  red  face  and  nose 
of  the  coachman,  of  whom  Hebra  speaks,  are  only  inten- 
sified, not  created,  by  the  external  irritation  of  biting 
winds,  etc.  His  theory  of  the  etiology  of  the  more  pro- 
nounced forms  of  acne,  as  the  tubercular  variety,  and  rosa- 
cea, is  that  nine  out  of  ten  cases  are  caused  by  congestioD 
of  the  mucous  membranes  of  some  of  the  viscera  spoken 
of,  probably  passive  in  character.  Why  they  should  be 
reflected  upon  the  face  he  does  not  know,  and  can  iom 
no  opinion,  any  more  than  he  ,can  in  urticaria,  which 
arises,  in  his  belief,  from  a  more'  active  and  ephemeral 
but  similar  condition  of  the  gastro-intesrinal  mucous 
membrane  in  the  same  relative  number  of  cases.  He 
thinks  it  probable,  however,  that  the  mucous  irritation 
arid  consequent  congestion  is  situate  higher  up  in  the 
alimentary  canal  in  urticaria.      In  these  cases,  too,  it 


December  6,  1884.] 


THE  MEDICAL  RECORD. 


629 


might  be  difficult  to  explain  why  the  efflorescences  are 
almost  always  situate  on  the  trunk  and  limbs.  It  will  be 
seen  in  the  foregoing  how  far  he  is  removed  from  the 
Marsyan-like  dogma  of  the  Viennese  school,  and  not 
alone  in  respect  to  these  diseases,  but  in  regard  to  others, 
as,  for  instance,  eczemas  of  the  infant,  or  child ;  in  those 
cases  he  pays  quite  as  much  attention  to  the  prima  viae 
as  to  the  skin,  considering  the  trouble  as  springing  very 
often,  if  not  generally,  from  gastro-intestinal  irritations. 
In  short,  he  believes  in  the  complete  analogy  between 
the  skin  and  mucous  membranes,  and  thinks  their  re- 
flected action  is  much  more  common  and  important  than 
many  authors  would  have  us  believe.  He  recommends 
in  persistent  cases  of  acne  and  rosacea  in  the  male  sub- 
ject, the  use  of  the  cold  urethral  sound,  and  that  too  with 
some  degree  of  diligence.  He  does  not,  of  course,  mean 
by  this  that  proper  topical  measures  to  the  parts  affected 
are  not  to  be  used  in  conjunction  therewith ;  or  that  tonic, 
cathartic,  dietetic,  and  hygienic  measures  and  principles 
to  meet  common-sense  indications  should  be  omitted. — 
Journal  Cutaneous  and  Venereal  Diseases^  November, 
1884. 

Elephantiasis  Scroti. — ^A  tumor  of  the  scrotum, 
weighing  forty-two  pounds,  was  successfully  removed  at 
the  Prince  Alfred  Hospital,  Sydney.     The  patient  was 
a  white  man,  twenty-four  years  of  age,  with  a  good  family 
history.     He  had  resided  where  elephantiasis  is  unknown. 
At  the  age  of  six  years,  an  enormously  hypertrophied 
prepuce  was  removed.     At  the  age  of  twelve  years  he  re- 
ceived a  blow  on  the  scrotum,  followed  by  a  painless  en- 
largement, and  at  the  same  time  he  had  an  attack  of 
chyluria.     From  this  time  on  there  were  frequent  febrile 
attacks,    chyluria,   and  gradual  increase  of  the  tumor, 
until  the  penis  was  lost  to  view.    Urinary  sinuses  were 
also    formed.      Repeated    examination    of   the    blood 
showed  absence  of  filarise.     Leucocytes,  however,  were 
in  excess,  and  the  red  corpuscles  appeared  swollen  and 
did  not  form  rouleaux.     The  operation  left  both  penis 
and  testicles,  and  was  accomplished  with  little  loss  of 
blood  by  the  use  of  Esmarch's  roller  and  india-rubber 
compressor.     The  tumor  was  composed  of  dense  white 
fibrous  tissues,   interspersed   with    patches   of   adenoid 
growth*      It  contained  numerous  enlarged  blood-vessels, 
and    dilated  lymph  channels.     There  were   patches  of 
thickened  homy  epidermis,  excessive  deposit  of  pigment 
in  the  rete,  and  the  stratum  granulosum  was  increased  in 
thickness. — Australasian  Medical  Gazette,  June  15, 1884. 

Thk  Relations  of  Hysteria  with  Scrofula  and 
Tuberculosis. — Professor  Grosset,  of  the  Montpellier 
School  of  Medicine,  concludes  a  series  of  articles  on  this 
subject  (^Brainy  part  xxvi.,  1884)  by  the  following  sum- 
mary :   "  Tuberculosis,  like  all  other  diatheses,  is  an  es- 
sentially general  and  constitutional  disorder  ;  pulmonary 
phthisis  is  but  one  of  its  manifestations.     It  may  show 
itself  as   a  neurosis,  and  more  particularly  as  hysteria. 
Just  as  chorea  is  often  a  rheumatic  disease,  angina  pec- 
toris a  gouty  disease,  thus  hysteria  may  be  a  tubercular 
disease,  taking  the  word  tubercular  in  its  nosological,  not 
in  its  anatomical  sense.     In  speaking  of  hysteria  as  a  tu- 
bercular disease,  therefore,  we  do  not  assume  the  exist- 
ence of  tubercular  matter  in  the  nerve-centres,  for  we  do 
not  look  upon  tubercles  as  pathognomonic  of  the   dia- 
thesiSy  which  exists  without  them,  as  they  may  exist  with- 
out it.     The  tubercular  diathesis  is  essentially  hereditary, 
but  may  be  understood  only  if  it  be  followed  up  in  fami- 
lies under  its  various  manifestations  from  generation  to 
generation.     We  then  see  how  hysteria  may  represent 
<liathesis  in  one  of  the  members  of  the  family  as  meningi- 
tis may  do  in  another,  or  Pott's  disease  in  a  third.     Be- 
-sides  such  cases,  in  which  hysteria  is  the  sole  manifesta- 
tion of  the  diathesis,  there  are  others  where  the  same 
individual  presents,  simultaneously  or  successively,  the 
two  orders  of  manifestations,  pulmonary  and  neurotic. 
We  then  witness  the  typical  phenomena  which  character- 
ize other  Protean  diseases ;  the  two  orders  of  symptoms 


alternate  and  replace  one  another ;  or  if  they  be  simul- 
taneous, influence  and  modify  one  another,  until  one  of 
them  gets  the  upper  hand.  In  other  words,  the  mutual 
relations  between  the  phthisis  and  hysteria  of  the  tuber- 
cular diathesis  are  like  those  between  the  cerebral  and 
abdominal  symptoms  of  typhoid  fever,  or  between  the 
visceral  and  articular  manifestations  of  gout.  These  re- 
marks concerning  hysteria  and  phthisis  form  but  a  frag- 
ment of  a  great  and  true  chapter  concerning  the  relation- 
ship of  all  neuroses,  and  even  of  all  nervous  diseases,  to 
the  diatheses  and  general  diseases.  If  we  cannot  under- 
stand the  neuroses  without  peceiving  their  mutual  rela- 
tions, if  the  consideration  of  the  ^  neuropathic  family^  is 
indispensable  for  securing  a  clear  grasp  of  the  phenomena 
of  neuropathology,  it  is  yet  necessary  to  go  still  further 
and  complete  all  this  by  the  conception  of  the  *  diathesic 
family^  outside  of  which  we  shall  find  nothing  but  isola- 
ted, scattered,  meaningless  units.  Hitherto  the  neurotic 
element  of  hysteria  has  much  too  exclusively  attracted 
attention;  the  diathesic  element  has  not  been  met  by 
treatment.  Though  we  have  no  specifics  against  diatheses 
(except  in  the  case  of  syphilis),  we  nevertheless  have  va- 
rious rational  means  to  deal  with  them.  The  treatment 
of  rheumatism  is  not  that  of  scrofula,  nor  that  of  tubercu- 
losis. Hence,  it  is  not  indifferent  to  know  whether  a 
neurosis  depends  upon  the  one  or  the  other  constitutional 
state.  Three  categories  of  indications  will  have  to  be 
fulfilled  in  the  full  treatment  of  hysteria.  First,  the  ac- 
tual symptoms  are  to  be  met  with  appropriate  measures, 
such  as  ovarian  compression,  ether  inhalations,  sesthesioge- 
nous  applications,  etc.  Second,  the  state  of  the  nervous 
system,  which  is  to  be  modified  at  any  cost :  hydrother- 
apy is  often  useful ;  change  of  surroundings ;  electric- 
ity, galvanic,  but  more  especially  static.  We  have  little 
faith  in  the  bromides.  Third,  the  diathesis  forms  the  fun- 
damental ground  for  a  chronic  exhibition  of  arsenic,  sul- 
phur, alkalies,  chloride  of  gold,  mineral  waters,  etc.  Un- 
less these  three  orders  of  indications  be  duly  taken  into 
account,  our  measures,  based  upon  a  superficial  diagnosis, 
must  necessarily  remain  sterile." 

Rational  Treatment  of  Typhoid. — Dr.  Rial,  under 
the  above  title,  describes  in  L  Union  M/dicale^  Septem- 
ber 28,  1884,  a  method  of  treating  typhoid  fever,  which 
consists  principally  in  the  administration  of  lar^e  doses  of 
subnitrate  of  bismuth.  He  claims  that  it  dismfects  the 
intestinal  canal,  and  prevents  putrefactive  changes  by 
fixing  the  sulphuric  acid,  free  or  nascent,  and  changing  it 
into  an  insoluble,  inoffensive,  black  sulphate.  Any  sub- 
stance employed  to  prevent  or  destroy  putrefaction  in  the 
intestinal  canal  must  be  a  powder  insoluble  in  the  digest- 
ive tract,  inoffensive  in  itself,  but  having  a  real  chemical 
action  on  the  putrid  matter.  The  subnitrate  of  bismuth 
he  has  found  to  fulfil  these  conditions  better  than  any 
other  agent.  He  administers  it  as  follows  :  The  first  day 
he  gives  a  starch  clyster  containing  two  and  a  half 
drachms  of  the  bismuth,  and  by  the  mouth,  from  five  to 
six  drachms  within  an  hour  in  divided  doses.  The  second 
day  this  same  quantity  is  given  by  the  mouth,  but  the 
doses  are  extended  through  the  twenty-four  hours.  This 
is  continued  daily  until  toward  the  end  of  the  treatment, 
the  dejections,  becoming  less  and  less  black,  contain 
particles  of  the  white  bismuth,  when  the  daily  dose  can 
be  gradually  decreased.  The  diarrhoea  is  usually  arrested. 
If  constipation  exists,  sulphate  of  soda  in  doses  of  3  ij*  to 
3  iv.,  by  the  mouth  or  rectum,  may  be  given.  He  cites 
three  successful  cases  in  children  where  he  has  employed 
this  treatment. 


PsYCHE-OLOGY. — One  day  last  summer  two  boys  were 
rowing  past  the  Riverside  Hospital,  on  Blackwell's  Isl- 
and. As  they  passed  close  to  the  Board  of  Health  boat 
lying  at  the  wharf,  one  of  them  rested  on  his  oars,  and 
spelling  out  her  name,  P-s-y-c-h-e,  pronounced  it  "  fish.'' 
**  That  don't  spell  *  fish,'  you  great  idiot,*'  shouted  the 
other,  "  that  spells  *  Physic ;'  it's  the  doctor's  boat." 


630 


THE  MEDICAL  RECORD. 


[December  6,  1884. 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 

New  York,  December  6,  1884. 


RECENT   CONTRIBUTIONS    TO    GASTRIC 
PATHOLOGY. 

A  NUMBER  of  contributions  have  of  late  been  made  to 
the  subject  of  gastric  disturbances.  It  was  in  1878  that 
Leube  first  (after  Beard)  called  attention  to  the  subject 
of  nervous  dyspepsia,  so-called  ;  and  a  little  later  Julius 
Glax  and  R.  Burkart  wrote  monographs  regarding  it. 
Leyden  and  Krafft-Ebing  have  also  called  attention  to 
certain  gastric  neuroses  found  in  spinal  irritation  and  as 
the  result  of  onanism.  Quite  recently  Leube,  at  the 
meeting  of  the  Congress  of  Internal  Medicine,  brought 
up  the  subject  of  nervous  dyspepsia  again,  and  both  he 
and  Edinger  have  made  important  contributions  to  the 
methods  of  diagnosis.  Clifford  Allbutt's  Gulstonian 
lectures  are  most  suggestive  as  regards  the  subject  of 
gastric  neuroses,  while  very  recently  Bouchard,  S6e,  and 
Mathieu  have  written  upon  gastric  dilatation,  and 
Glazinski  and  Jaworski  have  made  an  interesting  pre- 
liminary communication  upon  the  physical  methods  of 
diagnosticating  stomach  disease. 

A  perusal  of  the  various  communications  above  re- 
ferred to  leads  to  the  impression  that  great  strides  have 
been  taken  in  gastric  pathology  during  the  last  five 
years.  But  it  is  equally  certain  that  almost  no  definite 
and  fixed  results  have  yet  been  obtained.  It  would  be 
useless  to  attempt  any  generalization,  therefore,  as  regards 
the  present  state  of  our  knowledge  of  the  pathology  of 
the  subject  We  shall,  however,  present  to  our  readers 
an  analysis  of  some  of  these  later  contributions  since 
they  show  that  certain  lines  have  been  laid  down, 
working  along  which,  pathology  will  in  no  long  period 
of  time  reach  something  positive  as  well  as  practi- 
cal 

Professor  Leube's  paper  {Centralblatt  fur  Klinischt 
Medicin^  January  5,  1884),  in  which  he  lays  down  rules 
for  the  examination  of  the  stomach  contents,  has  already 
been  given  in  substance  in  this  journal.' 

A  preliminary  contribution  covering  similar  ground, 
by  Drs.  A.  Glazinski  and  W.  Jaworski,  of  Cracow,  has 
appeared  in  the  Berliner  Klinischer  Wochenschrift  of 
August  18,  1884.  These  authors  have  made  examina- 
tions of  the  action  of  the  gastric  juice  in  two  hundred 
cases  of  health  and  disease.  Their  method  was  as  fol- 
lows :  the  person  experimented  upon,  having  fasted  till 
the  stomach  was  empty,  is  given  the  white  of  a  hard- 

>  The  Mkdicai.  Record.  April  xa,  1884,  pw  405. 


boiled  egg  and  loo  c.cm.  of  distilled  water.  He  then 
remains  quiet  for  an  hour  and  a  quarter. 

At  the  end  of  this  time,  by  means  of  a  soft  syphon 
tube,  100  ccm.  of  water  are  introduced  into  the  stomach, 
and  the  whole  contents  syphoned  out  and  preserved  for 
examination.  More  water  is  then  introduced  and  re: 
moved  in  order  to  be  sure  that  nothing  remains  in  the 
stomach  cavity.  If  the  digestion  was  healthy  the  follow- 
ing conditions  were  found  : 

1.  No  pieces  of  albumen  were  returned  through  the 
syphon. 

2.  The  stomach  juice  is  clear  or  opalescent.  It  is 
neutral  or  feebly  acid  in  reaction,  and  contains,  as  shown 
by  methyl-violet,  no  hydrochloric  acid. 

3.  The  filtrate  gives  none  of  the  reactions  for  synto- 
nin  or  peptone.  On  the  addition  of  a  little  hydrochlo- 
ric acid  it  digests,  in  less  than  seven  hours,  a  very  small 
piece  of  albumen. 

4.  Under  the  microscope  the  fluid  withdrawn  shows 
no  ferment-organisms  or  free  nuclei. 

If,  despite  the  fact  that  the  foregoing  conditions  are 
found,  some  dyspeptic  trouble  is  complained  of,  a  second 
examination  is  to  be  made,  but  in  this  case,  only  half 
an  hour  after  the  ingestion  of  the  albumen.  In  healthy 
stomachs  at  this  time  the  following  ought,  according  to 
our  authors,  to  be  found : 

1.  About  half  of  the  albumen  comes  away  with  the 
fluid,  and  the  pieces  will  be  found  swollen  and  their  bor- 
ders frayed. 

2.  The  filtrate  is  strongly  acid  and  shows  the  presence 
of  HCl.  It  also  shows  the  presence  of  syntonin  and 
gives  a  moderately  strong  reaction  for  peptone. 

3.  The  filtrate  digests  albumen  without  the  addition  <A 
any  acid. 

4.  Under  the  microscope  no  ferment-organisms  or 
free  nuclei  are  visible. 

On  the  other  hand,  in  pathological  conditions  it  is 
found : 

•  I.  That  the  albumen  ingested  remains  in  the  stomach 
much  longer  than  an  hour  and  a  quarter,  and  this  is  what 
most  frequently  occurs.  Sometimes  the  albumen  is 
swollen  and  partly  digested;  at  other  times,  when  the 
gastric  juice  is  absent,  there  is  hardly  any  change. 

2.  The  stomach  contents  are  cloudy,  of  a  yellowish- 
green  or  bluish  color,  and  mixed  with  greenish-yellow 
flocculL 

At  the  end  of  half  an  hour  the  stomach  contents  are 
sometimes  much  more  strongly  acid,  sometimes  less  acid 
than  normal.  After  an  hour  and  a  quarter,  the  filtrate,  if 
any  albumen  is  present,  is  usually  more  acid  than  normaL 
After  half  an  hour  the  filtrate  may  or  may  not  contain 
peptone.  After  an  hour  and  a  quarter  the  fluid  contains 
peptone.  Microscopic  examination  shows  the  presence 
of  mucous  corpuscles  colored  with  bile-pigment  and  fer- 
ment-organisms, or  free  nuclei. 

The  authors  advise  that  after  examinations  have  been 
made  in  the  manner  laid  down  by  them,  tests  of  the  vital 
capacity  and  contractility  of  the  stomach  according  to 
the  method  of  Jaworski  should  be  made*  If  no  physical 
signs  of  disturbed  digestion  exist,  then  the  gastric  symp- 
toms must  be  referred  to  a  nervous  basis. 

The  article  of  Leube  upon  nervous  dyspepsia,  read  at 
the  Congress  of  Internal  Medicine,  has  been  given  in  de- 


December  6,  1884.] 


THE   MEDICAL  RECORD. 


631 


tail  in  The  Record  (May  31,  1884,  P*  621).  The  attempt 
to  giv^e  to  nervous  dyspepsia  a  distinct  nosological  status 
was  not  received  with  favor,  and  it  may  be  stated  that 
German  writers  generally  show  an  inclination  to  abandon 
the  term  nervous  dyspepsia  for  a  broader  one. 

The  article  by  Professor  Bouchard  is  in  the  form  of  a 
lecture  delivered  before  the  Hospitals  Medical  Society 
of  Paris  on  June  13th,  and  is  most  suggestive.  He 
claims  that  gastric  dilatation  is  of  very  frequent  occur- 
rence. Indeed  he  finds  it  in  one  case  out  of  three.  But 
the  main  part  of  his  paper  is  devoted  to  an  attempt  to 
explain  the  so-called  reflex  phenomena  of  dyspepsia  as 
well  as  many  of  the  concomitant  symptoms,  by  assuming 
that  the  fermenting  food  generates  poisons  and  causes  a 
true  toxaemia. 

In  dyspepsia  then  we  must  look  out  for  a  toxaemic 
condition,  just  as  in  renal  disease  we  must  watch  for 
uraemia.  This  view,  which  was  suggested  first,  we  believe, 
\>ySer\2Ltox{Beriiner  Klinischer  Wochenschrifi^  1868,  No. 
4),  is  based  by  its  author  on  a  study  of  two  hundred  and 
twenty  cases.  It  is  in  harmony  with  the  present  ten- 
dency of  pathologists  to  reduce  to  the  minimum  the  re- 
flex and  sympathetic  processes  as  causes  of  disease. 

An  important  contribution  to  gastric  pathology  has 
been  made  by  Professor  Germain  S^e,  and  Dr.  Albert 
Mathieu  in  the  Revue  de  Mtdecine,  Nos.  8  and  9,  1884. 

These  writers  treat  of  atonic  dilatation  of  the  stomach, 
which  they  consider  as  does  Bouchard,  to  be  a  very  com- 
mon condition.  They  believe  also  that  many  of  the 
cases  of  **  nervous  dyspepsia,"  as  described  by  I^eube, 
should  really  come  under  this  head.  Atonic  dilatation 
is  not  produced  by  mechanical  detention,  as  is  usually 
stated,  but  rather  it  is  the  result  of  an  adynamic  state  of 
the  general  system.  The  pathology  of  gastric  dilatation 
\&  thus  comparable  to  that  of  certain  forms  of  cardiac 
dilatation.  Both  are  expressions  of  myasthenia.  During 
and  after  adynamic  fevers,  or  as  the  restdt  of  profound 
anaemia,  or  in  conditions  of  mental  depression,  gastric 
dilatation  occurs.  Psychical  causes  are  quite  prominent' 
in  this  affection,  ranking  only  second  in  frequency. 
MM.  S^e  and  Mathieu  give  an  elaborate  array  of  cases, 
and  discuss  the  symptomatology  and  diagnosis. 

The  chief  symptoms  are  flatulence,  pains,  vomiting, 
constipation,  dyspepsia,  and  reactive  efifects  upon  the 
general  system. 

In  the  matter  of  diagnosis  the  authors  are  inclined  to 
treat  with  derision  some  of  the  "  fantastic  "  methods  of 
physical  exploration  suggested  by  the  Germans.  Careful 
comparative  examinations  by  percussion,  after  the  intro- 
duction of  eiOfervescing  powders,  and  then  of  pure  water, 
are  specially  recommended.  Percussion  without  these 
measures  cannot  of  itself  decide  the  diagnosis.  Auscul- 
tation and  succussion  furnish  also  some  corroborative 
signs.  For  the  many  details  of  this  valuable  paper,  how- 
ever, we  must  refer  our  readers  to  the  originals. 


TETANUS  INFANTUM. 

In  considering  the  comparative  frequency  and  great  fatal- 
ity of  the  first  kinesio-neurosis  of  life,  it  seems  strange 
that  we  have  not  more  definite  and  satisfactory  knowl- 
edge of  its  etiology.  The  mere  fact  that  many  very ' 
diverse  causes  have  been  given  by  good  observers  shows 
pretty  conclusively  that  no  one  of  them  is  always  opera- 


tive. The  most  satisfactory  way  to  reach  a  correct  con- 
ception of  this  peculiar  condition  is  first  to  consider  the 
nervous  status  of  the  infant  in  general,  and  then  in  each 
case  to  carefully  seek  out  the  immediate  irritant.  What, 
then,  constitutes  the  physiological  predisposition  to  this 
severe  and  fatal  tonic  spasm  of  early  infancy?  The 
peculiar  anatomical  arrangement  of  the  nervous  system 
at  the  beginning  of  life  is  well  known,  and  explains  the 
physiological  phenomena  seen  at  this  time.  Although 
the  brain  is  comparatively  large  in  size  in  proportion  to 
other  organs,  its  condition  is  immature.  It  is  soft  from 
the  imniense  amount  of  water  it  contains,  light  in  color, 
with  the  gray  substance  and  convolutions  undeveloped. 
As  a  result  the  functions  of  the  cerebrum  are  largely  in 
abeyance.  The  spinal  cord,  on  the  other  hand,  the  first 
formed  nervous  structure  of  the  foetus,  has  at  birth  a 
large  development  and  a  marked  functional  activity.  As 
reflex  action  is  one  of  the  principal  characteristics  of  the 
cord,  it  follows  that  in  early  life  this  kind  of  activity  must 
overshadow  all  voluntary  forms  of  motion.  Moreover,  at 
this  time  reflex  action  is  not  strongly  held  in  check  by 
cerebral  inhibition.  As  the  infant  grows  and  the  gray 
matter  and  convolutions  become  more  developed,  its 
nervous  system  reaches  a  condition  of  more  stable 
equilibrium  ;  but  during  the  first  days  of  life,  with  active, 
readily  irritated  spinal  centres,  and  a  watery  brain  incapa^ 
ble  of  much  controlling  energy,  the  only  wonder  is  that 
reflex  motor  disturbances  are  not  more  frequently  seen. 

There  are  many  ways  in  which  irritants  may  act  on  the 
unstable  nervous  S3rstem  and  produce  a  tetanus.  In  this 
affection,  as  in  eclampsia,  the  source  of  disturbance  must 
be  carefully  sought  out  and,  if  possible,  removed.  Irrita^ 
tion  and  inflammation  of  the  umbilical  vessels  or  um- 
bilicus have  frequently  been  noted  by  different  observers. 
Sometimes  retained  meconium  in  the  intestines  appears 
to  be  the  source  of  trouble.  A  condition  of  personal  and 
domestic  filth,  the  infant  being  allowed  to  remain  sur- 
rounded by  its  fermenting  excreta,  or  even  impure  air 
and  various  atmospheric  disturbances,  have  seemed  to  be 
sufiicient  to  upset  the  impressible  nervous  system  of  the 
young  infant  and  bring  on  a  tetanic  spasm.  Sometimes 
violence  to  the  cerebro-spinal  axis  during  parturition  is 
the  starting-point  of  trouble ;  in  other  cases  meningitis 
may  be  found.  One  of  the  late  ideas  is  that  an  adherent 
prepuce  may  be  a  factor  in  causing  the  disease.  There 
are  thus  many  general  and  local  agencies  that,  under 
favorable  conditions,  are  capable  of  acting  on  the  easily 
excited  spinal  cord  and  motor  nerves,  to  the  production 
of  general  or  partial  tetanus.  Perhaps  the  most  remark- 
able contribution  to  the  literature  of  this  subject  appeared 
in  1846,  in  an  article  by  Dr.  J.  Marion  Sims  in  the 
American  Journal  of  the  Medical  Sciences.  This  distin-^ 
guished  writer  then  first  advanced  the  idea  that  tetanus 
was  caused  by  a  centric  disturbance  due  to  pressure  from 
an  inward  displacement  of  the  occipital  bone.  This  dis^ 
placement  may  at  times  be  very  considerable ;  again  it 
may  bd  so  slight  as  to  require  careful  examination  for  its 
detection.  The  pressure  exerted  by  the  occipital  or 
parietal  bones  extends  itself  on  the  pons,  medulla  ob- 
longata, and  cord,  with  a  resultant  spasm.  This  explana^ 
tion  of  the  phenomena  of  infantile  tetanus  did  not  at  the 
time  meet  with  a  favorable  reception  by  the  profession^ 
and  has  since  been  almost  forgotten.    There  has  lately 


t 


632 


THE   MEDICAL  RECORD. 


[December  6,  1884. 


appeared  a  monograph  by  Dr.  J,  F.  Hartigan,  in  which 
the  original  views  of  Dr.  Sims  are  again  advanced  and 
fortified  by  cases  and  autopsies.     Histories  are  given  of 
forty-nine  cases  in  all,  some  seen  before  and  some  after 
death.     Six  of  these  cases  that  were  seen  early  recovered 
under  postural  treatment.     In  twenty-five  cases  autopsies 
were  made,  in  which  a  generally  uniform  post-mortem 
condition  of  congestion  and  extravasation  of  the  brain 
and  cord  was  found.     No  other  internal  lesion  was  ob- 
served except  at  times  an  engorgement  of  the  lungs. 
Finally,  eighteen  cases  are  given  in  which  a  history  was 
obtained  after  death,  although  some  were  seen  before  the 
fatal  result,  but  where  post-mortem  examination  was  not 
allowed.     One  factor  in  connection  with  all  these  cases 
that  the  author  especially  brings  out  is  that  there  was 
very  generally  found  a  depression  of  the  occipital  bone. 
The  relation  between  the  arrangement  of  the  bones  ex- 
ternally and  the  extravasation  found  internally  at  the 
autopsies,  has  afforded  occasion  for  generalizing  as  to 
trause  and  effect,  also  to  confirm  the  idea  advanced  so 
long  ago  by  Dr.  Sims.     If  we  have  here  the  only  true 
pathology  of  tetanus  infantum,  the  treatment  of  this  fatal 
malady  will  be  simple  and  frequently  successful.  Although 
a  depressed  occipital  bone  is  physiological .  during  the 
parturient  state,  if  it  persists  after  birth  it  soon  becomes 
pathological,  and  must  be  relieved  by  reducing  the  dis- 
placement and  thus  saving  the  cerebro-spinal  axis  from 
injurious  pressure.   Unfortunately,  however,  while  literary 
medicine  is  often  so  beautifully  exact  and  satisfactory, 
clinical  medicine  is  full  of  doubt  and  perplexity.     Many 
excellent  observers  have  not  been  able  to  discover  any 
noticeable  displacement  of  the  occipital  bone  at  the  be- 
ginning of  the  disease,  and  if  seen  later  it  may  sometimes 
be  simply  the  result  of  brain  shrinkage  accompanying  the 
rapid  general  atrophy.   The  tetanic  spasm,  by  greatly  in- 
terfering with  respiration  and  circulation,  would  naturally 
produce  the  congestions  and  ecchymoses  found  on  post- 
mortem examination  in  the  cerebro-spinal  axis  and  lungs. 
Doubtless  a  primary  inward  displacement  of  the  occipital 
bone  may  at  times  be  the  first  source  of  trouble.     We 
think,  however,  that  in  tetanus  infantum  different  cases 
may  have  widely  different  causes.     When  wc  remember 
the  favorable  development  of  the  infant's  nervous  economy 
toward  such  an  accident,  varying  doubtless  in  different 
individuals  within  wide  limits  of  susceptibility,  it  seems 
scarcely  probable  that  only  one  universal  cause  is  always 
operative.    Any  injury  or  trauma  should  rather  be  looked 
upon  as  a  possible  exciting  cause  and  endeavor  be  made 
to  remove  it.     Certainly  the  medical  treatment  of  this 
disorder  is  extremely  unsatisfactory. 


ARTIFICIAL  HYPNOTISM   IN   PHYSIOLOGY  AND  THERA- 
PEUTICS. 

The  so-called  mesmeric  sleep — artificial  or  induced  hyp- 
notism— although  it  can  scarcely  be  said  as  yet  to  have 
found  a  well-recognized  place  in  the  domain  of  either 
physiology  or  practical  medicine,  and  though  still  looked 
upon  with  disfavor  and  contempt  by  very  many  in  the 
profession,  is  being  made  the  subject  of  earnest  study — 
as  it  was  by  the  late  Dr.  Beard  in  this  country — by  sev- 
eral eminent  physiologists  in  England^and  on  the  Conti- 
nent. 

Dr.   Laugley,  of  London,  has  written  a  very  enter- 


taining and  scientific  article  on  the  subject  in  the  Pop^ 
ular  Science  Monthly  (October,  1884);  the  late  Pro- 
fessor  Las^gue,  of  Paris,  was  an  accomplished  hypnotist, 
devoted  much  attention  to  the  subject,  and  used  to  tuni 
it  to  account  in  the  treatment  of  his  hysterical  patients; 
Emile  Yung,  who  has  lately  written  a  very  entertaining 
book  on  "  Normal  and  Pathological  Sleep,"  has  a  long 
chapter  on  mesmerism,  in  which  he  details  the  advan- 
tages  which  may  be  derived  from  it  in  hysteria  ;  Charles 
Richer,  in  his  "Clinical  Studies  in  Hystero-Epilepsy," 
speaks  highly,  as  a  means  of  treatment,  of  "  Braidism" 
(so  named  because  Braid,  of  England,  in  1843,  was  the 
first  to  give  this  artificial  sleep  a  scientific  exposition); 
and  Heidenhain,  of  Breslau,  has  experimented  much  in 
hypnotism  and  written  much  about  it 

At  a  recent  meeting  of  the  French  Association  for  the 
Advancement  of  Sciences,  Dr.  Bernheim,  of  Nancy,  well- 
known  as  a  clinician  and  the  author  of  a  work  on  prac- 
tical medicine,  read  a  report  of  three  cases  of  chorea 
cured  by  what  he  calls  "the  hypnotic  suggestion."  He 
remarks  that  f*  suggestion "  in  the  hypnotic  state  may 
"  realize  "  (cause)  paralysis,  contraction,  anaesthesia,  and 
divers  functional  troubles,  and  that  it  is  natural  to  dfr 
mand  if  this  same  "  suggestion  "  may  not  in  certain  cases 
cause  such  functional  troubles  to  disappear.  Dr.  Bera- 
heim  affirms  that  for  many  years  he  has  obtained  a  great 
variety  of  excellent  therapeutic  effects,  and  often  sub- 
stantial cures  by  the  "  suggestive "  method,  "  which 
consists,  during  the  provoked  sleep,  in  affirming  the  dis- 
appearance of  the  different  subjective  symptoms  experi- 
enced by  the  patient." 

Drs.  Heurot  and  Voisin,  at  the  same  meeting,  related 
cases  in  their  practice  where  they  had  derived  benefit 
from  "suggestion."  Voisin's  patient  was  a  female,  "de- 
bauched, coarse,  and  lazy."  He  utilized  the  hypnotic  sleep 
"to  calm  this  hyper-excitation,  mental  and  sensorial!" 
During  the  mesmeric  sleep — which  he  kept  up  for  ftom 
ten  to  twelve  hours  a  day — he  improved  the  opportunity 
'  to  suggest  to  the  patient  "  ideas  of  obedience,  of  submis 
sion,  of  decency,  and  exhorted  her  to  useful  labor."  He 
also  encouraged  her  to  learn  by  heart  entire  pages  from 
some  moral  book.  "  A  complete  transformation  was  ef- 
fected in  several  months  ! " 

Whether  or  no,  in  accordance  with  the  above  example* 
it  shall  yet  be  found  that  the  best  way  to  reform  the  im- 
moral and  criminal  class  is  to  hypnotize  them  and  "  sug- 
gest*' morality,  subordination,  and  decency,  remains  for 
future  sociological  experimenters  to  decide. 

Dr.  J.  N.  Langley,  in  the  Popular  Science  Monthly^' 
who  thinks  that  "  there  is  no  doubt  that  mesmerism  may 
help  and  sometimes  cure  persons  suffering  from  certain 
diseases  of  the  nervous  system,"  ably  treats  the  subject 
from  a  physiological  standpoint.  He  thinks  that  "as 
disease  may  be  the  result  of  either  over-activity  or  of 
under-activity  of  any  part  of  the  central  nervous  system, 
it  is  reasonable  to  suppose  that  a  beneficial  effect  will 
follow  the  employment  of  a  method  which  allows  us  to 
diminish  or  increase  this  activity  at  will.**  This  is,  he 
thinks,  a  side  of  the  question  "  which  is  of  the  greatest 
interest  both  to  physicians  and  to  physiologists,  since  it 
bears  directly  upon  the  problem  of  the  influence  of  the 

1  Popular  Science  Monthly,  October,  1884:  Tbe  Phyiiolo«ical  Aspect  of  Met 


December  6,  1884.] 


THE   MEDICAL  RECORD. 


633 


nervous  system  on  nutrition.  "  There  is  good  reason  to 
believe  that,  by  directing  attention  strongly  to  any  par- 
ticular part  of  the  body,  the  nutritive  state  of  that  part 
of  the  body  naay  be  altered.  The  determination  of  the 
actual  way  in  which  this  is  brought  about  is  full  of  difficul- 
ties, but  the  following  way  is,  at  least,  theoretically  pos- 
sible. It  may  be  that  the  nerve-centres  connected  with 
the  tissue  in  question  are  made  unusually  active,  and 
that  they  send  out  nerve-impulses  of  a  trophic  nature, 
that  is,  impulses  which  directly  control  the  nutrition  of 
the  tissues.  The  alteration  in  the  tissue  caused  by 
its  changed  nutritive  state — its  changed  metabolism — 
raay  conceivably  be  beneficial  or  detrimental  to  the  whole 
organism  ;  it  may  give  rise  to  a  diseased  state,  or  get  rid 
of  an  existing  one." 

This  writer's  explanations  of  the  phenomena  of  hypnot- 
ism are  summed  up  in  the  following  propositions  :  "  The 
primary  condition  of  mesmerism  is  an  inhibition  of  a  par- 
ticular mode  of  activity  of  the  cortex  of  the  brain,  in 
consequence  of  which  the  will  can  no  longer  be  effective. 
This  inhibition  may  be  brought  about  by  nervous  im- 
pulses coming  from  certain  sensory  nerves,  as  those  of 
sight,  touch,  and  hearing.    It  may  also  be  brought  about 
by  impulses  or  changes  arising  in  the  cortex  itself.     The 
inhibited  cortex,  and  probably  also  inhibited  lower  centres 
of  the  brain,  send  out  inhibitory  impulses  to  all  other 
parts  of  the  central  nervous  system,  so  that  the  mes- 
merized male  or  female  gradually  passes  into  a  state  of 
torpor  or  even  of  complete  anaesthesia.    The  phenomena 
of  the  excitable  stage  of  mesmerism  are  proximately  de- 
termined by  the   possibility  of  exciting  any   particular 
centre  alone,  without  exciting  at  the  same  time  other 
centres,  by  which  its  activity  is  normally  controlled.     In 
lower  animals  this  stage  is  less  marked,  in  consequence 
•   of  a  greater  interdependence  of  the  various  parts  of  the 
central  nervous  system. 

^eiws  at  tlije  WSizzU. 

M.  Pasteur  is  going  to  Rio  Janeiro  to  study  yellow 
fever. 

Our  National  Sanitary  Patrol. — ^The  Revenue 
Marine,  consisting  of  38  vessels  and  950  officers  and  men, 
covers  the  entire  coast  of  our  country  and  acts  when 
needed  as  a  sanitary  patrol. 

Epidemic  of  Hybrophobia  in  Vienna. — A  cable  re- 
port, under  date  of  November  26th,  states  that  a  veritable 
epidemic  of  hydrophobia  is  prevailing  in  Vienna,  Already 
eighty  cases  have  been  reported. 

Epii>kmic  Dysentery. — The  daily  papers  have  had 
much  to  say  regarding  a  fatal  epidemic  disease  which  has 
been  attacking  the  inhabitants  of  Eastern  Kentucky  and 
Western  Virginia.  We  are  informed  that  the  disease  is  a 
dysentery  caused  by  drought,  filth,  and  bad  food.  The 
stories  regarding  it  have  been  much  exaggerated. 

A  Hermaphrodite. — A  person  calling  herself  by  the 
ambiguous  name  of  Madame  Duplex  de  Balzac,  informs 
the  profession  that  she  (or  he)  Jhas  just  arrived  from 
Europe  and  **  intends  to  exhibit  herself  (or  himself)  before 
any  person  who  is  anxious  to  enlighten  himself  on  natural 
science."  Dr.  William  T.  Lusk  certifies  that  Mrs. 
Duplex    de  Balzac  is  an  example  of  hypospadias.     The 


generation  organs  are  those  of  a  male,  but  the  general 
habit  of  the  individual  (and  it  is  this  which  makes  the 
case  an  interesting  one),  is  of  the  feminine  type.  The 
bones  are  small,  the  wrists  and  ankles  are  slender,  the 
breasts,  the  hair,  the  complexion,  and  the  voice  are  those 
of  a  female.  Dr.  William  M.  Polk  states  that  it  is  a  case 
of  true  hermaphroditism. 

Money  for  Physicians'  Widows. — The  forty-second 
annual  meeting  of  the  Society  for  the  Relief  of  Widows 
and  Orphans  of  Medical  Men,  was  held  last  week,  and 
the  following  officers  were  elected  by  ballot :  President 
—Dr.  S.  S.  Purple ;  Vice-Presidents— Drs.  J.  L.  Vander- 
voort,  J.  W.  Warner,  T.  F.  Coch ;  Treasurer— Dx,  John 
H.  Hinton  ;  Board  of  Managers — Drs.  G.  M.  Smith, 
T.  C.  Finnell,  Afred  C.  Post,  John  J.  Mulhan,  Willard 
Parker,  Isaac  E.  Taylor,  and  W.  T.  White.  The  report 
for  the  year  ending  September  12  th,  showed  that  the 
actual  expenses  of  maintaining  the  Society  were  but 
$47.85,  while  the  total  receipts  from  various  sources  were 
$50,016.33.  There  was  paid  for  annuities  to  14  widows  ' 
and  8  orphan  children  $4,252.50,  and  invested  in  bonds 
and  mortgages  $37,000.  The  total  assets  of  the  Society 
on  September  19th,  were  $143,447.96. 

Suicide  of  an  Insane  Physician. — A  Danish  adven- 
turer calling  himself  Dr.  F.  De  Castro,  committed  sui- 
cide in  Newark  last  week.  His  last  will,  dated  February 
12,  1883,  read  as  follows  :  **  After  death  I  request  that 
my  body  shall  be  given  to  the  Chicago  Medical  College, 
or  any  medical  college  in  the  city  of  Chicago,  upon  the 
following  conditions  :  After  the  body  has  been  serving  its 
medical  purpose  for  science,  the  entire  skeleton  be  placed 
in  the  museum  with  the  following  inscription  on  the  brow 
of  the  skull :  *  This  is  the  skeleton  of  F.  De  Castro,  the 
great  traveller  and  linguist,  who  died  a  martyr  for  those 
he  loved  so  well.*  If  the  Chicago  colleges  will  not  ac- 
cept the  body,  any  medical  college  in  the  city  of  New 
York  which  will  comply  with  my  request  may  take  charge 
of  it." 

The  President's  Message. — In  his  annual  message, 
referring  to  the  subject  of  cholera  President  Arthur 
states  that,  pursuant  to  his  proclamation,  the  Secretary  of 
the  Treasury  prohibited  the  importation  of  rags  and  the 
admission  of  baggfige  of  immigrants  and  of  travellers  ar- 
riving from  infected  quarters.  '^  Lest  this  course  may 
have  been  without  strict  warrant  of  law,  I  approve  the 
recommendation  of  the  present  Secretary,  that  Con- 
gress take  action  in  the  premises,  and  I  also  recommend 
the  immediate  adoption  of  such  measures  as  will  be  likely 
to  ward  off  the  dreaded  epidemic  and  to  mitigate  its 
severity  in  case  it  shall,  unhappily,  extend  to  our 
shores." 

Regarding  the  Army  Medical  Museum,  he  says  :  "  Dur- 
ing the  past  session  of  Congress  a  bill  to  provide  a  suita- 
ble fireproof  building  for  the  Army  Medical  Museum  and 
the  library  of  the  Surgeon- General's  office  received  the 
approval  of  the  Senate.  A  similar  bill,  reported  favor- 
ably to  the  House  of  Representatives  by  one  of  its  com- 
mittees, is  still  pending  before  that  body.  It  is  hoped 
that  during  the  coming  session  the  measure  may  become 
a  law,  and  that  thereafter  immediate  steps  may  be  taken 
to  secure  a  place  of  safe  deposit  for  these  valuable  col- 
lections, now  in  a  state  of  insecurity." 


634 


THE   MEDICAL   RECORD. 


[December  6, 1884 


NEW  YORK   NEUROLOGICAL   SOCIETY. 

Stated  Meeting y  November  11,  1884. 
W.  J.  Morton,  M.D.,  President,  in  the  Chair. 

SPINAL  CONCUSSION  AND  THE   NATURE  OF  ITS   SEQUELiG. 

Dr.  C.  L.  Dana  read  a  paper  on  this  subject  (see  p.  617). 

Dr.  W.  a.  Hammond  said :  I  agree  with  Dr.  Dana  in 
the  view  that  there  is  such  a  thing  as  concussion  of  the 
spinal  cord.  I  agree  with  him  further  in  the  doctrine 
that  it  is  difficult  for  us  to  tell  by  the  symptoms  what  the 
exact  nature  of  the  injury  is  that  the  patient  has  suffered. 
But  this  fact,  I  think,  remains,  that  there  is  some  injury 
which  the  spinal  cord  is  capable  of  suffering,  which  is  not 
of  such  a  serious  character  as  to  cause  death,  and  which 
is  not  accompanied  by  any  injury  to  the  bones,  or  to  the 
muscles  or  ligaments.    That  after  all  is  the  practical  point. 

Dr.  Hammond  then  related  the  history  of  two  cases  of 
spinal  concussion  in  which  he  had  been  called  as  an  expert. 
The  first  patient  suffered  from  muscular  weakness,  spinal 
pains,  severe  general  nervous  symptoms,  and  walked 
with  a  peculiar  paralytic  gait.  There  was  no  positive 
evidence  of  organic  disease  of  the  spinal  cord.  He  rc- 
'ceived  large  damages,  but  he  still,  twenty  years  later, 
suffers  from  his  trouble.  The  second  case,  of  a  somewhat 
similar  character,  made  a  better  recovery,  but  still  walks 
with  a  cane.  Dr.  Hammond  thought  that  this  patient 
suffered  from  some  organic  disease  of  the  cord. 

The  speaker  referred  to  the  first  case  which  occurred 
in  this  country  in  which  a  post-mortem  was  made.  The 
patient  was  a  physician,  who  fell  on  the  ice  and  suffered 
from  the  symptoms  of  antero-lateral  sclerosis.  On  post- 
mortem, sclerotic  patches  were  found  throughout  the 
spinal  cord.  I  think  traumatism  may  give  rise  to  spinal 
affections  without  there  being  any  palpable  lesion  of  the 
soft  parts,  or  of  the  bony  structures,  or  the  ligaments. 

Only  a  few  days  ago  I  was  called  to  the  upper  part  of 
the  city  to  see  the  case  of  a  woman  who  had  fallen 
through  a  dumb-waiter,  a  fire-escape,  or  something  of 
that  sort,  which  barely  allowed  her  to  pass  in  a  doubled- 
up  form.  She  fell  a  distance  of  thirty-five  feet,  by  meas- 
urement, into  ihe  cellar,  striking  on  her  buttocks  upon 
the  hard  ground.  There  was  no  fracture.  Three  months 
after  the  occurrence  of  the  injury  I  saw  her.  She  was 
still  suffering  from  paraplegia  and  incontinence  of  urine, 
and  paralysis.  Hypochondriasis  and  hysteria  had  also 
developed  to  an  extreme  degree.  Yet  she  is  rapidly  re- 
covering. I  do  not  think  there  was  any  hemorrhage  in 
her  case,  because  I  do  not  think  hemorrhages  of  the 
spinal  cord  are  recovered  from.  She  suffered  not  only 
from  motor  troubles,  but  from  sensory  disturbances  like- 
wise ;  also  from  atrophy  of  her  limbs,  showing  that  the 
injury  involved  the  whole  segment  of  the  cord,  both  the 
sensory  and  motor  parts.  Yet  she  has  recovered,  and  I  do 
not  believe,  therefore,  that  in  her  case  there  was  any  de- 
struction of  the  cord.  I  cannot  conceive  that  there 
could  have  been  anything  else  than  a  concussion. 

Now,  I  would  like  to  know  what  it  is  that  happens 
sometimes  when  patients  lift  heavy  weights  and  they  feel 
something  give  way  in  the  back,  and  after  that  they  lose 
the  use  of  their  limbs,  gradually  waste  away,  and  become 
paralyzed.  I  have  seen  such  cases.  I  remember  one 
which  came  under  my  observation  some  years  ago,  where 
the  patient,  endeavoring  to  lift  a  heavy  window,  got  his 
hand  in  place  and  lifted  with  all  his  might,  and  suddenly 
felt  something  give  way  in  his  side.  There  was  tio  in- 
jury there  that  could  be  detected  by  an  examination  ; 
there  was  no  fracture  ;  no  dislocation.  And  yet  that  pa- 
tient gradually  lost  the  use  of  his  legs.  What  was  that  ? 
Probably  a  rupture  of  some  of  the  fibres  of  the  cord  or 
of  the  membranes  of  the  cord ;  certainly  an  injury  to  the 
cord  and  not  of -the  bony  structures  about  it. 

I  cannot  conceive  of  the  possibility  of  getting  rid  of 
these  facts,  that  the  spinal  cord  is  capable  of  suffering 
injury,  without  there  being  any  detectable  lesion  of  the 
soft  parts,  or  of  the  bones,  or  of  the  ligaments,  or  inter- 


vertebral substance,  and  that  the  trouble  inside  of  the 
spinal  canal  involves  the  spinal  cord. 

Dr.  Corning  related  the  history  of  a  case  in  which 
partial  impotency  persisted  long  after  the  accident,  and 
in  which  there  were  marked  suicidal  tendencies.  There 
was  not  a  trace  of  external  injury. 

Dr.  Rockwell  considered  that  organic  or  structural 
conditions  seldom  followed  concussion  of  the  spinal 
cord.  Notwithstanding  the  fact  that  at  the  present  time 
he  had  under  his  care  a  young  person  who  was  suffering 
from  typical  myelitis,  ascribed  to  a  severe  fall  followed 
at  once  by  incomplete  paraplegia,  which  had  gone  on  to 
complete  paraplegia,  it  seemed  almost  incredible  to 
him  that  a  person  could  have  severe  concussion  of  the 
spine  without  the  cerebro-spinal  system  in  its  entirety 
being  involved.  In  concussion  there  seldom  could  be  a 
rupture  of  the  vessels  or  nerve-fibres  without  causing 
death.  The  majority  of  cases  of  concussion  that  had 
come  under  his  observation  had  presented  symptoms  as 
manifold  almost  as  those  of  neurasthenia.  The  progno- 
sis was  generally  good,  and  the  best  remedy  time.  The 
concussion  that  follows  the  blow  of  a  bullet  was  fre- 
quently observed  during  our  war. 

Dr.  Hammond  added  a  case  of  railway  injury,  in  which 
there  was  no  lesion  whatever  of  the  external  parts  appar- 
ent;  but  there  were  ocular  disturbances  (which  he  thinb 
are  rare,  as  Dr.  Dana  says).  The  patient  had  double 
vision  ;  congestive  disks  ;  bird  vision  ;  and  suffered  from 
the  symptoms  of  neuro-retinitis,  but  they  eventually  dis- 
appeared.  He  had  marked  paralysis  of  the  nerve  on  one 
side.  He  was  injured  in  the  upper  part  of  the  cord ; 
suffered  from  loss  of  power  in  his  arms  and  legs.  Had 
head  symptoms,  was  hypochondriacal  and  hysterical  He 
recovered  a  very  large  sum  from  the  railway  company. 

Dr.  Weber  remarked  that  from  what  he  had  seen  and 
read  upon  the  subject,  it  seemed  to  him  that  Page  was 
certainly  stealing  a  march  upon  Erichsen  with  regard  to 
the  views  which  Erichsen  entertains.  As  I  said  in  a 
paper  read  before  this  Society  upon  another  subject,  the 
more  we  shall  get  into  the  habit  of  including  a  thorough 
examination  of  the  cord  and  its  meninges  in  post-morteno, 
the  more  our  knowledge  upon  the  demonstrable  lesions 
will  increase,  and  the  less  we  shall  hear  in  the  course  of 
time  of  concussion  of  the  spine.  I  do  not  mean  to  say 
that  there  is  no  such  thing  as  concussion  of  the  spine,  but 
I  believe  that  a  good  many  cases  which  are  considered 
as  such  are  not  (in  spite  of  the  symptoms  pointing  that 
way)  dependent  upon  concussion  of  the  spine,  bat 
upon  concussion  of  the  brain.  Now,  the  case  which  has 
been  related  by  Dr.  Hammond,  of  the  woman  falling 
down  a  dumb-waiter,  thirty-five  feet,  and  striking  upon 
her  buttocks — taking  it  for  granted  that  there  was  a  com- 
plete absence  of  all  injury  to  the  soft  parts  and  to  the 
ligaments  and  bones,  as  Dr.  Hammond  stated — is  a  case 
more  of  concussion  of  the  brain  than  of  concussion  of 
the  spine. 

Dr.  Hammond  :  To  this  I  can  only  say,  that  there 
was  no  cerebral  symptom — that  was  my  understanding-^ 
in  the  early  part  of  the  disease. 

Dr.  Weber  :   There  may  have  been,  though.   .' 

Dr.  Hammond  :  I  understand  not  She  never  lost 
consciousness  for  a  moment.  I  cannot  conceive  of  con- 
cussion of  the  brain  without  loss  of  consciousness. 

Dr.  Weber  :  In  an  abstract  of  a  large  number  of 
papers  that  I  read  recently,  in  a  volume  of  Virchow- 
Hirsch's  /ahresberUht,  I  found  that  most  of  the  lead- 
ing physicians  abroad  believe  that  many  cases  of  so-called 
concussion  of  the  spine,  without  any  injury  to  the  soft 
parts  or  the  bones,  really  depend  upon  concussion  of  the 
brain.  Some  years  ago  1  saw,  at  the  St.  Francis  Hospi- 
tal, a  case  precisely  like  the  one  related  by  Dr.  Ham- 
mond. It  concerned  a  young  man  who  had  been  trying, 
on  a  wager  with  some  other  man,  to  lift  heavier  and 
heavier  weights.  While  still  straining  he  suddenly  felt 
something  give  way  in  his  back.  He  fell  down  and  lost 
the  use  of  his  limbs.     When  I  saw  him,  two  weeks  after  the 


December  6,  1884.J 


THE   MEDICAL  RECORD. 


63: 


accident,  there  was  paraplegia  of  the  lower  limbs  and  a 
paralytic  condition  of  his  bladder.  He  remained  in  the 
hospital  for  some  time,  and  failing  to  improve,  he  was  at 
.  leDgth  discharged.  I  look  upon  this  case  as  one  of  apo- 
plexy of  the  spinal  cord. 

Dr.  Roberts  viewed  the  diversity  of  opinions  as  show- 
ing a  manifest  want  of  conception  of  fundamental  ideas 
in  regard  to  the  subject.     He  considered  the  problem 
one  ot  physics  ;  dealing  with  a  material  object,  and  the 
forces  acting  upon  it     Among  the  queries  propounded 
occurs  this  one  :  Is  it  possible  for  the  spinal  cord  to  be- 
come concussed  without  injuring  any  of  the  hard  parts 
of  the  vertebrae  ?    Now,  what  is  a  traumatism  ?    What  is 
concussion  ?     The  effect  of  blows  upon  hard,  and  upon 
soft  or  elastic  substances,  is  very  different.    And  we  have 
every  reason  for  believing  that  this  eflfect  differs  upon  the 
hard  and  soft  parts  of  the  human  body  ;  for  the  effects 
considered  from  the  physical  standpoint  are  the  same,  so 
far  as  the  mechanical  effects  are  concerned.     Vibratory 
impulses,  we  find,  are  conveyed  with  much  greater  facility 
along  a  hard  wooden  beam  than  they  are  through  the  at- 
mosphere.    Now,  if  we  saw  the  beam  in  two  and  inter- 
pose an  elastic  buffer,  it  will  be  found  that  the  sound  will 
not  be  transmitted  ;  a  physical  barrier  to  the  transmission 
of  these  impulses  has  been  interposed.     I  may  summarize 
two  or  three  principles  which  underlie  this  problem  by 
stating  that  the  harder  the  substance  and  the  more  direct 
its  continuity  the  greater  is  its  conductivity  to  jars,  to  vi- 
bratory impulses,  to  injuries.     When  a  human  being  is 
thrown  from  a  vehicle  and  strikes  upon  the  ground,  the 
force  with  which  he  is  carried  is   represented  by  the 
rapidity  with  which  the  body  is  moving  and  its  bulk. 
Now,  it  took  a  certain  amount  of  force  to  set  his  body  in 
motion,  and  it  would  take  an  equivalent  amount  of  force 
to  arrest  that   motion.     When  he  strikes  against   the 
ground  this  motion  is  arrested;  he  must  meet  with  a 
force  equivalent  to  that  which  is  represented  by  his  mo- 
mentum.    The  force  is  thus  annihilated  and  is  expended 
upon  the  jarring.     How  can   these  vibratory  impulses 
affect  the  individual?    We  must  examine  the  hard  and 
soft  parts,  and  the  attitude  of  tl\e  individual,  and  from 
our  examination  of  inert  physical  substances,  we  have 
reason  to  go  at  once  to  the  bones  for  the  channel  through 
which  these  vibratory  impulses  can  most  readily  be  con- 
veyed.    The  attitude  of  the  patient  at  the  time  the  blow 
is  received  is  an  important  factor  in  determining  the 
probable  amount  of  injury.     If  the  skeleton  is  erect  and 
the  patient  is  thrown  forcibly  upon  his  feet  in  the  erect 
attitude,  the  resulting  injury  will  be  much  greater  than  it 
would  if  he  were  in  a  crouched  position.     But  then,  in 
this  steoping  attitude,  the  limits  of  the  elasticity  of  his 
muscles,  and  the  limits  of  the  elasticity  of  the  flexure, 
may  be  exceeded  when  the  blow  is  so  severe  as  to  over- 
come /the  power  of  the  muscles  to  maintain  this  protect 
tive  attitude.     Another  important  factor  to  be  consid- 
ered is  :   whether  the  patient  be  fat  or  lean,  for  we  are 
dealing  with  a  physical  problem.     Elastic  substances  are 
always  the  materials  with  which  we  annihilate  or  absorb 
vibratory    impulses.     Strike  a  living  skeleton,  such  as 
you  see  in  our  museums,  forcibly  upon  the  breast,  and 
you    produce   a   shock   that    may  result    disastrously ; 
whereas  a  blow  upon  a  well-developed  pectoral  muscle 
is  received  with  impunity. 

Dr.  ORi«ME  Hammond  did  not  think  that  there  was 
any  question  at  all  that  cases  of  congestion  of  the  spine 
and  symptoms  referable  to  the  cord  alone  did  appear  after 
the  spine  had  been  in  receipt  of  an  injury.  He  thought 
the  question  of  the  greatest  importance  was :  What  is  the 
nature  of  the  trouble  with  the  spine  ?  whether  it  is  a 
morbid  change  which  goes  on  progressively,  or  whether 
it  is  simply  functional. 

Dr.  W,  O.  Moore  stated  that  there  were  two  classes 
of  cases  met  with  in  ophthalmic  practice.  The  first  is 
that  which  me  meet  with  merely  upon  the  receipt  of  an 
injury  to  the  spinal  cord,  viz.,  ca<ies  in  which  there  was 
an  increase  in  the  circulation  of  the  optic  papillae,  and 


cases  where  there  was  decided  neuro-retinitis.  In  one 
case  there  was  atrophy  of  the  optic  nerve.  Whether 
concussion  took  place  as  claimed  by  the  history  of  the 
patient  he  could  not  decide,  but  two  cases  in  his  history 
book  give  decided  evidence  that  concussion  of  the  spine 
did  occur.  In  one  case  the  patient  fell  from  the  second 
story,  striking  mostly  upon  his  feet  and  buttocks.  His 
general  health  was  at  once  affected,  and  he  Aras  not  able 
to  attend  to  business  thereafter.  He  had  more  or  less 
neurasthenic  symptoms.  Two  years  later  failure  of  vision 
was  noticed,  from  ordinary  atrophy  of  the  optic  nerve. 
Color-blindness  then  appeared,  first  for  red,  then  for 
green,  then  for  yellow  and  blue,  and  then  it  was  entirely 
gone.  After  ten  years'  failure  of  vision  he  is  now  totally 
blind,  and  has  no  symptoms  of  locomotor  ataxia  or  any- 
thing of  that  sort.  In  the  other  case,  the  patient  was 
thrown  from  his  seat  on  a  wagon  and  fell  in  a  heap,  with- 
out striking  any  particular  part  of  the  head.  Atrophy  of 
the  optic  nerve  took  place  on  one  side.  The  case  was 
under  observation  about  two  years,  until  finally  the 
atrophy  was  complete  and  there  was  total  blindness  of 
that  eye.  In  the  other  eye  he  did  have  for  several  days, 
two  or  three  weeks  after  the  injury,  a  flushing  of  the  optic  , 
disk.  At  one  time  it  was  feared  that  it  would  likewise 
become  atrophied.  The  last  case  was  considered  by 
some  eye  men  rather  a  case  of  concussion  of  the  optic 
nerve.  That  there  is  a  connection  between  the  symptoms 
of  the  spinal  disease  and  the  eye,  there  is  no  doubt.  We 
see  it  causing  atrophy  of  the  pupil,  and  later  on  contrac- 
tion of  the  pupil.  He  thinks  there  is  no  doubt  a  connec- 
tion between  the  sympathetic  and  medullary  fibres  which 
go  to  the  pupil.  In  these  cases  there  was  no  direct  blow  to 
the  eye  nor  head,  and  no  laceration  or  contusion  of  any 
soft  parts. 

Dr.  Dana  considered  Dr.  Moore's  cases  extremely 
interesting,  because  they  contradict  entirely  the  very 
positive  statements  of  Mr.  Page  in  his  work  on  "  Injuries 
to  the  Spine."  He  then  read  the  following  letter  from 
Dr.  Allan  McLane  Hamilton  regarding  this  subject : 

"While  I  have  been  satisfied,  from  a  very  varied  experi- 
eitce  in  court  and  elsewhere,  that  the  vast  majority  of 
those  who  claim  compensation  for  railway  injuries  are 
malingerers  and  impostors,  I  still  find  that  nervous  shock 
is  quite  apt  to  develop  a  *  railway  hysteria'  in  some, 
which  is  in  every  sense  a  real  disease,  and  is  due  to  actual 
physical  disease,  and  in  others  to  the  development  of  a 
morbid  expectant  attention.  It  is  unnecessary  to  adopt 
the  extreme  opinion  of  either  Erichsen  or  Page.  There 
is  in  sixty  per  cent,  of  the  cases  an  intermediate  condition 
in  which  subjective  symptoms  are  the  only  ones.  In 
some  of  these  cases  the  hemiansesthesia,  lately  described 
by  Putnam,  may  be  detected  by  abstract  tests.  In  others 
we  are  furnished  with  vague  yet  unmistakable  disorders 
of  a  functional  yet  serious  nature.  I  strongly  disprove  of 
the  injustice  of  juries  who  manifest  an  assinine  disregard 
of  scientific  proof,  and  award  enormous  damages  because 
of  prejudice  against  corporations,  simply  upon  the  story 
of  the  plaintiff.  On  the  other  hand,  there  are  cases  turned 
out  of  court  when  some  award  should  be  made.  I  do 
believe  that  in  the  great  number  of  well-established  cases 
of  railway  hysteria,  that  moderate  verdicts  should  be  ren- 
dered, just  as  they  are  in  punitive  libel  cases  when  the 
peace  of  mind  has  been  hurt.  In  the  majority  of  cases 
no  speculative  damages  should  be  allowed  upon  a  simple 
personal  relation  of  symptom." 

Dr.  J.  G.  Johnson,  of  Brooklyn,  asked  Dr.  Moore 
whether,  in  the  case  he  mentioned,  there  was  a  connect- 
ing train  of  symptoms  that  showed  that  the  blow  did  the 
injury. 

Dr.  Moore  replied  that  the  man  who  fell  from  the 
wagon  was  seen  thirty-six  hours  after  the  injury.  He 
had  failure  of  vision  from  the  very  beginning;  in  that  case 
he  had  flushing  of  the  optic  nerve,  and  decided  symptoms 
of  neuro-retinitis.  This  gave  way  after  a  period  of  two 
years,  and  atrophy  developed.  In  the  other  case,  where 
the  patient  fell  from  one  story  to  the  other,  the  patient 


636 


THE   MEDICAL  RECORD. 


[December  6, 1X84. 


had  double  optic  atrophy,  which  of  course  may  have 
arisen  from  other  causes.  As  far  as  I  can  get  the  evi- 
dence from  Dublin,  it  was  a  decided  case  of  concussion. 
As  he  remembered  the  case  it  began  some  years  after  the 
accident 

Dr,  Johnson  asked  if  there  was  an  early  history  of  the 
case? 

Dr.  Moore  said  there  was  not.  It  came  on  some 
years  after  this  trouble.  He  had  no  evidence  of  locomotor 
ataxia. 

Dr.  Harwood  remarked  that,  out  of  a  number  of 
sufferers  from  railway  accidents,  he  recalled  two  cases 
of  spinal  concussion.  He  advised  the  patients  and  the 
corporation  to  settle  amicably.  But  his  advice  was  not 
taken  in  either  of  the  two  cases,  and  they  finally  went  to 
trial.  His  view  was  sustained  by  the  jury,  and  a  ver- 
dict was  secured  for  the  plaintiff ;  but  what  is  very  un- 
usual in  these  cases,  as  he  had  observed  them  in  suits  that 
had  been  brought,  these  patients  ultimately  died  from 
the  results  of  their  injuries. 

Dr.  Adams  observed  that  most  of  the  cases  that  showed 
any  injury  after  a  concussion  generally  showed  it  in  the 
lower  extremities.  Many  cases  of  Pott's  disease  were 
recognized  by  most  authorities  to  be  caused  by  concus- 
sion. It  would  appear  that  the  milder  injuries  caused 
ordinary  concussion  of  the  spine,  and  more  severe  ones 
Pott's  disease. 

Dr.  J.  G.  Johnson  :  I  only  wish  to  say  that  a  fact  which 
would  militate  against  any  such  hypothesis  as  that  is,  that 
in  the  case  of  vertebral  caries,  which,  according  to  this 
theory,  is  supposed  to  result  from  more  severe  injuries, 
we  have  none  of  the  symptoms  of  spinal  concussion. 
I  merely  want  to  ask  the  neurologists  one  question,  and 
that  is,  if  they  have  ever  seen  a  case  of  spinal  concussion 
in  a  railway  employee  (who  takes  the  risk  of  the  convey- 
ance) without  the  physical  symptoms  showing  either 
meningitis  or  myelitis?  These  anomalous  symptoms, 
which  are  laid  down  by  Erichsen  with  such  fluency  of 
language,  I  have  never  seen  in  my  twenty-five  years'  ex- 
perience as  a  railroad  surgeon.  I  have  never  seen  a 
single  railway  employee  have  them.  And  for  this  reasons 
Dollars  and  cents  do  not  enter  into  the  consideration  of 
the  railway  employee.  He  has  every  inducement  to  get 
well ;  he  has  his  family  to  support ;  if  he  does  not  get  well 
in  a  reasonable  time  he  goes  out,  and  somebody  else  takes 
his  place.  On  the  other  hand,  the  man  who  has  been  on 
a  railway  train,  who  has  a  good  shaking  up  and  a  terrific 
scare,  has  no  object  in  getting  well.  The  company  has 
got  to  pay  him  roundly ;  it  has  to  pay  him  for  his  loss  of 
time ;  it  has  to  pay  him  for  his  suffering,  both  mental  and 
physical ;  it  has  to  pay  his  surgeon  also  ;  his  surgeon  has 
an  unknown  quantity  to  handle ;  he  has  something  to 
treat  that  the  patient  does  not  understand.  If  the  patient 
has  a  broken  leg  he  knows  what  he  has  got,  and  the  doctor 
cannot  come  in  and  discuss  spmal  concussion  symptoms, 
and  all  that.  He  has  seen  broken  legs  before ;  has  had 
cold  extremities,  vomiting,  exhaustion,  and  so  on  ;  but 
he  has  not  had  the  scare  of  a  doctor  coming  in,  feeling 
up  and  down  his  back  to  see  whether  it  pains  him,  and 
asking  him  whether  he  can  stand  on  his  legs,  and  going 
through  all  those  symptoms,  that  unknown  quantity  which 
they  J  know  so  well  to  do.  He  has  not  had  some 
confrere  to  come  in  and  suggest  some  more  doubts.  The 
doctor,  in  a  good  many  cases,  is  hungry,  and  the  big  cor- 
poration may  pay  his  bill.  He  has  to  examine  that  back 
often  ;  he  has  to  find  out  just  what  these  doubtful  things 
mean  ;  and  the  patient,  having  it  iterated,  and  reiterated, 
and  reiterated  again,  begins  to  believe  himself  that  there 
is  something  terrible  the  matter  with  him.  He  does  not 
dare  to  go  out  and  take  a  little  fresh  air  and  exercise 
(which,  as  my  friend,  Dr.  Hammond,  says,  is  the  best 
thing  to  restore  the  nerves),  because  a  railway  man  might 
be  around  and  spy  him  using  his  limbs.  He  gets  morose, 
and  has  no  object  to  get  well,  because  that  suit  is  not 
settled.  He  begins  to  have  some  motor  disturbances  ; 
he  has  these  profuse  sweats,  etc.     When   you  come  to 


take  that  kind  of  disturbance — of  expecting  to  recover 
from  the  company — out  of  the  question,  they  get  well 
very  frequently  with  indecent  haste. 

In  regard  to  the  claim  of  destruction  of  the  virile 
power,  which  has  been  alluded  to  here  by  one  of  the 
speakers  this  evening,  that  is  one  of  the  most  common 
allegations  that  have  been  made  in  these  cases.  I  re- 
viewed that  point  in  a  paper  on  "  Railroad  Injuries,"  read 
before  the  Medico-Legal  Society. 

I  think  there  is  no  doubt  that  serious  lesions  of  the 
spine  and  spinal  cord  do  occur  as  the  result  of  railway 
concussions.  We  have  also  mingled  with  it  a  large 
variety  of  other  symptoms.  When  a  train  is  suddenly 
stopped,  the  patient  is  violently  thrown  backward  and 
forward,  shaking  up  all  the  viscera,  and  the  whole  sym- 
pathetic nervous  system,  and  the  other  organs  suffer. 
Added  to  that  this  terrific  fright  and  the  utter  helpless- 
ness  of  their  condition  and  the  effect  upon  the  mind  is 
something  which  is  severe.  But  with  all  that,  when  you 
come  to  consider  the  fact  of  compensation,  we  find  these 
cases  so  much  aggravated  that  I  do  not  think  any  physi- 
cian is  right  to  go  into  court  and  swear  that  the  patient 
has  disease  of  the  spine  unless  he  has  the  physical  symp. 
toms,  and  he  should  not  simply  rely  upon  the  statement 
of  the  patient,  who  is  interested  to  make  matters  as  bad 
as  he  can. 

I  saw  an  extremely  interesting  case  some  years  ago, 
which  was  the  result  of  a  railroad  disaster  on  the  New 
York  Central  Railroad.  The  patient,  a  lawyer  in  this 
city,  was  in  a  sleeping-car  when  it  was  derailed.  He  was 
thrown  down  an  embankment,  and  I  saw  him  the  next 
day  but  one.  He  was  in  such  a  condition  that  he  was  put 
on  a  return  train  and  came  to  Brooklyn.  There  were 
marked  contusions  of  his  shoulders,  abdomen,  breast, 
back,  and  hips,  showing  that  he  had  received  a  violent 
rolling  over.  Some  thirty-six  hours  from  the  time  of  his 
injury  his  limbs  began  to  fail  him.  He  could  walk  if  he 
was  watching  whejre  he  placed  his  foot.  If  he  walked, 
and  you  would  speak  to  him,  he  would  tumble  over. 
That  increased,  and  paralysis  of  sensation  followed,  un- 
til it  extended  up  as  far  as  the  ninth  dorsal  vertebra. 
There  was  no  shamming' about  it.  I  tried  electricity ;  I 
burned  his  legs  with  matches,  and  things  of  that  kind, 
which  he  would  not  have  been  able  to  stand  if  it  had 
been  felt  Dr.  Ranney  saw  the  patient  on  behalf  of  the 
New  York  Central  Railroad  Company.  The  case  was 
settled  at  about  twenty  thousand  dollars.  Dr.  Ranney 
based  his  claim  that  he  would  recover  on  the  fact  of  there 
being  no  wasting  of  the  hmbs.  I  at  that  time  held  the 
opinion  that  it  was  an  extravasation  of  the  blood  around 
the  substance  of  the  cord  ;  I  did  not  think  it  could  be  in 
the  pith,  from  the  fact  of  its  being  limited  to  the  nerves 
of  sensation  and  not  of  motion.  After  that  he  recovered 
entirely  and  thoroughly,  and  his  own  ph}'sician  and  my- 
self, who  examined  him  subsequently,  failed  to  find  any 
indication  of  any  physical  pain  whatever.  He  recovered 
in  about  six  months. 

There  is  a  point  of  interest  in  regard  to  these  spinal 
cases  alluded  to  by  Erb,  that  I  would  like  to  hear  about 
from  the  neurologists.  Men  long  connected  with  railway 
trains,  as  engineers,  after  a  while  lose  their  snap  ;  they 
don't  get  in  on  time.  Finally  they  show  a  complete 
nervous  break-down.  Erb  alluded  to  this  particularly. 
What  change  has  probably  taken  place  in  the  old  railway 
employees  where  there  is  this  nervous  break-down,  which 
shows  itself  by  a  lack  of  courage  and  nerve-power,  and 
by  gradual  failure  ?  These  cases  are  becoming  extremely 
interesting  in  Germany,  where  the  railway  employees  are 
allowed  damages,  just  the  same  as  passengers  on  trains, 
and  this  old,  worn-out  railway  nervous  system  is  being 
put  in  as  a  spinal  concussion. 

Dr.  Birdsall  thought  that  these  cases  were  a  good 
deal  rarer  than  the  general  impression  would  lead  one  to 
conclude.     The  prominence  which  the  work  of  Erichsen     | 
had  been  given,  had  led  people  to  look  for  effects  of 
spinal  concussion,  and  to  talk  about  them  a  good  deal 


December  6,  1884.] 


THE  MEDICAL  RECORD. 


637 


more  than  was  really  admissible  from  the  facts  of  obser- 
vation. 

He  had  been  led  to  conclude  that  many  patients 
had,  previous  to  their  concussion,  what  was  ordinarily 
termed  neurotic  or  neuropathic  constitution. 

It  had  been  stated  by  Dr.  Weber  that  many  of  these 
symptoms  were  cerebral.  He  thought  they  were  devel- 
oped, probably,  as  much  from  fright  as  from  concussion 
of  the  spinal  cord.  On  the  other  hand,  he  would  not  be 
understood  as  denying  the  existence  of  functional,  and 
perhaps  something  more  than  mere  functional,  disturb- 
ances of  the  cord  from  concussion.  There  was  a  good 
deal  of  difference  between  a  single  shock,  a  severe  shock 
due  to  railroad  accident,  and  the  continual  jarring  which 
went  on  in  a  man  in  the  cab  of  an  engine.  It  seemed 
to  him  that  in  a  healthy  person,  while  the  former  might 
be  readily  recovered  from,  the  latter,  even  of  a  more 
moderate  character,  would  prove  more  injurious,  and  he 
should  certainly  be  very  careful  about  classing  them  in 
the  same  group. 

Dr.  Johnson  said  the  length  of  time,  doubt,  and  un 
certainty  of  the  cases  are  important  elements  to  consider. 
As  far  as  a  surgeon  for  a  railroad  company  being  affected 
in  his  evidence  by  outside  influences  is  concerned,  he 
would  find  that  truth  was  the  first  essential;  he  would 
not  hold  his  appointment  for  twenty-four  hours  when  his 
company  was  satisfied  that  he  was  not  truthful.  When 
we  are  sent  to  investigate  a  case  on  behalf  of  the  cor- 
poration, we  make  as  thorough  and  as  exhaustive  an  ex- 
amination as  it  is  possible  with  the  knowledge  that  we 
have,  and  our  report  is  made  in  writing  and  goes  to  the 
company's  office,  with  everything  bearing  against  us  as 
well  as  bearing  for  us.  If  we  misrepresented  that  case, 
and  ^his  is  shown  in  evidence  in  court  when  the  case 
comes  to  trial,  it  shows  that  we  are  ignorant  or  dishonest, 
and  our  walking  tickets  are  prepared.  No  man  can 
hold  his  position  as  a  surgeon  for  a  company  who  is  not 
honest,  because  they  pay  by  dollars  and  cents  on  an 
opinion,  and  if  it  is  not  truthful  they  do  not  want  it. 

Luther  R.  Marsh,  Esq.,  said  he  was  bewildered  by 
the  medical  phraseology,  which  transcended  that  of  the 
legal  guild  in  the  magnitude  of  its  technology.     If  he 
were  to  ask  the  doctors  the  difference  between  "the 
whole  of  an  undivided  moiety,  and  the  moiety  of  an  un- 
divided whole  *'  they  would  understand  his  meaning,  but 
they  could  hardly  use  a  neurological  sentence  that  would 
not  send   him  to  his  dictionary.     When  quite  a  young 
man  he   had  written  an  article  for  a  local  newspaper, 
without  regard  to  sense,  but  simply  for  the  cadence  of 
the  sentences.     The  beginning  of  that  article,  which  the 
good  people  of  the  town  puzzled  over  with  their  glasses, 
ran  as  follows  :  "Pedaneous  are  the  gorgeous  geoponics 
of  saginated  hoplites."     But  while  his  big  words  were 
without  meaning,  theirs  were  not.     He  had  gleaned  from 
them  that  the  spinal  cord  was  certainly  capable  of  in- 
jury, without  any  necessary  harm  to  its  bony  or  other 
coverings.     The  paper  haid  seemed  to  him  eminently 
impartial,  steering  a  midway  course  between  what  the 
transportation  companies  might  call  the  extravagances  of 
Erichsen,  and  what  suitors  for  personal  injuries  might 
class  as  the  perversions  of  Page.     He  had  also  learned 
that  when  a  man  had  been  concussed,  as  the  doctors 
called  it,  in  the  nerve-centres,  he  was  never  thereafter 
fully  himself  again.     He  did  not,  however,  consider  the 
word  "  concussed  "  felicitous.     He  was  pleased  to  learn 
from  Dr.  Roberts  that  it  was  a  good  thing  to  be  fat,  and 
have  a  shield  between  one's  self  and  harm.     He  con- 
sidered this  well  shown  in  Dr.  Hammond's  case,  where 
the  woman  was  saved  by  landing  on  the  voluminous 
natural  cushion  of  her  seating  apparatus.     The  insinua- 
tion which  had  been  made,  that  the  consideration  of  the 
fee  could  swerve  the  testimony  of  the  physician,  he  repu- 
diated, and  said  that  he  stood  up  for  the  honor  of  that 
sacred  calling  which  deals  with  the  mysteries  of  human 
life,  and  which  he  had  always  held  in  reverential  regard. 
From  Dr.  Dana's  paper  he  had  seen  that  he  agreed  with 


Charles  Sumner,  that  what  a  man  most  needed  was  back- 
bone ;  that  wonderful  combination  which  enabled  a  man 
to  stand  erect,  and  firm,  and  unbending,  in  all  emer- 
gencies. 

Dr.  Dana  :  I  only  wish  to  say  with  regard  to  one  or 
two  points  that  Dr.  Johnson  raised,  first,  with  regard  to 
employees  not  suffering  from  this  concussion  of  the  spine ; 
I  think  he  will  find  the  symptoms  of  concussion  of  the 
spine,  as  delineated  by  Dr.  Erichsen,  were  described  by 
Dr.  Abercrombie  twenty-five  years  before  Erichsen 
wrote,  and  his  classification  of  spinal  injuries  would  hold 
good  now. 

He  was  ver}'  glad  that  Dr.  Johnson  brought  out  the  great 
importance  of  the  malingering  element,  because  it  is  an 
important  one.  Every  one  knows  there  is  a  prejudice  in 
juries  against  corporations.  There  are  certain  courts 
where  a  corporation  cannot  get  a  verdict  any  way,  at  least 
so  the  lawyers  say.  Therefore,  I  think  that  in  justice  we 
ought  to  keep  that  fact  of  malingering  before  us  as  being 
a  very  important  one  indeed. 

As  regards  the  trouble  brought  on  in  locomotive  engi- 
neers, he  thought  that  Dr.  Johnson  would  find  that  Dr. 
Rigler,  whom  he  quoted  in  his  work  on  "  Injuries  of  the 
Spinal  Cord,'*  has  devoted  a  good  deal  of  attention  to  this 
disease,  which  he  calls  sideromorphophobia,  or  fear  of 
railways.  He  did  not  think  that  it  was  due  to  continu- 
ous concussion  alone,  because  it  occurred  in  locomotive 
engineers  more  often  than  in  the  other  employees.  It 
seemed  to  the  speaker  that  the  constant  strain  and  anxi- 
ety which  these  engineers  suffered  were  very  important 
elements  in  producing  it. 

In  conclusion,  he  said  that  there  was  a  class  of  cases 
that  had  not  been  much  referred  to  in  the  discussion. 
Nervous  and  hysterical  women,  when  frightened  or  in- 
jured on  a  railroad,  were  very  liable  to  go  to  bed,  and,  un- 
der the  sympathizing  influence  of  friends  and  the  prospect 
of  large  damages,  develop  a  functional  paraplegia  with 
symptoms  of  spinal  irritation.  It  was  often  hard  to  tell 
the  exact  amount  of  real  injury  for  which  the  company 
was  responsible.  As  a  rule  the  companies  were  unjustly 
mulcted,  though  sometimes  the  trouble  became  a  real 
one. 


NORTHWESTERN    MEDICAL  AND   SURGICAL 
SOCIETY. 

Stated  Meetings  November  26,  1884. 

E.  C  Harwood,  M.D.,  President,  in  the  Chair. 

lead-poisoning. 

Dr.  R.  C.  M.  Page  read  a  paper  on  the  above  subject 
(see  p.  62 1 ),  the  discussion  on  which  was  as  follows  : 

Dr.  Flint  :  In  a  meeting  of  this  kind  it  is  more  pleas- 
ant  for  me  to  listen  to  others  than  to  occupy  time  by  my 
own  speaking,  but  I  will  with  pleasure  make  a  few  re- 
marks on  the  paper.  In  the  first  place,  as  to  the  name :  it 
seems  to  me  to  be  a  misnomer  to  call  it  colic  at  all,  as  the 
colon  is  not  specially  involved.  It  has  nothing  to  do  with 
a  spasmodic  affection.  I  consider  that  it  is  a  neuralgic 
affection.  One  curious  fact  in  connection  with  it  is  the 
different  way  in  which  it  manifests  itself  in  different  per- 
sons as  regards  their  susceptibility.  Out  of  any  given 
number  of  persons  who  are  exposed  to  it,  a  certain  num- 
ber only  are  affected  by  it.  I  cannot  explain  this,  and 
do  not  know  that  any  one  has  ever  been  able  to  do  so. 
Another  curious  fact  in  connection  with  it  is  its  limitation 
to  the  extensor  muscles.  I  do  not  know  that  that  has 
ever  been  satisfactorily  explained.  In  many  cases  the 
flexors  remain  unaffected.  I  think  Dr.  Page  will  recol- 
lect a  hospital  case,  many  years  ago,  which  well  illus- 
trated that  fact.  It  was  before  the  elevators  had  been 
introduced,  and  as  it  was  necessary  to  take  the  patients 
firom  the  lower  wards  up  to  the  amphitheatre,  it  was 
sometimes  a  puzzle  as  to  the  manner  in  which  we  could 
do  this.  I  had  a  patient  who  had  the  drop-wrist  to  a  re- 
markable degree,  and  he  had  no  power  over  the  exten- 


638 


THE   MEDICAL  RECORD, 


[December  6,  1884 


sors.  We  wanted  to  take  another  patient  up-stairs,  and 
we  took  this  patient,  who  was  a  very  muscular  man,  and 
raised  his  hands  and  gave  him  a  good  grasp,  which  was 
necessary.  Having  done  this,  he  took  hold  of  the  pa- 
tient and  carried  mm  up  three  or  four  flights  of  stairs 
easily  enough.  That  case  illustrated  to  a  remarkable 
degree,  I  think,  the  fact  that  the  paralysis  was  limited  to 
the  extensors,  and  that  the  flexors  were  exempt.  We 
And  sometimes  the  same  paralytic  effect  on  the  toes,  as 
connected  with  their  extensor  muscles.  I  can  hardly 
agree  with  the  writer  of  this  paper  as  to  the  importance 
of  the  diagnosis  of  the  blue  line.  I  cannot  cite  statistics, 
but  I  am  accustomed  to  find  it  more  often  than  in  the 
data  which  he  has  mentioned.  It  seems  to  me  that  in  a 
large  number  of  cases  we  can  distinguish  the  blue  line 
readily  from  the  discoloration  mentioned,  and  it  is  often 
a  very  useful  point  in  diagnosis.  I  have  been  led  to 
think  that  we  neglect  the  examination  of  the  urine  too 
much.  I  was  led  to  think  so  by  a  case  which  I  saw  sev- 
eral years  ago  with  the  late  Dr.  Stoner  of  this  city.  It  was 
a  case  in  a  child,  seven  years  of  age,  who  had  complete 
paralysis  of  the  flexor  muscles  of  the  forearm.  I  told  Dr. 
Stoner  that  it  was  a  case  of  lead-poisoning.  He  said  : 
"  It  looks  like  it,  it  is  true,  but  it  cannot  be,  for  the  rea- 
son that  it  is  impossible.  This  child  has  not  been  ex- 
posed to  the  causes  which  produce  lead-poisoning.  There 
is  no  possibiUty  of  the  child  having  be6n  exposed  to  lead." 
The  child  at  that  time  did  not  show  the  blue  line.  It 
occurred  to  me  to  have  the  urine  examined.  We  did  so, 
and  sent  a  specimen  of  it  to  Dr.  Doremus,  and  the  ex- 
amination showed  conclusively  the  presence  of  lead.  My 
impression  is  that  it  is  now  a  common  practice  to  examine 
the  urine.  It  is  not  a  difficult  one,  surely.  The  question 
that  arose  after  we  had  found  out  this  much  was.  How  did 
this  lead  get  into  the  child?  After  a  great  deal  of  in- 
quiry the  facts  in  the  case  seemed  to  be  these  :  The  child 
had  been  accustomed  to  play  with  leaden  soldiers,  and 
it  was  recollected  that  he  was  accustomed  to  have  them 
in  his  mouth.  With  respect  to  treatment,  I  am  very 
glad  to  be  able  to  concur  with  the  writer  of  this  paper. 
It  seems  to  be  a  fact  that  the  treatment  formerly  con- 
sisted of  the  stereotyped  drastic  remedies.  The  writers  of 
some  years  ago  followed  a  course  of  treatment  that  con- 
sisted in  the  administration  of  cathartics.  The  French 
writers  on  the  practice  of  medicine  seem  to  observe  that 
method  of  treatment.  I  think  it  is  also  followed  by  the 
English  practitioners  more  than  by  us.  I  cannot  think 
that  it  is  a  rational  method  It  is  injurious  to  a  greater 
or  less  extent.  I  believe  the  plan  that  has  been  indicated 
in  the  paper  is  to  relieve  the  pain  by  opium,  and  pay  no 
attention  to  the  bowels,  except  so  far  as  the  moral  effect 
is  concerned,  or  to  obviate  too  prolonged  a  siege  of  con- 
stipation, and  then  to  eliminate  the  lead  from  the  sys- 
tem by  the  iodide  of  potassium.  I  cannot,  however,  but 
be  somewhat  skeptical  as  to  its  eflficiency.  I  have  given 
it  in  a  great  many  cases  without  any  good  effect  appar- 
ently, and  have  been  ready  to  think  sometimes  that  we 
overestimated  its  value.  In  a  large  number  of  cases 
where  the  iodide  of  potassium  has  not  been  used,  they 
have  ended  about  as  well  as  if  it  had  been  used.  I 
simply  throw  out  that  idea,  however,  and  do  not  give  it 
as  an  opinion. 

Dr.  Little  :  In  what  way  is  the  lead  rendered  vola- 
tile by  turpentine  ?  I  believe  that  Dr.  Page  in  his  paper 
said  that  the  use  of  so  much  turpentine  rendered  the 
paint  volatile,  and  consequently  led  to  its  inhalation  by 
the  painter.  I  did  not  know  that  any  of  the  paint  that 
was  commonly  used  was  volatile  enough  to  be  thrown  oflf 
with  the  turpentine  and  inhaled  by  the  patient.  It  has 
often  occurred  to  me  that  lead-poisoning  is  produced 
by  the  use  of  lead  as  an  astringent.  I  have  never 
yet  seen  a  case,  however,  in  which  lead-poisoning  was 
produced  by  the  use  of  lead  in  this  connection.  Maybe 
its  use,  however,  is  not  continued  long  enough.  I  have 
never  seen  any  bad  efifects  from  the  use  of  the  iodide  of 
potassium. 


Dr.  Blumenthal  :  I  think  Dr.  Page  has  pretty  thor- 
oughly covered  the  whole  field.  The  recognized  treat- 
ment certainly  is  that  which  he  has  just  outlined.  It 
consists,  in  the  first  instance,  in  the  relief  of  pain  by  an 
opiate  treatment  in  conjunction  or  not,  as  the  case  may 
seem  to  demand,  with  croton  oil,  and  after  that  the 
elimination  of  the  lead  from  the  system  by  the  iodide  of  * 
potassium.  If  I  am  not  very  much  mistaken  there  often 
remains  a  good  deal  of  atrophy  after  all  traces  of  lead 
have  been  eliminated  from  the  system.  I  have  often  got 
a  great  deal  of  encouragement  by  the  use  of  nux  vomica 
and  strychnine  while  using  electricity.  The  tonic  treat- 
ment that  has  been  pointed  out  is  certainly  one  in  which 
we  all  agree.  There  is  a  vast  amount  of  difference  in 
the  systems  that  absorb  the  poisons — that  is,  some  will 
absorb  more  poison  than  others  before  they  present  synp. 
toms — and  consequently  there  must  be  a  great  deal  of 
difference  in  the  treatment  that  may  be  necessary  to  pro- 
duce relief.  The  most  probable  reason,  to  my  mind,  why 
the  right  hand  is  affected  oftener  than  the  left  is  that  it  is 
used  more  by  the  workman  than  the  other.  His  right 
hand  is  very  frequently  covered  by  the  paint,  and  cons^ 
quently  there  is  more  opportunity  given  for  the  absorp- 
tion  of  the  lead  than  in  the  case  of  the  left  hand.  Before 
the  patient  feels  the  effect  on  his  system  his  limb  is 
likely  to  be  affected.  Of  course  where  he  is  left-handed 
the  reverse  would  be  the  case.  The  point  which  Dr. 
Flint  raised  is  a  very  important  one,  and  that  is  that  we 
are  too  likely  to  look  after  other  symptoins  and  not  pay 
enough  attention  to  the  urine. 

Dr.  Baruch  :  I  have  used  very  frequently  an  appli- 
cation of  white  paint  to  burns,  just  as  the  painters  do, 
quite  as  thick  as  I  could  use  it — ^just  thick  enough  so 
that  I  could  handle  it  properly.  I  employ  it  in  connection 
with  about  two  per  cent,  of  carbolic  acid.  I  have  used 
this  in  connection  with  dilute  sulphuric  acid  lemonade, 
and  I  would  like  to  have  the  question  settled  here 
whether  there  is  any  necessity  of  giving  a  patient  !his 
sulphuric  acid  lemonade  while  h«  is  being  treated  with 
applications  of  white  paint. 

Dr.  Wood  :  One  idea  has  struck  me  in  Dr.  Baruch's 
address,  and  that  is  whether  we  do  not  run  a  great  risk, 
when  we  use  white  paint  for  several  days  over  a  large 
surface,  of  producing  lead-poisoning ;  and  yet  I  must  say 
that  I  have  never  come  across  such  a  case.  I  have,  how- 
ever, seen  the  symptoms  of  lead-poisoning  from  the  use 
of  lead  internally.  I  once  saw  a  case  that  was  called 
chronic  diarrhoea  in  one  of  our  soldiers  of  the  late  war. 
He  had  been  taking  the  acetate  of  lead,  and  when  he 
came  North  he  continued  it  for  some  time  ;  how  long  I 
am  not  able  to  say.  When  he  returned  he  had  symptoms 
of  lead-poisoning.  I  believe  it  is  generally  conceded 
that  the  drastic  purgative  treatment  of  this  disease  is  not 
cariied  out  to  the  extent  that  is  recommended  in  foreign 
works.  There  is  no  question  but  what  the  soothirg 
opium  treatment  conduces  more  to  the  recovery  and 
convalescence  of  the  patient  than  a  cathartic  treatment 

Dr.  Dessau  :  I  was  quite  surprised  to  hear  the  writer 
of  the  paper  speak  so  disparagingly  of  the  treatment 
which  consisted  of  the  use  of  alum  and  sulphate  of  mag- 
nesia. I  have  used  hypodermic  injections  of  morphine 
to  relieve  pain  also,  but  the  constipation  was  relieved  by 
the  use  of  sulphate  of  magnesia  and  alum,  and  it  was 
used  in  very  large  doses.  I  used  about  a  drachm  of  the 
sulphate  of  magnesia  every  three  hours.  Soon  afterward 
the  bowels  were  relieved.  After  this  the  patient  is  put 
upon  the  iodide  of  potassium  treatment,  but  the  consti- 
pation in  my  case  was  certainly  relieved  by  the  use  of 
alum  and  the  sulphate  of  ma^esia,  because  no  other 
treatment  was  resorted  to.  This  particular  patient  had 
been  constipated  for  a  week. 

Dr.  Fuller  :  I  cannot  say  anything  with  regard  to 
the  treatment  of  the  case,  but  the  other  day  I  had  the 
opportunity  of  observing  the  disease  in  children  of  very 
tender  years.  The  author  of  the  paper  did  not  mention 
particularly  the  occurrence  of  the  aiffection  in  children, 


December  6,  1884.] 


THE  MEDICAL  RECORD 


639 


but  only  spoke  of  adults.  The  cases  I  saw  were  the 
youngest  I  had  ever  taken  notice  of — they  were  only 
three  or  four  years  of  age ;  they  were  undoubted  cases 
of  lead-poisoning.  The  history  of  each  case  could  be 
traced  exactly:  Their  father  was  a  painter,  and  the 
closet  in  his  house  contained  paint;  they  contracted 
the  disease  from  this.  They  had  a  great  many  forms 
of  treatment  applied  to  them  without  any  appreciable 
results.  They  were  afifected  both  in  the  upper  and  lower 
extremities. 

Dr.  Leonard  :  I  saw  an  unusual  case  while  in  the 
Adirondacks,  which  was  diagnosed  as  lead-poisoning. 
After  the  case  had  existed  for  some  months  it  was  cured 
by  the  use  of  the  iodide  of  potassium  treatment.  The 
patient  was  a  hunter  who  had  tried  to  stop  chewing 
tobacco,  and  to  accomplish  this  he  had  put  a  bullet  into 
his  mouth,  and  the  disease  was  attributed  to  this  cause. 

Dr.  Little  :  I  would  like  to  ask  concerning  the  use 
of  sulphuric  acid  as  a  prophylactic.  Dr.  Bsuiich  has 
said  that  it  should  be  used  as  a  lemonade.  I  have  not 
had  any  experience,  but  I  have  noticed  that  it  has  been 
recommended  by  the  authorities. 

Dr.  Flint  :  There  has  been  one  topic  which  has  not 
been  referred  to,  and  that  is  the  relation  of  lead-poison- 
ing to  gout.  It  has  been  asserted  that  gout  has  followed 
where  lead  has  been  introduced  into  the  system.  I  would 
like  to  ask  those  present  if  they  have  ever  known  of  a 
case  where  they  could  attribute  gout  to  lead-poisoning. 

Dr.  Chamberlain  :  Somethmg  has  been  said  about 
hair-washes  as  productive  of  lead-poisoning.  I  recollect 
a  case  twenty-five  years  ago  where  the  disease  was  pro- 
duced by  this  influence.  I  think  it  was  published  in 
Wood's  New  Remedies,  All  of  the  preparations  men- 
tioned contained  lead,  and  evidence  was  brought  forth 
to  show  that  lead-poisoning  was  produced  by  the  use  of 
these  preparations. 

Dr.  Fruitnight  :  It  has  been  emphatically  stated  that 
other  muscles  besides  the  extensors  are  affected.  Last 
summer  a  patient  presented  himself  at  my  office.  He 
worked  in  Western  Pennsylvania.  I  asked  him  to  strip 
himself,  and  on  removing  his  clothing  I  observed  that 
the  muscles  of  the  upper  extremities  were  all  more  or 
less  atrophied.  He  had  to  be  assisted  in  taking  off  his 
clothing.  He  had  worked  a  year  in  the  establishment  in 
which  he  was  at  that  time  employed.  I  endeavored  to 
find  out  every  possible  cause  for  his  condition,  but  was 
forced  to  the  conclusion  that  lead  was  the  cause.  I 
questioned  him  with  regard  to  other  men  working  in  the 
same  establishment,  and  he  told  me  that  a  great  many  of 
them  had  suffered  from  the  drop-wrist.  Another  patient 
was  a  printer  who  had  been  a  very  adept  workman,  but 
It  last  he  became  unable  to  fulfil  his  duties  any  longer  as 
readily  as  he  could  before.  His  muscles  became  weak, 
ind  he  had  pains  and  was  beginning  to  waste  away.  I 
iaw  him  about  two  months  afterward  and  noticed  that 
here  was  no  reaction  to  the  electric  current  either  farad- 
c  or  galvanic.  I  kept  him  under  the  usual  remedies 
or  about  six  months  without  any  effect. 

Dr.  Page,  in  closing,  said :  I  have  very  few  remarks  to 
uake.  In  regard  to  Dr.  Flint's  cases,  where  the  iodide  of 
otassium  failed,  it  is  very  likely  that  the  patients  did  not 
ake  it  regularly  and  continued  to  be  exposed  to  the  in- 
action of  the  poison.  In  that  case  they  were  hardly  fair 
ests.  With  respect  to  the  blue  line,  I  have  nothing 
lore  to  add.  With  regard  to  the  remarks  of  Dr.  Little 
n  the  volatilizing  of  the  paints  by  turpentine,  I  would  say 
lat  I  do  not  know  that  such  is  the  case,  but  believe  it 
)  be  so.  With  regard  to  Dr.  BlumenthaVs  remarks  con- 
eming  nux  vomica,  I  would  say  that  of  course  it  may  be 
[ven.  J  thought  that  I  had  included  it  in  my  remarks 
n  the  general  treatment.  With  regard  to  the  remarks 
f  Drs.  Baruch  and  Wood  about  painting  burns  with 
unt,  I  do  not  think  that  any  burn  will  last  long  enough 
\  cause  the  patient  to  be  poisoned  with  applications  of 
ad,  but  if  it  does,  I  do  not  think  the  sulphuric  acid  will 
revent  it.     I  have  known  painters  to  take  it  regularly 


three  times  a  day  and  yet  be  the  worst  poisoned  men  of 
the  lot.  In  reply  to  Dr.  Dessau^  I  believe  that  the  mor- 
phine cured  the  patient.  My  point  in  regard  to  Epsom 
salts  and  alum  was  that  the  theory  of  sulphuric  acid  acting 
on  the  lead  in  the  system  is  of  no  value.  Concerning 
Dr.  Fuller's  remarks  about  children,  I  must  say  that  I 
never  came  in  contact  with  children  that  had  lead- poison- 
ing, but  that  all  my  cases  were  adults.  Drs.  Chamberlain 
and  Harwood  spoke  of  hair-washes  as  a  cause  of  lead- 
poisoning.  I  would  say  that  they  are  said  to  be  a  frequent 
source  of  lead-poisoning  with  ladies.  There  is  no  way 
to  stop  it  that  I  know  of  except  for  yie  ladies  not  to  use 
them.  You  cannot  make  people  stop  manufacturing 
them.  Consequently  if  ladies  will  use  cosmetic  slops  and 
greases  they  must  expect  to  suffer  the  consequences. 
With  regard  to  what  Dr.  Fruitnight  has  said  about  the 
flexors,  there  is  no  dbubt  in  my  mind  but  what  the  flexors 
become  affected  in  time.  The  reason  I  think  why  it  does 
not  become  more  marked  in  the  flexors  is  because  the 
patient  stops  work  in  time.  He  is  not  exposed  to  the 
poison  any  longer  and  is  undergoing  treatment.  I  know 
of  no  case  of  gout  traceable  to  lead- poisoning. 

Dr.  Wylie  read  a  paper  (see  p.  624)  on  "  Vomiting  in 
Pregnancy,"  the  discussion  on  which  was  as  follows  : 

Dr.  Baruch  had  seen  one  death,  in  consultation, 
resulting  from  vomiting  in  pregnancy.  He  had,  however, 
seen  death  imminent  in  three  different  cases  of  pregnan- 
cy, in  which  he  had  been  forced  to  produce  abortion. 
He  had  noticed  at  that  time,  after  introducing  a  bougie 
into  the  uterus  overnight,  and  allowing  the  remainder  to 
coil  up  in  the  vagina,  that  there  was  no  vomiting.  On  such 
occasions  there  would  be  no  vomiting,  and  labor  would 
not  come  on  for  two  or  three  days.  Two  or  three  hours 
after  the  bougie  was  introduced  the  vomiting  would 
cease.  He  attributed  this  to  the  fact  that  the  connection 
between  the  foetus  and  the  uterus  was  disturbed.  This 
dilatation  of  the  cervix  was  a  dangerous  precedent,  and 
should  be  resorted  to  only  in  desperate  cases.  He  had  used 
it  in  one  case  successfully  !  When  producing  abortion 
he  would  first  dilate  the  cervix  before  going  on.  The 
pathology  was  not  at  all  clear.  He  had  two  cases  of 
sterility.  In  both  he  had  succeeded  in  curing  the  sterility 
by  dilatation.  In  one  of  these  cases  he  had  a  very  bad 
case  of  vomiting,  in  fact  as  bad  as  he  had  ever  seen  not 
to  be  dangerous. 

Dr.  Powell  would  like  to  add  one  case  in  support 
of  Dr.  Wylie's  view.  It  happened  three  of  four  years 
ago.  He  met  Dr.  Wylie  on  the  street,  and  told  him  that 
he  had  been  called  in  to  see  a  woman  suffering  from 
vomiting,  and  gave  the  history  of  this  case.  It  was  the 
fourth  pregnancy,  and  she  had  never  reached  full  term, 
and  premature  labor  had  to  be  brought  on  every  time  to 
save  her  life.  At  Dr  Wylie's  suggestion  the  cervix  was 
dilated  at  once.  Dr.  Powell  went  by  no  especial  rule, 
simply  dilating  it  until  the  woman  said  that  it  pained  her 
a  little.  His  finger  passed  in  for  about  half  an  inch. 
The  result  was  marvellous.  She  went  to  sleep  within 
half  an  hour  afterward,  and  never  had  the  least  trouble 
with  her  stomach.  She  has  been  pregnant  and  delivered 
at  full  term  a  second  time  since. 

Dr.  Fruitnight  said  that  his  brother,  the  late  Dr. 
William  Fruitnight,  had  a  case  in  which  the  obstinate 
vomiting  was  overcome  by  means  of  dilatation  of  the 
cervix. 

Dr.  B.  F.  Dawson  had  no  experience  in  it.  He  had 
not  dilated  a  cervix  in  five  years,  except  for  the  purpose 
of  curetting  the  uterus.  He  would  like  to  ask  Dr.  Wylie 
how  one  dilatation  will  correct  disease  of  the  cervix. 
It  seemed  to  him  a  dangerous  proceeding. 

Dr.  Wylie  did  not  claim  that  it  necessarily  cured  the 
disease,  but  that  it  took  off  the  tension  and  served  to  re- 
lieve any  hardening  that  prevented  the  tissues  from  swell- 
ing. Dilatation  counteracts  the  disease.  He  had  some 
doubts,  the  same  as  Dr.  Dawson,  years  ago,  when  he  first 
tried  dilatation.  These  had  been  dispelled,  however,  and 
six  weeks  ago  he  was  bold  enough  to  dilate  here,  in  his  of- 


640 


THE   MEDICAL   RECORD. 


[December  6,  1884. 


fice,  the  wife  of  one  of  the  ministers  from  Washington,  and 
relieved  her  vomiting  almost  at  once,  which  had  resisted 
much  dosing  by  the  mouth. 

Dr.  Dawson  thought  that  cases  had  been  heard  from 
where  vomiting  occurred  simultaneously  with  pregnancy, 
and  continued  right  along  through  it.  We  all  know  the 
effects  of  warm  water,  glycerine,  and  iodoform,  and  as 
Dr.  Wylie  uses  these  in  making  his  applications,  may  not 
they  be"  the  means  of  giving  relief  ? 

Dr.  Wylie  :  Hardly ;  for  Dr.  Copeman  and  many 
others  cured  by  dilatation,  pure  and  simple.  As  a  rule, 
if  you  examine  woipen  that  are  pregnant  you  will  find 
that  they  have  a  healthy  cervix  when  they  have  no  vom- 
iting, and  when  they  have  vomiting  you  will  find  that 
they  have  a  contracted  or  an  indurated  cervix. 

Dr.  Little  said  that  a  friend  of  his  had  tried  dilatation 
and  found  it  very  good. 

Dr.  Dawson  asked  what  was  the  psychological  effect 
that  was  produced  by  this  act  ? 

Dr.  Wylie  could  not  say. 

Dr.  Copeman  :  In  dilating,  intending  to  induce  abor- 
tion, there  was  an  accidental  delay,  and  he  found  that 
nausea  stopped.  It  happened  in  a  second  case,  and 
then  he  believed  that  dilatation  had  prevented  it.  Quite 
a  number  have  followed  him  since  then,  and  established 
the  fact  that  it  can  be  done  safely  and  satisfactorily. 

Dr.  a.  S.  Hunter  had  no  experience  with  the  dila- 
tation of  the  cervix,  but  he  was  very  glad  of  the  oppor- 
tunity of  listening  to  Dr.  Wylie's  paper,  for  it  encouraged 
him  in  the  use  of  that  means  in  the  event  of  the  failure 
of  medication.  He  had  lost  one  case  in  his  professional 
career  from  severe  vomiting  alone.  The  patient  was 
forty-three  years  of  age,  and  had  vomited  a  great  deal. 
If  labor  had  been  induced  she  would  have  died  without 
any  loss  of  blood.  He  had  been  successful  in  many 
cases  by  the  use  of  oxalate  of  cerium  and  ingurim  ;  five- 
grain  doses  of  each.  It  has  given  prompt  relief.  He 
once  knew  of  a  woman  who  the  morning  after  mar- 
riage was  seized  with  vomiting,  which  continued  for  three 
months.  When  delivery  came  on  it  was  evident  that 
conception  had  occurred  at  that  time.  •  The  patient  that 
he  lost  died  just  before  he  read  the  paper  of  Dr.  Cope- 
man, and  he  was  very  sorry  that  he  had  not  known  of  it 
in  time. 

Dr.  Harrison  agreed  in  most  of  the  conclusions  of 
Dr.  Wylie.  His  only  objection  to  his  etiology  was  that 
it  was  not  quite  comprehensive  enough.  He  had  seen 
one  case  of  obstinate  vomiting.  He  included  every  case 
of  vomiting,  as,  for  example,  any  disease  of  the  kidneys 
or  disease  of  the  stomach,  and  he  came  to  the  conclusion 
that  there  must  be  some  local  cause,  and  in  the  case  he 
had  in  mind  he  thought  he  would  have  to  pioduce  an 
abortion,  as  the  patient  was  so  very  much  exhausted. 
Dr.  Thomas  was  added  to  the  list  of  consulting  ph3'si- 
cians,  and  he  insisted  upon  it,  said  that  it  was  absolutely 
necessary  to  induce  an  abortion,  which  he  did  with  the 
effect  of  curing  the  patient.  In  this  case  the  cause  of 
the  vomiting  was  due  to  peritoneal  irritation  from  pre- 
vious peritonitis.  The  uterus  was  bound  down  by  false 
adhesions,  and  afterward  she  became  pregnant  He 
thought  it  was  the  peritoneal  irritation  produced  by 
the  expanding  uterus  that  caused  the  vomiting.  In 
another  case  of  severe  vomiting  the  patient  had  taken 
some  pills  to  bring  on  an  abortion.  It  produced  gastro- 
intestinal catarrh,  and  subsequently  she  had  an  attack  of 
acute  atrophy  of  the  liver,  which  caused  her  death.  He 
never  saw  a  worse  case  of  vomiting  than  that. 

Dr.  Dawson  asked  how  Dr.  Wylie  would  explain  the 
fact  that  most  women  stop  vomiting  after  a  few  weeks 
without  dilatation. 

Dr.  Wylie  :  After  a  few  weeks  the  cervix  may  soften 
to  such  an  extent  that  the  pathological  condition  which 
may  have  existed  has  been  really  changed  by  the  soften- 
ing process  which  takes  place.  My  experience  has  been 
that  the  dilatation  does  not  necessarily  remove  the  ab- 
normal pathological  conditions  of  the  cervix,  but  relieves 


the  tension  that  seems  to  be  the  cause  of  the  vomiting. 
That  is,  according  to  the  experience  that  I  have  had. 

Dr.  Dessau  had  a  case  once  where  a  woman  called  in 
to  see  him  on  account  of  persistent  vomiting.  She  was 
then  about  in  the  commencement  of  the  ninth  month  of 
pregnancy,  and  she  told  him  that  the  vomiting  had  not 
commenced  until  about  the  month  before.  About  foiu^  or 
five  years  ago  a  case  happened  where  vomiting  terminated 
with  the  birth  of  the  child.  Here  the  vomiting  came  on 
at  the  end  of  pregnancy. 

Dr.  Wylie  said  that  pregnant  women  might  contract 
diseases  that  might  affect  the  cervix,  such  as  venereal 
disease.  He  haS  known  of  one  or  two  cases  where  the 
irritation  of  the  vulva  from  venereal  warts  seemed  to  cause 
the  vomiting. 

Dr.  Jacobus  :  In  a  case  at  his  clinic  one  of  the  patients 
had  lacerated  her  cervix,  which  had  been  treated  by  am^ 
putation  with  galvanic  cautery.  She  did  not  want  to 
become  pregnant,  and  said  that  if  she  did  become  so  she 
would  in  all  probability  miscarry.  Later  she  became 
pregnant,  and  was  quite  put  out  about  it,  and  was  some- 
what disposed  to  blame  the  treatment  for  getting  her  in 
that  condition.  It  amused  her  husband  considerably.  She 
had  practically  no  cervix,  only  an  internal  os.  If  dilatar 
tion  would  be  likely  to  do  harm  I  should  think  it  would 
have  done  so  in  this  instance.  Dr.  Wylie  ought  to  recol- 
lect her,  for  he  sent  her  to  him.  She  did  not  succeed  in 
producing  miscarriage,  and  Dr.  Wylie  dilated  her  os,  and 
the  next  day  she  had  some  symptoms  of  miscarriage. 
After  the  dilatation  she  walked  home  and  took  aloes  pills, 
ajid  had  a  flow.  Then  the  husband  came  around  and 
said  that  the  flowing  had  ceased.  Dr.  J.  sent  back  by 
him  some  morphine  pills.  About  a  month  afterward  she 
came  around  for  some  pills,  and  I  found  that  she  was 
still  pregnant.  She  went  on,  and  in  about  seven  or  eight 
months  had  a  child.  If  dilatation  was  dangerous  and  pro- 
duced miscarriage,  it  should  have  done  so  in  that  case. 
He  thought  that  she  would  have  gone  the  full  time  if  she 
had  had  a  cervix.  She  had  a  flow  of  water  there  for  two 
weeks  on  account  of  a  rupture,  yet  she  was  delivered  of 
a  child  which  lived. 

Dr.  McLaurey  had  seen  some  very  severe  cases,  but 
never  a  fatal  one.  The  most  successfiil  remedy  that  he 
could  use  was  morphine  and  bismuth  and  caffeine.  He 
had  found  that  to  be  a  very  excellent  remedy.  He  had 
never  tried  dilatation.  In  speaking  of  psychological  influ- 
ences he  would  like  to  state  .this.  Occasionally  he  found 
a  lady  complaining  that  as  soon  as  she  becomes  pregnant 
her  husband  becomes  sick.  A  few  weeks  ago  a  lady 
came  to  him  and  said  she  was  pregnant.  I  said  to  her  : 
"  How  do  you  know  you  are  ?  "  She  said,  "  Oh,  as  soon 
as  I  am  pregnant  my  husband  always  becomes  sick. 
This  is  the  third  pregnancy  I  have  had,  and  my  husband 
is  sick  every  day."  He  had  heard  of  this  fact  before, 
but  he  could  not  explain  it,  and  would  like  to  know  if 
there  was  any  one  in  this  room  that  could. 

Dr.  Chamberlain  was  familiar  with  the  paper  of  Dr. 
Copeman,  and  had  employed  his  methods  with  satisfac- 
tion. He  would  remind  the  gentlemen  of  Dr.  Engleman's 
paper  that  was  published.  He  was  inclined  to  regard 
the  interpretation  of  this  nausea  as  a  neurotic  phenome- 
non. The  cervix  is  the  most  important  portion  of  the 
uterus.  Up  to  the  time  of  birth  the  cervix  is  in  volume 
as  great  as  all  the  rest  of  the  uterus,  and  up  to  the  time 
of  puberty  there  is  a  portion  of  the  uterus  that  is  between 
the  reflection  of  the  peritoneum  on  the  bladder  and  on 
the  rectum  and  th6  vault  of  the  vagina ;  a  portion  be- 
tween those  is  of  the  same  volume  as  the  uterus.  The 
lower  portion  of  the  uterus  is  thrown  down,  and  the 
upper  portion  is  thrown  off.  The  cervix  is  the  active 
portion  of  the  uterus.  It  is  through  that  portion  that 
the  nerve  supply  reaches  the  uterus,  and  it  has  been  ob- 
served that  the  neurosies  (?)  of  the  uterus  are  connected 
with  the  cervical  portion.  He  had  dilated  the  uterus 
repeatedly  where  he  had  attempted  to  bring  on  deliveiy 
in  cases  of  convulsions,  and  as  often  as  he  had  done  that 


December  6,  1884.] 


THE  MEDICAL  RECORD. 


