The Canadian
iiORAGE
Medical
C^Ditorial ^taff:
W. H. B. AIKINS, M.D.
A. B. ATHERTON, MD J. FERGUSON, MD
J. H. BURNS, M.D. ALBERT A. MACDONALD, M.D
G. STERLING RYERSON, MD. ALLEN BAINES, M.D.
Review
Vol. II.
NOVEMBER, 1895
y- _
eV^ Lactopeptine
BiiA^feWlT THE BRITISH MEDICAL PRESS THINKS OF THEM.
& Medical
C_ •'* |Che composition of Lncto-
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the formula of Lactopeptine
Powder. We have proved its
digestive powers by observ-
ing its proteolytic action upon
egg albumen. Each Tablet
contains five grains of Lacto-
peptine, the uses and value
of which are obvious from the
formula."— taTice/, August
3rd, 1895.
"A most convenient form
for administering this valu-
able remedy. The Tablets
are small, soluble and per-
fectly agreeable in flavor.
We can highly recommend
this new form of Lactopep-
tine, and feel confident that it
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Medical Press and Circular,
August 7th, 1895.
"Everything that the sci-
ence of pharmacy can (lo for
the improvement of the
manufacture of pepsin, pan-
creatine and diastase has
been quietly applied to these
ferments as compound in Lac-
topeptine. "—Medical Times
and Hospital Gazette, Axigust
:5l8t, 1895.
Samples Sent Physician.s on Ai)i)l:cation.
■ This will be found the
most convenient form of ad-
ministering this most valu-
able medicine." —Edinburgh
Medical Journal. August.
1895.
" We have received samples
of Lactopeptine Tablets, a
convenient form of this un-
doubtedly valuable prepara-
tion."—Si'r»«'n.(/Aa>/t Medical
Revictr. August, 1895.
■"Lactopeptine Tablets are
small, soluble and agreeable
ill flavor. Lactopeptine Pow-
der is, as a mixture of diges-
tives, fully up to date."—
British Medical Journal,
August 17th, 1895.
" The-se Tablets will be
found very convenient, espe-
cially for tourists and travel-
lers, and are readily taken
by children as well as adults,
and, having given them an
extensive trial, we can say
with equally satisfactory re-
sults.— Medical Times and
Hospital Gazette, August
24th. 1895.
The New York Pharmacal Association
30 WELLINGTON ST. EAST, TORONTO.
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Illustrated Price List and further particulars on application to the
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63 King Street West, - TORONTO.
TELEPHONE 261 1.
WREYFORI) A:(0.
Proprietors.
I.-wiies" iJept. muier chari;e of
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The Toronto Nursing Home . .
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. . and Cottage Hospital
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References to any of the numerous medical men who have had patients under treatment in this
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LAKEHURST
SANITARIUM
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FOR 1I1K TRKATMB.NT OP
. INEBRIETY
(Habitual and Periodical)
MORPHINE, and other DRUG HABITS and NERVOUS DISEASES.
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C. A. McBRIDE, NIE).,
Medical Superintendent, OnWville
ADVERTISEMENTS.
CONTKNTS.
ORIGINAL COMMUNICATIONS. PAGE
Some Proposed Changes in the Militia Medi-
cal Service. ByW. Tobin. M.D.,F.R.C.S.G 153
CLINICAL NOTES.
Miiltilocular Ovarian Cystic Tumor. By
Dr. Albert A. Macdonald, Toronto 162
TRANSLATIONS.
The Doctorate and the Milita; y Law. By
Dr. Sprague, Stirling, Ont 16i
SOCIETY REPORTS.
Toronto Clinical Society 166
A Case of Abdominal Aneurism 167
Metrorrhagia Cured by 0\ aiiotoni.v 169
Toronto Medical Society— I)iphlluTiu in an
Infant — Suppurative Choki-ystitis 171
Atropia Poisoning 174
EDITORIALS.
Graveyard Insurance 176
Vaccination Against Diphtheria— The Doc-
torate and the Military Law— Death of
Mathieson 177
Retiring Allowances to Drs. .1. Ferguson,
W. W. Ogden and M. H. Aikins— Ontario
Medical Library As.;ociation — Western
Territorial Division Associ \tion of Toronto 178
EDITORIALS (Continued). PAGE
Why They see Snakes— Dr. Gowers' Ad-
dress to Medical Phonographers 179
Xew Treatment for Severe Vomiting-
Puerperal Con vulsions— Address on Medi-
cal Education 180
Medical PMucation— Military Medical Notes 181
BOCK NOTICES.
An Illustrated Monograph on Oxyhfiemo-
globin and Allied Prnducts. By F. E.
Stewart, M.D., Ph.G. and others 182
Green's Pathology and Morbid Anatomy.
By T. Henry Green, M.D. — Saunder's
American YearUook of Medicine and
Surgery. By George M. Gould, A.M.,
M.D ■ 183
A Treatise on the Nervous Diseases of
Children for Physicians and Students.
By B. Sachs, M.D. — Clinical Lectures on
Diseases of the Nervous System. By W.
R. Gowers. M.D., F.R.S 18*
PERSONALS 18»
MISCELLANEOUS.
The Morals of a Surgeon 186
Illegal Practitioners 187
Protonuclein ; Leucocytes and Nuclein. By
Thos. O. Summers, M.A., M.D., F.R.S.C.,
London 186
Tendon Grafting 198
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THE INEBRIATES^ HOME,
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. . . INCORPORATED 1866 . . .
A Hospital fur the Treatment of ALCOHOLISM :ind the OPIUM HABIT.
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Asxuitant Pkpsician : F. L. DOLBMARK, M.D.
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DR. CHARLES R. DICKSON
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DR. J. ALGERNON TEMPLE.
DR. ALBERT A MACDONALD.
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Private Hospital for the treatment of
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ADVERTISEMENTS.
DR. N/IEYERS
Desires to announce to the Profession that he has
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DUNCAN, FLOCKHART & CO.'S
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ADVERTISEMENTS.
Thomas Johnston, | Dispensing...
Cor. Church and Wellesley Streets. Vl/HcMlS 1
Special care given to the compounding of PhyKvciana' Prescriptions. : : :
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Kossin IJIoek,
TORONTO, ONT.
'T'HE undersigned begs to draw the attention of
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the only truss that works upon the proper prin-
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YOUR PATRONAGE INVITED.
B. LINDMAN,
Tkl. 1635. Prop.
St. Leon Springs Water
DR. SEVERIN LACHAPELLE, Editor-in-Chief of the Journal
cfHy<(u'/u\ in two well-written articles, recently published on the
virtues of the
CELEBRATEDJiT. LeON WaTER,
gives very careful analysis thereof, and he states the various diseases
for \vhich this water is positively efficacious ; amongst others Dys-
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ANALYSIS
Chloride of Sodium 677.4782 grains. Sulphate of Ijime
Potassium 13.til70 "
Lithium 1.6147
Barium 6<)99
Strontium ;')0"0
Calcium 3.3:K8
Magnesium
Iodide of Sodium
Bromide of Sodium ....
59.0(131)
.2479
.SIOS
,,, , 0694 grains.
Phosjihiite ot Soda 1G90 "
Bi-Carbonate of Lime . . 29.4405 "
Magnesia 82.1280
Iron 6«.i6
Alumina ,5,s:«)
yil't-ii ]".:«i94
IJeiisity l.((U8
I hereby certify that I have analyzed a sample of " .St. Leon Water," taken from the bulk
from the store cellars in Montreal, and 1 am able to contirm the geneal re-^ult of the analysis
published by Dr. T. .Sterrv Hunt, I<\R..S., published in the repon of the Geological Survey
1863; also the analysis ol Prof. C. F. Chandler, of Columbia College, New York made in 1876
(Signed) JOHN BAKER EDWARDS. Ph.D., D.C.S , F.C.S., aAd ex ProSo;
Chemistry and Public Analyst.
ADVERTISEMENTS.
FRESH (UNDRIED)
a
KOLA NUTS
DIRECT FROM AFRICA.
NOTWITHSTANDING the statements of certain conipetilors that the fresh Kola
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we are still receiving importations every month, and supplying samples of the fresh
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spring shipment. It is a very handsome lot indeed, and we shall be glad to supply
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which test was nia<le with fresh African Kola nuts and their preparation, Kolavin, 'J]
furnished by us. Ijt
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200
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The Doctor E.s:plains
- HOW T WAS DONE''
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It is a wonderful sustainer of nervo-muscular energy in propelling a
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W. N. ROBERTSON, M.D.
33 Erie St., Stratford, June 7, 1895.
P.S. — Maltine with Coca Wine is a wonderful heart-sustainer. — W. N. K.
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COMPOUND SYRUP OF THE HYPOPHOSPHITES
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ADVERTISEMENTS.
FLAVELL'S
ABDOMINAL SUPPORTER.
DIRECTIONS FOR MEASUREMENT.
Give exact ciiviiniferencc of body at K, L, yi
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Thread Elastic, each - S2 00
The Abdominal Supporter is used extensively
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Goods sent by mail upon receipt ol
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ADVERTISEMENTS.
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The following New Publications have just been received :
Senn's Principles of Surgery (New Edition) | A System of Legal Medicine. By Allan
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Parsley seed .... Grs. 30
Black Haw (bark of the
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Henbane leaves ... "6
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m^^wmmwmmmAms
THE
Caiiadian JVEedical I^evieW.
EDITORIAL STAFF:
\V. II. B. AIKINS, M.D.,
J'luisiciaii to Tuionto General Hospital.
A. B. ATHEKTOX, M.D., J. H. BURNS, M.D.,
Surgeon to General Hospital, Frederieton, N.B. Surgeon to St. John's Hospital for Women.
J. FERGUSON, M.D.,
Physician to Western Dispensary.
ALBERT A. MACDONALD, M.D., G. STERLING RYERSON, M.D.,
Oyncvcologist to Toronto General Hospital. Oculist and Aunst to Toronto General Hospital.
ALLEN BAINES, M.D.,
Physician to Hospital for Sick Children.
Vol. II.] TORONTO, NOVEMBER, 1895. No. 5
©rioinal Communications.
Some Proposed Changes in the Militia Medical Service.
BY W. TO BIN, F.R.C.S.G.,
Deputy Surgeon-General, Canadian Militia.
[Paper read before the late meeting of the Canadian Medical Association, held at Kingston,
Ont., and recommended by a resolution of that Society to be published in the press and a copy to
be forwarded to the Militia Medical Department.]
Gentlemen, — I fear that the subject of my paper will not appeal to
the sympathy of a large number of those present, unconnected with
the militia medical service; but I count upon your kind attention and
support nevertheless, knowing that neither is ever wanting to those
seeking honestly to efifect improvement in any branch of our profession.
The same subject has been lately discussed at a meeting of the Mari-
time Medical Association, held at Halifax, N.S., in July last, when
Dr. Farrell, whose brilliant paper you heard read last night, and whom
we from the Maritime Provinces are proud to find occupying such a
prominent position at this gathering, in the course of his presidential
address dwelt largely on "the incomplete organization of the medical
department of our militia."
" The Militia Department of Canada," he stated, " costs us a great
deal of money, and the people willingly grant what appears to them
154 THE CANADIAN MEDICAL RE\'IE\V.
to be a large sum of money, feeling that a military force for our pro-
tection and defence is a necessary part of our national existence. It
is the duty of every nation to be prepared for the terrible emergency
of war. To be prepared for action is the raison d' etre of the existence
of a militia. ' Ever ready ' in every department when the time of action
comes should be the aim of a well-organized force. It is for this object
that the country spends its money and our young men give their time
and energy to assist the work. To be prepared, each part of the system
should be a perfect organization in itself. The medical department I
will not speak of as being poorly organized — it is hardly organized at
all. The medical department is a most necessary part of the service
in the field, and if every other pait of the system gets proper attention;
this service sliould not be neglected. I will urge, again and again,
that the medical department of our militia should receive more atten-
tion and be put in proper shape."
The doctor then went on to say that the ordinary training of a gen-
eral practitioner is not sufficient for a military surgeon ; that the present
plan of medical organization is old-fashioned and not in touch with
modern military science, and he concluded by recommending a
reformation of the system and the establishment of chairs of military
surgery in the different medical schools throughout the Dominion.
In replying to Dr. Farrell's caustic criticism of the department, I
was much jileased to be able to point out to him and to the meeting
what had lately l)een done and what had been suggested for improving
the militia medical service. I could only deal with the suggestions
offered by myself, being ignorant of the labors of others — perhaps
more competent than I am — to inaugurate adequate reforms.
The following changes, at different times, had been submitted to the
Ministers of Militia and Defence :
(i) The reorganization of the ser\ice on a departmental — in lieu of
the present, the regimental — system.
(2) The formation of a reserve corps of medical officers on the same
basis as that of the British army medical service.
(3) The perfection of the ambulance system by the formation of
bearer companies to give " first aid " and transport to the sick and
wounded in war.
In discussing the question of reorganization, I informed the meeting
and the committee subsequently appointed to deal with the matter, that
I had had excei)tional facilities for becoming acquainted with the rela-
tive merits of the departmental and regimental systems, as I had had
personal experience of each, in the Queen's service and the Canadian
militia, both at home and al)road.
THE CANADIAN MEDICAL REVIEW. 155
I had served in India and at liome both as a regimental assistant
surgeon (in the 24th Regt.) and as a surgeon in the Army Medical
Department. Being in Canada in 1885, I had volunteered and joined
the Halifax Provisional Battalion on the breaking out of the North-
west troubles, and had served during the campaign in medical charge
of that corps. During that campaign I found the regimental medical
system as defective in the North-west as it has ever proved itself else-
where. So defective was it, as far as my own personal experience
went, that I was prompted to expose its deficiencies in a letter, over
my own signature, which appeared in a service paper, The Canadian
Militia Gazette, then being published in Montreal. The date of the
issue was the 2nd June, 1885.
To publish such a letter at the time was undoubtedly a breach of
military discipline which only a disinterested desire for improvement
in the service could or should condone.
Here is a copy of that letter :
"The Camp, Medicine Hat,
" 2ist May, 1885.
" To the Editor of the Canadian Militia Gazette.
" Dear Sir, — I should think it would be of interest at present to
medical ofificers serving with the troops at the front and throughout
the Dominion, if you would devote a space in your columns to a dis-
cussion of the relative merits of the regimental and departmental
medical systems. As an army surgeon of some ten years service, I
have had in my time experience of both. My experience as a militia
surgeon dates only from the beginning of the present campaign. I
have had, therefore, no opportunity of ascertaining the views of my
militia confreres on this subject, but I think the present time oppor-
tune and the column as appropriate for this discussion. At all events,
I have no doubt but that this campaign will have opened the eyes of
most of us to the necessity of reorganization. Should this take the
form of the departmental system now prevailing in the British service ?
It has been found in war time that the purely regimental system is a
failure. Has it not proved so on the present occasion ? Of course
our regimental hospitals have not been properly equipped as such, nor
have our field hospitals (such as I have seen of them at least) been put
on a proper footing. But would not a well-organized departmental
service have been more efiicient, more movable and cheaper than the
present one? With a Surgeon-( General at Ottawa, as head of the
department, one Deputy Surgeon-General for each Province with a
suitable staff of surgeons-major and surgeons under him (transferable
on duty, as required, from one point to another within the Province,
from one corps to another, and available for home and foreign service),
we would have a simple, cheap and readily movable staff, possessing
more authority, independence and esprit de corps than can ever be
obtained under the present system. I only throw out these ideas.
156 THE CANADIAN MEDICAL REVIEW.
hoping to obtain a ventilation of the subject, and having nothing but
agreeable reminiscences of both systems whilst in the Queen's service,
I consider myself as quite unprejudiced in the matter.
(Signed) "W. ToiiiN,
" Surj^eon, Halifax Provisional Batf."
The following was definitely the reorganization I proposed, viz., a
modified departmental system :
1. A Surgeon-General (at Ottawa).
2. Two Deputy Surgeons-(}eneral (one to act as statistical officer,
the other as purveyor of medical stores, etc., the second a position
which my friend, the Hon. Dr. Sullivan, filled so efficiently during the
Norih-west rebellion).
3. A Principal Medical Officer for each military district, who should
take medical charge of that district and have complete control of its
medical equipment.
4. .\ sufficient staff of surgeons-major and surgeons for each
district, so many per head of the active militia.
It was recommended that the present regimental medical officers
should be permitted to retain their positions and continue to wear tne
uniform of their respective corps, l)ut newly appointed officers should
be gazetted to the department and not be permanently attached to
any corps.
All medical officers should be under the orders of the F.M.O. for
the district. The P. .M.O. should correspond directly with the Surgeon-
General.
The Surgeon-General to be res[)onsil)le to the officer commanding
the militia in chief and to the Minister of Militia.
Such a militia medical department, subject to its own responsible
medical officers, would prove more efficient and more economical than
the present anticjuated and cumbersome regimental system, which has
been abandoned in the British service since 1872, as I had mentioned
in my letter to the press.
In this scheme for reorganization, I did not enter— nor do I propose
to do so now — into the details of the duties of each medical officer.