641 


thing  he  had  found  that  the  convulsions  had  ceased.  Re- 
peatedlyi  and  he  thought  constantly,  in  every  case  where 
he  had  employed  this  dilatation  of  the  cervix  to  suppress 
vomiting  in  pregnancy,  it  had  been  successful.  He 
recollected  a  case  in  which  a  lady  had  a  small  fibroma 
on  the  posterior  wall  of  the  cervix.  It  acted  like  a  kind 
of  a  ball-valve  over  the  os  internum.  In  that  case  he 
dilated  the  cervix  and  the  vomiting  stopped  and  did  not 
return.  He  was  convinced  from  experience  that  while 
undoubtedly  such  cases  as  Dr.  Harrison  has  cited,  where 
there  is  a  palpable  structural  change,  and  this  may  be- 
come the  cause  of  vomiting,  and  also  in  Dr.  Wy lie's 
cases,  where  he  describes  disease  of  mucous  membrane, 
the  treatment  should  be  that  of  the  mucous  membrane. 
He  was  confident,  nevertheless,  that  the  kind  of  spasm 
which  was  remedied  by  the  process  of  dilatation  was  the 
cause  of  a  great  many  cases  of  severe  vomiting  in  preg- 
nancy. 

Dr.  Wylie  had  nothing  to  say,  but  admitted  the  paper 
was  not  as  broad  as  it  might  be,  as  Dr.  Harrison  said, 
and  it  was  drawn  strongly  in  one  direction  so  as  to  bring 
this  point  out :  that  local  treatment  can  be  given  without 
great  risk,  and  is  in  most  cases  the  best,  and  in  some  the 
only,  means  of  giving  relief. 

The  Society  then  adjourned. 


OUR   LONDON  LETTER. 

(From  our  Special  Correspondent.) 

PULMONARY  SURGERY — ^A  NEW  UNIVERSITY  FOR  LONDON — 
SMALL-POX   AND  CHOLERA — SURGICAL  SCARLET  FEVER. 

Tx>NDON,  November  15,  X884. 

At  the  last  meeting  of  the  Medico-Chirurgical  Society  a 
brief  but  interesting  discussion  took  place  on  pulmonary 
surgery.  Dr.  Cayley  showed  a  specimen  of  cancer  of 
the  oesophagus  associated  with  a  pulmonary  cavity.  The 
cavity  was  tapped  during  life  by  means  of  a  trocar 
and  canula.  It  was  found  at  post-mortem  that  the  pul- 
monary cavity  was  in  communication  with  the  cancerous 
tract  in  the  oesophagus  and  stomach,  and  that  the  fluids 
from  the  diseased  area  passed  into  the  cavity.  The 
case  was  obviously  one  in  which  a  cure  could  not  be  ex- 
pected ;  but  the  operation  afforded  the  patient  great  re- 
lief by  obviating  the  fetid  expectoration  from  which  he 
had  been  suffering.  The  case  also  shows  that  the  lung 
can  be  tapped  without  much  danger.  In  this  case  sev- 
eral punctures  were  made,  without  success,  in  various  di- 
rections before  the  cavity  was  reached,  and  the  patient 
had  not  suffered  therefrom. 

A  proposition  is  on  the  carpet  to  found  a  new  univer- 
sity for  London.  London's  present  university  occupies 
the  anomalous  position  of  being  merely  an  *'  examining 
board,"  though  in  this  respect  it  performs  its  functions 
so  hypercritically  as  to  rather  deserve  the  name  dura — 
than  a/ma — mater.  It  also  stands  in  an  isolated  position 
without  any  very  direct  relation  with  medical  and  other 
colleges,  and  with  practically  no  control  over  the  teach- 
ing its  alumni  receive  before  presenting  themselves  to 
receive  its  official  stamp.  It  is  now  proposed  to  found 
a  new  organization,  with  several  faculties,  with  complete 
university  teaching,  supervised  by  the  university  authori- 
ties, and  to  bring  it  into  close  relation  with  existing 
institutions.  An  attempt  will  be  made  to  merge  the 
present  in  the  new  university.  Active  support  is  al- 
ready promised  from  influential  quarters.  The  Council 
of  Legal  Education  will,  it  is  believed,  support  the 
scheme.  Earnest  support  may  be  expected  from  the 
medical  schools  and  corporations.  The  Normal  School 
of  Science  at  South  Kensington  may  also  not  improba- 
bly throw  in  its  fortunes  with  the  new  scheme. 

There  is  reason  to  fear  an  increase  in  the  small-pox 
epidemic  as  the  winter  comes  on.     The  number  of  cases 


under  treatment  in  the  hospitals,  etc.,  of  the  Metropoli- 
tan Asylums  Board  has  again  increased.  The  number  of 
new  cases  admitted  last  week  was  more  than  double  that 
of  those  admitted  the  previous  week,  viz.,  two  hundred 
and  thirty- three,  as  compared  with  one  hundred  and  one. 

The  outbreak  of  cholera  in  Paris  suggests  the  possi- 
bility of  one  here ;  but  we  can  as  yet  show  a  clean  bill  of 
health. 

At  the  last  meeting  of  the  ivTedical  Society  of  London 
an  interesting  paper  was  read  by  Dr.  De  Haviland  Hall 
on  the  subject  of  "Surgical  Scarlet  Fever,*'  and  was  fol- 
lowed by  a  lively  discussion.  Several  speakers  doubted 
whether  such  cases  were  really  scarlet  fever,  and  it  was 
suggested  that  the  eruption  might  be  really  a  rash  due 
either  to  the  shock  of  the  operation  or  resulting  from  the 
anaesthetic  used.  No  speaker  ventured  to  defend  the 
view  that  the  performance  of  a  surgical  operation  can 
originate  such  a  disease  as  scarlet  fever.  Dr.  Hall 
thought  the  poison  had  been  absorbed  before  the  opera- 
tion, but  that  it  would  not  have  manifested  itself  so  soon 
(in  this  case  on  the  day  following  the  operation)  unless, 
as  Sir  J.  Paget  says,  the  health  had  been  disturbed.  Sir 
J.  Fayrer,  Mr.  R.  W.  Parker,  and  Mr.  Durham  all  re- 
garded the  case  as  one  of  scarlet  fever.  Mr.  Parker 
remarked  that  his  experience  at  a  children's  hospital  had 
taught  him  that  the  occurrence  was  by  no  means  rare  in 
surgical  cases  which  had  recent  wounds,  and  the  scarlet 
fever  might  be  very  severe  and  the  wound  take  on  fresh 
action. 


ON  LARGE  DOSES  OF  THE  POTASSIUM  IO- 
DIDE IN  THE  TREATMENT  OF  THE  LATE 
LESIONS  OF  SYPHILIS. 

To  TUB  Editor  op  Tub  Mbdical  Rbcosd. 

Sir  :  In  The  Record  of  the  2  2d  ult,  p.  584,  Dr.  J.  S. 
Crawcour,  M.R.C.S.  Eng.,  refers  to  an  editorial  on  Dr. 
Seguin's  article  in  the  Archives  of  Medicine^  on  what 
is  claimed  to  be  the  American  mode  of  using  the  iodide 
of  potassium  in  the  late  lesions  of  syphilis.  In  this  ar- 
ticle Dr.  Seguin  is  quoted  as  claiming  that  the  practice 
of  giving  very  large  doses  of  potassium  iodide  in  certain 
cases  has  been  in  vogue  for  over  fifteen  years.  "By 
large  doses  is  meant  such  as  make  up  a  total  of  two  and 
a  half  to  ten  grammes  in  twenty-four  hours."  Dr.  Se- 
guin is  shown  to  have  claimed  that  this  practice  originated 
with  theJate  Dr.  Wm.  H.  Van  Buren,  about  fifteen  years 
since,  and  that  "it  has  received  slight  or  no  adequate 
notice  in  text-books,"  and  that  "it  is  only  in  the  works  of 
Loomis,  Bartholow,  and  of  Van  Buren  and  Keyes,  and 
Bumstead  and  Taylor,  and  of  Buzzard,  abroad,  that  any 
recognition  of  it  is  found." 

Dr.  Crawcour  objects  to  the  claim  made  by  Dr.  Se- 
guin, that  the  administration  of  large  doses  of  potassium 
iodide  in  the  late  lesions  of  syphilis  originated  with  the 
late  Dr.  Van  Buren,  and  thus  was  of  American  origin, 
and  quotes  a  prescription  made  by  himself  in  1859, 
which  calls  for  one  drachm  of  the  potassium  iodide  to  be 
given  four  times  in  the  twenty-four  hours.  He  says  :  "It 
will  thus  be  seen  that  the  method  of  giving  the  iodide  of 
potassium  in  large  doses  is  by  no  means  a  New  York 
method,  but  was  used  in  New  Orleans  twenty-five  years 
ago,  and  as,"  he  says,  "I  had  only  been  in  this  country 
five  years,  it  might  be  more  correctly  termed  an  Eng- 
lish method."  It  appears  to  me  that  Dr.  Crawcour  is  quite 
justified  in  assuming  this  as  far  as  any  statements  made 
by  Dr.  Seguin  are  concerned.  Dr.  Seguin  was  in  error 
not  only  in  attributing  to  Dr.  Van  Buren  the  credit  of 
originating  the  plan  of  treatment  of  late  syphilis  by  the 
iodide  of  potassium  in  large  doses,  but  in  his  statements 
as  to  the  comparative  ignorance  of  the  profession  at  large 
in  regard  to  it,  and  also  that  "  it  is  only  in  the  works  of 
Loomis,  Bartholow,  and  Van  Buren  and  Keyes,  Bumstead 
and  Taylor  in  this  country,  and  of  Buzzard  abroad,  that  any 
recognition  of  it  is  found."  According  to  the  definition 
previously  given  of  large  doses^  anything  above  two  and  a 


642 


THE  MEDICAL   RECORD. 


[December  6»  1884. 


half  graaimes,  1.^.,  about  forty  grains^  may  be  considered 
as  coining  within  the  meaning  of  the  term. 

Ricord,  in  1835,  says  of  the  treatment  of  the  late  lesions 
of  syphilis  by  large  doses  of  the  iodide  of  potassium :  "  Two 
scruples  may  be  given  at  first,  in  three  doses,  in  the  course 
of  a  day ;  fifteen  grains  should  be  added  every  five  days 
until  one  and  a  half  drachm  (about  five  grammes)  are 
taken  a  day,  which  I  have  rarely  gone  beyond."  This 
passage  occurs  in  the  work  of  Hunter  and  Ricord  (on 
Venereal),  of  1835,  and  may  be  found  in  an  American 
edition  of  the  same  edited  by  Dr.  Bumstead,  in  1853,  p. 
470.  Acton,  of  London  (i860),  quotes  the  above  with 
approval.  Lancereaux,  of  Paris  (Sydenham  edition,  p. 
320),  says :  "  The  doses  in  which  iodide  of  potassium  is 
given  vary  from  seven  and  a  half  and  fifteen  grains  to 
forty-five,  sixty,  seventy-five,  and  ninety  grains  in  twenty- 
four  hours.  Some  practitioners  carry  the  dose  to  one 
hundred  and  fifty  ^  one  hundred  and  eighty^  and  two  hun- 
dred and  twenty-five  grains  or  even  more''  Beaumler  on 
syphilis,  in  "Ziemssen's  Cyclopaedia,"  vol.  iii.,  p.  297,  says 
of  the  use  of  iodide  of  potassium  in  the  treatment  of  late 
syphilitic  lesions,  **  even  thirty  or  forty-five  grains  several 
times  a  day  must  be  given  to  attain  a  cure." 

Mr.  Coulson  in  his  treatise  on  "Syphilis"  (London, 
1869,  p.  242),  says  :  **Many  of  the  severer  forms  of  late 
and  visceral  syphilis  will  require  one  drachm,  or  even 
larger  doses,  three  times  daily." 

Hill  and  Cooper  (London,  1881),  in  their  work  on 
'*  Syphilis  and  Local  Contagious  Disorders,"  p.  414,  say,  of 
the  iodide  of  potassium  :  "Forty  to  sixty  grains  three  times 
a  day  will  sometimes  quell  an  obstinate  syphilide  which 
has  resisted  smaller  quantities,  but  larger  doses  than  these 
may  be  required."  I  would  also  refer  to  my  own  book, 
published  in  1883,  P-  i43»  where  the  use  of  iodide  of 
potassium  in  drachm  doses  in  certain  cases,  and  its  con- 
tinuance for  a  long  period,  is  advised  in  the  same  con- 
nection; the  method  of  its  administration  is  distinctly 
indicated.  At  p.  199  et  seq.,  a  case  of^  cerebral  syphi- 
lis is  cited  in  illustration,  where  drachm  doses  of  io- 
dide of  potassium  were  administered  for  several  months 
with  apparent  cure,  and  when  the  withdrawal  of  the 
remedy  under  other  care,  apparently,  resulted  in  the  death 
of  the  patient. 

Inasmuch  as,  besides  this,  I  have  for  the  past  twenty- 
five  years  taught  this  plan  of  treatment  for  the  late  lesions 
of  syphilis  in  my  clinic  at  the  College  of  Physicians  and 
Surgeons,  and  also  for  the  past  ten  years  in  my  wards 
in  Charity  Hospital,  I  would  like  to  be  included  among 
those  who  were  credited  with  having  aided  to  some  ex- 
tent in  spreading  the  knowledge  of  its  great  value  in 
this  country.  I  would  like  also  to  say  that  while  there 
seems  to  me  to  be  some  question  as  to  the  good  taste  in 
claiming  the  plan  of  the  administration  of  large  doses  of 
the  potassium  in  cases  of  the  late  lesions  of  syphilis  as 
an  **  American  plan,"  there  can  be  no  question  that  it 
has  found  its  earliest  and  warmest  advocates  and  teachers 
among  American  physicians. 

Dr.  Seguin  claims  from  personal  inquiry  that  Dr. 
Draper  recognized  its  value  as  early  as  1865 — nineteen 
years  ago.  In  the  same  way,  he  states  that  Dr.  Keyes 
recollects  Dr.  Van  Buren  as  teaching  it  as  far  back  as 
1863 — twenty-one  years  ago. 

Dr.  Taylor  tells  Dr.  Seguin  that  he  has  accepted  it 
ever  since  he  heard  it  taught  by  Dr.  Draper  and  Dr.  Van 
Buren  in  1866.  This  brings  Dr.  Seguin  to  the  con  vie- 
tion  that  the  plan  is  a  purely  American  one,  and  was  in- 
stituted by  Dr.  Van  Buren.     Dr.  Seguin  is  in  error. 

Dr.  William  Kelly  was  Physician-in-Chief  in  Charity 
Hospital,  Blackwell's  Island,  N.  Y.,  from  1848  to  1853. 
He  was  a  man  of  marked  ability  and  thoroughly  inter- 
ested in  all  advances  in  medical  science ;  and  was  an 
especial  admirer  of  M.  Ricord,  and  in  harmony  with  his 
views  on  the  treatment  of  syphilis. 

In  185 1  and  1852  I  was  an  interne  in  that  hospital, 
together  with  Professor  Loomis  (who  is  cited  as  approv- 
ing the  potass,  iodide  plan),  also  Dr.  William  Chamber- 


lain, now  one  of  the  Visiting  Physicians  to  Charity  Hos- 
pital, Dr.  J.  W.  Barstow,  of  Sanford  HaU,  Flushing,  amd 
others.  The  plan  of  treating  the  late  lesions  of  syphilis 
with  large  doses  of  potassium  was  then  in  vogue  in  Char- 
ity Hospital,  thus  thirty-three  years  ago.  Dr.  Kelly,  then 
Physician-in-Chief  to  Charity  Hospital,  was  also  a  lect- 
urer on  Venereal  Diseases  at  the  College  of  Physidans 
and  Surgeons,  New  York,  at  that  early  period,  and 
taught  the  foregoing  plan  in  the  college  and  in  the  wards 
of  Charity  Hospital 

After  Dr.  Kelly's  death  his  private  case-books  came  as 
a  valued  legacy  to  me.  Among  the  cases  in  book  E., 
1852,  on  page  6,  I  find  the  following :  "  Ulcers,  syph. 

phagedenic,  by  large  doses  of  iod.  pot    Mary  N was 

.admitted  to  hospital  February  14,  185 1 ;  had  secondaiy 
eruption  and  enlarged  glands  and  falling  of  hair  in  184^ 
.     .     .     At  time  of  admission  body  was  covered  with 
ulcers,  some  rupetic  and  some  ecthymatous.    .    •    .  Was 
put  on  generous  diet,  morphine,  and  iodide  of  potassimn. 
This  latter  was  carried  up  to  two  drachms  per  diem.  Un- 
der  this  patient  got  apparently  well,  and  was  discharged 
September  i,  185 1.      Was  readmitted  to  hospital  one 
month  after  with  ulcers  on  ankles.     Periostitis  of  tibia 
occurred ;  surface  over  it  ulcerated  ;  treated  with  poultices 
and  iodid.  potass.     Local  applications— creasote   ung., 
tabaci,  nit.  arg.,  etc. — failed  to  relieve  pain.     Iodide  of 
arsenic    was    tried    until   its    inefficiency  was    proved 
Mercury  in  small  doses.     Patient  all  the  time  on  ale  and 
good  diet. 

"April  26,  1851. — Determined  to  try  iod.  pot  in  large 
doses.  The  ordinary  doses  up  to  3j-3ij.  had  failed. 
The  dose  was  then  gradually  increased,  so  that  she  took 
5  ss.  of  the  salt  each  day.  She  began  at  once  to  im- 
prove. Pain  ceased  in  two  days,  and  healthy  action  of 
ulcers  set  in.  She  sat  up  for  half  a  day  on  May  5th  for 
the  first  time  in  four  months.  Now — May  nth — can  sit 
sit  up  all  day.  Has  taken  six  ounces  of  the  iod.  pot  to 
this  date," 

There  are  in  the  same  book  several  other  cases  reported 
in  full,  which  are  in  complete  accord  with  the  one  quoted 
above,  showing  that  this  was  the  accepted  practice  in 
Charity  Hospital  at  that  time.  I  would  then  claim  for 
Dr.  Kelly  the  priority  in  systematically  and  successfully 
treating  the  late  lesions  of  syphilis  by  means  of  large 
doses  of  the  iodide  of  potassium  and  of  teaching  this 
method  in  public 

There  seems  to  me  an  important  difference  of  opinion 
between  the  editor  of  The  Record  and  Dr.  Seguin, 
whose  paper  on  the  **  Dosage  of  Potassium  Iodide  "  was 
the  original  subject  of  comment,  in  regard  to  the  best 
mode  of  administering  the  drug.  Dr.  Seguin  states  that 
a  singular  unanimity  prevails  among  autliorities  in  advising 
that  the  iodide  of  potassium  should  be  taken  after  meals 
— he  states  that  no  good  physiological  reason  can  be 
^iven  for  this  rule,  and  he  says,  ''  I  strongly  suspect  that 
It  is  nothing  more  than  the  blind  following  after  example." 
He  therefore  advises  that  it  be  always  given  upon  an 
empty  stomach.  The  editor  of  The  Record  disagrees 
with  him,  and  advises  pursuance  of  the  rule  advised  by 
authorities.  The  reason  why  the  drug  is  usually  given 
after  meals  is,  I  think,  because  it  is  less  likely  to  produce 
irritation  of  the  mucous  membrane  of  the  stomach.'  It 
occasionally  happens  that,  even  when  every  possible  care 
is  taken,  such  disturbance  of  the  stomach  results  that  the 
use  of  the  drug  has  to  be  discontinued.  The  life  of  a 
patient  may  depend  upon  his  ability  to  bear  a  certain 
amount  of  the  iodide.     A  very  moderate  experience  with 

'  I  have  at  present  under  my  care  a  worthy  and  very  intelUgeat  member  ofovr 
profession  suflfering  with  ^ve  ulcerations  on  the  throat  from  late  syjrfiOn.  Tbe 
original  trouble  was  acquired  in  attending  a  syphilitic  woman  durini(  oonfinemcm 
The  ulceration  continued  to  prosress  until  dracnm  doses  of  the  iodide  of  pocaissiaB 
were  taken  every  six  hourn.  This  amount  C  3  j.)  was  administered  after  tmemh 
in  an  ounce  of  water,  and  followed  quickly  by  a  tumbler  of  milk.  On  beinc  ques- 
tioned yesterday  as  to  the  effect  of  these  Urge  doses  on  his  digestive  appaxacat. 
he  said,  "  My  appetite  and  digestion  are  excellenL  My  stomach  bears  oie  iodide 
much  better  when  taken  after  food.  I  do  not  feel  the  effisct  of  sixty  grains  nz  a 
dose  as  much  as  I  formerly  did  Ji/tten  grains,  well  diluted,  but  on  an  cmpcr 
stomach.  The  only  time  I  feel  any  tendency  to  nausea  is  just  after  die  dose  1 
take  at  one  o'clock  a.m.,  when  I  follow  it  with  a  tumbler  of  nulk,  but  on  aa  odter 
wise  empty  stomach." 


V 


December  6,  1884.] 


THE  MEDICAL   RECORD. 


643 


the  use  of  the  iodide  of  potassium  in  large  doses  will  be 
sufficient  to  prove  the  increased  tolerance  to  the  drug 
when  administered  largely  diluted  with  some  bland  fljuid 
as  milk,  or  some  mucilaginous  decoction ;  especially 
when  administered  after  a  meal.  Beginning  with  eight  or 
ten  grains,  the  gradual  increase,  say  by  a  grain  or  two  (or 
even  three  in  an  emergency)  at  each  dose,  and  taken 
with,  or  immediately  followed  by  a  tumbler  of  milk  or 
gruel,  preferably  after  a  meal,  has  proved  in  my  experi- 
ence the  most  free  from  danger  of  irritating  the  stom- 
ach. I  have  recently  had  a  case  under  my  care  where 
3  xij.  were  thus  administered  in  twenty-four  hours,  for 
three  months,  without  disturbance  of  the  stomach,  and 
with  the  effect  of  relieving  almost  completely  a  serious 
paralysis  of  the  bladder  and  rectum,  following  constitu- 
tional  or  active  syphilis.  This  is  the  largest  amount  I 
have  ever  administered  in  a  case  during  the  same  time 
The  assertion  made  by  Dr.  Seguin,  that  **  iodism  is  in 
nowise  dangerous^  and  is  only  an  inconvenience  and  a 
drawback  to  treatment,*'  is  scarcely  justifiable  when  a 
moderate  amount  of  iodide  of  potassium  will  sometimes 
cause  such  irritation  and  swelling  of  the  mucous  membrane 
of  the  fauces  and  air-passages  as  to  place  a  patient's  life 
in  peril.  Such  a  case  is  quoted  in  Hill  and  Cooper,  page 
425,  when  tracheotomy  was  required  to  save  life.  I  have 
myself  seen  the  same  accident,  threatening  death  from 
oedema  of  the  glottis,  when  only  twenty  grains  of  potass., 
thrice  daily,  were  being  administered. 

F.  N.  Otis,  M.D. 

108  Wbst  Thirty-fourth  Strbst,  New  York,  November  23,  18&4. 


MR. 


LAWSON  TAIT  AND  LISTERISM  IN 
OVARIOTOMY. 

To  THB  Editor  op  The  Medical  Record. 


Sir  :  I  have  just  seen  in  the  columns  of  your  valuable 
paper  a  paragraph  headed  **  Another  War  over  Listerism 
and  Ovariotomy,*'  in  which  you  extract  from  Mr.  Thorn- 
ton's letter  in  the  American  Journal  of  Obstetrics  certain 
figures  which  Mr.  Thornton  supplies  on  behalf  of  Dr. 
Bantock  and  myself.  I  can  safely  leave  Dr.  Bantock  to 
deal  with  his  part  of  the  question.  Concerning  my  part 
I  can  only  say  that  I  am  not  responsible  in  any  way  for 
any  figures  which  Mr.  Thornton  may  credit  me  with.  So 
far  as  I  can  make  out,  Mr.  Thornton's  present  figures  are 
those  which  he  manufactured  for  me  on  a  previous  occa- 
sion, and  which  require  to  be  corrected  as  follows  : 


Cases.  Deaths. 
Clamp  (non-Listerian) ...     36  9 

Clamp  (Listerian) 26  7 

Ligature  (non-Listerian)..  209  6 

Ligature  (Listerian) 30  2 


301 


24 


Mort.  per  cent. 
25.0 
27.0 

3.0 
6.6 

8.0 


From  this  statement  it  will  be  seen  by  any  one  who  can 
reason  on  the  subject  at  all  that  so  far  as  my  practice  is 
concerned  Listerism  has  no  effect  one  way  or  the  other, 
and  that  the  heavy  mortality  in  the  early  part  of  my 
practice  was  due  mainly  to  the  clamp,  assisted  of  course 
by  the  factor  of  want  of  experience,  which  always  tells. 
Mr.  Thornton  lumps  my  non-antiseptic  cases  together, 
and  ignores  the  fact  that  they  contain  this  heavy  clamp 
mortality.  This  he  does,  of  course,  because  the  question 
between  us  is  as  to  whether  it  is  the  clamp  or  not  which 
has  been  the  root  of  all  our  evil.  The  suppression  of  the 
further  dissection  of  my  statistics  which  I  gave  is  not 
honesty  particularly  after  the  discussions  which  have 
already  taken  place  on  this  subject  The  concluding 
sentence  of  your  paragraph  says  that  ''  it  is  known  that 
Mr.  Tait,  when  still  a  rising  variotomist,  was  hardly 
treated  with  fairness  by  the  London  gentlemen  whom  he 
now  in  his  triumph  too  rancorously  assails."  I  am  soiTy 
that  I   am  too  rancorous  on  the  subject,  -and  for  the 


future  1  shall  endeavor  to  modify  my  expressions  within 
limits  which  I  trust  may  seem  to  you  to  exclude  rancor ; 
but  if  you  knew  in  what  manner  I  have  been  assailed, 
what  vile  charges  have  been  made  against  me  behind  my 
back  by  Mr.  Thornton  and  others,  which  they  never  dare 
even  to  hint  at  in  public,  you  would,  I  think,  agree  with 
me  that  no  kind  of  language  could  be  too  rancorous  in 
dealing  with  such  men. 

Your  obedient  servant, 

Lawson  Tait. 

P.  S. — I  am  just  closing  my  first  thousand  cases  of 
abdominal  section,  and  as  soon  as  I  can  I  shall  send 
you  a  summary  of  conclusions,  and  after  that  I  shall 
trouble  myself  not  a  brass  farthing  about  Listerism  or  its 
advocates.  L.  T. 

Birmingham,  Enc.  November  14,  1884. 


TRACHEOTOMY  IN  CROUP. 

To  THE  Editor  of  The  Msdical  RscoRn. 

Sir:  In  The  Record  of  November  15th  there  ap- 
peared an  interesting  and  forcible  article  by  Dr.  Simon 
Baruch,  advocating  an  early  operation  in  membranous 
croup,  and  giving  as  a  basis  for  his  argument  the  clinical 
histories  of  three  cases.  I  cannot  but  dissent  from  the 
conclusions  of  the  author,  because  I  believe  that,  if  tra- 
cheotomy were  ginerally  performed  early  in  croup,  many 
children  would  be  unnecessarily  subjected  to  it,  and 
cures  which  would  have  been  either  spontaneous  or  the 
result  of  medical  treatment  attributed  to  it.  To  do  the 
operation  early  one  must  often  do  it  almost  at  the  onset 
of  the  symptoms,  for  frequently  only  a  few  hours  find  the 
patient  in  great  danger  from  asphyxia ;  while  often  the 
symptoms  which  have  seemed  so  threatening  as  to  war- 
rant an  operation  may  yield  and  the  patient  recover. 

From  choice  or  necessity,  most  operators  do  tracheot- 
omy in  cases  of  imminent  danger,  and  are  actuated,  I 
think,  more  by  the  desire  to  relieve  the  patient,  if  only 
temporarily,  from  the  fearful  suffering  which  even  they 
cannot  witness  with  equanimity,  rather  than  inspired  by 
any  great  hope  of  saving  life.  I  do  not  think  that  clini- 
cal experience  bears  out  the  belief  that  a  late  operation 
prejudices  its  success,  for  the  patients  seldom,  if  ever,  die 
of  exhaustion.  The  almost  invariable  history  of  those 
who  die  is  that  they  succumb  to  an  extension  of  the  dis 
ease  below  the  tube,  or  to  the  general  efifects  of  the  dis- 
ease, or  worst  of  all,  to  the  accidental  stopping  of  the 
tube. 

I  believe,  therefore,  that  while  he  who  operates  as  a 
last  resort  occasionally  saves  a  life,  the  early  operator 
does  the  operation,  in  some  cases  at  least,  which  would 
have  recovered  without  it.  I  am  greatly  strengthened  in 
this  opinion  by  having  observed  several  cases  of  mem- 
branous croup  recover  without  tracheotomy,  whose  con- 
dition seemed  most  desperate.  One  expelled  the  mem- 
brane in  a  large  cast,  while  in  a  hot  bath  into  which  it 
had  been  placed  while  almost  completely  asphyxiated, 
and  two  recovered  under  a  plan  of  treatment  which  1 
will  now  describe,  while  giving  the  clinical  history  of  the 
most  recent  case.  I  will  premise  by  saying  that  the  other 
case  alluded  to  only  differed  from  the  one  detailed  in  that 
the  patient  was  a  year  older.  Both  were  in  a  condition 
which  would  have  justified  an  operation,  and  in  both 
cases  I  am  sure  their  cure,  had  it  been  done,  would  have 
been  attributed  to  it.     I  was  called  to  see  the  patient,  a 

little  girl,  W ,  two  years  of  age,  on  the  evening  of 

November  15  th,  and  found  that  she  had  been  ill  all  the 
week,  and  croupy  for  two  or  three  days.  The  parents 
had  not  considered  her  condition  dangerous,  however, 
until  a  few  hours  before  I  saw  her,  nor  had  any  treatment 
been  used.  I  found  her  breathing  with  the  greatest  dif- 
ficulty, 50  to  60  a  minute  ;  the  pulse,  140 ;  and  epister- 
nal  and  abdominal  retraction  well  marked.  Inspection 
showed  diphtheritic  patches  upon  the  tonsils,  and  every- 
thing indicated  a  speedy  asphyxia  unless  relief  could  be 


644 


THE  MEDICAL  RECORD. 


[December  6, 1884, 


obtained.  I  was  deterred  from  advising  an  immediate 
operation  by  the  fact  that  at  two  years  the  prospect  of 
success  is  not  flattering,  and  by  a  lingering  hope  inspired 
by  the  previous  case,  that  the  relief  might  perhaps  be  ob- 
tained by  other  means.  I  must  confess,  too,  that,  having 
done  tracheotomy  for  croup  seven  tjmes,  with  only  one 
successful  result,  I  am  not  as  enthusiastic  in  its  advocacy 
as  I  would  be  had  I  saved  one  in  three. 

To  return  to  the  case  in  hand  : 

I  ordered  equal  parts  of  powdered  alum  and  sulphur 
to  be  blown  into  ^e  throat  at  the  moment  of  deep  in- 
spiration (from  an  insect  powder  blower)  as  often  as 
asphyxia  threatened. 

This  was  done,  and  the  child  struggled  through  the 
next  thirty-six  hours,  expelling  shreds  of  membrane  after 
the  insufflations  at  frequent  intervals,  until  at  length,  on 
the  fourth  day,  the  respiration,  though  somewhat  difficult, 
was  much  deeper  and  freer,  and  all  membrane  had  van- 
ished from  the  throat  in  view.  The  child  has  now  been 
quite  well  for  several  days.  I  am  not  an  enthusiastic 
therapeutist,  and  hardly  thought  of  this  as  an  efficient 
treatment  for  true  croup,  until  this  last  and  desperate  case 
yielded  to  it. 

What  convinces  me,  or  at  least  leads  me  to  hope,  that 
it  may  really  be  a  means  of  combating  the  disease,  is 
the  fact  that  its  use  leads  palpably  and  obviously  to  the 
expulsion  of  the  membrane,  and  this  makes  the  cure 
seem  a  logical  sequence,  rather  than  a  |ucky  chance. 

I  desire  expressly  to  disclaim  any  idea  of  originality  in 
calling  attention  to  this  mode  of  treatment  for  croup,  my 
only  desire  being  to  secure  for  it  a  fair  trial.  Let  it  be 
used,  when  used  at  all,  freely  and  energetically. 

S.  S.  Jones,  M.D. 

809  Lexington  Avenue,  November  35th. 

Official  List  of  Changes  in  the  Stations  and  Duties  of  Officers 

serving  in  the  Medical  Department^  United  States  Army^ 

from  November  23  to  November  29,  1884. 

LoRiNG,  L.  Y.,  Captain  and  Assistant  Surgeon.  As- 
signed to  duty  as  Post  Surgeon,  San  Diego  Barracks, 
San  Diego,  Cal.  S.  O.  135,  Depai»'nent  of  California, 
November  19,  1884. 

Wilson,  George  F.,  First  Lieutenant  and  Assistant 
Surgeon.  Granted  one  month's  leave  of  absence,  from 
November  20th.  (Vancouver  Barracks,  Washington 
Territory.)  S.  O.  180,  Department  of  California,  No- 
vember 18,  1884. 

Wales,  Philip  G.,  First  Lieutenant  and  Assistant 
Surgeon,  now  at  Fort  Coeur  d*Alene,  Idaho  Territory. 
Ordered  for  temporary  duty  at  Vancouver  Barracks, 
Washington  Territory.  S.  O.  179,  Department  of  Cal- 
ifornia, November  17,  1884. 


plcdicaX  Itjems. 


Contagious  Diseases — ^Weekly  Statement. — Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  November  29,  1884 : 


Week  Ending 

9 

% 

1 

£ 

1 

1 

s 

1 

1 

November  22,  1884 

November  29,  1884I 

0 

0 

29 
42 

54 
52 

6 
2 

115 
90 

55 
55 

0 
0 

1 
0 

Deaths, 

November  22,  1884 

November  29,  1884 . 

0 
0 

9 
15 

15 
H 

6 

2 

14 
23 

28 
26 

0 
0 

I 
0 

The  Value  of  Human  Life. — At  the  International 
Congress  of  Hygiene,  at  the  Hague,  Dr.  Jules  Rochard 
of  Paris,  gave  an  address  on  this  subject     He  called  at- 
tention to  the  commercial  value  of  human  life  and  to  the 
loss  occasioned  by  sickness  and  death ;  and  then  pro- 
ceeded to  consider  the  question,  whether  hygiene  was 
capable  of  producing  improvement.     In  doing  so,  he  re- 
ferred to  the  disappearance  of  diseases  which  once  devas- 
tated countries.     The  black  death,   which  destroyed  a 
.fourth  part  of  the  inhabitants  of  the  world,  forty  millions  in 
Europe  alone,  had  become  almost  unknown ;  and  many 
other  diseases,  to  which  our  forefathers  gave  most  for- 
midable  names,  only  remained  in  memory.     In  the  same 
way,  diseases  of  modern  days  ought  to  disappear.    A^. 
ready  the  occurrence  of  the  plague  was  only  sporadic  • 
ague  had  still  a  few  victims  ;  but  cholera  still  threatened 
Small-pox,   measles,  and  scarlet  fever  were  all  diseases 
against  which  protection  could  be  afforded.     This  vas 
best  known  in  the  case  of  small-pox ;  and  he  was  con 
vinced  that  the  time  would  come  when  a  father  would  be 
punished  for  having  unvaccinated  children  in  his  house  as 
much  as  for  having  dynamite  or  gunpowder  in  his  cellar. 
The  value  of  vaccination  was  beyond  all  doubt ;  and  in 
Amenca  and  England  precautions  had  long  been  taken 
against  measles  and  scarlet  fever.     By  adopting  proper 
methods,  disease   would  be  made  to   disappear.    The 
speaker  referred  also  to  the  researches  of  Villemin  and 
Koch,  in  their  bearing  on  the  reduction  of  the  mortality 
from   pulmonary  consumption.      Severe  legislation  was 
not  admissible  ;  but  care  should  be  taken  to  prevent  the 
marriage  of  phthisical  subjects  ;  to  separate  the  phthisical 
from  other  persons  in  hospitals,  dormitories,  etc. ;  and  to 
prevent  the  use  of  tuberculous  meat.     Endeavors  should 
also  be  made  to  cause  the  disappearance  of  malaria  by 
the  drainage  of  marshes.     In  Holland,  however,  it  was 
scarcely  necessary  to  say  this,  for  the  whole  country  was 
a  marsh,  which  through  the  courage  and  energy  of  the 
people  had  been  dried  and  converted  into  beautiful  val- 
leys.    He  would  not  absolutely  assert  that  all  the  germs 
of  death  and  disease  could  be  removed  by  sanitary  meas- 
ures.    Hygiene   could   not   entirely  displace  medicine. 
For,  even   when   hereditary   diseases   disappeared,  new 
diseases  took  their  place ;  anaemia,  diseases  of  the  ner- 
vous system,  alcoholism,  morphinism,  and  many  othen 
which  were  the  results  of  the  vices  of  mankind. 

Iodide  op  Silver. — Dr.  Sedan  advocates  the  use  of 
iodide  of  silver,  especially  in  purulent  affections  of  the 
eye.  The  salt  is  said  to  exceed  in  antiseptic  power  even 
the  bichloride  of  mercury.  The  dosage  is  not  given. 
— Recueil  ct  Ophthalmologies  November  8,  1884, 

Inhalation  ofthe  Vapor  of  Glycerine. — Dr.  Castle, 
of  this  city,  writes  concerning  the  abstract  of  an  article  in 
the  Revue Medicale  (Medical  Record,  October  1 1, 1884), 
which  refers  to  the  benefit  to  be  derived  from  the  inhala- 
tion of  vapor  of  glycerine  by  patients  suffering  from  a 
fatiguing  or  painful  cough.  He  thinks  there  must  be 
some  mistake  about  this,  for  glycerine  is  not  volatile  at 
ordinary  temperatures,  and  when  vaporized  in  the  manner 
described,  without  the  presence  of  vapor  of  water,  it  is 
very  apt  to  be  decomposed  and  give  off  acreolin,  which 
would  prove  anything  but  comforting  to  the  respiratory 
organs  of  the  person  subjected  to  the  experiment. 

Jews  as  Physicians..— Dr.  C.  H.  Von  Klein  says  in 
the  Journal  of  the  American  Medical  AssocicUion^  that 
sixty-seven  per  cent,  of  Jewish  physicians  maintain  pro- 
fessorships in  medical  colleges ;  thirty-six  per  cent  arc 
medical  authors.  Medicine  appears  to  be  the  favorite 
study,  and,  as  a  rule,  they  always  maintain  a  high  stand- 
ing. There  have  been  many  Jewish  physicians  in  a 
professional  capacity  at  the  courts  of  famous  kings.  The 
celebrated  Maimonides  was  physician  to  King  Salahed- 
din,  of  Egypt;  Rabbi  Meir  to  the  King  of  Castile; 
Zedekiad,  physician  to  Louis  the  Pious  of  France,  and 
Montalto  to  Queen  Marie  of  Medicis. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  24 


New  York,  December  13,  1884 


Whole  No.  736 


<3^0itmX  ^xXitltB. 


IS  THE   OPERATION  OF  TRACHEOTOMY  IN 
DIPHTHERITIC  CROUP  DANGEROUS?' 

When  Should  the  Operation  be  Performed? 

By  JOSEPH   E.  WINTERS.  M.D., 

CUNICAL  PROPKSSOK    OP     DISBASSS    OP    CHILDREK,  MBmCAL    DEPAXTMENT    UNI- 
VERSITY OF  CITY  OP  NEW  YORK. 

At  the  March  meeting  of  the  Obstetrical  Section  of  this 
Academy  it  was  stated ^  that  "tracheotomy  is  an  opera- 
tion attended  with  great  immediate  danger  to  the  life  of 
the  patient/' '  This  statement  was  so  startling  to  me  and 
so  at  variance  with  my  impressions  from  reading,  and  from 
Boy  own  personal  experience,  that  I  believed  it  to  be  er- 
roneous. The  opinion  that  tracheotomy  is  a  dangerous 
surgical  operation  I  believe  has  no  valid  foundation,  nor 
will  it  bear  the  test  of  a  close  examination,  and  should 
not  be  accepted  with  the  confidence  with  which  it  seemed 
to  be  received  in  this  hall  last  March. 

The  speaker,  in  the  closing  discussion,  in  corrobora- 
tion of  his  opinion,  quoted    Mr.  Timothy   Holmes,  of 
London,  as  saying  that  the  operation  is  the  most  danger- 
ous of   any  in   surgery.     On  page  303  of  Mr.  Holmes' 
work  on  the  "Surgical  Treatment  on  Diseases  of  Chil- 
dren "  will  be  found  the  following :  "  I  think  that,  of  all 
the   operations  which  we  are  commonly  called  upon  to 
perform  on  children,  tracheotomy  is  the  most  dangerous, 
both  in  its  immediate  performance  and  in  its  secondary 
complications."     And  further,  "  I  would  not  recommend 
tracheotomy  while  any  prospect  of  recovery  existed  other- 
wise."    If  this  suggestion  of  Mr.  Holmes  is  followed,  de- 
lay \n    the    performance  of  the   operation   should    be 
ascribed  as  the  cause  of  both  the  secondary  complica- 
tions, and  of  death,  rather  than  the  operation  itself.     On 
page    302    he  says :  "In  thirty-one  cases  the  causes  of 
death  have  been  noted  ;  and  in  very  few  of  these  cases 
was  the  cause  of  death  connected  in  any  way  with  the 
operation."    ,    .    .   The  original  disease  caused  death  in 
fourteen  cases,  "  pneumonia  and  catarrh  in  twelve,  scar- 
let fever  in  three,  collapse  of  the  lung  in  one,  secondary 
hemorrhage  (fifth  day)  in  one,"  making  the  total  number 
thirty-one,  in  none  of  which  was  the  cause  of  death  in 
any  way  connected  with  the  performance  of  the  operation, 
^OT  Mr.  Holmes  states  on  page  326  that  the  ulceration 
which  caused  the  secondary  hemorrhage  was  produced 
by  the  tube.     On  page  316  he  says  :  "Considering  the 
risk  of  operating  below   the   thyroid  isthmus,  and  the 
largQ  size  and  vascularity  of  that  body  at  an  early  age,  I 
would  urge  the  propriety  of  making  the  opening  above 
the    isthmus.     .     .     .     After  the  age  of  five,  or  there- 
abouts, the  surgeon  can.  if  he  prefer  it,  open  the  trachea 
below  the  thyroid  isthmus.     But  I  do  not  myself  recom- 
mend   this   operation,  at  any  rate  before  puberty.'*     On 
page  318  it  is  stated  :  "To  cut  through  the  isthmus  of  the 
thyroid  is,  in  early  life  at  least,  a  dangerous  proceeding." 
Speaking  of  hemorrhage,  Mr.  Holmes,  on  page  317, 
says  :  '*  I  have  three  times  seen  death  on  the  table  during 
tracheotomy  ;  and  twice  from  this  cause.     In  one  case, 
in  which  I  w^as  myself  the  operator,  the  child  was  very 

'  Read  before  the  Section  of  Obstetrics  and  Diseases  oi  Women  and  Chil- 
dren, October  33d>  and  by  invitation  was  reread  before  the  Academy  at  large, 
necember  4tb. 

*  jyr,  Ripley,  Mbdical  Rrcord,  April  5,  1884,  ^age  360. 

'  ''The  operratlon  of  tracheotomy  in  young  children  ror  croup,  in  its  imminent 
peril  to  life^  is  one  of  the  most  dangerous  operations  in  surgery."  (Dr.  Ripley, 
Mkoicai,  Record,  July,  31,  1880,  page  zi8.) 


youn^  (age  not  given).  On  exposing  the  parts,  I  dared 
not  divide  the  centre  of  the  thyroid  body,  on  account  of 
its  thickness,  and  the  large  size  of  the  vessels  visible  in 
it.  On  the  other  hand,  to  open  the  trachea  below  I  had 
Xo  plunge  my  knife  almost  beneath  the  sternum.  .  .  . 
In  the  incision  a  vein  was  cut  very  near  to  its  opening  into 
the  left  innominate,  and  the  bleeding  proved  fatal  before 
I  could  get  the  tube  in." 

In  the  first  volume  of  Trousseau,  page  423,  he  says :  "  I 
have  often  witnessed  the  difficulties  and  dangers  of  a  too 
nimble  tracheotomy,  even  when  performed  by  an  able 
operator.*' 

Marsh  *  says :  "  It  would  be  nearly  as  reasonable  to 
cut  straight  down  upon  the  subclavian  artery  as  to  at- 
tempt tracheotomy  as  it  is  very  often  performed,  and  it 
would  be  scarcely  more  dangerous.  The  amount  of  hemor- 
rhage during  tracheotomy  will  depend  almost  entirely  on 
the  method  of  operating." 

Mr.  Durham "  says  that  of  one  hundred  and  eight  cases 
of  tracheotomy  at  Guy's  Hospital,  performed  during  a 
period  of  twelve  years,  there  was  not  a  single  case  of 
serious  hemorrhage,  and  the  operations  were  performed 
by  the  house  surgeons  in  a  very  large  proportion  of  the 
cases,  and  that,  too,  very  often  under  circumstances  of 
peculiar  emergency  and  difficulty. 

Of  eighty-seven  cases  reported  in  vol.  ix.  of  The  Medical 
Times  and  Gazette^  collected  from  various  London  and  pro- 
vincial hospitals,  there  was  but  one  case  of  hemorrhage, 
and  in  this  Marshall  Hall's  tracheotome  was  used,  and  a 
vessel  cut,  ending  in  fatal  hemorrhage.  Durham  says  of 
this,  that  it  is  **  an  instrument  which  to  mention  is  to  con- 
demn." 

Regarding  the  thyroid  isthmus,  Trousseau  *  says  :  "  If 
the  isthmus  of  the  thyroid  body  presents  itself  under  your 
bistoury,  never  hesitate  to  divide  it  in  the  mesial  line ; 
there  is  usually  an  arterial  jet  as  large  as  a  thread,  which 
ceases  after  some  seconds,  and  by  this  section  you  have 
signally  facilitated  the  operation."  Of  one  hundred  and 
nine  tracheotomies  for  croup  in  children,  Trousseau  never 
found  it  necessary  to  have  recourse  to  the  ligature  or  tor- 
sion for  a  single  vessel ;  the  hemorrhage  always  ceased 
as  the  canula  was  introduced. 

Holmes,  on  page  323,  says  the  operator  in  trj'ing  to 
insert  the  tube  into  the  trachea  sometimes  "  pushes  the 
canula  down  the  cellular  tissue  in  front  of  the  windpipe, 
causing  pressure  on  the  trachea,  and  obstructing  respira- 
tion still  further."  .  .  .  "The  third  (case)  in  which 
I  have  seen  death  during  the  operation,  the  fatal  event 
seemed  to  me  due  mainly  to  this  error." 

One  of  the  three  fatal  cases  of  Mr.  Holmes,  then,  was 
due  to  what  Trousseau  would  have  termed  a  "  too  nimble 
tracheotomy;"  and  in  another,  death  was  caused  by 
pushing  the  canula  into  the  cellular  tissue  outside  of  the 
trachea,  and  thus  adding  to  the  original  difficulty.  Com- 
ments on  Mr.  Holmes'  tracheotomies  are  unnecessary. 

The  speaker  then  quoted  Professor  S.  D.  Gross  as 
saying  "  the  same  thing"  as  Mr.  Holmes.  In  Professor 
Gross'  "Treatise  on  Foreign  Bodies  in  the  Air-Pas- 
sages," on  page  231,  regarding  tracheotomy  in  children, 
he  says  :  "  I  know  hardly  an  operation  in  all  surgery 
that  I  would  not  rather  undertake  than  this.  .  .  » 
The  amputation  of  a  limb,  the  extirpation  of  a  glandular 
tumor,  lithotomy,  and  even  the  perineal  section  are 
trifling  matters  in  comparison  with  tracheotomy  in  a 

'  St.  Bartholomew's  Hospital  Reports,  vol.  iii.,  p.  334. 

'The  Practitioner,  1869,  vol.  ii.,  p.  212.      *  Trousseau  in  the  Union  M^icale. 


646 


THE   MEDICAL  RECORD. 


[December  13,  1884. 


short,  thick-necked,  and  restive  child."  On  pages  232, 
233  he  says:  "The  isthmus  of  the  thyroid  gland,  even 
when  it  descends  considerably  lower  than  usual,  will 
seldom  embarrass  our  progress ;  should  it  do  so,  it  nmst 
be  held  out  of  the  way,  although  it  has  sometimes  been 
divided  with  impunity/' 

He  adds :  "  Professor  Van  Buren,  of  New  York,  in- 
forms me  that  he  has  completely  divided  this  process  on 
several  occasions  without  the  slightest  loss  of  blood,  mis- 
chief, or  inconvenience."  Even  after  this  Professor 
Gross  says  :  "  Generally,  however,  it  will  be  well  enough 
to  avoid  it  by  holding  it  out  of  harm's  way  ;  should  this, 
however,  be  impracticable,  any  bleeding  that  may  be  ap- 
prehended can  be  effectually  avoided  by  embracing  the 
part  in  two  ligatures,  the  knife  being  afterwards  carried 
between  them."  Here  Professor  Gross's  directions  cer- 
tainly complicate  the  operation  and  prolong  it  unneces- 
sarily. 

He  next  directs  that  the  trachea  be  held  by  a  tenaculum. 
The  operation  is  performed  with  much  more  ease 
and  safety  when  the  trachea  is  grasped  between  the 
thumb  and  index-finger  of  the  left  hand  than  when  held 
by  the  tenaculum.  The  trachea  should  never  be  entered 
without  our  being  guided  by  the  touch.  If  the  windpipe 
is  veiy  deeply  placed,  and  is  not  readily  brought  into 
view,  it  may  be  taken  hold  of  with  the  double  hook  below 
where  it  is  to  be  opened,  and  drawn  upward  and  forward 
until  brought  into  sight.  The  hook  must,  however,  be 
held  by  an  assistant,  and  the  operator  should  keep  his 
thumb  and  finger  on  the  trachea. 

On  page  237  Dr.  Gross  says:  "Great  care  is  to  be 
taken  not  to  permit  any  blood  to  enter  at  the  artificial 
opening,  as  the  smallest  quantity  of  this  fluid  may  not 
pnly  induce  violent  cough  and  spasm,  but  instant  suf- 
focation." Further:  "The  best  plan  to  avoid  this  oc- 
currence is  not  to  injure  any  vessels,  but  to  hold  them 
carefully  out  of  harm's  way;  or,  where  this  is  imprac- 
ticable, to  wait  until  all  hemorrhage  has  ceased  before  we 
penetrate  the  windpipe,'^ 

With  reference  to  the  first  of  these  statements,  it  is 
known  that  the  entrance  into  the  trachea  of  a  small 
quantity  of  blood  is  not  dangerous,  and  many  operators 
purposely  introduce  a  quantity  of  fluid  into  it  to  excite 
cough  in  order  to  expel  mucus  and  membrane.  Bret- 
tonneau  even  recommended  washing  out  the  tube  with  a 
solution  of  nitrate  of  silver.  Next  to  the  hissing  sound 
with  which  the  air  enters  the  opening  in  the  trachea,  one 
of  the  most  striking  things  in  connection  with  tracheot- 
omy is  the  violence  with  which  anything  entering  the 
trachea  is  ejected.  To  wait  until  all  hemorrhage  has 
ceased  before  opening  the  windpipe,  would,  in  many 
cases,  be  to  wait  until  the  patient  is  dead.  The  surest 
way  of  arresting  hemorrhage  is  to  admit  air  freely  to  the 
lungs,  so  as  to  relieve  the  embarrassed  venous  circula- 
tion, and  thus  allow  the  blood  to  return  to  the  heart 
Time  spent  in  trying  to  stanch  the  bleeding  before  open- 
ing the  windpipe  is  generally  to  the  injury  of  the  patient. 
With  reference  to  this  Professor  Gross  himself  says  on 
page  279  :  "  It  is  worthy  of  remark  that,  when  the  hem- 
orrhage is  venous,  it  generally  instantly  ceases,  even 
when  it  is  copious^  the  moment  the  knife  penetrates  the 
windpipe."  And  again  on  page  266  he  says :  "  I  have 
never  experienced  the  slightest  inconvenience  from  any 
occurrence  of  this  kind.  Several  of  my  operations,  in 
fact,  have  been  nearly  bloodless," 

Allow  me  to  turn  back  and  repeat  a  former  quotation 
from  Professor  Gross,  page  231,  in  order  to  make  a  com- 
parison :  "  I  know  hardly  an  operation  in  all  surgery  I 
would  not  rather  undertake  than  this.  .  .  .  The  am- 
putation of  a  limb,  the  extirpation  of  a  glandular  tumor, 
lithotomy,  and  even  the  perineal  section,  are  trifling  mat- 
ters in  comparison  with  tracheotomy."  On  page  373  he 
says :  "  I  am  satisfied,  from  the  facts  before  the  profes- 
sion, that  bronchotomy,  properly  performed,  is,  in  general, 
a  perfectly  safe  procedure,  .  .  .  and  rarely  fol- 
lowed by  fatal  results. " 


Dr.  Gross  in  his  book  does  not  report  a  case  of 
tracheotomy  for  croup.  After  making  a  careful  analysis 
of  Dr.  Gross'  work,  I  am  unwilling  to  accept  his  first 
statement  regarding  the  dangerous  character  of  trache- 
otomy, particularly  when  it  is  made  to  apply  to  the  oper- 
ation in  croup. 

Dr.  A.  Jacobi  was  quoted  as  saying  that  he  never  went 
to  a  tracheotomy  operation  without  a  feeling  of  fear  and 
trembling.  In  the  extensive  writings  of  Dr.  Jacobi  on 
the  subjects  of  diphtheria,  croup,  and  tracheotomy,  I 
fail  to  find  any  statements  which  would  diow  that  he  con- 
siders the  operation  dangerous. 

Now  let  us  review  the  opinions  of  other  authors  : 
Bretonneau,  to  whom  we  are  indebted  for  the  re- 
vival of  tracheotomy  in  the  nineteenth  century,  does  not 
speak  in  any  of  his  five  memoirs  of  the  operation  as  being 
a  dangerous  one,  nor  of  skill  in  its  performance  being  a 
necessity  to  insure  success  ;  his  whole  stress  is  upon  the 
size  of  the  canula,  the  temperature  of  the  air  the  patient 
breathes,  and  the  after-treatment  and  care.  Bretonncan 
was  so  clear  and  decided  in  his  convictions,  which  were 
always  stated  definitely,  that  had'  he  felt  the  operation  lo 
be  a  dangerous  one,  he  certainly  would  have  mentioned 
it  in  one  of  his  several  communications. 

Trousseau,  whose  contributions  on  tracheotomy  have 
never  yet  been  surpassed,  said  :  "  Tracheotomy  in  itself 
is  an  operation  which  is  more  delicate  than  diflBcult ;  it 
requires  only  care  and  presence  of  mind."  He  then  says 
that  he  has  performed  the  operation  "more  than  two 
hundred  times,"  and  adds,  "  I  have  never  had  immediate 
accidents  to  deplore,  except  in  an  adult,  who  died  of 
syncope  at  the  moment  I  made  the  section  of  the  skin.' 
And  again  he  says,  "  I  have  finished  these  operations, 
apparently  so  perilous,  without  fear  and  without  acci- 
dent.'* 

M.  Emangard  *  says  :  "  The  performance  of  this  opetar 
tion  is  exempt  from  all  danger.'' 

Rilliet  and  Barthez  •  say  :  "  The  operation  in  itsdf 
is  not  dangerous." 

Bouchut,  in  1852,  said:  "This  operation  is  of  easy 
execution — it  presents  no  danger  in  itself,  and  if  it  docs 
not  succeed  more  frequently,  it  is  because  the  cases  in 
which  it  is  employed  are  truly  beyond  the  resources  of 
art — the  physician  ought  always  to  be  ready  to  operate.'" 
West  says :  "  It  is  admitted  on  all  hands  that  in  itself 
the  operation  is  not  attended  by  serious  hazard ;  and  the 
uncertainty  as  to  its  issue  depends  not  on  any  defect  in 
the  proceeding.'* 

Meigs  and  Pepper  speak  in  these  terms  :  "7?  m  the 
uniform  testimony  of  those  experienced  in  the  matter, 
that  the  operation  is  in  itself  alone  but  slightly  dangerous 
to  life." 

Vogel  tells  us  that  "the  operation  itself  is  not  at- 
tended by  any  danger  to  life." 

Dr.  R.  M.  Edwards  said  : '  "  The  operation  itself  is  so 
simple  to  a  man  accustomed  to  handle  a  scalpel  and  for- 
ceps, that  it  is  surprising  so  much  has  been  written  aboot 
it,  and  so  many  instruments  devised  to  simplify  its  per- 
formance." 

Dr.  W.  H.  Day,  of  the  Samaritan  Hospital  for  Chil- 
dren, says:  "Tracheotomy  in  itself  is  not  a  dangerous 
operation." 

Mr.  Lawrence  *  says :  "  We  are  fully  justified  in  repre- 
senting the  operation  of  bronchotomy  as  attended  with 
little  pain  and  no  danger."  **  The  operation  itself  is  so 
simple  and  so  easy  that  there  is  very  little  to  be  said  on 
the  mode  of  executing  it." 

Conway  Evans'  says:  "That  tracheotomy  is  in  itself 
a  very  dangerous  operation,  the  tendency  of  all  evidence 
on  the  subject  tends  to  disprove."  He  quotes  fiXMo 
Professor  Gross'  work  to  show  that  the  operation  is  not 
dangerous  ! 

J.   H,  Pooley,  M.D.,  Professor  of  Surgery,  Starlii^ 

>  Les  Annales  de  la  Mtfd.  et  Phys.  Sep.,  x8a7.     *  Dts.  of  Children,  voL  L,  jSu 

*  In  the  Edinburgh  Med.  Journal,  October,  1856,  toL  iL,  part  x,  p.  3x4- 

*  Med.  ChinuT.  Trans,,  vol.  vL     1815. 

*  Edinbuirgh  Med.  Journal,  January,  x86o,  voL  v.,  part  a,  p.  613. 


December  13,  1884.] 


THE  MEDICAL  RECORp. 


647 


Medical  College,'  says:  "The  operation  itself  involves 
very  little  danger  to  life." 

\Vm.  M.  Mastin,*  in  an  article  in  which  he  gives  an 
analysis  of  eight  hundred  and  sixty-three  tracheotomies 
ivhich  he  collected  with  much  care,  says:  **I  cannot 
see  .  .  .  how  any  one  will  venture  to  say  that  trache- 
otomy is/^r  se  of  particular  danger." 

Mr.  Howard  Marsh,*  in  an  article  entitled  "Trache- 
otomy in  Children,  its  Method,  its  Dangers,  and  its 
Difficulties,"  says:  "I  am  convinced  that  tracheotomy 
should  be  regarded  as  a  delicate  operation,  which  re- 
quires coolness  and  caution  in  its  performance,  rather 
than  as  one  that  is  necessarily  either  very  difficult  or  very 
dangerous." 

Robert  Wm.  Parker,  Assistant  Surgeon  of  East  Lon- 
don Hospital  for  Children,  says :  "  By  common  consent 
the  operation  itself  is  not  dangerous,  and  it  hardly,  if  at 
all,  complicates  the  primary  disease  which  calls  for  It." 

Thomas  King  Chambers  said  :  "  Tracheotomy  is  an 
alarming  operation  to  hear  of  or  to  look  at,  but  in  reality 
it  is  not  a  dangerous  one.  ...  Do  not,  therefore, 
alarm  the  patient's  friends  by  speaking  of  it  as  a  *  last 
hope,*.  *a  final  resource,'  or  by  any  similar  weak,  expres- 
sion." 

Let  us  see  what  was  the  verdict  of  the  older  authors 
on  this  operation.  They  always  spoke  from  the  force  of 
their  convictions,  and  in  definite,  unmistakable  terms. 

According  to  Galen,  Asclepiades  first  invented  and 
performed  tracheotomy  in  cases  of  quins}',  about  100 
B.C.  Here  the  term  "quinsy"  relates  to  croup  of  the 
present  day,  for  it  is  described  as  an  affection  which 
"  presents  no  visible  appearance  either  in  the  swallow  or 
in  the  throat,  which,  while  narrowing  the  glottis,  renders 
the  voice  acute,  and  quickly  manifests  symptoms  of 
strangulation." 

Coelius  Aurelanius  says  :  "In  this  manner  he  (As- 
clepiades) saved  a  great  many  persons  who  were  in 
danger  of  perishing  from  suffocation." 

Fabricus,  in  the  sixteenth  century,  said :  **  The  opera- 
tion is  absolutely  free  from  danger.  .  .  .  There  is  no 
part  of  the  least  consequence  exposed  to  injury  in  this 
operation.  ^  Fabricus  is  the  first  who  speaks  of  the  canula. 
Casserius  said  :  "  Those  are  both  ignorant  and  timor- 
ous who  rashly  neglect  this  safe,  easy,  and  often  salutary 
operation.  It  is  easily  performed,  and  cannot  give  rise 
to  danger.  .  .  ,  We  have  nothing  to  fear  from  the  slight 
hemorrhage  caused  by  opening  the  trachea."  Casserius, 
who  introduced  the  curved  canula,  is  the  first  who  men- 
tions the  thyroid  gland  in  speaking  of  the  operation. 

In  1586  Sanctorius  proposed  puncture  of  the  trachea 
with  the  trocar,  which  he  had  invented  for  performing 
abdominal  paracentesis. 

Bartholini  entertained  doubts  respecting  the  use  of^the 
operation  in  quinsy,  especially  in  infants. 

Ren^  Moreau,  in  his  reply,  March  i,  1646,  declared 
that  the  operation  was  neither  difficult  nor  dangerous, 
and  through  his  sound  reasoning  he  served  to  convert 
Bartholin!  to  the  use  of  the  operation. 

In  1695  Dekker  proposed  to  perform  the  operation 
with  a  cutting  trocar. 

Boerhaave,*  in  the  first  part  of  the  eighteenth  century, 
said  :  **  The  windpipe  may  be  divided  without  any  danger 
to  the  patient's  life." 

Detharding,  in  1714,  wrote,  with  reference  to  tracheot- 
omy :  **  The  skin  only  is  divided,  and  a  small  portion  of 
membrane.  There  is  no  ground  for  fear,  even  from  the 
least  dexterous  operator.  No  blood-vessel  from  which 
one  need  fear  hemorrhage,  no  nerve  of  which  the  divis- 
ion can  produce  any  inconvenience." 

Juncker,  in  treating  of  this  operation,  said  :  "  It  does 
not  require  great  dexterity.*'  The  first  vertical  incision 
through  the  cartilages  of  the  trachea  was  made  by  him. 

1  Richmond  and  Louisville  Med.  Journal,  June,  1877,  p.  5x7. 

>  Gaillard's  Med.  Toumal,  January,  1880,  vol.  xxix.,  p.  15. 

>  St.  Bartholomew's  Hospital  Reports,  vol.  iii. 

^Van    Swieten's  Commentaries  upon]  Boerhaave's  Aphorisms,   vd.  viiL,    p. 
Z33.     JSdinburKh.  1776. 


In  1750  Dr.  Lawrence  Heister,*  Professor  of  Physic 
and  Surgery  in  the  University  of  Helmstadt,  wrote  : 
"  This  is  a  safe,  easy,  and  often  salutary  operation.*' 
Heister  was  the  first  to  use  the  word  tracheotomy. 

Louis,  in  the  early  part  of  this  century,  said  :  "  A  little 
consideration  as  to  the  parts  to  be  divided  and  the  mode 
of  doing  it  suffices  to  show  that  the  operation  could  not 
be  attended  with  the  least  danger." 

Mr.  Holmes'  obvious  misconception  regarding  the 
pierformance  of  tracheotomy,  and  the  contradictory  state- 
ments made  by  Gross,  show  sources  of  fallacy  on  their 
part ;  and  this,  with  the  vast  preponderance  of  authori- 
ties against  their  opinion,  wholly  overthrows  it. 

The  operation  of  tracheotomy  not  being  dangerous  in 
itself,  nothing  connected  with  its  mere  performance  should 
influence  the  time  when  it  is  to  be  resorted  to. 

How  does  diphtheria  tend  to  cause  death  when  left  to 
itself?  In  a  very  large  proportion  of  the  fatal  cases,  the 
disease,  in  young  children,  ultimalety  causes  death  by  me- 
chanically obstructing  the  passage  of  air  into  the  lungs. 
The  object  of  tracheotomy  is  to  supply  a  provisional  air- 
passage  in  the  place  of  the  obstructed  rima-glottidis,  so 
as  to  allow  the  disease  to  run  its  full  course,  and  to  gain 
time  for  the  administration  of  remedies ;  and  if  it  ac- 
complish this,  it  should  be  acknowledged,  even  though 
the  patient  should  die  afterward  from  3ie  persistence  of 
the  original  disease,  or  some  of  its  complications.  That 
it  does  accomplish  this  will  be  seen  by  the  mode  of 
death  after  the  operation.  This  depends  very  much 
upon  what  time  in  the  course  of  the  disease  the  opera- 
tion has  been  performed ;  the  type  of  the  disease,  the 
condition  of  the  patient,  and  the  care  with  which  the 
after-treatment  has  been  carried  into  eflfect  When  the 
operation  has  failed  to  save  life,  it  has  been  generally 
either  because  it  was  postponed  until  it  was  too  late, 
until  secondary  complications  in  the  bronchi  and  lungs 
have  arisen,  to  sudden  collapse,  to  the  persistence  and 
extension  of  the  original  disease,  causing  death  by  as- 
thenia or  acute  nephritis  and  uraemia,  or  because  effi- 
cient after-management  and  care  were  wanting.  Sup- 
puration in  the  anterior  mediastinum  (this  generally  may 
be  obviated  by  not  extending  the  superficial  incision  too 
near  the  top  of  the  sternum),  erysipelas  and  gangrene 
around  the  wound,  and  the  slipping  of  the  canula  from 
the  tracheal  opening  have  been  experienced. 

I  wish  you  to  mark  that  none  of  these  causes  of  death 
are  instances  of  failure  of  the  operation  when  properly 
performed,  or  of  its  not  removing  the  main  source  of 
danger  when  the  disease  is  left  to  itself. 

The  only  lesion  that  causes  death,  which  is  directly  due 
to  the  operation  when  properly  performed,  is  ulceration 
of  the  trachea  from  the  mechanical  irritation  of  the  tube. 

Vidand,  in  1854,  and  Goupil,  in  1856,  exhibited  before 
the  Anatomical  Society  of  Paris  two  specimens  of  ulcer- 
ation of  the  trachea  after  tracheotomy,  produced  by  ir- 
ritation of  the  canula. 

In  1859  Barthez  called  attention  to  this  point,  still 
almost  unknown. 

Roger,  in  the  same  year,  in  a  monograph,  published  an 
analysis  of  twenty-one  cases  of  ulceration  of  the  trachea. 

Sanne '  in  his  work  reports  seventeen  cases,  collected 
in  the  service  of  Barthez.  He  says  :  "  More  or  less  red- 
ness of  the  trachea  and  bronchi  have  been  noted  in  eleven 
of  seventeen  cases,  out  of  which  seven  were  accompanied 
with  broncho-pneumonia.  In  one  case  there  was  ab- 
scess of  the  mediastinum,  consecutive  to  a  perforation 
of  the  posterior  wall  of  the  trachea,  and  one  of  oedema 
of  the  glottis." 

In  the  Trans.  Path.  Soc,  London,  vol.  xviii.,  p.  32,  is 
recorded  a  case  of  death  from  pyaemia  after  tracheotomy, 
from  ulceration  caused  by  the  tube.  Two  cases  have  hap- 
pened in  Guy's  Hospital,  in  which  ulceration  extended 
through  the  anterior  wall  of  the  trachea  into  the  innomi- 
nate artery,  and  fatal  hemorrhage  of  course  resulted. 

>  General  System  of  Sui|:ery;  fourth  edition. 

3  Sanu^  :  £tude  sur  le  Croup,  apris  la  Trach^otomie. 


648 


THE  MEDICAL  RECORD. 


[December  13,  1884. 


Mr.  Marsh  reports  two  instances  of  ulceration  of  the 
trachea  out  of  thirteen  operations  in  his  own  experience, 
and  makes  allusion  to  three  others  he  has  been  told  of. 

There  are  many  cases  scattered  through  the  literature 
on  tracheotomy,  but  these  are  sufficient  for  us  to  recog- 
nize its  importance,  its  frequency,  and  the  different  ways 
in  which  it  tends  to  cause  death. 

The  causes  are  the  shape,  the  size,  and  the  length  of 
the  tracheal  tube,  so  that  it  presses  against  the  walls  of 
the  trachea  to  the  extent  of  producing  mechanical  irrita- 
tion and  ulceration. 

Roger  thinks  that  a  small  canula,  by  allowing  of  its 
too  free  movability  and  the  consequent  friction  which 
results  from  it,  can  cause  ulceration. 

The  symptoms  are  expectoration  of  more  or  less  pure 
blood,  along  with  the  sanguinolent  expectoration  com- 
mon to  every  case  of  tracheotomy  for  the  first  few  days, 
in  some  cases  pain  referred  to  the  point  where  the  tube 
impinges  against  the  wall  of  the  trachea,  and  dark  dis- 
coloration of  the  end  of  the  canula. 

The  accident  can  almost  always  be  prevented  by  hav- 
ing the  canula  short,  curved  at  nearly  a  right  angle,  and 
of  proper  size,  so  as  to  fit  quite  accurately  the  calibre  of 
the  trachea,  but  without  making  undue  pressure,  and  hav- 
ing it  freely  movable  on  its  shield,  so  that  it  shifts  with  the 
varying  attitudes  of  the  child.  The  tube  should  be  care- 
fully watched  and  the  trachea  daily  examined  for  indi- 
cations of  irritation,  and  if  detected,  the  tube  must  be 
removed  and  the  opening  in  the  trachea  kept  open  by 
means  of  silver  or  hard-rubber  or  gutta-percha  hooks, 
which  are  held  in  place  by  a  tape  going  around  the 
neck. 

Tracheotomy,  then,  perfectly  accomplishes  its  primary 
object — that  is,  to  overcome  a  positive  mechanical  ob- 
struction in  the  larynx,  and  to  prevent  that  njode  of 
death  by  which  nearly  all  fatal  cases  of  diphtheritic  croup, 
in  which  it  is  not  resorted  to,  terminate,  namely,  death 
by  asphyxia. 

We  will  now  consider 

The  influence  of  the  operation  on  the  original  disease, 
— Sir  James  Paget  *  says :  "1  have  never  seen  the  wound 
become  diphtheritic  after  tracheotomy."  Further  on  he 
says " :  "  I  have  collected  the  particulars  of  upward  of 
one  hundred  and  twenty  cases  in  which  tracheotomy  was 
performed  in  children  suffering  with  diphtheria,  and  in 
none  of  them  was  the  wound  attacked  by  the  disease." 

Mr.  Spence,  in  a  letter  to  Sir  James  Paget,  wrote  :  "  I 
have,  on  several  occasions,  seen  the  wound  affected,  and 
have  known  the  child  die  from  that,  after  the  breathing 
was  free  and  the  tube  removed.*'  He  does  not  in  this 
communication  state,  however,  whether  or  not  the  dis- 
ease had  disappeared  from  the  fauces  ;  in  other  words, 
that  death  was  not  due  to  the  persistence  of  the  original 
disease,  at  its  original  site. 

Mr.  Parker,  of  London,  says  :  "In  my  own  practice 
it  has  only  occurred  twice,  and  on  each  occasion  it  was 
very  slight.  In  one  case,  on  removing  the  tube,  I  found 
the  wound  patched  over  with  little  islands  of  false  mem- 
brane. ...  In  another  case  a  similar  condition  of  the 
wound  was  found." 

Mr.  Howard  Marsh  says  :  "  Diphtheria  of  the  wound 
is  rare.'* 

Trousseau  says  he  has  seen  leech-bites,  slight  cuts, 
blisters,  and  excoriations  and  different  wounds  in  various 
parts  of  the  body  became  diphtheritic,  but  he  does  not 
speak  of  its  c^ccurrence  on  the  tracheal  wound,  which, 
from  his  usual  careful  minute  way  he  surely  would  have 
done  IkmI  he  ever  observed  it. 

Saniic,"  who  was  a  pupil  of  Trousseau,  and  who  bases 
his  c»bscrvati()iis  on  six  hundred  and  sixty-two  operations 
on  croup  by  tracheotomy,  says  in  his  excellent  work  : 
**  Diphiiuria  of  the  wound  is  not  so  frequent  as  you 
might  at  fiist  suppose.    It  seems  that  the  false  membrane 

>  Second  edition  of  his  Clinical  Lectures,  p.  34. 

•  <  )p.  cit..  p.  463. 

*  EcuJe  sur  le  Croup  apr^s  la  Trach^otomie,  par  le  Dr.  Sann^.     Paris,  1869. 


appears  more  readily  on  the  cutaneous  ulcerated  surface, 
or  that  only  deprived  of  its  epidermis,  than  in  a  wound 
which  involves  the  profound  parts.  This  is  so  commonly 
the  case  that  in  diphtheria  of  the  wound  the  lesion  is  first 
to  be  seen  on  the  superficial  parts,  or  edges  of  the  wound, 
where  the  skin  has  been  cut.  It  then  extends  to  the 
neighboring  parts."  ...'*!  will  not  advance,  how- 
ever, that  diphtheria  never  attacks  the  edges  of  the  wound, 
.  .  .  but  I  do  insist  on  this  point,  that  very  often  the 
pellicles  of  the  wound  have  been  confounded  with  plastic 
exudations."  ..."  Diphtheria  of  the  wound  by  it- 
self is  not  very  grave ;  of  all  the  complications  which 
belong  to  the  wound  it  is  the  most  natural,  since  it  is  but 
the  propagation  to  the  exterior  of  the  lesion  which  char- 
acterizes anatomically  the  malady ;  it  has  then  in  a  great 
many  cases  but  a  local  importance." 

I  had  expected  in  examining  the  German  authorities 
to  find  frequent  mention  made  of  diphtheria  of  the  wound, 
on  account  of  their  proneness  to  call  every  wound  on 
which  there  is  an  exudation  diphtheritic.  I  find,  how- 
ever, that  their  references  to  it  are  very  infrequent,  that 
it  is  always  found  to  be  very  slight,  and  does  not  com- 
plicate the  original  disease  or  the  operation,  and  that  it  is 
readily  controlled  by  simple  treatment. 

Dr.  O.  Pinner,*  in  a  report  of  one  hundred  and  thirty- 
seven  cases  of  diphtheria  and  tracheotomy  says  :  "  In  a 
few  cases  diphtheria  of  the  wound  occurred." 

Dr.  Max  Schiiller"  says  in  his  work  :  "As  a  rule  diph- 
theria of  the  wound  may  be  prevented  entirely  by  the 
early  employment  of  damp  carbolic  dressings."  .  - 
"At  any  rate  it  seldom  becomes  necessary  to  employ 
energetic  remedies,  as  diphtheria  of  the  tracheal  wound 
does  well  under  carbolic  treatment." 

Dr.  H.  Lindner  *  says  :  "  Diphtheria  of  the  wound  oc- 
curred in  but  three  of  one  hundred  and  one  cases  operated 
on.  Gauze  compresses  of  carbolic  acid  was  the  only 
measure  taken  to  prevent  its  occurrence." 

We  now  come  to 

The  influence  of  the  operation  on  the  cure  of  croup. 
— The  admission  of  air  into  the  lungs  through  an  artificial 
opening  in  the  windpipe  secures  for  the  diseased  larynx 
entire  rest,  and  this  leads  to  a  suspension  of  diseased 
action  there.  Even  if  the  patient  die  after  the  operation, 
and  we  ^n^^ post-mortem^  that  the  diseased  action  has  not 
ceased  in  the  larynx,  it  is  generally  either  because  the 
operation  has  been  too  long  delayed,  and,  as  a  result, 
death  followed  too  soon  for  any  reparative  process  to 
take  place,  or  to  the  character  of  the  original  disease. 

Mr.  Spence's  communication  to  Sir  James  Paget 
shows  that  the  cure  of  croup  may  be  accomplished  by 
tracheotomy  during  the  persistence  of  the  orginal  dis- 
ease, and  which  afterward  may  destroy  life. 

The  following  cases  from  Sann6's  interesting  work  are 
most  instructive,  and  confirm  the  statement  that  tracheot- 
omy tends  to  the  cure  of  this  very  fatal  complication  : 

Case  IX.,  page  202. — Aged  four  years  ;  operated  on 
in  second  stage  of  croup.  Died  third  day  from  exhaust- 
ion. Autopsy  showed  that  the  larynx  contained  no  false 
membrane. 

Case  XL,  page  208. — Aged  five  years ;  operated  on  in 
third  period.  Died  sixteenth  day.  Larynx  swollen  and 
cedematous,  but  contained  no  false  membrane.  Died  of 
Bright' s  and  pulmonary  complications. 

Case  XIL,  page  213. — Aged  eighteen  months ;  operated 
on  in  third  period.  Died  fourth  day.  No  fsdse  mem- 
brane in  the  larynx.  Bronchi  contained  a  quantity  of 
detritus  and  false  membrane.  Marked  congestion  of  pos- 
terior part  of  the  lungs. 

Case  XI IL,  page  214. — Aged  five  years.  Tracheot- 
omy third  period.  Died  eleventh  day.  No  false  mem- 
brane in  larynx ;  right  lung  healthy ;  left  lung  seat  of 
pneumonia. 

Case  XXVIL,  page  252. — Aged  twenty- three  months ; 

'  Deutsche  Zeitachnft  fiir  Chiruzg.,  B.  »▼.,  P-  304- 

3  Deutsche  Chirurg. :   Prof.  Dr.  Billroth  und  Prof.  Dr.  Leuclce,  L.  37.    Dr- 
Max  SchtiUer  :  Die  Tracheotomie,  etc.,  p.  96.     Stuttgart,  1880. 
■  Deut.  Zeil.  fiir  Chir.,  November  8,  1882,  p.  453. 


December  13,  1884.] 


THE   MEDICAL   RECORD, 


649 


operated  on  in  extremis.     Death  eleventh  day  after  op- 
eration.    No  false  membrane  in  larynx. 

Case  XXVIII.,  page  256. — Aged  two  years;  operated 
second  stage  of  croup.  Died  one  hundred  and  fifty- 
fourth  day.     Nothing  in  larynx. 

In  every  recorded  case  in  which  death  occurred  within 
twenty-four  or  forty-eight  hours  after  the  operation,  false 
membrane  was  found  in  the  larynx  on  autopsy. 

In  "  Guy's  Hospital  Reports,"  Third  Series,  volume 
xxii.,  the  autopsies  in  cases  of  croup  show  the  same  re- 
sults as  those  given  above. 

Some  interesting  cases  bearing  on  this  are  found  in 
The  Medical  Times  and  Gazeite^^  in  an  article  entitled 
<<  Comments  on  Tracheotomy  for  Scald  of  the  Glottis." 
There  were  three  cases  which  ended  in  recovery.  The 
ages  of  the  patients  were  one  year,  two  and  a  half  years, 
and  three  years,  respectively.  "It  would  appear  that 
when  cases  do  well  after  tracheotomy  for  this  accident, 
that  the  restoration  of  a  healthy  condition  of  the  laryngeal 
mucous  membrane  is  rapid.  In  one  case  the  canula  was 
kept  in  place  for  six  days,  in  another  for  five,  and  in  a 
third  for  three." 

The  following  case  from  "  Guy's  Hospital  Reports,"  ^ 
with  remarks  by  Mr.  Howse,  shows  still  more  strongly 
the  value  of  tracheotomy  in  the  cure  of  laryngeal  disease  : 
A  child  aged  twenty-six  months,  with  chronic  laryngitis. 
Breathing  stridulous.  Tracheotomy  performed  by  the 
house  surgeon  October  8th,  died  on  the  night  of  the  12th. 
Autopsy  showed  the  larynx  and  epiglottis  to  be  normal 
in  appearance. 

Remarks  by  Mr.  H.  G.  Howse,  one  of  the  editors  of 
the  "  Reports  : ''  "  The  normal  appearance  of  the 
larynx  is  of  great  interest,  as  it  tends  to  show  that  when 
the  part  is  put  in  a  state  of  perfect  rest  after  a  trache- 
otomy operation,  all  signs  of  inflammation  may  subside 
within  five  days — the  period  which  elapsed  between  the 
operation  and  death." 

The  cure  of  many  cases  of  ulceration  of  the  larynx 
by  tracheotomy,  occurring  in  the  course  of  pulmonary 
phthisis,  and  which  return  after  the  tracheal  opening  is 
allowed  to  close,  but  again  subside  when  the  functions 
of  the  organ  are  once  more  suspended,  might  be  quoted 
if  time  and  space  permitted. 

The  influence  of  tracheotomy  in  arresting  diseased  ac- 
tion in  the  larynx,  leads  us  quite  naturally  to  contem- 
plate the  relation  of  laryngeal  to  laryngo-tracheal  diphthe- 
ria. The  diphtheritic  process  stops  at  the  level  of  the 
vocal  cords  much  more  commonly  than  is  generally  sup- 
posed. That  this  is  true  of  a  large  percentage  of  the 
cases  is  shown  by  some  valuable  autopsies  recorded  by 
Kronlein."  Of  200  autopsies  reported  by  Kronlein, 
in  46  there  was  false  membrane  in  the  larynx  and 
trachea;  and  there  were  164  with  membrane  in  the 
larynx  and  on  the  parts  above,  and  no  membrane  in  the 
trachea. 

When  the  disease  involves  the  trachea  it  is  by  propa- 
gation from  the  larynx^  and  not  by  a  simultaneous  attack 
on  the  larynxy  trachea^  and  bronchi.  In  many  cases  this 
extension  downward  may  be  prevented  by  early  making 
a  way  for  sublaryngeal  respiration,  so  that  the  inflamed 
larynx  may  be  allowed  to  rest  and  be  saved  from  irrita- 
tion by  the  passing  breath,  and  thus  cause  the  arrest  of 
diseased  action  there. 

If  tracheotomy  per  se  is  not  dangerous,  if  it  meet  the 
complication  of  obstruction  of  the  glottis,  and  is  promo- 
tive of  the  cure  of  this  complication  ;  if  the  specific  dis- 
ease is  in  no  way  aggravated  by  it,  and  very  rarely  in- 
deed appear  on  the  wound,  it  certainly  brings  with  it  no 
element  of  added  danger. 

Influence  of  delay, — The  next  consideration  in  de- 
ciding when  to  operate  would  be  the  result  to  the  patient 
of  delay  in  the  performance  of  the  operation.  When 
we  see  that  medicinal  remedies  fail  to  influence  the  arrest 

1  October  aa,  1850,  page  404. 

■  Guy's  Hospital  Reports,  1875,  vol.  xx.,  I^ees  507-8. 

*  Krdnlein  ia  Langenbeck's  Archives  for  Cfiiucal  Surgery,  page  353.    Bertin, 
«77. 


of  croup,  to  relieve,  or  even  to  alleviate  its  symptoms, 
shall  we  trust  to  the  occurrence  of  that  rare  accident,  the 
expulsion  of  the  membrane,  or  shall  we  operate  without 
delay  ? 

As  to  expectoration  of  the  membrane  and  cure  of  the 
disease  without  operation,  Professor  J.  Lewis  Smith 
stated  at  the  March  or  April  meeting  that  about  one  in 
eight  recovered  when  medicinal  treatment  only  was  used. 
Statistics  of  croup  (membranous),  taken  collectively, 
show  that  the  disease  is  fatal  in  about  ninety  per  cent,  ot 
the  total  cases. 

After  tracheotomy  the  recoveries  are  from  one-fourth 
to  one-half.  Trousseau  gives  one-third  in  hospital,  and 
one-half  in  private  practice.  Collected  statistics  from 
English  and  Scotch  hospitals  and  private  practice  show 
that  two-fifths  recover  after  the  operation.*  Sannd ' 
gives  89  operations  by  eleven  different  operators  in  vari- 
ous parts  of  France,  with  39  cures  :  one  cure  in  2.28 
operations.  In  another  table,  39  operations  by  five  oper- 
ators with  17  cures  :  one  cure  in  2.29  operations.  These 
figures  at  once  decide  clearly  the  only  course  to  pursue. 

Does  delay  in  the  performance  of  tracheotomy  com- 
promise its  success  ?  I  cannot  conceive  a  case  where 
delay  would  be  more  dangerous ;  there  is  constant  risk 
of  suffocation,  which  sometimes  comes  on  very  suddenly. 
We  gain  nothing  by  delay,  while  the  success  of  the  op- 
eration is  interfered  with  to  a  great  extent.  When  the 
rima  glottidis  is  obstructed  less  air  enters  the  lungs  with 
every  inspiration,  and  the  lungs  are  less  expanded,  and 
in  proportion  as  the  circulation  of  air  through  these  or: 
gans  becomes  diminished,  the  circulation  of  the  blood 
will  be  embarrassed,  and  this  soon  causes  this  fluid  to  be- 
come vitiated  by  defective  oxygenation.  When  the  op- 
eration is  long  delayed  the  impeded  state  of  respiration 
and  circulation  produce  a  violent  constitutional  disturb- 
ance ;  venous  congestion  has  become  general,  the  veins 
of  the  head  and  neck  are  turgid,  the  entire  body  cyanosed, 
cold,  and  bathed  in  clammy  perspiration,  the  pulse  at 
the  wrist  imperceptible,  the  face  livid  and  ghastly,  the 
child  tossing  in  agony  from  one  position  to  another,  hop- 
ing to  find  relief,  the  inspiratory  muscles,  especially  the 
auxiliaries,  making  violent,  but  fruitless  efforts  to  get 
more  air  through  the  contracted  glottis.  The  vessels  of 
the  bronchial  mucous  membrane  and  the  lungs  become 
passively  distended,  and  a  little  later  serum  infiltrates 
into  the  parenchyma  of  these  organs,  and  the  bronchi 
become  choked  up  with  mucus,  thus  impeding  respira- 
tion still  further.  The  weakened  and  overtaxed  heart, 
with  the  brain,  being  supplied  only  with  venous  blood — 
the  patient,  in  fact,  poisoned  by  his  own  vital  fluid — be- 
comes comatose  or  convulsed,  and  the  sensorial  func- 
tions blunted  and  nearly  destroyed.  Yet  it  is  advised  that 
the  patient  be  allowed  to  reach  this  stage,  that  the  im- 
mediate precursors  of  death  appear,  before  making  an 
opening  in  the  windpipe  to  allow  the  passage  of  air  to 
the  lungs ! 

If  under  these  circumstances  the  operation  fails  to  save 
life,  it  is  spoken  of  as  being  dangerous  and  perilous,  of 
inducing  secondary  complications,  and  similar  absurd  ex- 
pressions ! 

It  would  be  as  rational  to  persist  with  taxis  in  a  stran- 
gulated hernia  until  gangrene  has  set  in,  before  relieving 
the  constriction  with  the  knife,  as  to  continue  medicinal 
treatment  in  a  case  of  obstruction  of  the  glottis  until  the 
patient  has  arrived  at  the  stage  described,  before  making 
an  opening  for  sublaryngeal  respiration.  And  in  the 
same  proportion  that  delay  in  strangulated  hernia  is  dan- 
gerous, so  it  is  in  a  case  of  membranous  obstruction  of 
the  glottis.' 

He  who  has  made  autopsies  in  cases  of  croup  where 
tracheotomy  has  not  been  resorted  to,  and  death  has  oc- 


»  Medical  Times  and  Gazette,  November  25,  1876,  page  600. 

s  Sann^  :  Diphtherie,  page  467.    Paris,  1877. 

*  Justice  to  my  patient,  justice  to  myself,  fidelity  to  die  profession  I  represent, 
all  unite  in  demanding  that  m^tv,  early,  before  the  development  of  conditions  which 
will  make  any  interference  but  a  forlorn  hope,  tracheotomy  should  be  done  I  (L.  S. 
Pilcher,  Proceedings  Kings  County  Society,  Brooklyn,  May,  1877,  p.  8a.) 


650 


THE   MEDICAL   RECORD. 


[December  13,  1884, 


curred  from  asphyxia,  has  seen  that  the  lungs  and  bronchi 
are  in  a  state  of  venous  congestion. 

My  own  records  show  this  invariably.  I  have  examined 
the  records  of  a  large  number  of  autopsies  and  have  found 
that,  where  carefully  made  and  recorded,  the  appearances 
were  quite  uniformly  the  following  : 

First,  /Where  tracheotomy  had  not  been  performed, 
the  lungs  and  bronchi  were  congested,  and  there  was  al- 
ways an  excessive  quantity  of  mucus  on  the  bronchial 
mucous  membrane.  In  a  smaller  number  of  cases,  oede- 
ma of  the  lungs  and  pneumonic  changes. 

Second,  where  tracheotomy  had  been  performed  in 
the  third  stage  of  croup,  and  death  had  followed  soon 
after,  the  post-mortem  appearances  were  much  the  same 
as  in  the  cases  not  operated  on. 

Third,  where  death  had  taken  place  from  several 
days  to  two  or  three  weeks  after  the  operation,  the  mu- 
cous membrane  of  the  bronchi  and  the  pulmonary  vessels 
was  quite  normal. 

Showing  how  quickly  obstruction  to  respiration  may 
induce  changes  in  the  bronchi,  Mr,  Thomas  Bryant  *  re- 
lates the  case  of  a  child  three  years  old,  in  whom  trache- 
otomy was  performed  for  foreign  body,  and  it  could  not 
be  removed.  The  operation  was  performed  one  hour  af- 
ter the  accident.  The  respiration  remained  unaltered, 
and  nine  hours  after  the  operation,  and  ten  after  the  acci- 
dent, the  child  died.  On  autopsy,  the  bronchial  tubes 
were  found  filled  with  tenacious  mucus — in  some  parts 
completely  obstructing  the  passage  of  air  to  the  lungs, 
which  were  airless.  A  piece  of  nutshell  was  found  in  the 
rima  between  the  cords. 

The  condition  of  the  pulmonary  and  bronchial  vessels, 
found  so  constantly  after  death  from  croup,  results  from 
obstruction  in  the  larynx  and  impeded  respiration,  for 
wh^n  diphtheria  exists  in  the  throat  only,  and  there  is  no 
implication  of  the  larynx,  the  disease  tends  to  destroy  life 
by  exhaustion  and  blood-poisoning,  and  rarely  do  any  of 
the  secondary  bronchial  or  pulmonary  complications  occur. 

Where  these  complications  are  found  on  post-mortem 
examination,  after  tracheotomy,  they  are  not  the  result 
of  the  operation,  for  they  seldom  occur  when  tracheotomy 
has  been  performed  on  healthy  organs,  or  in  cases  of 
syphilitic,  and  even  tubercular  laryngeal  disease,  with 
chronic  pulmonary  disease,  and  the  tube  is  worn  for 
months,  and  in  some  instances  for  many  years.  The  re- 
peated performance  of  the  operation  on  the  same  patient 
within  a  short  period,  without  accident  or  complication, 
and  with  ultimate  recovery,  shows  the  utter  harmlessness 
of  tracheotomy,  both  in  its  immediate  effects  and  in  its 
remote  consequences. 

Mr.  Greenfield'  relates  that  tracheotomy  on  a  child 
ten  months  old,  with  croup,  was  repeated  nine  days  after 
the  first  operation,  and  seven  days  after  the  removal  of 
the  tube  by  the  nurse.  During  the  latter  part  of  this 
operation  the  child  appeared  to  be  dead.  Artificial  res- 
piration was  performed  and  the  child  revived.  Recovery 
was  perfect.  Dr.  H.  Z.  Gill '  performed  two  operations 
of  tracheotomy  on  a  boy,  aged  three  years  and  one  month, 
with  croup,  at  an  interval  of  fifty-one  days,  with  ultimate 
recovery.  No  bronchial  or  pulmonary  complications  af- 
ter either  operation.  Pugin  Thornton  *  performed  trache- 
otomy four  times  in  five  years  on  a  man  sixty-seven 
years  old,  with  syphilitic  laryngitis,  without  accident  or 
subsequent  complication,  and  the  case  ended  in  complete 
recovery. 

The  great  reason  why  bronchial  and  pulmonary  com- 
plications follow  tracheotomy  where  it  is  performed  for 
croup  is,  that  where  obstruction  has  continued  a  long 
time  the  lungs  are  in  a  state  of  congestion,  and  in  this 
condition  any  slight  irritating  cause,  such  as  would  act 
harmlessly  on  healthy  lungs,  will  hasten  on  into  a  dan- 
gerous inflammation.  When  it  has  been  decided  that  a 
positive  mechanical   obstruction  to  the  entrance  of  air 


*  British  Medical  Journal,  Februarj"  ^7,  1877,  p.  205. 


into  the  lungs  exists,  do  not  wait  until  lividity  sets  in, 
before  making  a  way  for  free  and  easy  respiration.  Let 
the  operation  be  done  before  secondary  complications 
have  arisen,  or  the  accession  of  those  symptoms  which 
are  in  themselves  extremely  dangerous  to  life,  which 
often  render  all  treatment  unavailing,  and  make  the  re- 
moval of  the  mechanical  obstruction  of  less  importance. 

While  estimating  the  effect  of  protracted  obstruction 
to  respiration  with  the  devitalizing  influence  on  the 
blood  of  the  rapidly  accumulating  carbonic  acid  gas,  its 
depressing  action  on  the  organic  nervous  system  and  on 
the  heart,  we  should  keep  in  view  that  these  combined 
influences  are  promotive  of  the  spread  of  that  depressing 
disease,  diphtheria. 

We  must  also  take  into  consideration  the  life-giving 
and  disease-destroying  power  of  oxygen.     Oxygen  is  the 
most  potent  of  all   tonics,  and  pure,   warm  air  is  the 
most  valuable  remedial   agent  that  we  possess  for  diph- 
theria.    Let  a  child  with  severe  diphtheria  be  kept  liter- 
ally out  of  doors,  in  warm,  dry,  sunny,  summer  weather, 
and  an  almost  immediate  and   uninterrupted  improve- 
ment in  all  the  symptoms  will  be  observed,  both  in  the 
general  condition  and  in   the  local  manifestations.     In 
the  majority  of  cases  of  croup   the  patient  dies    from 
want  of  oxygen  and  exhaustion  of  the  organic  nervous 
system  ;  and  the  object  of  the  tracheotomy  is  to  render 
oxygen  accessible  to  the  child  ;  and  it  should  be  remem- 
bered that  every  draught  of  fresh  air  assists  in  the   pro- 
cess of  cure.     Do  not  wait,  therefore,  until  the  patient's 
strength  is  worn  out  with  gasping  and  fighting  for  breath 
before  granting  him  nature's  sovereign  restorative,  f 

Who  can  watch  a  child  struggling  for  breath  with  all  the 
agony  which  in  consequence  ensues  without  feeling  im- 
pelled to  have  recourse  without  delay  to  the  simple  proced- 
ure of  tracheotomy  ?  Let  those  who  counsel  that  tracheot- 
omy be  the  last  resort  witness  the  extraordinary  relief  which 
follows  it,  how  the  breathing  becomes  tranquil,  easy,  and 
regular,  the  countenance  natural,  the  cold  sweat  ceases, 
the  pulse  is  again  felt  at  the  wrist,  and  perhaps  the  child 
sits  up  and  takes  nourishment,  or  falls  into  a  quiet, 
peaceful  sleep ;  and  I  think  they  will  regret  not  having 
granted  the  child  access  to  air  sooner,  and  lifted  in  one 
instant  an  agony  of  suspense  from  the  parents  ! 

Guersant  ascertained  that  the  resolution  of  pneumonia 
is  facilitated  by  the  greater  freedom  with  which  the  re- 
spiratory functions  are  accomplished  after  tracheotomy. 
But  while  the  symptoms  of  suffocation  and  of  pneumonic 
changes  may  be  relieved  by  the  late  performance  of 
tracheotomy,  they  may  often  be  prevented  by  the  early 
introduction  of  air  into  the  lungs.  It  is  said  that  if  we 
advise  early  operation  we  may  operate  on  many  who 
would  have  recovered  without  resource  to  this  proceed- 
ing ;  and  that  we  may  see  our  patient  recover  after  the 
operation  has  been  rejected  by  the  parents,  but  this  will 
happen  very  rarely  indeed,  and  it  is  better  to  err  on  the 
safe  side,  as  the  operation  can  never  increase  the  danger, 
while  delay  has  many  times  deprived  the  patient  of  that 
chance  of  life  which  the  operation  can  offer. 

Though  there  are,  undoubtedly,  isolated  cases  of  recov- 
ery from  diphtheritic  croup,  the  proportion  of  these  is  so 
small  after  we  are  positive  that  membranous  exudation 
has  invaded  the  larynx,  that  we  ought  to  have  early  re- 
course to  the  only  mode  of  arresting  death  in  the  major- 
ity of  cases. 

It  is  a  far  weightier  responsibility  to  decide  when  to 
operate  than  merely  to  open  the  windpipe.  We  must 
first  determine  the  existence  of  false  membrane  in  the 
larynx. 

Though  recession  of  the  soft  parts  of  the  chest-walls 
with  every  inspiration  is  a  valuable  test  of  the  amount 
of  interference  with  that  act,  it  does  not  necessarily  indi- 
cate the  presence  of  a  pseudo-membrane  in  the  larynx, 
and  it  is  not  a  reliable  guide  if  the  expiration  is  free 
and  easy,  for  these  symptoms  may  be  due  in  great 
part  to  spasm.  The  dyspnoea  due  to  spasm  alone  is 
intermittent   or   remittent,    never   continuous.      But    if 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


651 


there  i»  suppression  of  the  voice,  and  expiration  is  la- 
bored, prolonged,  and  audible,  there  is  no  longer  doubt 
about  the  presence  of  membrane,  for  nothing  but  me- 
chanical obstruction   could   produce   these   symptoms. 
As  soon  as  they  appear,  and  there  are  no  longer  remis- 
sions between  the  croupal  paroxysms,  but  the  dyspnoea 
is  continuous ;   if  insufflations  of  alum,  or  of  alum  and 
sulphur,  with  ipecacuanha  cease  to  afford  relief,  or  emesis 
can  no  longer  be  produced,  and  if  ipecac  only  purges, 
and  poultices  and  steam  have  been  fairly  tried,  it  may  be 
said  that  all  remedial  measures  have  failed  to  control  the 
disease,  and  the  operation  should  at  once  be  performed. 
There  is  nothing  in  the  operation  itself  incompatible  with 
recovery,  even  at  the  early  age  of  six  and  nine  weeks. 
In  1830,  Dr.  Scoutetten,  Professor  of' Surgery,  Military 
Hospital,  Strasburg,   operated  successfully  on  his  own 
child,  six  weeks  old. 

The  diagnosis  of  croup  in  this  case  has  been  ques- 
tioned, but  it  b  stated  in  the  original  report  that  there 
was  expectoration  of  membrane  for  two  days  after  the 
operation. 

In  1880,  Dr.  Steinmeyer*  performed  a  successful  tra- 
cheotomy on  a  child  nine  weeks  old.  I  have  during  this 
research  found  recorded  an  astonishing  number  of  recov- 
eries from  tracheotomy  in  infants  from  a  few  months  to 
two  years  old,  which  shows  that  the  tender  age  of  the 
patient  should  not  be  allowed  to  contra- indicate  trache- 
otomy ;  and  the  recollection  of  these  may  induce  many 
to  perform  the  operation  who  now  oppose  it  on  the 
ground  of  the  early  age  at  which  we  are  frequently  called 
upon  to  have  recourse  to  it  in  many  cases  of  diphtheritic 
aoup. 

In  very  young  children  the  disease  advances  much 
more  rapidly,  and  the  liability  to  bronchial  and  pneu- 
monic complications  is  greater,  and  they  come  on  ear- 
lier in  the  disease  than  they  do  in  older  children, 
therefore  we  should  operate  earlier  in  the  younger. 
In  young  children  the  trachea  is  deeply  imbedded  in 
cellular  tissue  and  fat ;  it  is  small  -and  freely  movable, 
and  the  other  structures  of  the  neck  are  closely  con- 
nected with  it.  Thus  the  operation  presents  difficult- 
Us  which  are  not  met  with  in  older  children. 

Progn4fsis,'^Y^dj\y  age,  previous  ill  health,  especially 
chronic  catarrh,  scrofula,  bronchial  and  chronic  pneu- 
monic changes,  all  make  the  prognosis  more  serious. 
If  scarlet  fever  or  measles  are  prevailing  at  the  time  of 
the  operation,  and  the  patient  has  not  had  them,  he  con- 
tracts them  with  increased  facility,  and  the  prognosis  is 
rendered  very  grave  by  this  added  danger.  Nasal  diph- 
theria makes  the  prognosis  worse  and  severe  epistaxis 
before  or  after  the  operation  is  of  bad  prognostic  omen. 
When  croup  comes  on  very  early  in  the  disease,  and 
makes  its  appearance  very  suddenly,  and  the  obstruction 
is  at  once  extreme,  the  prognosis  is  far  more  serious,  for 
in  such  a  case  the  membranous  exudation  early  tends  to 
spread  into  the  bronchi,  and  even  to  the  alveoli.  When 
the  lymphatics  of  the  neck  are  much  enlarged,  and  the 
neck  greatly  swollen,  the  operation  has  less  chance  of 
success.  The  presence  in  the  urine  of  albumen  and 
casts  make  the  case  more  unfavorable.  When  the 
breathing  is  very  laborious  in  character,  and  the  supra- 
sternal, supra-clavicular,  infra-clavicular,  and  the  scro- 
biculus  cordis  depressions  are  not  marked,  the  prognosis 
is  less  favorable  than  when  recession  at  these  places  is 
very  considerable. 

When  the  bronchi  and  lungs  are  free,  and  the  obstruc- 
tion to  inspiration  is  only  in  the  larynx,  the  recession  of 
the  soft  parts  is  very  great.  Less  marked  depression 
denotes  obstruction  below  the  larynx  and  the  existence 
of  secondary  complications. 

It  is  an  unfavorable  sign  if  the  breathing  does  not 
become  perfectly  free  and  regular  after  the  operation, 
and  indicates  either  the  existence  of  false  membrane 
below  the  tracheal  opening,  or  a  large  quantity  of  mucus 

*  Berlin.  Idinisch.  Wochen.,    No.  46,    1880.     Operation   f<ir  retro- pharyngeal 
abscess. 


in  the  tubes,  or  pneumonic  changes.  Difficulty  in  swal- 
lowing after  the  operation  is  a  bad  symptom.  This  arises 
from  fluids  passing  through  the  glottis,  where  they  excite 
convulsive  coughing  and  escape  through  the  canula. 

After-management. — Success  after  tracheotomy  is  to  be 
obtained  more  by  careful  nursing  than  from  the  perfec- 
tion of  the  operation  itself.  From  careful  observation  I 
am  convinced  that  the  two  main  causes  of  failure  of 
tracheotomy  in  saving  life  are  the  late  performance  of 
the  operation,  and  inefficient  after-care,  and  among  the 
last-named  want  of  proper  attention  to  the  canula.  Olxi 
struction  at  the  inner  end  of  the  tube  from  false  membrane 
or  mucus,  causes  more  deaths  after  tracheotomy,  than 
either  pulmonary  diseases  or  the  original  malady  which 
rendered  the  operation  needful.*  The  physician  should 
not  forget  that  his  whole  duty  is  not  performed  when  the 
operation  is  completed  ;  that  tracheotomy  does  not  tend 
to  cure  the  disease,  but  that  it  allows  time  for  the  applica- 
tion of  the  treatment  found  to  be  most  successful  in 
controlling  it. 

The  sustaining  of  the  patient,  the  administration  of  the 
remedies  for  the  arrest  of  the  disease,  attention  to  meas- 
ures for  subduing  the  local  process  and  reducing  inflam- 
mation, the  temperature,  quality,  and  amount  of  moist- 
ure in  the  air  that  the  patient  breathes,  the  care  of  the 
canula,  and  the  condition  of  the  trachea  and  bronchi 
are  not  generally  carried  out  with  enough  thoroughness  to 
give  the  patient  all  the  advantages  which  the  operation  is 
capable  of  affording. 

I  must  again  revert  to  the  most  important  of  all  the  ques- 
tions just  now  in  connection  with  our  subject — the  danger 
of  the  operation  itself.  The  quotations  from  so  many  emi- 
nent authorities  of  vast  experience  in  the  perfor?rance  of 
tracheotomy  prove  beyond  all  peradventure  that  the  opinion 
that  it  is  a  dangerous  operation  is  erroneous — and  it  is  not 
only  erroneous,  but  dangerous.  To  the  majority  of  people 
in  this  city  the  proposal  of  tracheotomy  seems  equivalent 
to  pronouncing  sentence  of  death ;  and  from  the  opera- 
tion being  represented  as  formidable  comes  the  unwilling- 
ness of  parents  to  consent  to  it  until  the  child  is  about  to 
expire,  and  of  physicians  to  undertake  its  performance. 

In  many  cases  where  tracheotomy  is  required  it  is  as 
much  a  case  of  emergency  as  that  of  a  bleeding  artery. 
When  danger  is  imminent,  an  operation  is  often  needed 
even  without  a  consultation,  and  a  delay  of  a  few  minutes 
might  cost  the  life  of  the  patient ;  but  owing  to  the  prac- 
titioner being  afraid  to  operate,  he  often  leaves  his 
patient  struggling  for  breath  and  rushes  after  a  tracheoto- 
mist  J  and  returns,  perhaps,  to  find  that  his  patient  has 
died  strangulated. 

At  the  March  meeting  one  of  the  speakers  said  that 
he  had  been  summoned  to  half  a  dozen  such  cases,  and 
then,  in  alluding  to  the  danger  of  tracheotomy,  he  stated 
that  he  "  was  willing  to  go  upon  record  as  saying  that 
there  have  been  more  deaths  upon  the  table  in  tracheot- 
omy than  from  any  other  operation  which  is  performed."  * 
From  this  he  inferred  its  danger  !  It  would  have  been 
as  logical  to  have  said  that  tracheotomy  is  dangerous 
because  more  patients  have  died  during  the  delay  at- 
tendant on  the  bringing  of  a  tracheotomist  to  the  patient. 
An  eminent  physician  in  the  early  part  of  this  century 
was  allowed  to  perish  from  this  very  neglect.  Dr. 
Matthew  Baillie  in  the  third  volume  of  the  "  Transactions 
of  the  Society  for  the  Improvement  of  Medical  and  Sur- 
gical Knowledge,"  records  the  fatal  illness  of  Sir  John 
Macnamara  Hayes.  He  was  taken  ill  on  July  i6,  1809. 
His  disease  was  croup.  On  the  night  of  the  i8th  trache- 
otomy was  proposed.  Mr.  Home  and  Mr.  Wilson  were 
sent  for  to  perform  bronchotomy.  Mr.  Wilson  was  out 
of  town,  and  Mr.  Home  did  not  come  until  four  in  the 
morning,  but  the  patient  was  then  in  a  dying  state  ;  he 
expired  at  six.  Autopsy,  20th  :  **  The  cavity  of  the 
glottis  was  found  to  be  almost  obliterated  by  the  thick- 

^  Seventy-eight  per  cent,  die  in  the  first  four  days  (Wanscher).  Seventy-nine 
and  one-half  per  cent,  die  in  the  fiist  tour  days,  and  nearly  sixty-three  per  ceni. 
during  the  first  two  days  (Kronlein,  in  T anfzenbeck's  Archives). 

3  Dr.  Ripley,  Medical  Record,  April  5, 1884,  p.  388. 


652 


THE  MEDICAL   RECORD. 


[December  13,  1884, 


ening  of  the  inner  membrane  of  the  larynx  at  that  part." 
A  prominent  practitioner  in  this  city  left  a  case  of 
diphtheritic  croup  in  the  care  of  a  young  surgeon,  who 
had  been  on  the  surgical  staff  of  Bellevue  Hospital  for 
eighteen  months,  with  the  instruction  that  he  should  go 
for  Dr.  X.  if  he  thought  tracheotomy  necessary.  It  did 
become  so  and  he  obeyed  instructions.  Dr.  X.  not  being 
at  home,  another  surgeon  was  sought  and  found.  The 
trachea  was  opened  immediately,  but  the  child  died  soon 
after  from  exhaustion,  owing  to  the  late  performance  of 
the  operation. 

Contrast  this  absurd  proceeding  with  the  custom  in  the 
hospitals  in  England,  where  nearly  all  the  tracheotomies 
are  performed  by  the  house-surgeons. 

In  this  connection  the  action  of  Professor  J.  G.  Ehr- 
hardt,*  in  the  light  of  a  single  experience  of  the  kind,  is 
interesting  and  instructive  :  "Case  of  diphtheritic  croup, 
summoned  at  2  p.m.,  December  12th,  and  found  child 
much  worse.  Tracheotomy  only  thing  that  offered  benefit. 
Time  was  lost  while  waiting  for  my  father  to  assist  me, 
when  he  arrived  the  boy  was  nearly  dead.  There  were 
two  or  three  respirations  after  the  tube  was  inserted.  I  do 
not  believe  that  the  operation  hastened  death."  "  Decem- 
ber 15th,  called  to  a  boy  of  five  years.  Time  was  too 
precious  to  send  for  a  surgical  assistant ;  operated  at 
once.     Child  recovered." 

The  physician  who  leaves  his  patient  in  a  state  of 
rapidly  advancing  asphyxia  and  goes  in  quest,  perhaps 
in  vain,  of  a  surgeon  merely  to  make  an  opening  in  the 
windpipe,  is  as  culpable  of  neglect  as  he  would  be  if 
he  left  a  spurting  artery  and  went  for  a  surgeon  to  arrest 
the  bleeding.  Another  reason  why  an  exaggeration  of  the 
danger  of  tracheotomy  should  not  prevail  is  that  in  coun- 
try districts  it  almost  entirely  prevents  recourse  to  it.  A 
physician  but  eighty  miles  from  this  city,  who  is  in  the  habit 
of  doing  capital  operations,  has  told  me  that  he  would 
not  dare  to  undertake  tracheotomy,  because  there  is  a 
universal  impression  that  the  operation  is  extremely 
dangerous  to  life. 

I  hope,  as  a  result  of  the  proper  appreciation  of  this 
life-saving  measure,  and  a  thorough  understanding  of  its 
harmlessness,  that  when  diphtheritic  croup  is  epidemic  in 
the  country,  tracheotomy  will  be  as  frequently  performed 
by  the  "family  physician  '*  as  common  bleeding  used  to  be. 

This  misrepresentation  of  the  danger  of  tracheotomy 
has  caused  its  abandonment  several  times  in  its  history. 
After  its  proving  successful  in  the  hands  of  Asclepiades, 
100  B.C.,  from  its  being  scorned  and  being  spoken  of  as  a 
crime  by  Caelius  Aurelanius,  it  was  lost  sight  of  for  more  than 
two  hundred  years,  when  it  was  revived  by  Antyllus  about 
340  A.D.  After  this  the  writings  of  Rhazes,  Avicenna,  and 
others  caused  its  suspension  until  the  time  of  Paulis  -^^ge- 
naeta  in  the  seventh  century,  who  seems  to  have  repeatedly 
opened  the  windpipe.  From  that  date  until  the  attempted 
reintroduction  by  Guieto  de  Cauliaco,  in  the  fourteenth 
century,  we  hear  nothing  of  the  operation.  Brasavola, 
in  the  middle  of  the  sixteenth  century,"  asserts  in  his 
"  Commentaries  "  that  he  himself  opened  the  trachea  in 
a  case  of  a  patient  laboring  under  quinsy,  and  on  the 
point  of  death,  and  thus  saved  his  life,  the  surgeon  not 
daring  to  perform  the  operation.  Dr.  Geo.  Martyn  in 
1730  performed  a  successful  tracheotomy  on  a  young  lad 
with  croup.* 

Dr.  Michaelis  *  in  a  letter  from  New  York,  dated  1 780, 
advised  early  operation  in  these  words  :  "  It  is  unpardon- 
able if  it  is  not  resorted  to  in  time." 

In  1807  Napoleon  offered  a  prize  for  the  best  essay  on 
diphtheria.  The  men  between  whom  the  prize  was 
divided,  and  all  who  were  gathered  at  the  great  medical 
concourse  in  Paris  when  it  was  awarded  in  1808,  were, 
with  one  exception,  opposed  to  tracheotomy.  Caron 
upheld  the  operation  with  great  energy  and  indefatigable 
perseverance.     So  strong  were  his  convictions,  and  so 

1  American  Journal  of  the  Medical  Sciences,  April,  1873,  ?•  43i«  '  1546*    ' 

*  Philosophical  Trans.,  1^30.     Ix>ndon,  1809. 

*  Richtcr's  Chimrg.  Biblioth.,  vol.  vi.,  p.  120.     \oss  :   N.  Y.  Joum.  Med.,  Jan- 
uary, z86o,  p.  31. 


great  his  ardor,  that  he  oflfered  a  prize  of  a  thousand 
francs  to  the  man  who  would  cure  croup  with  the  aid  of 
this  operation.  But  the  opinion  of  the  judges  and  the 
writers  of  the  prize  essays  so  influenced  men  that  there 
was  no  advance  made  in  tracheotomy  until  Bretonneau. 
It  was  given  to  Bretonneau  to  restore  a  supreme  resource 
so  unjustly  condemned.  Four  consecutive  reverses  did 
not  discourage  him,  and  in  1825  he  had  the  happiness  of 
saving  the  daughter  of  his  best  friend  by  the  operation. 

In  1814  Thomas  Chevalier,'  of  London,  made  a  sue- 
cessful  tracheotomy  in  diphtheritic  croup  in  a  boy  seven 
years  old.  Such,  however,  was  the  opposition  to  and 
dread  of  the  operation,  that'  **in  1820  a  medical  gentk- 
man  of  high  standing  in  this  city  (Edinburgh)  who  was 
anxious  to  afford  relief  to  two  of  his  children  affected  by 
croup  could  not  prevail  upon  any  of  the  principal  surgeons 
to  perform  tracheotomy.  At  his  urgent  request  Dr.  Bryce, 
a  gentleman  in  general  practice,  operated  on  one  of  the 
children  without  ultimate  success,  as  both  of  them  died." 