Those duties are clearly defined in the official regulations of the
Army Medical Department. This is merely the skeleton of a scheme,
the details of which may be worked out later on ; and, should the
exigencies of the service permit and no political conii)lications
hamper, I have hopes of seeing some such scheme eventually adopted
— whether at my suggestion or another's, whether it be my plan or
another's, is immaterial. A reorganization of the medical service is
urgently needed, and this, apart from personal or political consider-
ations, is what we, as medical men, should aim at.
THE CANADIAN MEDICAL REVIEW. 157
I have also proposed the formation of a reserve corps of medical
officers, somewhat on the basis of that of the British service. All
medical officers under sixty years of age, of good health and physique,
and whose previous service had been found satisfactory, might
voluntarily, and at any stage of their service, be placed on the reserve
list. They would be liable to be called upon to serve again either in
peace (optional) or in war time. In this way the services of such men
as Sullivan, Roddick, Bell, Douglas (late 24th), Cameron, Kerr (late
of Winnipeg), Elder, Shepheard and others need not be permanently
lost to the department. They might receive a step in honorary rank
on transfer to the reserve list and be compulsorily retired after sixty-
five years of age.
The formation of such a reserve list is possible even under the
existing (regimental) system ; and if, for any reason, it is thought
inadvisable to alter that system at present, that need be no bar to its
inauguration. The reserve bill would constitute a corps d^elite of
retired medical officers. It would (in times of peace) cost the country
nothing (an important consideration) and would afford a graceful recog-
nition on the part of the Government of previous good service. On
emergency, its members would form a part of the medical departments
ready to take their share of duty with troops at the base or in the
field, and preferably in military hospitals, where their previous
experience, military and civil, would be invaluable.
I had, at the same time, much pleasure in informing the meeting in
Halifax that, of late years, improvements had been made in the regi-
mental ambulance system there. Select classes have been instructed
in " first aid to the injured," under the officers of the St. John
Ambulance Society, in which society Surgeon-Major Lees Hall, of the
Army Medical Staff, and Dr. Carleton Jones, of Halifax, are zealous
workers. Both these gentlemen had volunteered their assistance as
instructors to the militia. In this work, however, I am sorry to say,
there has been a falling-off of late on the part of the men.
As regards the formation of chairs of military surgery, suggested
in Dr. Farrell's address, I was able to inform the author that the plan
had already been tried in Great Britain (after the Crimean war) and
had not proved a success. Such a chair had, for instance, been
established and was occupied by the late Surgeon Tuffnell, in the
Royal College of Surgeons in Ireland, but was soon abandoned.
So much, I was able to point out, in answer to Dr. Farrell, had been
suggested in the way of reorganization of the militia medical service,
and something, in fact, has already been done, for at stations where
permanent militia corps are established the medical service is worked
158 THE CANADIAN MEDICAL REVIEW.
rather on a departmental tlian a regimental basis. To attempt a
complete change may be considered premature, as it would certainly
be unpopular, at present. We know the heart-burnings that ensued
on a similar change being decreed in Her Majesty's service — but there
can be no doubt, nevertheless, that however socially agreeable to
individual officers, the regimental system on service has always failed,
and always will prove an utter failure. It stands condemned, and
must go if our branch of the service is ever to be made effective.
The idea of forming a proper reserve list appears to meet with more
general and official approva'. I have been asked to elaborate the
plan and furnish details, but at present I consider a modification of
our defective ambulance system and the formation of " bearer
companies " (at least in Halifax, which is exceptionally situated), of
more pressing importance. This was also the view taken by the
general meeting in Halifax, and by the committee appointed to deal
with the whole subject.
The following resolution was the outcome of the discussion :
" Resolved, That it is desirable that militia medical officers should
receive such instruction in military surgery, ambulance drill and the
routine of military medical administration generally as will enable
them to discharge satisfactorily their duties in the field, in camp and
in military hospitals. It is desirable that bearer companies should be
formed wherever possible in localities where several regiments are
brigaded together ; that the officers and men of these companies should
receive instruction in stretcher drill, in ambulance work and in giving
' first aid ' to the wounded ; that each bearer company should be pro
vided with a jiroper supply of medicines, surgical appliances and
ambulance furniture to enable officers and men to learn their duties
practically and to i)repare them to carry them out on emergency.'
This resolution was drawn up by the committee, was presented to
the full meeting and discussed, and was passed with a recommenda
tion that it be forwarded to the l)ei)artment. The part of the resolu-
tion dealing with the formation of bearer companies in connection with
our militia forces attracted particular attention, and elicited amongst
others the following remarks in support from Surgeon-Colonel O'Dwyer,
P.M.O. of Her Majesty's forces in Canada :
" It is considered desirable generally that bearer companies should
be formed in connection with modern armies, {a) because all Christian
nations now employ them in war ; (/>) because a bearer company, pro-
perly organized, saves much suffering to the wounded, and in many
instances, by timely and skilled assistance, prevents loss of life in the
field by bleeding, with which the medical officers available would be
THE CANADIAN MEDICAL REVIEW. 159
unable unassisted to deal. In these days of quick-firing rifles and
machine guns, the knowledge of a soldier that prompt and suitable
measures are at hand for treating him when wounded improves his
morale as a fighting unit. Nothing more depresses an army than to
be aware that assistance will not attend them when struck down."
The duties of a bearer company, I may mention, consist in giving
what is known as first aid to the wounded, and in removing them
promptly and properly from the field of battle. To perform these
duties efficiently they require a course of special instruction in such
elementary anatomy and surgery as will enable them to arrest haemor-
rhage, apply splints to fractured limbs, etc., and a course of stretcher
drill to teach them how to handle the wounded without aggravating
their injuries and remove carefiilly to a dressing station. No militia
or volunteer force is now considered effective in Great Britain without
having attached to it such a bearer company, which is quite distinct
from the regimental bearer organization.
Its formation need involve no loss of strength to the corps it is
formed from. The men may remain attached to their respective regi-
ments for purposes of discipline, drill, etc. In any case in time of
war or mobiHzation a similar number of men for similar duties (vide
Queen's Regulations) would be called for from each regiment in the
field, with this important difference, that the men then handed over to
the medical officers as bearers would be untrained and, perhaps,
unreliable ; whereas, should the bearer company system be adopted
the medical officers would have under their control a body of trained
men, competent and experienced to give every assistance to the in-
jured and remove them safely from the scene of action.
The men of the bearer companies should be selected preferably
from those who are already proficient in their ordinary duties, and,
when possible, from those who have already undergone a course of
instruction in first aid to the injured, as some of our militia men in
Halifax have done. They would continue to wear the uniform of
their regiment, and to serve with it ; but would be liable to be
detached when doing duty with the bearer company, and would
parade under the medical officers of that company.
The men of the bearer company, when formed, should receive
some distinctive badge, such as the Geneva Cross, as might be
determined by the Dominion Government.
In addition to the professional instruction in first aid to the wounded
which might always be given by their own regimental medical officers,
they would require a course ot stretcher drill under a competent
instructor.
i6o THE CANADIAN MEDICAL RE\TE\V.
In Halifax, should sanction be given to form such a bearer com
pany, or half-company (which will be sufificient for local purposes), we
propose applymg to the general officer commanding in Canada to
appoint such an instructor from the Army Medical Staff Corps. This
instructor will receive adequate recompense, the exjiense to be borne
out of local regimental funds. His services would only be required
long enough to teach the medical officers, non-commissioned officers
and men their stretcher drill. .-Yfterwards, ihe medical officers so
taught would be able to teach the stretcher drill themselves with the
aid of the regulation text-book, "The Manual for the Medical Staff
Corps," a copy of which should be in the possession of every medical
officer.
In Halifax we are exceptionally well placed, having a complete staff
of the Army Hospital C-orps to copy. In addition, we are fortunate
in having the Principal Medical Officer of the Imperial forces in
Canada, Surgeon-Colonel O'Dvvyer, with us, ever ready to give us the
benefit of his great experience in military medical matters. Surgeon-
Colonel O Dwyer has organized similar bearer companies in connec-
tion with the militia and volunteer forces in Creat Britain and
commanded a bearer column during the late Egyptian compaign. I
am delighted to see him present here to-day and hope he will favor
us with some practical remarks.
This scheme for the formation of a bearer half company in Halifax
has gone through the proper channel to Ottawa, and as it involves no
expense to the (Government and is urgently required, and in the words
of th:: local Deputy-Adjutant General, is considered 'a practical scheme
for a very necessary purpose," it is to be hoped it may meet with favor-
able consideration, and may prove the initiatory step in the direction
of a complete and effective reorganization, such as I have outlined,
of the whole militia medical service.
I will only add a few words to this purely technical paper, in order
to thank the Hon. Mr. Daly (our present (Governor of Nova Scotia
and late M.P. for the city of Halifax), and his successor in Parliament,
my friend, Mr. Thomas Kenny (who has always shown the greatest
interest in militia matters), for the kind assistance they have at various
times given me in bringing these views on service matters before the
heads of the Department; and also my thanks to the present and
various Ministers of Militia and Defence (Sir A. Caron, Hon. Mr.
Patterson and Hon. Mr. Dickey) for the invariable courtesy they have
displayed when I have had occasion personally to discuss these matters
with them.
TH& CANADIAN MEDICAL REVIEW.
ADDENDA.
Details of the medical personnel of a half-bearer company : Two
medical officers, one staff-sergeant, three sergeants, three corporals,
twenty-three privates (including officers' servants and a batman for the
senior non-commissioned officer) ; total, thirty-two.
In Halifax the medical officers are obtainable from the city corps,
which have two each, a surgeon and assistant-surgeon. The men have
been promised (ten from each of the city corps — H.G.A., 63rd and
66th Battalions) by the officers commanding, who warmly endorse
the project, as do also the medical officers of the three corps. We
await only the sanction of Government to organize, and as the plan
invoU'es no expense to Government, fail to see why there need be any
delay about getting it.
Cocaine in Urethral Surgery. — Any surgeon having much to do
with urethral surgery has noticed in some very modest and nervous
patients the extreme prostration from shock on passing any instrument
into the urethral canal, and much greater is this shock in these nervous
patients after passing a urethrotome, even though the cutting has been
very slight and no pain has been experienced. This I have noticed
many times. I have, used injections of cocaine in the urethra
hundreds of times, but I have never but once observed any symptoms
which I could absolutely lay to the cocaine. I have, however, never
but once used a ten per cent, solution. Two cubic centimetres of a
two per cent, solution is amply strong enough for the relief of pain in
deep urethral operations, while in cases of internal urethrotomy of the
distal end of the penile urethra not deeper than three inches I use a
four per cent, solution. In both cases the strength of the solution is
ample to completely anaesthetize the urethra. The solution should
not remain in the deep urethra longer than seven minutes at the
utmost. Usually five minutes is long enough, while in the distal
penile portion it will require seven to ten minutes to completely
anaesthetize this portion of the urethra. It should be seen that the
urethra is completely emptied of the cocaine solution by stripping it,
so that there is no further or prolonged absorption. By observing
these simple rules, and by using weak solutions, I have never since
encountered nor seen any alarming or poisoning symptoms from the
use of cocaine. — Dr. VV. H. Dukeman, N. V. Med. Jour.
l62
THE CANADIAN MEDICAL REVIEW
Clinical IRotce.
Multilocular Ovarian Cystic Tumor.
liY IJR. AI.HERT A. MACDONALD, TORONTO.
Mrs. C , referred to me in August by Dr. F. Cowan. She is a
well developed woman with yood family history, aged 27. Has had two
living children and one miscarriage, which took place in February,
1895. Since that time she has menstruated irregularly every two or
three weeks; the discharge has been normal in quantity, color and
consistency. I'or the past five months she has noticed a gradual
median abdominal enlargement to about the size of a five months'
pregnancy; general health unimpaired. On examination the tumor
was found to extend three inches higher than the umbilicus ; there was
Hack of tumor, showing X tube and its
fimbriated extremity.
dullness in the right Hank, resonance in the left. The tumor was
rounded and hard, lying in front of the uterus, and extending above it.
The uterus, apparently normal in size, could be moved separately from
the tumor, which had a firm feeling ; was not tender on pressure, and
had given rise to very little pain at any time.
Diagnosis, ovaian multilocular cystic tumor. Operation advised at
the earliest date possible. At Bellevue House, August loth, 1895, I
THE CANADIAN MEDICAL REVIEW.
163
opened the abdomen by a median incision and found my diagnosis veri-
fied. The tumor, a large multilocular cyst of right ovary (photographs
of which I show), occupied the whole of the pelvic cavity and extended
up into the abdomen, part of it lying under the right tobe of the liver.
I had to break up a number of the cysts before the tumor could be
lifted from the abdomen, though the incision was enlarged, both
upwards and downwards. There were no adhesions. The pedicle
was tied close to the tumor, cut off and dropped. The abdominal
wound was closed by silk worm sutures. The bowels were moved on
the third day. The recovery was uneventful.
i'ront ot tumor.
A point worthy of mention is that the patient was not ill in any way.
Thinking herself pregnant, even though she was menstruating, she did
not consult her physician until a few days before I saw her. He
then recognized the condition and sought consultation.
The course and results of ovarian tumors when left untreated cannot
now be studied, as the cases are recognized at an early date. In this
case the growth was rapid, for there was no tumor present when she
had the miscarriage in February. And if she had suspected anything
but pregnancy earlier advice would have been sought and an operation
would have relieved her when the tumor was small.
i64 THE CANADIAN MEDICAL REVIEW.
The Doctorate and the Military Law.
HV DR. SI'RAC.UE, STIRLINC, ONT.
jTranslated from Annalt'iide Medicine Scientififjut et Pratique, Paris, June, 1895.
The Board or Chambre has just discussed, not without warmth,
and adopted a text already voted to the Senate, a text that modifies
Article 24 of the law of the 15th July, 1889, which establishes the
military obligations of students, candidates for a doctorate. As is well
known, Article 24 requires that young men who are preparing for a
doctorate in either medicine, pharmacy, or law should have obtained
their degree of doctor at the age of twenty-six, under penalty of going,
at this age, to finish under the flag the three years of military service,
of which otherwise they would be subjected to only one year.
The house-surgeons of the hospitals, although not doctors, have,
alone, the right to pass their twenty-sixth year without obtaining their
doctorate, and the military law does not affect them until the end of
their inicrnat : but that is under this condition, that they should have
been called before a faculty, and in a city where there is a Faculty
of Medicine.
Now, since the 31st July, 1893, a rule, of which the application
commenced at the beginning of the present school year, requires young
men who wish to devote themselves to the study of medicine to be
holders of two bachelorships and, in addition, of a certificate testifying
to the regular attendance of a course of lectures of a Faculty of
ience for a year, this course being ended by an examination of
which the certificate shall render account. The druggists must serve
three years' apprenticeship in a laboratory added to three years of
school with twelve terms. Now, it is generally l)elieved that the twelve
terms recjuire four years. That makes seven years for the druggists,
besides the year of military service. Thus if the young druggist leaves
school at the age of nineteen he cannot, before twenty-seven years,
arrive at his nomination of druggist of the first class.
The medical students are, perha[)s, even more sure of being forced
by the military law. The medical studies, according to M. Bronardel,
demand seven years ; the year of service added makes eight years. If
the young aspiring doctor has not commenced at the age of eighteen
or has not had the chance of being named as house-surgeon, he can-
not escape the extra military service.
Such is the question. It was almost useless to repeat it, it having
been already determined. Despite that they had, at the Board, a
long discussion, sometimes picturesque ; the Commission, represented
THE CANADIAN MEDICAL REVIEW. 165
by M. Le H , was in favor of granting the extra year voted
by the Senate, granting the student until the age of twenty-seven to
obtain his doctorate without being forced to two extra years of military
service.
M. L , who was indeed in the debate, and who declared it
haughtily, supported this necessity of correcting an error in calculation
between a law of 1889 and a rule of 1893.
General Zurlinden, who is surely interested by the recruiting, being
Minister of War, declared that the Government was in favor of the
modification. He declared that the military organization had not
compromised itself at all, for now the young men should enter the
service at the age of twenty-seven years instead of twenty-six (I take
this as a sarcastic joke) if, as one might say in the military phrase, he
fails the (^some pun that loses its force in our language ?) doctorate.
The Minister of Public Instruction approved, once more, in the
name of the Government, of an additional year. " It is decided,
then ?" " Not at all : the Board wishes to make some changes."
M. Georges Berry asked if the extra year was also given to candi-
dates for licentiates in law. M. Reil replied that the Board refused
M. Mirman's reprieve, not for being merely medical doctor, but for
exercising his commission of deputy. He complained of inequality,
declaring that the preparation for a commercial career is quite as
intricate as that of a medical career. And M. Jourde followed M.
Reil on this ground of equal claims.
And it is not yet ended. The deputies of cities containing
schools of medicine asked that the internat for their internes named at
a gathering, give to them the same privileges as are granted to cities
containing a faculty.
Then noon came ; and then the whole south arises. M. Bouge
foretold the instant transfer of the Faculty of Aix to Marseilles so as
to change the school of M into a faculty. But M. M ,
President of the Commission of the Army, interfered, and the amend-
ment of M. Bouge was not voted.
" The law is adopted," said the Journal Officiel. The doctors of
the future have, then, an extra year, before running the risk of return-
ing a second time, and two long years to terminate an interrupted
" military career."
it)6 THE CANADIAN MEDICAL REVIEW.
Socictp 1Rcport^3.
Toronto Clinical Society.
The twenty-fifth regular meeting of the Toronto Clinical Society
was held in St. George's Hall, Elm street, October 9th, 1895.
Dr. J. E. CjR.\ha.m occupied the chair and read his inaugural address.
He said he felt it an especial honor to be chosen as president of a
society which had for its object the study of the clinical subject of
disease. The most useful information was that acquired at the bed-
side. All due credit must be given to the bacteriologist and the
pathological histologist for all the light they may throw on the subject
of disease as the result of their labors, but we must not underrate the
knowledge acquired from observation at the bedside and from a
careful examination of the gross appearance of the organs on the post
mortem table.
In a review of the history of medicine during the century that
was closing, several eras could be noted. The first might be termed
the clinical era, that in which Laennec, Bright and Addison flourished.
In our practice to-day we probably owe as much to these observer's as
to those of more recent date. Laennec's work on stethoscopy was a
finished work. The modern stethoscopist had added very little in this
department, while some valuable hints of Laennec's had been forgotten.
They had few instruments of precision, yet so accurate were their
observations and so careful their reasoning that the results achieved
have stood the criticism of hundreds of observers and stand as facts
to-day.
A second era was that of the morbid anatomist, represented by
Rokitansky and Virchow. From this period the microscope dated its
pre-eminence. In clinical medicine the thermometer was introduced.
In 187 1, the essayist said he had the privilege of attending Rokitansky's
lectures. He was not a popular lecturer and his classes were small.
His work, however, was still standard and had helped to form the
ground-work of our morbid anatomy. Reference was then made to
the great work of Virchow on Collular Pathology. The work of these
distinguished men was being carried on by their disciples, Conheim,
Von Recklinghausen and others.
The next era was that of bacteriology, commencing between the
years 1875 and 1880, when Pasteur made his discoveries in this depart-
ment. But it was not until 1882, when Koch discovered the tubercular
bacillus, that the profession first became interested in this branch of
, THE CANADIAN. MEDICAL REVIEW. ..i6.7
science. Since then it has undergone most rapid development. Fol-
lowing the isolation of micro-organisms, pathological and benign, the
attention of scientists had turned to the study of the toxines produced
by the bacteria. Many pathological processes originally ascribed
directly to the bacteria were now shown to be caused by those toxines.
During the past ten years the attention of investigators had been
turned to the study of the symptoms of the patient during life. Now
they were aided with many instruments of precision. A more elabor-
ate analysis of the secretions and the excretions of the body during
health and disease could now be made. Bouchard was prominent in
this line of study. The essayist referred to the work being done in
Johns Hopkins in this department. The attention paid to examina.
tion of the blood and the urine was commented upon ; the carefu]
analysis of these would assist very materially both in the etiology and
the treatment. It was to be remembered that diseased organs changed
after death. As an example the speaker referred to the disappearance
of an eczema after death. The great advancement of the future would
be made in the study of pathogeny rather than of morbid anatomy.
The essayist then spoke of the value of photography in the study of
disease. He advanced the opinion that if the phonograph could be
applied to the registering of heart sounds it would be of great service
in the study of cardiac diseases. There were many abnormal heart
sounds, apart from murmurs, which had not yet been definitely de-
scribed, but which indicated an abnormal condition of the organ.
Much careful study was required yet in the study of the animal
fluids. Much of the present study of them was a mere matter of
routine. The analysis of these must be pushed still further.
Dr. Graham then alluded to some recent advances in the line of
treatment of disease. Treatment by serum therapy had been success-
ful in diphtheria and tetanus. Animal extracts were now a recognized
form of treatment. The thyroid extract hid become an established
means of treatment of myxoedema. An embrologist had made the
remark to him the other day, how difficult it was for the physician to
attempt the cure of disease when so little was positively known of the
very foundations of life, of cell development and cell growth. His
reply was that there wjre human beings ill all about us who must be
attended to in the best manner known to us. Treatment could not be
deferred until the physiologist had explained the phenomenon of
existence.
A Case of Abdominal Aneurism. — Dr. A. A. Macdonald read a
paper containing the history of a case of abdominal aneurism. The
patient was a man aged 48, always strong and healthy. He was a
.68 THE CANADIAN MEDICAL REVIEW.
railroad man and his work had been that of a heavy nature. About
two years ago he noticed, after a heavy Hft, a pain in the abdomen. He
thought it was a strain caused by the Ufting. His physician was
unable to tell what was the matter. Some time after this he noticed a
lump on a level with and to the left of the umbilicus. He had some
pain in this lump but it was not severe. Shortly after this Dr. Mac-
donald was called to see him. He was then suffering from cough the
result of bronchial irritation ; he had diarrhoea and vomiting and was
losing flesh rapidly. The vomiting was a marked feature. At that
time the pain was noted a little below the region of the pylorus. So
marked was the condition that it was considered, possibly, cancer of
the pylorus. The tumor was not movable, it was hard and rounded.
The diagnosis was unsatisfactory. Patient was advised to enter the
hospital and have an exploratory incision made. The patient was
very anxious to know if a cure could be promised ; he was answered
in the negative. The operation was not urged. The patient decided
to wait. The diarrhcea Ijecame dysenteric in character, and was not
easily checked by the ordinary remedies. Urinary analysis, negative.
Ascites followed to such an extent that the lump could not be reached
by palpation, .\bout this time Dr. Baines was given charge of the
case.
Dr. Raines said he saw the case on the 22nd August. The patient
was suffering from dyspnoea, anasarca and marked ascites. Calomel
and magnesium sulphate were freely given, causing three or four
motions in the twenty-four hours. Nitro-glycerine and digitalis were
administered. A week after he entered the hospital he was tapped
and eighty-four ounces of fluid drawn from the peritoneal cavity. This
relieved him a good deal for the time being. There was at this time a
very slight trace of albumen in the urine. On September 5th he was
put on Guy's pills, one every four hours. On September 15th he
was tapped a second time and 134 ounces drawn off. This relieved
him again for a few days. September 25th he was obliged to take to
his bed, which he had not done up till this time in the hospital. His
neck was markedly swollen. The throat was examined and oedema
of the glottis was detected. In a few hours the man died.
Dr. B.MNK.s said that he iiad had the patient admitted to the hospi-
tal with the idea that cirrhosis of the liver was present, although many
of the clinical signs were wanting ; there was no jaundice nor any
marked tenderness over the liver. He had not known of the lump
previously ; he had not noticed it when examining the abdomen. The
walls were thick with layers of fat, and this with the oedematous con-
dition made it impossible to detect any tumor in the cavity. The
THE CANADIAN MEDICAL REVIEW. 169
pulse was small, rapid and dicrotic. The diagnosis rested between
cancer and cirrhosis.
Dr. H. B. Anderson reported on the pathological condition found.
There was great general anasarca ; there was effusion into the serous
cavities — the pleura, the pericardium and the peritoneum. There
was marked hypertrophy of the heart. The lungs were markedly
emphysematous ; the liver was congested ; the kidneys were also con-
gested and the capsule adherent to a certain extent. The surface of
the kidney was rough and there were some small cysts beneath the
capsule ; the intestines were normal. The aorta was markedly
atheromatous with calcification. An aneurism was found at the site of
the superior mesenteric artery ; it was about four inches in its long
diameter and three inches across, being oval in shape. Laminated
clots filled the superior mesenteric so as to completely occlude it.
The remote portion of the artery had dwindled into a fibrous cord;
the aneurism had not made pressure posteriorily ; it had pressed for-
ward and was firmly adherent to the head of the pancreas, which
organ it had shoved upward, causing pressure, which was exerted on the
structures in the portal fissure. The mesenteric artery did not seem to
be enlarged. A microscopic examination of the kidneys showed an
increase in the interstitial connective tissue and a hyaline condition of
the glomeruli. The collateral circulation could have been carried on
through the pancreatico-duodenalis superior from the hepatic
anastomosing with the pancreatico-duodenalis inferior from the
superior mesenteric, besides by the colica media of the superior
mesenteric anastomosing with the colica sinistra branch of the inferior
mesenteric.
Dr. Macfarlane asked if any bruit was heard when the case was
first examined.
Dr. Macdonald replied that there was none in front ; he had not
listened at the back as he had not suspected aneurism.
Dr. Grasett said it was not clear to him how collateral circulation
was kept up.
Dr. Macfarlane said that he failed to see how the collateral cir-
culation was carried on, as the aneurism seemed to be a healed one
and completely occluded the aorta.
Dr. Anderson pointed out that the lumen was not completely closed.
Dr. Meyers read an interesting account of a recent visit he had
made to Lourdes.
Metrorrhagia Cured by Ovariotomy. — Dr. Bingham reported the
history of a case of metrorrhagia cured by ovariotomy. The patient
was referred to him by Dr. M July 15th, 1894. The patient was
the mother of two children, the youngest of whom was ten. For nine
.,l.7.o THE CANADIAN MEDICAL REVIEW.
years she had been a sufferer from menorrhagia. She flooded for
about fifteen days out of each month, during which time she was bed-
fast. She lost enormous quantities of blood. She was very bad
during the past fiye years, having to keep in bed most of the time.
When she came to the city for treatment by him she was exceedingly
feeble, was much emaciated and complained of a very great deal of
pain in the back and down the thighs, showing that there was pressure
on the sacral plexus. Altogether she was in a very bad condition.
On examining the uterus nothing was found to account for the
.severe haemorrhages in the way of local tumors or myomatous masses,
except some small bean-like masses in the broad ligament. The
uterus itself was very large and flabby and was movable. She was put
in St. John's Hospital. He considered it a case for electrical treat-
ment, thinking that if electricity would do any good it should in a case
like this, being a case apparently of simple involution with great
prostration and anaemia. Electrical treatment was persisted in for
eight months. At the end of that time her condition, as far as the
loss of blood was concerned, was not improved. Her general health,
however, was improved. Thorough treatment by currettement and
tamponage and the other routine treatment having been previously
tried without any improvement, the woman in March, 1895, consented
to undergo radical treatment for the cure of the condition. The
operation was a simple one. The right ovary had connected with it a
cyst, the left was normal. The uterus was as large as one would
expect to find it in the third month of pregnancy. It was flabby, soft
and congested. The principal point in connection with the operation
was the difficulty of controlling the oozing. It was afterward learned
that the woman was a subject of haemophilia. For years after the
slightest scratch on the hand the bleeding was very difficult to check.
It took three-quarters of an hour to control the bleeding of the stump
and from the fundus itself where there had been some adhesions. A
drainage tube was inserted and the wound closed in the usual way.
The tube was pumped out every fifteen minutes for several hours. The
wound healed by first intention. The patient made an uneventful
recovery. She was now able to attend to her household duties. The
speaker said he would like to know why the electricity failed to help
the case.
Dr. A. A . Macdon..\ld said his opinion was that the benefit
from the use of the electricity was due to its astringent and escharotic
action on the uterine mucous membrane, but that it would have no
effect on curing the ovarian condition.
Dr. B.'MNES said that he had found electricity very beneficial in
these cases. The society then adjourned.
THE CANADIAN MEDICAL REVIEW. 171
Toronto Medical Society.
The regular meeting of the society was held on the 24th October in
the Council Buildings, President VV. H. Oldright in the chair.
Diphtheria in an Infant. — Dr. W. J. Wilson reported a case in
practice — diphtheria in an infant one day old, contracted from the
nurse. The history had been given him by Dr. Rowan, of Stouffville.
On September 24th the doctor was called to see a woman aged 22,
married, in confinement. Found that she had been delivered of a
child twenty-five minutes before ; the placenta was not yet expelled.
A neighbor woman had washed and dressed the child. After the
third stage was over the uterus contracted well. The neighbor washed
the mother's genitals with carbolized water. As he was retiring from
the case the neighbor reported that two of her children had sore
throats ; he was asked to see them. There was a large amount of deposit
in their throats. The mother had been washing the children's throats
out before attending the confinement, and had not washed her hands
after doing so. Eight hours after the delivery the infant's umbilical cord
was washed with a solution of boracic acid and dusted with a mixture
of iodoform and boracic acid powdered and covered with absorbent
cotton. The mother was sponged with a carbolic wash three times a day.
On the fourth day there was slight cedema around the umbilicus. The
next day this was increased and assumed a coppery red color. The
same day the stump separated. On the sixth day the umbilicus was
covered with a false membrane. This condition continued until the
tenth day, when the child died. On the fifth day the mother's labia
appeared oedematous; on the sixth this was increased and the discharge
became malodorous. A diphtheritic deposit appeared on the genitals
and inner portions of the labia. The breasts ceased to secrete ; the
temperature rose, and on the twelfth day vomiting set in. Death
ensued. There was a little deposit in the throat. From the ninth
day the oedema of the vulva was very great. The labia became tense
and crowded together. There was no tenderness over the uterus until
the thirteenth day ; on the fourteenth the uterus was tender and en-
larged. The treatment consisted in the use of carbolic lotions until
the sixth day. When the discharge became foul bichloride and per-
oxide of hydrogen were used, and a pad saturated with a solution of
permanganate of potash placed between the labia. The throat was
sprayed with Dobell's solution. The patient was given food and
stimulants freely. Nitro-muriatic acid and strychnia were administered.
Suppurative Cholecystitis. — Dr. H. B. Anderson read a paper on
Suppurative Cholecystitis with rupture of the gall bladder, complicating
172 THE CANADIAN MEDICAL REVIEW.
ty[)hoid fever. The patient, J. S., was admitted to the Toronto Gen-
eral Hospital September i6th. He was able to work at his trade in
Detroit till July 6th, when he was taken suddenly ill with chills and
fever ; vomiting and diarrhoea, with acute abdominal pains. Chill
•occurred daily. He was treated for malaria. He recovered and
returned to work again August ist, still feeling miserable. He was
taken worse in a few days, ("hills, fever, vomiting, diarrhoea and
headache with a good deal of abdominal pain on the right side were
the principal symptoms. He was again treated for malaria, taking
<]uinine till cinchonism was produced, with no result. He was ex-
amined before the Mississippi Valley Medical Association. Malaria
was diagnosed. Of several other men who were working with him and
similarly affected, two had died. The patient came to Toronto
September i6th. Was placed under the care of Dr. Davison at the
hospital. Dr. Davison being absent, the reader had charge of the
•case. The malarial parasite was first looked for, but none found. This
examination was repeated for several days with a negative result.
The blood showed six million red cells ; haemoglobin normal ; leuco-
■cytosis present, there being an increase of the polynuclear leucocytes.
Malaria was thus excluded and some acute inflammatory process pointed
to. The temperature was ranging from normal to 102. The pulse
was soft and of a low tension. The tongue was dry, red and tremu-
lous ; lungs and heart normal ; mind clear ; abdomen on the right side
full and prominent and tense ; left abdomen soft and lax. Palpation
.and j)ercu3sion produced intense pain on the right side all over the
region of the liver in front and behind and some distance below. It
was difficult to define the area of hepatic dullness on this account.
Th -re was no pain or tenderness in the right iliac fossa. There was
no enlargement of the spleen and no eruption seen on the body.
Urine negative. Erlich's reaction was not tried.
Diagnosis : Probably abscess of the liver. There was no history
of gall-stones or jaundice. There was swelling beneath the ribs below
the ninth intercostal cartilage. On the fifth day after admission the
intense pain and swelling disappeared and the patient felt compara-
tively better. This was soon followed by general abdominal tender-
ness. The temperature arose to 103, but fell to normal on the evening
of each day. The pulse became rapid and weak. Involuntary evacua-
tions of urine and feces took place. Patient grew unconscious and
died on the 26th, eleven days after entering.
Autopsy: General peritonitis, acute, with considerable brownish
yellow fluid in the cavity, bile-stained, which contained many polynuclear
cells containing yellow pigment. Bacteria in the form of curved rods
THE CANADIAN MEDICAL REVIEW. 175
and rounded ends present. The small intestines were bound together
by recent inflammatory adhesions. The solitary glands were swollen
and ulceration present in a few of Peyer's patches. The floors of ihe
ulcers were clean and smooth, and appeared three or four weeks old.
The liver weighed four pounds and showed passive congestion. The
cystic duct was obstructed by gall-stones. The mucous membrane of
the gall bladder showed ulcerated patches. The tissue between the
ulcers was reddened and congested. On the right side of the gall
bladder, one and one-half inches from the margin of the liver, one
ulcer had perforated through into the general peritoneal cavity.
Externally there were adhesions to the liver by a fibrinous deposit.
The gall bladder was greatly dilated. The spleen weighed six ounces.
Cultures from the peritonitic fluid showed a rod bacterium, short, with
rounded ends, somewhat constricted in the centre. In places they
formed threads. It corresponded to the bacillus typhosus or the
bacillis coli communis. An alkaline culture was made ; no ingol was
found, which proved it was the bacillus typhosus. The doctor referred
to the comparative rarity of this complication ; to the power of the
bacillus typhosus to set up inflammation, and the marked leucocytosis,
and to the ease with which malaria was excluded by microscopic
examination of the blood.