Though  we  need  not  apprehend  the  abandonment  of 
the  operation  to-day,  an  exaggeration  of  its  dangers 
might  be  the  means  of  its  being  withheld  from  many  who 
could  be  saved  by  it,  or  of  its  not  being  resorted  to  until 
it  is  too  late  to  accomplish  any  good.  Let  not  the  erro- 
neous and  dangerous  opinion  go  forth  from  this  Academy 
that  tracheotomy  is  the  most  dangerous  of  all  surgical 
operations!  The  diffusion  of  this  dictum  emanating 
from  such  a  representative  body  of  medical  men,  will  be 
the  means  of  destroying  far  more  lives  in  a  compara. 
tively  short  period,  than  the  operation  itself  or  anything 
directly  connected  with  its  performance  has  from  the 
time  that  it  was  first  instituted,  more  than  two  thousand 
years  ago.  . 

Conclusions. — Tracheotomy  of  itself,  performed  with 
care,  involves  little  if  any  danger  to  life. 

Accidents  during  the  operation  generally  result  from 
want  of  care. 

It  prevents  asphyxia,  and  thus  gives  more  time  for  the 
administration  of  remedies,  and  for  the  system  ultimately 
to  throw  off  the  disease. 

It  prevents  laborious  and  rapid  breathing  and  lessens 
exhaustion. 

It  allows  a  free  supply  of  air,  and  thus  assists  in  the 
cure  of  the  original  malady. 

It  is  the  supreme  resource,  and  as  the  patient  cannot 
be  made  worse  by  it,  do  not  postpone  it  until  there  is  but 
a  forlorn  hope  even  from  it. 

Persistence  of  the  original  disease,  delay  in  the  per- 
formance  of  the  operation,  and  neglect  after,  are  the 
causes  of  its  failure. 

Operate  early,  very  slowly,  deliberately,' carefully,  and 
without  hurry. 

It  is  never  too  late  to  operate  :  even  though  the  child 
has  stopped  breathing,  if  life  is  not  extinct,  open  the 
windpipe  and  perform  artificial  respiration— many  chil- 
dren have  been  saved  under  just  such  conditions.    C, 

If  strangulation  is  the  main  symptom  neither  age,  con- 
stitutional condition,  nor  complications  can  furnish  a 
contraindication  to  its  performance. 

It  alleviates  suffering. 

It  mitigates  all  the  symptoms. 

It  obviates  secondary  complications. 

It  never  adds  one  element  of  dangerjo  the  original 
disease. 

Statistics  taken  collectively  show  that  nine-tenths  of 
the  cases  which  render  the  operation  needful  will  suffotaie 
without  it. 

Performed  early  it  snatches  from  certain  death  fully 
two-fifths  of  all  the  cases. 

No  patient  that  dies  after  the  operation  would  have 
lived  if  it  had  not  been  performed. 

When  it  fails  to  save  life  the  relief  afforded  and  tjie  sub- 
stitution  for  the  most  agonizing  mode  of  death — strangular 


»  Med.  Chimrg.  Trans.,  1815,  vol.  vi.,  p.  150.  This  operation,  though  attributed 
to  Mr.  Chevalier,  was  done  by  Mr.  Lighifoot,  the  house  surgeon. 
*  James  Spence  at  the  Forty-third  meeting  of  the  British  Medical  Asflodation. 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


653 


tion — one  of  the  least,  by  asthenia,  are  sufficient  reasons 
to  justify  its  performance. 

The  dictates  of  science,  facts,  and  common  humanity, 
unite  in  demanding  it. 

Sevcrinus  must  have  been  inspired  when  in  the  seven- 
teenth century  he  said  of  it :  "  It  is  a  divine  invention." 

Allow  me  one  nure  quotation,  gentlemen.  In  The 
Medical  Recoud  of  June  28, 1884,  Professor  Letamendi 
says :  "  In  the  days  of  more  knowledge  and  less  nonsense, 
tracheotomy  will  be  ranked  among  the  minor  surgical 
operations." 

Successful  Tracheotomies  for    Croup  in  Children  One 
Year  of  Age  and  Under, 


%  >Age.|      Disease. 

,Wki 
J    6     Croup. 

.Mos.i 

2  I  3     Croup. 

I 

3  6>^  Croup. 
^  '  7     Croup. 

5 


Operator. 


iScoutetten  (1830), 

;Annandale.> 

ijos.  Ben. 
Tait 


7     Croup. 
7     Croup. 


I  >  Lindner. 


7     Croup.         iWegner. 


Authority. 


7     Croup. 

L 
7>^Croup. 


Kronlein. 
Jos.  Bell.« 


8     Croup.         lElias. 


10 
zi 

14  10     DiphUieria. 


xo     Croup.  "•,! 


10    ICroup. 
10     Croup. 


23 


10  Croup. 

11  iCroisp. 

n  Crotip. 

I 

II  'Croup. 

II  Croup. 

n  Croup. 


12    ,*Croup. 


Croup. 
Croup. 


Day. 

Baizeau, 

V.  Winiwarter.* 

Elias. 

Bourdillat. 

Geo.  F.  Shrady.* 

Trousseau. 

Rauchfuss. 

J.  Cooper  Forster. 

Derby. 

Lindner. 

Tr  endelenbu  rg. 

A.  T.  Woodward. 


Soc.    Med.  des  Hdp.  de 
Paris,  1867. 

Ed.  Med.  Jour.,   vol  vii., 

part   2,  June,  1862,    p. 

iiai. 
Bell :  Letter  to  Brit.  Med. 

Jour.,  April  8,  1871. 
Brit  Med.  Jour.,  April  15, 

1871.  p.  391- 
Deutsche     Zeitschrift     f, 

Chir,  Band  xvii.,  Heft 

S  und  6. ., 

Kronlein:  Archiv  f.  klin. 

Chir,  vol.  xxi.,  1877. 
Rauchfuss    in  Gerhardt's 

Handb.  Kind.,  vol.   iij., 

p.  ao2. 
Syme :   Ed.  Med.    Jour., 

vol.  vl,  part  2,  April, 

1 861,  p.  9561 
Deutsche  Med.  Wochen., 

November  9,  1878. 
Greenfield  in  St.  Thomas' 

Hosp.  Rep.,  vol.  viii.,  p. 

263. 
Gaz.  des  Hdpitauz,  1867, 


P-397. 
ahrl     " 


24  |i2    .Croup.        .Dujardin. 


From  One  to  Two 


25  13  Croup. 

I  i 

26  13  Croup. 

27  13  Croup. 

28  |i3  'Croup. 


Wardner. 

Barthez. 
Trousseau.* 

Archambault. 


Jahrbuch  £  Kind.,  3  u.  4, 

p.  337.  1876. 
Deutsche    Med.    Woch.. 

November  9,  1878. 
L*  Union  M^d,  1872,  vol 

xiii.,  3d  series,  p.  826. 
N.  Y.  Med.  Record,  vol. 

xxii..  Nov.  4, 1882,  p.  512. 
Paris  Theses,  1834,  vol.  x.. 

No.  289,  p.  13,  Aussan- 

don's  Thesis. 
Gerhardt's  Handb.  Kind., 

vol.  iii. ,  p.  202. 
Brit.  Med.  Jour.,  March 

25,  1871,  p.  309. 
Stevens :  Boston  Med.  & 

Surg.  Jour.,  vol.    Ixxi., 

October,  1869,  p.  167. 
Deutsche   Zeit.    £   Chir.. 

Band  xvii.,  Heft  $  u.  6. 
Gerhardt's  Hand.   Kind., 

voL  vi.,  p.  262. 
Mastin:    Gaillard's  Med. 

Jour.,  January  1880,  p, 

L'union  M6d.,   1872,  3d 
series,  voL  xiv.,  p.  46. 


Years  of  Age,  ^ 

fiLounsbury  and  Gill:  IlL 

State  Med.  Soc.  Trans., 

1878,  p.  164. 
Mastin:    Gaillard    Jour., 

January,  1880,  p.  3a 
Gaz.    Hebdom.,   1862,  p. 

806. 
Jour,    des    Conn.   Med.- 

Chirurg.  .September  3d, 

t.  ii.,  p.  I. 
Gaz.  des  H6pitaux,  1867, 

p.  397. 


*  Qiild  lived  seven  weeki  after  the  operation.    On  autopsy  lungs  were  found  to 

be  perfectly  healthy. 

^Communication  to  Med.  Chirurj?.    Society,    Edinburgh.      Professor  Syme 
I  ttooght  that  the  operation  would  not  do  any  good  in  this  case,  but  yielded  to  Bell, 

Ifae  house-surgeon,  who  did  the  tracheotomy,  which  was  followed  by  instant  relief 
;  tothechild.  y»  J 

'  Respiration  stopped  and  artificial  respiration  was  performed  for  ten  minutes, 

Ud  haul  to  be  resorted  to  three  times  within  the  first  hour. 

;:  *  Thb  is  the  youngest  successful  case  operated  upon  in  this  country.     This 

2>peration  was  perfom^ed  between  the  tenth  and  eleventh  month.    Child  is  still 

u^^g.  •  Operation  same  year  as  reported. 


I  Age.      Disease. 


Operator. 


Authority. 


jMos. 
29  '14     Croup. 


30  14 

31 

32 


Croup. 
14  Croup. 
14K  Croup. 


33  IS 

34  IS 

35  lis 
36|iS 
37;i6 
38!i6 

39  117 

40  17 

41  '18 

42  18 

43  ^18 

44  18 

45  18 

46  18 
47;i8 

48  18 

49  ii8 

50  ;i8 

51  ji8 

S3  J19 

S4|I9 

55  19 

56  19 
57|i9 

I 

58  '19 


'Croup. 
Croup. 
Croup. 
I  Croup. 
Croup. 
Croup. 
Croup*. 
Croup. 


!Cabot.» 

I 

'V.  Langenbeclc 

I 

Rapin. 

: Millard  et  H^mey. 

I 
I 
I  Cabot. 

miie. 

Baizeau. 

Isambert. 

Lindner. 

I 

,Wegner. 

I  Nathan  Jacobson. 

Vigla. 


Diphtheria.  Bartscher. 


Croup. 
Croup. 
Croup. 


^C.  Withusen.' 


Diphtheria.  I  Josef  Pauley. 

I 

Croup.  George  Rachel. 

Croup.         Collins. 
;  ] 

Diphtheria.  I  Voigt 


Croup. 

Croup. 

Croup. 

Croup. 

Croup. 

Croup. 
Croup. 


Croup. 
Croup. 


'  Moutard-Martin. 

I 

I  Potain. 

I  Archambault. 

I  Roger.        , 

iPancoast. 

I 

Bose. 

Weber. 


59 


60  ;ao 


61 


62  21 

64  J22 

65  I22 

66  22 

67  |2a 


Croup. 
Croup. 
Croup. 

i 

Croup. 
Croup. 

Croup. 
Croup. 

Croup. 
Croup. 


68  1 22    I  Croup. 
I        I 

69  22     Croup. 


lCr<Mip. 
Croup. 


70  23 

71  '2a 


72  22 

73  22 

74  23 
75,23 
76  23 


I  Croup. 
I  Croup. 
Croup. 
Croup. 
Croup. 


,Wegner. 
[Trendelenburg. 


Jennings. 
!Busch. 

Bose. 

Fitzau. 

I 

,  Kronlein. 
It.  Sendler. 

[  Dower.  < 

I  Isambert. 
Gushing. 

I  Laborde. 

Maslieurat-Lag^mard. 

Ferraux. 
Ijohnson. 

I 

'Wegner. 

'Laborde. 

Trousseau. 

Bose. 

Burland. 


Haywood:    Boston   Med. 

I  and  Surg.  Jour.,  voL 
Ixii.,  p.  273,  i86o. 

KrSnlein :   Archiv  f.  kKo. 

I     Chir..  vol.  xxi.,  1877. 

Sann6  :  Trait6  de  la  Diph- 
theric, p.  481,  Paris,  1877. 

Sann4 :  op.  cit.,  p.  481. 
Jour.  deTherapeutique^ 
1874. 

Boston  Med.  Jind  Surg. 
Jour.,  vol.  Ixx.,  p.  61. 

:Gaz.  des  H6pitaux,  1867^ 

p.  397. 
I  Gaz.  des  H6pitaux,  p.  397, 
i     1867. 

Clinique  Med.,  vol.  i.,  p. 
I    452. 

Deutsche    Zeit  f.   Chir.^ 
I     Band  xvii.,  Heft  5  u.  6. 
'Kronlein:   Archiv  f.  klin. 

Chir.,  vol.  xxi.,  1877. 
N.  Y.  Med.  Record,  June 

30,  1883,  p.  705. 
Gaz.  des  H6pitaux,  1867; 

p.  397- 
Deutsche  Med.  WocRwn-, 
I     1880,  p.  29. 
1  Dub.  Med.  Press,  April  5, 

1865,  p.  320,  from  Uges- 
,  krift  for  Larger,  March. 
!     16,  1865. 

I  Berlin,     klin.      Wochen- 
I     schrift,     February     25^ 
I     1878,  p.  105-6. 
Amer.    Jour.     Med.     Sci- 
I     ences,  July,  1877,  P-  95- 
.Mastin:   Gaillard's    Med. 
I     Jour.,  voL    xxix.,  p.  30^ 
I     January,  1880. 
I  Jahrbuch   f.    Kind.,    voL 
j     viii.,  p.  121,  1882. 
Gaz.   des  H6p.,   1867,  p.. 

I     397. 

Gaz.  des   Hi6p...  1867.   p. 

!    397 

jGaz.    des   H5p.,    1867,  p. 

I    397. 

;Gaz.  des  H6p.,  1867,   p. 

Meigs  r  Amer.  J  our.  Med. 

Sciences,  April,  1849^ 
Kronlein  :    Op.  cit. 
Zeitschrift  f.  Ration.  Med. 

Neue  Folgei,Band  iii-^ 
I     Heft  I,  p.  8,  1852. 
I  Kronlein  :  Op.  cit. 
■Vaneschi:    Berliner  klin. 
j     Woch.,  April,  1872,  p. 

i     163- 

'Archives    of     Pediatrics, 

I     vol.   i. ,  No.  9,  Sept  1$^ 

I     1884,  p.  546. 

Vaneschi :    Berliner  klin. 

Woch.,  April,   1872,  p. 

163. 
Vaneschi :    Berliner  klin. 

Woch.»  April,  1872,  p. 

16^. 
Berliner    klm.     WGcheB<- 

schrift,  April  25, 1879,  p. 

223. 
Krdnlein :  Op.  cit 
Vierteljahrschrift  f.  Prak. 
I     Heil.,  vol  iv.,  p.  71. 
'Brandt:  N.  Y.  Med.  Rec- 
,    ord.  January  13,   1883,. 

I    P«  54* 

Sann6  :  Diph. ,  p.  481. 

Pacific  Med.  and  Surg. 
Jour. ,  vol.  vii. ,  p.  14. 

Gaz.  Hebdonv,  1862,  p^ 
807. 

Gaz.  Med.  de  Paris,  1841^ 
p.  380 ;  1842,  p.  170. 

Gaz.  Hebdom.,  1862,  p.807' 

mi.      State     Med.     Soc. 

I  Trans.,  1879,  P-  120 ;  re- 
ported by  Gill. 

I  Kronlein  :  Op.  cit 

Sann6  :  Diph. ,  p.  481. 

|Sann6:  Diph.,  p.  481. 

Kronlein  :  Op.  cit. 

Gaz.  Hebd..  1862,  p.  808. 


Yrs. 
771  -2 
78: 

79  I  1-2 
80. 


Cases  Exact  Ages  not  Given, 


Croup. 
j-  Croup. 


Krackowizer. 
Korte  (three  cases). 


Jacobi:  Am.  Jour.   Ob.,. 

May,  1868. 
Arch,     fur    klin.     Chir.,. 

Band  xxv.,  p.  820. 


1  Child  had  double  pneumonia  and  recovered. 

*  One  case  died  on'eighly-first  day  of  exhaustion  from  diarrhoea. 


654 


THE   MEDICAL  RECORD. 


[December  13,  1884. 


COCAINE  IN  INTRA-NASAL  SURGERY. 
By  WILLIAM  CHAPMAN  JARVIS,  M.D., 

LRCraRBK  ON   LARYNGOLOGY  IN  THE  NKW  YORK   UNIVERSITY  MEDICAL  COLLEGE. 

On  the  receipt  of  the  intelligence  of  KoUer*s  experi- 
ments *  with  cocaine,  through  Dr.  Noyes*  communication 
to  The  Medical  Record,  the  first  thought  was  naturally 
one  suggestive  of  startling  possibilities  corresponding  in 
direction  with  the  reader's  line  of  inquiry.  In  response 
to  this  impulse  I  have  conducted  a  series  of  experiments 
with  the  new  anaesthetic  in  operations  upon  the  nares, 
and  in  view  of  the  remarkable  and  positive  character  of 
the  results  obtained  feel  encouraged  to  relate  my  experi- 
ence, with  certain  additional  corroborative  testimony. 

My  first  experiments,  conducted  several  weeks  since 
with  a  two  per  cent,  solution  of  the  salt,  were  not  ex- 
tended on  account  of  the  unfavorable  impression  received. 
Though  sceptical  regarding  the  action  of  this  solution 
for  my  purposes,  I  was  nevertheless  inclined  to  expect 
better  results  from  a  stronger  preparation.  A  four  per 
cent,  solution  of  the  crystalline  hydrochlorate  of  cocaine 
was  afterward  obtained  from  a  diflfereut  source.  My 
method  of  applying  the  salt  consisted  in  placing  pledgets 
of  absorbent  cotton  in  contact  with  the  structures  requir- 
ing removal,  and  projecting  upon  them,  by  means  of  a  glass 
lube,  from  five  to  ten  drops  of  the  cocaine  fluid.  The 
cotton  once  moistened  can  be  used  several  times  at  a 
single  silting ;  indeed  cotton  saturated  with  the  fluid  and 
afterward  dried  will  remain  cocainized  for  many  hours.  I 
employ  an  exceedingly  fine  home-made  spray  to  produce 
more  extensive  effects. 

The  cases  reported  have  been  selected  on  account  of 
the  exaggerated  sensibility  of  the  structures  involved,  and 
as  such  offer  excellent  evidence  of  the  powerful  analgesic 
action  of  cocaine. 

Mr. ,  banker,  consulted  me  on  account  of  an  an- 
noying nasal  catarrh.  Examination  revealed,  among 
other  things,  a  deviated  septum  pressing  against  a  con- 
gestive hypertrophy  of  the  left  antero-inferior  turbinated 
tissues.  The  deviated  cartilage  extended  as  a  narrow 
horizontal  ledge  to  the  osseous  edge  of  the  septum,  and 
obstructed  nasal  respiration  through  the  left  nostril. 
While  employing  a  probe  to  point  out  the  site  of  the  af- 
fection, it  happened  to  lightly  touch  the  septum.  The 
patient  started  as  if  severely  injured,  and  invariably  ex- 
hibited signs  of  intense  discomfort.  When  the  manipu- 
lation was  repeated,  intense  sensitiveness  was  exhibited, 
and  my  prospects  of  assistance  from  the  patient  in  a  delib- 
erate operation  could  hardly  have  been  less  favorable.  A 
pledget  of  absorbent  cotton  was  inserted  in  the  nostril, 
against  the  abnormal  structures,  and  a  few  drops  of  the  co- 
caine fluid  placed  upon  it  by  means  of  a  camel's  hair  bmsh. 
At  the  expiration  of  twenty  minutes  the  cotton  was  re- 
moved. The  first  effect  observed  was  the  retreat  of  the 
lower  turbinated  tissue  from  contact  with  the  septum, 
thus  aflbrding  more  room  for  operative  manipulation. 
This  peculiar  action  of  the  cocaine  has  already  been  de- 
scribed by  Dr.  Bosworth.  I  tentatively  nipped  off  a 
piece  of  the  septum  with  my  fenestrated  cartilage  forceps  ; 
the  procedure,  according  to  the  patient's  statement,  was 
perfectly  painless.  Emboldened  by  this  I  commenced 
work  in  earnest,  the  slight  amount  of  bleeding  enabling 
me  to  continue  operating  uninterruptedly  for  five  min- 
utes. During  this  interval  the  patient  declarq^  there 
was  an  entire  absence  of  sensation.  The  parts  were 
then  cleansed  of  tissue  debris.  In  five  minutes  sensation 
had  returned.  I  reapplied  the  cocainized  cotton,  and 
after  leaving  it  in  five  minutes,  proceeded  with  the  op- 
eration. In  this  interval  I  removed  the  whole  length  of 
the  remaining  deviated  cartilage.  The  patient  could 
with  difficulty  find  words  to  express  his  profound  sense  of 
satisfaction. 

Amanda  D ,  aged  sixteen,  referred  to  me  by  Dr.  S. 

Hemingway.     Congenital  occlusion  of   the  nares  from 


malformation  of  nasal  and  turbinated  bones.  Bridge  of  the 
nose  almost  entirely  wanting.  Interocular  space  very 
broad,  falling  of  the  lower  jaws,  with  associated  signs  of 
habitual  mouth-breathing.  Both  nostrils  impacted  with 
flesh-like  masses,  having  almost  the  firmness  and  elasticity 
of  rubber.  The  structures  were  jammed  so  tightly  against 
the  wall  of  the  septum  as  to  give  at  first  sight  the  impres- 
sion  of  its  fusion  with  the  cartilage.  The  turbinated  tis- 
sues present  none  of  the  usual  signs  of  hypertrophied 
membrane,  having  the  appearance  of  slightly  congested 
turbinated  tissues,  and  having  only  a  trifling  tendency  to 
retract  when  touched  with  cocaine.  The  tissues  still 
possessed  a  sensibility  evidently  equalling  that  of  the 
normal  erectile  structures.  The  posterior  nares  were 
obstructed.  A  case  of  congenital  stenosis  succcssfuily 
treated  by  me  several  years  since  presented  many  feat- 
ures in  common  with  this  one.* 

I  had  operated  upon  Amanda  D on  a  previous 

occasion,  employing  my  transfixion  needle  and  ^crascur. 
The  child  did  not  possess  a  particle  of  fortitude,  causing 
me  a  great  deal  of  trouble  by  her  persistent  crying,  and 
in  spite  of  every  precaution  for  her  comfort  she  proved  her- 
self to  be  one  of  the  most  intractable  patients  I  ever  had  to 
contend  with.  This  state  of  hyperaesthesia  was  probably 
due  to  the  prolonged  contact  of  these  delicate  tissues 
with  the  septum  narium.  The  case  seemed  an  excellent 
one  for  the  employment  of  cocaine.  I  therefore  placed 
a  pledget  of  absorbent  cotton  in  the  left  nares,  and 
moistened  it  with  a  few  drops  of  the  solution,  carried  into 
the  nostril  upon  a  camel's-hair  brush.  After  the  expira- 
tion of  fifteen  minutes  I  removed  the  cotton,  and  delib- 
erately transfixed  the  pale  tissues,  the  passage  of  the 
needle,  as  stated  by  the  patient,  causing  absolutely  no 
pain.  The  loop  was  likewise  painlessly  introduced,  and 
the  operation  satisfactorily  completed. 

After  an  interval  of  five  days  I  continued  operating,  re- 
plenishing my  cocaine  bottle  from  a  neighboring  druggist. 
The  solution,  though  applied  as  in  the  first  instance,  did 
not  have  the  desired  effect.  I  then  procured  a  fresh  solu- 
tion from  still  another  druggist.  This  fluid  likewise  failed. 
I^ater  in  the  day  I  procured  some  of  the  original  prepa- 
ratioUf  and  found  it  as  effective  as  in  the  first  instance. 
Small  portions  of  the  turbinated  bodies  were  successfully 
removed  by  means  of  the  fenestrated  cartilage  forceps, 
an  expeditious  but  more  painful  and  bloody  method  than 
excision  with  the  wire,  and  therefore  never  employed 
by  me  for  this  purpose.  The  controlling  influence  of  the 
cocaine  over  the  blood  supply  removed  this  objectionable 
feature,  and  furnished  a  clear  field  for  operation.  As 
the  incisions  gradually  included  the  deeper-lying  tissues 
they  became  sensitive,  requiring  fresh  applications  of  the 
cocainized  cotton. 

Mr.  P ,  merchant,  thirty-two  years  of  age,  was  seen 

by  me  in  consultation  with  Dr.  Bellows,  of  Brooklyn.  The 
patient  had  been  unable  to  breathe  through  the  nose  for 
fourteen  months.  The  nostrils  closed  gradually,  the 
right  being  the  first  to  become  involved. 

Dr.  Bellows  informed  me  that  he  had  already  been  in 
the  hands  of  a  physician,  who  employed  the  galvano-cau- 
tery  for  several  weeks.  A  surgical  procedure  of  a  more 
formidable  character  was  next  employed,  the  patient 
emerging  from  etherization  only  to  be  confined  to  the 
house  for  three  weeks  on  account  of  the  severity  of  the 
operation,  and  an  otitis  media  acuta  set  up  by  the  trau- 
matism. After  recovering  from  these  unfortunate  sequela 
his  condition  was  worse  than  before  the  operation.  An 
examination  showed  the  right  nostril  to  be  entirely  oc- 
cluded by  a  combined  deviation  of  the  septum  and  tur- 
binated hypertrophy.  A  very  narrow  chink  in  the  left 
nostril  permitted  the  occasional  entrance  of  a  feeble  cur- 
rent of  air,  enabling  the  patient  to  partially  remove 
pent-up  nasal  secretions.  It  possessed,  however,  very 
little  respiratory  value. 

I  have  been  gradually  clearing  the  nostrils  for  several 


*  Wiener  Medizmische^ochenschrlft,  No.  44,  1884. 


1  Archives  of  Laryngology,  voL  uL,  x888 . 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


655 


weeks,  removing  small  portions  of  the  tissues  in  such 
way  as  not  to  interfere  with  th.e  patient's  business.  Al- 
though the  careful  excision  of  small  portions  of  bone  and 
cartilage  greatly  diminished  his  suffering,  there  were, 
nevertheless,  moments  when  he  complained  severely  of 
the  pain  inflicted  by  the  rongeur  and  cutting  forceps.  I 
employed  cocaine  by  placing  small  bits  of  absorbent 
cotton  in  contact  with  the  already  wounded  and  tender 
surfaces,  and  dropping  the  solution  upon  it  by  means  of 
a  pipette.  In  thirty  minutes  the  pledgets  were  removed 
and  a  tentative  test  made.  Although  the  forceps  inflicted 
pain,  superficial  sensation  was  reduced  to  a  degree  per- 
mitting the  stripping  off  of  membranes  partly  divided  in 
a  previous  operation.  Another  application  of  cocaine 
was  made,  the  cotton  being  again  removed  after  an  inter- 
val of  fifteen  minutes,  I  then  commenced  to  divide  the 
tissues,  and  was  told  to  continue  the  operation,  as  no 
pain  was  inflicted.  I  continued  operating  for  three  min- 
utes, when  the  patient  interrupted  me  while  cutting  away 
the  deeper  structures  over  the  vomer.  In  this  interval 
bone  and  cartilage  were  alike  divided  without  causing 
the  slightest  pain.  This  method  of  alternately  benumb- 
fng  and  cutting  was  continued  for  more  than  two  hours 
and  a  half,  the  patient  being  in  the  best  of  spirits  during 
the  entire  interval.  He  left  the  office  breathing  through 
a  free  opening  into  the  posterior  nares,  and  thoroughly 
convinced  of  the  pain-relieving  properties  of  cocaine. 

The  following  history,  reported  through  the  courtesy  of 
Dr.  William  Vanderpoel,  offers  additional  evidence  in  a 
case  in  -which  my  dcraseur  was   recommended  :    Mrs. 

Annie    M ,  aged  twenty-nine  years  and  six  months, 

pregnant,  presented  herself  at  my  office,  November  3d, 
suffering  from  a  growth  in  the  left  nostril  which  pro- 
truded three-fourths  of  an  inch,  was  about  three-fourths 
of  an  inch  in  diameter,  of  a  dark  red  color,  firm  upon 
pressure,  and  insensible  to  ordinary  manipulation.  Two 
months  previous  she  had  come  to  me,  presenting  a  small 
growth  in  the  left  nostril,  which  had  all  the  characteristics 
of  an  ordinary  gelatinous  polypus.  Under  ordinary  cir- 
cumstances I  should  have  removed  it  at  once  ;  but  con- 
sidering the  fact  that  she  was  then  four  months  pregnant, 
and  had  previously  miscarried  three  times,  in  each  in- 
stance with  profuse  flooding,  I  feared  the  shock  of  an 
operation  and  ordered  a  spray  of  carbolic  solution  (y^), 
under  ^rhich  treatment  the  growth  seemed  to  disappear, 
but  a  month  later  returned. 

Still  fearing  an  operation,  on  November  9th  I  injected 
the  tumor  with  a  few  drops  of  glacial  acetic  acid,  and  also 
gave  the  patient  a  powder,  composed  of  tannin,  to  be 
snuffed  up  the  nostril  as  best  she  could.  On  November 
15th,  there  was  little  improvement,  so  I  decided  upon  an 
operation.  To  lessen  the  pain  and  shock  of  the  operation, 
I  employed  the  muriate  of  cocaine,  two  per  cent,  solu- 
tion, applied  with  a  camel* s-hair  brush,  to  inside  of  the 
nostril,  as  well  a&  the  tumor  would  permit  the  insertion 
of  the  brush. 

I  made  three  applications  at  intervals  of  ten  minutes, 
using  in  all  3  ss.  of  the  solution,  or  about  one  grain  of  co- 
caine muriate.  The  first  application  was  rather  painful 
from  the  contact  of  the  brush,  but  the  subsequent  caused 
no  uneasiness.  The  Jarvis'  snare  was  then  applied  without 
any  discomfort,  and  passed  well  up  to  the  root  of  the 
tumor,  which  seemed  to  have  origin  from  the  middle  tur- 
binated bone.  No  pain  was  experienced  during  the  opera- 
tion, and  after  an  hour  and  a  half  the  tumor  came  away, 
the  patient  not  losing  more  than  a  few  drops  of  blood 
during  the  entire  operation,  and  no  hemorrhage  fol- 
lowed it. 

In  addition  to  the  foregoing  cases  I  have  employed 
cocaine  to  remove  polypi  and  hypertrophied  turbinated 
tissues,  and  have  found  it  useful  to  facilitate  the  prac- 
tice of  posterior  rhinoscopy  and  to  alleviate  pain  in 
the  larynx  and  pharynx.  I  do  not  consider  its  em- 
ployment urgent  in  the  removal  of  polypi  and  tur- 
binated hypertrophies,  since  these  growths,  especially 
the  former,  can  be  in  most  instances  removed  with  little 


or  no  pain  by  means  of  my  nasal  6craseur.  The  time 
required  to  make  the  operation  painless  with  the  snare 
is  necessary  also  to  prevent  the  occurrence  of  annoy- 
ing hemorrhage.  Although  cocaine  at  times  restrains 
bleeding,  its  action  in  this  respect  is  not  necessarily  per- 
manent. I  have  observed  tissues  pale  and  bloodless 
when  divided  under  the  influence  of  cocaine,  bleed  pro- 
fusely as  soon  as  the  effect  wore  oflf.  The  employment 
of  cocaine  in  the  nostril  has  been  referred  to  in  this 
country  by  Bosworth,  Bettman,  Ingals,  Knapp,  Gruen- 
ing,  and  Claiborne. 

It  is  curious  to  note  that  while  Professor  W5hler  and 
Dr.  Niemann  mention  its  effects  upon  the  tongue,  they 
claimed  it  possessed  no  action  upon  the  eye.*  Von 
Anrep  {Archives  fur  Physiologie^  p.  56,  1880)  experi- 
mented upon  himself  by  pencilling  the  tongue  with  a 
weak  solution  of  cocaine,  and  observed  a  loss  of  sensa- 
tion. The  blood-vessels  were  first  constricted,  then  di- 
lated, and  eventually  resumed  their  normal  condition.  It 
was  probably  this  discovery  that  induced  Fauvel  and  other 
European  laryngologists  to  employ  cocaine  in  examina- 
tions of  the  throat.  Although  I  have  only  employed  a 
four  per  cent,  preparation  of  the  salt,  the  experiments  of 
Jelenek'  indicate  an  advantage  to  be  obtained  by  the 
employment  of  stronger  solutions  (twenty  and  thirty  per 
cent,  alcoholic)  of  the  salt.  The  difference  will  prob- 
ably show  itself  in  a  deeper  and  more  rapid  effect.  My 
remarks  upon  cocaine  analgesia  would  be  incomplete 
without  reference  to  another  agent  of  this  kind.  I  al- 
lude to  rhigolene.  Although  no  record  of  its  use  in 
intra-nasal  surgery  has  come  under  my  notice,  rhigolene 
has  yielded  excellent  results  in  my  hands.  For  the  pres- 
ent I  must  content  myself  with  a  brief  account  of  the 
method,  since  a  detailed  description  would  be  foreign  to 
the  subject  of  my  paper. 

This  petroleum  naphtha,  proposed  by  Dr.  H.  J.  Bige- 
low,  of  Boston,  as  a  local  anaesthetic,  boils  at  70®  F., 
and,  in  the  form  of  a  spray,  is  capable  of  reducing  the 
temperature  15®  below  zero.  Rhigolene,  when  applied 
with  a  suitable  atomizing  apparatus,  will  effectually 
freeze  the  tissues  in  less  than  a  minute. 

I  make  use  of  a  special  contrivance  for  this  purpose. 
Its  action  is  more  prompt  and  deeper,  but  of  shorter 
duration  than  that  of  cocaine.  Cartilage  and  mucous 
membrane  can  be  deeply  and  freely  divided  without 
pain  or  hemorrhage.  The  rapid  disappearance  of  the 
artificial  congelation  makes  it  necessary  for  the  operator 
to  act  with  promptness  and  energy.  In  cases  requiring 
extensive  operative  interference,  frequently  repeated  ap- 
plications of  the  rhigolene  spray  are  necessary.  This, 
however,  does  not  apply  to  the  practice  of  6crasement. 
Tissues  properly  snared  with  the  wire  loop  of  my  nasal 
^raseur  can  be  continuously  frozen  and  divided.  I 
have  utilized  partial  cocaine  anaesthesia  to  facilitate 
transfixion  and  snaring  of  the  turbinated  tissues,  rapidly 
completing  the  operation  with  the  rhigolene  spray.  It 
is  hardly  necessary  to  add  that  daylight  must  be  em- 
ployed for  illumination,  on  account  of  the  inflammability 
of  the  naphtha  fumes. 

Rhigolene  acts  more  rapidly  than  ether,  and  for  this 
and  other  reasons  is  to  be  preferred.' 

Conclusions. — i.  Cocaine  is  useful  in  intra-nasal  sur- 
gery, as  a  local  anaesthetic,  for  the  removal  of  deep  as 
well  as  superficial  tissue  abnormalities. 

2.  Repeated  applications  are  required  for  the  re- 
moval of  the  deeper  structures,  the  time  requisite  for 
anaesthesia  always  being  shorter  after  the  first  effect  has 
been  obtained. 

3.  By  promoting  quiet  and  preventing  secretion,  hem- 
orrhage, and  sneezing,  it  facilitates  the  employment  of 
cutting  instruments  within  the  nasal  cavity. 

4.  The  action  of  cocaine  for  profound  anaesthesia  de- 
pends upon  the  quality  and  quantity  of  the  salt. 

»  American  Journal  of  Pharmacy,  i860,  vol.  xxxit.,  p.  450. 
<  Wienex  Medizinische  Wochenschrift,  No.  45,  1884. 
*  Dictionnaire  de  M^decine,  etc.,  Littr^  and  Kobtn. 


656 


THE   MEDICAL  RECORD. 


[December  13,  1884. 


5.  In  rhigolene  we  possess  a  most  valuable  local  an- 
aesthetic for  intra-nasal  operations,  the  effects  produced 
being  more  rapid  and  complete  but  of  shorter  duration 
than  those  of  cocaine. 

6.  Rhigolene  is  advantageously  employed  in  conjunc- 
tion with  cocaine. 

25  East  Thirty-fikst  Street. 


FURTHER  OBSERVATIONS    ON  THE  USE   OF 
COCAINE. 

.  By  H.  KNAPP,  M.D., 

NEW  YORK. 

Since  my  communication  on  cocaine  and  its  application. 
Medical  RecoRD,  October  25th  of  this  year,  I  have  used 
the  new  anaesthetic  in  a  considerable  number  of  cases,  of 
which  the  following  may  be  of  interest  even  after  the  gal- 
axy of  cocaine  papers  that  have  appeared  in  the  Ameri- 
can and  foreign  press  since  October  i8th. 

Case  I. — Enucleation  of  an  eyeball  under  anasthesia 
from  injecting  cocaine  into  the  post-ocular  cellular  tissue, 
— To-day,  at  my  clinic  at  the  University  Medical  College, 
I  presented  a  patient,  aged  twenty-five  years,  in  whose  left 
eye  I  had  diagnosticated  a  choroidal  sarcoma.  I  stated 
before  the  class  that  it  would  be  quite  an  interesting  ex- 
periment to  inject  cocaine  into  the  orbit,  behind  the  globe, 
and  afterward  test  the  sensibility  of  the  anterior  parts  of 
the  eye,  supplied  by  the  ciliary  nerves.  The  hour,  however, 
drawing  to  a  close,  the  practical  indications  of  the  case 
were  the  only  ones  we  had  time  to  attend  to.  I  instilled  two 
drops  of  a  four  per  cent,  solution  of  Merck's  hydrochlorate 
of  cocaine  into  the  conjunctival  sac.  Five  minutes  later 
another  five  drops  were  instilled,  and  about  six  minims  of 
the  same  solution  injected  behind  the  globe.  This  was 
easily  done  and  not  felt  at  all  by  the  patient.  The  eye- 
ball had  been  forcibly  drawn  toward  the  nose  with  a  pair  of 
fixing  forceps,  the  point  of  the  hypodermic  syringe  thrust 
into  the  orbital  tissue  as  far  as  the  posterior  pole  of  the 
globe.  Five  minutes  later  the  eye  was  enucleated  in  the 
usual  way.  The  patient  indicated  slight  pain  at  the  di- 
vision of  the  tendons  of  the  recti  muscles.  The  division 
of  the  optic  nerve  and  the  dissection  of  the  posterior 
segment  of  the  globe  caused  almost  no  pain.  When  the 
eyeball  was  removed,  I  thrust  the  end  of  the  forceps  an 
inch  deep  into  the  wQund  of  the  orbital  cellular  tissue. 
The  patient  did  not  move,  and  said  she  felt  nothing. 
The  bleeding  was  very  scant.  The  eyeball  was  opened 
at  once,  and  a  typical  melanotic  sarcoma  of  the  choroid, 
the  size  of  a  cherry  pit,  covered  by  detached  retina,  was 
exhibited  to  the  class.  Ten  minutes  later,  when  the 
hemorrhage  had  completely  ceased,  I  united  the  con- 
junctival wound  with  a  continuous  suture.  By  this  time 
the  sensibility  had  returned,  and  the  patient  screamed  at 
every  stitch,  saying  that  this  hurt  her  very  much,  whereas 
during  the  operation  she  had  felt  almost  no  pain. 

This  observation  has  convinced  me  that  even  the  re- 
moval of  the  eyeball  does  not  lie  outside  the  field  of  ap- 
plication of  the  new  local  anaesthetic. 

Case  II. — Ptosis  operation  after  subcutaneous  injection 
of  cocaine  ;  anasthetic  effect  not  very  satisfactory. — A 
boy  aged  about  ten  years,  with  double  congenital  ptosis, 
was  operated  on  at  the  clinic  of  the  University,  Novem- 
ber 25th.  I  injected  a  few  drops  of  a  four  per  cent,  solu- 
tion of  cocaine  under  the  skin  of  the  right  upper  eyelid, 
introducing  the  point  of  the  syringe  3  mm.  above  the 
edge  of  the  lid,  near  the  outer  commissure,  and  advancing 
it  horizontally  nearly  to  the  inner  commissure.  In  with- 
drawing the  needle,  I  injected  the  liquid.  The  lid  swelled 
slightly,  was  suff'used  with  blood,  and  in  ten  minutes 
only  partially  insensible.  I  held  it  compressed  between 
a  clamp,  removed  an  elliptical  piece  of  skin  and  muscle, 
and  stitched  the  lower  lip  of  the  wound  to  the  upper, 
passing  the  sutures  high  up  through  the  skin.  The  tissue 
which  I  removed  was  infiltrated  with  blood.     The  patient 


had  pain  during  the  whole  operation,  not  great  in  the 
centre,  but  quite  keen  at  the  peripheiy  of  the  wound. 
He  was  restless  and  uneasy.  I  etherized  him,  which 
took  about  one  minute,  and  performed  the  same  opera- 
tion on  the  other  eye  under  perfect  anaesthesia.  The 
four  black  silk-sutures  which  loosely  closed  each  wound 
•  were  removed  to-day,  a  week  later,  before  the  class. 
There  was  no  trace  of  suppuration  ;  primary  union  had 
taken  place  in  both  lids,  though  the  wounds  had  been 
protected  by  nothing  more  than  a  clean  handkerchief,  and 
the  boy  had  gone  home  to  Harlem  immediately  after  the 
operation.     The  result  in  both  eyes  is  perfect. 

Case  III. — Perforation  of  drumhead ;  cocaine  anes- 
thetizes the  inner  wall  of  the  drum-cavity^  but  not  the 

drumhead, — Mr.  ^,  aged  twenty-one,  a  student  of 

medicine,  presented  himself  on  October  23d  at  my  of- 
fice, with  a  middle-sized,  clean-cut  perforation  in  cad 
drumhead.  The  drumheads,  as  well  as  the  inner  walls 
of  the  drum-cavity  were  quite  sensitive  to  the  touch  of 
a  probe.  Fifteen  minutes  after  the  instillation  of  coca- 
ine, the  drumheads  had  lost  nothing  of  their  sensibil- 
ity, but  the  inner  walls  of  the  drum-cavity  were  com- 
pletely anaesthetic.  The  patient  felt  a  bitter  taste  in  his 
throat. 

Case  IV. — Cocaine  in  cataract  operations  pre-emi- 
nently useful, — Division  of  primary  and  secondary  cata- 
ract is  entirely  without  pain — a  great  advantage,  for  it  re- 
moves also  the  reflex  contraction  of  the  globe,  which 
favors  too  great  a  capsular  opening  in  soft  cataract,  and 
prolapse  of  vitreous  or  of  shreds  of  capsule  in  secondary 
cataract.  The  perfect  rest  of  the  eyeball  is  highly  favor- 
able for  an  exact  technique. 

In  extraction  of  senile  cataract  under  cocaine,  there  is 
only  one  step  connected  with  pain,  viz.,  the  excision  of 
the  iris.  This  pain  is  commonly  not  great,  and  easily 
borne.  The  perfect  insensibility  of  the  conjunctiva  and 
cornea  insures  the  steadiness  of  the  eyeball,  and  the  cor- 
rect location  of  puncture,  counter-puncture,  and  track  of 
the  section.  The  absence  of  pressure  makes  accidents, 
such  as  falling  of  iris  before  the  knife,  and  prolapse  of 
vitreous,  less  likely  to  occur.  Without  going  into  de- 
tails, I  may  «ay  that  it  assists  the  operator  in  every  step, 
but  particularly  in  the  so-called  toilet  of  the  wound,  1.^., 
its  cleansing  and  final  adjustment. 

The  property  of  cocaine  to  contract  the  blood-vessels, 
which  is  of  great  advantage  in  operating,  has  been  sus- 
pected of  having  bad  after-effects.  Dr.  G.  J.  Ball,  in  the 
New  York  Medical  Journal^  November  22,  1884,  i)age 
587,  makes  the  following  remark  :  **It  became  a  ques- 
tion whether  the  new  anaesthetic  might  not  impair  nutri- 
tion in  certain  operations  in  which  the  slightest  impair- 
ment might  afifect  the  result  injuriously.  In  two  cases  of 
cataract  extraction  in  which  cocaine  was  employed,  the 
operations  had  been  followed  by  sloughing  of  the  flap. 
It  might  be  well  to  consider  whether  this  was  more  than 
a  mere  coincidence."  I  think  it  was  not.  Since  the  in- 
troduction of  cocaine,  fifteen  successive  extractions  have 
been  performed  under  the  influence  of  cocaine  at  the 
New  York  Ophthalmic  and  Aural  Institute.  Only  one 
operation  was  followed  by  some  reaction — it  was  a  com- 
plicated operation.  The  recovery  was  protracted,  but 
good.  The  other  cases  were  free  from  any  disturbance 
both  during  the  operation  and  the  course  of  healing,  and 
the  results  were  good  in  all. 

I  feel  sure  that  in  this,  the  most  important  operation 
in  ophthalmic  surgery,  therate  of  success  will  be  increased 
by  the  introduction  of  the  new  anaesthetic,  through  I>r. 
C.  Koller. 

Dbcbmbbs  9. 1884. 


The  Shortest  Clinical  Report  on  Record.--A 
correspondent  from  Warren,  O.,  would  like  to  hear  from 
the  profession  on  the  following  case :  "  Man — after  swal- 
lowing glass  of  whiskey,  chewed  and  swallowed  part  of 
the  glass."  Correspondent  would  like  to  know  how  it 
should  have  been  treated. 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


657 


[^Xinic^l  gjeparttttjent 


MURIATE   OF  COCAINE   IN   DENTISTRY. 

G.  W.  Weld,  M.D.,  D.T).S.,  of  New  York,  believes 
that  the  best  method  of  application  of  muriate  of  cocaine 
in  the  operation  of  removing  tartar  from  the  teeth,  in 
Rigg's  disease,  is  as  follows  :  Wash  the  gums  with  a  little 
dilute  alcohol,  then  apply,  by  means  of  a  cameFs-hair 
brush,  a  small  quantity  of  a  ten  per  cent,  solution  of  the 
cocaine.  Renew  this  once  or  twice,  when  in  the  course 
of  five  minutes  it  will  be  found  that  there  is  a  marked 
numbness  and  diminution  in  the  sensibility  of  the  gums 
corresponding  to  the  sides  of  the  teeth  on  which  the  ap- 
plication was  made.  The  following  formula  is  recom- 
mended : 

Cocainas  chloridi  (Merck) gr«  vj. 

Spiritus  menthae  piperita 3  j. 

An  exposed  nerve  pulp  was  treated  with  the  above 
solution,  and  partially  extirpated,  without  causing  any  pain 
to  the  patient.  In  the  preparation  of  an  extremely 
sensitive  tooth  for  filling,  a  glycerite,  ninety  per  cent,  in 
strength  (made  by  dissolving  Merck*s  crystals  in  glyce- 
rine) was  allowed  to  remain  in  the  cavity  for  a  period  of 
thirty  minutes.  On  renewing  the  operation  the  patient 
stated  that  the  pain  was  materially  deadened.  The  same 
experiment  was  tried  with  the  borate  of  cocaine  fFoucar's 
crystals),  and  similar  results  apparently  obtainea,  but  the 
paste  was  permitted  to  remain  in  the  cavity  of  the  tooth 
for  twenty-four  hours. 

Dr.  C.  H.[Shears  writes  :  "  I  have  used  cocaine  twice 
in  the  extraction  of  teeth,  and  in  each  case  the  operation 
was  for  a  single  tooth.  The  preparation  used  was  a  two 
per  cent,  solution.  In  the  first  case  the  tooth  was  ex- 
quisitely tender  and  the  gum  inflamed,  and  so  closely  ad- 
herent to  the  tooth  that  it  was  necessary  to  incise  it. 
After  carefully  drying  the  gum,  a  small  camel's  hair-bmsh 
was  dipped  into  the  solution,  and  the  gum  on  either  side 
of  the  tooth  brushed  across  a  few  times.  This  was  re- 
peated twice  at  intervals  of  about  three  minutes,  making 
three  applications  in  all.  A  few  minutes  later  the  gum 
lancet  iwpas  used,  with  almost  no  pain  at  all.  The  tooth 
was  then  extracted  with  a  little  less  pain  than  it  could 
have  been  without  the  anaesthetic.  The  second  case  was 
similar  to  the  first,  and  the  solution  was  applied  in  the 
same  manner,  with  two  additional  'applications.  After 
cleansing  the  incision  from  blood  a  few  drops  of  the  solu- 
tion were  instilled  into  it,  and  repeated  once  after  about 
three  minutes.  No  pain  attended  the  incision,  and  the 
tooth  was  extracted  with  considerably  less  pain  than  in 
the  first  case.*'  • 

W.  P.  HoRTON,  Jr.,  of  Cleveland,  O.,  sends  us  word 
that  he  inserted  a  few  drops  of  the  four  per  cent,  solution 
into  the  cavity  of  a  sensitive  tooth,  and  that  ^a  few 
minutes  afterward  he  used  the  dental  engine  without 
pain. 

Dr.  J.  R.  Uhler,  of  Baltimore,  Md.,  says  that  on 
November  ist,  he  published  some  experiences  with 
muriate  of  cocaine  in  general  surgery.  In  all  cases  it 
produced  more  or  less  superficial  anaesthesia,  but  acted 
better  on  thin  mucous  membranes  than  on  the  unbroken 
skin.  Upon  the  rectum,  when  freely  used,  beside  be- 
numbing the  parts,  it  produced  in  two  cases  a  rigid  tonic 
contraction  of  the  sphincter  ani,  which  had  previously 
been  relaxed,  and  contraction  of  the  longitudinal  fibres 
of  the  gut,  pulling  up  the  mucous  membrane,  which  before 
ha  I  protruded.  So  firm  was  the  contraction  that  the 
sphincter  stood  out  like  a  ring,  and  the  finger  could 
with  diflSculty  be  made  to  enter  it.  For  vaccination  and 
small  operations  upon  the  skin,  the  following  plan  was 
tried  in  two  cases  and  found  satisfactory.  First,  a  few 
drops  of  a  strong  solution  of  the  dnig  were  painted  on  the 
skin  where  it  was  intended  to  be  cut,  and  after  the  lapse 


of  a  few  moments  the  knife,  dipped  in  some  of  the  solu- 
tion, was  passed  gently  over  the  part,  so  as  to  denude 
only  a  few  of  the  outer  cells  of  the  skin/ but  not  penetrat- 
ing;deeply  enough  to  cause  hemorrhage  or  pain.  Over 
this  minute  abrasion  or  cut,  which  was  made  to  allow  the 
drug  to  get  nearer  to  the  nerves,  and  be  absorbed,  some 
more  of  the  solution  was  painted,  and  after  a  short  inter- 
val the  operation  was  proceeded  with,  the  patients  mak- 
ing no  complaints.  Where  mucous  membranes  are  hard 
and  very  thick  it  will  act  slowly  or  imperfectly,  unless 
used  by  hypodermic  injection,  and  anaesthesia  is  most 
plainly  perceived  where  nerves  are  most  thickly  dis- 
tributed. In  a  case  of  labor  reported  in  the  Maryland 
Medical  Journal  I  purposely  avoided  appl)dng  cocaine 
to  the  mouth  of  the  uterus,  as  I  feared  that'^tetanic 
rigidity  of  the  organ  might  be  produced. 


MURIATE     OF    COCAINE     IN     GENERAL 
SURGERY, 

Dr.  J.  W.  Stickler,  of  Orange,  N.  J.,  wishing  to  know 
the  effect  of  cocaine  hydrochlorate  upon  the  skin  and 
underlying  tissues,  had  the  following  experiment  tried 

upon  himself  by  Dr.  T.  Y.  Simpson  :  Dr.  S injected 

with  an  ordinary  hypodermic  syringe,  four  and  one-half 
minims  of  a  four  per  cent,  solution  of  the  alkaloid  under 
the  skin  of  the  fore-arm.  After  the  lapse  of  five  minutes, 
the  point  of  a  knife  was  applied  to  different  parts  of  the 
skin,  immediately  over,  and  adjacent  to,  the  point  of 
puncture,  with  the  following  result :  partial  anaesthesia 
of  the  skin  along  the  line  of  the  injection^  most  marked  at 
the  point  where  the  fluid  was  deposited  in  the  tissues, 
that  is,  at  the  precise  point  where  the  cocaine  was  forced 
from  the  point  of  the  hypodermic  needle.  On  either 
side  of  this  line,  the  partial  anaesthesia  extended  about  one- 
eighth  inch.  As  the  anaesthesia  did  not  become  more  pro- 
nounced after  waiting  another  five  minutes,  a  second 
injection  of  five  minims  was  made.  The  needle  was 
inserted  at  a  point  just  beside,  and  parallel  with,  the  first, 
but  forced  deeper  into  the  tissues  (one  inch).  At  the  end 
of  five  minutes,  the  same  superficial  test  was  applied  as 
in  the  first  instance,  the  face  being  turned  aside  so  as 
not  to  see  the  application  of  the  knife.  Sensation  seemed 
about  normal,  except  in  a  band  of  integument,  nearly 
one  inch  long,  and  half  an  inch  wide,  the  maximum 
superficial  anaesthesia  existing  along  the  line  of  the  open- 
ing made  in  the  tissues  by  the  hypodermic  needle.  The 
hyperaesthetic  line  bounding  the  anaesthetic  area  (referred 
to  by  Dr.  Hepburn  in  Medical  Record,  November  15, 
1884)  I  could  not  define  in  my  own  case,  and  there  did 
not  seem  to  be  increased  sensitiveness  at  any  point  within 
the  limits  of  that  portion  of  the  skin  slightly  congested 
by  the  action  of  the  drug.  After  thirteen  minutes  had 
elapsed  from  the  time  of  puncture,  the  doctor  transfixed 
with  a  surgeon's  needle  the  anaesthetic  skin,  without 
producing  the  slightest  pain.  The  needle  being  with- 
drawn, an  incision  was  slowly  made  with  a  scalpel  through 
the  entire  thickness  of  the  skin  and  cellular  tissue,  pro- 
ducing so  little  sensation  of  any  kind  that,  had  my  atten- 
tion been  otherwise  engaged,  I  doubt  if  I  would  have 
known  that  the  doctor  was  cutting  me.  This  cut  was  made 
along  the  line  of  the  injection,  and  about  corresponded 
in  extent  with  the  length  of  the  hypodermic  needle.  The 
wound  was  left  open  about  four  minutes,  when  a  needle 
was  slowly  introduced,  at  a  point  midway  between  the 
two  extremes  of  the  cut,  into  the  deeper  tissues.  Abso- 
lutely no  sensation  was  experienced  till  the  point  of  the 
needle  entered  the  sheath  of  one  of  the  extensor  muscles. 
That  the  muscle  was  penetrated  was  evident  from  the 
motion  given  the  needle  when  the  muscle  was  exercised. 
The  pain  occasioned  by  contact  of  the  needle  with  the 
muscular  tissue  was  very  slight.  About  five  minutes 
later,  sutures  were  introduced  without  pain,  but  produced 
a  sense  of  pressure  such  as  Dr.  Wright  said  he  felt  when 
a  needle  was  thrust  into  the  skin  of  his  forehead  (Medi- 


658 


THE    MEDICAL  RECORD. 


[December  13,  1884* 


CAL  Record,  November  22,  1884).  The  anaesthesia 
remained  well  pronounced  half  an  hour.  Twenty  minutes 
after  the  second  injection,  there  were  slight  muscular 
tremors ;  other  than  these,  there  were  no  evidences  of 
systemic  disturbance.  It  is  interesting  to  observe  that 
when  tke  hypodermic  needle  is  made  to  traverse  a  direct 
course  through  the  skin  and  cellular  tissue,  the  hydro- 
chlorate  of  cocaine  does  not  diffuse  itself  equally  in  every 
direction,  but  follows  quite  definitely  the  channel  made 
for  it  by  the  needle,  producing  anaesthesia  along  this  line, 
but  to  a  very  limited  extent  on  either  side  of  it.  In 
opening  an  abscess,  or  in  making  any  straight  incision, 
this  circumstance  would  find  a  practical  application.  A 
much  larger  area  of  skin  could  be  rendered  anaesthetic 
by  one  injection,  if  the  cellular  tissue  were  made  more 
permeable  by  moving  the  point  of  the  injecting  needle 
from  side  to  side  after  its  introduction. 


MURIATE  OF  COCAINE  IN  OPERATIVE  GYNE- 

COLOGY— VESICO-VAGINAL  FISTULA. 
Dr.  W.  H.  Doughty,  Jr.,  of  Augusta,  Ga.,  writes :  **The 
peculiar  interest  which  attaches  to  all  reports  upon  the 
use  of  the  hydrochlorate  of  cocaine  leads  me  to  report 
the  following  observations,  made  November  18,  1884,  upon 
its  effects  during  an  operation  for  vesico-vaginal  fistula. 

"  The  fistula  was  a  small  one,  barely  admitting  a  silver 
probe  of  ordinary  size.  The  patient  having  been  placed 
in  the  *knee  and  breast'  posture,  after  thoroughly 
cleansing  the  vaginal  surface  and  roughly  testing  its 
sensitiveness,  two  applications  (two  drops  each)  of  a  two 
per  cent,  solution  of  the  hydrochlorate  of  cocaine  were 
made,  three  minutes  apart.  Two  minutes  later  the  sensi- 
tiveness was  decidedly  lessened,  but  not  enough  for  my 
purpose.  The  solution  was  now  freely  applied  with  a 
brush,  and  five  minutes  later  the  application  was  re- 
peated. After  three  minutes  more  the  anaesthesia  seemed 
to  be  complete. 

**  The  paring  was  made  during  sixteen  minutes  without 
the  slightest  evidence  of  pain,  but  at  the  expiration  of 
this  time  the  patient  complained  and  the  solution  was 
again  applied.  In  thirteen  minutes  more  the  paring  was 
finished  without  pain. 

"  The  patient  having  been  in  the  *  knee  and  breast ' 
posture  for  more  than  a  half-hour,  and  being  now  fatigued, 
was  placed  in  Sims'  position  and  allowed  to  rest  for  a 
few  minutes.  Upon  resuming  the  operation,  the  intro- 
duction of  the  first  two  sutures  was  attended  with  con- 
siderable pain  ;  the  solution  was  therefore  again  applied, 
and  the  remaining  sutures,  four  in  number,  were  intro- 
duced without  pain. 

"The  apparent  effect  of  the  drug  upon  the  hemorrhage 
was  worthy  of  note.  During  the  first  sixteen  minutes  of 
the  paring  there  was  very  slight  oozing,  but  when  the 
sensitiveness  returned  the  loss  of  blood  was  decidedly 
increased  ;  it  diminished  very  much  after  the  solution 
was  reapplied. 

**  The  sponge  was  not  carefully  used  before  making 
the  application  during  the  introduction  of  the  sutures, 
and  the  coagula  which  formed  were  seemingly  firmer  than 
usual  and  rather  difllicult  of  removal  by  sponging. 

"Drs.  T.  R.  Wright  and  J.  M.  Hull,  of  this  city,  were 
present  and  assisted  me." 

MURIATE  OF  COCAINE  IN  IRIDECTOMY— IN- 
JECTION  INTO  THE  ANTERIOR  CHAMBER. 
Dr.  Eugene  Smith,  of  Detroit,  Mich.,  writes :  **  Hav- 
ing, during  the  past  three  weeks,  proved  the  value  of  the 
muriate  of  cocaine  as  a  local  anaesthetic,  in  strabismus  by 
six  operations,  in  congenital  and  cortical  cataract  by  four 
operations,  and  in  iridectomy  by  three  operation-,  besides 
several  minor  operations  on  the  cornea,  I  wish  to  lay 
before  the  readers  of  The  Medical  Record  two  points 
in  its  use  which  seem  to  render  it  more  efficient.  I  apply 
it  in  the  form  of  spray  with  a  hand  atomizer  and  get  a 
inoro  rapid  effect,  as  the  movements  of  the  lids  and  the 


lachrymal  secretion  do  not  carry  off  the  solution  as 
quickly  as  when  dropped  into  the  conjunctival  sac 

"In  my  first  case  of  iridectomy  with  cocaine,  while  the 
cornea  was  insensitive,  the  iris  was  unaffected  by  the 
external  application,  and  its  seizure  with  the  forceps  was, 
as  usual,  quite  painful.  In  two  cases  of  iridectomy, 
both  nervous  females,  five  minutes  after  spraying  the 
cornea  a«^d  conjunctiva,  I  made  the  corneal  incision  with- 
out pain,  then  injected^  by  means  of  a  small  lachrymal 
syringe^  two  (2)  drops  of  the  two  per  cent,  solution  inh 
the  anterior  chamber^  and  three  minutes  later  seized  the 
iris  with  the  forceps,  drew  it  out,  and  completed  the 
operation  without  causing  pain  to  the  patient. 

"  No  reaction  followed  its  intraocular  use  J* 


FAILURES  WITH  COCAINE. 

Dr.  F.  C.  Riley,  of  this  city,  makes  a  report  of  two 
cases  in  op'.ithalmic  practice  which  demonstrate  that  the 
much  lauded  new  remedy  is  not  always  as  reliable  as 
might  be  wished. 

Case  1. — Granular  lids  with  intense  pannus  occurring 
in  a  girl  of  ten  years.  The  photophobia  in  this  case  was 
so  marked  that,  upon  facing  the  patient  toward  the  win- 
dow in  an  ordinarily  well-lighted  room,  the  eyeball  rolled 
upward  and  inward  to  such  a  degree  as  to  completely  hide 
the  w^ole  corneal  expanse  from  vie w,  unless  the  superior 
palpebral  covering  was  lifted. 

Two  drops  of  a  two  per  cent,  solution  of  Merck's  co- 
caine was  instilled,  at  intervals  of  ten  minutes,  for  a  period 
of  half  an  hour,  or  three  instillations  in  all,  with  no  per* 
ceptible  effect  either  as  regarded  dinrinution  of  sensibility 
to  light  or  touch.  Neither  was  there  any  appreciable 
effect  produced  upon  the  size  of  the  pupil,  nor  did  the  drug 
affect  the  circulation  so  far  as  it  was  possible  to  observe  it. 

Three  days  subsequent  to  the  preceding  trial,  I  de- 
termined upon  operating  to  relieve  the  pannus,  and  again 
tried  the  same  solution,  instilling  four  drops  every  five 
minutes  for  a  period  of  three-quarters  of  an  hour,  or  in 
all  nine  instillations.  Careful  efforts  to  touch  the  con- 
junctiva or  cornea  at  any  part  thereof,  between  each  in- 
stillation, failed  to  elicit  the  slightest  evidence  of  anything 
even  approximating  a  condition  of  anaesthesia.  Feeling 
that  a  fair  trial  had  been  given  the  dnig  in  this  case,  I 
proceeded  to  the  use  of  ether  and  performed  syndectoniy. 

Case  II. — A  lad  about  twelve  years  of  age,  who  had  a 
perforating  ulcer  of  the  cornea  about  six  months  since, 
with  prolapsus  of  iris  into  the  perforation,  etc.  Cornea 
almost  completely  cloudy  or  pearly.  To  the  outer*  and 
upper  segment  yet  remained  a  small  spot  of  transparent 
tissue,  at  which  point  I  deemed  it  advisable  to  perfonn 
an  iridectomv  in  order  to  free  the  entrapped  iris,  which 
seemed  to  produce  a  constant  irritability  of  the  eye. 
Vision-perception  of  light  only.  Using  the  same  solution 
of  cocaine  as  in  the  former  case,  four  drops  every  ten 
minutes  for  forty  minutes,  with  absolutely  no  effect  of 
any  kind,  either  to  cornea  or  conjunctiva,  led  me  to  the 
opinion  that  the  solution  was  not  what  it  should  be. 
Subsequent  results  with  the  same  solution  have,  however, 
dispelled  my  suspicion  as  to  the  sample  used,  as  I  have 
since  obtained  all  the  physiological  effects  so  far  noted 
by  other  observers.  The  two  cases  recorded,  however, 
seem  to  me  to  prove  beyond  the  suspicion  of  a  doubt  that 
there  are  certain  conditions,  pathological  maybe,  or  in- 
dividual idiosyncracies,  possibly  both,  that  tend  to  mili- 
tate against  the  verdict  so  generally  expressed  thus  Car 
in  favor  of  the  anaesthetic  effects  of  the  drug.  It  seems 
to  me  that  in  the  use  of  this  substance,  the  cases  of  failure 
to  obtain  the  desired  end  should  be  placed  before  your 
readers  as  well  as  the  brilliant  results  obtained  by  so  many 
of  us.  That  it  has  been  a  great  blessing  to  many  during 
its  short  career  there  is  no  doubt,  and  that  it  will  con- 
tinue  to  prevent  the  attendant  pain  of  many  operations 
in  the  future  I  am  confident.  Even  if  it  gives  as  universal 
satisfaction  in  time  to  come  as  it  has  in  my  hands  thus 
far,  it  is  indeed  a  friend  to  the  suffering  and  distressed. 


December  13,  1884.] 


THE   MEDICAL  RECORD. 


659 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


6EORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co..  Nos.  56  and  58  Ufayette  Place. 

New  York|  December  is,  2884. 

THE  EARLIER  EMPLOYMENT  OF  COCAINE. 

While  the  enthusiasm  for  cocaine  continues  but  slightly 
abated  in  its  intensity,  a  brief  reference  to  some  of  the 
results  recently  obtained,  as  compared  with  the  earlier 
records  of  its  employment,  r^iay  prove  interesting. 

In  1859  Mantegazza  ("Sulle  virtCl  igieniche  e  medici- 
nal! della  Coca,'*  pp.  76,  Milano)  noted  the  soothing 
influence  exercised  by  the  leaves  of  erythroxylon  coca, 
when  broOght  in  contact  with  mucous  membranes.  Lit- 
erature^ however,  seems  almost  unanimous  in  conceding 
to  Niemann  (i860)  the  credit  of  being  among  the  first 
to  isolate  cocaine  and  give  it  a  certain  amount  of  phys- 
iological individuality. 

This  investigator  is  mentioned  as  having  observed  sev- 
eral of  the  now  recognized  properties  of  cocaine ;  but, 
singular  to  relate,  he  stated  it  possessed  no  action  upon 
the  eye.  The  postponement  of  the  discovery  of  its  an- 
aesthetic action  upon  the  eye  was  probably  owing  to  this 
misleading  remark.  Its  employment  in  the  throat,  sub- 
sequent to  Niemann's  observation  of  its  action  upon  the 
tongue,  furnishes  some  grounds  for  such  an  inference.  In 
1877  Ch.  Fauvel,  of  Paris  [Gazette  des  Ildpitaux,  \>2ig<t 
427),  is  reported  by  Dr.  Scaglia  as  having  utilized  the  an- 
aesthetic property  of  cocaine  to  afford  relief  in  painful 
anginae.  Jelinek  (Wiener  Medizinische  Wochenschrift^ 
No.  46,  1884)  claims  to  have  successfully  employed  co- 
caine to  relieve  painful  deglutition  in  ulcerative  laryn- 
geal phthisis. 

Equally  interesting  are  the  experiments  of  Thomas 
Moreno  y  MaTz  (1868),  detailed  in  his  monograph  **Re- 
cherches  cliniques  et  physiologiques  sur  FErythroxylum 
Coca  et  la  Cocaine,"  pp.  90.  The  acetate  of  cocaine 
was  employed  in  his  experiments.  Particularly  interest- 
ing are  his  observations  upon  the  hypodermic  employ- 
ment of  cocaine.  He  injected  a  solution  of  the  acetate 
of  cocaine  into  the  leg  of  a  frog,  and  observed  after  the 
expiration  of  ten  minutes  distinct  loss  of  superficial  sen- 
sibility over  a  circumscribed  area ;  the  most  powerful 
irritants  failed  to  provoke  motion.  In  a  quarter  of  an 
hour  the  sciatic  nerve  was  laid  bare,  and  sensation  was 
observed  to  be  completely  abolished.  The  conclusion 
he  arrived  at,  "  Pourrait-on  Temployer  (cocaine)  comme 
anesth6sique  local,'*  though  slowly  accepted,  has  been 
remarkably  well  verified. 

The  employment  of  the  hypodermic  method  for  the 
painless  removal  of  tumors  has  been  recently  followed  by 
excellent  results  in  hospital  practice.    A  body  of  gentle- 


men, in  this  city,  composed  of  willing  medical  students 
and  intelligent  surgeons,  have  been  experimenting  with, 
a  view  to  determine  the  hypodermic  effects  of  co- 
caine when  applied  directly  to  the  sensory  cutaneous, 
nerves.  In  twenty  minutes  after  the  introducticwi  of  fif- 
teen minims  of  a  four  per  cent,  solution,  all  the  parts  sup- 
plied by  the  anaesthetized  nerve  were  rendered  analgesic 
The  constitutional  effects  (vertigo,  nausea,  etc.)^  were- 
mild  and  transient  in  character.  If  the  infierences  de- 
divced  from  these  observations  are  correct,  this  property 
of  cocaine  to  affect  all  the  nerve-terminak  whea  applied 
to  a  particular  radical  must  prove  of  great  service  for  the 
performance  of  many  major  as  well  as  minor  surgical  op- 
erations. 

In  1880  Von  Aurep  ("Archives  fiir  Physiologie") 
elaborated  a  series  of  experiments  with  cocaine,  care- 
fully conducted  upon  warm-  and  cold-blooded  animals 
and  upon  himself.  Prominent  among  the  results  re- 
corded is  its  action  on  the  pupil. 

The  value  of  cocaine  for  the  relief  of  pain  in  many- 
acute  and  chronic  affections  is  no»w  well  recognized.  I* 
has  been  employed  for  this  purpose  in  diseases  of  the- 
eye,  ear,  throat,  urethra,  etc.  Inj.ected  into  the  urethra  it 
has  converted  internal  urethrotomy  into  a  painless  pro- 
cedure. The  combined  employment  of  cocaine  and 
rhigolene  in  operations  on  the  nose  is  recorded  in  the 
present  issue  of  this  journal. 

On  account  of  the  high  price  of  the  imported  article 
an  attempt  has  been  made  to  produce  a  domestic  prep- 
aration of  the  salt.  Aside  from  those  preparations, 
claimed  as  proprietary,  but  really  consisting  of  an  im- 
ported alkaloid  combined  with  a  domestic  acid,  a  large 
proportion  of  the  home-made  cocaine  has  proved  unre- 
liable. 

DEAD  TEETH  IN  THE  JAWS. 

We  are  in  receipt  of  numerous  communications  on  the- 
above  subject,  mostly  covering  ground  that  has  already 
been  gone  over,  and  we  have  not  space  to  give  the  mat- 
ter further  attention  at  this  time  than  to  allude  to  some 
points  in  a  letter  on  this  subject  from  Dr*  G.  V.  Black,  ai 
dentist  of  Jacksonville,  111.,  who  regards  this  as  **  simply 
a  question  in  pathology,"  and  objects  to  the  term  "  dead, 
teeth,"  since  dentists  hold  that  in  death  or  intentional  de- 
struction of  the  pulp  the  dentine  only  loses  its  vitality; 
and  that  while  •*  the  tooth  is  retained  in  heahhy  connec- 
tion with  the  alveolar  process,"  the  cementum  and  peri- 
osteal membrane  remain  "  unaffected "  so  far  as  the 
death  of  the  pulp  is  concerned.  We  can  but  regard  this, 
assertion  as  much  too  sweeping,  since  when  the  greater 
part  of  the  tooth  is  in  a  pathological  condition  it  cannot 
ever  afterward  be  considered  as  sound  unless  it  were- 
known  that  a  reparative  process  began  after  so  great  an. 
injury  rather  than  one  of  a  destructive  character.  The 
progress  of  disease  in  these  parts  is  pretty  well  under-^ 
stood  ;  it  consists,  first,  in  disturbances  in  the  cementum^ 
which  immediately  overlies  and  is  continuous  with  the 
lifeless  dentine  of  pulpless  teeth  ;  and,  second,  in  the  in-- 
flammation  of  the  periosteal  covering  of  the  cementum.. 
The  acute,  subacute,  or  chronic  pericementitis  thus  estab- 
lished extends  itself  very  often  until  the  nutrition  of  the- 
cementum  is  seriously  interfered  with  and  destructive  in- 
flammation of  portions  of  the  cementum  follows.     This 


66o 


THE   MEDICAL  RECORD. 


[December  13, 1884, 


is  finally  attended  by  contaminating  secretions  which  may 
be  absorbed  after  entering  the  tissues,  or  swallowed. 
But  even  more  danger  to  the  patient  may  arise  fromjthe 
nervous  irritation  propagated  by  these  diseased  teeth^; 
important  regions  are  often  thus  affected.  Morbific  in- 
fluences of  this  kind  may  continue  on  almost  indefinitely 
without  perceptible  disturbance  in  the  tooth,  and  being 
thus  unsuspected,  health  may  be  undcrmined^before  the 
cause  is  discovered.  To  advise  that  such  teeth  are 
harmless  because  the  local  irritation  is  scarcely  percegti- 
ble  is,  in  many  cases,  to  bring  about  irreparableXinjury 
to  health.  While  instances  of  harm  from^retention'of 
such  defective  teeth  are  so  frequently  occurring  in  prac- 
tice, and  persons  with  dental  skill  are  unable  to  realize 
the  mischief  being  done,  the  safer  course  is  to  advise  that 
all  dead  teeth  be  removed,  at  least  until  such  time  ar- 
rives  when  medical  specialists  can  determine  with  cer- 
tainty that  teeth  are  not  the  seat  of  any  trouble  that  can 
possibly  injure  the  patient. 


THE    REPORT    OF    THE     SURGEON-GENERAL   OF    THE 
UNITED  STATES  ARMY. 

The  annual  report  of  the  Surgeon-General  of  the  Army 
for  1884  has  been  received,  and,  like  previous  reports, 
touches  upon  subjects  of  general  interest.  Our  army 
now  consists  of  20,230  white,  2,309  colored  troops,  and 
210  Indian  scouts.  Among  the  white  troops  there  were 
on  the  average  1,003,  or  5°  per  1,000,  constantly  sick, 
being  a  slight  increase  over  the  previous  year.  Of  the 
sick,  eighty  per  cent,  were  under  treatment  for  disease, 
and  twenty  per  cent,  for  wounds,  accidents,  and  injuries. 
The  total  number  of  deaths  was  250,  or  12  per  1,000,  a 
slight  increase  over  last  year,  despite  the  fact_[that  we 
had  no  Indian  fights  during  1883-84. 

It  is  interesting  to  note  that  for  the  first  time  on  record 
the  mortality  of  the  colored  soldiers  was  less  than  that  of 
the  white,  it  being  only  10  per  1,000.  The  ratio  of 
sickness  was  very  slightly  greater  among  the  colored 
troops.  These  latter  suffered  more  from  venereal  dis- 
eases and  less  from  intemperance  than  the  white  troops. 
From  which  it  may  be  provisionally  inferred  that  while 
the  white  man  takes  to  wine,  the  black  man  prefers  the 
woman. 

Comparative  statistics  show  that  the  white  troops  are 
more  susceptible  to  malarial  disease  than  the  black,  the 
difference  being  about  76  per  1,000  of  mean  strength  in 
favor  of  the  negro. 

It  is  further  stated  that  typhoid  fever  attacks  the  whites 
one-third  oftener  than  the  negroes,  but  that  the  mortality- 
rate  from  this  disease  is  twice  as  great  in  the  latter  as  in 
the  former. 

Typhoid  fever  prevailed  among  the  troops  more  ex- 
tensively than  it  has  done  since  the  war.  It  is  gratifying 
to  note,  however,  that  the  mortality  from  this  disease 
among  the  white  troops  has  fallen  from  twenty-one  per 
cent,  to  sixteen  per  cent. 

Regarding  the  Army  Medical  Museum,  the  Surgeon- 
General  states  that  during  the  year  there  have  been  144 
accessions,  making  a  total,  June  30,  1884,  of  9, 1 14  speci- 
mens. 

As  to  the  Library,  we  learn  that  the  additions  during 
the  past  year  include  about  4,000  volumes  and  5,500 


pamphlets.  By  actual  count  at  the  end  of  the  fiscal  year 
the  Library  contained  65,738  volumes  and  86,503  pam- 
phlets. 

The  need  of  a  new*fire-proof  building  is  again  insisted 
upon. 

The  publication  of  the  third  and  last  medical  volume 
of  the  "  Medical  and  Surgical  History  of  the  War"  was       1 
delayed  by  the  untimely  death  of  Dr.  Woodward.    The 
completion  of  this  volume,  however,  has  been  placed  in       ' 
the  hands  of  Surgeon  Charles  Smart,  and  it  will  probably       | 
appear  soon. 

One  year  ago  there  were  fourteen  vacancies  in  tbe 
grade  of  Assistant  Surgeon ;  since  then  five  officers 
have  died  or  resigned.  Daring  the  year,  however,  twenty- 
two  candidates  have  been  found  qualified,  and  there  are 
now  no  vacancies  in  the  medical  corps  of  the  army. 


THE    LAST    REPORT  OF    THE  NATIONAL    BOARD  OF 
HEALTH. 

The  "  Annual  Report  of  the  National  Board  of  Health  for 
1883"  reaches  us  somewhat  over  a  year  after  its  first 
presentation  to  Congress.  The  contents  of  the  report 
itself  in  consequence  are  already  in  large  measure  known. 

The  more  active  work  of  the  Board  as  regards  quaran- 
tine and  scientific  investigation  was  suspended  by  action 
of  law  in  June,  1883,  consequently  occasion  is  taken  in 
the  present  report  to  review  the  history  of  the  four  yean 
of  the  Board's  existence. 

We  learn  that  in  that  time  there  were  appropriated  for 
its  use  $767,500,  of  which  $639,446.19  were  expended 
The  largest  sums  were  employed  ill  sustaining  a  floating 
quarantine  on  the  Mississippi.  About  $36,000  was  given 
to  aid  the  State  Board  of  Health  of  Tennessee,  while 
sums  of  from  three  to  eleven  thousand  dollars  were  given 
to  help  other  localities.  About  $35,000  was  spent  in 
special  scientific  investigations. 

The  sum  appropriated  for  the  Board  in  1882  was  but 
$50,000,  while  in  1883  the  annual  appropriation  was  cut 
down  to  $10,000. 

The  work  of  the  Board  has  consisted  mainly  in  assist- 
ing, by  advice  and  money,  local  health  authorities,  in 
establishing  maritimel  quarantine  stations,  in  inaugurating 
an  interstate  and  immigrant  inspection  service,  in  secur- 
ing the  co-operation  of  the  United  States  consuls,  and  in 
prosecuting  certain  scientific  investigations.  Owing  to 
the  lack  of  funds,  the  immigrant  inspection  service  has 
now  been  discontinued,  the  Mississippi  Valley  inspection 
service  has  been  transferred  to  the  Sanitary  Council  of 
the  Mississippi  Valley,  the  maritime  quarantine  stations 
have  passed  to  the  care  of  the  Marine  Hospital  service, 
while  the  scientific  work  has  been  entirely  abandoned. 

The  Board  requests  that  the  powers  originally  con- 
ferred upon  it  be  restored ;  meanwhile  it  asks  that  the 
sum  of  $37,700  be  appropriated  for  actual  expenses  and 
to  enable  it  to  perform  the  duties  required  of  it  by  the 
second  section  of  the  Act  of  March  3,  1879. 

Appended  to  the  report  are  several  scientific  com- 
munications and  special  reports.  The  articles  on  "Beri- 
beri in  Ceylon,"  on  "Leprosy  in  Maracaibo,"  on  "The 
Filaria  Disease,"  and  the  reports  on  cholera  in  Japan 
and  in  China,  are  of  especial  interest 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


661 


SOME  FACTS  ABOUT  ADULTERATED  DRUGS. 
Pr.  Bennett  F.  Davenport,  Food  Inspector  of  Massa- 
chusetts, makes  a  brief  report  in  The  Sanitarian  of  some 
of  the  results  which  he  has  obtained  in  examining  for 
adulterations  in  drugs  under  the  excellent  law  of  his 
State. 

Under  this  act  the  last  version  of  the  United  States 
Pharmacopoeia  is  made  the  standard. 

Dr.  Davenport  during  his  first  year  examined  about 
three  hundred  sample^  of  pharraacopoeial  drugs,  and 
found  that  about  forty  per  cent,  did  not  conform  to  the 
requirements.  Among  the  drugs  examined  were  one 
hundred  samples  of  tincture  of  opium.  Of  these  four 
only  exceeded  the  maximum  allowable  strength  of  1.60 
per  cent,  morphine  according  to  the  1880  Revision  of 
the  United  Stales  Pharmacopoeia ;  while  eighty-two  fell 
below  the  minimum  allowed  of  1.20  per  cent.,  forty- 
dirce  only  fell  below  the  about  0.90  per  cent,  morphine 
which,  according  to  the  Revision  of  1880,  was  the  quan- 
tity required  by  the  Revision  of  1870.  Their  average 
strength  was  0.965  per  cent,  morphine,  the  extreme 
being  0.336  and  1.87  per  cent. 

It  is  thus  shown  that  some  samples  of  laudanum  are 
nearly  six  times  stronger  than  others.  Dr.  Davenport 
also  concludes  that  there  is  much  greater  apparent  than 
real  change  in  the  strength  of  laudanum  made  according 
to  the  1880  Revision  of  the  United  States  Pharmacopoeia. 

Of  the  simple  cinchona  alkaloid  salts  about  twenty-five 
per  cent,  were  found  to  contain  an  excess  of  the  cheaper 
alkaloids. 

About  two  hundred  samples  of  powdered  pharmaco- 
poeial  drugs  were  examined  microscopically,  and  about 
twenty  per  cent,  were  found  to  contain  foreign  ingredi- 
ent, or  rather  appeared  so,  for  it  is  not  common  now 
as  formerly  that  totally  foreign  substances  are  introduced, 
but  it  is  the  closely  allied  and  inferior  varieties,  or 
damaged  samples  and  trimmings  of  the  very  same 
drug,  that  are  used.  Millers  now,  says  Dr.  Davenport, 
study  structural  botany,  and  are  becoming  as  expert  as 
those  whose  duty  it  is  to  expose  their  improper  practices. 

The  excellent  suggestion  is  made  that  there  be  organ- 
ized in  this  country  a  Society  of  Public  Analysts  similar 
to  that  which  has  done  so  much  good  work  in  England. 

The  results,  on  the  whole,  of  Dr.  Davenport's  exami- 
nations are  not  calculated  to  excite  alarm.  They  show 
that  druggists  are  slow  in  adopting  the  changes  of  the 
last  Pharmacopoeia,  and  that  manufacturing  pharmacists 
are  inclined  to  make  their  preparations  a  little  weaker 
than  the  standard,     

i         THE   CLINICAL  DEPARTMENT  OF  THE  RECORD. 

i  The  very  large  number  of  short  clinical  communications 
sent  to  us  by  our  readers  in  all  parts  of  the  country  has 
been  a  source  both  of  gratification  and  perplexity.  While 
conscious  of  their  practical  value  it  has  often  been  im>- 
possible  to  give  them  either  the  space  or  the  prominence 
they  deserve.  We  have  resolved,  therefore,  to  remedy  the 
matter  in  a  measure  by  establishing  a  Clinical  Depart- 
ment in  which  the  choicest  and  most  original  articles  re- 
ceived will  be  placed,  and  published  in  such  a  way  as  to 
call  to  thena  proper  attention.  The  present  issue  of  The 
Record  contains  the  first  instalment  of  these  clinical 
notes,  and  we  feel  sure  that  now  and  hereafter  they  will 


form  a  most  attractive  and  instructive  feature  in  our 
pages.  It  is  hardly  necessary  to  say  to  our  contributors 
that  communications  for  this  department  should  be  brief, 
practical,  and  to  the  point,  and  should  express  some  ac- 
tual lesson  taught  by  the  Writer's  own  experience.  For 
the  rest,  clinical  notes  may  cover  the  whole  range  of 
practical  medicine,  surgery,  obstetrics,  and  therapeutics* 


THE  ABUSE  OF  SUBSCRIPTION  CLUBS. 

It  may  be  charged  that  we  are  writing  with  a  bias^ 
nevertheless  we  cannot  refrain  from  making  a  little 
protest  against  the  abuse  of  subscription  clubs.  It  is  a 
very  widespread  practice  among  the  physicians  of  towns 
and  cities  to  club  together  and  take  a  number  of  medical 
journals.  This  is  a  wise  and  economical  plan,  up  to  a 
certain  extent ;  but  every  physician  ought  to  have  one 
or  two  journals  as  his  own  personal  property,  and  the 
subscription  club  not  infrequently  prevents  this.  It  is 
not  the  hasty  week-to-week  reading  of  numerous  medical 
journals  which  is  helpful  to  a  doctor.  He  must  have  the 
volumes  on  his  shelf  to  refer  to  in  studying  his  cases  or 
preparing  his  papers.  It  is  an  essential  now  in  medical* 
writing  that  the  author  know  what  has  been  said  already 
on  his  subject.  Still  more  important  to  the  practitioner 
is  it  that  he  prescribe  no  therapeutical  measure  that  has 
already  been  shown  to  be  useless,  and  that  he  leave  his 
patient  with  no  remedy  untried.  To  a  practitioner  the 
bound  volumes  of  his  standard  medical  journal  are  more 
valuable  than  text-books.  We  speak  what  is  only  the 
ordinary  teaching  of  good  sense,  therefore,  when  we  say* 
that  it  is  neither  wise  nor  economical  for  a  doctor  to 
depend  alone  upon  a  weekly  visitation  of  a  few  journals 
for  his  scientific  culture,  or  to  keep  him  really  abreast  <rf 
the  medical  progress  of  the  day. 


FURTHER  DISCOVERIES  IN  CHOLERA,  AND  CONFIRMA^ 
TIONS  OF  KOCH'S  VIEWS. 

We  learn  that  Dr.  Rudolph  Emmerich,  of  Munich,  who 
has  been  studying  the  cholera  in  Naples,  has  discovered 
a  peculiar  micro-organism  in  the  blood  and  tissues  of 
persons  affected  with  that  disease.  This  organism  already 
goes  by  the  name  of  the  ''  Emmerich  Bacillus."  It  wa& 
found  in  the  internal  organs  and  blood  in  nine  autopsies, 
and  in  the  blood  from  the  arm  of  one  living  cholera  pa- 
tient. 

Dr.  E.  Van  Ermengen  has  communicated  to  the  Mi* 
croscopical  Society  of  Belgium  the  results  of  his  patho- 
logical studies  of  cholera.  He  has  made  eight  autopsies 
and  thirty-four  examinations  of  stools.  The  comma* 
bacilli  have  been  cultivated,  and  successfully  inoculated 
in  dogs,  rabbits,  and  guinea-pigs.  His  conclusions  are 
almost  identical  with  those  of  Koch.     He  says  : 

**The  pathogenic  action  of  these  products  of  cultiva^ 
tion  is  very  likely  due  to  a  zymosis,  to  an  unstable  albu- 
minoid compound.  Corpuscles  of  fresh  human  blood 
placed  on  Ranvier's  heated  platinum,  and  brought  into 
contact  with  a  drop  of  a  serum-culture,  present  charac- 
teristic changes  wholly  comparable  with  those  described 
by  MM.  Nicati  and  Rietsch  in  their  observations  on  the 
blood  of  chpleraic  cases. 

'*  The  discovery  of  the  comma-bacillus  is  of  the  great- 
est importance  in  the  diagnosis  of  choleriform  attacks  of 


662 


THE  MEDICAL  RECORD. 


[December  13, 


doubtful  nature  which  occur  at  the  commencement  of 
epidemics,  and  for  the  resort  to  more  effective  prophy- 
lactic measures  which  this  early  diagnosis  allows. 
-  "  The  employment  of  bacterioscopic  methods  in  the 
/diagnosis  of  cholera  does  not  offer  any  great  difficulty  in 
)  practice,  and  it  would  be  very  desirable,  in  view  of  the 
serious  threats  of  an  invasion  of  Belgium  by  cholera, 
that  a  sufficient  number  of  physicians  employed  in  the 
sanitary  services  should  be  initiated  therein  with  the  least 
possible  delay." 

.^  ,  ■■ .,  — ■ 

Ninth  International  Congress. — The   committee 
^n  organization  has  elected  the  following  officers  :  Presi- 
jdeni-^Dr,  Austin  Flint,  Sr.,  New  York  ;    Vice-Presidents 
— Drs.  Alfred  Stills,  Philadelphia;  Henry  I.  Bowditch, 
Boston  ;  R.  P.  Howard,  Montreal ;  Secretary- General — 
Dr.   J.   S.  Billings,  U.S.  Army;  Treasurer— Vix.].   M. 
Brown,  U.  S.  Navy ;  Members  of  Executive  Committee 
.y(in  addition  to  President,  Secretary-General,  and  Treas- 
urer)— Dr.  I.  Minis  Hays,  Philadelphia;  Dr.  A.  Jacobi, 
New  York  ;  Dr.  Christopher  Johnston,  Baltimore  ;  and 
Dr.  C.  Busey,  Washington.     The  meeting  is  to  be  held  in 
Washington,  D.  C,  in  1887.     The  membership  will  be 
.composed  of  delegates  from  each  of  the  regularly  organ- 
ized general,  State,  and  local  medical  societies.     The  of- 
ficial languages  will  be  English,   French,   and  German. 
"The  published  discussions  will  be  in  English;  and  the  pa- 
.pers  in  the  languages  in  which  they  are  delivered.     The 
work  of  the  Congress  will  be  divided  into  eighteen  sec- 
tions.    The  detail  of  organization  is  to  be  entrusted  to 
tthe  Executive  Committee. 

Dr.  Livingston  S.  H  inkle v,  of  New|York  City,' has 
.been  appointed  Medical  Superintendent  of  the  Essex 
"County  Asylum  for  the  Insane,  Newark,  N.  J. 

In  Case  of  Cholera. — The  Board  of  Estimates  and 
Apportionment  of  this  city  has  added  $50,000  to  the 
estimate  for  the  Health  Department,  to  be  used  in  case 
of  cholera.  This  is  very  well,  but  an  additional  sum 
.ought  to  be  given  at  once  for  the  purpose  of  preventing 
the  cholera's  entrance. 

Politics  and  Sanitation. — There  can  be  little  doubt 
.that  the  New  York  City  Health  Board  is  seriously  crip- 
.^led  by  bad  x^olitical  influences.  It  is  an  open  secret 
now  that  the  Board  has  not  suppressed  the  manure 
.dump  nuisances  because  the  owners  of  them  were  of  too 
great  political  importance.  The  slums  and  unhealthful 
tenements  of  the  city  cannot  be  cleaned  or  improved  in 
many  cases  because  their  owners  possess  too  much 
4)ower  in  the  wards.  The  President  of  the  Board  of 
Health  was  ajjpointed  as  the  result  of  a  "deal"  be- 
tween Tammany  Hall  and  the  Republican  machine. 

Caution  in  the  use  of  Cocaine. — Since  the  paper 
of  Dr.  Knapp^vide  page  656)  was  in  type  we  have  re- 
.ceived  the  following  note  from  that  gentleman  :  "  Will 
you  allow  me  to  add  a  word  of  caution  to  the  communi- 
.  cation  on  *  Cocaine'  which  I  sent  you  a  week  ago.  I 
.injected  6  minims  of  a  four  per  cent,  solution  into  the 
.orbit,  close  to  the  posterior  segment  of  the  eyeball. 
'The  anaesthesia  in  Ikatipart  was  complete,  and  the  oper- 


ation and  recovery  of  the  patient  were  without  any  dis- 
turbance.    During  the  operation  I  noticed  that  the  pa- 
tient's  face  became  quite  pale.     I  omitted  to  mention 
this  in  my  communication,  as  the  patient  did  not  com- 
plain.    To-day,  likewise,  at  the  University  College  CH- 
nic,  I   injected   5  minims  of  a  three  per  cent,  solution 
underneath  a  sebaceous  tumor,  the  size  of  a  small  wal- 
nut, situated  in  the  centre  of  the  upper  lid.    The  anaes- 
thesia was  almost  complete,  and  the  somewhat  laborious 
operation  passed  satisfactorily,  but  during  it  the  patient 
became  as  pale  as  a  corpse,  felt '  somewhat  faint,  asked 
repeatedly  for  drink,  and  was  covered  with  cold  perspi- 
ration.    In  about  fifteen  minutes  this  condition  of  dis- 
tress, which  was,  however,  in  no  way  alarming,  dvsap. 
peared.     Though  much    larger  doses — Hepburn,  HaB, 
etc. — have  been  hypodermically  injected  before  gencnd 
symptoms    manifested    themselves,  I  think  that  five  or 
six  minims  of  a  three  per  cent,  solution  may  be  too 
much  for  the  orbit.     The  orbital  cellular  tissue  is  so  vas- 
cular that  it  resembles  cavernous  tissue.      Liquids  in- 
jected into  it  may  enter  the  general  circulation  more 
readily  than   from   other  parts.     In   further  operations 
I  shall  inject  no  more  than  one  or  two  minims,  and  grad- 
ually feel  my  way.    I  beg  you,  dear  doctor,  to  grant  this 
note  a  place  in  your  columns,  for  I  would  deeply  regret 
if  my  previous  communication  should  be  the  cause  of  an 
unpleasant  accident  by  inducing  somebody  to  inject  too 
large  a  dose  of  cocaine  into  the  orbit." 

New  York  Academy  of  Medicine. — At  the  stated 
meeting  held  December  4,  1884,  the  following  nomina- 
tions were  made  for  officers.  For  President:  Drs. 
Samuel  T.  Hubbard,  A.  Jacobi,  William  T.  Lusk,  T. 
Gaillard  Thomas,  and  C.  R.  Agnew.  For  Vice^PresUtid: 
Drs.  C.  C.  I*ee  and  T.  Addis  Emmet.  For  Correspond- 
ing  Secretary:  Drs.  Paul  F.  Mund^,  H.  Knapp,  and  L 
Elsberg.  For  Trustee  :  Drs.  H.  T.  Hanks,  A.  L.  Loomis, 
J.  Williston  Wright,  E.  Eliot,  and  Frank  H.  Hamilton. 
For  Member  of  Committee  on  Admissions  :  Drs.  William 
M.  McLaury,  Seneca  D,  Powell,  A.  S,  Hunter,  C.  A. 
Leale,  L.  Elsberg,  and  J.  A.  Wyeth,  For  Member  of 
Committee  on  Medical  Education  :  Drs.  Joseph  D.  Bryant, 
F.  R.  Sturgis,  and  Stephen  Smith.  For  Member  of  Com- 
mittee on  Ethics :  Drs.  A.  Hadden,  A.  S.  Hunter,  T.  G. 
Thomas,  T.  E.  Salter thwaite,  and  Andrew  H.  Smith. 
For  Member  of  Committee  on  Library  :  Drs.  E.  Darwin 
Hudson,  Jr.,  and  George  M.  Lefferts. 

Cocaine  Ointment  for  Piles. — Dr.  F.  A.  Bunall 
writes  :  "  Please  mention  in  your  coca  literature  that  the 
coca  leaves  treated  with  heated  lard  and  an  alkali,  form 
an  ointment  resembling  stramonium  ointment,  which 
seems  to  possess  soothing  properties.  Applied  to  the 
tongue  it  leaves  an  impression  similar  to  that  produced 
by  a  solution  of  muriate  of  cocaine.  This  ointment,  pre- 
pared at  my  request  by  a  leading  pharmacist  of  this 
city,  has  been  used  in  three  cases  of  hemorrhoids  with 
the  effect  of  alleviating  pain.  The  muriate  of  cocaine 
will,  I  think,  be  found  of  service  in  such  cases,  and 
this  alkaline  ointment  is  also  worthy  of  further  trial  as  a 
local  anodyne." 

Dr.  W.  B.  De  Garmo  has  been  appointed  Assistant 
to  the  Chair  of  Orthopaedic  Surgery  in  the  New  York 
Polyclinic. 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


663 


Dr.  R.  VV.  Wilcox  has  been  appointed  one  of  the  As- 
sistants to  the  Chair  of  Neurology  at  the  New  York  Post- 
graduate Medical  School. 

The  Discoverer  of  the  An/esthetic  Powers  of 
Cocaine. — Dr.  W.  Oliver  Moore  writes  that,  in  a  letter 
received  last  week  from  Dr.  Koller,  it  appears  that  he  ' 
not  only  first  used  it  on  the  eye,  but  suggested  its  use  on 
the  throat  to  his  laryngological  friends  in  Vienna,  instead 
of  getting  his  idea /r(7/»  them^  as  has  been  inaccurately 
reported  in  many  of  the  journals.  Dr.  Koller  is  second 
physician  to  the  Vienna  General  Hospital. 

Insane  Asylum  Reform. — Much  disturbance  has 
been  excited  in  the  Cook  County  Insane  Asylum  re- 
cently over  the  revelations  in  the  past  management  of 
the  institution  recently  brought  out.  The  asylum,  al- 
though built  for  only  300  patients,  has  been  made  to 
hold  558.  It  has  been  managed  by  local  politicians, 
and  the  officers  and  attendants  have  been  more  skilled 
in  politics  than  in  the  care  of  the  sick.  Dr.  Clevinger, 
special  pathologist,  recently  made  specific  charges  against 
the  warden,  matron,  and  other  employees.  An  investi- 
gation has  followed.  We  learn,  however,  that  the  Com- 
missioners, after  a  recent  visit,  decided  that  everything 
was  in  good  condition,  and  ended  their  reformatory  toil 
with  a  champagne  supper.  The  trouble  excites  renewed 
interest  i  n  the  subject  of  the  prostitution  of  medical  char- 
ities to  p^olitics.  We  call  to  it  the  attention  of  that  use- 
ful but  polynomial  organization,  the  National  Associa- 
tion for  the  Protection  of  the  Insane  and  the  Prevention 
of  Insanity. 

Insusceptibility  to  Vaccination. — English  statistics 
show  that  about  one  infant  in  every  thousand  is  insus- 
ceptible to  vaccination. 

Tracheotomy  Aspirators. — One  result  of  the  sad 
death  of  Dr.  Rabbette  has  been  the  invention  of  several 
forms  oi  apparatus  for  sucking  secretions  from  the  trache- 
al wound.  One  of  the  simplest  of  these  is  made  on  the 
principle  of  a  drjj-cup  with  a  rubber  ball. 

'Proffered  Contribution  to  the  Edinburgh  Med- 
ical School. — Mr.  William  McEwan  has  offered  to  give 
$25,000  to  the  Edinburgh  Medical  School,  provided 
$50,000  is  raised  from  other  sources.  The  sum  of 
$75,000  is  needed  to  complete  and  furnish  the  building. 

Charges  against  Russian  Hospitals. — At  a  recent 
meeting  of  the  St.  Petersburg  Health  Committee,  some 
statements  were  made  which  throw  a  sinister  light  on 
some  of  the  Russian  hospitals  and  nurses.  Professor 
Botkin,  speaking  of  the  large  death-rate  in  the  St.  Peters- 
burg hospitals,  said:  '*I  have  come  to  the  conclusion 
that  the  patients  die  mostly  from  weakness,  for,  with  their 
daily  allowance  of  thirteen  or  fourteen  copecks,  they  can- 
not even  buy  a  pound  of  beef  for  broth.  In  addition  to 
this,  the  nurses,  who  are  very  badly  paid,  steal  the  food 
of  the  patients  whenever  they  can.' '  Considerable  sur- 
prise is  also  sometimes  expressed  in  St.  Petersburg  society 
at  the  rapid  growth  of  wealth  among  hospital  authorities. 

The  Ingestion  of  Cholera  Bacilli  and  Cholera 
Dejecta. — While  Dr.  Klein  has  swallowed  cholera  ba- 
cilli in  pure  cultures.  Dr.  Bochefontaine,  chief  of  Vul pianos 
laboratory y  has  swallowed  pills  composed  of  a  drachm 
of  diarrhceic  fluid  from  a  cholera  patient.     Dr.  B.  was  a 


little  ill  the  next  day,  but  had  no  choleraic  symptoms 
whatever.  We  observe  that  attempts  are  made  to  dis- 
credit the  value  of  the  above  experiments.  This  is  unjust, 
however.  If  Dr.  Klein  swallowed  the  true  bacilli  without 
harm,  while  in  a  cholera  country,  he  added  to  the  cholera 
question  some  negative  evidence  at  any  rate.  Dr.  Boche- 
fontaine's  experiment  tends  to  show  also  that  some  pecul- 
iar individual  factor  is  necessary  for  the  development  of 
the  disease. 

Death  of  M.  Fauvel. — The  death  of  M.  Fauvel,  the 
celebrated  French  sanitarian,  is  announced. 

Then  and  Now. — Fifty  years  ago  there  were  hardly 
any  such  things  as  dispensaries  or  out-patient  depart- 
ments. Now  in  every  large  city  a  fourth  of  the  inhabi- 
tants (if  we  go  by  reports)  are  annually  treated  for  noth- 
ing. The  effect  has  been  to  make  the  early  attainment 
of  professional  skill  more  easy,  but  the  early  attainment 
of  paying  professional  practice  more  difficult. 

The  most  Powerful  Antiseptics. — Studied  by  their 
power  to  prevent  the  development  of  micro-organisms  in 
sterilized  broth,  the  biniodid  of  mercury  stands  at  the 
head  of  the  list  of  antiseptics.  It  is  three  times  as  strong 
as  the  bichloride.  A  solution  of  a  ttj^ttd'  strength  ren- 
ders life  impossible  to  any  form  of  microbe,  says  M. 
Miguel,  while  of  bichloride  the  strength  must  be  y^^^* 
Iodide  of  silver  is  also  more  powerful  than  the  bichloride 
of  mercury. 

Board  of  Medical  Examiners  of  the  State  of  Vir- 
ginia.— ^The  Governor  of  Virginia,  William  E.  Cameron, 
has  approved  of  each  of  the  nominations  of  the  Medical 
Society  of  Virginia  made  during  its  last  session.  Of  the 
thirty-two  members,  only  one  is  "not  regular." 

Subcutaneous  Vaccination. — Bourgeois,  in  the  Bul- 
letin g^nhral  de  Thtrapeutique^  recommends  the  sub- 
cutaneous injection  of  vaccine  lymph  in  place  of  the 
endermic  method.  He  has  employed  the  new  method 
with  success. 

A  Bust  of  Dr.  J.  Marion  Sims. — A  bronze  bust  of 
Dr.  J.  Marion  Sims  by  Dubois,  of  Paris,  has  been  placed 
in  the  rooms  of  the  Medical  Library  Association  in  Bos« 
ton.  It  is  the  gift  of  a  lady  who  was  successfully  treated 
by  Dr.  Sims. 

The  Rugby  Game  op  Foot-ball. — The  decision  of  the 
Athletic  Committee  of  the  Harvard  College  Faculty,  that 
the  game  of  foot-ball,  as  at  present  played,  is  **  brutal," 
**  demoralizing,"  and  **  extremely  dangerous,"  is  no  more 
than  should  be  expected.  For  our  part,  we  can  only  re- 
peat what  we  have  said,  that  the  Rugby  game  is  fitted 
only  for  small  boys  and  trained  pugilists.  It  utterly  fails 
as  an  athletic  sport. 

Meaning  of  the  Word  Pharmacology. — A  corre- 
spondent writes  :  ''  Of  late  the  word  pharmacology  is  be- 
ing used.  I  would  like  to  know  its  meaning.  Webster  de- 
fines pharmacology  as  '  the  science  or  knowledge  of  drugs, 
or  the  art  of  preparing  medicines.*  The  Lancet  of  August 
16,  1884,  speaks  of  pharmacology,  or  the  physiological 
action  of  drugs.  Dunglison's  Medical  Dictionary  (1874) 
gives  no  definition  for  the  word  whatever."  The  term 
pharmacology  means  the  science  of  drugs  and  drug  ac- 


664 


THE  MEDICAL  RECORD. 


[December  13, 1884, 


tion  from  all  possible  points  of  view.  The  word  has 
lately  been  much  used  for  "experimental  pharmacology," 
or  the  study  of  the  physiological  action  of  drugs. 

The  United  States  Marine  Hospital  Service  af- 
forded relief  to  44,751  patients  during  the  year  1883-84, 
of  whom  13,078  were  treated  in  hospitals,  and  31,673 
at  the  dispensaries.  The  receipts  from  all  sources  were 
$421,348.59,  and  the  expenditures  $465,387.45. 

The  United  States  I.ife-Saving  Service  was  in- 
strumental in  saving  4,237  lives  last  year. 


^jewiexcTB  atxd  Notices. 


The  Visceral  Neuroses  ;  being  the  Gulstonian  ^Lec- 
tures on  Neuralgia  of  the  Stomach  and  Allied  Dis- 
orders, delivered  at  the  Royal  College  of  Physicians 
in  March,  1884.     By  T.  Clifford  Allbutt,  M.A., 
M.D.,  Cantab.,  F.R.S.     8vo,  pp.  103.     Philadelphia: 
P.  Blakiston,  Son  &  Co.     1884. 
The  publishers  of  this  little  volume  have  done  a  service 
in  giving  Dr.  Allbutt' s  lectures  to  the  American  public. 
The  writer  is  an  original  thinker  and  vigorous  and  charm- 
ing writer.     In  his  too  infrequent  contributions  to  med- 
ical literature  he  has  shown  that  he  touches  no  subject 
which  he  does  not  adorn.     Nor  has  he  failed  in  the  pres- 
ent case.     Attention  is  called  to  a  class  of  ailments  that 
are  not  sufficiently  recognized  and  understood  by  the 
profession  in  general.     We  need  not  go  into  any  analysis 
of  these  lectures,  since  proper  reference  was  made  to  them 
in  The  Record  when  they  first  appeared.     We  simply 
commend  them  most  heartily  to  American  readers. 

Transactions  of  the  Louisiana  State  Medical  So- 
ciety at  its  Sixth  Annual  Session,  held  at  Baton 
Rouge,  La.,  May  21,  22,  and  23,  1884. 

Proceedings  of  the  Connecticut  Medical  Society, 
1884.  Ninety-third  Annual  Convention,  held  at  New 
Haven,  May  28th  and  a9th.  New  Series,  Vol.  iii..  No. 
I.  Hartford,  Conn. :  S.  B.  St,  John,  M.D.,  Secretary, 
Hartford. 

Transactions  of  the  Medical  Society  of  the  State 
OF  California,  during  the  years  1883  ^^^  ^1884. 
Sacramento:  1884. 

Transactions  of  the  Medical  Society  of  the  State 
OF  West  Virginia*     Session  of  1884,  May  21st  and 

22d. 

Transactions  of  the  Medical  and  Chirurgical 
Faculty  of  the  State  of  Maryland.  Eighty-sixth 
Annual  Session,  April,  1884. 
These  volumes  contain  many  excellent  reports  and  pa- 
pers. We  note,  however,  that  most,  if  not  all  of  these 
have  appeared  in  various  medical  journals,  and  they  do 
not  require  comment  here. 


&ovKzsvan^i^nc!^. 


THE  VOMITING   OF   PREGNANCY— DILATA- 
TION OF  THE  CERVIX  UTERL 

To  THB  Editor  of  Thb  Medical  Rbcoko. 

Sir  :  The  report  in  your  last  issue  of  the  discussion  at  a 
late  meeting  of  the  Northwestern  Society  has  been  noted 
as  incorrect  and  incomplete  by  several  of  the  gentlemen 
who  took  part  in  it.  My  own  remarks  on  the  treatment 
of  the  vomiting  of  pregnancy  by  dilatation  of  the  cervix 
were  made  late  in  the  evening,  and,  as  they  stand,  are 
simply  unintelligible. 

I  ask  your  leave  to  correct  them  and  to  add  mention 
of  another  case  in  point.  The  report  should  be  as  fol- 
lows : 


Dr.  Chamberlain  said  that  he  read  the  paper  of  Dr. 
Copeman  when  it  first  appeared,  and  had  since  cm- 
ployed  its  methods  with  satisfaction.  He  would  also  re- 
mind the  gentleman  (Dr.  Wylie)  of  a  paper  by  Dr.  Engle- 
man,  published  in  the  "  Gynecological  Transactions." 

I  am  accustomed  to  regard  the  nausea  of  pregnancy  as, 
•for  the  most  part,  a  neurotic  phenomenon.  The  reflex 
actions  arising  from  the  uterus  seem  to  start  mostly  from 
its  cervical  portion.  This  is  the  most  important  portion 
of  the  organ.  At  birth,  and  even  up  to  the  approach  of 
puberty,  that  portion  of  the  womb  which  is  between  the 
vault  of  the  vagina  and  the  peritoneal  reflection  over  the 
bladder  and  the  rectum,  equals  in  volume  all  the  rest  of 
the  uterus. 

As  the  long  bones  develop  upward  and  downward 
from  the  diaphyses,  so  from  this  centre  the  vaginal  pot. 
tion  develops  downward  and  thefundal  portion  develops 
upward.  Through  this  area  the  uterine  arteries  and  the 
spinal  nerves  enter  the  womb,  and  here,  in  the  cervical 
portion,  is  the  centre  of  neurotic  activity.  I  have  re- 
peatedly  dilated  the  cervix  to  bring  on  delivery  in  cases 
of  convulsions,  and  have  almost  uniformly  seen  the  con- 
vulsions cease  as  soon  as  the  dilatation  was  well  ad- 
vanced. 

Repeatedly,  if  not  constantly,  when  I  have  dilated  the 
cervix  to  suppress  the  vomiting  of  pregnancy,  the  proceed- 
ing has  been  successful.  I  recall  the  case  of  a  lady  hav- 
ing a  small  fibroma  in  the  posterior  wall,  which  acted  like 
a  ball-valve  over  the  os  internum.  She  became  pregnant 
and  suffered  from  a  nausea  so  intense  and  persistent  that 
she  was  dependent  entirely  upon  rectal  alimentation.  I 
dilated  the  cervix,  the  vomiting  ceased  and  did  not  re- 
turn. 

Undoubtedly  there  are  cascs,  such  as  Dr.  Harrison  has 
cited,  where  a  structural  change  may  be  the  cause  of  the 
vomiting,  and  when,  as  Dr.  Wylie  has  said,  there  is  dis- 
ease of  the  cervical  mucous  membrane,  the  treatment 
should  be  of  the  mucous  membrane  ;  but  I  am  confident, 
nevertheless,  that  there  is  a  kind  of  spasm  at  the  os  in- 
ternum which  may  be  remedied  by  the  process  of  dilata- 
tion, and  which  is  the  cause  of  a  great  many  cases  of 
severe  vomiting  in  pregnant  women. 

Rectal  tenesmus  is  cured  often  by  forcible  dilatation  of 
the  anus,  and  tenesmus  of  the  neck  of  the  bladder  is 
often  cured  by  dilatation  of  urethral  stricture. 

The  case  in  point  mentioned  is  as  follows : 

About  three  hours  after  the  above  remarks  were  made 
I  saw  in  consultation  a  case  of  puerperal  convulsions. 
The  woman,  a  multipara,  was  expecting  confinement  in 
about  a  month,  but  had  not  notified  her  physician  until 
a  few  hours  previously,  and  then  on  account  of  intense 
cephalalgia  suddenly  developed.  There  was  some  cedema 
partial  suppression  of  urine,  which  was  heavily  loaded 
with  albumen,  and  embarrassed  respiration.  There  was 
frequent  grumous  vomiting.  There  had  been  one  severe 
and  prolonged  convulsion,  and  lesser  spasms. 

She  was  hardly  semi-conscious,  apparently  not'recog- 
nizing  what  was  going  on  about  her,  and  moaning  con- 
tinuously with  the  intense  pain  in  the  head. 

We  wished  to  bleed,  but  were  not  allowed  to  do  so.  Two 
drops  of  croton-oil  were  administered,  and  dilatation  was 
begun  with  the  fingers,  and  continued  with  Barnes*  bags. 
In  half  an  hour  it  was  so  far  advanced  that  the  largest 
bag  was  distended  with  nearly  a  pint  of  warm  water.  No 
anaesthetic  was  given.  The  convulsive  movements  ceased, 
she  lay  quiet,  and  no  longer  moaned.  Three  hours  later 
she  was  naturally  delivered  and  at  last  accounts  was  do- 
ing fairly  well.  I  have  not  personally  seen  her  since  the 
day  of  delivery. 

This  was  the  third  time  within  little  more  than  one 
year  that  I  had  met  the  same  gentleman  in  such  a  case 
of  uraemic  coma  and  convulsions.  In  all  three  cases  the 
eclamptic  phenomena  ceased  when  full  dilatation  was 
secured,  and  did  not  return. 

W.  M.  Chamberlain,  M.D. 

€8  West  Fortieth  Street,  December  6,  18P4. 


December  13,  1884.] 


THE  MEDICAL  RECORD. 


665 


il^otrtB  0t  ^ocutUs. 


NEW  YORK  ACADEMY  OF  MEDICINE. 

Stated  Mteting^  December  4,  1884. 

FoRDYCE   Barker,  M.D.,  LL.D.,  President,  in  the 
Chair. 

The  Statistical  Secretary  reported  the  death  of  Allen 
S.  Church,  M.D. 

T>K,  Joseph  E.  Winters  read  a  paper  (see  p.  645)  with 
the  following  title  : 

IS  THE  operation  OF  TRACHEOTOMY  IN  DIPHTHERITIC 
CROUP  DANGEROUS  ? — WHEN  SHOULD  THE  OPERATION 
BE   PERFORMED. 