Dr. Peters asked if the swelling in the neighborhood of the ribs
was apparently due to congestion of the liver, or if it was localized to
the neighborhood of the gall bladder, and how many days before death
it was noticed.
Dr. McPhedr.^n asked if the attack in July was not due to gall-
stone impaction in the cystic duct leading to dilitation of the gall
bladder. He ^could not see how the bacillus would get up the duct.
He thought the infection was more probably h?ematogenous. He asked
if the spleen was a typhoid one, and if there were any cultures made
from it ; if the chills and fever were due to the biliary infection. He was
glad attention had been called to the condition of the blood. It was
quite remarkable that the red cells and haemoglobin were normal after
so long an illness.
Dr. Peters said that the question of a possible operation had
occurred to him ; would it be possible in such a case to operate on
such a gall bladder and drain ? Of course, the operation would be a
very severe one on a patient in so low a condition. If one could
diagnose positively the distended condition of the gall bladder he
would probably recommend operation, although there would be great
danger attending it. In the case presented there was no mode of
escape for the pus from the gall bladder, and any operation would be
174 THE CANADIAN MEDICAL RE\ lEW.
incomplete with an attempt to evacuate the duct. He com|)Hmented
the essayist on the cHnical and patholo3;ical report of the case.
Dr. Oi.DRiGHT called attention to the great difficulty of knowing
what to do in such cases. This had been his experience.
Dr. H. Walkkr thought an exploratory incision could have done
no harm, at any rate ; it might have led to a successful issue.
Dr. Anderson said that when the trouble first appeared there was no
localized tumor ; but about the fourth day the fullness opposite the
ninth intercostal cartilage appeared. The tenderness was all over
the liver, it was not localized. The swelling in the neighborhood of
the gall bladder was not noticed till later. He thought it was a case
for surgical treatment and reported it to the surgical side, but he
understood it was considered too late for interference. The spleen
was typhoid in character, but no cultures were made from it. There
were no marked symptoms of typhoid.
Atropia Poisoning. — Dr. R. J. Wh.son read the report of a case of
atroi)ia poisoning. Mrs. C- , aged 24. About noon drank a solu-
tion of atropia, containing i y^ grains. Reader saw her with Dr.
M an hour and a half after taking the solution. She had then
been vomiting at intervals for a few minutes and was drinking hot
water. The pupils were widely dilated, pulse 120, respiration 12.
Administered ^ grain of morphia hypodermically.
2.15 p.m. — Pulse 144, respirations 8, pupils widely dilated, patient
delirious. Gave ^ grain of morphia.
3.00 p.m — ^Pulse 120, respirations 6. No change in the size ot
the pupils.
4.30 p.m. — Pulse 104 and weak, respirations 4, Y^^ grain of morphia
given, and ^ grain of pilocarpine.
5.30 p.m. — During the last hour employed artificial respiration
with no success. The breathing was stertorous, expiration being pro-
longed, face livid. The pupils showed slight decrease in size, skin
cold, temperature in axilla 97.6. Injected 5 drachms of brandy and
y^ grain pilocarpine.
6.30 pm. — Pulse 120, respirations 5, skin warmer. Administered
2 drachms of brandy, also ],{ grain morphia and )'i grain pilocarpine.
7.30 p.m. — Pulse 120, stronger, respirations 6, m irked decrease in
the size of the pupils. Injected i >4 drachms of brandy.
8.00 p m. — ^Respirations 7, consciousness returned, more color in
face.
8.30 p.m. — Respirations 8, recognized faces, but could not see
small objects distinctly. Had diplopia. Bathed limbs and chest
with hot water, and applied hot water bottles to body.
THE CANADIAN MEDICAL REVIEW. 175
10.00 p.m. — Respirations 9, slight perspiration on chest.
11.00 p.m. — Pulse 120, respirations 12, perspiring freely. The fol-
lowing day patient could not see to read, but on the second day the
vision was quite normal. Recovery was uninterrupted.
Dr. Wilson reported a second case : A little girl, aged 5, had taken
a quantity of linimentum belladonna. The child was quite red when
he saw it an hour after. The temperature instead of being subnormal
was abnormally high, being 108, and after the death of the child it
had risen to no. Another feature was, the child had tetanic spasms
coming on about four hours after she had taken the belladonna.
Dr. Oldright pointed out that the maximum doses in the B. P.
were too large. In a prescription he had written he had put down
grain 1-25 of atropia. When he visited the patient next day she had
an eruption, the face was flushed and the throat was dry. She did
not repeat the dose. He found that the druggist had put in 25m. of
solution of atropia, making a 2m. dose, a much larger one than had
been ordered, being about 1-12 of a grain. The dose in the B. P.
was I to 4m.
The president stated that he had changed in a prescription con-
taining atropia r-ioth to i-2oth by writing the 2 heavily over the i in
the denominator ; but the druggist had misconstrued it to mean ^.
After taking a dose the patient had a very uncomfortable night. He
related two other cases where the patients had taken a quantity of
belladonna liniment instead of some other medicine meant for internal
use, by mistake. But by the use of morphia and the stomach lube
recoveries took place in both cases.
Dr. James McCallum related the case of an old man who was
undergoing treatment for his eyes, atropia gr. 4 to the ounce being
used for eye-drops. He was brought to the hospital in a state of
delirium, and it was impossible to tell whether he was suffering from,
alcoholism, atropine poisoning, or pneumonia. But the following
day discovery of the physical sign of pneumonia on 3ne side of the
chest revealed what the true condition was.
Dr. Webster reported a case in which an eruption appeared on a
young girl who was wearing a belladonna plaster. He had had another
case in which ^ grain tablets of belladonna had produced toxic
effects. The same dose repeated in pill form had no such effect.
He referred to another patient in whom i-ioth of a minim fid.
ext. produced a very severe headache and marked dryness of the
throat.
The society then adjourned.
176 THE CANADIAN MEDICAL REVIEW.
lEMtorials.
Graveyard Insurance.
Many attempts have been made, in every country where life insur-
ance offices are to be found, to obtain money fraudulently by securing
policies upon persons who were known to be diseased. These attempts
have, no doubt, succeeded on many occasions, but the prospects for
schemes proving successful in the future are rapidly growing less.
In order to work such infamous plans of fraud several parties must
be in each other's confidence. The risk must come through some
agent of the company ; the insured, or the person who is to be made
beneficiary under the policy, must be in the plot ; and the doctor,
who is to pass upon the risk, has his share in the transaction.
Now, it is well to remember that the companies have several means
of obtaining information 'regarding risks, which those who have evil
intentions should bear in mind. Among the companies there is an
exchange of inforniali jn as to risks that have been rejected, and of
medical men who are not deserving of trust either because of care-
lessness or dishonesty. There are also private bureaus, which make
it their business to find out, by careful enquiry, information about
agents, doctors or applicants.
Another thing that should be borne in mind is that persons of bad
health are almost invariably known to a certain number of people as
not fit subjects for life insurance. When a policy is sought, and
obtained, upon such persons, it soon becomes noised abroad; and
the agents of rival companies and the bureaus of information learn
the main facts. In this way it soon reaches the head office of the
company upon which the wrong has been practised. Immediate steps
are then taken to ascertain the true condition of affairs.
Still further, it must be borne in mind that the country is full of
those who carry policies in the several companies and societies. If
any one of these policyholders comes to hear of the fact that the
company he is interested in is being victimized, he is very likely to give
away his information, and in this way defeat the attempted fraud.
It must be said for the medical profession that very few indeed of
its members would be party to any attempt at fraud in this way.
But even to these very few scoundrels we would utter a word of warn-
ing. The fraud is almost sure to be found out, and may lead to very
grave results. Even if it be not definitely discovei*ed, it is likely to
be strongly suspected, and the doctor may thus lose a valuable con-
nection, and the patronage of the numerous companies.
THE CANADIAN MEDICAL REVIEW. 177
Vaccination Against Diphtheria.
At the opening meeting of the German Medical Congress at Lubeck,
Dr. Behring read a paper on the antitoxine treatment of diphtheria,
which is worthy of note. He stated that the mortality from diphtheria
had considerably decreased in all hospitals in which it had been
introduced. He denied that this was due, as was asserted, to the
mild character of the cases. He estimated that in the last twelve
months in Germany alone at least 1,000 had been saved from certain
death by the serum. Dr. Behring repeated the statement made by
him in Vienna that it would be possible by the aid of the serum to
reduce the mortality to 5 per cent. Further, he declared without
hesitation that the 400,000 doses prepared by the institution under
the supervision of himself and of Dr. Erlich had not contained any
injurious matter. He thought it was time to begin general vaccination
of children with the serum as a preventive of diphtheria. It had been
found possible to manufacture serum of such strength that the injec-
tion of only half a cubic centimetre ought to suffice to give complete
immunity to children who are not already attacked.
The Doctorate .\nd the Military Law. — Dr. Sprague, of
Stirling, has kindly furnished us with a translation from a French
journal, which appears on another page. This is most interesting in
view of the agitation which now exists in Ontario to raise the standard
of medical education and prolong the course of study.
To GET the feeling of the medical men on lodge and contract
practice in Toronto, the Western Territorial Division of the city are
circulating the following : I the undersigned medical practitioner
agree not to do any lodge or contract practice as soon as ninety-five
per cent, of the medical men of the city sign this agreement, and when
present contract expires.
Death of Mathieson, "The Eye Doctor." — On the 17th ult.,
there died in this city a somewhat remarkable character, who, for many
years, and in spite of frequent convictions of violation of the Medical
Act, carried on a business as an " eye doctor." His method was to
charge so much a week for medicines. He had a considerable hold
on the imaginations of the country people, who frequently came great
distances to be " doctored" by him. He had formerly been a private
soldier in a Highland regiment.
178 THE CANADIAN MEDICAL REVIEW.
Retirinc Ali.owances to Drs. J. Ferguson, W. W. Ogden and
M. H. AiKiNS.— After long delay and much discussion the Senate of
the University of Toronto passed a statute through all its stages
placing these gentlemen in the same position as though they had
resigned. The medical faculty, though by no means unanimously,
decided to send a committee to wait upon the Government to oppose
the confirmation of the state. Drs. I. H. Cameron, A. McPhedran,
and Prof. Pike composed the deputation fro-n the faculty. At a later
date Drs. W. W. Ogden and J. Ferguson were heard in behalf of their
contentions that the statute should be confirmed and the payments
made. The statute was confirmed by the (Government, November 5th.
Ontario Medical Librarv Association. — A meeting of the
Board of the Ontario Medical Library Association was held on Friday
evening. The following officers were elected : Dr. J. E. Graham,
president; Dr. L. McFarlane, ist vice-president; Dr. L. L. Palmer,
2nd vice-president ; Dr. W. J. Greig, treasurer; Dr. N. A. Powell,
curator ; Dr. J. H. Hamilton, secretary. The report of the Treasurer
was the most favorable one we have had for years. It showed that
the receipts had been able to keep pace with the expenditures. This
is due to the fact that a donation from the Ontario Medical Associa-
tion had been received, and that by-law xxxii., providing for the collec-
tion of the annual fee of $2 from each member, has been put into
operation for the first time. The hope was expressed that members
would respond promptly and by so doing help the Board to make the
library still more useful to its members. The report of the Curator
showed a substantial increase in the number of valuable books,, jour-
nals, etc., and many promises of donations were mentioned. The
Curator also reported that arrangements had been completed so that
members of the Ontario ^Medical Association could procure the loan of
books from the Surgeon-Cieneral's Library in Washington at cost of
express. This is a very valuable privilege for those engaged in
research.
Western Territorial Division Association of Toronto. — A
meeting of this Association was held at 4 p.m. on Thursday, October loth,
1895, at Broadway Hall. In the absence of the President Dr. Albert
A. Macdonald, the Vice-President, was called to the chair. After the
reading and confirming of the minutes of the previous meeting,
business arising out of the minutes was taken up. Prescribing by drug-
gists, repeating prescriptions, etc., was now discussed at length. The
THE CANADIAN MEDICAL REVIEW. 179
opinion was expressed that the work already done, and the meeting of
representatives of the Druggists' Association and members of this
Association has been productive of some good and a better feehng
and understanding, the druggists seeming wilHng to conform to our
views and to meet our requirements. The discussion of " club prac-
tice " came in for a large share of attention. It was admitted by
almost all of the members present that it was an evil which should be
got rid of, and at the same rime harsh measures were not urged. One
of the members held an opposite view ; he said that the members of
his clubs were most considerate and that he had received from one of
his clubs as much as $3.00 a visit. It was resolved that the members
of last year's committee, Dr. Spence, chairman, should be continued
and that they should find out the feeling of the medical men of
Toronto on the question of " club practice " by sending out circulars,
etc., and that the committee should report at the next meeting. The
question of "bad pay patients" was discussed, and it was agreed to
accept Dr. Mennie's offer to undertake the management of a " black
list," and to give him all possible support. The meeting was then
declared adjourned.
Why They See Snakes. — Dr. A. E. Davis, in the Post Graduate
for October, reports the results of a large number of examinations of
fundi oculi in patients suffering from delirium tremens. In all the
blood vessels were dilated and tortuous. He points out that the hallu-
cinations in ninety five percent, of these cases are those of sight, and
he believes that the "snakes" seen are most likely these vessels, which lie
in the anterior layers of the retina, being perceived by the rods and
cones which lie in the posterior layer.
Dr. Gowers' Address to Medical Phonographers. — The British
Medical JournaHox October 5th contains the inaugural address de-
livered by Dr. W. Gowers before the Society of Medical Phonograph-
ers on " The art of writing in relation to medical and scientific work."
Dr. Gowers characterizes the present mode of longhand as littte less
clumsy than when the Phrjenecians and Egyptians first gave alphabeti-
cal writing to mankind. He sets forth the unmixed advantages of
shorthand in the recording of clinical and other scientific data. It
enables the student to make a perfect epitome of his lectures, more
useful than any text-book, and yet give more attention to the subject
than if he took no notes. Experiment shows that two hours a day
with a lesson each day, in a fortnight a person can write at the same
speed as longhand and at the end of a month secure its practical use.
i8o THE CANADIAN MEDICAL REVIEW.
New Treatment for Severe Vomiting. — Dr. C. L. Greene, of
St. Paul, in Northwestern Lancet for October, claims that he has ob-
tained good results in uncontrollable vomiting by intubation of the
larynx. His theory is that unless the glottis is closed so as to fix the
diaphragm vomiting is not possible in the adult. To prevent the
necessary fixation of the diaphragm, a tube is placed in the larynx. This
permits the free ingress and egress of air, and obviates the spasmodic
closure of the glottis. When abdominal muscles contract the stomach
is pressed against the diaphragm. This yields, and the contents of the
stomach are not ejected.
Puerperal Convulsions. — Dr. Thad. A. Reamy, in Cin. Lancet
Clinic, 12th October, highly recommends the use of Norwood's tinc-
ture of veratrum viride in this disease. He gives twenty or twenty five
minims hypodermically. In the course of an hour it may be re-
peated if necessary. Soon after the depression the pulse falls in
pregnancy and becomes soft, and profuse perspiration sets in. If the
pulse again becomes frequent and hard the veratrum should be again
given. If the drug is followed by symptoms of dangerous depression,
these are speedily removed by the hypodermic injection of morphia.
It is noteworthy that this drug counteracts the depression of veratrum
and at the same time is valuable in the treatment of the convulsions.
It is in this way that the mixed treatment by veratrum and morphia is
so valuable in many severe cases of puerperal convulsions.
Address on Medical Education. — Professor Roswell Prark, in
his address on medical education at the fifth annual meeting of the
Harvard Medical Alumni Association, said, from a retrospective view,
what had hindered the progress of medical education in time past,
and that which being removed had permitted the rapid strides of the
last few decades, was the malign influence of the Church. The
Church and its authority had been the greatest enemy of medical pro-
gress in all past time. The subjects against which its authority had
been most obstinately wielded were those of anatomy and surgery.
Learning in the Middle Ages was confined to the monasteries, and
the monks were taught that to shed blood was without their pale, and
it was considered inpious to mutilate a form which was made in the
divine image. During the fifteenth and sixteenth centuries, although
public lectures on anatomy were held, the professor did not do the
dissecting ; he hired some barber to do it, and himself simply expound-
ed what the barber exposed. A recent step in the way of a medical
THE CANADIAN MEDICAL REVIEW. i8i
extension course they were adopting in Buffalo was the appli-
cation of the Chautauqua idea. A series of studies for three years was
to be laid down and a certificate would be granted on passing an
examination on the work. This was simply an incentive to home
study.
Medical Education. — Dr. Jonathan Hutchinson, in delivering
the opening address at University College, Liverpool {British Medical
Journal), speaking on the subject of medical education and referring
to specialism, says he considers it far better to have a general acquain-
tance with all that is around us, though it be not very deep, than slices
of profound knowledge, placed sandw'ch-ways between layers of utter
ignorance. His opinion on the examination evil is that the student
should be brought to feel that his examinations so far from being a
source of harass and won;y, are really his best friends, guiding his work
and at the same time guaging his attainments. He recommends that
a carefuUv prepared list of suitable questions be accessible to the can"
didates. He advises against viva voce examinations. To check
incompetent and idle men from entering the profession, the key is in
the hands of the examiner.