Dr.  J.  WiLLiSTON  Wright  opened  the  discussion,  and 
said  that  he  did  not  regard  tracheotomy  as  an  especially 
difficult  operation.  He  was  well  aware  that  when  un- 
dertaken, as  it  frequently  was,  in  the  middle  of  the  night, 
perhaps  in  a  tenement-house,  by  the  light  of  a  tallow 
candle  or  a  dirty  kerosene  lamp,  with  such  assistants  as 
one  could  under  those  circumstances  obtain,  it  was  an 
operation  which  almost  every  surgeon  approached  with 
some  sense  of  misgiving,  and  especially  as  it  usually  oc- 
curred in  such  cases  in  young  children  with  a  short  neck 
and  a  deep  trachea.  These  difficulties,  however,  were  not 
so  great  but  that  they  might  all  be  surmounted  by  one 
who  pretended  to  understand  anything  of  surgery,  coupled 
with  a  cool  head  and  a  steady  hand. 

The  incision  for  the  operation  was  a  simple  one,  in- 
volving the  skin  and  fascia  chiefly.  Then  came  the 
separating  of  the  space  between  the  muscles  which  were 
in  front  of  the  neck,  and,  in  doing  this,  the  operator 
reached  a  mass  of  connective  tissue  and  veins  which,  if 
wounded,  frequently  bled  profusely.  If  the  operator  at 
that  time  was  impressed  with  the  hemorrhage  which  was 
going  on,  and  undertook  to  arrest  it  before  opening  the 
trachea,  he  would  probably  consume  the  remainder  of 
the  night  in  so  doing.  However,  if  the  case  was  not 
urgent,  it  nn'ght  be  proper  to  arrest  some  of  the  hemor- 
rhage, even  supposing  it  to  be  simply  venous.  Arterial 
hemorrhage,  if  the  incision  was  made  properly,  was  seldom 
troublesome. 

On  the  other  hand,  if  the  case  was  an  urgent  one,  one 
demanding  immediate  relief,  the  child  dying  with  as- 
phyxia, his  custom  was  to  ignore  this  venous  hemorrhage 
and  go  on  into  the  trachea,  feeling  very  certain  that,  as 
the  author  of  the  paper  had  stated,  this  venous  hemorrhage 
would  usually  stop  as  soon  as  the  knife  entered  the  trachea, 
or  at  least  as  soon  as  the  tube  was  introduced. 

Concerning  the  entrance  of  blood  into  the  trachea, 
he  had  usually  regarded  it  as  a  matter  of  no  special  im- 
portance. On  the  contrary,  it  had  seemed  to  him  to  be 
•the  very  thing  needed  to  stimulate  violent  expulsive  ef- 
forts which  rid  the  trachea  of  mucus  as  well  as  of  blood. 
In  that  sense,  therefore,  he  did  not  regard  tracheotomy 
as  either  an  especially  difficult  or  dangerous  operation. 
He  regarded  tracheotomy  in  the  adult  as  one  of  the 
simplest  operations  in  surgery.  In  the  young  child  the 
operation  was  facilitated  by  placing  under  the  neck  a 
common  wine  bottle  wrapped  in  a  napkin,  and  allowing 
the  head  to  hang  over  it. 

With  regard  to  the  isthmus  of  the  thyroid  body,  in 
operating  in  urgent  cases  he  .would  be  inclined  to  cut 
through  it  with  the  knife ;  but,  on  the  other  hand,  in 
cases  where  securing  of  time  was  not  so  much  the  ob- 
ject, he  would  surround  the  two  sides  of  it  with  a  ligature 
and  divide  the  tissues  between  the  ligatures,  as  stated  by 
Dr.  Winters.  If,  however,  the  child  was  practically  dead 
when  placed  upon  the  table,  he  would  not  stop  for  this 
mode  of  procedure. 

As  to  the  time  at  which  tracheotomy  should  be  resorted 
to,  he  was  of  the  opinion  that  it  should  be  performed  ' 


early — that  is,  as  soon  as  severe  symptoms  made  their 
appearance  which  were  not  relieved  by  ordinary  medical 
measures ;  in  that  respect  he  agreed  with  the  author  of 
the  paper.  If  the  diagnosis  of  membranous  croup,  or  of 
diphtheritic  laryngitis  was  well  made  out,  he  believed  that 
the  sooner  the  patient  had  the  opening  made  into  the 
trachea  the  better  were  his  chances  of  getting  well. 

The  operation,  in  his  judgment,  was  not  in  any  sense 
the  cause  of  death,  except,  possibly,  it  might  lead  to 
secondary  affections,  but  not  more  so  than  a  simple  in- 
cision made  elsewhere. 

His  fueling  with  reference  to  early  operation  was  so 
strong  that,  if  the  diagnosis  was  reasonably  correct  and 
he  was  unable  to  get  anyone  to  perform  the  operation 
on  one  of  his  own  children  or  a  near  friend,  he  would 
perform  tracheotomy  himself.  Still  further,  he  would 
perform  the  operation  upon  himself  under  the  same  cir- 
cumstances were  he  unable  to  get  a  surgeon  to  perform  it. 
He  had  performed  the  operation  once  with  an  ordinary 
pocket-knife  in  a  case  of  foreign  body  in  the  larynx. 

Dr.  a.  Jacobi  thought  that  the  discussion  should  not 
be  so  much  upon  the  general  subject  as  upon  the  elab- 
orate paper  of  the  evening.  The  subject  had  claimed 
the  attention  of  almost  numberless  writers  for  the  last 
two  generations,  a  fact  which  was  proved  by  Dr.  Win- 
ters' paper,  which  teemed  with  quotations  gathered  for 
the  purpose  of  proving  that  there  was  no  danger  from 
tracheotomy.  The  author  of  the  paper  had  quoted  fropi 
writers  on  both  sides  of  the  question,  but  had  rested 
upon  the  side  of  those  who  considered  that  tracheotomy 
was  not  a  dangerous  operation,  and  at  this  point  Dr. 
Jacobi  entered  a  criticism,  in  that  the  author  had  not 
stated  why  he  did  not  consider  tracheotomy  as  a  danger- 
ous operation.  We  should  know  first  what  the  dangers 
were  and  then  see  if  they  could  not  be  overcome.  Dr. 
Winters  had  searched  the  literature  of  old  Europe  appar- 
ently from  beginning  to  end,  but  had  made  mention  of 
only  one  American  operator,  namely,  Professor  Gross, 
and  in  that  instance  almost  only  for  the  purpose  of  show- 
ing that  Professor  Gross  was  guilty  of  contradictions  in 
his  own  writings,  so  much  so  that  it  was  scarcely  possible 
to  say  whether  Gross  really  regarded  the  operation  as 
dangerous  or  simple  and  easily  performed. 

Dr.  Jacobi  would  have  been  pleased  to  have  had  more 
extended  reference  made  to  American  operators ;  for  ex- 
ample, Dr.  Gay,  of  Boston,  who  published  an  excellent 
paper  on  this  subject  not  many  months  ago,  and  in  our 
own  midst  he  could  recall  excellent  papers  by  Hadden 
and  Ripley,  each  of  which  contained  a  vast  amount  of 
knowledge  and  solid  experience.  More  than  this,  there 
were  other  men  in  other  cities  who  had  performed  the 
operation,  and  had  reported  a  large  number  of  cases. 
He  thought  we  could  have  learned  something  from  the 
experience  of  these  surgeons. 

With  regard  to  the  dangers  of  tracheotomy,  the  prin- 
cipal one  was  that  it  was  usually  a  bungling  operation, 
and  by  bungling  operation  he  meant  a  bloody  operation, 
which  is  not  infrequent  in  unskilful  hands.  The  prin- 
cipal thing  in  performing  the  operation  was  to  be  as  con« 
siderate  and  slow  as  possible,  for  by  so  doing  hemorrhage 
could  be  avoided.  If  the  tracheal  cartilages  which  were 
to  be  cut  could  be  seen  distinctly  the  dangers  from  hem- 
orrhage would  be  avoided.  If  it  was  not  desirable  to 
operate  below  the  isthmus,  if  there  was  not  sufficient 
room  to  perform  the  operation  there,  Bose's  operation 
might  be  performed,  which  consisted  in  pulling  oflf  a  part 
of  the  isthmus.  Cutting  through  the  isthmus  would  give 
rise  to  some  hemorrhage,  and  to  cut  through  it  was  a 
mistake.  Nevertheless,  it  must  be  done  when  the  case 
was  an  urgent  one,  and,  under  those  circumstances,  it 
might  be  forgiven  \  but  if  there  are  two  or  three  minutes 
to  spare  the  isthmus  should  not  be  cut. 

Dr.  Jacobi  was  not  of  the  opinion  expressed  by  Professor 
Wright,  that  is,  to  cut  directly  through  the  isthmus  when  it 
bleeds.  He  had  seen  such  operations,  and  he  had  not  been 
able  to  find  the  trachea  on  account  of  the  blood,  and 


666 


THE  MEDICAL  RECORD. 


[December  13,  igg^. 


had  lost  a  patient  under  such  circumstances.  He  did 
not  regard  it  as  an  indifferent  matter  whether  blood  was 
drawn  into  the  trachea  or  not  It  was  true  the  child 
coughed  afterward,  and  threw  out  a  good  deal  of  the 
blood,  but  would  the  child  throw  out  everything  ?  No. 
Even  when  the  child  was  healthy  it  would  throw  out 
some  blood  as  late  as  ten  or  twenty  minutes  after  the 
operation,  if  all  of  it  ever  came  up.  When  blood  had 
entered  the  smallest  bronchi  it  had  the  same  influence 
which  a  small  amount  of  viscid  mucus  would  have  in  the 
same  position.  Broncho-pneumonia  in  children  was 
usually  a  consequence  of  simple  bronchial  catarrh.  In 
those  cases  the  smallest  bronchi  were  filled  with  mucus, 
and  behind  them  the  air-cells  contracted,  the  blood-ves- 
sels in  their  immediate  neighborhood  dilated,  congestion 
followed,  and  finally  broncho-pneumonia  developed. 
Therefore,  if  blood  entered  into  the  srtallest  ramifica- 
tions of  the  bronchi,  a  very  frequent  result  was  broncho- 
pneumonia and  death,  and  that  result  could  be  averted 
by  avoiding  hemorrhage,  and  hemorrhage  could  be 
prevented  by  taking  a  little  time  before  the  trachea  was 
opened,  which  in  the  large  majority  of  cases  could  be 
accomplished.    First  see  the  trachea,  and  then  cut  into  it. 

There  was  another  cause  of  danger.  From  the  resume 
of  the  literature  given  by  the  author  of  the  paper  it 
seemed  that  a  large  number  of  the  old  authors  were  op- 
posed to  the  operation,  and  a  large  number  of  modem 
authors  were  not  opposed  to  it,  and  why  ?  The  old  sur- 
geons operated  before  chloroform  was  discovered,  or 
were  afraid  to  use  it,  and  the  discovery  of  chloroform  was 
only  about  thirty  years  of  age.  Billroth  published  his 
experience  in  the  University  of  Zurich  twelve  or  fourteen 
years  ago,  in  which  he  declared  that  tracheotomy  was 
the  most  formidable  operation  which  he  had  ever  been 
called  upon  to  perform.  He  had  not  used  chloroform, 
and  that  it  was  which  made  the  operation  so  serious.  Dr. 
Jacobi  was  decidedly  of  the  opinion  that  anaesthetics 
should  be  used,  as  the  occurrence  of  death  during  the 
operation  was  much  more  rare  than  when  they  were  omit- 
ted. He  then  referred  to  cases  in  which  children  had 
died,  struggling  against  nurses  who  took  them  out  of  bed 
for  the  purpose  of  making  a  simple  nasal  injection,  and 
if  babies  were  operated  upon  without  the  aid  of  an 
anaesthetic  many  would  be  killed  who  would  have  been 
saved  had  an  anaesthetic  been  administered.  He  pre- 
ferred chloroform  decidedly  to  ether,  because  it  took  too 
long  to  bring  the  patient  under  the  influence  of  ether. 

Here,  then,  were  the  principal  dangers  :  first,  in  not 
using  chloroform,  and,  second,  from  hemorrhage. 

At  what  stage  of  croup  should  the  operation  be  per- 
formed ?  The  author  of  the  paper  had  stated  that  if  the 
diagnosis  was  correct  we  should  not  wait.  Dr.  Jacobi 
was  of  the  opinion  that  we  should  not  wait  until  we  were 
sure  that  it  was  a  case  of  membranous  croup ;  for  there 
were  some  cases  of  croup  which  were  not  membranous. 
He  would  say  that  whenever  there  was  laryngeal  stenosis 
which  would  positively  lead  to  death,  operate,  even  if 
the  diagnosis  of  the  presence  of  membrane  had  not  been 
made. 

Dr.  Jacobi  objected  to  dividing  croup  into  several 
stages,  especially  with  reference  to  the  operation  ;  for, 
in  some  cases  the  symptoms  demanded  tracheotomy  im- 
mediately. He  would  operate  when  he  knew  that  there 
was  laryngeal  stenosis,  a  considerable  amount  of  reces- 
sion in  the  supra-  and  infra-clavicular  regions  and  in  the 
region  of  the  ensiform  process,  and  when  he  knew  that 
these  symptoms  had  had  a  duration  of  several  hours,  or 
sometimes  several  days,  and  that  dyspnoea  had  been  in- 
creasing rapidly,  particularly  in  the  morning  only ;  for 
in  the  evening  the  symptoms  are  as  a  rule  aggravated ; 
when  there  was  cyanosis  and  frequent  pulse,  then  he 
would  operate  at  once  by  all  means.  Under  such  cir- 
cumstances we  should  not  ask  whether  or  not  there  was 
a  membrane  or  some  other  obstruction. 

It  was  true  that  diagnosis  should  be  clear  to  a  certain 
extent.     There  must  be,  of  course,  laryngeal  stenosis^ 


or  the  long-drawn-in  inspiration  which  alone  justified  us 
in  assuming  that  the  stenosis  was  not  in  the  larynx 
alone.  Pneumonia  was  not  a  contra-indication  of  trache- 
otomy. 

What  could  be  done  in  cases  in  which  there  was  a  general 
constitutional    diphtheritic    sepsis?      Decidedly  much 
could  be  done  under  those   circumstances.    In  such 
cases  there  was  a  strong  indication  for  the  operation,  for 
this  reason  :  as  soon  as  the  windpipe  was  opened  the 
fetid  inhalations  from  the  nose  and  throat  were  removed 
from  the  lungs,  which  was  an  immense  advantage.   A 
large  number  of  children  died  in  consequence  of  these 
fetid    inhalations.     While  formerly  constitutional  diph. 
theria,  complicating  diphtheritic  croup,  was  considerda 
contra-indication  to  tracheotomy.  Dr.  Jacobi  was  npon 
the  opposite  side,  and  believed  that  this  was  one  d  the 
principal  indications  for  the  performance  of  the  opera- 
tion.    In  other  cases  we  might  wait  a  little,  because  of 
the  benefit  which  might  accrue  from  the  use  of  internal 
remedies,  and  he  was  still  of  the  opinion  expressed  in 
his  paper  read  in  May  last,  that  benefit  could  be  derived 
from  the  use  of  mercurial  preparations.     In  cases  of 
membranous  croup  these  preparations  should  be  tried 
in  addition  to  the  measures  which  have  already  been  in 
general  use.     Since  he  had  resorted  to  the  mercurial 
treatment  he  was  positive  that  he  had  saved  a  large  num- 
ber of  patients,  and  that  his  percentage  of  recoveries 
without  tracheotomy  was  much  larger  than  it  had  ever 
been  before. 

Of  what  did  the  children  die  when  tracheotomy  was 
performed  ?  They  might  die  of  diphtheria,  but  they 
would  die  of  diphtheritic  sepsis  whether  the  trachea  was 
opened  or  not.  They  might  die  of  paralysis,  of  nephritis,  of 
hemorrhage,  and  they  might  die  in  consequence  of  ade- 
nitis with  gangrene  occurring,  perhaps,  in  such  enlarged 
glands,  with  hemorrhage  from  rupture  of  blood-vessels 
by  the  gangrenous  process.  Croupous  pneumonia  was 
not  so  infrequent  simply  as  a  complication  of  diphtheria, 
and  very  probably  due  to  the  same  cause. 

But  the  principal  causes  of  death  after  tracheotomy 
were  broncho-pneumonia,  or  oedema  of  the  lungs,  or  de- 
scending diphtheritic  membranous  process.  Children 
were  apt  to  die  of  broncho-pneumonia  two  or  three  days 
after  the  operanon.  Pulmonary  oedema  might  occur  and 
kill  within  a  few  hours  after  the  operation.  Within  the 
last  ten  or  fifteen  years  he  had  seen  a  large  number  of 
patients  die  of  descending  diphtheritic  process.  The 
process  would  descend  into  the  trachea  and  bronchi 
sometimes  to  the  third  bifurcation.  These  childi«n 
would  die  almost  at  a  certain  hour ;  that  is,  between 
fifty  and  seventy  hours  after  the  operation.  But  the 
descending  process  could  be  relieved  in  many  cases  by 
the  introduction  of  oxygen  into  the  circulation. 

In  saying  what  he  had  in  the  way  of  criticism  he 
had  also  meant  to  say  that  he  appreciated  the  value 
and  importance  of  the  paper,  one  which  was  well  worthy 
of  close  attention,  for  the  purpose  not  only  of  gathering 
material  for  criticism  but  also  valuable  information. 

Dr.  J.  Lewis  Smith  said :  "  All  who  have  seen  much 
of  .tracheotomy  are  for  the  most  part  agreed  as  to  the 
dangers  which  attend  it.  The  younger  the  child  the 
greater  the  danger,  so  that  in  infancy  the  operation  is 
more  difficult  and  dangerous  than  in  childhood.  I  have 
observed  two  conditions  which  greatly  enhance  the  dan- 
gers in  opening  the  windpipe.  One  is  the  late  perform- 
ance of  the  operation,  when  the  patient  is  nearly  moribund 
and  the  operator  is  impelled  to  operate  in  the  quickest 
possible  time  in  the  fear  that  the  patient  will  die  on  the 
table.  He  does  not  have  time  to  pick  his  way  cautiously 
between  the  blood-vessels,  consequently,  there  is  greater 
hemorrhage,  and  the  trachea  is  opened  before  the  bleeding  J 
entirely  ceases.  The  second  condition  is  when  the  op- 
erator does  not  fully  appreciate  the  difficulties  in  the  way, 
and  undertakes  the  operation  when  poorly  prepared 
with  instruments,  and  in  other  ways.  Such  a  case  was 
the  first  tracheotomy  which  I  witnessed.     Soon  after  my 


December  13,  1884.] 


THE   MEDICAL  RECORD. 


667 


^aduatioD  a  young  physician,  full  of  confidence,  met  me 
in  the  street,  and  wished  me  to  hold  a  child  while  he 
operated.  Unfortunately  the  patient  was  an  infant,  with 
short  neck  and  fleshy.  He  was  restless  during  the  cut- 
ting, and  died  from  the  abundant  hemorrhage  before  the 
trachea  was  reached.  Inexperience  and  the  lack  of 
proper  appreciation  of  the  difficulties  attending  trache- 
otomy therefore  increased  greatly  the  dangers  of  the  ope- 
ration. From  the  tenor  of  the  paper  to  which  we  have 
listened,  the  young  physician  might  be  led  to  suppose 
that  tracheotomy  is  a  simple  procedure  and  attended  by 
little  risk  or  difficulty,  but  I  would  strongly  advise  one 
who  operates  for  the  first  half  dozen  times  to  have  with 
him  a  physician  or  surgeon  who  is  familiar  with  trache- 
otomy, for  he  is  apt  to  be  confronted  in  the  operation  by 
unexpected  difficulties,  as  the  presence  and  abnormal 
distribution  of  large  blood-vessels.  In  the  city  such  help 
is  readily  obtained,  but  in  the  country  it  might  be  more 
difficult. 

"  In  considering  the  time  when  tracheotomy  should  be 
performed,  it  seems  to  me  convenient  to  recognize  two 
classes  of  cases.     When  croup  commences  in  the  begin- 
ning of  diphtheria  the  inflammation  is  active,  the  exuda- 
tion occurs  rapidly,  and  a  thick  pseudo-membrane  soon 
forms,  causing  a  laryngeal  stenosis  which  is  apt  to  increase 
from  hour  to  hour  in  spite  of  our  inhalations  and  medi- 
cines.    In  such  cases  I  think  we  all  agree  that  the  earlier 
tracheotomy  is  performed  the  better.     In  other  instances 
diphtheria  has  continued  a  few  days  and  the  acute  stage 
has  passed  when  croup  begins,  the  exudation  is  poured 
out  less  rapidly  and  less  abundantly,  the  stenosis  is  not 
so  urgent,  and  the  patient  not  infrequently,  in  the  type  of 
diphtheria  now  prevailing,  recovers  by  inhalations  and 
medicinal  treatment.     While,  therefore,  in  the  one  class 
of  cases  the  rapidly  increasing  stenosis  is  such  as  to  ren- 
der recovery  almost  impossible  without  surgical  interfe- 
rence, in  the  other  class  of  cases  the  subacute  character 
of  the  inflammation  and  the  slowness  of  the  exudative 
process  give   more  time   for   the    action   of  medicines, 
so   that  perhaps  tracheotomy  may  be  avoided.     During 
the  last  few  months  I  have  seen  two  patients  recover  from 
marked  larnygeal  stenosis  due  to  croup  commencing  at 
the  close  of  the  first  week,  or  in  the  second  week  of  diph- 
theria.    In  both  there  was  membranous  exudation  on  the 
fauces,  and  such  dyspnoea  that  the  post-clavicular  and 
infra-mammary  regions  were   depressed  on   inspiration, 
but  the  dyspncea  was  not  progressive,  the  suffering  was 
not  marked,  and  time  was  allowed  for  the  action  of  alka- 
line inhalations  and  medicinal  measures,  and  tracheotomy 
was  fortunately  avoided. 

"  If,  therefore,  there  is  marked  and  increasing  laryngeal 
stenosis,  notwithstanding  well-directed  and  energetic 
treatment,  and  the  patient  begins  to  suffer  from  lack  of 
air,  all  of  us,  I  think,  would  advise  early  tracheotomy,  but 
in  the  other  class  of  cases  it  is  proper  to  wait  and  trache- 
otomy may  not  be  necessary. 

"  The  position  taken  by  the  writer  that  we  must  be  sure. 
of  the  presence  of  a  pseudo-membrane  in  the  larynx  be- 
fore deci^ng  to  operate,  I  agree  with  Dr.  Jacobi,  does 
not  seem  to  me  well  taken.  It  is  difficult  to  inspect  the 
larynx  with  the  laryngoscope  when  the  fauces  are  much 
swollen,  and  the  stenosis  may  be  such  as  to  require 
tracheotomy  when  there  is  no  pseudo-membrane  in  the 
air-passages.  Trousseau  has  pointed  out  that  there  may 
be  even  a  faucial  pseudo-membrane  while  the  obstruc- 
tion in  the  larynx  is  due  to  the  infiltration  and  thickening 
of  the  mucous  membrane.  In  at  least  two  cases  in  the 
New  York  Foundling  A-sylum  in  which  death  occurred 
from  croup,  no  pseudo-membrane  was  found  in  the  air- 
passages,  but  thickening  of  the  mucous  and  submucous 
tissues  sufficient  to  cause  fatal  stenosis.  The  indication 
for  tracheotomy  is  the  amount  of  obstruction  and  dysp- 
noea, rather,  than  the  presence  or  absence  of  a  pseudo- 
membrane.  Those  who  believe  that  there  is  no  remedy 
for  croup  except  tracheotomy,  would  be  likely  to  advise 
the  operation  in  all  cases,  when  there  is  marked  dyspnoea, 


but  I  am .  sure  that  a  considerable  number  may  be  re- 
lieved without  tracheotomy  by  the  judicious  use  of  calomel 
in  a  few  doses  at  the  commencement,  perhaps  by  one  or 
two  doses  of  the  turpeth  mineral  to  which  our  esteemed 
President  called  attention  several  years  since,  by  the  use 
of  the  bichloride  of  mercury,  and  especially  by  the  persist- 
ent use  of  alkaline  inhalations." 

Dr.  John  H.  Ripley  had  been  interested  in  the  pa- 
per of  the  evening,  especially  as  the  author  had  taken 
a  position  quite  antagonistic  to  that  which  he  himself 
occupied.  Dr.  Winters'  position  with  regard  to  the  dan- 
gers, the  difficulties,  and  the  consequences  of  late  opera- 
tion were  opposed  to  Dr.  Ripley's  views.  In  sup- 
port of  his  own  views  with  regard  to  the  dangers  of  the 
operation,  Dr.  Winters  had  marshalled  a  large  number  of 
ancient  and  modern  men  of  foreign  countries,  some  of 
whom  had  performed  tracheotomy,  and  some  of  whom 
had  never  done  so  ;  some  of  whom  had  performed  trache- 
otomy for  croup,  and  some  of  whom  for  other  causes ; 
some  of  whom  had  performed  the  operation  in  children, 
and  others  who  had  performed  it  in  adults.  As  Dr.  Rip- 
ley understood  the  question,  it  was  not  whether  the  opera- 
tion of  tracheotomy  in  general  was  a  difficult  or  a  dan- 
gerous surgical  procedure,  but  it  was  whether  tracheot- 
omy in  children  for  croup  was  a  difficult  and  dangerous 
operation.  So  far  as  tracheotomy  generally  was  con- 
cerned, he  should  be  willing  to  put  in  a  demurrer  to  the 
position  taken  by  Dr.  Winters,  as  it  was  well  known  that 
it  was  neither  very  difficult  nor  very  dangerous. 

The  danger  in  cases  of  croup  consisted,  first,  in  the 
condition  of  the  child ;  second,  in  the  necessity  for  per- 
forming the  operation  within  a  given  length  of  time.  Dr. 
Winters  had  considered  one  danger,  and,  so  far  as  Dr. 
Ripley  had  been  able  to  discover,  he  had  touched  upon 
only  one,  or  at  least  but  very  little  upon  any  other,  namely, 
hemorrhage.  Dr.  Ripley  did  not  understand  that  hemor- 
rhage was  the  most  common  cause  of  death  during  the 
operation  of  tracheotomy.  The  operator  had  to  deal 
with  children  who  were  suffering  from  systemic  poisoning, 
from  stenosis  of  the  larynx,  often  from  infiltration  of  the 
cellular  tissue  of  the  neck,  which  was  sometimes  im- 
mensely swollen.  In  order  to  reach  the  trachea  under 
these  circumstances  the  surgeon  must  go  down  for  per- 
haps two  inches,  which  necessitated  a  good  deal  of  time 
and  a  good  deal  of  care,  and  these  little  children  were  so 
paralyzed  with  the  poison  of  diphtheria  that,  before  the 
surgeon  reached  the  trachea,  the  patients  were  liable  to 
die  from  syncope^  and  not  from  hemorrhage. 

If,  when  the  stenosis  was  very  great,  chloroform  was  ad- 
ministered, the  child  was  liable  to  die  of  apnoea ;  but  if 
chloroform  were  not  administered,  as  Dr.  Jacobi  has  prop- 
erly said,  the  child  would  die  from  paralysis  of  the  heart 
and  respiratory  muscles  incident  to  struggling. 

With  reference,  then,  to  tracheotomy  being  a  dangerous 
operation,  he  was  willing  to  go  with  the  small  majority 
made  up  of  such  gentlemen  as  Professor  Gross,  Mr. 
Holmes,  and  Professor  Billroth,  and  should  feel  satis- 
fied if  he  maintained  the  position  which  those  men  had 
taken.  He  thought  it  was  fair  to  presume  that  their 
opinions  were  based  upon  an  extensive  clinical  experi- 
ence. 

Dr.  Ripley  had  performed  tracheotomy  one  hundred 
and  ten  times,  and  had  seen  it  performed  at  least  fifty 
times  more.  He  had  also  seen  nearly  every  form  of  com- 
plication which  could  exist,  and  had  seen  all  sorts  of 
operators  make  a  trial  of  it.  He  had  assisted  several 
operators  at  their  first  operation,  and  believed  that  he 
had  been  the  means  of  saving  several  lives  by  being 
present  at  operations  performed  by  inexperienced  oper- 
ators. He  had  known  a  large  number  of  deaths  to  occur 
upon  the  table. 

He  did  not  say,  as  had  been  indicated  by  the  author  of 
the  paper,  that  tracheotomy  was  the  most  dangerous  of 
all  operations.  He  simply  said  that  tracheotomy  for 
croup  in  young  children  was  one  of  the  most  dangerous 
operations  in  surgery.     He  also  said  that  his  opinion  was 


668 


THE   MEDICAL   RECORD. 


[December  13, 1884. 


supported  by  Gross,  Holmes,  and  Jacobi.  He  also  was 
familiar  with  the  opinions  of  most  of  the  surgeons  in  this 
city,  and  knew  that  those  who  operated  a  great  deal  con- 
sidered it  as  a  general  rule  a  very  dangerous  operation. 

With  regard  to  ten  deaths  occurring  upon  the  table 
during  tracheotomy,  the  operations  were  performed  by 
seven  men,  and  four  of  those  were  gentlemen  of  remark- 
able surgical  experience,  ability,  and  coolness.  He  knew 
of  one  death  which  occurred  from  puncturing  the  internal 
jugular  vein,  and  the  patient  died  from  hemorrhage,  the 
operation  being  performed  by  one  of  the  best  surgeons 
in  New  York  City. 

He  also  knew  of  (juick  operations,  of  two  or  three 
plunges ;  in  one  the  plunge  was  into  the  spinal  column, 
in  another  the  operator  plunged  into  the  oesophagus,  and 
in  the  third  the  plunge  was  into  the  side  of  the  trachea, 
and  the  scalpel  went  completely  through  it.  Dr.  Ripley 
regarded  such  work  as  rather  reckless  surgery.  He 
thought  it  was  sufficiently  dangerous  when  the  tissues 
were  carefully  dissected  down  to  the  trachea,  and  the 
trachea  was  seen  before  it  was  opened.  The  trachea  was 
liable  to  be  displaced  by  an  enlarged  gland,  or  other 
condition,  and  he  regarded  it  as  exceedingly  dangerous 
to  endeavor  to  cut  mto  the  trachea  by  striking  it  with 
the  scalpel  in  the  median  line. 

As  regarded  early  operations,  Dr.  Winters  had  advo- 
cated strongly  the  performance  of  the  operation  early. 
As  Dr.  Ripley  had  often  said,  the  man  who  oper- 
ated early  would  have  the  greatest  success,  not  for  the 
reasons  which  Dr.  Winters  had  given,  ho^vever,  but  for 
the  reason  that  unnecessary  operations,  as  a  rule,  were 
those  which  were  performed  early.  He  had  within  the 
last  few  months  watched  ten  cases  of  diphtheritic  croup 
in  which  it  became  a  question  whether  or  not  tracheot- 
omy would  be  required,  and  in  all  the  patients  had  re- 
covered without  an  operation.  As  a  matter  of  necessity 
there  was  great  danger  of  making  a  mistake  in  diagnosis. 
It  was  often  impossible  to  differentiate  until  the  cases 
had  been  watched  for  two  or  three  days,  but  in  such 
cases  the  patients  almost  always  get  well  without  the 
operation.  It  was  true  that  the  operation  might  be  de- 
manded for  inflammatory  stenosis  of  the  larynx,  as  Dr. 
Jacobi  had  said,  but  those  cases  were  very  rare ;  they 
would  answer  very  well  to  the  picture  which  the  author 
of  the  paper  had  given  as  diagnostic  of  membranous 
croup.  Cases  of  catarrhal  laryngitis  were,  as  a  rule,  not 
accompanied  by  a  great  amount  of  difficulty  in  expira- 
tion, but  in  certain  cases  there  would  be  difficulty  in  both 
inspiration  and  expiration,  and  in  these  cases  the  patient 
would  get  well  without  the  operation.  Besides,  there 
was  a  certain  number  of  cases  of  diphtheritic  croup  in 
which  the  patients  would  recover  without  either  remedies 
or  operation.  Hence  it  was  that  there  were  so  many 
specifics  for  croup,  because  in  a  certain  proportion  of 
cases  of  croup  the  patients  would  recover  without  any 
treatment,  especially  if  the  air  of  the  room  was  kept 
moist  with  steam. 

Concerning  the  effects  of  delaying  the  operation, 
he  had  been  complimented  by  Dr.  Winters  with  the 
statement  that  his  argument  was  illogical  because  he  had 
advocated  a  late  operation,  and  then  went  on  to  say  that 
he  had  been  called  to  operate  for  croup  and  found  the 
children  dead  when  he  reached  the  place.  Dr.  Ripley 
was  unable  to  see  anything  specially  illogical  in  the 
statement  which  he  made,  and  thought  that  if  the  gentle- 
men who  read  his  paper  would  follow  the  course  that  he 
there  advocated,  they  would  come  out  all  right.  With 
reference  to  these  cases,  in  one  instance  the  doctor  had 
not  seen  the  patient  for  a  number  of  hours,  and  in  one 
case  for  twelve  hours.  If  Dr.  Ripley  had  advocated  any- 
thing in  his  paper,  it  was  that  all  such  ca^es  should  be 
watched  very  closely. 

If  Dr.  Winters'  causes  of  death  after  late  operations 
were  really  such,  then  they  must  be  those  which  he 
stated,  such  as  pneumonia  and  extensive  bronchitis.  Dr. 
Ripley  thought  that  if  there  was  any  fact  in  scientific 


medicine  easily  demonstrated,  it  was  that  stenosis  of  the 
larynx,  or  stenosis  of  any  part  of  the  respiratory  organs 
before  the  air- vesicles  were  reached,  which  was  not  com- 
plete, gave  rise,  not  to  congestion  of  the  lungs,  but  to 
ancemia  of  the  lungs,  which  can  be  easily  ascertained  by 
physical  signs.     Broncho-pneumonia,  as  claimed  by  both 
Dr.  Jacobi  and  Dr.  Winters,  was  not  found,  but  anairaia  * 
of  the  lungs   and   certain  areas  of  collapse  \^hich  had 
been  produced  by  plugging  up  the  bronchi  leading  to 
these  collapsed  portions  of  lung  tissue.    If  that  was  true, 
then  prolonged  stenosis  of  the  Jarynx  did  not  give  rise  to 
congestion  of  the  lungs,  and  hence  delayed  operations 
were  not  dangerous  on  account  of  broncho-pneumonia 
which  might  follow.     Dr.  Ripley  then  referred  to  anaa- 
topsy  recently  made  by  Dr.  Maxwell,  in  a  case  of  diph- 
theritic croup,  in  which  were  found  membrane  cxten&g 
downward  as  far  as  the  third  bifurcation  of  the  brondn, 
with  two  or  three  large  areas  of  collapse,  and  no  broncho- 
pneumonia whatever.     Dr.  Ripley  then  stated,  as  he  had 
done  previously,  and  he  now  has  the  records  of  about 
twenty  autopsies,  that  in  not  a  single  instance  had  there 
been  found  sufficient  pneumonia  to  produce  death.   The 
most  common  cause  of  death,  whether  in  the  early  or 
late  stage,  was  bronchial  croup.     Trace  the  bronchi  out 
and   it  would  be  found  that   the  membrane  extended 
sometimes  as  far  as  the  fourth  or  fifth  bifurcation,  but 
before  the  membrane  lined   the  tubes   throughout  the 
child  must  die  of  suffocation. 

There  were  also  other  causes '  of  death,  such  as  ne- 
phritis, which  killed  in  quite  a  number  of  cases;  also 
respiratory  or  cardiac  paralysis,  or  both.  These  were 
the  three  principal  causes  of  death  after  tracheotomy. 

Carbonic  acid  poisoning  had  no  tendency  to  increase 
the  formation  of  membrane. 

When  the  child  did  not  have  retraction  of  the  chest- 
walls  in  respiration  he  did  not  perform  tracheotomy. 

In  conclusion  he  simply  wished  to  impress  what  he 
had  stated  with  regard  to  the  causes  of  death  upon  the 
table,  namely,  that  hemorrhage  was  one  of  the  most  in- 
frequent, and  further,  that  he  regarded  it  as  eminently 
proper  for  an  inexperienced  man  to  call  to  bis  aid,  if  pos- 
sible, an  experienced  man  when  the  operation  was  per- 
formed. 

Dr.  Winters,  in  closing  the  discussion,  remarked, 
with  reference  to  Dr.  Jacobi's  criticism,  that  he  had 
quoted  many  American  writers  as  well  as  Professor  Gross. 

Regarding  the  entrance  of  blood  into  the  trachea, 
there  had  been  a  great  misconception  concerning  the 
performance  of  tracheotomy.  Tracheotomy  properly 
performed  was  almost  bloodless.  He  had  seen  the 
operation  performed  for  the  first  time  very  often,  and 
had  seen  it  done  better  than  it  was  usually  executed  by 
specialists,  for  the  reason  that  the  operators  usually  pro- 
ceeded with  more  care,  and  secondly,  that  the  specialist 
was  not  accustomed  to  watching  the  disease  day  by  day, 
was  terrified  by  the  appearance  of  the  patient,  and 
thought  that  preservation  of  life  depended  upon  making 
an  opening  into  the  trachea  quickly.  Dr.  Winters 
thought  the  operation  should  be  performed  by  the  man 
accustomed  to  sit  by  the  bedside  and  watch  the  progress 
of  the  disease,  and  who  therefore  knows  that  it  matters  not 
if  he  complete  the  operation  in  one  or  twenty  minutes. 

How  should  tracheotomy  be  performed  in  order  to  be 
bloodless  ?  After  the  incision  through  the  integument 
was  made  the  scalpel  should  be  put  aside  and  not  taken 
up  again  until  the  trachea  was  laid  bare.  The  separation 
of  the  tissues  might  be  made  with  two  pairs  of  forceps, 
or  it  could  be  done  readily  with  the  end  of  a  pair  of  or- 
dinary scissors.  If  any  portion  of  the  fascia  could  not 
be  torn  it  could  be  raised  on  a  director  and  divided, 
preferably  by  a  pair  of  dull  scissors,  after  being  carefully 
inspected.  When  the  operation  was  performed  in  this 
manner  care  was  not  required  with  reference  to  the  en- 
trance of  blood  into  the  trachea. 

Dr.  Jacobi  had  said  that,  when  blood  entered  the 
trachea  and  the  bronchi,  it  might  cause  bronchitis  and 


December  13,  1884.] 


THE   MEDICAL   RECORD. 


669 


broncho-pneumonia.  Dr.  Winters  regarded  this  as  the 
view  formerly  advocated  by  Niemeyer  in  treating  of 
bronchial  hemorrhage,  and  thought  that  it  had  been 
almost  entirely  exploded;  mdeed,  Niemeyer  retracted 
it  before  his  death.  It  was  not  possible  foi  blood  to 
get  into  the  small  bronchi,  and  produce  broncho-pneu- 
monia. If  a  small  quantity  of  blood  got  into  the  trachea 
and  was  left  there,  the  operation  was  not  completed. 
The  operation  was  incomplete  until  every  portion  of 
blood  had  been  expelled  from  the  trachea  by  titillation 
with  a  feather  or  other  means. 

Dr.  Jacob!  had  also  stated  that  the  older  writers  were 
opposed  to  the  operation  of  tracheotomy  because  it  was 
before  the  discovery  of  chloroform,  but  Dr.  Winters 
thought  that  the  quotations  which  he  had  made  were  suf- 
ficient answer  to  that  statement.  Billroth  had  been  re- 
ferred to  as  opposing  the  operation,  more  especially  be- 
cause he  had  performed  it  without  chloroform.  On  this 
point  Dr;  Winters  stated  that  Billroth  had  performed 
the  operation  only  twelve  times  so  far  as  he  had  been 
able  to  find  on  record.  Concerning  chloroform,  he  had 
not  supposed  there  was  any  question  concerning  the 
propriety  of  using  it  ordinarily  in  tracheotomy,  nor  did 
he  suppose  there  was  any  marked  difference  of  opinion 
as  to  which  was  preferable,  chloroform  or  ether.  Ether 
produced  irritation  and  congestion  of  the  air-passages 
sometimes  amounting  to  acute  inflammation. 

With  reference  to  membranous  croup  having  stages. 
Dr.  Winters  did  not  use  the  word  stages  with  reference 
to  croup,  except  as  quoted  from  Sann6,  of  Paris.  He 
agreed  with  'Dr.  Jacobi,  that  these  stages  could  not  be 
always  recognized. 

Dr.  Jacobi  had  also  alluded  to  the  use  of  mercury  in 
the  cure  of  croup.  That  bichloride  of  mercury  was  a 
germicide  or  an  anti-fermentative  in  the  cure  of  diph- 
Sieria  Dr.  Winters  did  not  believe.  It  was  not  possible 
for  bichloride  of  mercury  to  be  introduced  into  the  blood 
in  sufficient  quantity  to  act  in  either  way.  In  the  first 
place,  it  was  given  in  small  quantities  frequently  re- 
peated, and  it  was  rapidly  eliminated,  and  if  elimination 
was  interfered  with  it  induced  one  of  two  things,  either 
vomiting  or  purging.  Therefore  there  was  not  sufficient 
of  the  remedy  accumulated  in  the  blood  to  act  as  either 
a  germicide  or  an  anti-fermentative.  Was  it  possible  to 
get  the  jgermicidal  effect  of  the  remedy  by  its  internal 
administration?  Positively,  no.  It  had  no  other  action 
than  that  of  a  simple  tonic,  and  its  action  in  the  cure  of 
croup  was  precisely  the  same  as  that  of  iron,  a  remedy 
which  it  would  never  supersede.  As  to  bichloride  of 
mercury  having  any  influence  in  producing  resolution 
of  the  membranous  exudate,  it  had  no  more  action  than 
any  other  mercurial  salt. 

With  reference  to  the  extension  of  diphtheria  to  the 
bronchiy  if  diphtheria  extended  into  the  trachea  and 
bronchi  it  almost  always  did  so  before  the  performance 
of  tracheotomy.  Dr.  Winters  did  not  think  that  a  post- 
mortem record  couJd  be  found  which  would  tend  to  show 
that  the  membranous  exudation  of  diphtheria  appeared 
in  the  trachea  and  bronchi  offer  the  performance  of  tra- 
cheotomy, when  it  did  not  exist  previous  to  the  operation. 
The  extension  of  the  disease  was  by  its  propagation 
downward,  and  in  those  cases  in  which  it  was  found 
death  occurred  within  a  comparatively  short  period, 
before  sufficient  time  had  elapsed  for  the  disease  to  ex- 
tend there  after  the  performance  of  the  operation. 

As  regarded  Dr.  Smith's  statement  concerning  the 
necessity  of  assistance  to  one  inexperienced  in  the  per- 
formance of  tracheotomy,  Dr.  Winters  could  not  feel 
that  it  was  essential,  and  Dr.  Smith  himself  had  admitted 
that  under  certain  circumstances  in  the  country  it  was 
not  necessary.  What  can  be  done  in  the  country  can 
be  done  in  the  city. 

Tubage  of  the  larynx  dates  from  Hippocrates,  although 
Dr.  Winters  was  not  able  to  state  that  it  was  then  ap- 
plied. It  had  been  practised  in  France  a  great  deal,  but 
it  wa^  entirely  out  of  use,  and  no  one  in  France,  experi- 


enced in  the  treatment  of  membranous  croup,  would 
think,  at  the  present  time,  of  tubing  the  larynx. 

Dr.  Ripley  had  stated  that  many  of  the  gentlemen 
whom  he  had  quoted  had  never  performed  tracheotomy. 
In  answer  to  this,  Dr.  Winters  said  he  had  quoted 
one,  possibly  two,  gentlemen  who  had  never  performed 
tracheotomy,  but  almost  all  the  quotations  had  been 
made  from  men  who  had  performed  the  operation  hun- 
dreds of  times,  and  almost  all  of  them  had  performed 
the  operation  in  diphtheritic  croup.  In  regard  to  Dr. 
Gross,  his  book,  at  least,  did  not  show  that  he  had  ever 
performed  tracheotomy  for  diphtheritic  croup.  Dr.  Rip- 
ley apparently  confounded  the  dangers  of  the  operation 
with  the  dangers  of  the  disease^  and  said  that  the  condi- 
tions which  render  the  operation  needful  made  it  dan- 
gerous. Dr.  Winters  said  that  the  operation  itself,  per- 
formed with  care,  was  not  dangerous.  Any  man  who  was 
competent  to  practise  medicine  could,  in  a  time  of  emer- 
gency, without  a  single  surgical  instrument,  perform 
tracheotomy  in  diphtheritic  croup  in  a  young  child  with 
a  short,  thick,  swollen  neck,  with  absolutely  no  danger 
to  the  patient.  Such  a  man  generally  has  a  knife  with 
which  he  can  make  an  incision  through  the  integument, 
and  with  an  ordinary  pair  of  scissors  he  can  work  his  way 
to  the  trachea  with  the  loss  of  less  than  a  drachm  of  blood. 
When  the  trachea  has  been  clearly  exposed  he  can  open  it 
with  a  penknife,  and  he  can  then  hold  the  trachea  open  with 
two  bent  pins  and  a  tape  going  round  the  neck,  as  one  sur- 
geon did,  and  saved  the  child^s  life.  Any  man  who  was 
prepared  to  undertake  tracheotomy  in  that  way  was  far 
superior  to  the  specialist  who  used  a  large  array  of  instru- 
ments, and  with  one  incision  laid  bare  the  trachea. 

Concerning  deaths  upon  the  table.  Dr.  Ripley  still 
insisted  upon  that  occurrence  as  being  an  indication 
of  the  danger  of  the  operaton.  When  death  occurred 
upon  the  operating-table  it  was  not  due  to  the  operation, 
unless  performed  with  haste  and  carelessness.  It  was 
always  due  to  either  carelessness  or  late  performance  of 
the  operation.  Again,  Dr.  Ripley  said  that  by  resorting 
to  the  operation  early  we  should  operate  in  cases  where 
it  was  not  necessary.  To  that  point  Dr.  Winters  had  al- 
luded in  his  paper,  and  it  was  there  that  the  question  of 
diagnosis  was  introduced.  That  was  the  reason  why 
the  operation  should  be  in  the  hands  of  the  general  prac- 
titioner, because  he  was  a  better  diagnostician  in  croup 
than  the  surgeon,  who  was  not  accustomed  to  watch  the 
progress  of  the  disease.  A  man  who  had  watched  many 
cases  of  croup  could  be  very  sure  of  his  diagnosis. 

With  reference  to  catarrhal  laryngitis,  spasm,  and 
oedema.  Dr.  Winters  impressed  the  fact  spoken  of  by  Dr. 
Ripley,  that  where  expiration  was  free  there  was  no 
membrane  in  the  larynx ;  but  the  moment  you  have  ob- 
struction, prolonged  audible  expiration,  voice  suppressed 
to  a  whisper,  there  was  membrane  in  the  larynx  ;  nothing 
else  would  produce  that  symptom. 

Regarding  prolonged  obstruction  to  inspiration.  Dr. 
Ripley  had  said  that  it  did  not  produce  congestion  of 
the  lungs.  That  view  would  not  bear  close  examination. 
Any  one  familiar  with  the  physiology  of  respiration 
knew  that  as  soon  as  interference  with  the  inspiratory 
act  occurred  embarrassment  of  the  pulmonary  circula- 
tion followed,  and  with  this  damming  back  of  blood  upon 
the  heart,  a  final  result  was  a  weakened  heart-force,  de- 
layed circulation,  diminished  aspiration  force,  and  passive 
congestion  of  the  pulmonary  vessels,  and  to  this  there  was 
no  exception  in  protracted  stenosis  of  the  larynx.  No 
man  could  prove  by  autopsies  upon  record  that  it  did 
not  occur  in  every  case  of  protracted  croup  where 
tracheotomy  had  not  been  performed.  Dr.  Winters  had 
examined  the  records  of  hundreds  of  cases,  and  had  found 
passive  congestion,  accumulation  of  mucus  in  the  bron- 
chi, pulmonary  collapse,  and  when  the  condition  had  ex- 
isted a  little  longer  he  had  found  congestion  of  the  lungs 
and  pulmonary  oedema,  all  the  changes  which  exist  in  a 
case  of  ordinary  broncho-pneumonia.  Dr.  Ripley  had 
also  spoken  of  the  analogy  existing  between  astiima  and 


670 


THE   MEDICAL  RECORD. 


[December  13,  li^^ 


croup  so  far  as  the  lungs  were  concerned.  Dr.  Winters 
said  there  was  no  analogy  whatever  existing  between  the 
two  conditions. 

Dr.  L.  Elsberg  wished  to  say  a  word  in  defence  of 
the  memory  of  his  old  teacher,  Professor  Gross,  who  had 
taught  that,  although  the  general  operation  of  tracheotomy 
was  perfectly  simple  and  not  difficult  to  perform,  there 
were  circumstances  which  rendered  it  one  of  the  most 
serious  and  formidable  operations  in  surgery.  It  was  not 
true,  as  Dr.  Winters  had  stated,  that  Professor  Gross  had 
not  performed  the  operation  for  diphtheritic  croup.  Dr. 
Elsberg  heartily  sympathized  with  the  general  drift  of  Dr. 
Winters'  paper,  and  said  that  he  had  previously  placed 
himself  upon  record  with  the  statement  that  any  medical 
man  worthy  of  the  name  of  physician  should  be  table  to 
perform  tracheotomy. 

Dr.  Winters  remarked  that  no  one  would  bow  lower 
or  more  reverently  than  he  to  the  memory  of  the  late 
Professor  Gross,  but  he  believed  it  to  be  eminently 
proper  to  criticise  some  of  the  statements  which  this 
justly  distinguished  author  had  made  in  his  work  on 
**  Foreign  Bodies  in  the  Air-passages,"  and,  so  far  as  his 
book  was  concerned,  there  did  not  exist  in  it  any  evi- 
dence that  Professor  Gross  had  ever  performed  tracheot- 
omy for  diphtheritic  croup. 
.  The  Academy  then  adjourned. 


NEW   YORIC  PATHOLOGICAL   SOCIETY. 
Stated  Meeting,  November  12,  1884. 

R.  E.  Van  Gieson,   M.D.,   Vice-President,    in  the 
Chair. 

Dr.  R.  W.  Wilcox  presented  a  specimen  of 

cancer  of  the   breast — SCIRRHOUS  MAMMA — 

which  he  removed  October  16,  1884. 

Mrs.  W ,  fifty  years  of  age,  with  excellent  family 

history,  and  the  mother  of  three  children,  had  had  pain 
in  the  left  side  of  her  chest  for  the  last  three  years.  As 
the  pain  was  increased  on  deep  inspiration  she  inferred 
that  it  was  due  to  some  respiratory  or  rheumatic  affection, 
and  applied  a  plaster.  When  she  removed  this  plaster  she 
noticed  a  small  lump,  about  the  size  of  the  end  of  her  in- 
dex-finger, in  the  left  breast,  below  the  nipple.  Within 
the  next  six  months  she  began  to  have  stinging,  itching, 
and  drawing  pains  at  intervals,  but  more  especially  dur- 
ing the  few  days  previous  to  the  menstrual  period.  Dur- 
ing the  last  year  retraction  of  the  nipple  has  been  noticed. 
The  pain  gradually  increased  until  it  became  constant 
and  severe,  interrupting  the  sleep.  Had  no  symptoms 
during  lactation.  Has  not  yet  reached  the  menopause. 
Axillary  glands  not  affected. 

The  report  of  the  examination  of  the  specimen,  by  Dr. 
H.  C.  Coe,  is  as  follows  : 

Gross  appearance, — Specimen  includes  the  entire  mam- 
ma, which  is  of  nearly  normal  appearance,  though  the 
nipple  is  small,  fixed,  and  slightly  retracted.  Below  the 
nipple  is  a  hard  mass  about  the  size  of  a  hazel-nut.  On 
section  the  gland  is  found  to  be  overgrown  by  adipose 
tissue.  In  the  centre  of  the  mass,  just  beneath  the  nipple, 
is  a  firm,  hard,  fibrous  mass,  which  is  attached  to  and  in- 
volves the  base  of  the  nipple.  Strong  bands  of  fibrous 
tissue  extend  from  the  periphery  of  the  gland  to  this  nod- 
ule. 

Microscopic  examination. — The  central  mass  is  found 
to  be  largely  made  up  of  fibrous  tissue.  Some  sections 
show  an  entire  absence  of  cellular  elements,  others  are 
filled  with  scattered  groups  of  epithelial  cells,  having  a 
distinct  alveolar  arrangement.  No  signs  of  degenerative 
changes  throughout  the  growth. 

Dr.  Garrish  asked  if  any  member  had  known  a  pa- 
tient to  live  ten  years  after  removal  of  a  breast  for  scir- 
rhus.  The  late  Dr.  Valentine  Mott  had  made  the  asser- 
tion that  no  patient  could  live  more  than  six  years  after 
removal  of  the  breast  for  cancer. 


Dr.  Wveth  referred  to  one  case  in  which  the  padcnt 
had  lived  seven  years  after  removal  of  the  cancerous 
breast.  In  his  case  there  had  been  a  number  of  opera, 
tions. 

Dr  Carpenter  referred  to  a  case  in  which,  eight  years 
ago,  he  assisted  in  removing  a  tumor  of  the  breast,  which 
microscopical  examination,  made  by  Dr.  Delafield  and 
himself,  determined  to  be  cancer.  There  had  beenn) 
recurrence  of  the  disease. 

Dr.  George  A.  Dixon  presented  specimens  of 

pachymeningitis  interna  hemorrhagica,  with  cfre. 

BRAL   hemorrhage, 

accompanied  by  the  following  history  : 

J.  C ,  thirty-three  years  of  age  ;  Ireland  ;  fireman, 

admitted  to  Charity  Hospital,  October  27,  1884,  Family 
history  :  Negative  \  previous  history  :  Patient  has  been  a 
hard  drinker  for  some  years,  his  work  has  been  fireman 
on  board  ship.  Gives  no  history  of  any  trouble  up  to 
six  months  ago.  Then,  while  at  Madagascar,  was  attacked 
with  what  he  called  "  chills  and  fever."  Would  have  a 
chill  v^hich  was  quite  severe,  followed  by  headaclie  and 
fever,  lasting  until  evening ;  these  symptoms  returned 
each  day.  He  complains  of  some  epigastric  pain,  and 
has  vomited  some  blood.  Had  a  small  hard  sore  on  penis 
three  months  ago,  followed  by  an  eruption.  Had  gonor- 
rhoea some  years  ago,  and  has  discharge  now. 

Present  condition,  October  27,  1884. — Complains  of 
above  symptoms  and  describes  headache  as  burning  in 
character  and  occurring  over  front  part  of  head.  Has  a 
pain  in  his  back  and  also  in  epigastric  region.  Appetite 
poor ;  bowels  regular  ;  has  no  trouble  in  passing  urine. 
Walks  around  ward. 

October  30th. — Patient  is  rational  and  seems  to  be 
doing  fairly  well.  Physical  examination  reveals  nothing 
except  slight  enlargement  of  liver. 

November  3d. — To-day  I  saw  patient  for  the  first  time, 
having  just  come  on  the  service.  Patient  was  asleep, 
was  easily  aroused,  but  was  drowsy.  His  pupils  were  a 
very  little  enlarged  equally.  Could  shut  both  eyes  tightly, 
and  either  separately.  Mouth  could  be  well  drawn  to 
either  side  ;  tongue  was  protruded  straight.  Complained 
of  soreness  on  percussion  over  skull ;  said  that  on  October 
27,  1884,  he  had  fallen  down  stairs,  striking  on  leftside 
of  head  ;  no  fracture  could  be  detected.  The  grasp  of 
the  right  hand  was  weaker  than  that  of  the  left.  Got  out 
of  bed  and  walked^  without  difficulty,  but  had  hemiplegic 
gait  in  right  leg  ;  stood  well  with  feet  together  when  his 
eyes  were  shut,  also  on  left  foot,  but  could  not  stand  on 
right  foot.  The  right  patellar  tendon  reflex  was  exag- 
gerated, there  was  no  ankle  clonus,  and  the  cremastenc 
reflexes  seemed  equal  on  the  two  sides.  There  was 
slight  loss  of  sensation  over  entire  right  side.  There  was 
no  trouble  with  either  bladder  or  rectum.  Speech  was  slow 
and  drawling ;  patient  seemed  to  understand  questions 
perfectly. 

Diagnosis. — Either  meningeal  hembrrhage,  syphilitic 
tumor,  cerebral  hemorrhage,  or  pachymeningitis  hemor- 
rhagica. 

Treatment, — Potass,  iodid.,  grs.  x.  ter.  in  die.,  to  be 
rapidly  increased.     Hydrarg.  biniod.,  gr.  ^  ter.  in  die. 

November  5th. — Patient  sleeps  most  of  the  time  and 
is  more  stupid,  was  delirious  last  night ;  has  difficulty  b 
passing  urine. 

November  7th, — Has  had  muttering  delirium  con 
stantly  since  last  note,  continually  says,  "  My  head  is 
broken."  Could  not  be  aroused  this  morning,  and  died 
at  3.45  P.M.,  just  after  vomiting  a  quantity  of  yellowish 
fluid. 

Autopsy^  by  Dr.  Banks,  house-physician,  twenty-four 
hours  after  death.  Heart,  normal,  weighs  twelve  and 
one-half  ounces;  liver,  fatty  and  enlarged,  sixty-nine 
ounces ;  spleen,  enlarged  and  soft,  six  and  one-half 
ounces ;  kidneys,  normal,  weigh  twelve  ounces ;  lungs, 
hypostatic  congestion  at  posterior  border,  otherwise  nor- 
mal, fifty-seven  ounces.     On  removing  scalp  a  contused 


December  13,  1884.] 


THE   MEDICAL  RECORD. 


671 


spot  was  seen  over  left  parietal  bone.  There  was  no 
fracture  of  skull.  Brain  was  carefully  removed  and  sent 
to  me.  The  brain  is  well  developed,  there  is  slight 
flattening  over  left  hemisphere.  The  inner  surface  of  the 
dura  mater,  covering  the  upper  surface  of  the  left  hemi- 
sphere, is  covered  by  a  false  membrane,  in  the  meshes  of 
which  are  extensive  hemorrhages.  The  measurements 
of  this  false  membrane  are,  antero-posteriojly,  six  and 
one-half  inches ;  laterally,  two  and  one-half  iriches,  and 
one-quarter  of  an  inch  in  depth.  There  are  punctate 
hemorrhages  in  the  meshes  of  the  pia  mater  underneath 
this  area,  and  around  are  pigmentary  spots.  This  false 
membrane  covers  the  posterior  aspect  of  the  first  and 
second  frontal  convolutions  in  front,  to  the  comer  of  oc- 
cipital lobe  behind,  and  covering  upper  two-thirds  of 
ascending  frontal  and  parietal  convolutions,  also  parietal 
lobe.  There  is  a  recent  hemorrhage  in  the  left  hemi- 
sphere, beneath  superior  and  inferior  parietal  convolutions, 
measuring,  antero-posteriorly,  one  inch;  laterally,  one 
and  one-fourth  inch,  the  cavity  of  which  would  hold  an 
English  walnut  This  hemorrhage  is  situated  in  the 
internal  capsule.  The  arteries  at  the  base  were  normal ; 
no  miliary  aneurisms  could  be  detected. 

The  severe  pain  in  the  head,  the  history  of  alcoholism, 
the  fall  ten  days  before  death,  and  the  stupor  with  slight 
paresis  on  right  side,  were  points  to  my  mind  in  favor  of  one 
of  the  four  conditions  I  have  named,  with  the  probability 
that  it  was  a  meningeal  hemorrhage,  pachymeningitis,  or 
possibly  a  syphilitic  tumor  occurring  early  in  disease. 
Unfortunately  no  temperature  was  taken,  so  that  cerebral 
hemorrhage  could  not  be  excluded  when  I  first  saw  him. 
The  points  of  interest  are  :  the  age  of  patient,  the  recency 
of  the  syphilitic  attack,  the  absence  of  any  well-marked 
head  symptoms  until  three  days  before  death,  the  stupor 
occurring  then  and  increasing  rapidly,  patient  becom- 
ing comatose  in  afternoon,  and  the  appearance  of 
the  haematoma — the  process  having  been  going  on  for 
years  probably.  It  seems  to  me  that  the  cerebral  hemor- 
rhage occurred  only  three  days  before  death,  at  the  time 
the  patient  became  comatose,  and  this  apoplexy  was  the 
direct  cause  of  death.  It  is  very  unfortunate  that  I 
coald  find  no  friends  of  deceased  to  obtain  a  good  previ- 
ous history.  The  hemorrhage  was  probably  due  to 
miliary  aneurisms,  although  none  were  found,  and  the 
arteries  at  the  base  were  normal,  as  well  also  the  kidneys 
and  heart. 

Dr.  Seguin  remarked  that  the  case  was  interesting  on 
account  of  the  slight  symptoms  connected  with  the  pachy- 
meningitis, which  was  in  accord  with  what  hs  had  seen 
in  two  cases  in  which  the  symptom  was  mainly  headache 
of  different  forms — not  burning  pain,  but  severe  head- 
ache. 

In  the  first  case  the  patient  became  gradually  comatose 
without  paralytic  manifestations,  and  the  autopsy  showed 
a  thick  hemorrhagic  clot  over  both  hemispheres. 

In  the  second  case  the  first  symptom  was  headache, 
not  localized,  but  severe  pain,  and  then  there  occurred 
rather  suddenly  clonic  spasms  in  the  face  and  hand  of 
one  side,  and  also  paresis  of  that  side,  after  which  the  pa- 
tient became  gradually  more  and  more  comatose,  and 
died  without  paralysis. 

In  both  cases  the  pupils  were  contracted.  In  the  sec- 
ond case  the  quantity  of  blood  within  the  cranial  cavity 
was  so  enormous  that  the  hemispheres  were  concave  at 
the  autopsy,  and  when  the  dura  was  pricked  the  blood 
spurted  out  to  a  great  distance  ;  yet  there  was  no  marked 
paresis.     There  was  no  diagnosis  in  either  case. 

With  reference  to  miliary  aneurisms,  it  is  necessary  in 
searching  for  them  to  sacrifice  the  specimen.  The  brain 
should  be  placed  in  water  and  allowed  to  decompose, 
when  the  blood-vessels  can  be  brushed  out  and  the  aneur- 
isms easily  detected. 

Dr.  Peabody  remarked  that  the  case  was  further  in- 
teresting in  the  comparative  youth  of  the  patient  It  was 
rather  unusual  for  cerebral  hemorrhage  to  occur  at  this 
age,    if  the  patient  had  normal  kidneys  and  heart.     It 


had  occurred  to  him  several  times  to  find  cerebral  hemor- 
rhage in  young  persons,  and  in  one  case  the  patient  was 
a  boy  nineteen  years  of  age.  In  that  instance,  however, 
there  was  a  congenital  narrowing  of  the  aorta. 

With  reference  to  pachymeningitis  hemorrhagica,  he 
had  observed  that  the  disease  may  exist  without  producing 
any  symptoms  whatever  until  a  large  hemorrhage  takes 
place.  He  had  frequently  found  the  lesion  of  pachymen- 
ingitis hemorrhagica  to  the  extent  of  the  formation  of 
numerous  layers  up  to  fully  formed  connective  tissue,  in 
which  repeated  small  hemorrhages  had  occurred,  as  evi- 
denced by  numerous  collections  of  blood  pigment,  and  in 
which  no  symptoms  whatever  had  been  given  during  the 
life  of  the  patient. 

It  had  also  occurred  to  him  to  find  cases  in  which  the 
hemorrhage  had  been  large,  and  the  symptoms  had  been 
very  pronounced,  but  they  were  merely  the  symptoms  of 
pressure  upon  the  surface  of  the  brain. 

Dr.  Van  Santvoord  thought  the  traumatism  in  Dr. 
Dixon's  case  should  have  a  little  more  stress  laid  upon.it 
than  it  had  received.  He  remembered,  when  an  interne 
in  Bellevue  Hospital,  that  quite  a  large  number  of  cases 
of  intoxication  were  admitted,  presenting  no  symp- 
toms except  semi-stupor ;  but  the  patients  finally  became 
comatose  and  died  without  marked  paresis  or  paralysis. 
At  the  autopsy  there  was  found  fracture  at  the  base  of 
the  skull,  but  the  fatal  lesion  seemed  to  be  surface  hemor- 
rhage, adherent  or  not  to  the  dura  mater.  He  remem- 
bered one  case  in  particular,  that  of  a  woman,  who  fell 
and  struck  her  head  against  a  hard  resisting  substance. 
At  the  autopsy  there  was  found  extensive  pachymeningi- 
tis, with  quite  a  recent  hemorrhage  under  a  layer  of  mem- 
brane on  both  sides  of  the  falx.  Jn  that  case  it  was  a 
question  whether  the  condition  dated  from  the  fall  or 
whether  the  hemorrhage  only  was  excited  by  the  fall.  In 
Dr.  Dixon's  specimen  the  pachymeningitis  presented  the 
appearance  of  being  of  recent  occurrence. 

Dr.  Dixon  said  a  point  against  the  last  statement 
made  by  Dr.  Van  Santvoord  was  the  fact  that  there  was 
a  good  deal  of  pigment  around  the  hemorrhage,  which 
must  have  been  of  old  date,  and  there  were  several  lay- 
ers into  which  it  was  evident  that  hemorrhage  had  been 
taking  place  from  time  to  time. 

Dr.  Seguin  asked  Dr.  Peabody  if  he  had  been  able  to 
make  sure  that  headache  was  not  present  in  his  cases. 

Dr.  Peabody  said  he  was  not  entirely  sure  of  the  ab- 
sence of  headache,  for  the  reason  that  the  cases  were  all 
hospital  cases.  But  he  was  able  to  say  that  the  patients 
did  not  complain  of  head  symptoms  sufficient  to  attract 
the  attention  of  the  house  staff. 

Dr.  Dixon  remarked  that  in  his  case  the  man  com- 
plained for  some  months  previous  to  admission  of  only 
chilly  feelings  followed  by  headache,  disappearing  in  the 
evening,  and  recurring  on  the  following  morning,  and 
when  he  entered  the  hospital  he  described  his  headache 
as  being  of  a  burning  character,  and  perhaps  a  little 
more  marked  over  the  frontal  region  than  elsewhere. 

Dr.  John  A.  Wyeth  presented 

A   GOITRE    REMOVED    BY  OPERATION, 

with  the  following  history  :  Theresa  H ,  thirty-six 

years  of  age,  housewife,  a  native  of  Germany,  had  had  a 
goitre  since  she  was  ten  years  of  age,  but  it  never 
troubled  her  until  three  years  ago,  when  it  began  to  in- 
crease in  size,  and  gave  rise  to  difficulty  in  swallowing 
and  breathing.  The  goitre  had  grown  principally  down- 
ward, across,  and  to  the  right,  until  it  involved  the  whole 
anterior  surface  of  the  neck.  She  never  had  exophthal- 
mos or  palpitation  of  the  heart.  During  the  last  three 
years  she  had  had  cough,  which  caused  her  much  pain  in 
the  goitre  and  in  the  head.  There  was  no  family  history 
of  goitre,  and  the  patient's  previous  health  had  been  good. 
On  admission  a  large  goitre  was  seen,  extending  from 
one  side  of  the  neck  to  the  other,  and  extending  be- 
hind either  stemo-mastoid  muscle.  The  narrowest  part 
appeared  in  the  ro<»^««ui  line,  where  it  extended  from  the 


672 


THE   MEDICAL  RECORD. 


[December  13,  1884. 


lower  part  of  the  thyroid  cartilage  to  behind  the  sternum. 
The  lower  border  dipped  down  behind  the  clavicle  and 
sternum.  The  tumor  was  hard,  no  fluctuation,  and  meas- 
ured eight  inches  across,  three  and  a  half  inches  verti- 
cally. There  was  some  visible  pulsation  of  vessels  over 
tumor.  The  patient's  general  condition  was  good.  The 
patient  breathed  with  great  difficulty.  The  laryngoscope 
showed  vocal  cords  close  to  median  line. 

October  23d. — The  patient  has  stridulous,  painful 
cough,  and  breathes  with  much  dyspnoea. 

October  26th. — Operation  under  ether.  Took  the 
anaesthetic  badly.  A  crucial  incision  was  made  over  the 
tumor,  followed  by  careful  dissection.  It  was  found 
necessary  to  extend  the  incision  to  the  left,  dividing  the 
external  and  anterior  jugular  veins  and  the  whole  of  the 
sterno-mastoid  muscle  ;  the  right  sterno-mastoid  muscle 
was  only  partially  cut. 

On  the  left  side  the  internal  jugular  vein  crossed  the 
carotid  artery  to  the  inner  side  and  passed  high  over  the 
side  of  the  tumor  and  was  closely  adherent  to  it ;  it  was 
ligated  above  and  below  the  tumor.  The  trachea  was 
pushed  abruptly  to  ihe  left  by  the  tumor.  About  three- 
fourths  of  an  inch  below  the  larynx,  on  the  posterior 
aspect  ot  the  tumor,  it  was  calcified  and  tightly  adherent 
to  the  trachea.  Very  little  blood  was  lost  during  the 
operation,  which  lasted  four  and  one-half  hours.  It  was 
then  found  impossible  to  separate  the  tumor  from  the 
trachea.  An  elastic  ligature  was  passed  about  the  loosened 
part  of  the  tumor  and  the  wound  left  open.  The  patient 
breathed  badly  throughout  the  operation,  but  her  pulse 
remained  good.  After  the  operation  the  dyspnoea  in- 
creased, and  one  and  one-half  hour  later  the  patient  died, 
apparently  of  oedema  of  the  lungs.  She  was  stimulated 
freely,  and  her  pulse  did  not  fail  until  twenty  minutes 
before  death.  The  tumor  was  removed  post-mortem, 
and  the  part  ligated  off  proved  to  be  less  than  one-half. 
The  lower  and  back  parts  were  hard  and  cartilaginous, 
and  contained  deposits  of  calcific  material  which  looked 
as  if  cysts  had  undergone  calcific  degeneration.  The 
vessels  on  the  right  side  were  not  disturbed,  but  on  the 
left  side  the  carotid  was  exposed  for  four  inches  with  the 
pneumogastric  nerve  by  its  side  uninjured.  The  internal 
jugular  was  ligated  above  and  below  the  tumor.  Nearly 
all  the  vascular  connections  of  the  tumor  had  been 
ligated. 

In  two  other  cases,  already  reported  to  the  Society, 
Dr.  Wyeth  had  removed  the  thyroid  gland  successfully. 

Dr.  Wendt  asked  Dr.  Wyeth  if  in  his  successful  cases 
he  removed  the  thyroid  gland  completely. 

Dr.  Wyeth  replied  that  the  disease  occupied  only  one- 
half  of  the  thyroid  body,  which  was  removed  with  the 
isthmus  up  to  its  junction  on  the  opposite  side. 

Dr.  Wendt  said  the  reason  he  asked  was  because 
Bruns,  of  Tubingen,  had  recently  again  directed  atten- 
tion to  the  fact  that  when  the  thyroid  body  had  been 
completely  removed  the  patient  developed  a  peculiar 
characteristic  cachectic  condition,  and  had  often  died  at 
periods  varying  in  length  from  six  months  to  several  years 
after  the  operation.  This  observer  had  concluded  that 
complete  removal  of  the  thyroid  body  was  therefore  un- 
justifiable, whether  the  gland  was.  diseased  or  not. 

Dr.  Wyeth  remarked  that  he  did  not  wish  to  be  un- 
derstood as  favoring  removal  of  the  thyroid  body  by 
surgical  operation. 

Dr.  Howe  thought  that  the  application  of  so  many 
ligatures  could  be  avoided  by  adopting  a  plan  recom- 
mended by  Bluxom,  of  Charing-Cross  Hospital,  London, 
who  makes  an  incision  in  the  median  line,  divides  the 
tumor  into  two  equal  parts,  then  ligates  one-fourth  of  the 
tumor,  tying  it  on  each  side,  and  cuts  the  mass  included 
in  that  ligature  completely  out  without  special  hemor- 
rhage. He  reports  three  cases  of  recovery  without  the 
development  of  any  peculiar  cachexia. 

Dr.  Wyeth  said  that  in  his  last  case  the  tumor  was 
so  vascular  that  had  he  split  the  tumor  with  a  ligature 
the  woman  would  have  died  of  hemorrhage  at  once. 


^vixm  S^ewB. 


Official  List  of  Changes  in  the  Stations  and  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army^ 
from  November  30  to  December  6,  1 884. 

Irwin,  B.  J.  D.,  Major  and  Surgeon.  Granted  one 
month's  leave  of  absence.  S.  O.  ic 2,  Department  of 
Arizona,  November  28,  1884. 

O'Reilly,  Robert  M.,  Captain  and  Assistant  Sur- 
geon. Assigned  to  duty  as  Attending  Surgeon,  Wash- 
ington City,  D.  C,  to  date  from  October  20,  1884.  S. 
O.  284,  A.  G.  O.,  December  4,  1884. 

Barrows,  C.  C,  First  Lieutenant  and  Assistant  Su^ 
geon.  In  addition  to  other  duties,  to  takp  charge  of 
the  office  of  Medical  Director,  Department  of  Arizona, 
during  absence  of  Surgeon  B.  J.  D.  Irwin.  S.  0.  in, 
Department  of  Arizona,  November  28,  1884. 

Kneedler,  William  L.,  First  Lieutenant  and  As- 
sistant Surgeon.  Relieved  from  duty  at  Fort  A.  Lincoln, 
Dakota  Territory,  and  ordered  to  Camp  Poplar  River, 
Montana  Territory,  S.  O  140,  Department  of  Dakota, 
November  25,  1884. 

Pilcher,  James  E.,  First  Lieutenant  and  Assistant 
Surgeon.  To  be  relieved  from  duty  at  Camp  Poplar 
River,  Montana  Territory,  and  ordered  to  Fort  A.  Lin- 
coln, Dakota  Territory.  S.  O.  140,  Department  of  Da- 
kota, November  25,  1884, 

McCaw,  W.  D.,  First  Lieutenant  and  Assistant  Sur- 
geon. Relieved  from  duty  at  Fort  Wingate,  New  Mexico, 
and  ordered  to  Fort  Lyon,  Colorado.  S.  O.  228,  De- 
partment of  Missouri,  November  26,  1884. 

Gray,  Charles  C,  Major  and  Surgeon.  (Retired) 
Died  at  Geneva,  New  York,  November  26,  1884. 


Contagious  Diseases — Weekly  Statement.— il^ 
port  of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  December  6,  1884 : 


Week  Ending 

£ 

1 

1 

Ss 

1 

1 

j 

1 

1 

Casts. 

November  29, 1884 

December  6,  1884. 

0 
0 

42 

a2 

% 

2 

8 

90 
155 

55 

75 

0 
0 

0 
0 

Dtaiks, 

November  29,  1884 

December  6,  1884 

0  1  15     14      2 

0  1  io|  13      8 

23 
22 

26 
43 

0 
0 

0 
0 

A  French  Cure  for  Corns. — Saturate  the  stockings 
at  the  point  covering  the  corns  in  a  solution  of  phos- 
phorus in  olive  oil  (one  part  to  three  hundred) ;  wear 
them  as  usual,  and  in  fifteen  or  twenty  days,  it  is  claimed, 
the  corns  will  have  disappeared. 

The  Oldest  Physician  in  the  State. — Dr.  Thomp- 
son Burton  writes  us  that  Dr.  Joseph  Braman,  of  Bra- 
man's  Comers,  Schenectady  County,  is  the  oldest  Mason 
(and  probably  the  oldest  physician)  in  the  State.  He 
was  ninety-one  years  old  on  August  30,  1884. 

Hygiene  and  Bacteriology. — A  department  of  hy- 
giene and  bacteriology  has  been  opened  in  connection 
with  the  chemical  laboratory  of  Professor  Fresenias  at 
Wiesbaden.  Dr.  K.  Hueppe,  who  has  done  much  work 
under  Dr.  Koch  at  Berlin,  has  been  appointed  to  the 
charge  of  this  department. 


The   Medical   Record 

A   Weekly  yournal  of  Medicine  and  Surgery 


Vol.  26,  No.  25 


New  York,  December  20,  1884 


Whole  No.  737 


©rigitmt  %xXxt\tz. 


DO  WE  PRODUCE  AVOIDABLE  PAIN  AND 
COMPLICATIONS  IN  THE  DIAGNOSIS  AND 
TREATMENT  OF  STRICTURE  CONSECUTIVE 
TO  GONORRHOEAL  URETHRITIS? 

By  FANEUIL  D.  WEISSE,  M.D., 

PSOFBSSOR  OP  PRACTICAL  AND  SUKGZCAX,  ANATOMY,  MEDICAL  DEPARTMENT  OK  THE 
UNIVERSITY  OP  THE  CITY  OP  NEW  YORK  ;  VISITING  SURGBON,  WORKHOUSE  AND 
ALMSHOUSE  HOSPITAL,  NEW  YORK  OTY. 

The  above  question  is  put  and  discussed  not  in  the  spirit 
of  idle  criticism  or  antagonism  to  orthodox  practice,  but 
with  the  hope  that  both  the  question  and  the  argument 
may  be  weighed  in  the  light  of  individual  experience. 
The  motive  of  the  article  is  to  present  a  strong  convic- 
tion held  that  the  present  use  of  instruments  in  the 
urethra  in  the  diagnosis  and  treatment  of  stricture  con- 
secutive to  gonorrhoeal  urethritis  does  give  needless  im- 
mediate pain,  and  does  produce  avoidable  local  and  con- 
stitutional complications.  It  is  desired  to  suggest  a  basis 
for  the  collection  of  past  experience  and  future  observa- 
tions, which  may  lead  to  the  accumulation  of  positive 
evidence  that  will  modify  our  use  of  instruments  in  the 
urethra  in  these  cases.  Such  modification  will  diminish 
suffering  and  give  more  precision  to  our  instrumental 
procedures  for  the  relief  of  our  patients. 

First. — The  locality  of  stricture  of  the  urethra  consecu- 
tive to  gonorrhoeal  urethritis  does  not  warrant  the  intro- 
duction of  instruments  interiorly  to  the  triangular  liga- 
ment^ or  through  the  membranous  and  prostatic  portions  of 
the  urethra  into  the  bladder. 

All  authorities  are  agreed  that  the  prostatic  portion  of 
the  urethra  is  never  the  seat  of  stricture  from  any  cause. 
The  membranous  portion  is  acknowleged  as  the  locality 
where  traumatic  stricture  most  frequently  occurs.  Special 
statistics  are  wanting  as  to  the  occurrence  of  stritture 
consecutive  to  gonorrhceal  urethritis  in  the  membranous 
portion. 

Writers  upon  the  subject  of  strictu]:e  of  the  urethra 
confirm  the  localization  of  thb  form  of  stricture  exteriorly 
to  the  triangular  ligament,  at  times  by  the  direct  state- 
ment, at  others  by  implication,  but  conclusively  so  in 
the  detailed  recitsd  of  cases,  when  accurate  measure- 
ments are  given.  Dr.  Fessenden  N.  Otis  ("Stricture  of 
the  Male  Urethra,"  p.  134)  defines  stricture  consecu- 
tive to  gonorrhoeal  urethritis,  as  follows :  "  Stricture  in 
the  sense  of  an  abnormal  contraction  of  the  urethral 
calibre,  at  some  point  at  or  between  the  meatus  urinarius 
and  the  bulbo-membranous  junction."  At  this  "junc- 
tion," it  will  be  remembered,  is  the  triangular  ligament. 

The  most  recent  observations  which  have  been  made 
in  locating  stricture  of  the  urethra  from  all  causes  are 
those  of  Otis  and  Gross ;  they  were  made  upon  hving 
patients,  with  the  metal  bougie  a  boule. 

Otis  (op.  cit,  p.  96)  located  258  strictures,  from  all 
causes,  as  follows  :  52  in  first  J  inch  within  the  meatus, 
€^  from  \  to  ij  inches  from  the  meatus,  48  from  i  J  t02i 
inches,  48  from  2^  to  3^  inches^  19  from  3^^  to  4^  inches, 
X4  from  4^  to  5^^  inches,  8  from  5^  to  6\  inches,  6  fi-om 
6^  to  ^\  inches.  The  52  cases  in  the  first  one-quarter 
of  an  inch  within  the  meatus  might  be  discarded  as  con- 
ditions of  congenitally  small  meati. 

Professor  S.  W.  Gross,  M.D.  (**  Diseases  of  the  Uri- 
nary Organs,'*  p.  454)  located  173  strictures,  from  all 


causes,  with  the  following  result:  49,  or  28.32  per  cent., 
were  within  2^  inches  from  the  meatus;  48,  or  27.74  per 
cent,  were  between  2^  inches  from  the  meatus  and  i 
inch  from  the  triangular  ligament ;  76,  or  43.93  per  cent,, 
were  between  i  inch  in  front  and  f  of  an  inch  behind  the 
triangular  ligament. 

Combining  the  two  series  of  observations  (less  Otis*  52 
cases  within  one- fourth  of  an  inch  of  the  meatus)  we  obtain 
the  following  localization  of  379  strictures  of  the  urethra 
in  living  patients,  with  living  histories :  289,  or  76.24  per 
cent,  were  between  i  inch  in  firont  of  the  triangular  liga- 
ment and  the  meatus ;  90,  or  23.75  per  cent,  were  be- 
tween I  inch  in  front  of  and  J  of  an  inch  behind  the 
triangular  ligament  If  the  last  90  cases  had  been  care- 
fully recorded  as  to  their  locale^  so  as  to  determine  posi- 
tively whether  or  not  they  were  exteriorly  to  the  triangular 
ligament,  a  very  large  number  of  them  would  have  been 
located  in  the  one  inch  in  front  of  the  triangular  liga- 
ment. It  would  be  safe  to  say  that  343,  or  90.24  per  cent.,, 
of  the  ^1^  strictures  were  located  exteriorly  to  the  trian^ 
gular  ligament. 

It  is  much  to  be  regretted  that  in  both  Otis'  and 
Gross'  cases  the  causes  of  the  strictures  were  not  given. 
The  weight  of  evidence  from  daily  practice  will  fully 
endorse,  and  even  go  further  than.  Gross  in  his  opinion 
(op.  cit,  p.  452)  :  "  Judging  from  my  own  experience, 
I  am  convinced  that  at  least  90  per  cent,  of  all  cases, 
not  traumatic,  are  the  effect  of  gonorrhoea."  Upon 
this  basis  we  would  not  be  straining  a  point  to  assume 
that  303,  or  90.24  per  cent,  of  the  above  349  strictures 
located  exteriorly  to  the  triangular  ligament  were  consec- 
utive to  gonorrheal  urethritis. 

With  these  data  in  mind,  and  a  case  of  suspected 
stricture  with  a  history  of  antecedent  gonorrhoeal  ure- 
thritis, are  we  warranted  in  passing  an  instrument  in- 
teriorly to  the  triangular  ligament  (or  the  diagnosis  of  the 
same  ?  With  a  stricture  located  by  instrumental  exam- 
ination  exteriorly  to  the  triangular  ligament,  why  should 
an  instrument  be  passed  interiorly  to  the  ligament  ? 

I  hold  that  all  cases  of  stricture  consecutive  to  gonor- 
rhoeal urethritis  are  located  exteriorly  to  the  triangular 
ligament.  When  the  urethritis  passes  interiorly  to  the 
triangular  ligament  it  may  produce  an  epididymitis,  by 
continuous  progress  into  the  ejaculatory  ducts,  etc., 
or  an  attack  of  cystitis  by  progressing  to  the  bladder, 
but  it  does  not  produce  stricture  of  the  membranous 
portion  of  the  urethra. 

Second. — The  instruments  in  general  use  for  the  diag- 
nosis and  treatment  of  stricture  of  the  urethra  consecutive 
to  gonorrheal  urethritis  are  calculated  to  produce  need* 
less  pain  and  avoidable  local  and  constitutional  complica- 
tions. 

The  instruments  in  general  use  m  the  treatment  of 
this  variety  of  stricture  are  sounds  and  bougies ;  while 
the  metal  bougie  k  boule,  urelhrometers,  urethral  divul- 
sors,  urethral  dilators,  and  urethrotomes  are  in  the  hands 
of  specialists  and  a  limited  number  of  general  prac- 
titioners. 

Authors  of  surgical  text-books,  writers,  as  specialists, 
on  male  genito-urinary  diseases,  professors  of  surgery  in 
their  didactic  and  clinical  lectures,  all  concur  in  advising 
the  use  of  sounds  and  bougies  in  the  diagnosis  and  treat- 
ment of  all  cases  of  stricture  of  the  urethra  (making  no 
exception  for  strictures  consecutive  to  gonorrhoeal  ure- 
thritis). They  convey  the  idea,  if  they  do  not  say  so  in  so 
many  words,  and  practise  it  at  their  clinics,  that  a  patient 


674 


THE  MEDICAL   RECORD. 


[December  20, 1884. 


is  not  examined  until  the  sound  or  bougie  has  reached 
the  bladder. 

The  history  of  the  artnamentarium  for  the  diagnosis  and 
treatment  of  stricture  of  the  urethra  bears  evidence  of  a 
departure,  here  and  there,  from  the  use  of  the  time- 
honored  sound  and  bougie.  They  are,  however,  only 
isolated  instances  of  a  conservative  appreciation  of  the 
conditions  to  be  treated,  which  have  not  made  sufficient 
impression  upon  the  general  profession  to  lead  to  their 
adoption  or  to  any  modification  of  the  prevailing  methods 
of  practice. 

After  careful  measurements  of  the  sounds  in  general 
use,  as  made  by  our  leading  instrument  makers  (for  their 
circumference  Dr.  C.  H.  Thomas'  '*  Adaptable  metric 
gauge  "  was  used),  the  following  appears  : 

The  average  length  of  a  sound  is  eight  and  a  half 
inches  from  the  handle  to  the  tip ;  its  straight  portion 
varies  from  six  to  seven  inches,  its  curve  from  one  and 
a  half  to  two  and  a  half  inches ;  the  circumference  of  the 
straight  portion  is  uniform  throughout  and  represents 
the  full  size  of  the  instrument ;  the  circumference  of  the 
curved  portion  diminishes  from  the  end  of  the  straight 
portion  to  the  tip  of  the  instrument,  varying  in  the  diflfer- 
ent  instruments.  In  a  few  exceptional  instances,  the 
special  make  of  the  sound  is  such,  that  the  circumference 
of  the  straight  portion  is  continued  into  the  curve  to 
within  an  inch  of  the  tip. 

From  careful  measurements  of  flexible  bougies  of  all 
kinds,  French  and  English,  they  were  found  as  follows : 
They  vary  in  length  from  ten  and  one-fourth  to  thirteen 
inches ;  the^  have  a  uniform  circumference,  the  full  size 
of  the  bougie,  to  within  three  inches  of  the  tip  ;  for  their 
terminal  three  inches  they  diminish  in  circumference  very 
much,  to  expand  again  in  the  bulbous  and  olive-tipped 
varieties. 

From  the  shape  and  length  of  the  above  instruments, 
as  thus  carefully  determined,  it  will  be  seen  that  the 
curve  of  the  one  and  the  length  of  both  do  not  adapt 
them  for  treatment  of  the  six  inches  of  the  urethral 
canal  exteriorly  to  the  triangular  ligament.  When  di- 
rected to  be  used  it  implies  their  passage  into  the 
bladder. 

The  sensations  of  a  patient  when  one  of  these  instru- 
ments is  passed  into  the  bladder  are  : 

1.  When  a  full-size  sound  or  bougie  is  inserted, 
an  excessively  painful  distention  of  the  meatus,  which  is 
unnecessarily  prolonged,  because  the  circumference  of 
the  sound  or  bougie  increases  from  the  tip. to  the  handle 
end  of  the  instrument ;  and  for  six  inches  of  the  sound 
(straight  portion)  and  at  least-  nine  inches  of  the  bougie 
the  circumference  is  uniform  and  represents  the  full  size 
of  the  instrument. 

2.  Pain  is  always  produced  in  passing  an  instru- 
ment through  the  triangular  ligament ;  and  a  painful 
sense  of  fulness  is  felt  while  the  membranous  portion  of 
the  urethra  is  occupied  by  the  instrument. 

3.  As  the  instrument  passes  through  the  prostatic 
portion  of  the  canal  over  the  sinus  pocularis  or  utric- 
ulus,  containing  the  orifices  of  the  ejaculatory  ducts,  a 
markedly  unpleasant,  reflex,  systemic  impression  is  pro- 
duced, which  is  augmented  by  the  entrance  of  the  instru- 
ment into  the  bladder. 

Professor  Gross  (op.  cit.,  p.  489)  says :  "It  is  well 
known  that  patients,  especially  sudi  as  are  very  ner- 
vous and  irritable,  occasionally  suffer  most  violently 
from  the  most  trifling  operations  upon  the  urinary  organs, 
the  mere  passage  of  a  bougie,  sound,  or  catheter  [pre- 
sumably passed  into  the  bladder]  *  inducing  violent 
rigors,  excessive  prostration,  and  other  symptoms.  In- 
deed, a  large  number  of  cases  are  upon  record  in  which 
death  was  produced  by  this  cause,  even  when  there  was 
no  severe  disease;  and  there  are  few  practitioners  of 
any  experience  in  this  branch  of  surgery  who  have  not 
witnessed  the  distress,  local  and    constitutional,  which 

>  Words  in  brackets  are  added. 


healthy  persons  often  suffer  from  the  attempt  to  pass  an 
instrument  into  the  bladder." 

Another  authority  (Van  Buren  and  Keyes,  "  Genito- 
Urinary  Diseases,"  etc.,  p.  150)  says:  "The  miscWef 
to  be  feared  from  the  employment  of  large  sounds  with 
force  is  the  production  of  epididymitis,  a  common  result 
of  violence  to  the  urethra  [prostatic  portion]/  and  a 
complication,  which  suspends  treatment  and  confines 
the  patient  for  several  days  or,  it  may  be,  weeks."  Fur- 
ther on  the  same  authority  sa^s:  "In  rare  instances 
epididymitis  may  come  on  m  spite  of  care.*' 

Add  to  this  well-known  effect  of  the  use  of  instnuncnts 
passed  into  the  bladder  the  reflection  made  by  the  last- 
named  authorities  upon  epididymitis  (p.  416) :    "Qoe 
particularly  interesting  feature  of  the  disease  is  the  ^ 
mainly  brought  out  of  late  years  by  Gosselin,  that  the 
chronic  induration  so  often  left  behind  in  the  epididynas 
by  inflammation  sometimes  blocks  up  the  tubes  suffid- 
ently  to  prevent  the  passage  of  the  spermatic  elements, 
thus  entailing  temporary  and  sometimes  permanent  ste- 
rility, without  an  accompanying  loss  of  sexual  power." 
Further  on  (p.  422)  occurs  the  following,  in  speakmg  of 
this  sterile  condition  of  the  patient  after  double  epididy- 
mitis :    "  He  ejaculates  semen  resembling  the  healthy 
fluid  in  quantity,  smell,  and  color,  only  it  contains  do 
spermatozoa,  and  consequently  he  is  sterile." 

My  own  experience  furnishes  two  cases  where  I  exam- 
ined the  ejaculated  fluid  of  patients,  who  had  previously 
had  attacks  of  epididymitis  (double),  where  no  spemia- 
tozoa  could  be  found.  In  one  of  the  cases  the  right 
epididymitis  was  consecutive  to  the  gonorrhoeal  urethri- 
tis, while  the  left  epididymitis  was  the  result  of  the  use  of 
instruments  (sounds)  passed  into  the  bladder  for  the 
treatment  of  a  stricture  consecutive  to  the  gonorrhoeal 
urethritis;  the  stricture  was  located  exteriorly  to  the 
triangular  ligament — 3^  inches  from  the  meatus. 

Why  incur  all  the  above  risks  by  passing  instniments 
interiorly  to  the  triangular  ligament  when  the  nature  of 
the  case  does  not  call  for  it? 

I  hold  that  all  instruments  designed  to  be  passed  into 
the  bladder  are  not  to  be  used  in  the  diagnosis  and 
treatment  of  stricture  of  the  urethra  consecutive  to  gon- 
orrhoeal urethritis,  for  the  reason  that  I  believe  their  pas- 
sage interiorly  to  the  triangular  ligament  is  what  pro- 
duces all  the  above  *'  local  and  constitutional  distress." 

For  the  past  three  years  I  have  not  passed  an  instni- 
ment  interiorly  to  the  triangular  ligament  for  the  diag- 
nosis* or  treatment  of  this  variety  of  stricture.  I  be- 
lieve the  reason  that  I  have  not  had  any  ''  local  and 
constitutional  distress,''  from  the  use  of  instruments  for 
diagnosis  and  dilatation  of  this  form  of  stricture,  has 
been  because  my  instrumental  procedures  were  limited 
to  the  urethral  canal  exteriorly  to  the  triangular  ligament 

Third. — All  instruments  used  in  the  diagnosis  and 
treatment  of  stricture  of  the  urethra  consecutive  to  gonor- 
rhoeal urethritis  should  be  so  made  as  to  meet  the  foUow- 
ing  requirements :  simplicity  of  construction^  compatihk 
with  the  needs  to  be  fulfilled ;  length  such  that  they  can- 
not be  passed  interiorly  to  the  triangular  ligament;  a  va- 
riation of  circumference  such  as  to  give  the  least  possible 
continuance  of  pain  from  distention  of  the  meatus  ;  ruled 
so  as  to  locate^  measure^  and  treat  with  immediate  prt- 
cision  the  stricture  or  strictures  present, 

I  would  present  to  the  profession  the  following  per- 
fected instruments,  made  for  me  by  Stohlmann,  Pfarre  k 
Co.,  which  have  been  devised  to  fulfil  the  above  requi^^ 
ments  of  instruments  for  the  diagnosis  and  treatment  (by 
dilatation)  of  stricture  of  the  urethra  consecutive  to  gonor- 
rhoeal urethritis. 

A  set  of  metal  bougies  d  boule  with  non-flexible^  ndei 
staffs  (Fig.  i). — These  are  Otis'  metal  bougie  a  boule 
with  a  non-flexible,  ruled  staff,  and  with  a  bulb  at  either 
end — giving  two  sizes  to  the  one  instrument  Its  length 
is  adapted  for  examination  of  the  urethral  canal  exteriorly 

>  Words  in  brackets  added. 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


675 


to  the  triangular  ligament — it  is  six  and  one-quarter  inches 
from  the  apex  of  one  bulb  to  the  base  of  the  other.  The 
bulbs  are  scaled  from  14  to  37  of  the  French  scale.  The 
staffs  smaller  than  the  bulbs,  has  two  flattened  sides, 
which  are  ruled  in  one-quarter  of  an  inch  spaces,  so  that 
as  an  obstruction  is  met  with  the  distance  of  its  exterior 
face  from  the  meatus  can  be  read  off.  Then  selecting  one 
of  the  bougies,  the  bulb  of  which  will  go 
through  the  strictured  point  tightly,  pass 
it  beyond  the  stricture,  and  on  attempt- 
ing to  withdraw  the  same  the  base  of 
the  bulb  will  be  arrested  at  the  interior 
face  of  the  stricture,  when  the  distance 
of  the  latter  from  the  meatus  may  in 
turn  be  read  off.  The  difference  of  the 
distances  from  the  meatus  to  the  ex- 
terior and  interior  faces  of  the  stricture 
will  be  the  length  of  the  strictured  por- 
tion. 

A  set  of  urethral  sounds  with  ruled 
staffs  (Fig.  2). — These  instruments  have 
a  sound  portion  at  either  end — two  sizes 
to  one  instrument — and  an  intervening 
staff  portion.  A  sound  portion  is  two 
inches  in  length ;  the  middle,  for  an  inch, 
presents  the  full  circumference  or  size 
of  the  sound  in  millimetres  (French 
scale) ;  the  ends  (for  half  an  inch  each) 
taper  through  several  sizes.  The  staff^ 
portion  has  much  less  circumference 
than  the  sound  portions,  and  it  is  four 
and  a  quarter  inches  in  length ;  it  is 
flattened  on  two  sides  (one  for  each 
of  the  end  sounds),  which  are  ruled  in 
inches,  with  the  quarter-inch  divisions). 
The  length  of  instrument  introduced 
into  the  urethra  is  six  and  one-quarter  inches  from  the 
tip  of  one  sound  portion  to  the  base  of  the  other. 

A  given  stricture  located  by  the  bougies  k  boule,  the 
proper  sized  urethral  sound  is  selected  and  passed,  by  the 
ruling  on  the  stafl*,  so  as  to  bring  the  centre  of  the  sound 
portion  exactly  at  the  strictured  portion  of  the  canal. 

In  using  these  instruments,  the  length  of  the  urethral 
canal  exteriorly  to  the  triangular  ligament  will  be  found 
to  vary  from  four  and  three-quarters  to  six  and  one- 
quarter  inches.  A  little  experience  will  enable  one  to 
recognize  when  the  triangular  ligament  is  reached,  as  it 
imparts  to  the  finger,  when  tapping  the  end  of  the  bougie 
k  boule  or  urethral  sound  protrudmg  from  the  meatus,  a 
peculiar  sensation  of  elasticity,  not  given  by  the  exterior 
face  of  a  stricture. 

In  closing  I  would  suggest : 

First, — ^That,  in  locating  a  stricture  of  the  urethra,  we 
determine  as  to  whether  it  is  exteriorly  or  interiorly  to 
the  triangular  ligament. 

Second, — That,  in  describing  a  case  of  stricture  of  the 
urethra,  we  discard  all  terms  heretofore  used  in  locating 
the  same,  and  specifically  state  its  relation  to  the  triangu- 
lar ligament  exteriorly  or  interiorly.  The  exact  distance 
of  the  same  from  the  meatus  should  be  stated. 

Third, — That  all  members  of  the  profession  contributfe 
their  experience  toward  the  accumulation  of  statistics, 
which  may  definitely  settle  the  location  of  stricture  of  the 
urethra  consecutive  to  gonorrhoea!  urethritis. 


Fic* 


Fic'a. 


Dropping  Fluids  into  the  Eye.^  The  inner  corner 
of  the  eye  is  first  cleaned  from  all  impurities,  and  then 
thoroughly  dried.  While  the  child  is  in  the  recumbent 
position,  the  eye  is  kept  closed.  One  or  two  drops  of 
the  fluid  indicated  in  the  case  are  then  dropped  into  the 
comer.  When  the  child  opens  the  lid,  the  drops  flow 
slowly  into  the  eye.  Should  the  child  be  asleep,  or  not 
at  once  open  the  eye,  the  operator  needs  but  slightly  to 
separate  the  eyelids,  when  the  drops  will  immediately  en- 
ter.— Medical  and  Surgical  Reporter. 


ON  THE  NECESSITY  OF  PROVIDING  FOR 
THE  BETTER  EDUCATION  OF  CHILDREN 
WITH  DEFECTIVE  HEARING  IN  THE  PUB- 
LIC SCHOOLS. » 

By  SAMUEL  SEXTON,  M.D., 

AURAL  SUKCBON  TO  THB  NEW  YORK  SYS  AND  EAR  INnRMARY. 

The  purpose  of  this  paper  is  to  enlist  an  interest  in  our 
public  school  systems  in  so  far  as  concerns  the  needs  of 
pupils  whose  hearing  disabilities  prevent  their  advance- 
ment along  with  good  hearing  scholars,  since  it  is  be- 
lieved that  this  matter  does  not  receive  the  attention  its 
importance  demands. 

The  varieties  of  deafness, — ^The  defective  children  be- 
lieved to  be  greatly  neglected  in  regard  to  their  education 
may,  for  convenience  in  this  connection,  be  arranged  into 
three  classes,  namely : 

1.  Children  defective  in  one  or  both  ears,  and  requir- 
ing close  proximity  and  distinct  utterance  when  taught. 
Of  these,  deafness  in  both  ears  requires  seating  on  front 
row  of  benches,  but  when  only  one  ear  is  affected  the 
normal  ear  must  be  toward  the  teacher's  desk. 

2.  Children  very  deaf,  who  cannot  distinguish  ordinary 
conversation  in  either  ear  when  more  than  a  few  inches 
from  the  speaker  or  unless  the  conversation  tube,  ot- 
acoustic  fan,  or  other  aid  to  hearing  be  employed. 

3.  The  totally  deaf,  in  whom  the  auditory  apparatus  of 
the  middle  ear  cannot  be  made  available.  This  class 
admits  of  division  into  two  subdivisions,  viz.:  «,  thbse 
having  learned  to  talk  previous  to  losing  their  hearing, 
and  ^,  those  bom  too  deaf  to  ever  have  naturally  ac- 
quired speech,  commonly  known  as  congenital  deaf- 
mutes. 

Deafness  in  the  schools  from  a  physician's  point  of 
view, — In  considering  the  relations  of  all  classes  of  deaf 
pupils  with  both  the  public  day-schools  and  deaf-mute 
schools  from  the  physician's  point  of  view,  it  is  believed 
that  the  extent  and  importance  of  the  subject  may  be 
more  fully  realized  than  in  any  other  way,  since  where 
professional  advice  is  required  opportunity  is  allowed  for 
thorough  examination  of  the  hearing  organs,  both  as  re- 
gards their  physical  condition  and  acoustic  functions. 
A  very  considerable  experience,  including  observations 
on  a  large  number  of  specially  interesting  cases  among 
school  children  of  the  poorer  class,  seen  in  hospital  prac- 
tice, led  the  writer  to  believe  that  great  injustice  was  be- 
ing done  in  permitting  children  to  struggle  for  an  educa- 
tion under  the  disadvantages  arising  from  deafness  with- 
out the  aid  of  methods  which  experience  had  shown  to 
be  advantageous  in  such  cases ;  he  therefore  concluded 
to  make  some  efforts  in  their  behalf,  and  in  1877  the 
matter  was  brought  to  the  notice  of  the  Board  of  Educa- 
tion of  New  York. 

Its  consideration  by  the  New  York  Board  of  Education 
in  1877. — The  Board  referred  the  matter  to  the  Com- 
mittee on  Teachers,  and  in  explaining  the  matter  to  them 
it  was  shown  that  some  children  contmued  on  at  school, 
for  years  even,  while  scarcely  any  hearing  remained, 
while  there  were  many  others  who  heard  very  badly  ;  that 
in  disregarding  this  matter  deaf  children  were  placed  at  a 
serious  disadvantage,  and  that  the  time  wasted  in  futile 
attempts  to  instruct  them  was  a  hindrance  to  others. 
Instances  of  special  injustice  were  cited  where  (children, 
defective  in  hearing,  had  made  great  efforts  both  at 
school  and  at  home  to  prepare  themselves  for  promotion, 
only  to  be  put  back  on  examination,  because  the  princi- 
pal was  not  aware  of  the  child's  imperfection,  and  there- 
fore had  not  given  his  questions  distinctly  enough  to  be 
heard.  Other  deaf  children,  from  neglect  to  classify 
them,  were  seated  too  far  away  from  the  teacher's  desk 
to  hear  his  voice,  and  in  consequence  of  inability  to  reply 
correctly  were  frequently  punished  for  inattention  and 
dulness.    The  rudeness  often  practised  toward  these  un- 

>  A  paper  read  before  the  Hospital  Committee  of  the  State  Charities  Aid  As- 
sociation, New  York,  December  3,  2884. 


676 


THE  MEDICAL  RECORD. 


[December  20, 1884. 


fortunate  pupils  by  unthinking  or  unsympathetic  teachers 
was  discouraging,  and  some  pupils  in  consequence  had 
left  school  altogether. 

It  was  not  recommended  at  this  time  that  the  partially 
deaf  should  be  entirely  separated  from  the  hearing  pupils, 
yet  it  was  advised  that  pupils  should  always  be  examined 
in  regard  to  their  hearing,  and  that  those  found  to  be  de- 
fective should  be  given  every  possible  advantage,  both  in 
respect  to  seating  and  to  distinctness  of  voice  in  teaching, 
the  very  deaf  should  have  some  instruction  apart  from 
others,  since  they  often  could  not  understand  words 
shouted  into  their  ears.  The  writer  did  not  expect  that 
the  long-established  order  of  things  could  be  rapidly 
changed,  but  it  is  believed  that  teachers  have  become 
more  interested  in  the  subject  than  ever  before,  and  that 
instances  of  "  inattention "  and  "  stupidity "  are  less 
puzzling  since  their  true  character  is  recognized.  Com- 
plaints are  now  less  frequently  made  by  pupils  who  come 
for  treatment  of  neglect  in  this  regard,  and,  indeed, 
teachers  very  often  recommend  that  deaf  children  be 
brought  to  our  clinics  for  relief. 

Its  consideration  by  the  New  York  Board  of  Educa- 
tion in  1884. — During  the  past  few  months  the  Board  of 
Education  has  again  taken  this  matter  into  consideration, 
a  communication  on  the  subject  from  the  writer  having 
been  referred  to  the  Committee  on  "Course  of  Studies." 
The  Committee  met  on  November  12th,  and  on  invita- 
tion the  writer  presented  some  typical  cases  of  aural 
disabilities  in  children,  and  gave  the  results  of  his  experi- 
ence concerning  deafness  in  the  schools.  The  Commit- 
tee have  not,  as  yet,  so  far  as  I  know,  made  any  recom- 
mendations to  the  Board,  but  it  is  to  be  hoped  that  some 
steps  will  be  taken  in  the  matter  soon. 

Its  consideration  by  the  United  States  Government  in 
188 1. — In  the  meantime  the  subject  of  deafness  among 
school  children  has  attracted  the  attention  of  the  Educa- 
tional Department  of  the  United  States  Government,  and 
the  matter  bein^  considered  important  enough  to  justify 
a  special  investigation  of  its  causes,  the' wnter  was  re- 
quested to  prepare  a  paper  on  the  subject,  which  was 
printed  by  the  Bureau  of  Education  for  distribution  in 
188 1.  An  examination  of  five  hundred  and  seventy-five 
pupils  made  at  that  time  showed  that  there  were  numer- 
ous instances  of  deafness  where  neither  teacher  nor  pupil 
were  aware  of  its  existence,  and  that  fully  thirteen  per 
cent  of  the  whole  number  examined  had  greater  or  less 
diminished  hearing  in  one  or  both  ears.  Of  these,  only 
three  per  cent,  were  themselves  aware  of  any  defect 
existing,  and  only  one  of  them  was  known  to  be  deaf  by 
th*?  teachers. 

Advantages  of  the  study  of  deafness  from  a  clinical 
point  of  view, — A  consideration  of  the  subject  of  aural 
disabilities  should  not  be  confined  to  observations  on 
children  in  the  schoolroom,  where  the  detection  of  deaf- 
ness in  many  cases  must  be  attended  with  difficulties, 
but  investigations  should  also  be  made  at  leisure  with 
favorable  surroundings  and  apparatus  for  obtaining  pre- 
cise results.  Hence  the  more  valuable  conclusions  are 
to  be  drawn  from  examinations  in  practice,  ample  oppor- 
tunities for  which  may  be  found  in  private  and  hospital 
experience.  Thus  from  the  clinical  standpoint  it  may 
be  premised  that  a  large  number  of  persons  come 
through  the  ordeal  of  children's  maladies  and  other 
ailments  affecting  the  ears  either  directly  or  remotely 
with  impaired  hearing  organs.  In  some  the  hardness  of 
hearing  is  very  manifest,  in  others  it  is  unrecognized, 
even  when  considerable.  Some  apathetic  persons  disre- 
gard deafness,  while  the  more  sensitive  endeavor  to 
conceal  their  misfortune. 

Estimate  of  the  extent  of  aural  disabilities  in  the 
United  States. — Careful  estimates  have  been  made,  indi- 
cating that  no  greater  number  than  five  per  cent,  of  the 
entire  population  have  normal  hearing,  bat  this  of  course 
does  not  show  the  number  of  persons  defective  enough 
to  exclude  them  from  the  benefits  of  the  ordinary  com- 
mon-school curriculum.      The   tenth  census  computes 


that  there  are  about  thirty-four  thousand  deaf-mutes  in 
the  United  States,  or  i  out  of  every  1,500.  One  half 
of  these  are  illiterate. 

Estimate  of  the  extent  of  aural  disabilities  in  th 
schools  of  New  York  City, — Nearly  four  thousand  deaf- 
mutes  reside  in  the  State  of  New  York,  and  over  one 
thousand  in  this  city.  Of  the  latter,  575  are  in  asylums. 
The  number  of  totally  deaf  persons  of  the  school  age  in 
this  city,  but  outside  of  asylums,  is  stated  to  be  163;  but 
this  estimate  is  much  too  low,  since  the  enumeration  of 
the ;  census-takers  is  very  unreliable  in  respect  to  this 
class.  Parents  are  slow  to  acknowledge  their  deaf-mute 
progeny,  and  often  the  census-takers  make  no  efforts  to 
get  at  the  facts.  The  writer  has  met  with  a  considerable 
number  of  these  children  who  were  not  enumerated,  and 
he  doubts  not  that  there  are  no  less  than  500  of  them  in 
this  city,  of  the  school  age,  unprovided  with  educational 
facilities. 

Before  the  census  of  1880  was  taken,  the  question  o( 
ascertaining  the  number  of  very  deaf  people  was  consid- 
ered  by  the  special  agent,  Mr.  Wines,  but  the  scheme 
was  abandoned,  as  it  was  thought  that  any  returns  of  this 
kind  would  be  wholly  unreliable  unless  obtained  by  the 
aid  of  expert  examiners.  It  is,  therefore,  impossible  to 
give  a  very  close  estimate  of  their  number ;  but  if  one 
may  form  an  opinion  from  experiences  in  practice,  the 
number  having  more  or  less  disqualifying  aural  defects 
may  be  put  down  at  no  less  than  ten  per  cent,  of  the 
entire  school  population  of  New  York  City.  Thus  out 
of  about  one  hundred  and  forty  thousand  pupils  in  at- 
tendance at  the  public  schools  at  the  present  time,  some 
fourteen  thousand  of  them  would  be  the  better  for  classifi- 
cation  in  respect  to  seating  and  instruction  at  close  range, 
or  by  means  of  some  aid  to  hearing.  These  figures  show 
that  we  have  to  deal  with  a  vast  number  of  defectives,  in 
respect  to  hearing,  and  although  this  avenue  to  illiteracy, 
and  consequently  to  pauperism,  was  not  of  much  signifi- 
cance when  the  country  was  new,  it  surely  demands  our  at- 
tention now,  when  vagrancy  and  kindred  evils  are  attract- 
ing so  much  attention  from  the  vastness  of  their  propor- 
tions. 

The  education  of  the  very  deaf  and  deaf-mutes  in 
the  day-schools. — While  attention  has  thus  been  drawn 
to  the  wants  of  the  partially  deaf,  strenuous  efforts  have 
been  made  in  behalf  of  the  dea£-mute  with  a  view  to  im- 
proving his  educational  facilities.  The  labors  of  Professor 
Alexander  Graham  Bell  in  this  field  have  been  notable, 
and  besides  ^ving  much  personal  attention  to  the  work, 
his  contributions  to  the  literature  of  the  subject  have 
been  numerous  and  valuable.  But  while  the  writer  him- 
self has  mainly  had  in  view  the  needs  of  the  partially 
deaf,  yet  in  pursuing  this  interesting  subject  from  his  own 
point  of  view,  it  is  to  be  plainly  seen  that  from  a  peda- 
gogical standpoint  a  very  considerable  number  of  deaf- 
mutes,  so-called,  may  be  more  advantageously  provided 
for  in  the  public  day-schools  than  otherwise. 

Day-schools  for  deaf-mutes  have  thus  been  established 
in  the  United  States  as  follows:  Horace  Mann  Day- 
school,  Boston,  in  1869  ;  Erie  Day- school,  in  1874;  Chi- 
cago Day-school,  in  1875  ;  Cincinnati  Day-school,  in 
1875  ;  Portland,  Me.,  Day-school,  in  1876;  Rhode  Isl- 
and Day-school,  in  1877;  St.  Louis  Day-school,  in 
1878  ;  Oral  Branch  Pennsylvania  Institution,  Phila- 
delphia, in  188 1 ;  Scranton  Oral  School,  in  1883; 
Phonological  School,  Milwaukee,  in  1878  ;  A.  Graham 
Beirs  School,  Washington,  D.  C,  1883.  ^^  would  seem 
that  the  systems  of  deaf-mute  education  were  under- 
going a  transformation  at  the  present  time,  since  hear- 
ing defects  are  beginning  to  be  regarded  as  consti- 
tuting a  factor  of  varying  importance,  no  longer  ofifering 
an  insurmountable  barrier,  in  a  great  number  of  instances^ 
to  an  education  which  shall  enable  them  to  hold  con- 
verse after  the  manner  of  hearing  persons. 

This  leads  us  to  express  the  opinion  that  very  consid- 
erable numbers  who  are  at  present  being  educated  as 
deaf-mutes  could  be  cared  for  in  the  public  day-schools 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


677 


along  with  the  very  deaf  who  are  at  present  unprovided 
for,  since  they  boUi  require  similar  methods  of  instruc- 
tion. 

Totally  and  very  deaf  children,  moreover,  require  tak- 
ing in  hand  at  a  much  earlier  age  than  is  feasible  in  deaf 
and  dumb  institutions;  their  education  should,  in  fact, 
begin  much  earlier  than  it  is  commenced  at  present ;  they 
should  be  placed  in  school  when  four  or  five  years  old. 
Children  who  have  lost  their  hearing  soon  after  acquiring 
speech  soon  forget  to  talk  unless  means  are  promptly 
taken  to  keep  them  in  practice.  The  same  rule  would 
apply  with  equal  force  to  the  congenitally  deaf,  since 
valuable  time  is  lost  when  instruction  is  neglected  during 
the  impressible  period  of  early  childhood.  It  becomes  a 
necessity  in  respect  to  the  education  of  children  at  such  a 
tender  age  that  they  should  be  provided  for  in  schools 
near  their  homes,  an  entirely  practicable  matter,  fortu- 
nately, in  large  cities  and  towns,  and  even  in  sparsely 
populated  districts,  according  to  the  reasoning  of  Bell  in 
his  "  Memoir  upon  the  Formation  of  a  Deaf  Variety  of 
the  Human  Race." 

As  to  disassociating  very  young  children  from  home 
influences,  the  humane  impulses  of  parents  are  altogether 
opposed  to  this  ;  the  writer  has  often  witnessed  the  dis- 
may and  grief  of  parents  when  informed  that  their  deaf 
children  could  obtain  an  education  only  in  a  deaf  and 
dumb  institution.  There  are,  perhaps,  a  few  families 
who  prefer  to  place  their  children  away  from  home,  where 
the  responsibilities  of  support  and  training  will  be  as- 
sumed by  others,  but  it  is  otherwise  with  our  better  citi- 
zens, who  desire  to  have  them  brought  up  more  as  other 
children. 

.    The  education  of  the  deaf  in  deaf-mute  institutions. 
—In  certain  institutions  an  increased  interest  has  shown 
itself  of  late  ih  respect  to  the  very  considerable  number 
of  pupils  who  have  heretofore  been  treated  as  totally 
deaf,  but  who  are,  in  point  of  fact,  conscious  of  more  or 
less  perception  of  sound,  which  may  be  made  available  in 
education.    The  results  alleged  to  have  been  attained  by 
means  of  aural  teaching  are  very  gratifying.     During  the 
year  1877  the  writer  visited  some  deaf-mute  institutions 
with  a  view  to  discover  what  number  of  these  pupils 
could  hear  the  voice  by  means  of  a  conversation-tube 
placed  in  the  mouth  or  ear,  and  he  was  surprised  to  find 
a  number  being  educated  as  deaf-mutes  with  whom  con- 
versation could  be  carried  on  orally  by  the  employment 
of  this  aid   to   hearing.     Repeated  observations  subse- 
quently made  by  teachers  have  confirmed  the  above,  and 
it  is  now  believed  that  of  all  the  pupils  in  deaf  and  dumb 
institutions  a  large  number  could  be  educated  through 
the  hearing  sense  by  the  aid  of  speaking-tubes  and  ota- 
coustic  fans,  and  that  a  small  number  hear  well  enough 
to  be  taught  by  the  unaided  voice.     In  the  Minnesota 
institution  it  has  been  found  that  from  fifteen  to  twenty- 
five  per  cent,  of  all  the  pupils  received  can  be  taught  by 
the  aural  method,  and  that  after  being  instructed  for  a 
time  many  could  hear  well  enough  at  the  distance  of  ten 
or  fifteen  feet  to  converse  when  elevated  voice  was  used. 
The  confusion  and  consequent  injustice  to  deaf  pupils 
arising  from  neglect  to  classify  them  property. — It  will 
be  admitted,  if  the  figures  above  given  concerning  the 
deaf  be  approximately  correct  even,  and  it  is  believed 
that  as  further  examinations  are  made  they  will  be  found 
not  to  be  in  excess  of  the  correct  number,  that  in  so  far 
as  educational  objects  are  concerned  we  cannot  separate 
pupils  into  two  great  classes,  one  of  which  can  hear  well 
and  the  other  not  at  all,  by  an  arbitrary  or  sudden  line  of 
demarcation,  inasmuch  as  the  hearing  disabilities  of  chil- 
dren consist  in  all  degrees  of  deafness,  ranging  between 
slight  defects  and  absolute  incapacity. 

It  would  seem  necessary,  therefore,  that  some  prac- 
tical scheme  for  the  classification  of  the  deaf  should  be 
made  which  would  not  exclude  any  from  the  schools. 
Under  the  present  arrangement  the  only  class  of  defec- 
tives provided  for  has  been  the  so-called  deaf-mute  class, 
which  leaves  out  of  consideration  entirely  a  laige  num- 


ber of  partially  and  very  deaf  pupils,  occupying,  so  to 
speak,  intermediate  ground  between  totally  deaf  and 
normal  hearing  persons.  This  arrangement  absolutely 
places  a  certain  number  of  pupils  in  a  worse  condition 
than  if  entirely  deprived  of  their  hearing  sense,  and  in 
consequence  a  great  many  of  them  find  their  way  into 
deaf-mute  schools.  Thus  it  will  be  seen  that  the  classi- 
fication in  both  the  day  and  deaf  mute  schools  is  defec- 
tive, and  that  in  any  attempt  to  improve  matters  we  are 
at  once  met  by  a  most  perplexing  dilemma ;  thus,  owing 
to  the  long-continued  practice  of  forcing  all  deaf  pupils 
into  either  a  totally  deaf  or  good  hearing  class,  we  find 
that  some  of  the  former  and  all  of  the  very  deaf  and  par- 
tially deaf  have  been  relegated  to  the  hearing  schools, 
while  other  very  deaf  persons  are  classified  with  the 
totally  deaf  and  taught  as  deaf-mutes. 

The  disadvantages  arising  in  deaf-mute  institutions 
from  the  want  of  classification  show  themselves  in  many 
ways;  thus,  where  no  useful  perception  of  sound  has 
ever  been  experienced  by  a  pupil,  as  in  most  congenitally 
deaf  persons,  there  is  probably  an  entire  inaptitude  for 
the  development  of  the  perceptive  function,  and  while 
efiforts  to  arouse  this  dormant  function  must  not  be  too 
early  abandoned  in  doubtful  cases,  yet  it  is  well  to  con- 
sider how  much  labor  can  be  profitably  devoted  to  the 
task  of  teaching  such  pupils  to  converse  orally.  The 
discouraging  results  in  such  cases  has  doubtlessly  been 
the  means  of  establishing  a  preference  for  teaching  the 
sign  language,  since  in  overcrowded  deaf-mute  institu- 
tions this  method  has  the  advantage  of  being  inexpensive 
— ^an  important  item  where  the  corps  of  instructors  is 
small.  It  has  been  estimated  that  about  ten  per  cent.* 
of  deaf-mute  pupils  belonging  to  this  class  cannot  learn 
to  speak  intelligibly  unless  much  more  attention  is  given 
to  their  instruction  than  is  practicable  in  any  public 
school. 

The  mediocrity  of  results  attained  is  further  increased 
by  the  mental  inertness  of  deaf-mute  pupils  either  ad- 
mitted when  too  old  to  adapt  themselves  successfully  to 
study  or  retained  too  long  after  reaching  adolescence. 

The  duty  of  the  State  in  respect  to  the  education  of  the 
deaf — The  opponents  of  the  proposed  reform  for  teaching 
these  defectives  in  the  public  day-schools  assert  that  the 
policy  of  the  State  is  to  exclude  all  who  cannot  be  re- 
garded as  having  average  mental  and  physical  qualifica- 
tions ;  but  no  one  has  ventmred  to  define  this  standard. 
Indeed,  it  would  be  difficult  to  do  so  ;  and  were  all  of  the 
average  pupils  selected,  what  should  be  done  with  the 
remaining  pupils  ?  This  question  has  thus  far  been  only 
tentatively  met  by  the  attempt  to  separate  all  pupils  into 
good  hearing  and  totally  deaf  classes.^ 

By  many  it  is  held  that  our  public-school  system  has 
for  its  principal  object  the  prevention  of  illiteracy  among 
the  poor,  and  if  this  view  be  correct  it  can  scarcely  be 
regarded  as  consistent  on  the  part  of  the  advocates  of 
educating  the  average  child  only  to  oppose  a  scheme  for 
the  promotion  of  the  interests  of  a  needy  but  uninflu- 
ential  class,  while  fostering  expensive  institutions  for  the 
free  education  of  the  better-to-do,  and  going  so  far  even 
as  to  expend  large  sums  of  money  in  giving  special  in- 
struction in  German,  French,  Music,  etc. 

This  was  certainly  never  contemplated  by  those  who 
founded  the  common-school  system.  Nor  is  it  humane 
to  leave  the  care  of  this  defective  class  to  the  uncertain- 
ties of  philanthropic  aid.  The  State  already  has  abun- 
dant  facilities  for  the  care  of  all  the  deaf-mutes  who  can- 
not be  educated  in  connection  with  the  day  system  of 
public  schools,  and  inasmuch  as  these  institutions  will 
soon  be  overcrowded  by  the  natural  increase  of  this  class, 
it  would  seem  that  facilities  should  be  provided  for 
them  in  the  day-schools  without  delay.  There  are, 
already  17,000  deaf  and  dumb  persons  of  the  school  age 
in  the  United  States,  according  to  the  census  of  1880, 
only  5,000  of  whom  were  in  institutions.  As  has  been 
stated,  there  are  already  in  operation  in  various  sections 
of  the  country  eleven  day-schools  for  the  deaf,  nine  of 


678 


THE  MEDICAL  RECORD. 


[December  20, 1884. 


which,  at  least,  are  under  control  of  the  the  local  boards, 
and  a  bill  is  now  before  the  Wisconsin  legislature  to  au- 
thorize Boards  of  Education  to  take  charge  of  deaf- 
mutes  and  place  them  in  the  day-schools. 

The  expense  of  educating  the  deaf  in  day-schools  as 
compared  with  their  education  in  institutions, — The 
question  of  reform  in  the  education  of  the  defective  in 
hearing  is  to  a  certain  extent  a  question  of  expense ;  that 
they  must  receive  educational  facilities  will  not  be  denied. 

Let  us  consider  the  result  in  this  regard  of  transferring 
to  the  day-schools  what  may  be  regarded  as  their  legiti- 
mate share  of  work.  The  outlay  by  the  State  would 
probably  be  lessened,  so  far  as  the  deaf-mutes  are  con- 
cerned, and,  on  the  other  hand,  it  would  be  slightly  in- 
creased were  proper  methods  introduced  for  the  instruc- 
tion of  the  very  deaf  and  partially  deaf. 

At  the  present  time  it  costs  the  State  to  support  and 
instruct  deaf-mutes  in  its  seven  asylums  $250  per  capita 
annually.  It  will  thus  be  seen  that  were  classes  of  ten 
formed  in  the  public  schools,  which  is  a  smaller  number, 
I  believe,  than  in  asylum  classes,  and  a  teacher  secured 
at  the  rate  of  $800  per  annum,  there  would  be  a  saving 
of  $170  per  pupil  Where  smaller  classes  of  children 
were  formed,  as  might  be  done  in  the  country,  the  savins 
would  be  less.  I  have  no  exact  figures  upon  which  an  esti- 
mate of  the  number  of  partially  deaf  can  be  based.  I  know 
of  but  one  extensive  examination  in  this  direction,  besides 
my  own  ;  this  was  made  by  Weil,  of  Stuttgart,  and  pub- 
lished in  the  Archives  of  Otology  iot  1882.  It  embraced 
the  results  of  an  examination  of  the  ears  and  the  hearing 
of  school  children  of  different  social  grades.  In  some 
schools  the  percentage  of  those  who  heard  badly  was 
as  high  as  30  per  cent  My  own  examinations,  em- 
bracing 570  pupils,  were  made  in  the  intermediate  and 
primary  grades  and  included  some  in  the  Roman  Catholic 
Parochial  and  in  the  Colored  Schools  of  this  city.  It  has 
already  been  stated  that  about  thirteen  per  cent,  of  these 
had  greatly  diminished  hearing,  but  it  would  be  impossible  to 
estimate  the  number  whose  hearing  required  teaching  by 
special  methods  without  a  careful  and  extensive  examina- 
tion being  made.  From  the  large  number  met  with  in 
practice,  however,  I  believe  the  number  to  be  consider- 
able. These,  however,  could  be  taught  in  classes  of 
twenty,  and  the  increased  expense  would  not  be  great ; 
such  pupils  are  at  present  taught,  if  they  attend  school, 
in  classes  with  hearing  children,  and  the  increased  ex- 
pense in  reducing  the  size  of  classes  to  accommodate 
them  may  be  easily  computed. 

There  need  be  no  expense  for  new  buildings,  the 
structures  at  present  in  use  for  school  purposes  being 
sufficient,  since  it  is  thought  best  not  to  separate  one 
class  from  another  entirely  any  more  than  the  different 
grades  are  now  taught  apart  Some  instruction  would  be 
common  to  all. 

Teachers  of  deaf  pupils, — Many  teachers  have  already 
fitted  themselves  for  this  work,  and  it  is  a  significant  fact 
that  the  growing  demand  for  better  instruction  of  the 
deaf  has  enabled  them  to  find  ready  employment  either 
in  families  or  in  conducting  small  private  day-schools, 
since  parents  are  willing  to  incur  this  extra  expense 
rather  than  place  their  children  in  deaf-mute  institutions. 
Where  this  expense  cannot  be  borne,  and  parents  are  un- 
wilhng  to  send  their  children  away  from  home,  it  seems 
that  to  exclude  them  from  the  advantages  of  day-schools 
is  to  disregard  their  rights. 

The  examination  of  pupils  in  the  public  schools  with 
a  view  of  determining  their  hearing  power, — It  will 
not  be  denied  that  these  disabilities  among  pupils  should 
be  known  to  teachers  in  order  that  instruction  may  be 
made  more  successful,  and  it  therefore  becomes  important 
to  adopt  some  plan  for  correctly  determining  the  hear- 
ing power  of  all  school  children,  so  that  where  any  defect 
exists  •pupils  may  be  placed  under  the  best  possible 
advantages.  While  teachers  are  known  to  often  fail  to 
discern  marked  departures  from  the  normal  standard,  and 
children  themselves  cannot  always  give  reliable  infonna- 


tion,  yet  much  could  be  accomplished  by  principals  and 
teachers  were  they  assisted  at  the  start  by  an  expert  m 
such  matters,  especially  so  far  as  the  majority  of  pupjis 
are  concernedj;  but  where  it  becomes  important  to  ascer- 
tain the  exact  state  of  the  transmitting  apparatus  of  the 
ear,  and  the  condition  of  the  nerve-tract  connected  with 
audition,  an  expert  examination  would  be  required. 

The  importance  of  early  training  for  deaf  children, 
— Too  much  stress  can  scarcely  be  laid  on  the  value  of 
results  obtainable  in  this  way  if  early  made,  since  the  per- 
ceptive power  may  be  much  quickened  by  training  in 
many  instances,  even  where  the  middle  ear  apparatus  is 
defective.    It  would  appear  to  be  on  the  development  of 
the  perceptive  tract,  rather  than  on  any  change  in  the 
transmitting  mechanism,  that  mental  improvement  de- 
pends in  the  very  deaf  who  are  taught  aurally.  The 
expert  himself  finds  it  no  easy  task  to  get  at  the  facts  in 
certain  cases,  especially  in  young  children  who  have 
already  been  instructed  as  totally  deaf,  since  they  soon 
come  to  disregard  the  hearing  sense  entirely,  and  it  r^ 
mains  to  be  determined  in  such  cases  how  much  the 
auditory  nerve  has  deteriorated  from  disuse.     The  pro- 
fessed indifference  to  hearing  should  never  prevent  some 
attempts  being  made  at  instruction  through  the  hearing 
organs,  since  a  surprising  amount  of  hearing  may  thus  be 
found  to  exist     How  many  children  one  meets  with  who 
are  backward  in  learning  to  talk,  but  finally  on  getting  to 
be  three  or  four  years  old  gain  their   speech!    Such 
children  would  get  on  much  faster  in  many  instances,  it 
is  believed,  if  regarded  as  partially  deaf.     While  treating 
such  children  professionally  I  have  seen  beneficial  results 
from  the  use  of  conversation-tubes,  or  the  employment  of 
voice  at  close  range.     This  practice  cannot  be  too  early 
commenced.     I  have  observed  good  results  in  children 
as  young  as  eighteen  months.     In  observing  these  cases 
one  cannot  but  be  impressed  with  the  importance  of  nor- 
mal hearing  in  the  ready  acquirement  of  speech,  and 
that  however  imperfect  the  hearing  may  be,  it  has  its  uses 
in  acquiring  language. 

The  hearing  that  remains  after  injury  of  the  ear-drum. 
— Often  after  great  impairment  or  destruction  of  the 
transmitting  apparatus  of  the  ear-drums,  a  very  efficient 
passage  of  sound  to  the  auditory  nerve  remains ;  but  as  this 
becomes  more  and  more  difficult,  it  deteriorates  in  qual- 
ity, especially  for  long  distances,  until  finaUy  its  rendition 
in  the  very  hard-of-hearing  becomes  so  crude  and  inde& 
nite  that  interpretation  by  the  perceptive  tract  is  difficult 
or  even  impossible.  Now,  when  sound  ceases  to  be  trans- 
mitted in  this  manner,  hearing  may  take  place  by  means 
of  the  passage  of  sound  up  through  the  tissues  of  the  head 
to  the  perceptive  tract  as  propagated  by  means  of  die 
otacoustic  fan  [placed  on  the  tee&,  or  the  conversation- 
tube  placed  in  the  mouth.  In  the  former  instance  sound 
passes  more  directly  along  bone  structure  from  the  teeth, 
while  in  the  latter  it  ascends  to  the  vault  of  the  resonating 
chamber  at  the  top  of  the  pharynx  and  thence  up  through 
the  tissues  of  the  head.  Voice-sounds  imparted  to  a  pu- 
pil in  the  manner  just  mentioned  are  of  very  great  value 
in  certain  cases,  because  of  their  tones  being  natiu-al,  and 
the  pupil's  own  voice  is  even  rpore  effective  in  this  respect 
since  it  is  propagated  upward  with  much  energy  by  his 
own  vocal  efforts  against  the  moist  and  highly  receptive 
pharyngeal  vault 

27ie  classification  of  the  future. — No  time  should  be 
lost  in  taking  steps  in  this  direction ;  a  little  classification 
must  necessarily  pave  the  way  to  improvement  in  the 
education  of  the  deaf  of  every  degree.  It  should  be  kept 
in  mind,  however,  that,  in  a  certain  proportion  of  the 
partially  deaf,  the  defectiveness  is  transient  and  vari- 
able ;  and  that  in  some  of  the  more  difficult  cases  among 
the  very  or  totally  deaf,  repeated  examination  will  have 
to  be  made  when  any  doubt  as  to  the  diagnosis  remains. 

Before  quitting  this  subject  I  desire  to  mention  Bell's 
useful  device  for  testing  the  hearing. 

The  audiometer  arranged  by  Professor  BelL — ^This 
instrument,  for  all  practical  purposes  in  testing  the  hear- 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


679 


ing  power  of  the  different  classes  of  deaf  persons,  answers 
almost  every  requirement,  and  its  introduction  will  very 
much  facilitate  the  work  of  classification  when  used  by 
an  intelligent  and  trained  examiner. 


CHRONIC  PNEUMONIA,  PHTHISIS,  AND  MILL 
ARY  TUBERCULOSIS  IN  THE  LIGHT  OF 
RECENT  DISCOVERIES. 

By  EDMUND  C.  WENDT,  M.D., 

CURATOR  TO  THB  ST.   FRANOS  HOSPITAL,  NSW^YOKK. 

It  is  the  opinion  of  the  writer  that  the  micro-parasitic 
nature  of  genuine  tuberculosis  may  now  be  accepted  as 
proved  by  the  convincing  force  of  exact  experimental 
demonstration.  In  this  direction  few  will  to-day  attempt 
to  dispute  the  correctness  of  Koch's  well-known  asser- 
tions. But  practical  clinical  investigation  must  needs 
supplement,  modify,  or  perhaps  even  disprove  some  of 
the  later  claims  put  forward  by  Germany's  noted  mycolo- 
gist In  the  second  volume  of  the  Mittheilungen  aus 
dent  Reichsgesundheitsamt  Koch  has  recently  published 
more  extended  observations,  dealing  principally  with  the 
etiology  of  tuberculosis.  One  highly  important  statement, 
to  my  mind,  is  to  the  effect  that  the  repeated  entrance 
into  the  healthy  human  lung  of  small  numbers  of  the 
specific  bacilli  of  tuberculosis  results  in  chronic  phthisis, 
whereas  the  simultaneous  admission  of  numerous  microbes 
produces  acute  miliary  tuberculosis.  This  ingenious, 
significant,  and  far-reaching  hypothesis  certainly  requires 
corroborative  elucidation  at  the  hands  of  careful  clinical 
observation  before  it  can  command  universal  acceptance. 
Experiments  upon  animals  will  not  suffice  in  this  particu- 
lar instance  to  decide  the  matter  for  the  human  family. 
Above  all  things  it  remains  to  be  shown  how  and  when, 
in  the  individual  case,  the  dangerous  microbes  have 
effected  their  entrance  into  the  system.  Nor  can  we  tell 
as  yet  why  such  an  entrance  takes  place  so  easily  in 
some  cases,  indeed  occurs  in  a  certain  proportion  of 
them  with  all  the  certainty  of  an  inevitable  doom. 
Again  we  are  yet  ignorant  of  the  true  reason  why  the 
same  thing  happens  in  other  persons  with  tedious  diffi- 
culty, and,  as  it  were,  only  after  the  surmounting  of  for- 
midable opposition  on  the  part  of  a  struggling  constitu- 
tion. And  finally  we  have  but  very  inadequate  knowledge 
concerning  the  rationale  of  the  well-attested  fact  that  a 
large  class  of  persons  will  refuse  to  contract  phthisis  at 
all,  even  under  circumstances  seemingly  the  most  favor- 
able for  its  acquisition. 

These  and  other  practical  questions  that  suggest  them- 
selves in  connection  with  phthisis,  chronic  pneumonia, 
and  miliary  tuberculosis,  merit  the  earnest  attention  of 
the  medical  profession. 

Drs.  Biedert  and  Sigel  have  recently  devoted  much 
time  to  studies  in  this  direction,  and  the  results  of  a 
goodly  series  of  careful  clinical  observations  are  pub- 
lished by  them  in  the  current  number  of  Virchovd s  Archiv, 
The  cases  recently  published  by  Dr.  Kinnicutt  and  the 
writer  (see  The  Medical  Record,  October  ii  and  i8, 
1884)  also  show  that  the  practitioner  is  liable  at  any  time 
to  be  confronted  with  problems  that  may  seem  hopelessly 
puzzling,  unless  the  new  light  of  modem  pathology  can 
clear  away  the  obscurity  of  some  of  their  features. 

Biedert  and  Sigel,  in  the  article  alluded  to,  directed 
their  attention  chiefly  to  the  following  points  :  In  the 
first  place  they  tried  to  determine  the  relation  of  the  dis- 
covery in  the  sputum  of  tubercle-bacilli  to  the  different 
clinical  forms  of  consumption.  Thus  advanced  phthisis 
and  the  incipient  variety  would  presumably  differ  from 
each  other,  as  well  as  from  certain  other  pulmonary  pro- 
cesses partaking  of  the  nature  of  chronic  inflammation. 
Then  they  wished  to  ascertain  more  definitely  in  what 
manner  the  appearance  of  increasing  or  decreasing  pro- 
portions of  bacilli,  kept  pace  with  the  gross  physical 
changes  witnessed  in  their  patients.  And  again  they 
attempted  to  find  out  the  precise  conditions  of  the  first 


appearance  of  bacilli  in  the  sputum  of  persons  already 
afflicted  with  pulmonary  disease,  and  especially  what 
effects  were  observable  in  such  patients  while  living  for 
long  periods  in  the  same  rooms  or  wards  with  cases  of 
pronounced  phthisis. 

It  will  not  be  possible  here  to  follow  the  authors  through 
the  elaborate  details  of  their  painstaking  investigations. 
They  had  an  abundant  clinical  material  that  was  put  to 
the  best  possible  use  for  deciding  some  of  the  problems 
and  questions  here  barely  indicated.  The  conclusions 
drawn  from  their  observations  may,  however,  profitably 
engage  our  attention.  To  begin  with,  they  cannot  regard 
the  bacillus  tuberculosis  as  distinguishable  from  all  other 
bacteria  by  the  mere  peculiarity  of  its  shape.  They  are  not 
even  quite  certain  that  the  color-test  is  sufficiently  char- 
acteristic to  invariably  prevent  all  error.  But,  on  the 
other  hand,  they  fail  to  indicate  any  better  method  of  dif- 
ferential reco^ition.  In  pronounced  tubercular  phthisis, 
Koch's  bacilli  are  never  found  wanting  from  the  sputum. 
Indeed,  the  presence  of  these  microbes  is  the  essential  and 
vital  point  connected  with  that  disease.  Phthisis  being 
by  no  means  an  affection  that  always  starts  at  the  apex  of 
the  lung,  and  being,  moreover,  a  disease  with  at  times 
misleading  physical  signs,  the  discovery  of  the  specific 
micro- parasite  is  the  one  and  only  reliable  and  never-failing 
sign  of  its  actual  presence.  Obviously  the  importance  of 
this  point,  at  least  in  a  diagnostic  point  of  view,  can  hardly 
be  over-estimated.  It  amounts  to  the  de  facto  existence 
of  a  symptom  that  is  in  the  strictest  sense  pathognomonic. 
The  discovery,  in  a  given  case,  of  the  presence  of  tu- 
bercle bacilli  would,  then,  according  to  these  writers, 
have  all  the  binding  force  of  an  irrefragable  mathematical 
demonstration.  And  the  diagnosis  of  tuberculosis  would 
thus  be  capable  of  absolute  scientific  proof,  possibly  long 
before  the  grosser  methods  of  physical  examination  could 
have  revealed  it. 

But  there  occur,  as  we  all  know,  obscure  cases  of  in- 
sidious disease  that  are  by  many  regarded  as  latent 
phthisis  or  possibly  incipient  consumption.  The  ab- 
sence of  bacilli  in  them  would  show  that,  as  yet,  tuber- 
culosis is  not  present.  Indeed,  non-specific  pulmonary 
infiltrations  probably  always  precede  the  tubercular  in- 
vasion. And  there  can  be  no  doubt  that  such  non-bacil- 
lary  infiltrations  may  and  commonly  do  accompany  the 
specific  lung  lesions  of  true  tuberculosis.  The  prepon- 
derance of  one  or  the  other  of  these  distinct  morbid  pro- 
cesses may,  perhaps,  be  gauged  by  comparing  physical 
signs  with  the  proportion  of  bacilli  discoverable  in  the 
sputum. 

In  the  course  of  the  disease  the  non-specific  lesion 
may  asstune  the  important  rdle  of  acting  as  a  barrier 
against  the  further  encroachments  of  bacillary  infiltra- 
tion. On  the  other  hand,  it  may  happen  that  a  compara- 
tively  harmless,  because  non-specific  infiltration  will 
furnish  suitable  soil  for  the  growth  and  multiplication  of 
the  bacilli,  and  in  that  way  exert  a  baneful  influence  on  the 
health  of  the  patient  by  its  subsequent  conversion  into 
a  specific  infiltration. 

The  process  which  prepares  the  lung  for  the  favorable 
reception  of  the  bacilli  is  in  itself  a  pathological  one,  be- 
ing characterized  by  distinct  cellular  hyperplasia.  It 
is  noticeable  that  many  of  the  new-formed  cells  have  a 
spontaneous  tendency  toward  degeneration.  Nor  can  they 
long  resist  the  virulent  attacks  of  the  micro-parasites.  It 
would  seem,  however,  that  the  latter  are  impotent  to 
harm  healthy  cells.  Indeed,  they  sooner  or.  later  perish 
in  any  conflict  with  normal  tissue. 

Biedert  and  Sigel  further  conclude  from  their  observa- 
tions that  phthisis  is  not  an  infectious  malady,  and  very 
certainly  not  a  contagious  one,  in  the  usual  sense.  For 
consumption  owes  its  origin  not  solely  to  the  agency  of 
an  infectious  virus  upon  a  healthy  organism.  It  dis- 
tinctly needs  preparatory  changes,  such  as  a  vitiated  con- 
stitution, lungs  already  damaged,  or  other  predisposing 
elements,  before  a  bacillary  invasion  can  take  hold  and 
work  further  evil. 


68o 


THE  MEDICAL  RECORD. 


[December  20,  1884. 


Even  miliary  tuberculosis  has  not  been  clinically  shown 
to  depend  upon  the  introduction  of  large  numbers  of 
bacilli  into  previously  healthy  human  lungs.  Here,  too, 
some  morbid  change  must  have  been  pre-wrought  before 
the  accidental  inhalation  of  specific  microbes  can  prove 
the  starting-point  of  rapidly  fatal  disease. 

If  we  accept  as  trustworthy  the  statements  of  these 
authors,  it  follows  that  the  prophylaxis  and  rational  treat- 
ment of  phthisis  are  likely  to  remain  in  the  near  future, 
what  they  have  been  in  the  near  past.  That  is  to  say, 
our  attention  must  be  directed  chiefly  toward  constitu- 
tional improvement,  with  such  hygienic  and  local  meas- 
ures as  common-sense  will  dictate. 

An  anti-tubercular  specific  does  not  exist,  and  even 
should  one  be  discovered  it  would  be  found  impotent  in 
those  frequent  cases  where  a  vitiated  constitution,  an 
hereditary  taint,  lack  of  food,  and  unsanitary  surround- 
ings more  than  suffice  to  doom  the  poor  human  sufferer 
to  an  early  grave.  We  may  remember  in  this  connection 
the  words  of  Eisenmann  :  **  Tubercles  are  but  the  tears 
of  the  poor  shed  within/*  It  is  not  the  wish  of  the  writer 
to  add  to  the  length  of  this  paper,  which  is  based  chiefly 
on  the  article  of  Biedert  and  Sigel,  by  an  account  of  his 
own  observations.  The  latter,  although  quite  insignificant 
numerically,  when  compared  with  those  of  the  authors 
mentioned,  have  nevertheless  strengthened  his  belief  in  the 
substantial  correctness  of  their  views.  Certainly  there  is 
a  large  field  for  further  work  here,  a  field  rich  in  promise 
of  practical  results.  It  is  to  be  hoped  that  the  ground 
will  not  be  allowed  to  lie  fallow,  and  that  our  own  coun- 
try may  contribute  its  contingent  of  faithful,  tireless  tillers 
in  the  twin  cause  of  humanity  and  science. 

Th«  Kensington,  loa  East  Fifty-sevknth  Street, 
December  13,  1884. 


AN  ANOMALY  OF  A  VERTEBRA, 

With  a  Suggestion  Regarding  the  Causation    of 
Certain  Forms  of  Spinal  Irritation. 

By  E.  C.  SPITZKA,  M.D., 

PROFESSOR     OP    NEURO-ANATOMY     AND     PHYSIOLOGY     IN    THE    NEW    YORK    POST- 
GRADUATE MEDICAL  SCHOOL. 

While  examining  some  specimens  in  the  anatomical 
collection  of  Professor  William  Darling,  M.D.,  F.R.C.S., 
of  this  city,  I  was  struck  by  a  peculiarity  of  one  of  the 
vertebrae,  which,  without  claiming  a  complete  knowledge 
of  the  recorded  anomalies,  I  believe  has  not  been  de- 
scribed. At  all  events,  attention  is  not  directed  to  it 
in  any  of  the  accessible  handbooks. 


I.— Lateral  view  of  the  specimen ;  ♦,  the  right  prong. 


The  specimen  is  in  all  respects  a  typical  tenth  dorsal 
vertebra,  as  is  shown  by  its  having  a  demi-facet  on  the 
upper  margin  of  the  body,  and  a  costal  facet  on  the 
transverse  process.  The  spiny  rugosities  on  the  upper 
part  of  the  posterior  face,  and  the  lower  part  of  the  an- 
terior face  of  the  arch,  are  very  prominent ;  the  texture 
of  the  bone  appears  normal. 

On  the  anterior  face  of  the  arch,  immediately  above 


the  inferior  articular  processes,  two  powerful  prongs  of 
bone  jut  downward,  as  if— in  the  recent  state,  when  the 
vertebrae  were  connected — to  overlap  the  superior  artic- 
ular process  of  the  next  vertebra  below.  The  disposi- 
tion and  dimensions  of  these  prongs  are  so  evident  from 
the  accompanying  drawings,  which  are  of  the  natural  size, 
that  I  do  not  consider  it  necessary  to  tire  the  reader  with 
a  list  of  measurements. 

Regarded  laterally,  it  is  clear  that  these  processes  must 
have  encroached  (particularly  when  the  periosteal  lining 
is  considered  to  have  been  added)  on  the  calibre  of  the 
intervertebral  foramina  (Fig.  i).  Regarded  from  above, 
it  is  equally  clear  that  they  must  have  encroached  on  the 
spinal  canal,  whose  contents  here  consist  not  alone  of 
the  cord  and  its  membranes,  but  also  of  enormous  de- 
scending nerve-trunks. 


Fig.  3. — Basilar  view  of  same,  slightly  tilted,  so  as  to  expose  the  anterior  Cue 
of  the  arch. 

In  Fig.  2  the  vertebra  is  represented  as  seen  from 
below,  to  illustrate  the  origin  of  the  "  prongs  "  from  the 
upper  (cephalic)  contour  of  the  inferior  articular  pro- 
cesses. Their  mternal  edge  merges  into  the  rugae  on 
the  anterior  face  of  the  arch,  of  which  they  are  probably 
hypertrophied  continuations.  The  dorso- ventral  face  of 
the  right  prong  turned  toward  the  facet  of  the  inferior 
articular  process  was  rough,  and  showed  an  approach  to 
the  stalactite-like  structure  of  the  rugosities  to  which  the 
vertebral  ligaments  are  attached.  This  resemblance  in- 
dicates to  my  mind  the  origin  of  these  processes,  namely, 
an  ossification  extending  into  the  ligamentous  structures, 
uniting  the  articular  parts  of  the  arches.  That  such  a 
contrivance  would  render  dislocation  of  the  arches  im- 
possible is  evident,  and  comparative  anatomy  furnishes 
more  than  one  instance  of  a  parallel  proviso  on  the  part 
of  the  vertebral  fastenings. 

The  left  upper  articular  process  had  an  extension  of 
bone  glued  to  its  anterior  face,  the  separation  was  well 
indicated  by  the  different  character  of  the  bone,  and  a 
daep  ravine  between  them. 

From  the  fact  that  the  symptoms  of  spinal  irritation 
are  often  localized  around  a  single  or  one  or  two  verte- 
brae, mechanical,  thermal,  or  electrical  applications  to 
which  often  suffice  to  modify  or  provoke  the  numerous 
and  variable  subjective  (and  objective  vaso-motor)  symp- 
toms of  that  disorder,  it  would  seem  plausible  to  connect 
this  state  with  some  irritating  cause  operating  on  the 
nerves  at  their  exit,  or  the  membranes  of  the  cord  and 
nerve-roots  within  the  spinal  canal.  Injuries  to  the  verte- 
bral column,  notably  to  the  coccyx — as  in  three  cases  in 
my  experience — are  competent  to  provoke  such  symp- 
toms, and  it  is  not  unlikely  that  such  an  hypertrophy  of 
bone  tissue  as  that  described  here  may  accompany  or— 
developing  spontaneously— cause   this  disorder.      The 


December  20,  1884.] 


^THE   MEDICAL  RECORD. 


681 


evil  and  apparently  disproportionate  effect  of  spiculae 
pressing  on  the  cranial  dura,  is  an  acknowledged  dogma 
of  neuropathology,  and  the  analogy  between  that  dogma 
and  the  explanation  of  spinal  irritation  here  suggested  is 
very  great.  In  both  cases  the  essential  nervous  tissues 
are  not  destructively  involved,  the  primary  tissue  to  suf- 
fer is  the  fibrous  envelope.  In  both  cases  this  fibrous  en- 
velope is  supplied  by  nerves  whose  deep  origin  is  in  the 
contained  neural  viscus,  and  in  both  the  functional  effect 
is  remote  and  usually  manifests  itself  in  the  vaso-motor 
realm. 

Six  years  ago  I  had  referred  to  me,  by  Dr.  H.  Knapp, 
a  school-teacher  from  the  Carolinas,  who  suffered  from 
aggravated  spinal  irritation.  I  became  satisfied  that  a 
fracture  or  distortion  of  the  upper  part  of  the  coccyx  was 
the  fundamental  cause  of  her  malady,  and  at  my  sugges- 
tion Dr.  James  L.  Little  removed  the  part  below  the 
point  of  union,  which  latter  was  at  right  angles.  The 
patient  returned  to  her  home,  and  Dr.  Knapp  informed 
me  that  she  was  relieved  of  all  her  nervous  symptoms. 
What  is  shown  to  be  true  of  the  coccyx  in  this  case,  where 
the  sublaid  causd  tollitur  effecius  argument  was  so  hap- 
pily illustrated,  is  probably  true  of  the  more  important 
parts  of  the  vertebral  column. 

The  condition  of  the  vertebrae  and  their  ligamentous 
structures  has  not  been  studied  in  connection  with  spinal 
irritation,  and  this  very  naturally,  as  such  a  study  is  dif- 
ficult, involves  much  mutilation  in  a  hurried  autopsy,  and 
autopsies  in  cases  of  spinal  irritation  are  at  best  few. 
Nothing  is  known  of  the  clinical  history  of  the  subject 
from  whom  this  bone  was  derived,  nor  are  other  parts  of 
its  skeleton  identifiable  in  the  collection. 

To  Professor  Darling  my  thanks  are  due  for  the  loan 
of  the  specimen  from  which  the  accompanying  drawings 
were  made  by  the  author. 

i^00teBB  tit  p^ejfltjcal  ^jcieiijce. 

Tuberculosis  of  the  Eye. — The  Revue  Medicate^ 
October  18,  1884,  gives  the  case  of  a  child  who,  eight 
weeks  after  an  injury  to  the  eye,  showed  cheesy  masses 
on  the  conjunctiva  near  the  external  canthus.  On  mi- 
croscopical examination  they  were  found  to  be  tubercu- 
lar infiltrations.  The  same  journal  also  contains  the 
following  general  remarks  regarding  ocular  tuberculosis. 
The  eye  niay  be  invaded  by  tubercle  either  primarily  or 
secondarily.  Every  part  of  the  organ  where  vascular 
tissue  occurs  may  become  the  seat  of  tubercle.  Thus  it 
has  been  found  in  the  iris,  choroid,  conjunctiva,  and  once 
or  twice  primary  tubercle  has  been  observed  in  the 
retina.  The  ciliary  body  may  also  be  invaded  by  pri- 
mary or  secondary  tubercle,  the  latter  usually  following 
a  tubercular  granuloma  of  the  iris.  * 

A  Frknch  Treatment  for  Ulcer  of  the  Leg. — 
Dr.  Vidal  recommends  {JO  Union  MSdicale,  October  12, 
1884)  the  following  treatment,  which  he  has  found  very 
efficacious,  especially  for  indolent'  ulcers  with  pale  base 
and  ichorous  secretion  :  First,  wash  the  ulcer  with  an  in- 
fusion of  oak-leaves,  then  cover  with  a  layer  of  subcar- 
bonate  of  iron.  A  poultice  of  potato  starch  is  then  ap- 
plied and  retained  by  a  roller  bandage.  Healing  is 
complete  in  from  ten  to  forty  days.  The  subcarbonate 
of  iron  has  an  action  upon  the  ulcer  at  the  same  time 
astringent  and  tonic.  It  gives  new  life  and  activity  to 
the  tissues.  The  galvanometer  shows  ia  considerable 
giving  off  of  electricity,  which  explains,  according  to  the 
author,  the  beneficial  action  of  the  iron. 

KXPERIMENTAL    StUDY    OF    ChRONIC    ALCOHOLISM. — 

For  the  past  three  years  Dujardin-Beaumetz  and  Andig6 
have  been  engaged  in  studying  the  effects  of  alcohol, 
chiefly  upon  pigs.  The  hog  was  chosen  on  account  of 
the  resemblance  of  the  alimentary  system  with  that  of 
inan,  and  for  the  further  reason  that  the  alcohol  could  be 
readily  given.     A  variety  of  alcohols  were  experimented 


with,  ranging  from  the  high  grade  ethylic,  at  one  hundred 
per  cent,  to  the  low  grade  beet-root,  at  thirty-four  per 
cent.  The  daily  dose  was  from  one  to  two  drachms  to 
every  ten  pounds  of  live  weight.  This  was  given  for 
thirty  months,  mixed  with  their  daily  food.  In  the  in- 
toxication produced,  the  stage  of  excitement  was  want- 
ing, stupor  being  the  first  effect  The  changes  observed 
consisted  in  congestion  and  inflammation  of  the  intes- 
tines, hyperaemia  of  the  liver — not,  however,  going  on  to 
interstitial  hepatitis — pulmonary  congestion,  and  intra- 
muscular hemorrhage.  Haematuria  and  albuminuria  were 
never  present.  The  heart  and  kidneys  were  found  fatty 
at  times,  but,  as  Cornil  has  previously  shown,  this  is  an 
almost  constant  condition  in  the  pig.  The  lesions  were 
much  less  marked  in  those  experimented  upon  with  the 
rectified  and  ethylic  alcohols  than  in  those  given  the 
poorer  beet-root  and  potato  alcohols. — L'  Union  Midi- 
caUy  October  2,  1884. 

The  Dyspncea  of  Bright's  Disease. — A  communi- 
cation on  the  varieties  of  dyspncea  met  with  in  Bright* s 
disease,  by  Dr.  Howard,  of  the  McGill  University  (Can- 
ada Medical  and  Surgical  Journal^  November,  1884)^ 
illustrates  the  following  points  :  i.  That  marked  dyspnoea 
may  occur  in  Bright's  disease  not  due  to  gross  lesions  in 
the  lungs,  pleura,  or  heart — such  as  inflammation  or 
oedema  of  the  lungs,  hydrothorax,  or  pleurisy  with  ef- 
fusion, endo-  or  peri-carditis,  or  valvular  disease.  2. 
That  it  may  be  a  continuous  dyspncea,  or  of  paroxys- 
mal character,  resembling  ordinary  spasmodic  asthma; 
and  that  these  types  may  occur  in  the  same  ^case,  al- 
though, in  my  experience,  the  continued  variety  is  more 
frequent  than  the  asthmatic.  3.  That  these  forms  of 
dyspnoea  may  occur  as  the  prominent  symptoms  of  renal 
disease,  and  their  origin  may  escape  recognition  if  the 
urine  be  not  carefully  examined,  as  well  as  the  heart  and 
pulse.  4.  That  Cheyne-Stokes  respiration  is  often  a 
symptom  of  Bright's  disease,  and  that  it  obtains  in  both 
acute  parenchymatous  and  in  chronic  interstitial  ne- 
phritis. 5.  That  while  usually  an  evidence  that  the 
fatal  issue  is  near  at  hand,  it  may  occur  in  a  chronic 
form,  and  may  occur  for  weeks,  perhaps  even  for  years. 
6.  That  these  several  forms  of  dyspnoea  just  mentioned 
are  very  probably  due  to  that  defective  renal  elimination 
called  uraemia.  7.  That  in  the  acute  forms  of  Bright's 
disease,  serious  or  fatal  dyspncea  sometimes,  but  rarely, 
occurs  in  connection  with  effusion  into  the  submucous 
membrane  of  the  larynx  (oedema  glottidis). 

Do  Calcareous  Concretions  of  the  Lungs  con- 
tain Bacilli  ? — The  Paris  correspondent  of  the  British 
Medical  Journal  writes  that  M.  D^jerine  has  made  a 
series  of  researches  to  ascertain  if  the  bacillus  of  tuber- 
culosis is  present  in  the  calcareous  concretions,  sur- 
rounded by  a  zone  of  interstitial  pneumonia,  often  ob- 
served at  the  apex  of  the  lungs  of  old  people.  There  are 
different  varieties  of  thes^  concretions ;  some  are  as  hard 
as  stone,  others  calcareous  and  cheesy,  or  as  soft  as 
pulp.  In  veritable  cretaceous  concretions,  M.  D6jerine 
only  once  ascertained  the  presence  of  two  or  three  ba- 
cilli ;  these  were  used  for  inoculating  rabbits,  which,  af- 
ter seven  months'  interval,  were  entirely  free  from  tuber- 
culous lesion.  In  the  calcareous  cheesy  masses  the 
cretaceous  concretion  is  always  in  the  centre  of  the 
cheesy  portion.  M.  D6jenne  invariably  detected  bacilli 
in  the  non-calcareous  part,  and  they  contained  more 
spores  than  the  bacilli  of  a  tuberculous  lesion  in  the  pro- 
cess of  evolution.  These  remains  of  an  arrested  disease 
of  parasitic  origin  are  of  special  interest,  as  an  examina- 
tion may  establish  the  distinction  between  the  cheesy 
calcareous  masses  of  tuberculosis,  and  similar  degenera- 
tions found  at  the  necropsies  of  syphilitic  patients.  M. 
D6jerine  observes  that  the  absence  of  bacilli  does  not 
necessarily  prove  that  tuberculosis  does  not  exist;  he 
has  been  unable  to  detect  the  presence  of  a  single  ba- 
cillus, although  the  necropsy  clearly  demonstrated  the 
presence  of  tuberculosis.     M.  Malassez   says  that   the 


682 


THE   MEDICAL  RECORD. 


[December  20,  1884. 


spores  of  bacilli  appear  or  disappear  according  to  the 
coloring  substance  used.  If  fuchsine  be  used  they  as- 
sume the  appearance  of  unbroken  rods ;  if  gentian  vio- 
let, of  spotted  rods  or  a  row  of  seeds.  This  difference 
of  aspect  may  be  interpreted  in  two  different  ways ;  it  is 
possible  that  the  substance  which  unites  the  seeds  or 
spots  can  be  colored  by  fuchsine  and  not  by  gentian  it 
is  also  possible  that  the  appearance  is  an  optical  effect 
due  to  the  nature  of  the  coloring  substance. 

Nephrectomy  in  Infants.— At  a  recent  meeting  of 
the  London  Clinical  Society,  Dr.  Godlee  reported  a  case 
of  nephrectomy  done  in  an  infant.  The  child,  a  boy, 
aged  one  year  and  ten  months,  was  admitted  under  his 
care  at  the  Northeastern  Hospital  for  Children  in  August, 
i^^3««B|The  tumor  was  first  noticed  in  June,  1883,  ^"^ 
was  growing  rapidly.  It  was  on  the  right  side,  and 
measured  four  inches  in  the  long  diameter  and  about  two 
in  the  short.  It  was  freely  movable,  and  manipulation 
caused  no  pain.  There  were  no  urinary  symptoms  at  all. 
The  kidney  was  removed  by  the  lateral  abdominal  (Lan- 
genbuch's)  incision,  and  was  readily  accomplished,  as 
there  were  no  adhesions  to  surrounding  structures.  The 
C3ecum  and  the  duodenum  were  the  only  pieces  of  bowel 
exposed.  One  large  vein,  which  ran  over  the  tumor,  alone 
required  ligature.  There  was  no  hemorrhage  of  conse- 
quence, and  the  whole  operation  was  concluded  in  half 
an  hour.  The  child  had  no  symptoms  of  any  kind  after 
the  operation.  It  ate  and  slept  as  well  the  next  day  as 
before,  and  the  temperature  only  rose  to  99°  once,  the 
day  after  the  operation.  It  left  the  hospital,  well,  six  days 
later.  It  continued  well  till  February,  1884,  when  recur- 
rence took  place  in  the  right  iliac  fossa  and  rapidly  in- 
creased in  size,  passing  down  into  the  scrotum,  and  the 
child  died  soon  after.  Dr.  Godlee  mentioned  eight  other 
cases  which  have  been  recorded,  showing  that  of  them 
five  had  died  of  the  immediate  result  of  the  operation,  two 
had  recovered  well,  but  died  afterward  of  a  recurrence, 
and  one  was  well  when  last  heard  of,  but  notwithstanding 
the  unsatisfactory  nature  of  the  results  he  argued  that, 
seeing  how  hopeless  the  condition  is  if  left  alone,  we 
should  endeavor  to  remove  these  tumors  in  a  still  earlier 
stage,  at  all  events  until  it  is  proved  that  even  this  pro- 
ceeding is  invariably  followed  by  a  fatal  result.  He 
particularly,  however,  pleaded  against  attempting  the 
removal  of  the  very  large  growths  which  are  not  unfre- 
quently  met  with,  showing  that  they  will  almost  certainly 
have  involved  surrounding  structures,  and  that  thus  while 
no  good  can  follow  the  operation  an  immediately  fatal 
result  is  probable.  The  tumor  weighed  about  one  pound, 
and  was  in  structure  a  mixed  sarcoma,  most  of  the  cells 
being  roundish  or  oval,  but  some  spindle-shaped.  This 
is  probably  the  usual  composition  of  these  growths,  but 
another  class  was  mentioned  in  which  striped  muscular 
fibres  occur.  The  latter  are  probably  congenital,  and 
often  affect  both  kidneys,  and  are  thus  not  favorable  for 
surgical  interference. 

Blood-Poisoning  Following  Human  Bites. — The 
Paris  correspondent  of  the  London  Lancet  reports  two 
cases  of  this  kind,  which  serve  to  illustrate  the  danger 
sometimes  attending  the  infliction  of  human  bites.  A 
lad  of  eighteen,  employed  as  a  waiter  at  a  public-house, 
was  guilty  of  some  misdemeanor,  and  while  his  employer 
was  remonstrating  with  him,  the  lad,  fearing  a  thrashing, 
took  hold  of  the  right  hand  of  his  master  and  bit  him 
severely  on  the  thumb.  The  publican  dismissed  the  lad 
on  the  spot,  had  his  thumb  dressed,  and  thought  no  more 
about  the  matter.  But  about  two  months  after  the  bile 
phlegmonous  inflammation  set  in,  and  the  patient  was 
carried  off  in  a  few  hours,  death,  according  to  the  medical 
attendant,  having  been  caused  by  blood-poisoning.  In  a 
recent  quarrel  between  two  newspaper  editors  in  Paris, 
one  bit  the  hand  of  the  other,  soon  after  which  lymphan- 
gitis set  in  in  the  arm  of  the  wounded  patient,  which  was 
accompanied  by  symptoms  of  erysipelas,  from  which,  how- 
ever, he  soon  recovered. 


Muscular  Rupture  simulating  Abscess.— Dr.  Pho- 
cas  relates,  in  La  France  Midicale^  September  25, 1884^ 
a  case  of  rupture  of  muscles  in  the  lumbar  region  which 
simulated  abscess  and  caused  symptoms  similar  to  those 
of  lateral  curvature  of  the  spine.  The  patient,  a  young 
man,  had  first  experienced  pain  in  the  left  side.  Three 
weeks  later  he  began  to  walk  with  a  lintip  and  lean  to  the 
left  side.  He  was,  therefore,  examined  for  lateral  curvar 
ture.  This  was  not  found  to  exist,  but  a  swelling  to  the 
left  of  the  spinal  column,  painful  on  pressure  and  fluctuit- 
ing  in  its  central  part,  was  made  out  After  repeated  ex- 
aminations it  was  regarded  as  an  abscess  and  operated 
upon  under  chloroform.  Careful  dissection  brought  to 
light  a  rent  in  the  lumbar  aponeurosis,  through  which  a 
hernia  of  the  mass  of  sacro-lumbar  muscles  protnded. 
Underneath  this  hernia  was  a  tumor  covering  the  quad- 
ratus  lumborum,  and  adherent  to  its  outer  border,  as 
well  as  to  the  abdominal  muscles  and  aponeurosis.  The 
tumor  measured  about  two  inches  in  diameter,  was  of  a 
yellowish  color,  of  soft  consistence,  and  fibrous  aspect 
Under  the  microscope  it  was  found  to  be  composed  of 
altered  muscular  and  fibrous  tissue.  The  patient  made 
a  good  recovery,  and  was  soon  able  to  leave  the  hospital, 
free  from  any  signs  of  curvature,  lameness,  or  deformity. 

Scleroses  of  the  Coronary  Arteries. — This  con- 
dition has  received  more  attention  of  late  from  both 
pathologists  and  clinicians,  since  the  connection  between 
pathological  changes  in  the  muscular  tissue  of  the  heart 
and  diseases  of  its  vessels  has  been  better  understood. 
Samuelson  found  that  cutting  off  the  circulation  in  the 
coronary  arteries  caused  a  notable  diminution  in  the 
force  of  the  cardiac  contractions,  and  a  corresponding 
lowering  of  the  blood-pressure,  while   in  some  experi- 
ments by  Cohnheim  and  Schulthess-Rechberg  the  heart 
continued  to  beat  forcibly  but  somewhat  irregularly  and 
then  suddenly  stopped.     The  diseases  of  these  vessels 
have  been  classified  and  described  by  Leyden  upon  the 
basis  of  an  extensive  clinical  experience.     Pathologically 
he  distinguishes  :   i.  Sclerosis  or  ossification  of  the  cor- 
onary arteries  without  any  other   cardiac   lesion.    The 
muscular  wall  is  not  diseased,  and  death  occurs  from 
some  intercurrent  affectioUr     2.  Acute  thrombotic  soften- 
ing or  hemorrhagic  infarction  of  the  cardiac  muscle  fol- 
lowing sclerotic  thrombosis  of  the  coronary  arteries— 
myomalacia  cordis  of  Ziegler.     This  leads  eventually  to 
fatty  degeneration  or  softening  of  the  region  supplied  by 
the  occluded  vessels,  which  is  the  most  frequent  cause  of 
rupture  of  the  heart.     3.  The  chronic  form,  fibrous  de- 
generation of  the  muscular  tissue — myocarditis  fibrosa— 
arising  from  induration  of  the  diseased  vascular  territoiy. 
At  the  apex  aneurism  of  the  heart  frequently  arises  from 
this  cause.     4.  A  combination  of  these  several  lesions. 
This  is  the  most  frequent  condition. 

Clinically  these  varieties  occur  in  a  more  or  less  acote 
or  chronic  form.  The  author  divides  them  into  :  i.  Cases 
running  an  acute  course  and  ending  in  sudden  deatL 
Death  occurs  in  syncope  or  after  an  attack  of  angina 
pectoris.  The  autopsy  shows  sometimes  very  marked, 
and  sometimes  very  insignificant,  anatomical  changes  in 
the  heart-walls.  These  are  rupture  of  the  heart,  san- 
guineous infiltration  with  efiiision  of  blood  into  the  peri- 
cardium, softening  of  the  heart,  or  small  patches  of  fatty 
degeneration  in  the  muscular  wall.  To  this  form  belong 
the  cases  described  in  the  literature  as  embolism  of  ^ 
coronary  arteries,  a  frequent  symptom  of  which  is  a  mark- 
edly slow  pulse,  or  sudden  paralysis  of  the  heart  may 
occur.  2.  The  subacute  form,  in  which  the  course  of 
the  disease  embraces  a  period  of  several  weeks.  The 
early  symptoms  are  cough,  shortness  of  breath,  oppres- 
sion, often  attacks  of  angina  pectoris,  and  sometimes 
dropsy.  A  slight  improvement  occurs,  then  the  symp- 
toms return  with  great  severity  and  death  ensues.  After 
death  we  find  myomalacia,  sanguineous  infiltration,  fat^ 
degeneration,  and  old  fibrous  bands.  3.  The  chronic 
cases  usually  described  as  chronic  myocarditis,  fibrous 
myocarditis,  dilatation  or  aneurism  of  the  heart.    In  per- 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


683 


sons  of  advanced  age  cardiac  symptoms  appear  gradually, 
having  periods  of  abeyance.  These  symptoms  are  those 
of  angina  pectoris  or  cardiac  asthma.  The  course  is  al- 
ways progressive,  and  as  the  symptoms  become  more 
severe  the  patient  presents  a  picture  of  severe  heart  dis- 
ease. The  asthma  increases,  dropsy  occurs,  and  some- 
times in  delirium,  sometimes  suddenly,  usually  after  suffer- 
ing for  several  years,  the  patient  succumbs. 

Thus  sclerosis  of  the  coronary  arteries  presents  itself 
as  an  acute  or  chronic  disease,  with  more  or  less  severe 
cardiac   symptoms,  occurring  late  in  life,  and  indepen- 
dently of  any  valvular  lesions.     The  heart  symptoms  are 
vital  or  physiological  rather  than  physical.     These  are 
angina  pectoris,  asthma,  cardiac  weakness,  syncope,  and 
changes  in  the  frequency  and  rhythm  of  the  pulsations, 
.     the  pulse  being  sometimes  reduced  to  eight  in  the  minute. 
The  physical  sign  is  that  of  dilatation  of  the  left  ventricle, 
with,  usually,  hypertrophy  of  the  right.     The  signs  on 
the  part  of  the  respiratory  system  are  cough,  dyspnoea, 
pulmonary  engorgement,  and  occasionally  also  oedema 
of  the  lungs.     The  chief  cause  of  the  disease  is  heredity, 
although  the  abuse  of  alcoholic  liquors  and  high  living 
play  a  certain  rdle  in  its  production.     Prolonged  mental 
and  physical  exertion  is  also  to  be  reckoned  among  the 
causes,  and  the  author  lends  the  weight  of  his  authority 
to  the  popular  belief  of  a  "  broken  heart "  from  grief  and 
anxiety. — Centralblati  fur  Klinische  Medicin^  No.   38, 
1884. 

The  Etiology  of  Trichorrhexis  Nodosa. — In  op- 
position to  the  opinion  of  Eichhorst,  who  has  recently 
written   upon  this  condition,  Dr.  Wolffburg  states  that 
the  sole  cause  of  trichorrhexis  nodosa  is  the  improper 
care  of  the  hair.     He  showed  in  his  own  person  that  it 
could  be  produced  in  the  beard  on  one  side  by  rubbing 
it  energetically  and  frequently,  the  other  side  meanwhile 
being  normal.   The  following  are  the  grounds  upon  which 
the  author  bases  his  belief"  in  the  mechanical  causation 
of  trichorrhexis    (Centralhlait  fur  Klinische  Medicitiy 
No.    ^Zy    1884) :    I.  The  anatomical   appearances — the 
hair,  except  for  the  nodules,  is  healthy.    2.  The  localiza- 
tion— the  affection  has  hitherto  been  observed  only  in 
the  larger  hairs  of  the  beard,  and  especially  in  those  so 
situated  as  to  be  most  exposed  to  mechanical   injury 
when  the  face  is  rubbed,  as  in  the  beard  covering  the 
lower  jaw.     3.    The   explanations   hitherto  offered  are 
insufficient.     4.  The  supposed  incurability  of  the  affec- 
tion is  easily  explained  when  one  remembers  that  the 
treatment  usually  recommended  (frictions  with  alcoholic 
preparations   or  irritating    salves)    only  furnished   new 
sources  of  irritation  to  the  ill-treated  beard. 

The  Prognosis  of  Spinal  Curvatures. — ^The  fol- 
lowing are  the  principal  conclusions  of  M.  Pravaz  in  a 
recent  article  on  the  curability  of  deviations  of  the  spinal 
column   {^Centralblati  fUr  Chirurgie^  No.  39,  1884)  :  Of 
special  importance  in  the  prognosis  of  curvatures  of  the 
spine  is  the  condition  of  the  general  health.     The  exist- 
ence of  any  dyscrasia,  especially  of  chlorosis,  renders  the 
prognosis  less  favorable.     For  in  an  individual  suffering 
from  nial-assimilation  the  skeleton  is  not  sufficiently  re- 
sisting to  maintain  the  good  results  obtained  by  the  use 
of  apparatus  ;  and  sometimes  in  these  cases  there  are 
such  disorders  o{  circulation  as  to  interfere  with  the  use 
of  supports.     In  general,  the  younger  the  individual  the 
more  easily  is  the  deformity  overcome,  yet  it  is  the  rule 
that  the  treatment  must  be  longer  continued  in  children 
than  in    adolescents,  as  it  is  less  easy  to. adjust  the  appa- 
ratus  for   them  land  the  liability  of  relapses  is  greater. 
The  author  opposes  forcibly  the  widespread*  error  that 
curvatures  of  the  spine  will  disappear  as  the  child  grows 
older.     The  curvatures  following  pleurisy  are  of  unfavor- 
able prognosis,  as  are  also  those  produced  by  paresis  of 
the  spinal  muscles.     Of  the  deformities  caused  by  dis- 
ease of  the  osseous  system  those  due  to  rachitis  present 
the  greatest  difficulties  in  the  way  of  treatment,  for  unless 
the^deformity  be  overcome  before  the  period  of  ebunra- 


tion  its  correction  becomes  almost  impossible.  The 
prognosis  of  ordinary  scoliosis  depends  greatly  upon  the 
amount  of  rotation  present.  When  taken  early  in  hand 
a  curvature  of  even  considerable  extent  may  be  over- 
come, as  soon  as  the  general  health  is  improved.  The 
prognosis  of  a  dorsal  curvature  is  more  favorable  than 
that  of  a  lumbar  deviation.  Other  things  being  equal,  the 
curvatures  with  a  long  radius  offer  greater  chances  of 
cure  than  those  with  a  short  radius.  This  is  because  in 
the  latter  case  the  individual  vertebrae  are  m6re  wedge- 
shaped,  and  consequently  are  less  likely  to  become  re- 
stored to  their  normal  dimensions. 

The  Antidote  for  Resorcin. — It  having  been  re- 
marked that  in  resorcin  poisoning  the  arteries  were 
nearly  empty  while  the  veins  were  engorged,  Dr.  Justus 
Andeer  proposed  the  use  of  hot  baths  in  order  to  de- 
plete  the  venous  systenj.  He  found,  however,  on  experi- 
ment, that  warm  baths  rather  increased  the  severity  of 
the  symptoms  caused  by  the  resorcin  poisoning.  After 
casting  about  in  several  directions  for  an  antidote,  he 
finally  discovered  that  the  very  best  was  good  red  wine 
— either  Bordeaux  or  Burgundy.  This  acted  equally 
well  in  slight  and  severe  [cases  of  poisoning  from  this 
substance.  The  author  did  not  approve  of  the  practice 
of  giving  an  [emetic,  since  by  the  time  the  dangerous 
symptoms  had  appeared  the  drug  taken  into  the  stomach 
had  been  entirely  absorbed.  If,  however,  there  were 
any  reason  to  suppose  that  such  were  not  the  case,  the 
best  emetic  to  employ  was  apomorphia  given  hypoder- 
mically.  But  red  wine,  he  claims,  is  the  true  and  cer* 
tain  antidote  to  resorcin. —  Wiener  Medizinische  Presse^ 
No.  z^,  1884. 

Minute  Doses  of  Calomel  in  the  Treatment  of 
Pneumonia. — Dr.  Droux  de  Chapois  relates  in  the  Bul- 
letin General  de  Th'erapeutique^  vol.  cviii..  No.  2,  1884, 
several  cases  of  pneumonia  in  which  resolution  was  de- 
layed for  a  very  long  time,  where  an  excellent  result  was 
obtained  by  fractional  doses  of  calomel  (^  grain)  re- 
peated every  hour.  He  advises  a  recourse  being  had  to 
this  treatment  whenever,  despite  the  ordinary  remedies, 
the  symptoms  grow  worse  instead  of  better,  when  the 
tongue  becomes  dry,  and  when  the  skin  imparts  a  sensa- 
tion of  great  heat  and  dryness  to  the  finger.  He  mixes 
one  grain  of  calomel  with  a  teaspoonful  of  powdered 
sugar,  and  after  it  has  been  thoroughly  stirred  for  some 
minutes  divides  it  into  twenty-five  powders.  Within 
twenty  four,  or  at  most  forty-eight  hours,  he  states,  the 
skin  becomes  damp,  the  temperature  falls,  the  tongue 
becomes  moist,  and  the  oppression  diminishes.  Some- 
times a  liquid  stool  occurs  after  fifteen  or  twenty  doses 
have  been  taken ;  when  this  occurs  the  dose  is  reduced  to 
-^  grain  every  hour.  Sometimes  no  stool  occurs,  but 
colicky  pains  are  complained  of.  In  this  case  it  is  not 
necessary  to  withhold  the  drug,  but  only  to  give  a  little 
magnesia  with  it. 

The  Chemical  Poisons  formed  within  the  Intes- 
tinal Canal. — Dr.  Netler  concludes  a  long  review  on  . 
this  subject  as  follows  {Archives  Generates  de  Medecine^ 
October,  1884) :  The  presence  of  inferior  organisms  pro- 
duces, in  the  Course  of  decomposition  of  nitrogenous 
matters,  toxic  substances  of  greater  or  less  activity. 
These  putrid  poisons,  or  ptomaines,  exist  not  6nly  in  putre- 
faction occurring  without  the  body,  but  are  present  also 
normally  in  the  digestive  canal,  and  even  in  the  blood. 
They  play  a  very  important  part  in  pathology,  and  to  them 
may  be  attributed :  i,  poisoning  by  putrefactive  matters, 
in  which  the  poison,  formed  without  the  body,  enters  the 
organism  by  way  of  the  intestinal  canal  or  a  wound  ;  2, 
putrid  auto-intoxication,  due  to  the  action  of  ptomaines 
formed  within  the  digestive  tube  ;  3,  the  r61e  of  these 
ptomaines  is  very  important,  though  at  first  sight  less  evi- 
dentj'^in  uraemia  and  acholia  due  to  changes  in  the  kidneys 
or  liver.  In  these  cases  the  alkaloids,  not  being  excreted 
by  the  diseased  organs,  accumulate  in  the  blood,  and 
give  rise  to  symptoms  of  poisoning.] 


684 


THE   MEDICAL  RECORD. 


[December  20, 1884, 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 

Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  58  Ufayette  Place. 

New  York,  December  20,  1884. 

THE  NEW  HEALTH  BILL  BEFORE  CONGRESS. 

In  a  previous  article  we  called  the  attention  of  the 
American  Public  Health  Association,  then  about  to  as- 
semble in  St.  Louis,  to  the  importance  of  maturing  meas- 
ures thus  early  to  be  adopted  and  enforced  in  the  event 
of  an  epidemic  of  cholera  in  this  country.  The  questions 
which  we  raised  were  as  to  the  best  methods  of  securing 
concert  of  action  of  all  State  and  municipal  boards  of 
health,  and  of  bringing  into  active  co-operation  with 
these  boards  the  General  Government.  The  Association 
gave  these  subjects  due  consideration,  and  adopted  a  re- 
port embodying  a  scheme  of  prevention.  In  regard  to 
cholera,  the  report  advised  the  appointment  and  main- 
tenance of  medical  officers  of  health  at  foreign  ports, 
from  which  cholera  may  be  brought,  whose  duty  it  shall 
be  to  inspect  vessels  bound  to  our  ports,  and  give  the 
requisite  information,  as  to  the  existence  or  appearance 
of  that  disease,  to  the  constituted  authority  in  this 
country ;  a  close  alliance  of  our  health  authorities  with 
those  of  the  Dominion  of  Canada;  the  establishment 
and  support  of  an  inspection  and  quarantine  service,  like 
that  inaugurated  by  the  National  Board  of  Health  ;  aid 
of  local  boards  by  the  General  Government  in  the  ap- 
propriation of  necessary  funds  ;  the  removal  of  local 
unsanitary  conditions  favorable  to  the  development  of 
cholera ;  isolation  of  first  cases  and  destruction  of  in- 
fected materials ;  isolation  of  infected  localities  and 
towns,  and  intercourse  with  other  towns  under  sanitary 
supervision. 

Though  the  scheme  embodies  most  of  the  precautions 
necessary  to  be  taken  to  prevent  a  cholera  epidemic, 
yet  the  plan  lacks  that  continuity  and  coherence  which 
a  body  embracing  the  foremost  sanitary  thinkers  and 
workers  of  the  United  States  ought  to  have  formulated 
With  the  enemy  three  thousand  miles  away,  and  know- 
ing precisely  the  route  and  the  methods  of  its  approach 
and  invasion,'  a  practical  sanitarian  ought  to  be  able  to 
state  positively  what  steps  must  be  taken  to  prevent,  i, 
the  embarkation ;  2,  the  transit ;  and,  3,  the  landing  of 
this  scourge  on  our  shores.  Evidently  the  first,  and  by 
far  the  most  important  duties  in  the  scheme  of  prevention 
must  be  performed  by  the  General  Government,  for  it 
alone  can  regulate  travel  and  traffic  on  the  great  ocean 
highways.  The  Association  should  not  only  have  specifi- 
cally stated  what  those  duties  are,  but  should  have  taken 
measures  to  ensure  the  necessary  action  of  the  Govern- 
ment    Cholera  is  not  to  be  prevented  by  reports  and 


proclamations,  but  by  energetic  work  on  the  part  of  those 
who  are  appointed  to  protect  the  public  health.  To- 
day the  obligation  to  prevent  the  introduction  of  cholera 
into  this  country  rests  solely  with  the  National  Govern- 
ment. No  member  of  the  Association  doubts  that,  if  the 
Government  was  thoroughly  alive  to  its  great  responsi* 
bility  and  exercised  its  full  power  intelligently,  it  could 
prevent  the  importation  of  the  germs  of  this  or  any  other 
foreign  pestilence.  But  will  the  Government  act 
promptly,  wisely,  and  effectively  ?  That  is  the  all-impor- 
tant question  for  the  Association  to  determine,  and  if 
that  body  really  intends  to  do  more  than  put  itself  on 
record  as  proposing  a  few  desultory  and  disconnected 
measures  against  the  invasion  of  cholera,  it  has  an  im- 
mediate and  pressing  duty  to  perform.  It  should  at  once, 
through  a  competent  committee,  bring  its  intelligence 
and  great  influence  to  bear  upon  the  Government,  both 
in  devising  measures  of  prevention  and  aiding  in  their 
execution. 

A  step  has  been  taken  in  the  right  direction  by  the 
State  Boards  of  Health  which,  during  the  past  week, 
held  a  Conference  at  Washington,  reviewed  the  several 
questions  involved  in  the  scheme  of  prevention,  and  con- 
ferred with  members  of  Congress  and  Government  offi- 
cials. This  Conference  did  not,  we  believe,  directly 
represent  the  Association,  but  stood  alone  as  the  repre- 
sentative of  the  State  Boards  of  Health.  The  Association, 
therefore,  has  as  yet  taken  no  active  steps  to  secure  the 
adoption  and  enforcement  of  the  measures  of  prevention 
which  it  recommended  at  St  Louis.  Can  it  afford  to 
remain  idle  during  an  epidemic  of  cholera  with  the  mere 
statement  of  platitudes  ?  We  believe  not.  It  has  the 
necessary  organization,  through  its  executive  and  ad- 
visory committees,  for  immediate  and  aggressive  work, 
and  it  will  sadly  come  short  of  its  duty  and  its  high 
prerogatives  if  it  does  not  become  a  potent  factor  m 
organizing  and  sustaining  measures  of  defence.  In  this 
preliminary  movement  of  the  State  Boards  of  Health,  in 
holding  a  conference  at  Washington,  the  Association 
should  have  been  represented,  in  order  to  aid  in  maturing 
those  plans  which  it  should  co-operate  in  carrying  into 
effect. 

The  Conference  of  State  Boards  found  an  anomalous 
condition  of  affairs  at  Washington,  and  sought  to  remedy 
it  by  preparing  a  bill  to  be  submitted  to  Congress. 
This  bill  provides  for  the  organization  of  a  National 
Board  of  Health,  to  be  composed  of  one  representative 
from  each  existing  State  Board  of  Health.  The  re- 
maining provisions  of  the  biU  are  designed  to  render 
the  board  the  efficient  agent  of  the  Government  in 
the  prevention  of  epidemics.  The  purposes  of  the  Con- 
ference are  good  and  commendable,  though  perhaps 
the  objects  sought  might  have  been  obtained  more  di- 
rectly and  immediately.  Certainly  we  need — nay,  must 
have — a  National  Board  of  Health  competent  to  employ 
wisely  and  efficiently  the  powers  of  the  General  Govern- 
ment in  the  protection  of  the  public  health.  But  those 
who  seek  such  legislation  as  the  Conference  contem- 
plates should  be  well  advised  of  the  obstacles  in  their 
way,  and  the  nature  of  the  opposition  which  they  will 
meet.  There  is  already  a  National  Board  of  Healthy 
fully  organized  and  equipped  to  perform  all  the  functions 
which  thi»  bill  imposes  upon  a  new  board.     Let  the  Con- 


December  20,  1884.] 


THE   MEDICAL  RECORD. 


685 


ference  inquire  into  the  history  of  the  defeat  of  this  board 
and  it  will  discover  an  agent  in  the  Treasury  Department 
hostile  to  all  further  health  legislation,  unless  such  legis- 
lation places  under  his  control  the  public  funds,  appro- 
priated for  sanitary  purposes.  We  refer  to  the  chief 
medical  officer  of  the  Marine  Hospital  Service.  To  this 
source  must  be  referred  whatever  miscarriage  there  has 
been  of  proper  support  of  the  existing  board  by  Con- 
gress, and  it  is  from  this  source  will  come  the  secret 
influences  which  will  tend  powerfully  to  defeat  all  proper 
health  legislation  during  the  present  session.  In  under- 
taking, therefore,  to  secure  the  favorable  action  of  Con- 
gress on  its  bill  the  Conference  must  be  prepared  to  en- 
counter and  overcome  the  opposition  which  a  bureau, 
already  in  possession  by  artful  intrigues  of  the  funds  and 
the  power  belonging  to  the  existing  board,  can  wield 
through  the  Treasury  Department. 


MORPHINISM    DETECTED   THROUGH  THE   EXAMINA- 
TION OF  THE  URINE. 

MoRPHioMANiA  has  been  growing  so  rapidly  and  withal 
so  quietly  in  our  country  that  its  present  proportions  are 
hardly  realized,  even  by  the  profession.  It  is  not  alone 
to  the  specialist,  nor  to  the  physician  who  has  a  home 
and  a  method  for  the  cure  of  the  opium-habit  that  the 
subject  is  of  interest,  the  general  practitioner  may  at 
any  moment  meet  with  cases  of  a  more  or  less  pro- 
nounced character. 

The  ruses  resorted  to  by  many  patients  to  obtain  their 
favorite  drug,  and  the  great  facilities  they  have  of  secret 
indulgence,  tend  at  times  to  mislead  and  render  treat- 
ment unsatisfactory. 

Again,  in  the  therapy  of  ordinary  diseases  in  mor- 
phine takers,  our  remedies  may  be  counteracted  or  their 
effects  modified  to  an  extent  incompatible  with  recovery. 
It  may  become  important  for  us  to  discover,  therefore,  if 
the  drug  is  being  taken  surreptitiously. 

It  has  been  claimed  by  many  that  morphia  becomes 
so  changed  in  the  system  that  no  traces  of  the  alkaloid, 
as  such,  are  to  be  found  in  the  tissues  or  excretions.  On 
the  other  hand,  several  observers  hold  an  opposite  view. 
On  account  of  the  diversity  of  opinion  in  competent  ob- 
servers and  the  practical  significance  of  the  entire  sub- 
ject. Dr.  Notta  has  made  some  careful  investigations, 
touching  the  elimination  of  morphia  by  the  kidneys.  He 
has  published  the  results  of  his  research  in  L' Union 
Midicale.  At  first  he  used  Mayer's  test,  by  the  double 
iodide  of  potassium  and  mercury,  then  that  of  Bou- 
chardat.  Both  of  these  proved  unsatisfactory,  giving 
positive  results  only  where  the  daily  quantity  of  urine 
was  small. 

Thus,  Mayer's  test  gave  a  characteristic  precipitate 
only  when  each  quart  of  urine  contained  at  least  three 
grains  of  the  alkaloid.  Bouchardat's  test  gave  reliable 
results  when  as  little  as  one  to  two  grains  were  present. 

The  author's  own  method,  which  he  recommends  as 
simple,  exact,  and  rapid,  is  as  follows : 

Treat  a  quart  of  the  suspected  urine  with  subacetate  of 
lead  (i  to  10).  The  precipitate  is  a  combination  of  the 
lead  with  the  uric,  phosphoric,  and  other  acids  existing 
in  the  urine  and  the  coloring  matters  and  the  extrac- 
tives. 


The  decolorized  urine  then  contains  the  morphine 
combined  with  acetic  acid,  the  substances  not  precipitable 
by  the  sub-acetate  of  lead,  and  the  excess  of  the  lead.  Now 
filter  and  get  rid  of  the  lead  by  adding  sulphuric  acid 
(i  to  10),  drop  by  drop  until  there  is  no  further  precipi- 
tate. Filter  again,  add  an  excess  of  ammonia  and  warm 
amylic  alcohol  and  shake.  The  mixture  soon  becomes 
clear  and  holds  in  solution  all  the  morphine  previously  in 
the  urine.  After  this  it  is  only  necessary  to  shake  this 
solution  with  water  acidulated  with  sulphuric  acid  in  or- 
der to  obtain  the  morphia  as  a  sulphate.  This  is  decom- 
posed with  ammonia  water  and  taken  up  again  with  amy- 
lic alcohol,  and  after  evaporation  we  have  the  morphine, 
which  can  be  tested  with  the  usual  tests. 

The  conclusions  which  Notta  draws  from  his  investiga- 
tions are :  that  morphine  is  eliminated,  in  great  part  at 
least,  by  the  kidneys,  provided  they  are  not  diseased ; 
that  Mayer's  or  Bouchardat's  tests  can  be  employed  after 
eliminating  sugar  and  albumen,  but  that  when  these  tests 
fail,  the  one  here  given,  or  some  equally  reliable  one 
must  be  employed.  That  it  is  always  possible  to  find 
the  drug  in  the  urine  of  an  habitual  morphine  taker  pro- 
vided as  much  as  i  J  grain  is  taken  per  day. 

Further  experiments  must  be  made  to  decide  whether 
this  test  discovers  morphine  in  such  cases  as  acute  poi- 
soning, or  if  it  is  only  reliable  in  such  cases  as  were  here 
tested,  where  the  drug  had  been  taken  for  a  long  time  in 
large  quantities. 

THE    COLLECTIVE    INVESTIGATION    RECORD  OF   THE 
BRITISH  MEDICAL  ASSOCIATION. 

The  Bristol  Medico-chirurgical  Journal  is  not  satisfied 
with  the  labors  so  far  published  by  the  British  Collective 
Investigation  Committee,  and  takes  the  promoters  of  the 
scheme  severely  to  task.  It  makes  some  remarks,  which 
strike  us  as  being  decidedly  forcible,  even  if  not  alto- 
gether merited. 

Referring  to  the  second  volume  of  this  committee, 
which  deals  principally  with  pneumonia,  and  which  has 
been  previously  noticed  in  our  columns,  it  says  : 

**  Probably  no  scheme  for  the  advancement  of  medical 
science  was  ever  started  under  more  favorable  auspices 
than  this  collective  investigation  one  of  the  British  Medi- 
cal Association.  Prominent  leaders  in  the  profession 
praised  and  promoted  it  on  platform,  paper,  and  com- 
mittee in  the  metropolis;  and  emissaries  of  accredited 
talent  and  eloquence  were  sent  into  the  provinces  to 
preach  to  us  this  new  gospel  of  scientific  research.  Every- 
where their  doctrines  have  been  received  with  a  chorus 
of  assent.  Questions  in  scientific  medicine  were  to  be 
answered  by  the  overwhelming  mass,  and  not  by  the  un- 
supported individual ;  the  untrustworthiness  of  individual 
labors  in  the  closet  was  to  be  replaced  by  the  generalized 
experiences  of  the  practitioner  in  public  ;  and  the  grop- 
ing investigations  of  the  medical  theorist  were  to  be  sup- 
plemented, or  rather  replaced,  by  the  accurate  records 
of  the  practical  worker,  as  figures,  facts,  and  statistics. 
Parturiuni  monies^  nasceiur — let  us  see  what." 

The  Journal  then  shows  that  from  the  sum  expended 
by  the  Association  they  had  aright  to  expect  some  note- 
worthy contribution  to  medical  knowledge.  It  then  con- 
tinues as  follows : 

'^  We  have  systematized  for  us,  under  various  headings, 


686 


THE   MEDICAL  ^RECORD. 


[December  20, 1884. 


the  reports  of  1,065  cases.  The  first  thing  one  naturally 
turns  to  is  the  trustworthiness  of  the  reporters.  The 
men  who  are  most  likely  to  give  us  satisfactory  answers 
to  the  queries  propounded  are  the  various  teachers  in 
our  medical  schools,  the  physicians  to  our  hospitals,  the 
men  whom,  in  consultation  or  general  practice;  we  know 
to  have  most  experience  of  the  complaint  and  most 
knowledge  of  it  We  have  gone  carefully  over  the  names 
of  those  who  have  made  the  returns,  and  we  have  dis- 
covered among  them  scarcely  one  which,  either  from 
general  reputation  in  these  islands  or  from  local  reputa- 
tion in  our  own  district,  deserves  to  be  heard  as  of  any 
authority.  That  our  hospital  and  consulting  physicians 
practically  ignore  these  inquisitive  cards  there  can  be  no 
doubt.  The  fact  is  patent  to  any  one  who  looks.  These 
are  the  men  who  see  most  of  the  disease,  and  know  most 
of  the  subject,  and  who  are  most  competent  to  give  re- 
turns. Why  do  they  ignore  the  queries  ?  Do  they  dis- 
trust the  process  ?  We  fear  there  is  no  other  explanation 
possible.  To  begin  with,  therefore,  it  submits  that  those 
most  competent  to  answer  refuse  to  do  so,  and  the  trust- 
worthiness of  the  report  is  thus,  in  the  first  place,  weak- 
ened.*' 

The  practical  outcome  of  the  replies  of  all  these 
practitioners,  in  the  writer's  own  words,  is  this :  **  It  is 
manifest  that  the  lines  of  treatment  are  so  various  as  not 
to  permit  of  any  value  being  attached  to  a  comparison 
of  mortality.  Surely  this  is  the  classical  mouse  of  the 
mountains  in  travail  at  last ! " 

In  conclusion,  the  Journal  thinks  that  polling  impres- 
sions of  its  practitioners  is  not  the  way  to  promote 
science.  "  The  variables  and  contingencies  are  so  numer- 
ous and  so  important  that  they  cannot,  as  in  this  instance, 
be  ignored.  To  ignore  these  is  to  nullify  the  whole  work. 
And  even  if  the  results  of  this  questioning  were  to  be 
quite  trustworthy,  drawn  up,  criticised^  ana  tabulated 
by  skilled  observers,  we  fail  to  see  what  new  truth  this 
galloping  over  the  surface  of  disease  can  bring  forth.  We 
have  been  galloping  over  disease  for  centuries,  and  the 
outcomes  are  abundant  enough  in  myriads  of  works  in  a 
score  of  languages.  We  want  nowadays  to  attack  dis- 
ease from  the  bottom.  The  work  must  be  one  of  con- 
centrated labor  by  the  most  penetrating  intellects,  with 
every  opportunity  to  study  disease  at  the  bedside  and  in 
the  laboratory,  and  not  of  vague  recollections  jotted 
down  in  the  midst  of  other  pursuits  by  the  rank  and  file, 
and  huddled  into  columns  by  committees.  No  doubt  the 
Collective  Investigation  Committee  will  soon  come  to  a 
natural  and  timely  end ;  in  the  meantime  we  would  ex- 
press our  regret  that  so  much  money  of  the  British  Medi- 
cal Association,  which  might  go  to  its  excellent  benevo- 
lent fund,  should  be  expended  on  an  undertaking  so 
palpably  useless  as  this  one." 


PRECOCIOUS  CANCER  OF  THE  STOMACH. 

The  difficulties  that  at  times  surround  the  diagnosis  of  can- 
cer of  the  stomach  are  well  known.  When  the  symptoms 
are  indistinct  and  the  physical  exploration  unsatisfactory, 
cancer  is  sometimes  excluded  on  account  of  the  youth  of 
the  individual.  For  by  common  consent  carcinoma  of  the 
stomach  is  regarded  as  of  rare  occurrence  before  the  age 
of  forty.     Yet  we  are  often  enough  surprised  to  find  at  an 


autopsy  a  gastric  cancer,  where  no  suspicion  of  the  dis- 
ease existed  during  the  lifetime  of  the  patient 

Dr.  Mathieu,  of  Lyon,  has  recently  made  a  special 
study  of  carcinoma  of  the  stomach,  as  it  occurs  early  in 
life. 

From  the  literature  of  the  subject  he  has  collected 
twenty-seven  cases,  most  of  which  were  observed  before 
the  age  of  thirty.  The  author  separates  them  into  three 
groups. 

The  first  comprises  those  cases  in  which  a  diagnosis 
was  made  of  some  entirely  different  disease.  This  hap- 
pened  nine  times.  The  diagnosis  of  cirrhosis  being  made 
five  times,  cancer  of  the  liver,  aneurism  of  the  aorta, 
tumor  of  the  spleen,  and  pleurisy,  each  once. 

The  second  group  contains  eight  cases.  Here  the 
difficulty  was  located  in  the  digestive  tract,  its  cancerous 
nature,  ( however,  not  being  recognized.  Pregnancy 
existed  in  four  of  the  patients  belonging  to  this  group, 
and  the  persistent  vomiting  was  regarded  as  that  common 
to  their  condition.  Only  one  patient  had  hamatemesis, 
which  came  on  shortly  before  death.  The  disease  was 
put  down  as  dyspepsia  in  one  case,  and  in  another  as 
ulcer  of  the  stomach. 

The  third  group  finally  includes  those  cases  in  which  a 
correct  diagnosis  was  reached,  the  tumor  being  made  out 
in  every  instance.  It  would  appear,  therefore,  that  two- 
thirds  of  these  cases  passed  unrecognized,  and  were  mis- 
taken for  diseases  that  had  no  connection  with  the  diges- 
tive tract.  The  course  of  gastric  cancer  of  early  life  is, 
according  to  Mathieu,  rapidly  fatal,  characteristic  cachexia 
is  commonly  absent,  and  haematemesis  quite  rare.  It 
seems,  therefore,  that  the  disease  does  not  fully  confonn 
to  the  usual  type  of  cancer,  as  ordinarily  seen  later  in 
life.  

THE  CLINICAL  FORMS  OF  HEPATIC  COLIC. 
Among  the  painful  affections  of  the  abdominal  viscera 
few  are  more  distressing,  and  oftentimes  difficult  to  re- 
lieve, than  the  various  forms  of  hepatic  colic. 

Dr.  Olive,  of  Paris,  has  recently  made  a  study  of  he- 
patic colic,  from  a  purely  clinical  standpoint,  a  review 
of  which  is  published  in  the  Journal  de  M/decinCy  Octo- 
ber 18,  1884.  Among  the  principal  causes  of  hepatic 
colic  he  finds  arthritism,  with  its  various  manifestations, 
such  as  obesity,  diabetes,  and  calculus ;  forced  repose, 
sadness,  sedentary  occupations,  abuse  of  alcohol,  a  diet  • 
too  exclusively  animal  or  fatty,  and  different  chronic 
affections  of  the  liver  also  invite  colic 

The  immediate  determining  causes  are  those  which 
produce  violent  jars  to  the  abdominal  organs,  such  as 
horseback  riding,  the  jolting  of  vehicles,  and  the  like. 

The  author  describes  a  form  of  colic  which  he  tenns 
pseudo-gastralgic-hepatic  colic,  which  he  dififerentiaies 
firom  gastralgia  by  the  following  characteristics  : 

The  patient  suffering  from  gastralgia  has  more  frequent 
pains,  and  would  not  go  for  three  or  four  months  without 
suffering,  as  the  pseudo-gastralgic  patient  often  does^ 
Gastralgia  causes  distress  when  the  stomach  is  empty, 
and  at  or  just  after  a  meal.  The  time  for  pseudo-gas- 
tralgia  to  appear  is  usually  about  two  hours  after  eating. 

The  pains  come  on  suddenly  in  hepatic  colic,  less  so 
in  gastralgia.  They  radiate  toward  the  shoulder  m  h^ 
patic  colic,  but  not  in  gastralgia. 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


687 


Still  there  may  be  a  reflex  intercostal  neuralgia  accom- 
panying the  latter  affection.  After  hepatic  colic,  even 
without  icterus,  the  urine  is  commonly  red,  and  contains 
biliaiy  pigment.  This  is  never  the  case  in  gastralgia 
pure  and  simple. 

FURTHER  PATHOLOGICAL  AND  THERAPEUTICAL  CON- 
TRIBUTIONS  TO  CHOLERA. 

•     The  number  of  contributions  to  the  subject  of  cholera 

is  increasing  rather  faster  than  they  can  be  recorded. 

Professor  B.  Grassi,  in  the  Gazz.  degli  Ospitali,  states 

that  he  has  found  the  comma^baciUi  in  the  stools  of  per- 

sons  suffering  from  choleraic  diarrhcea,  or  cholerine.   The 

patient  whose  dejecta  was  examined  was  a  soldier  in  a 

regiment  of  which  some  members  had  been  attacked  with 

cholera.     Professor  Grassi,  together  with  Drs.  Vivanti 

and  Berretta,  added  to  the  number  of  bacilli  repasts  by 

swallowing  dried  cholera-bacilli     They  experienced  no 

ill  effects.     Professor  Grassi  believes  that  flies  are  active 

and  important  agents  in  spreading  cholera.     Professor 

Cantani,  in  the  same  journal,  reports  the  results  of  some 

oi  his  examinations  of  the  blood  in  cholera  patients. 

He  finds  that  with  the  progress  of  the  disease  the  blood 

lessens  in  alkalinity  and  finally  at  death  is  actually  acid. 

He  infers  from  this  fact  (which  was  known  before)  that 

if  venous  injections  be  made  in  treating  the  disease  the 

Hquid  used  ought  to  be  more  alkaline  than  that  hitherto 

employed. 

Dr.  Manfredi  has  studied  the  action  of  tannic  acid  upon 
cholera-bacilli  and  finds  that  even  in  small  amounts,  it 
kills  them.  He  therefore  recommends  the  rectal  injec- 
tion of  solutions  of  this  drug.  Cantani  recommends  the 
same  method  and  gives  the  following  formula  : 

I*.  Aq.  catid 2000 grammes. 

Acid,  tannic 5-6-10         " 

Gum  arab ^o         " 

,^     '^''•^P" 3o-5ogtt 

Professor  Alberta  Riva,  as  the  result  of  experiments 
upon  animals,  thinks  that  saline  injections  made  into  the 
pleural  cavity,  or  preferably  into  the  peritoneal  cavity, 
may  be  beneficial  in  cholera. 

Dr.  Panier,  in  El  Sigh  Medico,  recommends  the  heroic 
use  of  strychnine  throughout  the  whole  course  of  cholera. 
He  gives  hourly  about  gr.  ^  of  sulphate  of  strychnia. 
MM.  Huchard  and  Dujardin-Beaumetz  recommend  the 
hypodermic  injection  of  caffeine  dissolved  in  a  solution 
of  benzoate  of  soda.     The  dose  given  is  about  gr.  jss. 

ILe  JProgres  Medicale  quotes  the  results  of  the  treatr 
ment  of  cholera  with  injections  of  chloral  hydrate  by  Dr. 
Reddi6,  of  Partabgark,  India.  He  employed  injections 
of  small  doses  of  chloral  hydrate.  Thirty-five  per  cent. 
oi  his  cases  died,  while  under  other  treatment  the  mortal- 
ity was  sixty-four  per  cent. 


The  Last  New  Antipyrktic  is  thallin,  and  it  has 
been  introduced  by  Dr.  V.  Jaksch,  of  Vienna.  It  is  one 
of  the  chinolin  compounds,  and  is  a  powerful  antifermen- 
tative.  Jaksch  has  used  it  in  eighty-suc  cases,  and  found 
that,  although  a  powerful  antipyretic,  it  is  by  no  means  a 
specific. 


^jextTB  xvf  ttce  ^SK^^K 


The  Biologigal  Department  of  the  University  of 
Pennsylvania  was  formally  opened  on  the  4th  instant 
by  Provost  William  Pepper.  Addresses  were  made  by 
Drs.  Harrison  Allen  and  Joseph  Leidy. 

The  State  Board  of  Lunacy  of  Pennsylvania 
have  been  diligently  investigating  the  condition  of  the 
State  Asylums  since  August  last.  As  a  result,  says  the 
Medical  Times,  they  have  been  able  to  report  to  the 
State  Board  eighteen  cases  of  alleged  improper  treatment 
which  they  had  investigated,  in  some  of  which  gross  neg- 
lect and  wanton  cruelty  had  been  practised.  Several  of 
these  have  been  already  removed  to  State  hospitals,  and 
new  cases  are  constantly  coming  to  light. 

Death  o^  Dr.  Henry  Gibbons. — We  regret  to  an- 
nounce the  death  of  Dr.  Henry  Gibbons,  of  San  Fran- 
cisco, CaL,  in  the  seventy-sixth  year  of  his  age.  Dr. 
Gibbons  was  born  in  Wilmington,  Del.  He  graduated 
in  medicine  from  the  University  of  Pennsylvania,  in  1829. 
In  1850  he  moved  to  San  Francisco.  He  established 
and  successfully  conducted  the  Pacific  Medical  and  Sur- 
gical Journal,  He  was  also  one  of  the  founders  of  and 
teachers  in  the  Medical  College  of  the  Pacific.  He  was 
a  member  of  the  Society  of  Friends. 

The  Bacillus  of  Syphilis. — Dr.  Sigmund  Lustgarten, 
describes  a  "  specific  bacillus  of  syphilis  "  (  Wiener  Medi- 
cin.  Wbchen.,  No.  47,  1884)  which  he  has  discovered  in 
the  initial  lesions  and  in  gummata  of  syphilis.  It  is 
of  about  the  same  size  and  appearance  as  the  tubercle 
bacillus  and  lies  in  small  groups  enclosed  in  the  some- 
what swollen  lymphoid  cells.  The  organism  is  distin- 
guished from  other  bacilli  by  its  staining  and  peculiar 
grouping.  The  investigations  of  previous  discoverers  of 
syphilis-germs  are  characterized  as  being  "  tinctured  with 
grave  errors." 

The  Death  of  Dr.  James  G.  Thomas,  of  Savannah, 
Ga.,  recently  occurred  under  unusually  painlul  cir- 
cumstances. Dr.  Thomas  was  a  member  of  the  Execu- 
tive Committee  of  the  Ninth  International  Congress. 
He  took  a  deep  interest  in  the  success  of  the  Congress, 
and,  at  a  considerable  sacrifice,  came  to  Washington, 
November  29th,  to  attend  the  meeting  for  organization. 
While  on  the  way  he  was  seized  with  a  violent  chill,  and 
on  his  arrival  at  once  took  to  his  bed,  from  which  he 
never  again  arose,  the  disease  proving  to  be  acute  lobar 
pneumonia.  He  may  be  said  to  have  lost  his  life  in  the 
service  of  the  Congress,  and  it  is  an  irreparable  loss  to  the 
Executive  Committee,  as  well  as  to  his  bereaved  family 
and  his  fellow-citizens  oi  Savannah  and  of  Georgia. 

Importation  of  Rags. — The  Treasury  Department 
has  decided  that  no  old  rags  shall  be  landed  in  th^  United 
States  except  upon  disinfection  by  one  of  the  following 
processes :  i.  Boiling  in  water  for  two  hours  under  a 
pressure  of  fifty  pounds  per  square  inch.  2.  Boiling  in 
water  for  four  hours  without  pressure.  3.  Subjection  to 
the  action  of  confined  sulphurous-acid  gas  for  six  hours, 
burning  one  and  a  half  or  two  pounds  roll  brimstone  in 
each  1,000  cubic  feet  of  space,  with  the  rags  well  scat- 
tered upon  racks.    4.  Disinfection  in  the  bale  by  means 


688 


THE  MEDICAL  RECORD. 


[December  20,  1884. 


of  perforated  screws  or  tubes  through  which  sulphur 
dioxide,  or  superheated  steam  at  a  temperature  of  not 
less  than  350  degrees,  shall  be  forced  under  a  pressure 
of  four  atmospheres  for  a  period  sufficient  to  insure 
thorough  disinfection. 

The  Presbyterian  Hospital. — A  lady  has  promised 
to  give  $50,000  to  the  Presbyterian  Hospital  for  the 
purpose  of  erecting  a  new  wing,  provided  an  equal  sum 
is  raised  by  other  parties. 

Trained  Nurses  for  the  Insane. — A  special  com- 
mittee of  the  State  Charities  Aid  Association  has  pre- 
pared a  report  upon  the  training  of  nurses  for  the  in- 
sane. The  committee  has  secured  the  co-operation  of 
the  Bellevue  Training  School,  and  is  now  occupied  in 
maturing  a  plan  by  which  a  certain  number  of  women 
trained  there  as  nurses  for  the  sick  may  secure  in  one  of 
our  lunatic  asylums  a  special  training  in  the  care  of  the 
insane. 

Deaths  of  Foreign  Medical  Men. — The  past  few 
weeks  has  witnessed  the  death  of  a  number  of  prominent 
European  medical  men.  In  France  we  have  chronicled 
the  death  of  M.  Fauvel,  the  distinguished  Vice-president 
of  the  Acad6mie  de  M6decine.  We  learn  that  Professor 
Fonssagrives,  of  the  Montpellier  Faculty  of  Medicine  has 
recently  died  of  cholera.  In  Germany,  the  deaths  are 
announced  of  Professor  v.  Wittich,  of  Konigsberg,  and 
Professor  K.  v.  Vierordt,  of  Tubingen.  Professor  Kolbe» 
of  Leipzig,  and  Professor  Chvostek,  of  Vienna,  also  re- 
cently died. 

Medical  Diplomas  in  Australia.— A  physician  of 
Pictou,  N.  S.  W.,  has  been  refused  a  license  to  practise 
because,  although  he  had  a  degree  of  M.D.,  granted  by 
the  University  of  Philadelphia^  yet  it  only  certified  to  his 
studying  for  three  years.  The  authorities  as  well  as  the 
medical  journals  make  the  mistake  of  thinking  that  the 
degree  and  the  University  are  all  right. 

Gift  TO  A  German  Hospital. — The  German  Hospital 
of  Philadelphia  has  recently  been  enlarged  and  greatly 
improved.  The  sum  of  $600,000,  which  covers  the  ex- 
pense of  the  changes,  was  given  to  the  hospital  by  Mr. 
John  D.  Lakenau,  President  of  the  Board  of  Trustees. 

Hayem's  Formula  for  Intra- Venous  Injection  in 
Cholera  : 

Aquae  distillat i  litre. 

Sodii  chlorid.   pur 5  grammes. 

Sodii  sulphat.  pur 10  grammes. 

M.  Filter  and  give  two  to  two  and  a  half  litres  at  a  tem- 
perature of  38°  C.  The  time  occupied  in  giving  is  twelve 
to  fifteen  minutes. 

Dr.  Louis  H.  Steiner  has  just  been  elected  librarian 
of  the  new  Pratt  Free  Library  in  Baltimore,  which  has 
been  completed  at  a  cost  of  $1,000,000. 

Death  During  a  Foot-ball  Match. — Another  death 
is  recorded  as  occurring  at  a  foot-ball  match  between  stu- 
dents of  St.  Thomas'  Hospital,  London.  The  victim  was  a 
young  man,  aged  twenty-three,  who,  while  in  the  midst  of 
the  game,  suddenly  staggered  and  fell  down  dead. 

The  Rabbeth  Memorial. — A  thousand  dollars  have 
ab-eady  been  collected  for  this  purpose. 


Dr.  Jay  Owens  retires  from  the  editorship  of  the 
Northwestern  Lancet,  He  is  succeeded  by  Dr.  C.  B. 
Witherle. 

The  Loneliest  Doctor  in  the  World  is  the 
ophthalmologist  who  hasn't  written  an  article  on  co- 
caine. 

The  Use  of  Iodide  of  Potassium  in  Large  Doses. 
—Dr.  W.  C.  Dabney,  of  Charlottesville,  Va.,  calls  our 
attention  to  a  clinical  lecture  by  Charcot,  published  in 
Le  Progrh  M^ical  for  January  13,  1877,  and  showing 
that  Charcot  had  used  potassium  iodide  in  doses  of  six  to 
ten  grammes  daily  since  1874. 

Ovariotomy  in  Rome. — Dr.  J.  H.  Thompson,  of 
Rome,  Italy,  sends  us  the  records  of  a  case  of  ovariot- 
omy performed  by  himself  recently,  and  regarding  which 
there  were  several  points  of  more  than  ordinary  interest. 
He  writes  :  "  Ovariotomy  in  Rome  has  generally  been 
unsuccessful,  I  think  owing  to  the  fact  that  it  has  mostly 
been  performed  in  hospitals  which  were  built  in  the 
fifteenth  century  (persons  who  had  the  ability  to  pay  for 
home  attention  generally  preferring  to  go  to  London). 
These  old  buildings  cannot  be  made  aseptic."  This 
case  was  operated  upon  in  a  specially  provided  apart- 
ment. It  was  complicated  with  pregnancy-  We  regret 
that  the  report  is  too  long  for  publication  by  us. 


THE  TEXT  OF  THE  NEW  HEALTH  BILL. 

The  following  is  the  text  of  the  new  Health  Bill,  pre- 
pared by  the  National  Conference  of  State  Boards  of 
Health,  now  before  Congress  : 

To  amend  an  Act  entitled  "An  Act  to  prevent  the 
introduction  of  contagious  and  infectious  diseases  into 
the  United  States  and  to  establish  a  National  Board  of 
Health." 

Be  it  enacted  by  the  Senate  and  House  of  Representa- 
tives of  the  United  States  of  America  in  Congress  assem- 
bled.  That  an  Act  entitled,  "  An  Act  to  prevent  the  in- 
troduction of  contagious  and  infectious  diseases  into  the 
United  States  and  to  establish  a  National  Board  of 
Health,"  approved  March  3,  1879,  t>e  so  amended  as 
to  provide  that  there  shall  be  established  a  National 
Board  of  Health,  to  consist  of  one  member  from  each 
State  Board  of  Health  now  established,  or  which  may  be 
hereafter  established  in  the  United  States,  to  be  appointed 
by  the  President  and  confirmed  by  the  Senate,  whose 
compensation,  when  actually  engaged  in  the  performance 
of  duty  under  this  act,  shall  be  ten  dollars  per  diem  each, 
and  reasonable  expenses.  This  board  shall  meet  in 
Washington  within  ninety  days  after  the  passage  of  this 
Act,  and  shall  meet  in  Washington  annually,  and  in  case 
of  emergency  upon  the  call  of  its  chairman  and  secretary, 
or  upon  the  extraordinary  call  of  the  President  of  the 
United  States,  as  hereinafter  provided. 

The  officers  of  this  board  shall  be  a  chairman  and 
secretary.  The  secretary  shall  be  the  executive  officer 
of  and  ex-officio  a  member  of  the  board,  and  shall  devote 
his  entire  time  to  the  duties  of  the  office,  and  may  be  re- 
moved for  cause,  at  any  regular  meeting  of  the  board, 
two-thirds  of  the  full  board  voting  therefor,  and  shall  re- 
ceive such  salary  as  may  be  determined  by  the  board. 
The  chairman  with  six  other  members,  representing  the 
various  geographical  divisions  of  the  country,  shall  con- 
stitute the  executive  committee  of  the  board,  to  be  elected 
at  the  first  meeting  of  the  board,  and  at  each  annual 
meeting  thereafter,  and  said  committee  shall,  and  is  here- 
by authorized  to  exercise  such  powers  as  may  from  time 
to  time  be  conferred  upon  it  by  the  board. 

Section  2.  The  duties  of  this  board  shall  be,  and  ft  is 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


689 


hereby  authorized  and  given  power  to  make  or  cause  to 
be  made,  such  investigations  at  any  place  within  the 
United  States,  or  at  any  foreign  port  or  place,  and  to 
collect  information  upon  all  matters  relating  to  the  public 
health,  and  to  frame  such  rules  and  regulations  as  may 
be  necessary  for  the  government  of  the  quarantine  service 
of  the  United  States ;  and  all  the  power  and  authority 
now  provided  by  law,  or  which  may  be  provided  by  law, 
for  the  control  and  protection  of  the  public  health  of  the 
United  States,  shall  be  and  are  hereby  vested  in  said 
board,  except  as  to  the  special  authority  vested  in  the 
President  of  the  United  States  under  the  provisions  of 
this  act.  The  rules  and  regulations  of  this  board  shall 
severally  be  executed,  under  the  direction  of  this  board, 
through  such  Departments  of  the  Government,  or  other 
officers,  as  the  law  may  prescribe  or  the  President  may 
designate. 

This  board  shall  co-operate  with,  and  so  far  as  it  law- 
fully may,  shall  aid  State  and  local  boards  of  health  in 
the  enforcement  of  the  rules  and  regulations  of  such 
boards,  to  prevent  the  entroduction  of  contagious  and  in- 
fectious diseases  from  foreign  countries  into  the  United 
States,  and  into  one  State  from  another. 

Section  3.  It  shall  be  the  duty  of  this  board  to  make 
such  rules  and  regulations  as  are  necessary  to  be  observed 
by  vessels  at  ports  of  departure,  where  such  vessels  sail 
from  any  foreign  port  or  place  to  any  port  or  place  in 
the  United  States,  to  secure  the  best  sanitary  condition  of 
such  vessel,  her  cargo,  passengers,  and  crew,  and  to  pre- 
pare from  time  to  time  for  the  consular  officers  of  the 
United  States,  and  for  the  medical  officers  serving  under 
this  act  at  any  foreign  port,  and  otherwise  make  publicly 
known  such  rules  and  regulations,  which,  when  approved 
by  the  President  and  issued  by  the  Department  of  State, 
and  posted  in  the  office  of  the  consul  or  other  representa- 
tives [of*  the  United  States  at  such  foreign  ports  for  at 
least  ten  days,  shall  be  enforced  by  the  consular  officers 
and  agents  of  the  United  States. 

Section  4.  It  shall  be  unlawful  for  any  vessel  from 
any  foreign  port  or  place  to  enter  any  port  in  the  United 
States,  except  in  accordance  with  the  rules  and  regula- 
tions made  in  pursuance  of  this  act,  and  of  the  rules  and 
regulations  made  under  State  or  municipal  authority,  and 
any  such  vessel  which  shall  attempt  to  enter  any  port  of 
the  United  States  in  violation  thereof,  shall  be  liable  to 
process  in  the  proper  district  court  of  the  United  States, 
and  upon  conviction,  shall  forfeit  to  the  United  States  a 
sum  to  be  awarded  in  the  discretion  of  the  court,  not  ex- 
ceeding $1,000,  which  shall  be  a  lien  upon  such  vessel, 
to  be  recovered  upon  proceeding  in  the  proper  district 
court  of  the  United  States,  in  accordance  with  the  rules 
and  laws  governing  cases  of  seizure  of  vessels  for  viola- 
tion of  the  revenue  laws,  and  in  all  such  cases  the  United 
States  Attorney  for  such  district  shall  appear  on  behalf  of 
the  United  States ;  and  all  such  vessels  shall  obtain  from 
the  consular  or  authorized  medical  officer  at  the  port  of 
departure  a  certificate  in  duplicate,  setting  forth  the 
sanitary  history  of  said  vessel,  and  that  it  has  in  all  re- 
spects complied  with  the  rules  and  regulations  of  this 
board,  made  in  pursuance  of  this  act  for  the  government 
of  such  vessels,  and  before  granting  such  certificate  such 
consular  or  medical  officer  is  required  to  be  satisfied  that 
the  statements  therein  made  are  true;  and  upon  the  re- 
quest of  this  board,  the  President  of  the  United  States  is 
hereby  authorized  to  appoint  proper  medical  officers,  to 
serve  in  the  offices  of  the  consuls  at  any  such  foreign 
ports,  to  make  the  inspections  and  give  the  certificates 
herein  required. 

Section  5.  Such  vessels  shall  observe  all  rules  and 
regulations  made  by  this  board  in  pursuance  of  this  act, 
in  regard  to  the  inspection,  disinfection,  and  isolation  of 
the  same,  upon  its  arrival  at  any  port  in  the  United  States, 
2ind  for  the  treatment  of  persons  and  cargo  on  board,  so 
SLS  to  prevent  the  introduction  of  contagious  diseases  into 
*he  United  States,  and  it  shall  be  unlawful  for  any  vessel 
to  enter  such  port,  to  land  its  passengers  or  discharge  its 


cargo,  except  upon  a  certificate  from  the  health  officer  of 
such  port,  that  such  rules  and  regulations  have  in  all  re- 
spects been  complied  with. 

Section  6.  In  the  event  of  any  sudden  emergency, 
threatening  the  importation  of  contagious  or  infectious 
disease  into  the  United  States  from  any  foreign  country, 
the  President  of  the  United  States  is  hereby  authorized 
and  required,  in  his  discretion,  to  adopt  and  make  known 
forthwith  by  public  proclamation,  such  measures  as  may 
meet  the  emergency,  cither  by  suspending  the  introduc- 
tion into  the  United  States  by  land  or  sea,  of  any  specific 
merchandise  calculated  to  be  a  vehicle  for  the  communi- 
cation of  contagion,  or  by  prohibiting  the  entry  into  the 
ports  of  the  United  States  of  vessels  coming  from  infected 
countries  or  having  contagious  or  infectious  disease  on 
board.  And  in  case  the  President  shall  at  any  time  exer- 
cise the  authority  hereby  conferred  upon  him,  he  shall, 
at  or  before  the  time  of  issuing  such  proclamation  as 
aforesaid,  convene  the  National  Board  of  Health,  to 
meet  at  Washington  in  special  session  within  ten  days 
from  the  date  of  such  notice  of  convention,  and  the  said 
board  shall  thereupon  advise  such  measures  as  it  may 
deem  sufficient  to  meet  the  emergency ;  and  upon  the 
taking  effect  of  such  measures,  with  the  approval  of  the 
President  of  the  United  States  as  herein  provided, 
the  President's  proclamation  aforesaid  shall  cease  to  have 
effect.  It  shall  be  the  duty  of  this  Board  at  all  times  to 
give  prompt  attention  to  any  question  in  sanitary  science 
which  may  be  submitted  to  it  by  the  President. 

Section  7.  It  shall  be  the  duly  of  the  Department  of 
State  to  obtain  from  the  consular  officers  at  foreign  ports 
or  places  all  available  information  in  regard  to  the  sani- 
tary condition  of  such  ports  and  places,  and  to  transmit 
the  same  to  this  board ;  and  it  shall  be  the  duty  of  this 
board  to  obtain  from  the  State  and  municipal  health  au- 
thorities throughout  the  United  States,  and  from  all  other 
available  sources,  weekly  reports  of  the  sanitary  condi- 
tion of  ports  and  places  within  the  United  States,  and 
reports  and  other  matters  relating  to  climatic  and  other 
conditions  affecting  the  public  health,  and  it  shall  pre- 
pare, publish,  and  transmit  to  State  and  other  authorities, 
and  other  proper  persons,  weekly  abstracts  of  such  re- 
ports, consular  reports,  and  other  useful  information  re- 
lating to  the  public  health  ;  and  it  shall  make  to  the 
President,  for  transmission  to  Congress,  an  annual  report 
of  its  transactions,  with  such  recommendations  as  it  may 
deem  important  to  the  public  health  ;  and  the  necessary 
printing  of  the  board  shall  be  done  at  the  Government 
Printing  Office,  upon  the  requisition  of  the  secretary  of 
such  board,  in  the  same  manner  and  subject  to  the  same 
provisions  as  other  public  printing  for  the  several  De- 
partments of  the  Government. 

Section  8.  The  President  of  the  United  States  is  au- 
thorized, when  requested  by  this  board,  and  when  the 
same  can  be  done  without  prejudice  to  the  public  service, 
to  detail  officers  from  the  several  Departments  of  the 
Government,  for  temporary  duty,  to  act  under  the  direc- 
tion of  this  board  in  carrying  out  the  provisions  of  this 
act,  and  such  officers  shall  receive  no  additional  compen- 
sation, except  for  actual  and  necessary  expenses  incurred 
in  the  performance  of  such  duties. 

Section  9.  To  meet  the  expenses  incurred  in  carrying 
out  the  provisions  of  this  act,  the  sum  of  $500,000,  or  so 
much  thereof  as  may  be  necessary,  is  hereby  appropri- 
ated, to  be  disbursed  under  the  direction  of  the  board  ; 
and  the  board  shall  have  authority  to  appoint  such  dis- 
bursing agents  as  it  deems  necessary,  who  shall  give  bond, 
as  in  other  cases,  for  the  faithful  performance  of  their  dnties. 

Secijion  10.  All  acts  and  parts  of  acts  in  conflict  with 
any  of  the  provisions  of  this  act  shall  be  and  are  hereby 
repealed.  

Exonerated. — We  are  pleased  to  state  that  the  phy- 
sicians who  were  censured  by  the  Coroner  in  the  Jaeger 
case  have  been  fully  exonerated.  Thus  ends  what  might 
have  proved  to  have  been  a  professional  scandal . 


690 


THE  MEDICAL  RECORD. 


[December  20,  1884. 


^jexrijemB  un&  ^oticjes. 


The   Principles  and  Practice  of  Gynecology.    By 
Thomas   Addis  Emmet,  M.D.,    LL.D.,  etc.     Third 
edition,  thoroughly  revised.      With  150  illustrations. 
Philadelphia  :  Henry  C.  Lea's  Sons  &  Co,     1884. 
The  originality  and  amplitude  of  resource  which  charac- 
terize the  operative  procedures  of  the  author  are  faith- 
fully mirrored  in  the  goodly  volume  before  us. 

The  first  and  second  editions  of  this  book  are  so  well 
known  to  the  profession  that  it  would  be  an  act  of  super- 
erogation to  enter  into  a  discussion  of  the  merits  of  the 
third  edition,  were  the  latter  merely  a  reprint  of  the 
former.  We  have  essentially  an  almost  new  work  be- 
fore us. 