Military Medical Notes.
The French medical officers can hardly complain of want of official
recognition. In the last Gazette no less than thirty-four were created
as commanders, officers or chevaliers of the Legion of Honor.
A CORRESPONDENT of the Army and Xavy Gazette (London) com-
plains that medical officers whose names are put up for ballot at the
service clubs are almost invariably blackballed. The editor questions
the statement.
Suroeon-General Sir Thomas Longmore, C.B., of Southampton^
died suddenly at Swanga last month. He was born in 1816, and was
the son of a surgeon in the Navy. He was educated at Merchant
Taylor's School and at Guy's Hospital, and entered the Medical
Department of the Army in 1843. He served throughout the Crimea
campaign and in Bengal during the Mutiny. He was professor of
military surgery at Netley from i860 to 1891, and he had been hon-
orary surgeon to the Queen since 1868. He was the author of a
number of works, among them being " A Treatise on the Transport of
i82 THE CANADIAN MEDICAL REVIEW.
Sick and Wounded Troops," "Gunshot Injuries: their History,
Features, and Treatment," " Sanitary Contrasts of the Crimean War,"
and a " Life of R. Wiseman, Surgeon to Charles II." His "Optical
Manual" is the standard work in connection with the eyesight of
soldiers.
Thk death of Baron Larrey, third Napoleon's surgeon, recalls an
adventure of his father, the first Napoleon's medical adviser at Water-
loo. . The elder Larrey bore so striking a resemblance both in
physicjue and in dress to the Little Corporal that when he was taken
prisoner by the Prussians they thought they had captured the
Emperor, and ordered him to be shot. But the doctor who was
ordered to bandage his eyes recognized him as his old instructor in
medicine, and at his request Larrey was sent to Blucher, who gave him
some money and dismissed him.
IBooh H^oticci?.
A/i Illustrated Monograph on Oxyhccmoglobin and Allied Products.
Pul)lished under the direction of F. E. Stewart, M.D., Ph.C,
Director of Scientific Department, F. Stearns & Co., formerly
Demonstrator and Lecturer on Materia Medica and Pharmacy,
Jefferson Medical College, etc. Detroit : F. Stearns & Co. 1895.
This illustrated monograph of 56 pages emanates from the scientific
department of F. Stearns & Co. of Detroit, and is divided into three
parts. Part I., by Dr. Stewart, deals with Oxyhaemoglobin, albuminate
of iron, and peptonate of iron. Part II., written by Dr. A. B.
Macalluni, Associate Professor of Physiology, University of Toronto,
on the absorption of iron in the animal body, contains an account of his
investigations as to the alisorption of both organic and inorganic iron
compounds ; and Part III., by Charles H. \\'illiams, Ph.B., Ph.C, of
the School of Pharmacy, University of Michigan, is on the Haemoglo-
bins and related products of the market. The publishers are to be
congratulateO on issuing a work like this from their scientific depart-
ment— a departure in the right direction. They maintain that the
manufacturing pharmacist is comparatively little to blame for the
present situation in regard to proprietary medicines, in that he has
simply supplied what is called for, leaving it to the profession to create
a demand for something better. This the latter can now do by
co-operating in the work of their scientific department, and as an
evidence of liberal spirit they offer remuneration for such work as may
be done under their control or in the laboratories of the universities.
This brochure is entitled to a careful readins.
THE CANADIAN MEDICAL REVIEW. 183
Green's Pathology and Morbid Anatomy. Pathology and Morbid
Anatomy. By T. Henry Green, M.D., Lecturer on Pathology
and Morbid Anatomy at Charing-Cross Hospital Medical School,
London. Seventh American from the eighth and revised
English edition. Octavo volume of 595 pp., with 224 engravings,
and a colored plate. Cloth, $2.75. Philadelphia: Lea Brothers
& Co., publishers. 1895.
Green's Pathology and Morbid Anatomy has long been the leading
text and reference book in all English-speaking countries, a fact; indi-
cated by the number of editions demanded. A knowledge of the sub-
jects covered by its title is essential to graduation and not less so to
the practitioner, who must understand the nature of a disease as a pre-
requisite to rational curative measures. Thanks to the tireless
industry of laboratory workers and clinicians these sciences are in a
state of constant development, and in order to represent their existing
position, this volume has been thoroughly revised and new chapters
have been added. The previously rich series of illustrations has been
increased with sixty new engravings and a colored plate.
The general character of the work is maintained throughout notwith-
standing the numerous additions by various colUiborators, as all have
imitated the desirable conciseness and lucidity of the author. The
first chapter deals with arrested nutrition, after which eight chapters
are devoted to impaired and increased nutrition. Six chapters are
given up to tumors. Then diseases of the blood and circulation are
considered, then fever, inflammation, the vegetable parasites, the
infective granulomata, septicaemia and pyaemia, malaria, and diseases of
the special tissues and organs, and the last chapter, on the
pathology of the central nervous system by Dr. Mott, is a notable
addition admirably illustrated.
Saunders American Year- Book of Medicine and Surgery. Edited by
George M. Gould, A.M., M.B. ; assisted by eminent American
physicians and teachers. To be published by W. B. Saunders,
925 Walnut Street, Philadelphia.
Notwithstanding the rapid multiplication of medical and surgical
works, still these publications fail to meet fully the requirements of
the general physician, inasmuch as he feels the need of something
more than mere text-books of well-known principles of medical science.
This deficiency would best be met by current journalistic literature,
but most practitioners have scant access to this almost unlimited
source of information, and the busy practiser has but little time to
search out in periodicals the many interesting cases, whose study
i84 TFiE CANADIAN MEDICAL REVIEW.
would doubtless be of inestimable value in his practice. Therefore, a
work which places before the physician in convenient form an epitomi-
zation of this literature by persons competent to pronounce upon the
value of a discovery or of a method of treatment cannot but command
his highest appreciation.
It is the special purpose of the editor, whose experience peculiarly
qualifies him for the preparation of this work, not only to review the
contributions to American journals, but also the methods and discov-
eries reported in the leading medical journals of Europe, thus enlarging
the survey and making the work characteristically international.
This work will be replete with original and selected illustrations,
affording efficient aids to a right comprehension of the text, and adding
to the attractiveness of the volume. This work will be ready for
delivery January ist.
A Treatise on the Nervous Diseases of Children for Physicians and
Students. By B. Sachs, M.D., Prof of Mental Diseases in the
New York Polyclinic, Consulting Neurologist to the Mt. Sinai
Hospital, etc. New York: AVm. Wood tS: Co. 1895.
Clinical Lectures on Diseases of the Nervous System. Delivered at the
National Hospital for the Paralyzed and Epileptic, London. By
W. R. GowKRS, M.D., F.R.S., Physician to the Hospital, Con-
sulting Physician to University College Hospital, formerly Pro-
fessor of Clinical Medicine in University College. Price, $2.00.
Philadelphia: P. Blakiston, Son & Co., 1012 Walnut Street.
i<S95.
The author delivered these lectures at the National Hospital for
the Paralyzed and Epileptic. They were reprinted from various Eng-
lish medical journals, with the exception of two lectures, which are
reproduced by permission of the J. B. Lippincott Co.
This book is handy in size, and e.xcellent in print. The well-known
name of the author is a sufficient guarantee that the purchaser will
receive more than his money's worth.
The table of contents shows how the writer has dealt with subjects
attractive to the practitioner. Among the subjects lectured upon we
notice a chapter on "Mistaken Diagnosis," one on "The Foot Clonus
and its Meaning," two upon "The Infantile Causes of Epilepsy,"
two upon " Locomotor Ataxy," one upon " SyringoMyelia," and two
upon " Optic Neuritis."
There are other chapters covering rare forms of nervous disease.
Chapters 3 and 4 deal with argyria and syphilitic hemiplegia.
THE CANADIAN MEDICAL REVIEW. 185
One feature of this work is that a chapter is complete in itself, and
so comprehensive that a busy practitioner can take up the work and
tjuickly come at just what he is looking for. We confidently recom-
mend this book to our readers, and believe that it will be a help of
great value to the student and practitioner.
IPcreonale.
Dr. J. W. Early has removed to Owen Sound.
Dr. Hotson, of Innerkip, hrs removed to St. Mary's.
Dr. C. Shuttleworth, late of the General Hospital, has com-
menced practice on Broadview Avenue.
Dr. W. T. Wilson, of Dundas, has received an appointment as
assistant at the Insane Asylum at Brockville.
Dr. W. T. AiKiNS has been appointed to the Senate of Toronto
University as representative of Toronto School of Medicine, Dr. J. H.
Richardson will also be a member of that body as the representative
of University College Council.
Quick Passage of a Murphy Button. — In the Neiv Albany
Medical Herald, Dr. John M. Foster, of Richmond, Ky., reports the
passage of a " Murphy button " in less than three days after a resec-
tion of the bowel, with recovery. It came away with the first move-
ment of the bowels — sixty-eight hours after the operation. This is by
far the most rapid union of intestine yet reported, and it is in strange
contrast to the Nashville (Tenn.) man who was operated upon by Dr.
Cordier and myself ; this patient retained his button until the 15th
day, but recovery was perfect.
The Archives of Pediatrics will commence its 13th year with the
January number, under the business management of R. B. Treat, pub-
lisher, of New York, long identified with medical publishing interests.
The Archives has been for twelve years the only journal in the English
language devoted exclusively to " Diseases of Children," and has
always maintaiifed a high standard of excellence. The new manage-
ment propose several important changes in its make-up, increasing the
text fifteen per cent, and enlarging its scope in every way. The edi-
torial management will be in the hands of Floyd M. Crandall, M.D.,
Adjunct Professor of Pediatrics, New York Polyclinic, and Chairman
of Section on Pediatrics, New York Academy of Medicine.
i86 THE CANADIAN MEDICAL REVIEW.
A DEPOT for the sale of Dr. Jaeger's sanitary woollen underwear and
dress material has been opened in this city. These goods are well
known to the medical profession in Great Britain, on the continent
and in the United States, and have been most highly recommended
for their purity and essential goodness. A price list and full particu-
lars will be mailed to any member of the profession on application to
Wreyford & Co., 63 King Street west.
We would call the attention of the profession to a paper (published
in another column) by Dr. Thos. O. Summers, entitled " Pro-
tonuclein : Leucocytes and Nuclein." This paper was read before the
Section on Practice at the meeting of the American Medical Asso-
ciation recently held at Baltimore. The paper was illustrated upon
a screen, showing microphotographs of protonuclein and its action
upon the leucocytes of the blood. It is claimed that the introduction
of this agent will mark an era in therapeutics, and it is sufficiently
endorsed to warrant a fair trial.
The Morals of a Surgeon. — What a man does is the proof to
the world of what a man is. Many good people fear that the advance
of science will bring about the retrogression of morals and religion.
AVe do not agree with them. But if they cannot accept our judgment,
let them weigh well a fact like this : Mr. Jonathan Hutchinson, F.R.S.,
and e.\-president of the Royal College of Surgeons, addressed his pro-
fessional brethren assembled in annual congress the other day, and he
thus spoke : " I bore with such equanimity as I could the discovery
that I could not compete with my frijnd in the ratio of successes
obtained" (in operations for ovariotomy), "and, acting on the rule of
conduct that I would never keep a patient in my own hands if I
believed that someone else could do what was needed with greater
prospect of success, I gave up doing ovariotomies, both in public and
private, and used to transfer my patients from the London to the
Samaritan Hospital." Here is a rule of conduct which has never
been excelled in moral worth in any department of professional life or
p-rivate behavior. A most far-reaching and truly noble rule is this of
Mr. Jonathan Hutchinson's; and the fact that he announced it toward
the close of his career in the hearing of hundreds of his professional
brethren, who are almost as familiar as he is himself with the conduct
of his professional life, is i)roof that he sfjoke mere truth. If these
are the morals of men of science, may we not say of men of all pro-
fessions and callings, O si sic onines! — The Hospital.
THE CANADIAN MEDICAL REVIEW. 187
Illegal Practitioners.
Thomas Wasson's Report.
List of persons prosecuted and cases investigated by Detective
Wasson and his assistants, Constables Brown, Briggs, McRener and
Boyd for violation of the Ontario Medical Act in the various parts of
the Province since ist of January, with results : R. S. Gilmore, Wiar-
ton, fined $25 ; James Beaton, Kincardine, fined $25 ; Dr. G. J. Fell,
Ridgeway, fined $35 ; Kickapoo Indians, Stevensville, dismissed ; J.
McKelvey, St. Catharines, no case ; Henry Musson, Allenburgh, no
case : J. S. Powly, Toronto, fined $30 ; Mrs. Gilbert, Huntsville, fined
$27 ; J. W. Black, Toronto, fined $25 ; M. A. Graham, Toronto, fined
$25, skipped out ; A. McLeod, Owen Sound, no case ; A. P. Stirritt,
Toronto, fined $35 ; Ruth Beasley, Toronto, fined $25 ; Dr. Wash-
ington, Crysler, fined $50, has appealed; F. N. Cadeaux, Toronto,
dismissed ; W. D. McNabb, Tara, fined $25 ; Mrs. Bauvine, Berwick,
no case ; Mary A. Labrick, Toronto, left town : T. A. Pine, North-
brook, fined $25 ; F. H. McCarthy, Ottawa, fined $40 ; Dr. A. Oumet,
Ottawa, fined $25 ; Mrs. R. Thompson, Ottawa, fined $25 ; Mrs. A.
McKelvie, Ottawa, fined $25 ; Mrs. R. Lange, Ottawa, fined $25 ; S.
Townsend, Ottawa, withdrawn ; Professor Gustin, Orangeville, skipped
the town, warrant issued for his arrest ; J. W. Wesley, Petrolia, com-
mitted to jail ; J. McCarthy, Paris, committed to jail, subsequently
he paid his fine and was released ; laid another charge against Dr.
N. Washington, to appear at Chesterville on the 22nd inst. ; J. Bealing,
North Bend, withdrawn ; T. A. Pine, Flinton, fined $25 ; Andrew-
Robinson, Maberly, fined $25 ; A. Finlay, Mountain Grove, fined $25;
Mrs. John Kane, Ottawa, no case ; Mrs. Enoch Thompson, Ottawa,
no case; Mrs. Ann Kelly, Ottawa, no case; Mrs. M. Ackland, Ottawa,
no case ; Mrs. Sherron, Clarkstown, no case ; Mrs. Burton, Bytown,
no case ; Professor Glen, Wasego, fined $25 ; Dr. Jebb (oculist),
Orangeville, was billed for four days, stayed only one day and left as I
arrived there ; laid an information in Orangeville against J. W. Black,
of Toronto, case to come up on the i6th.
I have arranged with J. Hughes, High Constable of Dufferin
County, to assist me in that district. I am getting up evidence in two
cases against qualified practitioners, one east and another north, for
investigation by the Discipline Committee.
I have sent Brown to Palmerston and all through places in that
section where I hope to be successful. Next month I intend to go to
Muskoka and Algoma districts prosecuting.
Thomas Wasson,
Detective, C P. and S. O.
i88 THE CANADIAN MEDICAL REVIEW.
Protonuclein : Leucocytes and Nuclein.*
PA' THOS. O. SUMMERS, M.A., M.l)., K.K.S.C, LONDON, ETC.
I BELiEVic that St. Luke was the only physician upon the Apostohc
Board, and that he is the generally accredited author of " The Acts
of the Apostles," in which, describing the visit of St. Paul to Athens,
he declares parenthetically this very remarkable historic note :
" For all the .Athenians and the strangers that were there, spend
their time in nothing else but either to tell or to hear some new thing."'
And this neophilism which the great Apostle of the Gentiles has
given as an historic character to the " City of the Voilet Crown," has
descended unto us of later days, and it may be said with truth, that
among all the workers in the great field of science, medical men are
most eager for discovery and most earnest in the search for the ever
unfolding mysteries of truth. And notwithstanding the fact that this
spirit of investigation has often been held up to us by those who
profit by our labors, and yet are ever ready to sneer at our methods,
as the "opprobrium medicorum,"' it will be a sad day in the history
of medicine when we care not to " hear or to tell some new thing."
It is to a new departure in therapy, developed by recent investi-
gation, that I direct your attention in this' paper. There is nothing
which has so distinctly characterized the tiend of modern therapeutics,
and separated it from the empirical methods of the past —which have
crowned our materia medica with vast masses of useless rubbish, as
the contribution of physiological products to the control of disease.
It is strange that we have moved so long in the light of physiological
discovery thrown upon us by the microscope, the spectroscope, and
the ingenious apparatus which makes our laboratories more wonderful
to the untutored mind than were ever the alembics of alchemy to any
age of romance and sui)erstition — it is passing strange, I say, that we
have so long overlooked the very principles upon which alone a
scientific system of therapeutics could ever be established — the func-
tional relations of the cellular elements of the organism. As long ago
as that stormy time in the history of the British Association, when
the Thompson-Tyndall prayer-test was convulsing the religious and
scientific world, a no less interesting discussion grew of that contest
upon the subject of spontaneous generation. So strong was the
antagonism developed that it affected even the terminology of physio-
logy, Dr. Lionel S. Beale, the recognized champion of the "orthodo.x"
*A paper read before the Section on Practice at the Forty--ixih Annual Meeting of the .\merican
Medical Associatio-i, held at Baltimore, May 7th to lotli, illustrated upon the screen, showing
niierophotograhs of protonuclein and its action upon the leucocytes of ihe bloc J.