Honesty  of  purpose,  truthfulness  of  clinical  descrip- 
tion, love  of  his  art,  tempered  by  judicious  fairness — 
these  qualities  speak  in  every  chapter  of  the  book.  It  is 
seldom  that  the  personal  character  of  an  author  is  so 
correctly  reflected  as  we  find  it  in  Dr.  Emmet's  writings. 
To  read  his  description  of  cases  and  commentaries  is 
almost  equivalent  to  seeing,  hearing,  and  knowing  him. 
Those  who  enjoy  the  latter  privilege  are  satisfied  that 
the  teachings  of  our  author  are  based  upon  sincere  con- 
viction,  deduced  from  an  ample  clinical  material.  If 
some  of  these  teachings  are  at  variance  with  the  accept- 
ed views  of  the  majority  of  gynecologists,  it  behooves  the 
latter  to  bear  in  mind  the  character  of  the  author  as  a  man 
and  physician,  and  to  study  with  more  than  usual  care  the 
new  doctrines  and  operative  measures  which  he  pro- 
pounds with  all  the  earnestness  of  his  nature.  Dr.  Em- 
met simplifies  the  treatment  of  diseases  of  women  mate- 
rially in  that  he  not  only  asserts  *^  that  pelvic  cellulitis  is 
by  far  the  most  important  disease  with  which  woman  is 
afflicted,"  but  that  he  refuses  to  recognize  the  distinc- 
tions usually  made  by  authors  between  the  various  in- 
flammatory conditions  in  the  vicinity  of  the  uterus. 
"  The  terms  perimetritis  and  parametritis  are  not  ap- 
plicable, as  they  express  a  theoretical  distinction  only, 
and  the  difference  cannot  be  recognized  clinically." 
These  dicta  mark  a  decided  departure  from  established 
doctrine  and  raise  Dr.  Emmet  to  the  dignity  of  founding 
a  new  school  in  gynecology.  Without  entering  into  the 
argument,  chiefly  clinical,  by  means  of  which  he  seeks  to 
establish  these  radical  views,  it  may  be  granted  that,  if 
the  generalization  of  utero-pelvic  inflammation  does  not 
accrue  to  the  detriment  of  patients  suffering  from  these 
diseases,  we  cannot  demur  with  justice.  A  fine  analyti- 
cal diagnosis  is  "  a  thing  of  beauty,"  but  it  is  not  **  a  joy 
forever  "  if  it  conduce  not  to  the  recovery  of  the  patient. 
In  this  respect  the  aim  of  science  is  fulfilled  by  Dr. 
Emmet's  classification.  The  management  of  these  cases 
is  greatly  simplified,  and  its  success  is  vouched  for  by  the 
logic  of  facts.  The  clinical  history  of  cellulitis,  its  eti- 
ology and  treatment,  are  drawn  with  a  master  pen  ;  but 
nowhere  in  this  volume  does  the  author's  cautious  atten- 
tion to  minute  details,  which  is  the  key  to  his  success, 
appear  more  pronounced  than  in  the  enunciation  of  the 
lines  of  treatment.  Prolonged  hot  water  injections  in 
the  early  stage,  and  less  abundant  injections  continued  in 
the  later  stages,  are  the  chief  reliance. 

The  question  arises  :  Will  Dr.  Emmef  s  radical  views 
on  cellulitis  as  a  fundamental  agency  in  uterine  troubles 
be  accepted  by  the  profession  ?  Our  answer  is,  that 
these  views  have  already  received  practical  indorsement, 
and  are  thus  daily  accepted  by  every  gynecologist,  when 
he  prescribes  hot-water  injections.  That  the  latter  is 
the  most  universal  remedy  in  uterine  disease,  is  a  well- 
recognized  fact.  Its  recommendation  by  Dr.  Emmet 
rapidly  introduced  it ;  its  success,  as  a  chief  or  auxiliary 
measure,  has  maintained  its  position.  It  is  Dr.  Emmet's 
chief  remedy  in  all  shades  of  cellulitis,  and  he  has  thus 
ingeniously,  perhaps  unintentionally,  brought  the  profes- 
sion to  a  recognition  of  the  correctness  of  his  views  in 
the  most  practical  manner.^ 


One  of  the  distinguishing  features  of  the  present  edition 
of  the  work,  is  the  fact  that  several  new  operations  are 
described,  one  of  which,  at  least,  is  destined  to  win  for 
itself  a  lasting  place  among  restorative  procedures  in 
plastic  gynecology.  This  is,  we  believe,  true  of  Dr. 
Emmet's  new  operation  for  restoration  of  the  posterior 
wall  of  the  vagina  in  the  "  so-called  rupture  of  the  peri- 
neum." The  author  claims  that  it  is  "  exceedingly 
doubtful  if  the  perineum  can  be  lacerated  without  the 
tear  extending  through  the  sphincter  ani."  He  recog- 
nizes the  latter  alone  as  a  true  rupture  of  the  perineum, 
for  which  the  well-known  operation,  described  in  former 
editions,  is  still  recommended.  The  larger  number  of 
"  perineal  lacerations,"  however,  are  "  due  to  overstretch- 
ing of  the  pelvic  fascia,  or  to  laceration  at  some  point  of 
fascia  and  muscle."  To  remedy  the  damage  inflicted 
by  this  complication  of  labor,  Dr.  Emmet  gives  the  pro- 
fession a  new  operation  which  appears  to  be  perfect  in 
its  immediate  result,  viz.,  the  restoration  of  the  normal 
configuration  and  dimensions  of  the  vagina.  Upon  this 
point  we  speak  from  actual  'observation.  We  find  the 
new  operation  not  difficult  of  execution,  and  the  claim 
that  it  contributes  to  the  diminution  of  pain  in  the  period 
of  healing,  seems  to  be  substantiated.  It  is  to  be  re- 
gretted, however,  that  it  will  be  difficult  to  comprehend 
the  steps  of  this  operative  procedure  from  the  illustra- 
tions in  the  book.  Two  additional  diagrams,  viz.,  one 
representing  the  process  of  denudation  in  its  prop>er 
line,  and  another  showing  by  dotted  lines  wherein  the 
new  operation  differs  from  and  is  superior  to  the  old 
operation,  would  materially  facilitate  its  comprehension^ 
It  is  to  be  hoped  that  in  the  next  edition,  if  not  in  a 
separate  paper.  Dr.  Emmet  will  favor  the  profession  with 
a  drawing  whic^  will  be  as  superior  to  Fig.  67,  in  the 
delineation  of  the  new  operation  for  restoration  of  the 
posterior  vaginal  wall,  as  is  Fig.  89  of  the  last  edition 
superior  to  Fig.  83  of  the  first,  in  the  illustration  of  the 
operation  for  lacerated  cervix. 

The  new  operation,  when  finished,  leaves  the  vagina 
in  an  almost  virginal  state,  with  the  fourchette  sloping 
inward,  while  the  old  operation  builds  a  dam  in  front  of 
the  vagina,  which  sooner  or  later  yields  in  many  cases. 
If  space  permitted,  we  would  be  glad  to  enter  into  a 
more  detailed  discussion  and  description  of  this  opera- 
tion, as  we  have  seen  it  under  the  hands  of  its  skilful 
designer. 

Another  decided  advance  brought  prominently  for- 
ward in  Dr.  Emmet's  last  edition,  but  foreshadowed  in 
the  second,  is  the  **  button-hole  operation  "  for  the  re- 
lief of  those  distressing  urethral  and  bladder  troubles 
which  are  the  bane  of  many  a  woman's  life,  and  the 
despair  of  many  a  doctor.  The  illustration  of  this  opera- 
tion is  simply  perfect,  as  is  also  the  description  of  the 
steps  of,  and  the  indications  for,  its  performance.  The 
author  claims  more  for  it  than  we  would  at  the  pres- 
ent time  be  willing  to  admit.  But  there  is  no  doubt  that 
the  great  benefits  which  this  ingenious  procedure  opens 
out  in  hitherto  incurable  cases,  will  very  soon  be  appre- 
ciated. The  beautiful  imitation  of  the  ordinary  button- 
hole, which  prevents  irritation  of  the  wound  edges,  to- 
gether with  the  fact  that  incontinence  of  urine  does  not 
result  from  the  mutilation  of  the  urethra,  mark  this  pro- 
cedure as  one  of  the  most  brilliant  achievements  of  surgery. 

The  recognition  of  cellulitis  as  a  dominant  element 
in  gynecic  troubles;  the  introduction  of  hot-water 
douches  for  their  treatment ;  the  operation  for  lacerated 
cervix ;  the  button-hole  operation  in  urethra  and  blad- 
der ;  the  ingenious  and  effective  operation  for  repair  of 
injuries  in  the  posterior  vaginal  wall — these  original  and 
practical  contributions  form  a  pedestal  upon  which  Dr. 
Emmet's  fame  must  securely  rest.  If  his  fertile  brain 
and  skilful  hand  furnish  naught  else  to  the  profession 
but  these,  he  may  be  content  in  the  knowledge  that  he 
has  created  an  era  in  practical  gynecology  to  whose  open- 
ing future  generations  of  physicians  will  ever  turn  with 
reverence  and  gratitude. 


December  20,  1884.] 


THE   MEDICAL  RECORD. 


691 


We  have  dwelt  briefly  upon  the  chief  distinguishing 
characteristics  of  this  third  edition  of  Dn  Emmet's  work, 
and  we  have,  therefore,  been  forced  to  omit  mention  of 
many  valuable  features.  Altogether,  the  work  before  us  is 
an  inexhaustible  fountain  of  clinical  information,  which  no 
practitioner  who  has  the  interest  of  his  clientele  at  heart 
can  afford  to  miss  from  his  library.  Its  practical  teach- 
ings render  it  indispensable  to  the  general  practitioner, 
while  its  novel  views  and  operations  commend  it  to  the 
progressive  gynecologist.  It  is  almost  a  new  book,  for, 
as  the  author  tells  us,  "  The  chapters  on  The  Relation 
of  Education  and  Social  Condition  to  Development; 
those  on  Pelvic  Cellulitis  ;  on  the  Diseases  of  the  Ovary  ; 
on  Ovariotomy,  and  on  Stone  in  the  Bladder,  have  been 
nearly  rewritten.  The  chapters  on  Prolapse  of  the  Va- 
ginal Walls ;  on  Laceration  of  the  Vaginal  Outlet  and 
through  the  Sphincter  and  Perineum ;  on  the  Methods 
of  Partial  and  Complete  Removal  of  the  Uterus  for  Ma- 
lignant Disease  ;  on  the  Surgical  Treatment  of  Fibrous 
Tumors ;  on  Diseases  of  the  Fallopian  Tubes ;  and  on 
Diseases  of  the  Urethra,  are  essentially  new,  containing 
the  views  and  experience  of  the  author  in  a  form  which 
has  not  been  presented  to  the  profession  before.'' 
^^'-  The  type  is  clear,  although  somewhat  condensed  to 
make  room  for  additional  matter ;  the  illustrations  in  the 
main  are  good. 

The  Formation  of  Poisons  by  Micro-organisms. 
By  G.  V.  Black,  M.D.,  D.D.S.  8vo,  pp.  178.  Phila- 
delphia :  P.  Blakiston,  Son  &  Co.  1884. 
The  author  of  this  little  work  possesses  in  an  unusual 
d  *gree  the  faculty  of  seizing  the  main  points  of  an  argu- 
ment and  presenting  them  clearly  and  forcibly.  He  lays 
no  claim  to  origmality  in  his  facts,  and  if  he  has  made 
any  investigations  of  his  own  on  the  subject,  he  does  not 
obtrude  them  in  his  book,  but  gives  the  history  and  pres- 
ent standing  of  the  subject  in  a  concise  and  yet  compre- 
hensive manner,  such  as  no  other  work  with  which  we 
are  acquainted  furnishes.  That  part  of  the  treatise  in 
which  he  endeavors  to  explain  the  modus  operandi  of  the 
bacteria  and  their  congeners  by  the  poisonous  effects  of 
their  waste  products  is  a  truly  delightful  piece  of  logical 
reasoning,  and  will  do  much  to  enable  the  reader  to  ob- 
tain an  understanding  of  the  deadly  work  of  the  micro- 
organisms. The  author  argues  d  priori  by  analogy,  and 
having,  by  a  general  consideration  of  the  laws  of  diges- 
tion and  assimilation,  made  out  a  probability  for  his 
theory,  he  proceeds  to  substantiate  it  by  the  facts  as  far  as 
known.  We  have  no  hesitation  in  pronouncing  it  the 
best  book  for  students,  physicians,  and  scientists,  who 
desire  to  have  in  a  clear  and  condensed  fonn  a  knowl- 
edge and  understanding  of  the  germ  theory  of  disease. 

A  Pharmacopceia  for  the  Treatment  of  Diseases 
OF    THE   Larynx,  Pharynx,  and  Nasal   Passages. 
By  G.  M.  Lefferts,  A.M.,  M.D.     Second  Edition, 
Revised  and  Enlarged.     New  York  and  London :  G. 
P.  Putnam's  Sons.     1884. 
Dr.  Lefferts'  little  volume  forms  a  convenient  collec- 
tion of  the  commoner  formulae  requisite  for  treating  the 
diseases  of  the  upper  air-passages.     It  is  a  work  that  the 
general  practitioner  will  at  times  consult  with  profit  to 
hinnself  and  his  patients. 

The   Kar:  Its  Anatomy,  Physiology,  and  Diseases. 
'  A  Practical  Treatise  for  the  Use  of  Medical  Students 

and   Practitioners.     By  Charles  H.  Burnett,  A.M., 

M.D.     With  One  Hundred  and  Seven  Illustrations. 

Second  Edition,   Revised   and  Rewritten.     Pp.  585. 

Philadelphia :  Henry  C.  Lea's  Son  &  Co.  1884. 
Sbvkn  years  have  elapsed  since  the  publication  of  the 
first  edition  of  this  work ;  in  this  time  the  advances  in  the 
science  of  otology  have  been  rapid  and  of  an  eminently 
practical  character,  so  that  in  the  work  of  revision  for 
this  second  edition  csf  the  treatise  the  author  found  many 
alterations  necessary;   portions  of  the  book  had  to  be 


entirely  rewritten,  whilst  much  material  found  to  be  ob- 
solete was  omitted. 

Dr.  Burnett  seems  to  have  entered  on  the  laborious 
task  of  giving  the  profession  a  complete  treatise  on  the 
ear  at  a  most  auspicious  moment,  since  he  brings  to  the 
work  a  ripe  experience  both  as  practitioner  and  writer ; 
and  by  acknowledging  his  indebtedness  to  both  the  valu- 
able contributions  of  his  American  confrlresy  and  of  the 
accumulated  knowledge  of  German,  English,  French,  and 
other  laborers  in  the  field  of  otology  the  conceit  of  writ- 
ing-a  book  merely/rom  the  narrow  standpoint  of  individ- 
ual experience  is  notably  absent. 

The  author  informs  us  in  the  preface  that  special  atten- 
tion has  been  given  in  the  present  edition  to  the  follow- 
ing subjects,  namely:  the  abnormalities  of  the  auricle, 
otomycosis,  the  treatment  of  aural  polypi,  and  the  diag- 
nosis, etiology,  and  treatment  of  aural  vertigo.  The  work 
is  divided  into  sections  as  follows : 

Part  I. — Anatomy  and  physiology  of  the  external  ear, 
comprising  the  auricle,  the  external  auditory  canal,  and 
the  membrana  tympani.  The  middle  ear :  The  tympanic 
cavity,  the  Eustachian  tube,  and  mastoid  portion.  The 
internal  ear:  The  labyrinth  and  auditory  nerve,  and 
scheme  of  relationship  between  the  middle  and  inter- 
nal ear. 

Part  II. — The  examination  of  patients,  the  necessary 
instruments  and  their  employment,  the  consideration  of 
sound,  hearing,  and  tests  of  the  latter,  organic  defects  of 
the  auricle,  and  its  cutaneous  affections,  including  mor- 
bid growths  and  injuries,  diseases  of  the  external  auditory 
canal,  foreign  bodies  in  the  external  ear,  and  the  results 
of  inflammation  and  injury,  afifections  of  the  membrana 
tympani,  including  acute  and  chronic  inflammation,  in- 
juries and  morbid  growths. 

Under  the  section  devoted  to  the  middle  ear  are  con- 
sidered acute  and  chronic  catarrhal  inflammation  of  the 
middle  ear  and  their  treatment,  functional  disturbances, 
noises  in  the  head,  etc.,  and  organic  disturbances.  Chap- 
ters are  assigned  to  acute  and  purulent  inflammation  of 
the  middle  ear,  their  course  and  consequences. 

Section  VI.  is  devoted  to  diseases  of  the  internal  ear, 
and  Section  VII.  to  deaf-mutes,  and  partially  deaf  chil- 
dren, the  methods  of  their  relief  and  education. 

While  the  otologist  might  differ  from  the  author  in 
many  minor  points  of  theory  and  practice,  the  student 
and  practitioner  will  find  this  work  fully  up  to  the  pres- 
ent time  in  all  of  the  subjects  of  which  it  treats,  and  a 
safe  guide  to  follow  in  practice.  The  various  topics  per- 
taining to  otology  have  been  handled  with  unwearied 
zeal  and  patience;  indeed  the  literature  of  the  subject 
has  been  so  exhaustively  brought  forth  that  the  reviewer 
is  at  a  loss  to  know  just  where  to  take  up  the  thread  of 
the  text  for  practical  criticism.  Perhaps  it  might  be  said 
the  author  has  introduced  some  instruments  for  the  ex- 
amination of  the  ear  which  cannot  be  practically  adopted 
by  the  specialist  even ;  but,  after  all,  this  has  a  certain  in- 
terest as  showing  what  efforts  have  been  made  to  increase 
our  means  of  finding  out  more  about  the  diseases  of  the 
ear.  The  author  adheres  to  the  employment  of  the  hard- 
rubber  nose-piece  in  inflation  of  the  tympanum  by  means 
of  the  air-bag ;  this  appliance  has  long  fallen  into  disuse 
in  New  York,  whfere  a  glass  bulb  is  used  to  close  up  the 
meatus  of  one  nostril,  a  method  less  disagreeable  to  the 
patient  and  more  cleanly  than  the  insertion  of  a  long 
slender  tube  into  the  nose.  The  above  are  trivial  matters, 
after  all,  and  one  would  scarcely  be  warranted  in  taking 
up  further  space  in  an  analytical  examination  of  all  the 
points  of  interest,  since  the  work  is  likely  soon  to  be  in 
the  hands  of  every  one  interested  in  the  subject. 

Otologists  must  thank  Dr.  Burnett  for  taking  a  step  in 
advance  in  the  matter  of  aural  nomenclature,  and,  al- 
though there  is  yet  some  room  left  for  improvement  in 
this  respect,  he  has  left  a  better  state  of  things  than  pre- 
viously existed.  The  book  is  well  made  up,  and  the 
illustrations  are  good  in  the  main  ;  the  economy  of  the 
publishers,  however,  in   producing   inferior   pictures  o^ 


692 


THE   MEDICAL  RECQRD. 


[December  20,  1884. 


the  human  face,  as  shown  in  the  explanatory  cuts,  can- 
not be  commended. 

On  the  whole  this  treatise  will  be  an  invaluable  acqui- 
sition to  the  library  of  the  American  practitioner ;  the 
subjects  are  conveniently  arranged  for  reference,  and  the 
index  will  be  found  unusually  complete. 

The    Physician's    Visiting    List    for    1885.      Phila- 
delphia :  P.  Blakiston,  Son  &  Co. 
This   i  opular   visiting  list   appears  in   its   thirty-fourth 
year.     There  are  no  changes  in  the  plan  of  its  arrange- 
ment. 
Micro-organisms  and  Disease.     By  E.  Klein,  M.D., 

F.R.S.  London  :  Macraillan  &  Co.  1884. 
This  little  volume  is  a  reprint  of  a  -  ei  ies  of  articles  that 
were  published  in  the  London  Practitioner,  It  is  by  no 
means  a  complete  treatise,  but  may  serve  as  a  conveni- 
ent introduction  to  the  study  of  microbes  in  their  relation 
to  disease. 

A  Text-book  of  Pathological  Anatomy  and  Patho- 
^  genesis.  By  Ernest  Ziegler.  Translated  and  Edited 
"for  English  Students  by  Donald  MacAlister,  M.A., 
M.B.  Part  IL  Special  Pathological  Anatomy,  Sec- 
tions 1-8.  Pp.  365.  New  York  :  William  Wood  &  Co. 
1884.  Wood's  Library  of  Standard  Medical  Authors. 
The  editor  and  translator  of  this  work,  Dr.  MacAlister, 
states  that  he  had  expected  to  make  the  present  volume 
the  concluding  one.  Owing  to  the  great  demand  for  the 
first  sections,  however.  Professor  Ziegler  was  unable  to 
complete  his  work  as  early  as  expected.  The  present 
volume  does  not,  therefore,  finish  the  work.  It  takes  up 
the  various  branches  of  special  pathology,  beginning 
with  blood  and  lymph  and  ending  with  the  alimentary 
tract  and  the  liver  and  pancreas.  The  kidneys,  lungs, 
and  nervous  system  remain  yet  to  be  treated  of. 

We  can  hardly  praise  too  highly  this  volume.  It  treats 
every  branch  of  the  subject  with  a  most  satisfactory  com- 
pleteness, yet  it  is  not  prolix,  nor  does  it  deal  in  hy- 
potheses or  superfluous  discussion.  Numerous  biblio- 
graphical references  are  given.  The  illustrations  are 
excellent  and  vastly  superior  to  what  we  are  accustomed 
to  find  in  this  series.  The  work  when  completed  will 
take  its  place  as  the  best  pathological  text-book  in  the 
English  language. 

The  Elements  of  Physiological  and  Pathological 
Chemistry:  A  Handbook  for  Medical  Students  and 
Practitioners,  containing  a  general  account  of  Nutri- 
tion, Foods,  and  Digestion,  and  the  Chemistry  of  the 
Tissues,   Organs,  Secretions,   and  Excretions  of  the 
Body  in  Health  and  Disease,  together  with  Methods 
of  Preparing  or  Separating  their  Chief  Constituents, 
as  also  for  their  Examination  in  Detail,  and  an  Outline 
Syllabus  of  a  Practical  Course  of  Instruction  for  Stu- 
dents.  By  T.  Cranstoun  Charles,  M.D.    Illustrated 
with  38  engravings  on  wood  and  a  chromo-lithograph. 
8vo,  pp.  463.     Philadelphia  :  Henry  C.  Lea's  Son  & 
Co.     1884. 
The  very  ample  title-page  which  is  given  above  gives  so 
full  an  idea  of  the  scope  of  the  author's  work  that  an 
analytical  review  is  hardly  necessary.     Dr.  Charles,  as 
his  title-page  would  almost  indicate,  is  fully  impressed 
with  the  importance  and  practical  reach  of  his  book.     A 
perusal   of  its  contents,  or  rather  of  selected  portions 
thereof,  shows  that  the  author's  confidence  in  himself  is 
not  misplaced,  and  that  he  has  not  only  got  hold  of  an 
important  branch  of  medical  science,  but  has  treated  it 
in  a  competent  and  instructive  manner.     The  physician, 
however,  must  be  impressed,  in  reading  this  as  well  as 
many  other  of  the  works  that  are  pouring  so  rapidly  from 
the  medical  press,  that  his  work  of  acquiring  knowledge 
is  never  done,  and  that  the  fields  in  which  he  can  and 
perhaps  ought  to  acquire  technical  skill  are  rapidly  multi- 
plying.    If  he   chooses   to   take   up  physiological  and 
pathological  chemistry  we  cannot  recommend  a  better 
work  than  the  present.     In  fact  it  fills  a  gap  in  medical 


text-books,  and  that  is  a  thing  which  can  be  rarely  said 
nowadays. 

Physiological  chemistry  generally  means  in  practice 
urinary  analysis.  In  accordance  with  this  fact.  Dr. 
Charles  has  devoted  much  space  to  the  elucidation  of 
urinary  mysteries.  He  does  this  with  much  detail,  and 
yet  in  a  practical  and  intelligible  manner.  In  fact,  the 
author  has  filled  his  book  with  many  practical  hmts,  as 
well  as  with  recondite  formulae  and  complicated  reactions. 
It  is  needless  to  say  that  the  volume  is  published  in  the 
best  style. 

On  Sclerosis  of  the  Spinal  Cord  :  Including  Loco- 
motor Ataxia,  Spastic  Spinal  Paralysis,  and  other  Sys- 
tem Diseases  of  the  Spinal  Cord,  their  Pathology, 
Symptoms,  Diagnosis,  and  Treatment.  By  Julius 
Althaus,  M.D.,  M.R.C.P.  With  nine  engravings, 
pp.  394.     New  York:  G.  P.  Putnam's  Sons.     1885. 

The  physician  in  general  practice  is  doubtless  some- 
times a  little  puzzled  at  the  extradorinary  amount  of  at- 
tention bestowed  upon  locomotor  ataxia  by  neurologists. 
It  is  a  rare  disease.  Among  a  million  of  people  only 
two  or  three  die  from  it  annually,  and  the  country  prac- 
titioner sees  only  two  or  three  cases  in  as  many  decades. 
But  tabes  dorsalis  is,  scientifically,  a  most  interesting  af- 
fair, and,  practically,  when  it  does  occur  it  means  years 
of  distress  and  agony  to  the  patient  No  one  will  find 
fault,  therefore,  at  the  attempts  to  secure  more  knowl- 
edge  of  its  nature  and  more  skill  in  its  treatment.  Dr. 
Althaiis'  book  is  really  a  treatise  on  locomotor  ataxia, 
with  a  few  chapters  on  the  other  scleroses  added  for 
completeness.  It  embodies  some  of  the  articles  that 
have  already  appeared  in  English  medical  journals. 
Taken  altogether,  it  is  a  most  interesting  and  practical 
contribution  to  the  subject.  The  author  is  of  the  opin- 
ion that  a  great  deal  can  be  done  for  tabes  if  taken  early, 
and  he  is  especially  earnest  in  urging  that  the  general 
practitioner  be  made  familiar  with  the  premonitory  symp- 
toms of  the  disease. 

Dr.  Althaus  believes  thoroughly  in  the  great  impor- 
tance  which  syphilis  plays  in  the  etiology  of  the  disease. 
For  this  reason  he  makes  iodide  of  potassium  a  promi- 
nent drug  in  his  armamentarium.  He  commends  ergot 
and  electricity  highly.  Nitrate  of  silver  is  spoken  of 
with  more  caution. 

The  book  is  written  in  a  plain  and  non-technical  style, 
and  will  be  found  attractive  and  instructive  by  all  classes 
of  medical  men. . 

Henke's   Atlas  of   Surgical  Anatomy.     Translated 
and  Edited  by  W.  A.  Rothacker,  M.D.,  Pathologist 
to  the  Cincinnati  Hospital  and  Lecturer  on  Pathologi- 
cal Anatomy  in   Miami  Medical  College.      4to,  with 
81  plates  and  123  figures.     Cincinnati :  A.  £.  WLlde& 
Co.     1884. 
The  well-known  German  Atlas  of  Henke,  on  regional 
and  surgical  anatomy,  has  now  for  the  first  time  been 
reproduced  in  this  country.     It  comes  to  us  in  a  form 
worthy  of  the  original,  the  acknowledged  excellence  of 
which  has  rendered  changes  and  additions  unnecessary. 
As  the  American    editor  implies  in   his   preface,  it  is 
essentially  a  working  Atlas,  and  will  be  found  valuable  by 
the  busy  practitioner,  as  a  convenient  book  of  anatomi- 
cal and  surgical  reference. 

Treatment  of  Diseases  of  Women,  Puerperal  and 
Non-Puerperal.  By  Charles  H.  Goodwin,  M.D. 
Second  Edition.  New  York  :  C.  H.  Goodwin.  1884. 
A  SECOND  edition  of  Dr.  Goodwin's  Treatment  of  Dis- 
eases of  Women  has  just  appeared.  The  work,  it  is 
stated,  has  been  revised,  but  differs  in  no  material  respect 
from  its  first  issue.  It  is  a  compilation  of  the  late  views  of 
many  of  New  York's  most  eminent  obstetricians  and  g3aie- 
cologists,  and  as  such  commends  itself  to  those  who  have 
either  not  the  time  to  read  these  various  writers  in  ex* 
tenso  or  to  whom  their  original  contributions  are  inacces- 
sible.    We  cannot  commend  it  too  highly. 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


693 


Reports  at  ^ocUtus. 


NEW  YORK  ACADEMY  OF  MEDICINE. 

SECTION  IN  OBSTETRICS. 

S^afeti  Meeting,  November  28M,  1884. 

Alexander  S.  Hunter,  M.D.,  Chairman. 

ANTEFLEXION  OF  THE  UTERUS  AND  ITS  ASSOCIATED 
PATHOLOGICAL  CONDITIONS — THEIR  PREVENTION  AND 
TREATMENT. 

Dr.  W.  Gill  Wylie  read  a  paper  on  the  above  sub- 
ject, which  was  the  coDtinuation  of  a  paper  previously 
published  in  Xh^  American  Journal  of  Obstetrics.  The 
present  paper  referred  especially  to  the  prevention  and 
treatment  of  anteflexion. 

Prevention, — The  true  etiology  of  the  disease  indicates 
the  steps  to  be  taken  to  prevent  it.  As  long  as  delicate 
children  are  born  and  are  able  to  reach  maturity,  women 
will  suffer  with  small,  imperfectly  formed  and/legenerafed 
genital  organs.  We  might  expect  to  find  anteflexed  uteri 
among  these  children,  although  born  of  healthy  parents. 
To  prevent  anteflexion  or  imperfect  development  and 
degeneration  of  the  generative  organs  children  with  good 
constitutions  should  be  kept  in  good  health  until  fully 
matured,  and  delicate  and  stunted  children  should  be  so 
treated  as  to  increase  their  physical  strength  and  have 
a  surplus  force  for  the  development  of  the  organs  of 
generation.  • 

Local  treatment,  if  given  at  all,  should  aim  "at  stimu- 
lating healthy  development. 

Treatment. — These  cases  usually  seek  medical  advice 
on  account  of  dysmenorrhoea  or  irregular  menstruation. 
Yet  not  unfrequently  a  woman  will  bear  with  the  pain  for 
years,  and  finally  consult  a  physician  for  sterility. 

Dr.  Wylie  rarely  makes  a  local  examination  in  unmar- 
ried women  for   either  dysmenorrhoea  or  amenorrhoea 
without   first  trying  the  eff"ect  of  general  treatment.     By 
far  the  most  common  type  among  the  well- to-do  classes 
is  that  where  imperfect  development  is  plainly  indicated. 
In  Sims'  position,  with  his  speculum  in  place,  a  properly 
curved  sound  can  be  readily  passed  to  the  os  internum ; 
at  this  point  tliere  may  be  some  resistance,  and  as  the  in- 
strument passes  the  patient  usually  complains  of  sharp 
pain.     The  fundus  may  be  found  sensitive  to  the  touch 
of  the  sound,  and  not  unfrequently  its  withdrawal  is  fol- 
lowed by  blood,  although  it  may  have  been  passed  with 
the  greatest  care.    He  usually  begins  the  local  treatment 
of  such  a  case  by  inserting  a  small  piece  of  borated  cot- 
ton, saturated  with  pure  glycerine,  against  the  anterior 
lip  of  the  cervix,  crowding  it  somewhat  back  into  the 
vagina.      The  cotton  rolls  into  a  ball  which  tends  to  dis- 
place the  cervix  backward  and  lift  the  fundus.     A  string 
is  attached  to  the  cotton,  by  means  of  which  the  patient 
can  remove  it,  which  she  is  instructed  to  do  in  twenty- 
four  hours.     The  pledgets  are  put  in  two  or  three  times 
a  week  until  the  patient  bears  the  vaginal  examination 
without  pain.     The  patient  is  also  instructed  to  use  hot- 
water- vaginal  douches  during  the  intervening  days.     If 
the   case   is  complicated  by  peri-uterine  congestion  or 
subacute  inflammation,  the  simple  glycerine  pledgets  are 
replaced   b^  similar  pledgets  saturated  with  a  mixture  of 
alum,  one  part  to  pure  glycerine  fifteen  parts,  and  suffi- 
cient  carbolic  acid  to  act  as  a  disinfectant,  usually  one 
drachm  to  the  pint.     The  size  of  the  pledgets  is  grad- 
ually increased.     As  a  rule  an  ordinary  case  will  change 
much    in    two  or  three  weeks  by  this  preparatory  treat- 
ment.    Occasionally  six  or  eight  weeks  of  such  treatment 
will  be  required  before  the  next  step  can  be  safely  under- 
aken. 

£>ilatation. — The  patient  being  in  Sims'  position,  the 
vagina  is  sponged  out  with  a  solution  of  i  to  3,000 
of  bichloride,  or  i  to  2c  of  carbolic  acid.  All  in- 
struments   are  kept   in    a    solution    of   carbolic  acid. 


Then  the   Sims*    uterine  dilator  is  inserted    into  the 
uterine  canal.     The  dilator  when  properly  curved  can 
be  passed  almost  as  easily  as  the  sound.     The  blades 
should  be  forced  apart  about  two  lines.     The  amount 
of  force  required  for  this  amount  of  dilatation  will  vary 
very  greatly,  but  usually  in  old  cases  it  is  considerable, 
especially  those  of  an  imperfectly  developed  type.     This 
procedure  causes  more  or  less,  and  in  some  cases,  in- 
tense pain.    The  dilator  is  withdrawn  and  the  cervical 
director  introduced  to  the  os  internum.     The  applicator, 
previously  wrapped  with  cotton,  is  dipped  into  pure  car- 
bolic acid,  the  free  acid  having  been  rubbed  off",  and  is 
passed  through  the  tube  of  the  director  directly  to  the  os 
internum,  and  thoroughly  applied  by  turning  it  about  and 
slightly  withdrawing  the  tube  and  applicator.      About 
twenty  grains  of  iodoform  are  blown  against  the  cervix  as 
the  speculum  is  withdrawn.     In  some  cases  the  pain  is 
immediately  relieved.     Rarely,  the  patient  complains  of 
pain  for  several  hours.     When  properly  performed,  as 
directed  above,  and  if  antiseptic  precautions  were  used, 
he  had  never  seen  any  harm  from  this  treatment.     The 
first  dilatation  can  be  made  at  the  patient's  home,  and 
she  is  kept  in  bed  for  the  rest  of  the  day,  or  until  all'dis- 
turbance  hasTceased.     As  a  rule,  it  is  best  to  allow  at 
least  a  week  to  pass  before  the  dilatation  is  repeated. 
The  glycerine  pledgets  can  be  inserted  as  usual  in  the 
meantime.      Sometimes  he  repeats  the  dilatation  three 
times  between  the  menses,  but  usually  twice  is  sufficient, 
and  if  the  dilatation  can  be  carried  to  a  point  where  the 
blades  are  four  lines  apart  at  the  os  externum,  the  dys- 
menorrhoea is  relieved  in  the  majority  of  cases  where 
there  is  no  active  endocarditis,  or  endo-cervicitis,  and  in 
the  majority  of  cases  it  is  the  beginning  of  a  permanent 
cure. 

In  married  women,  if  nothing  is  done  to  prevent  im- 
pregnation, sterility  will  often  be  cured  by  this  simple 
treatment,  but  in  certain  cases  the  method  causes  only 
temporary  relief,  and  it  becomes  necessary  to  resort  to 
Sims'  operation,  which  is  division  or  divulsion  and  in- 
cision, with  the  use  of  a  glass-plug  or  some  pessary,  or, 
what  he  liked  better,  a  hard  rubber  drainage-tube  con- 
taining deep  grooves. 

Dr.  Wylie  performs  Sims'  operation  with  some  modi- 
fication. He  divides  the  posterior  wall  of  the  cervix 
in  the  median  line  for  half  an  inch  or  more,  according  to 
the  length  of  the  infra-vaginal  part.  The  lining  mem- 
brane is  divided  the  full  length  of  the  cervix,  and  the 
muscular  walls  are  also  divided  for  some  distance  under 
the  external  mucous  membrane  covering  the  infra-vaginal 
cervix.  He  regarded  it  as  a  mistake  to  divide  all  the 
muscles,  and  especially  the  vaginal  mucous  membrane  of 
the  cervix  as  far  as  to  the  vaginal  junction.  After  this 
incision  the  dilator  is  introduced  and  the  os  internum 
freely  divulsed.  Dr.  Sims  always  divided  the  anterior 
wall  at  the  os  internum, .  but  Dr.  Wylie  had  lately 
trusted  to  the  dilators  to  overcome  all  of  the  constriction 
at  this  point,  for  he  had  never  seen  a  full-sized  plug  in- 
troduced after  incision  as  far  as  the  os  internum  without 
the  free  use  of  the  dilator.  The  dilatation  should  be  done 
slowly  so  as  to  give  time  for  the  tissues  to  stretch  and 
not  to  tear. 

Dr.  WyUe  had  never  believed  in  the  necessity  of  the 
bilateral  operation.  In  those  cases  where  Dr.  Sims  re- 
commended it  he  would  dilate  or  divulse  and  keep  open 
with  a  drainage-tube.  If  the  dilatation  is  imperfectly 
done  the  relief  is  only  temporary,  but  when  thoroughly 
done  and  repeated,  say  twice  in  two  or  three  months,  it 
will  often  effect  a  permanent  cure  in  cases  of  even  ten 
years'  standing.  Child-bearing  is  the  best  means  of 
complete  development  and  making  a  permanent  cure  in 
such  cases. 

Sponge-tents, — For  .more  than  ten  years  he  had  not 
used  tents  in  these  cases. 

Dilatation  by  sound, — The  uterus  is  too  movable  and 
elastic  to  permit  of  the  use  of  sounds  to  the  best  advan- 
tage, and  many  cases  have  been  sounded  up  to  the  os  in- 


694 


THE  MEDICAL  RECORD. 


[December  20,  1884. 


ternum  and  not  beyond.  Still  he  had  to  confess  that 
we  could  more  easily  dispense  with  the  uterotome  than 
with  uterine  dilators,  but  dilators  could  do  serious  harm 
when  dilatation  was  carried  too  far,  and  if  one  use  a 
screw  to  force  open  the  dilators  the  risk  was  greater  than 
when  he  used  his  hand  or  hands  to  regulate  the  amount 
of  dilatation. 

If  the  use  of  pessaries  in  anteflexion  had  never  been 
taught,  much  harm  would  have  been  averted,  and  more 
progress  made  in  the  right  direction.  As  to  the  use  of 
stem-pessaries  for  straightening  the  canal  they  may  do 
good  by  stimulating  development,  but  many  of  them  are 
dangerous  instruments.  In  some  cases  he  used  a  drain- 
age-tube of  hard  rubber  with  one  or  more  deep  grooves 
in  it,  the  object  being  to  keep  up  perfect  drainage,  but 
not  with  the  idea  of  using  a  splint  on  the  fractured  or 
bent  uterus. 

Dr.  Wylie  then  spoke  of  the  complications,  and  gave 
the  following  conclusions  to  which  he  had  arrived  : 

First — There  is  undoubtedly  a  certain  number  of 
cases  in  which  a  marked  degree  of  anterior  curvature 
gives  no  painful  symptoms. 

Second. — Anterior  displacements  are  the  result  rather 
than  the  cause  of  pathological  changes  in  the  uterus. 
They  may  add  to,  and  sometimes  intensify,  disease,  but 
are  rarely,  if  ever,  the  primary  cause. 

Third, — Dysmenorrhoea  with  anteflexion  is  rarely,  if 
ever,  chiefly  and  directly  due  to  the  flexion,  but  the  latter 
in  some  cases  may  aggravate  the  pathological  conditions 
which  are  the  real  cause  of  the  pain. 

Fourth, — The  attempt  to  correct  anterior  displacements 
by  the  use  of  pessaries  is  rarely,  if  ever,  sufficient  to  ef- 
fect a  cure  unless  the  cervix  is  dilated  at  the  same  time, 
or  other  pathological  conditions  are  treated.  The  use  of 
mechanical  supports  may  give  some  relief,  but  they  are 
often  merely  palliative,  and,  as  used  by  many,  they  fre- 
quently do  harm. 

Fifth, — The  true  morbid  condition  of  the  uterus  in  most 
cases  of  anteflexion  is  one  of  imperfect  development, 
while  the  uterine  canal  is  more  or  less  stenosed  by  the 
degeneration  and  contraction  of  the  uterine  tissues,  and 
the  mucous  lining  is  degenerated  and  atrophied,  often 
hyperaesthetic,  especially  in  that  part  of  the  organ  where 
the  circular  fibres  are  most  powerful  and  contracted, 
namely,  at  the  os  internum. 

Sixth. — If  the  above  is  true,  the  treatment  obviously 
would  be  to  stimulate  development  by  improving  the 
general  health  and  by  the  local  use  of  electricity,  to  re- 
lieve the  stenosis  by  dilatation,  or  division  and  divulsion, 
to  effect  drainage,  and  to  bring  about  a  healthy  condition 
of  the  mucous  lining. 

Dr.  H.  T.  Hanks  said  he  was  certainly  very  thankful 
to  T>r.  Wylie  for  his  excellent  paper  upon  this  subject, 
especially  because  it  was  a  subject  worthy  ol  considera- 
tion by  gynecologists.  He  had  been  very  much  inter- 
ested  in  the  statement  made  by  Professor  Thomas  in  his 
address  before  the  New  York  State  Medical  Association, 
namely,  that  there  was  such  a  thing  as  curing  anteflexion 
and  dysmenorrhoea  by  rapid  and  forcible  divulsion,  and 
he  thought  many  of  us  had  yet  to  learn  that  this  procedure 
could  be  resorted  to  with  almost  uniform  benefit.  Dr. 
Hanks  believed  that  four-fifths  of  all  cases  of  anteflexion 
which  needed  treatment  could  be  cured  by  rapid  and  for- 
cible dilatation.  The  results  of  treatment  in  his  cases 
had  been  the  same  as  Dr.  Wylie  had  reported ;  that  is,  he 
had  effected  cure  in  thirty-three  or  four  out  of  thirty-five 
cases.  He  had  found  the  hard-rubber  dilators  to  which 
his  name  had  been  attached  as  serviceable,  in  the  majority 
of  cases,  as  any  instrument  which  could  be  employed. 
He  had  used  the  instruments  recommended  by  Dr.  Ball, 
Dr.  Sims,  Dr.  Goodell,  Dr.  EUinger,  and  others,  and  they 
were  excellent  instruments. 

One  reason  for  resorting  to  this  method  of  treatment 
was  the  fact  that  there  was  no  deformity  after  rapid  and 
forcible  divulsion,  and  there  was  no  doubt  that  a  new 
condition  of  the  tissues  was  established  as  a  result  of  the 


thickening  which  took  place  after  the  operation,  and  which 
in  some  cases  requires  some  little  ame  to  remove.  If  the 
canal  is  dilated  to  fifteen  or  eighteen,  American,  scale,  it 
will  not  contract,  as  some  had  supposed. 

With  reference  to  after-treatment,  he  always  kept  his 
patients  in  bed  for  six  or  eight  days,  and  more  or  less 
under  the  influence  of  opium.  It  might  not  be  necessary 
but  he  had  always  done  it,  and  had  not  had  pelvic  peri- 
tonitis develop  until  his  patients  had  gotten  up  and  been 
about  the  house,  and  it  was  evident  that  the  pelvic  in- 
flammation was  due  to  some  indiscretion. 

With  reference  to  instruments  he  thought  that  Dr. 
Ball's,  if  it  could  be  bent,  would  be  betterthan  any  which 
had  been  devised. 

There  was  one  peculiarity  which  he  wished  to  naen- 
tion,  and  it  was  that  dilatation  was  apparently  done  by 
pressing  the  hands  together,  but  it  would  be  noticed  that 
the  points  of  the  instrument  within  the  internal  os  did 
not  always  dilate  so  much  as  was  supposed. 

He  did  not  claim  so  much  for  the  hard-rubber  dilators 
as  formerly,  but  he  always  knew  when  one  passed  through 
tha  internal  os,  and  the  operator  always  knew  just  how 
much  the  internal  os  was  dilated.  He  thought  that  this 
was  one  of  the  advantages  which  the  hard-rubber  dilator 
had  over  the  Sims  or  the  Peaslee  sound. 

Another  advantage  which  the  hard-rubber  instrunaent 
gave  was  that  it  could  be  turned  over  and  retroflexion  of 
the  uterus  produced.  In  this  manner  the  anterior  wall 
of  the  cervix  was  stretched  somewhat,  which  he  had 
thought  was  of  some  advantage.  However,  either  in- 
strument could  do  the  work  well  in  the  hands  of  skilled 
operators. 

The  Chairman  had  been  especially  pleased  to  hear 
Dr.  W^lie  direct  attention  in  his  paper  to  the  necessity 
of  havmg  the  patient  in  a  good  general  condition  before 
resorting  to  any  operation.  Some  years  ago  he  per- 
formed rapid  dilatation  in  many  cases,  and  produced 
pelvic  cellulitis  in  many  instances,  and  in  some  pelvic 
peritonitis,  and  while  Dr.  Hanks  had  expressed  the  ur- 
gent desire  that  the  teaching  of  the  treatment  by  rapid 
dilatation  should  be  repeated  frequently,  the  Chairman 
hoped  that  with  each  instruction  there  would  be  given 
the  caution  that  the  pelvic  organs  should  be  in  as  healthy 
a  condition  as  possible  under  the  circumstances,  before 
resorting  to  any  operative  procedure,  as  he  had  become 
abundantly  satisfied  that  the  ill  results  which  followed  in 
his  cases  were  due  to  the  lack  of  this  preparatory  treat- 
ment. 

With  reference  to  instruments,  he  thought  a  good  deal 
depended  upon  the  dexterity  of  the  operator.  A  man 
was  very  poorly  qualified  to  dilate  the  cervix  if  he  was 
unable  to  say  whether  or  not  the  instrument  had  entered 
the  OS  internum. 

Some  years  ago  he  devised  an  instrument  for  dilating 
the  OS  internum,  and  thought  that  it,  more  than  any  other 
instrument,  was  capable  of  entering  that  portion  of  the 
canal  with  the  greatest  ease,  and  it  had  the  capacity  of 
dilating  the  interhal  os  to  any  extent  desired. 

Notwithstanding,  he  thought  he  had  gained  a  great 
deal  in  the  way  of  the  dilator,  it  seemed  to  him  that  the 
best  dilator  was  the  circular  wedge,  especially  for  the 
uterine  canal. 

With  reference  to  the  point  made  by  Dr.  Hanks  con- 
cerning the  capacity  of  the  instrument  to  r^troflex  the 
uterus,  it  was  a  question  whether  that  manipulation 
would  be  allowable  in  very  many  cases,  because  the  vio- 
lence don^  in  the  dilatation  of  the  os  internum  was  about 
as  much  as  could  safely  be  endured  at  one  sitting,  par- 
ticularly if  the  patient  was  not  under  an  anaesthetic. 

Dr.  Hanks  thought  no  judicious  surgeon  would  at- 
tempt to  dilate  the  uterine  canal  without  thoroughly 
anaesthetizing  his  patient.  With  regard  to  sounds,  no 
one  should  attempt  to  use  an  instrument  larger  than  a 
small  Simpson  sound,  if  he  wished  to  dilate  without  an 
anaesthetic. 

The  Chairman  directed  attention  to  two  other  points 


December  20,  1884.] 


THE  MEDICAL  RECORD. 


^95 


which  Dr.  Wylie  had  mentioned.  First,  Dr.  Wylie  sel- 
dom makes  an  incision  in  the  anterior  wall  of  the  cervix, 
and  in  that  he  departs  from  the  method  employed  by  Dr. 
Sims  and  does  so  without  giving  his  reasons.  It  would 
seem  that  if  the  incision  was  necessary  at  all  it  would 
be  necessary  at  that  point. 

The  Chairman  also  suggested  whether  it  would  not  be 
well  to  introduce  a  smaller  pessary  with  an  olive  bulb  to 
prevent  union  after  the  incision  had  been  made. 

The  author  of  the  paper  also  made  reference  to  the 
rubber  stem  pessary  with  a  groove  in  its  side.  The  chair- 
man supposed  the  preference  for  the  hard  rubber  was  the 
fact  that  the  groove  could  not  be  made  in  glass.  Other 
things  bein§  equal,  he  should  prefer  glass.  The  chairman 
then  exhibited  several  glass  lubes  which  he  had  used, 
having  a  hole  through  the  centre,  and  they  had  been 
made  so  strong  that  it  was  impossible  to  break  them  with 
the  fingers. 

Dr.  Sell  said  that  if  there  was  any  comparison  to  be 
made  between  divulsion  in  the  cervix  uteri  and  the  same 
procedure  in  the  urethra  of  the  male,  he  would  say  that 
the  plan  advocated  by  Dr.  Wylie  was  very  much  the 
best. 

He  could  not  exactly  say  that  we  had  reached  the  time 
when  dilators,  such  as  Peaslee's,  should  be  altogether 
thrown  aside.  He  had  used  them  when  divulsion  was 
not  in  vogue,  and  had .  succeeded  in  curing  his  patients. 

He  had  been  pleased  to  hear  that  the  best  method  of 
treatment  was  pregnancy,  and  he  had  succeeded  in  many 
cases  with  the  introduction  of  Peaslee's  sound  ;  sometimes 
he  used  a  tent,  occasionally  slightly  nicking  the  cervix 
just  sufficiently  to  admit  the  probe,  in  establishing  a  con- 
dition which  permitted  pregnancy  and  cure  of  the  patient. 
He  was  especially  pleased  with  the  remarks  made  by  Dr. 
Wylie  concerning  the  preparatory  treatment,  but  did  not 
hear  anything  especial  with  reference  to  medical  treat- 
ment, as  such,  in  these  cases.  Dr.  Sell  then  spoke  of 
the  beneficial  effects  produced  by  the  internal  adminis- 
tration of  certain  remedies,  such  as  helonias,  caulophyl- 
lura,  cimicifuga,  nux  vomica,  etc.  With  reference  to  the 
use  of  pessaries,  he  thought  that  they  could  be  used,  not 
to  abuse  the  patient  and  set  up  inflammation,  but  as  tam- 
pons are  used  with  reference  to  special  conditions.  He 
believed  in  preparatory  treatment,  and,  when  the  patient 
had  reached  a  certain  point,  a  pessary  could  be  used  with 
advantage,  and  then  by  the  internal  administration  of 
remedies  the  dysmenorrhoea  could  be  overcome,  the 
leucorrhoea  relieved,  and  a  cure  would  follow  in  very 
many  cases. 

Dr.  a.  M.  Jacobus  had  seen  Dr.  Wylie  operate  upon 
a  large  number  of  cases  with  and  without  anaesthetics, 
and  had  seen  most  excellent  results  follow.  It  might  be 
better  to  resort  to  an  anaesthetic,  but  there  were  very 
many  cases  in  which  divulsion  could  be  practised  safely 
without  an  anaesthetic.  He  had  not  seen  a  patient  die 
after  divulsion,  and  he  had  seen  a  fatal  result  follow  very 
slight  dilatation  and  with  a  steel  sound.  He  thought 
that  after  the  patient  had  passed  two  or  three  years  of 
menstrual  life  without  being  relieved,  local  treatment 
should  be  begun  to  develop  the  uterus,  and  that  the 
patient  in  consequence  would  be  less  likely  to  require 
future  treatment  for  the  dysmenorrhoea  and  sterility. 

He  did  not  believe  that  there  was  a  single  anteflexion 
pessary  which  could  be  used  with  safety.  Of  all  the  in- 
struments which  he  had  employed,  or  seen  used,  he  pre- 
ferred that  used  by  Dr.  Wylie  to  any  other. 

With  regard  to  preparatory  treatment,  it  was  exceed- 
ingly important,  as  had  already  been  mentioned  by  Dr. 
Wylie.  He  thought  that  the  uterus  could  be  straightened 
up  considerably  by  means  of  the  tampon,  so  much  so 
that  the  divulsor  could  be  used  later  without  special 
difficulty. 

Dr,  WviiE,  in  closing  the  discussion,  said  that  he  had 
not  ha.d  a  single  case  of  cellulitis  occur  as  a  result  of 
operative  procedure  in  private  practice.  P'urther,  that 
he  had  no  special  faith  in  the  efficacy  of  remedies,  any  I 


more  than  that  they  might  improve  the  general  condition, 
and  in  that  way  help  a  weak  organ.  He  thought  prob- 
ably that  electricity  would  do  more  good  than  any  special 
remedies  which  might  be  administered  internally.  His 
faith  in  treating  symptoms  had  not  been  very  great  As 
to  the  use  of  pessaries,  he  was  satisfied  that  practically 
they  were  of  but  little  value,  although  he  was  aware  that 
some  of  our  very  best  men  employed  them  k  great  deal. 
The  great  trouble  was  that  when  a  gynecologist  was  thor- 
oughly interested  in  a  pessary  he  was  very  apt  to  make 
the  patient  fit  the  pessary  instead  of  the  pessary  fitting 
the  patient.  He  also  thought  that  glass  was  preferable  to 
hard  rubber  for  the  plugs  as  a  general  rule,  but  it  being  so 
much  more  difficult  to  obtain  he  had  substituted  the  hard 
rubber. 

The  reason  why  he  had  not  performed  Dr.  Sims' 
operation  was  because  he  had  found  that  by  slightly 
dilating  the  canal,  merely  enough  to  give  free  drainage, 
the  circulation  of  the  mucous  membrane  had  been  im- 
proved, and  then  by  the  application  of  remedies  the 
development  and  improvement  of  its  general  condition 
had  been  so  great  that  it  had  been  unnecessary  to  resort 
to  further  procedure.  He  had  not  found  it  necessary  to 
give  an  anaesthetic  unless  the  tissue  of  the  cervix  was 
very  hard. 

Dr.  Wylie's  reasons  for  not  cutting  the  os  internum 
was  because  he  looked  upon  it  very  much  as  a  sphincter, 
and  if  he  wished  to  remove  its  spasmodic  action  he  did 
not  cut  it,  but  dilated  it  a  little,  and  then  tore  the  tissues 
beneath  the  mucous  membrane.  Besides,  he  had  seen 
Dr.  Sims  cut  and  then  fail  to  introduce  the  glass  plug. 
Again,  when  he  found  that  he  could  accomplish  with  the 
divulsor  what  Dr.  Sims  had  endeavored  to  do  with  the 
knife  first  and  then  using  the  divulsor,  he  had  ceased  to 
use  the  knife.  The  ease  with  which  the  cervix  elongates 
had  caused  him  to  use  the  divulsor,  holding  the  cervix 
firmly  with  the  tenaculum. 

When  he  dilates,  as  he  called  it,  he  did  it  only  after  he 
became  perfectly  familiar  with  the  case,  had  given  it 
preparatory  treatment,  and  had  learned  the  complications. 
If  it  was  a  case  which  did  not  need  divulsion  then  he 
dilated.  He  resorted  to  divulsion  or  the  use  of  the  knife 
in  not  more  than  one  in  six,  perhaps  ten,  cases  where 
ten  years  ago  he  would  have  resorted  to  these  measures, 
simply  because  he  had  found  that  dilatation  would  ac- 
complish all  that  was  desired.  When  he  divulsed  it  was 
in  cases  in  which. he  had  resorted  first  to  preparatory 
treatment  and  then  to  dilatation,  and  finally  adopted 
divulsion  because  dilatation  did  not  effect  a  cure.  When 
he  divulses  he  generally  does  it  with  the  patient  under 
the  influence  sf  ether,  and  he  would  put  them  to  bed  and 
keep  them  there,  not  for  thtee  or  four  days,  but  for  two 
weeks.  He  never  allows  them  to  rise  from  the  bed  with 
the  stem  pessary  or  drainage-tube  in  position,  unless  it  is 
absolutely  necessary.  He  prefers,  as  a  rule,  to  have  the 
patient  wear  the  tube  after  one  menstruation ;  that  is, 
remove  it  during  menstruation  and  wear  it  afterward. 

Dr.  Sell  said  he  had  used  electricity,  and  had  found 
it  an  excellent  method  of  treatment.  He  would  further 
remark  that  dispensary  treatment  was  somewhat  different 
from  that  which  could  be  adopted  in  private  practice, 
and  thought  it  well  to  have  medicinal  means  to  resort  to 
independent  of  operative  procedure. 

The  Chairman  referred  to  one  point  which  he  had 
noticed  in  seeing  Dr.  Wylie  operate,  namely,  that  the 
pressure  made  upon  the  handles  of  the  divulsor  was 
intermittent,  and  that  the  instrument  was  turned  slightly 
at  short  intervals,  so  that  the  intra-uterine  pressure  was 
brought  to  bear  upon  all  parts  of  the  circumference  of  the 
cervical  canal. 

The  Swallowing  of  a  Shawl-pin. — Dr.  F.  W. 
Smith,  of  Syracuse,  N.  Y.,  writes  that  he  was  called  to 
see  a  woman  who  had  accidentally  swallowed  a  shawl-pin 
four  and  a  half  inches  long.  She  passed  it  by  rectum 
three  days  later,  without  suffering  any  inconvenience. 


696 


THE   MEDICAL   RECORD. 


[December  20,  1884, 


FIFTY-SEVENTH  MEETING  OF  GERMAN  NAT- 
URALISTS AND  PHYSICIANS, 

(Special  Report  for  Thk  Medical  Record.) 

A  LARGE  number  of  scientists  and  physicians  from  all 
parts  of  Germany  attended  the  fifty-seventh  annual  meet- 
ing of  the  Association,  at  Magdeburg.  They  were  greeted 
at  the  opening  session  by  Dr.  Gaehde,  who  delivered 
an  eloquent 

ADDRESS   OF   WELCOME. 

He  reviewed  briefly  the  history  of  the  Association, 
which  had  been  the  parent  of  many  other  illustrious 
bodies,  such  as  the  Surgical  Congress,  the  Congress  for 
Internal  Medicine,  the  Public  Health  Association,  etc., 
and  had  been  the  model  and  exciting  cause  of  many  of 
the  existing  international  congresses.  But  while,  the 
speaker  continued,  this  Association  might  indeed  be 
proud  of  her  children,  yet  it  should  be  remembered  that 
there  was  danger  to  her  own  strength  in  so  many  child- 
births.  He  counselled  his  hearers  therefore  to  stand  by 
their  old  mother  and  see  that  she  was  not  injured  by  the 
rivalry  of  her  progeny. 

THE   SECOND   ADDRESS 

was  by  Professor  Hochheim,  who  recalled  the  scientific 
glories  of  Magdeburg,  and  dwelt  upon  the  appropriate- 
ness of  its  selection  as  a  meeting-place  for  German  nat- 
uralists. The  first  medical  paper  was  by  Dr.  Rosen- 
BACH,  of  Gottingen,  and  was  upon  the 

RELATION    OF   MICRO-ORGANISMS   TO  WOUND    INFECTION. 

The  paper  was  a  most  interesting  one,  but  was  chiefly 
historical  and  critical  in  character,  and  contained  little 
that  is  not  already  known  upon  this  subject. 

The  next  paper  of  interest  to  physicians  was  by  Dr. 
Schwartz  upon  the 

RELATION   OF   HYGIENE   TO   PRACTICAL   MEDICINE. 

In  spite  of  the  great  advances  made  in  recent  years  in 
the  study  of  public  health  and  of  the  actual  results  al- 
ready obtained,  there  yet  remained  much,  very  much,  to 
do.  Hygienists  should  not  think  of  rest  untQ  the  last 
dark  and  unventilated  bed-chamber  had  been  destroyed, 
the  poor  man's  table  had  been  covered  with  nourishing 
and  unadulterated  food,  and  the  modern  scourge  of 
brandy  had  been  driven  back.  Unfortunately  but  little 
assistance  was  obtained  from  the  people  themselves  ;  it 
was  necessary  in  many  instances  to  iforce  them  to  be 
dean.  The  practising  physician  could  aid  the  hygienist 
greatly  by  seeking,  whenever  possible,  to  impress  upon 
his  patients  the  necessity  of  light,  ventilaljon,  and  per- 
sonal cleanliness. 

The  general  session  was  then  closed,  and  the  scientific 
labors  of  the  members  were  continued  in  the  several 
sections. 


SECTION  FOR  INTERNAL  MEDICINE. 

Professor   SeeligmIJller,   of  Halle,  presented   a 
communication  upon 

CARDIAC   DEBILITY. 

The  author  pictured  the  group  of  symptoms,  usually 
called  cardiac  neurasthenia,  as  follows :  After  a  period  of 
cardiac  disturbance,  palpitation,  pain  in  the  precordial 
region,  there  ensues  a  condition  of  general  weaJcness,  ex- 
pressed by  fatigue  after  slight  exertion,  insomnia,  forget- 
fulness  and  distraction,  and  a  depression  of  spirits.  At 
the  same  time,  despite  a  good  appetite,  sometimes  even 
boulimia,  there  is  a  falling  away  in  nutrition,  the  extrem- 
ities are  cold,  and  there  is  at  times  a  feeling  of  formica- 
tion. In  the  absence  of  any  organic  changes,  the  author 
was  inclined  to  refer  these  symptoms  to  anomalies  of  in- 
nervation, especially  as  they  occurred  most  frequently 
after  psychical  disturbances,  as  prolonged  sexual  excite- 
ment, severe  mental  labor,  combined  with  broken  rest. 


etc.  Rest,  warm  baths,  good  nourishing  food,  sea  or 
mountain  air,  and  quinine  in  small  doses  often  exerted  a 
favorable  effect. 

Dr.  Wagner  spoke  of  the  difficulty  of  diagnosis  at  the 
first  examination  in  these  cases.  In  all  heart  affections 
where  there  were  no  apparent  physical  disturbances, 
especially  in  those  of  advanced  years,  disease  of  the 
coronary  arteries  should  be  suspected.  The  speaker 
had  seen  cases  similar  to  those  described  by  the  author 
of  the  paper  in  women  who  had  borne  many  children  or 
who  suffered  from  certain  forms  of  uterine  disease.  This 
condition  was  caused  in  those  cases  by  an  overloading 
of  the  abdominal  organs  with  blood,  and  was  much  bene- 
fited by  wearing  an  abdominal  supporter. 

Professor  StrIJmpell,  of  Leipzig,  then  followed  with 
a  paper  on 

acute  encephalitis   of   CHILDHOOD. 

This  affection  resembles  in  nearly  every  particular  in- 
fantile spinal  paralysis.  It  occurs  with  greatest  frequency 
during  the  first  and  second  years  of  life,  seldom  later. 
There  is  usually  an  initial  stage  of  fever,  vomiting,  and 
convulsions,  followed  after  a  varying  period  by  paralysis. 
This  is  usually  nearly  complete  on  one  side  of  the  body. 
It  diminishes  after  a  time,  but  usually  leaves  more  or 
less  impairment  of  motion  and  of  growth  in  the  parts. 
Sometimes  the  affection  is  followed  by  motor  irritative 
symptoms,  such  as  epilepsy  or  athetosis,  or  by  impair- 
ment of  the  intellect  or  power  of  speech.  The  sensi- 
bility of  the  paralyzed  side  is  unaffected.  The  disease 
is  located  in  the  cortical  substance.  The  speaker  thought 
it  possible  that  poliencephalitis  and  poliomyelitis  might 
be  essentially  the  same  conditions,  the  disease  being 
located  now  in  the  gray  substance  of  the  cord  and  again 
in  the  corresponding  portion  of  the  encephalon.  In  an- 
swer to  a  point  raised  in  the  discussion  of  this  paper,  the 
author  said  that  he  made  a  diagnosis  of  acute  encephalitis 
only  in  those  cases  in  which  there  was  an  acute  initial 
stage  followed  by  a  stationary  cerebral  paralysis. 

Professor  Ebstein,  of  GSttingen,  followed  with  a 
communication  on 

THE  treatment  OF  TYPHOID   FEVER. 

His  conclusions  were  based  upon  an  experience  with  up- 
ward of  two  hundred  and  fifty  cases  seen  within  a  period 
of  seven  and  a  half  years,  and  were  as  follows  :  i.  The 
so-called  abortive  treatment  with  calomel  is  useful,  and 
therefore  to  be  recommended.  2.  A  treatment  based 
upon  etiological  grounds  is  impracticable,  and  the  man- 
agement of  the  disease  must  be  regulated  by  a  careful 
study  of  all  the  symptoms.  The  diet  requires  special 
attention.  3.  The  struggle  to  reduce  a  long-continued 
high  temperature  is  necessary  only  when  there  are 
threatening  symptoms  on  the  side  of  the  heart  or  nervous 
system  or  both,  or  when  the  fever  itself  reaches  a  dan- 
gerous height  4.  The  author's  experience  led  him  to 
assert  that  the  best  results  were  obtained  when  reliance 
was  not  placed  exclusively  upon  cold  baths  or  any  other 
so-called  strictly  antipyretic  method.  As  regards  an- 
tipyresis  from  drugs  he  had  met  with  success  in  the  use 
of  salicylate  of  soda. 

Professor  Koebner,  of  Berlin,  read  a  paper  on'the 

THERAPEUTIC  USE  OF  THE  LOCAL  ANTISYPHILITIC  ACTION         j 
OF  MERCURY. 

The  author  related  a  number  of  instances  showing  the 
value  of  mercury  locally  applied,  either  endermically  or 
hypodermically,  in  syphilitic  affections.  In  the  former 
case  the  mercur}'  acted  by  direct  absorption  through  the 
skin,  and  not  through  the  inhalation  of  mercurial  vapor, 
as  was  supposed  by  Kirchgasser.  The  speaker  urged  a 
more  general  employment  of  the  local  or  regional  ap- 
plication of  the  drug  in  connection  with  its  internal  ad- 
miniscration.  Whenever,  after  the  general  treatment  of 
syphilis,  there  remain  any  indurations  either  of  the  primary 
sore,  of  the  neighboring  glands,  or  of  any  of  the  tissues, 


December  20,  1884.] 


THE   MEDICAL  RECORD. 


697 


we  must  seek  to  cure  them  by  the  local  application  of 
mercury.  In  this  way  we  get  rid  of  future  centres  of  in- 
fection. Thus  the  occipital  and  cervical  mastoid  glands, 
which  are  usually  passed  by,  should  be  treated  for  a  long 
time  by  mercury  endermically,  the  applications  being  in- 
terrupted from  time  to  time  in  order  to  obviate  the  lia- 
bility to  inflammation  of  the  skin  and  consequent  impedi- 
ment to  absorption.  Of  course  in  such  cases  it  must 
first  be  determined  that  the  enlarged  glands  are  not  due 
to  some  local  irritation  within  their  lymphatic  district, 
as  for  example  when  the  glands  of  the  neck  are  enlarged 
by  reason  of  ulcerations  in  the  posterior  nasal  region. 
The  author,  after  trying  various  preparations,  found  that 
the  most  effectual  as  well  as  the  least  irritating  was 
freshly  prepared  ointment  of  the  gray  oxide. 

Dr.  Anfrecht,  of  Magdeburg,  read  a  paper  of  con- 
siderable length  upon 

CROUP  AND   DIPHTHERIA. 

He  regarded  these  two  affections  as  absolutely  identical. 
The  bacteria  were  the  same  in  either  case  and  the 
anatomical  differences  were  only  apparent.  In  croup 
the  membrane  is  separated  entire  and  expectorated  in 
the  form  of  a  tube,  while  in  the  faucial  affection  this  does 
not  happen.  In  diphtheria  the  mucous  membrane  is 
sometimes  the  seat  of  ulcers,  but  this,  the  speaker  main- 
tained, is  the  result  of  local  treatment.  It  has  been  stated 
that  the  membrane  in  the  pharynx  could  be  removed 
only  by  force,  while  that  in  the  larynx  often  became 
loosened  spontaneously,  but  Dr.  Anfrecht  said  that  the 
mistake  had  been  made  of  comparing  the  disease  in  the 
two  parts  at  different  stages  of  its  progress.  The  path- 
ological process  begins  in  an  exudation  of  fibrin  from 
the  blood-vessels  of  the  mucous  membrane  excited  by 
the  presence  of  the  bacteria.  This  fibrin  is  poured  out 
between  and  upon  the  epithelial  cells,  and  the  strength 
of  the  attachment  of  the  false  membrane  is  dependent 
upon  the  depth  to  which  th«  fibrin  has  penetrated  the 
epithelium  into  the  mucosa.  The  author  did  not  believe 
that  any  advantage  was  to  be  derived  from  a  local  treat- 
ment of  the  disease.  In  the  Magdeburg  Hospital  during 
the  past  four  years  two  hundred  and  twenty-five  cases  of 
diphtheria  had  been  treated,  and  but  one  death  had  oc- 
curred, and  that  was  in  a  case  in  which  a  local  treat- 
ment had  been  pursued.  Cold  compresses  were  ap- 
plied to  the  throat  and  a  gargle  of  chlorate  of  potassium 
was  used.  In  children  who  could  not  gargle,  small  doses 
of  the  drug  were  given  internally. 

Some  discussion  followed,  in  which  the  author's  views 
were  in  general  subscribed  to.  The  discussion  was  par- 
ticipated in  by  Drs.  Schwalbe,  Rindfleisch,  and  Ro- 

SENBACH. 

Professor  Ackerai ann  then  read  a  paper  on 
cirrhosis  of  the  liver. 

-  What  is  usually  understood  by  cirrhosis  of  the  liver, 
the  interstitial  hyperplasia  of  the  connective  tissue,  is, 
strictly  speaking,  not  the  morbid  process,  but  rather  the 
expression  of  a  secondary  salutary  process.  The  pri- 
mary process  is  nothing  else  than  a  necrosis  of  the  liver- 
cells  induced  by  the  presence  of  some  poisonous  sub- 
stance (alcohol,  phosphorus,  and  sometimes,  also,  it 
would  seem,  micro-organisms),  which  necrosis  seems  to 
be  accompanied  always  by  a  deposit  of  fat  in  the  cells. 
The  cells  are  destroyed,  and  then  follows  a  new  forma- 
tion of  connective  tissue  proceeding  from  the  interlobu- 
lar substance.  This  is  not  a  true  inflammation,  as  there 
is  no  hyperaemia  nor  exudation  of  white  corpuscles  from 
the  blood-vessels.  There  is,  however,  from  the  begin- 
ning a  new  growth  of  capillary  vessels.  But  the  inter- 
stitial new  growth  is  not  confined  to  a  development  of 
the  connective  tissue  and  blood-vessels,  but  embraces, 
also,  the  biliary  vessels.  This  is  a  conservative  measure, 
for  otherwise  the  excretion  of  bile  would  be  so  greatly 
impeded  as  to  destroy  the  life  of  the  patient.  The  exist- 
ence of  these  enlarged  blood-  and  bile-vessels  speaks 


against  the  view  that  the  atrophy  of  the  organ  is  due  to 
a  contraction  of  the  newly-formed  connective  tissue. 
The  atrophy  is  really  due  to  an  excess  of  cell-destraction 
over  the  new  production  of  interstitial  tissue.  When, 
however,  the  new  formation  is  in  excess  we  And  hyper- 
trophy of  the  liver,  a  condition  which  is  very  common, 
especially  at  the  commencement  of  the  disease.  There 
is  another  affection,  probably  identical  with  what  has 
been  called  cirrhosis  glabra^  in  which  there  is  hyper- 
trophy of  the  organ  due  to  a  diffuse  hyperplasia  of  the 
inter-  and  intra-cellular  connective  tissue.  This,  how- 
ever, has  nothing  in  common  with  ordinary  cirrhosis  of 
the  liver.  There  is  no  new  formation  of  blood-vessels, 
but  the  old  vessels  remain  normal  and  potent,  and  there 
is  in  consequence  no  ascites.  The  liver  remains  en- 
larged throughout  the  whole  course  of  the  disease,  and 
the  cells  become  atrophied  from  pressure  of  the  sur- 
rounding connective  tissue  and  not  from  a  primary  de- 
generative process. 

After  some  discussion  on  this  paper.  Dr.  JOrgens,  of 
Berlin,  presented  a  communication  upon  the 

ANATOMICAL   CHANGES    IN   ADDISON's   DISEASE. 

The  true  seat  of  the  disease  lies,  the  speaker  said,  in 
the  splanchnic  nerve-trunks.  The  degeneration  of  these 
nerves  may  occur  as  a  protopathic  affection.  In  such 
cases  there  is  a  simple  degeneration  of  the  supra-renal 
capsules  without  any  inflammatory  manifestations  in 
these  or  the  neighboring  organs.  A  deuteropathic  dis- 
ease of  the  splanchnic  nerve  following  a  primary  af- 
fection of  the  supra-renal  capsules  or  pancreas,  is  of 
much  more  frequent  occurrence.  But  in  all  cases  of  dis- 
ease of  the  supra-renal  capsules,  or  of  the  pancreas,  in 
which  there  is  no  bronzing  of  the  skin,  the  splanchnic 
nerve-trunks  are  found  intact. 


NEW  YORK  PATHOLOGICAL  SOCIETY. 
Stated  Meeting y  November  12,  1884. 

R.  E.  Van   Gieson,  M.D.,  Vice-President,   in  the 
Chair. 

PYELO-NEPHRITIS REMOVAL  OF  THE  KIDNEY  BY  ABDOMI- 
NAL SECTION. 

Dr.  H.  C.  Coe  presented  a  specimen  with  the  follow- 
ing history  :  The  patient  entered  the  Woman's  Hospital 
two  months  ago  with  a  tumor  about  the  size  of  the  foetal 
head  in  the  right  iliac  region,  and  rather  movable.  The 
tumor  would  disappear  at  intervals,  and  just  previous  to 
its  disappearance  the  patient  would  pass  large  quantities 
of  urine.  No  clue  to  the  character  of  the  disease  was 
given  by  the  examination  of  the  urine.  An  exploratory 
incision  was  made,  and  hydronephrosis  encountered,  and 
the  sac  was  removed.  The  patient  developed  peritonitis 
and  died  on  the  eighth  day.  After  the  operation  there 
was  never  more  than  a  slight  trace  of  albumen  and  a  few 
casts  in  the  urine. 

At  the  autopsy  it  was  found  that  the  stump  had  been 
secured,  but  the  ureter  had  slipped  and  was  blocked  up 
with  a  clot,  and  some  of  the  veins  had  also  retracted  be- 
neath the  peritoneum,  giving  rise  to  slight  hemorrhage. 
The  opposite  kidney  was  not  especially  abnormal. 

The  particular  point  of  interest  in  the  case  was  that 
two  days  before  death  the  woman  had  begun  to  menstru- 
ate, and  the  picture  of  the  pelvic  organs  was  very  inter- 
esting. The  uterus  was  retroflected,  and  all  the  pelvic 
organs  were  very  much  engorged  with  blood.  The  fim- 
briated extremities  of  the  Fallopian  tubes  resembled 
dilated  veins.  The  uterus  was  congested,  and  was  like  a 
sponge,  blood  flowing  freely  from  all  the  sinuses.  There 
was  a  corpus  luteum  in  one  of  the  ovaries. 

On  opening  the  uterus  the  mucous  membrane  was 
covered  with  a  thin  film,  which  could  be  raised  with  the 
forceps,  and  on  examination,  microscopically,  it  was 
found  to  be  a  layer  of  epithelial  cells  and  blood  under- 


698 


THE  MEDICAL  RECORD. 


[December  20, 1884, 


going  fatty  degeneration.  The  appearance  seemed  to 
confirm  the  theory  of  denudation  of  the  mucous  mem- 
brane in  menstruation. 

The  ureter  was  perfectly  normal,  as  also  was  the 
bladder.  There  was  no  mechanical  obstruction  between 
the  kidney  and  the  meatus  urinarius,  and  the  only  ex- 
planation which  he  was  able  to  give  concerning  the  cause 
of  the  hydronephrosis  was  that  there  was  merely  a  valve- 
like fold  at  the  ureter  as  it  opened  into  the  cyst. 

An  interesting  question  arose  ;  namely,  Was  there  any 
uraemic  element  in  the  case  ?  Twelve  hours  preceding 
death  the  patient  passed  only  about  two  ounces  of  urine, 
which  had  a  specific  gravity  of  1.020,  exhibited  a  trace  of 
albumen  and  a  few  casts,  but  no  blood. 

Dr.  Peabody  thought  that  too  much  stress  was  laid 
upon  urea  as  a  cause  of  uraemia,  for  the  condition 
known  as  uraemia  had  been  proven  to  be  independent  of 
any  retained  urea  in  the  economy.  He  thought  it  had 
been  shown  that  more  urea  can  be  injected  into  the  veins 
of  a  dog  than  any  human  being  can  retain  in  any  process 
of  disease  of  the  kidneys,  and  without  producing  any  such 
symptoms  as  are  passed  under  the  name  of  uraemia.  He 
did  not  think  that  urea  had  anything  to  do  with  uraemia. 
Dr.  Seguin  remarked  that  he  had  been  of  the  same 
opinion  as  Dr.  Peabody,  but  Grdhant  and  Quinquand  com- 
municated to  the  Acadetnie  des  Sciences^  on  August  25, 
1884,  the  results  of  recent  experiments  in  which  they 
produced  artificial  uraemia  by  the  hypodermic  injection 
of  urea  in  animals.  Perhaps,  therefore,  the  question  had 
not  yet  been  entirely  settled. 

Dr.  Wendt  thought  that  probably  Dr.  Peabody  went 
too  far  when  he  said  urea  plays  no  rdle  at  all  in  the  pro- 
duction of  uraemia.  He  thought  that  the  retention  of 
(urea  was  certainly  one  of  the  factors  in  the  production  of 
uraemia,  although  it  might  not  be  the  only  one. 

Dr.  Peabody  said  that  one  of  the  strong  points  in 
favor  of  the  theory  which  he  had  mentioned  was  the  fact 
that  urea  is  excreted  in  large  quantities  by  the  mucous 
membrane  of  the  intestines.  It  had  been  shown  that  by 
tying  the  ureters  in  roosters  the  urea,  being  unable  to 
make  its  exit  through  the  ureters,  is  found  in  large  quan- 
tities upon  die  mucous  membrane  of  the  alimentary 
canal,  and  the  conclusions  to  which  he  alluded  were 
based  upon  experiments  of  this  character.  It  would 
seem  to  be  irrational,  therefore,  that  urea  should  not  find 
its  way  out  of  the  human  economy  in  the  same  way  when 
it  can  do  so  in  other  animals,  and  that  it  can  da  so  in 
other  animals  has  been  proven  without  doubt 

ANESTHESIA  OF  THE  LEFT  TRIGEMINUS,  WITH  SO-CALLED 
TROPHIC   ULCERATION   OF  THE   HELIX. 

Dr.  Seguin  presented  a  patient,  a  man  forty  years  of 
age,  with  the  following  history :  He  had  had  partial 
anaesthesia  of  the  left  trigeminus,  left  occipitalis  major 
and  minor  nerves,  of  left  superficial  cervical  plexus,  and 
of  left  ulnar  and  median  distribution  for  a  year.  The 
external  ear  is  almost  totally  insensible.  A  few  weeks 
ago  a  small  "  blister"  appeared  on  the  left  external  ear, 
in  the  lower  third  of  the  fossa  of  the  helix.  This  has  be- 
come an  ulcer,  which  my  colleague  at  the  Manhattan 
Eye  and  Ear  Hospital,  Dr.  Pomeroy  (by  whose  courtesy 
he  had  seen  the  case)  designated  perichrondritis  and 
chrondritis  with  perforation.  There  are  no  signs  of 
ordinary  haematoma.  Under  a  dressing  with  bichloride 
of  mercury  lotion  the  ulcerative  process  has  been  arrested 
and  repair  is  progressing.  The  only  other  symptom  pre- 
sented by  the  patient  is  paralysis  of  the  left  vocal  cord, 
dating  back  six  years  to  an  attack  of  hoarseness.  The 
man  had  never  had  syphilis,  and  the  pathology  of  his 
anaesthesia  (which  certainly  is  not  hysterical  hemi-anaes- 
thesia)  was,  he  confessed,  quite  obscure.  From  the  ab- 
sence of  neuralgia  he  was  disposed  to  exclude  disease  of 
the  trunk  of  the  trigeminus  or  of  the  Gasserian  ganglia. 
The  ulcerations  of  the  cornea  (and  phthisis  bulbi)  co- 
existing with  trigeminal  anaesthesia  are  well  known,  though 
rare.    To  his  present  knowledge  this  case  was  unique. 


It  has  been  claimed  that  the  ulcerative  keratitis  of  tri- 
geminal anaesthesia,  and  the  peripheral  ulcerations  after 
sections  of  nerve-trunks  were  active  "  trophic  processes," 
the  direct  result  of  injury  to  **  trophic  "  nerve-fibres  con- 
tained  within  the  affected  nerve-trunks.  The  experi- 
ments of  von  Gudden  and  of  Snelling  have  shown  this 
theory  to  be  untenable  as  regards  the  trigeminus.  These 
experimenters  found  that  by  protecting  tihe  cornea  (Gud. 
den  by  artificial  ankylo-blepharon,  Snelling  by  sewing  a 
rabbit's  ear  over  the  eye)  there  might  be  complete  an«s. 
thesia  of  the  trigeminus  with  a  perfectly  clear,  healdiy 
eyeball.  Long  before  them,  however,  Brown-S6quard 
had  demonstrated  that  a  guinea-pig's  foot  might  be  kept 
indefinitely  healthy  after  section  of  the  sciatic,  by  care 
and  cleanliness.  The  conclusion  reached  by  these 
physiologists,  and  the  view  now  held  by  most  neurolo- 
gists was,  that  the  keratitis  or  ulcerations  of  the  foot  was 
traumatic  and  infectious,  the  anaesthesia  acting  only  as  a 
predisposing  cause  by  allowing  injury,  and  by  (in  the  case 
of  the  cornea)  preventing  the  normal  reflex  protecting 
movements. 

"  In  the  case  before  us  I  believe  that  the  ulceration  ' 
was  caused  by  scratching  and  subsequent  sepsis  of  a 
little  spot  on  the  helix,  the  analgesia  rendering  the  initial 
injury  and  subsequent  extension  of  disease  easy  and 
rapid.  In  other  words,  had  this  anaesthetic  ear  been 
fully  protected  from  injury  and  bacteria  it  would  have 
remained  sound.  The  healing  under  antiseptic  dressmg 
and  protection,  while  the  analgesia  persists,  is  a  proof  of 
this  view.  Let  me  add  that  I  know  of  one  fact  in  ex- 
perimental patholofly  somewhat  analogous  to  this  case. 
Years  ago  Brown-S6quard  showed  that  after  wounding 
one  of  the  restiform  bodies  of  the  medulla  in  guinea- 
pigs  the  external  ear  on  the  same  side  often  showed  gan- 
grenous ulceration  at  the  tip  and  edges.  May  it  not  he 
that  the  wound  in  the  medulla  extended  deeper  than  in- 
tended by  the  experimenters,  and  injured  the  ascending 
root  of  the  trigeminus,  thus  causing  anaesthesia  of  the 
affected  car?"  , 

Dk.  Levi  thought  it  was  not  absolutely  necessary  that 
injury  should  always  occur  in  order  that  ulceration  should 
exist,  because  when  the  nervous  supply  is  interfered  witii 
the  normal  power  of  repair  is  diminished.  He  did  not 
think  it  was  ever  pretended  that  by  doing  away  with  the 
nervous  supply  of  a  part  it  would  necessarily  die,  although 
it  had  much  less  blood  to  produce  that  reparative  process 
which  is  going  on  in  healthy  parts.  He  would  like  to  ask 
Dr.  Segum  whether  or  not  this  was  a  case  of  ulceration 
due  to  interference  with  the  nervous  supply  of  the  part. 

Dr.  Seguin  replied  that  the  anaesfiiesia  acted  indi- 
rectly as  a  predisposing  cause  only ;  that  in  the  anaes- 
thetic condition  injury  occurred  more  easily  because  of 
the  insensibility  of  the  patient  to  traumatic  influences? 

INGUINAL   KIDNEY   SIMULATING   HERNIA, 


Dr.  E.  C.  Wendt  presented  a  specimen  of  inguinal 
kidney  removed  from  the  body  of  a  woman  who  had 
died  of  various  senile  disorders  at  the  age  of  eighty-six. 
On  admission  to  the  St.  Francis  Hospital  she  affirmed 
positively  that  she  had  never  known  serious  illness  of 
any  kind.  She  had  for  a  number  of  years,  how  many 
she  could  not  say,  worn  a  truss  for  a  supposed  inguinal 
hernia.     She  died  soon  after  admission  to  the  hospital 

At  the  autopsy  the  right  kidney  was  found  connected 
by  a  firin  band  with  the  uterus,  and  was  also  situated  in 
the  inguinal  canal,  the  portion  protruding  externally  be- 
ing that  which  had  been  mistaken  for  a  hernia.  It  was 
evidently  a  congenital  condition,  and  the  kidney  had  no 
visible  pelvis.  The  ureter  was  very  much  shortened. 
The  kidney  on  the  opposite  side  showed  no  special 
change.  The  renal  artery  in  the  inguinal  kidney  did  not 
spring  from  the  abdominal  aorta ;  it  probably  arose  from 
the  iliac  artery.  There  was  no  suprarenal  capsule  con- 
nected with  the  kidney  removed  from  the  inguinal  ring, 
although  it  might  be  that  one  existed  above. 


December  20,  1884/J 


THE   MEDICAL  RECORD. 


699 


ENDARTERITIS   OBLITERANS. 

•  Dr/Peabody  presented  a  part  of  the  circle  of  Willis, 
showing  chiefly  the  basilar  artery,  together  with  some  of 
the  smaller  arteries  from  the  pia  mater,  removed  from 
the  body  of  a  man,  thirty-eight  years  of  age,  who  died 
with  peculiar  symptoms.  He  was  brought  into  the  New 
York  Hospital  November  ist,  unable  to  speak.  He  was 
bright  and  intelligent,  and  there  was  no  paralysis  of  mo- 
tion or  sensation  detected  at  the  time  of  admission. 
There  was  exaggerated  patellar  reflex  on  the  right  side. 
The  aphasia  was  distinctly  ataxic,  and  at  the  same  time 
the  patient  was  unable  to  move  the  tongue.  On  the  fol- 
lowing morning  there  was  complete  right  hemiplegia, 
the  patient  soon  became  unable  to  swallow,  was  nour- 
ished artificially,  developed  a  rise  of  temperature  in  the 
evening  after  two  days,  and  on  the  fourth  day  he  had  a 
succession  of  attacks  of  pulmonary  cedema,  in  one  of 
which  he  died.  The  urine  was  normal.  The  pulse  and 
respiration  were  normal  at  the  beginning,  but  toward  the 
end  they  increased  in  frequency.  At  the  time  of  death 
the  temperature  was  108°  F. 

At  the  autopsy  it  was  found  that  the  lumen  of  the 
vessels  at  the  base  of  the  brain,  especially  that  of  the 
basilar  artery,  was  very  much  interfered  with;  that  it 
was  due  to  a  growth  in  the  interior  of  the  vessels,  and 
exhibited  the  lesion  of  arteritis  obliterans.  Dr.  Peabody 
exhibited  microscopical  sections.  There  was  a  small 
spot  of  softening  in  the  left  corpora  striatum  and  internal 
capsule,  and  the  blood-vessels  in  these  regions,  upon 
both  sides,  were  distinctly  calcareous.  The  softening 
was  localized.  The  convolutions  were  all  normal.  The 
other  organs  throughout  the  body  were  substantially  nor- 
mal, except  old  fibrous  indurations  at  the  apex  of  each 
lung,  and  in  one  kidney  there  were  two  small,  old  ab- 
scesses. 

Dr.  Seguin  asked  concerning  the  condition  of  the  left 
Sylvian  artery. 

Dr.  Peabody  remarked  that  he  examined  this  artery 
with  special  care,  and  there  was  apparently  nothing 
wrong  with  reference  to  it. 

aneurism  of  the  arch  of  THE  AORTA — LOBAR  PNEU- 
MONIA. 

Dr.  Beverley  Robinson  presented  specimens  accom- 
panied by  the  following  history,  furnished  by  Dr.  J.  M. 
Mabbott,  of  St.  Luke's  Hospital :  Nicholas  B ,  fifty- 
three  years  of  age,  married,  native  of  Switzerland,  was 
admitted  to  the  hospital  July  14,  1884.  The  patient's 
family  history  was  negative.  He  had  a  venereal  sore  in 
1854,  not  followed  by  suppurating  bubo.  An  eruption 
appeared  upon  the  legs  a  few  months  afterward.  In  1857 
he  had  acute  rheumatism,  but  suffered  firom  no  cardiac 
symptoms  following  the  attack.  He  had  pleurisy  on  the 
right  side  one  year  ago.  He  has  indulged  freely  in  alco- 
holics and  tobacco.  During  his  stay  in  the  hospital  the 
patient  presented  symptoms  of  aneurism  of  the  arch  of 
the  aorta,  which  gave  rise  to  marked  difficulty  in  inspira- 
tion and  expiration,  but  no  other  evident  S3rmptoms,  so 
£ax  as  the  pulse  was  concerned,  and  no  paralysis  of  the 
vocal  cords.  On  the  evening  of  October  30th  the  pa- 
tient had  a  slight  chill,  followed  by  excessive  dyspnoea  and 
very  severe  pain  in  the  right  side.  On  the  following 
morning  his  temperature  was  103.5°  ^'j  pulse  126,  and 
the  pain  and  dyspnoea  continued.  The  breathing  was 
laborious  and  the  respirations  were  not  increased  in  fre- 
-quency.    The  patient  died  November  2d. 

At  the  autopsy  a  few  old  adhesions  were  found  over 
the  apex  of  the  left  lung.  The  middle  lobe  of  the  right 
lung  was  in  a  ^tate  of  red  hepatization,  and  the  pleura 
oovering  it  had  a  large  amount  of  recent  fibrin  upon  its 
surface.  The  upper  and  the  lower  lobes  of  the  right  lung, 
ajid  the  whole  left  lung,  were  in  a  condition  of  em- 
physema. 

The  heart  was  of  normal  size,  the  valves  competent, 
the  muscular  tissue  of  good  consistence.    The  aorta  was 


markedly  atheromatous,  especially  the  ascending  portion 
of  the  arch,  where  was  a  large  aneurismal  sac,  arising  from 
the  arch  just  at  the  origin  of  the  right  innominate  artery, 
extending  upward  and  forward,  and  pressing  against  and 
becoming  adherent  to  the  sternum.  It  was  as  large  as 
a  man's  fist,  and  contained  recent  clots.  There  was  a 
second  aneurismal  sac,  extending  backward  and  some- 
what to  the  left,  arising  just  below  the  origin  of  the  left 
carotid  and  subclavian  arteries.  The  innominate,  left 
common  carotid,  and  left  subclavian  arteries  were  ^so 
atheromatous. 

The  kidneys  and  liver  were  congested,  the  spleen  was 
soft  and  friable.  The  stomach  and  intestines  were  con- 
gested. 

From  a  clinical  point  of  view  the  case  was  interesting 
because  of  the  absence  of  the  radial  pulse,  the  presence 
of  two  considerable  aneurismal  sacs,  the  absence  of  any 
disturbance  of  the  larynx  although  the  trachea  was  con- 
siderably compressed.  Although  there  was  a  distinct  chill 
with  complaint  of  pain  in  the  right  side  nothing  was  found 
on  physical  examination  which  enabled  him  to  say  that 
pneumonia  or  pleurisy  existed.  There  was  no  sputum. 
The  primary  cause  of  death  was  aneurism ;  the  second- 
ary, pneumonia. 

Under  such  circumstances  Dr.  Robinson  thought  that 
one  could  only  presume  the  existence  of  the  pneumonic 
condition,  without  being  able  to  say  positively  that  it 
existed. 

TUBERCULAR   MENINGITIS— OLD   CATARRHAL   PHTHISIS. 

Dr.  Van  Gieson  presented  specimens  which  illustrated 
in  a  remarkable  degree  the  conservative  and  curative 
processes  of  nature,  unaided  by  the  physician's  skill  or 
art.  They  also  illustrated  the  aphorism  of  Niemeyer, 
that  the  greatest  danger  to  which  phthisical  subjects  are 
placed  is  that  of  becoming  tubercular.  They  were  re- 
moved from  the  body  of  a  man,  fifty  years  of  age,  whom 
he  first  saw  November  5th.  At  that  time  the  patient  was 
somewhat  actively  delirious,  without  special  elevation  of 
temperature.  On  .physical  examination  there  was  found 
evidence  of  solidification  of  the  apex  of  the  right  lung, 
and  he  was  somewhat  inclined  to  take  the  view  that  it 
was  a  case  of  low-grade  pneumonia.  At  the  next  visit 
the  delirium  had  increased,  and  Dr.  Van  Gieson  suc- 
ceeded in  obtaining  a  history,  which  was  that  the  patient 
had  had  vomiting  more  or  less  for  several  days,  intense 
headache,  and  had  had  a  staggering  gait.  The  man  be- 
came violent,  and  he  was  sent  to  SL  Catherine's  Hospital 
on  Thursday,  ancf  died  on  the  following  Monday  night. 
During  his  stay  in  the  hospital  there  was  no  elevation  of 
temperature.  He  died  in  a  state  of  partial  coma,  varied 
with  active  delirium.  At  the  autopsy  the  brain  presented 
the  typical  appearances  found  in  tubercular  meningitis. 
After  removing  the  lungs,  the  right  was  found  entirely 
adherent  posteriorly  as  far  down  as  the  diaphragm,  and 
was  so  firmly  attached  to  the  diaphragm  that  it  was  neces- 
sary to  cut  off  a  portion  of  that  muscle  before  it  could  be 
removed.  The  left  lung  was  adherent  to  the  chest-wall 
by  a  slight  band  posteriorly.  The  upper  portion  of  the 
right  lung  was  filled  with  calcified  material,  and  the  left 
lung  also  contained  more  or  less  of  calcified  nodules. 
The  patient  had  not  had  a  sick  day,  nor  lost  a  day's  work, 
during  the  last  thirteen  years.  Dr.  Van  Gieson  regarded 
it  as  probable  that  during  the  middle  period  of  this  man's 
life  he  had  what  had  been  called  catarrhal  phthisis,  from 
which  he  had  recovered.  He  would  ask  if  it  was  com- 
mon to  find,  post-mortem,  such  extensive  evidence  of 
previously  existing  destructive  disease  of  the  lungs  ? 

Dr.  Peabody  replied  that  he  had  not  had  an  oppor- 
tunity to  examine  the  specimens  presented  by  Dr.  Van 
Gieson,  but  he  did  not  think  it  was  common  to  find  ex* 
tensive  evidence  of  phthisis  which  had  been  latent  for 
years.  To  find  occasional  nodules  was  not  uncommon, 
and  it  was  sufficiently  common  also  to  be  unworthy  of 
special  consideration  to  find  extensive  pleuritic  adhesions. 

The  Society  then  went  into  executive  session.  . 


700 


THE   MEDICAL  RECORD. 


[December  20,  1884. 


^ovttspowSUnce. 


TRACHEOTOMY    IN   CROUP  AND    DIPH- 
THERIA. 

To  THB  Editor  op  Ths  Medical  Rbcord. 

Sir  :  In  The  Medical  Record  of  December  6th  I  am 
pleased  to  find  an  interesting  communication  from  Dr. 
S.  S.  Jones,  criticising  my  paper  on  "  Tracheotomy  in 
Croup  and  Diphtheria."     Permit  me  a  word  in  reply. 

Dr.  Jones  says  that  I  "  advocate  an  early  operation, 
giving  as  a  basis  for  my  argument  the  clinical  histories 
of  three  cases."  Herein  he  entirely  misapprehends  the 
purport  of  my  paper.  The  latter  was  written  after  hear- 
ing the  essay  of  Dr.  Winters,  which  is  so  replete  with 
historical  and  statistical  information  that  I  would  have 
deemed  it  absurd  to  dase  any  argument  by  which  I  de- 
sired to  second  his  views,  on  statistical  evidence  from  my 
own  personal  experience. 

Those  who  have  done  me  the  honor  to  read  my  con- 
tributions to  medical  literature  are  aware  of  the  fact  that 
I  am  in  the  habit  of  fortifying  my  views  by  large  and  un- 
assailable statistical  data  obtained  from  all  available 
sources.  The  latter  having  (in  this  case)  been  already 
furnished  by  Dr.  Winters,  I  desired  only  to  aid  in  com- 
bating the  unreasonable  prejudice  which  seems  to  exist 
against  tracheotomy  among  physicians  as  well  as  laymen. 
With  this  view  I  cited  three  recent  cases,  as  an  iUustra- 
iion  that  <'  one  successful  tracheotomy  (in  this  instance 
performed  by  Dr.  A.  Jacobi)  would  do  more  to  neu- 
tralize groundless  apprehension  than  all  the  statistics,'' 
eta 

As  "  two  of  these  cases  were  circumstanced  precisely 
alike,  being  of  the  same  age  and  in  the  same  social 
grade,"  and  occurring  in  the  same  epidemic,  I  utilized 
them  to  contrast  the  result  of  an  early  operation  with 
that  of  a  late  one.  If  I  had  wished  to  enter  into  details  I 
might  have  stated  that  in  this  epidemic  of  laryngeal  diph- 
theria, which  swept  away  quite  a  number  of  children  (I 
have  not  yet  obtained  the  exact  figures  from  the  attend- 
ants, being  myself  only  called  in  council  in  a  few  cases), 
the  only  recovery  was  in  the  case  I  cited  as  being  tracheal- 
omized,  and  I  might  have  furnished  other  details,  which  I 
reserve  for  future  discussion.  It  was  not  my  intent  to 
write  an  essay,  but  simply  to  arouse  an  interest  in  the 
discussion,  and  I  am  glad  that  this  result  has  been  at- 
tained. 

Dr.  Jones  has  also  misunderstood  my  position  with  ref- 
erence to  an  early  operation.  If  he  will  read  my  paper 
carefully  he  will  find  that  I  say  "  it  is  the  duty  of  the 
attendant  to  operate  early  in  the  first  indication  of  abid- 
ing laryngeal  stenosis."  Cases  may,  as  he  says,  appear 
"  threatened  by  asphyxia  and  yet  recover."  It  is  for 
the  attendant  to  decide  whether  the  stenosis  is  abiding 
or  only  paroxysmal.  I  have  myself  watched  a  case  of 
laryngeal  stenosis  an  entire  night,  while  instruments  and 
table  were  in  readiness  for  tracheotomy,  which  was  found 
unnecessary  when  the  morning  dawned. 

Dr.  Jones  says  :  "  I  cannot  but  dissent  from  the  con- 
clusion of  the  author,  because  I  believe  that  if  tracheot- 
omy were  generally  performed  early  in  croup  many 
children  would  be  unnecessarily  subjected  to  it,  and  cures 
which  would  have  been  either  spontaneous  or  the  result  of 
medical  treatment  attributed  to  it "  (italics  mine). 

To  one  who,  like  Dr.  Jones,  is  *'  actuated  in  operat- 
ing more  by  the  desire  to  relieve  the  patient,  if  only 
temporarily,  than  inspired  by  any  great  hope  of  saving 
life,"  the  fear  that  tracheotomy  may  get  the  credit  of 
a  cure  without  deserving  it,  may  seem  an  insuperable  ob- 
jection to  the  operation.  But  if  I  mistake  not  the  tem- 
per of  most  practitioners,  such  an  argument  would  not  be 
regarded  a  moment  when  a  human  life  is  to  be  saved. 
Nor  would  Dr.  Jones*  statement  that  deaths  are  some- 
times attributable,  "worst  of  all,  to  the  accidental  stop- 


ping of  the  tube,"  weigh  against  the  operation,  carefully 
done  and  watched  over  in  the  after-treatment. 

It  is  just  this  prejudice  against  tracheotomy  which  has  < 
impaired  its  usefulness,  and  to  dispel  which  Dr.  Winters' 
paper  and  my  brief  contribution  have  been  written. 
There  exists  no  more  baneful  nor  more  universal  enor 
among  medical  men,  especially  when  our  experience  is 
not  large,  than  the  habit  of  making  deductions  from  that 
small  experience  for  our  own  guidance.  It  would  surely 
be  far  more  rational  and  just  to  temper  our  egotism  by 
utilizing  as  guides  the  published  experience  obtained  by 
others  from  large  clinical  material— //kj  our  own  experi  j 
ence.  Under  such  treatment  Dr.  Jones*  seven  tracheot- 
omies with  one  successful  result,  would  lead  him  to  recog. 
nize  that  he  is  in  error,  when  he  regards  his  own  experience 
in  tracheotomy  as  compared  with  the  results  of  non- 
operative  management  as  unfavorable.  Dr.  J.  Lewis 
Smith  has  told  us  that,  according  to  his  experience  and 
observations,  about  one  in  eight  recover  by  inhalation, 
which  he  regards  as  the  best  treatment.  Now,  Dr.  Jones 
has  had  the  good  fortune  to  save  one  in  seven  tracheot- 
omied  cases,  even  when  he  treated  the  operation  in  a 
kind  of  "  stepmotherly  "  manner.  Hence  he  should  be 
encouraged  by  this  comparison  to  look  with  more  favor  i 
upon  the  operation,  especially  if  he  will  study  withut 
prejudice,  the  statistics,  '*from  which  it  appeared  that 
from  twelve  to  thirty-nine  per  cent,  had  been  saved  by 
the  operation,  and,  under  improved  methods  of  operating, 
it  might  be  expected  to  save  one  in  three  by  tracheotomy" 
(J.  Lewis  Smith).  Indeed,  this  favorable  result  is  nearly 
attained  in  the  aggregate  of  the  cases  referred  to  in  Dr. 
Jones'  letter  and  my  paper  ;  for  here  we  have  three  rt- 
cover ies  in  eleven  cases  (Dr.  Jones  one,  Dr.  Jacobi  one, 
and  Dr.  Baruch  one).  Dr.  Jones  recommends  "equal 
parts  of  powdered  alum  and  sulphur  to  be  blown  into  the 
throat  at  the  moment  of  deep  inspiration  as  often  as 
asphyxia  threatens."  This  treatment  will,  I  think,  find 
little  favor  with  pracdtioners.  "The  child,**  says  Dr 
Jones,  "  struggled  through  the  next  thirty-six  hours^  ex- 
pelling shreds  of  membrane  after  the  insufflation  at  fre- 
quent intervals,  until  at  length  on  the  fourth  day^  the 
respiration,  though  somewhat  difficulty  was  much  deeper 
and  freer'*  (italics  mine).  Aside  from  the  apparent 
cruelty  of  this  procedure,  no  physician  bearing  in  mind 
the  fact  that  in  diphtheria  there  is  great  danger  fi-om 
heart-failure,  would  have  the  temerity  to  subject  the 
little  sufferer  to  the  struggle  incident  to  this  suffocating 
process,  <*  used,  if  used  at  all,  freely  and  energetically." 

One  of  the  chief  advantages  of  tracheotomy  in  laryn- 
geal stenosis,  and  one  which  has  not  been  sufficiently 
emphasized,  is  the  tranquil  condition  of  the  patient  re- 
sulting from  the  majority  of  operations.  With  proper 
care  of  the  tube  and  skilled  supervision  of  the  after- 
management,  the  little  sufferer  is  at  once  transposed 
from  "  a  bed  of  thorns  to  a  bed  of  roses,'*  as  it  were. 
The  natural  (not  carbonic  oxide)  sleep,  the  renewed 
facility  of  taking  nutriment,  medicines,  and  stimulants, 
the  vitalizing  influence  of  free  ingress  of  oxygen  to  the 
lungs — ^all  these  conspire  to  change  the  whole  aspect  of 
the  case.  No  statistics  are  required  to  demonstrate  this 
fact ;  it  is  within  the  experience  of  most  practitioners. 

Let  each  one  divest  himself  of  all  prejudice  at  this 
time,  scan  all  the  arguments  and  statistics  brought  for- 
ward in  the  discussion  of  last  March,  and  in  the  present 
renewal,  then  add  his  own  experience  without  fear  and 
without  favor.  The  result  will  be  a  triumphant  vindica- 
tion of  the  life-saving  properties  of  tracheotomy,  when 
performed  as  soon  as  abiding  laryngeal  stenosis  is  rec- 
ognized, and  carefully  watched  in  the  after-treatment. 

Simon  Baruch,  M.D. 

43  East  Fifty-ninth  Stxbxt,  December  7, 1884. 


The  Most  Powerful  Antisuppurative,  according 
to  Trastour,  is  Lugol's  solution,  or  iodide  of  calcium. 
He  gives  the  former  in  doses  of  3  iij.-  3  iv.  daily. 


The   Medical   Record 

A   Weekly  Journal  of  Medicine  and  Surgery 


Vol.  26,  No.  26 


New  York,  December  27,  1884 


Whole  No.  738 


^J^dflitmt  %xX\tVtz. 


SPINAL  DISEASE  AND  SPINAL  CURVATURK* 
By  MEIGS  CASE,  M.D., 

LATB  SURGEO^^  FORTY-THIRD  NBW  YORK  VOLUNTBBR8  ;     LATB  PRBSIDBNT  OTSBGO 
COUNTY,   N.Y.,  MWJICAL  SOOBTV. 

In  the  production  of  diseases  or  deformities  of  the  spine 
mechanical  causes  predominate.  It  is  nearly  safe  to 
say  that  they  are  all  due  to  some  mechanical  cause. 
Any  undue  shake,  twist,  or  forcible  flexion  of  the  eighty 
articulations  of  the  spine  ;  any  direct  or  indirect  violence 
or  contra-coup  ;  any  bruise  or  extravasation  into  the  com- 
plicated bony  or  intervertebral  tissues,  any  disturbance 
or  dislocation  upon  each  other  of  the  seven  distinct  cen- 
tres of  ossification  that  compose  each  vertebra  in  the 
young,  may  be  an  original  cause  of  disease  or  curvature. 

The  precise  location  of  the  injury,  and  the  consecutive 
effect  of  the  weight  of  the  superincumbent  parts,  from 
which  there  is  no  escape  without  extension,  determine 
the  character  and  form  of  disintegration  or  deflexion 
which  ensue  by  slow  inflammatory  processes  superin- 
duced by  continual  repetitions  and  aggravations  of  the 
original  hurt.  To  this  is  added  as  the  disease  advances 
and  pain  is  developed  the  well-known  destructive  influ- 
ence of  muscular  spasm  or  unremitting  vise-like  com- 
pression, produced  by  nature's  instinctive  effort  ta  limit 
motion  and  thus  allay  friction  of  the  diseased  joint. 
This  effect  is  not  unlike  the  process  by  which  bedsores 
are  produced  by  arrest  of  circulation. 

Incessant  and  unvarying  pressure,  by  its  destructive 
strangulation  of  nutrient  vessels,  completes  with  abscess 
the  disaster  of  Potf  s  disease,  ' 

The  mechanical  causes  of  lateral  curvature  are  natu- 
rally those  that  impair  muscular  counterpoise.  Any  local 
debility  or  enforced  unnatural  attitude  aided  by  gravita- 
tion may  give  rise  to  all  the  varieties  and  exaggerations 
of  this  deformity.  "Any  constant  pressure  on  the  spine 
will  produce  curvature,'*  according  to  Von  Swieten. 
A  trifling  deviation  at  the  beginning,  perfectly  curable 
by  a  few  weeks'  treatment,  becomes,  when  neglected,  a 
serious  calamity,  "  painfully  embittering  after  life,"  "  for 
of  all  the  varieties  of  deformity  none  so  greatly  detract 
from  the  beauty  of  the  human  carriage  as  distortion  of 
the  spine." 

It  therefore  follows  that  every  aberration  or  injury  to 
the  spine  should  be  considered  worthy  of  |minute  atten- 
tion and  subjected  to  careful  treatment  at  the  earliest 
possible  moment. 

The  unfortunate  fact  that  not  one  case  of  spine  dis- 
ease in  a  thousand  is  detected  and  treated  as  such  from 
the  beginning  is  very  discreditable. 

Parents  discover  this  and  say  :  ''  The  doctors  cannot 
decide  what  is  the  difficulty."  Mistaken  treatments  for 
malaria,  rheumatism,  gastrodynia,  colic,  indigestion,  grow- 
ing pains,  and  worms,  usually  employ  very  considerable 
time  before  the  serious  character  and  injurious  possibili- 
ties of  the  prime  injury  are  plainly  diagnosticated  by  the 
occurrence  of  actual  deformity. 

This  period  of  doubt  and  incertitude  would  be  abol- 
ished with  the  deformity  it  perpetuates,  if  an  acceptable, 
convenient,  and  ever-ready  means  of  treatment  of  ac- 
knowledged efficacy  and  utility  were  at  hand ;  but  if  the 


^  An  addrtM  ddiTered  befinre't 


daon  County,  N.  J.,|MediG«l  Society. 


disease  remains  undetected  and  untreated  until  deformity 
is  reached,  a  great  opportunity  has  been  lost,  for  preven* 
tion  here,  as  elsewhere,  is  better  than  cure. 

It  is  evident,  however,  that  any  treatment  sufficiently 
well  devised  to  relieve,  modify,  or  benefit  the  most  ad- 
vanced stages  of  these  diseases  ought  to  cure,  when  early 
and  properly  applied  in  the  forming  stage. 

This  brings  us  to  the  consideration  of ,  the  means  of 
treatment  in  use  by  the  application  of  some. of  the  forms 
of  so-called  "rest." 

Among  these  are  **  fixation"  and  "absolute  immobili- 
ty" splints,  terms  which  sufficiently  describe  popular 
treatments  by  "braces"  and  "jackets." 

The  number  and  variety  of  these  devices,  all  intended 
by  lateral  compression,  or  crutches  resting  on  the  hips, 
to  support  the  weight  of  superincumbent  parts,  is  appall- 
ing. Their  production  has  become  "  a  great  American 
industry."  Some  of  them  like  the  "jury-mast,"  contain 
the  merest  suggestion  of  spinal  extension,  upon  which 
alone  valid  claims  to  favor  could  rightfully  be  based,  but 
accomplish  it  so  imperfectly  and  indifferently,  by  means 
so  disadvantageous  and  indirect,  as  to  have  compelled 
me  to  adopt  a  more  simple  and  effective  method  by 
which  "  elastic  extension"  is  furnished  without  compro- 
mising entire  freedom  of  action. 

My  apparatus  consists  of  a  four-wheeled  carriage,  with 
parallel  bars  for  the  hands,  surmounted  by  two  upright 
spars  and  cross-piece,  from  which  depends  a  powerful 
spiral  spring,  and  below  this  a  swivelled  bar,  carrying  suit- 
able soft  leather  suspensory  rests  to  embrace  the  chin 
and  occiput.  The  elevation  is  regulated  by  a  screw,  and 
can  be  increased  as  tolerance  is  manifested  in  the  use  of 
the  apparatus  and  the  patient  gains  in  height. 

In  dorsal  and  lumbar  curvature,  a  corset  or  waist  sus- 
pension is  added,  arranged  with  large  wood  rings,  through 
which  the  arms  are  passed,  so  as  to  avoid  any  of  lifting 
the  shoulders  or  limitation  of  their  movements  in  any 
direction. 

The  patient  can  turn  around  and  move  freely  to  and 
fro,  walking  or  running  in  the  suspension  at  will,  and  a 
pleasing  change  of  position  is  accomplished  by  an  adjust- 
able seat.  Action  or  continual  change  of  position  is 
thus  rendered  not  only  possible,  but  agreeable  and  pleas- 
urable. 

The  proper  adjustment  of  the  suspension  is  directed 
by  the  patients  themselves. 

The  spring  accompanies  every  movement  and  is  strong 
enough  to  support  the  entire  weight  when  required.  Thus 
all  restriction  is  practically  done  away  with.  I  have  found 
it  useful  in  all  cases  where  spinal  extension  is  indicated, 
and  those  comprise  nearly  all  spinal  affections,  not  only 
Pott's  disease  and  all  of  the  forms  of  lateral  curvature, 
but  muscular  debility  and  chronic  fatigue  of  the  erector 
muscles,  with  or  without  paraplegia  or  spinal  irritation. 

H.  Heather  Bigg,*  the  celebrated  English  orthopraxist, 
sufficiently  illustrates  the  requirements  of  treatment  in 
these  cases  when  he  deplores  the  fact  that  "  every  form 
of  instrument  with  which  I  was  aquainted  before  I  de- 
signed these  (a  new  brace  with  rubber  attachments) 
limited  or  entirely  suspended  muscular  motion." 

He  previously  alludes  to  "M^  necessity  that  appeared 
to  exist  for  such  an  application  of  mechanical  power  to 
the  treatment  of  spinal  curvature  as  would  admit  of  com- 
plete bodily  freedom.*'  In  this  we  claim  to  have  suc- 
ceeded, for  the  apparatus  not  only  does  not  impede  but 

t>  H.  H.  Bigg  :  Orthroprazy,  page  a8a«    London,  1877. 


702 


THE   MEDICAL  RECORD. 


[December  27, 1884. 


greatly  facilitates  movement,  and  fortunately  does  not 
add  weight  to  a  patient  already  orerweighted  by  disease. 

A  plain  reason  why  the  traction  is  more  efficient 
than  any  other  is  that  it  is  not  monotonous,  but  changes 
with  every  movement,  from  a  few  pounds  to  the  entire 
weight. 

The  apparatus  furnishes  appropriately  the  most  agree- 
able and  beneficial  "  spinal  exercise "  for  treatment  of 
lateral  curvature.  It  is  only  by  suitable  extension  that 
the  retraction  and  wasting  of  the  spinal  ligaments  and 
muscles,  the  absorption  of  the  vertebral  tissue,  the  for- 
mation of  antagonizing  or  compensatory  curves,  or  the 
lateral  horizontal  movement  known  as  **  rotation "  can 
be  prevented  or  permanently  corrected. 

It  is  thus  more  "  according  to  nature "  than  any  form 
of  straitjacket,  brace,  or  "absolute  immobility  splint" 
with  which  I  am  acquainted.  Observing  a  patient  with 
Pott's  disease  you  will  notice  that  by  trying  to  support 
the  weight  of  the  head  on  his  hand,  or  leaning  across  his 
mother's  lap,  or  sitting  with  both  hands  resting  on  the 
chair,  or  walking  with  a  stiff  and  unnatural  gait  with  both 
hands  on  his  knees,  he  is  constantly  furnishing  unmistak- 
ably the  indications  for  treatment  by  extension. 

The  principal  joints  of  the  lower  limbs  are  half  bent, 
to  prevent  vertebral  concussion,  the  projecting  chin  and 
elevated  shoulders  are  held  stiffly  by  rigid  spasm  of  all 
the  dorsal  and  intercostal  muscles. 