THE CANADIAN MEDICAL REVIEW. 189
party, clinging to the principle of " vital force" and giving to the
blastema of the ultimate physiological unit of the organism the name
of bioplasm, while Professor Huxley gave the name of protoplasm to
that which he and all of his school recognized as the " Physical Basis
of Life." Nothing then was known of the exact structural and func-
tional character and relations of this peculiar cell substance, which
appeared to act so differently under conditions apparently the same.
It remained for later physiologists to show just what part this ultimate
vitalized material played in the great drama of physiology. It was
found that both these great scientists were correct, but viewing this
cell-blastema under different conditions their definitions differed
accordingly, yet led up to the same result, as in the case of Coper-
nicus and Ptolemy, or to speak poetically :
" Like that target discussed by the travellers of old,
Which to one appeared -arjent, to one appeared gold ;
To him ever lingering on doubt's dizzy margent,
Appeared in one moment both golden and argent."
The first step in what may be called the new physiological system
was taken when with the improved mechanism of the microscope it
was demonstrated that of the two kinds of corpuscles that float in the
plasma of the blood, the larger and white corpuscle, the leucocyte,
was in every respect a .perfect cell, possessed of a cell wall, which
Dr. Beale distinguished as " formed material," a blastema or plasmic
granular substance, in which floats a body called the nucleus, and
within that the nucleolus. How many of these may be thus involuted,
can no more be estimated than can the problem of time and space be
solved by the finite mind.
The next step towards establishing our new physiological system
was taken when the leucocyte was found to be the real unit of the
organism, the agent through which all nutrition is accomplished. Up
to a very recent date it was believed that all nutritious material which
had been operated upon by the digestive agents passed directly into
the general current of the circulation, floating freely in the plasma of
the blood till it reached the capillaries, and then by a reversed osmotic
process was taken up by the individual tissue cells, only that part
being taken up by them which was necessary to the support of that
structure represented by the cell — the rest passing on in a like manner
to the other structures, until all the parts of the organism were
nourished.
The red corpuscle was organized as the oxygen carrier of the system,
and the eliminator of carbonic acid, but neither the origin nor the
I90 THE CANADIAN MEDICAL REVIEW.
function of the white corpuscle was in the least understood by even
the most skilful observers. Later investigations, however, proved the
identity of the le,ucocyte with the lymph corpuscle, which was itself
supposed to possess as the simplest original cell, metabolic or tissue-
forming functions. This gave a new importance to the leucocyte
and when to this was added the recognition of the pus corpuscle in
retrograde metamorphosis as nothing more or less than a leucocyte
under altered conditions, it was not long before its true significance
as the real tissue-builder of the organism was fully established. A
peculiar movement of the leucocyte as it goes along through the
current of the blood had long been noticed, on account of its
resemblance to that of the amceboid movement, by which it changed
its form apparently at will, becoming often so elongated and slender
that it slipped through the walls of the blood-vessels and held high
carnival in the surrounding tissues. All this pointed to some mysteri-
ous power or function, as yet unrevealed to the eye of the physiolo-
gist. A closer study of its morphological characteristics proved that
there were several forms of leucocytes, differing in the number of
nuclei which they possessed. The simplest, those having but one
nucleus, were called mononuclear, those possessing two or more
nuclei were called multi, or polynuclear leucocytes. In these it was
seen that the amoeboid movement was most active. Vierordt, who
has made the most accurate observations upon the blood of any other
physiologist perhaps, found the numerical relation of the leucocytes
to the red corpuscles to be in health in the ratio of i to 671.
Now, we are prepared to understand the next step in the functional
history of the leucocyte. These bodies, differing in size, shape, and
number of nuclei, were observed to swell up and burst, pouring out a
plasmic, granular mass, which appeared to be in a state of active
molecular vibration. The nuclei came forth from the breach in the
cell wall with some of this blastema hanging closely around it, while
the rest of the blastema with the ruptured cell wall floated off in the
blood current. Where there were two or more nuclei, each one became
rapidly a perfect cell with its nucleus and nucleolus, and in this way
was established a great increase in the number of leucocytes. This
process of cell proliferation, it will be seen, lies at the foundation of
all nutrition.
The next phenomenon observed was what might rationally have
been expected to be established — the taking up by the leucocytes of
the proteids which are delivered to the blood by the absorbents after
digestion is complete.
As soon as these proteids get within the walls of the blood-vessels,
THE CANADIAN MEDICAL REVIEW. 191
they are immediately attacked by the leucocytes and taken into their
cell walls by that osmotic process, which is the basis of all physical
action in the organism. Mingling with the blastema of the leucocyte,
these proteids become suffused, as it were, with a certain molecular
activity imparted to them through the influence of the nucleus, some-
thing like that observed when an electric current renders nascent
certain chemical agents that without it are negative or inactive. It is
this vitalized pabulum to which physiologists have given the name of
nuclein.
The next step in physiological evolution is the appropriation of this
pabulum by the individual tissue cells of the body as it passes through
the capillaries. And here it must be noted that no assimilation of any
nutritive substance (except of inorganic origin, as water, etc.) can take
place through any medium but that of nuclein, and it is in the mul-
tinuclear form of leucocytes that we find it developed. It has long
been known to physiologists, but its wonderful place in the economy
of the organism was never known until the close study of the
leucocyte developed its origin and function, and in this way cleared
up some of the most hidden mysteries of the organism, and placed in
the hands of the therapist the most wonderful agent of therapeutic
power yet known to scientific medicine.
To return to our panorama of nutrition, seeing that the proteids
must all report to the leucocyte and be stamped with their nuclear
influence before delivery to the several tissues, the bursting of the
leucocyte is readily understood, for by this means the nuclei are set
free to become new cells, and a great quantity of this cellulized tissue-
pabulum is poured out into the circulation, bathing with food every
hungry cell of the several tissues through which it floats, each cell
taking up that which is necessary to its molecular activity and return-
ing to the current that which belongs to other and remote tissues of
the organism. This conversion into tissue through the circulatory
system, of material, lifeless in itself, is the most wonderful phenomenon
presented to the human mind. We can not, of course, explain the
affinities by which certain kinds of pabulum are accepted and others
rejected by the several tissue-cells of the body any more than we can
explain the affinities between the sexes, often so seemingly astounding.
We know this, however, that the change which goes on is the elabor-
ation of a vitalized or cellulized substance which is capable of entering
at once into tissues as soon as it meets the various cells possessing this
power of elective assimilation. This primal cellulized pabulum has
therefore been appropriately called nuclein from the mode of its
generation, and when operated upon by the individual tissue-cell it
192 THE CANADIAN MEDICAI. REVIEW.
becomes protonuclein, after the analogy of Prof. Huxley's nomencla-
ture, which represented its real origin. This substance is rich in
phosphorus, and has been separated in active form from the lymphoid
structure of the body, as we shall see later.
We are brought now face to face with one of the most formidable
problems of physiology, the solution of which will destroy many of our
old pathological ideas, upon which so many therapeutic systems have
been wrecked. Up to a very recent date in the history of pathology
leucocythemia was considered a specific disease. Upon the post hoc,
propter hoc principle of medical philosophy, the rush of leucocytes to
any point of irritation was regarded as a feature, or even as a distinct
stage of the disease. How vividly can the memory of some of you
recall the old professional saws, as they were called by those of us
who sat at the feet of the Gamaliels of those days, among which there
was none more familiar than the Ubi irritatio ibi fliixtis 1 We
answered almost all questions upon inflammation with this single
axiom, as we believed it. Often have I heard the venerable Gross
straighten his lofty form and declare in stentorian voice that imflam-
mation consisted pathologically of the rapid afflux of leucocytes I
How startled would he be to learn that modern physiology has
demonstrated that rapid afflux to be nature's reinforcing battalions !
Every white blood corpuscle which gathered about that point of irrita-
tion bore with it the materials of repair, and as still later investigation
has proved, also the power of overwhelming toxic germs, themselves
in their incipiency, and protecting the organism against their poison-
ous and deadly exudations.
As to the phagocytic action or cell-eating power of the leucocytes,
which has been strongly claimed by some observers and as strenu-
ously denied by others, it is after all a mere question of difference in
the manner of destroying toxic germs which has developed antagonism
among physiological observers. It is, as I have upon a previous
occasion already remarked, not at all necessary that because the
physiological or pathological function of one cell is lost in that of
another, we should in speaking of such action as a phagocytic or cell-
eating process, imagine a mouth and teeth and all the paraphernalia
of mastication, deglutition, etc. The result is the same, whether the
pathological germ is swallowed, destroyed, or neutralized ; so long as
the cellular influence of the leucocyte is the agent which accom-
plishes this, it is immaterial whether we use the term "phagocytic"
literally or metaphorically, but notwithstanding all the adverse criti-
cisms of the word as used in this connection, there is none given us
which more emphatically expresses the idea we wish to convey, and
THE CANADIAN MEDICAL REVIEW. 193
the difificulty of nomenclature is anyhow too great to Hghtly reject so
expressive a word, which, as bacteriologists and morphologists all
admit, does certainly most vividly express the primordial condition of
which this is the physiological analogue. In its last analysis, after all,
it is the molecular disturbance or change produced in the germ that
deprives it of its toxic power. This we know will effect even chemi-
cal action. Upon this fermentative processes depend. Isomerism is
another example of the effect of molecular arrangement or disarrange,
ment. Where can you find two substances more distinctly different
than sugar and gum arabic ? And yet they are exactly the same in
composition and in the proportion of elementary combination, the
difference in arrangement of the molecules being sufficient-to account
for the difference in chemical and physical properties. With these
examples before us— and I could, if time permitted, bring out many
others equally as striking— it is very easy to see how the slightest dis-
turbance of molecular arrangement in any germ will deprive it of its
specific character, and by investing it with certain cellular elements,
emasculate the most deadly of toxic bacilli and send them harmless
through the blood currents of the organism. Having, therefore,
found that it is within the leucocyte that all protozoio* material is
developed, that upon the proliferation of the leucocyte all assimilation
depends, it is but a step further to establish the action of the
leucocyte in resisting the effect of toxic germs, as well as divesting
them directly of toxic power. It would perhaps be more accurate to
define this action by the statement that they are capable in themselves
of overcoming the pathological influences which are being continually
introduced into that organism. To those whose daily experience
brings them face to face with the awful side of human life, I think I
can appeal with emphasis, when I state that there is scarcely a breath
we breathe, or a drop we drink, or a morsel we eat, that is not charged
with the germs of deadly disease, and if there were not in our organism
a distinct provision made for the resistance of such germs, to use a
Pauline expression, we should " die daily." When the tocsin of dis-
ease is sounded through the organism, it is the rushing of the leuco-
cytes that constitutes the first physiological response— to directly
resist a toxic agent, or supply the structure attacked with material for
nutrition or repair in case of lesion. And yet there are still those
among the ranks of intelligent practitioners who consider the increase
of leucocytes as an element or phase of disease itself, instead of
nature's effort to support her crumbling battlements. At this stage of
my argument, I shall, upon the strength of what may be microscopic^
ally demonstrated to be the function of the nuclein-charged leucocyte,
4
194 THE CANADIAN MEDICAL REVIEW.
make an assertion which I have no doubt will be considered somewhat
arbitrary. It is, that whatever of so-called specific effect lies in the
antitoxine obtained from the immunized animal, as opposed to the
bacillus and the toxine of diphtheria, is accomplished by the excite-
ment of leucocytosis, and after all the end is reached by the same
physiological process.
The ultimate aim of all antitoxic agents must be the overwhelming
of tlie toxic element of the germ, and this can only be accomplished
by a great excess of physiological tissue-building material. Let us ob-
serve the process by which this antitoxic effect is brought about. In the
first place, the physiological relation of protonuclein would of course pre-
clude the ide'a of its action as a direct specific antidote to a specific
poison, such as that observed between chemical agents, or even physio,
logical antagonists, as for instance the hydrated sesquioxide of iron
against arsenic, or atropia against morphia, or chloroform against strych-
nia. Were this the principle of the functional activity of protonuclein, its
therapeutic range would be limited to such an antagonism, but. as I
am prepared to show, by careful experimental records, its effect is first
observed when the system has been thoroughly charged with it, thus
preventing the expression of the toxic agent by a preoccupation of the
nutritive field, and an investment of the attacking germ. I have
often noticed a leucocyte, thoroughly charged with original nuclein,
adhere to the cell of a sarcoma, and after bursting itself, send the
round cell floating away in the field crenated and almost emptied of
its contents. Such effects have been observed also upon the blood
after days ot treatment with protonuclein. This appears to me to be
the very ultima thule of thtirapy ; and the question will be — has been,
very naturally asked after such developments: "If such be the
power of a substance capable of investing, controlling, and overwhelm-
ing toxic agents, where is the limit of its action ?" If I spoke the
truth boldly, as it should be spoken, I should answer that, properly
applied, I can see no limit of its resisting power. When side by side
with my own experiments I have observed what I admit to be the
wonderful effects of antitoxine in the organism on the bacillus and
toxine of diphtheria, I have, nevertheless, felt that protonuclein was
as far superior to it in pathological results as the whole realm of
pathology is greater than a single disease.
And now we come to the question of practical interest to the
general profession, " How is it possible to extract this delicate sub-
stance from the animal tissues?" and its corollary, "What are the
methods used to preserve its cellular activity ?"
There are three forms of nuclein material now before the profession .
THE CANADIAN MEDICAL REVIEW. 195
1 . Nuclein made from yeast.
2. Another preparation of nuclein taken from the animal organism
by chemical methods.
3. The third form, protonuclein, is a product taken directly from
the lymphoid tissues of the healthy animal, the thyroid and thymus
glands, the brain substance — within the area in and about the corpora
quadrigemina, the pituitary body and pineal gland— the pancreas,
spleen and liver. No chemicals are used in this process, the methods
of extraction being purely physical, and the protonuclein is kept
active by an investment of gum benzoin and milk sugar, which pre-
serves it indefinitely, just as the germ of a grain of corn is kept
potentially active by its environment. The activity of the protonu-
clein may be easily shown by dissolving some of the powder in dis-
tilled water. After the sediment has settled, draw off the supernatant
fluid and apply a drop of it to a drop of freshly-drawn blood. You
will see a most beautiful physiological panorama, instantaneous photo-
graphs of which I have here for your inspection. Protonuclein is
richer in nitrogen than the ordinary nuclein of the text-books. Its
formula, as far as it is possible to be chemically accurate in quanti-
tative analysis, is C.29 H4,, Nj,, P5 O-^.,, differing by about one equivalent
of nitrogen. It will be noticed how rich in phosphorus this wonderful
physiological agent is.
So much therefore for its preparation and extraction. The most
important factor in the problem is the answer to the questions, " What
will it do?" "What can it cure?" "What will it prevent?" in the
great battle between science and death. Were I to give free range
to my own confidence in the therapeutic power of protonuclein as
observed from day to day for the last six months, under the most
favorable circumstances and under the direction of experienced and
authoritative clinicians, you would discredit even the demonstrations
of this report. But if you will consider for a moment what a sweeping
therapeutic power must belong to any agent which is the normal
tissue-builder of the organism and the direct antagonist of its invading
toxic germs, you will see how difficult it is to limit its indication as a
therapeutic agent.
Its most pronounced results have been observed in tuberculosis,
sarcoma, diphtheria, tonsillitis, and la grippe. In the hospitals in
New York it has been used with general success in the following dis-
eases, besides those already mentioned : Abscess, anaemia (pernicious),
Bright's disease, carcinoma, colds, malaria, tuberculosis of bladder,
ulcers, and many others.
As to dose and mode of administration, I subjoin to this paper full
196 THf: CANADIAN MEDICAL REVIEW.
directions, which have been carefully prepared from the closest clinical
observations.
Nothing has been left undone to thoroughly test the practical truth
of what has theoretically been claimed for protonuclein as a therapeutic
power. I believe with others even more conservative and les.s
sanguine than I, that it will mark an era in therapeutics. Such
relationship between the pabulum and the individual ti-sue-cell of the
various structures of the body, seems to be the very last analysis of
function in the human organism. Indeed, it has been said by one
who occupies a high position as a medical teacher : " I feel assured
that protonuclein is to fill a most important place in the thera-
peutic resources— perhaps the most important."
Up to the time when therapy began to look to physiology for help,
our whole system was a vast accumulation of clinical reports without
one iota of determining philosophy — a vast labyrinth without an
Ariadne thread to guide the returning footsteps of our reason. I doubt
not that before the close of the nineteenth century our therapists will
look back upon the thousands of agents vaunted in the cure of disease
las the modern soldier gazes upon the spear and shield of ancient
Greece and Rome. The simplification of physiological methods has
been followed most naturally by the use of those physiological
principles of therapy upon which the normal curative conditions of the
organism depend, and without which no scientific system of therapeu-
tics could ever be formed.