Movements  are  executed  with  automatic  precision. 
Stooping  is  impossible  in  the  ordinary  manner  and  is  ac- 
complished by  bending  the  hips,  then  the  knees,  then 
sliding  awkwardly  to  the  floor. 

The  muscular  movements  of  the  heart  are  directly  in- 
terfered with  by  the  unnatural  spasmodic  rigidity  of  the 
thoracic  compression.  It  flutters  like  a  bird  in  its  cage, 
while  the  respiration,  equally  embarrassed,  is  short  and 
grunting.  Cyanosis  and  the  peculiar  facial  expression 
are  thus  produced.  It  is  suggestive  that  no  child  asks 
its  nurse  to  compress  its  chest  for  temporary  rest,  or  other 
reason,  but  if  you  tentatively  lift  the  head  by  placing  the 
"  elastic  extension  "  of  your  hands  under  the  chin  and 
occiput,  a  smile  of  grateful  relief  comes  over  the  sufferer's 
face,  and  he  says,  **  That  feels  good." 

Now  if  you  take  the  little  patient  at  his  word,  and  put 
him  in  this  apparatus,  you  will  find  that  he  will  indicate 
unmistakably  its  relief.  He  will  breathe  easier,  the  char- 
acteristic facial  expression  of  the  hunchback  will  disap- 
pear, and  all  bodily  movements  %ill  be  better  performed. 
Soon  his  height  will  increase  ;  and  by  pursuing  a  life  of 
constant  activity  and  exercise,  a  cure  or  a  most  gratifying 
improvement  in  vigor  and  form  will  take  place. 

What  is  "  rest"  for  the  spine?  I  define  it  as  a  com- 
plete reversal  of  the  ordinary  function  of  the  spine  by 
active  extension. 

A  treatment  by  traction  and  free  motion  is  thus  di- 
rectly indicated  and  is  far  more  curative  and  beneficial  to 
the  spine  itself  than  inaction  or  recumbency.  A  healthy 
resistance  is  imparted  to  the  entire  section,  effectually 
preventing  abscess,  and  when  it  has  occurred,  greatly 
promoting  resolution  and  the  processes  of  repair. 

The  injustice  to  sound  articulations,  which  involves 
them  in  treatment  and  pseudo-anchylosis  intended  for 
disease  is  avoided. 

If  "rest"  can  be  accomplished  without  interfering  with 
the  normal  motion  indispensably  essential  to  the  health 
of  joints,  so  much  the  better.  A  joint  deprived  of  motion 
is  already  diseased ;  condemned  to  inaction  and  loss  of 
function;  its  "occupation  gone,"  the  conditions  most 
favorable  to  abscess  and  disintegration  are  filled.  The 
demand  of  the  joints  for  motion  is  as  incessant  and  in- 
satiate as  that  of  the  lungs  for  air,  or  the  heart  for  blood. 
•*  Immobility,"  "constant fixation,"  any  form  of  "motion- 
less restriction,"  or  rigid  extension  is  not  rest. 

The  governing  principle  of  this  treatment  is  too  well 
known  in  its  application  to  analogous  diseases  of  other 
joints  to  require  any  extended  comment 

The  researches  of  Henry  G.  Davis,  whose  little  work 


on  conservative  surgery  is  one  of  the  roost  original,  sub 
gestive,  and  instructive  that  the  practical  surgeon  c^ 
place  upon  his  table,  were  the  first  to  show  the  universal- 
ity of  the  great  curative  principle  of  "elastic  extension'" 
in  the  treatment  of  all  diseased  joints.  He  **  was  the  first 
to  point  out,  as  an  always  present  factor  in  their  destruc- 
tion, the  existence  of  unremitting;  pressure  as  effected  by 
contraction  of  the  muscles  passing  over  the  joints  cans- 
ing  constant  forcible  apposition  of  the  surfaces  within  the 
joint."  He  gave  to  the  world  the  principle  of  **  elastic 
extension  "  and  applied  it  indiscriminately  to  the  spine 
hip,  knee,  or  ankle. 

In  my  opinion  this  discovery  entitles  him  to  atf  emi- 
nence not  less  than  that  accorded  to  the  discoverers  of 
anaesthesia  or  vaccination.  I  fully  believe  that  if  his 
humane  suggestions  could  be  practically  carried  out,  by 
the  instant  application  of  "  elastic  extension  "  in  all  ap- 
propriate cases,  the  hideous  deformities  arising  from  the 
causes  under  consideration  would  exhibit  a  curability  at 
variance  with  the  professional  belief. 

His  apparatus  for  hip  extension  and  suggestions  for 
treatment  have  been  almost  universally  adopted  by  the 
profession,  relieving  as  they  do  all  pain  and  spasm,  and 
permitting  free  motion  and  recovery  without  deformity. 

"  Elastic  extension  and  motion  "  have  robbed  this  dis- 
ease of  most  of  its  "  terrors,"  as  Davis  said  they  would. 
The  terrors  of  joint  disease  are  pain  and  deformity. 

"  As  a  profession  we  are  not  sufficiently  aware  of  the 
ultimate  eflect  of  continued  suflering,  of  how  many  lives 
are  lost  that  might  have  been  saved  had  their  surround- 
ings been  so  arranged  as  to  enable  the  patient  to  rest 
quietly,  and  to  move  free  from  every  irritating  cause ;  loss 
of  sleep  and  rest,  loss  of  appetite  and  nutrition ;  them- 
selves sufficient  to  destroy  life  "  (Davis). 

In  regard  to  the  spine,  he  says :  "  The  rational  way  to 
treat  curvatures  is  to  relieve  the  spine  of  the  weight  of 
the  head  and  shoulders."  But  the  application  of  the 
principle  of  "  elastic  extension  "  to  the  treatment  of  the 
diseases  of  the  spine  has  never  (as  in  the  case  of  hip- 
joint  disease)  passed  into  general  medical  practice.  The 
mechanician  and  specialist  "  hold  the  fort "  with  innumcr- 
able  restrictive  appliances  fastened  to  the  wretched  bodies 
of  these  patients,  illustrating  all  the  evils  of  an  ingenious 
but  empirical  system  of  mechanical  therapeutics  in  all 
the  varieties  of  worthless  simplicity,  cumbrous  complex- 
ity, and  injurious  restriction ;  in  faet,  the  treatment  is 
practically  unchanged  since  the  Hippocrates  of  France, 
Ambrose  Par6,  in  the  sixteenth  century,  first  suggested 
the  "  repouss6  jacket "  or  body  splint,  beaten  out  of  thin 
metal  and  carefully  fitted  by  the  skilful  armourers  of  those 
days.  Park's  breast  and  back  plate  below  sufficiendy 
illustrate  the  antiquity  of  restriction.^ 


It  is  strange  "  that  this  earliest  piece  of  mechanism  in- 
tended to  be  worn  for  the  relief  of  a  distorted  spine" 
was  lighter,  better  ventilated,  less  cumbrous,  thinner, 
more  easily  removable  and  adjustable  than  the  modem 
jacket  of  plaster-of-Paris,  while  it  answers  every  require- 
ment of  restriction  as  fully  as  can  be  desired.  The  com- 
plicated arrangement  of  modern  braces  and  jackets,  and 

'  From  the  *'  works  of  that  famous  chinurarion,  AmtmMe  Parey,  translated  ootfit 
Latine,  and  compared  with  the  French  by  Thomas  Johnson.  London  :  Printed  bf 
£.  C,  and  are  sold  by  John  Qarke,  at  Mercer'slChappelJ,  in  Cheapside  Kcatc 
ye  Great  Conduit.    1665." 


December  27,  1884.] 


THE   MEDICAL  RECORD. 


703 


the  constant  changes  required  to  keep  these  defective  ap- 
pliances in  order,  as'  well  as  their  notorious  inutility  and 
danger,  have  compelled  careful  physicians  who  wish  to 
retain  the  perfect  confidence  of  families  to  abandon  the 
"  responsibility  "  of  treatment  of  these  cases  by  methods 
in  vogue;  but  it  has  been  readily  sought  and  assumed 
by  the  specialist.  An  imperfect  appliance  always  needs 
a  good  deal  of  engineering  to  supplement  radical  de- 
fects which  a  good  apparatus  does  not  require.  Enu- 
meration of  the  appliances  restricting  and  encompassing 
the  entire  trunk  in  abortive  attempts  to  give  support  to 
the  spine  is  simply  impossible.  Their  great  number 
proves  their  inutility.  But  the  most  eminent  recent 
authorities  refer  to  them  all  as  follows :  "  Mechanical 
contrivances  are  much  vaunted,  and  are  much  employed. 
I  confess,  however,  to  having  little  faith  in  their  value  as 
curative  agents.  They  tend  to  cause  atrophy  of  the  mus- 
cles  instead  of  strengthening  them  and  thus  to  make  the 
deformity  a  permanent  one  "  (Bryant). 

"  All  the  instruments  at  present  so  generally  used, 
making  direct  lateral  pressure  on  the  convexity  of  the 
curves,  must  tend  to  increase  the  mischief "  ("  Lectures 
on  the  Pathology  and  Treatment  of  Lateral  and  other 
Forms  of  Curvature."  Second  edition,  page  296.  Will- 
iam Adams,  London). 

But  the  principle  of  **  elastic  extension  "  is  just  as  im- 
mutable as  it  is  curative.  It  is  just  as  appropriate  for 
one  joint  as  it  is  for  another,  and  by  its  thorough  applica- 
tion, unembarrassed  by  restriction,  not  only  all  pain  and 
soreness  is  relieved,  but  every  indication  for  mechanical 
treatment  is  fulfilled,  without  peril  or  discomfort.  Every 
indispensable  condition  and  prerequisite  to  recovery  is 
thus  furnished  in  a  direct  and  simple  manner. 

It  is  evident  that  if  any  improvement  can  be  made,  it 
must  be  in  the  directness  by  which  the  indications  for 
treatment  are  fulfilled  at  the  precise  point  where  the 
efifect  is  demanded  without  compromising  normal  action 
or  function  of  neighboring  parts. 

The  natural  variability  of  the  spine  and  the  small  size 
of  its  muscles  as  compared  with  those  surrounding  the 
hip-joint  furnish  conditions  which  render  continuous  un- 
remitting extension  far  less  imperative.  Accordingly  it 
has  been  demonstrated  by  careful  trials  that  any  sup- 
posed necessity  for  "  night  treatment "  is  obviated  by 
daily  active  extension,  and  that  improvement  is  more 
rapid  when  the  natural  sleep  is  not  interfered  with  by  any 
form  of  restriction  or  compression. 

It  is  to  be  regretted  that  the  attention  which  the  mag- 
nitude of  the  misfortune  of  spine  disease  must  have  com- 
pelled from  physicians  in  all  ages  has  been  so  largely 
devoted  to  discussions  of  their  supposed  strumous  or 
tubercular  origin. 

In  the  quest  for  a  cause  of  the  progressive  ravages  of 
maladies  that  contain  in  their  peculiar  location  all  the 
conditions  of  perennial  disease  in  the  constant  attrition 
of  the  diseased  surfaces  or  the  cumulative  action  of  its 
producing  causes,  the  simple  fact  that  no  irritated  or 
abraded  joint  surface  can  recover  when  subjected  to  con- 
stant spasm  or  pressure  is  forgotten  in  the  wild  and  profit- 
less search  for  an  original  sin  of  scrofula  or  tuberculosis. 

Regarding  so-called  "  Pott's  disease "  and  so-called 
'*  hip  disease  "  as  identical  in  their  causes,  course,  and 
general  characteristics,  I  intend  to  supply,  for  similar 
reasons,  an  identical  treatment  purposing  to  answer  the 
universal  indication  for  elastic  extension,  appropriate  to 
any  stage,  but  especially  intended  for  convenient  and 
ready  fulfilment  of  all  requirements  at  the  outset  of  the 
disease  in  accordance  with  scientific  authority  and  sound 
pathology.  There  is,  therefore,  no  longer  any  reason 
why  every  practitioner  should  not  undertake  the  treat- 
ment of  these  cases  as  of  any  other  lesions  that  come 
under  observation  in  the  ordinary  routine  of  practice. 

There  is  abundant  reason  why  he  should  adopt  such  a 
course.  It  is  only  by  immediate,  persistent,  and  early 
attention  to  the  requirements  that  deformity  can  be  pro- 
hibited or  its  development  arrested.     Hence  the  neces- 


sity for  recognizing,  as  a  part  of  the  general  practitioner's 
duty,  a  thorough  acquaintance  with  the  early  manifesta- 
tions of  these  diseases,  and  the  instant  or  earliest  possible 
application  of  elastic  extension  by  comfortable,  efficient, 
and  unobjectionable  apparatus. 

330  Wkst  Fifty-ninth  Strsbt,  Nbw  York. 


A  CASE  OF  CYSTICERCUS  IN  THE  VITREOUS. 
By  JAMES  L.   MINOR,  M.D., 

pathologist    and  assistant    StntGBON  TO    THB    NEW  YOKK    BYB    AND  BAR    IN 
FIRMARY. 

During  the  past  summer  a  patient  consulted  me  at  the 
New  York  Eye  and  Ear  Infirmary  for  impaired  vision, 
and  I  made  the  diagnosis  of  cysticercus  in  the  vitreous. 
The  extreme  rarity  of  such  cases — not  a  single  authen- 
tic case,  so  far  as  I  am  aware,  having  been  observed  in 
America,  although  Graefe  found  eighty  cases  of  cysticer- 
cus in  the  deeper  tissues  of  the  eye,  among  eighty  thou- 
sand patients  seen  by  him  in  Germany — caused  at  first 
much  doubt  in  my  mind ;  but  the  patient  has  been  fre- 
quently and  carefully  observed  since  he  was  first  seen, 
and  I  am  now  confident  that  the  diagnosis  was  correct. 
And  I  am  strengthened  in  my  conclusion  by  the  opinions 
of  some  of  my  confreres  of  the  New  York  Ophthalmo- 
logical  Society — where  the  patient  was  shown — who  have 
seen  cases  of  cysticercus  in  the  vitreous  in  the  European 
clinics.  The  patient  has  repulsed  all  overtures  pointing 
toward  an  operation  for  the  removal  of  the  entozoon,  and 
I  simply  desire  to  place  the  case  on  record,  with  the 
hope  that  I  may,  at  some  future  time,  add  the  result  of 
the  operation  thereto. 

J.  M ,  aged  sixty,  male  ;  seen  in  July,  1884,  when 

the  following  notes  were  made  :  Ten  days  ago  suffered 
great  reduction  in  vision  in  the  right  eye,  which  has  re- 
mained almost  unchanged  since.  Vision  in  right  eye  =^^7^^, 
with  excentric  fixation,  vision  being  possessed  only  in 
the  temporal  half  of  the  visual  field.  The  ophthalmo- 
scope shows  detachment  of  the  retina  throughout  the 
temporal  half  of  the  fundus.  Far  forward  in  the  supero- 
temporal  quadrant,  just  behind  the  ciliary  body,  is  a  cyst, 
nearly  transparent,  of  ovoid  form,  which  contains  (?)  a 
cylindrical  mass,  apparently  about  one-half  of  an  inch 
long,  and  one-eighth  of  an  inch  thick,  that  terminates  in 
a  free,  somewhat  pointed  extremity.  Just  behind  the 
tip,  on  either  side,  is  a  small  black  dot — hooklets — and 
behind  these,  a  slight  constriction — the  neck — above 
which,  after  gradual  enlargement,  the  tongue-like  process 
reaches  a  point  so  far  forward  that  it  cannot  be  seen. 
Two  parallel  bands  of  delicate  whitish  tissue  can  be 
traced  from  the  neck  up  to  the  point  at  which  the  whole 
object  is  lost  to  view.  The  upper  part  of  the  cyst  is  lost 
to  view  at  the  same  point.  The  retina,  as  it  approaches 
the  cyst,  assumes  a  wavy  and 
wrinkled  outline,  and  presents  a 
mottled  appearance,  being  in- 
terspersed with  a  number  of 
small  grayish  spots  (see  figure). 
The  obliquity  of  the  eye  neces- 
sary for  a  proper  view  is  such  as  ^ 
to  make  it  difficult  to  distinguish 
between  movements  of  the  ^ 
globe  as  a  whole  and  individual 
movements  of  objects  in  its  in-  as  seen  by  the  ^/r^^/ method  of 
terior.     Yet  I  hava  satisfied  my-  examination, 

self — as  others  have  done — that  the  tongue-like  process 
does  possess  individual  movements.  I  have  observed  slight 
lengthening  and  shortening,  a  little  lateral  movement 
and  tremulousness  of  the  process.  The  position  of  the 
entozoon  is  such  as  to  make  it  impossible  to  establish 
the  exact  relation  of  parts.  The  junction  of  the  neck 
with  the  cyst-body  cannot  be  seen,  and  the  cyst  is  so 
transparent  that  it  cannot  be  positively  said  whether  the 
head  and  neck  are  contained  therein,  or  whether  they  lie 
free  in  the  vitreous,  just  in  front  of  the  cyst     I  am  in- 


704 


THE  MEDICAL  RECORD. 


[December  27,  1884. 


dined  to  think  that  the  latter  is  the  case ;  for  with  the 
inverted  image  a  marked  parallax  can  be  obtained,  which 
not  only  shows  considerable  depth  to  the  cyst-cavity, 
but  that  the  head  and  neck  lie  well  forward,  in  the  ante- 
rior part  of  the  cyst,  or  entirely  in  front  of  the  cyst- wall. 

3x  Park  Avbnub. 


A  NEW  METHOD  OF  MAKING  INTRAVESI- 
CAL INJECTIONS,  AND  ITS  VALUE  IN  THE 
TREATMENT  OF  CYSTITIS. 

By  C.  W.  ROBBINS,  M.D., 

MARINBTTB,  WIS.] 

Some  three  years  ago,  while  practising  in  Milwaukee,  I 
was  called  upon  to  treat  a  case  of  gonorrhoeal  cystitis  in 
a  young  man.  The  case  was  aggravated  and  chronic ;  it 
had  already  existed  seven  weeks,  and  persisted  for  ten 
days  longer  in  my  hands  without  improvement  with  the 
usual  remedies  and  rectal  suppositories.  The  urine 
showed,  on  standing,  a  large  amount  of  pus  and  mucus. 
In  bulk  the  sediment  was  about  one-fourth  of  the  whole 
amount  of  urine  in  bottle  (a  four-ounce  bottle  full).  Hav- 
ing no  instrument  for  injecting  the  bladder,  I  decided  to 
try  a  Davidson  syringe  and  inject  directly  into  the  blad- 
der per  urethra.  I  first  injected  warm  salt-water  into  my 
own  bladder  to  test  the  feasibility  of  the  plan.  The  fluid 
passed  in  nicely,  halting  only  for  two  minutes  at  the 
sphincter.  I  then,  the  next  time  my  patient  came,  in- 
jected his  bladder  with  a  solution  (100°  F.)  of  potassium 
chlorate  and  permanganic  acid,  injecting  ten  ounces  of 
the  fluid,  without  causing  my  patient  the  slightest  pain  or 
discomfort.  The  patient  held  the  fluid  about  one  minute, 
and  the  injection  was  repeated.  In  all,  the  bladder  was 
thoroughly  washed  out  four  times  at  this  sitting.  The 
same  treatment  was  practised  the  next  day,  and  again  on 
the  following  day,  with  the  result  of  curing  my  patient 
entirely  in  the  three  days.  At  least  all  symptoms  dis- 
appeared, and  my  patient  had  no  relapse.  About  that 
time  1  removed  from  Milwaukee  to  the  country  and  have 
only  had  two  similar  cases  to  treat  since,  in  both  of  which 
the  resulting  cure  was  rapid  and  permanent;  one  case 
being  cured  in  three  sittings  and  the  other  m  five  sittings. 
The  injection  used  is  the  one  I  have  always  used  in 
gonorrhoea. 

As  I  use  it  |it  is  entirely  unirritating.  I  use  from  one 
to  three  drachms  of  the  permanganic  acid  to  a  half-satu- 
rated solution  of  potassium  chlorate,  |  xvj.  The  perman- 
ganic acid  I  made  myself  after  the  followingjormula  : 

9  •  Potass,  permanganate grs.  ix. 

Aqua  destil |  j. 

Solve  et  adde 

Sulphuric  acid,  C.P • . . . .  TRiij. 

This  is  not  strictly  a  permanganic  acid  solution,  but  it 
will  do. 

In  this  brief  note  I  have  not  gone  into  details  because 
I  am  not  at  all  sure  that  the  title  at  the  head  of  my  paper 
will  hold  good  upon  investigation. 

If  this  method  of  treating  cystitis  is  new  and  original, 
I  ask  of  you  to  give  this  paper  space  in  your  columns, 
hoping  that  some  of  you  New  York  surgeons  will  test  the 
treatment  thoroughly. 


Micrococci  of  Pneumonia  associated  with  Scarlet 
Fever  and  Diphtheria. — Dr.  Lumbrosa  concludes,  from 
the  examination  of  four  cases,  and  culture  experiments, 
that  the  micrococcus  found  in  broncho-pneumonia  occur- 
ring in  scarlet  fever,  diphtheria,  and  croup,  although  iden- 
tical in  form  with  that  of  true  pneumonia,  is  not  biologically 
the  same.  He  was  never  able  to  reproduce  the  disease 
from  the  pure  cultures.  He  believes  that  in  infectious 
diseases  the  pneiunonia  coccus  has  altered  properties. — 
Le  Progrls  MhiiccUe^  October  18,  1884. 


THE  IMMUNITY  OF  THE  NEGRO  FROMTRA- 
CHOMA, 

By  BENJAMIN  L  BALDWIN,  M.D., 

BX-HOUSB  SUKGBON  OP  THB    MANHATTAM    SYB  AMD  BAIt    HOSPITAL,  NKir  VOK' 
SUXGBON  TO  THB  MOMTCOMBKY  BVB,  BAR,  AMD  THBOAT  nfratUAIV.        ' 

In  the  last  issue   of  the  Archives  of  Ophthalmology 
there  was  a  good  paper  by  Dr.  S.  M.  Burnett  on  "The 
Frequency  of  Eye  Diseases  in  the  White  and  Colored 
Races  of  the  United  States."     The  susceptibility  and 
insusceptibility  of  the  negro  race  to  certain  diseases  is 
well  known  in  the  South.     I  will  not  attempt  to  give 
a  reason  for  this,  nor  could  I  do  so  in  many  instance! 
The  principal  point  which  Dr.  Burnett  makes  is  the  im- 
munity which  the  negro  enjoys  from  trachoma,  and  my 
object  is  to  add  my  experience  to  his  on  that  subject 
The  city  of  Montgomery  is  the  centre  of  the  great  coUon 
belt  of  Alabama,  and  the  country  which  surrounds  the 
city  is  low  and  flat,  and  the  soil  very  rich.     This  peculiar 
kind  of  soil  in  the  South  is  cultivated  almost  entirely  by 
the  negro,  so  that  we  have  around  us  an  immense  negro 
population.     During  the  past  eighteen   months  I  have 
treated  four  hundred  and  eighty  cases  of  eye  diseases 
among  the  negroes,  and  I  have  yet  to  find  a  genuine  case 
of  tenement-house  trachoma  among  them.     I  have  kept 
an  accurate  history  of  all  my  cases,  both  in  private  and 
dispensary  practice,  and  I  believe  that  my  data  are  of 
some  help  to  Dr.  Burnett  in  establishing  an  interesting 
clinical  fact.     I  have  seen  many  cases  of  papular  con- 
junctivitis due  to  the  lack  of  proper  treatment  of  ordi- 
nary ''  sore  eyes,"  but  this  is  easily  accounted  for,  as  the 
race  is  careless  about  such  mild  troubles,  and  medical 
attention  is  not  easily  obtained  in  remote  rural  districts 
in  the  South.     I  do  not  care  to  discuss  the  nice  distinc- 
tions which  some  analytical  writers  impose  upon  us,  but 
that  there  is  a  great  difference,  clinically,  between  tene- 
ment-house trachoma  and  papular  or  granular  conjuncti- 
vitis, due  to  a  mild,  protracted  inflammation  of  the  con- 
junctiva, I  think,  will  not  be  denied.     Dr.  Burnett  says: 
*'  If  it   should  turn  out  that  the  negro  does  not  suffer 
from  trachoma,  even  when  the  surrounding  conditions 
are  such  as  usually  develop  it  in  other  races,  we  have  a 
new  element  th^it  must  be  taken  into  account  in  studying 
that  most  important  eye  affecrion."      Ah  I  this  an  impor- 
tant point  to  look  into.     Has  Dr.  Burnett  ever  found  the 
negro  living  in  large  numbers  under  the  same  conditions 
which  develop  trachoma  among  the  poor  white  element 
of  our  large  cities  ?     I  think  here  is  the  place  we  may 
go  astray  in  our  statistics,  if  we  do  not  reason  carefully. 
To  my  mind,  the  lack  of  trachoma  among  the  large  num- 
ber of  negroes  treated  by  me  is  explained  by  the  fact 
that  they  have  been  among  a  class  who  have  had  a  boun- 
tiful supply  of  fresh  air,  abundant  sunlight,  and  plenty  of 
exercise.     Given  a  constitution  free  from  any  taint,  widi 
these  elements,  together  with  sufficient  and  proper  diet,  1 
challenge   the  invasion   of  trachoma,  come  what  may. 
My  opinion  is,  and  will  be  till  some  good  argument  con- 
vinces me  that  I  am  wrong,  that  in  all  trachoma  there  is 
to  be  found,  as  a  fundamental  cause,  a  dyscrasia.    It  is 
true  that  the  negroes  of  the  South  are  poor,  and  they 
are  often  found  greatly  crowded  in  their  cabins  ;  yet  these 
cabins  are  so  constructed  that  there  is  never  a  lack  of 
ventilation.     I  do  not  contend  that  trachoma  is  never 
found  in  the  negro,  for  I  saw  one  case  during  my  term 
of  service  at  the  Manhattan  Eye  and  Ear  Hospital,  bat 
I  do  say  that  they  enjoy  a  wonderful  immunity  from  it, 
and  I  will  reiterate  that  I  have  yet  to  find  a  true  case  of 
trachoma  among  the  negroes  in* my  locality  in  the  South. 

MONTGOMBSY,  AlA. 

Hydrocele  and  Cysto-sarcoma  Cured  by  Opera- 
tion.— Dr.  J.  M.  Adams,  of  Spencer,  Wis.,  reports  a  case 
of  a  patient,  set.  38,  suffering  from  an  enormous  hydrocele, 
the  scrotum  reaching  below  the  knee.  Twelve  quarts  of 
fluid  were  removed  from  the  sac.  Incisions  were  then 
made,  and  a  tumor  attached  to  testes  and  tunica,  weighing 
2^  lbs.,  was  removed-  The  patient  made  a  good  recovciy. 


December  27,  i884,] 


THE   MEDICAL  RECORD. 


705 


TREATMENT     OF    CHRONIC    HYDROCEPHA- 
LUS BY  TAPPING— A  SUCCESSFUL  CASE. 
By  J,  G.  PALMER,  M.D., 

OAKBOWBRYy  ALA. 

I  WISH  to  report  a  case  of  successful  treatment  of  con- 
genital hydrocephalus.  The  patient  was  a  negro  baby, 
seven  months  old.  I  was  called  to  see  the  child  in  July 
last.  I  diagnosticated  the  case  as  one  of  congenital 
hydrocephalus,  and  told  the  parents  that  the  only  hope 
for  cure  was  in  tapping.  To  this  they  would  not  consent. 
The  accumulation  continued  until  the  head  reached 
the  enormous  size  of  twenty-six  inches  in  circumfer- 
ence— the  bones  of  the  head  having  become  very  thin 
by  reason  of  the  pressure  from  within.  There  was  a  space 
of  two  inches  between  the  bones.  The  eyes  were  turned 
up  under  the  upper  lids  from  pressure  upon  the  brain. 

In  consultation  with  Drs.  Garison  and  Spratling  the  im- 
portance of  tapping  was  urged  and  the  parents  consented. 
A  small  hydrocele  trocar  was  inserted  at  the  posterior  por- 
tion of  the  anterior  fontanelle,  the  head  having  first  been 
shaved  at  the  place  of  insertion  of  the  trocar. 

The  fluid  flowed  freely.  About  eight  ounces  were  drawn 
off,  the  trocar  withdrawn,  and  a  piece  of  absorbent  cotton 
placed  over  the  place  of  puncture,  and  held  in  place  by  a 
piece  of  adhesive  plaster.  The  bones  of  the  head  were 
pressed  into  position,  and  held  in  place  by  a  tightly  fitting 
bandage. 

Next  day  bandage,  plaster,  and  cotton  were  removed, 
and  more  fluid  was  allowed  to  drain  off,  though  much 
had  done  so  during  the  night  by  the  plaster's  coming  oflf 
and  the  cotton  being  moved  out  of  position.  The  fluid 
was  allowed  to  drain  off  at  intervals  until  all  was  removed. 

The  child  was  then  put  upon  iodide  of  potash,  which 
was  kept  up  for  several  weeks.  The  eyes  soon  regained 
their  normal  position.  The  child  nursed  well  and  fat- 
tened rapidly.  There  were  some  febrile  symptoms  for 
several  days  after  the  operation,  but  they  soon  subsided. 

The  head  is  yet  big  from  the  large  size  of  the  bones, 
they  being  very  thin.  The  bones  seem  to  be  rapidly 
uniting,  and  the  child  is  still  fattening  and  growing. 


SUBSTITUTES   FOR  SAYRES'   PLASTER-OF- 
PARIS  JACKETS. 

By  J.  W.  KALES,  M.D., 

FRANKUNVILLB,  N.   Y. 

In  a  recent  number  of  The  Medical  Record  Dr.  S.  W. 
Smith  brings  forward  a  substitute  for  plaster-of-Paris  for 
the-  construction  of  spinal  supports,  and  urges  some  ob- 
jections to  the  use  of  Say  res*  admirable  and  original 
apparatus.  The  writer  having  had  considerable  experi- 
ence, and  having  used  many  kinds  of  material  in  the  con- 
struction of  spinal  supports,  fails  to  comprehend  wherein 
lies  the  superiority  of  Dr.  Smith's  instrument.  How 
it  could  have  warded  off  the  sad  termination  of  Case  I., 
or  have  produced  less  constriction  of  the  chest-walls  in 
Case  II.,  as  quoted  by  the  doctor,  is  not  quite  clear,  pro- 
vided the  surgeon  had  properly  applied  the  plaster-of 
Paris  splint. 

The  writer  has  in  his  possession  a  spinal  support  which 
was  constructed  four  years  ago,  and  exhibited  at  the  July 
meeting  of  the  Cayuga  County  Medical  Society  in  1880. 
This  support  is  constructed  of  narrow  strips  of  tin.  It 
was  built  over  a  cast  of  plaster-of-Paris  procured  in  the 
usual  manner.  Part  of  the  strips  of  tin  were  placed 
vertically  upon  the  cast,  the  remainder  of  them  horizon- 
tally, and  were  soldered  at  the  points  of  intersection.  A 
wire  was  run  around  the  edges  of  the  splint,  thus  forming 
an  almost  exact  counterpart  of  Dr.  Smith's  instrument. 

This  support  is  easily  and  cheaply  constructed  by  any 
good  tinsmith ;  is  light,  elastic,  appears  well  on  paper, 
looks  well  when  exhibited  before  a  medical  society,  and 
when  lined  with  chamois  and  covered  with  some  fine  mate- 
rial, as  silk  and  lace,  up  in  front,  pleases  the  eye  of  pa- 
tient and  friends.     But  having  constructed  several  they 


have  been  abandoned.  They  are  metal.  The  slightest 
imperfection  soon  acts  like  a  nail  that  projects  through 
the  sole  of  a  shoe,  and  it  is  very  difficult  to  avoid  such 
imperfections.  The  perspiration  attacks  the  metal,  and 
the  oxide  of  iron  attacks  the  clothing  ;  the  patient  can  re- 
move the  splint,  and  soon  it  is  relegated  to  the  garret. 
Such  has  been  my  experience  with  metal  spinal  supports. 

If  we  are  to  use  anything  except  plaster-of-Paris,  we 
would  suggest  leather.  Leather  splints  are  easily  con- 
structed by  first  thoroughly  soaking  the  leather  in  water 
and  then  stretching  it  over  the  plaster  cast  When  dry, 
remove  it  from  the  cast  and  apply  it  to  the  patient. 
Any  imperfection  can  then  be  easily  corrected.  Having 
secured  2^ perfect  "fit,"  finish  the  support  by  perforating 
it  to  any  required  extent,  line  and  cover  it  with  any  desir- 
able material,  lace  it  in  front,  attach  jury  mast,  head- 
rest, or  other  desirable  attachment.  In  the  writer's 
hands  leather  has  proved  very  satisfactory.  When  the 
disease  is  located  in  the  lumbar  region  the  plaster-of-Paris 
splints  do  not  work  as  satisfactorily  as  when  the  dorsal 
region  is  affected. 

In  one  case  where  the  lumbar  region  was  seriously 
affected,  and  Sayres*  jacket,  after  many  trials,  had  proved 
inefficient,  and  where  a  splint  constructed  by  one  of  New 
York's  best  instrument-makers  completely  failed  to  give 
adequate  support,  the  writer  applied  a  leather  jacket. 
By  extending  the  lower  edge  of  the  jacket  over  the 
crests  of  the  ilia  and  down  quite  to  the  greater  tro- 
chanters, the  body  of  the  pelvis  formed  a  fixed  point  of 
support.  This  jacket  has  been  worn  for  more  than  a 
year.  The  patient  has  steadily  improved,  and  her  friends 
confidently  expect  complete  recovery. 

OCTOBBR  32,  1884. 

Professor  Frerichs  on  Diabetes. — The  compre- 
hensive  work  of  Frerichs  on  diabetes  forms  the  most 
valuable  recent  contribution  to  the  literature  of  the  sub- 
ject. A  summary  of  the  author's  views  is  given  in  the 
Centralblatt  fur  die  Medizinischen  Wissenschaften^  No. 
41,  1884.  The  author  distinguishes  three  prinicpal  vari- 
eties of  glycosuria,  i.  Glycosuria  after  poisons,  which 
constantly  occurs  after  poisoning  by  curare,  carbonic 
oxide,  amyl-nitrite,  ortho-nitro-phenyl-proprionic  acid,  and 
methyl-delphinin.  It  occasionally  occiu"s  after  large  quan- 
tities of  morphia,  chloral-hydrate,  hydrocyanic  acid,  sul- 
phuric acid,  mercury,  and  alcohol.  Glycosuria  after  in- 
fectious diseases  is  allied  to  the  above  ;  e.g.^  cholera, 
anthrax,  diphtheria,  typhoid  fever,  scarlatina,  and  malaria. 
In  the  last-named  disease  it  was  only  found  once  in  several 
hundred  cases.  The  appearance  of  a  copper-reducing 
substance  in  the  urine,  observed  by  different  authors  after 
the  introduction  of  various  substances  into  the  body, 
does  not  rest  on  the  presence  of  sugar. 

2.  Glycosuria  from  digestive  derangements.  While,  as  a 
rule,  in  healthy  persons  the  ingestion  of  large  quantities 
of  sugar  does  not  cause  glycosuria,  exceptional  cases  oc- 
cur, in  which  even  small  quantities  have  this  result.  Apart 
from  this,  glycosuria  is  found  occasionally  in  connection 
with  gastric  catarrh,  especially  in  those  who  inherit  a  gouty 
disposition.  It  chiefly  occurs  during  the  intervals  of 
gouty  attacks.  Experiments  on  the  introduction  of  sugar 
in  cases  of  phosphorus-poisoning,  cirrhosis  of  the  liver, 
and  portal  obstruction,  gave  only  negative  results  as  to 
the  presence  of  sugar  in  the  urine. 

3.  Glycosuria  from  nervous  derangement  This  in- 
cludes glycosuria  after  psychic  excitation,  neuralgia,  cere- 
bral disturbance,  injuries  of  the  head  and  spinal  column, 
and,  finally,  cerebral  hemorrhage  and  cerebro-spinal  men- 
ingitis. 

Diabetes  mellitus  is  distinguished  from  glycosuria  by 
the  appearance  of  extensive  derangements  of  the  tissue- 
changes  generally,  which  lead  to  general  deteriora- 
tion, to  many  local  diseases,  and  usually  to  death.     In 


7o6 


THE   MEDICAL  RECORD. 


[December  27,  ii%^ 


speaking  of  the  results  of  diabetes,  twelve  cases  of  cure 
are  given.  It  often  passes  into  some  other  grave  disease 
— nephritis,  diabetes  insipidus,  arterial  sclerosis,  and 
their  consequences.  But  death  is  far  the  most  frequent 
result  j  and,  of  250  fatal  cases  of  the  author's,  18  died 
from  exhaustion,  34  from  phthisis,  7  from  pneumonia  (4 
of  these  with  gangrene  of  the  lungs),  8  from  nephritis,  7 
from  carbuncle,  and  9  from  complications  (6  of  these 
from  cancer).  In  all  the  other  cases  symptoms  of  cere- 
bral paralysis  appeared,  in  10  from  hemorrhage,  in  2 
from  softening,  in  3  from  cerebro-spinal  meningitis,  and 
in  the  rest  from  coma  without  local  alterations  within  the 
skull.  Fifty-five  cases  are  reported,  together  with  their 
necropsies.  Passing  over  the  causes,  immediate  and  pre- 
disposing, of  diabetes,  we  come  to  the  treatment,  which 
is  not  so  powerless  as  is  often  assumed,  for  the  author  has 
had  cases  under  treatment  for  ten  years  up  to  eighteen 
years,  and  one  case  for  twenty  years.  A  proper  mental 
and  bodily  diet  is  of  the  greatest  importance,  and  mus- 
cular exercise  carefully  conducted  is  most  beneficial. 
Milk  was  found  unfavorable,  especially  Donkin's  treat- 
ment by  skimmed  milk.  Many  alkaline  waters  were 
found  very  useful  (Carlsbad,  Neuenahr,  Vichy),  when 
taken  at  these  places.  Among  narcotics,  opium  is  im- 
portant, as  it  often  lessens  thirst,  urine,  and  sugar,  while 
the  body-weight  increases.  As  to  the  experience,  usually 
negative,  of  many  so-called  specifics,  lactic  acid  had  no 
result,  and  glycerine  was  harmful.  Salicylic  acid,  salicy- 
late of  soda,  and  iodoform  deserve  further  trial.  All 
weakening  influences  and  cutaneous  irritants  are  to  be 
avoided. 

Infectious  Osteomyelitis, — Dr.  Rodet  has  found 
that  when  the  micrococci  of  the  pus  in  cases  of  osteo- 
myelitis are  injected  into  the  venous  system  of  rabbits, 
and  therefore  free  to  choose  their  seat,  they  show  a 
marked  preference  for  the  bones,  and  more  especially  for 
those  parts  which  are  in  process  of  active  growth,  where 
they  set  up  a  severe  suppurative  or  necrotic  form  of 
osteitis  analogous  to  osteomyelitis  in  man. 

Sleep,  Trance,  and  Death. — Occasionally  we  meet 
with  instances  in  which  death  is  simulated  by  some  deep 
degree  of  stupor.  The  case  of  a  laborer,  living  at  Bridge- 
water,  which  was  lately  recorded,  appears  to  have  been 
one  of  this  kind.  The  trance-like  state  developed  quite 
suddenly,  and  was  mistaken  by  the  relatives  for  death. 
Some  slight  degree  of  warmth  in  the  apparent  corpse  in- 
duced the  clergyman  in  attendance  to  refuse  burial  in 
spite  of  the  decided  wish  of  the  relatives  that  it  should 
take  place.  After  eight  days,  the  signs  of  animation  were 
re-established,  and  the  subject  of  this  singular  experience 
slowly  recovered.  In  all  such  cases,  there  is  an  element 
of  mystery  ;  and  one  cannot  always  decide  how  much  of 
this  is  due  to  physiological  or  pathological  conditions,  or 
to  some  external  agency.  The  British  Medical  Journal, 
in  commenting  upon  the  above  case  is  led  to  make  the 
following  remarks :  "  The  relationship  between  sleep,  *the 
cousin  of  death,'  and  death  itself,  is  probably  real  as  well 
as  apparent.  The  distance  which  separates  them  is 
great,  but  there  are  intermediate  connections,  grades  of 
dissolution  as  of  development.  Among  these  the  similar 
states  of  trance  and  hibernation  are  worthy  of  special 
notice.  For  sleep  and  for  trance  one  cause,  the  exhaust- 
ion chiefly  of  nervous  matter,  but  more  or  less  of  every 
organ  and  tissue,  is  assignable.  The  hysterical  stupor  is 
the  sleep  of  nerve-centres,  worn  out  with  the  assault  and 
conflict  of  stormy  reflex  action.  Healthy  sleep  is  the  rest 
of  physical  elements  wearied  with  the  same  strain  applied 
more  gradually.  Cases  have  been  recorded  in  which 
somnolence,  continuing  for  days  without  cessation,  has 
resembled  tratice  in  its  duration,  while  preserving  all  the 
ordinary  features  of  natural  sleep.  Various  facts  support 
us  in  associating  the  hibernation  of  animals  with  the 
same  train  of  organic  or  functional  changes  as  the  other 
unconscious  states  which  we  have  been  considering.  It 
comes  hke  a  habit ;  it  has,  one  may  say,  annual  return ; 


its  apparent  cause  is  the  oppression  of  external  cold,  and 
the  animals  it  affects  are  mostly  those  which,  fi:om  their 
bodily  structure  or  habits,  are  subject  to  great  periodic 
variations  of  temperature.  Vital  tissue  is  exhausted,  and 
function  is  in  part  suspended,  probably  because  the 
numbness  of  cold  has  taken  hold  upon  the  radicles  of  the 
outer  circulation,  and  of  that  of  the  brain-surface  which 
is  connected  with  it  by  numerous  anastomoses.  In  such 
a  case  anaemia  would  seem  to  be  the  cause  of  the  winter 
sleep,  as  there  is  evidence  to  show  that  it  is  also  the 
cause  of  that  temporary  starvation  of  brain  which  lulls 
without  arresting  its  action,  in  the  natural  repose  of  each 
night.  We  may  even  regard  the  lethargy,  ended  by 
death,  into  which  man  falls  when  exposed  to  great  cold, 
as  a  short  and  mortal  hibernation.  The  same  influence 
acts  upon  him  as  upon  the  bear  or  fish,  but  the  power  of 
its  shock  is  greater  on  his  finer  and  less  accustomed 
senses  than  on  their  comparatively  coarse  organization. 
So,  likewise,  in  other  regions  and  forms  of  life,  in  the  weari- 
ness, paralysis,  atrophy,  and  gangrene  of  limbs,  in  the 
leafless  hibernation  of  trees,  and  in  their  decay,  begin- 
ning in  the  terminal  twigs,  the  same  teaching  is  evident, 
that  vascular  nutrition,  in  its  periodic  variations,  is  the 
parent  of  activity,  and  of  rest,  as  its  absence  is  of  death." 

Adenoma  of  the  Liver  in  a  Child  Twenty  Months 
Old. — A  remarkable  instance  of  this  rare  disease  is  found 
in  the  yearly  report  of  the  St.  Joseph  Children's  Hospital 
in  Vienna.  A  female  child  had  suffered  for  three  months 
with  loss  of  appetite,  emaciation,  and  swelling  of  the  ah- 
dompn.  The  right  side  of  the  abdomen  was  occupied  by 
a  tumor  reaching  from  the  sixth  rib  to  the  iliac  fossa,  and 
on  a  line  with  the  umbilicus  from  the  linea  alba  to  the 
vertebral  column.  Palpation  showed  elevations  over  the 
surface  of  the  liver  from  the  size  of  a  horse-chestnut  to 
that  of  a  child's  fist  They  appeared  soft  when  pressed 
against  the  resilient  liver.  There  was  also  enlargement 
of  the  spleen,  and  the  urine  showed  albumen.  At  the 
autopsy  the  liver  was  found  to  weigh  over  three  pounds. 
Its  surface  was  covered  with  knobby  tumors  of  various 
sizes.  Section  showed  the  liver  substance  to  be  entirely 
replaced,  with  exception  of  its  periphery,  by  a  soft  yel- 
low mass  sprinkled  with  numerous  hemorrhagic  points. 
It  was  separated  from  the  resistant  liver  tissue  by  a  thin 
capsule.  Connective  tissue  septa  ran  through  the  mass, 
indicating  that  it  had  been  formed  from  a  number  of  con- 
fluent tumors.  There  were,  besides  this  large  mass,  tu- 
mors from  the  size  of  a  pea  to  that  of  a  walnut  scattered 
over  the  periphery.  Some  were  so  soft  that  they  almost 
fluctuated.  Careful  microscopic  examination  showed  the 
growth  to  be  an  atypical  adenoma. —  Wiener  Medisin- 
ische  Wochenschrift^  No.  43,  1884. 

Sudden  Death  in  Labor  and  Childbed. — In  the 
course  of  some  remarks  on  the  above  subject.  Dr.  Lusk 
{Journal  of  the  American  Medical  Association,  October 
18,  1884)  observes  that  modem  pathological  investigation 
refers  the  phenomena  of  shock  to  a  reflex  paralysis  of 
the  vaso-motor,  and  especially  of  the  splanchnic  nerves, 
whereby  the  great  mass  of  the  blood  is  withdrawn  from 
the  surface,  and  collects  in  the  lar^e  trunks  of  the  coeliac, 
the  mesenteric,  and  the  renal  veins.  Hence  the  skin 
becomes  cold  and  is  devoid  of  color,  save  at  the  points 
where  a  bluish  hue  is  imparted  by  the  stagnant  blood 
still  lingering  in  the  veins ;  the  muscles  deprived  of  blood 
become  enfeebled ;  and  the  empty  vessels  of  the  brain 
explain  the  sluggish  intelligence,  the  nausea,  the  vomit- 
ing and  the  indifference  of  the  patient ;  finally,  during 
the  diastole,  the  heart,  pale  and  contracted,  receives  but 
little  blood,  and  the  radial  pulse  fades  to  nothingness, 
because  a  corresponding  small  amount  of  fluid  is  pro- 
pelled during  the  systole  into  the  arterial  vessels.  From 
works  on  military  surgery  we  learn  that  it  is  in  the  de- 
feated army  among  homesick  soldiers,  at  the  close  of  a 
wearisome  war  after  great  exertions  and  deprivations, 
that  shock  is  developed  in  its  severest  forms ;  that  the 
finer  the  organization,  the  more  readily  the  manifesta- 


December  27,  1884.] 


THE   MEDICAL  RECORD. 


707 


tions  occur ;  that  they  are  promoted  by  sudden  losses  of 
blood,  and  are  in  a  special  degree  evoked  by  abdominal 
injuries.     It  certainly  would  be  singular  if  similar  condi- 
tions in  childbed  were  not  followed  by  corresponding  re- 
sults.   After  prolonged  labor,  the  woman  has  her  nervous 
system  depressed  by  pain,  starvation,  and  deprivation  of 
sleep.    The  sudden  emptying  of  the  uterus  is  followed  by 
a  recession  of  blood  to  the  venous  trunks  of  the  abdomen. 
Hemorrhage  subsequent  to   parturition  is  followed  by 
syncope,  and   the  wonder  is,  not  that  the  circulation 
should  occasionally  show  the  evidences  of  marked  and 
even  fatal  disturbance,  but  that  the  nervous  system,  at- 
tacked from  so  many  directions,  should,  as  a  rule,  triumph 
over  the  adverse  forces.     In  the  old  days  of  torture, 
shock  often  mercifully  put  an  end  to  the  victim's  anguish. 
Women  in  childbirth  are  at  times  subjected  to  pam  ex- 
ceeding that  of  the  rack  and  the  thumb-screw.     Now  it 
is  not  sound  pathology  to  ignore  these  facts,  and  to  ban- 
ish as  unworthy  of  consideration  a  well-established  path- 
ological condition,  simply  because  in  the  days  of  igno- 
rance the  terms  exhaustion  and'shock  were  indiscriminately 
employed  to  explain  a  multitude  of  cases,  which,  with  our 
present  enlightenment,  we  know  are  due  to  the  entrance 
of  air  into  the  circulation  and  to  pulmonary  embolism. 
As  the  nervous  organization  of  women  loses  in  powers  of 
resistance  as  the  penalty  of  a  higher  civilization  and  of 
artificial  refinement,  it  becomes  imperatively  necessary 
for  the  physician  to  guard  her  from  the  dangers  of  exces- 
sive and  too  prolonged  suffering.     Especially  I  would 
raise  my  voice  in  warning  against  the  current  opinion 
that  the  length  of  the  first  stage  of  labor  before  the  rupt- 
ure   of   the  membranes  is  a  matter  of  indifference,  a 
teaching  which   I   believe   has  cost  the  lives  of  many 
women ;  in  a  few,  death  resulting  from  shock  ;  in  more, 
the  exhausted  condition  in  which  the  woman  is  left  after 
childbirth  rendering  her  an  easy  prey  to  the  perils  of  the 
puerperal  state.  J 

Lipoma  of  the  Arachnoid. — Dr.  Braubach  records  a 
case  of  lipoma  of  the^arachnoid  of  the  cervical  cord,  ex- 
tending to  the  point  of  exit  of  the  fourth  and  fifth  dorsal 
nerves.  The  cord  was  completely  compressed  and  dis- 
placed to  the  left  side.  Below  the  region  of  compression 
there  was  descending  degeneration  of  the  ]iyramidal 
columns.  lipoma  is  very  rare  in  this  situation.  Very 
few  such  cases  have  been  recorded  :  one  by  Obr6,  one 
by  Athol  Johnson,  one  by  Virchow,  and  a  case  of  myo- 
lipoma by  Gowers.  The  paraplegia  of  the  lower  limbs, 
their  anaesthesia,  the  bladder  weakness,  the  extreme  con- 
traction of  both  lower  extremities,  the  increase  of  their 
tendon  reflexes,  need  no  comment.  They  depend  partly 
on  the  compression  of  the  cervico-dorsal  cord,  partly  on 
the  descending  secondary  degeneration  of  the  lateral 
pyramidal  tracts.  Of  greater  interest  is  :  i.  The  fact 
that,  in  spite  of  the  extreme  compression  and  degenera- 
tion of  the  affected  part  of  the  cervico-dorsal  cord,  the 
conduction  through  it,  at  any  rate  of  intense  impressions 
of  pain,  was  still  retained.  2.  The  fact  that,  in  spite  of 
the  great  degeneration  of  the  compressed  parts,  the  roots 
on  the  right  side  that  came  off  from  these  affected  regions 
showed  only  very  slight  degeneration,  the  roots  on  the 
left  side  none.  3.  The  fact  that  the  left  upper  extremity 
could  be  moved  as  in  health,  without  any  paralysis  or 
contraction  ;  while  the  right  arm  was  paralyzed  and  ex- 
tremely contracted.  The  latter  symptom  was,  doubtless, 
due  to  the  great  amount  of  stretching  of  the  right  spinal 
roots,  in  consequence  of  the  displacement  of  the  cord  to 
the  left ;  and  a  permanent  state  of  irritation  was  present 
throughout,  which  gave  occasion  to  conic  contraction  of 
the  right  upper  extremity, — Archiv  fur  Psychiairie\und 
I^ervenkrankheiten}^ 

Bony  Tumor  of  Brain. — ^The  formation  of  true  bony 
growths  in  the  substance  of  the  brain  is  believed  to  be  of 
rare  occurrence.  It  is  possible  that  the  apparent  rarity 
is  due  to  the  infrequency  of  post-mortem  examinations  of 
the  cranial  cavities  of  senile  individuals.     M.  Witkowski 


has  placed  on  record  some  of  the  particulars  of  an  ex- 
ample of  osseous  tumor  of  the  brain.  The  morbid 
growth  was  of  the  size  of  a  walnut  and  occurred  in  the 
left  hemisphere  at  its  occipital  part ;  it  was  quite  inde- 
pendent of  the  pia  mater  or  ependyma,  being  surrounded 
on  all  sides  by  brain  matter.  Its  shape  was  like  that  of 
two  pyramids  set  together  at  their  bases ;  its  surface  was 
studded  with  a  number  of  spicules,  points,  and  folds,  the 
last  of  which  had  a  certain  resemblance  to  the  convolu- 
tions of  the  brain.  The  tumor  was  encased  in  a  fibrous 
capsule,  and  presented  many  excavations  filled  with 
brownish  or  yellowish  soft  material,  which  was  discovered 
on  microscopical  examination  to  be  of  the  same  structure 
as  the  marrow  of  hope.  The  fibrous  capsule  or  perios- 
teum of  the  tumor  was  composed  of  a  dense  connective 
tissue,  calcified  in  parts.  After  the  tumor  had  been  de- 
calcified by  treatment  with  chromic  and  nitric  acids,  a 
hyaline  ground  substance  was  brought  into  existence,  and 
lamellae  with  bone  corpuscles  and  Haversian  canals  were 
to  be  seen.  The  tumor  was  connected  with  the  ner- 
vous substance  by  means  of  a  delicate  connective  tissue 
strewed  with  amyloid  corpuscles.  There  were  no  other 
osseous  formations  in  any  part  of  the  central  nervous 
system.  The  brain  on  the  same  side  as  the  tumor  was 
certainly  more  consistent  than  the  right  hemisphere,  and 
the  microscope  exhibited  an  increase  in  the  amount  of 
connective  tissue  and  stellate  cells.  The  cerebral  arte- 
ries were  extensively  thickened,  and  many  small  foci  of 
the  brain  were  in  a  state  of  softening.  Some  degree  of 
internal  and  external  hydrocephalus  was  found,  and  the 
ependyma  was  thickened.  The  brain  was  that  of  a  man, 
aged  seventy-nine  years,  who  had  never  shown  any  S3mtip- 
toms  of  brain  mischief  during  life.  No  accident  could  be 
assigned  as  the  cause  of  the  formation,  which  does  not 
appear  to  have  been  an  ordinary  psammoma. — London 
Lancet, 

Fatal  Puerperal  Infection  in  the  Male, — Dr. 
Gandor  reports  this  case  in  the  Revue  de  M'edecine^  No.  9, 
1884  :  A  healthy  man  waited  on  his  wife  after  her  con- 
finement. The  woman  died  of  puerperal  septicaemia ;  the 
man  developed  a  lymphangitis,  preceded  by  chills,  simul- 
taneously, in  one  arm  and  leg.  Sqon  all  the  symptoms 
of  septicaemia  appeared,  and  the  patient  rapidly  sank, 
but  rallied  at  length  and  made  a  tedious  recovery.  No 
wound  or  scratch  of  any  kind  had  existed  on  his  hand  or 
foot  to  account  for  the  origin  of  the  lymphangitis.  The 
author  concluded,  therefore,  that  the  case  was  one  of 
puerperal  infection  in  the  male.  But  he  fails  to  explain 
in  what  manner  the  poison  entered  the  system. 

The  Rose-colored  Eruption  not  Characteristic 
OF  Typhoid  Fever. — Dr.  Juhel  R6noy  relates  in  the 
Archives  Centrales  de  M^decine  for  October,  1884,  two 
cases  in  which  the  typical  rose-colored  eruption  was  pres- 
ent, but  in  which  there  was  no  typhoid  fever.  In  one 
case  there  was  diarrhoea  and  fever,  but  the  temperature 
curve  was  not  that  of  typhoid,  and  at  the  autopsy  no 
typhoid  lesions  were  discoverable.  The  author  con- 
cludes, therefore,  that  the  presence  of  the  rose-colored 
lenticular  spots  is  not  necessarily  a  sign  of  typhoid  fever, 
since  the  eruption  may  occur  in  other  febrile  conditions. 
He  suggests  that  possibly  the  eruption  is  due  to  some 
derangement  of  the  cutaneous  secretion. 

A  Point  in  the  Differential  Diagnosis  of  Variola 
AND  Varicella. — Dr.  C.  Bareggi  withdrew  a  little  of  the 
fluid  contents  of  variolous  papules  and  pustules,  and 
having  made  dry  preparations  in  the  ordinary  way,  and 
stained  them  with  methylene  blue,  examined  them  under 
the  microscope.  He  found  large  numbers  of  cocci,  like 
those  described  by  Klebs  as  characteristic  of  variola. 
The  author  was  unable  to  find  these  microbes  in  papules 
or  pustules  of  any  other  origin.  They  were  absent  in 
chicken-pox,  which  fact  would  tell  against  the  theory  of 
the  identity  of  varicella  and  variola,  and  might  also  be 
of  value  in  the  differential  diagnosis  of  these  two  dis- 
eases.— Centralblatt  fur  Klinische  Medicin,  No.  38, 1884. 


7o8 


THE  MEDICAL  RECORD. 


[December  27,  1884 


The  Medical  Record: 


A  Weekly  yournal  of  Medicine  and  Surgery. 


GEORGE  F.  SHRADY,  A.M.,  M.D.,  Editor. 


Published  by 
WM.  WOOD  &  Co.,  Nos.  56  and  68  Lafayette  Place. 

New  York,  December  27,  1884. 

IS  BLOOD-TRANSFUSION  JUSTIFIABLE? 

The  history  of  transfusion  illustrates  very  forcibly  the 
quick  rise  and  fall  in  popularity  of  measures  that  do  not 
rest  on  the  sure  basis  of  exact  knowledge.  It  is  within 
the  memory  of  even  the  younger  members  of  the  med- 
ical profession  that  the  transfusion  of  blood  was  regarded 
as  one  of  the  most  important  operations  of  modern  sur- 
gery. Of  scarcely  a  single  other  procedure  was  it  said 
with  such  positive  assurance  that  it  constituted  a  grand 
life-saving  triumph  of  the  healing  art.  Yet  to-day  blood- 
transfusion  is  about  to  be  relegated  by  unerring  science 
to  that  still  extending  limbo  of  futile,  if  not  harmful  sur- 
gical interference.  Professor  v.  Bergmann  (London  Med- 
ical Record^  November  15,  1884)  *  has  recently  published 
a  critical  survey  of  the  entire  subject,  but  more  particu- 
larly of  the  history  of  transfusion  within  the  past  decade. 
He  starts  out  with  some  general  observations  concerning 
the  commendable  prevalence  among  physicians  of  habits 
of  keen  inquiry  and  searching  investigation.  The  practical 
and  fruit-bearing  discoveries  in  modern  medicine — espe- 
cially as  regards  surgery — rest,  he  thinks,on  the  safe  foun- 
dation of  biological  knowledge.  This  is  as  it  should  be 
For  whenever  serious  medical  action  does  not  conform, 
to  what  is  really  known,  mistakes  are  sure  to  happen. 
Transfusion  shows  this  very  well.  The  author  recalls  the 
fact  that  centuries  before  physicians  had  any  knowledge 
of  the  circulation  of  the  blood,  they  tried  by  this  bold 
measure  to  supply  new  vital  fluid  to  the  human  body. 
According  to  the  then  prevalent  idea,  blood  was  equiva- 
lent to  life  and  soul.  Almost  complete  ignorance  of  the 
true  function  of  blood  made  them  attribute  to  that  fluid 
all  the  mysterious  manifestations  of  life. 

It  is  not  surprising,  therefore,  that  we  find  in  the  seven- 
teenth century  not  only  individual  physicians,  but  whole 
colleges  and  other  learned  bodies,  seriously  discussing 
the  question  whether  a  dog  would  get  wool  and  horns  af- 
ter taking  sheep^s  blood,  and  whether  the  disposition  of 
sanguine  or  choleric  persons  could  not  be  improved 
through  the  agency  of  gentle  lamb's  blood.  Transfusion, 
it  was  also  thought,  could  rejuvenate  the  aged.  The  in- 
troduction of  the  blood  of  one  animal  into  the  circula- 
tion of  another  was  carried  out  in  a  variety  of  ways  in 
the  eighteenth  century.  Experience  gained  by  this  means 
showed  that  an  animal  nearly  dead  from  loss  of  blood 
may  be  resuscitated,  at  least  for  the  time  being.     But 

>  Die  Schicksale  der  Transfusion  im  letzten  Decennium.  Berim,  1883. 


human  transfusion  was  rarely  done  until  about  the  second 
half  of  our  century,  when  for  a  short  period  it  suddenly 
rose  to  rather  startling  frequency.  The  operation  was 
not  confined  to  cases  of  sudden  loss  of  blood.  On  the 
contrary  it  was  often  performed  for  all  kinds  of  acute 
and  chronic  diseases.  Patients  were  also  bled  to  rid 
them  of  vitiated  blood,  and  thus  prepare  them  for  the  in- 
troduction  of  healthy  fluid.  Pulmonary  and  renal  affec- 
tions, dyspepsia,  pyasmia,  typhus,  and  cholera  were  treated 
by  this  method.  No  wonder,  then,  that  grave  mistakes, 
often  fatal  in  their  consequences,  soon  brought  transfu- 
sion into  discredit. 

In  1859,  its  successful  employment  by  Martin,  of  Ber- 
lin, in  lying-in  cases,  once  more  revived  its  popularity, 
until  about  ten  years  ago  it  was  looked  upon  as  a  univer- 
sal panacea  for  the  greatest  variety  of  human  ailments. 
But  to-day  this  kind  of  unstinted  enthusiasm  has  died  a 
natural  death.  The  more  or  less  complicated  apparatus 
of  the  transfusionist  has  been  quite  generally  set  aside. 
Perhaps  it  will  soon  be  found  only  among  the  historical 
relics  of  a  past  era  in  medicine.  Certain  it  is  that  we 
know  much  more  about  haematology  than  we  did  even  a 
few  years  ago.  And  the  mistakes  that  have  been  asso- 
ciated with  the  practice  of  transfusion  arc  not  likely  to 
be  again  repeated. 

In  any  great  and  sudden  loss  of  blood,  the  arterial 
blood-pressure  sinks  so  low  that  the  movement  of  the 
blood  is  stopped.  F  or  a  time  the  heart  still  works  on,  but 
ineffectually.  It  is  like  an  empty  pump,  and  ceases  to  draw 
and  propel  the  column  of  blood.  In  the  vascular  system 
there  is  stagnation.  Were  the  blood  which  the  vessels 
still  contain  put  again  into  motion,  it  would  be  sufficient 
to  support  life.  Hence,  as  Kronecker  first  pointed  out, 
in  such  cases  a  simple  infusion  of  a  saline  solution  is 
sufficient  to  save  life.  By  this  means  the  contents  of  the 
vascular  system  become  increased  in  volume.  This  in« 
tensifies  the  intra-vascular  pressure  and  re-establishes  the 
working  of  the  heart.  Now  we  understand  why  in  so 
many  cases  transfusion  has  saved  life  ;  why  Lower's  and 
Boyle's  rudimentary  experiments  on  dogs  were  success- 
ful. What  was  required  was  to  fill  the  elastic  tubes  of 
the  vascular  system  with  fluid,  not  necessarily  with  blood. 

Again,  after  considerable  loss  of  blood  the  proportion 
of  blood-corpuscles  remaining  in  the  blood  becomes  less 
and  less,  and  for  a  variable  time  after  the  bleeding  has 
ceased  the  diminution  still  goes  on.  Subsequently  to 
the  transfusion  of  a  large  quantity  of  blood  the  blood- 
corpuscles  seem  to  be  increased,  but  only  for  a  rime. 
Very  soon  their  number  diminishes,  while  the  urea  and 
alkaline  elements  of  the  urine,  and  the  deepened  color  of 
the  latter,  betoken  the  ruin  and  disintegration  of  the 
blood  and  its  corpuscles,  which  have  been  conducted  in 
excess  into  the  system. 

The  scientific  study  of  the  subject  was  much  advanced 
by  the  counting  of  blood-corpuscles,  but  even  more  so 
by  the  results  of  the  direct  transfusion  of  animal  blood 
Supported  by  the  apparently  remarkable  cures  of  Hasse, 
it  quickly  became  a  favorite  measure.  It  seems  scarcely 
credible  how  tenaciously  physicians  clung  to  this  form  of 
the  operation  even  up  to  the  close  of  the  last  decade. 

After  every  transfusion  with  lamb's  or  dog's  blood,  the 
patients  develop  a  series  of  morbid  symptoms.  First  there 
is  dyspnoea,  followed  by  a  feeling  of  being  over-full,  then 


December  27,  1884.] 


THE   MEDICAL  RECORD. 


709 


sickness,  and  afterward  sinking  and  uncontrollable  stool- 
pressure.  There  are  also  headache,  dizziness,  and  even 
short  periods  of  unconsciousness.  From  ten  minutes  to 
an  hour  after  the  transfusion  a  chill  will  set  in,  often  in- 
creasing to  a  violent  shivering  fit,  then  a  stage  of  heat, 
with  very  high  temperature.  The  haemaglobinuria  al- 
ready mentioned  is  the  direct  result  of  the  dissolution  of 
red  blood-corpuscles.  We  can  scarcely  understand  •  to- 
day how  many  observers,  in  the  face  of  such  serious  dis- 
turbances, could  disregard  the  manifold  dangers  of  trans- 
fusion with  foreign  blood.  Their  only  apparently  justifiable 
reason  seems  to  have  been,  that  one  case  after  another 
of  transfusion  with  lamb's  blood  seemed  to  be  successful, 
or  more  correctly  speaking,  that  the  patients  did  not 
quite  die. 

The  injurious  effects  of  transfusion  with  foreign  blood 
were  attributed  by  Prevost  and  Dumas  to  the  unequal 
size  of  the  blood-corpuscles  in  different  kinds  of  animals. 
As  the  blood-corpuscles  of  a  sheep  are  smaller  than 
those  of  man,  they  were  considered  harmless.  To  Pon- 
fick  must  be  given  the  credit  of  showing  how  erroneous 
this  was.  It  is  not  the  mechanism  of  the  different-sized 
corpuscles  that  makes  foreign  blood  injurious,  but  rather 
important  chemical  changes,  which,  when  a  certain  quan- 
tity is  transfused,  makes  the  blood  of  a  sheep  a  deadly 
poison  to  a  dog,  and  vice  versa.  A  complete  answer 
has  been  given  to  the  question  as  to  what  the  harmfiil- 
ness  of  foreign  blood  consists  in.  And  henceforth,  v. 
Bergmann  thinks,  this  kind  of  transfusion  should  disap- 
pear from  the  stock  of  surgical  remedies. 

Long  before  Panum  pressed  upon  the  attention  of  phy- 
sicians transfusion  with  defibrinated  blood,  Magendie  had 
found  by  his  experiments  on  animals  that  su;:h  blood 
caused  decided  disturbances,  such  as   quick  breathing, 
diarrhoea  with  tenesmus,  and  bloody  effusions  into  the 
peritoneal,  pericardial,  and  pleural  sacs.     Accordingly, 
he  warned  the  profession  against  its  use.     It  is  easy  to 
understand  why  physicians  did  not  altogether  follow  him, 
because  in  direct  transfusion  there  are  the  namerous 
risks  of  coagulation  attending  the  use  of  syringes  and 
canulse.   Virchow,  in  his  work  on  "  Thrombosis  and  Em- 
bolism," did  not  in  connection  with  transfusion  set  forth 
these  dangers,  or  else  he  under-estimated  them.     At  the 
present  moment,  they  form  the  principal  objection  to 
the  only  permissible  form  of  blood-transfusion,  namely, 
that  with  human  ];)lood  intact. 

The  idea  of  plethora  with  increased  blood-pressure 
after  transfusion  for  the  cure  of  certain  diseases  gave 
rise  to  the  practice  of  bleeding  the  patient  before  the  op- 
eration. Especially  in  treating  septicaemia  in  this  way, 
a  large  quantity  of  blood  was  taken  from  the  patient  in 
order  that  it  might  be  replaced  with  new  blood  ;  doubt- 
less a  double  injury  to  the  patient,  first  by  the  blood-let- 
ting, and  secondly  by  the  transfiision.  These  operations 
nearly  always  proved  fatal.  But,  at  any[rate,  they  showed 
the  non-existence  of  increased  blood-pressure  as  a  cause 
of  the  fatal  ending. 

Whenever  transfusion  with  blood  has  saved  life,  it  has 
done  so  by  starting  a  sluggish  or  stagnating  blood-cur- 
rent to  quicker  motion,  and  not  through  any  reviving 
respiratory  action  of  the  blood-corpuscles.  It  is  owing 
to  two  things  that  transfusion  has  often  passed  off  with- 
out   danger,  and  has  even  been  endured  without  much 


disturbance.  The  first  is  the  small  quantity  of  blood, 
usually  not  much  exceeding  one  ounce,  that  was  em- 
ployed. With  this  they  tried  to  cure  phthisis,  chlorosis, 
and  chronic  intestinal  catarrh.  The  second  is  the  power 
of  resistance  of  the  organism  against  the  effects  of  the 
fibrine-ferraent.  If,  however,  transfusion  carries  with  it 
grave  dangers,  we  are  forced  to  the  conclusion  that  we 
are  on  the  wrong  track.  All  that  can  be  effected  by  the 
operation  can  be  effected  by  other  and  simpler  means, 
namely,  by  infusing  into  the  veins  a  solution  of  common 
salt  It  has  been  established  by  numerous  cases  that, 
when  transfusion  of  a  solution  of  common  salt  is  used  it 
revives  the  patient  and  causes  the  heart  to  beat.  It  is 
conceivable  that  a  patient  may  be  revived  by  something 
injurious.  But  if  it  can  be  done  by  something  that  is 
harmless,  we  should  welcome  the  latter.  There  is  only 
one  kind  of  blood-transfusion  that  can  really  be  justified : 
the  transfusion  of  blood  from  the  artery  of  one  man  di- 
rectly into  the  vein  of  another. 

Experiments  have  been  made  to  convey  fluids  to  the 
blood  by  other  means  than  transfusion.  But  they  have 
proved  barren  of  lasting  benefits.  Thus,  when  it  became 
known  that  fluids  are  sometimes  rapidly  absorbed  by  the 
peritoneum,  the  attempt  was  made  to  replace  transfusion 
by  flooding  the  peritoneal  cavity  with  defibrinated  blood.. 
The  lymphatics  seemed%to  eagerly  absorb  notable  quan- 
tities of  it.  But  haematic  icterus  resulted,  and  the  urine 
soon  showed  the  presence  of  uro-obilin.  Intraperito- 
neal transfusion  is,  therefore,  unjustifiable. 

If  we  accept  v.  Bergmann's  teaching,  and  certainly  he 
makes  out  a  strong  case,  it  would  seem  that  blood-trans- 
fusion is  really  a  thing  of  the  past.  On  the  other  hand, 
the  introduction  of  some  saline  solution  into  a  vascular 
system  threatened  with  profound  stagnation,  would  be  a 
substitute  that  is  free  from  the  manifold  dangers  insepar- 
able from  the  older  method  of  transfusion. 


THE  ATTACK  UPON  DR.  FORDYCE  BARKER. 

It  is  witli  the  profoundest  regret  that  we  chronicle  the 
proceedings  of  the  New  York  Academy  of  Medicine  of 
last  week.  The  wanton  attack  upon  the  venerable 
President  furnished  an  exhibition  of  impotent  spite  and 
stupid  malevolence  quite  without  parallel  in  the  medical 
annals  of  this  city.  A  distinguished  physician,  who  has 
practised  his  profession  blamelessly  for  thirty  years,  whose 
high  qualities  of  character  have  drawn  about  him  an 
ever-increasing  troop  of  fiiends,  whose  professional  at- 
tainments have  won  for  him  the  most  ^distinguished 
honors  at  home  and  abroad,  who  has  been  justly  looked 
upon  as  one  of  the  best  types  of  American  physicians, 
and  who  in  his  later  years  has,  by  self-sacrificing  and 
assiduous  efforts,  raised  the  Academy  of  Medicine  to  be 
the  foremost  medical  society  of  the  country — this  man  is 
at  last  made  the  victim  of  a  baseless  charge  that  he  has 
been  a  life-long  hypocrite,  that  he  is  not  legally  a  doc- 
tor !  The  infinite  pettiness  of  mind  which  could  trump 
up  these  accusations,  so  easily  proved  false,  is  quite  past 
comprehension. 

Neither  can  we  understand  how  men,  who  have  been 
posing  as  representatives  of  a  high  professional  morality, 
should  so  [blindly  give  the  lie  to  their  pretensions  by 
devising  and  giving  publicity  to  a  contemptible  slander 


yio 


THE  MEDICAL  RECORD. 


[December  27, 1884. 


upon  a  brother  physician ;  for  it  is  not  alone  that  the 
character  of  Dr.  Barker  was  impudently  assailed— that 
gentleman  has  been  too  long  known  and  too  widely 
honored  to  be  harmed  by  the  slander  brought  against  him — 
but  the  profession  itself  has  been  injured  by  the  publicity 
given  to  a  disgraceful  and  unnecessary  quarrel. 

The  medical  profession  at  large  will  hear  and  judge 
who  best  represents  the  true  standard  of  professional 
honor.  Dr.  Fordyce  Barker  or  those  who  have  again  so 
wantonly  fomented  discord,  excited  bitterness  of  feeling, 
exposed  our  dissensions  to  the  world,  and  maliciously 
attempted  to  injure  a  physician  than  whom  no  one  more 
deserves  to  be  honored  at  our  hands. 


THE  THERAPEUTICAL  VALUE   OF  ELECTRICITY. 

Two  papers  of  interest,  by  Dr.  Hughes  Bennett  and  Dr. 
W.  E.  Steavenson,  respectively,  were  read  at  the  last 
meeting  of  the  British  Medical  Association.  They  treated 
of  the  somewhat  hackneyed  subject  of  electro-thera- 
peutics, but  the  points  made  in  them  and  the  discussion 
which  followed  drew  out  some  thoughts  which  deserve 
attention.  They  showed  for  one  thing  that  in  England 
as  in  this  country  the  general  practitioner  knows  very 
little  about  electricity,  and  does  not  trouble  himself  with 
ij  much  in  his  daily  practice.  Further,  Dr.  Steavenson 
expressed  the  opinion  that  the  cost  of  an  electro-thera- 
peutical "plant,"  the  expense  of  keeping  it  in  order,  and 
the  time  occupied  in  applying  electricity  would  in  time 
throw  a  large  part  of  electro-therapeutical  work  into  the 
hands  of  specialists,  or  of  electricians  who  would  rank 
with  cuppers  and  masseurs,  doing  just  what  was  directed 
and  no  more. 

Such  an  arrangement  will  be  slow  to  occur  in  this 
country  because,  even  if  it  were  desirable,  our  sick  pop- 
ulation is  too  scattered  to  support  "  electricians,"  except 
in  the  large  cities. 

Nevertheless,  there  is  unquestionably  a  tendency  in 
this  direction  of  electro-therapeutical  specialization. 
Physicians  in  general  practice,  who  have  batteries,  and 
who  know  perchance  how  to  use  them,  are  generally  too 
busy  to  make  applications  as  they  should  be  made.  A 
call  of  ten  minutes  must  be  extended  to  half  or  three- 
quarters  of  an  hour,  and  his  patient  will  not  pay  him  in 
proportion  to  the  time  expended.  The  consequence  is 
that  nine  out  of  ten  of  the  medical  batteries  of  the  gen- 
eral practitioners  throughout  the  country  are  at  the  pres- 
ent moment  rusting  in  the  closet,  the  fluid  evaporated, 
and  the  zincs  eaten  up. 

But  there  is  a  wide-spread  belief  among  the  commune 
vulgus  that  "  electricity  is  life.'*  The  buzz,  the  thrill, 
and  the  flashes  of  the  battery  sustain  this  biological  con- 
viction, warm  the  imagination,  and  excite  confidence  and 
hope,  even  if  they  do  not  really  cause  a  cure.  The 
doctor  must  often  have  a  battery  to  satisfy  his  patient ; 
and  he  can  actually  help  him  by  its  psychical  effects. 

There  is  probably  a  steady  increase  in  the  use  of  elec- 
tricity among  American  physicians.  Instrument-makers 
inform  us  that  they  sell  more  batteries  every  year.  An 
intelligent  knowledge  of  what  electricity  will  do  has  not, 
however,  kept  pace  with  the  highly  profitable  industry  of 
making  and  mending  batteries. 

Consequently  electro-therapeutics  in  the  hands  of 
many  touches  on  the  borders  of  charlatanry.     The  claims 


made  for  it,  even  by  reputable  physicians,  are  often  pre- 
posterous. Absurd  theories  as  to  its  action  are  ad- 
vanced, and  its  practical  applications  are  made  without 
discrimination  or  skill. 

Those  who  have  written  most  carefully  and  conscien- 
tiously  upon  electro-therapeutics  have  shown  that  its 
usefulness  is  more  limited  than  was  first  believed,  but  that 
within  its  limits  it  has  a  remedial  power  which  is  un- 
equalled. Scientific  investigation  has  also  shown  that 
electricity  in  diagnosis  gives  us  a  precision  and  help  at- 
tainable in  no  other  way ;  and  electro-diagnosis'is  a  field 
which  charlatanry  does  not  care  to  touch. 

In  practical  medicine  electricity  is  of  most  value  as  a 
counter-irritant,  a  mechanical  stimulant  and  a  general 
tonic.  In  rheumatic  pains  and  certain  forms  of  neural- 
gia and  in  functional  asthenic  states  it  does  its  best  work. 
In  paralysis  it  is  a  mere  symptomatic  remedy,  much  over- 
rated, and  generally  disappointing.  Its  power  to  modify 
in  the  slightest  degree  organic  cerebro-spinal  diseases  is  a 
thing  still  subjudice. 

The  teachers  of  medicine  in  our  medical  colleges  are 
generally  men  who  are  too  busy  to  use  electricity,  and 
consequently  they  know  little  about  it,  even  its  diagnostic 
value.  It  would  be  a  wise  thing  for  the  colleges  to  give 
more  of  practical  instruction  regarding  the  subject,  if  only 
to  warn  students  against  in  future  *'  listening  with  cre- 
dulity to  the  whispers  of  fancy  or  pursuing  too  eagerly 
the  phantoms  of  hope." 

Successful  and  honest  electro-therapy  means  an  Ex- 
penditure of  money,  time,  and  skill. 

Dishonest,  though  perhaps  successful,  electro-therapy 
means  the  indiscriminate  buzzing  of  a  vibrator  in  the  ears 
of  every  credulous  and  hypochondriacal  visitor. 


THE  VALUE  OF  LOCAL  MEDICAL  JOURNALS. 

A  Southern  contemporary  complains  that  Southern  men 
subscribe  for  Northern  journals,  but  that  Northern  men 
do  not  subscribe  for  Southern  journals.  Granting  that 
this  is  true,  we  would  say  to  our  Southern  brother  that 
men  will  go  where  they  can  get  the  most  and  the  best  for 
their  money,  and  that  no  complaints  or  grumbling  can 
alter  the  law  of  supply  and  demand.  Medicine  is  a  cos- 
mopolitan science — it  knows  no  South  or  East  or  West 
The  human  race  is  one,  and  the  laws  governing  its  dis- 
eases are  the  same  everywhere.  An  inflammatioD,  a 
cancer,  a  colic,  affect  alike  Hindoo,  Hottentot,  and,  in 
all  respect,  our  Southern  medical  editor.  The  true  phy- 
sician, therefore,  will  encourage  whatever  tends  best  to 
help  along  his  science  and  art,  and  will  not  hamper 
progress  for  the  sake  of  gratifying  local  pride. 

At  the  same  time,  we  fully  believe  in  the  great  value 
of  local  medical  journals,  and  would  urge  their  generous 
support  (if  they  are  worthy)  by  the  profession.  For  it  is 
true  that  somewhat  different  diseases  prevaU  in  one 
country  from  those  in  another,  and  that  race,  climate, 
and  other  factors  may  modify  slightly  the  physiognomy 
of  the  same  disease.  Local  journals  may  be  of  service 
in  interpreting  these  differences.  But,  more  than  that, 
the  local  medical  journal  has  an  important  function  in 
uniting  the  physicians  of  a  State,  in  making  them  known 
to  each  other,  and  in  organizing  and  helping  forward 
movements  for  the  improvement  of  the  profession. 

If  our  contemporary  would  ask  for  support  upon 


December  27,  1884.] 


THE  MEDICAL  RBCORD. 


711 


grounds  such  as  these,  instead  of  appealing  to  sectional 
prejudice  and  complaining  of  others'  success,  it  would 
doubtless  receive,  and  would  certainly  deserve,  a  hearty 
response. 

THE  NEW  YORK  ACADEMY  OF  MEDICINE. 

It  must  now  be  apparent  to  all  that  hostility  to  this  most 
important  institution  has  been  nearly  as  strong  a  moving 
force  in  causing  the  recent  attempt  of  a  half-dozen  mal- 
contents as  the  bitter  hatred  of  its  President.  Very 
many  who  were  dragooned,  by  specious  pretence  and 
plausible  fallacies,  to  attend  the  meeting  of  the  Academy 
in  April,  1883,  and  vote  for  a  measure  which  would  have 
stopped  its  work  and  its  usefulness,  from  the  conviction 
that  they  were  thus  doing  their  best  to  maintain  the 
National  Code,  have  expressed  not  only  their  regret  but 
their  deep  disgust,  when  they  have  come  to  see  that  they 
were  not  working  for  principle  but  for  the  gratification 
of  personal  malice.  The  few  words  from  the  President, 
on  resuming  the  chair,  tell  the  whole  story,  and  were  so 
devoid  of  personal  feeling,  and  in  such  excellent  taste, 
that  we  deem  them  worthy  of  being  again  repeated  in 
this  connection  :  **  The  Academy  will  now  resume  its 
scientific  work,  which  it  has  so  zealously,  efficiently,  and 
harmoniously  carried  on  for  thirteen  months,  until  now 
interrupted  by  this  supreme  effort  to  elevate  the  char- 
acter of  the  medical  profession." 


THE  MEDICAL  PROFESSION  OF  THIS  CITY. 

The  question  is  often  asked  by  those  from  other  parts  of 
the  country,  *'  How  is  it  that  such  fights  axh  going  on  in 
your  city,  which  shock  us  who  do  not  comprehend  them  ? 
There  is  the  same  diversity  of  opinion  in  regard  to  the 
necessity  and  utility  of  the  National  Code  as  with  you, 
but  it  has  never  assumed  such  proportions  as  with  you. 
It  does  not  break  personal  friendship,  nor  do  any  of  us 
think  that  sound  ethics,  the  honor  of  the  profession,  or 
its  standing  in  the  community,  can  be  best  promoted  by 
personal  abuse,  detraction,  or  calumny."  Some  good 
always  comes  out  of  evil.  The  reproach  will  now  be 
wiped  out.  The  audacity  of  four  or  five,  in  assuming  to 
be  leaders  of  the  City  and  State  in  all  active  movements, 
speciously  but  avowedly  for  the  support  of  the  National 
Code,  has  now  shown  them  to  be  the  most  notorious  and 
conspicuous  violators  of  its  spirit.  The  President  of  the 
Academy  has,  and  always  has  had,  as  warm  friends  in  this 
city  among  the  avowed  advocates  of  the  Old  as  of  the 
New  Code.  In  other  cities  and  other  parts  of  the  coun- 
try it  is  probable  that  a  majority  of  the  prominent  men 
in  the  profession,  who  are  his  friends,  are  pronounced 
advocates  of  the  Old  Code.  The  mask  of  honest  pur- 
pose has  now  been  torn  away  from  such  dangerous 
leaders,  and  the  true  visage  of  implacable,  unrelenting, 
and  unprincipled  malignity  has  been  revealed  in  all  its 
hideousness.  We  feel  assured  that  among  the  two 
thousand  (?)  physicians  of  this  city  and  Brooklyn  not 
fifty  can  be  found  who  are  not  in  hearty  accord  with  this 
view. 

It  is,  perhaps,  worthy  of  mention  that  not  one  of  the 
leaders  in  the  recent  events,  which  have  so  stirred  the 
profession  of  this  city,  is  known  as  an  active,  much  less 
as  a  prominent,  practitioner  of  medicine. 


BELLEVUE  HOSPITAL  MEDICAL  COLLEGE. 

The  announcement  of  the  Faculty  of  this  College  for 
two  years  past  has  conspicuously  inserted  this  sentence  : 

**  The  standard  of  Medical  Ethics  recognized  by  the 
College  is  embodied  in  the  Code  of  Ethics  of  the  Ameri- 
can Medical  Association." 

No  other  colleges,  so  far  as  we  have  noticed,  have  felt 
it  necessary  thus  to  advertise  their  goodness.  It  was  a 
novel  bid  for  students.  As  a  matter  of  taste,  it  seems  as 
absurd  as  it  Would  be  for  a  lady  of  good  social  position 
and  unblemished  character  to  inform  all  that  she  met 
that  she  was  virtuous. 

It  was  undoubtedly  believed  to  be  a  politic  move ; 
whether  it  has  proved  so  or  not  can  only  be  determined 
by  comparing  the  number  of  students  of  two  years  past 
with  the  number  the  two  years  before,  and  also  compar- 
ing these  numbers  with  those  in  the  two  other  colleges 
of  this  city  during  the  same  period. 

But  the  question  is  now  asked,  whether  this  standard 
is  intended  to  apply  only  to  students,  or  is  to  have  equal 
force  in  regulating  the  Faculty.  Tacit  acquiescence  in 
the  conduct  of  one  of  their  number,  who,  by  his  extraor- 
dinary and  unparalleled  efforts  as  a  volunteer  police 
detective  in  a  foreign  country,  obtained  a  kind  of  nega- 
tive evidence  which  would  never  have  been  admitted  81 
any  court  of  law  in  proof  of  a  charge,  but  would,  if  not 
refuted,  have  a  kind  of  moral  force  to  tarnish  the  reputa- 
tion of  another  member,  who  is  at  least  the  peer  of  any 
member  of  the  Faculty,  will  answer  the  question.  If  the 
Faculty  are  in  doubt  in  regard  to  the  matter,  they  may 
perhaps  study  with  profit  a  very  able  commentary  on 
Ethics  by  another  of  their  number,  which  first  appeared 
in  the  New  York  Mediccd  Journal^  and  was  afterward 
published  in  a  separate  volume. 


THE   FIRST   TOTAL    REMOVAL  OF   THE  CEREBELLUM 
IN  A  DOG. 

Professor  Luciani  has  succeeded,  by  infinite  care  and 
the  strictest  application  of  modern  surgical  principles,  in 
totally  removing  the  cerebellum  of  a  dog  without  destroy- 
ing life.  This  single  success  seems  likely  to  sweep  away  a 
world  of  carefully  built  hypotheses  regarding  the  function 
of  the  cerebellum.  During  the  stage  of  healing  and  irri- 
tation incoordination  symptoms  appear,  similar  to  those 
usually  observed  in  birds.  As  recovery  advances,  how- 
ever, these  disappear,  and  a  kind  of  muscular  asthenia  or 
loss  of  tone  takes  its  place. 

The  experiment  confirms  apparently  the  views  of  Her- 
bert Spencer,  Jackson,  and  Ross,  as  to  the  **  tonic  "  in- 
nervation of  the  muscles  by  the  cerebellum. 

The  description  of  the  effects  of  the  operation  is  well 
given  in  the  British  Medical  Journal^  which  says  : 

'<  When  healing  is  finished,  the  so-called  inco-ordination 
(contractures  and  pseudo-paralytic  debility)  disappears, 
the  animal  can  walk  for  longer  and  longer  distances  with- 
out falling.  What  strikes  the  observer  is  the  deficient 
proportion,  firmness,  and  tone  of  the  individual  muscular 
contractions,  and  their  want  of  fusion  ;  in  a  word,  a  kind 
of  'cerebellar  ataxy,'  difficult  to  describe  accurately. 
This  disorder  of  the  movements  is  not,  as  the  '  inco-ordi- 
nation '  of  the  first  period,  sufficiently  serious  to  prevent 
the  animal  from  effecting  its  various  voluntary  acts ;  and. 


712 


THE  MEDICAL  RECORD. 


[December  27,  1884. 


upon  closer  investigation,  resolves  itself  into  a  kind  (not 
of  paralysis  nor  paresis,  but)  of  motor  '  asthenia.'  For 
instance,  if,  instead  of  walking,  the  dog  were  made  to 
swim  in  a  pond,  then  its  movements  were  perfectly  nor- 
mal Not  the  least  sign  of  want  of  equilibration  was  no- 
ticeable ;  the  four  limbs  acted  with  ease,  the  animal  being 
propelled  in  the  water  just  as  it  had  been  noticed  to  do 
before  the  operation,  showing  a  full  co-ordination  and 
adaptation  of  the  individual  movements  necessary  to  the 
performance  of  the  action.  But,  on  arriving  at  the  edge 
of  the  pond,  the  dog  was  unable  to  get  a  footing,  in  spite 
of  its  efforts.  Professor  Luciani  lays  stress  upon  the 
great  difference  between  the  normal  behavior  of  the  dog 
while  swimming,  and  its  disturbed  motility  when  perform- 
ing acts  requiring  a  greater  development  of  muscular 
energy ;  and  concludes  .that  the  *  cerebellar  ataxy '  just 
described,  is  merely  a  manifestation  of  a  kind  of  motor 
asthenia,  that  is  to  say,  of  the  insufficient  muscular  tone, 
or  influence  exercised  by  the  nerve-centres  upon  the  vol- 
untary muscles." 

THE  ALLEGED  "VACCINE"  AGAINST  YELLOW  FEVER. 

The  Daily  Times  gives  as  news  some  account  of  the  dis- 
coveries of  Dr.  Domingos  Freire  regarding  the  discovery 
•f  a  yellow  fever  germ  and  yellow  fever  vaccine ;  and 
our  contemporary  wonders  why  the  discoveiy  does  not 
attract  more  attention.  Some  of  our  medical  contem- 
poraries have  also  been  heralding  the  discovery  as  some- 
thing very  new.  The  fact  is,  however,  that  Dr.  Freire 
wrote  a  very  full  account  of  his  work  to  the  Sanitary 
News  several  months  ago,  and  long  before  M.  Bouley 
presented  the  subject  to  the  Academic  de  M^icine.  At 
an  earlier  time  we  gave  an  abstract  of  his  conclusions, 
and  added  the  opinion,  which  we  still  hold,  that  Dr. 
Freire  has  yet  to  win  a  reputation  as  a  trustworthy  ob- 
server. Some  of  his  previous  "  discoveries "  in  bacteri- 
ology have  turned  out  to  be  no  discoveries  at  all. 


THE  \.  C.  E.   MIXTURE,  NITROUS  OXIDE,  AND  ETHER. 

In  one  of  the  periodical  discussions  upon  anaesthetics 
which  recently  took  place  before  the  London  Medical 
Society,  some  more  than  ordinarily  useful  facts  and  con- 
clusions were  drawn  out.  These  may  be  formulated  as 
follows : 

First, — British  surgeons  are  giving  up  the  routine  use 
of  chloroform,  except  perhaps  with  children. 

Second, — The  A.  C.  E.  mixture  was  shown  to  be  safer 
than  chloroform,  and  almost  as  safe  as  ether,  while  more 
convenient.  This  mixture  is  composed  of  one  part,  by 
measure,  of  alcohol  to  two  parts  (measured)  of  chloro- 
form and  three  of  ether.  This  mixture  should  be  made 
afresh  just  before  being  required  for  use.  A  drawback 
to  its  employment,  though  a  small  one,  is  that,  in  prac- 
tice, it  is  found  to  act  a  little  less  rapidly  than  chloro- 
form in  the  production  of  insensibility.  It  requires  no 
complicated  apparatus  for  its  use,  being  doled  out  drop 
by  drop  on  a  napkin ;  and,  as  an  accumulating  experi- 
ence of  many  years  in  several  metropolitan  hospitals 
appears  to  testify,  it  is  superior  in  point  of  safety  for 
adult  patients  to  chloroform  alone.  The  exhilarating 
effects  of  the  three  parts  of  ether  appear,  in  practice,  to 


counterbalance  the  properties  of  the  two  parts  of  chloro- 
form as  a  cardiac  depressor. 

One  surgeon,  Mr.  Estes,  uses  chloroform  for  young 
children  and  the  A.  C.  E.  mixture  for  persons  between 
the  ages  of  six  and  eight  and  sixteen  and  eighteen. 

Third, — For  safety  no  anaesthetics  equal  ether  and 
nitrous  oxide. 

Fourth, — For  both  safety  and  rapidity,  no  other  anaes- 
thetics equal  nitrous  oxide  gas  and  ether  given  together. 
The  only  objection  to  this  combination  appears  to  be 
connected  with  the  apparatus  that  has  to  be  employed. 
It  is  bulky,  and  demands  a  larger  initial  outlay  than 
practitioners  throughout  the  country,  who  seldom  require 
to  administer  ansesthetics,  would  be  disposed  to  incur. 
Still,  for  all  who  can  employ  them,  nitrous  oxide  used 
with  ether  possess  advantages  not  found  in  any  other 
single  anaesthetic  agent,  or  combination  of  agents,  at  the 
present  day  known. 

%zms  tit  titje  '^SSLtt\i. 

Medico-Legal  Science  in  New  York  City.— At  the 
last  meeting  of  the  New  York  Medico-Legal  Society, 
Professor  R.  Ogden  Doremus  was  elected  President 
At  the  last  meeting  of  the  Society  of  Medical  Jurispni- 
prudence.  Dr.  Frank  H.  Hamilton  was  elected  Presi- 
dent. Both  of  these  Societies  have  been  working  hard 
during  the  past  year,  and  have  succeeded  in  attracting  a 
good  deal  of  attention  to  medico-legal  subjects.  The 
Society  of  Medical  Jurisprudence  is  the  result  of  a  pro- 
test against, 'and  a  "  bolt "  from,  the  Medical-Legal  So- 
ciety and  its  management ;  and  is  hampered  only  by  its 
youth.  The  Medico-Legal  Society  has  been  seriously, 
if  not  irretrievably,  injured  by  the  fatuous  ambition  of  a 
lawyer  who  seems  to  have  no  other  aim  in  life  than  to  be 
its  president  and  manager.  It  is  much  to  be  hoped  that 
under  Professor  Doremus  the  Society  may  regain  some 
of  its  lost  prestige. 

AsEPTOL,  A  New  Antiseptic,  says  M.  E.  Transer,  has 
for  its  scientific  name  orthoxyphenyl — sulphurous  acid 
It  is  an  acid  phenol,  capable  of  neutralizing  ammoniacal 
bases.  It  is  said  to  be  preferable  to  phenol  as  an  anti- 
septic, because  it  possesses  the  decided  advantage  0! 
not  being  poisonous. 

In  the  Death  of  Dr.  Edward  Jarvis,  which  oc- 
curred recently,  in  the  eighty-first  year  of  his  age,  the 
medical  profession  has  lost  one  of  its  most  useful  and  dis- 
tinguished members.  From  an  interesting  account  of 
his  life  in  the  Boston  Medical  and  Surgical  Journal^  we 
learn  that  Dr.  Jarvis  was  one  of  the  members  of  the  Cor- 
poration of  the  Perkins  Institution  for  the  Education  of 
the  Blind  ;  he  was  Superintendent  of  the  School  for  Fee- 
ble-Minded  Youths ;  Trustee  of  the  Worcester  Lunatic 
Hospital;  Consulting  Physician  to  the  New  England 
Hospital  for  Women  and  Children,  and  for  nearly  a  third 
of  a  century  President  of  the  American  Statistical  Asso- 
ciation. Dr.  Jarvis  was  the  earliest  petitioner  to  the 
Legislature  for  a  State  Board  of  Health.  He  labored 
year  after  year,  early  and  late,  for  its  establishment,  and 
he  did  his  best  to  support  it  by  zealous  work.  His  enu- 
meration of  the  insane  in  Massachusetts  (Report  of  1354), 


December  27,  1884.] 


THE  MEDICAL -^RECORD. 


713 


his  essays  on  political  economy,  social  science,  and  sta- 
tistics, and  his  valuable  contributions  i  to  the  United 
States  Array  Reports,  gave  him  well-deserved  reputa- 
tion as  a  statistician  in  this  country  and  in  Europe.  As  a 
kind-hearted  citizen  and  philanthropist.  Dr.  Jarvis  was 
ever  ready  with  sympathy  and  help  for  every  person  and 
good  cause  that  needed  them,  and  his  public  spirit  was 
shown  to  the  last  in  the  gift  of  his  valuable  collection  of 
books  and  reports  to  Harvard  College,  the  American 
Statistical  Association,  and  the  public  libraries  of  Con- 
cord and  Boston.  He  also  gave  $500  each  to  Harvard 
'  College  and  the  Statistical  Association. 

The  Ohio  State  Sanitary  Association  holds  its 
second  annual  meeting  at  Columbus,  O.,  February  5 
and  6,  1885.  The  Secretary  is  Dr.  R.  Harvey  Reed,  of 
Mansfield. 

Antipyrin  is  said  to  be  the  most  popular  of  i  *w 
antipyretics,  and  has  been  the  one  most  imported. 

The  First  Enucleation  of  the  Eye  Under  Co- 
caine.— Dr.  S.  A.  Hazen,  of  Youngstown,  O.,  writes  that 
Dr.  Davis,  of  the  same  place,  enucleated  an  eyfe  under 
cocaine  about  the  first  week  in  December^  and  was  the 
first  to  perform  that  operation  with  the  help  of  the  new 
anaesthetic  » 

Cultivation   op   Leprosy  Bacilli,  and   Vaccina- 
tion FOR  Leprosy, — We  learn  from  California  exchanges 
that  Hawaiian  physicians  have  been  studying  the  para- 
sitic origin  of  leprosy.     Experiments  are  being  carried  out 
with  the  bacillus,  and  an  efifort  has  been  made  to  culti- 
vate it,  so  that  vaccination  for  leprosy  may  be  practised. 
An  experiment  is  now  being  tried  in  the  case  of  a  con- 
demned criminal,  who  has  been  inoculated,  and  whose 
case  will  be  carefully  studied,  in  the  hope  that  something 
definite  may  be  learned  concerning  the  dread  disease. 
So  much  attention  has  been  given  to  the  subject  in  Hon- 
olulu, and  the  disease  is  spreading  so  fast,  that  the  white 
Ix>pulation  has  become   aroused  to    the   necessity   for 
doing  something  to  protect  themselves. 

Death  op  Dr.  Charles  Clay,  one  of  the  Revivers 
OF  Ovariotomy. — We  learn  that  Dr.  Charles  Clay,  of 
Manchester,  England,  has  recently  been  stricken  down 
by  paralysis  at  the  age  of  eighty-three,  and  is  not  ex- 
pected to  live.     Mr.  Lawson  Tait  writes  of  him :  "  So 
far  as  has  yet  been  discovered,  the  first  ovarian  tumor 
removed  in  England  was  by  the  hands  of  Dr.  Charles 
Clay,  on  September  27,  1842  ;  all  others,  with  the  ex- 
ception of  one  by  Houston,  and  another  by  Lizars,  in 
Scotland,  were  clearly  parovarian  cysts.     In  1843  ^^* 
Aston  Key  removed  both  ovaries,   and   Mr.    Bransby 
Cooper  also  tried  the  operation  in  that  year,  but  it  was 
not  till  1844  that  there  was  a  successful  case  in  London, 
operated  on*  by  Dr.  Frederick  Bird,  followed  by  one  in 
the  practice  of  Mr.  Lane.     In  the  provinces,  however, 
many  successful  cases  had  been  done.     In  June,  1848, 
X>r.  Charles  Clay  published  a  series  of  32  cases  with  10 
deaths,  and  in  1857  he  had  completed  77  cases  with  24 
deaths,  and  he  continued  to  operate  for  many  years,  un- 
til  he  had  performed  395  operations,  with  10 1  deaths, 
his  total  mortality  being  fractionally  above  twenty-five  per 
cent.     The  only  revival  of  ovariotomy  which  Sir  Spencer 
Wells  can  lay  any  claim  to,  is  after  its  temporary  decad- 
ence for  two  and  a  half  years  in  London  in  the  hands  of 


Mr.  Baker  Brown ;  and  even  upon  this  point  the  evi- 
dence is  by  no  means  satisfactory.  But  if  it  is  to  be  con- 
tended that,  firom  the  time  of  McDowell  till  1857,  there 
was  nothing  done  in  ovariotomy,  and  that  the  revival 
took  place  in  that  year  at  the  hands  of  Mr.  Spencer 
Wells,  I  say  it  may  as  well  be  claimed  for  him  that  he 
revived  the  moon.  To  Dr.  Charles  Clay  is  due  the 
credit  of  having  established  ovariotomy  in  England,  and 
carried  it  through  its  early  struggles.  His  practice  was 
a  mistaken  one  in  the  use  of  the  long  ligatures,  but  its 
results  were  certainly  no  worse  than  those  obtained  by 
the  clamp.  Dr.  Clay,  unfortunately,  did  not  know  of  the 
results  obtained  by  Nathan  Smith  from  the  use  of  the 
short  ligature.  Had  he  done  so,  abdominal  surgery 
would  have  been  half  a  century  in  advance  of  its  present 
position,  for  then  it  would  have  been  impossible  for  the 
clamp  ever  to  have  made  its  appearance.  Baker  Brown 
re-introduced  Nathan  Smith's  principle,  and  Keith  has 
brought  it  to  perfection." 

The  Therapeutic  Effect  of  Prayer. — Dr.  L.  A. 
Wohlfarth,.in  the  Medical  Index^  reports  a  very  excellent 
result  from  prayer.  His  patient  was  a  woman  who,  two 
weeks  before,  had  been  delivered  of  a  child.  She  suf- 
fered from  great  mental  excitement  and  a  delusion  that 
she  must  die.  He  says  :  **  Acting  on  a  hypothesis  of 
psychological  therapeutics,  and  thinking  that  a  '  prayer ' 
offered  by  an  old,  respected,  and  much  desired  friend 
like  Mr.  Davis,  possibly  might  have  a  salutary  influence 
on  a  diseased  mind  to  dispel  the  ^  notion  of  dying,'  ac- 
companied by  Mr.  Moses,  I  called  on  Mr.  Davis  and 
requested  him  to  see  Mrs.  Thomas,  and  '  if  occasion 
should  offer,'  to  give  prayer,  but  to  formulate  the  lan- 
guage of  his  prayer  in  a  hopeful  and  inspiring  tone.  The 
old  gentleman  consented,  and  at  my  next  visit  I  found 
the  result  of  his  *  prayer  '  almost  miraculous.  The  *  no- 
tion of  dying '  had  nearly  left  my  patient.;  she  was  doing 
well  The  puerperal  mania  was  cured,  but  the  patient 
subsequently  died  from  hypostatic  pneumonia." 

Fewer  Medical  Students. — Reports  seem  to  show 
that  in  most  of  the  larger  medical  colleges  the  number 
of  students  this  year  is  somewhat  below  the  average.  If 
this  is  a  fact,  it  is  to  be  attributed  to  the  hard  times,  and 
to  the  very  universal  opinion  among  non-teaching  doctors 
that  there  have  been  too  many  students  in  the  past. 

Suicide  of  a  Physician  accused  of  Malpractice. 
— Vienna  medical  circles  are  excited  over  the  suicide 
of  a  Dr.  Spitzer,  who  was  charged  with  maltreatment  of 
a  case,  his  applications  to  an  injured  limb  having  ap. 
parently  been  the  cause  of  acute  gangrene.  During  the 
course  of  his  trial,  Dr.  Spitzer  disappeared,  and  his  body 
was  subsequently  found  in  the  Danube. 


Renal  Calculus  Caught  in  the  Urethra,  Reten- 
tion OF  Urine,  Convulsions,  Urethrotomy,  Cure. — 
Dr.  E.  D.  Coonley,  of  Mariner's  Harbor,  Staten  Island, 
was  called  to  see  a  boy,  aged  twelve,  suffering  from  severe 
pain  in  the  side.  An  opiate  was  given  and  relief  followed. 
Three  days  later  the  doctor  was  called  again  and  found 
the  boy  in  convulsions  and  apparently  dying.  He  had 
not  passed  water  for  two  days.  An  obstruction  was 
found  in  the  urethra  near  the  junction  of  the  scrotum  and 
perineum.  External  urethrotomy  was  performed,  and  an 
ovoid  uric  acid  calculus,  weighing  13  grains,  was  extracted. 
The  boy  recovered. 


7H 


THE  MEDICAL   RECORD. 


[December  27, 188^ 


^epoxts  of  ^ocUtUs. 


NEW  YORK  ACADEMY  OF  MEDICINE. 

Seated  Meetings  December  18,  1884. 

FoRDYCE  Barker,  M.D.,  LL.D.,  President,  in  the 
Chair. 

The  President  appointed  Drs.  H.  D.  Nicoll  aiid  S.  F- 
Morris,  who,  with  the  Assistant  Secretary,  shall  cunstitute 
a  Board  of  Inspectors  at  the  next  annual  meeting,  to  be 
held  January  15,  1885,  the  first  Thursday  in  the  month 
falling  on  the  first  day  of  January. 

The  President  then  called  Dr.  R.  F.  Weir,  First  Vice- 
President,  to  the  Chair. 

Dr.  Weir  announced  as*the  next  order  of  business 

REPORT^ OF  THE    COMMITTEE     ON    ETHICS,    ON    CHARGES 
PREFERRED    AGAINST  A    FELLOW. 

Dr.  Ellsworth  Eliot  remarked  that  it  had  been 
customary,  and  moved  that  the  hearing  of  the  report  be 
postponed  until  after  the  scientific  business  of  the  even- 
ing.    Lost. 

Dr.  W.  T.  White  said  it  had  been  customary,  and 
moved  that  the  Academy  go  into  executive  session,  which 
would  exclude  the  representfitives  of  the  daily  press  that 
had  no  right  to  the  proceedings,  and  also  remove  med- 
ical students  and  others  who  had  no  right  to  participate. 

Dr.  E.  D.  Hudson,  Jr.,  opposed  the  motion  on  the 
ground  that  one  side  of  the  question,  namely,  that  pre- 
sented by  the  accusers,  had  already  in  some  mysterious 
way,  perhaps  not  so  mysterious  after  all,  found  publication 
in  some  of  the  daily  papers,  and  now  all  the  proceedings 
should  be  open  and  above  board  The  Academy  should 
not  countenance  any  *•  star-chamber"  inquiry. 

Dr.  F^  V.  White  favored  an  executive  session  because 
it  was  improper  for  the  Academy  to  wash  its  "  dirty  linen" 
in  public,  and  besides  it  was  contrary  to  the  spirit  of  the 
by-laws  and  constitution  of  the  organization. 

The  motion  was  put  and  lost. 

Dr.  Andrew  H.  Smith,  Chairman  of  the  Committee 
on  Ethics,  then  read  the  unanimous  report  of  the  Com- 
mittee, reached  as  the  result  of  repeated  sittings  con- 
ducted with  all  possible  precautions  at  every  step  of  the 
entire  investigation.  It  was  that  the  charges  against  a 
Fellow,  of  having  claimed  a  degree  of  M.D.,  which  he 
never  possessed,  and  of  having  falsely  signed  his  name 
upon  the  signature  book  of  the  New  York  Academy  of 
Medicine,  also  upon  the  register  of  physicians  at  the 
office  of  the  Clerk  of  the  County  of  New  York,  in  1880, 
and  at  divers  times  and  places,  were  unsustained,  the 
Committee  finding  them  to  be  without  foundation  and  ab- 
solutely untrue. 

The  report  was  signed  by  the  Chairman  and  the  other 
members  of  the  Committee,  Drs.  V.  P.  Gibney,  C.  A. 
Leale,  H.  E.  Crampton,  and  C.  D.  Varley,  Secretary. 

The  report  was  received  with  immense  applause,  and 
was  accepted  and  adopted  without  a  dissenting  voice. 

Dr.  C.  R.  Agnew  moved  that  the  report  of  the  Com- 
mittee of  Ethics  be  spread  in  full  upon  the  minutes  of 
the  Academy.     Carried. 

Dr.  J.  W.  Howe  remarked  that  it  appeared  from  the 
report  of  the  Committee  that  the  signature  of  the  accused 
in  the  book  of  signatures  of  the  Academy  had  been  tam- 
pered with,  probably  falsified,  and  he  therefore  moved  that 
a  Committee  of  Three  be  appointed  by  the  Chair  to  inves- 
tigate with  reference  to  the  source  of  the  mutilation  of 
the  records,  and  to  report  to  the  Academy.     Carded. 

The  Vice-President  announced  that  he  would  ap- 
point the  Committee  subsequently. 

Dr.  John  C.  Peters  directed  attention  to  the  point 
that  it  was  the  duty  of  the  accusers  to  have  complied 
with  the  by-laws,  first  notified  the  accused  that  the  charges 
were  to  be  made,  and  then  called  for  a  court  medicale^ 
in  which  efforts  could  be  made  to  adjust  the  differences 
by  arbitration  ;  that  only  when  efforts  had  failed  in  this 


direction  to  accomplish  the  desired  end,  were  the  accus- 
ers justified  in  t)ringing  the  subject  before  the  Academy. 
He  therefore  moved  a  vote  of  censure  for  the  accusers 
because  they  did  not  observe  the  rules  of  professional 
courtesy  laid  down  by  the  State  Medical  Society  and  tbc 
by-laws  of  the  Academy. 

Dr.  Roosa  moved  to  amend  by  asking  the  Fellows 
who  signed  the  charges  to  send  in  their  resignations. 

Dr.  Peters  accepted  the  amendment 

Dr.  Jacobi  was  willing  to  vote  to  censure  the  Fellows 
who  signed  the  charges,  but  was  not  ready  to  vote  for 
Dr.  Roosa's  amendment,  which,  if  carried,  would  be 
practically  an  expulsion. 

Dr.  Wylie  thought  it  perhaps  not  exactly  fair  to  ask 
all  the  Fellows  who  signed  the  charges  to  resign. 

Dr.  Poolev  moved  as  an  amendment  that  the  Fellows 
who  signed  the  charges  be  expelled. 

Dr.  Henry  supported  Dr.  Pooley's  amendment  with 
a  vigorous  speech,  in  which  he  claimed  that  not  a  sod- 
tilla  of  testimony  had  been  adduced  by  the  accusers 
which  would  be  admitted  as  evidence  in  a  court  of  law, 
and  that  every  one,  from  the  giant  of  the  outrage  to  the 
babies  who  signed  with  him,  deserved  expulsion.  There 
was  not  a  club  or  association  of  gentlemen  anywhere  in 
the  world  that  would  not  expel  any  member  for  the 
same  offence,  and  without  another  word  being  said  io 
their  condemnation  other  than  that  which  nad  appeared 
in  the  most  admirable  report  of  the  Committee. 

Dr.  J.  C.  Dalton  thought  that  after  hearing  the  ohd. 
plete,  thorough,  and  exhaustive  report  of  the  Committee 
on  Ethics,  the  Fellows  should  be  satisfied  that  the  ques- 
tion had  been  set  at  rest.  The  report  was  exactly  what 
the  Academy  wanted,  and  he  felt  that  the  Fellows  should 
be  content  to  adopt  the  report,  because  they  could  net 
have  anything  that  was  better,  and  it  was  very  easy  to 
have  something  worse.  He  therefore  moved  to  lay  upon 
the  table  all  the  motions  and  amendments  offered  after 
the  unanimous  adoption  of  the  report. 

The  President  was  allowed  to  say  that  he  most 
heartily  approved  of  the  sentiments  expressed  by  Dr. 
Dalton;  that  he  felt  satisfied  with  the  action  which tiie 
Academy  had  taken,  and  that  he  thought  it  would  bcm- 
jurious  to  resort  to  any  extreme  measures. 

The  motion  and  the  amendments  were  then  withdrawn, 
and  the  Academy  proceeded  widi  the  regular  order  of 
business. 

The  President,  on  resuming  the  chair,  said :  **  Heie 
endeth  the  second  lesson.  The  Academy  will  not 
resume  its  scientific  work,  which  has  been  continued  har- 
moniously for  thirteen  months,  until  interrupted  by  tte 
supreme  effort  to  elevate  the  character  of  the  medial 
profession." 

At  the  request  of  the  author,  the  reading  of  Dr.  Gis^ 
par  Griswold's  paper  on  "  Electricity  as  a  Cardiac  aixl, 
Respiratory  Stimulant,"  was  postponed  until  some  fiitare 
meeting. 

Dr.  a.  M.  Jacobus  introduced  the  following  rcsota- 
tions,  with  a  preamble,  which  were  adopted. 

medical  education  and  a  state  board  of  EXAMnfBi 

Resolved,  That  the  Committee  on  Medical  EducaW 
of  this  Academy  be  instructed  to  inquire  into  the  quoaij 
whether  it  be  advisable  to  have  a  "State  Board  ot&- 
aminers,"  and  also  as  to  the  import  of  any  proposed  lis 
and  such  other  matters  pertaining  to  the  general  subject 
as  to. them  shall  appear  pertinent. 

Resolved,  That  the  Committee  be  directed  to  report  at 
the  stated  meeting  of  the  Academy,  to  be  held  JanBaj. 
i5i  1885,  and  that  such  report  be  made  one  of  the  special 
orders  for  that  meeting. 

The  Secretary,  Dr.  Katzenbach,  read  a  letter  I^ 
ceived  from  Dr.  S.  T.  Hubbard,  in  which  he  withdrcf 
his  name  from  the  list  of  nominations  for  President 

The  resignation  of  Dr.  Horatio  Gomez  was  aacpte^ 
and  the  time  for  Dr.  Woolsey  Johnson  to  sign  ihebp 
laws  extended,  after  which  the  Academy  adjourned. 


December  27,  1884.] 


THE  MEDICAL  RECORD 


715 


MEDICAL    SOCIETY    OF    THE    COUNTY    OF 
NEW   YORK. 

Stated  Meetings  December  22,  1884. 

Daniel  Lewis,  M.D.,  President,  in  the  Chair. 

THE   physiological  AND  THERAPEUTIC  EFFECfS  OF  THE 
COCA   LEAF  AND   ITS   ALKALOID. 