Tendon Grafting. — A new operation for deformities following
infantile paralysis. At the meeting of the New York Medical Associa-
tion, October 15th, 1895 {Medical Record, October 26th), Dr.
Milliken presented a boy eleven years of age, upon whom twenty
months before he had successfully grafted part of the extensor tendon
of the great toe into the tendon of the tibialis anticus muscle, the
latter having been paralyzed since the child was eighteen months old.
The case which was presented showed the advantages of only taking
part of the tendon of a healthy muscle, which was made to carry on
the function of its paralyzed associate without in any way interfering
with its own work. The brace which had been worn since two years
of age was left off, the patient walked without a limp, the talipes valgus
was entirely corrected and the boy had become quite an expert roller
skater. Dr. Milliken predicts a great field for tendon grafting in these
otherwise ho[)eless cases of infantile paralysis, who heretofore have
been doomed to the wearing of braces all their lives.
ADVERTISEMENTS.
THE MOST COWENIENT
AMI
ECOAOMICAL METHOD
OF PRODIXT\G
LOCAL
AX^STHESIA
:;,;WiTH pat ent^'s pray a^nd "stopper.
0 N ir T H I , ? D O F ,-C T UAL^sTz^^T
ETHYL CHLORIDE EENGUE is an
anassthetic, which is at once rapid in
action, convenient to use, always re-
liable, harmless and inexpensive.
Put up in tubes containing 37 to 40cc., and terminating in a short tube with a capillary
orifice, upon which is fi.xed a copper screw-thread. On the screw is a cap, also of copper, which,
being lined with India-rubber, closes it so tightly that the Chloride is prevented from evapor-
ating, and can be used in the evact qiisviitity rt^quired by the case in hand. It is thus
extremely economical, as each bulb of El'HYL CHLOIUDE liENGDE contains sufficient
for 10 to 15 local anaesthesias. Supplied with Straight Stem or Curved Stem (as illustration).
The use of ETHYL CHLORIDE is without danger of^ny kind, and It can be applied
equally to skin and mucous membrane.
^^ Remember to specify ETHYL CHLORIDE'eENGUE.-^
Pwphlet and full particulars TIEIOS- LIE E JVHI^STGr cSC C3C:>
on application to -*. -». -i. _■_ ■» v_* «_^ v_^\ — /_^
25 St. Peter Street, Montreal.
CUT THIS OUT-
Bafe,
i8p
CANADIAN MEDICAL RE VIE W CO.,
Toronto, Out.
Enclosed please find $ i.oo, for which I request that you enter
my name on your list of subscribers to 'he REVIEW for one year
from iSg to
i8g At the expiration of this time, if not previously advised to
the contrary, you may retain my name as a subscriber, and I zvill
remit on receipt of bill.
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ADVERTISEMENTS.
. . THE , .
TRUSTS CORPORATION OF ONTARIO.
OflSces and Safe Deposit Vaults,
Bank of Commerce Building,
^^King Street, Toronto.
AUTHORIZED CAPITAL, - $1,000,000
CAPITAL SUBSCRIBED, - 800,000
Hon. J. G. A [KINS, P.O., Toronto, President.
Hon. Sir R. J. CARTWRIOHT, K.G.M.G., Kingston, \ ... „ ., .
Hon. S. G. WOOD, .... Toronto, /
The Corporation is accepted by the High Court of Justice as a Trusts Company, under the
approval of the Ontario Government, and is authorized to act as Executor, Admiiii-trator,
IN CASE OF InTESTACV, OR WITH WiLL ANNEXED. TrU8t«-e UNDER DEED, WiLL, COUKT
Appointment or Substitution. Receiver, Couimittee of Lunatics, and Custodian of
THR Estates and Properties of Lunatics. Guardian of Children, also as Agent for
Gxecutors, Trustees and others, thus relieving them from onerous and oftentimes dis-
agreeable duties.
The Corporation also acts as Affent in financial business of all kinds— Collecting of Rents,
Income, etc.. Issue and Countersigning Bonds, Debentures, etc.
Our Deposit Vaults are absolutely secure, and every convenience provided for the storing
of Valuables of all kinds at small expense. Wills appointing the Corporation as Exectitor are
received for Safe Custody free of charge.
The employment of the Corporation will be found prompt and economical. Solicitors placing
business with it are continued in the legal work thereof.
A. E. PLUMMER, Manager.
FERROL
A RELIABLE PREPARATION OF IRON AND PURE
NORWEGIAN COD LIVER OIL OF
AGREEABLE TASTE.
Useful in aU cases where COD LIVER OIL and IRON
. . . are indicated . . .
Baniple of FEllitOLi jjiven to any pliysiciau in rt'gular practice on application.
Toronto, Nov. 15th, 1893.
After carefully analyzing "FERROL," I am satisfied that it must prove a valuable acquisi-
tion to the list of medicinal preparations now before the public. Its administration in tuber-
cular troublis aucoinpaniod by aiitcinia must, in most instances, be efficacious.
Furthermore, 1 am of ihc opinion that it will prove a valuable remedy in children's diseases,
in which the administration of Cod Liver Oil, Iron and Phosphates is desiiable. 1 am not
surprised to find the list of physicians endorsing on the daily increase.
A. R. PYNP:, M.B., Dominion Analyst.
FERROL MANUFACTURING CO
HEADOFFce: 205 Spadina Ave., TORONTO.
. . . Retail by all the Le.iding Druggists . .
ADVERTISEMENTS. :
THE BEST ANTISEPTIC
F=OR BOTH INTERNKU T^ND EXTERNAL WSE.
Antiseptic,
Prophvlactio,
Deodorant.
LISTERINE
Non-Toxic,
NON-lHRlTANT,
NON-ESCHAflOTIO.
LISTERINE is a well-proven antiseptic agent— an antizymotic— especially useful in the manage-
ment of catarrhal conditions of the mucous membrane ; adapted to internal use, and to make and
maintain surgical cleanliness— asepsis — in the treatment of all parts of the human bodjf, whether
by spray, irrigation, atomization. or simple local application, and therefore characterized by Its
particular adaptability to the field of
PREVENTIVE MEDICINE-INDIVIDUAL PROPHYLAXIS.
LISTERINE destroys promptly all odors emanating from diseased gums and teeth, and will
be found of great value when taken internally, in teaspoonful doses, to control the
fermentative eructations of dyspepsia, and to disinfect the mouth, throat, and stomach
It is a perfect tooth and mouth wash, INDISPENSABLE FOR THE DENTAL TOILET.
Lambert's Lithiated Hydrangea.
FORMULA.— Each fluid drachm of "Lithiated Hydrangea" represents thirty Rrains of frksb
Hydrangea and three grains of CHE.MICALLY puke Benzo-Salicylate of Lithia. Prepared by
our improved process of osmosis, it is i.vvariably of definite and uniform therapeutic
strength, and hence can be depended upon in clinical practice.
DOSE.— One or two teaspoonfuls four times a day (preferably between meals).
Close clinical observation has caused Lambert's Lithiated Hydrangea to be regarded by
' physicians generally as a very valuable Renal Atterative and
Anti-Lithic Agent in the treatment of
URINARY CALCULUS, GOUT. RHEUMATISM, CYSTITIS. DIABETES H/EMATURIA, BRIGHT'S DISEASE,
ALBUMINURIA AND VESICAL IRRITATIONS GENERALLY.
We have much vahiable literat\ire upon General Antlseptic Treatment, Lithemia, Diabktm,
Cystitis, Etc., to forward to physicians upon request.
LAMBERT PHARMACAL COMPANY, St. Louis. Mo.
SOL. FERRI ALBUMINATL <flett»
Does not distil rb the most sensitive stomach. Contains Iron in its most assimilable form
May be combined with Strychnia and Arsenic. Dose, one to two drachams.
When Prescribing Specify "Flett."
FRED. W. FLETT & CO., - Pharmacists,
TELEPHONE 664 ... TORONTO.
WHEELER'S TISSUE PHOSPHATES.
Wheeler's Compound Elixir of Phosphates and Calisaya. A Nerve Food and
Nutritive Tonic for the treatment of Consumption, Bronchitis, Scrofula and all fonns of Nervous Debility.
This elegant preparation combines in an agreeable Aromatic Cordial, in the form of a Glycerite acceptable
to the most irritable conditions of the stomach: Bone, Calcium Phosphate Ca22P04, Sodium Phosphate
Na2HP04, Ferrous Phosphate Fe32P04 Trihydrogen Phosphate HsPOi, and the active principles of
Calisaya and Wild Cherrj'.
The special indication ot this combination of Phosphates in Spinal Affections, Caries, Necrosis, Ununited
Fractures, llarasmus. Poorly Developed Children, Retarded Dentition, Alcohol, Opium and Tobacco H.abit,
Gestation and Lactation to promote Development, etc., and as a physiological restorative in Sexual Debility
and all used-up conditions of the Nervous System should receive the careful attention of good therapeutists.
ISotable Properties: As reliable in Dyspepsia as Quinine in Ague. Secures the larjrest percentage
of Benefit in Consumption and all Wasting Diseases, " by determining the perfect digestion and assimilation
of food." When using it. Cod Liver Oil may be taken without repugnance. It renders success possible ih
treating chronic diseases of Women and Children, who take it with pleasure for prolonged periods, a factor
essential to maintain the goodwill of the patient. Being a Tissue Constructive, it is the best "general
utility compound " for Tonic Restorative purposes we have, no mischievous effects resulting from exhibiting
it in any possible morbid condition of the system. Phosphates being a natural food product, no substitute
will do their work in the system.
DOSE— For an adult, one tablespoonful three times a day, after eating ; from seven to twelve years of
age, one dessertspoonful ; from two to seven, one teaspoonful ; for infants, from five to twenty drops accord-
ing to age. Prepared at the Chemical Laboratory of T. B, WHEELER, M.D., Montreal, P,Q.
To prevent substitution, put up in pound bottles only and sold by all druggists at One Dollar.
e^ head the pamphlet on this subject sent you.
OMNIA TERRESTREA QUAE VENUNT, PURGAT.
'* Harvey's" Peroxide of Hydrogen. H2 O2.
Three grades nianufactiirod, Xo. 1, No. 2, No. 3. No. 1 is medicinal and put up in sealed
bottles: full strength and absolute purity guaranteed ; will retain its germicidal power undim-
inished for years. No. 2 and No. 3 not O. P. and cheaper grades.
Harvey's Acrolozone. Cs Hs 0:j v O3.
A valuable therapeutical agent, prevents fermeiitMt ion of the food in the stomach, Dys-
pepsia, Gastritis, Ulcer of the Stomach. Heart-Iiurn. etc. Guaranteed pure and full strength
always.
Manufacturing
Manufactured SC /^ /Y 7/ Chemist,
by- y^^^^^ //. Ah^J7^/^jy Todmorden,
Near TORONTO
I'HE IDE A I.
HYDKO-CARBON
COD LIVER GLYCERINE.
(Japible of mixing' with water, requires no
digestion, but is readily absorbed.
Stimulates digestion.
Contains only active, soluble medical priii(-i])les.
Will not become rancid.
Will not decompose.
Mixes with all remedies, making it a preseiip-
tion remedy.
Will show decided result within 24 hours.
Kull dose is one teaspoonful.
Is pleasant, and l)oriie by the most delicate
stomachs— even infants.
COD LIVER GLYCERINE
COMPARISON,
'Gl.YCEROLE
MOKIIHC^."
COD LIVER OIL,
Or its Emulsified Coiiibiiuitions.
Cannot be completely digested.
Oppresses the stomach.
Contains inert and insoluble substances.
(.'ontains animal matter and other putrefactive
and rancid-bearing substances.
Exposed to air, becomes rotten with germs of
decomposition.
Must be administered alone.
Must be taken from four to six weeks to see
any medical results.
Full dose is two tablespoonfuls.
Is olfensive.
I woidd respectfully call the attention of physicians to the tact that I liave received a large stock of the
above preparation, and would be pleased to have them call and examine it.
HARBOTTLE'S Rossin House Drug Store.
MAGNETIC ROCK OIL. ! ^^m^^vy^y^l-v^^^^
Trade
Marked
JO=HE
Antiseptic, Anodyne jiiul I'ropby lactic,
Non-Irritant For External and
Internal Use.
This Oil is highly recommended, and possesses
.properties of great value as a local app'ication
in diseases of the skin, and in Burns, Bruises,
and in Acute and Chronic Rheumatoid and
Tuberculous Affections. It is sought to intro-
duccTHIS INVALUABLE THERAPEUTIC
AGENT exclusively on its MERITS, and for
this reason the Profession is appealed to through
the cohinms of a Medical Journal.
Physicians are respectfully invited to test
the Oil in any and every way they may deem
advisable to verify its merits. Oil. prepaid to
physicians, 6()c per can.
ONTARIO SUPPLY CO.
77 Victoria St., Toronto.
Agents for Canada.
A RTIFICIAL
Established
BEST LEG WITH WOOD OR
RUBBER FOOT. AND WOOD
OR ADJUSTABLE LEATHER
SOCKET
$50 '470
Arms ^''*'' •*"" ''"'* sock-
r— — r et Wrist Joints.
These limbs have been en-
dorsed by such men as Prof.
Esmarch ; Valentine Mott_ M.
D ; Willard Parker, M. D.; Gordon Buck, M. D.; and
scores of other eminent members of the profession.
We make one-fourth of all Limbs Supplied the
U. S. Government for Pensioners.
-TRUSESS,-
ELASTIC STOCKINGS, CRUTCHES, &C.
Send for catalngui- and state particulars,
GEO. R. FULLER, BOX 2112
ROCHESTER, N. Y.
EjIlPIBE ELflSTiG 6HNDII&E,
SPECIALLY ADAPTED FOR
VARICOSE VEINS.
We invite the attention of the Medical and Surgical
profession to the various merits combined in our
liai!da::es :
1st. ITS POROSITV- the greatest in the "Empire."
It never causes itching, rash or ulceration under the
I aiidage.
■2nd. ITS ELASTICITV, which will enable the sur-
geon or nurse to put it on at any required tension, and
which will follow a swelling up or down, as the case
mav be, a feature unknown to any other bandage.
3rd. ITS ABSORBENT PROPERTIES— greatest in
the " Empire."
4th. ITS EASY APPLICATION to any part of the
body, not being necessary to fold over, as with other
bandages, as it follows itself with equal uniformity
around any part of the abdomen.
.=ith. ITS SELF-HOLDING (QUALITIES. No bother
with pins, needle and thread, or string, so tiresome to
surgeons, as simply tucking the end under the last fold
insures its permanent stay, until its removal for pur-
pose of cleanliness.
6th. The onlv Bandage that is SUPERIOR TO THE
ELASTIC STOCKING for varicose veins.
Send SI. 00 for 3-liicli by 5-yard Stretched
Bandage.
THE EMPIRE ABDOMINAL SUPPORTER
Is superior to all others for the following
reasons :
Ist. It adapts
itself to every
movement of
the body, giving
strong and even
support.
2nd. It pro-
duces warmth
without irrita-
tion or sweating,
as it is pertectly
ventilated.
3rd. In preg-
nancy, CDrpu-
lency, tumors or
other cases of
enlai^gement of
abdomen, it sup-
ports the weight
of the body from
the backbone, re-
lieving the sin-
ews of their over-
work.
4th. Its easy
appliance (lace
and drawn on
over the head or
feet).
5th. It is cheap,
durable. It can
be washed if
soiled, proper
care being taken
to cleanse in
1 ukewarm water,
and dry in the
shade.
In ordering
give the measure
of the abdomen.
The Supporter
ehould be from
four to ten inches
larger, accord-
ing to the degree
of support re-
quired.
PBrrSICIANS' NET PRICES— 8 inches wide, $2.50 ; 11 inches, $3.00.
THE
EMPIRE UMBILICAL TRUSS
Abdominal Supporter with
Button inserted at the
navel.
Is made of the same material, and pos-
sesses the same merits as the Empire
Elastic Bandage and Empire Abdominal
Supporters, and is pronounced by all who
have seen it to be the BEST IN THE
WORLD. All of our goods are sent free
by mail iipoii receipt of price, and moiiey
refunded if not satisfactory.
In ordering, give the measurement of
the abdomen.
Physicians' Net Prices.
- $1 26
Infant
Children
Adult
2 50
i 00
Manufactured bj the Empire Manufactufing Co., 20 Spring St., Locliport, HI, U.S.*.
ADVERTISEMENTS.
COLLEGE OF PHYSICIANS AND SURGEONS
The Preliminary Lectures will begin Septr-niber 16lh, 1895. The regular Annual Ses.sion will
begin October l.st, 1895, iitid continue six ni()nth8.
For a catalogue or other information write DR. TH03IAS Ol'lE, Dean,
College Buildinj. Cor. Calvert and Saratoga Sts
Medical Practice and Partnership Office
ROOM 11, JANES BUILDING
KING AND YONGE STS., TORONTO.
OPENED FOR THE CONVENIENCE AND PROTECTION OF THE PROFESSION.