Dr.  William  Oliver  Moore  read  a  paper  on  the  above 
subject  in  which  he  reviewed  the  literature  of  the  drug, 
and  gave  an  account  of  the  various  uses  which  have  been 
made  of  it.  Especial  attention  was  directed  to  its  gen- 
eral tonic  eflfects,  its  use  in  the  treatment  of  affections  of 
the  larynx,  pharynx,  and  tonsils,  and  in  the  treatment  of  the 
opium  habit,  where  it  had  been  reported  to  be  of  service. 
Attention  was  then  directed  to  the  use  of  the  alkaloid 
cocaine,  its  first  effect  being  to  produce  anaemia,  and  sec- 
ondy  anaesthesia  of  the  parts  to  which  it  is  applied,  the 
effect  being  especially  marked  on  mucous  membranes. 
Instillations  into  the  eye  of  the  affected  side  had  proved 
very  serviceable  in  cases  of  hemicrania,  and  Dr.  Moore 
suggested  that  the  alkaloid  might  afford  relief  in  sea- 
sickness. In  operations  involving  the  skin  the  effect  of 
the  alkaloid  was  very  much  enhanced  by  first  removing 
the  epidermis. 

The  discussion  was  opened  by  Dr.  Roosa,  who  thought 
that  the  enthusiasm  of  the  ophthalmologists  might  be  ex- 
cused, even  in  the  glare  of  the  luminous  remark  in  The 
Medical  Record  concerning  "the  lonesome  man," 
since  it  had  been  established  beyond  doubt  that  in  a  very 
large  number  of  operations  heretofore  requiring  the  use 
of  general  anaesthetics,  the  smothering  cone,  and  not  only 
that  but,  what  was  more  important,  the  pain,  had  been 
done  away  with,  a  triumph  which  no  one  was  better 
qualified  to  appreciate  than  the  editor  of  The  Medical 
Record  himself. 

The  only  disappointment  which  Dr.  Roosa  had  to 
record  was  concerning  the  value  of  cocaine  in  otology, 
where  he  was  not  as  yet  at  all  satisfied  as  to  its  true 
place  as  a  therapeutic  agent.  It  should  be  remembered, 
however,  that  to  determine  the  true  therapeutical  effect  of 
drugs  was  a  much  more  difficult  problem  to  solve,  than 
to  merely  learn  what  the  effects  were  which  these  drugs 
produced  when  applied  locally. 

Dr.  Willlam  M.  Polk,  with  reference  to  gynecolog- 
ical practice,  had  found  that  the  best  method  of  using 
cocaine  was  by  hypodermic  injection.  For  example,  in 
several  cases  of  laceration  of  the  cervix,  he  had  been  able 
to  operate  without  pain  to  the  patient,  by  injecting  four 
minims  of  a  four  per  cent,  water  solution  into  the  tissue 
of  the  cervix  on  each  side  shortly  before  beginning  with 
the  knife.  In  certain  patients  belonging  to  this  class, 
therefore,  he  believed  it  had  a  limited  application. 

In  the  removal  of  the  wire  sutures  after  ordinary  peri- 
neorrhaphy, he  had  found  it  especially  serviceable.  He 
had  also  used  it  successfully  before  applying  the  actual 
cautery  to  carcinoma  of  the  cervix  extending  to  the 
vagina,  and  also  before  using  caustics  in  the  treatment  of 
chancre  and  chancroid. 

With  the  assistance  of  Dr.  Le  Fevre,  of  Bellevue  Hos- 
pital, the  hypodermic  use  of  cocaine  behind  and  in  front 
of  the  cervix  uteri,  had  mollified  the  severity  of  labor 
pains  very  markedly. 

A  curious  fact  sdso  obtained  in  those  cases,  namely, 
there  was  anaesthesia  of  the  cornea. 

In  one  case  he  had  performed  hepatotomy,  for  hydatid 
cyst  and  abscess,  with  the  aid  of  cocaine  applied  locally. 
The  local  ^anaesthetic  was  used,  because  of  the  bad 
general  condition  of  the  patient,  which  contra-indicated 
the  use  of  either  ether  or  chloroform. 

Dr.  Knapp  had  noticed  that  dilatation  of  the  pupil, 
ad  maximum^  was  not  produced  by  cocaine. 

Dr.  Pooley  thought  the  use  must  be  abandoned  in  a 
certain  number  of  cases  occurring  in  children,  because  of 
the  fright  and  agitation  which  occurred  without  the  use 
of  a  general  anaesthetic.     He  also  regarded  the  method 


of  injecting  the  orbital  tissues  as  a  procedure  liable  to  be 
attended  with  disastrous  consequences,  hence  should  be 
adopted  only  with  the  greatest  care. 

In  one  case  he  had  noticed  marked  toxic  effect  of  the 
drug  ten  minutes  after  a  single  instillation  of  a  four  per 
cent,  solution  into  the  eye.  There  was  pronounced  ver- 
tigo, and  the  pupil  in  that  case  was  apparently  dilated 
ad  maximum.  He  had  relieved  the  patient  in  one  case 
of  hemicrania,  by  a  single  instillation  into  the  eye  upon 
the  affected  side. 

Dr.  Hope  spoke  of  the  efficacy  of  cocaine  as  a  local 
anaesthetic  in  a  case  of  laryngeal  growth. 

Dr.  F.  a.  Castle  referred  to  points  in  the  literature 
of  the  subject  and  also  in  the  modes  of  obtaining  the 
alkaloid.  He  also  directed  attention  to  the  local  anaes- 
thetic effects  produced  by  certain  other  drugs,  as  can- 
nabis indica,  kola-nut,  etc.,  with  which  experiments  were 
being  made. 

Practically,  he  had  used  cocaine  in  a  case  of  urethral 
stricture,  which  he  was  able  to  dilate  without  producing 
very  much  pain,  and  also  in  a  case  of  sensitive  nipples^ 
with  considerable  benefit. 

Dr.  W.  F.  Mittendorf  thought  that  the  peculiar  ef- 
fect of  cocaine  was  produced  by  its  action  on  the  capil- 
laries, first  causing  anpemia  about  the  terminal  nerve-fibres, 
and  that  this  anaemia  was  the  principal  factor  in  develop- 
ing the  local  anaesthesia. 

With  reference  to  the  mydriatic  effect,  he  believed  it 
to  be  due  to  the  action  of  the  alkaloid  upon  the  sympa- 
thetic nerve-fibres.  He  did  not  agree  with  Dr.  Pooley, 
and  thought  that  the  best  effects  of  the  drug  were  ob- 
tained in  the  treatment  of  children.  The  pressure  of  the 
eye-speculum  sometimes  complained  of,  he  had  been  able 
to  overcome  by  the  use  of  his  own  instrument. 

Dr.  J.  Leonard  Corning  spoke  of  the  effect  pro- 
duced by  coca  in  the  central  nervous  system,  and  had 
found  it  especially  serviceable  in  the  treatment  of  anae- 
mic, hysterical,  neurasthenic  females,  the  spinal  concus- 
sion of  Erichsen,  etc. 

Dr.  William  H.  Thomson,  from  a  tolerably  large  ex- 
perience in  both  hospital  and  private  practice,  had 
reached  the  conclusion  that  the  value  of  coca  as  a  medi- 
cine was  about  equal  to  that  of  boneset ;  not  quite  so 
good  as  fresh  boneset.  This,  however,  did  not  at  all 
militate  against  its  value  as  a  local  anaesthetic. 

He  had  used  cocaine  as  a  local  application  in  the 
treatment  of  pruritus  vulvae,  with  exceedingly  satisfactory 
results. 

Dr.  Sell  spoke  of  the  use  of  avena  sativa  in  the  treat- 
ment of  the  opium  habit. 

The  Secretary  read  the  following  communication 
from  Dr.  A.  P.  Meylert,  which  had  a  bearing  upon  the 
question  of  the  therapeutical  value  of  coca,  and  also  of 
the  value  of  the  coca  and  its  alkaloid,  in  the  treatment  of 
the  opium  habit : 

"  So  much  has  been  written  about  the  value  of  this 
drug  in  cases  of  opium  habituation  that  I  have  many 
times  endeavored  to  use  the  various  preparations  of 
coca  leaf  in  this  disorder,  but  little  advantage  has  re- 
sulted therefrom.  Alcoholic  preparations  were  contra- 
indicated  in  many  cases  complicated  with  chronic  alco- 
holism, and  in  my  judgment  were  hazardous  in  other 
cases  from  the  tendency  in  habit  cases  to  inebriety.  The 
fluid  extract  of  coca  in  small  doses  was  without  apparent 
effect,  and  in  large  doses  was  nauseating.  The  solid  ex- 
tract in  pill  form  seemed  almost  inert. 

*'  It  was  therefore  with  gladness  that  I  read  of  the  new 
anaesthetic — the  cocaine  alkaloid — and  hastened  to  give 
it  a  trial  as  a  substitute  for  morphia  in  habit  cases. 

'<  I  have  used  it  both  by  the  mouth  and  subcutaneously, 
using  a  solution  of  sixteen  grains  in  the  fluid  ounce,  being 
one  grain  in  thirty  minims. 

*'  I  will  give  the  general  results  briefly  so  far  as  ob- 
served, reserving  details  for  the  future. 

'*  Administered  alone  in  doses  of  five  to  ten  minims, 
there  was  no  effect  which  I  could  fairly  attribute  to  the 


7i6 


THE   MEDICAL   RECORD. 


[December  27,  1884. 


drug.  In  doses  of  fifteen  to  twenty  minims,  equal  to  one- 
half  to  two-thirds  of  a  grain,  there  was  little  if  any  relief 
from  pain  or  from  the  hyperesthesia  and  general  uneasi- 
ness of  the  patient,  but  the  face  became  pallid,  the  pulse 
small,  and  a  sense  of  exhaustion  followed.  From  this, 
however,  the  patient  quickly  rallied  on  administering  the 
usual  dose  of  morphia. 

"  When  the  alkaloid  was  administered  subcutaneously 
with  2l  solution  of  morphia,  the  only  perceptible  effect  of 
the  cocaine  was  to  enhance  somewhat  the  exhilarating 
effect  of  the  morphia.  It  did  not,  however,  prolong  the 
period  of  quiescence  induced  by  the  dose  of  morphia, 
nor  could  a  less  quantity  of  the  narcotic  satisfy  the 
patient. 

**  On  the  day  subsequent  to  the  administration  of  the 
cocaine,  however,  a  larger  reduction  of  the  morphia  was 
easily  tolerated. 

"The  above  doses  are  doubtless  large,  exdept  for  those 
taking  five  to  thirty  grains  of  morphia  daily. 

"I  am  therefore  pursuing  these  investigations  with 
great  interest,  and  hope  to  hear  the  experience  of  other 
observers  in  this  field." 

The  discussion  was  closed  by  Dr.  Moore,  after  which 
the  Society  adjourned. 

^jexa  %usXxumtnXs. 


FLEXED  SPLINTS. 

Dr.  W.  D.  Kearns,  of  Pittsburg,  Pa.,  introduces,  in  a 
paper  read  by  him  before  the  Allegheny  County  Medical 
Society,  somewhat  of  a  novelty  in  the  form  of  "flexed 
splints."  In  presenting  them  to  the  profession,  he  has 
been  encouraged  and  sustained  not  only  by  personal 
tests,  but  also  by  the  approval  of  recognized  authority, 
in  regard  to  the  soundness  and  feasibility  of  the  princi- 
ples evolved,  especially  referring  to  Colles'  fracture. 

Dr.  Kearns  reviews  the  several  varieties  of  splints 
usually  employed,  condemning  some,  and  calling  atten- 
tion to  the  incompetency  of  the  straight  padded  splint  to 
secure  the  necessary  angles  of  flexion  of  the  wrist-joint 
and  metacarpo-phsilangeal  articulation ;  at  the  same 
time  suggesting  the  congruity  of  a  flexed  splint.  He 
considers  the  latter  less  complicated  than  the  padded 
straight  splint^  inasmuch  as  the  bend  of  the  \vTist  and 
hand  is  at  once  pennanently  fixed.  Whether,  he  ad- 
vises, the  fracture  of  the  radius  is  transverse,  oblique, 
more  or  less  longitudinal,  or  more  or  less  comminuted, 
the  conditions  governing  the  form  of  the  retaining  splints, 
after  complete  reduction,  are  equally  exacting,  and  are 
best  subserved  by  flexed  splints,  through  their  greater  ef- 
ficiency in  forestalling  the  formidable  impairment  of  the 
functions  of  flexion,  extension,  pronation,  and  supination. 

He  also  directs  attention,  comparatively,  to  fractures 
of  the  radius  and  ulna,  and  the  necessity,  after  complete 
reduction,  of  maintaining  relaxation  of  the  several  mus- 
cular tendons,  fasciae,  and  ligaments,  and  that  the  con- 
tinued maintenance  of  this  relaxation  is  also  of  para- 
mount importance  in  connection  with  fractures  of  the 
wrist ;  and  it  is  claimed  that  flexed  splints  will  admit 
and  secure  correlative  relaxation.  Flexed  splints,  he 
finds,  propose  a  ready,  comfortable,  and  efficient  main- 
tenance of  all  appreciable  required  muscular  relaxation 
of  the  extensors  and  flexors  to  their  insertions  along  the 
phalanges,  and  of  the  muscles  and  fasciae  of  the  hand 
and  thumb  ;  and,  also,  may  claim  a  great  advantage  in 
securing  the  more  early,  free,  and  full  use  of  the  hand. 

The  insertion  of  thin,  narrow,  interosseous  pads  are 
employed,  and  materially  control  the  displacing  influ- 
ences of  the  pronator  quadratus  and  the  supinator  longus. 
Interosseous  pads,  he  finds,  will  also  fully  compensate 
the  pistol-shaped  splint  of  Ndaton,  in  preventing  the  ap- 
proach of  the  fragments  to  the  ulna.  Short  splints,  or  a 
short  palmar  splint  and  a  long,  straight  dorsal  splint,  he 
considers  inadequate  to  immobilize  the  proximal  joint. 


An  "immediate"  bandage,  if  loosely  and  intelligently 
applied,  will  advantageously  subserve  its  purpose  in  pre- 
venting  muscular  contraction. 

He  observes  that  the  angle  of  flexion  of  the  dorsal 
splint  (Fig.  i)  is  made  studiously  sharp  at  the  wrist, 
carefully  evading  pressure  on  the  carpal  bones.  This 
angle  should  also  be  of  degree  sufficient  (about  122'' 
Fig.  i),  by  the  backward  bend  of  the  hand,  to  se- 
cure complete  relaxation  of  the  posterior  muscular  ten- 
dons; while  the  anterior  relaxation  is  effected  by  the 
partial  closing  of  the  hand.  The  splints  admit  a  slight 
drooping  of  the  hand  (the  natural  curve  of  uncontrolled 
muscular  action). 


The  accompanying  woodcut  traces  the  anterior  edge 
of  the  palmar  splint  (Fig.  2)  as  a  continuous  line  fully 
over  the  muscular  prominence  of  the  three  flexors  of  the 
palmar  surface  of  the  thumb,  preserving  their  full  uncon- 
straint,  whence  it  inclines  underneath  the  thumb  along 
the  index  finger,  restoring  the  width  of  the  splint  to  that 
of  the  hand.  Wooden  splints,  which  can  now  be  readily 
sawn,  he  considers  practically  the  best.  They  can, 
however,  be  constructed  of  sheet  zinc,  which,  judging 
from  the  specimens  sent  us,  would  also  serve  an  excel- 
lent purpose. 


Official  List  of  Changes  in  the  Stations  and  Duties  of  Officers 
serving  in  the  Medical  Department^  United  States  Army^ 
from  December  7  to  December  20,  1884. 

'"4HAMMOND,  John  F.,  Colonel  and  Surgeon.  Retired 
from  active  service,  by  operation  of  law,  on  December  7, 
1884,  under  provision  of  Act  of  Congress  approved  June 
30,  1882.     S.  O.  287,  A.  G.  O.,  December  8,  1884. 

McKee,  J.  C,  Major  and  Surgeon.  Leave  of  absence 
still  further  extended  one  month.  S.  O.  288,  A.  G.  0., 
December  9,  1884. 

Porter,  Joseph  Y.,  Captain  and  Assisuut  Surgeon. 
Sick  leave  of  absence  extended  four  months,  on  surgeon's 
certificate  of  disability.  S.  O.  286,  A.  G.  O.,  December 
6,  1884. 

Kane,  John  J.,  Captain  and  Assistant  Surgeon.  From 
Department  of  the  East  to  VVillet's  Point,  New  York.  S, 
O.  286,  A.  G.  O.,  December  6,   1884. 

Banister,  J.  M.,  Captain  and  Assistant  Surgeon  (Fort 
Adams,  R.  1.).  Granted  one  month's  leave  of  absence,  on 
surgeon's  certificate  of  disability.  S.  O.  251,  Department 
of  tihe  East,  December  9,  1884. 

Gray,  Charles  C,  Major  (retired).  Died  at  Geneva, 
N.  Y.,  November  22,  1884,  instead  of  November  26th,  as 
heretofore  announced.  Circular  Orders,  A.  G.  O.,  De- 
cember 8, 1884. 

Lauderdale,  John  V.,  Captain  and  Assistant  Surgeon, 
Fort  Sully,  D.  T.  Granted  leave  of  absence  for  one 
month,  to  take  effect  about  December  20,  1884.  S.  0. 
146,  Department  of  Dakota,  December  9,  1884. 


December  27,  1884.] 


THE  MEDICAL  RECORD. 


717 


CoMEGYS,  £.  T.,  Captain  and  Assistant  Surgeon. 
Granted  leave  of  absence  for  one  month.  S.  O.  234, 
Department  of  the  Missouri,  December  8,  1884. 

PiLCHER,  J.  E.,  First  Lieutenant  and  Assistant  Surgeon. 
Ordered  to  Fort  Custer,  M.  T.,  for  duty.  Order  as- 
signing him  to  duty  at  Fort  A.  Lincoln,  D,  T.,  amended, 
S.  0.  145,  Department  of  Dakota,  December  8,  1884. 


Official  List  of  Changes  in  the  Medical  Corps  of  the  U.  S, 
Navy,  during  the  week  ending  December  13, 1884. 

Craig,  T.  C,  Passed  Assistant  Surgeon.  Detached 
from  Alliance  and  placed  on  waiting  orders.  December 
6,  1884. 

Curtis,  L.  W.,  Assistant  Surgeon.  To  the  Naval 
Hospital,  Chelsea.     December  9,  1884. 

Gaines,  J.  H.,  Passed  Assistant  Surgeon.  Present 
duty  continued. 

Green,  E.  H.,  Passed  Assistant  Surgeon.  Special 
duty  at  Museum  of  Hygiene,  Washington.  December 
II,  1884. 

Meurray,  J.  M.,  Passed  Assistant  Surgeon.  Detached 
from  Naval  Hospital,  Chelsea,  to  the  Flagship  Hartford. 
December  9,  1884. 

Woolverton,  T.,  Surgeon.  To  the  Shenandoah.  De- 
cember 6,  1884. 


([^OXXitSVOXiiitXitt. 


CARD  FROM  DR.  FORDYCE  BARKER. 

To  THS  Editor  or  Thb  Medical  Rxcord. 

Sir  :  Will  you  allow  me  a  small  space  to  express  the 
deep  feeling  which  has  touched  my  heart  by  the  recep- 
tion of  a  great  number  of  letters  since*last  Friday  morn- 
ing? 

As  from  members  of  the  medical  profession  of  this  city 
and  Brooklyn,  I  have  already  received  more  than  two 
hundred,  and  very  many  letters  and  telegrams  from  other 
places,  it  is  quite  impossible  for  me  to  send  an  acknowl- 
edgment to  each  writer,  I  must  pray  my  friends  to  ac- 
cept my  thanks  through  the  medium  of  your  journal. 

FoRDYCB  Barker. 

34  East  TmirTY-BiGHTM  Stkrbt, 
Monday  evenings  Deoember  aa,  2884. 


piedicaX  Items. 


Contagious  Diskasss — ^Wsskly  Statsmsnt. — Re- 
port of  cases  and  deaths  from  contagious  diseases  re- 
ported to  the  Sanitary  Bureau,  Health  Department,  for 
the  week  ending  December  20,  1884 : 


Week  Ending 


Cases. 

December  13,  1884. 
December  20,  1884. 


Deaths. 
December  13,  1884. 
December  20,  1884 . 


70 
106 


h 


I 


I 


118 
130 


The  Practice  of  Medicine  in  Russia. — A  recent 
number  of  the  Aerztliches  Vereinsblatt  contains  an 
interesting  article  on  "  Medicine  in  Russia,"  written  by  a 
German  physician  practising  in  that  country.  The  num- 
ber of  physicians  in  Russia,  according  to  the  official  sta- 
tistics for  1883,  is  15,231.  Most  of  these  are  collected 
in  the  cities,  while  the  country  is  so  poorly  supplied  that 
there  are  districts  as  large  as  Saxony  or  Bavaria  where 
there  is  but  one  physician.     There  are  medical  faculties 


in  Kief,  Kazan,  Charkov,  Moscow,  Warsaw,  Helsingfors, 
and  Dorpat,  the  first  five  of  which  give  instruction  in  the 
^  Russian  language,  while  at  Helsingfors  Swedish  is  spoken, 
and  at  Dorpat  German.  There  is,  besides,  an  army 
medical  school.  In  the  Russian  schools  there  is  a  five- 
years'  graded  course  with  yearly  examinations.  At  the 
end  of  this  course  an  examination  must  be. passed  for  the 
title  of  physician,  after  which,  if  it  is  so  desired,  the  can- 
didate may  pass  on  to  the  doctorate  examination.  In 
Dorpat  there  is  no  graded  course,  and  but  two  examina- 
tions are  held.  The  first,  called  the  examen  phylosophi- 
cuniy  is  passed  usually  after  two  or  three  years*  study, 
and  embraces  the  subjects  of  chemistry,  physics,  botany, 
mineralogy,  zoology,  anatomy,  physiology,  general  pa- 
thology, and  dietetics.  If  a  student  allows  four  years  to 
elapse  after  his  philosophical  examination  before  coming 
up  for  the  rigorosuniy  he  is  obliged  to  pass  the  former 
over  again.  It  sometimes  happens  that  students  who 
become  interested  in  some  special  subject  pass  this  ex- 
amination three  or  four  times  before  coming  up  for  their 
final.  At  the  final  examination,  the  examen  rigorosum, 
the  student  chooses  whether  he  will  try  for  the  title  of  phy 
sician  or  of  doctor.  In  order  to  obtain  the  latter  degree 
a  more  exact  knowledge  of  theoretical  subjects  is  neces- 
sary, and  in  addition  the  candidate  must  write  two  theses, 
on  given  subjects,  in  Latin.  If  he  is  thus  far  successful 
he  must  attend  and  take  part  in  a  dissertation.  A  doc- 
tor ranks  as  eighth  in  the  classes  defined  by  the  State, 
while  a  physician  is  one  step  farther  down  the  scale. 
No  one  can  receive  an  appointment  as  head  physician 
in  a  hospital  or  become  a  "  privat-docent "  unless  he 
possess  a  degree  of  M.D.  Russia  has  a  paternal  govern- 
ment, and  her  medical  sons  are  not  neglected,  but  are 
placed  under  the  care  of  the  Minister  of  the  Interior. 
The  business  of  the  medical  division  of  the  Department 
of  the  Interior  is  defined  to  be  to  keep  an  eye  "  on  the 
industry  and  scientific  ability  of  the  physicians,  and  to  re- 
port thereon  yearly."  It  also  takes  them  under  its  pro- 
tection when  they  are  subject  to  unjust  attacks.  It  has 
further  to  see  that  the  sick  are  treated  only  by  physi- 
cians of  proved  skill,  and  must  warn  the  people  against 
the  dangers  of  employing  charlatans.  One  article  of 
the  medical  law  provides  for  the  punishment  of  those 
who  employ  quacks.  The  law  also  gives  the  depart- 
ment authority  to  transfer  physicians  from  one  place  to 
another  as  occasion  may  require  :  thus  in  case  of  an  epi- 
demic in  a  place  where  physicians  are  scarce,  the  Minis- 
ter of  the  Interior  can  send  others  from  places  where 
they  are  more  plentiful.  In  the  matter  of  fees  the  law 
is  also  explicit,  and  as  the  law  was  framed  in  1 789  and 
has  never  been  altered,  it  may  readily  be  understood 
that  the  lawful  fees  are  not  exorbitant.  For  a  visit  in  the 
city  a  doctor's  legal  charge  is  30  copecs  (24  cents)  if  he 
gives  a  prescription,  and  15  copecs  (12  cents)  if  he 
writes  no  prescription.  For  a  visit  outside  of  the  city 
he  is  allowed  to  ask  60  copecs  (nearly  half  a  dollar). 
A  consultation  is  held  to  be  worth  $1.20.  A  physi- 
cian's fee  is  set  down  at  12  cents  with  or  without  a  pre- 
scription. For  applying  a  blister  or  giving  an  enema  he 
is  allowed  to  ask  the  enormous  sum  of  6  cents,  and  a 
venesection  is  held  to  be  of  equal  value.  Wet  cups  are 
to  be  applied  at  the  rate  of  2  J  cents  each.  An  obstetri- 
cian who  has  assisted  at  a  difficult  labor  may  demand 
$1.20  for  his  valuable  services.  These  charges  are  for 
attending  people  in  moderate  circumstances,  and  the 
rich  are  expected  to  pay  a  little  more.  This  is  the  law 
as  it  stands  upon  the  statute  book,  and  which  can  be  en- 
forced at  any  time,  but  practically,  of  course,  it  is  a  dead 
letter,  in  its  good  features  as  well  as  in  its  bad  ones. 
There  are  plenty  of  quacks  who  enjoy  a  lucrative  prac- 
tice, just  as  is  the  case  in  other  countries,  yet  occasion- 
ally one  of  these  gentry  comes  to  grief.  Not  long  ago  a 
most  elegant  gentleman  settled  in  St.  Petersburg,  pro- 
fessing to  be  an  ardent  disciple  of  Hahnemann,  and  by 
reason  of  his  fine  presence  and  engaging  manners  soon 
acquired  a  large  practice,  some  of  his  patients  being 


7i8 


THE  MEDICAL  RECORD. 


[December  27,  i8 


members  of  a  grand  ducal  family.  Before  long,  how- 
ever, it  was  discovered  that  his  sole  right  to  practise 
consisted  in  the  possession  of  a  diploma  from  the  Uni-  . 
versity  of  Philadelphia,  and  he  was  quickly  escorted  over 
the  border  and  earnestly  recommended  to  stay  there. 
The  number  of  homoeopathists  in  Russia  is  small,  yet 
those  who  are  there  are  divided  into  two  parties,  each  call- 
ing the  other  a  company  of  charlatans.  Their  experience 
with  hospitals  was  not  encouraging.  Three  years  ago 
they  started  a  hospital  for  the  treatment  of  diphtheria, 
which  for  some  time  had  no  inmates.  Finally,  on  the 
advice  of  a  homoeopathic  general,  a  soldier  sent  his 
child  there  for  treatment.  The  child  very  promptly 
died,  and  the  hospital  received  no  more  cases  of  diph- 
theria.  Russian  medical  societies  are  not  very  flourish- 
ing, owing,  the  writer  says,  to  an  every-man-for-hiniself 
spirit  that  exists  among  the  physicians  there.  The  old- 
est is  the  Society  of  Russian  Physicians,  founded  in  1833. 
The  members  of  this  society  are  intensely  national  in 
their  feelings,  as  was  evidenced  in  one  of  the  addresses  at 
their  semi-centennial  celebration,  when  the  speaker  con- 
gratulated his  hearers  that  at  last  Russian  medicine  had 
thrown  off  the  German  yoke.  This  feeling  was  also  ex- 
hibited in  an  order  recently  promulgated  by  the  Minister 
of  War,  to  the  effect  that  not  more  than  four  per  cent,  of 
the  army  surgeons  should  be  Jews.  There  are  five  other 
societies,  one  of  them  composed  chiefly  of  German  physi- 
cians, in  St.  Petersburg,  and  seventy-three  in  the  prov- 
inces. In  addition  there  are  several  mutual  aid  and  bene- 
fit societies  among  medical  men.  Considerable  progress 
has  been  made  in  the  last  decade  in  medical  journalism. 
The  leading  journal  is  the  Vratch  (the  Physician),  founded 
by  Manassein  in  1880.  Next  to  the  Vratck  comes  the 
Russkaya  Medicina  and  the  Meditsinski  Vestnik.  An- 
other excellent  journal,  composed  principally  of  ab- 
stracts, but  containing  also  some  original  aricles,  is  the 
Mediisinskoyc  Obosrenoyc,  The  organ  of  the  German 
physicians  is  the  St,  Pctershurger  Medicinische  Wochcn- 
schrift  The  writer  says  that  medical  journals  are  not 
subject  to  the  censorship  of  the  press,  but  this  seems  to 
be  an  error,  for  the  last-named  journal  always  bears  the 
imprimatur  of  the  censor.  At  one  time  there  were  many 
female  medical  students  attending  a  college  of  their  own, 
but  lately  they  have  been  frowned  upon  by  the  Govern- 
ment (probably  by  reason  of  the  Nihilist  fright),  and  now 
their  college  is  in  a  fair  way  of  extinction.  The  students 
for  the  most  part  lived  a  miserable  life,  half  starved  and 
half  frozen,  and  their  condition  was  not  much  improved 
after  they  had  finished  their  studies.  They  had  no  as- 
sured standing  among  physicians,  and  usually  practised 
in  the  country  districts  and  among  the  poorest  classes. 

The  Properties  of  Crotalus. — Crotalus,  the  poison 
of  the  rattlesnake,  is  obtained  from  the  crotalus  horridus. 
Physiological  action  :  Inoculation  causes  ecchymoses  and 
hemorrhages,  by  putting  an  end  to  the  coagulating  power 
of  the  blood,  with  febrile  heat,  anorexia,  injected  con- 
junctiva, etc.  Therapeutical  uses  :  It  was  originally  in- 
troduced by  homoeopaths,  and  has  been  employed  for 
malignant  hemorrhagic  scarlatina  on  the  principle  "  similia 
similibus  curantur."  Preparations  and  doses:  The  poi- 
son-bag. is  removed  from  the  living  vipers,  and  then 
mixed  with  glycerine  as  a  preservative.  Crotalus  is  pre- 
pared in  decimal  strengths,  the  menstruum  used  being  one 
part  of  glycerine  to  three  parts  of  proof  spirit ;  the  three 
decimal  dilution  is  chiefly  used.  Dr.  Havard,  of  I^iver- 
pool,  prescribed  three  drops  in  a  spoonful  of  water  every 
three  or  four  hours  in  malignant  hemorrhagic  scarlatina. 
It  is  also  used  hypodermically  in  doses  of  one  to  three 
minims. 

The  Abuse  of  Tonics. — Dr.  Alfred  W.  Perry,  of  San 
Francisco,  Cal.,  writes :  **  The  abuse  of  tonics  is  most 
notably  seen  in  rather  stout  persons  over  forty  years  old. 
Such  persons,  without  any  serious  organic  disease,  com- 
plain of  weakness  or  fatigue  after  slight  exertion,  pains 
in  the  limbs,  vertigo,  and  perhaps  of  shortness  of  breath  ; 


and  as  they  are  frequently  rather  pale,  tonics  and  stimu. 
lants  are  prescribed  for  them.  The  appetite,  and  thereby 
the  body-weight,  majr  be  increased,  but  the  symptoms 
complained  of  remain  or  are  aggravated.  Let  us  take 
up  each  symptom  and  analyze  it.  Normally  fatigue  is 
due,  according  to  late  researches  of  Voit  and  Petten- 
koffer,  to  an  accumulation  in  the  muscle  of  the  products. 
of  destructive  metamorphosis  (lactic  add,  creotine  add, 
phosphate  of  potassium,  sarcosine)  produced  by  exercise, 
and  partly  to  a  decrease  of  the  oxidizable  muscular  sub- 
stance. By  rest,  normally,  the  blood-current  washes 
out  these  waste  products,  and  the  more  nearly  the  blood 
approaches  a  standard  healthy  condition,  the  more  quickly 
does  this  take  place.  The  amount  of  food  consumed  by 
an  adult  should  be  just  what  is  required  to  keep  up  an 
average  body-weight  (in  proportion  to  height),  and  will 
vary  with  the  work  performed.  An  excess  of  food 
digested  and  absorbed  produces  a  blood  too  rich,  thick, 
and  imperfectly  oxidized.  This  condition  is  generally 
marked  by  a  deposit  of  reddish  urates  in  the  urine  when 
cooling.  An  addition  to  the  blood  in  such  a  conditioD 
of  large  quantities  of  water  (by  drinking)  enables  it  lo 
dissolve  more  easily  these  waste-products  of  muscle,  and 
so  produces  a  feeling  of  renewed  strength.  Witness  the 
increase  of  uterine  action  in  labor  after  drinking  freely 
of  any  kind  of  tea  ;  the  vigor  produced  in  the  plethoric 
or  gouty  by  drinking  freely  any  kind  of  mineral  water, 
and  using  low  diet ;  the  undoubted  benefit  of  the  present 
fashion  of  drinking  freely  of  hot  water  has  the  same  ex- 
planation.  The  muscular  pains  are  a  slight  kind  of 
cramp  or  muscular  rheumatism,  which  is,  as  Anstie  (in 
his  work  on  neuralgia)  defines  it,  ^pain  produced  in  a 
muscle  obliged  to  work  when  its  structure  is  imperfecUj 
nourished  or  impaired  by  disease,^  The  short  breath  d^ 
pends  on  a  relative  insufficiency  of  the  heart's  action. 
The  heart,  without  being  at  all  diseased,  is  often  incapabk 
of  maintaining  the  circulation  properly  with  its  incidental 
variations.  Let  us  take  the  example  of  a  man  five  feet 
eight  inches  in  height,  one  hundred  and  fifty  pounds  in 
weight,  and  let  him  increase  in  weight  to  two  hundred 
pounds  while  performing  a  moderate,  and  perhaps  a  de- 
creasing amount  of  labor.  His  heart  is  unable  to  propel 
the  blood  properly  through  the  area  of  two  bundled  pounds 
of  body-weight,  involving  about  twenty-five  per  cent,  more 
work,  because  the  heart-muscle  has  not  increased  in  bnlk 
and  vigor  at  all.  If  this  man's  weight  had  increased  while 
performing  hard  work,  we  might  be  sure  that  the  cardiac 
muscle  had  grown  in  proportion.  Any  sustained  increase 
of  tension  of  the  circulation  causes  a  physiological  hyper- 
trophy of  the  heart.  But  where  the  body-weight  increases 
with  a  decrease  of  labor,  and  an  increase  of  food  or 
alcoholic  stimulants,  we  may  be  sure  that  there  has  been 
no  physiological  cardiac  hypertrophy.  The  vertigo  often 
met  with  in  these  cases  may  be  the  result  of  a  cere- 
bral anaemia.  This  when  conjoined  to  pallor  is  usually 
an  indication  for  tonics  and  iron.  There  is  no  poverty 
of  the  blood  or  general  anaemia,  the  surface  is  pade  from 
insufficient  filling  of  the  capillaries  from  want  of  heart 
vigor.  The  conditions  above  cited  need  a  treatment  en- 
tirely opposed  to  a  tonic  one.  They  need  alkalies  to 
assist  in  breaking  down  tissue,  plenty  of  water  to  carry  ! 
away  the  broken-down  tissues,  and  a  little  increase  in  ' 
exercise  with  a  restricted  diet."  i 

Harvey  as  a  Student  of  Nature. — In  the  Harveian  ! 
oration  for  this  year  Dr.  Reynolds  lays  stress  upon  the 
fact  that  Harvey  was  always  studying  and  seeking  to 
interpret  nature.  **  He  was  one  of  her  keenest  and  most 
devout  interpreters ;  in  reverence  he  knelt  before  her, 
and  asked  her  questions  ;  he  cross-examined  her,  but  in 
no  unfriendly  tone.  Nature  to  him  was  a  perfect  verity,  , 
the  one  witness  that  could  never  be  absorbed  or  shaken, 
the  one  witness  in  whom  there  could  be  no  false  way, 
the  one  witness  who  could  not  lie.  And  by  such  a 
method  only  must  science  ever  be  advanced ;  it  is  thus 
that  great  discoveries  are  to  be  achieved,  thus  that  we 
must  seek  to  leave  our  footsteps  on  the  sands  of  Time." 


INDEX. 


Abdominal  section,  383. 
Abortion,  574 ;  and  nitrite  of  amyl,  621. ' 
Abscess,  muscular  rupture  simulating,  682 ; 
of  frontal  sinus,  163 ;  of  the  cerebellum, 
404;   of  the  liver,  580;   orbital,  162; 
perinephritic,  23. 
Academy  of  Medicine  of  Paris,  77,  107. 
A.  C.  £.  mixture,  the,  nitrous  oxide,  and 

ether,  712. 
Acid,  borophenylic,  38;  carbolic,  in  rheu- 
matism, 10 ;  hydriodic,  in  hay  asthma, 
259;   hydrobromic,    222;    lactic,    191; 
osmic,  in  epilepsy,   317;    oxalic,  222; 
picric,  222  ;  salicylic,  in  lupus,  541 ;  va- 
lerianic, 222. 
Accommodation  and  presbyopia,  586. 
Acetabulum,  fracture  of,  576. 
Acne,  628. 
Actinomycosis,  26. 
Adams,  the  late  Dr.  J.  G.,  18. 
Addison's  disease,  697. 
Adenitis,  strumous,  treated  by  nitrate  of  aH- 

▼er.  375. 
Adenol3rm  phangitis,  uterine,  333. 
Adenoma,  of  the  liver,  706. 
Adenopathies,  scrofulous,  10. 
Adonis  vemalis,  192. 

Agnew,  Dr.  C.  K.,   hydrochlorate  of   co- 
caine, 438. 
Air-passages,  foreign  body  in,  552. 
Ankle  clonus  and  patellar  reflex,  403. 
Albumen,  in  urine,  delicate  tests  for,  94. 
Albuminuria,  functional,  305 ;  hepatic,  124  ; 
in  pr^;nancy,   331  ;  physiological,   10 ; 
regiilatory,  601. 
Alcohol*  378. 
Alcoholism,  chronic,  681. 
Alimentary  canal,  nervous  origin  of  some  dis- 
orders of,  481. 
Alt,  Dr.  Adolph,  notice  of  book  by,  299. 
Althaus,  Dr.  Julius,  notice  of  boolc  by,  692. 
Alum,  139. 

Amaurosis,  unilateral,  66. 
American  Academy  of  Medicine,  411. 
American  Gynecological  Society,  382;  no- 
tice of  transactions,  1883,  244. 
American  Laryngologiod  Association  viewed 

from  the  outside,  308. 
American  Ophthalmological  Society,  161. 
American  Otological  Society,  105. 
American   Public  Health  Association,  406, 

439- 
Amidon,  Dr.  R.  W.,  notice  of  manual  by, 

495- 

Ammonia,  muriate  of,  307. 

Anmioniac,  gum,  221. 

Ammonii,  boras,  139  ;  phosphas,  139. 

Amyl,  nitrite  of,  and  abortion,  621 ;  nitrite 
of,  in  anamoniacal  urine,  12  ;  nitrite  of, 
in  opium-poisoning,  13  ;  nitrite  of,  in- 
ternal use  of,  308. 

Anaemia,  essential,  431  ;  following  hemor- 
rhage, 301 ;  pernicious,  301 ;  pernicious, 
in  children,  293;  iron  albuminate  in, 
140. 

Anaesthesia,  of  the  trigeminus  with  trophic 
ulceration  of  the  helix,  698  ;  rectal,  72  ; 
surgical,  378. 

Anaesthetic,  whiskey  as  an,  588. 

Anaesthetics,  in  St.  Petersburg,  42. 

Andrews,  T>r.  Joseph  A.,  jequirity  ophthal- 
mia, 596. 

Aneurism,  aortic,  263,  699 ;  inguinal,  166 ; 
miliary  of  the  stomach,  97,  293. 

Angeiomatous  growths,  treatment,  28. 

Angina  pectoris,  559. 

Anteflexion  of  the  uterus,  693. 

Antipyrin,  56,  245,  303,  713;  exanthem  fol- 
lowing the  use  of,  317;  in  diseases  of 
children^  293. 

Antipyresis,  493 ;  by  inunction,  37. 

Antipyretic,  515. 

Antisuppurative,  700. 

Aphasui,  from  indigestion,  543 ;  peculiar 
forms  of,  12  ;  sensory,  556. 


Apocynum  cannabinum,  6^. 
Apomorphia,  139 ;  and  epilepsy,  598. 
Arachnoid,  lipoma  of,  707. 
Army  surgeons,  shall  they  practise  outside  ? 

.      475. 

Arsenic,  m  generalized  sarcoma,  431. 

Arteries,  coronary,  sclerosis  of,  682. 

Arteritis,  obliterous,  99 ;  syphilitic,  599. 

Arthropathies,  multiple  spinal,  67. 

Aseptoi,  a  new  antiseptic,  600,  712. 

Asphyxia,  56. 

Asthenopia,  390. 

Astringents,   in    ophthalmic  practice,   482, 

499. 
Ataxia,  hereditary,  67  ;  locomotor,  265. 
Atropine,   at  the   beginning  of  convergent 

squint,  389. 
Auricles,  cardiac,  function  of,  575. 
Averill,  Dr.,  tridiinosis,  14a 


B 


Baby- farming,  154. 

Bacilli,  cultivation  of,  56 ;  in  calcareous  con- 
cretions of  the  lungs,  681 ;  tubercle,  in 
the  urine  and  kidneys,  191. 

Bacillus  of  syphilis.  687  ;  tuberculosis,  274. 

Baird,  Dr.  W.  T.,  electricity  in  pleuritic 
effusion,  476. 

Baker,  Rev.  Geo.  S.,  correspondence,  446. 

Baker,  Dr.  Henry  B.,  age  of  greatest  risk 
from  consumption,  235. 

Baldness,  84. 

Baldwin,  Dr.  B.  I.,  immunity  of  the  n^;ro 
from  trachoma,  704. 

Baldwin,  Dr.  D.  A.,  dysentery,  433. 

Barker,  Dr.  Fordyce,  709,  717. 

Barnes'  dilator,  modification  of,  529. 

Baruch,  Dr.  Simon,  224;  tracheotomy  in 
croup  and  diphtheria,  534,  700. 

Baths,  carbonic- water,  13 ;  cold,  in  the 
treatment  of  puerperal  fever,  333 ;  for 
the  poor  in  winter,  409 ;  for  use  during 
the  year,  418. 

Beard,  Dr.  Geo.  M.,  book  notice  [posthu- 
mous MS.],  300. 

Bell's  law  discovered  by  Magendie,  600. 

Bellevue  Hospital  Medical  College,  711. 

Bemiss,  Dr.  Samuel  M.,  notice  of  death  of, 

«      571. 

Benzoin,  168. 

Bergh  and  Pasteur,  18. 

BerUn  Society  of  International  Medicine,  52, 
191,  245. 

Billings,  Dr.  Frank  S.,  book  notice,  216. 

Billings,  Dr.  John  S.,  book  notice,  524. 

Binnie,  Dr.  John,  artificial  feeding  of  infants, 
287. 

Binz,  von,  Prof.  C,  notice  of  book  by,  19. 

Biological  Society  of  Paris,  78,  108,  193, 
246. 

Black,  Dr.  G.  V..  notice  of  book  by,  691. 

Blackweli,  Dr.  FJizabeth,  book  notice,  495. 

Bladder,  aspiration  of,  236 ;  cider  as  a  pro- 
phylactic in  stone  of  the,  10 ;  extraction 
of  foreign  bodies  from,  184  ;  exstrover- 
sion  of,  362;  foreign  bodies  in ,  432 ; 
injections  of,  269 ;  local  use  of  ether  in 
the,  25 :  nitrate  of  silver  injections  of 
the,  501. 

Blindness,  fulminating,  161 ;  in  infancy,  10. 

Blood,  condition  of,  in  hydrophobia,  266; 
transfusion  of  peptonized,  108 ;  trans- 
fusion of,  is  it  justifiable?  708. 

Blood-poisoning  from  human  bites,  682. 

Blood-vessels,  physio-pathology  of  the,  69. 

Bodenhamer,  Dr.  William,  the  rectum  a  re- 
ceptacle for  excremental  matter,  309. 

Body,  human,  motor  power  of,  476. 

Bones,  brittle,  la 

Borax,  in  contagious  diseases,  266. 

Borcheim,  Dr.  L.  E.,  tape-worm,  429. 

Bosworth,  Dr.  F.  H.,  a  new  therapeutic  use 
for  cocaine,  533 ;  the  three  tonsils,  365. 

Bow-legs,  612. 


Boyland,  Dr.  G.  Halsted,  Florida  climate, 

109. 
Brachydactylus,  symmetrical,  377. 
Bradner,  Dr.  Wm.  B.,  climate  of  Florida, 

83. 
Brain,  abscess  cavities  in  the,  235;    bony 

tumor  of,  707  ;  cortical  lesions  of  the, 

237;  fourth  ventricle,  249;  pressure,  in 

public  schools,  402. 
Breast,  tubercles  of  the,  39 ;  tumor  of,  554. 
Breath^g,  buccal,  565. 
Breech,  cases,  579. 
Bright' s  disease,  dyspncea  of,  681 ;  of  malarial 

origin,  237. 
British  Medical  Association,  126,  131,  i6o^ 

217. 
Bronchitis,  542. 

Brown,  Dr.  R.  Wood,  dead  teeth  in  jaws, 
«      564. 
Browning,    Dr.    William,     pseudo  -  bulbar 

paralysis,  487. 
Buboes,  suppurating,  376. 
Buck,  Dr.  Albert  H.,  deafness  of  supposed 

syphilitic  origin,  257. 
Bundy,  Dr.  A.  D.,  death  from  the  introduc- 
tion of  a  stomach-tube,  504. 
Burke,  Dr.  John,  251. 
Burnett,  Dr.  Charles  H.,  notice  of  book  by, 

691. 
Bums,  97. 
Burq,  Dr.,  death  notice,  241. 


Caesarean  section,  329. 

Caffeine,   191,  491. 

Calculi,  renal,  removal  by  manipulation,  587. 

Calculus,  biliary,  passed  by  the  rectum,  599 ; 
impacted  in  the  ureter,  541. 

Calomel,  in  diphtheria  and  croup,  36 ;  in 
diseases  of  the  eye,  38 ;  m  the  treatment 
of  pneumonia,  683. 

Campbell,  Dr.  S.  E.,  306. 

Cancer,  early  recognition  of,  135 ;  from  ci- 
catrices in  the  stomach,  270;  of  the 
breast,  670;  of  the  pancreas,  532;  of 
the  stomach,  385,  469 ;  of  the  stom- 
ach and  pancreas,  593  ;  statistics  in  Eng- 
land, 223;  vaginal  hysterectomy  for,  3814. 

Canfield,  Dr.  H.  A.,  448. 

Cannibalism,  is  it  necessarily  murder  ?  531. 

Capsule,  internal  (brain),  477. 

Carcinosis,  general,  552. 

Cardiopathy,  of  menopause,  347. 

Carman,  Dr.  J.  H.,  opium-smoking,  501. 

Carotid,  ligation  of  common,  456. 

Carhart,  Dr.  J.  W.,  correspondence,  475. 

Case,  Dr.  Meigs,  special  disease  of  spinal 
curvatures,  701. 

Cataract,  artificial  maturation  of,  388  ;  nat- 
ural history  of,  162. 

Catarrh,  chronic  intestinal,  573;  intestinal, 

432. 

Catheter,  passage  of,  456. 

Cauldwell,  Dr.  C.  M.,  manaca  in  rheuma- 
tism, 31. 

Caustics,  in  ophthalmic  practice,  482,  499. 

Cauterizations,  punctate,  51. 

Cephalhydrocele,  traumatic,  236. 

Cerebellum,  abscess  of,  404;  the  first  total 
removail  of,  in  a  dog,  711  ;  morphologi- 
cal status  of  the,  iii,  249. 

Cerebral  localization,    146,  232,  342,  458, 


536. 
ebrun 


Cerebrum,  an^miantsand  hyper6miants,  112. 

Cesspools,  10 1. 

Chamberlain,  Dr.  C.  W.,  death  notice,  241. 

Chamberlain,  Dr.  William  M.,  correspond- 
ence, 664. 

Chancre,  excision  of,  36a 

Chapman,  Dr.  Henry  C,  book  notice,  216. 

Chapin,  Dr.  Henry  Dwight,  the  prevention 
of  summer  complaint,  87. 

Charles,  Dr.  T.  Cranstown,  notice  of  book 
by,  692. 

Cheesman,  Dr..  W.  S.,  supernumerary  tes- 
ticles, 196. 


720 


INDEX. 


[December  27, 1884. 


Chesney,  Dr.  J.  Portman,  book  notice,  244. 

Children,  convulsions  in,  543. 

Childs,  Dr.  S.  B.,  dysentery,  223. 

Chill,  in  pneumonia,  13. 

Chloroform,  dosimetric  administration  of, 
39 ;  for  tape-worm,  ii2,  308,  475,  601 ; 
narcosis  maintained  for  eight  days,  108. 

Chloral,  oleate  of,  for  pruritus,  543. 

Chloral-quinine,  196. 

Chlorosis,  301. 

Cholecystotomy,  $16. 

Cholera,  Asiatic,  73,  100,  130, 156,  245,  260, 
440,  522,  548,  550,  589, 661 ;  and  cholera 
nostras,  604 ;  and  the  comma-bacillus, 
53,  241,  267  ;  and  its  prevention,  40  ; 
and  rags,  571  ;  and  syphilis,  385  ;  and 
the  Cabinet,  98 ;  and  tubercle  bacillus, 
31  ;  at  Suspension  Bridge,  1854,  556; 
bacillus,  Koch^s  defence  of,  602 ;  cause 
of,  IX ;  copper  as  a  prophylactic,  5x2  ; 
French  commission,  467  ;  further  contri- 
butions to,  687  ;  germ,  211,  350  ;  infan- 
tum, 357  ;  influence  on,  by  syphilis  and 
mercury,  447  ;  in  Europe,  16 ;  in  India, 
255  ;  in  Toulon,  107  ;  intravenous  in- 
jections in,  688;  limitations  of  knowledge 
regarding,  570 ;  microbe  of,  295  ;  pre- 
vention of,  167;  quarantine  in,  570; 
sulphuric  acid  in,  386 ;  the  germ  and  its 
destruction,  251. 

Chordee,  6co. 

Christian,  Dr.  E.  P.,  placenta  praevia,  89. 

Cider,  as  a  prophylactic  in  stone  of  the  blad- 

^!|;der,  10. 

Cinchonidia,  532 ;  sulphate  of,  72. 

Circulation,  discovery  of  the,  224. 

Cirrhosis  of  the  liver,  697  ;  of  the  pancreas, 

505. 

Civil  service  and  the  medical  profession,  407. 

Clavicle,  fracture  of,  527. 

Clay,  Dr.  Charles,  one  of  the  revivers  of 
ovariotomy,  713. 

Clitrophobia,  403. 

Club-foot,  277. 

Coca,  491. 

Coca-leaf  and  its  alkaloid,  51a 

Cocaine,  muriate  of,  153,  417,  438,  534,  550, 
577,  604,  656,  715  ;  a  new  therapeutic 
use  for,  533  ;  early  employment  of,  659  ; 
failures,  658 ;  first  enucleation  of  the 
eye  under,  713 ;  history  of  properties  of, 
5x8;  in  dentistry,  657;  in  general  sur- 
gery, 657  ;  Knapp's  experiments,  461, 
463 ;  in  gynecology,  489,  658 ;  in  intra- 
nasal surgery,  654;  in  minor  surgery, 
582. 

Cold,  in  therapeutics,  397,  414. 

Colic,  clinical  forms  of  hepatic,  686. 

Collodion,  iodized,  in  erysipelas,  517. 

Color-perception,  96. 

Colotomy,  97,  541,  542. 

Column  of  GoU,  478. 

Coma,  diabetic,  9  ;  d3rspeptic,  516. 

Comma-bacillus,  240,  260,  381,  416,  436. 

Compensation  of  physicians,  law  governing 
the,  626. 

Concussion  of  the  spine,  6x7,  634. 

Congestion,  cerebral,  during  mental  work, 
308. 

Conjunctivitis,  482;  purulent,  266. 

Constipation,  43  x  ;  ergot  in,  37. 

Consumption,  prevalence  of,  at  different 
ages  of  life,  527  ;  when  is  the  risk  from, 
greatest  ?  36,  194,  235,  335. 

Consumptives,  North  Carolina  climate  for, 

364 

Contagiousness,  duration  of,  after  acute  in- 
fectious diseases,  573. 

Contusions,  decoction  of  valerian  in,  598. 

Convulsions,  in  children,  236,  543  ;  of  the 
tongue,  509 ;  puerperal,  46,  576. 

Cook  County  Hospital,  401. 

Copper  and  cholera,  512. 

Copper-colored  spots  on  the  forehead,  56. 

Cord,  umbilical,  tying  of,  166. 

Cornea,  local  anaesthetic  to  the,  417  ;  result 
of  great  loss  of  substance  of,  389. 

Coming,  Dr.  J.  Leonard,  book  notice,  216. 

Corns,  cure  for,  672. 

Corpulence,  book  notice,  524. 

Corrosive  sublimate,  196;  solutions,  168; 
tolerance  of  small  closes  9f,  3x2. 

Coryza,  X3. 


Cough,  vapor  of  glycerin^  for,  403. 

Country  doctor,  464,  473. 

Cowan,  Dr.  George,  modification  of  Barnes' 

dilator  529. 
Crawcour,  Dr.  J.  L.,   iodide   of  ]X)tassium, 

584. 
Cremation,  140,  571 ;  in  London,  28. 
Cretinism,  in  adults,  302. 
Crime  and  madness,  547. 
Croom,  Dr.  J.  Halliday,  notice  of  book  by, 

2a 
Crotalus,  7x8. 

Crothers,  Dr.   T.   D.,  acute  impulsive  ine- 
briety, 289. 
Croup,  357 ;   calomel  in,   36 ;  diphtheritic, 

580,  697 ;  tracheotomy  in,  643, 645,  665, 

700. 
Crudeli,   Dr.  Conrad   Tommasi,  address  at 

the    International    Medical    Congress, 

Cuirass,  for  Potts'  disease,  13. 

Cuming,  Dr.  James,  address,  British   Medi- 

cal  Association,  1884,  X69. 
Curette,  uterine,  578. 
Cyr,  Dr.  Jules,  book  notice,  216. 
Cysticercus  in  the  vitreous,  703. 
Cystitis,  545 ;  intravesical  injections  for,  704 ; 

naphthaline  in,  597. 

D 

DaCosta,  Dr.  J.  M.,-  notice  of  book  by,  19. 

Dacro-adenitis,  X64. 

Dana,  Dr.  C.  L.,  concussion  of  the  spine, 

6x7. 
Dana,  Dr.  S.  W. ,  delirium  following  the  use 

of  morphine,  64. 
Dandruff,  376. 

Daniell,  Dr.  Alfred,  book  notice,  244.   • 
Davis,  Dr.  G,  G.,  corrosive  sublimate,  196. 
Deafness,  new  apparatus  for  the  relief  of,  38 ; 

sudden,  caused  by  mumps,  517  ;  sudden, 

of  supposed  syphilitic  origin,  257. 
Death,    706;    diagnosis  of  apparent,  293; 

sudden,  in  chUd birth,  36  x. 
Death-rate,  of  New  York,  X5. 
Decapitation,  does  it  cause  instant  death? 

531. 

Deformities,  rachitic,  of  the  lower  extremi- 
ties, 612. 

Deliriimi  following  the  use  of  morphine,  64. 

Delirium  tremens,  paraldehyde  in,  39. 

Delusions,  therapeutical,  379. 

Dentistry,  43. 

Dermatology  at  Vienna,  56. 

Deutsch,  Dr.  Solomon,  book  notice,  299. 

Diabetes,  231,  580,  600,  705 ;  coma  of,  9. 

Diabetics,  expired  air  of,  and  iodoform,  515. 

Diaphragm,  rupture  of,  402. 

Diarrhoea,  575  ;  chronic,  sea  voyage  in  cer- 
tain cases  of,  5x2  ;  naphthaline  in,  597; 
nervous,  12 ;  treatment  of,  99. 

Dickinson,  Dr.  D.,  ascites,  588. 

Diet,  infant,  X4. 

Digitalis,  X9X  ;  physiological  action  of,  5x6. 

Dignity,  professional,  586. 

Diphtheria,  and  croup,  697 ;  calomel  in,  36  ; 
experimental,  544 ;  tracheotomy  in,  700. 

Diplomas  of  the  United  States  Medical  Col- 
lege, 249. 

Disease,  causes  of,  X69. 

Disease  germs,  451. 

Dissection,  the  laws  of,  486. 

Doctor,  in  fiction,  X82. 

Doughty,  Dr.  S.  W.  H.,  cocaine  in  gyne- 
cology, 658. 

Drinking-water,  purification  of,  236. 

Drops,  the  weight  of,  377. 

Druggist  and  drug  appraiser,  26. 

Drugs,  explosive,  599. 

Dugas,  Dr.  Louis  A.,  notice  of  death  of, 
468. 

Dumm,  Dr.  S.  C,  plea  for  the  country  prac- 
titioner, 473. 

Dupuytren*s  finger  contraction,  276,  375. 

Dwight,  Dr.  Francis  M.,  hospital  report, 
264. 

Dysentery,  223 ;  homoeopathic  treatment  of, 
433  ;  micrococci  of,  404. 

Dyspepsia,  dietetic  treatment  of,  575 ;  treat- 
ed with  hot  water,  563. 

Dyspnoea  in  Bright's  disease,  681. 

Dystocia,  from  cervical  fibroids,  383. 


Ear,  diseases  of,  3;  external,  X19,  173;  j^. 

fluence  of  dental  irritation  on  the,  107  • 

practical   observations  on  the  human! 

X49  ;  quacking  sounds  in,  130 ;  ulcera. 

tions  of,  with  anaesthesia  of  the  trigem* 

inus,  688. 
Ears,  pain  in,  due  to  irritation  in  thejavs, 

374. 
Earle,  Dr.  Charles  W.,  cirrhosis  of  the  paa. 

creas,  505. 
Ecchymosis,  of  nervous  origin,  403. 
Eczema,  and  trophic  centres,  485. 
Edson,   Dr.   Benjamin,  morphia  in  cardiie 

disease,  40X. 
Edson,  Dr.  Cyrus  A.,  new  spray-producer 

306. 
Education,  of  children  with  defective  hetr- 

ing,  675. 
Effusion,  pleuritic,  598. 
Electricity,  in  elephantiasis,  598 ;  in  hydnr- 

throsis,  69 ;   in   treatment  of  pleuritic 

effusion,  476 ;    the   induced  current  in 

pleuritic  effusions,  266;  the  therapeuti* 

cal  value  of,  710. 
Electrolysis,  in  stricture,   94,  X95,  250;  m 

treatment  of  uterine  tumors,  329. 
Elephantiasis,   and  electricity,   598;  scroti, 

629. 
Ellingwood,  Dr.  Finley,  tape-worm,  82, 
Elliott,  Dr.  A.  A.,  injury  from  a  pitchfork, 

429. 
Emmet,  Dr.  T.  A.,  notice  of  book  by,  69a 
Encephalitis,  acute,  of  children,  696. 
Endarteritis,  ulcerative,  50. 
Endocarditis,  ulcerative,  554. 
Enterotomy,  6ox. 
Epery,  Dr.  F.  W.,  225. 
EpUepsy,  and  apomorphia,  598;  osmic  add 

iOi  3*7  ;  puerperal,  351 ;  treatment,  213. 
Epileptics,  the  pupils  in,  39. 
Epley,  Dr.  F.  W.,  cancer  of  the  ponaeU) 

532. 
Epithelioma,  of  the  auricle,  107. 
Ergot,  in  constipation,  37. 
Ether,  acetic,  22 x  ;  formic,  222 ;  hydiiodic, 

22  X  ;  hydrobromic,  221  ;  hydrochloric, 

221  ;  inhalation  of,  64. 
Etherization,  rectal,  224.  252,  326,  346. 
Etiquette,  breach  of  professional,  588. 
Ethmoid,  disease  of,  106. 
Evans,  Dr.  S.  A.,  menstruation  in  animalSi 

588. 
Extracts,  fluid,  92. 
Extra-uterine  pregnancy,  224,  33X. 
Eye,  artificial,  389 ;  calomel  in  diseases  of, 

38  ;  changes  in,  immediately  after  death, 

163 ;    dropping  fluids   into,  675 ;  fiist 

enucleation  of  the,  under  cocaine,  713; 

tuberculosis  of,  681. 
Eyeball,  staphylomatous,  93. 


Fable,  a  medical,  587. 

Faradization,  in  obstetric  practice,  544. 

Farcy,  107. 

Feeding,  infaiits,  351. 

Feet,  sweating  of,  97. 

Fever,  chlorotic,  37;  intermittent,  excited 
by  intestinal  worms,  3x7  ;  malarial  327; 
malarial,  morbid  anatomy,  68 ;  p1lHp^ 
ral,  X4X  ;  puerperal,  cold  baths  in,  }^; 
puerperal,  in  Denmark,  332 ;  pucrpeni, 
prophylaxis  in,  38;  substitute  for  tic 
cold  bath  in,  ii ;  typhoid,  696 ;  typhoid, 
and  syphilis,  385 ;  typhoid,  grave  ncrroas  • 
symptoms  in,  517  ;  typhoid,  mild  fonns 
of,  404;  typhoid,  polyuria  in  coonkS' 
cence,  265  ;  typhoid,  rational  Ireatmat 
of,  629 ;  typhoid,  rose^colored  enptin 
not  characteristic  of,  707;  typhoid, 
symptomatic  treatment  of,  597;  tf 
phoid,  the  apyretic  form  of,  97 ;  typho- 
malarial,  327;  typhus,  339;  yellow,  7» 
264 ;  yellow,  at  Panama,  509 ;  yellow, 
micro-organisms  of,  168;  yellow,  the 
origin  o^  435. 

Fibroids,  cervical,  as  a  cause  of  dystocia,  3S3. 

Fibro-sarcoma,  naso-pharyngeal,  455,  46^ 

Fisk,  Dr.  Samuel  Aug.  Loomis,  on  CoIondB 
climate,  526. 


December  27,  1884.] 


INDEX. 


721 


Fistula,  in  ano,  539. 

Florida,  as  a  heidth  resort,  502  ;  climate  of, 
83,  109,  280,  308. 

Foetus,  gastric  secretion  in,  376. 

Food  for  the  febrile,  95. 

Forceps,  a  new  bullet,  419 ;  in  breech  pre- 
sentations, 308;  the  obstetric,  in  breech 
presentations,  607. 

Forearm,  rotation  of,  599. 

Formulary  of  unofficinsd  preparations,  21. 

Foster,  Dr.  Joel,  Obltnary,  i8. 

Fothergill,  Dr.  J.  Milner,  affections  of  the 
heart,  i,  29,  57,  86. 

Fowler,  Dr.  George  B.,  a  plea  for  the  use 
of  delicate  tests  for  albumen  in  urine, 
94;  "The  Haemorrhoid  Quack,"  527. 

Fowler,  Dr.  George  R. ,  neurectomy  for  re- 
moval of  facial  neuralgia,  368. 

Fracture,  of  the  acetabulum,  576;  of  the 
clavicle,  527. 

Freckles,  432. 

Free,  Dr.  Spencer  M.,  hysteria  in  the  male, 
346. 

French,  Dr.  C.  JEi.,  maternal  impression,  140. 

Fresh  air  supply  for  cities,  560. 

Fright,  mental  states  induced  by,  530. 
Fuller,  Dr.  Fraser  C. ,  rattlesnake-poisoning, 

137. 
Fuller,  Dr.  S.  £.,  pseudo-bulbar  paralysis, 

487. 
Furuncle,  68. 


Galentin,  Dr.  C.  B.,  notice  of  book  by,  299. 

Galvanism,  in  tubal  pregnancy,  337.     . 

Gant,  Dr.  F.  J.,  notice  of  book  by,  2a 

Gardiner,  Dr.  Henry  K.,  308. 

Garrigues,  Dr.  H4  J.,  tubal  pregnancy,  446. 

Gas,  illuminating,  poisoning  by,  291. 

Gastraljgia,  malaxial,  288. 

Gastritis,  chronic,  54a 

Gastrostomy,  95. 

Gatchell,  Dr.  Edwin  A.,  the  North  Carolma 

climate  for  consumptives,  364. 
Geddings,  Dr.  W.  H.,  indigenous  leprosy, 

177. 
Gelsemiiun,  in  tetanus,  34. 
Genu  valgum,  276. 

German  Naturalists  and  Physicians,  696. 
Giddings,  Dr.  W.  P.,  251. 
Glioma  of  the  retina,  163. 
Glycerine,     vapor    of,   644;    vapor  of,  for 

cough,  403. 
Glycosuria,  230. 
Goitre,  present  status  concerning  treatment, 

602  ;  removed  by  operation,  671. 
Goldsmith,    Dr.  Middleton,    cancer  of  the 

stomach  and  pancreas,  593. 
Goll,  column  of,  478. 
Gonorrhoea,    77,  600;  potassa  chlorate  in, 

272  ;  stigpmata  maidis  in,  280. 
Goodwiiiie,   Dr.  D.  H.,  a  simple  stomach- 
pump,  305. 
Goodwin,  Dr.  Charles  H.,  notice  of  book  by, 

692. 
Greaves,  Dr.  Thomas,  correspondence,  584. 
Greely,  Lieut.,  rescue  of,  206. 
Green,   Dr.    Edward  H.,  medical  history  of 

L,ady  Franklin  Bay  expedition,  254. 
Green,  Dr.  T.  Henry,  book  notice,  300. 
Groat,  Dr.  F.  A.,  eczema,  485. 
Gross  memorial  professorship,  239,  33a 
Guarana,  4.91. 
Gums,  the  landng  of  children's,  615. 


H 


Hallucinations,  bilateral,  108. 

Hamamelis,  Virginiana,  53. 

Hamilton,  Dr.  Allan  McLane,  iron  albumi- 
nate in  anaemia,  140. 

Hanks,  Dr.  H.  T.,  notice  of  day-book  by, 
46. 

Harlan,  I>r.  A.  W.,  "dead  teeth  in  jaws/' 

-♦73-  ^  .      ,       . 

Harris,    Dr.    R.  B.,  veratrum  of  gelsemmm 

in  tetanus,  34. 
Harris,   Dr,    M.  L»,  diaphragmatic  hernia, 

40  !• 

Harvey,  as  a  student  of  nature,  718. 
Hawes,  JDr.  Jesse,  scrotal  compressor,  529. 


Hay-fever,  59,  i6S^  225,  259,  427,  476;  in 
an  infant,  503. 

Hseraatoma  auris,  3,  119. 

Haemoglobin,  changes  of,  628. 

Health  bill,  684,  688. 

Health  exhibition,  international,  603. 

Hearing,  defective  in  public  schools,  675 ; 
rapid  loss  of,  106. 

Heart,  affections  of,  i,  29,  57,  86  ;  beats  of, 
600 ;  dilated,  263 ;  iodoform  in  organic 
disease  of,  541;  raorp&ia  in  disease  of 
the,  401 ;  punctured  wound  of,  542  ;  the 
weight  of,  in  cancerous  affections  of  the 
uterus,  265;  ventricles,  centre  of  co- 
ordination for,  358. 

Heat  in  therapeutics,  397,  413. 

Heineman,  Dr.  H.  N.,  was  human  flesh  eaten 
by  any  of  the  Greely  party  ?  216. 

Heinmiiller,  Dr.  R.  J.,  resolutions  on  death 
of,  321. 

Hematocele,  pelvic,  376. 

Hemiplegia,  hysterical,  96. 

Hemorrlmge,  post-partum,  vinegar  in,  66. 

Hemorrhoids,  448,  543;  congenital,  584; 
strangulated,  597. 

Henry,  Dr.  Morris  H. ,  fistula  in  ano,  539. 

Hepatica,  a  useless  drug,  153. 

Hepburn,  Dr.  N.  J.,  cocaine,  534. 

Hermaphrodite,  633. 

Hernia,  after  laparotomy,  543;  congenital 
diaphragmatic,  401 ;  cured  by  sneezing, 
246;  inguinal  kidney  simulating,  698; 
of  the  lung,  489 ;  strangulated,  591, 609; 
traumatic  diaphragmatic,  503. 

Heuel,  Dr.  Franz,  inhalation  of  ether,  64. 

Hiccough,  31. 

Hip,  diseases  of,  168. 

Hippocampus  vs.  hypocampa,  335. 

Histories,  medical,  at  St.  Luke's  Hospital, 
New  York,  419. 

Holden,  Dr.  Edgar,  when  are  we  at  the 
greatest  risk  from  consumption  ?  36 ; 
the  period  of  greatest  risk  from  con- 
sumption, 335. 

Holidays  for  physicians,  348. 

Holt,  Dr.  L.  Emmet,  traumatic  diaphrag- 
matic hernia,  503. 

Honey,  for  small-pox,  293. 

Hooper's  vade  mecum,  book  notice,  524. 

Hoppin,  Dr.  Samuel  B. ,  notice  of  dictionary 
by,  20. 

Horton.  Dr.  W.  P.,  Jr.,  cocaine  in  dentistry, 
657. 

Horwitz,  Dr.  Lloyd  Norris,  t3rphus  fever  at 
the  Philadelphia  Hospital,  339. 

Hospitals  Medical  Society,  Paris,  134,  193, 
385  ;  special  departments  in,  155. 

Howe,  Dr.  J.  Morgan,  *'dead  teeth  in 
jaws,"  444. 

Hubbard,  the  late  Dr.  William  Hustacc,  18. 

Humphreys,  Dr.  C.  H.,  multiple  pregnancy, 
26. 

Hunter,  Dr.  James  B.,  heat  and  cold  in 
therapeutics,  397. 

Hurst,  Lulu,  43. 

Hutchison,  Dr.  J.  C,  book  notice,  524. 

Hydrarthrosis,  and  electricity,  69;  chronic, 
51 ;  of  the  knee-joint.  404. 

Hydrocephalus,  chronic,  705. 

Hydrophobia,  239;  condition  of  blood  in, 
266. 

Hyperhidrosis  of  the  feet,  420. 

Hypnotics,  action  of,  on  the  cerebral  circu- 
lation, 54t^ 

Hypnotism,  artificial,  632. 

Hysterectomy,  vaginal,  for  cancer,  165,  384. 

Hysteria,  gastric,  268,  448 ;  in  the  male, 
346  ;  relations  with  scrofula  and  tuber- 
culosis, 629. 


Imperial  Medical  Society  of  Vienna,  52,  79. 

Induction  coil,  the,  513,  558,  585. 

Inebriety,  acute  impulsive,  289. 

Infancy,  blindness  in,  10. 

Infanticide,  41. 

Infants,  artificial  feeding  of,  287;  feeding, 
528 ;  feeding  with  cow's  milk,  474;  the 
question  of  feeding,  112,  351. 

Infarction,  embolic,  of  muscles,  291. 

Infectious  diseases,  303. 

Injections,  intravesical  for  cystitis,  704. 


Insane,  pauper,  209. 

Insanity,  578,  586. 

Insomnia,  84. 

Instinct,  perverted  sexual,  70. 

Insurance,  life,  25. 

International  Medical  Congress,  182,  (187, 
213,  247,  273.  301,  306,  329.  357,,3«7, 
624.  .M 

Intestinal  obstruction,  326  ;  from  twisting 
of  gut,  196. 

Intiestine,  chronic  catarrh  of,  573 ;  perfora- 
tion of.  304. 

Intestines,  chemical  poisons  formed  within, 
683. 

Inula,  campana,  in  leucorrhoea,  524. 

Investigation,  collective,  of  the  British  Medi- 
cal Association,  685  ;  of  disease,  349. 

Iodine-poisoning,  acute,  387. 

lodism,  acute,  265,  587. 

Iodoform,  515  ;  in  gonorrhoeal  ophthalmia, 
376;  in  organic  disease  of  the  heart, 
541. 

Iridectomy,  cocaine  in,  658. 

Iron,  albuminate  of,  in  anaemia,  140. 

Isolation,  in  the  infant  hospitals  in  Paris, 

ij 

Jarvis,  Dr.  Edward,  death  of,  712. 

Jarvis,  Dr.  William  C,  cocaine  in  intra-na- 
sal  surgery,  654. 

Jaws,  dead  teeth  in,  379,  444, 473,  521,  525, 
564,  650. 

Jequirity,  162,  388,  562 ;  in  Parisian  prac- 
tice, 68;  ophthalmia,  596. 

Jews,  as  physicians,  644. 

Joints,  disease  of,  and  tuberculosis,  578; 
stramonium  leaves  for  painful  affec- 
tions of,  316 ;  sublimate  injections  in  dis- 
eases of,  631 ;  syphilitic  diseases  of,  133; 
tuberculous  diseases  of,  275. 

Jones,  Dr.  H.  McN.,  notice  of  book  by, 
299. 

{ones.  Dr.  S.  S.,  tracheotomy  in  croup,  643. 
udkins,  Dr.  William,  hay  asthma,  259. 


Kales,  Dr.  J.  W.,  substitutes  for  plaster-of- 
Paris  jackets,  705. 

Kelly,  Dr.  J.  D.,  correspondence,  584. 

Keratitis,  388. 

Kesteven,  Dr.  W.  Henry,  book  notice,  300. 

Kidd,  Dr.  George  H.,  address  on  obstetric 
medicine,  141. 

Kidney,  extirpation  of,  79;  inguinal,  simulat- 
ing hernia,  698. 

King,  Dr.  Samuel  T.,  hospital  report,  540. 

Kinnicutt,  Dr.  Frank  P.,  tuberculous  croup- 
ous pneumonia,  399. 

Klein,  Dr.  E.,  notice  of  book  by,  692. 

Klingensmith,  Dr.  I.  P.,  calomel  in  diphthe- 
ria and  croup,  36. 

Knapp,  Dr.  H.,  cocaine,  461,  656,  662. 

Knee-joint,  acute  inflammation  of,  433  ;  ex- 
cision of,  578 ;  hydrarthrosis  of,  404 ; 
removal  of  foreign  body  from,  403. 

Knock-knee,  612. 

Kola  nut,  53. 

Kortright,  Dr.  James  L.,  rupture  of  the.dia- 
p£-agm,  402. 

Kretschmar,  Dr.  Paul  H.,  tape-worm,  82. 


Labor,  sudden  death  in,  706;  the  third 
stage,  331,  608. 

Lady  Franklm  Bay  Expedition,  254. 

Laparomyotomy,  370. 

Laparotomy,  foreign  bodies  in  the  abdomen 
after,  382  ;  hernia  after,  543. 

Lancaster,  Dr.  R.  A.,  280. 

Laryngitis  hemorrhagica,  9. 

Laryngismus  stridulus,  292. 

Larynx,  gangrenous  inflammation  of,  I9l{; 
resorcin  in  affections  of,  543. 

Lata,  601. 

Lawn^tennis,  pathology  of,  464. 

Lead-poisoning,  621,  637. 

Leake,  Dr.  Henry  K.,  nitrate  of  silver  injec- 
tions within  the  bladder,  501. 

Lefferts,  Dr.  George  M.,  notice  of  book  by, 
691. 


•J  2'. 


INDEX. 


[December  27, 1884. 


Leg,  increase  in  the  length  of,  after  rhennuu- 

tism,  10  ;  ulcer  of,  68 1. 
Lemniscus,  the  anatomy  of  the,  393,  421, 

449.  477. 

Leonard,  Dr.  William  R.  A.,  new  bullet  for- 
ceps, 410. 

Leprosy,  156;  indigenous,  177;  bacilli,  and 
vaccination  for  leprosy,  713. 

Letter,  Cincinnati,  582 ;  London,  24,  54, 
80,  13s,  166,  220,  248,  333,  390,  416, 
443.  5«>i  558.  581,  615,  640;  Paris,  54, 
136,  334,  442,  559. 

Leucxmia,  301. 

Leucorrhoea,  52J. 

Lewis,  Dr.  Daniel,  endorsed  diplomas  of  the 
United  States  Medical  College,  249. 

Lichen,  ruber  planus,  133. 

Life,  value  of  human,  644. 

Lime,  muriate  of,  288. 

Lincoln,  Dr.  R.  P.,  naso-pharyngeal  fibro- 
sarcoma, 455,  469. 

Lipoma,  of  the  arachnoid,  707;  of  the 
neck,  47. 

Listerism,  277  ;  and  craniotomy,  493,  643. 

Lithotrity,  extraordinary,  545. 

Liver,  abscess  of,  580  ;  adenoma  of,  706 ; 
affections  of,  in  syphilis,  544 ;  anomalies 
of,  50 ;  cirrhosis  of,  697 ;  hydatid  cyst 

of,  375. 

Localization,  central,  232,  342,  458,  536. 

Locomotor  ataxia,  265. 

London  Pathological  Society,  notice  of 
transactions,  20. 

Loomis,  Dr.  Alfred  L.,  book  notice,  412 ; 
Professor  Alfred  ll,  on  Colorado  cli- 
mate, 526. 

Lovage,  42a 

Lung,  calcareous  concretions  of,  bacilli  in, 
6S1 ;  hernia  of,  489  ;  sarcoma  of,  441. 

Lupus,  359;  salicylic  acid  in,  541. 

|M 

McCoy,  Dr.  George  T.,  opium  in  mitral  in- 
sufficiency, 585. 

Mackenzie,  Dr.  John  N. ,  hay-fever,  59 ;  hay 
asthma,  427. 

McLean,  Dr.  L«roy,  oesophagotomy,  281. 

Mackenzie,  Dr.  Morell,  hay  fever,  225. 

Madness  and  crime,  547. 

Major,  Dr.  George  W.,  buccal  breathing,  565. 

Malaria,  and  osteopathics,  266  ;  as  a  defence 
in  a  suit  for  rent,  318 ;  natural  produc- 
tion of,  197 ;  pernicious,  262 ;  prophy- 
laxis of,  208 ;  the  germ  theory  of,  597. 

Male,  hysteria  in,  346. 

Malpractice,  suicide  of  a  phjrsician  accused 

°^'7i3-  .       .     ^ 

Mammary  atrophy,  10 ;  tumors,  acatnx  after 

removal,  12. 
Mammer,  Dr.  Ernest,  item,  601. 
Manaca,  in  rheumatism,  31. 
Mania,  acute,  at  the  menstrual  period,  347. 
Manton,  Dr.  W.  P.,  notice  of  book  by,  2a 
Marsh,    Dr.  £.  J.,  period  of  greatest  risk 

from  consumption,  194. 
Marshal],  Dr.  John  S.,  "  dead  teeth  in  jaws," 

445- 
Marvin,  Dr.,  280. 

Mastoid,  indications  for  opening,  105. 
Materia  medica,  modem  progress  of,  573. 
Maternal  impression,  140,  225. 
Maxilla,  inferior,  fracture  of,  405. 
Measles,  German,  515. 
Medical  advertising,  490. 
Medical  charity,  abuse  of,  352 ;  abuse  of  in 

the  South,  109. 
Medical  chemistry,  140. 
Medical  department  during  the  Revolution, 

447- 
Medical  education  abroad,  494. 
Medical  education  and  practice,  546. 
Medical  journals,  German,  71. 
Medical  manners,  ancient  and  modem,  348. 
Medical  practice  in  Missouri,  570. 
Medical  rhymes,  547. 
Medical  Society  of  Berlin,  78,  133. 
Medical  Society  of  the  County  of  New  York, 

363»  495»  607,  715 ;  committees,  608. 
Medical  Society  of  Virginia,  323. 
Medical  students,  fewer,  713. 
Medicine,  and  medical  men  in  Denmark,  27  ; 

practice  of,  in  Russia,  717. 


Medico-Legal  Science  in  New]|York  City, 
712. 

Meier,  Dr.  G.  C.  H.,  electrolysis  in  strict- 
ures, 195. 

Melanaemia,  291. 

Meningitis,  simple  and  tubercular,  37 ;  tu- 
bercular, 48,  49,  358,  699. 

Menopaue,  cardiopathy,  347. 

Menstrual  period,  acute  mania  at  the,  347. 

Menstruation,  297  ;  condition  of  ovaries  in, 
293  ;  in  animals,  588  ;  the  wave  theory, 

318. 
Mercury,  bichloride,   solution   of,    168 ;  in 
the  urine,  405;  tannicum  oxydulatum, 

84. 

Metaplasia,  Virchow's  address,  294. 

Methyline,  bichloride,  death  from  use  of,  75. 

Metritis,  chronic,  134. 

Michigan  State  Medical  Society,  21. 

Microcephalus,  522. 

Midwifery,  antiseptic,  372. 

Midwives,  212. 

Migraine,  in  tabes,  597  ;•  prophylaxis  of,  <55. 

Milk  of  pregnant  cows  unfit  for  infants,  601  ; 
peptonized,  80,  364,  447;  peptonized, 
objections  to,  363. 

Millard,  Dr.  H.  B.,  prevalence  of  consump- 
tion at  different  ages  of  life,  527. 

Minor,  Dr.  James  ll,  cysticercus  in  the 
vitreous,  703  ;  hydrochlorate  of  co- 
caine, 439. 

Miryachit,  601. 

Mitchell,  Dr.  S.  Weir,  book  notice,  299. 

Moore,  Dr.  A.  M. ,  yellow  fever  on  the  U.  S. 
steamship  Portsmouth,  7. 

Moore,  Dr.  William  O.,  coca  leaf  and  its 
alkaloid,  5 10 ;  hydrochlorate  of  cocaine, 

438. 

Morphia,  in  cardiac  disease,  401. 

Morphinism,  and  pregnancy,  ii  ;  detected 
through  examination  of  the  urine,  685. 

Mouth,  hygiene  of,  in  the  new-bom,  377. 

Mouth-breathuig,  565. 

Mulhane,  Dr.  John  D.,  112. 

Mullen  leaves  in  phthisis,  319.! 

Mumps,  as  a  cause  of  sudden  deafness,  517. 

Mund6,  Dr.  Paul  F.,  tubal  pregnancy  treated 
with  galvanism,  337. 

Murmur,  encephalic  bellows  in  children,  403. 

Murmurs,  cardiac,  ii.}. 

Murray,  Dr.  R. ,  244. 

Muscle,  rupture  of,  simulating  abscess,  682 ; 
striated,  histology  of,  358. 

Muscles,  embolic  infarction  of,  291 ;  inter- 
costal, action  of,  38. 

Musk,  223. 

Myasis,  347. 

Myocaiditis,  chronic  fibrous,  5a 

Myomata,  uterine,  329. 

Myxoedema,  231,  302,  61 5. | 

Myxofibroma,  at  the  basis  cranii,  and  its  ef- 
fect upon  vision  and  hearing,  106. 

N 

Naphthaline,  in  diarrhoea  and  C3rstitis,  597. 

Naphthol,  in  scabies,  403. 

Needle,  a  new,  for  continuous  or  interrupted 

suture,  419 ;  the  vagaries  of  a,  251. 
N^roes,  why  they  are  black,  431. 
Nelson,  Dr.  C.  E.,  **dead   teeth  in  jaws," 

445. 
Nephrectomy,    165  ;   for  calculous  pyelitis, 

569 ;  in  infants,  682. 
Nephritis,  chronic  parenchymatous,  179. 
Nervous  diseases,  disturbances  of  the  urine 

in.  375. 
Nervous  exhaustion,  307. 
Nervous  impression,  69. 
Nervous  origin    of  some  disorders  of  the 

alimentary  canal,  497. 
Nerves,  reunion  of  divided,  97. 
Neuralgia,  epileptiform,   237  ;  facial,  368 ; 

syphilitic,  12;  tubercular,  39. 
Neurasthenia,   relation  of,  to  concussion  of 

the  spine,  617.  \ 
Neurectomy,  368. 
Neuroses,  cardiac,  86. 
Newcomb,  Dr.  J.  E.,  hospital  report,  263. 
New  York  Academy  of  Medicine,  415,  471, 

556,    612,   665,    711,    714;   section  in 

obstetrics,  693. 
New  York  Eye  and  Ear  Infirmary,  374. 


New  York  Hospital,  264. 

New  York  Neurological  Society,  497,  614. 

New  York  Pathological  Society,  47,  X 

441,  469.  5S2i  670, 697;  noticeof  tt^ 

actions,  20. 
New  York  State  Medical  Association  to* 

570,  572.  "^ 

New  York  State  Medical  Society,  465. 
Nicotinism,  acute,  376. 
Nipple,  Paget's  disease  of,  153. 
Nolan,  Dr.  E.  M.,  Florida  as  a  health  r. 

sort,  502. 
Nomenclature,  in  obstetrics,  330. 
North,  Dr.  N.  L.,  the  untrustworthintB  of 

fluid  extracts,  92. 
Northwestern  Medical  and  Surgical  Society, 

499.  637. 
Nose,  the  relation  between  diseases  of,  od 

nervous  afiiections,  235. 
Noyes,  Dr.  H.  D.,  correspondence,  417. 
Nutrition,  disorders  of,  related  with  affec- 
tions of  the  nervous  sjrstem,  203,  226. 
Nux  vomica  as  a  galactagogue,  82. 


Obesity  and  the  sexual  function,  279;  pt. 

thology  of,  183. 
Obstmction,  intestinal,  470. 
CBsophagotomy,  95,  281. 
CEsophagus,  stricture  of,  95,  278,  543. 
Officers  of  the  Army,  shall  they  engage  it 

private  practice?  194. 
Ohio  State  Sanitary  Association,  7x3. 
Oliver,  Dr.  N.  E. ,  peptonized  miUc,  363. 
Oliver,  Dr.  N.  E.,  removal  of  benign  tinion 

without  mutilation,  139. 
Omphalo-mesenteric  remains,  235. 
Ophthalmia,  contagious,  in  asylums  of  Nev 

York  City,  496 ;  gononrfaceal,  iodofom 

in»  376;   jequirity,    596;   ncomtonoi, 

358;  phlyctenular,  m. 
Ophthalmology,  light  sense  in,  387. 
Opii  acetum,  139. 
Opium,  as  a  heart  tonic,  585. 
Opium-poisoning,  nitrite  of  amyl  in,  13. 
Opium-smoking,  as  a  therapeutic  meiare, 

317 ;  danger  of,  as  a  therapeutic  mcu- 

ure,  501. 
Orbit,  rare  tumor  of,  13. 
Orchitis,  malarial,  347. 
Ord,  Dr.  William  M.,  address  in  me&iae, 

203,  226. 
Osteopathics,  and  malaria,  266. 
Osteotomy,  for  genu-vaigum,  276. 
Osteomyelitis,  706. 
Otis,  Dr.  F.  N.,  large   doses  of  potassia 

iodide  in  syphUis,  641. 
Otitis  media,   acute,  atropine  in,  517;  diy 

treatment,  21  ;  suppurative,  106. 
Othematoma,  4,  121. 
Otoscope,  new  electric,  616. 
Ovaries,  condition  of,  during  menstraatioa, 

293- 
Ovariotomy,  and  Listerism,  493,  643 ;  en? 

performance  of,  331  ;    in  Rome,  688; 

in  the  corpulent,  251. 
Oxygen  and  its  congeners,  283,  313. 
Ozena,  403. 
Ozone,  in  rheumatism,  601. 


Pachymeningitis,  hemorrhagica,  670. 

Paracentesis  thoracis,  574. 

Paraldehyde,  as  a  hypnotic,  317 ;  in  dE&iaai 

tremens,  39. 
Paralysis,  from  use  of  crutches,  599 ;  inin- 

tile,  resection  of  muscles  in,  diS;  paodo- 

bulbar,  487,  498;    reflex,  12;  witbotf 

anaesthesia,  3& 
Paraphimosis,  403. 
Paraplegia,  acute  painful,  377,  519;  nriniiyi 

230. 
Page,  Dr.  A.  C,  antiseptic  midwifov,  37* 
Page,  Dr.  R.  C.  M.,  lead-p9isoning,  621- 
Paget^s  disease  of  the  nipple,  153. 
Palato-graphy,  380. 
Palmer,  Dr.  J.  G.,  chronic  hydrocephaH 

705-  .    , 

Pancreas,  cancer  of,  532,  593;    cirrhossff 
the,  505. 


December  27,  1884.] 


INDEX. 


723 


Panam,  Dr.  P.  L.,  address  at  International 

Medical  Congress,  203. 
Paris  Academy  of  Medicine,  51. 
Park,  Dr.   G.   C,  extra-uterine  pregnancy, 

224- 

I>arlc,  Dr.  Roswell,  electric  otoscope,  616. 

Parker,  Dr.  J.  B.,  acute  iodism,  587. 

Parker,  Willard,  M.D.,  LL.D.,  in  memo- 
riam,  189. 

Parker,  Dr.  William  S.,  quacking  sounds  in 
the  ear,  139. 

Parker,  Dr.  w.  Thornton,  181  ;  tube  for  in- 
jecting and  measuring  the  uterus,  305. 

Parks,  Dr.  N.  O.  D.,  malarial  gastralgia,  288. 

Parmenter,  Dr.  John,  local  use  of  ether  in 
the  bladder,  25. 

Partridge,  Dr.  Edward  L.,  notice  of  transla- 
tion by,  494. 

Patella,  fractured,  265. 

Patellar  tendon  reflex,  1 1 ;  and  ankle  clonus, 
403.  ^ 

Pathology,  gastnc,  630. 

Paul,  Dr.  Constantine,  notice  of  book  by, 
19. 

Peck,  Dr.  Edward  S.,  astringents  and  caus- 
tics in  ophthalmic  practice,  482. 

Pellctierinc,  81. 

Penis,  fracture  of,  549. 

Pension,  psycho-pathology  of  application  for, 
140. 

Pepsin,  272. 

Peptones,  195. 

Peptonized  milk,  138. 

Percy,  Dr.  Samuel  R.,  cocaine,  55a 

Perimeter,  M.  Hardy's,  389. 

Perimetritis,  333. 

Periostitis,  rheumatismal,  598. 

Periproctitis,  simulating  typnoid  fever,  J77. 

Peritonitis,  from  diseases  of  the  vermiform 
appendix,  600  ;  tubercular,  47. 

Perry,  Dr.  A.  W.,  the  abuse  of  tonics,  718. 

Peters,  Dr.  John  C,  muriate  of  lime,  288'; 
Warburg's  tincture,  63. 

Pharmacology,  663. 

Philadelphia  Hospital,  179. 

Phlebitis  and  rheumatism,  I2.[ 

Phosphorus,  action  of,  on  the  foeins,  293; 
dosage  of,  380. 

Phthisis,  death-rate  of,  69;  in  the  light  of 
recent  discoveries,  670;  mullen-leaves 
ii^t  3^9  f  ^c^  remedy  for,  9 ;  old  catar- 
rhal, 699;  transmissibility  of,  193; 
treated  by  overfeeding,  66. 

Phymosis,  without  operation,  599. 

Physician,  the  oldest,  in  the  State,  672. 

Physicians,  holiday  seasons  for,  348 ;  visit- 
ing list,  692. 

Phjrsiology,  address  in,  113;  every-day,  588; 
temperance,  42. 

"  Physyke"  a  good  general  rule,  27. 

Pinkney,  Dr.  Howard,  natural  sidphur  wa- 
fers, 539. 

Pitchfork,  injury  from,  429. 

"Pidgen"  English,  72. 

Placenta,  adherent,  27. 

PUcenta  pnevia,  89. 

Plaster-of-Paris  jackets,  428 ;  substitutes  for, 

705. 

Pleurisy,  with  effusion,  electricity  in,  476. 

Pleuritic  effusions,  the  induced  current  in, 
266 ;  exudations,  the  tuning-fork  in  the 
diagnosis  of,  11. 

Pleuro-pneumonia,  271. 

Pneumonia,  and  cold  bath,  543 ;  acute,  and 
tuberculosis,  430 ;  acute  lobar,  434  ; 
calomel  in  the  treatment  of,  683 ; 
chill  in  etiology  of,  13  ;  chronic,  in  the 
light  of  recent  discoveries,  679 ;  cocci 
of,  and  organumis  of  salivary  septicaemia, 
140;  iodide  of  potassium  in,  13;  sub- 
acute, 304;  subclavicular  tympanitic 
resonance  in,  266;  tuberculous  croup- 
ous,  399. 

Pneumonotomy,  223. 

Pneumotherapy,  application  to  diseases  of 
the  heart,  124. 

Podophyllum,  poisoning  by,  345. 

Poison  labels,  319. 

Poisons,  chemical, ^formed  in  the  [^ intestinal 
canal,  683. 

Polk,  Dr.  W.  M.,  cocaine  as  a]j1ocal}  anaes- 
thetic in  gynecology,  489. 

Polycoria,  164. 


Polypi,  nasal,  189. 

Polypus,  naso-pharyngeal,  387. 

Polyuria  in  typhoid  fever,  265. 

Poore,  Dr.  Charles  T.,  book  notice,  356. 

Post-mortem  specimens,  temporary  preserva- 
tion of,  560. 

Potash,  bichromate  of,  antiseptic  properties 
of,  II. 

Potassium,  iodide  of,  492,  584;  in  pneu- 
monia, 13 ;  in  S3rphilitic  deafness,  257  ; 
large  doses,  688 ;  large  doses  in  sjrphllis, 
641. 

Potts*  disease,  13. 

Practitioners'  Society  of  New  York,  361, 
413,  609. 

Prayer,  the  therapeutic  effect  of^  713. 

Pregnancy,  and  morphinism,  1 1 ;  diagnoas 
o^  330;  extra-uterine,  362;  383,466, 
577 ;  false,  69 ;  morphine  in  vomiting 
of,  237 ;  multiple,  26 ;  protracted, 
584 ;  tubaL  96,  445 ;  tubal  arrested  by 
galvanism,  392  ;  tubal,  galvanism  in, 
337  ;  vomiting  of,  624,  664. 

Prendergast,  Dr.  P.  J,,  continuous  suture, 
616. 

Prepuce,  dilatation  of,  599. 

Presbyopia,  and  accommodation,  586. 

Prostate,  enlarged,  10,  293;  hypertrophy, 
treated  without  catheterism,  22. 

Pruritus,  oleate  of  chloral  for,  543. 

Pseudarthrosis,  292. 

Psoriasis,  431. 

Pupils,  the,  in  epileptics,  39. 

Puerperal  infection  of  the  male,  707. 

Purpura,  cachectic,  264 ;  varieties  of,  517. 

Pustule,  malignant,  542. 

Pyelitis,  calculous,  nephrectomy  for,  569. 

Pyelo-nephritis,  697. 


Quarantine,  in  cholera,  570. 

Quebracho,  alkaloids  of,  599 

Quinan,  Dr.  John  R. ,  notice  of  book  by,  2a 

Quinine,  amorphous  borate,  X12;  contra-in- 
dications  m  the  use  of,  66 ;  hydrobro- 
mate  of,  222 ;  hypodermics  of,  in  differ- 
ential diagnosis,  265.) 


Rabies,  92 ;  in  birds,  96. 

Rachitis,  139. 

Rape,  rights  of  defendant,  279. 

Rattlesnake-poisoning,  137. 

Rectum,  a  receptacle  for  excremental  matter, 
309 ;  imperforate,  97,  541 ;  malignant 
affections,  operative  treatment  of,  274. 

Redfem,  Dr.  Peter,  address  in  physiology, 

"3- 

Refraction,  new  method  of  determining,  388. 

Reese,  Dr.  John  J.,  book  notice,  299. 

Resorcin,  antidote  of,  683  ;  for  whooping- 
cough,  551  ;  in  laryngeal  affections,  543. 

Respiration,  effect  on,  produced  by  com- 
pressed air,  122. 

Respiratory  medicaments,  122. 

Reynolds,  Dr.  Walter  B.,  poisoning  by  po- 
dophyllum, 345. 

Rheumatism,  and  phlebitis,  12;  carbolic 
acid  in,  10 ;  gonorrhoeal,  229 ;  manaca 
in,  31 ;  ozone  in,  601. 

Rhinelander,  the  case  of,  520. 

Richmond,  French  compliment  for,  27. 

Rickets,  357. 

Riley,  Dr.  F.  C,  failures  with  cocaine,  658. 

Riley,  Henry  A.,  Esq.,  the  laws  of  dissec- 
tion, 486 ;  the  law  regulating  the  com- 
pensation of  physicians,  626. 

Roane,  Dr.  James,  veratrum  viride,  586. 

Roberts,  Dr.  F.  T.,  book  notice,  299. 

Robbins,  Dr.  C.  W.,  intravesical  injections 
for  cystitis,  704. 

Rockwell,  Dr.  A.  D. ,  notice  of  book  edited 
by,  300;  the  induction  coil,  513,  558, 
585 ;  tubal  pregnancy  arrested  by  ^- 
vanism,  392. 

Rodenstein,  Dr.  L.  A.,  305. 

Rogers,  Dr.  Robert*  E.,  obituary,  30a 

Roosa,  Dr.  D.  B.  St.  John,  correspondence, 
391 ;  cocaine,  463.  '"'    "^ 


Roosevelt  hospital,  263. 

Rose-cold,  420. 

Rotation  of  the  forearm,  599. 

Rothacker,  Dr.  W.  A.,  notice  of  book  by, 

692. 
Rowe,  Dr.  Frank  H.,  tape- worm,  56. 
Royal  College  of  Surgeons,  81. 


Sarcoma,  generalized,  431 ;  of  the  mediasti- 
num and  lung,  441. 

Saundby,  Dr.  Robert,  examiners  at  the 
Royal  College  of  Surgeons,  England, 
8i. 

Scabies,  naphthol  in,  403. 

Sciatica,  265 ;  treated  by  congelation,  347. 

Sclerosis,  following  infectious  diseases,  293 ; 
of  the  coronary  arteries,  682. 

Scrofula  and  tuberculosis,  376. 

Scrotum,  a  compressor  for,  529. 

Scudder,  Dr.  H.   Martyn,  cholera  in  India, 

255. 

S^e,  Professor  Germain,  respiratory  medica- 
ments, 122. 

Seguin,  Dr.  E.  C,  notice  of  book  by,  21, 

Semple,  Dr.  Armand,  notice  of  book  by,  19. 

Septicaemia,  masked,  375 ;  puerperal,  292. 

Sero-sublimate,  548. 

Serpent-poisoning,  408. 

Sewers,  ventilation  of,  49J. 

Sexton,  Dr.  Samuel,  deadf  teeth  in  the  jaws, 
525  ;  defective  hearing  in  the  public 
schools,  675;  diseases  of  the  external 
ear,"3,ii9,  149,  173,  374, 

Shafer,  Dr.  J.  P.,  renal  calculi,  587. 

Shawl-pin,  swallowing  of,  695. 

Sheardown,  Dr.  T.  W.,  the  abuse  of  medi- 
cal charity  in  the  South,  109  ;  the  treat- 
ment of  dyspepsia  by  hot  water,  563. 

Shears,  Dr.  C.  H.,  cocaine  in  dentistry,  657. 

Shillock,  Dr.  P.  T.,  intestinal  obstruction, 
196. 

Shirk,  Dr.  J.  K.,  notice  of  book  by,  46. 

Shrady,  Dr.  George  F.,  strangulated  hernia* 

.     591.     . 

Siamese  twms,  39. 

Sickness,  the  cost  of,  586. 

Silver,  iodide  of,  644 ;  nitrate,  in  adenitis, 
375  ;  nitrate  of,  injections  of,  in  the 
blaidder,  501. 

Simon,  Dr.  W. ,  book  notice,  524. 

Slzer,  Dr.  A.  B.  de  S.,  congenital  hemor- 
rhoids, 584. 

Skene,  Dr.  A.  J.  C,  book  notice,  356. 

Skin,  ethics  of,  167 ;  specific  sensibility  of 
the,  359 ;  treatment  of  diseases  of,  at 
Vienna,  532. 

Skull,  osteitis  of,  386. 

Sleep,  706. 

Small-pox,  honey  for,  293;  susceptibility  to, 
181. 

Smiley,  Dr.  D.  B.,  correspondence,  448. 

Smith,  Dr.  Andrew  H.,  catheterization,  456; 
the  tolerance  of  small  doses  of  corrosive 
sublimate,  312. 

Smith,  Dr.  Eugene,  cocaine  in  indectomy. 

Smith,   Dr.    F.    W.,  the  swallowing  of  a 
shawl-pin,  695. 
658. 

Smith,  Dr.  H.  Lyle,  tape-worm,  82. 

Smythe,  Dr.  G.  C,  pelletierine  for  tape- 
worm, 81. 

Smith,  Dr.   J.  Lewis^  peptonized  milk,  80^ 

138. 

Smith,  Dr.  Samuel  W.,  plaster-of- Paris  jack- 
ets. 428. 

Snake-bites,  404. 

Soda,  bicarb.,  in  tonsillitis,  153. 

Sodium  iodide  instead  of  potassiumjjiodide, 
112. 

Sohlin,  Dr.  Charles,  jequirity,  562. 

Somnambulism,  partial,  247. 

Soul-blindness,  536. 

SpermatophobA,  238. 

Spermatorrhoea,  238. 

Sperry,  Dr.  S.  B.,  hay-fever  in  an  infant, 

503- 

Spina-bifida,  injections  in,  292. 

Spine,  concussion  of,  617,  634;  disease  and 
curvatures  of,  701 ;  progno«s  of  curva- 
tures of  the,  683. 

Spiraea  ulmaria,  in  enlarged  prostate,  lo. 


724 


INDEX. 


[December  27,  1884, 


Spitzka,  Dr.  £.  C,  anomaly  of  a  vertebra, 
680 ;  gross  anatomy  of  the  fourth  ventri- 
cle, 249  ;  hippocampus  vs.  hypocampa, 
335  ;  morphological  status  of  the  cere- 
beUum,  1 1 1  ;  the  anatomy  of  the  lem- 
niscus, 393,  421,  449,  477. 

Spleen,  extirpation  of,  84,  166. 

Splenectomy,  37. 

Splints,  flexed,  716. 

Sponge,  artificial,  9;  Mr.  Gamgee's,  108. 

Sprains,  112. 

Spray-producer,  306. 

Squint,  atropine  in  convergent,  389. 

St.  Catherine's  Hospital  Report,  402. 

St.  Luke's  Hospital,  medical  histories  of, 
446. 

Stammering,  601. 

Stanton,  Dr.  John  G.,  correspondence,  279 ; 
shall  officers  in  the  army  engage  in  pri- 
vate practice?  83. 

Sternberg,  Dr.  George  M.,  book  notice, 
495  ;  disease  germs,  451 ;  pneumonia 
cocci  and  organisms  of  salivary  septi- 
csemia,  140. 

Stevens,  Dr.  B.  N.,  correspondence,  448. 

Stewart,  Dr.  Jacob  H.,  obituary,  300. 

Stickler,  Dr.  J.  W. ,  cocaine  in  general  sur- 
gery, 657 ;  sea-voyage  and  chronic 
diarrhoea,  512;  traumatic  tetanus,  288. 

Stimson,  Dr.  J>wis  A.,  laparomyotomy, 
370. 

Stockard,|Dr.  C.  C. ,  fibro-cyst  of  the  uterus, 

177. 

Stomach,  cancer  of,  385,  469,  593,  686 ;  dila- 
tation of,  431 ;  dilatation  of,  in  children, 
489 ;  gun-shot  wound  of,  224 ;  irriga- 
tion of,  540 ;  miliary  aneurisms  of,  97, 
293  ;  pathology  of,  630 ;  swashing  sound 
in,  as  a  symptom,  264. 

Stomach-pump,  305. 

Stomach-tube,  death  from  the  introduction 

of,  504. 

Stone,  Dr.  R.  M. ,  glass  wound,  456 ;  gun- 
shot wound  of  the  stomach,  224. 

Strabismus,  latent,  389. 

Strsunonium,  leaves  of,  for  painful  joint  af- 
fections, 316. 

Strecter,  Dr.  F.  B.,  420. 

Streeter,  Dr.  H.  W.,  electrolysis  in  strict- 
ure, 94,  250. 

Stricture,  urethral,  673;  treated  by  mas- 
sage, 96  ;  electrolysis  in,  94,  250. 

Strictures,  of  the  oesophagus,  278,  543. 

Sugar  as  a  food,  139  ;  bismuth-test  for,  491. 

Summer  complaint,  87. 

Summer  vacations,  16. 

Supra-renal  capsule,  545. 

Surgeons,  army,  shall  they  practise  outside 
of  their  posts  ?  83. 

Surgery,  pulmonary,  641. 

Surgical  aid  to  children,  373. 

Surgical  Society  of  Paris,  165,  386. 

Suture,  continuous,  616. 

Symptoms,  value  of  certain,  in  diagnosis  of 
diseases  of  children,  67. 

Syphilide,  acute  phagedenic  pustular,  441. 

Syphilis  and  cholera,  385  ;  and  mercury  and 
cholera,  447  ;  bacillus  of,  687  ;  inherited, 
affections  of  the  liver  in,  544 ;  initial 
sclerosis,  excision  of,  360 ;  treatment  by 
inunction,  360. 


Tabes,  migraine  in,  597. 
Tait,  Dr.  Lawson,  643. 
Tape-worm,  56,  81,  232,  251,  308  ;  treaiccl 

with  chloroform,  112,  429,  475,  601. 
Tattoo-marks,  removal  of,  598. 
Tauszky,  Dr.  Rudolph,  correspondence,  418. 
Taylor,  Dr.  W.  H.,  rectal  etherization,  346. 
Teeth,  dead,  in  the  jaws,  379,  444,  473,  521, 

525.  5641  6S9 ;  loosening  of,  432. 
Teller,  Dr.  S.,  fracture  of  the  clavicle,  527. 
Tendon,  reflex,  patellar,  11. 
Testicles,  superntmierary,  196* 


Test-papers,  urinary,  140. 

Tetanus,  34 ;  following  Heaton's  method 
for  the  cure  of  hernia,  64;  infantum, 
631  ;  traumatic,  288. 

Thallin,  687. 

Thayer,  Dr.  C.  C,  hepatic  albuminuria,  124. 

Theme,  491. 

Therapeutical  Society  of  Parb,  53,  j86. 

Therapeutics,  artificial  hypnotism  m,  632 ; 
dogmatic,  588;  heat  and  cold  in,  397, 
413  ;  medicinal  and  non-medicinal,  579. 

Thermometry,  aural,  489. 

Therpyline,  hydrate  of,  545. 

Things  to  try,  420. 

Thompson,  Dr.  John  H.,  chloroform  and 
tape- worm,  601. 

Thorax,  funnel-shaped,  30. 

Throat,  an  instrument  (ox  pencilling  chil- 
dren's, 377 ;  typhoid  ulcerations  of  the, 

405. 
Thumb,  dislocation  of  the  first  phalanx,  578. 
Thymol,  in  treatment  of  cholera,  296. 
Thyroid  gland,  function  of,  266 ;    removal 

of,  375. 

Tibia,  ununited  fracture,  205. 

Toe-nail,  ingrowing,  96. 

Tongue,  convulsions  of,  509 ;  gummy  tumor 
of,  403. 

Tonics,  the  abuse  of,  718. 

Tonsils,  hypertrophied,  598 ;  the  three,  365  ; 
their  structure  and  function,  415 ;  tu- 
berculosis of,  292. 

Tonsillitis,  153. 

Tonsillitome,  Marconi's,  616. 

Tonsillotomy,  597. 

Tosswill,  Dr.  Louis  H.,  notice  of  book  by. 

Tooth,  death  following  extraction  of,  97  ; 
replantation  of,  84. 

Tracheotomy,  in  croup  and  diphtheria,  534, 
643*  64s*  665,  700. 

Trachoma,  in  the  negro,  704. 

Trance,  706. 

Transfusion,  572. 

Transplantation,  without  pedicle,  161J 

Trichinosis,  14a 

Trichorrhexis  nodosa,  683. 

Trineural  fasciculus,  450. 

Traumatism  and  tuberculosis,  376. 

Tubercle  bacilli  in  the  non- tuberculous,  138. 

Tubercles,  of  the  breast,  39. 

Tuberculosis,  302,  317  ;  and  acute  pneumo- 
nia, 430;  and  joint  disease,  578;  and 
traumatism,  376;  and  scrofula,  376; 
general,  189  ;  miliary  in  the  light  of  re- 
cent discoveries,  679 ;  of  the  eye,  681. 

Tumor,  bony,  of  the  brain,  707  ;  gummy,  of 
the  tongue,  403. 

Tumors,  removal  of  benign,  139. 

Tuning-fork,  in  the  diagnosis  of  pleuritic  ex- 
udations, II. 

Tyson,  Dr.  James,  chronic  parenchymatous 
nephritis,  179. 


U 


Uhler,  Dr.  J.  R.,  cocaine  in  general  surgery, 
657. 

Ulcer,  of  the  leg,  681. 

Ulna,  luxation  of,  with  Colles'  fracture,  279. 

Unchastity,  531. 

Ureter,  closure  of,  52. 

Urethra,  stricture  of,  treated  by  massage,  96. 

Ursemia,  246  ;  and  urea,  698 ; 

Urea,  69. 

Urethritis,  gonorrhoeal,  673. 

Urine,  albuminosc  or  peptone  in,  350;  am- 
moniacal,  12;  detection  of  morphinism 
by  examination  of,  685 ;  disturbance  of, 
in  nervous  diseases,  375 ;  mercury  in, 
405. 

Uterus,  anteflexion  of,  693  ;  cancerous  affec- 
tions of,  265;  fibro-cyst  of,  177,  470; 
inversion  of,  382;  latero-positions  of, 
332 ;  tube  for  measuring,  305. 


Vaccination,  173 ;  insusccptibiUty  to.  661^ 
susceptibility  to,  181.  ^' 

Valentine,  Dr.  Samuel  M.,  notice  of  detd 
of,  436.  ^^ 

Valerian.  4»:oction,  in  contusions,  508. 

Valvulitis,  cardiac,  29. 

Variola  and  varicella,  707. 

Venesection,  in  puerperal  convulsions,  576 

Veratria,  in  muscular  tremors,  272. 

Veratrum  viride  as  a  prophylactic  agaiast 
peritonitis  after  surgical  operations,  586- 
m  tetanus,  34.  '     ' 

Vermiform  appendix,  peritonitis  from,  6oa|| 

Vidal,  Dr.  Etienne  C,  correspondence,  474 

Vinegar,  in  post-partum  hemorrhage,  6(5. 

Vision,  cerebral  centres  for,  342 ;  improved 
by  hyperbolic  lenses,  163. 

Vitreous,  cysticercus  in,  703 ;  remo?aloffor. 
eign  bodies  from,  164* 

Vivisection,  46,, 

Vomiting,  in  children,  38 ;  in  pregnaac^,  62/ 

W 

Wackerhagen,  Dr.  G.,  a  new  needle,  419. 
Wallian,  Dr.  Samuel  S.,  oxygen  as  a  reD«> 

dial  agent,  283,  313. 
Warburg's  tincture,  63. 
Ward,  Dr.  E.  B.,  415. 
Warts,  432. 
Water,  hot,  therapeutical  effects  on  nervov 

diseases,  471. 
Waters,  natural  sulphur,  539. 
Weber,  Dr.  Leonard,  nervous  origin  of  som 

disorders  of  the  alimentary  canal, 

497, 
Webster,  Dr.  David,  enucleation  of  1  s(i 

phylomatous  eyeball,  93. 
Weigert's  method  of  staining  the  bnm  and 

spinal  cord,  628. 
Weisse,  Dr.    Faneuil  D.,  pain,  in  stnctut 

after  gonorrhoeal  urethritis,  673. 
Weld,  Dr.  G.  W.,  cocaine  in  dentistry,  657, 
Wendt,    Dr.    E.  C,  cholera  and  bactai- 

oscopy,    589  ;    chronic  pneomonia  ind 

phthisis  in  the  light  of  recent  discover- 
ies, 679  ;  tuberculosis  and  acote  poa- 

monia,  43a 
Whiskey,  as  an  anaesthetic,  588. 
White,  Dr.  Leonard  D.,  448. 
Whitla,  Dr.  William,  notice  of  book  by,  ^. 
Whooping-cough,  resorcin  for,  551. 
Wilfert,  Dr.  H.,  tape-worm,  82. 
Wilder,  Dr.  Burt  G.,  themorphologiola. 

tus  of  the  cerebellum,  249. 
Williamson,  Dr.  C.  H.,  yellow  fever  at  S* 

ama,  509. 
Wilson,  Dr.  F.  M.,  cocaine  m  milJfS8^ 

gery,  582. 
Winters,    Dr.    Joseph   E.,   trachettoajii 

diphtheritic  croup,  645,  665. 
Wise,  Dr.  A.  T.  Tucker,  book  notice,  # 
Woakes,  Dr.  Edward,  notice  of  book  by,  i^ 
Woodward,  J.  J.,  M.D.,  obituary,  215,14^ 
Wound,  abdominal,  415. 
Wounds,  antiseptic  treatment  of,  357. 
Wylie,  Dr.  W.  Gill,  vomiting  in  pregMKS 

624. 
Wyman,  Dr.  Hal  C,  stramonium  law  It 

painful  joint  aflFections,^3i6. 


Yellow  fever,  the aUeged  "vaccine'*  agsiit, 

712.  ' 

Yeo,  Dr.  Gerald  F.,  notice  of  maniiillifr 

495. 

Zenner,  Dr.  Philip, cerebral  localiatioii,??* 
342,458,  536;  the  centres  for  viaoi, 

Ziegler,  Dr.  Ernest,  notice  of  book  by,  ^ 


41.A32 

6      Date  Due       \ 

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«ry  BuTMM  Cat.  no.  11 S7 


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