For the Purchase and Sale of Practices. The Purchase and Sale of Suitable Properties.
The Arrangement of Partnerships. Securing Eligible Openings.
Assistants. Locum tenens, and Office Students.
83" All Transactions and Communications Strictly Confidcntial.'^X
Letters must be direct from Medical Practitioners, and must enclose stamp for reply,
otherwise they will remain unnoticed.
DR. W. E. HAMILL, - - Room 11. Janes Buildirg, TORONTO
Physicians, Druggists and Dentists
Desiring to locate in the Pacific Coast States, or purchase an established
business, should address the MEDICAL EXCH.\NGE BUREAU.
DAVID D. LYNCH, Manager, - - - - PORTLAND, OREGON.
ACCIDENT INSURANCE. ^
The Employers' Liability Assurance Corporation .|
(LIMITED) J
OF LONDON, ENG. j
Capital $5,000,000 (Five Million Dollars) j
Spoc'al Policy covering Physicians and Surgeons ag.a'nst Blood Poisoning. ^
For rales and further information apply to .
C. W. I. WOODLAND j
'PHONE 1916 Chief Agent lor Ontario, 23 Toronto St., Toronto \
?t. --^- ^ ^ ^t. — -»■- ''^^^ — '^ — -^ — '^^ 2>- 1.- ... 2--.^- ... ^^ ^ -^ -*• -*- -*- - .^- - ...- .1^ iol
ADVERTISEMENTS.
SReOIMU NOTIOe.
PHYSICIANS.
If you hare a case of Eczema or any skin disease tbat vou consider incurable, send for a
sample of ECZAMEN, which is invaluable in all skin affection. It destroys all parasites in the
skin, and is prepared from pure ingredienls not at all poiacnous or corrosive. Send 10 cents in
stamps for sample box.
TH!> IS A »IEDICINE FO.t PHYSICIANS ONLY.
In prescribing, write thus:
R Eczamen = 11. (Bond's)
Apply twice daily.
LYMAN BROS. & CO.,
Wholesale Agent.
J. R, BOND,
Manufacturing Chemist,
448 Yonge St., Toronta
...All Physicians are Prescribing...
PIL ORIENTALIS (THOMPSON)
Containing the New Aphrodisiac "Ambrosia Orientalis"
Which the Medical Profession endorse as without a rival, linown to Ph.,rniacy
for Loss of Erectile Power and Impotency.
In the Oriental Pill the profession have a formula designed with special reference to the
Klands of the Reproductive Organs of both sexes, which will incr. aso their activity
and promote their secretive powers.
5e Ambrosia Orientalis grs. 2
Extract Saw Palmetto gr. J
Zinc Phosphide gr. J
Strychnos Ignat gr. J
with Capsicum and Aromatic Powder.
Indications. — Impotency (functional and congenital). Spermatorrhoea, Sexual D'jbility^
Weakness of the Bladder, Test( s. Mammae, or Ovaries. Prostatities— valuab e as a diuretic.
All cases of loss of nerve power, Amenorrhea, Dysmenorrhea, Leucorrhoea, Melancholia,
Hysteria, Sexual Apathy and all diseases of the female reproductive organs may be greatly
benefited by the use of this pill.
One eminent gynaecologist writes:
'• The Extract will prove itself a valuable addition to our materia medica for many female diseases," and
that "the Oriental Pill is very reliable, and will, no doubt, take the place of Daniiana. For if Damiana has
any aphrodisiacal action, it is very temporary, and the reaction is weakening and injurious."
Another physician, who has a large city practice, says :
"The result in eighteen cases (impotency, etc.) v/as very satisfactory," etc., etc.; also that "the
Oriental Pill has secured me many new patients."
A Virginia practitionf r says :
" The Pil Orientalis haa given me more satisfaction than any other remedy that I have tried for the last
thirty-five years for the loss of sexual power."
PRICE, ONE DOLLAR, BY MAIL.
In boxes, containing 12 bottles, plain label, for dispensing, S8.50 net.
For literature, etc., address
THE THOMPSON LABORATORY,
r.O Box 553. WASHIXUTON, D.C, U.S.A.
CHINA HALL.
Established 1S64.
TEA, BREAKFAST m DINNER SETS
... In the Latest Decorations . . .
RICH CUT GLASS.
BANQUET LAMPS.
•MPfcCOB/.TtP CnjN*
JUNOR & IRVING,
19 Kin^ St. East, Toronto.
ADVERTISEMENTS.
SPECIAL NEW LINES.
T\\EO\)ORt SKVi\i\i, .NirR?,';si^.T Ulanufaciorer
BY APPOINTMENT
To the Principal London Hospitals and Colleges,
91 SHAFTESBURY AVENUE, LOITDOIT, W.
IVe^^v Antisf^ptio IiisstniiiioiitsBs.
No. 55.— Skull's Antiseptic SursTioal S t. in Nickel Silver Folding Case forming:
trays for Solution, size 7 x 'i\ x 1 inclies, cont iiiins- —
4 Scalpels, assorted; 1 Cartilage Knife; 1 Dissi^cting Forcep^i; 1 pair Scissors, straight; 1
Double Blow Pipe ; 1 Set Chain Hooks: Needles in slide metal case.
The above Set, nickel plated, complete, tn Doeskin Pouch, 1 5s. 6d.
No. 15. — •vkull's Antiseptic Dissect njf I'ocltet Cjise, in Nickel Silver Foiflinff
Case, with movable Metal Fi anics, forming' trays for Sulntions, size 6x2x1
inches, containing'—
2 Scalpels, assorted; 1 Straight Scissors, probe point; 1 Curved Scissors; 1 Plain Artery
Forceps; 1 Artery Forceps with Mouse Teeth; 1 Artery Forceps with Side Catch ; 'l
Director with Aneurism Needle ; 1 Probe, buttoned ; 1 Probe with Myrtle Leaf.
The above Set, nickel plated, complete in Doeskin Pouch, £ 1 1 Os. 6d.
No. 21. -Skull's Antiseptic Surgical Pocket Case, in Nickel Silvei- Folding
Case, with movable 3Ietal Frames, forming trays lor Solutions, size 6 x 3i x 1
inches, containing —
3 Scalpels, assorted ; 1 Straight Scissors ; 1 Curved ditto ; 1 Artery Forceps with Mouse
Teeth ; 1 ditto with Slide Catch Disjoint ; 1 Hsemost Forceps. Pean's ; 1 Director with
Aneurism Needle ; 1 Sharp Double Scoop ; 1 Fine Sharp Hook ; 1 Probe with Myrtle
Leaf ; 1 ditto, buttoned ; 1 Needle Holder ; 1 Card Silk.
The above Set, nickel plated, complete, in Doeskin Pouch, £2 2s
'Every Description of Surgical Instruments and Appliances kept in Stock or Made to
Order. The Cheapest and Best House in the Trade.
A TRIAL SOLICITED. ESTABLISHED 1S63.
TMB LT^TEST INiZENTIOlS
SKULL'S OKONITE TRUSSES for H r ia
(RUPTURE).
AWARDS— Gold Medal, Paris Exhibition, 1889 ; Gold Medal, " World's Fair," Chicago, 1893
•^SKULL'S OKONITE TRUSSES for Rupture are in all respects the most perfect and unique instruments
ever offered lo the public as mechanical supports and remedial appliances for any form of Kupture or
Internal Prolapse. Thtse trusses are of the best possible manufacture ; they are self-adjusting, light
and comfortable. The external surface being compl tely covered with a non absorbent material
(Okonite), of a flesh color, resembhng- ivory, they cannot be detected when bathing ; they are . bsol-
utely impervious to moisture, perspira ion, and the acid excretions ot the skin ; cannot rust or '.et
out o order, cause no cutaneous irritation, will hold securely any size protrusion without pain, may
be washed when necessary with impunity, and can therefore be worn any lenjjth of time in any
climate without becoming offensive, hs is the case witn those constructed with leather, elastic, and
other objectionable materials of a porous character.
^ftKULL'S OKONITE TRUSSES for Rupture weijjh only a few ounces, and, being practically indestructble.
Can be guaranteed t<i last a lifetime, thus involving no further expense i o the purchaser beyond first
cost, and the undoubted advantages they possess over every other truss extant onslituie them aa
absolutely tlie best, and therefore the cheapest tha can be procured. The following ar ■ .• few extracts
from the leading medical journals : —
The Lancet — " Skull's Okonite Trusses are the nio<t effective we have ever noticed."
British Medical Journal — "They are scientifically construct d, and give perfect support in all cases."
iledical Prexs and Circular—" Will no doubt coiiie into general u-e."
lilustrated Mfiicul News — "We can with every confidence recommend them to all sufferers from Hernia
'(Rupture) and Prolapsus."
Thousands of Unsolicited Testimonials from all Parts of the World.
NOTICE— I ernplny no travellers or agents, and they are only supiilied direct, packeil in uooii cases, with
Slain address label.s. by rettirn of mail on receipt of P. O. Order or B.nk Draft, made payal le to THEODORE
KUIjL, .Shaftesbury Avenue, London, W.
rSKULL'S NEW OKONITE TRUSSES are manuf ctured in three di-tinct qualities at the following prices.
BestQIy. Med.Qlty. Com.Qlty.
Sinsle Truss, fo • riglit or left sid.-, - each 4.">/6 3,5/o 25/0
D ubie Truss, for botli sides, ... «• 91/- 7./- 51/-
M BA8URBMENTS Requirkd. — The entire circumference round the body two inches below the top of the hips,
In a line with the protrusion. State if the rupture is on the right, left, or both sides, or at the navel, and about the
■■iae of protrusion, and any special characteristic of the displacement.
THEODORE SKULL, Surgical IiiNtrunient and .^pplianc maiiiirartiirtT,
•1 SHAFTESBURY AVENUE, LONDON, W. (Two mintites' walk from Piccadilly, Cxford and C;mbride9 Circase:.
ESTABLISHED 1863
Manufacturer of all kinds of Surgical instruments, Trusses, Belts, Obstetric Binders, Elastic Stockings, Knee
•C»p«, Anklets, Suspensory Bsuidages, Enemas, Syringes, Pessaines, Rubber (Joods. etc. Kull particulars mailed free.
ADVERTISEMENTS.
We
have them
on the List.
IB I
'■^-i 5 Grains each. ^_^ . "f j
#1 LACTOPEPTINE /
"*'
t. laclopeptine conuiinsjil known SubsLmccsT
T employed byNaUireinllieDigesiknioial
kinds of Food.
». SupfriorloalloiherReinaiicsiorDj.s'
> pepsialndigc-slion and kindred ail- <'
V men(s dueloDijJcsiiveOi'hiiili; /^W
*; Dost?ro4 lAeuiS/infRfArHMfAt jt
* THf NfWrORK PMSMAMl KSSOCMTlOl* ,«*i
* -» NfW rORK. * i.v
1
Inasmuch as the tab-
1ft method of medi-
cation has become so
popular, both with
physician and patient,
we have, at the request of a number of
Practitioners, added Lactopeptine Tablets, 5 grs.
each, to our Hst. To further increase their therapeutic
efficiency, as well as to add to their palatabilit)-, we
have incorporated with the Lactopeptine a small
quantity of the digestive principle of the pineapple
juice, which recent researches have shown to possess
considerable digestive power. To render impossible
any substitution of inferior products, each individual
tablet is plainly stamped with the initials N. Y. P. A.
Always look for these letters, doctor, when d"s-
pensing Lactopeptine Tablets, and caution your
patient to do so w^hen you prescribe
them. %a«^B^WS7»M[M w^Wiki^-<^
Put up in bottles containing
100 3-gr. Tablets and 50 s-gr. Tablets.
Canada Branch :
30 Wellington St. East
TORONTO.
xx
ADVERTISEMENTS.
XlhoiiisattTids off Plhysacians i
oo 00 are now lUsSinig . , t
team SterS liters \
at Hospitals and in their offices, for Sterilizing
Instruments, Dressings etc., and recommending
the Family Sizes to their patients for Sterilizing
or Pasteurizing milk.
We make Sterilizers for every purpose, and
have circulars giving complete information.
Address,
WiLMOT Castle &. Co.
112 ELM ST, ROCHESTER, N. Y.
SUBSCRIPTION
si.oo
PER ANNUM.
Now is about the rig^ht time to
■ send it to the
U0n medical Review Go.
TORONTO, ONT.
DYSP
Also Special Dia
a7id Fatrnl Bi^cu
I iirlvnlid
Pamphlets
Write i' arwell &/iliiuei
FLOUR.
Barley Crystals,
Pantry Flour,
Europe.
pies Free.
.ertowiVN.y., U.S.A.
BA
IS'ew Diuretic, II
Gluten Dyspepsia
Pamphlet
Unrlviilt-a ill
Write Harwell
CRYSTALS
i'c Cereal; also
i Diabetes Flour.
mples Free.
»k Heulem, or
.N.Y.,U.S-A.
TELEPHONl
1963
presentation
Addresses
"fST^ErBT A. H. HOWARD, R.C.A.
.53 Kins St. E., Toronto
ADVERTISERS IN
The Canadian fledical Review
Beoeive Prompt and Ample Betarns for their Money Invested.
ad\'ertisemp:nts.
™b standard
? WFE kSSVlRMlCE CO.
..OF. .
EDINBURGH, SCOTLAND.
ESTABLISHED 1825.
HEAD OFFICE FOR CANADA, - MONTREAL.
TOTAL ASSURANCE, .... qVER $113,000,000
TOTAL INVESTED FUNDS, - - . '< 39,000,000
BONUSES DISTRIBUTED, ... « 28,000,000
ANNUAL INCOME, " 5,139,000
TOTAL ASSURANCE IN CANADA, - - " 14,000,000
TOTAL INVESTMENTS IN CANADA, - " 11,000,000
World-wide policies issued free of charge.
Thirteen months for revival of lapsed policies of five years' duration.
ROBERT CRAIK, M.D., W. M. RAMSAY,
Dttm Medical Faculty, McOill.
MEDICAL REFEREE. MANAGER.
A BICYCLE that is a BICYCLE is the
STEARNS
SEE IT AT ... . Built to ride with SAFETY.
THE BEST CYCLE CO.
'PHONE 582. iQo Queen 5t. West. - - TORONTO.
ADVERTISEMENTS.
Fielder Ulaqfg. Co.,
442 longe St., Toronto.
iOiamelled Ware for Hoepitals
and Physicians, and Cooking
Utensils of any description.
Catalogue
tmd Price*
an application.
Enamblled Instruinenf Trays.
Enamelled Bed Pans.
OFFICE OF
THE STANDARD MILK CO.,
OF ONTARIO (Ltd).
Telephone 3384 .
Toronto, Dec. 26th, 1894.
DOCTOR:
ONE MOMENT, PLEASE!
We do not want you to recommend our
milk hecause we advertise in, a Medical Journal,
but for the reason that our milk is better for
either the sick or well. If ou are not conversant
with our rruethod of handling, please do us the
favor of reading our descriptiv circular, or we
would he glad to Jiave you call and' examine for
yourself.
Yours truly,
The Standard Milk Co. of Ontario, Ltd.,
601 Yonie Street,
TURKISH BATHS
204 KING STREET WEST,
0pp. St. Andrew's Church.
Toronto
•Phone 12 86.
These baths are constructed upon the best scientific principles, •whereby purified heated air
is circulated through the rooms continuously, and the impure air is quickly removed. The
largest marble plungi/ bith on this continent. These baths have been highly endorsed by
the profession. Open every day and ALL NIGHT. For further particulars call or address
THOMAS T. COOK. Proprietor
MASSAGE
References from
Leading Physicians
'Phone 128G
THOMAS J. R. COOK,
Gradual' of West End Hospital for
Nervous Diseases, London, Eng.
EXSHAW'S BRANDY.
DELBECK CHAMPAGNE.
LEST A PIS CLARET.
Wi
. . . The above goods are highly recommended -where stunulants
are required, as their age and purity is guaranteed. . . ,
For Sai« by . . .
GEO. W. COOLEY, .
Imporkr of Bigh-Class Wines and Spirits,
567 YONGE STREET, .... TORONTO.
TtLEPHONE 3039.
}
v_
flDercbant Zlailore.
BUSINESS ESTABLISHED 1842.
Choice WOOLLENS, and Good
Work at Reasonable Prices.
ALSO A FULL RANUE OF
FURNISHING GOODS,
GLOVES,
NECKWEAR,
UNDERWEAR,
HOSIERY, Etc.
57 King St. West
TORONTO.
T*l*pfaoiie 2468.
MACNAB & CO.
274 Yonge Street,
TORONTO.
Manufacturers of
LADIES'
AND
MEN'S
FURS
ANTN
DIPHTHERITIC
SERUn. THIS
ANTITOXIN
IS PREPARED IN
Our Own Bacteriological Department
BY EXPERT BACTERIOLOGISTS
Every precaution known to the science has been taken to
insure its reliability ....
$3.50 PER VIAL.
Flach vial contains looo normal Antitoxin units, the full
curative dose for average cases
Directions for injecting the Serum accompany each vial.
Correspondence upon this subject respectfully solicited.
Parke, Davis & Cohpany
WALKERVILLE, ONT.